A4R43_20395 7f4df707fcba6066b3c7d3abced064c8 190 Gene3D G3DSA:2.60.40.1220 25 124 1.1E-22 T 14-10-2018 A4R43_20395 7f4df707fcba6066b3c7d3abced064c8 190 SUPERFAMILY SSF81296 24 118 7.7E-22 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_20395 7f4df707fcba6066b3c7d3abced064c8 190 Pfam PF04234 CopC domain 25 117 4.2E-23 T 14-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 A4R43_32140 664dd8b730f0aa43e35510a21b061eac 146 SUPERFAMILY SSF54534 61 134 2.22E-10 T 14-10-2018 A4R43_32140 664dd8b730f0aa43e35510a21b061eac 146 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 64 135 3.4E-11 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4R43_32140 664dd8b730f0aa43e35510a21b061eac 146 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 102 118 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A4R43_32140 664dd8b730f0aa43e35510a21b061eac 146 PIRSF PIRSF006092 1 139 6.6E-15 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A4R43_32140 664dd8b730f0aa43e35510a21b061eac 146 Gene3D G3DSA:3.10.50.30 64 145 2.6E-9 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 A4R43_08745 3cb8c0e9d8d373bf42b4b5066c18be5a 320 Pfam PF13280 WYL domain 144 314 8.3E-35 T 14-10-2018 IPR026881 WYL domain A4R43_08745 3cb8c0e9d8d373bf42b4b5066c18be5a 320 Pfam PF08279 HTH domain 7 62 1.0E-9 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_08745 3cb8c0e9d8d373bf42b4b5066c18be5a 320 Gene3D G3DSA:1.10.10.10 6 65 7.8E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08745 3cb8c0e9d8d373bf42b4b5066c18be5a 320 PIRSF PIRSF016838 1 320 1.1E-17 T 14-10-2018 IPR028349 Protein PafC A4R43_08745 3cb8c0e9d8d373bf42b4b5066c18be5a 320 SUPERFAMILY SSF46785 7 62 2.52E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_29340 71bd426e3f4fd9371a6a7816f1b45b43 258 Gene3D G3DSA:3.40.30.10 87 235 2.2E-46 T 14-10-2018 A4R43_29340 71bd426e3f4fd9371a6a7816f1b45b43 258 Pfam PF00578 AhpC/TSA family 96 220 9.6E-38 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_29340 71bd426e3f4fd9371a6a7816f1b45b43 258 PIRSF PIRSF000239 89 254 9.7E-25 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_29340 71bd426e3f4fd9371a6a7816f1b45b43 258 SUPERFAMILY SSF52833 93 242 6.42E-47 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1263 17.477 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Pfam PF04998 RNA polymerase Rpb1, domain 5 832 1200 2.0E-64 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 SMART SM00663 310 589 7.3E-170 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1253 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 SUPERFAMILY SSF64484 5 1254 0.0 T 14-10-2018 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 4.6E-81 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Gene3D G3DSA:1.10.132.30 722 856 4.6E-50 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Gene3D G3DSA:2.40.50.100 1031 1101 1.8E-64 T 14-10-2018 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Pfam PF05000 RNA polymerase Rpb1, domain 4 762 817 6.5E-8 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Gene3D G3DSA:1.10.40.90 449 491 4.4E-24 T 14-10-2018 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 560 1.7E-35 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 725 2.3E-25 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Gene3D G3DSA:1.10.1790.20 1015 1200 1.8E-64 T 14-10-2018 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Gene3D G3DSA:1.10.150.390 1202 1264 4.3E-29 T 14-10-2018 A4R43_33655 03062f747cc6acc3280a456f2d539b94 1303 Gene3D G3DSA:1.10.274.100 565 721 1.9E-42 T 14-10-2018 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 7 454 3.3E-114 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 SUPERFAMILY SSF51984 2 90 3.34E-13 T 14-10-2018 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 Gene3D G3DSA:3.40.50.720 1 89 3.6E-14 T 14-10-2018 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 SUPERFAMILY SSF53623 106 309 7.46E-48 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 Gene3D G3DSA:3.90.190.20 318 460 4.6E-37 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 Pfam PF08245 Mur ligase middle domain 111 292 1.4E-24 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 SUPERFAMILY SSF53244 313 456 5.49E-34 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 109 132 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 Gene3D G3DSA:3.40.1190.10 90 311 9.6E-52 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 7 50 1.2E-5 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4R43_16575 7e1577e3516f364807ce62e6eb1ac3de 466 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 6 456 30.968 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_04215 cb3952e720d4e19795228abd1cb6c9af 171 Gene3D G3DSA:1.10.10.10 81 161 5.3E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04215 cb3952e720d4e19795228abd1cb6c9af 171 Pfam PF08281 Sigma-70, region 4 103 155 1.1E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_04215 cb3952e720d4e19795228abd1cb6c9af 171 SUPERFAMILY SSF88659 93 161 2.43E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_04215 cb3952e720d4e19795228abd1cb6c9af 171 Pfam PF04542 Sigma-70 region 2 14 80 1.4E-5 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_04215 cb3952e720d4e19795228abd1cb6c9af 171 Gene3D G3DSA:1.10.1740.10 2 80 1.2E-8 T 14-10-2018 A4R43_04215 cb3952e720d4e19795228abd1cb6c9af 171 SUPERFAMILY SSF88946 3 89 2.39E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_04215 cb3952e720d4e19795228abd1cb6c9af 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 159 1.6E-15 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SMART SM00823 Phosphopantetheine attachment site 1456 1528 9.0E-29 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1483 1498 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SMART SM01294 1457 1524 0.0015 T 14-10-2018 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Pfam PF00698 Acyl transferase domain 565 878 1.4E-88 T 14-10-2018 IPR014043 Acyl transferase A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Gene3D G3DSA:3.40.366.10 565 862 2.0E-163 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Pfam PF00550 Phosphopantetheine attachment site 1458 1524 6.5E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Gene3D G3DSA:3.40.50.720 917 1422 6.8E-160 T 14-10-2018 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Pfam PF08659 KR domain 1168 1341 1.1E-56 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Gene3D G3DSA:3.30.70.3290 479 904 2.0E-163 T 14-10-2018 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SUPERFAMILY SSF51735 1164 1417 8.56E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SUPERFAMILY SSF53901 31 405 2.53E-105 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SUPERFAMILY SSF47336 1448 1536 1.96E-20 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1168 1343 2.8E-50 T 14-10-2018 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SUPERFAMILY SSF55048 687 752 5.49E-13 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 567 859 5.3E-115 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SUPERFAMILY SSF51735 963 1156 2.17E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Gene3D G3DSA:3.40.47.10 25 478 5.6E-192 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Pfam PF08990 Erythronolide synthase docking 3 27 8.7E-10 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SMART SM00825 Beta-ketoacyl synthase 36 457 1.2E-221 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Gene3D G3DSA:1.10.1200.10 1435 1529 2.6E-32 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 282 1.8E-93 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 528 4.5E-16 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 SUPERFAMILY SSF52151 564 855 7.32E-68 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07920 7f57c79aed4e82a6d3352295ad502d97 1606 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 407 5.2E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 Gene3D G3DSA:3.40.50.720 2 227 1.5E-70 T 14-10-2018 A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 53 64 9.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 106 114 9.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 145 9.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 226 3.2E-45 T 14-10-2018 A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 113 141 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 164 5.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 211 5.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 53 64 5.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 116 5.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 145 5.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37950 02424a00559dc8acd1ef8b45b99b1e02 230 SUPERFAMILY SSF51735 3 226 1.1E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_24700 315fa31f040bbe309c0d6ecf9d652684 427 Gene3D G3DSA:1.25.40.10 177 419 8.8E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_24700 315fa31f040bbe309c0d6ecf9d652684 427 SUPERFAMILY SSF48452 187 344 3.8E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_24700 315fa31f040bbe309c0d6ecf9d652684 427 Gene3D G3DSA:1.10.260.40 5 67 3.8E-10 T 14-10-2018 A4R43_24700 315fa31f040bbe309c0d6ecf9d652684 427 SUPERFAMILY SSF47413 9 62 4.79E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_24700 315fa31f040bbe309c0d6ecf9d652684 427 SMART SM00530 7 62 1.6E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_24700 315fa31f040bbe309c0d6ecf9d652684 427 Pfam PF13560 Helix-turn-helix domain 9 65 2.2E-6 T 14-10-2018 A4R43_15950 dfada26a0a42ececa778a192ea6c479d 251 SUPERFAMILY SSF52096 3 247 2.72E-57 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_15950 dfada26a0a42ececa778a192ea6c479d 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 211 1.5E-37 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_15950 dfada26a0a42ececa778a192ea6c479d 251 Gene3D G3DSA:3.90.226.10 3 250 2.5E-56 T 14-10-2018 A4R43_12005 c8a79f714db7993fc1f36a4fe0ea4558 345 Pfam PF00107 Zinc-binding dehydrogenase 163 257 3.4E-20 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_12005 c8a79f714db7993fc1f36a4fe0ea4558 345 Gene3D G3DSA:3.90.180.10 2 108 7.5E-11 T 14-10-2018 A4R43_12005 c8a79f714db7993fc1f36a4fe0ea4558 345 SMART SM00829 8 340 1.9E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_12005 c8a79f714db7993fc1f36a4fe0ea4558 345 SUPERFAMILY SSF51735 129 279 4.64E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_12005 c8a79f714db7993fc1f36a4fe0ea4558 345 SUPERFAMILY SSF50129 2 161 4.55E-19 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_12005 c8a79f714db7993fc1f36a4fe0ea4558 345 Gene3D G3DSA:3.90.180.10 109 329 1.6E-39 T 14-10-2018 A4R43_12005 c8a79f714db7993fc1f36a4fe0ea4558 345 Gene3D G3DSA:3.40.50.720 140 275 1.6E-39 T 14-10-2018 A4R43_20720 96e464a783e6f89e3c4c508a79e8d03a 396 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 151 280 1.4E-39 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_20720 96e464a783e6f89e3c4c508a79e8d03a 396 SUPERFAMILY SSF52540 110 363 1.32E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20720 96e464a783e6f89e3c4c508a79e8d03a 396 Gene3D G3DSA:1.10.8.60 285 344 6.4E-77 T 14-10-2018 A4R43_20720 96e464a783e6f89e3c4c508a79e8d03a 396 Gene3D G3DSA:3.40.50.300 109 284 6.4E-77 T 14-10-2018 A4R43_20720 96e464a783e6f89e3c4c508a79e8d03a 396 SMART SM00382 147 286 3.8E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_41110 3054709f3b1f3d791ff309b0ccef2ac9 288 Pfam PF13560 Helix-turn-helix domain 14 73 3.9E-10 T 14-10-2018 A4R43_41110 3054709f3b1f3d791ff309b0ccef2ac9 288 SMART SM00530 17 72 1.1E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_41110 3054709f3b1f3d791ff309b0ccef2ac9 288 Gene3D G3DSA:1.10.260.40 11 82 1.9E-9 T 14-10-2018 A4R43_41110 3054709f3b1f3d791ff309b0ccef2ac9 288 SUPERFAMILY SSF47413 12 70 4.22E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_34390 bafa76fa9ea0467d571cc18013eb9c61 447 Pfam PF04024 PspC domain 38 93 3.7E-13 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A4R43_34390 bafa76fa9ea0467d571cc18013eb9c61 447 SMART SM00387 349 443 0.0043 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_34390 bafa76fa9ea0467d571cc18013eb9c61 447 SUPERFAMILY SSF55874 348 441 4.71E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_34390 bafa76fa9ea0467d571cc18013eb9c61 447 Gene3D G3DSA:3.30.565.10 314 443 4.0E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_34390 bafa76fa9ea0467d571cc18013eb9c61 447 Pfam PF13581 Histidine kinase-like ATPase domain 347 407 4.6E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_17065 9ccd2f3d4bb0dd71b1436248c3dae8b1 485 SUPERFAMILY SSF51905 4 484 9.79E-59 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17065 9ccd2f3d4bb0dd71b1436248c3dae8b1 485 Gene3D G3DSA:3.50.50.60 2 115 7.8E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17065 9ccd2f3d4bb0dd71b1436248c3dae8b1 485 Gene3D G3DSA:3.50.50.60 198 321 1.2E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17065 9ccd2f3d4bb0dd71b1436248c3dae8b1 485 Pfam PF01593 Flavin containing amine oxidoreductase 12 483 5.3E-38 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4R43_17065 9ccd2f3d4bb0dd71b1436248c3dae8b1 485 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 5 484 4.7E-153 T 14-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 A4R43_18440 77f93cad5ec3264548507c32d7b74be9 313 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 53 250 8.2E-38 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4R43_18440 77f93cad5ec3264548507c32d7b74be9 313 SUPERFAMILY SSF51306 66 257 2.41E-44 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4R43_18440 77f93cad5ec3264548507c32d7b74be9 313 Gene3D G3DSA:2.10.109.10 194 263 1.3E-11 T 14-10-2018 A4R43_18440 77f93cad5ec3264548507c32d7b74be9 313 Pfam PF10502 Signal peptidase, peptidase S26 109 247 5.3E-8 T 14-10-2018 IPR019533 Peptidase S26 A4R43_18440 77f93cad5ec3264548507c32d7b74be9 313 ProSitePatterns PS00761 Signal peptidases I signature 3. 210 223 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A4R43_18440 77f93cad5ec3264548507c32d7b74be9 313 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 155 167 3.6E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4R43_18440 77f93cad5ec3264548507c32d7b74be9 313 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 205 224 3.6E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4R43_18440 77f93cad5ec3264548507c32d7b74be9 313 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 67 83 3.6E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4R43_28135 babff9be0df70cbb61c89622f7e42bd7 252 Gene3D G3DSA:3.40.50.720 11 246 2.2E-36 T 14-10-2018 A4R43_28135 babff9be0df70cbb61c89622f7e42bd7 252 SUPERFAMILY SSF51735 11 248 3.17E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28135 babff9be0df70cbb61c89622f7e42bd7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28135 babff9be0df70cbb61c89622f7e42bd7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28135 babff9be0df70cbb61c89622f7e42bd7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28135 babff9be0df70cbb61c89622f7e42bd7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28135 babff9be0df70cbb61c89622f7e42bd7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28135 babff9be0df70cbb61c89622f7e42bd7 252 Pfam PF00106 short chain dehydrogenase 12 199 3.9E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39710 8c11e5b17548552ea82c6bed1eb78e51 274 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 35 263 36.515 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4R43_39710 8c11e5b17548552ea82c6bed1eb78e51 274 Pfam PF01255 Putative undecaprenyl diphosphate synthase 42 262 2.5E-72 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4R43_39710 8c11e5b17548552ea82c6bed1eb78e51 274 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 208 225 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A4R43_39710 8c11e5b17548552ea82c6bed1eb78e51 274 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 35 262 2.0E-73 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4R43_39710 8c11e5b17548552ea82c6bed1eb78e51 274 SUPERFAMILY SSF64005 35 258 8.5E-82 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A4R43_39710 8c11e5b17548552ea82c6bed1eb78e51 274 Gene3D G3DSA:3.40.1180.10 3 257 7.5E-94 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 38.901 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 Pfam PF02629 CoA binding domain 7 103 1.1E-23 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 Gene3D G3DSA:3.40.50.720 1 129 1.2E-46 T 14-10-2018 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 SUPERFAMILY SSF52210 129 292 5.23E-46 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 Pfam PF00549 CoA-ligase 158 275 3.8E-14 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 291 1.3E-125 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 PIRSF PIRSF001553 1 295 1.6E-115 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 1.4E-33 T 14-10-2018 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 1.4E-33 T 14-10-2018 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 1.4E-33 T 14-10-2018 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 1.4E-33 T 14-10-2018 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 SUPERFAMILY SSF51735 1 128 3.29E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 Gene3D G3DSA:3.40.50.261 130 293 9.9E-60 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_34470 7188a4f5e73b580b70444a2ff15b58c4 296 SMART SM00881 4 104 2.7E-30 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_01650 ebaa977e611c3870e093379b2ebec5e8 491 Pfam PF13193 AMP-binding enzyme C-terminal domain 397 470 2.5E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_01650 ebaa977e611c3870e093379b2ebec5e8 491 Pfam PF00501 AMP-binding enzyme 12 387 2.7E-63 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_01650 ebaa977e611c3870e093379b2ebec5e8 491 SUPERFAMILY SSF56801 7 479 3.01E-104 T 14-10-2018 A4R43_01650 ebaa977e611c3870e093379b2ebec5e8 491 Gene3D G3DSA:3.40.50.12780 4 384 5.8E-75 T 14-10-2018 A4R43_01650 ebaa977e611c3870e093379b2ebec5e8 491 Gene3D G3DSA:3.30.300.310 385 482 3.2E-24 T 14-10-2018 A4R43_32130 82468b7809d16ac248fe3fe2259b8b63 514 Pfam PF13556 PucR C-terminal helix-turn-helix domain 446 501 3.3E-17 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_32130 82468b7809d16ac248fe3fe2259b8b63 514 Gene3D G3DSA:1.10.10.2840 374 507 1.4E-17 T 14-10-2018 A4R43_23265 120b063cf5863bd756c798354b4a7fa7 270 Pfam PF13560 Helix-turn-helix domain 5 83 2.7E-19 T 14-10-2018 A4R43_23265 120b063cf5863bd756c798354b4a7fa7 270 SMART SM00530 8 80 7.3E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_23265 120b063cf5863bd756c798354b4a7fa7 270 SUPERFAMILY SSF47413 28 77 2.82E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_23265 120b063cf5863bd756c798354b4a7fa7 270 Gene3D G3DSA:1.10.260.40 1 83 6.8E-9 T 14-10-2018 A4R43_23265 120b063cf5863bd756c798354b4a7fa7 270 Gene3D G3DSA:3.30.450.180 102 263 1.0E-13 T 14-10-2018 A4R43_27955 382e19419bb199380c5c41a10bb34ee0 364 Pfam PF06224 Winged helix DNA-binding domain 33 350 7.0E-80 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 A4R43_28075 58089273855bc7238e465fb7e5e2d341 271 Pfam PF00005 ABC transporter 47 177 7.7E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_28075 58089273855bc7238e465fb7e5e2d341 271 SMART SM00382 56 228 3.0E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_28075 58089273855bc7238e465fb7e5e2d341 271 Gene3D G3DSA:3.40.50.300 36 258 2.1E-41 T 14-10-2018 A4R43_28075 58089273855bc7238e465fb7e5e2d341 271 SUPERFAMILY SSF52540 45 242 3.06E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23145 0c8e299e184734b989484998a1f19f9c 208 Gene3D G3DSA:1.10.1740.10 9 94 1.8E-34 T 14-10-2018 A4R43_23145 0c8e299e184734b989484998a1f19f9c 208 SUPERFAMILY SSF88659 131 188 8.78E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_23145 0c8e299e184734b989484998a1f19f9c 208 SUPERFAMILY SSF88946 19 106 9.42E-24 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_23145 0c8e299e184734b989484998a1f19f9c 208 Gene3D G3DSA:1.10.10.10 125 193 2.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23145 0c8e299e184734b989484998a1f19f9c 208 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 13 199 1.9E-106 T 14-10-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_23145 0c8e299e184734b989484998a1f19f9c 208 Pfam PF08281 Sigma-70, region 4 134 184 6.1E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_23145 0c8e299e184734b989484998a1f19f9c 208 Pfam PF04542 Sigma-70 region 2 29 92 1.3E-18 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_23145 0c8e299e184734b989484998a1f19f9c 208 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 187 1.5E-27 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_18850 ba610746a5b1b655774f849ea5b9856d 423 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 147 401 1.8E-67 T 14-10-2018 IPR024516 Mammalian cell entry, C-terminal A4R43_18850 ba610746a5b1b655774f849ea5b9856d 423 Pfam PF02470 MlaD protein 41 116 1.1E-11 T 14-10-2018 IPR003399 Mce/MlaD A4R43_18850 ba610746a5b1b655774f849ea5b9856d 423 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 18 296 3.8E-50 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 Gene3D G3DSA:1.20.120.530 94 230 5.0E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 Pfam PF07729 FCD domain 104 223 9.0E-17 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 SUPERFAMILY SSF48008 99 232 3.4E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 SMART SM00895 103 224 4.1E-13 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 3.4E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 3.4E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 SUPERFAMILY SSF46785 11 84 2.7E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 Gene3D G3DSA:1.10.10.10 13 83 4.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 SMART SM00345 21 82 2.7E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19130 cac2a99620abf6d20c11ead99f67814a 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 2.5E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 SUPERFAMILY SSF55205 12 420 1.14E-101 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 Gene3D G3DSA:3.65.10.10 18 413 2.2E-128 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 14 416 2.0E-102 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 PIRSF PIRSF000505 4 423 1.6E-113 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 ProSitePatterns PS00885 EPSP synthase signature 2. 336 354 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 14 423 29.845 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 Gene3D G3DSA:3.65.10.10 26 241 2.2E-128 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A4R43_14210 92c93771eca7155f1b99680f5b065f88 423 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 19 421 9.8E-113 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4R43_08930 be84c76b2b1f57abe3dbae8ebf2a9069 315 SUPERFAMILY SSF46785 5 63 8.79E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08930 be84c76b2b1f57abe3dbae8ebf2a9069 315 Gene3D G3DSA:1.10.10.10 4 65 7.4E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08930 be84c76b2b1f57abe3dbae8ebf2a9069 315 Pfam PF08279 HTH domain 7 62 1.5E-15 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_08930 be84c76b2b1f57abe3dbae8ebf2a9069 315 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_08930 be84c76b2b1f57abe3dbae8ebf2a9069 315 PIRSF PIRSF016838 2 313 2.2E-26 T 14-10-2018 IPR028349 Protein PafC A4R43_08930 be84c76b2b1f57abe3dbae8ebf2a9069 315 Pfam PF13280 WYL domain 137 305 2.1E-29 T 14-10-2018 IPR026881 WYL domain A4R43_25525 73254cab9b7c03a2ab142adb1ad3e969 399 Pfam PF12698 ABC-2 family transporter protein 29 376 4.5E-48 T 14-10-2018 A4R43_15590 82117ce67b31531c7a502a3728a4f5a8 395 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_15590 82117ce67b31531c7a502a3728a4f5a8 395 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 142 2.4E-25 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_15590 82117ce67b31531c7a502a3728a4f5a8 395 SUPERFAMILY SSF51735 156 352 8.26E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15590 82117ce67b31531c7a502a3728a4f5a8 395 Gene3D G3DSA:3.90.180.10 4 381 1.1E-121 T 14-10-2018 A4R43_15590 82117ce67b31531c7a502a3728a4f5a8 395 Gene3D G3DSA:3.40.50.720 169 352 1.1E-121 T 14-10-2018 A4R43_15590 82117ce67b31531c7a502a3728a4f5a8 395 Pfam PF00107 Zinc-binding dehydrogenase 189 258 3.0E-12 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_15590 82117ce67b31531c7a502a3728a4f5a8 395 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 22 4.9E-13 T 14-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated A4R43_15590 82117ce67b31531c7a502a3728a4f5a8 395 SUPERFAMILY SSF50129 1 190 1.57E-55 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 Gene3D G3DSA:3.50.50.60 4 334 8.4E-122 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 256 271 2.1E-15 T 14-10-2018 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.1E-15 T 14-10-2018 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 325 2.1E-15 T 14-10-2018 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 128 143 2.1E-15 T 14-10-2018 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 287 2.1E-15 T 14-10-2018 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 SUPERFAMILY SSF51905 1 334 6.66E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 Gene3D G3DSA:3.20.20.70 388 673 1.1E-51 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 SUPERFAMILY SSF51395 387 668 2.2E-53 T 14-10-2018 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 Pfam PF01494 FAD binding domain 2 321 3.0E-16 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 413 666 4.7E-15 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4R43_37965 2bd8b3e20dfafe693db823819bc29d8b 675 Gene3D G3DSA:3.30.9.20 40 245 8.4E-122 T 14-10-2018 A4R43_36900 d060e5cb82cef585171a64476542d849 343 Gene3D G3DSA:3.40.50.720 117 305 5.9E-87 T 14-10-2018 A4R43_36900 d060e5cb82cef585171a64476542d849 343 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 245 261 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_36900 d060e5cb82cef585171a64476542d849 343 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 127 306 4.3E-54 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_36900 d060e5cb82cef585171a64476542d849 343 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 53 338 1.3E-18 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_36900 d060e5cb82cef585171a64476542d849 343 SUPERFAMILY SSF52283 50 138 1.17E-21 T 14-10-2018 A4R43_36900 d060e5cb82cef585171a64476542d849 343 Gene3D G3DSA:3.40.50.720 53 331 5.9E-87 T 14-10-2018 A4R43_36900 d060e5cb82cef585171a64476542d849 343 SUPERFAMILY SSF51735 121 306 1.51E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_33975 a85cb2872495f1bf422ce5314ac4cd0e 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 25.604 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33975 a85cb2872495f1bf422ce5314ac4cd0e 126 Gene3D G3DSA:1.10.8.50 1 72 2.4E-29 T 14-10-2018 A4R43_33975 a85cb2872495f1bf422ce5314ac4cd0e 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 7.4E-51 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33975 a85cb2872495f1bf422ce5314ac4cd0e 126 SUPERFAMILY SSF46946 2 122 1.13E-44 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4R43_33975 a85cb2872495f1bf422ce5314ac4cd0e 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 3.6E-32 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33975 a85cb2872495f1bf422ce5314ac4cd0e 126 Gene3D G3DSA:4.10.910.10 73 126 2.6E-24 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33975 a85cb2872495f1bf422ce5314ac4cd0e 126 PIRSF PIRSF002134 1 125 1.2E-42 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_18600 f2015c86db99bbdf30b0e9c42ab2107e 747 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 134 5.8E-29 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_18600 f2015c86db99bbdf30b0e9c42ab2107e 747 SUPERFAMILY SSF54665 14 154 3.01E-40 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4R43_18600 f2015c86db99bbdf30b0e9c42ab2107e 747 SMART SM01008 29 135 4.5E-44 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_18600 f2015c86db99bbdf30b0e9c42ab2107e 747 TIGRFAM TIGR03196 pucD: xanthine dehydrogenase D subunit 15 740 1.1E-242 T 14-10-2018 IPR017609 Xanthine dehydrogenase D subunit KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 A4R43_18600 f2015c86db99bbdf30b0e9c42ab2107e 747 SUPERFAMILY SSF56003 127 738 5.89E-153 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_18600 f2015c86db99bbdf30b0e9c42ab2107e 747 Gene3D G3DSA:3.30.365.10 2 745 1.5E-206 T 14-10-2018 A4R43_18600 f2015c86db99bbdf30b0e9c42ab2107e 747 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 153 683 4.1E-139 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_17015 26bf6343276d7879bd56b9aa4ded98e9 194 Gene3D G3DSA:3.40.630.30 8 185 1.5E-14 T 14-10-2018 A4R43_17015 26bf6343276d7879bd56b9aa4ded98e9 194 Pfam PF00583 Acetyltransferase (GNAT) family 25 162 1.4E-7 T 14-10-2018 IPR000182 GNAT domain A4R43_17015 26bf6343276d7879bd56b9aa4ded98e9 194 SUPERFAMILY SSF55729 24 174 6.56E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_12030 81135c7da0df03146cab95d8ced71166 265 Gene3D G3DSA:3.40.50.1820 2 258 9.5E-59 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12030 81135c7da0df03146cab95d8ced71166 265 Pfam PF12146 Serine aminopeptidase, S33 48 245 6.8E-20 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 A4R43_12030 81135c7da0df03146cab95d8ced71166 265 SUPERFAMILY SSF53474 7 258 6.95E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12030 81135c7da0df03146cab95d8ced71166 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12030 81135c7da0df03146cab95d8ced71166 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 2.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12030 81135c7da0df03146cab95d8ced71166 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 2.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12030 81135c7da0df03146cab95d8ced71166 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 2.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_15305 41218c131913576b56e07d25e2b6a2c4 341 Gene3D G3DSA:3.40.50.720 151 290 2.0E-103 T 14-10-2018 A4R43_15305 41218c131913576b56e07d25e2b6a2c4 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_15305 41218c131913576b56e07d25e2b6a2c4 341 SUPERFAMILY SSF51735 141 309 3.47E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15305 41218c131913576b56e07d25e2b6a2c4 341 SUPERFAMILY SSF50129 2 174 7.32E-50 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_15305 41218c131913576b56e07d25e2b6a2c4 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 135 5.3E-31 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_15305 41218c131913576b56e07d25e2b6a2c4 341 SMART SM00829 10 339 3.6E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_15305 41218c131913576b56e07d25e2b6a2c4 341 Gene3D G3DSA:3.90.180.10 13 333 2.0E-103 T 14-10-2018 A4R43_15305 41218c131913576b56e07d25e2b6a2c4 341 Pfam PF00107 Zinc-binding dehydrogenase 179 305 4.8E-20 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 Gene3D G3DSA:3.30.565.10 203 343 1.5E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 SUPERFAMILY SSF47384 115 198 8.83E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 SMART SM00388 132 198 1.2E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 SMART SM00304 78 131 2.7E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 SUPERFAMILY SSF55874 204 343 2.36E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 Pfam PF00672 HAMP domain 79 127 4.7E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 SUPERFAMILY SSF158472 79 127 1.11E-6 T 14-10-2018 A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 SMART SM00387 241 335 1.4E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 245 343 3.8E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 198 2.9E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_00350 a61eccb5b68e7bfac41c56ba7d91ef28 343 Gene3D G3DSA:1.10.287.130 82 198 2.0E-29 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-26 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.1E-26 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 1.1E-26 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 1.1E-26 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.1E-26 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 Gene3D G3DSA:3.50.50.60 3 335 2.3E-96 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 TIGRFAM TIGR02053 MerA: mercury(II) reductase 3 472 9.4E-175 T 14-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PIRSF PIRSF000350 1 473 4.8E-168 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 2.7E-59 T 14-10-2018 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 457 5.9E-26 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 Gene3D G3DSA:3.50.50.60 157 279 2.3E-96 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 Gene3D G3DSA:3.30.390.30 349 473 8.9E-40 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 SUPERFAMILY SSF55424 345 471 1.31E-32 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 SUPERFAMILY SSF51905 1 338 8.05E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02005 1cd2f0341bba90fb608e2dfc635b5f25 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 329 1.6E-59 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 340 413 6.6E-23 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 PIRSF PIRSF000478 6 428 1.6E-150 T 14-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 SUPERFAMILY SSF52418 78 321 7.46E-82 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 Gene3D G3DSA:3.40.1030.10 82 324 2.8E-136 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 115 130 - T 14-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 SMART SM00941 339 413 4.9E-32 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 Gene3D G3DSA:1.20.970.10 7 73 1.1E-22 T 14-10-2018 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 Pfam PF02885 Glycosyl transferase family, helical bundle domain 10 72 4.0E-17 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 SUPERFAMILY SSF54680 326 427 5.89E-27 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 Pfam PF00591 Glycosyl transferase family, a/b domain 82 293 6.1E-37 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 Gene3D G3DSA:3.90.1170.30 325 415 2.8E-136 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 SUPERFAMILY SSF47648 8 75 4.32E-20 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_34775 5ddfd09bdc0af60d25fe3db026f967a0 428 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 10 412 4.7E-165 T 14-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_25155 23cd48a3a1d0cd59c7279747467383fc 373 Gene3D G3DSA:3.30.565.10 249 371 1.2E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25155 23cd48a3a1d0cd59c7279747467383fc 373 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 369 3.5E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25155 23cd48a3a1d0cd59c7279747467383fc 373 SUPERFAMILY SSF55874 251 370 5.24E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_07070 96723c1630fece6d16610fb8b6839700 190 SUPERFAMILY SSF51182 63 184 1.07E-15 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_07070 96723c1630fece6d16610fb8b6839700 190 SUPERFAMILY SSF47413 10 74 4.79E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_07070 96723c1630fece6d16610fb8b6839700 190 SMART SM00530 15 70 2.9E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_07070 96723c1630fece6d16610fb8b6839700 190 Pfam PF07883 Cupin domain 127 175 1.2E-8 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_07070 96723c1630fece6d16610fb8b6839700 190 Gene3D G3DSA:2.60.120.10 104 188 8.8E-14 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_07070 96723c1630fece6d16610fb8b6839700 190 Gene3D G3DSA:1.10.260.40 1 74 9.2E-18 T 14-10-2018 A4R43_07070 96723c1630fece6d16610fb8b6839700 190 Pfam PF01381 Helix-turn-helix 16 70 1.7E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.40.50.1820 2907 3160 6.3E-67 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF52777 1041 1212 5.0E-28 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 ProSitePatterns PS00012 Phosphopantetheine attachment site. 991 1006 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF52777 1474 1650 5.89E-44 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:1.10.1200.10 953 1035 6.8E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SMART SM00823 Phosphopantetheine attachment site 967 1035 0.017 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SMART SM00823 Phosphopantetheine attachment site 2833 2890 0.0095 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF56801 429 980 2.62E-174 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2857 2872 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF52777 189 433 3.22E-54 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF00550 Phosphopantetheine attachment site 968 1029 5.5E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF00550 Phosphopantetheine attachment site 2836 2895 1.0E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF52777 11 188 9.78E-49 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF00975 Thioesterase domain 2918 3153 1.3E-29 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.40.50.150 2418 2602 2.1E-32 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SMART SM00824 Thioesterase 2920 3158 2.1E-4 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF53335 2409 2557 6.31E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF52777 1651 1900 2.22E-51 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF53474 2903 3157 5.46E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.40.50.12780 460 856 1.6E-149 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:1.10.1200.10 2821 2901 3.9E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.300.30 2316 2386 9.8E-11 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.300.30 857 952 1.7E-34 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1321 1459 1.8E-21 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 ProSitePatterns PS00455 Putative AMP-binding domain signature. 606 617 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF00501 AMP-binding enzyme 1932 2321 1.7E-106 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF00501 AMP-binding enzyme 470 864 2.0E-104 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.559.10 1474 1843 1.2E-131 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.559.30 190 446 4.1E-137 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 942 1.7E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1952 2345 3.7E-138 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 490 888 5.0E-138 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.300.30 2746 2820 1.5E-10 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF00668 Condensation domain 1469 1908 1.2E-84 T 14-10-2018 IPR001242 Condensation domain A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF00668 Condensation domain 1048 1430 1.8E-47 T 14-10-2018 IPR001242 Condensation domain A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF00668 Condensation domain 6 449 1.7E-88 T 14-10-2018 IPR001242 Condensation domain A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF56801 1894 2846 1.13E-160 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF47336 2825 2899 1.23E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2066 2077 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF52777 1201 1432 6.56E-33 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.559.10 11 381 4.1E-137 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.559.10 1036 1188 6.1E-34 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Pfam PF08242 Methyltransferase domain 2439 2536 1.2E-12 T 14-10-2018 IPR013217 Methyltransferase type 12 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.40.50.12780 1917 2315 1.3E-148 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.559.30 1652 1907 1.2E-131 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 Gene3D G3DSA:3.30.559.30 1189 1435 8.9E-56 T 14-10-2018 A4R43_38635 9e23ffaf077c12b7670c067a2b69f25b 3160 SUPERFAMILY SSF47336 960 1029 1.27E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_41005 50337986eed9c86e6e84b2bc739eb694 328 SUPERFAMILY SSF53098 134 320 1.09E-34 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_41005 50337986eed9c86e6e84b2bc739eb694 328 Pfam PF00665 Integrase core domain 133 279 6.8E-34 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_41005 50337986eed9c86e6e84b2bc739eb694 328 Pfam PF13011 leucine-zipper of insertion element IS481 2 82 5.7E-21 T 14-10-2018 IPR024967 DNA-binding domain, IS481-type A4R43_41005 50337986eed9c86e6e84b2bc739eb694 328 SUPERFAMILY SSF46689 2 111 1.79E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_41005 50337986eed9c86e6e84b2bc739eb694 328 Gene3D G3DSA:3.30.420.10 169 322 1.9E-25 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 SMART SM00420 6 58 3.2E-17 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 Gene3D G3DSA:1.10.10.10 1 55 3.3E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 SUPERFAMILY SSF100950 75 244 2.93E-27 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 Gene3D G3DSA:3.40.50.1360 72 238 2.4E-5 T 14-10-2018 A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 SUPERFAMILY SSF46785 4 64 2.0E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 Pfam PF00455 DeoR C terminal sensor domain 74 241 5.0E-46 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 SMART SM01134 72 242 1.1E-58 T 14-10-2018 A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.2E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.2E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_09125 93e4485ecf1078d5eb7dc515248488cc 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.0E-16 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_11105 80f01f879c716390c1a7358b3d2cf9f8 449 Pfam PF00877 NlpC/P60 family 325 441 3.4E-23 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_11105 80f01f879c716390c1a7358b3d2cf9f8 449 Gene3D G3DSA:3.90.1720.10 234 449 6.4E-52 T 14-10-2018 A4R43_11105 80f01f879c716390c1a7358b3d2cf9f8 449 SUPERFAMILY SSF56954 15 228 7.32E-5 T 14-10-2018 A4R43_11105 80f01f879c716390c1a7358b3d2cf9f8 449 SUPERFAMILY SSF54001 305 446 3.53E-30 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_11655 f4e55e17281df19eda8b6290e48a32c4 345 Pfam PF09594 Glycosyltransferase family 87 62 284 2.6E-40 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 14-10-2018 IPR018215 ClpP, Ser active site A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 Pfam PF00574 Clp protease 27 200 1.8E-73 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 Gene3D G3DSA:3.90.226.10 2 209 3.3E-76 T 14-10-2018 A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 4.7E-40 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 4.7E-40 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 4.7E-40 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 4.7E-40 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 4.7E-40 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 14-10-2018 IPR033135 ClpP, histidine active site A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 SUPERFAMILY SSF52096 20 205 1.37E-60 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_39050 978f6e7bd7dbd13be9c8bd2c2b4f0fec 209 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 38.291 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_17620 f785d0a86f47ecf3d68ca1ead9aad1ef 188 Pfam PF16859 Bacterial transcriptional repressor C-terminal 70 181 6.7E-31 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_17620 f785d0a86f47ecf3d68ca1ead9aad1ef 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.2E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17620 f785d0a86f47ecf3d68ca1ead9aad1ef 188 Gene3D G3DSA:1.10.10.60 4 51 5.1E-19 T 14-10-2018 A4R43_17620 f785d0a86f47ecf3d68ca1ead9aad1ef 188 SUPERFAMILY SSF48498 71 185 2.13E-25 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_17620 f785d0a86f47ecf3d68ca1ead9aad1ef 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.8E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17620 f785d0a86f47ecf3d68ca1ead9aad1ef 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.8E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17620 f785d0a86f47ecf3d68ca1ead9aad1ef 188 SUPERFAMILY SSF46689 4 61 3.12E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17620 f785d0a86f47ecf3d68ca1ead9aad1ef 188 Gene3D G3DSA:1.10.357.10 53 188 7.9E-34 T 14-10-2018 A4R43_10475 af267eb99972ed5ad0b6e5a278441864 185 SUPERFAMILY SSF46689 7 85 2.99E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_10475 af267eb99972ed5ad0b6e5a278441864 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 4.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_10475 af267eb99972ed5ad0b6e5a278441864 185 Gene3D G3DSA:1.10.357.10 7 185 7.1E-56 T 14-10-2018 A4R43_10475 af267eb99972ed5ad0b6e5a278441864 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_10475 af267eb99972ed5ad0b6e5a278441864 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_10475 af267eb99972ed5ad0b6e5a278441864 185 SUPERFAMILY SSF48498 96 181 8.9E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_05135 f32e0b0096845b50a38437e83cb283af 622 Pfam PF00664 ABC transporter transmembrane region 45 312 1.4E-39 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_05135 f32e0b0096845b50a38437e83cb283af 622 SUPERFAMILY SSF90123 27 347 5.1E-74 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_05135 f32e0b0096845b50a38437e83cb283af 622 Gene3D G3DSA:3.40.50.300 354 617 5.6E-86 T 14-10-2018 A4R43_05135 f32e0b0096845b50a38437e83cb283af 622 Gene3D G3DSA:1.20.1560.10 13 345 1.4E-79 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_05135 f32e0b0096845b50a38437e83cb283af 622 SMART SM00382 404 590 1.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05135 f32e0b0096845b50a38437e83cb283af 622 ProSitePatterns PS00211 ABC transporters family signature. 516 530 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_05135 f32e0b0096845b50a38437e83cb283af 622 SUPERFAMILY SSF52540 360 615 3.88E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05135 f32e0b0096845b50a38437e83cb283af 622 Pfam PF00005 ABC transporter 395 544 4.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 SUPERFAMILY SSF56349 107 296 1.27E-54 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 Gene3D G3DSA:1.10.443.10 111 292 2.8E-62 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 Pfam PF00589 Phage integrase family 113 282 1.7E-47 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 2 88 4.2E-18 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 SUPERFAMILY SSF47823 2 98 1.96E-15 T 14-10-2018 A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 4 298 9.2E-106 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 298 55.363 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 298 54.602 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD A4R43_14185 ae7f0473cd1253e8963a9f38f738aa08 300 Gene3D G3DSA:1.10.150.130 1 99 7.6E-18 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 SUPERFAMILY SSF52518 367 564 2.85E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 Gene3D G3DSA:3.40.50.1220 193 356 6.8E-46 T 14-10-2018 A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 Gene3D G3DSA:3.40.50.970 2 171 4.2E-65 T 14-10-2018 A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 329 1.9E-33 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 SUPERFAMILY SSF52518 3 184 5.58E-47 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 551 1.2E-32 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 2.1E-50 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 578 0.0 T 14-10-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 Gene3D G3DSA:3.40.50.970 357 580 1.8E-64 T 14-10-2018 A4R43_03475 cfba6d9fc124d399cd5c0160b31a23e2 587 SUPERFAMILY SSF52467 157 358 4.18E-45 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 PRINTS PR00412 Epoxide hydrolase signature 28 43 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 PRINTS PR00412 Epoxide hydrolase signature 73 86 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 PRINTS PR00412 Epoxide hydrolase signature 87 100 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 PRINTS PR00412 Epoxide hydrolase signature 8 26 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 Pfam PF12697 Alpha/beta hydrolase family 4 225 2.7E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 7.1E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 PRINTS PR00111 Alpha/beta hydrolase fold signature 28 43 7.1E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 86 7.1E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 Gene3D G3DSA:3.40.50.1820 1 233 3.1E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09305 80c8c630be9173e0f93d3eac0dcc81db 233 SUPERFAMILY SSF53474 3 230 4.4E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_24875 ac3d118d066b373cd9f98740e9207d0e 398 Gene3D G3DSA:3.40.50.150 181 386 1.7E-8 T 14-10-2018 A4R43_24875 ac3d118d066b373cd9f98740e9207d0e 398 Gene3D G3DSA:3.40.50.150 51 178 1.8E-22 T 14-10-2018 A4R43_24875 ac3d118d066b373cd9f98740e9207d0e 398 SUPERFAMILY SSF53335 103 278 8.8E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_24875 ac3d118d066b373cd9f98740e9207d0e 398 Pfam PF01555 DNA methylase 84 165 1.2E-14 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4R43_24875 ac3d118d066b373cd9f98740e9207d0e 398 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 150 170 5.0E-9 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_24875 ac3d118d066b373cd9f98740e9207d0e 398 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 127 145 5.0E-9 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_08145 b190a27d9e6c69998242499bc0230814 232 SUPERFAMILY SSF53681 123 206 3.53E-9 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_08145 b190a27d9e6c69998242499bc0230814 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 224 1.0E-29 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_08145 b190a27d9e6c69998242499bc0230814 232 Gene3D G3DSA:3.40.50.1860 2 223 4.3E-43 T 14-10-2018 A4R43_08145 b190a27d9e6c69998242499bc0230814 232 Gene3D G3DSA:3.40.50.1860 108 218 4.3E-43 T 14-10-2018 A4R43_08145 b190a27d9e6c69998242499bc0230814 232 SUPERFAMILY SSF53681 1 114 2.81E-17 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 210 505 6.5E-112 T 14-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 25 208 1.6E-61 T 14-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 22 506 9.1E-199 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 PIRSF PIRSF000110 9 507 3.2E-177 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 Gene3D G3DSA:3.30.360.10 197 506 5.8E-120 T 14-10-2018 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 SUPERFAMILY SSF51735 9 211 3.15E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 198 204 - T 14-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 Gene3D G3DSA:3.40.50.720 20 196 1.5E-54 T 14-10-2018 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 21 506 87.625 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 SUPERFAMILY SSF55347 198 505 5.89E-112 T 14-10-2018 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 188 216 3.0E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 347 373 3.0E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 258 274 3.0E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 177 3.0E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_04955 ac35d1dc42c81402470c9d0382201421 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 257 3.0E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 Gene3D G3DSA:3.40.50.720 2 249 6.5E-71 T 14-10-2018 A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 9.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 9.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.9E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 SUPERFAMILY SSF51735 7 246 2.14E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 8.3E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 8.3E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 8.3E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 8.3E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 8.3E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 8.3E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_29015 10cc0e10cd08ce5c964da061d7232206 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 244 1.3E-58 T 14-10-2018 A4R43_11805 8499e3cfea7c5dc1864a5b8eed7fd3c2 402 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 143 367 3.5E-30 T 14-10-2018 IPR024516 Mammalian cell entry, C-terminal A4R43_11805 8499e3cfea7c5dc1864a5b8eed7fd3c2 402 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 290 4.7E-43 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11805 8499e3cfea7c5dc1864a5b8eed7fd3c2 402 Pfam PF02470 MlaD protein 37 111 7.2E-9 T 14-10-2018 IPR003399 Mce/MlaD A4R43_07760 3c54d5cf37b43397b821f8d10b5d4b58 289 Pfam PF03466 LysR substrate binding domain 90 285 2.4E-29 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_07760 3c54d5cf37b43397b821f8d10b5d4b58 289 SUPERFAMILY SSF53850 91 285 5.1E-28 T 14-10-2018 A4R43_07760 3c54d5cf37b43397b821f8d10b5d4b58 289 Gene3D G3DSA:1.10.10.10 1 86 1.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07760 3c54d5cf37b43397b821f8d10b5d4b58 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.4E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_07760 3c54d5cf37b43397b821f8d10b5d4b58 289 Gene3D G3DSA:3.40.190.10 163 264 1.0E-30 T 14-10-2018 A4R43_07760 3c54d5cf37b43397b821f8d10b5d4b58 289 SUPERFAMILY SSF46785 3 83 5.76E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07760 3c54d5cf37b43397b821f8d10b5d4b58 289 Gene3D G3DSA:3.40.190.10 94 283 1.0E-30 T 14-10-2018 A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 Gene3D G3DSA:3.40.50.300 4 223 5.7E-62 T 14-10-2018 A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 SMART SM00382 30 213 1.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 SUPERFAMILY SSF52540 6 245 1.66E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 SUPERFAMILY SSF50331 238 357 7.78E-26 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 Gene3D G3DSA:2.40.50.140 284 341 8.5E-28 T 14-10-2018 A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 Pfam PF00005 ABC transporter 22 163 1.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 Pfam PF08402 TOBE domain 277 349 1.1E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A4R43_09105 c709f2dfbf5966ca0fc4ded3a5d753d6 359 Gene3D G3DSA:2.40.50.940 224 350 8.5E-28 T 14-10-2018 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 SUPERFAMILY SSF52540 242 443 1.5E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 80 1.1E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 Pfam PF00931 NB-ARC domain 266 443 6.2E-6 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 SUPERFAMILY SSF46894 4 82 2.47E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 Pfam PF03704 Bacterial transcriptional activator domain 96 233 9.6E-28 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 Gene3D G3DSA:1.25.40.10 95 241 1.8E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 PRINTS PR00364 Disease resistance protein signature 345 359 1.4E-8 T 14-10-2018 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 PRINTS PR00364 Disease resistance protein signature 426 440 1.4E-8 T 14-10-2018 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 PRINTS PR00364 Disease resistance protein signature 269 284 1.4E-8 T 14-10-2018 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 Gene3D G3DSA:1.10.10.10 1 91 4.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 SMART SM01043 96 237 3.8E-35 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 Gene3D G3DSA:3.40.50.300 242 389 5.6E-25 T 14-10-2018 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 SMART SM00862 16 89 5.3E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_12235 7b401878086d309fdf2d46dc28b96c96 559 SUPERFAMILY SSF48452 93 253 7.32E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 216 720 6.8E-86 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 SUPERFAMILY SSF81653 248 342 2.75E-26 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 SUPERFAMILY SSF56784 440 739 4.45E-54 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 SUPERFAMILY SSF55008 8 78 1.44E-18 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 Pfam PF00122 E1-E2 ATPase 245 420 2.4E-53 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 Gene3D G3DSA:3.30.70.100 10 80 5.6E-20 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 444 450 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 45 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 Pfam PF00702 haloacid dehalogenase-like hydrolase 438 653 2.6E-46 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 639 655 3.8E-8 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 611 627 3.8E-8 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 670 695 3.8E-8 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 Gene3D G3DSA:3.40.1110.10 453 571 5.0E-87 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 SUPERFAMILY SSF81665 191 714 3.27E-12 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 586 596 1.3E-23 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 292 306 1.3E-23 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 658 1.3E-23 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 674 1.3E-23 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 442 456 1.3E-23 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 Pfam PF00403 Heavy-metal-associated domain 15 73 2.9E-12 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 206 742 1.6E-152 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 161 741 1.9E-175 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 Gene3D G3DSA:2.70.150.20 235 347 3.5E-37 T 14-10-2018 A4R43_02900 4b7e5b5d269d2a6a38c7070606da4e01 751 Gene3D G3DSA:3.40.50.1000 423 691 5.0E-87 T 14-10-2018 IPR023214 HAD superfamily A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 Gene3D G3DSA:2.40.110.10 126 239 2.0E-45 T 14-10-2018 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 SUPERFAMILY SSF56645 9 246 3.27E-88 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 2.3E-28 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 Gene3D G3DSA:1.10.540.10 6 124 3.5E-35 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 PIRSF PIRSF016578 4 366 3.1E-15 T 14-10-2018 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 123 8.6E-32 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 SUPERFAMILY SSF47203 232 382 3.87E-49 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 381 5.0E-44 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_16245 eb607653ba0a76574c075f26c6ede8e5 382 Gene3D G3DSA:1.20.140.10 240 382 1.7E-44 T 14-10-2018 A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 Gene3D G3DSA:1.10.490.140 395 723 2.9E-127 T 14-10-2018 A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 388 713 1.7E-97 T 14-10-2018 IPR003776 YcaO-like domain A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 Gene3D G3DSA:3.30.160.660 542 665 2.9E-127 T 14-10-2018 A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 387 713 1.4E-27 T 14-10-2018 IPR003776 YcaO-like domain A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 SUPERFAMILY SSF69572 157 297 2.75E-10 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 Gene3D G3DSA:3.40.50.720 86 296 2.1E-48 T 14-10-2018 A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 Pfam PF00899 ThiF family 113 294 4.8E-7 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 388 749 1.6E-75 T 14-10-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 181 346 9.3E-43 T 14-10-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain A4R43_37025 c3b6dc1c5d9cf1553742c7867fd19b31 751 Gene3D G3DSA:2.40.50.820 417 505 2.9E-127 T 14-10-2018 A4R43_16095 6cfa37b0bad973e4c89cf4f0bc6a4234 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 210 4.0E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_16095 6cfa37b0bad973e4c89cf4f0bc6a4234 384 SUPERFAMILY SSF56645 3 241 8.64E-72 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16095 6cfa37b0bad973e4c89cf4f0bc6a4234 384 Gene3D G3DSA:2.40.110.10 121 231 7.8E-36 T 14-10-2018 A4R43_16095 6cfa37b0bad973e4c89cf4f0bc6a4234 384 SUPERFAMILY SSF47203 228 378 2.26E-18 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16095 6cfa37b0bad973e4c89cf4f0bc6a4234 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 375 2.8E-23 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16095 6cfa37b0bad973e4c89cf4f0bc6a4234 384 Gene3D G3DSA:1.10.540.10 2 117 2.5E-31 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16095 6cfa37b0bad973e4c89cf4f0bc6a4234 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.3E-23 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_16095 6cfa37b0bad973e4c89cf4f0bc6a4234 384 Gene3D G3DSA:1.20.140.10 232 383 1.8E-28 T 14-10-2018 A4R43_41250 d689b36deb0635de57680692df7a8656 137 SUPERFAMILY SSF53300 86 133 5.46E-6 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_41250 d689b36deb0635de57680692df7a8656 137 Gene3D G3DSA:3.40.50.410 44 133 6.7E-7 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 Gene3D G3DSA:2.40.10.10 246 334 6.0E-30 T 14-10-2018 A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 PIRSF PIRSF001134 2 347 1.5E-80 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 200 214 1.6E-30 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 293 316 1.6E-30 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 317 331 1.6E-30 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 253 273 1.6E-30 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 274 291 1.6E-30 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 SUPERFAMILY SSF50494 178 342 1.39E-25 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 Gene3D G3DSA:2.40.10.10 174 245 9.1E-25 T 14-10-2018 A4R43_00210 6fdc179f5835cda76301f7f955f29466 347 Pfam PF02983 Alpha-lytic protease prodomain 104 157 5.8E-9 T 14-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF55048 1680 1741 5.36E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1056 1303 9.7E-85 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF00550 Phosphopantetheine attachment site 2438 2504 7.1E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF00550 Phosphopantetheine attachment site 968 1033 2.4E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF51735 717 892 2.69E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF00501 AMP-binding enzyme 15 419 4.2E-104 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:3.40.50.720 716 937 4.9E-38 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:3.30.300.30 413 512 1.0E-26 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SMART SM01294 2437 2504 4.7E-5 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1563 1847 5.4E-119 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF00698 Acyl transferase domain 1563 1865 5.2E-53 T 14-10-2018 IPR014043 Acyl transferase A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:3.40.47.10 1051 1494 1.5E-181 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:1.10.1200.10 944 1037 2.0E-28 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:1.10.1200.10 2415 2509 7.7E-33 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:3.40.50.12780 4 412 7.8E-117 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF08659 KR domain 724 888 3.1E-29 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF08659 KR domain 2159 2332 1.8E-51 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1311 1426 2.2E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SMART SM00825 Beta-ketoacyl synthase 1058 1479 1.3E-210 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF51735 2159 2404 5.2E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1429 1518 1.1E-11 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF53901 1054 1424 1.84E-102 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 501 2.7E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:3.40.366.10 1561 1850 1.1E-149 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:3.30.70.3290 1495 1894 1.1E-149 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF52151 1560 1845 9.16E-75 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF47336 961 1071 1.96E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF51735 1952 2146 6.6E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF51735 522 709 1.26E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF56801 7 512 8.5E-153 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1216 1232 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:3.40.50.11460 523 709 3.7E-45 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2159 2333 1.4E-41 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 723 894 1.8E-17 T 14-10-2018 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SMART SM00823 Phosphopantetheine attachment site 2436 2508 2.1E-28 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SMART SM00823 Phosphopantetheine attachment site 965 1037 6.0E-25 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 SUPERFAMILY SSF47336 2430 2513 9.55E-19 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38500 46fb0e970470160f8bc1fbf7e89b4aea 2582 Gene3D G3DSA:3.40.50.720 1906 2407 8.1E-153 T 14-10-2018 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 458 570 4.5E-9 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 360 5.5E-12 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 213 5.5E-15 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1152 1167 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Gene3D G3DSA:3.30.300.30 1014 1114 1.3E-30 T 14-10-2018 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 SUPERFAMILY SSF56801 600 1111 1.18E-163 T 14-10-2018 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Gene3D G3DSA:1.10.540.10 7 115 9.9E-19 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 SUPERFAMILY SSF56645 29 238 1.3E-49 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 645 1044 2.0E-139 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 114 2.2E-14 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Pfam PF00550 Phosphopantetheine attachment site 1131 1190 6.9E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 SUPERFAMILY SSF47336 1130 1192 4.32E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 SMART SM00823 Phosphopantetheine attachment site 1128 1197 4.1E-8 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Gene3D G3DSA:1.20.140.10 454 575 8.0E-14 T 14-10-2018 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Gene3D G3DSA:1.20.140.10 231 364 8.2E-14 T 14-10-2018 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Gene3D G3DSA:3.40.50.12780 614 1012 6.0E-154 T 14-10-2018 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 ProSitePatterns PS00455 Putative AMP-binding domain signature. 763 774 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 SUPERFAMILY SSF47203 460 571 6.12E-16 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Pfam PF00501 AMP-binding enzyme 624 1020 8.6E-103 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 SUPERFAMILY SSF47203 227 361 2.09E-12 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Gene3D G3DSA:2.40.110.10 118 230 1.3E-26 T 14-10-2018 A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Pfam PF13193 AMP-binding enzyme C-terminal domain 1028 1103 5.4E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_12480 23feb16ef93e7a6645cbbec2205d253d 1198 Gene3D G3DSA:1.10.1200.10 1125 1198 7.2E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_03295 c6224e09c6a8a12ae0c621079a5bd2dc 297 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 22 256 1.1E-57 T 14-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted A4R43_03295 c6224e09c6a8a12ae0c621079a5bd2dc 297 Gene3D G3DSA:3.20.20.30 1 289 4.3E-63 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_03295 c6224e09c6a8a12ae0c621079a5bd2dc 297 SUPERFAMILY SSF51679 1 276 6.28E-53 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_03295 c6224e09c6a8a12ae0c621079a5bd2dc 297 Pfam PF00296 Luciferase-like monooxygenase 1 264 1.7E-44 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 4.7E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 4.7E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 Gene3D G3DSA:1.10.10.10 8 75 2.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 SMART SM00345 16 74 6.9E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 SUPERFAMILY SSF48008 80 203 3.66E-19 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 SUPERFAMILY SSF46785 6 78 6.82E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 Pfam PF07729 FCD domain 86 201 1.1E-17 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 8.7E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 SMART SM00895 84 205 3.4E-10 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_14380 3fb3ff9a4385cb5411e780b641e3b831 216 Gene3D G3DSA:1.20.120.530 77 209 1.5E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_17340 62bd833305013abddae18905cc3b50ca 155 Gene3D G3DSA:3.30.450.30 19 142 9.9E-42 T 14-10-2018 A4R43_17340 62bd833305013abddae18905cc3b50ca 155 SMART SM00960 21 111 1.5E-30 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_17340 62bd833305013abddae18905cc3b50ca 155 Pfam PF03259 Roadblock/LC7 domain 21 110 5.8E-25 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_17340 62bd833305013abddae18905cc3b50ca 155 SUPERFAMILY SSF103196 20 138 1.26E-32 T 14-10-2018 A4R43_08765 ad112f4e5915121d4df888585631d674 114 Pfam PF03795 YCII-related domain 19 100 2.3E-13 T 14-10-2018 IPR005545 YCII-related A4R43_08765 ad112f4e5915121d4df888585631d674 114 Gene3D G3DSA:3.30.70.1060 1 114 4.3E-34 T 14-10-2018 A4R43_08765 ad112f4e5915121d4df888585631d674 114 SUPERFAMILY SSF54909 10 112 9.12E-28 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_09745 b7e01c79ad3407a35d890bb68537f22f 915 SUPERFAMILY SSF49899 155 327 1.4E-30 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_09745 b7e01c79ad3407a35d890bb68537f22f 915 SUPERFAMILY SSF48208 393 610 3.45E-12 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_09745 b7e01c79ad3407a35d890bb68537f22f 915 Gene3D G3DSA:2.60.120.200 168 364 6.7E-32 T 14-10-2018 A4R43_09745 b7e01c79ad3407a35d890bb68537f22f 915 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 47 144 2.9E-9 T 14-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 A4R43_09745 b7e01c79ad3407a35d890bb68537f22f 915 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 371 781 2.8E-95 T 14-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 A4R43_09745 b7e01c79ad3407a35d890bb68537f22f 915 SMART SM00560 186 322 4.9E-4 T 14-10-2018 IPR006558 LamG-like jellyroll fold A4R43_09745 b7e01c79ad3407a35d890bb68537f22f 915 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 170 325 1.7E-33 T 14-10-2018 A4R43_10785 835e07405a2f6212cb6e7a84c993c163 500 PIRSF PIRSF018077 8 496 4.7E-204 T 14-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 A4R43_10785 835e07405a2f6212cb6e7a84c993c163 500 Pfam PF03136 Pup-ligase protein 3 454 1.4E-179 T 14-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 A4R43_10785 835e07405a2f6212cb6e7a84c993c163 500 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 485 5.2E-231 T 14-10-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 A4R43_36930 3f932c56ee07676e2847bcb6b9559765 129 Pfam PF07883 Cupin domain 40 96 4.6E-12 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_36930 3f932c56ee07676e2847bcb6b9559765 129 Gene3D G3DSA:2.60.120.10 2 108 4.8E-33 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_36930 3f932c56ee07676e2847bcb6b9559765 129 SUPERFAMILY SSF51182 3 111 3.12E-23 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 126 333 1.1E-77 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 Gene3D G3DSA:2.40.50.100 523 598 1.2E-21 T 14-10-2018 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 SUPERFAMILY SSF52440 11 124 9.35E-46 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 Pfam PF00289 Biotin carboxylase, N-terminal domain 13 121 1.6E-42 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 Pfam PF00364 Biotin-requiring enzyme 531 597 1.2E-17 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 Pfam PF02785 Biotin carboxylase C-terminal domain 346 456 1.8E-35 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 SUPERFAMILY SSF51230 527 597 1.24E-20 T 14-10-2018 IPR011053 Single hybrid motif A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 Gene3D G3DSA:3.30.470.130 3 462 1.6E-177 T 14-10-2018 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 SMART SM00878 346 456 5.5E-56 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 554 571 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 SUPERFAMILY SSF51246 340 460 3.82E-37 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_35050 17e7a27a480cd1b74766a98750b1bdf8 599 SUPERFAMILY SSF56059 126 335 6.72E-59 T 14-10-2018 A4R43_14195 561f6a1dde0aeca282cfde595ce638ed 361 SUPERFAMILY SSF53098 201 341 1.25E-5 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_14195 561f6a1dde0aeca282cfde595ce638ed 361 SUPERFAMILY SSF46689 25 136 2.69E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14195 561f6a1dde0aeca282cfde595ce638ed 361 Pfam PF13358 DDE superfamily endonuclease 173 318 1.1E-23 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain A4R43_14195 561f6a1dde0aeca282cfde595ce638ed 361 Pfam PF13551 Winged helix-turn helix 35 95 6.6E-15 T 14-10-2018 A4R43_18010 561f6a1dde0aeca282cfde595ce638ed 361 SUPERFAMILY SSF53098 201 341 1.25E-5 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_18010 561f6a1dde0aeca282cfde595ce638ed 361 SUPERFAMILY SSF46689 25 136 2.69E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_18010 561f6a1dde0aeca282cfde595ce638ed 361 Pfam PF13358 DDE superfamily endonuclease 173 318 1.1E-23 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain A4R43_18010 561f6a1dde0aeca282cfde595ce638ed 361 Pfam PF13551 Winged helix-turn helix 35 95 6.6E-15 T 14-10-2018 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 SUPERFAMILY SSF53474 417 671 1.95E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 7 392 3.8E-31 T 14-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 472 496 1.9E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 500 519 1.9E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 550 1.9E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 604 626 1.9E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 445 463 1.9E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 585 600 1.9E-47 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 Gene3D G3DSA:3.40.50.1820 6 632 2.1E-142 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 Pfam PF00326 Prolyl oligopeptidase family 468 671 1.3E-51 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 SUPERFAMILY SSF50993 7 393 8.63E-56 T 14-10-2018 A4R43_16750 0ebd962d549952d7b111fe482ca6cbda 675 Gene3D G3DSA:2.130.10.120 56 408 2.1E-142 T 14-10-2018 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 110 201 1.9E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 Gene3D G3DSA:1.10.540.10 6 108 3.2E-13 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 Gene3D G3DSA:2.40.110.10 109 218 3.0E-36 T 14-10-2018 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 Gene3D G3DSA:1.20.140.10 219 365 6.4E-45 T 14-10-2018 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 PIRSF PIRSF016578 2 78 14.0 T 14-10-2018 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 PIRSF PIRSF016578 195 367 3.8E-12 T 14-10-2018 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 PIRSF PIRSF016578 117 178 0.041 T 14-10-2018 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 112 124 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 SUPERFAMILY SSF56645 19 224 2.23E-53 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 213 362 6.5E-45 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 SUPERFAMILY SSF47203 212 365 1.56E-47 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_37935 6a4239528f98e9bdc55ba56ff96dfbcd 367 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 106 8.6E-8 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_33550 3c1716c890fef360207e6011b72f2fc0 137 Gene3D G3DSA:1.20.5.1030 77 134 1.1E-18 T 14-10-2018 IPR038379 SecE superfamily A4R43_33550 3c1716c890fef360207e6011b72f2fc0 137 Hamap MF_00422 Protein translocase subunit SecE [secE]. 78 133 13.076 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_33550 3c1716c890fef360207e6011b72f2fc0 137 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 81 136 4.2E-20 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 A4R43_33550 3c1716c890fef360207e6011b72f2fc0 137 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 82 132 3.9E-19 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_33550 3c1716c890fef360207e6011b72f2fc0 137 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 83 111 - T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_09135 485b750619625ff42e1c541850cf9dcd 301 PIRSF PIRSF000535 1 294 6.3E-74 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A4R43_09135 485b750619625ff42e1c541850cf9dcd 301 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 291 2.7E-81 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A4R43_09135 485b750619625ff42e1c541850cf9dcd 301 Pfam PF00294 pfkB family carbohydrate kinase 17 273 6.6E-43 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_09135 485b750619625ff42e1c541850cf9dcd 301 Gene3D G3DSA:3.40.1190.20 1 300 4.6E-98 T 14-10-2018 IPR029056 Ribokinase-like A4R43_09135 485b750619625ff42e1c541850cf9dcd 301 SUPERFAMILY SSF53613 2 271 9.04E-58 T 14-10-2018 IPR029056 Ribokinase-like A4R43_09135 485b750619625ff42e1c541850cf9dcd 301 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 234 247 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_09135 485b750619625ff42e1c541850cf9dcd 301 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_00955 224890a245d25f3fe3acfef9a3664bca 301 SUPERFAMILY SSF46785 82 186 4.34E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00955 224890a245d25f3fe3acfef9a3664bca 301 Gene3D G3DSA:1.10.10.10 75 163 2.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00955 224890a245d25f3fe3acfef9a3664bca 301 Pfam PF13936 Helix-turn-helix domain 5 45 8.5E-16 T 14-10-2018 IPR025246 Transposase IS30-like HTH domain A4R43_00955 224890a245d25f3fe3acfef9a3664bca 301 Gene3D G3DSA:1.10.10.10 229 264 6.9E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00550 023dcda5ece6b54c88f609d9df892ea9 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00550 023dcda5ece6b54c88f609d9df892ea9 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00550 023dcda5ece6b54c88f609d9df892ea9 220 Gene3D G3DSA:1.10.357.10 9 217 3.7E-28 T 14-10-2018 A4R43_00550 023dcda5ece6b54c88f609d9df892ea9 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 84 2.8E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00550 023dcda5ece6b54c88f609d9df892ea9 220 SUPERFAMILY SSF46689 32 96 5.99E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 SUPERFAMILY SSF53223 86 235 1.15E-55 T 14-10-2018 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 SUPERFAMILY SSF51735 237 458 5.4E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 Gene3D G3DSA:3.40.50.720 235 460 2.6E-70 T 14-10-2018 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 Pfam PF00390 Malic enzyme, N-terminal domain 93 189 2.5E-23 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 PIRSF PIRSF000106 28 460 9.4E-77 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 Pfam PF03949 Malic enzyme, NAD binding domain 239 457 5.2E-22 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 SMART SM01274 92 225 8.4E-84 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 SMART SM00919 237 459 7.1E-103 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 Gene3D G3DSA:3.40.50.10380 76 234 2.8E-70 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 PRINTS PR00072 Malic enzyme signature 154 176 5.9E-7 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 PRINTS PR00072 Malic enzyme signature 233 249 5.9E-7 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4R43_25940 026c4563c2a19137aa991f11d41a8923 460 PRINTS PR00072 Malic enzyme signature 264 280 5.9E-7 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4R43_19415 de32bc2274aba51d72d2a5ce9a865bca 102 Gene3D G3DSA:2.60.300.12 2 99 5.9E-11 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A4R43_19415 de32bc2274aba51d72d2a5ce9a865bca 102 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 86 3.0E-6 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A4R43_19415 de32bc2274aba51d72d2a5ce9a865bca 102 SUPERFAMILY SSF89360 1 86 3.92E-11 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 312 27.9 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 Gene3D G3DSA:3.30.470.20 90 303 1.0E-53 T 14-10-2018 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 SUPERFAMILY SSF56059 98 307 2.47E-43 T 14-10-2018 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 Gene3D G3DSA:3.30.1490.20 112 185 1.0E-53 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 Pfam PF01820 D-ala D-ala ligase N-terminus 6 86 2.3E-13 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 SUPERFAMILY SSF52440 4 97 1.15E-21 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 Gene3D G3DSA:3.40.50.20 1 85 7.0E-23 T 14-10-2018 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 Pfam PF07478 D-ala D-ala ligase C-terminus 104 308 2.1E-41 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 PIRSF PIRSF039102 39 314 2.4E-63 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_30465 4cc3a7219b1b53cbc867105a8007f9f4 314 PIRSF PIRSF039102 2 45 5.8E-7 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 Gene3D G3DSA:1.50.10.10 322 683 9.9E-120 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 PIRSF PIRSF036289 5 761 1.3E-209 T 14-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 19 271 6.6E-64 T 14-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 701 751 2.5E-15 T 14-10-2018 IPR005194 Glycoside hydrolase family 65, C-terminal A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 SUPERFAMILY SSF74650 10 273 5.96E-61 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 SUPERFAMILY SSF48208 280 750 1.02E-118 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 Gene3D G3DSA:2.70.98.40 7 273 3.0E-59 T 14-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 Gene3D G3DSA:2.60.420.10 684 754 3.5E-19 T 14-10-2018 A4R43_41450 97ec9bcaec4330ffb108dc0fcaf57f8a 783 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 328 697 8.6E-127 T 14-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 A4R43_41235 85ec0ed596dfb59f0aee8aaeede493c9 506 Gene3D G3DSA:1.10.510.10 106 289 5.6E-44 T 14-10-2018 A4R43_41235 85ec0ed596dfb59f0aee8aaeede493c9 506 SUPERFAMILY SSF56112 16 297 6.47E-71 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_41235 85ec0ed596dfb59f0aee8aaeede493c9 506 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 144 156 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_41235 85ec0ed596dfb59f0aee8aaeede493c9 506 Pfam PF00069 Protein kinase domain 23 271 2.9E-49 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_41235 85ec0ed596dfb59f0aee8aaeede493c9 506 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 29 52 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_41235 85ec0ed596dfb59f0aee8aaeede493c9 506 SMART SM00220 23 277 5.8E-61 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_41235 85ec0ed596dfb59f0aee8aaeede493c9 506 Pfam PF13845 Septum formation 379 473 9.4E-7 T 14-10-2018 IPR026004 Septum formation-related domain A4R43_41235 85ec0ed596dfb59f0aee8aaeede493c9 506 Gene3D G3DSA:3.30.200.20 15 104 2.3E-25 T 14-10-2018 A4R43_13155 5bfc1c14241c4826fc7a8b04424469e9 213 SMART SM00346 12 91 3.8E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_13155 5bfc1c14241c4826fc7a8b04424469e9 213 Pfam PF09339 IclR helix-turn-helix domain 15 62 3.6E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_13155 5bfc1c14241c4826fc7a8b04424469e9 213 SUPERFAMILY SSF46785 12 78 5.4E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13155 5bfc1c14241c4826fc7a8b04424469e9 213 SUPERFAMILY SSF55781 77 212 4.71E-22 T 14-10-2018 A4R43_13155 5bfc1c14241c4826fc7a8b04424469e9 213 Gene3D G3DSA:3.30.450.40 151 213 2.7E-7 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_13155 5bfc1c14241c4826fc7a8b04424469e9 213 Gene3D G3DSA:3.30.450.40 80 150 7.3E-16 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_13155 5bfc1c14241c4826fc7a8b04424469e9 213 Gene3D G3DSA:1.10.10.10 10 79 1.8E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04700 dd2b6ea3b6bb85de7b5b3c744e18b383 150 SUPERFAMILY SSF48013 15 139 6.02E-37 T 14-10-2018 IPR035926 NusB-like superfamily A4R43_04700 dd2b6ea3b6bb85de7b5b3c744e18b383 150 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 15 139 1.8E-37 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 A4R43_04700 dd2b6ea3b6bb85de7b5b3c744e18b383 150 Gene3D G3DSA:1.10.940.10 10 139 1.0E-40 T 14-10-2018 IPR035926 NusB-like superfamily A4R43_04700 dd2b6ea3b6bb85de7b5b3c744e18b383 150 Pfam PF01029 NusB family 17 139 2.0E-33 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4R43_04700 dd2b6ea3b6bb85de7b5b3c744e18b383 150 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 13 144 22.122 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 527 904 3.7E-124 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 ProSitePatterns PS00455 Putative AMP-binding domain signature. 630 641 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Pfam PF00501 AMP-binding enzyme 507 880 1.2E-91 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Gene3D G3DSA:3.40.50.12780 498 872 1.7E-130 T 14-10-2018 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Pfam PF00550 Phosphopantetheine attachment site 990 1052 7.7E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Pfam PF13193 AMP-binding enzyme C-terminal domain 888 962 2.9E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Gene3D G3DSA:1.10.1200.10 977 1057 3.4E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Gene3D G3DSA:3.30.559.30 222 470 5.3E-129 T 14-10-2018 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Pfam PF00975 Thioesterase domain 1075 1315 4.4E-23 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Gene3D G3DSA:3.40.50.1820 1063 1323 9.6E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 SUPERFAMILY SSF53474 1054 1319 8.02E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 SUPERFAMILY SSF47336 979 1053 3.27E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 SMART SM00824 Thioesterase 1079 1319 2.5E-5 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 SMART SM00823 Phosphopantetheine attachment site 987 1056 4.7E-9 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Gene3D G3DSA:3.30.559.10 46 412 5.3E-129 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 SUPERFAMILY SSF52777 226 492 8.89E-59 T 14-10-2018 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 SUPERFAMILY SSF52777 47 218 1.22E-41 T 14-10-2018 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Gene3D G3DSA:3.30.300.30 874 976 3.2E-34 T 14-10-2018 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 SUPERFAMILY SSF56801 467 1000 9.55E-154 T 14-10-2018 A4R43_08325 545cd32bff192d8cd732fea0668b4048 1325 Pfam PF00668 Condensation domain 43 482 4.9E-89 T 14-10-2018 IPR001242 Condensation domain A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 292 1.2E-120 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 SUPERFAMILY SSF51735 1 128 1.05E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 38.491 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 Gene3D G3DSA:3.40.50.261 130 293 9.0E-59 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 PIRSF PIRSF001553 1 295 1.2E-112 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 SMART SM00881 4 104 2.8E-30 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 Gene3D G3DSA:3.40.50.720 1 129 4.2E-44 T 14-10-2018 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 Pfam PF00549 CoA-ligase 158 275 4.2E-14 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 9.6E-34 T 14-10-2018 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 9.6E-34 T 14-10-2018 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 9.6E-34 T 14-10-2018 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 9.6E-34 T 14-10-2018 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 Pfam PF02629 CoA binding domain 7 103 9.9E-23 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_05765 de14f9aef00f0d738c0ebf4cd0d2ddfa 295 SUPERFAMILY SSF52210 129 291 2.09E-43 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_08810 0dd4afb1a38db5aac23ddd509d33d618 166 SUPERFAMILY SSF54593 18 161 7.25E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_08810 0dd4afb1a38db5aac23ddd509d33d618 166 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 22 127 3.0E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_08810 0dd4afb1a38db5aac23ddd509d33d618 166 Gene3D G3DSA:3.30.720.110 80 145 3.4E-18 T 14-10-2018 A4R43_08810 0dd4afb1a38db5aac23ddd509d33d618 166 Gene3D G3DSA:3.30.720.120 16 79 2.5E-5 T 14-10-2018 A4R43_32245 b2c9168d8158cfa780bef1a536c741da 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 3.1E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32245 b2c9168d8158cfa780bef1a536c741da 213 SUPERFAMILY SSF48498 79 202 1.17E-29 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_32245 b2c9168d8158cfa780bef1a536c741da 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32245 b2c9168d8158cfa780bef1a536c741da 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32245 b2c9168d8158cfa780bef1a536c741da 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_32245 b2c9168d8158cfa780bef1a536c741da 213 Gene3D G3DSA:1.10.357.10 2 211 4.9E-55 T 14-10-2018 A4R43_32245 b2c9168d8158cfa780bef1a536c741da 213 SUPERFAMILY SSF46689 2 70 1.64E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.30 3059 3326 8.5E-126 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF56801 3320 3878 1.31E-151 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3889 3904 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 880 1280 3.4E-127 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3385 3785 4.1E-127 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2327 2727 3.5E-126 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF47336 3858 3927 3.27E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1708 1843 2.4E-21 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 4217 4360 9.0E-24 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.10 2890 3271 8.5E-126 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF47336 1353 1422 2.88E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.30 1579 1823 8.0E-55 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.30 4087 4344 6.5E-56 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF56801 2262 2821 2.75E-152 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.30 554 822 2.2E-127 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 1434 1583 7.34E-30 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 3939 4091 2.11E-26 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.10 387 750 2.2E-127 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.30 2024 2280 3.7E-130 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 387 550 2.67E-36 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 4098 4340 6.78E-34 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.300.30 1251 1353 9.8E-31 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.300.30 3756 3858 1.7E-29 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:1.10.1200.10 1354 1424 1.2E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:1.10.1200.10 3859 3929 3.9E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.40.50.12780 3355 3754 1.2E-123 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.40.50.12780 850 1249 1.6E-123 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.40.50.12780 2297 2696 9.9E-126 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00501 AMP-binding enzyme 863 1257 8.1E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00501 AMP-binding enzyme 2308 2704 7.4E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00501 AMP-binding enzyme 3366 3762 1.0E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.10 1855 2215 3.7E-130 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 2023 2290 6.45E-53 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SMART SM00826 2 151 6.8E-4 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 561 843 1.33E-61 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SMART SM00823 Phosphopantetheine attachment site 1360 1428 8.8E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SMART SM00823 Phosphopantetheine attachment site 3865 3933 0.0054 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SMART SM00823 Phosphopantetheine attachment site 293 365 8.1E-12 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SMART SM00823 Phosphopantetheine attachment site 2808 2876 4.3E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00668 Condensation domain 2890 3341 2.0E-81 T 14-10-2018 IPR001242 Condensation domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00668 Condensation domain 389 837 2.3E-80 T 14-10-2018 IPR001242 Condensation domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00668 Condensation domain 1850 2283 6.7E-93 T 14-10-2018 IPR001242 Condensation domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00668 Condensation domain 1442 1819 5.9E-48 T 14-10-2018 IPR001242 Condensation domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00668 Condensation domain 3947 4343 1.3E-52 T 14-10-2018 IPR001242 Condensation domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3501 3512 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF56801 816 1373 1.03E-150 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF13193 AMP-binding enzyme C-terminal domain 3770 3840 2.5E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF13193 AMP-binding enzyme C-terminal domain 2712 2783 1.7E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF13193 AMP-binding enzyme C-terminal domain 1265 1335 1.3E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2832 2847 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:1.10.1200.10 2795 2881 9.7E-25 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 2890 3055 7.89E-37 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.10 3933 4086 6.6E-35 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.559.10 1428 1578 2.3E-36 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 3065 3348 5.23E-61 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF14765 Polyketide synthase dehydratase 6 268 3.4E-33 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF47336 2801 2872 6.81E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.10.129.110 2 268 3.4E-40 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:3.30.300.30 2697 2794 4.5E-31 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2443 2454 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1384 1399 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Gene3D G3DSA:1.10.1200.10 280 366 1.6E-13 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00550 Phosphopantetheine attachment site 3867 3927 4.3E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00550 Phosphopantetheine attachment site 1362 1422 3.1E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00550 Phosphopantetheine attachment site 2810 2872 3.3E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 Pfam PF00550 Phosphopantetheine attachment site 301 359 1.3E-7 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 1855 2022 1.41E-45 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 ProSitePatterns PS00455 Putative AMP-binding domain signature. 996 1007 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF52777 1591 1821 1.45E-32 T 14-10-2018 A4R43_38630 101206075d234bc01a0c19de4630ceba 4370 SUPERFAMILY SSF47336 290 370 6.94E-12 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_13370 296b8acda81a8f1f442f2676610147c5 429 Gene3D G3DSA:1.20.1250.20 17 429 8.9E-65 T 14-10-2018 A4R43_13370 296b8acda81a8f1f442f2676610147c5 429 Pfam PF07690 Major Facilitator Superfamily 31 373 3.8E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_13370 296b8acda81a8f1f442f2676610147c5 429 SUPERFAMILY SSF103473 15 424 8.76E-63 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_13370 296b8acda81a8f1f442f2676610147c5 429 ProSitePatterns PS00216 Sugar transport proteins signature 1. 298 315 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_13370 296b8acda81a8f1f442f2676610147c5 429 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_26425 5585971dcbb50ef7d0b059e5ba5950a9 619 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 555 615 5.1E-10 T 14-10-2018 IPR001607 Zinc finger, UBP-type GO:0008270 A4R43_26425 5585971dcbb50ef7d0b059e5ba5950a9 619 Gene3D G3DSA:3.30.40.10 533 618 2.4E-27 T 14-10-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type A4R43_26425 5585971dcbb50ef7d0b059e5ba5950a9 619 Pfam PF00999 Sodium/hydrogen exchanger family 10 395 1.0E-57 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4R43_26425 5585971dcbb50ef7d0b059e5ba5950a9 619 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 514 4.1E-95 T 14-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 A4R43_26425 5585971dcbb50ef7d0b059e5ba5950a9 619 SUPERFAMILY SSF57850 536 616 1.77E-23 T 14-10-2018 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 4.2E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 SUPERFAMILY SSF46894 144 213 1.87E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 Gene3D G3DSA:3.40.50.12740 3 213 6.9E-65 T 14-10-2018 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 SMART SM00448 3 116 5.5E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 Pfam PF00072 Response regulator receiver domain 5 116 6.0E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10545 c373bbe3faddcf5820f746605e659786 215 SUPERFAMILY SSF52172 2 126 7.12E-33 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_10545 c373bbe3faddcf5820f746605e659786 215 SMART SM00421 150 207 1.9E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 Pfam PF01467 Cytidylyltransferase-like 330 422 4.6E-18 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 SUPERFAMILY SSF53613 6 288 3.27E-33 T 14-10-2018 IPR029056 Ribokinase-like A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 Gene3D G3DSA:3.40.50.620 305 455 8.5E-35 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 Gene3D G3DSA:3.40.1190.20 1 298 8.0E-68 T 14-10-2018 IPR029056 Ribokinase-like A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 SUPERFAMILY SSF52374 327 453 3.38E-22 T 14-10-2018 A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 316 455 5.0E-56 T 14-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 328 392 3.4E-16 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_07525 d9df8bff3f11e11e357eaa7e9ca4994a 455 Pfam PF00294 pfkB family carbohydrate kinase 6 294 6.4E-23 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 122 133 - T 14-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 ProSitePatterns PS00106 Galactokinase signature. 27 38 - T 14-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 SUPERFAMILY SSF55060 212 386 4.32E-44 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 Pfam PF08544 GHMP kinases C terminal 289 367 2.9E-12 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 Gene3D G3DSA:3.30.70.890 207 363 4.0E-119 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PRINTS PR00959 Mevalonate kinase family signature 334 351 8.3E-41 T 14-10-2018 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PRINTS PR00959 Mevalonate kinase family signature 167 186 8.3E-41 T 14-10-2018 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PRINTS PR00959 Mevalonate kinase family signature 120 142 8.3E-41 T 14-10-2018 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PRINTS PR00959 Mevalonate kinase family signature 25 49 8.3E-41 T 14-10-2018 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PIRSF PIRSF000530 2 388 1.4E-112 T 14-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 Pfam PF00288 GHMP kinases N terminal domain 115 184 5.9E-14 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 Pfam PF10509 Galactokinase galactose-binding signature 10 58 4.2E-21 T 14-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 Gene3D G3DSA:3.30.230.10 20 206 4.0E-119 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PRINTS PR00473 Galactokinase signature 94 105 7.6E-25 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PRINTS PR00473 Galactokinase signature 113 131 7.6E-25 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PRINTS PR00473 Galactokinase signature 271 285 7.6E-25 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 PRINTS PR00473 Galactokinase signature 27 45 7.6E-25 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 SUPERFAMILY SSF54211 5 207 1.04E-53 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_16690 6c87cd8f43e005ad5d6f2717f23b1296 395 TIGRFAM TIGR00131 gal_kin: galactokinase 8 387 2.3E-83 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4R43_25545 9d8bc4927cfbaac51236769da7dd0146 200 SUPERFAMILY SSF48498 93 199 2.22E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_25545 9d8bc4927cfbaac51236769da7dd0146 200 Gene3D G3DSA:1.10.357.10 64 199 1.5E-11 T 14-10-2018 A4R43_25545 9d8bc4927cfbaac51236769da7dd0146 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 65 7.8E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25545 9d8bc4927cfbaac51236769da7dd0146 200 Gene3D G3DSA:1.10.10.60 2 63 1.5E-10 T 14-10-2018 A4R43_25545 9d8bc4927cfbaac51236769da7dd0146 200 SUPERFAMILY SSF46689 9 93 1.69E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14205 b8a986047bfa53768c7ce9214a161861 567 Pfam PF00117 Glutamine amidotransferase class-I 312 543 5.7E-49 T 14-10-2018 IPR017926 Glutamine amidotransferase A4R43_14205 b8a986047bfa53768c7ce9214a161861 567 TIGRFAM TIGR00337 PyrG: CTP synthase 7 544 7.2E-231 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4R43_14205 b8a986047bfa53768c7ce9214a161861 567 Gene3D G3DSA:3.40.50.880 297 551 1.0E-99 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_14205 b8a986047bfa53768c7ce9214a161861 567 SUPERFAMILY SSF52317 300 549 2.6E-75 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_14205 b8a986047bfa53768c7ce9214a161861 567 Pfam PF06418 CTP synthase N-terminus 9 277 4.1E-122 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4R43_14205 b8a986047bfa53768c7ce9214a161861 567 Hamap MF_01227 CTP synthase [pyrG]. 8 549 50.139 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4R43_14205 b8a986047bfa53768c7ce9214a161861 567 Gene3D G3DSA:3.40.50.300 2 296 2.1E-133 T 14-10-2018 A4R43_14205 b8a986047bfa53768c7ce9214a161861 567 SUPERFAMILY SSF52540 8 277 7.36E-119 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34405 0e780b2183f5fd23bb063f64994bc8f9 302 Pfam PF03466 LysR substrate binding domain 88 293 2.3E-36 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_34405 0e780b2183f5fd23bb063f64994bc8f9 302 SUPERFAMILY SSF53850 89 294 7.41E-34 T 14-10-2018 A4R43_34405 0e780b2183f5fd23bb063f64994bc8f9 302 Gene3D G3DSA:1.10.10.10 1 91 6.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34405 0e780b2183f5fd23bb063f64994bc8f9 302 Gene3D G3DSA:3.40.190.10 92 274 5.6E-42 T 14-10-2018 A4R43_34405 0e780b2183f5fd23bb063f64994bc8f9 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.0E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_34405 0e780b2183f5fd23bb063f64994bc8f9 302 Gene3D G3DSA:3.40.190.10 168 269 5.6E-42 T 14-10-2018 A4R43_34405 0e780b2183f5fd23bb063f64994bc8f9 302 SUPERFAMILY SSF46785 1 111 1.76E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Gene3D G3DSA:1.10.1200.10 990 1079 1.4E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 SUPERFAMILY SSF52777 214 455 3.56E-35 T 14-10-2018 A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Gene3D G3DSA:3.30.559.10 27 205 1.0E-48 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Gene3D G3DSA:3.30.300.30 886 989 2.2E-33 T 14-10-2018 A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Pfam PF13193 AMP-binding enzyme C-terminal domain 900 975 6.0E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Gene3D G3DSA:3.30.559.30 213 462 9.7E-77 T 14-10-2018 A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 513 916 1.4E-123 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Pfam PF00668 Condensation domain 60 370 8.5E-19 T 14-10-2018 IPR001242 Condensation domain A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1026 1041 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 SUPERFAMILY SSF47336 996 1072 1.31E-13 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Gene3D G3DSA:3.40.50.12780 484 884 1.0E-119 T 14-10-2018 A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 ProSitePatterns PS00455 Putative AMP-binding domain signature. 634 645 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 PRINTS PR00154 AMP-binding signature 641 649 8.9E-5 T 14-10-2018 IPR020459 AMP-binding A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 PRINTS PR00154 AMP-binding signature 629 640 8.9E-5 T 14-10-2018 IPR020459 AMP-binding A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Pfam PF00501 AMP-binding enzyme 493 891 2.1E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 SUPERFAMILY SSF56801 456 1014 2.62E-143 T 14-10-2018 A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 SUPERFAMILY SSF52777 30 224 4.89E-22 T 14-10-2018 A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 Pfam PF00550 Phosphopantetheine attachment site 1004 1070 2.5E-8 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_01610 bf3957293f4cf6814c376431cd27aca2 1080 SMART SM00823 Phosphopantetheine attachment site 1002 1076 0.002 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_24305 e4b856585fb11f61b21967a1d4c3227a 483 Gene3D G3DSA:2.115.10.20 1 294 1.9E-92 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_24305 e4b856585fb11f61b21967a1d4c3227a 483 SUPERFAMILY SSF49899 294 465 1.37E-7 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_24305 e4b856585fb11f61b21967a1d4c3227a 483 Gene3D G3DSA:2.60.120.200 295 482 1.4E-15 T 14-10-2018 A4R43_24305 e4b856585fb11f61b21967a1d4c3227a 483 SUPERFAMILY SSF75005 3 289 1.86E-88 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_24305 e4b856585fb11f61b21967a1d4c3227a 483 Pfam PF04616 Glycosyl hydrolases family 43 2 279 1.5E-87 T 14-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4R43_33595 4f2d29ed109097ad5b5655a2c5b29444 391 Pfam PF00005 ABC transporter 21 168 8.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_33595 4f2d29ed109097ad5b5655a2c5b29444 391 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_33595 4f2d29ed109097ad5b5655a2c5b29444 391 SUPERFAMILY SSF52540 7 231 4.88E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33595 4f2d29ed109097ad5b5655a2c5b29444 391 Gene3D G3DSA:3.40.50.300 5 278 1.3E-55 T 14-10-2018 A4R43_33595 4f2d29ed109097ad5b5655a2c5b29444 391 SMART SM00382 29 225 3.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_35500 66c6e7c1c38957301b8be0d2422416fe 332 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 332 131.943 T 14-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 A4R43_35500 66c6e7c1c38957301b8be0d2422416fe 332 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 324 1.6E-118 T 14-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 A4R43_35500 66c6e7c1c38957301b8be0d2422416fe 332 Gene3D G3DSA:3.40.50.10680 132 328 4.4E-57 T 14-10-2018 A4R43_35500 66c6e7c1c38957301b8be0d2422416fe 332 Pfam PF01933 Uncharacterised protein family UPF0052 3 294 4.9E-64 T 14-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 A4R43_35500 66c6e7c1c38957301b8be0d2422416fe 332 SUPERFAMILY SSF142338 3 326 9.55E-80 T 14-10-2018 A4R43_35500 66c6e7c1c38957301b8be0d2422416fe 332 Gene3D G3DSA:1.10.8.240 48 131 1.7E-34 T 14-10-2018 A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 7.1E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 SMART SM00345 12 71 8.6E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 148 296 7.5E-14 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 SUPERFAMILY SSF46785 5 75 2.1E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 Gene3D G3DSA:1.10.357.10 146 297 1.2E-32 T 14-10-2018 A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 Gene3D G3DSA:1.10.10.10 8 83 5.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 Gene3D G3DSA:1.10.10.60 85 145 3.2E-24 T 14-10-2018 A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 SUPERFAMILY SSF48498 155 296 2.78E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 Pfam PF00440 Bacterial regulatory proteins, tetR family 93 137 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25445 281c3f909ed7593c1267da3c304b278d 297 SUPERFAMILY SSF46689 87 144 1.8E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19205 7a1bf46e260a215ddb347c597bd5f867 330 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 161 235 4.3E-7 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A4R43_19205 7a1bf46e260a215ddb347c597bd5f867 330 Gene3D G3DSA:3.30.360.10 137 268 4.8E-90 T 14-10-2018 A4R43_19205 7a1bf46e260a215ddb347c597bd5f867 330 SUPERFAMILY SSF51735 2 147 5.78E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19205 7a1bf46e260a215ddb347c597bd5f867 330 Gene3D G3DSA:3.40.50.720 2 316 4.8E-90 T 14-10-2018 A4R43_19205 7a1bf46e260a215ddb347c597bd5f867 330 SUPERFAMILY SSF55347 122 253 7.68E-28 T 14-10-2018 A4R43_19205 7a1bf46e260a215ddb347c597bd5f867 330 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 1.5E-18 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_08620 cf1eda1cb0a338cf58f6943044454867 268 Pfam PF00753 Metallo-beta-lactamase superfamily 19 209 7.2E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_08620 cf1eda1cb0a338cf58f6943044454867 268 Gene3D G3DSA:3.60.15.10 1 232 1.4E-33 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_08620 cf1eda1cb0a338cf58f6943044454867 268 SUPERFAMILY SSF56281 3 229 1.4E-32 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_08620 cf1eda1cb0a338cf58f6943044454867 268 SMART SM00849 19 209 6.3E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_16680 00a2c2ee6bdd6a1404c039bc0d0b49cc 282 Pfam PF00581 Rhodanese-like domain 18 128 1.5E-15 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_16680 00a2c2ee6bdd6a1404c039bc0d0b49cc 282 Pfam PF00581 Rhodanese-like domain 158 269 1.3E-10 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_16680 00a2c2ee6bdd6a1404c039bc0d0b49cc 282 SUPERFAMILY SSF52821 2 148 1.96E-38 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_16680 00a2c2ee6bdd6a1404c039bc0d0b49cc 282 SMART SM00450 153 273 3.6E-15 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_16680 00a2c2ee6bdd6a1404c039bc0d0b49cc 282 SMART SM00450 6 132 1.6E-21 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_16680 00a2c2ee6bdd6a1404c039bc0d0b49cc 282 Gene3D G3DSA:3.40.250.10 1 149 1.2E-43 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_16680 00a2c2ee6bdd6a1404c039bc0d0b49cc 282 Gene3D G3DSA:3.40.250.10 155 275 1.4E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_16680 00a2c2ee6bdd6a1404c039bc0d0b49cc 282 SUPERFAMILY SSF52821 151 280 3.27E-31 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 10 519 1.4E-172 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 9 519 42.531 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 Gene3D G3DSA:3.40.140.20 214 365 2.9E-57 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 SUPERFAMILY SSF52335 9 198 3.14E-67 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 SMART SM00798 140 454 2.3E-181 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 Pfam PF02142 MGS-like domain 21 134 2.4E-26 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 SUPERFAMILY SSF53927 218 519 2.41E-114 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 SMART SM00851 21 135 1.3E-53 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 Gene3D G3DSA:3.40.50.1380 2 202 1.3E-87 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 PIRSF PIRSF000414 5 519 6.4E-197 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 Gene3D G3DSA:3.40.140.20 390 519 4.6E-52 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_34490 35c77c0eda326d9c1eb53792b264fce3 519 Pfam PF01808 AICARFT/IMPCHase bienzyme 140 453 1.3E-112 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 SUPERFAMILY SSF52540 307 507 7.59E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 Pfam PF00005 ABC transporter 338 471 1.3E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 Pfam PF00005 ABC transporter 21 188 2.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 Gene3D G3DSA:3.40.50.300 283 557 5.1E-64 T 14-10-2018 A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 5.0E-269 T 14-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 SMART SM00382 30 239 7.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 SMART SM00382 346 516 7.3E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 Pfam PF12848 ABC transporter 227 304 1.6E-13 T 14-10-2018 IPR032781 ABC-transporter extension domain A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 SUPERFAMILY SSF52540 8 240 7.95E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38805 5258c7afb45713912bfe8f305b9a9a8c 558 Gene3D G3DSA:3.40.50.300 2 282 2.0E-78 T 14-10-2018 A4R43_17365 252cf288245060486d0a0a5a189f7bc1 264 Gene3D G3DSA:3.40.50.10320 1 264 8.3E-67 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_17365 252cf288245060486d0a0a5a189f7bc1 264 SUPERFAMILY SSF102588 3 231 9.29E-53 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_17365 252cf288245060486d0a0a5a189f7bc1 264 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 146 1.3E-24 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4R43_08695 fb3ccf6b110582ade53078be9c75ff43 135 Pfam PF03795 YCII-related domain 17 109 7.0E-11 T 14-10-2018 IPR005545 YCII-related A4R43_08695 fb3ccf6b110582ade53078be9c75ff43 135 SUPERFAMILY SSF54909 21 125 1.53E-22 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_08695 fb3ccf6b110582ade53078be9c75ff43 135 Gene3D G3DSA:3.30.70.1060 1 129 1.6E-25 T 14-10-2018 A4R43_08160 74804399fdf4599134d3e033d2e0b8f5 565 Gene3D G3DSA:3.40.50.12780 8 450 5.9E-139 T 14-10-2018 A4R43_08160 74804399fdf4599134d3e033d2e0b8f5 565 SUPERFAMILY SSF56801 9 559 2.09E-104 T 14-10-2018 A4R43_08160 74804399fdf4599134d3e033d2e0b8f5 565 Pfam PF00501 AMP-binding enzyme 31 456 1.2E-82 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08160 74804399fdf4599134d3e033d2e0b8f5 565 Gene3D G3DSA:3.30.300.30 451 564 4.8E-35 T 14-10-2018 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 Pfam PF04055 Radical SAM superfamily 183 357 9.5E-22 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 181 201 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 14 473 9.1E-100 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 SUPERFAMILY SSF102114 171 404 1.05E-45 T 14-10-2018 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 Gene3D G3DSA:3.80.30.20 174 410 8.5E-65 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 Gene3D G3DSA:2.40.50.140 411 479 6.5E-8 T 14-10-2018 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 Gene3D G3DSA:3.40.50.12160 13 138 1.8E-33 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 14 474 1.3E-120 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 13 477 58.657 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 Pfam PF00919 Uncharacterized protein family UPF0004 14 108 2.1E-28 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A4R43_41295 b277b44b0607f46d89c26c20d4fd7036 482 SMART SM00729 177 399 2.0E-40 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 515 535 5.8E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 589 611 5.8E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 431 449 5.8E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 570 585 5.8E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 457 481 5.8E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 485 504 5.8E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 Gene3D G3DSA:2.130.10.120 64 394 6.1E-171 T 14-10-2018 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 SUPERFAMILY SSF53474 408 656 1.4E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 492 522 - T 14-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 Gene3D G3DSA:3.40.50.1820 18 626 6.1E-171 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 17 391 1.8E-37 T 14-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 Pfam PF00326 Prolyl oligopeptidase family 453 657 3.2E-50 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_12580 725b0dcc005fdb49a4e3c9560140b421 671 SUPERFAMILY SSF50993 17 386 9.94E-40 T 14-10-2018 A4R43_06425 41e2070a10496275899a08f69196b500 643 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 445 463 - T 14-10-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4R43_06425 41e2070a10496275899a08f69196b500 643 Pfam PF00942 Cellulose binding domain 500 573 2.2E-14 T 14-10-2018 IPR001956 Carbohydrate-binding module 3 GO:0005975|GO:0030248 A4R43_06425 41e2070a10496275899a08f69196b500 643 SUPERFAMILY SSF48208 35 488 1.09E-161 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_06425 41e2070a10496275899a08f69196b500 643 SUPERFAMILY SSF49384 494 641 3.61E-30 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A4R43_06425 41e2070a10496275899a08f69196b500 643 Gene3D G3DSA:2.60.40.710 490 640 5.9E-41 T 14-10-2018 IPR036966 Carbohydrate-binding module 3 superfamily GO:0005975|GO:0030248 A4R43_06425 41e2070a10496275899a08f69196b500 643 Pfam PF00759 Glycosyl hydrolase family 9 37 469 9.8E-139 T 14-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4R43_06425 41e2070a10496275899a08f69196b500 643 SMART SM01067 495 574 1.5E-18 T 14-10-2018 IPR001956 Carbohydrate-binding module 3 GO:0005975|GO:0030248 A4R43_06425 41e2070a10496275899a08f69196b500 643 Gene3D G3DSA:1.50.10.10 33 486 4.3E-199 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_29530 8d491b4894c896e1a948d69706c49f02 242 SMART SM00866 90 230 5.6E-13 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_29530 8d491b4894c896e1a948d69706c49f02 242 Pfam PF07702 UTRA domain 94 223 1.1E-19 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_29530 8d491b4894c896e1a948d69706c49f02 242 Gene3D G3DSA:1.10.10.10 3 78 1.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29530 8d491b4894c896e1a948d69706c49f02 242 Gene3D G3DSA:3.40.1410.10 88 233 2.3E-31 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_29530 8d491b4894c896e1a948d69706c49f02 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 3.6E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_29530 8d491b4894c896e1a948d69706c49f02 242 SUPERFAMILY SSF64288 61 234 9.42E-27 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_29530 8d491b4894c896e1a948d69706c49f02 242 SMART SM00345 14 73 2.5E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_29530 8d491b4894c896e1a948d69706c49f02 242 SUPERFAMILY SSF46785 4 77 3.1E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Pfam PF01541 GIY-YIG catalytic domain 19 92 1.2E-9 T 14-10-2018 IPR000305 GIY-YIG endonuclease A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 SUPERFAMILY SSF47781 576 686 2.95E-23 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Gene3D G3DSA:3.30.420.340 396 482 4.1E-24 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 SMART SM00278 665 684 0.33 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 SMART SM00278 633 652 97.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 478 3.5E-122 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Gene3D G3DSA:4.10.860.10 208 245 4.8E-6 T 14-10-2018 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Gene3D G3DSA:3.40.1440.10 6 103 1.9E-28 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 SMART SM00465 17 99 2.8E-20 T 14-10-2018 IPR000305 GIY-YIG endonuclease A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Pfam PF02151 UvrB/uvrC motif 210 242 1.4E-8 T 14-10-2018 IPR001943 UVR domain GO:0005515 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 684 30.035 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Pfam PF12826 Helix-hairpin-helix motif 637 689 2.0E-9 T 14-10-2018 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Gene3D G3DSA:3.30.420.340 537 626 4.2E-22 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Gene3D G3DSA:1.10.150.20 627 686 4.7E-19 T 14-10-2018 A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 SUPERFAMILY SSF46600 195 247 8.5E-14 T 14-10-2018 IPR036876 UVR domain superfamily A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 401 619 2.7E-48 T 14-10-2018 IPR001162 UvrC family homology region A4R43_04845 f9d1a6e72b2c27456bc7f0b783a190e0 699 SUPERFAMILY SSF82771 17 101 3.92E-22 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Gene3D G3DSA:3.40.50.12780 472 866 1.2E-88 T 14-10-2018 A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Gene3D G3DSA:3.30.300.30 867 974 3.5E-23 T 14-10-2018 A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Gene3D G3DSA:1.10.1200.10 975 1056 2.1E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Pfam PF13193 AMP-binding enzyme C-terminal domain 882 958 1.9E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Gene3D G3DSA:3.30.559.30 192 453 8.4E-93 T 14-10-2018 A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 SUPERFAMILY SSF52777 194 456 1.45E-39 T 14-10-2018 A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 SUPERFAMILY SSF56801 494 993 3.01E-110 T 14-10-2018 A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Pfam PF00550 Phosphopantetheine attachment site 985 1047 6.2E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 SUPERFAMILY SSF47336 977 1052 3.01E-11 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Pfam PF00501 AMP-binding enzyme 499 873 4.1E-66 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Pfam PF00668 Condensation domain 15 456 4.6E-50 T 14-10-2018 IPR001242 Condensation domain A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 ProSitePatterns PS00455 Putative AMP-binding domain signature. 615 626 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 Gene3D G3DSA:3.30.559.10 12 397 8.4E-93 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_37255 4bf56b5f46cee0b434a3d2185a2b368c 1062 SUPERFAMILY SSF52777 13 188 6.11E-37 T 14-10-2018 A4R43_29185 a9c32876640b10e24326f730a40feea7 212 Pfam PF08348 YheO-like PAS domain 7 114 5.8E-35 T 14-10-2018 IPR013559 YheO-like A4R43_29185 a9c32876640b10e24326f730a40feea7 212 Gene3D G3DSA:3.30.450.20 41 123 1.2E-5 T 14-10-2018 A4R43_29185 a9c32876640b10e24326f730a40feea7 212 Pfam PF13309 HTH domain 143 203 1.8E-17 T 14-10-2018 IPR039445 Transcriptional regulator DauR-like, HTH domain A4R43_29185 a9c32876640b10e24326f730a40feea7 212 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 12 120 1.0E-35 T 14-10-2018 IPR013559 YheO-like A4R43_41070 0a45c68fe848991eb7de17e8bc8b885a 151 SUPERFAMILY SSF89919 3 116 1.96E-26 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily A4R43_41070 0a45c68fe848991eb7de17e8bc8b885a 151 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 5 115 1.8E-20 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A4R43_41070 0a45c68fe848991eb7de17e8bc8b885a 151 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 3.0E-24 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A4R43_41070 0a45c68fe848991eb7de17e8bc8b885a 151 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 14-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 A4R43_41070 0a45c68fe848991eb7de17e8bc8b885a 151 Pfam PF02033 Ribosome-binding factor A 6 113 1.8E-25 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A4R43_41070 0a45c68fe848991eb7de17e8bc8b885a 151 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 5 113 24.272 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A4R43_41070 0a45c68fe848991eb7de17e8bc8b885a 151 Gene3D G3DSA:3.30.300.20 3 121 3.3E-24 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_04590 44e3137acd20d50327de0ad0232cb5c8 481 SUPERFAMILY SSF51905 19 217 5.18E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_04590 44e3137acd20d50327de0ad0232cb5c8 481 Gene3D G3DSA:3.90.700.10 295 408 8.2E-6 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_04590 44e3137acd20d50327de0ad0232cb5c8 481 SUPERFAMILY SSF51905 179 447 1.42E-5 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_04590 44e3137acd20d50327de0ad0232cb5c8 481 Pfam PF13454 FAD-NAD(P)-binding 4 145 1.4E-24 T 14-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain A4R43_04590 44e3137acd20d50327de0ad0232cb5c8 481 Gene3D G3DSA:3.50.50.60 53 279 2.4E-12 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_04590 44e3137acd20d50327de0ad0232cb5c8 481 Gene3D G3DSA:3.50.50.60 415 449 8.2E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34785 62559d7c3cdf1efcf18d9e79e24e74a2 368 SUPERFAMILY SSF51556 14 347 1.31E-68 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_34785 62559d7c3cdf1efcf18d9e79e24e74a2 368 Pfam PF00962 Adenosine/AMP deaminase 18 355 2.5E-87 T 14-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4R43_34785 62559d7c3cdf1efcf18d9e79e24e74a2 368 Gene3D G3DSA:3.20.20.140 3 364 3.0E-98 T 14-10-2018 A4R43_34785 62559d7c3cdf1efcf18d9e79e24e74a2 368 Hamap MF_00540 Adenosine deaminase [add]. 13 358 50.03 T 14-10-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 A4R43_34785 62559d7c3cdf1efcf18d9e79e24e74a2 368 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 19 355 7.5E-74 T 14-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A4R43_15815 e57bd5e498f512e41e3d433be0928d9b 287 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_15815 e57bd5e498f512e41e3d433be0928d9b 287 SUPERFAMILY SSF53613 2 287 9.35E-68 T 14-10-2018 IPR029056 Ribokinase-like A4R43_15815 e57bd5e498f512e41e3d433be0928d9b 287 Pfam PF00294 pfkB family carbohydrate kinase 2 286 1.5E-53 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_15815 e57bd5e498f512e41e3d433be0928d9b 287 Gene3D G3DSA:3.40.1190.20 1 287 3.7E-71 T 14-10-2018 IPR029056 Ribokinase-like A4R43_15815 e57bd5e498f512e41e3d433be0928d9b 287 PRINTS PR00990 Ribokinase signature 177 192 3.5E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_15815 e57bd5e498f512e41e3d433be0928d9b 287 PRINTS PR00990 Ribokinase signature 30 49 3.5E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_15815 e57bd5e498f512e41e3d433be0928d9b 287 PRINTS PR00990 Ribokinase signature 214 225 3.5E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_15815 e57bd5e498f512e41e3d433be0928d9b 287 PRINTS PR00990 Ribokinase signature 101 114 3.5E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_35475 c486a64dc18ea7cab774417c0f1cba53 134 Gene3D G3DSA:1.10.10.10 10 121 1.2E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35475 c486a64dc18ea7cab774417c0f1cba53 134 SMART SM00345 17 76 3.2E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_35475 c486a64dc18ea7cab774417c0f1cba53 134 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 1.1E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_35475 c486a64dc18ea7cab774417c0f1cba53 134 SUPERFAMILY SSF46785 6 80 4.1E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_16060 cbc6d2c254566ae9320785a1d9b81178 377 SUPERFAMILY SSF50022 15 128 1.44E-28 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_16060 cbc6d2c254566ae9320785a1d9b81178 377 SUPERFAMILY SSF55961 122 343 5.49E-32 T 14-10-2018 A4R43_16060 cbc6d2c254566ae9320785a1d9b81178 377 Gene3D G3DSA:3.30.530.90 151 377 2.0E-103 T 14-10-2018 A4R43_16060 cbc6d2c254566ae9320785a1d9b81178 377 Pfam PF00355 Rieske [2Fe-2S] domain 21 103 1.9E-17 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4R43_16060 cbc6d2c254566ae9320785a1d9b81178 377 Gene3D G3DSA:2.102.10.10 16 150 6.3E-44 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 357 78.631 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 SUPERFAMILY SSF56194 215 354 2.75E-30 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 SUPERFAMILY SSF56176 12 188 2.71E-40 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 Gene3D G3DSA:3.30.43.10 2 76 1.1E-21 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 217 353 6.4E-38 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 Gene3D G3DSA:3.90.78.10 234 356 6.1E-36 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 Gene3D G3DSA:3.30.465.10 79 228 6.6E-43 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 Pfam PF01565 FAD binding domain 26 157 2.2E-24 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_32735 2c81a562cb5c21d71fa0170eb84cdf82 357 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 12 353 2.2E-52 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_36230 db55d339061e913f2b1d6b262f6ece74 291 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 28 291 1.4E-89 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4R43_36230 db55d339061e913f2b1d6b262f6ece74 291 Gene3D G3DSA:3.20.20.60 27 290 6.6E-108 T 14-10-2018 A4R43_36230 db55d339061e913f2b1d6b262f6ece74 291 SUPERFAMILY SSF51621 29 289 1.96E-101 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_36230 db55d339061e913f2b1d6b262f6ece74 291 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 30 290 41.907 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4R43_36230 db55d339061e913f2b1d6b262f6ece74 291 Pfam PF02548 Ketopantoate hydroxymethyltransferase 29 285 1.9E-106 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4R43_36230 db55d339061e913f2b1d6b262f6ece74 291 PIRSF PIRSF000388 20 291 6.1E-109 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 SUPERFAMILY SSF50465 311 415 3.93E-30 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 PRINTS PR00315 GTP-binding elongation factor signature 101 112 2.7E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.7E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 PRINTS PR00315 GTP-binding elongation factor signature 85 95 2.7E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 PRINTS PR00315 GTP-binding elongation factor signature 138 147 2.7E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 PRINTS PR00315 GTP-binding elongation factor signature 65 73 2.7E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 Gene3D G3DSA:3.40.50.300 420 610 1.2E-70 T 14-10-2018 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 Pfam PF00009 Elongation factor Tu GTP binding domain 4 188 2.0E-40 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 437 611 34.953 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 Gene3D G3DSA:2.40.30.10 309 416 8.3E-35 T 14-10-2018 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 SUPERFAMILY SSF52540 3 210 1.45E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 Pfam PF01583 Adenylylsulphate kinase 438 590 8.8E-65 T 14-10-2018 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 414 3.2E-162 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 Gene3D G3DSA:3.40.50.300 1 214 1.5E-65 T 14-10-2018 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 SUPERFAMILY SSF50447 220 308 1.46E-15 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 Gene3D G3DSA:2.40.30.10 215 307 1.2E-18 T 14-10-2018 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 433 594 6.8E-63 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A4R43_37465 bd5c14f79ebe9a8c400a1a82bffcd642 611 SUPERFAMILY SSF52540 437 609 1.73E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 298 1.4E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.4E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.4E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 96 104 1.4E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 Gene3D G3DSA:3.50.50.100 4 365 1.6E-68 T 14-10-2018 A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.6E-10 T 14-10-2018 A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 1.6E-10 T 14-10-2018 A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.6E-10 T 14-10-2018 A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 SUPERFAMILY SSF51905 6 306 3.81E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_12880 f895f3e79fd2ece6ef569e1e5387fac2 394 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 272 3.9E-37 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.3E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 Gene3D G3DSA:1.10.10.60 4 54 1.3E-16 T 14-10-2018 A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 Pfam PF16859 Bacterial transcriptional repressor C-terminal 73 183 3.8E-25 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 SUPERFAMILY SSF46689 9 70 6.98E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.2E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.2E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 Gene3D G3DSA:1.10.357.10 55 192 3.9E-31 T 14-10-2018 A4R43_00800 088236e3a537e993f765000ccd9d7b39 196 SUPERFAMILY SSF48498 77 189 1.93E-18 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_04640 fddc1b88591ced3eeb78a46ff075e43b 161 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 154 7.6E-24 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_04640 fddc1b88591ced3eeb78a46ff075e43b 161 Gene3D G3DSA:1.10.10.10 89 161 9.4E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04640 fddc1b88591ced3eeb78a46ff075e43b 161 Gene3D G3DSA:1.10.1740.10 1 69 9.4E-16 T 14-10-2018 A4R43_04640 fddc1b88591ced3eeb78a46ff075e43b 161 SUPERFAMILY SSF88659 91 155 2.62E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_04640 fddc1b88591ced3eeb78a46ff075e43b 161 Pfam PF04545 Sigma-70, region 4 103 151 3.8E-15 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_04640 fddc1b88591ced3eeb78a46ff075e43b 161 SUPERFAMILY SSF88946 2 91 2.83E-18 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_04640 fddc1b88591ced3eeb78a46ff075e43b 161 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 27 59 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_04640 fddc1b88591ced3eeb78a46ff075e43b 161 Pfam PF04542 Sigma-70 region 2 6 73 6.4E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 SUPERFAMILY SSF56719 437 674 3.66E-74 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 SMART SM00387 34 195 6.3E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 Gene3D G3DSA:3.40.50.670 442 685 1.4E-84 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 SUPERFAMILY SSF54211 243 433 9.48E-31 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 Gene3D G3DSA:3.30.230.10 242 441 3.8E-45 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 Pfam PF01751 Toprim domain 462 562 1.4E-12 T 14-10-2018 IPR006171 TOPRIM domain A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 38 53 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 567 579 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 73 86 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 116 130 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 463 477 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 529 545 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 547 564 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 308 321 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR00418 DNA topoisomerase II family signature 615 631 3.6E-58 T 14-10-2018 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 SUPERFAMILY SSF55874 10 226 2.73E-52 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 139 8.6E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 SMART SM00433 38 676 3.5E-210 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 615 671 9.8E-24 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR01159 DNA gyrase subunit B signature 282 300 2.1E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR01159 DNA gyrase subunit B signature 652 668 2.1E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR01159 DNA gyrase subunit B signature 9 19 2.1E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR01159 DNA gyrase subunit B signature 201 216 2.1E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR01159 DNA gyrase subunit B signature 353 369 2.1E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR01159 DNA gyrase subunit B signature 417 437 2.1E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR01159 DNA gyrase subunit B signature 513 522 2.1E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 PRINTS PR01159 DNA gyrase subunit B signature 636 648 2.1E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 Gene3D G3DSA:3.30.565.10 6 241 4.5E-72 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 ProSitePatterns PS00177 DNA topoisomerase II signature. 465 473 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_37430 0d2d342a24b5524d14c4ab72ac9d66f4 685 Pfam PF00204 DNA gyrase B 243 433 6.2E-47 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_06905 842f8da42fbeabe6cc0eb8c24109a44b 411 SUPERFAMILY SSF103473 16 401 9.55E-31 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_06905 842f8da42fbeabe6cc0eb8c24109a44b 411 Pfam PF07690 Major Facilitator Superfamily 18 312 5.2E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_06905 842f8da42fbeabe6cc0eb8c24109a44b 411 Gene3D G3DSA:1.20.1250.20 13 399 1.8E-27 T 14-10-2018 A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 SUPERFAMILY SSF56281 22 437 2.54E-96 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 Gene3D G3DSA:3.60.15.10 23 449 2.2E-172 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 SMART SM00849 34 228 1.4E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 377 405 - T 14-10-2018 IPR001587 Ribonuclease J, conserved site A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 Pfam PF00753 Metallo-beta-lactamase superfamily 31 188 2.7E-14 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 Gene3D G3DSA:3.10.20.580 462 565 5.8E-15 T 14-10-2018 A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 Gene3D G3DSA:3.40.50.10710 220 378 2.2E-172 T 14-10-2018 A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 Hamap MF_01491 Ribonuclease J [rnj]. 17 565 40.562 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 374 410 1.3E-8 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 PIRSF PIRSF004803 16 565 9.7E-196 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A4R43_41245 cc0087fc304943548ea83ccb90dac329 565 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 23 562 4.3E-147 T 14-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 176 1.3E-14 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 Pfam PF08281 Sigma-70, region 4 124 175 8.0E-9 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 SUPERFAMILY SSF88659 119 177 7.48E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 SUPERFAMILY SSF54427 187 302 1.5E-15 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 Gene3D G3DSA:3.10.450.50 184 301 1.3E-8 T 14-10-2018 A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 SUPERFAMILY SSF88946 19 99 4.71E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 Pfam PF04542 Sigma-70 region 2 19 80 1.9E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 Gene3D G3DSA:1.10.1740.10 7 85 6.1E-9 T 14-10-2018 A4R43_12825 f09a0d827f19286d43f645e4cb012452 304 Gene3D G3DSA:1.10.10.10 108 180 7.6E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35160 7cda9177a7dc12a3a89310889a434f56 229 Gene3D G3DSA:1.25.40.10 8 158 5.0E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_35160 7cda9177a7dc12a3a89310889a434f56 229 Pfam PF07721 Tetratricopeptide repeat 12 30 0.79 T 14-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 A4R43_35160 7cda9177a7dc12a3a89310889a434f56 229 SUPERFAMILY SSF48452 12 129 3.8E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_35160 7cda9177a7dc12a3a89310889a434f56 229 SMART SM00028 37 70 460.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_35160 7cda9177a7dc12a3a89310889a434f56 229 SMART SM00028 71 104 0.0052 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_35160 7cda9177a7dc12a3a89310889a434f56 229 Pfam PF14559 Tetratricopeptide repeat 85 141 3.8E-7 T 14-10-2018 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 Gene3D G3DSA:3.30.420.40 5 371 2.6E-153 T 14-10-2018 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 Gene3D G3DSA:3.90.640.10 222 309 2.6E-153 T 14-10-2018 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 Gene3D G3DSA:1.20.1270.10 501 599 2.0E-19 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 Pfam PF00012 Hsp70 protein 4 591 1.6E-245 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 SUPERFAMILY SSF100920 378 534 2.62E-57 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 330 344 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 595 1.2E-288 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 SUPERFAMILY SSF53067 4 182 1.42E-61 T 14-10-2018 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 382 401 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 327 343 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 136 156 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 463 479 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 359 379 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 PRINTS PR00301 70kDa heat shock protein signature 195 205 1.4E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 Gene3D G3DSA:2.60.34.10 372 500 9.6E-56 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 SUPERFAMILY SSF53067 183 375 5.68E-67 T 14-10-2018 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 189 202 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 627 36.301 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 A4R43_29435 fe3f8939f9d81ce191faa9f303608e56 627 Gene3D G3DSA:3.30.420.40 178 360 2.6E-153 T 14-10-2018 A4R43_12985 2f06b905fa5c84acc0c07073d519cc6d 718 Pfam PF13245 AAA domain 171 548 2.2E-10 T 14-10-2018 A4R43_12985 2f06b905fa5c84acc0c07073d519cc6d 718 Gene3D G3DSA:3.40.50.300 429 564 1.0E-6 T 14-10-2018 A4R43_12985 2f06b905fa5c84acc0c07073d519cc6d 718 Gene3D G3DSA:3.40.50.300 159 341 6.2E-10 T 14-10-2018 A4R43_12985 2f06b905fa5c84acc0c07073d519cc6d 718 Gene3D G3DSA:3.40.50.300 650 717 5.1E-9 T 14-10-2018 A4R43_12985 2f06b905fa5c84acc0c07073d519cc6d 718 SUPERFAMILY SSF52540 160 701 2.45E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 Gene3D G3DSA:1.50.10.10 145 1053 0.0 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 SUPERFAMILY SSF49785 276 410 6.52E-6 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 PIRSF PIRSF010631 279 309 0.46 T 14-10-2018 IPR016007 Alpha-L-rhamnosidase A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 PIRSF PIRSF010631 14 222 2.0E-36 T 14-10-2018 IPR016007 Alpha-L-rhamnosidase A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 PIRSF PIRSF010631 306 1058 1.3E-251 T 14-10-2018 IPR016007 Alpha-L-rhamnosidase A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 SUPERFAMILY SSF49265 63 138 1.62E-6 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 SUPERFAMILY SSF48208 618 1029 7.37E-44 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 956 1026 1.6E-17 T 14-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 516 606 5.6E-28 T 14-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 Gene3D G3DSA:2.60.40.10 39 139 1.6E-31 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 620 954 4.2E-100 T 14-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 335 506 6.3E-58 T 14-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal A4R43_22605 da54e5ad028a39ccdfa70ec5c542183b 1058 Gene3D G3DSA:2.60.120.260 158 317 0.0 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_26690 d5751b1e6b8ecf8fe32578bcf1c98064 291 SMART SM00478 37 189 1.2E-41 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4R43_26690 d5751b1e6b8ecf8fe32578bcf1c98064 291 Gene3D G3DSA:1.10.1670.10 7 209 8.2E-70 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4R43_26690 d5751b1e6b8ecf8fe32578bcf1c98064 291 Gene3D G3DSA:1.10.340.30 18 130 8.2E-70 T 14-10-2018 A4R43_26690 d5751b1e6b8ecf8fe32578bcf1c98064 291 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 33 148 1.3E-15 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4R43_26690 d5751b1e6b8ecf8fe32578bcf1c98064 291 SUPERFAMILY SSF48150 5 216 3.77E-63 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4R43_26690 d5751b1e6b8ecf8fe32578bcf1c98064 291 Pfam PF00633 Helix-hairpin-helix motif 98 125 1.4E-6 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A4R43_23535 fd09b1087247403702bc2b04b27a7664 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 123 4.5E-11 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_23535 fd09b1087247403702bc2b04b27a7664 145 SUPERFAMILY SSF55961 3 140 6.05E-19 T 14-10-2018 A4R43_23535 fd09b1087247403702bc2b04b27a7664 145 Gene3D G3DSA:3.30.530.20 1 141 1.5E-23 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 SUPERFAMILY SSF47090 83 149 3.66E-20 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 SUPERFAMILY SSF47090 2 71 3.92E-15 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 SMART SM00646 238 353 1.9E-27 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 180 353 9.1E-37 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 Gene3D G3DSA:1.10.101.10 1 74 1.4E-16 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 Gene3D G3DSA:3.40.630.40 176 357 4.1E-40 T 14-10-2018 A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 SUPERFAMILY SSF53187 177 356 2.35E-42 T 14-10-2018 A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 Gene3D G3DSA:1.10.101.10 83 155 3.4E-20 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 Pfam PF01471 Putative peptidoglycan binding domain 92 147 7.8E-18 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_30480 ca2ccec1f5a73c4769d43192d61ba6eb 382 Pfam PF01471 Putative peptidoglycan binding domain 10 70 1.2E-12 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_31630 04e65e3a628434223dc596ed5985af9f 136 Pfam PF11349 Protein of unknown function (DUF3151) 7 131 2.4E-60 T 14-10-2018 IPR014487 Protein of unknown function DUF3151 A4R43_31630 04e65e3a628434223dc596ed5985af9f 136 PIRSF PIRSF017349 1 135 3.3E-61 T 14-10-2018 IPR014487 Protein of unknown function DUF3151 A4R43_31045 5308bb2a365e65d11d192135d434652b 400 SUPERFAMILY SSF88659 99 157 1.18E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_31045 5308bb2a365e65d11d192135d434652b 400 Pfam PF13176 Tetratricopeptide repeat 357 382 8.8E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_31045 5308bb2a365e65d11d192135d434652b 400 Pfam PF04542 Sigma-70 region 2 23 79 2.9E-6 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31045 5308bb2a365e65d11d192135d434652b 400 SUPERFAMILY SSF88946 8 93 1.37E-9 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31045 5308bb2a365e65d11d192135d434652b 400 Gene3D G3DSA:1.10.1740.10 2 98 1.9E-5 T 14-10-2018 A4R43_30815 56b7e68f19b05c44b19c551d9867a843 280 SUPERFAMILY SSF51338 3 252 2.07E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_30815 56b7e68f19b05c44b19c551d9867a843 280 Gene3D G3DSA:3.30.110.90 206 228 1.4E-27 T 14-10-2018 A4R43_30815 56b7e68f19b05c44b19c551d9867a843 280 Gene3D G3DSA:2.30.40.10 4 85 5.3E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_30815 56b7e68f19b05c44b19c551d9867a843 280 Pfam PF01979 Amidohydrolase family 159 255 1.1E-12 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_30815 56b7e68f19b05c44b19c551d9867a843 280 Gene3D G3DSA:2.30.40.10 229 262 1.4E-27 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_30815 56b7e68f19b05c44b19c551d9867a843 280 Gene3D G3DSA:1.20.58.520 158 205 1.4E-27 T 14-10-2018 A4R43_30815 56b7e68f19b05c44b19c551d9867a843 280 SUPERFAMILY SSF51556 129 229 5.78E-18 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 Gene3D G3DSA:3.40.50.2020 155 299 2.7E-110 T 14-10-2018 A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 SMART SM01400 12 128 1.6E-71 T 14-10-2018 A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 323 2.0E-115 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 2.9E-45 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 Gene3D G3DSA:3.40.50.2020 15 310 2.7E-110 T 14-10-2018 A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 7.4E-20 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 SUPERFAMILY SSF53271 77 314 8.56E-59 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_24020 3152c000dcc91fcb51338dd1d8d0ffff 326 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 12 323 45.091 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A4R43_30595 1ebbad308bc7f89078c94c66005d3736 204 SUPERFAMILY SSF82607 11 100 6.93E-8 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_30595 1ebbad308bc7f89078c94c66005d3736 204 Pfam PF02575 YbaB/EbfC DNA-binding family 10 99 1.2E-11 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_30595 1ebbad308bc7f89078c94c66005d3736 204 Gene3D G3DSA:3.30.1310.10 2 106 1.0E-9 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_38980 05079ad6543879a1b65664f4da702adb 315 SUPERFAMILY SSF88946 3 92 2.04E-27 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_38980 05079ad6543879a1b65664f4da702adb 315 Gene3D G3DSA:3.10.450.50 192 266 1.9E-8 T 14-10-2018 A4R43_38980 05079ad6543879a1b65664f4da702adb 315 SUPERFAMILY SSF88659 128 183 7.85E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_38980 05079ad6543879a1b65664f4da702adb 315 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 11 310 7.8E-90 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_38980 05079ad6543879a1b65664f4da702adb 315 Gene3D G3DSA:1.10.1740.10 2 105 2.4E-28 T 14-10-2018 A4R43_38980 05079ad6543879a1b65664f4da702adb 315 SUPERFAMILY SSF54427 195 299 3.0E-12 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_38980 05079ad6543879a1b65664f4da702adb 315 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 40 71 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_38980 05079ad6543879a1b65664f4da702adb 315 Pfam PF08281 Sigma-70, region 4 132 183 7.3E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_38980 05079ad6543879a1b65664f4da702adb 315 Gene3D G3DSA:1.10.10.10 126 191 4.1E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38980 05079ad6543879a1b65664f4da702adb 315 Pfam PF04542 Sigma-70 region 2 19 86 2.0E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_38980 05079ad6543879a1b65664f4da702adb 315 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 184 6.9E-22 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 172 5.8E-4 T 14-10-2018 A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 208 1.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 1.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 Pfam PF00106 short chain dehydrogenase 7 181 1.4E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 2.0E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 2.0E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 2.0E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 Gene3D G3DSA:3.40.50.720 4 227 4.5E-46 T 14-10-2018 A4R43_07530 aefeca48ce756fd27c359713e908ae42 228 SUPERFAMILY SSF51735 6 210 4.26E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37650 acb695be70a9bf09177d813c76c675fc 343 Gene3D G3DSA:3.40.47.10 6 192 2.5E-59 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37650 acb695be70a9bf09177d813c76c675fc 343 SUPERFAMILY SSF53901 5 193 2.88E-42 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37650 acb695be70a9bf09177d813c76c675fc 343 Gene3D G3DSA:3.40.47.10 196 343 3.1E-34 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37650 acb695be70a9bf09177d813c76c675fc 343 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 256 326 1.1E-5 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_37650 acb695be70a9bf09177d813c76c675fc 343 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 120 192 2.8E-15 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_37650 acb695be70a9bf09177d813c76c675fc 343 SUPERFAMILY SSF53901 174 327 7.69E-16 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_40795 fec5df576b3d8dcb50120ffaf7766efb 333 Gene3D G3DSA:3.30.360.10 137 255 1.3E-10 T 14-10-2018 A4R43_40795 fec5df576b3d8dcb50120ffaf7766efb 333 Gene3D G3DSA:3.40.50.720 6 136 1.3E-10 T 14-10-2018 A4R43_40795 fec5df576b3d8dcb50120ffaf7766efb 333 SUPERFAMILY SSF51735 2 165 6.19E-11 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40815 ef19b6a946f9ae4392ecc291d5e67278 293 Gene3D G3DSA:3.40.50.720 4 270 3.9E-43 T 14-10-2018 A4R43_40815 ef19b6a946f9ae4392ecc291d5e67278 293 Gene3D G3DSA:3.30.360.10 122 285 3.9E-43 T 14-10-2018 A4R43_40815 ef19b6a946f9ae4392ecc291d5e67278 293 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 106 7.3E-19 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_40815 ef19b6a946f9ae4392ecc291d5e67278 293 SUPERFAMILY SSF51735 3 127 8.01E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40815 ef19b6a946f9ae4392ecc291d5e67278 293 SUPERFAMILY SSF55347 152 233 6.38E-8 T 14-10-2018 A4R43_40215 561f05bccecf95ea85bd242d7e48f434 473 Gene3D G3DSA:1.20.1250.20 266 473 3.1E-19 T 14-10-2018 A4R43_40215 561f05bccecf95ea85bd242d7e48f434 473 Pfam PF07690 Major Facilitator Superfamily 27 419 1.6E-40 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_40215 561f05bccecf95ea85bd242d7e48f434 473 Gene3D G3DSA:1.20.1250.20 18 225 7.5E-36 T 14-10-2018 A4R43_40215 561f05bccecf95ea85bd242d7e48f434 473 SUPERFAMILY SSF103473 19 472 7.06E-61 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_05560 42e783b347210c95be4dd6369f547bc0 157 SUPERFAMILY SSF55961 12 154 9.55E-27 T 14-10-2018 A4R43_05560 42e783b347210c95be4dd6369f547bc0 157 Gene3D G3DSA:3.30.530.20 2 157 1.5E-27 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_05560 42e783b347210c95be4dd6369f547bc0 157 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 129 2.1E-11 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_28650 464db93476e94ecef2d4b5ec499d7254 437 Gene3D G3DSA:2.60.120.200 13 293 3.2E-83 T 14-10-2018 A4R43_28650 464db93476e94ecef2d4b5ec499d7254 437 Gene3D G3DSA:2.60.120.260 295 436 3.4E-41 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_28650 464db93476e94ecef2d4b5ec499d7254 437 SMART SM00606 301 437 2.2E-50 T 14-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 A4R43_28650 464db93476e94ecef2d4b5ec499d7254 437 Pfam PF00722 Glycosyl hydrolases family 16 67 272 9.7E-13 T 14-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 A4R43_28650 464db93476e94ecef2d4b5ec499d7254 437 SUPERFAMILY SSF49899 14 291 6.94E-47 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_28650 464db93476e94ecef2d4b5ec499d7254 437 Pfam PF03422 Carbohydrate binding module (family 6) 309 435 5.5E-39 T 14-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 A4R43_28650 464db93476e94ecef2d4b5ec499d7254 437 SUPERFAMILY SSF49785 300 436 9.86E-34 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SUPERFAMILY SSF52540 265 523 5.31E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 Gene3D G3DSA:1.10.10.10 3 99 2.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SUPERFAMILY SSF48452 707 907 3.03E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 Gene3D G3DSA:1.25.40.10 679 925 2.5E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SMART SM01043 103 248 1.2E-42 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 Gene3D G3DSA:3.40.50.300 262 419 1.6E-29 T 14-10-2018 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 PRINTS PR00364 Disease resistance protein signature 461 475 5.1E-9 T 14-10-2018 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 PRINTS PR00364 Disease resistance protein signature 296 311 5.1E-9 T 14-10-2018 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 PRINTS PR00364 Disease resistance protein signature 374 388 5.1E-9 T 14-10-2018 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SMART SM00028 837 870 390.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SMART SM00028 717 750 17.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SMART SM00028 877 910 31.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SMART SM00028 757 790 25.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SMART SM00028 797 830 460.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SMART SM00028 108 141 80.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 Gene3D G3DSA:1.25.40.10 101 261 5.6E-45 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SMART SM00862 23 96 4.9E-4 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 Pfam PF00931 NB-ARC domain 288 501 1.3E-8 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SUPERFAMILY SSF46894 10 96 2.52E-10 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 SUPERFAMILY SSF48452 98 263 7.15E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26045 d1a2588fe1ccd512cbf366f3f6da11ce 933 Pfam PF03704 Bacterial transcriptional activator domain 103 248 1.9E-41 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 215 401 7.5E-52 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 Gene3D G3DSA:3.40.50.720 7 279 3.9E-84 T 14-10-2018 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 PRINTS PR00084 Mannitol dehydrogenase signature 31 41 7.2E-13 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 PRINTS PR00084 Mannitol dehydrogenase signature 217 230 7.2E-13 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 PRINTS PR00084 Mannitol dehydrogenase signature 247 262 7.2E-13 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 30 182 9.3E-29 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 Gene3D G3DSA:1.10.1040.10 281 466 3.5E-44 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 217 229 - T 14-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 SUPERFAMILY SSF48179 282 463 1.02E-37 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_02390 4d8eef123d82ad6b8f280722924676cd 468 SUPERFAMILY SSF51735 16 280 4.99E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 Gene3D G3DSA:2.60.120.560 759 987 3.6E-73 T 14-10-2018 A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 Gene3D G3DSA:2.60.120.380 70 162 4.3E-12 T 14-10-2018 A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 SUPERFAMILY SSF56988 78 194 1.09E-10 T 14-10-2018 A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 SUPERFAMILY SSF63829 219 512 7.19E-15 T 14-10-2018 A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 Gene3D G3DSA:2.120.10.30 244 426 2.5E-5 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 Pfam PF07691 PA14 domain 30 164 7.8E-19 T 14-10-2018 IPR011658 PA14 domain A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 SUPERFAMILY SSF49785 656 792 5.24E-22 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 SMART SM00758 29 169 1.2E-27 T 14-10-2018 IPR011658 PA14 domain A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 Pfam PF06439 Domain of Unknown Function (DUF1080) 796 985 1.6E-35 T 14-10-2018 IPR010496 Domain of unknown function DUF1080 A4R43_00700 2fdde7c4c7b66e49face8e8a68418c94 987 Pfam PF16990 Carbohydrate binding module (family 35) 663 792 3.8E-8 T 14-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 A4R43_30195 9025bdf99d3964b8819f5cb51f7de73f 355 Gene3D G3DSA:3.20.20.30 19 347 1.3E-68 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_30195 9025bdf99d3964b8819f5cb51f7de73f 355 SUPERFAMILY SSF51679 27 347 1.27E-59 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_30195 9025bdf99d3964b8819f5cb51f7de73f 355 Pfam PF00296 Luciferase-like monooxygenase 29 319 1.1E-54 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_01500 1f41ac5c54b880e8b1b5b7568c598087 368 SUPERFAMILY SSF56601 34 352 7.17E-67 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_01500 1f41ac5c54b880e8b1b5b7568c598087 368 Gene3D G3DSA:3.40.710.10 30 367 2.2E-81 T 14-10-2018 A4R43_01500 1f41ac5c54b880e8b1b5b7568c598087 368 Pfam PF00144 Beta-lactamase 48 354 2.2E-49 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 24 199 34.57 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 Gene3D G3DSA:3.30.160.20 40 108 8.7E-29 T 14-10-2018 A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 Gene3D G3DSA:3.30.230.10 113 202 9.8E-35 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 SUPERFAMILY SSF54211 115 194 2.78E-24 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 Pfam PF00333 Ribosomal protein S5, N-terminal domain 49 111 1.3E-27 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 SUPERFAMILY SSF54768 47 112 3.77E-22 T 14-10-2018 A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 ProSitePatterns PS00585 Ribosomal protein S5 signature. 64 96 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 Pfam PF03719 Ribosomal protein S5, C-terminal domain 123 193 6.9E-28 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A4R43_33925 edaf4cd5c78c777cd42fba0c8a285949 214 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 48 199 2.5E-67 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4R43_33235 183d2eab2105226614d877f3ac92fcda 354 Gene3D G3DSA:3.40.50.970 91 250 7.9E-25 T 14-10-2018 A4R43_33235 183d2eab2105226614d877f3ac92fcda 354 SUPERFAMILY SSF52518 25 352 1.86E-78 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_33235 183d2eab2105226614d877f3ac92fcda 354 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 70 217 4.5E-29 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 Pfam PF07724 AAA domain (Cdc48 subfamily) 63 250 3.2E-33 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 SUPERFAMILY SSF52540 32 322 9.19E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 SMART SM00382 64 211 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 SMART SM01086 257 347 8.8E-14 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 258 328 2.7E-16 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 68 86 4.1E-26 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 113 131 4.1E-26 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 146 164 4.1E-26 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 180 194 4.1E-26 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 Gene3D G3DSA:1.10.8.60 257 348 8.7E-16 T 14-10-2018 A4R43_09950 070df6fde3c3209eca0035f57f0fc500 349 Gene3D G3DSA:3.40.50.300 25 255 3.2E-55 T 14-10-2018 A4R43_27845 f54f771b4d1992548ccda03c271540ec 653 Gene3D G3DSA:3.40.50.12780 73 522 3.5E-66 T 14-10-2018 A4R43_27845 f54f771b4d1992548ccda03c271540ec 653 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 38 93 1.4E-13 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 A4R43_27845 f54f771b4d1992548ccda03c271540ec 653 Pfam PF13193 AMP-binding enzyme C-terminal domain 544 614 2.8E-5 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_27845 f54f771b4d1992548ccda03c271540ec 653 Gene3D G3DSA:3.30.300.30 525 635 2.3E-12 T 14-10-2018 A4R43_27845 f54f771b4d1992548ccda03c271540ec 653 ProSitePatterns PS00455 Putative AMP-binding domain signature. 270 281 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_27845 f54f771b4d1992548ccda03c271540ec 653 Pfam PF00501 AMP-binding enzyme 105 527 7.5E-49 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_27845 f54f771b4d1992548ccda03c271540ec 653 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 6 647 2.8E-237 T 14-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 A4R43_27845 f54f771b4d1992548ccda03c271540ec 653 SUPERFAMILY SSF56801 37 627 9.42E-123 T 14-10-2018 A4R43_38665 c0d34e144c9ca210d072c05de4a79b44 396 Gene3D G3DSA:1.10.260.40 4 70 3.6E-13 T 14-10-2018 A4R43_38665 c0d34e144c9ca210d072c05de4a79b44 396 SUPERFAMILY SSF47413 3 68 6.76E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_38665 c0d34e144c9ca210d072c05de4a79b44 396 SMART SM00530 10 66 2.9E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_38665 c0d34e144c9ca210d072c05de4a79b44 396 Pfam PF13560 Helix-turn-helix domain 6 66 1.6E-13 T 14-10-2018 A4R43_08595 e66eee463566cbbca07fb61ba2a062ef 222 Pfam PF01674 Lipase (class 2) 30 185 1.8E-13 T 14-10-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 A4R43_08595 e66eee463566cbbca07fb61ba2a062ef 222 SUPERFAMILY SSF53474 26 147 4.39E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08595 e66eee463566cbbca07fb61ba2a062ef 222 Gene3D G3DSA:3.40.50.1820 11 222 1.5E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 Gene3D G3DSA:1.20.1080.10 1 225 6.1E-59 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 ProSitePatterns PS00221 MIP family signature. 41 49 - T 14-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 SUPERFAMILY SSF81338 4 222 8.37E-51 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 PRINTS PR00783 Major intrinsic protein family signature 60 79 2.8E-30 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 PRINTS PR00783 Major intrinsic protein family signature 154 176 2.8E-30 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 PRINTS PR00783 Major intrinsic protein family signature 202 222 2.8E-30 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 PRINTS PR00783 Major intrinsic protein family signature 115 133 2.8E-30 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 PRINTS PR00783 Major intrinsic protein family signature 23 47 2.8E-30 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4R43_35015 8e408bd98242947d8c64d1a3ef822204 226 Pfam PF00230 Major intrinsic protein 14 219 3.3E-34 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4R43_11495 11f5d93ec1a26ea8edcb568daf258641 390 Gene3D G3DSA:1.10.10.10 2 75 9.3E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11495 11f5d93ec1a26ea8edcb568daf258641 390 SUPERFAMILY SSF46785 9 73 5.91E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_11495 11f5d93ec1a26ea8edcb568daf258641 390 Pfam PF00480 ROK family 83 333 4.2E-26 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_11495 11f5d93ec1a26ea8edcb568daf258641 390 Gene3D G3DSA:3.30.420.40 78 210 2.0E-24 T 14-10-2018 A4R43_11495 11f5d93ec1a26ea8edcb568daf258641 390 SUPERFAMILY SSF53067 82 373 1.3E-30 T 14-10-2018 A4R43_11495 11f5d93ec1a26ea8edcb568daf258641 390 Gene3D G3DSA:3.30.420.40 211 354 1.9E-21 T 14-10-2018 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Pfam PF00486 Transcriptional regulatory protein, C terminal 11 81 1.6E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Pfam PF13424 Tetratricopeptide repeat 790 856 6.6E-8 T 14-10-2018 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Pfam PF13424 Tetratricopeptide repeat 869 935 2.9E-7 T 14-10-2018 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Pfam PF13424 Tetratricopeptide repeat 704 775 1.3E-10 T 14-10-2018 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SUPERFAMILY SSF46894 8 81 2.83E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SMART SM00028 704 737 9.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SMART SM00028 784 817 280.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SMART SM00028 744 777 190.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SMART SM00028 904 937 24.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SMART SM00028 824 857 6.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SUPERFAMILY SSF48452 84 251 1.23E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Gene3D G3DSA:1.10.10.10 1 83 3.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SUPERFAMILY SSF52540 247 512 6.11E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Gene3D G3DSA:1.25.40.10 672 950 1.4E-46 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SMART SM01043 88 229 1.7E-36 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SMART SM00862 3 81 2.5E-12 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SUPERFAMILY SSF48452 696 889 1.46E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Pfam PF03704 Bacterial transcriptional activator domain 88 229 3.4E-34 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Gene3D G3DSA:3.40.50.300 249 404 7.4E-27 T 14-10-2018 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Gene3D G3DSA:1.25.40.10 85 246 1.2E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 PRINTS PR00364 Disease resistance protein signature 285 300 1.4E-9 T 14-10-2018 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 PRINTS PR00364 Disease resistance protein signature 362 376 1.4E-9 T 14-10-2018 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 PRINTS PR00364 Disease resistance protein signature 447 461 1.4E-9 T 14-10-2018 A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 SMART SM00382 282 418 2.3E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_37795 b0b0d23c076f2e415ee3985b6d249345 971 Pfam PF00931 NB-ARC domain 266 516 1.9E-16 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 PIRSF PIRSF004983 1 554 8.7E-139 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 Gene3D G3DSA:3.40.50.970 2 203 8.9E-72 T 14-10-2018 A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 Gene3D G3DSA:3.40.50.970 361 550 8.1E-62 T 14-10-2018 A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 SUPERFAMILY SSF52518 364 542 1.21E-22 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 550 32.419 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 SUPERFAMILY SSF52518 8 185 1.77E-34 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 407 524 3.2E-6 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 Gene3D G3DSA:3.40.50.1220 215 358 5.4E-22 T 14-10-2018 A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 179 3.9E-31 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_33035 93a7f79388eb3a723f0b64ff516432e9 554 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 425 3.5E-113 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A4R43_04440 3c6e55d9557de145252dc8acea084870 251 Gene3D G3DSA:3.20.20.140 3 247 2.6E-38 T 14-10-2018 A4R43_04440 3c6e55d9557de145252dc8acea084870 251 SUPERFAMILY SSF51556 4 245 1.74E-32 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_04440 3c6e55d9557de145252dc8acea084870 251 Pfam PF04909 Amidohydrolase 38 238 9.5E-17 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 Pfam PF03466 LysR substrate binding domain 87 290 1.5E-29 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 SUPERFAMILY SSF46785 3 86 1.56E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 Gene3D G3DSA:1.10.10.10 1 84 9.1E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.8E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.8E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.8E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 Gene3D G3DSA:3.40.190.290 91 297 5.9E-30 T 14-10-2018 A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02835 1c7a5ad811600d6b1a498214e18c429f 300 SUPERFAMILY SSF53850 88 292 5.61E-27 T 14-10-2018 A4R43_10540 517e5f5d363306027545c11245972ef8 323 SMART SM00304 73 125 6.3E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_10540 517e5f5d363306027545c11245972ef8 323 Gene3D G3DSA:3.30.565.10 215 323 5.1E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_10540 517e5f5d363306027545c11245972ef8 323 SUPERFAMILY SSF55874 207 323 2.15E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_10540 517e5f5d363306027545c11245972ef8 323 Pfam PF07730 Histidine kinase 138 202 1.7E-17 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_20270 134287452345313fcfb70de275ab4aa1 137 SUPERFAMILY SSF54427 13 135 1.22E-30 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_20270 134287452345313fcfb70de275ab4aa1 137 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 14 132 1.5E-26 T 14-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 A4R43_20270 134287452345313fcfb70de275ab4aa1 137 Gene3D G3DSA:3.10.450.50 13 137 9.3E-34 T 14-10-2018 A4R43_20270 134287452345313fcfb70de275ab4aa1 137 Pfam PF14534 Domain of unknown function (DUF4440) 18 125 7.6E-12 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 A4R43_21785 0b7d273010a7c323053124c279a539b2 270 SUPERFAMILY SSF52833 77 264 1.24E-24 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_21785 0b7d273010a7c323053124c279a539b2 270 Pfam PF13462 Thioredoxin 87 264 2.6E-18 T 14-10-2018 IPR012336 Thioredoxin-like fold A4R43_21785 0b7d273010a7c323053124c279a539b2 270 Gene3D G3DSA:3.40.30.10 56 270 1.2E-41 T 14-10-2018 A4R43_24720 32001811ed7f0907839a119488981456 349 Pfam PF03741 Integral membrane protein TerC family 68 270 5.0E-57 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A4R43_24720 32001811ed7f0907839a119488981456 349 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 301 4.7E-127 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 SUPERFAMILY SSF50249 65 127 1.59E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 4.6E-24 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 Gene3D G3DSA:2.40.50.140 128 186 2.0E-24 T 14-10-2018 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 SUPERFAMILY SSF50104 2 63 4.45E-20 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 1.5E-21 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 49.093 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 5.2E-26 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 Gene3D G3DSA:2.30.30.30 1 62 4.3E-27 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 SUPERFAMILY SSF50249 129 185 4.97E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 SMART SM01185 67 121 2.2E-27 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 14-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 Gene3D G3DSA:2.40.50.140 64 127 1.2E-24 T 14-10-2018 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 7.1E-77 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 SMART SM00841 129 184 3.3E-31 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A4R43_04695 322780e348b61daa1ba8a380c2240dd4 187 PIRSF PIRSF005901 1 186 8.6E-68 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP A4R43_14510 e3b5f7557775d2830b015c1829ad4a89 242 Gene3D G3DSA:3.30.70.2330 9 105 1.3E-5 T 14-10-2018 A4R43_08320 dd1945c9c91887f8a21e0bb1eff7878e 345 SUPERFAMILY SSF51679 1 335 3.66E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_08320 dd1945c9c91887f8a21e0bb1eff7878e 345 Gene3D G3DSA:3.20.20.30 1 336 1.1E-94 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_08320 dd1945c9c91887f8a21e0bb1eff7878e 345 Pfam PF00296 Luciferase-like monooxygenase 3 312 5.4E-50 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_08320 dd1945c9c91887f8a21e0bb1eff7878e 345 TIGRFAM TIGR04020 seco_metab_LLM: natural product biosynthesis luciferase-like monooxygenase domain 3 337 4.0E-139 T 14-10-2018 IPR024011 Natural product biosynthesis luciferase-like monooxygenase domain A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 Gene3D G3DSA:1.20.150.20 383 513 1.9E-47 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 SUPERFAMILY SSF47917 383 511 4.19E-44 T 14-10-2018 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 47.895 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 Gene3D G3DSA:3.40.50.300 97 382 9.0E-115 T 14-10-2018 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 SUPERFAMILY SSF52540 99 381 1.25E-92 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 SUPERFAMILY SSF50615 14 97 4.45E-23 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 Gene3D G3DSA:2.40.30.20 4 96 1.9E-27 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 1.3E-237 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 3.0E-65 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 1.2E-12 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22360 76abe1f3bcb03a76630834b3037f498b 546 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 506 3.6E-46 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_37690 83eff0d63bd3fcc38e915a83799f4738 348 Gene3D G3DSA:2.40.30.170 208 285 7.8E-10 T 14-10-2018 A4R43_37690 83eff0d63bd3fcc38e915a83799f4738 348 Pfam PF01471 Putative peptidoglycan binding domain 118 168 3.7E-6 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_37690 83eff0d63bd3fcc38e915a83799f4738 348 Gene3D G3DSA:2.40.50.100 182 207 7.8E-10 T 14-10-2018 A4R43_37690 83eff0d63bd3fcc38e915a83799f4738 348 Gene3D G3DSA:1.10.101.10 108 170 6.0E-6 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_37690 83eff0d63bd3fcc38e915a83799f4738 348 Gene3D G3DSA:2.20.25.620 286 344 7.8E-10 T 14-10-2018 A4R43_37690 83eff0d63bd3fcc38e915a83799f4738 348 SUPERFAMILY SSF47090 105 169 8.89E-7 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_37690 83eff0d63bd3fcc38e915a83799f4738 348 Pfam PF13437 HlyD family secretion protein 181 267 3.0E-8 T 14-10-2018 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 Gene3D G3DSA:1.10.490.10 1 132 3.6E-36 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 Gene3D G3DSA:2.40.30.10 133 230 6.8E-21 T 14-10-2018 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 268 277 6.0E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 243 262 6.0E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 165 175 6.0E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 SUPERFAMILY SSF63380 138 232 1.43E-22 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 Gene3D G3DSA:3.40.50.80 233 366 3.6E-27 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 Pfam PF00042 Globin 3 95 1.9E-11 T 14-10-2018 IPR000971 Globin GO:0020037 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 268 277 2.1E-12 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 243 262 2.1E-12 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 165 177 2.1E-12 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 SUPERFAMILY SSF52343 236 365 1.05E-29 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 Pfam PF00175 Oxidoreductase NAD-binding domain 244 345 5.5E-17 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 SUPERFAMILY SSF46458 3 128 4.66E-34 T 14-10-2018 IPR009050 Globin-like superfamily A4R43_31420 52b1ec1d2c990fdfefbfd0fa7c9f75a0 367 Pfam PF00970 Oxidoreductase FAD-binding domain 141 232 1.8E-12 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4R43_35760 998aeb93cdf36990986156fa40cca8b5 131 SUPERFAMILY SSF54427 39 104 3.84E-5 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_19025 6eaf904e23e55159cbc3905a4b853b65 220 SMART SM00855 3 164 1.1E-8 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_19025 6eaf904e23e55159cbc3905a4b853b65 220 Gene3D G3DSA:3.40.50.1240 2 216 1.1E-28 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_19025 6eaf904e23e55159cbc3905a4b853b65 220 SUPERFAMILY SSF53254 1 210 1.12E-31 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_19025 6eaf904e23e55159cbc3905a4b853b65 220 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 205 8.6E-20 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 SUPERFAMILY SSF46785 2 67 5.03E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 Pfam PF07729 FCD domain 81 201 9.5E-28 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 Gene3D G3DSA:1.10.10.10 1 71 3.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 23 37 1.7E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 53 1.7E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 SMART SM00895 81 202 3.0E-21 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 63 3.8E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 Gene3D G3DSA:1.20.120.530 78 212 2.2E-32 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 SMART SM00345 4 63 1.4E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05365 420931b2a72bb8b5e2c9c9e44d2e0d94 213 SUPERFAMILY SSF48008 79 209 1.62E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.50.720 7342 7489 2.7E-28 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF53901 4729 5104 7.98E-101 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3498 3615 2.1E-42 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4991 5106 1.1E-41 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1987 2103 7.4E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 281 396 1.2E-39 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6456 6570 4.0E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 7855 7970 4.1E-42 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.47.10 3235 3686 1.1E-186 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.47.10 4725 5173 9.0E-186 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.47.10 7597 8041 6.9E-178 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.47.10 1723 2169 5.4E-185 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.47.10 6194 6643 5.5E-183 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 7760 7776 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4896 4912 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.50.720 7052 7341 5.9E-52 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.50.720 4113 4612 2.2E-147 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 186 202 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF55048 8263 8316 3.01E-9 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.30.70.3290 3687 4097 5.3E-151 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF53901 1727 2093 4.05E-102 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1666 1681 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF52151 8122 8408 3.14E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF52151 3747 4037 8.37E-68 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 5840 6072 4.57E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1367 1541 6.7E-54 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5841 6008 8.0E-54 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2869 3048 4.2E-58 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4360 4539 7.7E-42 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8734 8910 4.6E-58 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:1.10.1200.10 4623 4714 1.3E-33 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:1.10.1200.10 7490 7583 5.7E-32 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:1.10.1200.10 8990 9080 3.5E-31 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:1.10.1200.10 1622 1715 1.2E-35 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:1.10.1200.10 3134 3226 4.7E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:1.10.1200.10 6094 6185 3.5E-32 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF53901 7602 7967 1.37E-102 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 2866 3109 4.92E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00550 Phosphopantetheine attachment site 7512 7578 3.3E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00550 Phosphopantetheine attachment site 1642 1707 3.5E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00550 Phosphopantetheine attachment site 9008 9074 2.5E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00550 Phosphopantetheine attachment site 4644 4710 1.1E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00550 Phosphopantetheine attachment site 3154 3219 3.0E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00550 Phosphopantetheine attachment site 6114 6179 3.2E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF08990 Erythronolide synthase docking 3 27 4.5E-10 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF47336 6105 6218 1.01E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 8730 8961 1.89E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3178 3193 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 7097 7280 1.42E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 7295 7438 2.39E-11 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF55048 692 749 1.31E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6138 6153 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.366.10 3749 4052 5.3E-151 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.366.10 5255 5538 2.8E-156 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.366.10 2255 2549 5.8E-164 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.366.10 550 860 7.6E-154 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.366.10 8124 8421 8.0E-147 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.366.10 6712 6990 7.8E-143 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.30.70.3290 6644 7034 7.8E-143 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF53901 30 392 6.7E-95 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 273 7.8E-82 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7606 7847 8.1E-83 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6203 6447 1.1E-86 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3243 3490 4.5E-91 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1731 1979 1.1E-90 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4733 4983 7.3E-93 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF47336 9000 9084 5.63E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00825 Beta-ketoacyl synthase 1733 2156 1.2E-216 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00825 Beta-ketoacyl synthase 6205 6623 2.0E-213 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00825 Beta-ketoacyl synthase 4735 5159 7.5E-212 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00825 Beta-ketoacyl synthase 7608 8023 5.4E-203 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00825 Beta-ketoacyl synthase 36 449 6.0E-201 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00825 Beta-ketoacyl synthase 3245 3668 9.1E-216 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4669 4684 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF47336 7505 7621 4.97E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 2657 2855 2.76E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6360 6376 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF52151 5253 5526 1.44E-69 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00823 Phosphopantetheine attachment site 6111 6183 1.1E-32 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00823 Phosphopantetheine attachment site 4642 4714 4.1E-29 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00823 Phosphopantetheine attachment site 1639 1711 4.4E-33 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00823 Phosphopantetheine attachment site 3151 3223 3.7E-30 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00823 Phosphopantetheine attachment site 9006 9078 1.0E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00823 Phosphopantetheine attachment site 7510 7582 1.6E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF53901 6200 6568 1.3E-101 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF47336 3146 3258 1.7E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 1366 1606 2.17E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM01294 6112 6179 4.7E-8 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM01294 9007 9074 5.2E-6 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM01294 3152 3219 1.7E-6 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM01294 1640 1707 1.1E-6 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM01294 7511 7578 1.1E-6 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM01294 4643 4710 2.2E-5 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF55048 2380 2437 3.66E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.30.70.3290 8042 8465 8.0E-147 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3403 3419 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.50.720 1205 1605 1.0E-121 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.30.70.3290 2170 2593 5.8E-164 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 8527 8724 4.66E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF52151 2253 2540 6.28E-75 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.50.720 5598 6082 1.0E-156 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.50.720 8482 8980 1.1E-158 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.50.720 2609 3120 2.7E-156 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7537 7552 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00698 Acyl transferase domain 6713 7005 3.1E-52 T 14-10-2018 IPR014043 Acyl transferase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00698 Acyl transferase domain 551 875 9.1E-56 T 14-10-2018 IPR014043 Acyl transferase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00698 Acyl transferase domain 2257 2564 2.9E-55 T 14-10-2018 IPR014043 Acyl transferase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00698 Acyl transferase domain 8126 8437 5.7E-48 T 14-10-2018 IPR014043 Acyl transferase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00698 Acyl transferase domain 3749 4068 4.0E-89 T 14-10-2018 IPR014043 Acyl transferase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF00698 Acyl transferase domain 5256 5554 2.9E-56 T 14-10-2018 IPR014043 Acyl transferase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 1206 1356 5.9E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF08659 KR domain 4360 4538 4.4E-54 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF08659 KR domain 1367 1539 4.3E-55 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF08659 KR domain 8734 8908 1.6E-58 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF08659 KR domain 5841 6007 1.0E-52 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF08659 KR domain 2869 3047 1.3E-58 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF08659 KR domain 7333 7416 1.6E-13 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1892 1908 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF53901 3240 3613 1.41E-101 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 552 857 3.2E-117 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2257 2546 2.3E-123 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3751 4049 4.7E-126 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8126 8418 5.9E-108 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6714 6987 3.8E-107 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5257 5535 7.6E-118 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF55048 3875 3940 2.22E-10 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF52151 6711 6975 2.12E-70 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SMART SM00826 926 1091 2.6E-82 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6573 6688 3.5E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 7973 8088 3.6E-16 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5109 5221 4.3E-16 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2106 2221 5.5E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3618 3729 2.2E-10 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 399 516 2.7E-14 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.40.47.10 16 450 3.7E-177 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Pfam PF14765 Polyketide synthase dehydratase 926 1200 2.2E-51 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.30.70.3290 5174 5582 2.8E-156 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.30.70.3290 469 904 7.6E-154 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF52151 548 847 3.92E-72 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF55048 5379 5433 7.46E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 Gene3D G3DSA:3.10.129.110 915 1204 2.7E-111 T 14-10-2018 A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF47336 4637 4748 6.54E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 5644 5828 6.5E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF55048 6837 6891 1.7E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 ProSitePatterns PS00012 Phosphopantetheine attachment site. 9033 9048 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 4356 4603 1.1E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF51735 4158 4347 7.48E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38450 97d862b819036878fa37d0d1024a06ec 9164 SUPERFAMILY SSF47336 1633 1746 1.31E-25 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_11530 dc83af7e241615806301ec91d8b22758 692 Gene3D G3DSA:3.30.70.270 324 489 6.3E-59 T 14-10-2018 A4R43_11530 dc83af7e241615806301ec91d8b22758 692 Pfam PF13487 HD domain 565 627 1.1E-17 T 14-10-2018 A4R43_11530 dc83af7e241615806301ec91d8b22758 692 SUPERFAMILY SSF109604 513 673 1.16E-30 T 14-10-2018 A4R43_11530 dc83af7e241615806301ec91d8b22758 692 SUPERFAMILY SSF55073 329 485 1.18E-48 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_11530 dc83af7e241615806301ec91d8b22758 692 Pfam PF00990 Diguanylate cyclase, GGDEF domain 324 483 1.8E-47 T 14-10-2018 IPR000160 GGDEF domain A4R43_11530 dc83af7e241615806301ec91d8b22758 692 SMART SM00471 513 645 4.4E-7 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_11530 dc83af7e241615806301ec91d8b22758 692 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 322 485 9.8E-49 T 14-10-2018 IPR000160 GGDEF domain A4R43_11530 dc83af7e241615806301ec91d8b22758 692 SMART SM00267 313 487 5.4E-62 T 14-10-2018 IPR000160 GGDEF domain A4R43_11530 dc83af7e241615806301ec91d8b22758 692 Gene3D G3DSA:1.10.3210.10 494 677 1.7E-55 T 14-10-2018 A4R43_39705 8912e798141abe1e064383dc2f354ddd 253 Hamap MF_00201 DNA repair protein RecO [recO]. 3 244 27.309 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4R43_39705 8912e798141abe1e064383dc2f354ddd 253 SUPERFAMILY SSF50249 2 80 2.57E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_39705 8912e798141abe1e064383dc2f354ddd 253 Pfam PF02565 Recombination protein O C terminal 87 239 9.3E-35 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4R43_39705 8912e798141abe1e064383dc2f354ddd 253 Pfam PF11967 Recombination protein O N terminal 4 80 1.1E-25 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal A4R43_39705 8912e798141abe1e064383dc2f354ddd 253 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 234 7.5E-37 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4R43_39705 8912e798141abe1e064383dc2f354ddd 253 Gene3D G3DSA:2.40.50.140 1 82 2.0E-28 T 14-10-2018 A4R43_39705 8912e798141abe1e064383dc2f354ddd 253 SUPERFAMILY SSF57863 83 233 1.05E-41 T 14-10-2018 IPR037278 ARFGAP/RecO-like zinc finger A4R43_26640 156a56effeef41cb2e09c548bd6f71bb 456 Gene3D G3DSA:3.30.420.40 233 445 9.2E-17 T 14-10-2018 A4R43_26640 156a56effeef41cb2e09c548bd6f71bb 456 SUPERFAMILY SSF53067 237 435 1.04E-10 T 14-10-2018 A4R43_26640 156a56effeef41cb2e09c548bd6f71bb 456 Gene3D G3DSA:3.30.420.40 8 232 3.1E-42 T 14-10-2018 A4R43_26640 156a56effeef41cb2e09c548bd6f71bb 456 PIRSF PIRSF000538 319 427 3.6E-9 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_26640 156a56effeef41cb2e09c548bd6f71bb 456 PIRSF PIRSF000538 4 270 1.3E-36 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_26640 156a56effeef41cb2e09c548bd6f71bb 456 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 10 234 5.9E-23 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4R43_26640 156a56effeef41cb2e09c548bd6f71bb 456 SUPERFAMILY SSF53067 11 233 3.11E-34 T 14-10-2018 A4R43_26640 156a56effeef41cb2e09c548bd6f71bb 456 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 304 403 3.4E-10 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 Gene3D G3DSA:3.90.800.10 76 195 1.4E-92 T 14-10-2018 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 39 52 5.4E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 5.4E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 24 35 5.4E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 5.4E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 10 22 5.4E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 SUPERFAMILY SSF52374 7 319 6.97E-98 T 14-10-2018 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 SUPERFAMILY SSF48163 320 490 1.01E-37 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 7 323 4.7E-79 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 Gene3D G3DSA:1.10.10.350 394 493 1.8E-28 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 Gene3D G3DSA:1.10.1160.10 252 335 4.1E-27 T 14-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 7 488 3.3E-129 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 6 490 31.192 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4R43_19930 203474998c5263b4a0ad5f260b2248d6 495 Gene3D G3DSA:3.40.50.620 7 248 1.4E-92 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_29985 83d131f9e035bf10acd3b04c6ce08e59 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 3.1E-24 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_29985 83d131f9e035bf10acd3b04c6ce08e59 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 374 3.2E-30 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_29985 83d131f9e035bf10acd3b04c6ce08e59 384 SUPERFAMILY SSF56645 2 241 3.93E-66 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_29985 83d131f9e035bf10acd3b04c6ce08e59 384 Gene3D G3DSA:1.20.140.10 233 378 2.6E-37 T 14-10-2018 A4R43_29985 83d131f9e035bf10acd3b04c6ce08e59 384 SUPERFAMILY SSF47203 227 382 1.18E-41 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_29985 83d131f9e035bf10acd3b04c6ce08e59 384 Gene3D G3DSA:1.10.540.10 1 118 4.4E-28 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_29985 83d131f9e035bf10acd3b04c6ce08e59 384 Gene3D G3DSA:2.40.110.10 120 232 5.8E-32 T 14-10-2018 A4R43_29985 83d131f9e035bf10acd3b04c6ce08e59 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 6.9E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_18900 ecc1b43ef221ab9d7ec9d52121294644 533 Pfam PF00474 Sodium:solute symporter family 43 452 5.9E-95 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_18900 ecc1b43ef221ab9d7ec9d52121294644 533 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 43 451 3.2E-59 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_18900 ecc1b43ef221ab9d7ec9d52121294644 533 Gene3D G3DSA:1.20.1730.10 30 520 2.8E-59 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_08195 cbe73f842816fa0750995ceff6ba3c7b 169 SUPERFAMILY SSF55729 1 165 5.23E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_08195 cbe73f842816fa0750995ceff6ba3c7b 169 Pfam PF13420 Acetyltransferase (GNAT) domain 1 154 6.1E-24 T 14-10-2018 A4R43_08195 cbe73f842816fa0750995ceff6ba3c7b 169 Gene3D G3DSA:3.40.630.30 1 166 2.3E-51 T 14-10-2018 A4R43_31305 cf5bea5fc3bf2b27cfcdd05180444970 253 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_31305 cf5bea5fc3bf2b27cfcdd05180444970 253 Gene3D G3DSA:3.90.226.10 1 197 2.4E-78 T 14-10-2018 A4R43_31305 cf5bea5fc3bf2b27cfcdd05180444970 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 203 2.5E-42 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_31305 cf5bea5fc3bf2b27cfcdd05180444970 253 SUPERFAMILY SSF52096 2 243 1.84E-67 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 3.0E-67 T 14-10-2018 A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 Gene3D G3DSA:3.40.50.720 1 249 8.0E-83 T 14-10-2018 A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 176 9.0E-4 T 14-10-2018 A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 SUPERFAMILY SSF51735 7 248 9.65E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02505 c60dc92beab4dc814b3257df04c67ed4 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 245 2.5E-79 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2775 3025 9.2E-92 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4446 4697 1.7E-93 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 955 1204 1.4E-93 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF53901 951 1317 9.26E-106 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.30.70.3290 1573 1988 8.2E-153 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2712 2727 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF55048 1775 1834 1.18E-8 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00825 Beta-ketoacyl synthase 10 412 1.3E-188 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00825 Beta-ketoacyl synthase 2777 3201 1.7E-230 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00825 Beta-ketoacyl synthase 957 1380 8.1E-223 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00825 Beta-ketoacyl synthase 4448 4872 4.4E-229 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM01294 866 933 2.9E-6 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM01294 5951 6018 5.4E-4 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM01294 4356 4423 5.1E-5 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM01294 2686 2753 8.3E-6 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4083 4260 1.4E-49 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2415 2588 4.8E-57 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5693 5862 3.5E-54 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.30.70.3290 3214 3634 1.1E-146 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF51735 4083 4276 1.61E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF55048 3422 3484 4.71E-10 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF51735 2241 2404 9.84E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF51735 2414 2639 1.28E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.30.70.3290 425 834 1.9E-156 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF52151 3297 3587 1.15E-65 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.50.720 5568 5932 5.6E-98 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.50.720 2275 2653 5.9E-117 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.50.720 3936 4331 2.7E-107 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1117 1133 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF52151 1652 1933 1.15E-69 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 500 788 4.9E-116 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3301 3591 1.3E-109 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1656 1941 4.7E-119 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4964 5251 5.4E-121 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00698 Acyl transferase domain 499 808 4.6E-56 T 14-10-2018 IPR014043 Acyl transferase A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00698 Acyl transferase domain 3299 3609 5.2E-88 T 14-10-2018 IPR014043 Acyl transferase A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00698 Acyl transferase domain 4963 5239 8.0E-56 T 14-10-2018 IPR014043 Acyl transferase A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00698 Acyl transferase domain 1654 1959 3.1E-86 T 14-10-2018 IPR014043 Acyl transferase A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4382 4397 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF53901 6 407 3.43E-83 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF55048 5085 5146 2.49E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3152 3262 1.4E-13 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4823 4935 9.4E-19 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 367 472 1.9E-13 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1330 1387 6.2E-10 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.366.10 3299 3593 1.1E-146 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.366.10 1654 1944 8.2E-153 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.366.10 498 792 1.9E-156 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.366.10 4962 5253 1.8E-154 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2938 2954 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.10.129.110 5303 5567 5.2E-90 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.10.129.110 3642 3935 2.5E-101 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.10.129.110 1996 2274 1.6E-103 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 364 1.4E-34 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3033 3149 4.7E-45 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1212 1327 1.7E-42 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4705 4820 1.2E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF52151 496 780 6.8E-73 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:1.10.1200.10 2665 2758 7.7E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:1.10.1200.10 4335 4428 3.2E-33 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00823 Phosphopantetheine attachment site 2685 2757 2.0E-33 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00823 Phosphopantetheine attachment site 865 937 4.1E-27 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00823 Phosphopantetheine attachment site 4355 4427 7.8E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00823 Phosphopantetheine attachment site 5950 6022 3.3E-30 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.47.10 952 1420 1.7E-201 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF52151 4961 5252 1.99E-75 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF51735 5511 5683 1.65E-7 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.47.10 2771 3205 2.6E-189 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.47.10 4442 4877 6.0E-191 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.40.47.10 5 417 1.8E-168 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF53901 2772 3146 1.01E-102 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF53901 4442 4817 1.35E-106 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF51735 3912 4075 1.34E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00550 Phosphopantetheine attachment site 867 933 4.1E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00550 Phosphopantetheine attachment site 5952 6018 6.7E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00550 Phosphopantetheine attachment site 2687 2753 6.7E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF00550 Phosphopantetheine attachment site 4357 4423 5.2E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF47336 861 969 4.06E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF47336 5943 6025 2.22E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF47336 2679 2790 3.27E-25 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF55048 622 683 7.19E-10 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF14765 Polyketide synthase dehydratase 3653 3931 2.0E-58 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF14765 Polyketide synthase dehydratase 2007 2268 3.4E-56 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF14765 Polyketide synthase dehydratase 5314 5564 5.2E-47 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:3.30.70.3290 4886 5295 1.8E-154 T 14-10-2018 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF47336 4349 4461 3.8E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4610 4626 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SUPERFAMILY SSF51735 5691 5923 7.16E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00826 5314 5463 1.2E-65 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00826 3653 3822 4.0E-70 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 SMART SM00826 2007 2159 2.6E-77 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF08659 KR domain 5693 5861 2.1E-53 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF08659 KR domain 4085 4259 7.1E-54 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Pfam PF08659 KR domain 2415 2586 5.9E-57 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 ProSitePatterns PS00012 Phosphopantetheine attachment site. 892 907 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:1.10.1200.10 848 940 1.9E-31 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37740 95118f9a32b848ca7b87f65133da1401 6094 Gene3D G3DSA:1.10.1200.10 5934 6025 1.3E-32 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Gene3D G3DSA:3.10.129.110 883 1144 1.8E-71 T 14-10-2018 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Pfam PF00550 Phosphopantetheine attachment site 1184 1250 1.0E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SUPERFAMILY SSF55048 672 731 4.97E-9 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SMART SM00826 894 1047 3.8E-57 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SUPERFAMILY SSF101173 3 34 5.49E-5 T 14-10-2018 IPR036299 Polyketide synthase, docking domain superfmaily A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Gene3D G3DSA:1.10.1200.10 1166 1256 6.1E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SUPERFAMILY SSF53901 31 399 2.66E-103 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 287 402 2.2E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Gene3D G3DSA:3.40.366.10 550 832 4.5E-147 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 279 9.2E-87 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SMART SM00823 Phosphopantetheine attachment site 1182 1254 8.0E-34 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SMART SM01294 1183 1250 2.1E-4 T 14-10-2018 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Pfam PF00698 Acyl transferase domain 551 847 2.9E-83 T 14-10-2018 IPR014043 Acyl transferase A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SUPERFAMILY SSF52151 549 818 1.57E-63 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Gene3D G3DSA:3.30.70.3290 470 875 4.5E-147 T 14-10-2018 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 552 829 3.7E-108 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SUPERFAMILY SSF47336 1177 1259 3.27E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Gene3D G3DSA:3.40.47.10 16 456 1.2E-186 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Pfam PF14765 Polyketide synthase dehydratase 894 1088 5.6E-40 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1209 1224 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 SMART SM00825 Beta-ketoacyl synthase 36 455 2.7E-222 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 405 517 1.6E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 192 208 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07930 6c27dd27e8ffbff3610030f2b5caee34 1323 Pfam PF08990 Erythronolide synthase docking 2 22 3.5E-9 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_41600 b350a34c87f562b75410cdf6515a66b1 490 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 483 1.5E-142 T 14-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_41600 b350a34c87f562b75410cdf6515a66b1 490 Pfam PF06974 Protein of unknown function (DUF1298) 331 480 1.6E-38 T 14-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_41600 b350a34c87f562b75410cdf6515a66b1 490 SUPERFAMILY SSF52777 39 161 2.78E-11 T 14-10-2018 A4R43_41600 b350a34c87f562b75410cdf6515a66b1 490 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 290 4.8E-76 T 14-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_41600 b350a34c87f562b75410cdf6515a66b1 490 Gene3D G3DSA:3.30.559.10 51 191 1.8E-6 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_41600 b350a34c87f562b75410cdf6515a66b1 490 SUPERFAMILY SSF52777 280 479 2.67E-7 T 14-10-2018 A4R43_28995 c3cfc0f33203fd186cd7373039f35bb8 374 Gene3D G3DSA:3.40.50.300 225 343 1.2E-8 T 14-10-2018 A4R43_28995 c3cfc0f33203fd186cd7373039f35bb8 374 PIRSF PIRSF029347 120 351 1.1E-31 T 14-10-2018 IPR014555 RecF-like A4R43_28995 c3cfc0f33203fd186cd7373039f35bb8 374 PIRSF PIRSF029347 4 121 3.8E-14 T 14-10-2018 IPR014555 RecF-like A4R43_28995 c3cfc0f33203fd186cd7373039f35bb8 374 Gene3D G3DSA:3.40.50.300 3 216 2.4E-9 T 14-10-2018 A4R43_28995 c3cfc0f33203fd186cd7373039f35bb8 374 SUPERFAMILY SSF52540 6 354 9.31E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28995 c3cfc0f33203fd186cd7373039f35bb8 374 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 27 314 2.0E-27 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_34475 d0ee7987e2d555309e22f48dfb98724e 290 Pfam PF17270 Family of unknown function (DUF5336) 8 164 7.4E-30 T 14-10-2018 IPR035166 Protein of unknown function DUF5336 A4R43_04720 677b5d9fac5503d095585a2512e72c78 430 ProSitePatterns PS00483 Dihydroorotase signature 2. 303 314 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04720 677b5d9fac5503d095585a2512e72c78 430 Pfam PF01979 Amidohydrolase family 49 421 1.3E-20 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_04720 677b5d9fac5503d095585a2512e72c78 430 Gene3D G3DSA:2.30.40.10 11 421 1.5E-130 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_04720 677b5d9fac5503d095585a2512e72c78 430 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 426 1.1E-138 T 14-10-2018 A4R43_04720 677b5d9fac5503d095585a2512e72c78 430 Gene3D G3DSA:3.20.20.140 54 369 1.5E-130 T 14-10-2018 A4R43_04720 677b5d9fac5503d095585a2512e72c78 430 Hamap MF_00220_B Dihydroorotase [pyrC]. 5 426 42.039 T 14-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04720 677b5d9fac5503d095585a2512e72c78 430 SUPERFAMILY SSF51338 15 429 2.23E-23 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_04720 677b5d9fac5503d095585a2512e72c78 430 SUPERFAMILY SSF51556 53 368 6.01E-96 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_13680 71e25833326f4f50d2d097077bfded27 187 SUPERFAMILY SSF88659 120 184 1.35E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_13680 71e25833326f4f50d2d097077bfded27 187 SUPERFAMILY SSF88946 5 100 7.38E-31 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_13680 71e25833326f4f50d2d097077bfded27 187 Gene3D G3DSA:1.10.1740.10 3 114 1.0E-33 T 14-10-2018 A4R43_13680 71e25833326f4f50d2d097077bfded27 187 Pfam PF04542 Sigma-70 region 2 26 92 7.5E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_13680 71e25833326f4f50d2d097077bfded27 187 Pfam PF08281 Sigma-70, region 4 129 179 3.6E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_13680 71e25833326f4f50d2d097077bfded27 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 182 1.6E-33 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_13680 71e25833326f4f50d2d097077bfded27 187 Gene3D G3DSA:1.10.10.10 123 185 2.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29070 4eae37b5c81598ad518c8e51653a4188 1053 Gene3D G3DSA:3.60.20.10 380 475 5.5E-12 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_29070 4eae37b5c81598ad518c8e51653a4188 1053 Gene3D G3DSA:3.60.20.10 517 712 4.4E-22 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_29070 4eae37b5c81598ad518c8e51653a4188 1053 Pfam PF00754 F5/8 type C domain 932 1047 1.8E-22 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4R43_29070 4eae37b5c81598ad518c8e51653a4188 1053 Gene3D G3DSA:1.10.439.10 102 261 5.1E-31 T 14-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 A4R43_29070 4eae37b5c81598ad518c8e51653a4188 1053 Gene3D G3DSA:2.60.120.260 920 1051 9.2E-34 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_29070 4eae37b5c81598ad518c8e51653a4188 1053 Pfam PF01804 Penicillin amidase 104 906 1.3E-125 T 14-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 A4R43_29070 4eae37b5c81598ad518c8e51653a4188 1053 SUPERFAMILY SSF56235 103 835 3.86E-103 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_29070 4eae37b5c81598ad518c8e51653a4188 1053 SUPERFAMILY SSF49785 923 1049 5.53E-25 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_22365 8881111f113cfd1aca48eefc73ca9712 272 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 233 252 - T 14-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22365 8881111f113cfd1aca48eefc73ca9712 272 Pfam PF00213 ATP synthase delta (OSCP) subunit 108 271 4.0E-38 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22365 8881111f113cfd1aca48eefc73ca9712 272 PRINTS PR00125 ATP synthase delta subunit signature 231 246 9.1E-10 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22365 8881111f113cfd1aca48eefc73ca9712 272 PRINTS PR00125 ATP synthase delta subunit signature 246 264 9.1E-10 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22365 8881111f113cfd1aca48eefc73ca9712 272 PRINTS PR00125 ATP synthase delta subunit signature 101 120 9.1E-10 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22365 8881111f113cfd1aca48eefc73ca9712 272 Hamap MF_01416 ATP synthase subunit delta [atpD]. 97 272 13.52 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22365 8881111f113cfd1aca48eefc73ca9712 272 SUPERFAMILY SSF47928 108 185 5.62E-5 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22365 8881111f113cfd1aca48eefc73ca9712 272 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 107 271 1.4E-27 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_03620 bde7ed05ba996aa469d4416d9602b21e 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 285 1.6E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_03620 bde7ed05ba996aa469d4416d9602b21e 315 Gene3D G3DSA:1.10.3720.10 82 290 4.0E-22 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_03620 bde7ed05ba996aa469d4416d9602b21e 315 SUPERFAMILY SSF161098 88 275 2.22E-26 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_13880 510df2d0ff0279ff4a87f6016c61f19e 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 1.2E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13880 510df2d0ff0279ff4a87f6016c61f19e 226 Gene3D G3DSA:1.10.357.10 5 198 1.7E-30 T 14-10-2018 A4R43_13880 510df2d0ff0279ff4a87f6016c61f19e 226 SUPERFAMILY SSF46689 16 94 1.49E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13880 510df2d0ff0279ff4a87f6016c61f19e 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 4.7E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13880 510df2d0ff0279ff4a87f6016c61f19e 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 4.7E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20515 70ea73f615b6280d43c4f778cc8c5032 333 Gene3D G3DSA:3.40.50.2300 149 320 2.0E-67 T 14-10-2018 A4R43_20515 70ea73f615b6280d43c4f778cc8c5032 333 SUPERFAMILY SSF53822 46 322 1.26E-57 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_20515 70ea73f615b6280d43c4f778cc8c5032 333 Gene3D G3DSA:3.40.50.2300 56 312 2.0E-67 T 14-10-2018 A4R43_20515 70ea73f615b6280d43c4f778cc8c5032 333 Pfam PF13407 Periplasmic binding protein domain 50 303 1.1E-48 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_17780 ec8d2ade477ad1ab81b911eb09364a3f 350 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 11 348 33.783 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_17780 ec8d2ade477ad1ab81b911eb09364a3f 350 Gene3D G3DSA:3.40.50.10210 56 329 1.8E-108 T 14-10-2018 A4R43_17780 ec8d2ade477ad1ab81b911eb09364a3f 350 Gene3D G3DSA:1.10.1610.10 12 336 1.8E-108 T 14-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_17780 ec8d2ade477ad1ab81b911eb09364a3f 350 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 13 346 8.8E-112 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_17780 ec8d2ade477ad1ab81b911eb09364a3f 350 SUPERFAMILY SSF52733 8 347 4.97E-99 T 14-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_17780 ec8d2ade477ad1ab81b911eb09364a3f 350 Pfam PF02277 Phosphoribosyltransferase 11 346 1.4E-117 T 14-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_15285 10bafc7566a863cde7403de53c585a54 288 PRINTS PR00412 Epoxide hydrolase signature 36 54 2.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_15285 10bafc7566a863cde7403de53c585a54 288 PRINTS PR00412 Epoxide hydrolase signature 263 285 2.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_15285 10bafc7566a863cde7403de53c585a54 288 PRINTS PR00412 Epoxide hydrolase signature 99 112 2.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_15285 10bafc7566a863cde7403de53c585a54 288 Pfam PF00561 alpha/beta hydrolase fold 31 137 2.5E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_15285 10bafc7566a863cde7403de53c585a54 288 SUPERFAMILY SSF53474 2 288 4.05E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_15285 10bafc7566a863cde7403de53c585a54 288 Gene3D G3DSA:3.40.50.1820 1 288 9.4E-77 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38720 7dae6765361e1cafe2b62d8dfa569120 281 Gene3D G3DSA:3.40.50.720 3 281 1.5E-66 T 14-10-2018 A4R43_38720 7dae6765361e1cafe2b62d8dfa569120 281 Pfam PF13460 NAD(P)H-binding 7 179 6.1E-20 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_38720 7dae6765361e1cafe2b62d8dfa569120 281 SUPERFAMILY SSF51735 2 274 1.26E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04550 b73896db19f8a01a54272d88bb8021b9 432 SUPERFAMILY SSF81301 31 189 6.87E-49 T 14-10-2018 A4R43_04550 b73896db19f8a01a54272d88bb8021b9 432 Gene3D G3DSA:3.40.50.150 195 410 9.4E-53 T 14-10-2018 A4R43_04550 b73896db19f8a01a54272d88bb8021b9 432 Pfam PF08241 Methyltransferase domain 245 338 1.7E-25 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_04550 b73896db19f8a01a54272d88bb8021b9 432 Pfam PF04229 GrpB protein 29 187 2.9E-52 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase A4R43_04550 b73896db19f8a01a54272d88bb8021b9 432 Gene3D G3DSA:3.30.460.10 25 193 1.6E-51 T 14-10-2018 A4R43_04550 b73896db19f8a01a54272d88bb8021b9 432 SUPERFAMILY SSF53335 202 405 1.38E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_07875 230297785128b3ae153b791442be496b 577 Gene3D G3DSA:3.40.50.970 382 577 1.5E-36 T 14-10-2018 A4R43_07875 230297785128b3ae153b791442be496b 577 SUPERFAMILY SSF52518 6 196 7.85E-35 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_07875 230297785128b3ae153b791442be496b 577 SUPERFAMILY SSF52518 391 576 1.97E-31 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_07875 230297785128b3ae153b791442be496b 577 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 215 321 8.6E-12 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_07875 230297785128b3ae153b791442be496b 577 Gene3D G3DSA:3.40.50.970 5 197 9.8E-51 T 14-10-2018 A4R43_07875 230297785128b3ae153b791442be496b 577 Gene3D G3DSA:3.40.50.1220 215 372 1.2E-27 T 14-10-2018 A4R43_07875 230297785128b3ae153b791442be496b 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 569 8.9E-17 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_07875 230297785128b3ae153b791442be496b 577 SUPERFAMILY SSF52467 177 365 4.53E-21 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_07875 230297785128b3ae153b791442be496b 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 191 6.0E-40 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_09280 94762d09411ead7a7307409445ae0c88 399 Gene3D G3DSA:3.40.50.620 91 315 2.2E-23 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_09280 94762d09411ead7a7307409445ae0c88 399 SUPERFAMILY SSF52402 93 310 3.39E-13 T 14-10-2018 A4R43_09280 94762d09411ead7a7307409445ae0c88 399 Pfam PF06508 Queuosine biosynthesis protein QueC 234 300 5.0E-5 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4R43_41270 8f22820d6768aefaeeb5806523752056 776 Pfam PF09397 Ftsk gamma domain 698 754 5.3E-22 T 14-10-2018 IPR018541 FtsK gamma domain A4R43_41270 8f22820d6768aefaeeb5806523752056 776 Gene3D G3DSA:3.30.980.40 286 388 6.8E-30 T 14-10-2018 A4R43_41270 8f22820d6768aefaeeb5806523752056 776 Pfam PF01580 FtsK/SpoIIIE family 392 592 7.1E-62 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_41270 8f22820d6768aefaeeb5806523752056 776 Gene3D G3DSA:1.10.10.10 697 758 1.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41270 8f22820d6768aefaeeb5806523752056 776 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 53 178 1.4E-8 T 14-10-2018 IPR025199 DNA translocase FtsK, 4TM region A4R43_41270 8f22820d6768aefaeeb5806523752056 776 SMART SM00843 693 757 7.2E-30 T 14-10-2018 IPR018541 FtsK gamma domain A4R43_41270 8f22820d6768aefaeeb5806523752056 776 SUPERFAMILY SSF46785 694 759 6.8E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_41270 8f22820d6768aefaeeb5806523752056 776 SUPERFAMILY SSF52540 366 664 5.31E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41270 8f22820d6768aefaeeb5806523752056 776 Gene3D G3DSA:3.40.50.300 389 678 9.3E-106 T 14-10-2018 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 Gene3D G3DSA:3.40.50.11540 53 231 1.8E-79 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 341 352 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 SUPERFAMILY SSF142984 241 323 2.22E-23 T 14-10-2018 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 Gene3D G3DSA:1.20.1440.230 327 424 1.5E-32 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 SUPERFAMILY SSF140490 326 417 9.42E-35 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 48 217 2.5E-48 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 Pfam PF10531 SLBB domain 243 290 5.3E-10 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 9 412 2.5E-189 T 14-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 Gene3D G3DSA:3.10.20.600 232 325 7.0E-31 T 14-10-2018 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 332 412 2.2E-32 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 SUPERFAMILY SSF142019 7 239 2.35E-87 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33105 7275e61d044a796eae07012cf420f36a 426 SMART SM00928 328 373 7.0E-24 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_28800 5444eb32e75edf429b19b1b4562ac7bb 328 SUPERFAMILY SSF53850 115 326 5.2E-5 T 14-10-2018 A4R43_28800 5444eb32e75edf429b19b1b4562ac7bb 328 SUPERFAMILY SSF46785 15 111 4.42E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_28800 5444eb32e75edf429b19b1b4562ac7bb 328 Gene3D G3DSA:1.10.10.10 14 108 3.0E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28800 5444eb32e75edf429b19b1b4562ac7bb 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 80 3.5E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 SUPERFAMILY SSF47203 229 378 4.83E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 2.1E-42 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 Gene3D G3DSA:2.40.110.10 123 234 7.8E-42 T 14-10-2018 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 218 1.2E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 Gene3D G3DSA:1.20.140.10 235 380 2.0E-43 T 14-10-2018 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 Gene3D G3DSA:1.10.540.10 5 122 8.7E-33 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 1.1E-27 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 SUPERFAMILY SSF56645 3 239 1.11E-77 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_05215 8c5e8fe44caf70112243cd20d8f9ab5c 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_12760 6484f0c644ac1e8126c2871b2a03cf99 525 Gene3D G3DSA:2.60.120.260 30 162 7.0E-35 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_12760 6484f0c644ac1e8126c2871b2a03cf99 525 SUPERFAMILY SSF49785 31 154 6.44E-24 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_12760 6484f0c644ac1e8126c2871b2a03cf99 525 Gene3D G3DSA:2.160.20.10 163 514 4.6E-87 T 14-10-2018 IPR012334 Pectin lyase fold A4R43_12760 6484f0c644ac1e8126c2871b2a03cf99 525 Pfam PF13229 Right handed beta helix region 253 443 2.8E-9 T 14-10-2018 IPR039448 Right handed beta helix domain A4R43_12760 6484f0c644ac1e8126c2871b2a03cf99 525 SUPERFAMILY SSF51126 161 493 5.16E-48 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_12760 6484f0c644ac1e8126c2871b2a03cf99 525 Pfam PF03422 Carbohydrate binding module (family 6) 48 154 4.7E-10 T 14-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 A4R43_09970 9af5b632871bcc81b444d54931558c39 141 Pfam PF12802 MarR family 34 91 2.2E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_09970 9af5b632871bcc81b444d54931558c39 141 SMART SM00347 27 127 1.7E-19 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_09970 9af5b632871bcc81b444d54931558c39 141 SUPERFAMILY SSF46785 8 127 1.39E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09970 9af5b632871bcc81b444d54931558c39 141 Gene3D G3DSA:1.10.10.10 2 137 3.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 Gene3D G3DSA:3.30.390.30 351 462 4.0E-23 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.0E-21 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 2.0E-21 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 2.0E-21 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 2.0E-21 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 454 2.4E-18 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 SUPERFAMILY SSF55424 348 459 8.42E-24 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PIRSF PIRSF000350 1 458 2.7E-55 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 Gene3D G3DSA:3.50.50.60 6 324 4.8E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 SUPERFAMILY SSF51905 1 329 3.96E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 313 1.0E-44 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 Gene3D G3DSA:3.50.50.60 150 268 4.8E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 9.1E-53 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 9.1E-53 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 9.1E-53 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 9.1E-53 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 9.1E-53 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 9.1E-53 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 9.1E-53 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 9.1E-53 T 14-10-2018 A4R43_18105 13bab1d5b8725ff9290bd68df10c3e1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 9.1E-53 T 14-10-2018 A4R43_29260 e9315f08f52851c9ebbb92ecd9f43510 278 SUPERFAMILY SSF53335 19 258 1.51E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_29260 e9315f08f52851c9ebbb92ecd9f43510 278 PIRSF PIRSF017393 1 267 1.2E-63 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_29260 e9315f08f52851c9ebbb92ecd9f43510 278 Gene3D G3DSA:3.40.50.150 2 269 3.4E-76 T 14-10-2018 A4R43_29260 e9315f08f52851c9ebbb92ecd9f43510 278 Pfam PF04672 S-adenosyl methyltransferase 11 253 2.0E-59 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 43 359 9.7E-51 T 14-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 SUPERFAMILY SSF54197 39 199 4.16E-52 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 Gene3D G3DSA:3.30.428.10 42 358 3.3E-95 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 174 191 - T 14-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 SUPERFAMILY SSF54197 203 360 1.68E-37 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 Gene3D G3DSA:3.30.428.10 71 198 3.3E-95 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 39 198 1.2E-39 T 14-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 PIRSF PIRSF000808 36 361 3.2E-110 T 14-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4R43_25040 b08d83cbbd7e9ab0fb1bffed535a8c72 361 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 209 358 1.3E-19 T 14-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4R43_02495 ff4228d466a54ccb911fe83277c30604 370 Pfam PF00534 Glycosyl transferases group 1 178 316 1.8E-17 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_02495 ff4228d466a54ccb911fe83277c30604 370 SUPERFAMILY SSF53756 9 358 1.12E-43 T 14-10-2018 A4R43_02495 ff4228d466a54ccb911fe83277c30604 370 Gene3D G3DSA:3.40.50.2000 179 342 2.2E-24 T 14-10-2018 A4R43_02495 ff4228d466a54ccb911fe83277c30604 370 Gene3D G3DSA:3.40.50.2000 1 178 2.8E-8 T 14-10-2018 A4R43_06995 2e1a51f873044f8a6a6c2387f2037183 380 SUPERFAMILY SSF55031 186 296 1.57E-19 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_06995 2e1a51f873044f8a6a6c2387f2037183 380 PIRSF PIRSF037238 4 380 3.2E-110 T 14-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase A4R43_06995 2e1a51f873044f8a6a6c2387f2037183 380 SUPERFAMILY SSF53187 5 379 1.69E-44 T 14-10-2018 A4R43_06995 2e1a51f873044f8a6a6c2387f2037183 380 Pfam PF07687 Peptidase dimerisation domain 183 274 5.9E-17 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_06995 2e1a51f873044f8a6a6c2387f2037183 380 Pfam PF01546 Peptidase family M20/M25/M40 84 375 3.9E-28 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_06995 2e1a51f873044f8a6a6c2387f2037183 380 Gene3D G3DSA:3.40.630.10 21 368 1.4E-102 T 14-10-2018 A4R43_06995 2e1a51f873044f8a6a6c2387f2037183 380 Gene3D G3DSA:3.30.70.360 186 293 1.4E-102 T 14-10-2018 A4R43_16795 8dfb560168c9adcab87044f4948bfc6c 191 SMART SM00507 20 69 4.0E-4 T 14-10-2018 IPR003615 HNH nuclease A4R43_16795 8dfb560168c9adcab87044f4948bfc6c 191 Pfam PF01844 HNH endonuclease 32 70 1.9E-8 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A4R43_16795 8dfb560168c9adcab87044f4948bfc6c 191 Gene3D G3DSA:3.30.40.60 12 87 2.5E-7 T 14-10-2018 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 308 316 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 280 326 1.2E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 SUPERFAMILY SSF54292 257 342 8.65E-19 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 Gene3D G3DSA:3.40.50.80 151 263 3.1E-21 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 Gene3D G3DSA:3.10.20.30 267 343 2.8E-14 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 SUPERFAMILY SSF52343 143 266 1.57E-26 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 Pfam PF00175 Oxidoreductase NAD-binding domain 157 247 7.9E-6 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 PRINTS PR00409 Phthalate dioxygenase reductase family signature 233 241 6.0E-28 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 PRINTS PR00409 Phthalate dioxygenase reductase family signature 75 85 6.0E-28 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 PRINTS PR00409 Phthalate dioxygenase reductase family signature 97 111 6.0E-28 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 PRINTS PR00409 Phthalate dioxygenase reductase family signature 181 190 6.0E-28 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 PRINTS PR00409 Phthalate dioxygenase reductase family signature 85 97 6.0E-28 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 PRINTS PR00409 Phthalate dioxygenase reductase family signature 121 135 6.0E-28 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 PRINTS PR00409 Phthalate dioxygenase reductase family signature 156 175 6.0E-28 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 SUPERFAMILY SSF63380 50 145 1.25E-26 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_15705 d64f86be6590dd0bf3d38a11b7ee9af4 343 Gene3D G3DSA:2.40.30.10 45 146 4.4E-27 T 14-10-2018 A4R43_26465 39e22d01d0af3c9e7e098cbf1820d4c8 310 SMART SM00342 224 308 6.9E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_26465 39e22d01d0af3c9e7e098cbf1820d4c8 310 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 277 292 4.2E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_26465 39e22d01d0af3c9e7e098cbf1820d4c8 310 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 292 308 4.2E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_26465 39e22d01d0af3c9e7e098cbf1820d4c8 310 Gene3D G3DSA:1.10.10.60 205 310 3.3E-25 T 14-10-2018 A4R43_26465 39e22d01d0af3c9e7e098cbf1820d4c8 310 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 304 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_26465 39e22d01d0af3c9e7e098cbf1820d4c8 310 SUPERFAMILY SSF46689 258 309 1.48E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_26465 39e22d01d0af3c9e7e098cbf1820d4c8 310 Pfam PF12833 Helix-turn-helix domain 230 309 1.8E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_10265 b88c002215e56767c7b53705b058d1c7 389 SUPERFAMILY SSF53474 99 375 1.29E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_10265 b88c002215e56767c7b53705b058d1c7 389 Gene3D G3DSA:3.40.50.1820 74 379 3.4E-79 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_10265 b88c002215e56767c7b53705b058d1c7 389 Pfam PF00756 Putative esterase 110 369 4.9E-34 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 SMART SM01240 16 488 6.4E-303 T 14-10-2018 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 Gene3D G3DSA:3.20.20.70 7 501 2.5E-207 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 17 488 1.8E-153 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 SUPERFAMILY SSF54631 102 211 8.46E-30 T 14-10-2018 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 17 471 1.3E-180 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 SMART SM00116 105 153 1.3E-7 T 14-10-2018 IPR000644 CBS domain A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 SMART SM00116 166 214 1.2E-6 T 14-10-2018 IPR000644 CBS domain A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 SUPERFAMILY SSF51412 12 492 1.83E-114 T 14-10-2018 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 17 501 82.472 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 Pfam PF00571 CBS domain 158 211 3.8E-7 T 14-10-2018 IPR000644 CBS domain A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 Pfam PF00571 CBS domain 102 150 1.5E-8 T 14-10-2018 IPR000644 CBS domain A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 304 316 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A4R43_34345 4225c3a12e3260fc5aaadbbfd354bd00 502 PIRSF PIRSF000130 8 502 2.1E-198 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A4R43_02345 be5feba51acaf6e4c32bb36c5f902093 85 Gene3D G3DSA:1.10.1200.10 8 85 3.0E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02345 be5feba51acaf6e4c32bb36c5f902093 85 Pfam PF00550 Phosphopantetheine attachment site 11 79 1.7E-8 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_02345 be5feba51acaf6e4c32bb36c5f902093 85 SUPERFAMILY SSF47336 9 83 1.06E-12 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02830 d41cd9335d1cb96f66bbc79d7caae744 759 SUPERFAMILY SSF53706 56 629 2.75E-139 T 14-10-2018 A4R43_02830 d41cd9335d1cb96f66bbc79d7caae744 759 PIRSF PIRSF000144 1 759 0.0 T 14-10-2018 A4R43_02830 d41cd9335d1cb96f66bbc79d7caae744 759 Gene3D G3DSA:3.40.228.10 192 414 5.3E-72 T 14-10-2018 A4R43_02830 d41cd9335d1cb96f66bbc79d7caae744 759 SUPERFAMILY SSF50692 639 757 3.84E-15 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_02830 d41cd9335d1cb96f66bbc79d7caae744 759 Gene3D G3DSA:3.40.50.740 127 580 5.3E-72 T 14-10-2018 A4R43_02830 d41cd9335d1cb96f66bbc79d7caae744 759 Pfam PF01568 Molydopterin dinucleotide binding domain 643 749 1.2E-8 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4R43_02830 d41cd9335d1cb96f66bbc79d7caae744 759 Pfam PF00384 Molybdopterin oxidoreductase 116 414 2.3E-25 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_02830 d41cd9335d1cb96f66bbc79d7caae744 759 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 20 756 2.4E-278 T 14-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 SUPERFAMILY SSF52540 513 790 1.03E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 SMART SM00862 17 97 7.5E-5 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 SUPERFAMILY SSF55073 346 489 2.83E-14 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 Gene3D G3DSA:1.10.10.10 2 100 9.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 Pfam PF03704 Bacterial transcriptional activator domain 104 249 3.0E-47 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 85 9.8E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 Gene3D G3DSA:1.25.40.10 102 278 2.8E-50 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 SUPERFAMILY SSF48452 99 267 2.7E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 Gene3D G3DSA:3.30.70.1230 327 495 1.0E-11 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 SUPERFAMILY SSF46894 4 97 1.64E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 SMART SM01043 104 249 1.1E-50 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_05375 85ae4257331338c9bc905661a9ff53ee 928 Pfam PF13191 AAA ATPase domain 519 703 3.5E-21 T 14-10-2018 A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 PIRSF PIRSF002599 1 67 1.1E-25 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 PRINTS PR00050 Cold shock protein signature 40 58 1.5E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 PRINTS PR00050 Cold shock protein signature 4 19 1.5E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 PRINTS PR00050 Cold shock protein signature 25 34 1.5E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 SUPERFAMILY SSF50249 2 66 9.14E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 SMART SM00357 3 67 1.5E-28 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.1E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_32510 b24d91a2f48a1761633564c9693c9fa0 67 Gene3D G3DSA:2.40.50.140 1 66 1.1E-29 T 14-10-2018 A4R43_00435 4d86afa2cc363e69a382e75970df65d7 567 SUPERFAMILY SSF82549 12 328 7.85E-99 T 14-10-2018 A4R43_00435 4d86afa2cc363e69a382e75970df65d7 567 Gene3D G3DSA:1.25.40.340 357 564 4.2E-51 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_00435 4d86afa2cc363e69a382e75970df65d7 567 SMART SM01120 387 563 3.5E-52 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_00435 4d86afa2cc363e69a382e75970df65d7 567 SUPERFAMILY SSF101473 361 562 4.97E-43 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_00435 4d86afa2cc363e69a382e75970df65d7 567 Gene3D G3DSA:3.30.1180.20 183 330 8.2E-41 T 14-10-2018 A4R43_00435 4d86afa2cc363e69a382e75970df65d7 567 Pfam PF02733 Dak1 domain 18 325 8.5E-103 T 14-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_00435 4d86afa2cc363e69a382e75970df65d7 567 Gene3D G3DSA:3.40.50.10440 13 181 9.4E-51 T 14-10-2018 A4R43_00435 4d86afa2cc363e69a382e75970df65d7 567 Pfam PF02734 DAK2 domain 388 562 1.1E-42 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 Gene3D G3DSA:1.10.510.10 618 795 1.2E-22 T 14-10-2018 A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 538 568 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 SUPERFAMILY SSF56112 269 499 2.63E-18 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 SUPERFAMILY SSF56112 521 796 2.05E-27 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 Gene3D G3DSA:3.30.200.20 508 617 1.2E-22 T 14-10-2018 A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 Pfam PF08378 Nuclease-related domain 30 134 2.9E-8 T 14-10-2018 IPR011528 Nuclease-related domain, NERD A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 SMART SM00220 532 797 4.9E-10 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 Pfam PF00069 Protein kinase domain 265 452 3.3E-9 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 Pfam PF00069 Protein kinase domain 533 787 1.9E-15 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_09265 3272573a7d4a505c8c5b4cd07d3dc345 1448 Gene3D G3DSA:1.10.510.10 272 500 1.9E-17 T 14-10-2018 A4R43_13885 c98b397838837906fde96d25ab1953db 750 SMART SM00636 324 737 7.3E-122 T 14-10-2018 IPR011583 Chitinase II GO:0008061 A4R43_13885 c98b397838837906fde96d25ab1953db 750 SUPERFAMILY SSF49384 35 128 1.12E-12 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A4R43_13885 c98b397838837906fde96d25ab1953db 750 Gene3D G3DSA:3.10.50.10 646 718 2.2E-144 T 14-10-2018 IPR029070 Chitinase insertion domain superfamily A4R43_13885 c98b397838837906fde96d25ab1953db 750 SUPERFAMILY SSF54556 638 709 6.34E-10 T 14-10-2018 IPR029070 Chitinase insertion domain superfamily A4R43_13885 c98b397838837906fde96d25ab1953db 750 SMART SM00637 35 130 3.2E-8 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_13885 c98b397838837906fde96d25ab1953db 750 Gene3D G3DSA:2.60.40.10 231 317 2.0E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_13885 c98b397838837906fde96d25ab1953db 750 Gene3D G3DSA:2.60.40.10 135 223 7.6E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_13885 c98b397838837906fde96d25ab1953db 750 Pfam PF00553 Cellulose binding domain 42 130 2.4E-11 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_13885 c98b397838837906fde96d25ab1953db 750 SMART SM00060 138 212 2.6E-11 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_13885 c98b397838837906fde96d25ab1953db 750 SMART SM00060 233 307 1.2E-9 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_13885 c98b397838837906fde96d25ab1953db 750 SUPERFAMILY SSF49265 136 317 7.59E-27 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_13885 c98b397838837906fde96d25ab1953db 750 Pfam PF00041 Fibronectin type III domain 139 215 3.3E-11 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_13885 c98b397838837906fde96d25ab1953db 750 Pfam PF00041 Fibronectin type III domain 234 303 1.9E-6 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_13885 c98b397838837906fde96d25ab1953db 750 ProSitePatterns PS01095 Chitinases family 18 active site. 494 502 - T 14-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A4R43_13885 c98b397838837906fde96d25ab1953db 750 SUPERFAMILY SSF51445 320 738 1.02E-87 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_13885 c98b397838837906fde96d25ab1953db 750 Gene3D G3DSA:2.60.40.290 36 134 1.5E-18 T 14-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A4R43_13885 c98b397838837906fde96d25ab1953db 750 Gene3D G3DSA:3.20.20.80 327 744 2.2E-144 T 14-10-2018 A4R43_13885 c98b397838837906fde96d25ab1953db 750 Pfam PF00704 Glycosyl hydrolases family 18 327 737 9.3E-78 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A4R43_33865 ef47bbcd30aed2b1ec44b910015eacc5 137 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 17 119 9.5E-46 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33865 ef47bbcd30aed2b1ec44b910015eacc5 137 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 13 122 28.482 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33865 ef47bbcd30aed2b1ec44b910015eacc5 137 Pfam PF00237 Ribosomal protein L22p/L17e 17 119 3.7E-34 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A4R43_33865 ef47bbcd30aed2b1ec44b910015eacc5 137 SUPERFAMILY SSF54843 12 122 1.96E-41 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_33865 ef47bbcd30aed2b1ec44b910015eacc5 137 ProSitePatterns PS00464 Ribosomal protein L22 signature. 95 119 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33865 ef47bbcd30aed2b1ec44b910015eacc5 137 Gene3D G3DSA:3.90.470.10 11 136 1.3E-47 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_37930 8c606a85c88b59fff42044f7dc2877a7 137 SUPERFAMILY SSF55298 7 131 9.74E-22 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_37930 8c606a85c88b59fff42044f7dc2877a7 137 Gene3D G3DSA:3.30.1330.40 3 132 1.0E-20 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_37930 8c606a85c88b59fff42044f7dc2877a7 137 Pfam PF01042 Endoribonuclease L-PSP 16 130 6.4E-14 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4R43_19600 40b4179ed766905dd8a83589873abf0e 233 Pfam PF09339 IclR helix-turn-helix domain 10 56 5.2E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_19600 40b4179ed766905dd8a83589873abf0e 233 Gene3D G3DSA:3.30.450.40 71 232 9.0E-39 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_19600 40b4179ed766905dd8a83589873abf0e 233 Gene3D G3DSA:1.10.10.10 2 70 1.5E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19600 40b4179ed766905dd8a83589873abf0e 233 SUPERFAMILY SSF55781 62 233 1.5E-37 T 14-10-2018 A4R43_19600 40b4179ed766905dd8a83589873abf0e 233 Pfam PF01614 Bacterial transcriptional regulator 124 230 3.1E-17 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_19600 40b4179ed766905dd8a83589873abf0e 233 SMART SM00346 7 92 3.9E-23 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_19600 40b4179ed766905dd8a83589873abf0e 233 SUPERFAMILY SSF46785 7 72 1.58E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05400 0de806d828f00b6ea24c258c5a36aad6 130 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 10 125 4.0E-34 T 14-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 SUPERFAMILY SSF52540 183 455 3.26E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 Pfam PF00271 Helicase conserved C-terminal domain 491 606 3.5E-18 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 Pfam PF17191 RecG wedge domain 12 173 1.9E-17 T 14-10-2018 IPR033454 RecG, wedge domain A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 SUPERFAMILY SSF52540 397 616 1.11E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 Gene3D G3DSA:3.40.50.300 186 457 1.8E-79 T 14-10-2018 A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 Gene3D G3DSA:3.40.50.300 466 648 5.4E-52 T 14-10-2018 A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 SMART SM00487 263 467 2.9E-30 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 SUPERFAMILY SSF50249 12 176 4.11E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 Pfam PF00270 DEAD/DEAH box helicase 287 443 3.2E-18 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 Gene3D G3DSA:2.40.50.140 43 141 3.9E-20 T 14-10-2018 A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 24 682 4.2E-204 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 A4R43_19490 ba74b438bfaf2ed17b332cc691b127fa 719 SMART SM00490 522 607 1.4E-21 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_11525 0ec93e255c3bdc3bdbc7982aab9d12c6 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 169 6.5E-27 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_11525 0ec93e255c3bdc3bdbc7982aab9d12c6 183 Gene3D G3DSA:1.10.1740.10 3 86 7.9E-19 T 14-10-2018 A4R43_11525 0ec93e255c3bdc3bdbc7982aab9d12c6 183 Pfam PF04542 Sigma-70 region 2 22 88 9.2E-19 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_11525 0ec93e255c3bdc3bdbc7982aab9d12c6 183 SUPERFAMILY SSF88946 13 103 2.9E-21 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_11525 0ec93e255c3bdc3bdbc7982aab9d12c6 183 SUPERFAMILY SSF88659 108 169 1.29E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_11525 0ec93e255c3bdc3bdbc7982aab9d12c6 183 Pfam PF04545 Sigma-70, region 4 120 169 5.2E-13 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_11525 0ec93e255c3bdc3bdbc7982aab9d12c6 183 Gene3D G3DSA:1.10.10.10 106 175 1.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19825 7a678add0b9e34d4012d7992d634a623 259 Pfam PF00005 ABC transporter 26 167 5.2E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_19825 7a678add0b9e34d4012d7992d634a623 259 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_19825 7a678add0b9e34d4012d7992d634a623 259 Gene3D G3DSA:3.40.50.300 2 236 2.0E-62 T 14-10-2018 A4R43_19825 7a678add0b9e34d4012d7992d634a623 259 SMART SM00382 35 216 8.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_19825 7a678add0b9e34d4012d7992d634a623 259 SUPERFAMILY SSF52540 7 229 1.15E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13040 743b93bd49502b86750e50fa51a14489 225 SUPERFAMILY SSF160104 3 224 1.05E-35 T 14-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A4R43_13040 743b93bd49502b86750e50fa51a14489 225 Pfam PF06314 Acetoacetate decarboxylase (ADC) 8 210 2.7E-30 T 14-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A4R43_13040 743b93bd49502b86750e50fa51a14489 225 Gene3D G3DSA:2.40.400.10 8 225 1.4E-16 T 14-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A4R43_19560 2610fd13fb8e77516212cfb334910fd3 232 SUPERFAMILY SSF69593 17 219 1.7E-42 T 14-10-2018 A4R43_19560 2610fd13fb8e77516212cfb334910fd3 232 Pfam PF01553 Acyltransferase 29 155 8.7E-24 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_19560 2610fd13fb8e77516212cfb334910fd3 232 SMART SM00563 41 159 2.6E-33 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 SMART SM00387 371 483 5.5E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 SMART SM00304 195 247 1.2E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 481 5.8E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 6.9E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 460 6.9E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 6.9E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 Gene3D G3DSA:1.10.287.130 251 331 5.1E-14 T 14-10-2018 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 Pfam PF00672 HAMP domain 195 243 2.4E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 Gene3D G3DSA:3.30.565.10 332 481 4.3E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 Gene3D G3DSA:1.20.1480.50 158 250 1.7E-5 T 14-10-2018 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 Gene3D G3DSA:1.20.1440.210 41 151 2.1E-10 T 14-10-2018 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 SUPERFAMILY SSF55874 319 483 2.23E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 SUPERFAMILY SSF47384 248 328 7.85E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 SMART SM00388 262 330 1.3E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 Pfam PF05227 CHASE3 domain 39 152 7.3E-14 T 14-10-2018 IPR007891 CHASE3 A4R43_15200 7b2196c48e1510f086253fcbc7e9ed40 496 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 328 2.3E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_18580 f0b198774b4cc60deb7aa524c4537521 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 12 422 3.4E-99 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A4R43_18580 f0b198774b4cc60deb7aa524c4537521 436 TIGRFAM TIGR03173 pbuX: xanthine permease 18 423 1.2E-142 T 14-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 A4R43_18580 f0b198774b4cc60deb7aa524c4537521 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 339 359 - T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A4R43_18580 f0b198774b4cc60deb7aa524c4537521 436 Pfam PF00860 Permease family 12 390 3.1E-89 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A4R43_21245 490fc6a6e4cf20af4c88f63cf4de4284 169 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 1 167 9.7E-40 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_21245 490fc6a6e4cf20af4c88f63cf4de4284 169 Gene3D G3DSA:1.20.120.450 1 58 1.1E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_21245 490fc6a6e4cf20af4c88f63cf4de4284 169 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 2 111 3.0E-12 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_21245 490fc6a6e4cf20af4c88f63cf4de4284 169 SUPERFAMILY SSF109854 2 117 7.94E-15 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_21245 490fc6a6e4cf20af4c88f63cf4de4284 169 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 1 167 5.7E-22 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_26540 0fa122e5acf662bbba6937d27c437afe 82 Pfam PF02597 ThiS family 2 82 1.8E-13 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A4R43_26540 0fa122e5acf662bbba6937d27c437afe 82 Gene3D G3DSA:3.10.20.30 1 82 9.3E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_26540 0fa122e5acf662bbba6937d27c437afe 82 SUPERFAMILY SSF54285 3 82 2.62E-16 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 51 758 0.0 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 SUPERFAMILY SSF48113 454 755 1.47E-110 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 SUPERFAMILY SSF48113 52 453 4.27E-145 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 282 292 - T 14-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 Pfam PF00141 Peroxidase 113 419 1.6E-46 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 Pfam PF00141 Peroxidase 428 729 2.2E-38 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00458 Haem peroxidase superfamily signature 197 209 6.0E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00458 Haem peroxidase superfamily signature 179 196 6.0E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00458 Haem peroxidase superfamily signature 282 297 6.0E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00458 Haem peroxidase superfamily signature 342 357 6.0E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00458 Haem peroxidase superfamily signature 119 133 6.0E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 96 121 1.7E-46 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 81 94 1.7E-46 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 290 313 1.7E-46 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 503 529 1.7E-46 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 55 77 1.7E-46 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 Gene3D G3DSA:1.10.420.20 219 421 1.5E-208 T 14-10-2018 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 Gene3D G3DSA:1.10.420.10 609 731 4.2E-146 T 14-10-2018 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 ProSitePatterns PS00436 Peroxidases active site signature. 119 130 - T 14-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 Gene3D G3DSA:1.10.520.10 456 755 4.2E-146 T 14-10-2018 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 Hamap MF_01961 Catalase-peroxidase [katG]. 17 756 40.98 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_00875 141c86a4149f1e6dc14ca795784bde93 758 Gene3D G3DSA:1.10.520.10 52 453 1.5E-208 T 14-10-2018 A4R43_23375 9d51df7684a0319344a0c2a7ffd88728 127 Pfam PF00293 NUDIX domain 5 121 2.2E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_23375 9d51df7684a0319344a0c2a7ffd88728 127 SUPERFAMILY SSF55811 4 125 3.25E-25 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_23375 9d51df7684a0319344a0c2a7ffd88728 127 Gene3D G3DSA:3.90.79.10 1 125 3.9E-29 T 14-10-2018 A4R43_35960 dbcd1fc07af122fa86db4de523a33856 1090 Gene3D G3DSA:3.40.50.300 235 379 5.2E-28 T 14-10-2018 A4R43_35960 dbcd1fc07af122fa86db4de523a33856 1090 Gene3D G3DSA:3.40.50.300 410 508 3.3E-15 T 14-10-2018 A4R43_35960 dbcd1fc07af122fa86db4de523a33856 1090 SUPERFAMILY SSF52980 926 1062 1.61E-6 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4R43_35960 dbcd1fc07af122fa86db4de523a33856 1090 Pfam PF12705 PD-(D/E)XK nuclease superfamily 924 1065 6.7E-10 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A4R43_35960 dbcd1fc07af122fa86db4de523a33856 1090 SUPERFAMILY SSF52540 21 791 8.36E-103 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35960 dbcd1fc07af122fa86db4de523a33856 1090 Pfam PF00580 UvrD/REP helicase N-terminal domain 24 343 1.8E-45 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A4R43_35960 dbcd1fc07af122fa86db4de523a33856 1090 Pfam PF13361 UvrD-like helicase C-terminal domain 401 764 5.8E-24 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4R43_35960 dbcd1fc07af122fa86db4de523a33856 1090 Gene3D G3DSA:3.40.50.300 19 198 2.6E-30 T 14-10-2018 A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 165 5.3E-22 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 2 290 1.2E-80 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 SUPERFAMILY SSF54427 180 289 7.76E-8 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 SUPERFAMILY SSF88659 108 166 1.35E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 Gene3D G3DSA:1.10.10.10 109 173 3.0E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 Pfam PF08281 Sigma-70, region 4 111 164 2.8E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 Pfam PF04542 Sigma-70 region 2 11 75 1.6E-19 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 Gene3D G3DSA:3.10.450.50 177 291 2.5E-8 T 14-10-2018 A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 Gene3D G3DSA:1.10.1740.10 1 76 6.4E-21 T 14-10-2018 A4R43_22530 774b32b7247a925648b36c1b4fad4090 292 SUPERFAMILY SSF88946 4 78 1.18E-21 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 SUPERFAMILY SSF103190 37 154 2.55E-16 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 Gene3D G3DSA:3.30.450.20 192 301 3.3E-19 T 14-10-2018 A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 Pfam PF17203 Single cache domain 3 37 152 1.3E-20 T 14-10-2018 IPR033463 Single cache domain 3 A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 Gene3D G3DSA:3.30.565.10 368 533 1.6E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 SUPERFAMILY SSF55874 408 513 1.28E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 SMART SM00091 206 271 0.0028 T 14-10-2018 IPR000014 PAS domain A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 312 355 1.8E-10 T 14-10-2018 IPR039506 SpoOB, alpha-helical domain A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 Gene3D G3DSA:3.30.450.20 30 156 1.8E-15 T 14-10-2018 A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 SUPERFAMILY SSF55890 316 357 1.96E-10 T 14-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 SMART SM00387 405 533 5.4E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_31955 3d51db50ee074c48d512bbba8127d012 538 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 408 513 6.6E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_32455 6dab7f411d4c2358080384bd7c2d0775 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 112 5.9E-5 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_32455 6dab7f411d4c2358080384bd7c2d0775 368 SUPERFAMILY SSF51604 100 365 1.1E-54 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_32455 6dab7f411d4c2358080384bd7c2d0775 368 SMART SM00922 130 237 3.1E-18 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_32455 6dab7f411d4c2358080384bd7c2d0775 368 Pfam PF13378 Enolase C-terminal domain-like 136 360 3.7E-53 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_32455 6dab7f411d4c2358080384bd7c2d0775 368 Gene3D G3DSA:3.30.390.10 1 108 1.6E-18 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_32455 6dab7f411d4c2358080384bd7c2d0775 368 Gene3D G3DSA:3.20.20.120 109 366 2.9E-65 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_32455 6dab7f411d4c2358080384bd7c2d0775 368 SUPERFAMILY SSF54826 1 112 2.47E-17 T 14-10-2018 A4R43_25355 51f2222b39b70eb94fa75bccf5ed3b07 682 SUPERFAMILY SSF82866 99 327 1.31E-26 T 14-10-2018 A4R43_25355 51f2222b39b70eb94fa75bccf5ed3b07 682 Gene3D G3DSA:1.20.1640.10 147 332 3.9E-6 T 14-10-2018 A4R43_25355 51f2222b39b70eb94fa75bccf5ed3b07 682 Gene3D G3DSA:3.30.70.1440 450 490 2.0E-6 T 14-10-2018 A4R43_25355 51f2222b39b70eb94fa75bccf5ed3b07 682 Gene3D G3DSA:1.20.1640.10 491 598 2.0E-6 T 14-10-2018 A4R43_25355 51f2222b39b70eb94fa75bccf5ed3b07 682 Pfam PF03176 MMPL family 86 352 9.6E-37 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_25355 51f2222b39b70eb94fa75bccf5ed3b07 682 Pfam PF03176 MMPL family 415 665 6.1E-33 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_25355 51f2222b39b70eb94fa75bccf5ed3b07 682 SUPERFAMILY SSF82866 445 665 1.44E-31 T 14-10-2018 A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 Pfam PF01037 Lrp/AsnC ligand binding domain 70 141 6.0E-12 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 SUPERFAMILY SSF54909 66 144 9.79E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 Gene3D G3DSA:3.30.70.920 58 138 2.0E-17 T 14-10-2018 A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 SUPERFAMILY SSF46785 5 64 5.58E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 Gene3D G3DSA:1.10.10.10 6 57 1.4E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 SMART SM00344 5 112 3.4E-35 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_10675 e35cda5305b8a13d99d577fd911c908f 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 52 1.2E-15 T 14-10-2018 A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 Gene3D G3DSA:3.40.50.300 255 509 2.5E-42 T 14-10-2018 A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 SMART SM00382 34 223 4.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 SMART SM00382 292 487 0.5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 Gene3D G3DSA:3.40.50.300 3 254 2.0E-61 T 14-10-2018 A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 SUPERFAMILY SSF52540 8 235 3.01E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 ProSitePatterns PS00211 ABC transporters family signature. 412 426 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 Pfam PF00005 ABC transporter 285 439 4.5E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 SUPERFAMILY SSF52540 263 498 4.14E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14640 2373a9fb315ec78eafe2348d06334824 518 Pfam PF00005 ABC transporter 26 175 2.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 Gene3D G3DSA:3.10.20.30 446 517 3.6E-31 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 Pfam PF02824 TGS domain 453 512 1.8E-22 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 SMART SM00471 106 216 4.1E-12 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 Pfam PF13291 ACT domain 709 785 1.4E-16 T 14-10-2018 IPR002912 ACT domain A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 Pfam PF04607 Region found in RelA / SpoT proteins 298 407 6.7E-36 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 91 785 9.8E-264 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 Pfam PF13328 HD domain 91 238 6.8E-49 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 SMART SM00954 298 408 3.5E-60 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 SUPERFAMILY SSF81301 243 457 8.66E-60 T 14-10-2018 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 Gene3D G3DSA:3.30.460.10 256 388 1.6E-44 T 14-10-2018 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 Gene3D G3DSA:3.30.70.260 709 789 1.9E-16 T 14-10-2018 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 SUPERFAMILY SSF55021 708 787 6.66E-14 T 14-10-2018 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 Gene3D G3DSA:1.10.3210.10 62 254 9.1E-79 T 14-10-2018 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 SUPERFAMILY SSF81271 440 512 4.14E-21 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4R43_04355 907fcbd1a0dd1e31472a7049fc4cd2c1 790 SUPERFAMILY SSF109604 67 253 4.71E-71 T 14-10-2018 A4R43_14180 0579f9dc2ee1a7f29f6822680e22b0b6 329 Pfam PF13614 AAA domain 79 255 1.2E-61 T 14-10-2018 IPR025669 AAA domain A4R43_14180 0579f9dc2ee1a7f29f6822680e22b0b6 329 SUPERFAMILY SSF52540 78 328 1.0E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14180 0579f9dc2ee1a7f29f6822680e22b0b6 329 Gene3D G3DSA:3.40.50.300 72 329 3.3E-82 T 14-10-2018 A4R43_41410 7634fa496d42cc0ac3a7e3bd40cd3809 319 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 36.103 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A4R43_41410 7634fa496d42cc0ac3a7e3bd40cd3809 319 Gene3D G3DSA:3.40.50.150 7 310 7.8E-93 T 14-10-2018 A4R43_41410 7634fa496d42cc0ac3a7e3bd40cd3809 319 SUPERFAMILY SSF81799 118 219 8.5E-34 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 A4R43_41410 7634fa496d42cc0ac3a7e3bd40cd3809 319 Gene3D G3DSA:1.10.150.170 116 221 7.8E-93 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 A4R43_41410 7634fa496d42cc0ac3a7e3bd40cd3809 319 PIRSF PIRSF004486 3 315 7.2E-95 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A4R43_41410 7634fa496d42cc0ac3a7e3bd40cd3809 319 Pfam PF01795 MraW methylase family 6 313 5.2E-109 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A4R43_41410 7634fa496d42cc0ac3a7e3bd40cd3809 319 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 6 313 4.4E-89 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A4R43_41410 7634fa496d42cc0ac3a7e3bd40cd3809 319 SUPERFAMILY SSF53335 7 314 5.99E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_05740 dd190ea02a0509b0970b19251b2e58b2 117 SUPERFAMILY SSF52091 9 114 1.45E-17 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_05740 dd190ea02a0509b0970b19251b2e58b2 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 9 112 2.3E-16 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_05740 dd190ea02a0509b0970b19251b2e58b2 117 Pfam PF13466 STAS domain 22 100 9.0E-8 T 14-10-2018 IPR002645 STAS domain A4R43_05740 dd190ea02a0509b0970b19251b2e58b2 117 Gene3D G3DSA:3.30.750.24 6 116 7.3E-27 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_05040 da5a98be0630bdf408e51e8b7608ba4b 231 Pfam PF13412 Winged helix-turn-helix DNA-binding 17 52 8.7E-7 T 14-10-2018 A4R43_05040 da5a98be0630bdf408e51e8b7608ba4b 231 SUPERFAMILY SSF46785 9 195 1.8E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05040 da5a98be0630bdf408e51e8b7608ba4b 231 Gene3D G3DSA:1.10.10.10 6 92 1.4E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_16585 a715963feac4956261f894d5cd934956 488 Gene3D G3DSA:3.40.1190.10 106 336 8.0E-70 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_16585 a715963feac4956261f894d5cd934956 488 Pfam PF02875 Mur ligase family, glutamate ligase domain 342 427 1.9E-22 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4R43_16585 a715963feac4956261f894d5cd934956 488 Gene3D G3DSA:3.90.190.20 339 484 1.7E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_16585 a715963feac4956261f894d5cd934956 488 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 481 31.872 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_16585 a715963feac4956261f894d5cd934956 488 SUPERFAMILY SSF53623 127 335 1.44E-52 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_16585 a715963feac4956261f894d5cd934956 488 Pfam PF08245 Mur ligase middle domain 132 319 6.4E-41 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4R43_16585 a715963feac4956261f894d5cd934956 488 SUPERFAMILY SSF63418 2 81 3.92E-18 T 14-10-2018 IPR035911 MurE/MurF, N-terminal A4R43_16585 a715963feac4956261f894d5cd934956 488 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 479 6.3E-127 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_16585 a715963feac4956261f894d5cd934956 488 Gene3D G3DSA:3.40.1390.10 1 81 3.8E-24 T 14-10-2018 A4R43_16585 a715963feac4956261f894d5cd934956 488 Pfam PF01225 Mur ligase family, catalytic domain 30 74 1.8E-8 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4R43_16585 a715963feac4956261f894d5cd934956 488 SUPERFAMILY SSF53244 342 479 5.49E-33 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_31895 163cf9ee6af67f9e03a3cbc42e057973 273 Gene3D G3DSA:3.20.20.80 66 273 2.5E-77 T 14-10-2018 A4R43_31895 163cf9ee6af67f9e03a3cbc42e057973 273 Pfam PF01183 Glycosyl hydrolases family 25 71 255 2.2E-45 T 14-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 A4R43_31895 163cf9ee6af67f9e03a3cbc42e057973 273 SMART SM00641 67 177 3.5E-34 T 14-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup A4R43_31895 163cf9ee6af67f9e03a3cbc42e057973 273 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 71 104 - T 14-10-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 A4R43_31895 163cf9ee6af67f9e03a3cbc42e057973 273 SUPERFAMILY SSF51445 67 271 4.77E-61 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_21960 43abc8232dfccc95dd1af8f1e974959a 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 1.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_21960 43abc8232dfccc95dd1af8f1e974959a 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 1.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_21960 43abc8232dfccc95dd1af8f1e974959a 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_21960 43abc8232dfccc95dd1af8f1e974959a 153 Pfam PF12802 MarR family 42 91 7.6E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_21960 43abc8232dfccc95dd1af8f1e974959a 153 SUPERFAMILY SSF46785 5 138 2.18E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_21960 43abc8232dfccc95dd1af8f1e974959a 153 SMART SM00347 26 126 2.7E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_21960 43abc8232dfccc95dd1af8f1e974959a 153 Gene3D G3DSA:1.10.10.10 3 143 1.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13060 31d8fa299fb4a1e85868d44b06b1f3e3 220 Gene3D G3DSA:1.10.10.60 12 71 3.7E-12 T 14-10-2018 A4R43_13060 31d8fa299fb4a1e85868d44b06b1f3e3 220 SUPERFAMILY SSF48498 101 202 1.57E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_13060 31d8fa299fb4a1e85868d44b06b1f3e3 220 Gene3D G3DSA:1.10.357.10 72 209 5.6E-14 T 14-10-2018 A4R43_13060 31d8fa299fb4a1e85868d44b06b1f3e3 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 2.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13060 31d8fa299fb4a1e85868d44b06b1f3e3 220 SUPERFAMILY SSF46689 21 94 9.23E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03775 e82a672f1bb3f1d569cb366bf2782254 275 Gene3D G3DSA:1.10.3720.10 76 272 4.3E-32 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_03775 e82a672f1bb3f1d569cb366bf2782254 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 271 9.6E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_03775 e82a672f1bb3f1d569cb366bf2782254 275 SUPERFAMILY SSF161098 78 262 5.1E-34 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_03775 e82a672f1bb3f1d569cb366bf2782254 275 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 26 271 2.9E-82 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 A4R43_03800 577d2612df961b2c9d4daa54cfb462ae 195 SUPERFAMILY SSF48498 97 187 2.85E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_03800 577d2612df961b2c9d4daa54cfb462ae 195 SUPERFAMILY SSF46689 10 81 1.89E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03800 577d2612df961b2c9d4daa54cfb462ae 195 Gene3D G3DSA:1.10.357.10 4 190 1.6E-44 T 14-10-2018 A4R43_03800 577d2612df961b2c9d4daa54cfb462ae 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 3.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 SMART SM00636 43 308 2.3E-55 T 14-10-2018 IPR011583 Chitinase II GO:0008061 A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 Gene3D G3DSA:2.80.10.50 414 452 7.2E-9 T 14-10-2018 A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 ProSitePatterns PS01095 Chitinases family 18 active site. 144 152 - T 14-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 Gene3D G3DSA:2.80.10.50 322 413 1.3E-28 T 14-10-2018 A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 Pfam PF00704 Glycosyl hydrolases family 18 45 308 3.6E-49 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 SUPERFAMILY SSF50370 332 450 3.38E-36 T 14-10-2018 IPR035992 Ricin B-like lectins A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 SUPERFAMILY SSF51445 40 325 2.55E-62 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 Gene3D G3DSA:3.20.20.80 59 311 5.7E-69 T 14-10-2018 A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 Pfam PF00652 Ricin-type beta-trefoil lectin domain 329 448 1.7E-25 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 Gene3D G3DSA:3.40.5.30 246 280 5.7E-69 T 14-10-2018 A4R43_13575 f0c84ede2537a277d0dba2b7e4a96e92 452 SMART SM00458 327 451 1.8E-23 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 17 489 3.7E-144 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 13 482 48.469 T 14-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 SMART SM00997 248 410 9.2E-109 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 Gene3D G3DSA:3.40.50.1480 20 490 2.7E-237 T 14-10-2018 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 248 410 4.5E-81 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 SUPERFAMILY SSF52283 16 490 7.37E-113 T 14-10-2018 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 270 286 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 SUPERFAMILY SSF51735 248 410 7.38E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 89 103 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 18 482 6.9E-194 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 Gene3D G3DSA:3.40.50.720 251 411 2.7E-237 T 14-10-2018 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 SMART SM00996 17 489 0.0 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_23245 feabb78766b60b56ce0fddcab39bba47 490 PIRSF PIRSF001109 4 490 9.5E-191 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_16105 8459903055826d7e478baace3c4e1706 330 SUPERFAMILY SSF46689 270 320 7.17E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_16105 8459903055826d7e478baace3c4e1706 330 SMART SM00342 233 316 1.7E-28 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_16105 8459903055826d7e478baace3c4e1706 330 Pfam PF12833 Helix-turn-helix domain 239 317 4.2E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_16105 8459903055826d7e478baace3c4e1706 330 Pfam PF01965 DJ-1/PfpI family 103 177 3.5E-10 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_16105 8459903055826d7e478baace3c4e1706 330 Gene3D G3DSA:3.40.50.880 3 214 1.6E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_16105 8459903055826d7e478baace3c4e1706 330 SUPERFAMILY SSF46689 221 267 2.06E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_16105 8459903055826d7e478baace3c4e1706 330 Gene3D G3DSA:1.10.10.60 218 321 2.6E-27 T 14-10-2018 A4R43_16105 8459903055826d7e478baace3c4e1706 330 SUPERFAMILY SSF52317 7 199 7.2E-41 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_05995 db542ad4864653160bf37077a25606b8 294 Gene3D G3DSA:3.40.50.720 1 162 1.9E-53 T 14-10-2018 A4R43_05995 db542ad4864653160bf37077a25606b8 294 SUPERFAMILY SSF51735 2 163 2.56E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05995 db542ad4864653160bf37077a25606b8 294 SUPERFAMILY SSF48179 163 287 1.59E-35 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_05995 db542ad4864653160bf37077a25606b8 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 159 1.3E-50 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_05995 db542ad4864653160bf37077a25606b8 294 Gene3D G3DSA:1.10.1040.10 163 292 4.0E-38 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_05995 db542ad4864653160bf37077a25606b8 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 6.8E-37 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A4R43_05995 db542ad4864653160bf37077a25606b8 294 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 290 1.2E-106 T 14-10-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 A4R43_05995 db542ad4864653160bf37077a25606b8 294 PIRSF PIRSF000103 1 294 7.1E-77 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_05995 db542ad4864653160bf37077a25606b8 294 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_05085 2b43e2d9fa33f0ef6488f3d341a7876b 648 Pfam PF03109 ABC1 family 207 323 3.6E-32 T 14-10-2018 IPR004147 UbiB domain A4R43_05085 2b43e2d9fa33f0ef6488f3d341a7876b 648 Gene3D G3DSA:1.10.510.10 341 405 2.6E-5 T 14-10-2018 A4R43_05085 2b43e2d9fa33f0ef6488f3d341a7876b 648 Gene3D G3DSA:3.30.200.20 310 340 2.6E-5 T 14-10-2018 A4R43_05085 2b43e2d9fa33f0ef6488f3d341a7876b 648 SUPERFAMILY SSF56112 189 437 3.13E-27 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_21125 fa55cd3e1891463104ba4a0598404b84 303 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_21125 fa55cd3e1891463104ba4a0598404b84 303 SMART SM00382 29 232 2.5E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_21125 fa55cd3e1891463104ba4a0598404b84 303 Pfam PF00005 ABC transporter 21 159 2.5E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_21125 fa55cd3e1891463104ba4a0598404b84 303 SUPERFAMILY SSF52540 4 228 6.3E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21125 fa55cd3e1891463104ba4a0598404b84 303 Gene3D G3DSA:3.40.50.300 2 249 1.1E-54 T 14-10-2018 A4R43_28845 99db9aab0b950db7a0eac18636dde419 457 Pfam PF13701 Transposase DDE domain group 1 6 447 2.1E-27 T 14-10-2018 IPR025668 Transposase DDE domain A4R43_27520 99db9aab0b950db7a0eac18636dde419 457 Pfam PF13701 Transposase DDE domain group 1 6 447 2.1E-27 T 14-10-2018 IPR025668 Transposase DDE domain A4R43_26560 99db9aab0b950db7a0eac18636dde419 457 Pfam PF13701 Transposase DDE domain group 1 6 447 2.1E-27 T 14-10-2018 IPR025668 Transposase DDE domain A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 Gene3D G3DSA:3.40.47.10 133 382 3.5E-121 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 PIRSF PIRSF000429 1 391 1.3E-120 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 SUPERFAMILY SSF53901 268 388 5.54E-38 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 SUPERFAMILY SSF53901 4 264 1.81E-58 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 Pfam PF02803 Thiolase, C-terminal domain 269 388 8.2E-36 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 Gene3D G3DSA:3.40.47.10 5 270 3.5E-121 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 388 6.3E-125 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_13890 28ee0dc989ee79db16072942b1c6d601 396 Pfam PF00108 Thiolase, N-terminal domain 4 257 1.8E-55 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_39465 942caea2396aee97f93d903d5af711aa 321 SUPERFAMILY SSF50129 12 156 3.93E-31 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_39465 942caea2396aee97f93d903d5af711aa 321 Gene3D G3DSA:3.40.50.720 137 269 3.4E-75 T 14-10-2018 A4R43_39465 942caea2396aee97f93d903d5af711aa 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 123 9.1E-6 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_39465 942caea2396aee97f93d903d5af711aa 321 Gene3D G3DSA:3.90.180.10 20 312 3.4E-75 T 14-10-2018 A4R43_39465 942caea2396aee97f93d903d5af711aa 321 SUPERFAMILY SSF51735 128 289 1.04E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_39465 942caea2396aee97f93d903d5af711aa 321 SMART SM00829 13 319 1.8E-13 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_39465 942caea2396aee97f93d903d5af711aa 321 Pfam PF00107 Zinc-binding dehydrogenase 167 281 7.3E-20 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 SMART SM00957 3 381 1.1E-280 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 Hamap MF_01382 Protein translocase subunit SecA [secA]. 2 829 19.93 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 SMART SM00958 225 337 1.6E-62 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 Gene3D G3DSA:3.90.1440.10 226 347 7.0E-182 T 14-10-2018 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 SUPERFAMILY SSF52540 395 612 9.82E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23205 38445fd1171e17462b57de08444d6a53 943 Gene3D G3DSA:1.10.3060.10 615 830 2.1E-73 T 14-10-2018 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 Gene3D G3DSA:3.40.50.300 19 394 7.0E-182 T 14-10-2018 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 25 814 0.0 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 SUPERFAMILY SSF52540 8 394 8.15E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23205 38445fd1171e17462b57de08444d6a53 943 SUPERFAMILY SSF81886 614 833 1.31E-72 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily A4R43_23205 38445fd1171e17462b57de08444d6a53 943 Pfam PF01043 SecA preprotein cross-linking domain 229 337 8.2E-36 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 PRINTS PR00906 SecA protein signature 167 187 3.2E-71 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 PRINTS PR00906 SecA protein signature 60 84 3.2E-71 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 PRINTS PR00906 SecA protein signature 114 124 3.2E-71 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 PRINTS PR00906 SecA protein signature 98 112 3.2E-71 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 PRINTS PR00906 SecA protein signature 392 405 3.2E-71 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 PRINTS PR00906 SecA protein signature 355 372 3.2E-71 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 PRINTS PR00906 SecA protein signature 318 340 3.2E-71 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 Pfam PF07516 SecA Wing and Scaffold domain 611 826 1.5E-67 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 SUPERFAMILY SSF81767 224 347 1.57E-43 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 Pfam PF07517 SecA DEAD-like domain 6 380 2.5E-129 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4R43_23205 38445fd1171e17462b57de08444d6a53 943 Gene3D G3DSA:3.40.50.300 396 613 2.5E-91 T 14-10-2018 A4R43_13245 dcbfbcd2b4ae556feae9d4a00e27cf7b 335 SUPERFAMILY SSF51735 145 302 1.18E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13245 dcbfbcd2b4ae556feae9d4a00e27cf7b 335 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_13245 dcbfbcd2b4ae556feae9d4a00e27cf7b 335 Gene3D G3DSA:3.90.180.10 13 313 3.8E-70 T 14-10-2018 A4R43_13245 dcbfbcd2b4ae556feae9d4a00e27cf7b 335 Gene3D G3DSA:3.40.50.720 156 279 3.8E-70 T 14-10-2018 A4R43_13245 dcbfbcd2b4ae556feae9d4a00e27cf7b 335 SUPERFAMILY SSF50129 1 177 3.3E-43 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_13245 dcbfbcd2b4ae556feae9d4a00e27cf7b 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 136 1.2E-24 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 14-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 Pfam PF00795 Carbon-nitrogen hydrolase 5 251 6.0E-33 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 PIRSF PIRSF006630 1 572 2.9E-201 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 Gene3D G3DSA:3.40.50.620 294 572 5.8E-107 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 SUPERFAMILY SSF52402 290 552 7.89E-71 T 14-10-2018 A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 Gene3D G3DSA:3.60.110.10 2 291 5.2E-100 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 4 570 29.143 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 Pfam PF02540 NAD synthase 297 544 3.1E-68 T 14-10-2018 IPR022310 NAD/GMP synthase A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 SUPERFAMILY SSF56317 1 251 4.84E-62 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_22190 b63c5e06fccbc41c001635efecc21f12 572 TIGRFAM TIGR00552 nadE: NAD+ synthetase 304 550 5.8E-56 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A4R43_17915 970a27f543d67fa564a6b35e9ab8f6f6 393 Gene3D G3DSA:2.60.40.3780 33 128 4.8E-22 T 14-10-2018 A4R43_17915 970a27f543d67fa564a6b35e9ab8f6f6 393 Pfam PF03734 L,D-transpeptidase catalytic domain 247 362 1.0E-15 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4R43_17915 970a27f543d67fa564a6b35e9ab8f6f6 393 SUPERFAMILY SSF141523 236 362 2.09E-26 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_17915 970a27f543d67fa564a6b35e9ab8f6f6 393 Gene3D G3DSA:2.60.40.3710 145 389 3.3E-94 T 14-10-2018 A4R43_17915 970a27f543d67fa564a6b35e9ab8f6f6 393 Gene3D G3DSA:2.40.440.10 236 377 3.3E-94 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_29515 d7de8bf9c2a1d9669069e6e043f615a4 231 SUPERFAMILY SSF102114 33 194 3.66E-16 T 14-10-2018 A4R43_29515 d7de8bf9c2a1d9669069e6e043f615a4 231 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 12 231 34.719 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A4R43_29515 d7de8bf9c2a1d9669069e6e043f615a4 231 Gene3D G3DSA:3.20.20.70 13 230 5.0E-36 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_29515 d7de8bf9c2a1d9669069e6e043f615a4 231 Pfam PF13353 4Fe-4S single cluster domain 24 144 3.9E-10 T 14-10-2018 A4R43_29515 d7de8bf9c2a1d9669069e6e043f615a4 231 PIRSF PIRSF000370 11 231 2.8E-43 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A4R43_29515 d7de8bf9c2a1d9669069e6e043f615a4 231 Pfam PF04055 Radical SAM superfamily 35 118 5.9E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_09505 c0bfc93146af8137b38ff3ef0b99e82a 467 SUPERFAMILY SSF51905 37 327 8.51E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09505 c0bfc93146af8137b38ff3ef0b99e82a 467 Gene3D G3DSA:3.30.9.10 133 364 1.9E-60 T 14-10-2018 A4R43_09505 c0bfc93146af8137b38ff3ef0b99e82a 467 Gene3D G3DSA:3.50.50.60 39 398 1.9E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09505 c0bfc93146af8137b38ff3ef0b99e82a 467 Pfam PF01266 FAD dependent oxidoreductase 39 392 2.6E-51 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_33300 ff17fbe8e4b5c67c51015656283619b0 155 Pfam PF12079 Protein of unknown function (DUF3558) 4 150 5.9E-23 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_03865 a520333d99771256ec8597e838ed2ae0 198 Gene3D G3DSA:1.10.10.60 20 67 3.9E-15 T 14-10-2018 A4R43_03865 a520333d99771256ec8597e838ed2ae0 198 SUPERFAMILY SSF46689 22 89 2.64E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03865 a520333d99771256ec8597e838ed2ae0 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 7.4E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03865 a520333d99771256ec8597e838ed2ae0 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 5.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03865 a520333d99771256ec8597e838ed2ae0 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 5.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03865 a520333d99771256ec8597e838ed2ae0 198 Gene3D G3DSA:1.10.357.10 68 186 4.7E-10 T 14-10-2018 A4R43_02875 175160243f388933f55855727204f01d 180 Gene3D G3DSA:1.20.1290.10 13 175 1.8E-32 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_02875 175160243f388933f55855727204f01d 180 Pfam PF02627 Carboxymuconolactone decarboxylase family 41 122 2.7E-8 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_02875 175160243f388933f55855727204f01d 180 SUPERFAMILY SSF69118 1 172 4.84E-38 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_02875 175160243f388933f55855727204f01d 180 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 58 101 3.5E-9 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_26395 bcdb5d2356f9e25ada9dda13346404d5 677 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 4 674 0.0 T 14-10-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 A4R43_26395 bcdb5d2356f9e25ada9dda13346404d5 677 SUPERFAMILY SSF54637 529 675 1.19E-35 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_26395 bcdb5d2356f9e25ada9dda13346404d5 677 Pfam PF00171 Aldehyde dehydrogenase family 12 442 4.7E-62 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_26395 bcdb5d2356f9e25ada9dda13346404d5 677 Gene3D G3DSA:3.40.309.10 259 475 3.2E-149 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_26395 bcdb5d2356f9e25ada9dda13346404d5 677 Pfam PF01575 MaoC like domain 540 650 8.1E-22 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_26395 bcdb5d2356f9e25ada9dda13346404d5 677 Gene3D G3DSA:3.10.129.10 532 677 2.0E-39 T 14-10-2018 A4R43_26395 bcdb5d2356f9e25ada9dda13346404d5 677 Gene3D G3DSA:3.40.605.10 10 487 3.2E-149 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_26395 bcdb5d2356f9e25ada9dda13346404d5 677 SUPERFAMILY SSF53720 4 504 6.54E-81 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2830 3009 5.9E-54 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1336 1512 1.3E-54 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF08990 Erythronolide synthase docking 2 27 2.9E-10 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF52151 2233 2509 1.44E-64 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF53901 31 408 1.17E-100 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.10.129.110 907 1185 2.1E-109 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2085 2199 4.7E-17 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 525 1.7E-16 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF52151 557 838 1.6E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM01294 3114 3181 8.1E-7 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM01294 1617 1684 7.7E-7 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF55048 680 742 3.14E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF51735 2627 2817 1.1E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.30.70.3290 2150 2565 6.1E-162 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF14765 Polyketide synthase dehydratase 918 1183 1.4E-54 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.40.50.720 1186 1583 1.0E-117 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.40.47.10 25 477 6.4E-190 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.40.47.10 1699 2146 3.6E-191 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.30.70.3290 478 898 3.1E-163 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF51735 2827 3070 8.31E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF00698 Acyl transferase domain 559 871 4.7E-95 T 14-10-2018 IPR014043 Acyl transferase A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF00698 Acyl transferase domain 2234 2539 4.0E-90 T 14-10-2018 IPR014043 Acyl transferase A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF08659 KR domain 2830 3008 2.0E-58 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF08659 KR domain 1336 1511 1.5E-53 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF53901 1704 2080 8.16E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3140 3155 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1872 1888 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:1.10.1200.10 1595 1688 4.6E-35 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 295 410 6.2E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1967 2082 7.1E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00825 Beta-ketoacyl synthase 36 463 1.2E-226 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00825 Beta-ketoacyl synthase 1708 2135 3.0E-225 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 287 2.3E-89 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1706 1959 6.3E-94 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.40.366.10 559 855 3.1E-163 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.40.366.10 2234 2522 6.1E-162 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00826 918 1074 2.2E-78 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF51735 1186 1324 9.45E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF51735 1334 1563 3.33E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:1.10.1200.10 3096 3188 6.8E-33 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 561 852 2.8E-114 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2236 2519 3.4E-112 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF47336 1611 1721 9.16E-26 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00823 Phosphopantetheine attachment site 1616 1688 1.7E-32 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SMART SM00823 Phosphopantetheine attachment site 3113 3185 7.6E-32 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF00550 Phosphopantetheine attachment site 1618 1684 1.2E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Pfam PF00550 Phosphopantetheine attachment site 3115 3181 1.3E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 200 216 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 Gene3D G3DSA:3.40.50.720 2577 3082 8.8E-160 T 14-10-2018 A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF47336 3106 3193 3.66E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 SUPERFAMILY SSF55048 2356 2418 4.71E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07915 75d1b258637254428d3baf6ab78755e5 3254 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1643 1658 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 SUPERFAMILY SSF56176 357 445 1.17E-16 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 SMART SM00116 230 278 0.15 T 14-10-2018 IPR000644 CBS domain A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 SMART SM00116 292 340 3.0 T 14-10-2018 IPR000644 CBS domain A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 Gene3D G3DSA:3.10.580.10 202 351 1.4E-37 T 14-10-2018 A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 SUPERFAMILY SSF54631 216 353 3.03E-25 T 14-10-2018 A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 SMART SM01091 355 445 9.2E-14 T 14-10-2018 IPR005170 Transporter-associated domain A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 Pfam PF03471 Transporter associated domain 358 438 2.8E-18 T 14-10-2018 IPR005170 Transporter-associated domain A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 Gene3D G3DSA:3.30.465.10 354 444 4.2E-21 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 Pfam PF01595 Domain of unknown function DUF21 12 205 5.1E-36 T 14-10-2018 IPR002550 CNNM, transmembrane domain A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 Pfam PF00571 CBS domain 226 275 8.7E-5 T 14-10-2018 IPR000644 CBS domain A4R43_06920 66952fa7e3cd733ae02967abc6f6ec40 453 Pfam PF00571 CBS domain 290 340 0.0018 T 14-10-2018 IPR000644 CBS domain A4R43_26870 5c2f058ff02d0ffb224c20865ffcf64c 173 SUPERFAMILY SSF50324 3 157 2.88E-56 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4R43_26870 5c2f058ff02d0ffb224c20865ffcf64c 173 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4R43_26870 5c2f058ff02d0ffb224c20865ffcf64c 173 Pfam PF00719 Inorganic pyrophosphatase 5 156 1.4E-53 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4R43_26870 5c2f058ff02d0ffb224c20865ffcf64c 173 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.55 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4R43_26870 5c2f058ff02d0ffb224c20865ffcf64c 173 Gene3D G3DSA:3.90.80.10 1 161 6.9E-66 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4R43_15315 8d69f45e217c6806d29df7224dae3686 332 Gene3D G3DSA:3.20.20.140 29 319 5.7E-38 T 14-10-2018 A4R43_15315 8d69f45e217c6806d29df7224dae3686 332 Pfam PF04909 Amidohydrolase 12 318 4.2E-45 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_15315 8d69f45e217c6806d29df7224dae3686 332 SUPERFAMILY SSF51556 11 318 9.53E-40 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 PRINTS PR01183 Ribonucleotide reductase large chain signature 436 455 7.9E-46 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 PRINTS PR01183 Ribonucleotide reductase large chain signature 646 668 7.9E-46 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 PRINTS PR01183 Ribonucleotide reductase large chain signature 674 697 7.9E-46 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 PRINTS PR01183 Ribonucleotide reductase large chain signature 571 582 7.9E-46 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 PRINTS PR01183 Ribonucleotide reductase large chain signature 608 631 7.9E-46 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 PRINTS PR01183 Ribonucleotide reductase large chain signature 751 778 7.9E-46 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 SUPERFAMILY SSF48168 143 359 3.27E-60 T 14-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 740 762 - T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 Gene3D G3DSA:3.20.70.20 228 907 7.2E-247 T 14-10-2018 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 288 899 1.3E-214 T 14-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 Pfam PF03477 ATP cone domain 23 119 2.0E-17 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 284 357 1.7E-21 T 14-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 SUPERFAMILY SSF51998 360 901 1.04E-180 T 14-10-2018 A4R43_05185 b57c52c66be318549f42c43cfe3aff3a 1001 Pfam PF02867 Ribonucleotide reductase, barrel domain 361 896 3.0E-182 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_33740 43d8966d46e492939cdd46c8406a7a16 390 Gene3D G3DSA:1.10.10.10 5 68 2.1E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_33740 43d8966d46e492939cdd46c8406a7a16 390 SUPERFAMILY SSF46785 4 68 3.16E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_33740 43d8966d46e492939cdd46c8406a7a16 390 ProSitePatterns PS01125 ROK family signature. 205 232 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_33740 43d8966d46e492939cdd46c8406a7a16 390 Pfam PF00480 ROK family 75 382 2.3E-57 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_33740 43d8966d46e492939cdd46c8406a7a16 390 SUPERFAMILY SSF53067 73 384 2.38E-59 T 14-10-2018 A4R43_33740 43d8966d46e492939cdd46c8406a7a16 390 Gene3D G3DSA:3.30.420.40 195 368 2.1E-88 T 14-10-2018 A4R43_33740 43d8966d46e492939cdd46c8406a7a16 390 Gene3D G3DSA:3.30.420.40 80 378 2.1E-88 T 14-10-2018 A4R43_23620 65e1bb2c0ea284368f01c148fdebe425 258 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 203 220 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A4R43_23620 65e1bb2c0ea284368f01c148fdebe425 258 Pfam PF01255 Putative undecaprenyl diphosphate synthase 35 257 8.0E-71 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4R43_23620 65e1bb2c0ea284368f01c148fdebe425 258 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 28 257 2.4E-64 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4R43_23620 65e1bb2c0ea284368f01c148fdebe425 258 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 27 258 34.972 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4R43_23620 65e1bb2c0ea284368f01c148fdebe425 258 SUPERFAMILY SSF64005 25 252 9.81E-73 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A4R43_23620 65e1bb2c0ea284368f01c148fdebe425 258 Gene3D G3DSA:3.40.1180.10 13 258 4.1E-83 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A4R43_32885 9b663c5fe4c29256dc3a68adcdce01ca 340 Pfam PF01548 Transposase 4 154 5.5E-26 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_32885 9b663c5fe4c29256dc3a68adcdce01ca 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 303 2.7E-14 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_21300 9b663c5fe4c29256dc3a68adcdce01ca 340 Pfam PF01548 Transposase 4 154 5.5E-26 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_21300 9b663c5fe4c29256dc3a68adcdce01ca 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 303 2.7E-14 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_16115 9b663c5fe4c29256dc3a68adcdce01ca 340 Pfam PF01548 Transposase 4 154 5.5E-26 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_16115 9b663c5fe4c29256dc3a68adcdce01ca 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 303 2.7E-14 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_37440 9b663c5fe4c29256dc3a68adcdce01ca 340 Pfam PF01548 Transposase 4 154 5.5E-26 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_37440 9b663c5fe4c29256dc3a68adcdce01ca 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 303 2.7E-14 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_39055 717464da34ac056da291b530eb0607f3 431 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 417 52.016 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4R43_39055 717464da34ac056da291b530eb0607f3 431 SMART SM00382 115 268 4.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_39055 717464da34ac056da291b530eb0607f3 431 Gene3D G3DSA:3.30.50.30 3 50 5.5E-24 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily A4R43_39055 717464da34ac056da291b530eb0607f3 431 Pfam PF07724 AAA domain (Cdc48 subfamily) 116 312 2.7E-50 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_39055 717464da34ac056da291b530eb0607f3 431 SUPERFAMILY SSF52540 59 407 1.18E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39055 717464da34ac056da291b530eb0607f3 431 SUPERFAMILY SSF57716 11 46 1.38E-11 T 14-10-2018 A4R43_39055 717464da34ac056da291b530eb0607f3 431 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4R43_39055 717464da34ac056da291b530eb0607f3 431 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 397 9.7E-16 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_39055 717464da34ac056da291b530eb0607f3 431 SMART SM00994 10 49 1.1E-23 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4R43_39055 717464da34ac056da291b530eb0607f3 431 SMART SM01086 319 413 1.1E-31 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_39055 717464da34ac056da291b530eb0607f3 431 Gene3D G3DSA:3.40.50.300 54 316 1.4E-107 T 14-10-2018 A4R43_39055 717464da34ac056da291b530eb0607f3 431 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 413 2.7E-195 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4R43_39055 717464da34ac056da291b530eb0607f3 431 Gene3D G3DSA:1.10.8.60 318 426 4.8E-39 T 14-10-2018 A4R43_41190 b6179aa028313ad3844ea5dc54886a6d 403 Pfam PF06224 Winged helix DNA-binding domain 37 380 3.0E-73 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 307 3.3E-102 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 SUPERFAMILY SSF52943 3 307 7.19E-83 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 PRINTS PR00126 ATP synthase gamma subunit signature 254 273 8.7E-35 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 PRINTS PR00126 ATP synthase gamma subunit signature 182 199 8.7E-35 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 8.7E-35 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 PRINTS PR00126 ATP synthase gamma subunit signature 285 306 8.7E-35 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 Pfam PF00231 ATP synthase 4 307 5.6E-92 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 293 306 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 307 35.235 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 Gene3D G3DSA:3.40.1380.10 62 226 7.8E-96 T 14-10-2018 A4R43_22355 8f7d86535837e3bf3e3beca42e97a2c9 314 Gene3D G3DSA:1.10.287.80 7 303 7.8E-96 T 14-10-2018 A4R43_16730 3f81579a67b099bfadd0d3d47186120c 143 SMART SM00116 79 126 1.2E-8 T 14-10-2018 IPR000644 CBS domain A4R43_16730 3f81579a67b099bfadd0d3d47186120c 143 SMART SM00116 13 61 1.2E-6 T 14-10-2018 IPR000644 CBS domain A4R43_16730 3f81579a67b099bfadd0d3d47186120c 143 Gene3D G3DSA:3.10.580.10 1 142 6.3E-45 T 14-10-2018 A4R43_16730 3f81579a67b099bfadd0d3d47186120c 143 SUPERFAMILY SSF54631 2 141 1.26E-32 T 14-10-2018 A4R43_16730 3f81579a67b099bfadd0d3d47186120c 143 Pfam PF00571 CBS domain 72 124 4.7E-10 T 14-10-2018 IPR000644 CBS domain A4R43_16730 3f81579a67b099bfadd0d3d47186120c 143 Pfam PF00571 CBS domain 14 61 9.4E-10 T 14-10-2018 IPR000644 CBS domain A4R43_36520 e12cfd58b139c83747b408dc51a876d4 330 SUPERFAMILY SSF56091 11 202 4.32E-36 T 14-10-2018 A4R43_36520 e12cfd58b139c83747b408dc51a876d4 330 SUPERFAMILY SSF50249 208 325 1.37E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_36520 e12cfd58b139c83747b408dc51a876d4 330 Pfam PF01068 ATP dependent DNA ligase domain 30 202 8.3E-26 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A4R43_36520 e12cfd58b139c83747b408dc51a876d4 330 Gene3D G3DSA:3.30.470.30 38 152 3.0E-45 T 14-10-2018 A4R43_36520 e12cfd58b139c83747b408dc51a876d4 330 Gene3D G3DSA:3.30.1490.70 26 202 3.0E-45 T 14-10-2018 A4R43_36520 e12cfd58b139c83747b408dc51a876d4 330 Pfam PF04679 ATP dependent DNA ligase C terminal region 223 319 1.6E-25 T 14-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A4R43_36520 e12cfd58b139c83747b408dc51a876d4 330 Gene3D G3DSA:2.40.50.140 206 326 1.4E-39 T 14-10-2018 A4R43_36520 e12cfd58b139c83747b408dc51a876d4 330 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 21 324 6.8E-76 T 14-10-2018 IPR014146 DNA ligase D, ligase domain A4R43_32150 ee819a66327e12d944158db8724b59a0 388 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 121 166 1.7E-5 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 A4R43_32150 ee819a66327e12d944158db8724b59a0 388 Gene3D G3DSA:3.40.50.1820 21 376 5.5E-76 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_32150 ee819a66327e12d944158db8724b59a0 388 SUPERFAMILY SSF53474 115 374 2.05E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_30860 5a2e5affc2c7f143fca7e2fa9f5c0fdf 696 SUPERFAMILY SSF63829 343 642 1.05E-7 T 14-10-2018 A4R43_30860 5a2e5affc2c7f143fca7e2fa9f5c0fdf 696 Pfam PF05787 Bacterial protein of unknown function (DUF839) 103 653 9.8E-159 T 14-10-2018 IPR008557 Protein of unknown function DUF839 A4R43_02990 f2c7b80b011d36102ec8b9b0bc716d5e 278 SUPERFAMILY SSF49482 25 262 1.57E-75 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4R43_02990 f2c7b80b011d36102ec8b9b0bc716d5e 278 Pfam PF00775 Dioxygenase 100 271 8.4E-58 T 14-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 A4R43_02990 f2c7b80b011d36102ec8b9b0bc716d5e 278 TIGRFAM TIGR02438 catachol_actin: catechol 1,2-dioxygenase 2 275 2.9E-144 T 14-10-2018 IPR012800 Catechol 1,2-dioxygenase, actinobacteria KEGG: 00361+1.13.11.1|KEGG: 00362+1.13.11.1|KEGG: 00364+1.13.11.1|KEGG: 00623+1.13.11.1 A4R43_02990 f2c7b80b011d36102ec8b9b0bc716d5e 278 Pfam PF04444 Catechol dioxygenase N terminus 30 96 1.7E-17 T 14-10-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 A4R43_02990 f2c7b80b011d36102ec8b9b0bc716d5e 278 Gene3D G3DSA:1.10.8.580 24 93 5.9E-32 T 14-10-2018 A4R43_02990 f2c7b80b011d36102ec8b9b0bc716d5e 278 Gene3D G3DSA:2.60.130.10 94 276 6.6E-65 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4R43_33060 5c143e0ce6f747174b7121daff87912b 373 Pfam PF13439 Glycosyltransferase Family 4 15 179 6.9E-25 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_33060 5c143e0ce6f747174b7121daff87912b 373 Pfam PF00534 Glycosyl transferases group 1 193 344 9.8E-22 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_33060 5c143e0ce6f747174b7121daff87912b 373 Gene3D G3DSA:3.40.50.2000 2 189 1.3E-32 T 14-10-2018 A4R43_33060 5c143e0ce6f747174b7121daff87912b 373 SUPERFAMILY SSF53756 3 364 9.71E-70 T 14-10-2018 A4R43_33060 5c143e0ce6f747174b7121daff87912b 373 Gene3D G3DSA:3.40.50.2000 190 346 7.4E-28 T 14-10-2018 A4R43_11320 96572813a61abb46d85e711255bbce0b 417 SUPERFAMILY SSF90002 252 365 5.75E-9 T 14-10-2018 A4R43_11320 96572813a61abb46d85e711255bbce0b 417 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 252 365 1.9E-17 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4R43_11320 96572813a61abb46d85e711255bbce0b 417 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 60 182 5.6E-12 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4R43_11320 96572813a61abb46d85e711255bbce0b 417 Gene3D G3DSA:3.40.50.300 5 221 7.4E-14 T 14-10-2018 A4R43_11320 96572813a61abb46d85e711255bbce0b 417 SMART SM00833 249 365 2.2E-31 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 Gene3D G3DSA:3.60.20.10 22 453 8.7E-169 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 Gene3D G3DSA:2.160.20.60 1244 1511 2.5E-104 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 SUPERFAMILY SSF69336 1240 1500 2.22E-90 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 Gene3D G3DSA:3.20.20.70 811 1241 3.6E-189 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 SUPERFAMILY SSF56235 22 449 4.72E-140 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 Gene3D G3DSA:3.20.20.70 454 810 3.8E-130 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 Pfam PF01645 Conserved region in glutamate synthase 826 1190 2.6E-152 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 SUPERFAMILY SSF51395 462 1225 8.14E-258 T 14-10-2018 A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 Pfam PF04898 Glutamate synthase central domain 474 760 2.8E-108 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 Pfam PF00310 Glutamine amidotransferases class-II 22 447 6.6E-169 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4R43_17155 85616f39df13ecd64f2873c3688e08a2 1522 Pfam PF01493 GXGXG motif 1271 1448 1.9E-77 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 A4R43_22860 f62d18424846886ad7916075af0e0904 399 Gene3D G3DSA:1.10.357.10 258 398 2.6E-24 T 14-10-2018 A4R43_22860 f62d18424846886ad7916075af0e0904 399 Gene3D G3DSA:1.10.357.10 56 197 1.9E-22 T 14-10-2018 A4R43_22860 f62d18424846886ad7916075af0e0904 399 Gene3D G3DSA:1.10.10.60 12 54 8.8E-19 T 14-10-2018 A4R43_22860 f62d18424846886ad7916075af0e0904 399 Gene3D G3DSA:1.10.10.60 216 257 8.0E-23 T 14-10-2018 A4R43_22860 f62d18424846886ad7916075af0e0904 399 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 62 3.7E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22860 f62d18424846886ad7916075af0e0904 399 Pfam PF00440 Bacterial regulatory proteins, tetR family 221 267 7.3E-19 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22860 f62d18424846886ad7916075af0e0904 399 SUPERFAMILY SSF46689 212 290 4.99E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22860 f62d18424846886ad7916075af0e0904 399 SUPERFAMILY SSF46689 7 81 3.5E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22860 f62d18424846886ad7916075af0e0904 399 ProSitePatterns PS01081 TetR-type HTH domain signature. 233 264 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_22860 f62d18424846886ad7916075af0e0904 399 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 242 265 7.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22860 f62d18424846886ad7916075af0e0904 399 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 221 234 7.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_18435 f2366e4c1be6ad4adff6ace4ec8b7b60 289 SUPERFAMILY SSF53098 44 233 1.82E-56 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_18435 f2366e4c1be6ad4adff6ace4ec8b7b60 289 Hamap MF_00052_B Ribonuclease HII [rnhB]. 51 232 34.046 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 A4R43_18435 f2366e4c1be6ad4adff6ace4ec8b7b60 289 Gene3D G3DSA:3.30.420.10 34 255 2.6E-63 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_18435 f2366e4c1be6ad4adff6ace4ec8b7b60 289 Pfam PF01351 Ribonuclease HII 53 232 7.5E-35 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain A4R43_26680 41ef0a63a89820b7227b7cac49057aed 366 SUPERFAMILY SSF53822 83 346 2.72E-40 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_26680 41ef0a63a89820b7227b7cac49057aed 366 Pfam PF13377 Periplasmic binding protein-like domain 178 353 5.6E-27 T 14-10-2018 A4R43_26680 41ef0a63a89820b7227b7cac49057aed 366 Gene3D G3DSA:3.40.50.2300 170 315 2.3E-51 T 14-10-2018 A4R43_26680 41ef0a63a89820b7227b7cac49057aed 366 SMART SM00354 10 81 2.1E-11 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_26680 41ef0a63a89820b7227b7cac49057aed 366 Gene3D G3DSA:3.40.50.2300 65 331 2.3E-51 T 14-10-2018 A4R43_26680 41ef0a63a89820b7227b7cac49057aed 366 Gene3D G3DSA:1.10.260.40 4 64 1.3E-16 T 14-10-2018 A4R43_26680 41ef0a63a89820b7227b7cac49057aed 366 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 54 4.5E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_26680 41ef0a63a89820b7227b7cac49057aed 366 SUPERFAMILY SSF47413 10 68 2.95E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_06155 4e2b47bcc3f87f5f6f90a322fec12f5d 403 Pfam PF00990 Diguanylate cyclase, GGDEF domain 234 395 4.0E-41 T 14-10-2018 IPR000160 GGDEF domain A4R43_06155 4e2b47bcc3f87f5f6f90a322fec12f5d 403 Gene3D G3DSA:3.30.70.270 228 400 8.2E-54 T 14-10-2018 A4R43_06155 4e2b47bcc3f87f5f6f90a322fec12f5d 403 SMART SM00267 223 400 2.7E-53 T 14-10-2018 IPR000160 GGDEF domain A4R43_06155 4e2b47bcc3f87f5f6f90a322fec12f5d 403 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 230 397 1.3E-49 T 14-10-2018 IPR000160 GGDEF domain A4R43_06155 4e2b47bcc3f87f5f6f90a322fec12f5d 403 SUPERFAMILY SSF55073 240 398 2.2E-43 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_03485 5ce1cc727bdf39e87ca6d1a1b8f421d4 271 Pfam PF12833 Helix-turn-helix domain 173 248 2.1E-14 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03485 5ce1cc727bdf39e87ca6d1a1b8f421d4 271 Gene3D G3DSA:1.10.10.60 150 256 1.3E-17 T 14-10-2018 A4R43_03485 5ce1cc727bdf39e87ca6d1a1b8f421d4 271 SMART SM00342 164 248 8.2E-8 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03485 5ce1cc727bdf39e87ca6d1a1b8f421d4 271 SUPERFAMILY SSF46689 211 248 4.93E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_26010 9dc000f57558ce06798fbff8e39b2e80 1029 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 560 667 1.8E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_26010 9dc000f57558ce06798fbff8e39b2e80 1029 Pfam PF08376 Nitrate and nitrite sensing 92 330 2.4E-39 T 14-10-2018 IPR013587 Nitrate/nitrite sensing protein A4R43_26010 9dc000f57558ce06798fbff8e39b2e80 1029 SUPERFAMILY SSF55874 545 667 5.63E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_26010 9dc000f57558ce06798fbff8e39b2e80 1029 SMART SM00387 557 668 1.0E-4 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_26010 9dc000f57558ce06798fbff8e39b2e80 1029 Gene3D G3DSA:3.30.565.10 529 668 1.5E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF14765 Polyketide synthase dehydratase 5691 5960 5.5E-59 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF14765 Polyketide synthase dehydratase 2491 2761 1.8E-56 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF14765 Polyketide synthase dehydratase 8982 9248 8.5E-56 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF14765 Polyketide synthase dehydratase 4082 4349 9.1E-54 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF14765 Polyketide synthase dehydratase 872 1141 9.4E-56 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF14765 Polyketide synthase dehydratase 7333 7595 1.1E-50 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.30.70.3290 468 852 3.9E-137 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4508 4673 3.2E-49 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1300 1465 7.9E-51 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9439 9619 2.4E-46 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7766 7940 1.6E-52 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2898 3063 3.6E-55 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6126 6302 1.1E-59 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 7601 7753 1.34E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 9439 9676 2.77E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.366.10 8635 8917 2.5E-140 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.366.10 534 808 3.9E-137 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.366.10 6997 7269 3.8E-131 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.366.10 3751 4017 9.8E-123 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.366.10 2161 2427 3.7E-119 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.366.10 5361 5627 4.1E-123 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.47.10 3241 3693 2.8E-190 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.47.10 6480 6933 1.0E-191 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.47.10 4852 5302 1.5E-193 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.47.10 1652 2098 4.5E-186 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.47.10 8118 8565 6.2E-187 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.47.10 28 467 1.4E-177 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF52151 6997 7265 2.3E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF55048 2280 2334 4.05E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.30.70.3290 8567 8961 2.5E-140 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6489 6737 2.1E-91 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4861 5110 2.6E-93 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3250 3498 6.8E-90 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1660 1908 7.6E-90 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 275 4.6E-82 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8127 8375 2.7E-90 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.50.720 9253 9685 3.5E-122 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF52151 5361 5612 1.2E-62 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00825 Beta-ketoacyl synthase 6491 6913 6.2E-222 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00825 Beta-ketoacyl synthase 1662 2084 3.3E-212 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00825 Beta-ketoacyl synthase 3252 3674 3.9E-221 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00825 Beta-ketoacyl synthase 8129 8551 2.8E-217 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00825 Beta-ketoacyl synthase 4863 5286 1.6E-224 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00825 Beta-ketoacyl synthase 37 451 1.5E-204 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM01294 3161 3228 1.8E-5 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM01294 4771 4838 4.9E-7 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM01294 8038 8105 1.4E-5 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM01294 6400 6467 1.4E-5 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM01294 1567 1634 1.1E-5 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM01294 9711 9778 4.5E-7 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 5967 6116 5.12E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.10.129.110 8971 9252 2.2E-113 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.10.129.110 5680 5964 1.5E-113 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.10.129.110 861 1145 1.9E-109 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.10.129.110 2480 2763 6.7E-112 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.10.129.110 7322 7601 4.6E-109 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.10.129.110 4071 4348 4.5E-113 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF47336 9703 9789 1.44E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 8288 8304 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF55048 8754 8815 1.44E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4797 4812 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 1147 1289 2.24E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF55048 653 707 5.89E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF52151 8634 8909 4.45E-69 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 188 204 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5023 5039 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3411 3427 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF08659 KR domain 7768 7938 3.9E-57 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF08659 KR domain 9439 9611 1.1E-53 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF08659 KR domain 2898 3062 2.4E-55 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF08659 KR domain 6126 6300 5.7E-58 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF08659 KR domain 4510 4672 1.1E-52 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF08659 KR domain 1300 1463 1.5E-52 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.30.70.3290 6934 7313 3.8E-131 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 9252 9428 2.87E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF52151 3751 4002 9.68E-64 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 4505 4732 1.35E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:1.10.1200.10 8016 8109 1.2E-33 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:1.10.1200.10 6378 6471 3.6E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:1.10.1200.10 1548 1640 2.4E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:1.10.1200.10 9693 9785 4.9E-35 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:1.10.1200.10 3143 3235 3.3E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:1.10.1200.10 4753 4845 2.4E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF55048 3870 3924 2.88E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF53901 32 394 2.89E-98 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF53901 1657 2029 9.62E-103 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6650 6666 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF47336 6393 6504 7.46E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.30.70.3290 5303 5671 4.1E-123 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00823 Phosphopantetheine attachment site 9710 9782 2.0E-33 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00823 Phosphopantetheine attachment site 3160 3232 8.7E-32 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00823 Phosphopantetheine attachment site 6399 6471 3.9E-30 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00823 Phosphopantetheine attachment site 1566 1638 2.3E-32 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00823 Phosphopantetheine attachment site 8037 8109 4.2E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00823 Phosphopantetheine attachment site 4770 4842 2.1E-34 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8637 8913 4.7E-111 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 536 805 6.2E-108 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3753 4014 2.1E-101 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5363 5624 2.1E-100 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2163 2424 2.9E-98 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6999 7266 1.8E-103 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF47336 8032 8142 2.88E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1821 1837 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.50.720 5965 6362 1.3E-129 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.50.720 7602 8004 1.2E-124 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.50.720 2764 3130 2.2E-115 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.50.720 1146 1533 8.9E-110 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF53901 3246 3620 4.53E-103 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF47336 3154 3265 1.57E-25 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.30.70.3290 3694 4061 9.8E-123 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00012 Phosphopantetheine attachment site. 9737 9752 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8064 8079 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 4356 4497 1.06E-19 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 2895 3126 2.14E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1916 2031 1.1E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3506 3621 2.1E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5118 5233 2.8E-45 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 283 398 1.6E-41 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6745 6860 5.1E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 8383 8498 8.4E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF53901 8123 8498 4.26E-105 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF53901 6485 6857 2.06E-106 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 6124 6341 7.09E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF55048 5480 5534 3.4E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00550 Phosphopantetheine attachment site 9713 9778 3.5E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00550 Phosphopantetheine attachment site 8039 8105 2.1E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00550 Phosphopantetheine attachment site 6401 6467 9.8E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00550 Phosphopantetheine attachment site 3163 3228 2.3E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00550 Phosphopantetheine attachment site 1568 1634 1.8E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00550 Phosphopantetheine attachment site 4772 4838 3.4E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6426 6441 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00826 2491 2652 6.9E-82 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00826 872 1031 1.6E-81 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00826 4082 4243 3.3E-85 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00826 7333 7495 3.1E-89 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00826 5691 5853 1.0E-85 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SMART SM00826 8982 9144 6.6E-91 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 7764 8004 1.09E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF47336 1560 1675 6.28E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5236 5325 2.9E-13 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6863 6974 1.0E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2034 2121 2.7E-9 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 401 516 2.5E-14 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 8501 8597 2.9E-12 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3624 3715 1.4E-13 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF52151 2161 2412 1.44E-61 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 2708 2886 6.03E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF55048 7116 7170 3.4E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF51735 1296 1524 2.26E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.30.70.3290 2100 2471 3.7E-119 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF53901 4857 5231 3.03E-105 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF52151 533 798 2.62E-71 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.50.11460 4349 4496 5.0E-31 T 14-10-2018 A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00698 Acyl transferase domain 8637 8933 2.8E-53 T 14-10-2018 IPR014043 Acyl transferase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00698 Acyl transferase domain 2163 2443 3.9E-43 T 14-10-2018 IPR014043 Acyl transferase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00698 Acyl transferase domain 3753 4028 1.7E-43 T 14-10-2018 IPR014043 Acyl transferase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00698 Acyl transferase domain 5363 5606 4.4E-43 T 14-10-2018 IPR014043 Acyl transferase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00698 Acyl transferase domain 6999 7285 6.8E-47 T 14-10-2018 IPR014043 Acyl transferase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Pfam PF00698 Acyl transferase domain 535 823 1.1E-50 T 14-10-2018 IPR014043 Acyl transferase A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 SUPERFAMILY SSF47336 4764 4876 2.75E-25 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3187 3202 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38510 4d8f4f00e09ce9fcfb54fd3ac4d8151e 9864 Gene3D G3DSA:3.40.50.720 4501 4738 3.6E-68 T 14-10-2018 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 Pfam PF08245 Mur ligase middle domain 117 299 2.6E-26 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 Pfam PF02875 Mur ligase family, glutamate ligase domain 320 405 8.3E-23 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 Pfam PF01225 Mur ligase family, catalytic domain 12 113 2.8E-26 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 8 467 38.538 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 SUPERFAMILY SSF53244 319 463 5.04E-44 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 SUPERFAMILY SSF53623 98 318 1.05E-56 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 Gene3D G3DSA:3.40.1190.10 101 317 3.9E-67 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 Gene3D G3DSA:3.90.190.20 318 471 5.5E-54 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 SUPERFAMILY SSF51984 9 100 1.1E-23 T 14-10-2018 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 Gene3D G3DSA:3.40.50.720 9 100 4.6E-30 T 14-10-2018 A4R43_16560 a8a713c9ddd0d9a7dfbecd8aca6ed916 472 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 11 461 2.8E-148 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Gene3D G3DSA:1.10.601.10 208 313 6.9E-51 T 14-10-2018 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Gene3D G3DSA:1.10.601.10 170 207 3.0E-9 T 14-10-2018 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 SUPERFAMILY SSF88659 373 473 2.62E-26 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 237 473 4.3E-113 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Pfam PF04539 Sigma-70 region 3 320 395 1.5E-28 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 265 278 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 40 474 32.459 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 434 460 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 PRINTS PR00046 Major sigma-70 factor signature 289 297 2.9E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 PRINTS PR00046 Major sigma-70 factor signature 449 460 2.9E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 PRINTS PR00046 Major sigma-70 factor signature 434 449 2.9E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 PRINTS PR00046 Major sigma-70 factor signature 265 278 2.9E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 PRINTS PR00046 Major sigma-70 factor signature 413 425 2.9E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Pfam PF00140 Sigma-70 factor, region 1.2 172 205 4.1E-16 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Gene3D G3DSA:1.10.10.10 314 389 2.6E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 240 462 2.0E-34 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Pfam PF04545 Sigma-70, region 4 409 462 1.4E-18 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Gene3D G3DSA:1.10.10.10 397 474 2.7E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 Pfam PF04542 Sigma-70 region 2 241 310 1.6E-22 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 SUPERFAMILY SSF88946 169 311 2.49E-53 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_14085 23fac2d3b270d95c94f2ed303863b59c 474 SUPERFAMILY SSF88659 314 387 1.31E-22 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 6.1E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 SMART SM00895 92 215 1.6E-18 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.8E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.8E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 SUPERFAMILY SSF46785 6 76 4.77E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 Pfam PF07729 FCD domain 93 214 3.5E-20 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 Gene3D G3DSA:1.10.10.10 8 76 1.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 SMART SM00345 13 72 2.8E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 SUPERFAMILY SSF48008 90 218 3.14E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_12720 c36e0c2137fb0b4a149d7d31793ad135 221 Gene3D G3DSA:1.20.120.530 77 220 7.2E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_07345 aa9458c02c3deed56a1eb7b587120f4c 249 SUPERFAMILY SSF49899 31 247 8.31E-59 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_07345 aa9458c02c3deed56a1eb7b587120f4c 249 Gene3D G3DSA:2.60.120.200 27 248 4.1E-84 T 14-10-2018 A4R43_07345 aa9458c02c3deed56a1eb7b587120f4c 249 Pfam PF08787 Alginate lyase 37 247 5.2E-40 T 14-10-2018 IPR014895 Alginate lyase 2 A4R43_38155 a7a76fbc6ac900e5bae98d9df5bed94a 432 SUPERFAMILY SSF54826 3 136 3.03E-35 T 14-10-2018 A4R43_38155 a7a76fbc6ac900e5bae98d9df5bed94a 432 SUPERFAMILY SSF51604 182 426 3.67E-64 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_38155 a7a76fbc6ac900e5bae98d9df5bed94a 432 Gene3D G3DSA:3.30.390.10 1 129 1.5E-48 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_38155 a7a76fbc6ac900e5bae98d9df5bed94a 432 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 243 274 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4R43_38155 a7a76fbc6ac900e5bae98d9df5bed94a 432 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 35 134 2.4E-5 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_38155 a7a76fbc6ac900e5bae98d9df5bed94a 432 Pfam PF13378 Enolase C-terminal domain-like 200 414 3.3E-58 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_38155 a7a76fbc6ac900e5bae98d9df5bed94a 432 Gene3D G3DSA:3.20.20.120 130 431 2.2E-103 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_38155 a7a76fbc6ac900e5bae98d9df5bed94a 432 SMART SM00922 197 293 2.9E-25 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_25180 c8735a09fb5d1a5513cbf0119107463e 218 Gene3D G3DSA:3.40.50.2300 1 121 6.6E-30 T 14-10-2018 A4R43_25180 c8735a09fb5d1a5513cbf0119107463e 218 SMART SM00862 145 217 6.3E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25180 c8735a09fb5d1a5513cbf0119107463e 218 Gene3D G3DSA:1.10.10.10 122 218 1.4E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25180 c8735a09fb5d1a5513cbf0119107463e 218 Pfam PF00072 Response regulator receiver domain 3 112 2.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25180 c8735a09fb5d1a5513cbf0119107463e 218 SUPERFAMILY SSF52172 1 169 4.7E-34 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_25180 c8735a09fb5d1a5513cbf0119107463e 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 8.0E-17 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25180 c8735a09fb5d1a5513cbf0119107463e 218 SMART SM00448 1 112 1.9E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Pfam PF00698 Acyl transferase domain 1137 1415 6.1E-33 T 14-10-2018 IPR014043 Acyl transferase A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SMART SM00825 Beta-ketoacyl synthase 618 1050 2.4E-108 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Pfam PF03060 Nitronate monooxygenase 45 183 4.4E-10 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Pfam PF03060 Nitronate monooxygenase 260 476 4.6E-9 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SUPERFAMILY SSF47336 1577 1673 1.15E-11 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1866 2088 3.7E-26 T 14-10-2018 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SUPERFAMILY SSF53901 614 1045 2.72E-76 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Gene3D G3DSA:3.30.70.250 1260 1327 1.1E-73 T 14-10-2018 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 617 874 6.2E-65 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Gene3D G3DSA:3.20.20.70 257 608 5.6E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Gene3D G3DSA:3.20.20.70 13 256 7.2E-37 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 882 999 1.3E-37 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Gene3D G3DSA:3.40.47.10 613 1115 1.4E-155 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Pfam PF08659 KR domain 1867 2086 5.3E-34 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SUPERFAMILY SSF51412 22 200 1.92E-19 T 14-10-2018 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SUPERFAMILY SSF52151 1135 1429 3.14E-50 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SUPERFAMILY SSF55048 1264 1326 1.96E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1138 1436 3.1E-28 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Gene3D G3DSA:3.40.366.10 1138 1416 1.1E-73 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SUPERFAMILY SSF51412 259 516 2.23E-17 T 14-10-2018 A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 Gene3D G3DSA:1.10.1200.10 1565 1662 4.3E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_14755 db73958cc88aee4f63a95581d2fc3dca 2141 SUPERFAMILY SSF51735 1864 2132 2.5E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_06285 03990453f80b9cfe6d093d2c22976686 332 SUPERFAMILY SSF56176 1 218 2.06E-57 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_06285 03990453f80b9cfe6d093d2c22976686 332 SUPERFAMILY SSF55447 225 330 1.02E-26 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily A4R43_06285 03990453f80b9cfe6d093d2c22976686 332 Gene3D G3DSA:3.30.465.10 1 220 3.3E-80 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_06285 03990453f80b9cfe6d093d2c22976686 332 Gene3D G3DSA:3.30.390.50 222 329 1.2E-23 T 14-10-2018 A4R43_06285 03990453f80b9cfe6d093d2c22976686 332 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 218 4.1E-46 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4R43_06285 03990453f80b9cfe6d093d2c22976686 332 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 225 322 2.4E-18 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_06285 03990453f80b9cfe6d093d2c22976686 332 SMART SM01092 225 327 8.8E-29 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 SMART SM00448 3 116 4.3E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 SUPERFAMILY SSF46894 144 214 5.1E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 SMART SM00421 151 208 4.0E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 8.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 8.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 8.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 SUPERFAMILY SSF52172 3 134 2.56E-31 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 Gene3D G3DSA:3.40.50.12740 4 214 2.9E-67 T 14-10-2018 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 6.2E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11645 d120a7b9579125d69a89770a65c583aa 232 Pfam PF00072 Response regulator receiver domain 5 115 2.0E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 401 1.2E-122 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 PIRSF PIRSF000124 1 411 1.3E-56 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 Gene3D G3DSA:3.40.50.720 192 410 3.6E-63 T 14-10-2018 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 312 401 1.4E-17 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 173 8.7E-31 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 193 284 7.2E-31 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 SUPERFAMILY SSF48179 193 290 1.29E-31 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 Gene3D G3DSA:3.40.50.720 1 189 3.9E-52 T 14-10-2018 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 SUPERFAMILY SSF52413 297 404 2.88E-21 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 PIRSF PIRSF500136 1 411 7.6E-140 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 SUPERFAMILY SSF51735 1 187 1.5E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40830 6f7799bd54b8481e24f0e2e6af61a12a 412 SMART SM00984 311 406 1.7E-21 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 Gene3D G3DSA:3.20.20.80 1 455 3.3E-158 T 14-10-2018 A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 377 388 4.0E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 286 300 4.0E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 357 365 4.0E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 398 415 4.0E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 422 434 4.0E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 TIGRFAM TIGR03356 BGL: beta-galactosidase 6 444 2.0E-172 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 357 365 - T 14-10-2018 IPR018120 Glycoside hydrolase family 1, active site A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 SUPERFAMILY SSF51445 5 454 2.49E-148 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_06495 23e852872a645db00a717fc88f7fa1c3 455 Pfam PF00232 Glycosyl hydrolase family 1 5 452 2.0E-145 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_31675 36bf49620c817b90d859bffd34911d76 328 Pfam PF16868 NMT1-like family 47 324 1.6E-70 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A4R43_31675 36bf49620c817b90d859bffd34911d76 328 SUPERFAMILY SSF53850 44 325 4.35E-61 T 14-10-2018 A4R43_31675 36bf49620c817b90d859bffd34911d76 328 Gene3D G3DSA:3.40.190.10 129 267 6.7E-84 T 14-10-2018 A4R43_31675 36bf49620c817b90d859bffd34911d76 328 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 324 6.7E-86 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A4R43_31675 36bf49620c817b90d859bffd34911d76 328 Gene3D G3DSA:3.40.190.10 47 324 6.7E-84 T 14-10-2018 A4R43_20730 461b44e320babfd505201c74e077ab42 982 SUPERFAMILY SSF48452 92 258 8.86E-40 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 Gene3D G3DSA:1.25.40.10 759 981 9.6E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 PRINTS PR00364 Disease resistance protein signature 367 381 5.8E-11 T 14-10-2018 A4R43_20730 461b44e320babfd505201c74e077ab42 982 PRINTS PR00364 Disease resistance protein signature 452 466 5.8E-11 T 14-10-2018 A4R43_20730 461b44e320babfd505201c74e077ab42 982 PRINTS PR00364 Disease resistance protein signature 290 305 5.8E-11 T 14-10-2018 A4R43_20730 461b44e320babfd505201c74e077ab42 982 SUPERFAMILY SSF52540 257 520 1.08E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20730 461b44e320babfd505201c74e077ab42 982 SMART SM00028 100 133 17.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 SMART SM00028 869 902 96.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 SMART SM00028 830 863 100.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 SMART SM00028 790 823 280.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 Gene3D G3DSA:1.25.40.10 662 758 6.8E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 Gene3D G3DSA:1.25.40.10 92 254 4.5E-50 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 Gene3D G3DSA:1.10.10.10 1 90 1.2E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20730 461b44e320babfd505201c74e077ab42 982 Pfam PF03704 Bacterial transcriptional activator domain 95 240 6.4E-45 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_20730 461b44e320babfd505201c74e077ab42 982 Gene3D G3DSA:3.40.50.300 255 407 1.6E-25 T 14-10-2018 A4R43_20730 461b44e320babfd505201c74e077ab42 982 SMART SM01043 95 240 1.1E-51 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_20730 461b44e320babfd505201c74e077ab42 982 SUPERFAMILY SSF48452 691 908 1.33E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20730 461b44e320babfd505201c74e077ab42 982 SMART SM00862 15 88 2.1E-15 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_20730 461b44e320babfd505201c74e077ab42 982 Pfam PF00931 NB-ARC domain 288 522 1.1E-12 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_20730 461b44e320babfd505201c74e077ab42 982 SUPERFAMILY SSF46894 3 88 4.25E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_20730 461b44e320babfd505201c74e077ab42 982 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 88 2.2E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1261 1335 1.2E-22 T 14-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 SUPERFAMILY SSF69322 586 822 1.83E-7 T 14-10-2018 A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 SUPERFAMILY SSF140453 88 163 1.44E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Gene3D G3DSA:2.180.10.10 1059 1335 6.5E-35 T 14-10-2018 A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Gene3D G3DSA:3.90.930.1 812 980 1.5E-6 T 14-10-2018 A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Gene3D G3DSA:3.90.930.1 573 708 7.1E-14 T 14-10-2018 A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 951 977 5.8E-5 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 828 869 1.3E-8 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 660 700 9.3E-11 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 684 722 1.5E-8 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 870 904 3.3E-5 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 768 806 1.2E-6 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1146 1177 6.5E-9 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 585 617 2.2E-4 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1066 1094 0.0032 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 725 763 5.2E-8 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 618 654 9.5E-9 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 514 550 2.9E-7 T 14-10-2018 IPR006530 YD repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Pfam PF03527 RHS protein 1236 1265 4.8E-9 T 14-10-2018 IPR001826 RHS protein A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Pfam PF05593 RHS Repeat 660 696 1.6E-9 T 14-10-2018 IPR031325 RHS repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Pfam PF05593 RHS Repeat 828 864 6.6E-7 T 14-10-2018 IPR031325 RHS repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Pfam PF05593 RHS Repeat 858 886 1.3E-4 T 14-10-2018 IPR031325 RHS repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Pfam PF05593 RHS Repeat 725 759 2.1E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Pfam PF05593 RHS Repeat 1146 1175 1.2E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Pfam PF05593 RHS Repeat 618 654 1.5E-9 T 14-10-2018 IPR031325 RHS repeat A4R43_03985 b6f7206c9586fa545f85e8479aa21ad3 1480 Pfam PF05593 RHS Repeat 579 612 1.9E-7 T 14-10-2018 IPR031325 RHS repeat A4R43_21425 fb3a4a1be648a524396321b74d763e24 141 Gene3D G3DSA:3.40.630.30 1 135 2.4E-22 T 14-10-2018 A4R43_21425 fb3a4a1be648a524396321b74d763e24 141 SUPERFAMILY SSF55729 1 138 1.89E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_21425 fb3a4a1be648a524396321b74d763e24 141 Pfam PF00583 Acetyltransferase (GNAT) family 49 128 1.5E-10 T 14-10-2018 IPR000182 GNAT domain A4R43_04580 6bdd3e48d54a1702836980c0158669d4 261 SUPERFAMILY SSF53474 8 250 8.03E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_04580 6bdd3e48d54a1702836980c0158669d4 261 Pfam PF00975 Thioesterase domain 22 248 3.3E-31 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_04580 6bdd3e48d54a1702836980c0158669d4 261 Gene3D G3DSA:3.40.50.1820 9 247 3.0E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00310 289ee4e89d0dc45e0891fa680e35d450 527 Gene3D G3DSA:3.40.50.12780 5 416 1.8E-99 T 14-10-2018 A4R43_00310 289ee4e89d0dc45e0891fa680e35d450 527 Pfam PF00501 AMP-binding enzyme 20 420 8.3E-85 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_00310 289ee4e89d0dc45e0891fa680e35d450 527 SUPERFAMILY SSF56801 7 517 1.14E-132 T 14-10-2018 A4R43_00310 289ee4e89d0dc45e0891fa680e35d450 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 496 8.3E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_00310 289ee4e89d0dc45e0891fa680e35d450 527 Gene3D G3DSA:3.30.300.310 417 521 3.3E-27 T 14-10-2018 A4R43_31145 4b3a9bddd5d036e5c1d0216f0c09358f 342 SUPERFAMILY SSF52518 19 197 1.39E-65 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_31145 4b3a9bddd5d036e5c1d0216f0c09358f 342 Gene3D G3DSA:3.40.50.970 15 209 1.8E-77 T 14-10-2018 A4R43_31145 4b3a9bddd5d036e5c1d0216f0c09358f 342 Gene3D G3DSA:3.40.50.920 210 340 8.9E-41 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_31145 4b3a9bddd5d036e5c1d0216f0c09358f 342 Pfam PF02779 Transketolase, pyrimidine binding domain 19 193 9.5E-45 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_31145 4b3a9bddd5d036e5c1d0216f0c09358f 342 Pfam PF02780 Transketolase, C-terminal domain 214 332 8.4E-33 T 14-10-2018 IPR033248 Transketolase, C-terminal domain A4R43_31145 4b3a9bddd5d036e5c1d0216f0c09358f 342 SMART SM00861 19 194 6.3E-67 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_31145 4b3a9bddd5d036e5c1d0216f0c09358f 342 SUPERFAMILY SSF52922 213 339 4.19E-32 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_40810 19a7cfd8f9101361ef2a763fdf9458cf 349 Gene3D G3DSA:3.30.1370.60 78 319 1.7E-91 T 14-10-2018 A4R43_40810 19a7cfd8f9101361ef2a763fdf9458cf 349 SUPERFAMILY SSF89733 11 345 8.76E-83 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 A4R43_40810 19a7cfd8f9101361ef2a763fdf9458cf 349 Gene3D G3DSA:1.10.1530.10 26 345 1.7E-91 T 14-10-2018 A4R43_40810 19a7cfd8f9101361ef2a763fdf9458cf 349 Pfam PF02615 Malate/L-lactate dehydrogenase 14 345 5.9E-95 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 A4R43_08375 4b80dd48309a2ef6cebfaba738a28a8f 304 SUPERFAMILY SSF69318 32 279 3.01E-25 T 14-10-2018 A4R43_31610 ddc4affa1d0a44776b397231c83615eb 273 Gene3D G3DSA:3.20.20.30 120 272 1.5E-14 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_31610 ddc4affa1d0a44776b397231c83615eb 273 Gene3D G3DSA:3.20.20.30 7 119 6.3E-12 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_31610 ddc4affa1d0a44776b397231c83615eb 273 SUPERFAMILY SSF51679 12 270 9.25E-37 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_31610 ddc4affa1d0a44776b397231c83615eb 273 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 5 271 2.9E-110 T 14-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted A4R43_31610 ddc4affa1d0a44776b397231c83615eb 273 Pfam PF00296 Luciferase-like monooxygenase 13 116 8.5E-12 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_31610 ddc4affa1d0a44776b397231c83615eb 273 Pfam PF00296 Luciferase-like monooxygenase 129 251 3.5E-5 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_14005 8ca2343af6b6d3d69bfb71388ca24d08 387 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 314 386 9.5E-10 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A4R43_14005 8ca2343af6b6d3d69bfb71388ca24d08 387 Pfam PF01938 TRAM domain 6 53 6.2E-8 T 14-10-2018 IPR002792 TRAM domain A4R43_14005 8ca2343af6b6d3d69bfb71388ca24d08 387 Gene3D G3DSA:3.40.50.150 192 387 5.4E-47 T 14-10-2018 A4R43_14005 8ca2343af6b6d3d69bfb71388ca24d08 387 SUPERFAMILY SSF53335 69 386 1.67E-47 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_14005 8ca2343af6b6d3d69bfb71388ca24d08 387 Gene3D G3DSA:2.40.50.140 2 80 1.0E-20 T 14-10-2018 A4R43_14005 8ca2343af6b6d3d69bfb71388ca24d08 387 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 371 381 - T 14-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A4R43_14005 8ca2343af6b6d3d69bfb71388ca24d08 387 SUPERFAMILY SSF50249 6 53 8.57E-11 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_35625 47c49da3ce0c613de88163833d8db5a7 267 SUPERFAMILY SSF52096 15 266 1.66E-80 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_35625 47c49da3ce0c613de88163833d8db5a7 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 266 4.2E-61 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_35625 47c49da3ce0c613de88163833d8db5a7 267 Gene3D G3DSA:3.90.226.10 4 209 2.4E-68 T 14-10-2018 A4R43_35625 47c49da3ce0c613de88163833d8db5a7 267 Gene3D G3DSA:1.10.12.10 210 267 5.3E-19 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 Gene3D G3DSA:2.40.110.10 129 241 1.3E-43 T 14-10-2018 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 Gene3D G3DSA:1.20.140.10 242 387 1.7E-46 T 14-10-2018 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 4.3E-44 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 Gene3D G3DSA:1.10.540.10 6 124 2.3E-28 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 SUPERFAMILY SSF56645 9 248 2.88E-72 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 225 3.2E-26 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 121 3.7E-23 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 SUPERFAMILY SSF47203 235 386 5.32E-51 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_27970 ce9714194c0bc40da1c1b37fb2b2cb15 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_05445 1d1248cc611362c733e2fa626df55960 356 SMART SM00091 8 75 2.8E-5 T 14-10-2018 IPR000014 PAS domain A4R43_05445 1d1248cc611362c733e2fa626df55960 356 Gene3D G3DSA:3.30.565.10 214 344 1.6E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_05445 1d1248cc611362c733e2fa626df55960 356 SUPERFAMILY SSF55874 220 343 2.06E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_05445 1d1248cc611362c733e2fa626df55960 356 SMART SM00387 249 346 2.7E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_05445 1d1248cc611362c733e2fa626df55960 356 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 344 7.9E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_05445 1d1248cc611362c733e2fa626df55960 356 Gene3D G3DSA:3.30.450.20 6 149 1.1E-27 T 14-10-2018 A4R43_05445 1d1248cc611362c733e2fa626df55960 356 Pfam PF13426 PAS domain 20 123 2.0E-12 T 14-10-2018 IPR000014 PAS domain A4R43_05445 1d1248cc611362c733e2fa626df55960 356 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 131 4.0E-20 T 14-10-2018 IPR000014 PAS domain A4R43_05445 1d1248cc611362c733e2fa626df55960 356 SUPERFAMILY SSF55785 21 131 1.82E-25 T 14-10-2018 IPR035965 PAS domain superfamily A4R43_05445 1d1248cc611362c733e2fa626df55960 356 Pfam PF07730 Histidine kinase 148 212 3.8E-10 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 Gene3D G3DSA:3.20.20.120 129 361 1.0E-154 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 111 136 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 Gene3D G3DSA:3.30.390.10 8 364 1.0E-154 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 136 8.3E-15 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 SUPERFAMILY SSF51604 124 365 2.1E-73 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 SUPERFAMILY SSF54826 7 138 5.95E-30 T 14-10-2018 A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 203 234 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 Pfam PF13378 Enolase C-terminal domain-like 159 363 1.4E-62 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_10120 06f9bfa7160cbdd34133aabee008dedc 378 SMART SM00922 156 253 5.9E-26 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 14-10-2018 IPR018253 DnaJ domain, conserved site A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 SUPERFAMILY SSF46565 3 90 4.45E-30 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 PRINTS PR00625 DnaJ domain signature 60 79 6.5E-23 T 14-10-2018 IPR001623 DnaJ domain A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 PRINTS PR00625 DnaJ domain signature 40 60 6.5E-23 T 14-10-2018 IPR001623 DnaJ domain A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 PRINTS PR00625 DnaJ domain signature 24 39 6.5E-23 T 14-10-2018 IPR001623 DnaJ domain A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 PRINTS PR00625 DnaJ domain signature 6 24 6.5E-23 T 14-10-2018 IPR001623 DnaJ domain A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 Pfam PF01556 DnaJ C terminal domain 152 299 1.6E-34 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 Pfam PF00226 DnaJ domain 4 65 7.3E-27 T 14-10-2018 IPR001623 DnaJ domain A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 Gene3D G3DSA:1.10.287.110 1 146 4.7E-31 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 SUPERFAMILY SSF49493 226 309 9.55E-21 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 SMART SM00271 3 60 1.7E-29 T 14-10-2018 IPR001623 DnaJ domain A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 Gene3D G3DSA:2.60.260.20 147 219 1.8E-23 T 14-10-2018 A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 Gene3D G3DSA:2.60.260.20 221 321 1.3E-27 T 14-10-2018 A4R43_29445 71f60d0bba3fb1b767be0ea6618c79cb 330 SUPERFAMILY SSF49493 146 233 8.37E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4R43_04675 d09e4e8a14ece19317e3fe05925a57c1 304 SUPERFAMILY SSF55729 1 151 8.65E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_04675 d09e4e8a14ece19317e3fe05925a57c1 304 Gene3D G3DSA:3.10.180.10 160 296 2.6E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_04675 d09e4e8a14ece19317e3fe05925a57c1 304 Pfam PF13302 Acetyltransferase (GNAT) domain 9 146 8.1E-24 T 14-10-2018 IPR000182 GNAT domain A4R43_04675 d09e4e8a14ece19317e3fe05925a57c1 304 SUPERFAMILY SSF54593 171 300 3.33E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_04675 d09e4e8a14ece19317e3fe05925a57c1 304 Gene3D G3DSA:3.40.630.30 1 159 4.8E-37 T 14-10-2018 A4R43_04675 d09e4e8a14ece19317e3fe05925a57c1 304 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 173 282 7.1E-15 T 14-10-2018 A4R43_26495 96cef528d149a6539f453d58df7ac5e5 180 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 8.1E-14 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_26495 96cef528d149a6539f453d58df7ac5e5 180 Gene3D G3DSA:1.10.10.10 1 88 2.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26495 96cef528d149a6539f453d58df7ac5e5 180 SUPERFAMILY SSF46785 3 176 1.3E-46 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26495 96cef528d149a6539f453d58df7ac5e5 180 Pfam PF10400 Virulence activator alpha C-term 92 176 3.0E-26 T 14-10-2018 IPR018309 Transcription regulator PadR, C-terminal A4R43_03860 ff9b4a26bbea64d4acd0d5214d6b181b 179 Gene3D G3DSA:1.20.1290.10 37 177 2.8E-35 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_03860 ff9b4a26bbea64d4acd0d5214d6b181b 179 Pfam PF02627 Carboxymuconolactone decarboxylase family 44 125 3.6E-14 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_03860 ff9b4a26bbea64d4acd0d5214d6b181b 179 SUPERFAMILY SSF69118 4 178 2.88E-38 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_22590 48755d5e567b5d5de7afdace33aca7c6 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 300 3.0E-46 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1241 1315 2.5E-20 T 14-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 SUPERFAMILY SSF69304 821 1145 7.45E-7 T 14-10-2018 A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 Gene3D G3DSA:3.90.930.1 768 945 7.1E-16 T 14-10-2018 A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 Gene3D G3DSA:3.90.930.1 577 708 4.7E-13 T 14-10-2018 A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 Gene3D G3DSA:2.180.10.10 1089 1315 6.1E-22 T 14-10-2018 A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 644 683 6.3E-7 T 14-10-2018 IPR006530 YD repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 538 574 1.2E-7 T 14-10-2018 IPR006530 YD repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 831 871 6.6E-12 T 14-10-2018 IPR006530 YD repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 602 643 1.1E-9 T 14-10-2018 IPR006530 YD repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1098 1136 6.1E-6 T 14-10-2018 IPR006530 YD repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1060 1094 3.0E-5 T 14-10-2018 IPR006530 YD repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 624 661 1.5E-9 T 14-10-2018 IPR006530 YD repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 873 912 4.5E-10 T 14-10-2018 IPR006530 YD repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 PRINTS PR00394 RHS protein signature 1283 1302 6.9E-9 T 14-10-2018 IPR001826 RHS protein A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 PRINTS PR00394 RHS protein signature 1260 1280 6.9E-9 T 14-10-2018 IPR001826 RHS protein A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 Pfam PF05593 RHS Repeat 831 867 4.7E-10 T 14-10-2018 IPR031325 RHS repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 Pfam PF05593 RHS Repeat 623 659 6.5E-8 T 14-10-2018 IPR031325 RHS repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 Pfam PF05593 RHS Repeat 1060 1091 5.3E-8 T 14-10-2018 IPR031325 RHS repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 Pfam PF05593 RHS Repeat 873 910 5.2E-9 T 14-10-2018 IPR031325 RHS repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 Pfam PF05593 RHS Repeat 1098 1132 4.3E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 SUPERFAMILY SSF69304 542 682 2.48E-5 T 14-10-2018 A4R43_03495 32287a08133ccf024da511ef6ad0926a 1538 SUPERFAMILY SSF52309 1378 1507 1.19E-7 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.10 1490 1852 9.6E-120 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF47336 952 1021 4.75E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 1666 1911 8.34E-50 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2077 2088 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 1034 1196 4.45E-24 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 1208 1456 1.33E-29 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1326 1477 1.9E-23 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 203 431 2.67E-31 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF47336 2423 2492 1.73E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2454 2469 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00550 Phosphopantetheine attachment site 2433 2493 4.5E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00550 Phosphopantetheine attachment site 961 1021 8.9E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SMART SM00823 Phosphopantetheine attachment site 959 1015 0.0028 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SMART SM00823 Phosphopantetheine attachment site 2430 2498 0.0059 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.30 3094 3326 7.2E-98 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.300.30 853 946 1.2E-24 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.300.30 2322 2416 5.8E-32 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:1.10.1200.10 947 1027 7.7E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:1.10.1200.10 2417 2498 3.2E-20 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 2692 2899 4.45E-29 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 15 195 2.78E-27 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF56801 474 972 9.16E-125 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00668 Condensation domain 2545 2806 6.5E-21 T 14-10-2018 IPR001242 Condensation domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00668 Condensation domain 1485 1921 8.0E-72 T 14-10-2018 IPR001242 Condensation domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00668 Condensation domain 1062 1358 1.3E-34 T 14-10-2018 IPR001242 Condensation domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00668 Condensation domain 2930 3324 3.2E-48 T 14-10-2018 IPR001242 Condensation domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00668 Condensation domain 12 348 5.0E-43 T 14-10-2018 IPR001242 Condensation domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.30 2671 2898 1.1E-49 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.30 1192 1454 4.3E-61 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 2507 2673 1.11E-23 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 3094 3326 1.0E-39 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.10 2941 3277 7.2E-98 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 493 881 5.4E-104 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1962 2351 4.1E-130 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00501 AMP-binding enzyme 477 858 1.3E-78 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF00501 AMP-binding enzyme 1941 2327 2.0E-97 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.30 224 443 9.5E-49 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.30 1666 1917 9.6E-120 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF56801 1900 2442 3.79E-156 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF13193 AMP-binding enzyme C-terminal domain 2335 2405 4.1E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Pfam PF13193 AMP-binding enzyme C-terminal domain 866 936 1.7E-7 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.10 15 218 9.5E-53 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.10 2499 2666 5.8E-38 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.30.559.10 1029 1187 2.0E-29 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 2928 3087 3.11E-35 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 SUPERFAMILY SSF52777 1481 1680 8.0E-40 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.40.50.12780 1931 2321 1.9E-136 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 Gene3D G3DSA:3.40.50.12780 470 852 6.4E-113 T 14-10-2018 A4R43_09885 2a212e11e15f8b78a0c965458a67c76a 3336 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_20565 1e6c4b9c1229c56e8ec79ce5c76527c4 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20565 1e6c4b9c1229c56e8ec79ce5c76527c4 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20565 1e6c4b9c1229c56e8ec79ce5c76527c4 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.2E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20565 1e6c4b9c1229c56e8ec79ce5c76527c4 197 Gene3D G3DSA:1.10.357.10 2 183 1.7E-25 T 14-10-2018 A4R43_20565 1e6c4b9c1229c56e8ec79ce5c76527c4 197 SUPERFAMILY SSF46689 9 75 8.21E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 Pfam PF00106 short chain dehydrogenase 8 189 3.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 4.2E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 4.2E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 4.2E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 6.7E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 6.7E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.7E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 6.7E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 SUPERFAMILY SSF51735 1 266 2.63E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_03415 4fb3e88bedca15c85ba41886c13be22a 273 Gene3D G3DSA:3.40.50.720 5 256 2.6E-51 T 14-10-2018 A4R43_15885 1396da3bb76a69857cc1054218e20b14 542 SUPERFAMILY SSF56801 4 530 9.29E-112 T 14-10-2018 A4R43_15885 1396da3bb76a69857cc1054218e20b14 542 Gene3D G3DSA:3.40.50.12780 2 426 4.2E-81 T 14-10-2018 A4R43_15885 1396da3bb76a69857cc1054218e20b14 542 Gene3D G3DSA:3.30.300.30 428 539 9.5E-26 T 14-10-2018 A4R43_15885 1396da3bb76a69857cc1054218e20b14 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_15885 1396da3bb76a69857cc1054218e20b14 542 Pfam PF00501 AMP-binding enzyme 10 431 6.7E-61 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_15885 1396da3bb76a69857cc1054218e20b14 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 517 1.7E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_20765 228f2891d16f908961416dece8d774c3 132 SUPERFAMILY SSF55620 2 129 1.0E-26 T 14-10-2018 A4R43_20765 228f2891d16f908961416dece8d774c3 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 130 6.7E-21 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A4R43_20765 228f2891d16f908961416dece8d774c3 132 Gene3D G3DSA:3.30.479.10 1 132 3.1E-25 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A4R43_06145 68605088d3e649c79769646431d309f3 299 Pfam PF00106 short chain dehydrogenase 2 135 3.9E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06145 68605088d3e649c79769646431d309f3 299 Gene3D G3DSA:3.40.50.720 1 296 2.6E-45 T 14-10-2018 A4R43_06145 68605088d3e649c79769646431d309f3 299 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 163 191 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_06145 68605088d3e649c79769646431d309f3 299 SUPERFAMILY SSF51735 2 219 1.92E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 SUPERFAMILY SSF55874 274 410 2.33E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 388 8.6E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 407 8.6E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 8.6E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 Gene3D G3DSA:3.30.565.10 279 408 3.2E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 Pfam PF07730 Histidine kinase 216 279 9.3E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 407 7.9E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 SMART SM00387 317 410 6.5E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_14730 b097597e17e38d6bcc1138aa8fefb841 415 PIRSF PIRSF037434 11 414 4.9E-74 T 14-10-2018 IPR017205 Signal transduction histidine kinase, ChrS A4R43_09445 0a684831b91ce4ee03e83d77be9d87a5 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 3.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09445 0a684831b91ce4ee03e83d77be9d87a5 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 3.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09445 0a684831b91ce4ee03e83d77be9d87a5 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 3.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09445 0a684831b91ce4ee03e83d77be9d87a5 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 234 3.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09445 0a684831b91ce4ee03e83d77be9d87a5 277 Pfam PF12697 Alpha/beta hydrolase family 38 267 2.3E-19 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09445 0a684831b91ce4ee03e83d77be9d87a5 277 Gene3D G3DSA:3.40.50.1820 1 274 5.0E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09445 0a684831b91ce4ee03e83d77be9d87a5 277 SUPERFAMILY SSF53474 7 274 1.21E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_18920 14cdf834d90987dee65337dea60564a4 259 SMART SM00448 5 116 8.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_18920 14cdf834d90987dee65337dea60564a4 259 Gene3D G3DSA:3.40.50.2300 2 124 1.1E-29 T 14-10-2018 A4R43_18920 14cdf834d90987dee65337dea60564a4 259 Pfam PF04397 LytTr DNA-binding domain 149 243 1.4E-20 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A4R43_18920 14cdf834d90987dee65337dea60564a4 259 SMART SM00850 148 244 1.0E-29 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A4R43_18920 14cdf834d90987dee65337dea60564a4 259 Pfam PF00072 Response regulator receiver domain 7 116 6.6E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_18920 14cdf834d90987dee65337dea60564a4 259 Gene3D G3DSA:2.40.50.40 140 207 1.5E-5 T 14-10-2018 A4R43_18920 14cdf834d90987dee65337dea60564a4 259 SUPERFAMILY SSF52172 3 121 5.83E-30 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_38850 6e51142ce311c3684e82b12e8107640c 134 Pfam PF01152 Bacterial-like globin 13 130 3.3E-35 T 14-10-2018 IPR001486 Truncated hemoglobin GO:0019825 A4R43_38850 6e51142ce311c3684e82b12e8107640c 134 Gene3D G3DSA:1.10.490.10 9 133 3.6E-48 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4R43_38850 6e51142ce311c3684e82b12e8107640c 134 SUPERFAMILY SSF46458 13 131 3.5E-37 T 14-10-2018 IPR009050 Globin-like superfamily A4R43_17565 ae3d6c567986b256269d77aee216781f 212 SUPERFAMILY SSF55811 3 123 5.82E-28 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_17565 ae3d6c567986b256269d77aee216781f 212 Pfam PF00293 NUDIX domain 6 108 2.0E-11 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_17565 ae3d6c567986b256269d77aee216781f 212 SUPERFAMILY SSF46785 127 194 1.25E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_17565 ae3d6c567986b256269d77aee216781f 212 Gene3D G3DSA:3.90.79.10 1 124 1.1E-28 T 14-10-2018 A4R43_17565 ae3d6c567986b256269d77aee216781f 212 Gene3D G3DSA:1.10.10.10 125 203 1.7E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 Gene3D G3DSA:1.10.240.10 195 305 1.4E-133 T 14-10-2018 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 11 337 8.9E-107 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 SUPERFAMILY SSF52374 12 337 8.23E-99 T 14-10-2018 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 10 338 42.125 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 Gene3D G3DSA:3.40.50.620 13 336 1.4E-133 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 204 214 1.2E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 24 40 1.2E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 74 93 1.2E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 151 172 1.2E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 Pfam PF00579 tRNA synthetases class I (W and Y) 8 292 4.3E-83 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_34645 89491f94bb6661ce0f1f91d656f20d4b 339 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 19 29 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 6.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 6.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 6.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 6.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 Gene3D G3DSA:3.40.50.720 1 244 1.6E-71 T 14-10-2018 A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 181 0.0029 T 14-10-2018 A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 240 1.1E-55 T 14-10-2018 A4R43_21285 e16c695566379f71563deaf0dbf16bd8 246 SUPERFAMILY SSF51735 2 240 2.3E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 Gene3D G3DSA:3.40.50.300 263 421 1.8E-24 T 14-10-2018 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 Gene3D G3DSA:1.10.10.10 2 103 7.2E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SUPERFAMILY SSF46894 9 100 3.68E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 99 9.9E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 Gene3D G3DSA:1.25.40.10 739 927 1.8E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 Pfam PF03704 Bacterial transcriptional activator domain 107 244 1.5E-35 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 PRINTS PR00364 Disease resistance protein signature 379 393 1.8E-6 T 14-10-2018 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 PRINTS PR00364 Disease resistance protein signature 300 315 1.8E-6 T 14-10-2018 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 PRINTS PR00364 Disease resistance protein signature 460 474 1.8E-6 T 14-10-2018 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SMART SM00862 20 100 8.9E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SUPERFAMILY SSF52540 271 532 1.94E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SUPERFAMILY SSF48452 740 910 9.96E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SMART SM01043 107 244 5.2E-40 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 Gene3D G3DSA:1.25.40.10 105 262 1.5E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SMART SM00028 758 791 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SMART SM00028 838 871 3.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SMART SM00028 878 911 390.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SMART SM00028 798 831 68.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 SUPERFAMILY SSF48452 102 265 2.92E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26265 6ed21fe3cd03ae0b017a05f4717bba4e 928 Pfam PF13424 Tetratricopeptide repeat 799 867 1.2E-10 T 14-10-2018 A4R43_00820 0877304d9e98ec43e1adf450b3d54191 332 Gene3D G3DSA:3.40.50.1820 49 331 6.3E-76 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00820 0877304d9e98ec43e1adf450b3d54191 332 Pfam PF00561 alpha/beta hydrolase fold 71 170 5.4E-22 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_00820 0877304d9e98ec43e1adf450b3d54191 332 PRINTS PR00412 Epoxide hydrolase signature 77 95 7.3E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_00820 0877304d9e98ec43e1adf450b3d54191 332 PRINTS PR00412 Epoxide hydrolase signature 141 154 7.3E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_00820 0877304d9e98ec43e1adf450b3d54191 332 SUPERFAMILY SSF53474 47 331 2.34E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_31320 56e78f31034c167164f0a8c3a42308d4 327 SUPERFAMILY SSF161111 11 225 1.44E-36 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4R43_31320 56e78f31034c167164f0a8c3a42308d4 327 Gene3D G3DSA:1.20.1510.10 11 223 2.4E-33 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4R43_31320 56e78f31034c167164f0a8c3a42308d4 327 Pfam PF01545 Cation efflux family 15 221 1.0E-33 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4R43_31320 56e78f31034c167164f0a8c3a42308d4 327 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 304 1.2E-45 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4R43_01495 77488af4210837dd5409b4c1a8dc1917 369 SUPERFAMILY SSF56601 13 340 2.22E-76 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_01495 77488af4210837dd5409b4c1a8dc1917 369 Gene3D G3DSA:3.40.710.10 5 357 2.4E-99 T 14-10-2018 A4R43_01495 77488af4210837dd5409b4c1a8dc1917 369 Pfam PF00144 Beta-lactamase 15 338 1.1E-56 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_20200 95a1b63d4e1d91d1f05531c444dd0b73 573 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 73 141 1.8E-13 T 14-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4R43_20200 95a1b63d4e1d91d1f05531c444dd0b73 573 Pfam PF00703 Glycosyl hydrolases family 2 216 262 1.5E-7 T 14-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 A4R43_20200 95a1b63d4e1d91d1f05531c444dd0b73 573 SUPERFAMILY SSF49785 25 184 2.79E-46 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_20200 95a1b63d4e1d91d1f05531c444dd0b73 573 Gene3D G3DSA:2.60.40.10 186 272 2.0E-10 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_20200 95a1b63d4e1d91d1f05531c444dd0b73 573 Gene3D G3DSA:2.60.120.260 29 184 1.7E-37 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_20200 95a1b63d4e1d91d1f05531c444dd0b73 573 SUPERFAMILY SSF49303 186 272 1.84E-12 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily A4R43_20200 95a1b63d4e1d91d1f05531c444dd0b73 573 SUPERFAMILY SSF51445 269 549 5.32E-56 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_20200 95a1b63d4e1d91d1f05531c444dd0b73 573 Gene3D G3DSA:3.20.20.80 282 563 5.7E-44 T 14-10-2018 A4R43_33880 c204a4cce11617ed6ac93af7fce12bf9 84 SUPERFAMILY SSF46561 9 69 1.44E-21 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33880 c204a4cce11617ed6ac93af7fce12bf9 84 ProSitePatterns PS00579 Ribosomal protein L29 signature. 45 59 - T 14-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33880 c204a4cce11617ed6ac93af7fce12bf9 84 Pfam PF00831 Ribosomal L29 protein 10 66 6.6E-24 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33880 c204a4cce11617ed6ac93af7fce12bf9 84 TIGRFAM TIGR00012 L29: ribosomal protein uL29 11 66 5.5E-19 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33880 c204a4cce11617ed6ac93af7fce12bf9 84 Gene3D G3DSA:1.10.287.310 8 71 6.4E-26 T 14-10-2018 A4R43_33880 c204a4cce11617ed6ac93af7fce12bf9 84 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 7 66 16.415 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.40.50.11460 2791 2930 1.5E-34 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.40.47.10 1620 2066 4.1E-194 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:1.10.1200.10 3531 3623 1.1E-36 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:1.10.1200.10 1519 1609 1.6E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF00698 Acyl transferase domain 2152 2464 2.5E-85 T 14-10-2018 IPR014043 Acyl transferase A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF00698 Acyl transferase domain 563 873 5.5E-54 T 14-10-2018 IPR014043 Acyl transferase A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1625 1875 2.7E-95 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.4E-91 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.40.366.10 561 857 4.4E-164 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.40.366.10 2151 2449 2.5E-161 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF52151 560 853 8.89E-72 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 7.0E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1883 1998 1.4E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 526 8.5E-14 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2001 2116 2.1E-14 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF08659 KR domain 1258 1437 1.2E-62 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF08659 KR domain 3265 3444 1.2E-59 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1788 1804 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF51735 3051 3186 7.66E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF51735 1254 1452 1.68E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00829 2953 3258 4.1E-185 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF55048 687 751 1.03E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 3080 3101 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF51735 2792 2930 2.2E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF08990 Erythronolide synthase docking 2 27 1.3E-9 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF14765 Polyketide synthase dehydratase 2512 2782 1.2E-52 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.30.70.3290 2067 2491 2.5E-161 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF55048 2273 2338 4.84E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00823 Phosphopantetheine attachment site 3548 3620 6.8E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00823 Phosphopantetheine attachment site 1535 1607 4.9E-34 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.40.50.720 3263 3517 3.4E-68 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00825 Beta-ketoacyl synthase 1627 2051 1.1E-229 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00825 Beta-ketoacyl synthase 36 462 6.2E-230 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.90.180.10 2934 3262 5.8E-130 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 2973 3027 4.8E-6 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3265 3445 7.8E-64 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1258 1438 1.1E-61 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF51735 3263 3512 5.68E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF47336 1532 1640 4.32E-27 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF50129 2955 3085 2.04E-29 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF13602 Zinc-binding dehydrogenase 3126 3258 8.5E-18 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF51735 1103 1245 1.38E-20 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF53901 31 406 8.65E-103 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF53901 1622 1996 9.84E-107 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2153 2446 3.9E-117 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 563 854 3.5E-121 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3575 3590 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.40.47.10 30 466 5.3E-189 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF00550 Phosphopantetheine attachment site 1537 1603 1.4E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Pfam PF00550 Phosphopantetheine attachment site 3550 3616 1.4E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1562 1577 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM01294 1536 1603 4.3E-5 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM01294 3549 3616 1.4E-4 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF47336 3540 3627 7.85E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SUPERFAMILY SSF52151 2150 2437 1.41E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.10.129.110 2501 2789 5.3E-113 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.10.129.110 937 1033 3.3E-10 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.40.50.720 1100 1504 1.3E-111 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.30.70.3290 477 902 4.4E-164 T 14-10-2018 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00826 916 1051 3.8E-4 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 SMART SM00826 2512 2674 3.5E-82 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07935 edd93a911f4c567391ee0b3bf9dbe569 3696 Gene3D G3DSA:3.10.129.110 1034 1099 1.1E-6 T 14-10-2018 A4R43_32710 c4586c98705355c86120666f12e2f0c6 79 Pfam PF00462 Glutaredoxin 5 61 4.7E-10 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A4R43_32710 c4586c98705355c86120666f12e2f0c6 79 SUPERFAMILY SSF52833 4 76 3.41E-12 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_32710 c4586c98705355c86120666f12e2f0c6 79 Gene3D G3DSA:3.40.30.10 2 79 1.8E-20 T 14-10-2018 A4R43_35370 324225816ed32d013a6951e8615b083e 415 Gene3D G3DSA:3.30.470.20 115 409 2.2E-26 T 14-10-2018 A4R43_35370 324225816ed32d013a6951e8615b083e 415 SUPERFAMILY SSF56059 101 316 8.66E-24 T 14-10-2018 A4R43_33365 6fcd5979b945ace53f9d9e7f2c3f94b1 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 12 248 1.9E-52 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_33365 6fcd5979b945ace53f9d9e7f2c3f94b1 320 Gene3D G3DSA:3.90.25.10 180 315 8.9E-88 T 14-10-2018 A4R43_33365 6fcd5979b945ace53f9d9e7f2c3f94b1 320 Gene3D G3DSA:3.40.50.720 12 303 8.9E-88 T 14-10-2018 A4R43_33365 6fcd5979b945ace53f9d9e7f2c3f94b1 320 SUPERFAMILY SSF51735 6 318 1.03E-86 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05050 073cc9647cb068295cad6a69cce57d34 392 SUPERFAMILY SSF101960 34 387 8.76E-89 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A4R43_05050 073cc9647cb068295cad6a69cce57d34 392 Pfam PF01458 Uncharacterized protein family (UPF0051) 142 362 1.2E-73 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A4R43_05050 073cc9647cb068295cad6a69cce57d34 392 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 108 379 2.8E-78 T 14-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 199 3.1E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 Pfam PF00072 Response regulator receiver domain 5 113 5.7E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 SMART SM00448 2 115 2.7E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 SUPERFAMILY SSF52172 1 133 9.96E-33 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 Gene3D G3DSA:3.40.50.12740 2 205 2.2E-68 T 14-10-2018 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 1.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 1.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 1.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 SMART SM00421 142 199 9.7E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_14735 d8d18957a4b50248293bd22a35ca1341 208 SUPERFAMILY SSF46894 133 205 1.26E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:3.40.50.720 1237 1685 2.8E-97 T 14-10-2018 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SMART SM00825 Beta-ketoacyl synthase 109 529 4.4E-201 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF47336 1695 1788 7.2E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 264 280 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF53474 1868 2131 4.92E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1444 1612 7.3E-38 T 14-10-2018 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF51735 1442 1675 2.78E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 479 593 1.1E-19 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF00698 Acyl transferase domain 630 938 4.7E-78 T 14-10-2018 IPR014043 Acyl transferase A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF55048 750 813 1.44E-9 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF00975 Thioesterase domain 1880 2005 7.0E-26 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:3.40.366.20 548 939 1.5E-119 T 14-10-2018 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:3.10.129.110 975 1234 1.1E-59 T 14-10-2018 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:3.40.50.1820 1869 2134 2.6E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF47336 1786 1857 8.51E-10 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:1.10.1200.10 13 95 8.1E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:1.10.1200.10 1686 1771 7.6E-13 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF08659 KR domain 1444 1610 8.5E-51 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF47336 18 122 5.89E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 632 934 6.9E-80 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:1.10.1200.10 1777 1863 1.7E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF52151 629 910 3.66E-55 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 359 476 3.3E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SMART SM00826 976 1124 2.8E-42 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1726 1741 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SMART SM00824 Thioesterase 1882 2127 0.0051 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 107 351 1.8E-84 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF00550 Phosphopantetheine attachment site 1703 1767 3.0E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF00550 Phosphopantetheine attachment site 25 89 1.3E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:3.40.47.10 100 547 6.8E-183 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF53901 106 525 7.17E-99 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Pfam PF14765 Polyketide synthase dehydratase 976 1233 1.1E-55 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SUPERFAMILY SSF51735 1240 1432 1.84E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 Gene3D G3DSA:3.30.70.250 748 814 1.5E-119 T 14-10-2018 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SMART SM00823 Phosphopantetheine attachment site 1700 1771 4.7E-12 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_35350 2198dbcc214e9afb84cdb039416fad05 2151 SMART SM00823 Phosphopantetheine attachment site 23 94 3.7E-13 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 Gene3D G3DSA:1.10.10.10 2 93 8.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 Gene3D G3DSA:1.25.40.10 372 647 1.2E-38 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SUPERFAMILY SSF48452 404 509 4.03E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SMART SM00862 16 90 6.3E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SMART SM00028 558 591 9.7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SMART SM00028 598 631 44.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SMART SM00028 518 551 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SMART SM00028 438 471 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 Gene3D G3DSA:1.25.40.10 95 257 8.9E-42 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 90 2.2E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SUPERFAMILY SSF48452 93 255 6.07E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SUPERFAMILY SSF46894 5 90 2.13E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SUPERFAMILY SSF48452 495 633 7.97E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 Pfam PF03704 Bacterial transcriptional activator domain 98 241 7.4E-41 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_20860 9ed86e97bf494a3227c56c1c557676a9 649 SMART SM01043 97 241 7.0E-43 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_19995 ab40088493cfb517c70234895cd62e0b 168 Gene3D G3DSA:3.30.70.1150 84 163 8.6E-29 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A4R43_19995 ab40088493cfb517c70234895cd62e0b 168 Gene3D G3DSA:3.30.70.260 1 79 1.1E-36 T 14-10-2018 A4R43_19995 ab40088493cfb517c70234895cd62e0b 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 159 3.1E-63 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4R43_19995 ab40088493cfb517c70234895cd62e0b 168 SUPERFAMILY SSF55021 3 75 5.24E-24 T 14-10-2018 A4R43_19995 ab40088493cfb517c70234895cd62e0b 168 Pfam PF10369 Small subunit of acetolactate synthase 85 158 2.3E-27 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4R43_19995 ab40088493cfb517c70234895cd62e0b 168 Pfam PF01842 ACT domain 4 69 6.5E-18 T 14-10-2018 IPR002912 ACT domain A4R43_19995 ab40088493cfb517c70234895cd62e0b 168 SUPERFAMILY SSF55021 81 162 3.21E-25 T 14-10-2018 A4R43_19995 ab40088493cfb517c70234895cd62e0b 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 74 7.0E-30 T 14-10-2018 A4R43_32820 4728b5285140c718e9d23a6ca6aeb646 273 SUPERFAMILY SSF54637 161 269 8.95E-7 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_32820 4728b5285140c718e9d23a6ca6aeb646 273 Pfam PF13622 Thioesterase-like superfamily 28 269 1.3E-41 T 14-10-2018 A4R43_32820 4728b5285140c718e9d23a6ca6aeb646 273 SUPERFAMILY SSF54637 14 123 8.91E-9 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_32820 4728b5285140c718e9d23a6ca6aeb646 273 Gene3D G3DSA:3.10.129.90 5 271 1.9E-75 T 14-10-2018 A4R43_17705 a394b77fdbbc5972498a99e67f890d03 138 SUPERFAMILY SSF52172 35 130 1.11E-7 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_17705 a394b77fdbbc5972498a99e67f890d03 138 Gene3D G3DSA:3.40.50.2300 3 132 7.9E-8 T 14-10-2018 A4R43_36885 2b9e40b142011efeca0b0f38fdb00f5e 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 184 1.3E-22 T 14-10-2018 A4R43_36885 2b9e40b142011efeca0b0f38fdb00f5e 227 SUPERFAMILY SSF56784 5 214 1.44E-45 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_36885 2b9e40b142011efeca0b0f38fdb00f5e 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 50 184 2.6E-16 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_36885 2b9e40b142011efeca0b0f38fdb00f5e 227 Gene3D G3DSA:1.10.150.240 16 86 7.2E-48 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_36885 2b9e40b142011efeca0b0f38fdb00f5e 227 Gene3D G3DSA:3.40.50.1000 6 189 7.2E-48 T 14-10-2018 IPR023214 HAD superfamily A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 PRINTS PR00359 B-class P450 signature 147 162 2.6E-19 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 PRINTS PR00359 B-class P450 signature 198 220 2.6E-19 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 PRINTS PR00359 B-class P450 signature 130 146 2.6E-19 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 PRINTS PR00359 B-class P450 signature 280 291 2.6E-19 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 PRINTS PR00359 B-class P450 signature 326 341 2.6E-19 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 PRINTS PR00359 B-class P450 signature 298 325 2.6E-19 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 PRINTS PR00359 B-class P450 signature 347 356 2.6E-19 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 Gene3D G3DSA:1.10.630.10 8 407 6.2E-80 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 Pfam PF00067 Cytochrome P450 279 374 5.3E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_00755 4269c8b496f23948d05a5de9107abcb4 407 SUPERFAMILY SSF48264 19 406 1.83E-65 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Gene3D G3DSA:3.40.50.880 290 419 5.4E-30 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Gene3D G3DSA:3.40.50.880 34 228 9.1E-23 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Pfam PF00754 F5/8 type C domain 169 280 1.0E-10 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Pfam PF06439 Domain of Unknown Function (DUF1080) 1104 1316 6.8E-34 T 14-10-2018 IPR010496 Domain of unknown function DUF1080 A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Gene3D G3DSA:2.60.120.560 1099 1318 4.8E-38 T 14-10-2018 A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 SUPERFAMILY SSF52317 304 415 7.32E-16 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Gene3D G3DSA:2.120.10.30 423 820 4.0E-56 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Pfam PF00801 PKD domain 954 1004 7.0E-8 T 14-10-2018 IPR000601 PKD domain A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 SMART SM00089 940 1019 2.1E-10 T 14-10-2018 IPR022409 PKD/Chitinase domain A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Pfam PF06283 Trehalose utilisation 51 409 8.3E-77 T 14-10-2018 IPR029010 ThuA-like domain A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 SUPERFAMILY SSF50952 441 770 5.49E-14 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 SUPERFAMILY SSF49299 942 1012 2.09E-14 T 14-10-2018 IPR035986 PKD domain superfamily A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 SUPERFAMILY SSF52317 48 170 6.41E-11 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Pfam PF07995 Glucose / Sorbosone dehydrogenase 512 737 2.0E-21 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 Gene3D G3DSA:2.60.40.10 939 1017 1.4E-16 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_32335 032a6628d235dd9dafb8b215bd191454 1318 SUPERFAMILY SSF49785 163 294 3.6E-15 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 890 906 2.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 906 918 2.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 876 890 2.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 SUPERFAMILY SSF52540 22 252 6.6E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 Pfam PF13191 AAA ATPase domain 10 169 6.1E-19 T 14-10-2018 A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 Pfam PF00196 Bacterial regulatory proteins, luxR family 874 928 1.5E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 Gene3D G3DSA:1.10.10.10 794 936 5.6E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 SUPERFAMILY SSF46894 864 928 9.18E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 SMART SM00421 873 930 1.5E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05370 8654746f5865c1dc626f351bb1b5091f 939 ProSitePatterns PS00622 LuxR-type HTH domain signature. 890 917 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20965 d37c1f7e1fe8a6bebd4a2b89872e67f4 198 SUPERFAMILY SSF49329 73 192 1.44E-10 T 14-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4R43_20965 d37c1f7e1fe8a6bebd4a2b89872e67f4 198 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 65 192 2.3E-9 T 14-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4R43_20965 d37c1f7e1fe8a6bebd4a2b89872e67f4 198 Gene3D G3DSA:2.60.40.200 26 195 1.6E-12 T 14-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4R43_09395 339baa2a324db038ba8388268e6a4acf 87 SUPERFAMILY SSF53335 26 56 2.65E-5 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_19385 37ca66fec1c8fe64523e8d117421acc7 243 Gene3D G3DSA:3.40.1080.10 1 242 3.8E-81 T 14-10-2018 A4R43_19385 37ca66fec1c8fe64523e8d117421acc7 243 SMART SM00882 1 210 8.1E-35 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_19385 37ca66fec1c8fe64523e8d117421acc7 243 Pfam PF01144 Coenzyme A transferase 1 209 1.4E-39 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_19385 37ca66fec1c8fe64523e8d117421acc7 243 SUPERFAMILY SSF100950 1 238 3.84E-71 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 SUPERFAMILY SSF49785 416 521 1.28E-22 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 341 351 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 SUPERFAMILY SSF52743 125 403 3.4E-76 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 Gene3D G3DSA:3.30.70.80 38 117 4.3E-18 T 14-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 Gene3D G3DSA:2.60.120.260 405 521 4.8E-11 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 153 164 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 Pfam PF01483 Proprotein convertase P-domain 443 520 5.7E-20 T 14-10-2018 IPR002884 P domain GO:0004252|GO:0006508 A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 SUPERFAMILY SSF54897 45 116 5.04E-13 T 14-10-2018 A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 Pfam PF00082 Subtilase family 155 376 6.7E-35 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 Pfam PF05922 Peptidase inhibitor I9 47 116 4.5E-7 T 14-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 Gene3D G3DSA:3.40.50.200 121 397 1.5E-89 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 PRINTS PR00723 Subtilisin serine protease family (S8) signature 148 167 2.0E-16 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 199 2.0E-16 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 PRINTS PR00723 Subtilisin serine protease family (S8) signature 340 356 2.0E-16 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_23055 28c0428137d75cb194cde2b2343a1145 521 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 190 200 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_37505 527a8473c55f827777158f51eb773ae3 590 SUPERFAMILY SSF49265 394 490 1.13E-15 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_37505 527a8473c55f827777158f51eb773ae3 590 SMART SM00060 405 483 6.5E-9 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_37505 527a8473c55f827777158f51eb773ae3 590 Pfam PF00041 Fibronectin type III domain 407 484 1.5E-9 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_37505 527a8473c55f827777158f51eb773ae3 590 Gene3D G3DSA:2.60.40.10 400 496 1.2E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_37505 527a8473c55f827777158f51eb773ae3 590 SUPERFAMILY SSF82171 131 336 4.32E-5 T 14-10-2018 A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 SUPERFAMILY SSF52743 91 482 2.66E-61 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 421 431 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 125 135 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 Pfam PF00082 Subtilase family 262 472 3.0E-24 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 158 171 1.1E-11 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 420 436 1.1E-11 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 120 139 1.1E-11 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 162 172 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 Gene3D G3DSA:3.40.50.200 228 485 3.4E-55 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 Gene3D G3DSA:3.40.50.200 49 225 8.7E-32 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_34040 9f1aa5cf069572d04c5c8457077a07b9 557 Pfam PF00082 Subtilase family 123 197 1.1E-9 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 115 2.6E-33 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 SUPERFAMILY SSF51246 335 450 1.52E-35 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 SUPERFAMILY SSF52096 1282 1499 1.39E-21 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 328 1.4E-63 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 292 299 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Pfam PF00364 Biotin-requiring enzyme 590 655 2.6E-9 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Pfam PF02785 Biotin carboxylase C-terminal domain 340 449 1.5E-34 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Gene3D G3DSA:2.40.50.100 583 656 2.5E-15 T 14-10-2018 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Pfam PF08326 Acetyl-CoA carboxylase, central region 1016 1206 1.0E-15 T 14-10-2018 IPR013537 Acetyl-CoA carboxylase, central domain GO:0003989|GO:0005524|GO:0006633 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-163765|Reactome: R-HSA-196780|Reactome: R-HSA-200425|Reactome: R-HSA-2426168 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Gene3D G3DSA:3.90.226.10 1515 1824 5.7E-57 T 14-10-2018 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 SUPERFAMILY SSF52096 1549 1823 3.98E-37 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 SUPERFAMILY SSF51230 581 656 8.25E-15 T 14-10-2018 IPR011053 Single hybrid motif A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 SUPERFAMILY SSF52440 2 118 2.59E-33 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Pfam PF01039 Carboxyl transferase domain 1332 1821 3.2E-31 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 SMART SM00878 340 448 7.8E-50 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 SUPERFAMILY SSF56059 88 329 4.77E-61 T 14-10-2018 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Gene3D G3DSA:3.30.470.130 1 452 3.3E-174 T 14-10-2018 A4R43_11650 8ea1722821cc94ca3e0d97a20d4ceaa1 1824 Gene3D G3DSA:3.90.226.10 1256 1506 1.5E-36 T 14-10-2018 A4R43_01925 f33f52bd87ba8271f7999acfe3352b4d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 3.2E-14 T 14-10-2018 A4R43_01925 f33f52bd87ba8271f7999acfe3352b4d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.2E-14 T 14-10-2018 A4R43_01925 f33f52bd87ba8271f7999acfe3352b4d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 3.2E-14 T 14-10-2018 A4R43_01925 f33f52bd87ba8271f7999acfe3352b4d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 3.2E-14 T 14-10-2018 A4R43_01925 f33f52bd87ba8271f7999acfe3352b4d 392 Gene3D G3DSA:3.50.50.60 5 334 3.6E-68 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_01925 f33f52bd87ba8271f7999acfe3352b4d 392 Pfam PF01494 FAD binding domain 3 312 4.7E-18 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_01925 f33f52bd87ba8271f7999acfe3352b4d 392 SUPERFAMILY SSF51905 1 363 8.29E-59 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_01925 f33f52bd87ba8271f7999acfe3352b4d 392 Gene3D G3DSA:3.30.9.50 38 264 3.6E-68 T 14-10-2018 A4R43_09910 f7297f2bb6ba93c8299f5fff043f1d07 287 Pfam PF08021 Siderophore-interacting FAD-binding domain 36 146 1.9E-27 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting A4R43_09910 f7297f2bb6ba93c8299f5fff043f1d07 287 SUPERFAMILY SSF63380 29 147 1.08E-11 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_09910 f7297f2bb6ba93c8299f5fff043f1d07 287 Gene3D G3DSA:2.40.30.10 18 147 2.8E-41 T 14-10-2018 A4R43_09910 f7297f2bb6ba93c8299f5fff043f1d07 287 Pfam PF04954 Siderophore-interacting protein 155 274 1.4E-37 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain A4R43_09910 f7297f2bb6ba93c8299f5fff043f1d07 287 Gene3D G3DSA:3.40.50.80 149 287 1.4E-45 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_18415 4e26f5ec6fa22ac130daabf0e0de7b9d 391 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 73 301 5.0E-61 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A4R43_18415 4e26f5ec6fa22ac130daabf0e0de7b9d 391 Pfam PF02481 DNA recombination-mediator protein A 74 291 2.8E-65 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A4R43_18415 4e26f5ec6fa22ac130daabf0e0de7b9d 391 SUPERFAMILY SSF102405 112 301 1.02E-31 T 14-10-2018 A4R43_18415 4e26f5ec6fa22ac130daabf0e0de7b9d 391 Gene3D G3DSA:3.40.50.450 2 305 1.3E-87 T 14-10-2018 A4R43_32485 423b8c3a32cb89c074baa123091dfa6f 465 Pfam PF00083 Sugar (and other) transporter 29 233 5.4E-29 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_32485 423b8c3a32cb89c074baa123091dfa6f 465 Pfam PF07690 Major Facilitator Superfamily 288 438 4.8E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_32485 423b8c3a32cb89c074baa123091dfa6f 465 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_32485 423b8c3a32cb89c074baa123091dfa6f 465 Gene3D G3DSA:1.20.1250.20 22 452 4.2E-64 T 14-10-2018 A4R43_32485 423b8c3a32cb89c074baa123091dfa6f 465 SUPERFAMILY SSF103473 11 442 7.06E-65 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 7.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 7.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 Pfam PF00155 Aminotransferase class I and II 133 394 3.2E-8 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 86 1.2E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 SMART SM00345 29 88 4.1E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 SUPERFAMILY SSF53383 97 466 1.32E-71 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 Gene3D G3DSA:1.10.10.10 12 89 4.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 Gene3D G3DSA:3.40.640.10 99 460 1.3E-102 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_03190 41283e7965a1a62dbe14222e5c7b755c 480 SUPERFAMILY SSF46785 18 98 3.11E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03770 56ba4ff5f32833e996d010ce9d25cc65 236 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_03770 56ba4ff5f32833e996d010ce9d25cc65 236 Gene3D G3DSA:3.40.50.300 1 226 4.8E-60 T 14-10-2018 A4R43_03770 56ba4ff5f32833e996d010ce9d25cc65 236 SMART SM00382 26 212 7.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03770 56ba4ff5f32833e996d010ce9d25cc65 236 SUPERFAMILY SSF52540 2 224 2.55E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_03770 56ba4ff5f32833e996d010ce9d25cc65 236 Pfam PF00005 ABC transporter 17 162 7.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 SUPERFAMILY SSF102114 499 802 4.71E-44 T 14-10-2018 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 Gene3D G3DSA:3.20.20.70 11 319 1.4E-54 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 Gene3D G3DSA:3.20.20.70 490 837 1.4E-48 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 73 397 3.2E-146 T 14-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 496 836 1.5E-154 T 14-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 528 835 3.1E-109 T 14-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 Pfam PF04055 Radical SAM superfamily 536 696 3.7E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 SUPERFAMILY SSF102114 33 374 2.88E-39 T 14-10-2018 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 SMART SM00729 76 310 1.2E-5 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 Pfam PF04055 Radical SAM superfamily 80 259 3.1E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 Hamap MF_01612 FO synthase subunit 2 [cofH]. 481 839 47.716 T 14-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 A4R43_34635 a9f0691b837d28edf52f51fd12322b40 843 Hamap MF_01611 FO synthase subunit 1 [cofG]. 72 399 50.316 T 14-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 A4R43_25805 a961e29d08b907e5b2db3b50995830d7 390 SUPERFAMILY SSF51905 16 382 4.99E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_25805 a961e29d08b907e5b2db3b50995830d7 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 5.8E-21 T 14-10-2018 A4R43_25805 a961e29d08b907e5b2db3b50995830d7 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 331 5.8E-21 T 14-10-2018 A4R43_25805 a961e29d08b907e5b2db3b50995830d7 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 5.8E-21 T 14-10-2018 A4R43_25805 a961e29d08b907e5b2db3b50995830d7 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 5.8E-21 T 14-10-2018 A4R43_25805 a961e29d08b907e5b2db3b50995830d7 390 Gene3D G3DSA:3.50.50.60 15 388 2.3E-69 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_25805 a961e29d08b907e5b2db3b50995830d7 390 Pfam PF13450 NAD(P)-binding Rossmann-like domain 19 49 2.1E-5 T 14-10-2018 A4R43_25805 a961e29d08b907e5b2db3b50995830d7 390 Pfam PF01494 FAD binding domain 296 353 2.8E-8 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Gene3D G3DSA:3.40.50.12780 1 402 2.2E-116 T 14-10-2018 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Gene3D G3DSA:3.40.50.12780 1044 1445 1.8E-114 T 14-10-2018 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 23 433 6.4E-113 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1076 1475 1.0E-114 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 487 5.5E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Pfam PF13193 AMP-binding enzyme C-terminal domain 1459 1531 4.4E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 SUPERFAMILY SSF56801 1047 1572 6.93E-135 T 14-10-2018 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Gene3D G3DSA:1.10.1200.10 502 591 1.1E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 ProSitePatterns PS00012 Phosphopantetheine attachment site. 541 556 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Gene3D G3DSA:3.30.300.30 403 501 1.7E-24 T 14-10-2018 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Gene3D G3DSA:3.30.300.30 1446 1546 7.3E-28 T 14-10-2018 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 SUPERFAMILY SSF47336 1555 1624 1.57E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Gene3D G3DSA:3.30.559.10 606 963 1.2E-114 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Gene3D G3DSA:3.30.559.30 776 1018 1.2E-114 T 14-10-2018 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Pfam PF00501 AMP-binding enzyme 3 409 2.5E-81 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Pfam PF00501 AMP-binding enzyme 1057 1451 1.8E-80 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 SUPERFAMILY SSF56801 1 529 5.49E-123 T 14-10-2018 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 SUPERFAMILY SSF52777 779 1022 1.22E-48 T 14-10-2018 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 SUPERFAMILY SSF47336 512 590 1.57E-11 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Pfam PF00668 Condensation domain 606 1030 8.6E-77 T 14-10-2018 IPR001242 Condensation domain A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1194 1205 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Pfam PF00550 Phosphopantetheine attachment site 521 582 2.5E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Pfam PF00550 Phosphopantetheine attachment site 1561 1621 4.2E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 Gene3D G3DSA:1.10.1200.10 1547 1632 4.7E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 SMART SM00823 Phosphopantetheine attachment site 518 586 2.7E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 SMART SM00823 Phosphopantetheine attachment site 1559 1628 4.0E-6 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_02205 ea61534e4e84a75823c5d9b40c0a01e7 1647 SUPERFAMILY SSF52777 608 772 1.22E-39 T 14-10-2018 A4R43_20330 f108482463a1b547b29b65607e87cc06 264 SUPERFAMILY SSF55961 104 260 3.5E-30 T 14-10-2018 A4R43_20330 f108482463a1b547b29b65607e87cc06 264 Pfam PF12840 Helix-turn-helix domain 2 62 4.2E-16 T 14-10-2018 A4R43_20330 f108482463a1b547b29b65607e87cc06 264 Gene3D G3DSA:1.10.10.10 1 104 1.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20330 f108482463a1b547b29b65607e87cc06 264 Gene3D G3DSA:3.30.530.20 107 264 9.1E-33 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_20330 f108482463a1b547b29b65607e87cc06 264 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 117 254 4.7E-21 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_20330 f108482463a1b547b29b65607e87cc06 264 SMART SM00418 3 86 2.8E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_20330 f108482463a1b547b29b65607e87cc06 264 SUPERFAMILY SSF46785 1 99 1.71E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_34185 2e7222127fabc2b099a04edc8a176fa8 266 SMART SM00420 14 66 1.1E-4 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_34185 2e7222127fabc2b099a04edc8a176fa8 266 SUPERFAMILY SSF46785 12 70 5.73E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_34185 2e7222127fabc2b099a04edc8a176fa8 266 SMART SM01134 81 241 2.0E-49 T 14-10-2018 A4R43_34185 2e7222127fabc2b099a04edc8a176fa8 266 ProSitePatterns PS00894 DeoR-type HTH domain signature. 14 48 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_34185 2e7222127fabc2b099a04edc8a176fa8 266 SUPERFAMILY SSF100950 83 242 1.03E-19 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_34185 2e7222127fabc2b099a04edc8a176fa8 266 Pfam PF08220 DeoR-like helix-turn-helix domain 14 64 4.8E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_34185 2e7222127fabc2b099a04edc8a176fa8 266 Pfam PF00455 DeoR C terminal sensor domain 85 239 1.0E-39 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_37585 64cbb0f8def8c0325194664b290bb21c 170 Pfam PF05534 HicB family 105 136 1.6E-5 T 14-10-2018 IPR008651 Uncharacterised protein family HicB A4R43_37585 64cbb0f8def8c0325194664b290bb21c 170 Gene3D G3DSA:1.10.1220.10 102 142 5.0E-7 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A4R43_37585 64cbb0f8def8c0325194664b290bb21c 170 SUPERFAMILY SSF47598 101 152 2.0E-11 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4R43_01690 88f672d3bfbbca02e28b581f82c14807 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 4.4E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01690 88f672d3bfbbca02e28b581f82c14807 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01690 88f672d3bfbbca02e28b581f82c14807 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01690 88f672d3bfbbca02e28b581f82c14807 190 Gene3D G3DSA:1.10.357.10 3 187 3.5E-35 T 14-10-2018 A4R43_01690 88f672d3bfbbca02e28b581f82c14807 190 SUPERFAMILY SSF46689 7 81 1.8E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01690 88f672d3bfbbca02e28b581f82c14807 190 SUPERFAMILY SSF48498 97 186 1.21E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_20875 a3e8fcb50913672afd57974c36a93900 238 SUPERFAMILY SSF52540 2 197 6.56E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20875 a3e8fcb50913672afd57974c36a93900 238 Gene3D G3DSA:3.40.50.300 1 201 7.4E-36 T 14-10-2018 A4R43_20875 a3e8fcb50913672afd57974c36a93900 238 Pfam PF00005 ABC transporter 19 148 2.4E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_20875 a3e8fcb50913672afd57974c36a93900 238 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_20875 a3e8fcb50913672afd57974c36a93900 238 SMART SM00382 27 202 3.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05935 1b0a66297ef817a1c9ae43524408f90e 171 Gene3D G3DSA:2.70.50.50 32 171 2.4E-50 T 14-10-2018 A4R43_05935 1b0a66297ef817a1c9ae43524408f90e 171 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 168 1.8E-16 T 14-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal A4R43_05935 1b0a66297ef817a1c9ae43524408f90e 171 SUPERFAMILY SSF81296 32 170 4.06E-34 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 PRINTS PR00364 Disease resistance protein signature 279 294 2.5E-6 T 14-10-2018 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 PRINTS PR00364 Disease resistance protein signature 444 458 2.5E-6 T 14-10-2018 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 PRINTS PR00364 Disease resistance protein signature 357 371 2.5E-6 T 14-10-2018 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SMART SM00028 690 723 0.6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SMART SM00028 770 803 0.72 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SMART SM00028 850 883 5.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SMART SM00028 810 843 0.55 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SMART SM00028 730 763 7.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SMART SM01043 104 239 1.2E-44 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SUPERFAMILY SSF48452 688 881 1.08E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SUPERFAMILY SSF46894 10 97 4.82E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Pfam PF00486 Transcriptional regulatory protein, C terminal 36 85 5.0E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Gene3D G3DSA:1.10.10.10 2 99 7.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SMART SM00862 27 97 0.0072 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Gene3D G3DSA:1.25.40.10 756 899 1.2E-29 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Pfam PF00931 NB-ARC domain 281 516 3.1E-7 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SUPERFAMILY SSF52540 259 514 2.39E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 SUPERFAMILY SSF48452 101 258 6.35E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Gene3D G3DSA:1.25.40.10 102 262 2.9E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Gene3D G3DSA:1.25.40.10 662 755 8.3E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Pfam PF03704 Bacterial transcriptional activator domain 105 239 1.2E-34 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Pfam PF13424 Tetratricopeptide repeat 773 842 9.3E-15 T 14-10-2018 A4R43_32910 e23a44e40711977806b369dbc0e324ea 899 Pfam PF13424 Tetratricopeptide repeat 689 761 9.4E-11 T 14-10-2018 A4R43_24610 35fccdb270240abec5c7e4ef186c946f 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 42 176 6.9E-9 T 14-10-2018 A4R43_24610 35fccdb270240abec5c7e4ef186c946f 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 172 2.9E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_24610 35fccdb270240abec5c7e4ef186c946f 214 Gene3D G3DSA:3.40.50.1000 1 213 8.7E-28 T 14-10-2018 IPR023214 HAD superfamily A4R43_24610 35fccdb270240abec5c7e4ef186c946f 214 SUPERFAMILY SSF56784 1 207 2.81E-34 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_10595 2561c07c9613aa8167928778242e5b09 267 SUPERFAMILY SSF49899 25 246 7.34E-21 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_10595 2561c07c9613aa8167928778242e5b09 267 Gene3D G3DSA:2.60.120.200 24 259 1.1E-22 T 14-10-2018 A4R43_10595 2561c07c9613aa8167928778242e5b09 267 Pfam PF00722 Glycosyl hydrolases family 16 87 243 6.0E-8 T 14-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 SMART SM01390 3 90 1.2E-42 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 14-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 Gene3D G3DSA:3.10.290.10 90 186 3.9E-73 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.773 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 SUPERFAMILY SSF55174 3 201 2.62E-65 T 14-10-2018 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 1.0E-28 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 1.1E-78 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 Gene3D G3DSA:1.10.1050.10 6 201 3.9E-73 T 14-10-2018 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 SMART SM00363 91 156 8.0E-16 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33990 3dd71d4ed265829162c6d94a6ca42155 201 Pfam PF01479 S4 domain 92 138 2.6E-19 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_31195 3b7f547606ac5b8bc53523dd5896b279 97 SMART SM00883 1 85 1.3E-20 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_31195 3b7f547606ac5b8bc53523dd5896b279 97 Pfam PF00166 Chaperonin 10 Kd subunit 1 84 7.7E-17 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_31195 3b7f547606ac5b8bc53523dd5896b279 97 SUPERFAMILY SSF50129 2 85 1.83E-18 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_31195 3b7f547606ac5b8bc53523dd5896b279 97 Gene3D G3DSA:2.30.33.40 1 87 1.2E-13 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 A4R43_02355 8b47b3ea1fb3f0690b92f85a8a96d191 536 Gene3D G3DSA:3.40.50.12780 10 405 6.9E-102 T 14-10-2018 A4R43_02355 8b47b3ea1fb3f0690b92f85a8a96d191 536 Pfam PF00501 AMP-binding enzyme 21 413 8.5E-67 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_02355 8b47b3ea1fb3f0690b92f85a8a96d191 536 SUPERFAMILY SSF56801 13 505 1.44E-111 T 14-10-2018 A4R43_02355 8b47b3ea1fb3f0690b92f85a8a96d191 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 493 5.5E-6 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_02355 8b47b3ea1fb3f0690b92f85a8a96d191 536 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 41 436 1.2E-99 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_02355 8b47b3ea1fb3f0690b92f85a8a96d191 536 Gene3D G3DSA:3.30.300.30 408 519 1.1E-27 T 14-10-2018 A4R43_09510 986070c98d60ad110ee4f8f84f1f5139 548 SUPERFAMILY SSF51556 57 496 3.84E-29 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_09510 986070c98d60ad110ee4f8f84f1f5139 548 Pfam PF07969 Amidohydrolase family 46 539 3.0E-89 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_09510 986070c98d60ad110ee4f8f84f1f5139 548 Gene3D G3DSA:3.10.310.70 76 192 3.2E-132 T 14-10-2018 A4R43_09510 986070c98d60ad110ee4f8f84f1f5139 548 SUPERFAMILY SSF51338 2 539 1.47E-22 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_09510 986070c98d60ad110ee4f8f84f1f5139 548 Gene3D G3DSA:2.30.40.10 5 516 3.2E-132 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_09510 986070c98d60ad110ee4f8f84f1f5139 548 Gene3D G3DSA:3.20.20.140 58 498 3.2E-132 T 14-10-2018 A4R43_21410 ab21ef12c56ec2825bea68f7a3c01273 227 SMART SM00862 145 217 2.3E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_21410 ab21ef12c56ec2825bea68f7a3c01273 227 SUPERFAMILY SSF52172 2 170 9.81E-34 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_21410 ab21ef12c56ec2825bea68f7a3c01273 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 217 2.8E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_21410 ab21ef12c56ec2825bea68f7a3c01273 227 Gene3D G3DSA:3.40.50.2300 1 121 5.4E-30 T 14-10-2018 A4R43_21410 ab21ef12c56ec2825bea68f7a3c01273 227 Pfam PF00072 Response regulator receiver domain 3 112 1.8E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_21410 ab21ef12c56ec2825bea68f7a3c01273 227 SMART SM00448 1 112 1.0E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_21410 ab21ef12c56ec2825bea68f7a3c01273 227 Gene3D G3DSA:1.10.10.10 126 223 2.6E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 Pfam PF03129 Anticodon binding domain 490 578 6.1E-17 T 14-10-2018 IPR004154 Anticodon-binding A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 577 1.3E-169 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 Gene3D G3DSA:3.90.960.10 242 402 2.8E-213 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 4.4E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 4.4E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 4.4E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 4.4E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 Gene3D G3DSA:3.40.50.800 5 565 2.8E-213 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 Gene3D G3DSA:3.30.930.10 13 478 2.8E-213 T 14-10-2018 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 SUPERFAMILY SSF52954 477 580 4.58E-28 T 14-10-2018 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 SUPERFAMILY SSF55826 254 392 2.88E-10 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 581 36.711 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 SUPERFAMILY SSF55681 12 491 3.32E-87 T 14-10-2018 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 Pfam PF04073 Aminoacyl-tRNA editing domain 259 392 5.1E-23 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4R43_18180 f3cbb70fe9773821f06e954ca46ad7e7 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 472 9.1E-39 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_14720 e42f6602fcb8c4e28cc941ef33dc3223 247 PIRSF PIRSF006648 6 247 2.2E-21 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_14720 e42f6602fcb8c4e28cc941ef33dc3223 247 Pfam PF01061 ABC-2 type transporter 7 214 2.2E-24 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_30120 5c72c67fee8c1f20ef1c84823973dfe2 421 SUPERFAMILY SSF58104 201 346 5.23E-5 T 14-10-2018 A4R43_30120 5c72c67fee8c1f20ef1c84823973dfe2 421 Pfam PF02470 MlaD protein 61 136 6.8E-10 T 14-10-2018 IPR003399 Mce/MlaD A4R43_05145 24b4a166baacdc5659fd179a7eacdee4 231 Pfam PF12697 Alpha/beta hydrolase family 21 198 1.3E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_05145 24b4a166baacdc5659fd179a7eacdee4 231 SUPERFAMILY SSF53474 11 202 2.18E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_05145 24b4a166baacdc5659fd179a7eacdee4 231 Gene3D G3DSA:3.40.50.1820 3 206 4.0E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 Gene3D G3DSA:2.40.10.10 225 347 1.2E-45 T 14-10-2018 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 Pfam PF13180 PDZ domain 351 417 3.2E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 Pfam PF13365 Trypsin-like peptidase domain 160 305 1.9E-32 T 14-10-2018 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 SMART SM00228 350 421 3.3E-13 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 PRINTS PR00834 HtrA/DegQ protease family signature 235 259 1.9E-49 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 PRINTS PR00834 HtrA/DegQ protease family signature 194 214 1.9E-49 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 PRINTS PR00834 HtrA/DegQ protease family signature 379 391 1.9E-49 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 PRINTS PR00834 HtrA/DegQ protease family signature 298 315 1.9E-49 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 PRINTS PR00834 HtrA/DegQ protease family signature 169 181 1.9E-49 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 PRINTS PR00834 HtrA/DegQ protease family signature 276 293 1.9E-49 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 SUPERFAMILY SSF50494 134 345 4.35E-57 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 Gene3D G3DSA:2.30.42.10 348 432 8.2E-23 T 14-10-2018 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 Gene3D G3DSA:2.40.10.10 127 224 3.5E-32 T 14-10-2018 A4R43_25035 1afecdcc5756f0ed916cffc234af704b 435 SUPERFAMILY SSF50156 321 420 2.63E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 A4R43_16395 e8b8bfaa97b3fec610a908f80a29a591 238 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 88 234 2.3E-24 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_16395 e8b8bfaa97b3fec610a908f80a29a591 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 1.3E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16395 e8b8bfaa97b3fec610a908f80a29a591 238 Gene3D G3DSA:1.10.10.60 3 80 2.9E-28 T 14-10-2018 A4R43_16395 e8b8bfaa97b3fec610a908f80a29a591 238 SUPERFAMILY SSF46689 19 82 6.48E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_16395 e8b8bfaa97b3fec610a908f80a29a591 238 Gene3D G3DSA:1.10.357.10 82 236 1.2E-36 T 14-10-2018 A4R43_16395 e8b8bfaa97b3fec610a908f80a29a591 238 SUPERFAMILY SSF48498 91 236 2.35E-25 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_37825 8dc43f9949e6c6f79ef1a41640243541 314 SUPERFAMILY SSF50486 205 307 5.49E-20 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 A4R43_37825 8dc43f9949e6c6f79ef1a41640243541 314 Pfam PF02911 Formyl transferase, C-terminal domain 205 305 5.0E-17 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_37825 8dc43f9949e6c6f79ef1a41640243541 314 Pfam PF00551 Formyl transferase 1 168 8.2E-32 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_37825 8dc43f9949e6c6f79ef1a41640243541 314 Gene3D G3DSA:3.40.50.12230 1 309 2.4E-86 T 14-10-2018 A4R43_37825 8dc43f9949e6c6f79ef1a41640243541 314 SUPERFAMILY SSF53328 1 202 2.62E-56 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 TIGRFAM TIGR03356 BGL: beta-galactosidase 6 433 1.4E-168 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 SUPERFAMILY SSF51445 5 441 5.36E-153 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 Pfam PF00232 Glycosyl hydrolase family 1 5 441 3.8E-140 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 PRINTS PR00131 Glycosyl hydrolase family 1 signature 387 404 5.5E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 PRINTS PR00131 Glycosyl hydrolase family 1 signature 345 353 5.5E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 423 5.5E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 PRINTS PR00131 Glycosyl hydrolase family 1 signature 366 377 5.5E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 PRINTS PR00131 Glycosyl hydrolase family 1 signature 280 294 5.5E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A4R43_28940 fa1ccd943d9b4aab97b0413dc61406a1 442 Gene3D G3DSA:3.20.20.80 1 442 1.5E-164 T 14-10-2018 A4R43_11225 d4099f8f14ecd9717ebdb0645b349f4f 270 Pfam PF13560 Helix-turn-helix domain 10 71 2.2E-10 T 14-10-2018 A4R43_11225 d4099f8f14ecd9717ebdb0645b349f4f 270 SMART SM00530 13 68 5.4E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_11225 d4099f8f14ecd9717ebdb0645b349f4f 270 Gene3D G3DSA:1.10.260.40 7 76 1.8E-10 T 14-10-2018 A4R43_11225 d4099f8f14ecd9717ebdb0645b349f4f 270 SUPERFAMILY SSF47413 8 67 3.22E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 PRINTS PR00364 Disease resistance protein signature 204 218 6.2E-10 T 14-10-2018 A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 PRINTS PR00364 Disease resistance protein signature 43 58 6.2E-10 T 14-10-2018 A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 PRINTS PR00364 Disease resistance protein signature 117 131 6.2E-10 T 14-10-2018 A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 Gene3D G3DSA:1.25.40.10 367 666 8.7E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 SUPERFAMILY SSF52540 11 268 5.61E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 SMART SM00382 40 172 5.1E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 Gene3D G3DSA:3.40.50.300 7 163 7.0E-25 T 14-10-2018 A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 SUPERFAMILY SSF48452 559 661 2.66E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21525 70d9d63315d72c8dbcc8639427e2c084 669 Pfam PF00931 NB-ARC domain 27 223 1.2E-9 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_16315 cf1d6e65c0439b5c07a7fff62eb207e2 480 Pfam PF00221 Aromatic amino acid lyase 9 436 1.7E-116 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A4R43_16315 cf1d6e65c0439b5c07a7fff62eb207e2 480 Gene3D G3DSA:1.10.275.10 1 186 1.8E-38 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal A4R43_16315 cf1d6e65c0439b5c07a7fff62eb207e2 480 SUPERFAMILY SSF48557 2 478 5.1E-119 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4R43_16315 cf1d6e65c0439b5c07a7fff62eb207e2 480 Gene3D G3DSA:1.20.200.10 187 480 1.4E-79 T 14-10-2018 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Pfam PF00550 Phosphopantetheine attachment site 928 990 1.6E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 SUPERFAMILY SSF56801 404 938 1.1E-135 T 14-10-2018 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Gene3D G3DSA:1.10.1200.10 916 1001 4.6E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Pfam PF13193 AMP-binding enzyme C-terminal domain 828 899 5.4E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Gene3D G3DSA:3.40.50.12780 428 812 5.3E-118 T 14-10-2018 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 460 843 2.7E-114 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 ProSitePatterns PS00455 Putative AMP-binding domain signature. 575 586 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Pfam PF00668 Condensation domain 2 417 1.4E-64 T 14-10-2018 IPR001242 Condensation domain A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 SMART SM00823 Phosphopantetheine attachment site 926 994 6.5E-12 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Gene3D G3DSA:3.30.559.30 165 404 1.6E-108 T 14-10-2018 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Gene3D G3DSA:3.30.300.30 815 913 1.3E-27 T 14-10-2018 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 SUPERFAMILY SSF47336 920 991 1.44E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Pfam PF00501 AMP-binding enzyme 440 820 4.0E-84 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 Gene3D G3DSA:3.30.559.10 4 348 1.6E-108 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 SUPERFAMILY SSF52777 5 171 4.45E-40 T 14-10-2018 A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 ProSitePatterns PS00012 Phosphopantetheine attachment site. 949 964 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_08335 9feac09e803e988ac8a94e5704c40c94 1022 SUPERFAMILY SSF52777 166 425 1.67E-48 T 14-10-2018 A4R43_40470 146999eb22db750329c07d43efa7011a 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 188 7.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_40470 146999eb22db750329c07d43efa7011a 218 Gene3D G3DSA:3.40.50.12740 8 213 1.9E-28 T 14-10-2018 A4R43_40470 146999eb22db750329c07d43efa7011a 218 SUPERFAMILY SSF52172 7 134 8.82E-14 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_40470 146999eb22db750329c07d43efa7011a 218 SMART SM00448 7 119 1.6E-5 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_40470 146999eb22db750329c07d43efa7011a 218 Pfam PF00072 Response regulator receiver domain 10 120 1.2E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_40470 146999eb22db750329c07d43efa7011a 218 SUPERFAMILY SSF46894 142 214 2.82E-10 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_15475 880d270b1d3da11bd39c82d96857d634 364 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15475 880d270b1d3da11bd39c82d96857d634 364 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15475 880d270b1d3da11bd39c82d96857d634 364 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15475 880d270b1d3da11bd39c82d96857d634 364 SUPERFAMILY SSF46689 4 72 5.13E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_15475 880d270b1d3da11bd39c82d96857d634 364 Gene3D G3DSA:1.10.357.10 1 195 5.5E-22 T 14-10-2018 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SUPERFAMILY SSF52151 565 858 5.49E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SUPERFAMILY SSF47336 1614 1701 1.15E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Gene3D G3DSA:1.10.1200.10 1602 1695 8.4E-37 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 867 3.6E-114 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1649 1664 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Pfam PF00550 Phosphopantetheine attachment site 1624 1689 1.2E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 2.4E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Gene3D G3DSA:3.30.70.3290 475 915 2.5E-163 T 14-10-2018 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SUPERFAMILY SSF51735 1213 1332 9.84E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SMART SM00823 Phosphopantetheine attachment site 1622 1694 2.4E-33 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SUPERFAMILY SSF51735 1344 1574 1.59E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SUPERFAMILY SSF101173 2 34 9.42E-6 T 14-10-2018 IPR036299 Polyketide synthase, docking domain superfmaily A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 5.9E-91 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Pfam PF08659 KR domain 1345 1520 6.6E-55 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 525 4.9E-21 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SUPERFAMILY SSF53901 31 404 1.78E-102 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Pfam PF00698 Acyl transferase domain 566 886 1.5E-85 T 14-10-2018 IPR014043 Acyl transferase A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Pfam PF14765 Polyketide synthase dehydratase 933 1203 4.6E-58 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Gene3D G3DSA:3.40.47.10 30 464 4.4E-190 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SMART SM01294 1623 1690 1.9E-6 T 14-10-2018 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SUPERFAMILY SSF55048 691 756 3.53E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Gene3D G3DSA:3.40.50.720 1211 1595 3.8E-117 T 14-10-2018 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1345 1521 5.0E-50 T 14-10-2018 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SMART SM00826 933 1096 7.5E-77 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 SMART SM00825 Beta-ketoacyl synthase 36 460 2.2E-229 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Gene3D G3DSA:3.10.129.110 924 1210 7.6E-103 T 14-10-2018 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Pfam PF08990 Erythronolide synthase docking 2 27 4.5E-11 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_37735 3429cf0531d7a27e79bfbd582211175d 1767 Gene3D G3DSA:3.40.366.10 566 870 2.5E-163 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 SUPERFAMILY SSF54980 608 694 1.63E-30 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 696 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 SUPERFAMILY SSF54980 406 483 6.83E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Pfam PF14492 Elongation Factor G, domain II 406 480 6.1E-34 T 14-10-2018 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Gene3D G3DSA:3.30.230.10 486 692 1.4E-88 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Gene3D G3DSA:3.30.70.240 609 679 1.4E-88 T 14-10-2018 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 SMART SM00889 482 603 5.1E-71 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 3.4E-36 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Hamap MF_00054_B Elongation factor G [fusA]. 8 696 110.77 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 PRINTS PR00315 GTP-binding elongation factor signature 80 90 6.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 PRINTS PR00315 GTP-binding elongation factor signature 60 68 6.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 PRINTS PR00315 GTP-binding elongation factor signature 96 107 6.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Pfam PF03144 Elongation factor Tu domain 2 326 393 3.7E-14 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Gene3D G3DSA:3.40.50.300 5 296 1.4E-113 T 14-10-2018 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Pfam PF00679 Elongation factor G C-terminus 605 691 7.7E-31 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 SUPERFAMILY SSF50447 267 406 1.19E-33 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Pfam PF03764 Elongation factor G, domain IV 481 603 2.4E-46 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Gene3D G3DSA:2.40.30.10 297 407 7.6E-42 T 14-10-2018 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 SMART SM00838 605 692 1.3E-58 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Pfam PF00009 Elongation factor Tu GTP binding domain 11 284 1.1E-67 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 Gene3D G3DSA:3.30.70.870 408 485 1.6E-31 T 14-10-2018 A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 SUPERFAMILY SSF54211 481 604 1.37E-39 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_33825 0cde8bf74818c1b4c40141c0f7e57b50 699 SUPERFAMILY SSF52540 8 284 5.86E-108 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17975 e62a793ad7fd341c9f379fabb629126e 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 60 5.4E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17975 e62a793ad7fd341c9f379fabb629126e 208 SUPERFAMILY SSF46689 6 68 1.7E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17975 e62a793ad7fd341c9f379fabb629126e 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 6.0E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17975 e62a793ad7fd341c9f379fabb629126e 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.0E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17975 e62a793ad7fd341c9f379fabb629126e 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_17975 e62a793ad7fd341c9f379fabb629126e 208 Gene3D G3DSA:1.10.10.60 6 55 4.9E-22 T 14-10-2018 A4R43_17975 e62a793ad7fd341c9f379fabb629126e 208 Gene3D G3DSA:1.10.357.10 57 201 1.2E-26 T 14-10-2018 A4R43_23190 d788b1af1396b9c7470a66ed27cc2083 257 SMART SM00967 16 93 1.3E-8 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A4R43_23190 d788b1af1396b9c7470a66ed27cc2083 257 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 17 91 6.2E-12 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A4R43_23190 d788b1af1396b9c7470a66ed27cc2083 257 Gene3D G3DSA:3.30.1330.30 6 89 1.2E-6 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_23190 d788b1af1396b9c7470a66ed27cc2083 257 SUPERFAMILY SSF55315 10 87 3.77E-9 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_23190 d788b1af1396b9c7470a66ed27cc2083 257 SUPERFAMILY SSF75217 100 254 9.16E-39 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_23190 d788b1af1396b9c7470a66ed27cc2083 257 Gene3D G3DSA:3.40.1280.10 91 254 3.6E-41 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_23190 d788b1af1396b9c7470a66ed27cc2083 257 Pfam PF00588 SpoU rRNA Methylase family 109 248 4.9E-32 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 SMART SM01134 79 239 1.8E-43 T 14-10-2018 A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 SMART SM00420 12 64 1.9E-11 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 Pfam PF00455 DeoR C terminal sensor domain 81 235 4.1E-37 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 Pfam PF08220 DeoR-like helix-turn-helix domain 12 64 8.9E-12 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 SUPERFAMILY SSF46785 10 77 1.12E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 SUPERFAMILY SSF100950 81 235 3.66E-17 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 1.9E-5 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 1.9E-5 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_36875 4cff5fe23548fe46b78f9ec8793264f5 262 Gene3D G3DSA:1.10.10.10 2 65 4.9E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19015 6a741ad58c8a4dffe1fca2e24095959e 331 SUPERFAMILY SSF53098 171 317 8.19E-24 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_19015 6a741ad58c8a4dffe1fca2e24095959e 331 ProSitePatterns PS01043 Transposases, IS30 family, signature. 265 281 - T 14-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 A4R43_19015 6a741ad58c8a4dffe1fca2e24095959e 331 Pfam PF13936 Helix-turn-helix domain 1 40 2.4E-15 T 14-10-2018 IPR025246 Transposase IS30-like HTH domain A4R43_19015 6a741ad58c8a4dffe1fca2e24095959e 331 Pfam PF00665 Integrase core domain 171 278 2.4E-10 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 Gene3D G3DSA:3.20.20.300 1 390 1.5E-96 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 SUPERFAMILY SSF52279 407 576 5.89E-24 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 PRINTS PR00133 Glycosyl hydrolase family 3 signature 201 217 1.1E-12 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 PRINTS PR00133 Glycosyl hydrolase family 3 signature 280 298 1.1E-12 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 PRINTS PR00133 Glycosyl hydrolase family 3 signature 165 181 1.1E-12 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 PRINTS PR00133 Glycosyl hydrolase family 3 signature 88 104 1.1E-12 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 PRINTS PR00133 Glycosyl hydrolase family 3 signature 119 138 1.1E-12 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 SUPERFAMILY SSF51445 2 406 2.84E-77 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 492 576 1.7E-12 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 Gene3D G3DSA:3.40.50.1700 467 578 1.0E-16 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_09475 a33c80188cfa702f1abbc05fcc6636c6 579 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 70 366 1.7E-41 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_02145 7e399e8c9aa04318ca9f64a6e8f5d618 406 Gene3D G3DSA:3.30.1540.10 240 331 1.1E-130 T 14-10-2018 A4R43_02145 7e399e8c9aa04318ca9f64a6e8f5d618 406 SUPERFAMILY SSF89796 6 406 3.66E-133 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_02145 7e399e8c9aa04318ca9f64a6e8f5d618 406 Gene3D G3DSA:3.40.50.10540 9 400 1.1E-130 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_02145 7e399e8c9aa04318ca9f64a6e8f5d618 406 Pfam PF02515 CoA-transferase family III 10 383 1.4E-128 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Gene3D G3DSA:3.30.559.30 765 1006 8.1E-137 T 14-10-2018 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Gene3D G3DSA:3.40.50.12780 1 397 9.8E-140 T 14-10-2018 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 SUPERFAMILY SSF52777 772 1006 1.78E-52 T 14-10-2018 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 SUPERFAMILY SSF47336 505 576 1.57E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Pfam PF00501 AMP-binding enzyme 8 403 6.3E-98 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 SUPERFAMILY SSF52777 595 761 1.08E-49 T 14-10-2018 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Gene3D G3DSA:3.30.300.30 398 499 2.4E-35 T 14-10-2018 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 SMART SM00823 Phosphopantetheine attachment site 511 580 5.7E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 485 1.6E-15 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 ProSitePatterns PS00012 Phosphopantetheine attachment site. 535 550 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Gene3D G3DSA:3.30.559.10 594 955 8.1E-137 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Gene3D G3DSA:1.10.1200.10 500 581 1.1E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 SUPERFAMILY SSF56801 4 524 1.23E-150 T 14-10-2018 A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Pfam PF00550 Phosphopantetheine attachment site 513 576 2.7E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 29 427 1.5E-132 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_08305 cee735c5e0af0d8c91050ea66f11eeae 1009 Pfam PF00668 Condensation domain 593 1005 3.1E-90 T 14-10-2018 IPR001242 Condensation domain A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 SUPERFAMILY SSF55424 347 463 1.08E-26 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 Gene3D G3DSA:3.50.50.60 155 273 1.1E-107 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 Gene3D G3DSA:3.30.390.30 341 462 1.4E-35 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.0E-50 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 SUPERFAMILY SSF51905 3 337 6.32E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PIRSF PIRSF000350 1 457 2.5E-75 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 456 2.1E-23 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 Gene3D G3DSA:3.50.50.60 4 331 1.1E-107 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 2.7E-61 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 3.1E-34 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 3.1E-34 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 3.1E-34 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 3.1E-34 T 14-10-2018 A4R43_35000 8e3808933573af31a166187c6d2f8bff 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.1E-34 T 14-10-2018 A4R43_22650 1261ccd99a3251db094635f73022ea90 315 SUPERFAMILY SSF53474 49 312 2.53E-72 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22650 1261ccd99a3251db094635f73022ea90 315 Gene3D G3DSA:3.40.50.1820 5 315 2.7E-94 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22650 1261ccd99a3251db094635f73022ea90 315 Pfam PF07859 alpha/beta hydrolase fold 80 288 5.5E-72 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_13530 d4b1cbd5d057ac4610f070b27470773b 472 SUPERFAMILY SSF56529 5 205 9.16E-59 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_13530 d4b1cbd5d057ac4610f070b27470773b 472 Gene3D G3DSA:3.50.30.100 223 441 6.3E-52 T 14-10-2018 A4R43_13530 d4b1cbd5d057ac4610f070b27470773b 472 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 12 206 2.2E-51 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_13530 d4b1cbd5d057ac4610f070b27470773b 472 Pfam PF03737 Aldolase/RraA 256 418 1.5E-30 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A4R43_13530 d4b1cbd5d057ac4610f070b27470773b 472 Gene3D G3DSA:3.90.850.10 1 204 4.7E-61 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_13530 d4b1cbd5d057ac4610f070b27470773b 472 SUPERFAMILY SSF89562 253 427 9.68E-37 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily A4R43_09205 8f2d171dc14210a406fe887341d5087b 440 Pfam PF07687 Peptidase dimerisation domain 201 324 9.0E-14 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_09205 8f2d171dc14210a406fe887341d5087b 440 Pfam PF01546 Peptidase family M20/M25/M40 84 438 2.3E-36 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_09205 8f2d171dc14210a406fe887341d5087b 440 SUPERFAMILY SSF55031 204 325 1.13E-10 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_09205 8f2d171dc14210a406fe887341d5087b 440 Gene3D G3DSA:3.40.630.10 5 207 8.0E-50 T 14-10-2018 A4R43_09205 8f2d171dc14210a406fe887341d5087b 440 PIRSF PIRSF036696 6 247 3.1E-29 T 14-10-2018 A4R43_09205 8f2d171dc14210a406fe887341d5087b 440 PIRSF PIRSF036696 281 439 2.3E-9 T 14-10-2018 A4R43_09205 8f2d171dc14210a406fe887341d5087b 440 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 83 92 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4R43_09205 8f2d171dc14210a406fe887341d5087b 440 SUPERFAMILY SSF53187 6 438 2.73E-54 T 14-10-2018 A4R43_07780 4680dfa9b70465e1d7c99b0e8f85f5bd 578 Gene3D G3DSA:3.40.50.300 326 573 2.7E-82 T 14-10-2018 A4R43_07780 4680dfa9b70465e1d7c99b0e8f85f5bd 578 Pfam PF00664 ABC transporter transmembrane region 53 287 3.5E-15 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_07780 4680dfa9b70465e1d7c99b0e8f85f5bd 578 SMART SM00382 356 542 5.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_07780 4680dfa9b70465e1d7c99b0e8f85f5bd 578 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_07780 4680dfa9b70465e1d7c99b0e8f85f5bd 578 Gene3D G3DSA:1.20.1560.10 12 318 1.0E-35 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_07780 4680dfa9b70465e1d7c99b0e8f85f5bd 578 Pfam PF00005 ABC transporter 347 496 1.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_07780 4680dfa9b70465e1d7c99b0e8f85f5bd 578 SUPERFAMILY SSF52540 321 564 7.54E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_07780 4680dfa9b70465e1d7c99b0e8f85f5bd 578 SUPERFAMILY SSF90123 16 322 3.14E-44 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_34950 1031dee64987c76d3edd51773e0e2ed9 387 SUPERFAMILY SSF53756 2 383 4.4E-65 T 14-10-2018 A4R43_34950 1031dee64987c76d3edd51773e0e2ed9 387 Gene3D G3DSA:3.40.50.2000 205 367 3.0E-105 T 14-10-2018 A4R43_34950 1031dee64987c76d3edd51773e0e2ed9 387 Gene3D G3DSA:3.40.50.2000 2 376 3.0E-105 T 14-10-2018 A4R43_34950 1031dee64987c76d3edd51773e0e2ed9 387 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 268 336 1.0E-10 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Gene3D G3DSA:3.10.20.590 885 945 3.6E-20 T 14-10-2018 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 290 483 2.7E-57 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Gene3D G3DSA:3.10.330.110 690 736 3.9E-196 T 14-10-2018 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Gene3D G3DSA:3.40.50.620 211 686 3.9E-196 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Pfam PF09334 tRNA synthetases class I (M) 61 167 2.5E-13 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 SUPERFAMILY SSF50677 296 494 1.15E-44 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 216 945 3.7E-216 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 SUPERFAMILY SSF52374 20 759 5.03E-109 T 14-10-2018 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Gene3D G3DSA:3.40.50.620 53 179 2.8E-41 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 15 945 21.495 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 PRINTS PR00985 Leucyl-tRNA synthetase signature 631 653 2.2E-53 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 PRINTS PR00985 Leucyl-tRNA synthetase signature 284 303 2.2E-53 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 PRINTS PR00985 Leucyl-tRNA synthetase signature 255 268 2.2E-53 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 PRINTS PR00985 Leucyl-tRNA synthetase signature 149 166 2.2E-53 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 PRINTS PR00985 Leucyl-tRNA synthetase signature 664 674 2.2E-53 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 PRINTS PR00985 Leucyl-tRNA synthetase signature 222 238 2.2E-53 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 PRINTS PR00985 Leucyl-tRNA synthetase signature 579 597 2.2E-53 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Gene3D G3DSA:3.90.740.10 304 507 3.9E-196 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 SUPERFAMILY SSF47323 757 944 7.85E-35 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Gene3D G3DSA:1.10.730.10 737 884 3.9E-196 T 14-10-2018 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 65 75 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_30615 54aa09fe4f64640ee88be39a6c0a41c7 945 Pfam PF08264 Anticodon-binding domain of tRNA 794 909 3.2E-15 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A4R43_12380 bb1a48550a417d1dd19c754befcfd5a2 170 Pfam PF13556 PucR C-terminal helix-turn-helix domain 101 156 6.0E-17 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_12380 bb1a48550a417d1dd19c754befcfd5a2 170 Gene3D G3DSA:1.10.10.2840 32 161 4.3E-19 T 14-10-2018 A4R43_03075 25cb212a5e9d9a7de0d2bf8f473dc001 458 Pfam PF01979 Amidohydrolase family 95 449 1.4E-21 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_03075 25cb212a5e9d9a7de0d2bf8f473dc001 458 SUPERFAMILY SSF51556 98 412 1.15E-41 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_03075 25cb212a5e9d9a7de0d2bf8f473dc001 458 SUPERFAMILY SSF51338 37 450 4.13E-22 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_03075 25cb212a5e9d9a7de0d2bf8f473dc001 458 Gene3D G3DSA:2.30.40.10 49 447 2.0E-63 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_03075 25cb212a5e9d9a7de0d2bf8f473dc001 458 Gene3D G3DSA:3.20.20.140 99 424 2.0E-63 T 14-10-2018 A4R43_01555 ee4b6f5f5fe75b4752e26595bd37c451 384 SUPERFAMILY SSF52283 8 179 1.79E-27 T 14-10-2018 A4R43_01555 ee4b6f5f5fe75b4752e26595bd37c451 384 SUPERFAMILY SSF51735 144 318 3.28E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_01555 ee4b6f5f5fe75b4752e26595bd37c451 384 Gene3D G3DSA:3.40.50.720 9 365 6.4E-49 T 14-10-2018 A4R43_01555 ee4b6f5f5fe75b4752e26595bd37c451 384 SMART SM01002 147 312 1.6E-15 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4R43_01555 ee4b6f5f5fe75b4752e26595bd37c451 384 SMART SM01003 8 144 1.0E-19 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4R43_01555 ee4b6f5f5fe75b4752e26595bd37c451 384 Gene3D G3DSA:3.40.50.720 137 320 6.4E-49 T 14-10-2018 A4R43_01555 ee4b6f5f5fe75b4752e26595bd37c451 384 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 12 125 2.5E-12 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4R43_01555 ee4b6f5f5fe75b4752e26595bd37c451 384 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 234 365 1.1E-10 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 SUPERFAMILY SSF49785 475 627 4.46E-14 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 Gene3D G3DSA:3.40.50.1820 34 246 3.0E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 Gene3D G3DSA:2.60.120.260 465 633 2.9E-14 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 61 200 2.5E-12 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 SUPERFAMILY SSF52540 672 896 2.51E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 SUPERFAMILY SSF53474 39 408 4.78E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 SMART SM00939 397 622 1.4E-5 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 Pfam PF00005 ABC transporter 693 833 5.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 Gene3D G3DSA:3.40.50.300 666 901 1.1E-61 T 14-10-2018 A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 498 609 1.3E-8 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 SMART SM00382 701 881 4.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 Gene3D G3DSA:3.40.50.1820 259 404 5.8E-9 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14680 78f8cf37692e91fa4cd0e9bef05d2ba5 973 ProSitePatterns PS00211 ABC transporters family signature. 805 819 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_29950 1b8ff17e3e1b4fdd77c523ab17d27062 255 SUPERFAMILY SSF52096 2 255 3.27E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_29950 1b8ff17e3e1b4fdd77c523ab17d27062 255 Gene3D G3DSA:3.90.226.10 1 195 8.2E-61 T 14-10-2018 A4R43_29950 1b8ff17e3e1b4fdd77c523ab17d27062 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 254 3.1E-56 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_29950 1b8ff17e3e1b4fdd77c523ab17d27062 255 Gene3D G3DSA:1.10.12.10 198 255 1.0E-17 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 Gene3D G3DSA:3.40.50.300 178 336 6.1E-45 T 14-10-2018 A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 Pfam PF00271 Helicase conserved C-terminal domain 202 319 6.8E-13 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 5 789 5.6E-233 T 14-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 SMART SM00487 3 184 1.8E-14 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 SMART SM00490 200 319 9.6E-16 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 Gene3D G3DSA:3.40.50.300 1 177 2.7E-51 T 14-10-2018 A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 Pfam PF08482 ATP-dependent helicase C-terminal 652 777 2.1E-49 T 14-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 Pfam PF04408 Helicase associated domain (HA2) 383 452 4.8E-11 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 Gene3D G3DSA:1.20.120.1080 366 469 3.2E-9 T 14-10-2018 A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 SUPERFAMILY SSF52540 16 328 2.38E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 SMART SM00847 379 470 9.1E-11 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 A4R43_21795 8d77e063ab4696ff5c321f8aa81cb2dc 790 PIRSF PIRSF005496 1 790 5.4E-269 T 14-10-2018 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 122 332 9.4E-73 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 Gene3D G3DSA:2.40.50.100 596 664 1.2E-21 T 14-10-2018 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 SMART SM00878 345 451 4.1E-52 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 Pfam PF00364 Biotin-requiring enzyme 600 662 8.4E-17 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_29975 24c855df10760e294943ccd5ad5611be 668 SUPERFAMILY SSF52440 5 119 3.96E-46 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_29975 24c855df10760e294943ccd5ad5611be 668 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 162 176 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 Pfam PF00289 Biotin carboxylase, N-terminal domain 8 116 1.3E-41 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 620 637 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 SUPERFAMILY SSF51246 340 453 9.94E-38 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 295 302 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 SUPERFAMILY SSF56059 89 352 4.24E-67 T 14-10-2018 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 Gene3D G3DSA:3.30.470.130 1 457 4.5E-192 T 14-10-2018 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 Pfam PF02785 Biotin carboxylase C-terminal domain 345 451 3.7E-35 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_29975 24c855df10760e294943ccd5ad5611be 668 SUPERFAMILY SSF51230 591 664 4.58E-21 T 14-10-2018 IPR011053 Single hybrid motif A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 Gene3D G3DSA:2.60.40.10 169 255 5.9E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 Pfam PF00754 F5/8 type C domain 42 155 5.0E-24 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 SMART SM00060 171 244 2.5E-10 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 Gene3D G3DSA:2.60.120.260 32 160 2.2E-36 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 Gene3D G3DSA:3.60.21.10 263 513 5.4E-34 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 SUPERFAMILY SSF49785 36 160 1.98E-28 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 SUPERFAMILY SSF56300 284 516 6.69E-40 T 14-10-2018 A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 Pfam PF00149 Calcineurin-like phosphoesterase 281 443 4.7E-7 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_14835 cc519bca1a5a64004f2473d48ac16e49 523 SUPERFAMILY SSF49265 168 257 4.06E-16 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_17215 42e2c831c20b1d2e4e95ff7775392f89 315 Gene3D G3DSA:1.10.3720.10 86 307 3.2E-14 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_17215 42e2c831c20b1d2e4e95ff7775392f89 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 312 8.2E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_17215 42e2c831c20b1d2e4e95ff7775392f89 315 SUPERFAMILY SSF161098 93 297 1.7E-13 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_01560 a5cf96f7745327c9b4c656f9a19b6b37 396 SUPERFAMILY SSF50939 39 391 1.51E-83 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_01560 a5cf96f7745327c9b4c656f9a19b6b37 396 Pfam PF13088 BNR repeat-like domain 62 365 9.5E-36 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_01560 a5cf96f7745327c9b4c656f9a19b6b37 396 Gene3D G3DSA:2.120.10.10 34 393 4.4E-97 T 14-10-2018 A4R43_01820 73ac7f546d5a46ba046bf2e28418f222 201 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 2.3E-49 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4R43_01820 73ac7f546d5a46ba046bf2e28418f222 201 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 182 5.0E-66 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4R43_01820 73ac7f546d5a46ba046bf2e28418f222 201 SUPERFAMILY SSF51182 1 198 1.36E-60 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_01820 73ac7f546d5a46ba046bf2e28418f222 201 Gene3D G3DSA:2.60.120.10 1 201 1.2E-62 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.0E-20 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 478 33.598 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 SUPERFAMILY SSF52540 42 356 8.85E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 SMART SM00382 99 303 4.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 Gene3D G3DSA:1.10.260.30 312 436 7.0E-40 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 SMART SM00962 100 298 3.4E-106 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 Pfam PF02978 Signal peptide binding domain 330 427 4.2E-29 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 Gene3D G3DSA:1.20.120.140 5 308 2.1E-120 T 14-10-2018 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 8.0E-178 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 SUPERFAMILY SSF47446 330 430 5.23E-33 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 3.8E-69 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 Gene3D G3DSA:3.40.50.300 90 287 2.1E-120 T 14-10-2018 A4R43_18485 654e5a6f5d018f7535d02b2eb14487d6 519 SMART SM00963 1 86 1.9E-33 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_14665 b46b2dd4a2f9ead3dfbfd8bcf929c7a0 169 Pfam PF00583 Acetyltransferase (GNAT) family 47 143 1.2E-8 T 14-10-2018 IPR000182 GNAT domain A4R43_14665 b46b2dd4a2f9ead3dfbfd8bcf929c7a0 169 Gene3D G3DSA:3.40.630.30 6 167 5.5E-32 T 14-10-2018 A4R43_14665 b46b2dd4a2f9ead3dfbfd8bcf929c7a0 169 SUPERFAMILY SSF55729 7 150 1.59E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_32815 9686af0f37e94b44419311ee082163af 306 Pfam PF01619 Proline dehydrogenase 45 297 1.0E-28 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 A4R43_32815 9686af0f37e94b44419311ee082163af 306 Gene3D G3DSA:3.20.20.530 20 304 3.9E-88 T 14-10-2018 A4R43_32815 9686af0f37e94b44419311ee082163af 306 PIRSF PIRSF000196 1 306 4.0E-104 T 14-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 A4R43_32815 9686af0f37e94b44419311ee082163af 306 SUPERFAMILY SSF51730 37 301 3.33E-70 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 SUPERFAMILY SSF51735 202 402 3.46E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 SUPERFAMILY SSF51735 9 196 7.09E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 Pfam PF08659 KR domain 206 371 7.2E-35 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 Gene3D G3DSA:3.40.366.10 426 557 4.1E-29 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 206 377 1.0E-22 T 14-10-2018 A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 Pfam PF00698 Acyl transferase domain 428 535 2.2E-20 T 14-10-2018 IPR014043 Acyl transferase A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 390 578 3.4E-11 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 SUPERFAMILY SSF52151 390 482 6.28E-15 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 Gene3D G3DSA:3.40.50.720 2 380 3.0E-90 T 14-10-2018 A4R43_32270 496fa0e8981846d719987cb8aea3794b 581 SUPERFAMILY SSF55048 477 537 1.44E-8 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Gene3D G3DSA:3.90.930.1 573 709 5.8E-16 T 14-10-2018 A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Gene3D G3DSA:3.90.930.1 757 899 4.1E-10 T 14-10-2018 A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 SUPERFAMILY SSF140453 88 163 1.44E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Gene3D G3DSA:2.180.10.10 1072 1349 5.1E-33 T 14-10-2018 A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1276 1349 2.8E-20 T 14-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 603 643 1.2E-12 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 729 763 2.6E-7 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 773 806 0.0026 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 623 660 1.6E-9 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 753 789 1.8E-6 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 665 702 1.9E-6 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 686 727 3.8E-8 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 517 552 1.9E-8 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 581 622 1.9E-6 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 997 1029 1.4E-4 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1153 1184 1.6E-6 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 833 874 5.6E-8 T 14-10-2018 IPR006530 YD repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 666 702 2.0E-7 T 14-10-2018 IPR031325 RHS repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 1153 1182 4.3E-5 T 14-10-2018 IPR031325 RHS repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 686 723 1.1E-7 T 14-10-2018 IPR031325 RHS repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 623 659 2.2E-11 T 14-10-2018 IPR031325 RHS repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 581 618 1.2E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 538 565 1.4E-4 T 14-10-2018 IPR031325 RHS repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 833 869 2.8E-8 T 14-10-2018 IPR031325 RHS repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 773 806 1.1E-4 T 14-10-2018 IPR031325 RHS repeat A4R43_39905 f9571e0b1063ac1357c94204acae3be9 1489 Pfam PF05593 RHS Repeat 729 765 3.1E-7 T 14-10-2018 IPR031325 RHS repeat A4R43_01075 051a41f3ce3af0bf0d3db52eec787708 133 Pfam PF12728 Helix-turn-helix domain 11 58 6.7E-7 T 14-10-2018 A4R43_01075 051a41f3ce3af0bf0d3db52eec787708 133 Gene3D G3DSA:1.10.1660.10 6 46 1.3E-5 T 14-10-2018 A4R43_00620 3fcfbbdcb6e5710a92775f2d928f7d67 569 Pfam PF00999 Sodium/hydrogen exchanger family 10 443 3.7E-53 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 251 259 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 SUPERFAMILY SSF52343 94 208 7.99E-23 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 Gene3D G3DSA:2.40.30.10 1 97 2.1E-27 T 14-10-2018 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 72 86 2.0E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 107 126 2.0E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 48 62 2.0E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 36 48 2.0E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 180 188 2.0E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 26 36 2.0E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 SUPERFAMILY SSF63380 3 96 3.94E-27 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 Gene3D G3DSA:3.10.20.30 206 302 5.0E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 222 292 1.3E-10 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 Gene3D G3DSA:3.40.50.80 101 205 9.4E-19 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_07725 1e79b05a7cea6e9e67407f6d79564b86 302 SUPERFAMILY SSF54292 200 300 1.57E-24 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 SUPERFAMILY SSF52210 385 540 9.03E-39 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 SUPERFAMILY SSF51735 257 392 2.15E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05805 38b301984328e7bab9d103c8315868e8 715 Gene3D G3DSA:3.40.50.720 256 383 4.0E-44 T 14-10-2018 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 Gene3D G3DSA:3.30.470.20 27 236 3.5E-78 T 14-10-2018 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 Gene3D G3DSA:3.40.50.261 384 543 1.3E-53 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 Gene3D G3DSA:3.30.1490.20 45 122 3.5E-78 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 Gene3D G3DSA:3.40.50.261 546 713 8.5E-38 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 SUPERFAMILY SSF56059 31 238 4.57E-39 T 14-10-2018 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 Pfam PF13549 ATP-grasp domain 18 237 1.7E-76 T 14-10-2018 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 405 540 2.3E-49 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A4R43_05805 38b301984328e7bab9d103c8315868e8 715 SMART SM00881 261 356 7.6E-31 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 SUPERFAMILY SSF52210 548 704 3.92E-29 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05805 38b301984328e7bab9d103c8315868e8 715 Pfam PF13380 CoA binding domain 267 385 6.6E-23 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 Pfam PF03466 LysR substrate binding domain 101 299 1.4E-23 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 SUPERFAMILY SSF46785 3 84 1.74E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 Gene3D G3DSA:1.10.10.10 1 86 3.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 Gene3D G3DSA:3.40.190.290 100 315 3.1E-29 T 14-10-2018 A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.9E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11735 5b0a5fb46beef01af45761517a49ef79 329 SUPERFAMILY SSF53850 101 304 5.12E-23 T 14-10-2018 A4R43_18195 92f93e8db41eba2d7223d30e8716d8c8 326 Gene3D G3DSA:3.40.630.30 2 323 7.7E-66 T 14-10-2018 A4R43_18195 92f93e8db41eba2d7223d30e8716d8c8 326 SUPERFAMILY SSF55729 8 317 1.45E-37 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_18195 92f93e8db41eba2d7223d30e8716d8c8 326 Pfam PF00583 Acetyltransferase (GNAT) family 217 308 1.1E-9 T 14-10-2018 IPR000182 GNAT domain A4R43_25800 2dd71ef6aa11db5caf63a21bd7d2d861 345 Pfam PF08279 HTH domain 7 62 1.5E-14 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_25800 2dd71ef6aa11db5caf63a21bd7d2d861 345 Gene3D G3DSA:1.10.10.10 1 65 3.5E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25800 2dd71ef6aa11db5caf63a21bd7d2d861 345 SUPERFAMILY SSF46785 5 62 2.43E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_25800 2dd71ef6aa11db5caf63a21bd7d2d861 345 Pfam PF13280 WYL domain 146 323 5.3E-17 T 14-10-2018 IPR026881 WYL domain A4R43_25800 2dd71ef6aa11db5caf63a21bd7d2d861 345 SMART SM00420 7 63 2.8E-4 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_25800 2dd71ef6aa11db5caf63a21bd7d2d861 345 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_31070 660f401deb8c405acd0987ee8d8bcea0 402 Gene3D G3DSA:3.40.630.30 133 293 9.3E-37 T 14-10-2018 A4R43_31070 660f401deb8c405acd0987ee8d8bcea0 402 Hamap MF_01812 N-acetyltransferase Eis [eis]. 3 402 31.255 T 14-10-2018 IPR022902 N-acetyltransferase Eis A4R43_31070 660f401deb8c405acd0987ee8d8bcea0 402 SUPERFAMILY SSF55729 7 299 3.74E-53 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_31070 660f401deb8c405acd0987ee8d8bcea0 402 SUPERFAMILY SSF55718 301 402 9.81E-22 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_31070 660f401deb8c405acd0987ee8d8bcea0 402 Pfam PF13527 Acetyltransferase (GNAT) domain 6 130 1.4E-25 T 14-10-2018 A4R43_31070 660f401deb8c405acd0987ee8d8bcea0 402 Gene3D G3DSA:3.40.630.30 1 132 2.9E-28 T 14-10-2018 A4R43_31070 660f401deb8c405acd0987ee8d8bcea0 402 Pfam PF13530 Sterol carrier protein domain 177 398 3.0E-55 T 14-10-2018 IPR025559 Enhanced intracellular survival protein domain A4R43_31070 660f401deb8c405acd0987ee8d8bcea0 402 Gene3D G3DSA:3.30.1050.10 299 392 4.5E-24 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_33850 1278d200f3575e90671b7df5ab11dd83 103 Gene3D G3DSA:3.30.70.330 9 100 8.3E-31 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A4R43_33850 1278d200f3575e90671b7df5ab11dd83 103 ProSitePatterns PS00050 Ribosomal protein L23 signature. 82 97 - T 14-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33850 1278d200f3575e90671b7df5ab11dd83 103 SUPERFAMILY SSF54189 8 96 1.4E-31 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33850 1278d200f3575e90671b7df5ab11dd83 103 Pfam PF00276 Ribosomal protein L23 11 93 1.8E-31 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A4R43_33850 1278d200f3575e90671b7df5ab11dd83 103 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 10 100 21.402 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 Gene3D G3DSA:3.40.50.720 3 276 2.8E-64 T 14-10-2018 A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 Pfam PF00106 short chain dehydrogenase 7 185 7.0E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 190 0.0012 T 14-10-2018 A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 SUPERFAMILY SSF51735 4 248 5.14E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15655 d444bde1d4dd531d5a1eb34225cb6980 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11190 dcd620694e270bfe6af5e61b473e5f9c 192 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 7 183 7.1E-44 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_11190 dcd620694e270bfe6af5e61b473e5f9c 192 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 127 2.6E-16 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_11190 dcd620694e270bfe6af5e61b473e5f9c 192 SUPERFAMILY SSF109854 2 133 4.81E-24 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_11190 dcd620694e270bfe6af5e61b473e5f9c 192 Gene3D G3DSA:1.20.120.450 2 131 3.7E-15 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_11190 dcd620694e270bfe6af5e61b473e5f9c 192 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 182 8.3E-27 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_16210 d0302013498b34a11e0b6abc2d9bf76d 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.1E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16210 d0302013498b34a11e0b6abc2d9bf76d 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 9.1E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16210 d0302013498b34a11e0b6abc2d9bf76d 178 Gene3D G3DSA:1.10.357.10 1 178 5.3E-44 T 14-10-2018 A4R43_16210 d0302013498b34a11e0b6abc2d9bf76d 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 6.2E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16210 d0302013498b34a11e0b6abc2d9bf76d 178 SUPERFAMILY SSF46689 1 72 2.24E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 SUPERFAMILY SSF100920 493 585 8.37E-8 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 Pfam PF00012 Hsp70 protein 8 367 9.3E-69 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 Gene3D G3DSA:3.90.640.10 206 293 9.0E-97 T 14-10-2018 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 Gene3D G3DSA:3.30.420.40 167 354 9.0E-97 T 14-10-2018 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 SUPERFAMILY SSF53067 170 367 2.79E-38 T 14-10-2018 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 SUPERFAMILY SSF53067 8 162 4.53E-33 T 14-10-2018 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 PRINTS PR00301 70kDa heat shock protein signature 6 19 3.2E-15 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 PRINTS PR00301 70kDa heat shock protein signature 318 334 3.2E-15 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 PRINTS PR00301 70kDa heat shock protein signature 120 140 3.2E-15 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 PRINTS PR00301 70kDa heat shock protein signature 352 372 3.2E-15 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 PRINTS PR00301 70kDa heat shock protein signature 180 190 3.2E-15 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 10 17 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 Gene3D G3DSA:3.30.420.40 9 363 9.0E-97 T 14-10-2018 A4R43_02595 a7b212e88b52aff54f4121772e56820a 843 Gene3D G3DSA:2.60.34.10 492 631 5.3E-10 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 Gene3D G3DSA:3.50.50.60 31 393 2.7E-129 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 374 386 1.9E-32 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 30 42 1.9E-32 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 105 117 1.9E-32 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 59 71 1.9E-32 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 43 53 1.9E-32 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 344 350 1.9E-32 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 Pfam PF01266 FAD dependent oxidoreductase 31 354 1.6E-51 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 407 531 5.9E-34 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 Gene3D G3DSA:1.10.8.870 418 563 2.5E-32 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 Gene3D G3DSA:3.30.9.10 109 351 2.7E-129 T 14-10-2018 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 379 389 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 SUPERFAMILY SSF51905 28 323 3.79E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35020 923bc581a249bd39e87ef7c7ec947ec9 577 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 35 52 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 5.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 5.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 5.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 SUPERFAMILY SSF46894 140 213 3.13E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 3.8E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 SUPERFAMILY SSF52172 2 137 9.39E-35 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 SMART SM00448 2 117 2.4E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 SMART SM00421 150 207 3.9E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 Pfam PF00072 Response regulator receiver domain 4 117 1.3E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_09815 a1d4a3f9b2ded4774faa9fdc49606184 217 Gene3D G3DSA:3.40.50.12740 2 213 2.3E-68 T 14-10-2018 A4R43_08760 f239ffd2f6122d0794234ce7165bf13e 401 Gene3D G3DSA:1.10.10.10 113 161 1.8E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08760 f239ffd2f6122d0794234ce7165bf13e 401 Gene3D G3DSA:1.25.40.10 301 401 1.4E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08760 f239ffd2f6122d0794234ce7165bf13e 401 Pfam PF04542 Sigma-70 region 2 9 74 9.8E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08760 f239ffd2f6122d0794234ce7165bf13e 401 SUPERFAMILY SSF88946 5 93 3.49E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08760 f239ffd2f6122d0794234ce7165bf13e 401 Gene3D G3DSA:1.10.1740.10 2 71 7.7E-8 T 14-10-2018 A4R43_08760 f239ffd2f6122d0794234ce7165bf13e 401 Pfam PF08281 Sigma-70, region 4 106 156 3.7E-6 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_08760 f239ffd2f6122d0794234ce7165bf13e 401 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 160 3.7E-15 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_08760 f239ffd2f6122d0794234ce7165bf13e 401 SUPERFAMILY SSF88659 99 159 5.05E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_15840 a8e866312b2e99e14775d2a83d6d31da 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 1.9E-50 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A4R43_15840 a8e866312b2e99e14775d2a83d6d31da 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 141 2.7E-41 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A4R43_15840 a8e866312b2e99e14775d2a83d6d31da 141 SUPERFAMILY SSF69500 1 140 1.7E-45 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A4R43_15840 a8e866312b2e99e14775d2a83d6d31da 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 30.191 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A4R43_15840 a8e866312b2e99e14775d2a83d6d31da 141 Gene3D G3DSA:3.50.80.10 1 141 5.9E-45 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A4R43_05505 08d0e3eb0e765614a736b28c005a8154 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 502 8.1E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_05505 08d0e3eb0e765614a736b28c005a8154 513 SUPERFAMILY SSF56801 5 511 5.89E-127 T 14-10-2018 A4R43_05505 08d0e3eb0e765614a736b28c005a8154 513 Gene3D G3DSA:3.40.50.12780 1 411 2.0E-97 T 14-10-2018 A4R43_05505 08d0e3eb0e765614a736b28c005a8154 513 Pfam PF00501 AMP-binding enzyme 11 418 5.5E-81 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_05505 08d0e3eb0e765614a736b28c005a8154 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_05505 08d0e3eb0e765614a736b28c005a8154 513 Gene3D G3DSA:3.30.300.310 414 513 3.9E-23 T 14-10-2018 A4R43_00850 4bc9f6b3efb77003498730a236de12ec 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 61 69 7.5E-5 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_00850 4bc9f6b3efb77003498730a236de12ec 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 87 98 7.5E-5 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_00850 4bc9f6b3efb77003498730a236de12ec 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 129 143 7.5E-5 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_00850 4bc9f6b3efb77003498730a236de12ec 287 Gene3D G3DSA:3.40.50.1820 34 283 7.0E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00850 4bc9f6b3efb77003498730a236de12ec 287 SUPERFAMILY SSF53474 39 278 3.59E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00850 4bc9f6b3efb77003498730a236de12ec 287 Pfam PF12146 Serine aminopeptidase, S33 56 156 1.0E-12 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 A4R43_36585 36b0eff803fe9c4d39cb45eb91186ef8 858 Pfam PF00534 Glycosyl transferases group 1 241 419 2.6E-8 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_36585 36b0eff803fe9c4d39cb45eb91186ef8 858 Pfam PF00535 Glycosyl transferase family 2 451 594 2.3E-23 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_36585 36b0eff803fe9c4d39cb45eb91186ef8 858 SUPERFAMILY SSF53756 135 434 5.08E-24 T 14-10-2018 A4R43_36585 36b0eff803fe9c4d39cb45eb91186ef8 858 Gene3D G3DSA:3.40.50.2000 228 420 4.2E-21 T 14-10-2018 A4R43_36585 36b0eff803fe9c4d39cb45eb91186ef8 858 Gene3D G3DSA:3.90.550.10 445 681 5.2E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_36585 36b0eff803fe9c4d39cb45eb91186ef8 858 SUPERFAMILY SSF53448 443 675 5.44E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 7.1E-14 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 7.1E-14 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 7.1E-14 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 1.2E-9 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.2E-9 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 185 2.9E-64 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 Pfam PF00117 Glutamine amidotransferase class-I 5 185 2.3E-54 T 14-10-2018 IPR017926 Glutamine amidotransferase A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.3E-35 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.3E-35 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.3E-35 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00097 Anthranilate synthase component II signature 46 55 2.3E-35 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.3E-35 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.3E-35 T 14-10-2018 A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 SUPERFAMILY SSF52317 1 186 7.99E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_29125 3edd7f64d0fd1b7ea986b95ba713b1a4 213 Gene3D G3DSA:3.40.50.880 1 192 1.5E-61 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_04445 60ef37b42592bbf6b617086d4b4ddbd8 318 SUPERFAMILY SSF51569 18 309 6.8E-46 T 14-10-2018 A4R43_04445 60ef37b42592bbf6b617086d4b4ddbd8 318 Pfam PF00701 Dihydrodipicolinate synthetase family 19 305 3.2E-16 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_04445 60ef37b42592bbf6b617086d4b4ddbd8 318 SMART SM01130 17 311 2.8E-26 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_04445 60ef37b42592bbf6b617086d4b4ddbd8 318 PIRSF PIRSF001365 15 316 2.9E-37 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_04445 60ef37b42592bbf6b617086d4b4ddbd8 318 Gene3D G3DSA:3.20.20.70 13 314 3.7E-62 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 89 159 1.3E-12 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 Pfam PF03449 Transcription elongation factor, N-terminal 11 79 1.2E-23 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 SUPERFAMILY SSF54534 85 159 1.08E-11 T 14-10-2018 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 8 161 26.515 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 SUPERFAMILY SSF46557 10 81 9.81E-22 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 125 141 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 Gene3D G3DSA:3.10.50.30 85 164 1.0E-10 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 23 53 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 Gene3D G3DSA:1.10.287.180 8 79 3.8E-22 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 A4R43_23685 84fbb10f7e1ffae2de6985c4ebc1a3b3 165 PIRSF PIRSF006092 4 163 4.3E-31 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 852 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 SMART SM00382 199 345 4.4E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 SMART SM00382 601 750 1.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 761 3.2E-53 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 SMART SM01086 768 861 5.8E-35 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 6.4E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 6.4E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 6.4E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 6.4E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Gene3D G3DSA:3.40.50.300 554 766 3.6E-85 T 14-10-2018 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Gene3D G3DSA:3.40.50.300 159 349 1.4E-70 T 14-10-2018 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Gene3D G3DSA:3.40.50.300 350 548 9.0E-73 T 14-10-2018 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Gene3D G3DSA:1.10.1780.10 5 153 1.9E-29 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 SUPERFAMILY SSF52540 158 549 3.25E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 3.8E-26 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Gene3D G3DSA:1.10.8.60 768 863 5.1E-28 T 14-10-2018 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 336 1.2E-11 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 SUPERFAMILY SSF52540 550 850 2.93E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 SUPERFAMILY SSF81923 7 157 1.57E-32 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 9.9E-14 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_31430 846d7bfc67794ec1aba7aa4191a84b3a 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 65 3.7E-9 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_15975 9e75de72b023ff3bba65891fb58883c2 185 SUPERFAMILY SSF51161 3 184 2.36E-49 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_15975 9e75de72b023ff3bba65891fb58883c2 185 SMART SM01266 5 59 1.6E-24 T 14-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 A4R43_15975 9e75de72b023ff3bba65891fb58883c2 185 Gene3D G3DSA:2.160.10.10 2 185 2.8E-64 T 14-10-2018 A4R43_15975 9e75de72b023ff3bba65891fb58883c2 185 Pfam PF12464 Maltose acetyltransferase 7 58 5.7E-19 T 14-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 A4R43_15975 9e75de72b023ff3bba65891fb58883c2 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 166 1.5E-8 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_40945 ebece313b72b3e44034aaedffe477f44 244 Gene3D G3DSA:1.10.357.10 83 236 1.9E-29 T 14-10-2018 A4R43_40945 ebece313b72b3e44034aaedffe477f44 244 Gene3D G3DSA:1.10.10.60 5 81 1.6E-25 T 14-10-2018 A4R43_40945 ebece313b72b3e44034aaedffe477f44 244 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 76 4.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40945 ebece313b72b3e44034aaedffe477f44 244 SUPERFAMILY SSF46689 21 82 5.64E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_40945 ebece313b72b3e44034aaedffe477f44 244 SUPERFAMILY SSF48498 92 236 1.33E-18 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_40945 ebece313b72b3e44034aaedffe477f44 244 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 87 233 6.2E-12 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_24920 2c77afeabae788387b3fe4b6d74f2046 246 Gene3D G3DSA:1.10.10.2600 76 221 3.3E-7 T 14-10-2018 IPR038109 DNA-binding recombinase domain superfamily A4R43_24920 2c77afeabae788387b3fe4b6d74f2046 246 Pfam PF07508 Recombinase 117 220 1.9E-14 T 14-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A4R43_13215 e398d737b3bcb6a4db9a5c9e1375ed5e 141 Pfam PF03259 Roadblock/LC7 domain 12 102 8.6E-22 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_13215 e398d737b3bcb6a4db9a5c9e1375ed5e 141 SUPERFAMILY SSF103196 6 131 1.74E-33 T 14-10-2018 A4R43_13215 e398d737b3bcb6a4db9a5c9e1375ed5e 141 SMART SM00960 12 102 2.1E-27 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_13215 e398d737b3bcb6a4db9a5c9e1375ed5e 141 Gene3D G3DSA:3.30.450.30 8 134 5.3E-41 T 14-10-2018 A4R43_31190 c6a04333fb94d87c4a843c5adcab3045 586 SUPERFAMILY SSF101898 156 449 3.66E-25 T 14-10-2018 A4R43_31190 c6a04333fb94d87c4a843c5adcab3045 586 Pfam PF01436 NHL repeat 165 190 5.3E-5 T 14-10-2018 IPR001258 NHL repeat GO:0005515 A4R43_31190 c6a04333fb94d87c4a843c5adcab3045 586 Pfam PF00578 AhpC/TSA family 3 122 2.4E-10 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_31190 c6a04333fb94d87c4a843c5adcab3045 586 Gene3D G3DSA:2.120.10.30 285 413 2.3E-20 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_31190 c6a04333fb94d87c4a843c5adcab3045 586 SUPERFAMILY SSF52833 11 143 5.49E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_31190 c6a04333fb94d87c4a843c5adcab3045 586 Gene3D G3DSA:3.40.30.10 1 150 1.2E-33 T 14-10-2018 A4R43_31190 c6a04333fb94d87c4a843c5adcab3045 586 Gene3D G3DSA:2.120.10.30 157 260 2.2E-5 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 257 265 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 PRINTS PR00409 Phthalate dioxygenase reductase family signature 71 85 1.8E-31 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 PRINTS PR00409 Phthalate dioxygenase reductase family signature 106 125 1.8E-31 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 PRINTS PR00409 Phthalate dioxygenase reductase family signature 181 189 1.8E-31 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 PRINTS PR00409 Phthalate dioxygenase reductase family signature 131 140 1.8E-31 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 PRINTS PR00409 Phthalate dioxygenase reductase family signature 25 35 1.8E-31 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 PRINTS PR00409 Phthalate dioxygenase reductase family signature 35 47 1.8E-31 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 PRINTS PR00409 Phthalate dioxygenase reductase family signature 47 61 1.8E-31 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 Pfam PF00970 Oxidoreductase FAD-binding domain 23 98 1.5E-6 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 SUPERFAMILY SSF54292 201 306 1.7E-24 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 Gene3D G3DSA:2.40.30.10 1 96 1.5E-29 T 14-10-2018 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 Pfam PF00175 Oxidoreductase NAD-binding domain 107 153 1.4E-4 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 SUPERFAMILY SSF52343 93 215 1.57E-26 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 Gene3D G3DSA:3.40.50.80 99 211 2.1E-23 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 231 299 6.2E-10 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 SUPERFAMILY SSF63380 2 95 2.15E-28 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_07840 b9a08d6df30339e19d9ab1846123b5ad 310 Gene3D G3DSA:3.10.20.30 214 307 2.5E-21 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_15900 25f5bca93f8b150e2f8d37337fdbcd4c 511 Gene3D G3DSA:3.40.50.12780 5 398 1.4E-100 T 14-10-2018 A4R43_15900 25f5bca93f8b150e2f8d37337fdbcd4c 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 493 2.5E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_15900 25f5bca93f8b150e2f8d37337fdbcd4c 511 Gene3D G3DSA:3.30.300.310 402 506 4.0E-31 T 14-10-2018 A4R43_15900 25f5bca93f8b150e2f8d37337fdbcd4c 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_15900 25f5bca93f8b150e2f8d37337fdbcd4c 511 Pfam PF00501 AMP-binding enzyme 8 406 1.7E-76 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_15900 25f5bca93f8b150e2f8d37337fdbcd4c 511 SUPERFAMILY SSF56801 6 506 8.37E-128 T 14-10-2018 A4R43_26145 9cafdf4fb402ae12b3582f20e530c1a8 273 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 8 266 1.6E-85 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4R43_26145 9cafdf4fb402ae12b3582f20e530c1a8 273 SUPERFAMILY SSF53613 5 269 4.68E-73 T 14-10-2018 IPR029056 Ribokinase-like A4R43_26145 9cafdf4fb402ae12b3582f20e530c1a8 273 Pfam PF08543 Phosphomethylpyrimidine kinase 15 264 2.6E-87 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A4R43_26145 9cafdf4fb402ae12b3582f20e530c1a8 273 Gene3D G3DSA:3.40.1190.20 1 273 3.7E-93 T 14-10-2018 IPR029056 Ribokinase-like A4R43_38195 3d8d94611bf619969cea326a424a9be8 141 Gene3D G3DSA:1.10.10.10 10 70 1.5E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38195 3d8d94611bf619969cea326a424a9be8 141 SUPERFAMILY SSF52172 2 61 6.46E-8 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_38195 3d8d94611bf619969cea326a424a9be8 141 SMART SM01012 7 62 4.4E-20 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_38195 3d8d94611bf619969cea326a424a9be8 141 Pfam PF03861 ANTAR domain 11 61 6.2E-19 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_06755 ac9d4b7994b467673545d3356e700eb6 613 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 441 587 1.1E-18 T 14-10-2018 A4R43_06755 ac9d4b7994b467673545d3356e700eb6 613 Gene3D G3DSA:2.60.120.200 396 590 1.2E-21 T 14-10-2018 A4R43_06755 ac9d4b7994b467673545d3356e700eb6 613 SUPERFAMILY SSF49899 391 589 3.08E-22 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_06755 ac9d4b7994b467673545d3356e700eb6 613 Pfam PF13088 BNR repeat-like domain 54 362 6.3E-34 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_06755 ac9d4b7994b467673545d3356e700eb6 613 Gene3D G3DSA:2.120.10.10 22 395 1.0E-102 T 14-10-2018 A4R43_06755 ac9d4b7994b467673545d3356e700eb6 613 SUPERFAMILY SSF50939 29 394 3.08E-87 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_06755 ac9d4b7994b467673545d3356e700eb6 613 SMART SM00560 450 585 7.8E-4 T 14-10-2018 IPR006558 LamG-like jellyroll fold A4R43_22035 5325fb2e3a985cdc89b9549b66889cc1 376 Gene3D G3DSA:2.30.42.10 141 235 2.8E-12 T 14-10-2018 A4R43_22035 5325fb2e3a985cdc89b9549b66889cc1 376 SUPERFAMILY SSF54211 260 364 1.67E-22 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_22035 5325fb2e3a985cdc89b9549b66889cc1 376 SUPERFAMILY SSF50156 169 273 1.45E-14 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 A4R43_22035 5325fb2e3a985cdc89b9549b66889cc1 376 Pfam PF13180 PDZ domain 170 230 4.3E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_22035 5325fb2e3a985cdc89b9549b66889cc1 376 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 272 360 5.1E-14 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A4R43_22035 5325fb2e3a985cdc89b9549b66889cc1 376 SMART SM00228 113 226 2.3E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_22035 5325fb2e3a985cdc89b9549b66889cc1 376 Gene3D G3DSA:3.30.230.10 236 371 1.8E-21 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_00525 1e7133bed45c6d7f94d5c0f6b6e2171a 568 SUPERFAMILY SSF52540 322 562 1.54E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_00525 1e7133bed45c6d7f94d5c0f6b6e2171a 568 Pfam PF00664 ABC transporter transmembrane region 41 280 1.1E-16 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_00525 1e7133bed45c6d7f94d5c0f6b6e2171a 568 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_00525 1e7133bed45c6d7f94d5c0f6b6e2171a 568 Gene3D G3DSA:3.40.50.300 326 566 2.0E-85 T 14-10-2018 A4R43_00525 1e7133bed45c6d7f94d5c0f6b6e2171a 568 Pfam PF00005 ABC transporter 346 494 2.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_00525 1e7133bed45c6d7f94d5c0f6b6e2171a 568 SUPERFAMILY SSF90123 5 322 3.79E-47 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_00525 1e7133bed45c6d7f94d5c0f6b6e2171a 568 Gene3D G3DSA:1.20.1560.10 3 317 4.2E-39 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_00525 1e7133bed45c6d7f94d5c0f6b6e2171a 568 SMART SM00382 354 540 6.5E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_16285 703022582df7d36806181e054eaeee63 287 SUPERFAMILY SSF47413 11 66 6.19E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_16285 703022582df7d36806181e054eaeee63 287 Gene3D G3DSA:1.10.260.40 5 84 1.3E-8 T 14-10-2018 A4R43_16285 703022582df7d36806181e054eaeee63 287 SMART SM00530 17 72 3.7E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_16285 703022582df7d36806181e054eaeee63 287 Pfam PF13560 Helix-turn-helix domain 13 75 9.7E-17 T 14-10-2018 A4R43_27915 c3bb75830b4704ad8b2ac24894fc62b1 499 Gene3D G3DSA:3.30.70.1230 313 499 1.0E-47 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_27915 c3bb75830b4704ad8b2ac24894fc62b1 499 SMART SM00044 290 479 1.9E-11 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4R43_27915 c3bb75830b4704ad8b2ac24894fc62b1 499 SUPERFAMILY SSF55073 318 497 5.18E-46 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_27915 c3bb75830b4704ad8b2ac24894fc62b1 499 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 322 495 9.2E-26 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4R43_27915 c3bb75830b4704ad8b2ac24894fc62b1 499 SMART SM00304 242 294 1.5E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_27915 c3bb75830b4704ad8b2ac24894fc62b1 499 Pfam PF00672 HAMP domain 242 291 2.8E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_27915 c3bb75830b4704ad8b2ac24894fc62b1 499 Gene3D G3DSA:1.20.1480.50 219 298 2.9E-10 T 14-10-2018 A4R43_27915 c3bb75830b4704ad8b2ac24894fc62b1 499 SUPERFAMILY SSF158472 242 291 3.53E-9 T 14-10-2018 A4R43_16820 742f44e1632a05abfae8785550c35658 228 Gene3D G3DSA:1.10.10.10 24 89 3.4E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_16820 742f44e1632a05abfae8785550c35658 228 Pfam PF00717 Peptidase S24-like 148 212 5.5E-14 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A4R43_16820 742f44e1632a05abfae8785550c35658 228 Pfam PF01726 LexA DNA binding domain 23 86 1.0E-25 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 A4R43_16820 742f44e1632a05abfae8785550c35658 228 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 183 195 6.1E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4R43_16820 742f44e1632a05abfae8785550c35658 228 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 155 166 6.1E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4R43_16820 742f44e1632a05abfae8785550c35658 228 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 144 154 6.1E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4R43_16820 742f44e1632a05abfae8785550c35658 228 SUPERFAMILY SSF51306 108 226 1.29E-34 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4R43_16820 742f44e1632a05abfae8785550c35658 228 SUPERFAMILY SSF46785 24 90 1.09E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_16820 742f44e1632a05abfae8785550c35658 228 Gene3D G3DSA:2.10.109.10 113 228 3.6E-40 T 14-10-2018 A4R43_16820 742f44e1632a05abfae8785550c35658 228 TIGRFAM TIGR00498 lexA: repressor LexA 23 227 4.4E-75 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A4R43_16820 742f44e1632a05abfae8785550c35658 228 Hamap MF_00015 LexA repressor [lexA]. 24 228 32.449 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF52777 2987 3146 2.0E-27 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF56801 217 787 3.92E-135 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SMART SM01294 1850 1916 1.9E-4 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:1.10.1200.10 1837 1922 9.8E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF56801 1294 1862 1.7E-143 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.559.30 1044 1309 9.1E-91 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00668 Condensation domain 1933 2369 6.0E-83 T 14-10-2018 IPR001242 Condensation domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00668 Condensation domain 2984 3391 2.0E-53 T 14-10-2018 IPR001242 Condensation domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00668 Condensation domain 870 1309 1.8E-83 T 14-10-2018 IPR001242 Condensation domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.559.10 1936 2296 1.8E-112 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00975 Thioesterase domain 3413 3534 1.1E-22 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.559.30 3137 3392 9.5E-42 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF47336 1841 1916 1.31E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00501 AMP-binding enzyme 2387 2784 4.0E-86 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00501 AMP-binding enzyme 257 667 8.0E-88 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00501 AMP-binding enzyme 1334 1741 6.5E-87 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF52777 2115 2351 1.11E-50 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF52777 871 1053 1.89E-31 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.559.30 2110 2348 1.8E-112 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 ProSitePatterns PS00455 Putative AMP-binding domain signature. 406 417 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.559.30 32 242 2.7E-7 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF53474 3399 3620 5.0E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.559.10 2971 3135 1.4E-38 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF47336 769 854 6.15E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF13193 AMP-binding enzyme C-terminal domain 1749 1822 1.4E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF13193 AMP-binding enzyme C-terminal domain 2793 2871 6.2E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF13193 AMP-binding enzyme C-terminal domain 676 751 1.2E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1875 1890 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.40.50.12780 244 662 1.6E-112 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.40.50.12780 2375 2779 1.1E-115 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF52777 3151 3388 8.45E-22 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.40.50.1820 3406 3624 9.5E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF47336 2889 2962 5.76E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:1.10.1200.10 761 852 2.2E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:1.10.1200.10 2886 2966 1.5E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.300.30 2780 2885 6.9E-25 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.40.50.12780 1324 1733 1.9E-121 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SMART SM00823 Phosphopantetheine attachment site 2898 2966 7.0E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SMART SM00823 Phosphopantetheine attachment site 774 845 4.2E-8 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SMART SM00823 Phosphopantetheine attachment site 1849 1920 1.8E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF52777 1045 1303 8.12E-36 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2408 2809 4.8E-126 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1355 1764 1.7E-127 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 278 692 7.2E-118 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2921 2936 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00550 Phosphopantetheine attachment site 776 841 9.3E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00550 Phosphopantetheine attachment site 2899 2960 3.4E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Pfam PF00550 Phosphopantetheine attachment site 1851 1916 3.0E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF56801 2350 2905 1.01E-133 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.300.30 663 760 1.1E-27 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 SUPERFAMILY SSF52777 1938 2106 9.45E-31 T 14-10-2018 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.559.10 871 1245 9.1E-91 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_03220 6650d84afb28c3c7e306a942d7082b45 3630 Gene3D G3DSA:3.30.300.30 1737 1835 1.0E-27 T 14-10-2018 A4R43_40315 5cccde4573e262d849bd0572941ea201 146 SMART SM00347 32 130 5.9E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40315 5cccde4573e262d849bd0572941ea201 146 SUPERFAMILY SSF46785 12 138 4.75E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40315 5cccde4573e262d849bd0572941ea201 146 Pfam PF13463 Winged helix DNA-binding domain 45 104 4.0E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40315 5cccde4573e262d849bd0572941ea201 146 Gene3D G3DSA:1.10.10.10 6 143 6.2E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26620 b727cdb54c113d38854a0861219d70af 137 Gene3D G3DSA:3.40.50.1010 1 133 6.5E-21 T 14-10-2018 A4R43_26620 b727cdb54c113d38854a0861219d70af 137 Pfam PF01850 PIN domain 2 121 4.4E-10 T 14-10-2018 IPR002716 PIN domain A4R43_26620 b727cdb54c113d38854a0861219d70af 137 SUPERFAMILY SSF88723 2 128 5.61E-20 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_26620 b727cdb54c113d38854a0861219d70af 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 131 9.832 T 14-10-2018 IPR022907 VapC family GO:0004540 A4R43_08500 0b3643b68729c262cf302e1dd2ecc5ef 310 SUPERFAMILY SSF46689 204 254 1.75E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08500 0b3643b68729c262cf302e1dd2ecc5ef 310 Gene3D G3DSA:1.10.10.60 204 263 1.6E-12 T 14-10-2018 A4R43_08500 0b3643b68729c262cf302e1dd2ecc5ef 310 Gene3D G3DSA:1.10.10.60 264 307 8.9E-11 T 14-10-2018 A4R43_08500 0b3643b68729c262cf302e1dd2ecc5ef 310 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 258 300 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_08500 0b3643b68729c262cf302e1dd2ecc5ef 310 Pfam PF12833 Helix-turn-helix domain 227 305 9.6E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_08500 0b3643b68729c262cf302e1dd2ecc5ef 310 Pfam PF12852 Cupin 2 189 3.4E-42 T 14-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain A4R43_08500 0b3643b68729c262cf302e1dd2ecc5ef 310 SUPERFAMILY SSF46689 257 305 8.36E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08500 0b3643b68729c262cf302e1dd2ecc5ef 310 SMART SM00342 221 304 2.7E-29 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_27430 25adda3325d0b8ae1a4db6d79067973e 213 Gene3D G3DSA:3.40.630.40 1 212 5.9E-58 T 14-10-2018 A4R43_27430 25adda3325d0b8ae1a4db6d79067973e 213 SMART SM00646 86 208 3.3E-16 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4R43_27430 25adda3325d0b8ae1a4db6d79067973e 213 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 2 208 2.5E-37 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4R43_27430 25adda3325d0b8ae1a4db6d79067973e 213 SUPERFAMILY SSF53187 1 211 2.92E-35 T 14-10-2018 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 Gene3D G3DSA:1.10.580.10 65 420 3.7E-141 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 SUPERFAMILY SSF48256 13 437 1.19E-157 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 PIRSF PIRSF001369 45 437 7.1E-157 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 22 431 1.7E-177 T 14-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 Gene3D G3DSA:2.20.28.60 9 58 1.6E-16 T 14-10-2018 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 PRINTS PR00143 Citrate synthase signature 368 384 5.0E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 PRINTS PR00143 Citrate synthase signature 249 277 5.0E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 PRINTS PR00143 Citrate synthase signature 388 402 5.0E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 PRINTS PR00143 Citrate synthase signature 227 242 5.0E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 PRINTS PR00143 Citrate synthase signature 173 186 5.0E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 PRINTS PR00143 Citrate synthase signature 305 325 5.0E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 Pfam PF00285 Citrate synthase, C-terminal domain 54 420 2.0E-133 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 Gene3D G3DSA:1.10.230.10 276 385 3.7E-141 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain A4R43_25535 1a1f27a2e2f435e0ee4bff9d23d36be6 437 ProSitePatterns PS00480 Citrate synthase signature. 312 324 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4R43_11095 33174ef5db2c4b20c1301370124eff24 178 Pfam PF12804 MobA-like NTP transferase domain 4 151 3.1E-24 T 14-10-2018 IPR025877 MobA-like NTP transferase A4R43_11095 33174ef5db2c4b20c1301370124eff24 178 Gene3D G3DSA:3.90.550.10 2 178 3.6E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_11095 33174ef5db2c4b20c1301370124eff24 178 SUPERFAMILY SSF53448 2 174 2.18E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 SUPERFAMILY SSF48557 13 465 3.3E-131 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 Pfam PF14698 Argininosuccinate lyase C-terminal 371 439 7.5E-23 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 8.5E-55 T 14-10-2018 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 8.5E-55 T 14-10-2018 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 8.5E-55 T 14-10-2018 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 8.5E-55 T 14-10-2018 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00145 Argininosuccinate lyase family signature 318 337 8.5E-55 T 14-10-2018 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 8.5E-55 T 14-10-2018 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 461 39.16 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 Pfam PF00206 Lyase 20 308 7.7E-65 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 Gene3D G3DSA:1.10.40.30 368 440 3.2E-164 T 14-10-2018 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 1.5E-27 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 1.5E-27 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 1.5E-27 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 1.5E-27 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 Gene3D G3DSA:1.10.275.10 32 237 3.2E-164 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 456 2.9E-177 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4R43_14300 ea6a273e539b2d8a03b3e931d9adb2ae 471 Gene3D G3DSA:1.20.200.10 127 455 3.2E-164 T 14-10-2018 A4R43_11215 694cd773ca45dae52fcaef476b9a9e17 242 SUPERFAMILY SSF51430 5 239 6.29E-41 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_11215 694cd773ca45dae52fcaef476b9a9e17 242 Gene3D G3DSA:3.20.20.100 1 242 1.4E-47 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_11215 694cd773ca45dae52fcaef476b9a9e17 242 PRINTS PR00069 Aldo-keto reductase signature 175 199 9.6E-6 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_11215 694cd773ca45dae52fcaef476b9a9e17 242 PRINTS PR00069 Aldo-keto reductase signature 81 99 9.6E-6 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_11215 694cd773ca45dae52fcaef476b9a9e17 242 Pfam PF00248 Aldo/keto reductase family 79 239 5.7E-13 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 SUPERFAMILY SSF51905 4 393 1.43E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 Gene3D G3DSA:3.50.50.60 1 167 1.5E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 9.2E-8 T 14-10-2018 A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 130 139 9.2E-8 T 14-10-2018 A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 9.2E-8 T 14-10-2018 A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 3.0E-6 T 14-10-2018 A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.0E-6 T 14-10-2018 A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 3.0E-6 T 14-10-2018 A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 Gene3D G3DSA:3.50.50.60 302 477 1.1E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_36555 caf3672457fee5eb2cba761154d419a6 501 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 206 1.3E-17 T 14-10-2018 A4R43_02025 c2aeda23a1407baad5291eb98c1f5c37 377 Gene3D G3DSA:1.20.1250.20 1 375 3.3E-39 T 14-10-2018 A4R43_02025 c2aeda23a1407baad5291eb98c1f5c37 377 Pfam PF07690 Major Facilitator Superfamily 3 280 1.9E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_02025 c2aeda23a1407baad5291eb98c1f5c37 377 PRINTS PR01035 Tetracycline resistance protein signature 118 140 1.5E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_02025 c2aeda23a1407baad5291eb98c1f5c37 377 PRINTS PR01035 Tetracycline resistance protein signature 28 47 1.5E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_02025 c2aeda23a1407baad5291eb98c1f5c37 377 PRINTS PR01035 Tetracycline resistance protein signature 351 370 1.5E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_02025 c2aeda23a1407baad5291eb98c1f5c37 377 SUPERFAMILY SSF103473 7 370 7.32E-44 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 SUPERFAMILY SSF54849 136 204 1.79E-19 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 Gene3D G3DSA:3.50.7.10 190 370 2.0E-211 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 9.0E-86 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 PRINTS PR00298 60kDa chaperonin signature 82 109 1.4E-66 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 PRINTS PR00298 60kDa chaperonin signature 266 289 1.4E-66 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 PRINTS PR00298 60kDa chaperonin signature 396 417 1.4E-66 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 PRINTS PR00298 60kDa chaperonin signature 348 373 1.4E-66 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 PRINTS PR00298 60kDa chaperonin signature 26 52 1.4E-66 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 Gene3D G3DSA:3.30.260.10 135 408 2.0E-211 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 8.8E-227 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 SUPERFAMILY SSF48592 1 523 9.07E-74 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 SUPERFAMILY SSF52029 183 374 5.06E-73 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 Hamap MF_00600 60 kDa chaperonin [groL]. 1 536 38.699 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 Gene3D G3DSA:1.10.560.10 7 518 2.0E-211 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily A4R43_34295 5f21acb77f9b0013909b3df86272b6b3 538 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_32395 80f71aff7c69c323374e38c7925f2991 571 Gene3D G3DSA:3.40.50.300 324 569 2.5E-60 T 14-10-2018 A4R43_32395 80f71aff7c69c323374e38c7925f2991 571 SMART SM00382 357 540 1.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_32395 80f71aff7c69c323374e38c7925f2991 571 Gene3D G3DSA:1.20.1560.10 2 319 1.0E-15 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_32395 80f71aff7c69c323374e38c7925f2991 571 SUPERFAMILY SSF52540 326 561 2.57E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_32395 80f71aff7c69c323374e38c7925f2991 571 Pfam PF00005 ABC transporter 350 496 2.9E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_32395 80f71aff7c69c323374e38c7925f2991 571 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_32395 80f71aff7c69c323374e38c7925f2991 571 SUPERFAMILY SSF90123 8 316 1.57E-26 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_26005 754a795291d8929fa942de7b64668911 222 SUPERFAMILY SSF110395 4 219 1.7E-43 T 14-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 A4R43_26005 754a795291d8929fa942de7b64668911 222 Pfam PF03932 CutC family 5 196 9.3E-36 T 14-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A4R43_26005 754a795291d8929fa942de7b64668911 222 Gene3D G3DSA:3.20.20.380 3 218 7.1E-52 T 14-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 A4R43_40940 90f1f3db3b7b5206d6243605f7dfcc43 304 SMART SM00382 26 208 2.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_40940 90f1f3db3b7b5206d6243605f7dfcc43 304 Gene3D G3DSA:3.40.50.300 1 237 5.5E-63 T 14-10-2018 A4R43_40940 90f1f3db3b7b5206d6243605f7dfcc43 304 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_40940 90f1f3db3b7b5206d6243605f7dfcc43 304 Pfam PF00005 ABC transporter 17 159 1.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_40940 90f1f3db3b7b5206d6243605f7dfcc43 304 SUPERFAMILY SSF52540 2 221 9.91E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 Pfam PF00155 Aminotransferase class I and II 135 432 1.0E-23 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 SMART SM00345 26 87 3.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 SUPERFAMILY SSF53383 78 446 1.71E-73 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 4.4E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 4.4E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 Gene3D G3DSA:3.90.1150.10 100 443 3.4E-69 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 Gene3D G3DSA:3.40.640.10 134 343 3.4E-69 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 Gene3D G3DSA:1.10.10.10 18 87 5.6E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 80 2.5E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19655 0e808adf875e78ae165239d5f3debaa2 463 SUPERFAMILY SSF46785 19 81 1.48E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26095 43d632ae6e9990a156e21469914065e5 404 SUPERFAMILY SSF63882 5 177 5.63E-52 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_26095 43d632ae6e9990a156e21469914065e5 404 SMART SM00852 182 318 7.4E-35 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_26095 43d632ae6e9990a156e21469914065e5 404 Pfam PF03454 MoeA C-terminal region (domain IV) 331 404 2.7E-14 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_26095 43d632ae6e9990a156e21469914065e5 404 Gene3D G3DSA:3.40.980.10 177 316 5.3E-107 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4R43_26095 43d632ae6e9990a156e21469914065e5 404 Gene3D G3DSA:2.40.340.10 328 401 4.7E-18 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_26095 43d632ae6e9990a156e21469914065e5 404 Pfam PF00994 Probable molybdopterin binding domain 183 316 8.3E-24 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_26095 43d632ae6e9990a156e21469914065e5 404 SUPERFAMILY SSF53218 179 322 1.07E-37 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4R43_26095 43d632ae6e9990a156e21469914065e5 404 Gene3D G3DSA:2.170.190.11 47 143 5.3E-107 T 14-10-2018 A4R43_26095 43d632ae6e9990a156e21469914065e5 404 Gene3D G3DSA:3.90.105.10 25 176 5.3E-107 T 14-10-2018 A4R43_26095 43d632ae6e9990a156e21469914065e5 404 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 179 314 4.0E-30 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_26095 43d632ae6e9990a156e21469914065e5 404 SUPERFAMILY SSF63867 327 404 1.28E-16 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_26095 43d632ae6e9990a156e21469914065e5 404 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 169 3.4E-46 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 SUPERFAMILY SSF56014 417 557 5.76E-38 T 14-10-2018 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 171 323 2.2E-39 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 Gene3D G3DSA:3.30.413.10 418 562 6.3E-42 T 14-10-2018 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 PRINTS PR00397 Sirohaem Fe-binding site signature 468 486 1.0E-9 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 PRINTS PR00397 Sirohaem Fe-binding site signature 421 439 1.0E-9 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 421 555 3.4E-14 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 SUPERFAMILY SSF55124 20 170 2.78E-37 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 344 407 1.8E-11 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 100 161 2.7E-16 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 468 484 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 Gene3D G3DSA:3.30.413.10 163 339 1.8E-122 T 14-10-2018 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 SUPERFAMILY SSF56014 171 329 3.66E-46 T 14-10-2018 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 Gene3D G3DSA:3.90.480.20 33 404 1.8E-122 T 14-10-2018 A4R43_39515 9f86d011c05afdcbd1d8459a66955cf2 562 SUPERFAMILY SSF55124 337 413 5.56E-17 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_15955 3bedb1a84b409a9fa5e947a075fa3fbe 287 Pfam PF01144 Coenzyme A transferase 6 205 3.5E-39 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_15955 3bedb1a84b409a9fa5e947a075fa3fbe 287 SUPERFAMILY SSF100950 3 270 1.73E-71 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_15955 3bedb1a84b409a9fa5e947a075fa3fbe 287 Gene3D G3DSA:3.30.30.40 115 152 1.1E-73 T 14-10-2018 A4R43_15955 3bedb1a84b409a9fa5e947a075fa3fbe 287 SMART SM00882 5 227 4.0E-37 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_15955 3bedb1a84b409a9fa5e947a075fa3fbe 287 Gene3D G3DSA:3.40.1080.10 9 270 1.1E-73 T 14-10-2018 A4R43_36870 f120f603fa12b907659d8a117740df8f 446 Gene3D G3DSA:1.20.1250.20 233 432 8.7E-23 T 14-10-2018 A4R43_36870 f120f603fa12b907659d8a117740df8f 446 Pfam PF07690 Major Facilitator Superfamily 38 349 7.9E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_36870 f120f603fa12b907659d8a117740df8f 446 SUPERFAMILY SSF103473 21 425 7.98E-51 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_36870 f120f603fa12b907659d8a117740df8f 446 Gene3D G3DSA:1.20.1250.20 22 220 2.5E-16 T 14-10-2018 A4R43_39400 d4688a96903f22378a5b30f7957a4f79 129 SUPERFAMILY SSF54593 10 115 1.29E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_39400 d4688a96903f22378a5b30f7957a4f79 129 Gene3D G3DSA:3.10.180.10 6 115 1.8E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_39400 d4688a96903f22378a5b30f7957a4f79 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 108 4.8E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_38225 da4a1492bb5ac0e0068644afd0374d88 96 Pfam PF12079 Protein of unknown function (DUF3558) 26 91 1.8E-9 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Gene3D G3DSA:3.30.70.1430 556 653 4.9E-268 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Gene3D G3DSA:1.20.1640.10 12 500 4.9E-268 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 SUPERFAMILY SSF82866 784 1007 5.1E-48 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Gene3D G3DSA:3.30.70.1440 654 844 4.9E-268 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 SUPERFAMILY SSF82866 286 483 6.28E-42 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 SUPERFAMILY SSF82693 135 314 1.15E-11 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Gene3D G3DSA:3.30.70.1320 132 318 4.9E-268 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Gene3D G3DSA:1.20.1640.10 501 1002 4.9E-268 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 PRINTS PR00702 Acriflavin resistance protein family signature 455 478 1.1E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 PRINTS PR00702 Acriflavin resistance protein family signature 322 345 1.1E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 PRINTS PR00702 Acriflavin resistance protein family signature 430 453 1.1E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.1E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 PRINTS PR00702 Acriflavin resistance protein family signature 349 370 1.1E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 PRINTS PR00702 Acriflavin resistance protein family signature 377 401 1.1E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.1E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 SUPERFAMILY SSF82714 702 784 1.2E-9 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Gene3D G3DSA:3.30.2090.10 701 787 4.9E-268 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 SUPERFAMILY SSF82693 42 126 2.62E-22 T 14-10-2018 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Pfam PF00873 AcrB/AcrD/AcrF family 5 1005 4.2E-210 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Gene3D G3DSA:3.30.2090.10 177 263 4.9E-268 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 SUPERFAMILY SSF82714 182 258 1.31E-7 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4R43_15790 b72dc30404402443db6e5f2fe0667dc5 1029 Gene3D G3DSA:3.30.70.1430 41 795 4.9E-268 T 14-10-2018 A4R43_39025 8afb2e46b1735d7a295da5d26c58a56c 447 Gene3D G3DSA:3.30.43.10 390 446 1.0E-9 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_39025 8afb2e46b1735d7a295da5d26c58a56c 447 Gene3D G3DSA:3.30.465.10 96 222 2.4E-128 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_39025 8afb2e46b1735d7a295da5d26c58a56c 447 SUPERFAMILY SSF56176 21 211 4.44E-48 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_39025 8afb2e46b1735d7a295da5d26c58a56c 447 Pfam PF01565 FAD binding domain 47 181 5.4E-31 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_39025 8afb2e46b1735d7a295da5d26c58a56c 447 SUPERFAMILY SSF55103 212 445 1.37E-42 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_39025 8afb2e46b1735d7a295da5d26c58a56c 447 Pfam PF09265 Cytokinin dehydrogenase 1, FAD and cytokinin binding 279 445 3.1E-27 T 14-10-2018 IPR015345 Cytokinin dehydrogenase 1, FAD/cytokinin binding domain GO:0009690|GO:0019139|GO:0050660|GO:0055114 KEGG: 00908+1.5.99.12 A4R43_39025 8afb2e46b1735d7a295da5d26c58a56c 447 Gene3D G3DSA:3.30.43.10 29 95 2.4E-128 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_39025 8afb2e46b1735d7a295da5d26c58a56c 447 Gene3D G3DSA:3.40.462.10 223 389 2.4E-128 T 14-10-2018 IPR016170 Cytokinin dehydrogenase, C-terminal domain superfamily KEGG: 00908+1.5.99.12 A4R43_24955 b875f0a7bbbfc70b251bd1289228cf3a 201 Gene3D G3DSA:3.40.50.10420 9 193 4.8E-35 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily A4R43_24955 b875f0a7bbbfc70b251bd1289228cf3a 201 PIRSF PIRSF006806 8 190 1.2E-32 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4R43_24955 b875f0a7bbbfc70b251bd1289228cf3a 201 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 11 186 6.7E-31 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4R43_24955 b875f0a7bbbfc70b251bd1289228cf3a 201 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 11 185 4.8E-35 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4R43_24955 b875f0a7bbbfc70b251bd1289228cf3a 201 SUPERFAMILY SSF100950 10 190 5.86E-37 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_26165 6afbc125049f9e4db5500d7c824ca7c1 145 SMART SM00347 25 125 1.6E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_26165 6afbc125049f9e4db5500d7c824ca7c1 145 Pfam PF01047 MarR family 37 89 3.9E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_26165 6afbc125049f9e4db5500d7c824ca7c1 145 Gene3D G3DSA:1.10.10.10 8 142 5.9E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26165 6afbc125049f9e4db5500d7c824ca7c1 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_26165 6afbc125049f9e4db5500d7c824ca7c1 145 SUPERFAMILY SSF46785 7 140 2.04E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_37190 ecf1ca6db43b06c3565c74b3823992af 399 Pfam PF01757 Acyltransferase family 1 363 1.2E-24 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 Gene3D G3DSA:2.40.50.100 288 333 1.5E-6 T 14-10-2018 A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 Gene3D G3DSA:2.40.50.140 245 287 1.5E-6 T 14-10-2018 A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 Pfam PF08402 TOBE domain 285 355 1.3E-5 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 Pfam PF00005 ABC transporter 19 167 3.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 Gene3D G3DSA:3.40.50.300 1 244 4.1E-72 T 14-10-2018 A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 SUPERFAMILY SSF52540 4 248 8.49E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 SMART SM00382 28 217 1.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_02050 a5b35600bcda5caa6aea4742b549487f 375 SUPERFAMILY SSF50331 243 337 4.76E-14 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 Gene3D G3DSA:2.60.40.290 328 428 1.0E-27 T 14-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 SUPERFAMILY SSF56112 4 270 5.93E-70 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 Pfam PF00553 Cellulose binding domain 332 418 4.7E-24 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 SUPERFAMILY SSF49384 330 416 1.05E-25 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 SMART SM00637 332 427 5.1E-34 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 SMART SM00220 11 257 2.2E-55 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 PIRSF PIRSF000654 16 257 2.6E-22 T 14-10-2018 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 Gene3D G3DSA:3.30.200.20 1 89 1.8E-26 T 14-10-2018 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 Gene3D G3DSA:1.10.510.10 90 270 6.8E-44 T 14-10-2018 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 125 137 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_13145 5ba95edb21858464eadd381ca43d0874 430 Pfam PF00069 Protein kinase domain 11 253 2.6E-45 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 Gene3D G3DSA:3.40.50.2300 113 249 5.6E-54 T 14-10-2018 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 Gene3D G3DSA:1.10.10.60 931 981 1.4E-11 T 14-10-2018 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 Pfam PF12833 Helix-turn-helix domain 954 1031 8.9E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 985 1027 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 SUPERFAMILY SSF53822 7 290 5.14E-41 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 SUPERFAMILY SSF47384 495 571 1.18E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 SUPERFAMILY SSF55874 598 686 1.02E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 SMART SM00342 948 1031 7.7E-31 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 SUPERFAMILY SSF46689 984 1031 2.96E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 Gene3D G3DSA:3.40.50.2300 803 924 1.1E-5 T 14-10-2018 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 Pfam PF13377 Periplasmic binding protein-like domain 122 288 3.3E-31 T 14-10-2018 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 SMART SM00387 605 689 0.0022 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 Gene3D G3DSA:3.40.50.2300 3 266 5.6E-54 T 14-10-2018 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 SUPERFAMILY SSF52172 804 886 1.08E-7 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 Gene3D G3DSA:3.30.565.10 603 688 1.1E-5 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 Gene3D G3DSA:1.10.10.60 982 1033 1.1E-17 T 14-10-2018 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 1015 1031 5.2E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 1000 1015 5.2E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_00205 81f99c6a5dab8664cb62612f0578b79e 1035 SUPERFAMILY SSF46689 933 982 3.4E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03895 986577524ac58fc7b0510966f258b9ce 231 SUPERFAMILY SSF52540 8 225 2.42E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_03895 986577524ac58fc7b0510966f258b9ce 231 Gene3D G3DSA:3.40.50.300 5 230 3.6E-68 T 14-10-2018 A4R43_03895 986577524ac58fc7b0510966f258b9ce 231 SMART SM00382 36 222 3.2E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03895 986577524ac58fc7b0510966f258b9ce 231 Pfam PF00005 ABC transporter 27 173 9.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 SUPERFAMILY SSF48264 13 394 4.19E-78 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 Pfam PF00067 Cytochrome P450 269 364 8.0E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 93 104 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 140 156 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 268 279 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 157 172 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 285 312 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 334 343 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 343 354 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 195 217 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00359 B-class P450 signature 313 328 3.1E-54 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 Gene3D G3DSA:1.10.630.10 10 396 4.3E-107 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00385 P450 superfamily signature 343 354 1.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00385 P450 superfamily signature 334 343 1.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00385 P450 superfamily signature 236 253 1.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06955 5fe802839409b4b91d2f5483baf7f50c 396 PRINTS PR00385 P450 superfamily signature 268 279 1.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 SUPERFAMILY SSF51445 49 402 1.79E-72 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Gene3D G3DSA:2.60.120.260 866 993 2.9E-23 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Pfam PF03422 Carbohydrate binding module (family 6) 881 986 1.0E-15 T 14-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 SUPERFAMILY SSF52279 404 751 1.31E-50 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 SMART SM01217 785 855 2.2E-30 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Gene3D G3DSA:2.60.40.10 752 865 3.4E-33 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Pfam PF14310 Fibronectin type III-like domain 785 855 4.3E-23 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 SMART SM00606 873 993 4.0E-15 T 14-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 SUPERFAMILY SSF49785 871 992 5.61E-19 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Gene3D G3DSA:3.40.50.1700 397 715 1.0E-187 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Gene3D G3DSA:3.20.20.300 64 751 1.0E-187 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 404 748 5.1E-62 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Gene3D G3DSA:2.60.120.380 478 607 1.0E-187 T 14-10-2018 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 PRINTS PR00133 Glycosyl hydrolase family 3 signature 123 142 4.7E-8 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 PRINTS PR00133 Glycosyl hydrolase family 3 signature 212 228 4.7E-8 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 SUPERFAMILY SSF50405 468 595 1.23E-8 T 14-10-2018 IPR008999 Actin-crosslinking A4R43_40510 6bc596de8eeaf1365e839c6a4fb2788e 993 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 103 365 4.2E-35 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_26335 04c46460da6e3b946b56c54645a49d7c 284 SUPERFAMILY SSF55961 5 139 9.58E-35 T 14-10-2018 A4R43_26335 04c46460da6e3b946b56c54645a49d7c 284 SUPERFAMILY SSF55961 164 280 1.55E-11 T 14-10-2018 A4R43_26335 04c46460da6e3b946b56c54645a49d7c 284 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 134 1.8E-12 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_26335 04c46460da6e3b946b56c54645a49d7c 284 Gene3D G3DSA:3.30.530.20 1 157 1.0E-39 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_26335 04c46460da6e3b946b56c54645a49d7c 284 Gene3D G3DSA:3.30.530.20 161 284 9.2E-8 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_13840 85704612f5617595fba8f274f1d2435d 515 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 213 496 24.808 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4R43_13840 85704612f5617595fba8f274f1d2435d 515 Gene3D G3DSA:1.20.1250.20 5 201 1.6E-5 T 14-10-2018 A4R43_13840 85704612f5617595fba8f274f1d2435d 515 Gene3D G3DSA:3.40.50.150 275 497 2.5E-60 T 14-10-2018 A4R43_13840 85704612f5617595fba8f274f1d2435d 515 SUPERFAMILY SSF103473 10 199 2.22E-9 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_13840 85704612f5617595fba8f274f1d2435d 515 Pfam PF01564 Spermine/spermidine synthase domain 279 456 2.2E-34 T 14-10-2018 A4R43_13840 85704612f5617595fba8f274f1d2435d 515 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 297 310 - T 14-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4R43_13840 85704612f5617595fba8f274f1d2435d 515 SUPERFAMILY SSF53335 219 487 1.79E-63 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_18890 fe0fe226f24731f491cf2bcb74019a9d 250 SUPERFAMILY SSF55781 82 243 9.42E-35 T 14-10-2018 A4R43_18890 fe0fe226f24731f491cf2bcb74019a9d 250 Pfam PF01614 Bacterial transcriptional regulator 125 243 2.8E-15 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_18890 fe0fe226f24731f491cf2bcb74019a9d 250 SMART SM00346 8 97 0.0015 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_18890 fe0fe226f24731f491cf2bcb74019a9d 250 Pfam PF09339 IclR helix-turn-helix domain 10 57 8.8E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_18890 fe0fe226f24731f491cf2bcb74019a9d 250 Gene3D G3DSA:1.10.10.10 6 69 1.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18890 fe0fe226f24731f491cf2bcb74019a9d 250 Gene3D G3DSA:3.30.450.40 73 249 1.9E-53 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_18890 fe0fe226f24731f491cf2bcb74019a9d 250 SUPERFAMILY SSF46785 8 75 1.15E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2222 2238 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF55048 685 739 1.7E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF55048 2710 2765 1.07E-8 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF52151 2567 2855 3.66E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00826 6356 6511 9.1E-62 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00826 2932 3094 1.7E-70 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00826 912 1072 1.4E-82 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF47336 5412 5524 2.62E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 6627 6809 2.17E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF55048 4696 4752 9.55E-9 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF55048 6135 6189 3.01E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.30.70.3290 4514 4890 1.3E-131 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4005 4020 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.50.720 6631 7076 3.9E-125 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 6818 7048 1.91E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF08659 KR domain 6822 6998 4.8E-60 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF08659 KR domain 5142 5316 3.7E-57 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF08659 KR domain 3699 3877 1.2E-58 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF08659 KR domain 1697 1872 2.4E-58 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00698 Acyl transferase domain 2570 2883 9.4E-48 T 14-10-2018 IPR014043 Acyl transferase A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00698 Acyl transferase domain 562 864 9.6E-53 T 14-10-2018 IPR014043 Acyl transferase A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00698 Acyl transferase domain 6016 6306 8.3E-47 T 14-10-2018 IPR014043 Acyl transferase A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00698 Acyl transferase domain 4577 4860 1.6E-43 T 14-10-2018 IPR014043 Acyl transferase A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF52151 560 833 3.4E-75 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00825 Beta-ketoacyl synthase 4071 4492 5.8E-223 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00825 Beta-ketoacyl synthase 5511 5932 3.8E-216 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00825 Beta-ketoacyl synthase 37 461 3.0E-212 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00825 Beta-ketoacyl synthase 2069 2485 8.4E-202 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM01294 1976 2043 2.1E-5 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM01294 7101 7168 1.5E-5 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM01294 3979 4046 2.8E-5 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM01294 5419 5486 3.1E-6 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF47336 7094 7178 2.88E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.30.70.3290 5949 6335 1.1E-132 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.30.70.3290 2500 2910 2.8E-138 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.47.10 5504 5948 1.1E-183 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.47.10 4062 4513 5.6E-188 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.47.10 27 472 7.6E-183 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF47336 1970 2082 1.83E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF50129 1406 1524 4.56E-27 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 1691 1941 3.39E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 3695 3932 4.92E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.30.70.3290 477 892 1.2E-155 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00829 1391 1687 1.9E-171 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00829 3393 3689 4.5E-171 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 1189 1369 3.35E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.50.11460 3210 3372 1.3E-35 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.50.11460 1190 1370 8.8E-49 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF13602 Zinc-binding dehydrogenase 3568 3689 4.8E-15 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF13602 Zinc-binding dehydrogenase 1566 1687 2.6E-13 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5142 5318 5.9E-55 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3699 3879 1.2E-63 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1697 1874 5.0E-56 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6822 7000 2.8E-62 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4442 4555 1.7E-14 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2435 2545 1.7E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5882 5969 1.8E-12 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 521 7.1E-14 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 3208 3372 9.06E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF47336 3973 4084 3.8E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF52151 6014 6292 8.63E-71 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1412 1467 7.5E-5 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3413 3469 1.1E-4 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 1492 1658 5.3E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF53901 32 398 1.22E-102 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5669 5685 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF53901 4067 4430 1.51E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.50.720 1692 1936 7.9E-68 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.50.720 3693 3938 2.1E-71 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.10.129.110 6345 6625 1.4E-85 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.10.129.110 901 1187 2.5E-111 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.10.129.110 2921 3206 3.1E-101 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.366.10 6014 6291 1.1E-132 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.366.10 2568 2868 2.8E-138 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.366.10 560 848 1.2E-155 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.366.10 4577 4845 1.3E-131 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2002 2017 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5509 5756 3.9E-87 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 1.2E-87 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2067 2309 4.8E-83 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4069 4316 2.6E-89 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:1.10.1200.10 1954 2048 3.5E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4324 4439 8.6E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2317 2432 4.3E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 408 2.6E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5764 5879 3.3E-45 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:1.10.1200.10 3960 4053 2.4E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:1.10.1200.10 5401 5492 7.6E-32 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:1.10.1200.10 7082 7175 1.8E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.90.180.10 1373 1691 1.5E-116 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.90.180.10 3375 3692 3.8E-116 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 4952 5132 5.51E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF50129 3408 3526 1.38E-27 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4579 4842 4.0E-103 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2570 2865 4.5E-107 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 562 845 9.6E-116 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6016 6288 9.7E-100 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4229 4245 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.50.720 4907 5385 1.9E-150 T 14-10-2018 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5445 5460 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Gene3D G3DSA:3.40.47.10 2052 2485 7.2E-180 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF14765 Polyketide synthase dehydratase 912 1181 4.2E-58 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF14765 Polyketide synthase dehydratase 2932 3198 2.9E-48 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF14765 Polyketide synthase dehydratase 6356 6617 6.3E-39 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF53901 5508 5876 8.84E-101 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 3493 3660 3.83E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00550 Phosphopantetheine attachment site 7102 7168 6.0E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00550 Phosphopantetheine attachment site 3980 4046 1.1E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00550 Phosphopantetheine attachment site 1979 2043 4.1E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 Pfam PF00550 Phosphopantetheine attachment site 5420 5486 1.9E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF53901 2064 2431 2.51E-97 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00823 Phosphopantetheine attachment site 3978 4050 1.6E-33 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00823 Phosphopantetheine attachment site 7100 7172 5.8E-32 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00823 Phosphopantetheine attachment site 1975 2047 3.3E-32 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SMART SM00823 Phosphopantetheine attachment site 5418 5490 1.0E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF52151 4576 4830 4.97E-63 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 SUPERFAMILY SSF51735 5138 5379 2.05E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38455 4b6ab4bdb977a6fee3f7e63df894e9c4 7257 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7127 7142 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_14965 738aef8743b772009c2966cc82fd4811 388 SUPERFAMILY SSF56349 166 371 1.27E-19 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_14965 738aef8743b772009c2966cc82fd4811 388 Pfam PF00589 Phage integrase family 177 370 3.7E-15 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_14965 738aef8743b772009c2966cc82fd4811 388 Gene3D G3DSA:1.10.443.10 165 382 1.3E-19 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_29885 738aef8743b772009c2966cc82fd4811 388 SUPERFAMILY SSF56349 166 371 1.27E-19 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_29885 738aef8743b772009c2966cc82fd4811 388 Pfam PF00589 Phage integrase family 177 370 3.7E-15 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_29885 738aef8743b772009c2966cc82fd4811 388 Gene3D G3DSA:1.10.443.10 165 382 1.3E-19 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_30280 738aef8743b772009c2966cc82fd4811 388 SUPERFAMILY SSF56349 166 371 1.27E-19 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_30280 738aef8743b772009c2966cc82fd4811 388 Pfam PF00589 Phage integrase family 177 370 3.7E-15 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_30280 738aef8743b772009c2966cc82fd4811 388 Gene3D G3DSA:1.10.443.10 165 382 1.3E-19 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 Gene3D G3DSA:2.40.37.10 17 366 2.9E-84 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 27 255 5.6E-46 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 SUPERFAMILY SSF50621 234 373 1.09E-28 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 256 351 1.3E-10 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 SUPERFAMILY SSF51419 16 257 4.42E-60 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_16195 29cd0225f76baab333133001eeb3097c 381 PRINTS PR01182 Ornithine decarboxylase signature 43 70 4.0E-15 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 PRINTS PR01182 Ornithine decarboxylase signature 87 111 4.0E-15 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 PRINTS PR01182 Ornithine decarboxylase signature 315 325 4.0E-15 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 PRINTS PR01182 Ornithine decarboxylase signature 117 139 4.0E-15 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 Gene3D G3DSA:3.20.20.10 24 257 2.9E-84 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_16195 29cd0225f76baab333133001eeb3097c 381 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 45 63 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A4R43_16195 29cd0225f76baab333133001eeb3097c 381 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 198 213 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A4R43_16195 29cd0225f76baab333133001eeb3097c 381 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 45 63 1.3E-18 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 245 264 1.3E-18 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 65 77 1.3E-18 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_16195 29cd0225f76baab333133001eeb3097c 381 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 167 180 1.3E-18 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_17730 92e8673e0d3ee44724a1c9ac70d773c5 340 Gene3D G3DSA:3.40.190.10 35 337 5.3E-102 T 14-10-2018 A4R43_17730 92e8673e0d3ee44724a1c9ac70d773c5 340 SMART SM00062 32 265 4.9E-4 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_17730 92e8673e0d3ee44724a1c9ac70d773c5 340 Gene3D G3DSA:3.40.190.10 114 227 5.3E-102 T 14-10-2018 A4R43_17730 92e8673e0d3ee44724a1c9ac70d773c5 340 Pfam PF09084 NMT1/THI5 like 47 265 9.3E-28 T 14-10-2018 IPR015168 SsuA/THI5-like A4R43_17730 92e8673e0d3ee44724a1c9ac70d773c5 340 SUPERFAMILY SSF53850 32 286 1.65E-42 T 14-10-2018 A4R43_35460 37bf9db8bcc63e8baef31b2cea55b454 359 Gene3D G3DSA:3.90.550.10 2 248 1.9E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35460 37bf9db8bcc63e8baef31b2cea55b454 359 Pfam PF00483 Nucleotidyl transferase 9 235 3.0E-42 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4R43_35460 37bf9db8bcc63e8baef31b2cea55b454 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 305 336 0.0015 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_35460 37bf9db8bcc63e8baef31b2cea55b454 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 286 0.0011 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_35460 37bf9db8bcc63e8baef31b2cea55b454 359 Gene3D G3DSA:2.160.10.10 303 358 5.5E-9 T 14-10-2018 A4R43_35460 37bf9db8bcc63e8baef31b2cea55b454 359 SUPERFAMILY SSF53448 9 310 1.35E-67 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35460 37bf9db8bcc63e8baef31b2cea55b454 359 Gene3D G3DSA:2.160.10.10 250 302 5.6E-6 T 14-10-2018 A4R43_28785 0ceb4d116c650d9dda30a6a02add8824 374 SUPERFAMILY SSF55874 257 367 5.02E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_28785 0ceb4d116c650d9dda30a6a02add8824 374 Pfam PF07730 Histidine kinase 177 243 2.6E-17 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_28785 0ceb4d116c650d9dda30a6a02add8824 374 SMART SM00387 281 370 2.3E-4 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_28785 0ceb4d116c650d9dda30a6a02add8824 374 Gene3D G3DSA:3.30.565.10 249 369 9.1E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03955 d19e2f6bc4ee80caad1fca505c679731 283 Pfam PF13649 Methyltransferase domain 93 186 8.9E-12 T 14-10-2018 A4R43_03955 d19e2f6bc4ee80caad1fca505c679731 283 SUPERFAMILY SSF53335 13 258 4.58E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_03955 d19e2f6bc4ee80caad1fca505c679731 283 Gene3D G3DSA:3.40.50.150 10 283 4.1E-70 T 14-10-2018 A4R43_34175 2d05a51ff1e9c250174cc5980e032fa9 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 272 1.1E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_34175 2d05a51ff1e9c250174cc5980e032fa9 283 Gene3D G3DSA:1.10.3720.10 10 269 3.6E-59 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_34175 2d05a51ff1e9c250174cc5980e032fa9 283 SUPERFAMILY SSF161098 11 281 2.43E-67 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 Pfam PF00072 Response regulator receiver domain 2 105 6.7E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 4.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 4.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 4.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 SMART SM00421 140 197 2.4E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 Gene3D G3DSA:3.40.50.12740 1 203 1.8E-64 T 14-10-2018 A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 SUPERFAMILY SSF52172 2 124 8.11E-27 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 SMART SM00448 1 105 9.6E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 SUPERFAMILY SSF46894 134 203 2.75E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_27475 0f2dd951444eb87eb8597853bc457e5f 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 197 4.8E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 Gene3D G3DSA:1.10.10.10 1 73 1.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 6.8E-21 T 14-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 Gene3D G3DSA:1.10.60.10 74 140 6.5E-29 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 Gene3D G3DSA:2.30.30.90 151 229 3.2E-11 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 SUPERFAMILY SSF46785 2 62 1.99E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 SUPERFAMILY SSF50037 130 227 3.2E-17 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 2.9E-28 T 14-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 SUPERFAMILY SSF47979 65 137 3.66E-26 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 SMART SM00529 26 125 9.5E-44 T 14-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A4R43_16685 e71c4fd8ba3ad0aedb8e7c7d5c2372b1 231 Pfam PF04023 FeoA domain 162 211 7.8E-6 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 SUPERFAMILY SSF53067 3 156 5.83E-23 T 14-10-2018 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 Gene3D G3DSA:3.90.640.10 203 290 5.6E-96 T 14-10-2018 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 PRINTS PR00301 70kDa heat shock protein signature 2 15 5.3E-6 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 PRINTS PR00301 70kDa heat shock protein signature 177 187 5.3E-6 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 PRINTS PR00301 70kDa heat shock protein signature 309 325 5.3E-6 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 Gene3D G3DSA:3.30.420.40 165 340 5.6E-96 T 14-10-2018 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 Pfam PF00012 Hsp70 protein 87 351 1.3E-28 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 Gene3D G3DSA:3.30.420.40 5 350 5.6E-96 T 14-10-2018 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 312 326 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_16975 4e80f655ecd33195c2d25363403bc4d2 645 SUPERFAMILY SSF53067 166 354 3.34E-31 T 14-10-2018 A4R43_17870 f1bacc0fd26d0a264dbff5879ec5fb14 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17870 f1bacc0fd26d0a264dbff5879ec5fb14 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17870 f1bacc0fd26d0a264dbff5879ec5fb14 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 2.5E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17870 f1bacc0fd26d0a264dbff5879ec5fb14 200 SUPERFAMILY SSF46689 2 86 4.14E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17870 f1bacc0fd26d0a264dbff5879ec5fb14 200 SUPERFAMILY SSF48498 83 192 5.19E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_17870 f1bacc0fd26d0a264dbff5879ec5fb14 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_17870 f1bacc0fd26d0a264dbff5879ec5fb14 200 Gene3D G3DSA:1.10.357.10 1 198 9.5E-46 T 14-10-2018 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 363 372 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 Gene3D G3DSA:1.10.630.10 20 424 1.4E-118 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 311 338 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 154 170 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 171 186 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 108 119 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 370 381 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 361 370 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 214 236 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 294 305 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00359 B-class P450 signature 339 354 2.8E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 Pfam PF00067 Cytochrome P450 293 387 2.1E-19 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00385 P450 superfamily signature 259 276 1.9E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00385 P450 superfamily signature 294 305 1.9E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00385 P450 superfamily signature 370 381 1.9E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 PRINTS PR00385 P450 superfamily signature 361 370 1.9E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_14115 a3efa397889a884707434d00dbc0bcfb 427 SUPERFAMILY SSF48264 36 418 3.41E-86 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24550 2f4f89b3e1d40941c17542b74170634a 485 Pfam PF00589 Phage integrase family 204 387 4.0E-7 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_24550 2f4f89b3e1d40941c17542b74170634a 485 SUPERFAMILY SSF56349 200 445 4.71E-20 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_24550 2f4f89b3e1d40941c17542b74170634a 485 Gene3D G3DSA:1.10.150.130 36 133 1.7E-10 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_24550 2f4f89b3e1d40941c17542b74170634a 485 Gene3D G3DSA:1.10.443.10 154 445 3.4E-28 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_24550 2f4f89b3e1d40941c17542b74170634a 485 SUPERFAMILY SSF56349 37 280 1.29E-10 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_24550 2f4f89b3e1d40941c17542b74170634a 485 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 51 122 2.5E-9 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 64 358 2.7E-67 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 SUPERFAMILY SSF49785 458 594 2.34E-36 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 SMART SM00939 373 589 1.8E-36 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 557 572 1.8E-22 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 50 60 1.8E-22 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 68 77 1.8E-22 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 34 46 1.8E-22 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 237 253 1.8E-22 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 85 101 1.8E-22 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 Gene3D G3DSA:3.40.50.1820 287 420 9.8E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 Gene3D G3DSA:3.40.50.1820 48 272 3.4E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 385 586 8.0E-39 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 SUPERFAMILY SSF53474 32 408 3.03E-80 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16710 a2edbca5b1515fd731f505e68fae60fc 603 Gene3D G3DSA:2.60.120.260 439 592 8.5E-41 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_38540 ffbc030ac4daea38c2085358efe64ad5 339 PIRSF PIRSF001455 28 332 7.2E-81 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4R43_38540 ffbc030ac4daea38c2085358efe64ad5 339 Gene3D G3DSA:1.20.1090.10 163 324 2.8E-39 T 14-10-2018 A4R43_38540 ffbc030ac4daea38c2085358efe64ad5 339 Gene3D G3DSA:3.40.50.1970 1 162 3.8E-47 T 14-10-2018 A4R43_38540 ffbc030ac4daea38c2085358efe64ad5 339 Pfam PF01761 3-dehydroquinate synthase 60 300 4.1E-81 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4R43_38540 ffbc030ac4daea38c2085358efe64ad5 339 SUPERFAMILY SSF56796 1 330 3.14E-89 T 14-10-2018 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 SUPERFAMILY SSF53738 256 362 3.14E-28 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 SUPERFAMILY SSF53738 156 254 5.89E-29 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 SUPERFAMILY SSF53738 4 179 1.61E-46 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 252 3.2E-19 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 135 1.3E-40 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 364 4.5E-31 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Gene3D G3DSA:3.40.120.10 173 361 1.8E-65 T 14-10-2018 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 437 4.8E-13 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 443 44.26 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 SUPERFAMILY SSF55957 356 442 5.76E-22 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 1.0E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.0E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 1.0E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Gene3D G3DSA:3.40.120.10 3 154 2.2E-46 T 14-10-2018 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Gene3D G3DSA:3.30.310.50 369 444 6.6E-26 T 14-10-2018 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 Gene3D G3DSA:3.40.120.10 255 338 1.8E-65 T 14-10-2018 A4R43_34105 7ef05579ebdc9aa4ceb6f95825f3fe18 444 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 441 1.8E-179 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_36470 1ea12e0792d5b9e552c7d77c134953e5 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 131 1.4E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_36470 1ea12e0792d5b9e552c7d77c134953e5 143 SUPERFAMILY SSF54593 10 133 1.17E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_36470 1ea12e0792d5b9e552c7d77c134953e5 143 Gene3D G3DSA:3.10.180.10 6 141 7.7E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 SUPERFAMILY SSF52172 1 129 2.7E-29 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 Pfam PF00072 Response regulator receiver domain 4 115 2.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 SMART SM00421 137 194 2.5E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 SMART SM00448 2 115 7.0E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 SUPERFAMILY SSF46894 130 200 3.4E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 9.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 9.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 9.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 Gene3D G3DSA:3.40.50.2300 2 136 1.0E-30 T 14-10-2018 A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 Gene3D G3DSA:1.10.10.10 137 200 1.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07275 5b45dda0c59364a78cc7200de688fb46 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 3.6E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03755 e1f1164d292a568c53f15c9fe3b2a569 366 SUPERFAMILY SSF50129 11 352 2.89E-35 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_03755 e1f1164d292a568c53f15c9fe3b2a569 366 Gene3D G3DSA:3.40.50.720 177 305 4.3E-70 T 14-10-2018 A4R43_03755 e1f1164d292a568c53f15c9fe3b2a569 366 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 38 158 5.7E-22 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_03755 e1f1164d292a568c53f15c9fe3b2a569 366 Pfam PF00107 Zinc-binding dehydrogenase 201 318 2.6E-16 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_03755 e1f1164d292a568c53f15c9fe3b2a569 366 SUPERFAMILY SSF51735 164 323 1.13E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03755 e1f1164d292a568c53f15c9fe3b2a569 366 TIGRFAM TIGR03366 HpnZ_proposed: putative phosphonate catabolism associated alcohol dehydrogenase 38 338 3.3E-117 T 14-10-2018 IPR017743 Alcohol dehydrogenase, phosphonate catabolism-associated, putative A4R43_03755 e1f1164d292a568c53f15c9fe3b2a569 366 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 71 85 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_03755 e1f1164d292a568c53f15c9fe3b2a569 366 Gene3D G3DSA:3.90.180.10 36 350 4.3E-70 T 14-10-2018 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 ProSitePatterns PS01233 Urocanase signature. 434 449 - T 14-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 PIRSF PIRSF001423 1 550 2.9E-278 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 Pfam PF17392 Urocanase C-terminal domain 344 538 2.9E-93 T 14-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 Gene3D G3DSA:3.40.50.10730 135 341 1.4E-246 T 14-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 Pfam PF17391 Urocanase N-terminal domain 5 131 6.2E-59 T 14-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 TIGRFAM TIGR01228 hutU: urocanate hydratase 3 546 8.7E-277 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 Gene3D G3DSA:3.40.1770.10 13 534 1.4E-246 T 14-10-2018 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 Pfam PF01175 Urocanase Rossmann-like domain 134 341 2.5E-84 T 14-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 Hamap MF_00577 Urocanate hydratase [hutU]. 2 548 50.185 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21875 3bf19768b46e83777f62eba07742b2ad 550 SUPERFAMILY SSF111326 3 547 4.71E-249 T 14-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_20705 71b3016b0e0f0fc41d4e9a9799fa4228 513 Pfam PF00899 ThiF family 275 395 4.2E-20 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4R43_20705 71b3016b0e0f0fc41d4e9a9799fa4228 513 SUPERFAMILY SSF69572 279 396 4.45E-18 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A4R43_20705 71b3016b0e0f0fc41d4e9a9799fa4228 513 Gene3D G3DSA:3.40.50.720 263 481 1.9E-19 T 14-10-2018 A4R43_22870 8efd4a92e7310ef6481786cb59256d1c 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 228 6.4E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_22870 8efd4a92e7310ef6481786cb59256d1c 404 SUPERFAMILY SSF56645 8 256 2.75E-48 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_22870 8efd4a92e7310ef6481786cb59256d1c 404 Gene3D G3DSA:2.40.110.10 132 249 5.9E-38 T 14-10-2018 A4R43_22870 8efd4a92e7310ef6481786cb59256d1c 404 Gene3D G3DSA:1.20.140.10 250 403 1.6E-33 T 14-10-2018 A4R43_22870 8efd4a92e7310ef6481786cb59256d1c 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 396 1.2E-35 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_22870 8efd4a92e7310ef6481786cb59256d1c 404 SUPERFAMILY SSF47203 244 398 1.93E-35 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_15300 0cb1a6e68472fa28924a0007a5cc42f4 142 Gene3D G3DSA:2.30.110.10 5 142 4.4E-45 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_15300 0cb1a6e68472fa28924a0007a5cc42f4 142 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 67 - T 14-10-2018 IPR010916 TonB box, conserved site A4R43_15300 0cb1a6e68472fa28924a0007a5cc42f4 142 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 28 140 1.4E-31 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_15300 0cb1a6e68472fa28924a0007a5cc42f4 142 Pfam PF04075 F420H(2)-dependent quinone reductase 19 141 2.9E-33 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_15300 0cb1a6e68472fa28924a0007a5cc42f4 142 SUPERFAMILY SSF50475 31 121 2.16E-5 T 14-10-2018 A4R43_27680 b6dbe49995363b5139a8562179e8f495 162 SUPERFAMILY SSF46785 16 121 6.92E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_27680 b6dbe49995363b5139a8562179e8f495 162 Pfam PF12802 MarR family 31 90 2.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_27680 b6dbe49995363b5139a8562179e8f495 162 Gene3D G3DSA:1.10.10.10 11 96 3.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10380 74302670d282f04c2fa6f626483ec706 307 Gene3D G3DSA:2.70.98.10 20 306 9.3E-78 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_10380 74302670d282f04c2fa6f626483ec706 307 SUPERFAMILY SSF74650 18 301 1.44E-62 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A4R43_10380 74302670d282f04c2fa6f626483ec706 307 Pfam PF01263 Aldose 1-epimerase 29 300 4.7E-51 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 405 460 1.2E-10 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 SUPERFAMILY SSF54637 1036 1133 6.96E-6 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 285 400 1.3E-35 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 SUPERFAMILY SSF53901 5 444 3.39E-74 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Pfam PF14765 Polyketide synthase dehydratase 893 1141 9.4E-19 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Gene3D G3DSA:3.30.70.250 630 694 1.3E-37 T 14-10-2018 A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 SMART SM00825 Beta-ketoacyl synthase 8 448 7.4E-85 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 SUPERFAMILY SSF52151 532 796 2.04E-27 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Pfam PF00698 Acyl transferase domain 588 773 2.0E-15 T 14-10-2018 IPR014043 Acyl transferase A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Gene3D G3DSA:3.10.129.110 895 1139 4.9E-16 T 14-10-2018 A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 190 206 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 536 801 2.7E-11 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Gene3D G3DSA:3.40.47.10 3 481 7.3E-149 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 277 2.7E-58 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_14760 c115b2e281ee26c09a7ccb955ccb6457 1287 Gene3D G3DSA:3.40.366.10 581 778 1.3E-37 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_41500 73c65b235df3a43d7ee8122f54778039 378 SUPERFAMILY SSF55124 182 281 3.18E-7 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_41500 73c65b235df3a43d7ee8122f54778039 378 SUPERFAMILY SSF55124 22 102 4.42E-22 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_41500 73c65b235df3a43d7ee8122f54778039 378 SUPERFAMILY SSF56014 301 360 1.11E-6 T 14-10-2018 A4R43_41500 73c65b235df3a43d7ee8122f54778039 378 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 41 88 4.4E-14 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_41500 73c65b235df3a43d7ee8122f54778039 378 Gene3D G3DSA:3.90.480.10 38 136 1.6E-14 T 14-10-2018 A4R43_00585 2fdbb5c3369757875d0da97467fe6dff 112 Pfam PF03551 Transcriptional regulator PadR-like family 20 91 1.1E-23 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_00585 2fdbb5c3369757875d0da97467fe6dff 112 Gene3D G3DSA:1.10.10.10 6 112 3.9E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00585 2fdbb5c3369757875d0da97467fe6dff 112 SUPERFAMILY SSF46785 16 110 1.31E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_29960 735200cb92ff108745a5790f408de784 557 Gene3D G3DSA:3.30.300.310 453 556 3.3E-33 T 14-10-2018 A4R43_29960 735200cb92ff108745a5790f408de784 557 Gene3D G3DSA:3.40.50.12780 13 452 2.4E-89 T 14-10-2018 A4R43_29960 735200cb92ff108745a5790f408de784 557 Pfam PF00501 AMP-binding enzyme 38 457 1.3E-76 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_29960 735200cb92ff108745a5790f408de784 557 SUPERFAMILY SSF56801 7 553 1.57E-126 T 14-10-2018 A4R43_29960 735200cb92ff108745a5790f408de784 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 467 541 5.7E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_15890 c957a3f115ce7b4747b80cbb48abf5e0 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 262 1.7E-58 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_15890 c957a3f115ce7b4747b80cbb48abf5e0 263 Gene3D G3DSA:1.10.12.10 206 263 7.3E-29 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_15890 c957a3f115ce7b4747b80cbb48abf5e0 263 Gene3D G3DSA:3.90.226.10 4 205 7.1E-77 T 14-10-2018 A4R43_15890 c957a3f115ce7b4747b80cbb48abf5e0 263 SUPERFAMILY SSF52096 2 263 7.38E-83 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_00505 9d58c5478ca67befa483f380d4691cff 131 SUPERFAMILY SSF54593 7 130 9.35E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_00505 9d58c5478ca67befa483f380d4691cff 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 126 1.0E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_00505 9d58c5478ca67befa483f380d4691cff 131 Gene3D G3DSA:3.10.180.10 4 131 9.3E-41 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_03130 c7b77c004933c4b1e8b23fb069fb86dc 385 SUPERFAMILY SSF81606 183 379 1.07E-8 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03130 c7b77c004933c4b1e8b23fb069fb86dc 385 Gene3D G3DSA:3.60.40.10 163 382 2.7E-36 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03130 c7b77c004933c4b1e8b23fb069fb86dc 385 SMART SM00331 166 381 5.9E-10 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03130 c7b77c004933c4b1e8b23fb069fb86dc 385 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 193 381 6.9E-28 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.5E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.5E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.5E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.5E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.5E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 Gene3D G3DSA:3.40.50.720 3 252 3.9E-80 T 14-10-2018 A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 3.6E-61 T 14-10-2018 A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 SUPERFAMILY SSF51735 7 250 1.02E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05355 e2b02b640bde439fa1dfc964c3ec2ff5 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 2.5E-5 T 14-10-2018 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 Gene3D G3DSA:2.40.110.10 131 243 1.2E-31 T 14-10-2018 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 225 4.8E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 134 146 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 385 2.1E-5 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 127 1.3E-20 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 SUPERFAMILY SSF47203 275 385 1.16E-6 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 SUPERFAMILY SSF56645 17 251 1.7E-62 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 Gene3D G3DSA:1.20.140.10 244 387 2.9E-13 T 14-10-2018 A4R43_29805 e0e958babf92043ab63c9f424c1b374a 388 Gene3D G3DSA:1.10.540.10 16 129 9.0E-25 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_18000 f1cf22fc4f43cb9874074072392b4317 168 SMART SM00347 24 122 5.0E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_18000 f1cf22fc4f43cb9874074072392b4317 168 Pfam PF01047 MarR family 37 81 3.7E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_18000 f1cf22fc4f43cb9874074072392b4317 168 Gene3D G3DSA:1.10.10.10 2 138 2.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18000 f1cf22fc4f43cb9874074072392b4317 168 SUPERFAMILY SSF46785 18 135 1.65E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03505 56ebc1c5e8ac18e46e52cfaee74257c7 542 Pfam PF13531 Bacterial extracellular solute-binding protein 39 301 1.8E-18 T 14-10-2018 A4R43_03505 56ebc1c5e8ac18e46e52cfaee74257c7 542 Pfam PF00092 von Willebrand factor type A domain 355 536 2.4E-7 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_03505 56ebc1c5e8ac18e46e52cfaee74257c7 542 SUPERFAMILY SSF53300 353 537 7.95E-19 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_03505 56ebc1c5e8ac18e46e52cfaee74257c7 542 SMART SM00327 349 539 1.6E-5 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_03505 56ebc1c5e8ac18e46e52cfaee74257c7 542 SUPERFAMILY SSF53850 35 317 3.02E-15 T 14-10-2018 A4R43_03505 56ebc1c5e8ac18e46e52cfaee74257c7 542 Gene3D G3DSA:3.40.50.410 351 539 2.0E-29 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_06890 b9d6cc44ef72a0ca3db8ad6eb01df4da 573 Gene3D G3DSA:3.30.1870.10 54 128 7.0E-39 T 14-10-2018 A4R43_06890 b9d6cc44ef72a0ca3db8ad6eb01df4da 573 Gene3D G3DSA:1.20.1440.30 129 262 7.0E-39 T 14-10-2018 A4R43_06890 b9d6cc44ef72a0ca3db8ad6eb01df4da 573 SUPERFAMILY SSF159501 18 357 5.75E-53 T 14-10-2018 A4R43_06890 b9d6cc44ef72a0ca3db8ad6eb01df4da 573 Gene3D G3DSA:3.40.1660.10 20 366 7.0E-39 T 14-10-2018 A4R43_06890 b9d6cc44ef72a0ca3db8ad6eb01df4da 573 Pfam PF05139 Erythromycin esterase 52 368 9.8E-39 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 A4R43_01885 946bd346efc93d6a1a51824500319e41 98 Pfam PF12840 Helix-turn-helix domain 14 71 2.4E-12 T 14-10-2018 A4R43_01885 946bd346efc93d6a1a51824500319e41 98 SUPERFAMILY SSF46785 10 91 2.1E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01885 946bd346efc93d6a1a51824500319e41 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 3.7E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01885 946bd346efc93d6a1a51824500319e41 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 3.7E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01885 946bd346efc93d6a1a51824500319e41 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 3.7E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01885 946bd346efc93d6a1a51824500319e41 98 Gene3D G3DSA:1.10.10.10 4 90 6.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01885 946bd346efc93d6a1a51824500319e41 98 SMART SM00418 14 91 1.2E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_20425 657d949ecd8142706c8b8f5d731752fb 273 Pfam PF00005 ABC transporter 34 184 1.9E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_20425 657d949ecd8142706c8b8f5d731752fb 273 SMART SM00382 42 243 2.2E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_20425 657d949ecd8142706c8b8f5d731752fb 273 Gene3D G3DSA:3.40.50.300 6 271 4.8E-54 T 14-10-2018 A4R43_20425 657d949ecd8142706c8b8f5d731752fb 273 SUPERFAMILY SSF52540 10 252 3.62E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21355 6c8ee10503963346f75edcb73675f78d 123 Pfam PF07883 Cupin domain 38 100 5.1E-14 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_21355 6c8ee10503963346f75edcb73675f78d 123 Gene3D G3DSA:2.60.120.10 11 118 1.3E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_21355 6c8ee10503963346f75edcb73675f78d 123 SUPERFAMILY SSF51182 13 111 8.15E-22 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 Pfam PF16919 Protein kinase G rubredoxin domain 97 182 4.2E-31 T 14-10-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 Gene3D G3DSA:1.10.510.10 271 439 2.8E-101 T 14-10-2018 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 Pfam PF00069 Protein kinase domain 184 389 7.4E-28 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 Gene3D G3DSA:1.25.40.10 466 786 7.2E-107 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 Gene3D G3DSA:3.30.200.20 135 270 2.8E-101 T 14-10-2018 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 SUPERFAMILY SSF48452 565 661 4.22E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 Gene3D G3DSA:1.25.40.10 457 628 7.2E-107 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 SMART SM00220 183 438 4.2E-17 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 Pfam PF16918 Protein kinase G tetratricopeptide repeat 454 789 5.1E-93 T 14-10-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A4R43_32470 a853c2a2f090ab3ca964ecebb88c835a 791 SUPERFAMILY SSF56112 173 440 1.31E-42 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_13310 41b16f17780c9adde854b5917fce03b5 291 SUPERFAMILY SSF52467 25 287 3.92E-70 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_13310 41b16f17780c9adde854b5917fce03b5 291 Gene3D G3DSA:3.30.1600.10 48 211 7.0E-73 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A4R43_13310 41b16f17780c9adde854b5917fce03b5 291 Pfam PF02146 Sir2 family 39 241 5.4E-43 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 A4R43_13310 41b16f17780c9adde854b5917fce03b5 291 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 16 286 60.979 T 14-10-2018 IPR026587 Sirtuin, class II Reactome: R-HSA-2151201 A4R43_13310 41b16f17780c9adde854b5917fce03b5 291 Gene3D G3DSA:3.40.50.1220 33 281 7.0E-73 T 14-10-2018 A4R43_28950 832edf07f50498b28c51e56fb87b05b1 393 SUPERFAMILY SSF51419 21 280 7.48E-19 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_28950 832edf07f50498b28c51e56fb87b05b1 393 Gene3D G3DSA:3.20.20.10 24 265 7.8E-51 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_28950 832edf07f50498b28c51e56fb87b05b1 393 Pfam PF01168 Alanine racemase, N-terminal domain 21 266 2.8E-13 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_07265 dcf13f3c4c4e6804c8c2523cb9267e33 135 Pfam PF12079 Protein of unknown function (DUF3558) 7 132 1.5E-9 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_11980 bd7a57b795abb9af251a4cd6a462f5c9 533 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 516 1.4E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_11980 bd7a57b795abb9af251a4cd6a462f5c9 533 SUPERFAMILY SSF56801 15 528 3.4E-155 T 14-10-2018 A4R43_11980 bd7a57b795abb9af251a4cd6a462f5c9 533 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_11980 bd7a57b795abb9af251a4cd6a462f5c9 533 Gene3D G3DSA:3.30.300.310 428 531 3.3E-32 T 14-10-2018 A4R43_11980 bd7a57b795abb9af251a4cd6a462f5c9 533 Pfam PF00501 AMP-binding enzyme 26 432 1.1E-104 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_11980 bd7a57b795abb9af251a4cd6a462f5c9 533 Gene3D G3DSA:3.40.50.12780 12 425 2.6E-114 T 14-10-2018 A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 Pfam PF08220 DeoR-like helix-turn-helix domain 18 64 4.2E-5 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 Gene3D G3DSA:3.30.450.40 105 336 1.1E-41 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 Gene3D G3DSA:1.10.10.10 1 86 1.3E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 Pfam PF01628 HrcA protein C terminal domain 105 323 1.4E-62 T 14-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 SUPERFAMILY SSF46785 4 84 2.56E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 5 336 1.3E-97 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 Gene3D G3DSA:3.30.390.60 129 230 1.1E-41 T 14-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 SUPERFAMILY SSF55781 73 339 4.12E-57 T 14-10-2018 A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 PIRSF PIRSF005485 1 340 3.0E-104 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4R43_39635 268396b747c4d2956a412fe8f399ebfd 340 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 3 330 27.853 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4R43_12390 1b98f2dbf57c348113de1ec602e284bb 194 Gene3D G3DSA:1.10.357.10 71 194 3.0E-21 T 14-10-2018 A4R43_12390 1b98f2dbf57c348113de1ec602e284bb 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 6.4E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_12390 1b98f2dbf57c348113de1ec602e284bb 194 Gene3D G3DSA:1.10.10.60 1 66 7.2E-26 T 14-10-2018 A4R43_12390 1b98f2dbf57c348113de1ec602e284bb 194 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 116 194 2.4E-6 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_12390 1b98f2dbf57c348113de1ec602e284bb 194 SUPERFAMILY SSF48498 84 193 8.35E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_12390 1b98f2dbf57c348113de1ec602e284bb 194 SUPERFAMILY SSF46689 2 82 9.23E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 141 218 1.9E-22 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 150 157 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 SUPERFAMILY SSF55594 141 224 4.32E-22 T 14-10-2018 IPR035895 HPr-like superfamily A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 Pfam PF00381 PTS HPr component phosphorylation site 141 218 5.5E-22 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 SUPERFAMILY SSF53062 4 123 3.53E-29 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 121 3.9E-36 T 14-10-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 Pfam PF03610 PTS system fructose IIA component 5 116 1.2E-24 T 14-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 Gene3D G3DSA:3.40.50.510 1 127 2.9E-41 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 PRINTS PR00107 Phosphocarrier protein signature 175 190 4.1E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 PRINTS PR00107 Phosphocarrier protein signature 150 166 4.1E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 PRINTS PR00107 Phosphocarrier protein signature 190 207 4.1E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_22245 6893bc861bfc8e2150c20361a0109270 224 Gene3D G3DSA:3.30.1340.10 139 224 7.8E-24 T 14-10-2018 IPR035895 HPr-like superfamily A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Gene3D G3DSA:2.40.50.140 339 410 6.7E-29 T 14-10-2018 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Gene3D G3DSA:1.10.150.20 454 532 8.6E-13 T 14-10-2018 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 SUPERFAMILY SSF52113 623 697 3.76E-16 T 14-10-2018 IPR036420 BRCT domain superfamily A4R43_20070 6665de03be44224b6311c9c36b07b954 716 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 352 367 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Gene3D G3DSA:1.10.150.20 533 614 2.2E-28 T 14-10-2018 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 33 689 3.2E-242 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Gene3D G3DSA:3.40.50.10190 619 699 1.4E-21 T 14-10-2018 IPR036420 BRCT domain superfamily A4R43_20070 6665de03be44224b6311c9c36b07b954 716 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 134 163 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site A4R43_20070 6665de03be44224b6311c9c36b07b954 716 SMART SM00532 25 470 2.4E-255 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Pfam PF12826 Helix-hairpin-helix motif 539 601 2.6E-22 T 14-10-2018 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 428 456 9.4E-8 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 SUPERFAMILY SSF47781 425 612 1.07E-49 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_20070 6665de03be44224b6311c9c36b07b954 716 SUPERFAMILY SSF50249 338 421 2.06E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 342 419 3.4E-31 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 SUPERFAMILY SSF56091 24 339 4.96E-115 T 14-10-2018 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 PIRSF PIRSF001604 20 698 7.4E-237 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Gene3D G3DSA:1.10.287.610 15 89 3.9E-26 T 14-10-2018 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Gene3D G3DSA:3.30.470.90 90 338 1.7E-102 T 14-10-2018 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 27 339 3.8E-122 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 623 690 3.7E-12 T 14-10-2018 IPR001357 BRCT domain A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Hamap MF_01588 DNA ligase [ligA]. 24 694 50.473 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4R43_20070 6665de03be44224b6311c9c36b07b954 716 SMART SM00292 620 697 1.2E-12 T 14-10-2018 IPR001357 BRCT domain A4R43_20070 6665de03be44224b6311c9c36b07b954 716 Gene3D G3DSA:2.20.70.80 412 451 1.3E-6 T 14-10-2018 A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 5.9E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 5.9E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 5.9E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 5.9E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 5.9E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 236 1.5E-61 T 14-10-2018 A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 SUPERFAMILY SSF51735 2 237 4.85E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 Gene3D G3DSA:3.40.50.720 1 242 6.9E-71 T 14-10-2018 A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06135 39a358e8096cfd3d80670c25156fe0e1 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 189 0.0046 T 14-10-2018 A4R43_14340 a3e27a485bfc2dc74142508e39490c74 228 Pfam PF08713 DNA alkylation repair enzyme 10 226 2.9E-59 T 14-10-2018 IPR014825 DNA alkylation repair enzyme A4R43_14340 a3e27a485bfc2dc74142508e39490c74 228 Gene3D G3DSA:1.25.10.90 1 228 2.3E-73 T 14-10-2018 A4R43_14340 a3e27a485bfc2dc74142508e39490c74 228 SUPERFAMILY SSF48371 13 227 1.58E-51 T 14-10-2018 IPR016024 Armadillo-type fold A4R43_20610 49163471ff110312af97e8342a42573c 64 SUPERFAMILY SSF47598 26 62 6.23E-5 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4R43_20610 49163471ff110312af97e8342a42573c 64 Pfam PF01402 Ribbon-helix-helix protein, copG family 28 62 1.9E-6 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A4R43_00325 57a98a5b9a2ee3332d00076621d101fa 238 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 224 1.3E-49 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_00325 57a98a5b9a2ee3332d00076621d101fa 238 Gene3D G3DSA:3.90.226.10 6 237 1.4E-63 T 14-10-2018 A4R43_00325 57a98a5b9a2ee3332d00076621d101fa 238 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_00325 57a98a5b9a2ee3332d00076621d101fa 238 SUPERFAMILY SSF52096 3 233 7.03E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_02850 9544ea4ac8ec2fbdfca168a6017ca136 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.1E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_02850 9544ea4ac8ec2fbdfca168a6017ca136 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.1E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_02850 9544ea4ac8ec2fbdfca168a6017ca136 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_02850 9544ea4ac8ec2fbdfca168a6017ca136 204 Gene3D G3DSA:1.10.357.10 17 204 1.0E-40 T 14-10-2018 A4R43_02850 9544ea4ac8ec2fbdfca168a6017ca136 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 3.6E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_02850 9544ea4ac8ec2fbdfca168a6017ca136 204 SUPERFAMILY SSF46689 8 86 3.54E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38910 813ecc33b03e113b206f203db1c29fe3 161 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 9 153 3.0E-50 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_38910 813ecc33b03e113b206f203db1c29fe3 161 PIRSF PIRSF005384 7 155 2.0E-45 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_38910 813ecc33b03e113b206f203db1c29fe3 161 Pfam PF02502 Ribose/Galactose Isomerase 9 148 4.2E-44 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_38910 813ecc33b03e113b206f203db1c29fe3 161 SUPERFAMILY SSF89623 7 156 4.32E-49 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_38910 813ecc33b03e113b206f203db1c29fe3 161 Gene3D G3DSA:3.40.1400.10 5 161 2.5E-56 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_38910 813ecc33b03e113b206f203db1c29fe3 161 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 7 154 2.6E-63 T 14-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Pfam PF07516 SecA Wing and Scaffold domain 635 725 2.1E-11 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 SMART SM00958 236 344 5.2E-25 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Gene3D G3DSA:3.90.1440.10 232 354 1.8E-120 T 14-10-2018 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Gene3D G3DSA:3.40.50.300 30 401 1.8E-120 T 14-10-2018 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Pfam PF01043 SecA preprotein cross-linking domain 240 344 1.3E-19 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 PRINTS PR00906 SecA protein signature 66 90 1.1E-36 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 PRINTS PR00906 SecA protein signature 104 118 1.1E-36 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 PRINTS PR00906 SecA protein signature 120 130 1.1E-36 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 PRINTS PR00906 SecA protein signature 325 347 1.1E-36 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 PRINTS PR00906 SecA protein signature 173 193 1.1E-36 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 PRINTS PR00906 SecA protein signature 399 412 1.1E-36 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 PRINTS PR00906 SecA protein signature 362 379 1.1E-36 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 SUPERFAMILY SSF81767 241 350 7.72E-27 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 11 774 0.0 T 14-10-2018 IPR026389 Protein translocase subunit SecA, Actinobacteria-type A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 ProSitePatterns PS01312 SecA family signature. 486 501 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Pfam PF07517 SecA DEAD-like domain 13 387 1.6E-87 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 SUPERFAMILY SSF81886 585 732 1.7E-24 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 SUPERFAMILY SSF52540 13 401 3.12E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Hamap MF_01382 Protein translocase subunit SecA [secA]. 11 731 15.434 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Gene3D G3DSA:1.10.3060.10 584 735 6.0E-24 T 14-10-2018 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 SUPERFAMILY SSF52540 405 565 1.73E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 SMART SM00957 12 388 2.2E-140 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Gene3D G3DSA:3.40.50.300 505 578 3.7E-20 T 14-10-2018 A4R43_22180 88798f67a7acb590751a48e02a3f3945 778 Gene3D G3DSA:3.40.50.300 404 504 5.1E-35 T 14-10-2018 A4R43_41095 0d2643afff28092cc5f5efd411d47a48 448 SUPERFAMILY SSF53474 18 266 1.75E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41095 0d2643afff28092cc5f5efd411d47a48 448 Gene3D G3DSA:3.40.50.1820 37 274 9.5E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41095 0d2643afff28092cc5f5efd411d47a48 448 Pfam PF00326 Prolyl oligopeptidase family 110 270 3.4E-9 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_07925 587f5dba407b519997afa640159705ce 1783 Pfam PF00550 Phosphopantetheine attachment site 1641 1706 5.8E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07925 587f5dba407b519997afa640159705ce 1783 SMART SM01294 1640 1707 4.9E-6 T 14-10-2018 A4R43_07925 587f5dba407b519997afa640159705ce 1783 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 287 1.3E-94 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07925 587f5dba407b519997afa640159705ce 1783 SMART SM00823 Phosphopantetheine attachment site 1639 1711 1.5E-32 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07925 587f5dba407b519997afa640159705ce 1783 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 527 1.2E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07925 587f5dba407b519997afa640159705ce 1783 Pfam PF00698 Acyl transferase domain 562 870 9.2E-91 T 14-10-2018 IPR014043 Acyl transferase A4R43_07925 587f5dba407b519997afa640159705ce 1783 Gene3D G3DSA:3.30.70.3290 478 897 1.1E-160 T 14-10-2018 A4R43_07925 587f5dba407b519997afa640159705ce 1783 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 564 851 1.5E-116 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07925 587f5dba407b519997afa640159705ce 1783 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1666 1681 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07925 587f5dba407b519997afa640159705ce 1783 Pfam PF14765 Polyketide synthase dehydratase 909 1180 5.3E-58 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07925 587f5dba407b519997afa640159705ce 1783 SMART SM00825 Beta-ketoacyl synthase 39 464 7.8E-221 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07925 587f5dba407b519997afa640159705ce 1783 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 295 411 1.0E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07925 587f5dba407b519997afa640159705ce 1783 SUPERFAMILY SSF47336 1633 1714 5.76E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07925 587f5dba407b519997afa640159705ce 1783 SUPERFAMILY SSF55048 684 746 3.27E-13 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07925 587f5dba407b519997afa640159705ce 1783 Gene3D G3DSA:3.40.366.10 562 854 1.1E-160 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07925 587f5dba407b519997afa640159705ce 1783 Gene3D G3DSA:3.40.50.720 1184 1621 9.5E-122 T 14-10-2018 A4R43_07925 587f5dba407b519997afa640159705ce 1783 Gene3D G3DSA:1.10.1200.10 1622 1714 1.2E-35 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07925 587f5dba407b519997afa640159705ce 1783 SUPERFAMILY SSF51735 1188 1356 3.74E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07925 587f5dba407b519997afa640159705ce 1783 SMART SM00826 909 1068 3.5E-85 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07925 587f5dba407b519997afa640159705ce 1783 SUPERFAMILY SSF53901 33 460 7.5E-103 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07925 587f5dba407b519997afa640159705ce 1783 SUPERFAMILY SSF51735 1367 1614 2.76E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07925 587f5dba407b519997afa640159705ce 1783 Pfam PF08990 Erythronolide synthase docking 6 30 1.9E-7 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_07925 587f5dba407b519997afa640159705ce 1783 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 200 216 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07925 587f5dba407b519997afa640159705ce 1783 Gene3D G3DSA:3.10.129.110 901 1183 2.4E-111 T 14-10-2018 A4R43_07925 587f5dba407b519997afa640159705ce 1783 Gene3D G3DSA:3.40.47.10 28 475 9.6E-193 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07925 587f5dba407b519997afa640159705ce 1783 SUPERFAMILY SSF52151 561 843 4.19E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07925 587f5dba407b519997afa640159705ce 1783 Pfam PF08659 KR domain 1369 1540 1.2E-54 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07925 587f5dba407b519997afa640159705ce 1783 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1369 1541 5.3E-55 T 14-10-2018 A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 ProSitePatterns PS00018 EF-hand calcium-binding domain. 123 135 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 ProSitePatterns PS00018 EF-hand calcium-binding domain. 51 63 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 Gene3D G3DSA:1.10.238.10 1 159 6.5E-36 T 14-10-2018 A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 SMART SM00054 42 70 58.0 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 SMART SM00054 80 108 0.026 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 SMART SM00054 114 142 0.025 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 ProSitePatterns PS00018 EF-hand calcium-binding domain. 2 14 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 Pfam PF13499 EF-hand domain pair 82 138 1.6E-8 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 SUPERFAMILY SSF47473 1 151 1.29E-22 T 14-10-2018 IPR011992 EF-hand domain pair A4R43_18345 2a8c931b73d85e1081c7262755fc8b3b 166 ProSitePatterns PS00018 EF-hand calcium-binding domain. 89 101 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site A4R43_16175 e232b5138d164c6a403966afba82465c 149 Gene3D G3DSA:3.30.450.30 10 135 1.3E-41 T 14-10-2018 A4R43_16175 e232b5138d164c6a403966afba82465c 149 Pfam PF03259 Roadblock/LC7 domain 15 104 1.0E-20 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_16175 e232b5138d164c6a403966afba82465c 149 SMART SM00960 14 104 9.8E-29 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_16175 e232b5138d164c6a403966afba82465c 149 SUPERFAMILY SSF103196 7 132 7.85E-33 T 14-10-2018 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 180 469 7.8E-120 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 Gene3D G3DSA:3.40.50.720 1 181 4.9E-55 T 14-10-2018 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 SUPERFAMILY SSF51735 5 178 4.57E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 255 267 - T 14-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 SUPERFAMILY SSF48179 178 472 1.87E-114 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 7 470 8.3E-201 T 14-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 4.8E-79 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 251 278 4.8E-79 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 4.8E-79 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 169 197 4.8E-79 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 359 381 4.8E-79 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 4.8E-79 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 SMART SM01350 180 470 6.4E-192 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 172 2.5E-49 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 Gene3D G3DSA:1.20.5.320 438 473 2.3E-19 T 14-10-2018 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 PIRSF PIRSF000109 1 476 5.5E-196 T 14-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_27515 272e960a413cf6f377ab4cf4ed06e14f 479 Gene3D G3DSA:1.10.1040.10 182 437 8.2E-95 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 Gene3D G3DSA:3.40.50.620 1 223 4.3E-84 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 SMART SM00363 357 418 1.4E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 Pfam PF00579 tRNA synthetases class I (W and Y) 30 325 6.8E-78 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 SUPERFAMILY SSF55174 328 419 1.01E-16 T 14-10-2018 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 422 42.738 T 14-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 163 178 8.5E-27 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 184 206 8.5E-27 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 8.5E-27 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 8.5E-27 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 420 1.6E-107 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 Gene3D G3DSA:1.10.240.10 224 328 4.0E-34 T 14-10-2018 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 Gene3D G3DSA:3.10.290.10 329 423 5.2E-29 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 51 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_14270 bf7210f589e93a2033bf27b0912c2374 423 SUPERFAMILY SSF52374 4 325 8.26E-96 T 14-10-2018 A4R43_02085 a7580266ceec233ac2ebfdb6ea144057 135 SUPERFAMILY SSF51182 10 111 6.55E-20 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_02085 a7580266ceec233ac2ebfdb6ea144057 135 Pfam PF07883 Cupin domain 44 110 5.9E-15 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_02085 a7580266ceec233ac2ebfdb6ea144057 135 Gene3D G3DSA:2.60.120.10 28 123 5.6E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 Gene3D G3DSA:3.30.360.10 128 273 1.2E-123 T 14-10-2018 A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 SMART SM00859 4 117 3.7E-4 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 PIRSF PIRSF015689 1 301 5.2E-129 T 14-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 301 128.153 T 14-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 100 5.8E-8 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 128 273 3.4E-63 T 14-10-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 Gene3D G3DSA:3.40.50.720 5 291 1.2E-123 T 14-10-2018 A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 SUPERFAMILY SSF51735 5 152 8.68E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 4 297 3.3E-131 T 14-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 A4R43_11395 49d7bf4d38ef9eb343f58718736dc49e 301 SUPERFAMILY SSF55347 128 273 3.73E-59 T 14-10-2018 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 1.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 SMART SM00448 8 121 7.0E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 Gene3D G3DSA:3.40.50.12740 8 222 1.6E-66 T 14-10-2018 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 Pfam PF00072 Response regulator receiver domain 10 122 2.5E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 SUPERFAMILY SSF52172 8 140 1.71E-37 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 SUPERFAMILY SSF46894 154 223 1.36E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 SMART SM00421 159 216 2.8E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30900 47c6cb8bfb84e82ecc86fbff4a1fd6c1 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 215 2.9E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_01425 11268ca95b39320d21752afe4704add2 265 Pfam PF14011 EspG family 14 260 5.2E-34 T 14-10-2018 IPR025734 EspG family A4R43_06845 65677e7a6f2c36223c5b7e2127542e0e 636 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 37 172 1.3E-19 T 14-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal A4R43_06845 65677e7a6f2c36223c5b7e2127542e0e 636 Gene3D G3DSA:1.20.58.460 504 636 9.1E-9 T 14-10-2018 A4R43_06845 65677e7a6f2c36223c5b7e2127542e0e 636 Gene3D G3DSA:3.20.20.80 175 496 1.1E-102 T 14-10-2018 A4R43_06845 65677e7a6f2c36223c5b7e2127542e0e 636 Gene3D G3DSA:3.30.379.10 25 173 1.6E-25 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4R43_06845 65677e7a6f2c36223c5b7e2127542e0e 636 SUPERFAMILY SSF51445 177 501 3.26E-99 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_06845 65677e7a6f2c36223c5b7e2127542e0e 636 Pfam PF07555 beta-N-acetylglucosaminidase 179 488 1.3E-101 T 14-10-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 A4R43_06845 65677e7a6f2c36223c5b7e2127542e0e 636 SUPERFAMILY SSF55545 37 174 3.4E-14 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4R43_02740 74005e7f9dd5177fd7795366bb76918d 474 SMART SM00345 24 83 6.5E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02740 74005e7f9dd5177fd7795366bb76918d 474 SUPERFAMILY SSF46785 16 90 2.99E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02740 74005e7f9dd5177fd7795366bb76918d 474 Gene3D G3DSA:3.90.1150.10 107 454 7.0E-79 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_02740 74005e7f9dd5177fd7795366bb76918d 474 SUPERFAMILY SSF53383 95 458 8.74E-79 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_02740 74005e7f9dd5177fd7795366bb76918d 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 83 5.6E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02740 74005e7f9dd5177fd7795366bb76918d 474 Gene3D G3DSA:1.10.10.10 18 106 4.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02740 74005e7f9dd5177fd7795366bb76918d 474 Pfam PF00155 Aminotransferase class I and II 145 452 5.1E-31 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_02740 74005e7f9dd5177fd7795366bb76918d 474 Gene3D G3DSA:3.40.640.10 144 356 7.0E-79 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 Gene3D G3DSA:3.90.230.10 4 285 7.7E-113 T 14-10-2018 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 39.457 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 Pfam PF00557 Metallopeptidase family M24 48 276 3.7E-50 T 14-10-2018 IPR000994 Peptidase M24 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 SUPERFAMILY SSF55920 4 284 1.16E-85 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 42 283 3.4E-88 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 2.8E-18 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 2.8E-18 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 2.8E-18 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 2.8E-18 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_18295 77d630644c2a3a595d1a34ec8e95b0e8 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 12 756 0.0 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 9 317 5.8E-114 T 14-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 7 756 34.646 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 Gene3D G3DSA:3.20.20.210 11 524 0.0 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 431 751 8.8E-145 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 Gene3D G3DSA:3.20.20.210 390 754 0.0 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 SUPERFAMILY SSF51726 408 755 2.09E-112 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 SUPERFAMILY SSF51726 9 376 3.01E-98 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_05175 f61ef2544b95c390ef149adfb38170d7 758 PIRSF PIRSF000382 6 758 0.0 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4R43_26035 f37837a7b2649dbcf964c3906e63acba 77 SMART SM00346 1 72 3.5E-7 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_26035 f37837a7b2649dbcf964c3906e63acba 77 Gene3D G3DSA:1.10.10.10 1 63 8.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26035 f37837a7b2649dbcf964c3906e63acba 77 SUPERFAMILY SSF46785 1 65 1.34E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26035 f37837a7b2649dbcf964c3906e63acba 77 Pfam PF09339 IclR helix-turn-helix domain 1 46 3.1E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 Gene3D G3DSA:3.20.20.100 1 277 2.3E-119 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 SUPERFAMILY SSF51430 6 269 8.77E-99 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 Pfam PF00248 Aldo/keto reductase family 24 261 9.7E-54 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.0E-51 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 PRINTS PR00069 Aldo-keto reductase signature 159 188 1.0E-51 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 PRINTS PR00069 Aldo-keto reductase signature 125 142 1.0E-51 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 PRINTS PR00069 Aldo-keto reductase signature 197 221 1.0E-51 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 PRINTS PR00069 Aldo-keto reductase signature 93 111 1.0E-51 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38380 a39854df36cb3dd2a43f3a50585540f5 277 PIRSF PIRSF000097 2 273 4.7E-88 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_09875 357b054c9e2ffd1e9696d481e15cf0bd 334 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 21 333 5.3E-111 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4R43_09875 357b054c9e2ffd1e9696d481e15cf0bd 334 Gene3D G3DSA:3.20.20.70 2 334 5.4E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_09875 357b054c9e2ffd1e9696d481e15cf0bd 334 PIRSF PIRSF001361 3 334 1.0E-118 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4R43_09875 357b054c9e2ffd1e9696d481e15cf0bd 334 Pfam PF00793 DAHP synthetase I family 33 321 1.4E-73 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4R43_09875 357b054c9e2ffd1e9696d481e15cf0bd 334 SUPERFAMILY SSF51569 4 330 2.09E-104 T 14-10-2018 A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 10 680 0.0 T 14-10-2018 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 SUPERFAMILY SSF51735 416 677 2.12E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 15 210 4.6E-21 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 SUPERFAMILY SSF53639 8 213 1.04E-27 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 SMART SM01007 11 213 3.0E-31 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 Gene3D G3DSA:3.40.225.10 8 218 7.8E-49 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 432 674 1.1E-42 T 14-10-2018 A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 Gene3D G3DSA:3.40.50.720 404 677 5.2E-59 T 14-10-2018 A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 544 560 1.7E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 570 589 1.7E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 591 608 1.7E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 496 507 1.7E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 424 441 1.7E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05530 ffd471a8f4f484c36d95055854c1d1e6 680 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 638 658 1.7E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18530 41eb2fe2041172a4bd3c7869f8df2dc2 289 Pfam PF00248 Aldo/keto reductase family 24 287 5.6E-63 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_18530 41eb2fe2041172a4bd3c7869f8df2dc2 289 Gene3D G3DSA:3.20.20.100 15 289 6.7E-88 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_18530 41eb2fe2041172a4bd3c7869f8df2dc2 289 PRINTS PR00069 Aldo-keto reductase signature 54 78 7.3E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_18530 41eb2fe2041172a4bd3c7869f8df2dc2 289 PRINTS PR00069 Aldo-keto reductase signature 119 137 7.3E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_18530 41eb2fe2041172a4bd3c7869f8df2dc2 289 PRINTS PR00069 Aldo-keto reductase signature 221 245 7.3E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_18530 41eb2fe2041172a4bd3c7869f8df2dc2 289 PRINTS PR00069 Aldo-keto reductase signature 150 167 7.3E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_18530 41eb2fe2041172a4bd3c7869f8df2dc2 289 SUPERFAMILY SSF51430 16 287 5.11E-80 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_39570 ead0aff7e63d9240f2c073a259c16aa8 186 SUPERFAMILY SSF46689 1 37 3.64E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_39570 ead0aff7e63d9240f2c073a259c16aa8 186 SUPERFAMILY SSF48498 46 185 1.56E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_39570 ead0aff7e63d9240f2c073a259c16aa8 186 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 40 185 7.6E-23 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_39570 ead0aff7e63d9240f2c073a259c16aa8 186 Gene3D G3DSA:1.10.357.10 1 186 1.9E-53 T 14-10-2018 A4R43_00395 9550a0c84ce073f5a59792ac31add3bd 440 Pfam PF02687 FtsX-like permease family 344 432 6.5E-6 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_00395 9550a0c84ce073f5a59792ac31add3bd 440 Pfam PF02687 FtsX-like permease family 83 173 4.5E-7 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 Gene3D G3DSA:3.40.50.300 1 240 3.2E-53 T 14-10-2018 A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 Gene3D G3DSA:3.40.50.300 260 500 5.9E-46 T 14-10-2018 A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 SUPERFAMILY SSF52540 271 485 2.07E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 SMART SM00382 31 219 2.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 SMART SM00382 285 478 0.0033 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 SUPERFAMILY SSF52540 5 229 3.59E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 Pfam PF00005 ABC transporter 22 171 5.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_10410 492a04da090dfd07b26ea82bad810b09 504 Pfam PF00005 ABC transporter 278 430 6.8E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_05705 876eb3f5b9535835dd609ced25008ea8 222 SUPERFAMILY SSF48008 85 216 5.23E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_05705 876eb3f5b9535835dd609ced25008ea8 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 3.6E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05705 876eb3f5b9535835dd609ced25008ea8 222 SMART SM00895 88 212 5.9E-16 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_05705 876eb3f5b9535835dd609ced25008ea8 222 SMART SM00345 20 78 1.2E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05705 876eb3f5b9535835dd609ced25008ea8 222 SUPERFAMILY SSF46785 12 82 5.9E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05705 876eb3f5b9535835dd609ced25008ea8 222 Gene3D G3DSA:1.20.120.530 82 219 1.9E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_05705 876eb3f5b9535835dd609ced25008ea8 222 Gene3D G3DSA:1.10.10.10 2 79 3.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05705 876eb3f5b9535835dd609ced25008ea8 222 Pfam PF07729 FCD domain 88 211 4.3E-23 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_31850 44e8fce5b1ad84d894539ba6bdffe80f 228 Gene3D G3DSA:3.40.50.880 2 223 1.4E-60 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_31850 44e8fce5b1ad84d894539ba6bdffe80f 228 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 221 1.6E-81 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31850 44e8fce5b1ad84d894539ba6bdffe80f 228 SMART SM01211 2 222 1.6E-120 T 14-10-2018 A4R43_31850 44e8fce5b1ad84d894539ba6bdffe80f 228 SUPERFAMILY SSF52317 3 220 2.15E-69 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_31850 44e8fce5b1ad84d894539ba6bdffe80f 228 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 220 38.427 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31850 44e8fce5b1ad84d894539ba6bdffe80f 228 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 207 9.3E-35 T 14-10-2018 A4R43_31850 44e8fce5b1ad84d894539ba6bdffe80f 228 PIRSF PIRSF001586 1 225 4.8E-79 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_27870 915fefd9a9fc8e43647c769577368fd2 356 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 217 226 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A4R43_27870 915fefd9a9fc8e43647c769577368fd2 356 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 350 3.2E-90 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4R43_27870 915fefd9a9fc8e43647c769577368fd2 356 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 353 51.295 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4R43_27870 915fefd9a9fc8e43647c769577368fd2 356 SUPERFAMILY SSF53383 22 348 4.57E-81 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_27870 915fefd9a9fc8e43647c769577368fd2 356 Gene3D G3DSA:3.90.1150.10 14 346 3.7E-130 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_27870 915fefd9a9fc8e43647c769577368fd2 356 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 9 354 48.429 T 14-10-2018 IPR024892 Putative phenylalanine aminotransferase A4R43_27870 915fefd9a9fc8e43647c769577368fd2 356 Pfam PF00155 Aminotransferase class I and II 29 345 1.4E-48 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_27870 915fefd9a9fc8e43647c769577368fd2 356 Gene3D G3DSA:3.40.640.10 40 265 3.7E-130 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_40100 ce924c3a9ffd4650e1d509be647a67d0 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 101 9.0E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_40100 ce924c3a9ffd4650e1d509be647a67d0 317 SMART SM00829 10 315 2.8E-17 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_40100 ce924c3a9ffd4650e1d509be647a67d0 317 Pfam PF13602 Zinc-binding dehydrogenase 187 315 2.1E-20 T 14-10-2018 A4R43_40100 ce924c3a9ffd4650e1d509be647a67d0 317 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A4R43_40100 ce924c3a9ffd4650e1d509be647a67d0 317 Gene3D G3DSA:3.90.180.10 10 311 1.4E-79 T 14-10-2018 A4R43_40100 ce924c3a9ffd4650e1d509be647a67d0 317 Gene3D G3DSA:3.40.50.720 128 262 1.4E-79 T 14-10-2018 A4R43_40100 ce924c3a9ffd4650e1d509be647a67d0 317 SUPERFAMILY SSF51735 117 245 2.15E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40100 ce924c3a9ffd4650e1d509be647a67d0 317 SUPERFAMILY SSF50129 1 149 1.23E-30 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_21335 7a5bb220c3f4c3583aaa8fa9951abae9 424 SUPERFAMILY SSF51197 5 420 4.3E-138 T 14-10-2018 A4R43_21335 7a5bb220c3f4c3583aaa8fa9951abae9 424 Gene3D G3DSA:2.60.120.330 6 422 2.5E-132 T 14-10-2018 IPR027443 Isopenicillin N synthase-like A4R43_21335 7a5bb220c3f4c3583aaa8fa9951abae9 424 Pfam PF07350 Protein of unknown function (DUF1479) 13 420 9.6E-128 T 14-10-2018 IPR010856 Protein of unknown function DUF1479 A4R43_31365 6c100a7d4ad8eeb74da97484a0ddd2f0 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31365 6c100a7d4ad8eeb74da97484a0ddd2f0 186 SUPERFAMILY SSF46689 8 84 1.69E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31365 6c100a7d4ad8eeb74da97484a0ddd2f0 186 Gene3D G3DSA:1.10.357.10 1 186 6.1E-47 T 14-10-2018 A4R43_31365 6c100a7d4ad8eeb74da97484a0ddd2f0 186 SUPERFAMILY SSF48498 92 183 7.79E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_06605 ae3f559da44e47ad06c5833a91a6cc67 306 SUPERFAMILY SSF51556 21 300 1.61E-70 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_06605 ae3f559da44e47ad06c5833a91a6cc67 306 Gene3D G3DSA:3.20.20.140 19 305 1.0E-64 T 14-10-2018 A4R43_06605 ae3f559da44e47ad06c5833a91a6cc67 306 Pfam PF04909 Amidohydrolase 21 299 1.3E-59 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_11640 fa149b01b5f0545d868dc3a2df471046 391 SUPERFAMILY SSF55874 288 389 7.15E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_11640 fa149b01b5f0545d868dc3a2df471046 391 Pfam PF07730 Histidine kinase 184 250 1.3E-18 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_11640 fa149b01b5f0545d868dc3a2df471046 391 SMART SM00387 290 390 3.7E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_11640 fa149b01b5f0545d868dc3a2df471046 391 Gene3D G3DSA:3.30.565.10 256 389 9.7E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27195 27de5dea80efd8c607bf816ec37f0256 253 SMART SM00849 31 182 1.1E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_27195 27de5dea80efd8c607bf816ec37f0256 253 Pfam PF00753 Metallo-beta-lactamase superfamily 29 182 6.0E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_27195 27de5dea80efd8c607bf816ec37f0256 253 Gene3D G3DSA:3.60.15.10 7 186 3.9E-38 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_27195 27de5dea80efd8c607bf816ec37f0256 253 SUPERFAMILY SSF56281 10 251 1.44E-44 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_27195 27de5dea80efd8c607bf816ec37f0256 253 Gene3D G3DSA:1.10.10.10 190 252 1.9E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19085 98bd0f86d32f31e707832e1375ea6743 407 Gene3D G3DSA:1.20.1720.10 24 403 1.4E-109 T 14-10-2018 A4R43_19085 98bd0f86d32f31e707832e1375ea6743 407 ProSitePatterns PS00216 Sugar transport proteins signature 1. 78 94 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_19085 98bd0f86d32f31e707832e1375ea6743 407 Pfam PF07690 Major Facilitator Superfamily 34 370 7.8E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_19085 98bd0f86d32f31e707832e1375ea6743 407 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 22 401 3.9E-99 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 A4R43_19085 98bd0f86d32f31e707832e1375ea6743 407 SUPERFAMILY SSF103473 17 405 1.1E-64 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_11785 7cf9e4973a903b4fd341d0248623c1d0 344 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 7 285 7.1E-48 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11785 7cf9e4973a903b4fd341d0248623c1d0 344 Pfam PF02470 MlaD protein 32 107 7.2E-12 T 14-10-2018 IPR003399 Mce/MlaD A4R43_11785 7cf9e4973a903b4fd341d0248623c1d0 344 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 159 296 1.3E-6 T 14-10-2018 IPR024516 Mammalian cell entry, C-terminal A4R43_41640 4f151a24e8ff0b683f933d7b489b4775 332 SUPERFAMILY SSF52922 188 318 5.5E-41 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_41640 4f151a24e8ff0b683f933d7b489b4775 332 Gene3D G3DSA:3.40.50.970 1 196 5.9E-77 T 14-10-2018 A4R43_41640 4f151a24e8ff0b683f933d7b489b4775 332 Pfam PF02779 Transketolase, pyrimidine binding domain 3 176 3.4E-45 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_41640 4f151a24e8ff0b683f933d7b489b4775 332 SMART SM00861 3 178 2.4E-68 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_41640 4f151a24e8ff0b683f933d7b489b4775 332 Pfam PF02780 Transketolase, C-terminal domain 192 312 6.3E-42 T 14-10-2018 IPR033248 Transketolase, C-terminal domain A4R43_41640 4f151a24e8ff0b683f933d7b489b4775 332 Gene3D G3DSA:3.40.50.920 197 318 1.6E-44 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_41640 4f151a24e8ff0b683f933d7b489b4775 332 SUPERFAMILY SSF52518 3 182 6.38E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_12650 1aabee28b805aa9eb3b8c866d1d8fbfe 423 Pfam PF00171 Aldehyde dehydrogenase family 161 337 8.7E-26 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_12650 1aabee28b805aa9eb3b8c866d1d8fbfe 423 Gene3D G3DSA:3.40.309.10 195 338 2.4E-31 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_12650 1aabee28b805aa9eb3b8c866d1d8fbfe 423 SUPERFAMILY SSF53720 37 398 7.59E-34 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_12650 1aabee28b805aa9eb3b8c866d1d8fbfe 423 Gene3D G3DSA:3.40.605.10 114 193 2.4E-31 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 SMART SM00304 183 242 1.0E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 SMART SM00388 250 317 1.7E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 SUPERFAMILY SSF55874 306 486 5.76E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 316 2.9E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 SUPERFAMILY SSF47384 241 315 4.51E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 2.3E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 2.3E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 2.3E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 2.3E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 Gene3D G3DSA:1.10.287.130 187 319 1.8E-24 T 14-10-2018 A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 Gene3D G3DSA:3.30.565.10 348 490 1.6E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 SMART SM00387 375 486 6.5E-41 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_11445 0f69d6a827054d9543ed75f46325be19 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 376 485 5.3E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_17165 49c5c7e4007ad22ef0c1146f1f17c929 254 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 80 3.2E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17165 49c5c7e4007ad22ef0c1146f1f17c929 254 SUPERFAMILY SSF46689 26 90 2.17E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17165 49c5c7e4007ad22ef0c1146f1f17c929 254 Gene3D G3DSA:1.10.10.60 11 86 2.4E-25 T 14-10-2018 A4R43_17165 49c5c7e4007ad22ef0c1146f1f17c929 254 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 93 245 9.5E-18 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_17165 49c5c7e4007ad22ef0c1146f1f17c929 254 Gene3D G3DSA:1.10.357.10 88 247 8.4E-37 T 14-10-2018 A4R43_17165 49c5c7e4007ad22ef0c1146f1f17c929 254 SUPERFAMILY SSF48498 98 248 8.34E-25 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_23300 f05f314c603cb6a94e215f30c1848895 1106 SUPERFAMILY SSF53448 9 238 4.98E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_23300 f05f314c603cb6a94e215f30c1848895 1106 Gene3D G3DSA:3.90.550.10 6 243 6.0E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_23300 f05f314c603cb6a94e215f30c1848895 1106 Pfam PF00535 Glycosyl transferase family 2 12 139 2.8E-13 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 Gene3D G3DSA:3.30.930.10 104 420 2.0E-119 T 14-10-2018 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 Gene3D G3DSA:1.10.287.40 1 103 3.6E-22 T 14-10-2018 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 1.0E-25 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 416 38.971 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 PIRSF PIRSF001529 1 419 6.5E-143 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 SUPERFAMILY SSF55681 114 414 1.65E-88 T 14-10-2018 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 219 394 2.4E-27 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 SUPERFAMILY SSF46589 2 111 9.94E-27 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 PRINTS PR00981 Seryl-tRNA synthetase signature 329 345 4.2E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 PRINTS PR00981 Seryl-tRNA synthetase signature 272 285 4.2E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 PRINTS PR00981 Seryl-tRNA synthetase signature 312 325 4.2E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 PRINTS PR00981 Seryl-tRNA synthetase signature 347 363 4.2E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 PRINTS PR00981 Seryl-tRNA synthetase signature 260 272 4.2E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4R43_28355 580d1adcbc393eb05ea52a8bed8d1339 421 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 410 1.6E-135 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 Gene3D G3DSA:1.10.10.10 16 93 8.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 Pfam PF00155 Aminotransferase class I and II 120 376 6.9E-14 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 6.7E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 6.7E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 8.3E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 SUPERFAMILY SSF46785 23 87 5.97E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 Gene3D G3DSA:3.40.640.10 96 449 1.3E-97 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 SMART SM00345 24 83 3.8E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_20530 5a27147f92ade3da31efbf2be61a079a 465 SUPERFAMILY SSF53383 103 456 3.26E-68 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_21025 eb1ff98c75611bb02970a42af9e39345 382 Gene3D G3DSA:3.20.20.30 1 364 1.7E-133 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_21025 eb1ff98c75611bb02970a42af9e39345 382 Pfam PF00296 Luciferase-like monooxygenase 4 337 3.1E-88 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_21025 eb1ff98c75611bb02970a42af9e39345 382 SUPERFAMILY SSF51679 5 366 3.68E-94 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_06785 06c669b5e411cb40d18c2626132bd1bf 538 SUPERFAMILY SSF53850 58 533 1.65E-90 T 14-10-2018 A4R43_06785 06c669b5e411cb40d18c2626132bd1bf 538 PIRSF PIRSF002741 12 529 4.2E-70 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_06785 06c669b5e411cb40d18c2626132bd1bf 538 Gene3D G3DSA:3.40.190.10 63 509 1.0E-86 T 14-10-2018 A4R43_06785 06c669b5e411cb40d18c2626132bd1bf 538 Gene3D G3DSA:3.90.76.10 84 200 1.0E-86 T 14-10-2018 A4R43_06785 06c669b5e411cb40d18c2626132bd1bf 538 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 448 3.7E-67 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_06785 06c669b5e411cb40d18c2626132bd1bf 538 Gene3D G3DSA:3.10.105.10 294 507 1.0E-86 T 14-10-2018 A4R43_06785 06c669b5e411cb40d18c2626132bd1bf 538 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 102 124 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site A4R43_06560 7807f620de47824c28d2ffadd5e8ba5c 121 Gene3D G3DSA:1.10.10.10 1 108 3.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06560 7807f620de47824c28d2ffadd5e8ba5c 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 8.3E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_06560 7807f620de47824c28d2ffadd5e8ba5c 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 8.3E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_06560 7807f620de47824c28d2ffadd5e8ba5c 121 SMART SM00418 9 86 3.1E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_06560 7807f620de47824c28d2ffadd5e8ba5c 121 Pfam PF12840 Helix-turn-helix domain 9 65 2.5E-16 T 14-10-2018 A4R43_06560 7807f620de47824c28d2ffadd5e8ba5c 121 SUPERFAMILY SSF46785 3 104 4.12E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_16495 1039ba289705c3042421b1be9a0462df 215 Gene3D G3DSA:3.30.110.150 124 206 1.5E-27 T 14-10-2018 IPR038594 SepF-like superfamily A4R43_16495 1039ba289705c3042421b1be9a0462df 215 Pfam PF04472 Cell division protein SepF 127 198 4.0E-25 T 14-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A4R43_16495 1039ba289705c3042421b1be9a0462df 215 Hamap MF_01197 Cell division protein SepF [sepF]. 1 206 21.311 T 14-10-2018 IPR023052 Cell division protein SepF GO:0090529 A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 757 1330 8.7E-238 T 14-10-2018 IPR023837 EccCb-like, Actinobacteria A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 Pfam PF01580 FtsK/SpoIIIE family 450 566 1.1E-22 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 Pfam PF01580 FtsK/SpoIIIE family 816 1051 1.9E-54 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 SUPERFAMILY SSF52540 1087 1264 1.95E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 Gene3D G3DSA:3.40.50.300 225 376 2.4E-11 T 14-10-2018 A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 Gene3D G3DSA:3.40.50.300 779 1089 5.8E-92 T 14-10-2018 A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 SUPERFAMILY SSF52540 774 1026 9.0E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 SMART SM00382 475 638 10.0 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 SMART SM00382 836 1015 0.057 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 SUPERFAMILY SSF52540 440 697 4.91E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 698 2.2E-289 T 14-10-2018 IPR023836 EccCa-like, Actinobacteria A4R43_34050 7f7fbe127e1c2fc7b9b6626972a7cd08 1335 Gene3D G3DSA:3.40.50.300 1096 1332 7.4E-52 T 14-10-2018 A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 7.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 7.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 7.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 Gene3D G3DSA:3.40.190.10 170 269 7.7E-36 T 14-10-2018 A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 Gene3D G3DSA:3.40.190.10 98 277 7.7E-36 T 14-10-2018 A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 SUPERFAMILY SSF53850 94 299 1.41E-31 T 14-10-2018 A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 Gene3D G3DSA:1.10.10.10 3 94 2.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.4E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 Pfam PF03466 LysR substrate binding domain 94 294 9.7E-33 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_11155 15986415293969a50fb4d6f3b49c2981 307 SUPERFAMILY SSF46785 4 88 9.62E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 Gene3D G3DSA:1.10.10.10 1 105 3.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 5.7E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 5.7E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 5.7E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 SUPERFAMILY SSF46785 4 134 3.32E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 113 235 2.5E-21 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 SMART SM00418 3 78 1.6E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 SUPERFAMILY SSF55961 103 238 1.08E-31 T 14-10-2018 A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 Pfam PF12840 Helix-turn-helix domain 4 62 1.6E-14 T 14-10-2018 A4R43_20290 5252d38b38afe331dbd5f1dd55ed4408 253 Gene3D G3DSA:3.30.530.20 106 238 3.2E-34 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 SUPERFAMILY SSF53244 353 509 3.92E-47 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 Pfam PF01225 Mur ligase family, catalytic domain 46 120 5.7E-11 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 Gene3D G3DSA:3.40.1390.10 21 125 1.4E-30 T 14-10-2018 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 Gene3D G3DSA:3.90.190.20 355 512 4.3E-58 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 SUPERFAMILY SSF53623 126 351 3.43E-65 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 21 509 31.986 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 43 509 1.6E-143 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 Gene3D G3DSA:3.40.1190.10 126 354 3.4E-79 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 Pfam PF02875 Mur ligase family, glutamate ligase domain 353 437 9.8E-22 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 SUPERFAMILY SSF63418 40 124 1.7E-17 T 14-10-2018 IPR035911 MurE/MurF, N-terminal A4R43_16590 a4cb9b0f7b6db1b347aeba60d2f022ac 517 Pfam PF08245 Mur ligase middle domain 135 333 6.6E-44 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 Gene3D G3DSA:3.30.230.10 10 171 4.9E-9 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 500 3.3E-143 T 14-10-2018 IPR004482 Mg chelatase-related protein A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 393 2.4E-82 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 SMART SM00382 210 392 2.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 5.2E-37 T 14-10-2018 A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 405 500 7.4E-23 T 14-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 SUPERFAMILY SSF54211 7 168 1.33E-30 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 SUPERFAMILY SSF52540 187 500 9.7E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_18420 2034a02d1278922a2a8a98a113b9987d 505 Gene3D G3DSA:3.40.50.300 187 388 3.5E-43 T 14-10-2018 A4R43_18715 bf2bacf09937a16275bad5a9b6336816 612 PIRSF PIRSF001589 1 610 5.7E-140 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_18715 bf2bacf09937a16275bad5a9b6336816 612 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 537 1.5E-148 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_18715 bf2bacf09937a16275bad5a9b6336816 612 Pfam PF00733 Asparagine synthase 239 602 3.1E-86 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4R43_18715 bf2bacf09937a16275bad5a9b6336816 612 Pfam PF13537 Glutamine amidotransferase domain 48 169 4.5E-48 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4R43_18715 bf2bacf09937a16275bad5a9b6336816 612 SUPERFAMILY SSF52402 229 575 7.39E-64 T 14-10-2018 A4R43_18715 bf2bacf09937a16275bad5a9b6336816 612 SUPERFAMILY SSF56235 1 224 1.12E-64 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_18715 bf2bacf09937a16275bad5a9b6336816 612 Gene3D G3DSA:3.60.20.10 2 182 9.6E-64 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_28715 52098f817ef4d9766928e8aa668a05bf 205 SUPERFAMILY SSF55068 18 197 2.75E-78 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_28715 52098f817ef4d9766928e8aa668a05bf 205 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 32 193 38.099 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_28715 52098f817ef4d9766928e8aa668a05bf 205 Gene3D G3DSA:3.30.1060.10 1 202 3.4E-88 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_28715 52098f817ef4d9766928e8aa668a05bf 205 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 34 187 2.3E-65 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_28715 52098f817ef4d9766928e8aa668a05bf 205 Pfam PF01625 Peptide methionine sulfoxide reductase 35 187 8.7E-67 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_32955 1ba7e3560b843166a428fd1d6dab1d45 443 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 15 436 93.604 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A4R43_32955 1ba7e3560b843166a428fd1d6dab1d45 443 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 16 429 1.6E-175 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A4R43_32955 1ba7e3560b843166a428fd1d6dab1d45 443 Gene3D G3DSA:3.40.640.10 81 328 2.4E-153 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_32955 1ba7e3560b843166a428fd1d6dab1d45 443 Gene3D G3DSA:3.90.1150.10 19 424 2.4E-153 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_32955 1ba7e3560b843166a428fd1d6dab1d45 443 SUPERFAMILY SSF53383 13 432 2.02E-114 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_32955 1ba7e3560b843166a428fd1d6dab1d45 443 Pfam PF00202 Aminotransferase class-III 45 429 8.0E-82 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_05780 2e96d10f40a08a654b73e4e5c9a1e5ff 281 SUPERFAMILY SSF53927 5 272 1.86E-78 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_05780 2e96d10f40a08a654b73e4e5c9a1e5ff 281 Pfam PF02634 FdhD/NarQ family 26 272 3.8E-82 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4R43_05780 2e96d10f40a08a654b73e4e5c9a1e5ff 281 PIRSF PIRSF015626 1 275 2.7E-87 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4R43_05780 2e96d10f40a08a654b73e4e5c9a1e5ff 281 Gene3D G3DSA:3.40.140.10 127 277 3.4E-52 T 14-10-2018 A4R43_05780 2e96d10f40a08a654b73e4e5c9a1e5ff 281 Gene3D G3DSA:3.10.20.10 28 119 1.3E-6 T 14-10-2018 A4R43_05780 2e96d10f40a08a654b73e4e5c9a1e5ff 281 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 273 33.561 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4R43_05780 2e96d10f40a08a654b73e4e5c9a1e5ff 281 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 1.2E-49 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4R43_00090 1690dd5cef65347e46eaa18a413e2f66 356 Gene3D G3DSA:3.40.50.1820 43 345 1.1E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00090 1690dd5cef65347e46eaa18a413e2f66 356 Pfam PF12697 Alpha/beta hydrolase family 69 329 1.4E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_00090 1690dd5cef65347e46eaa18a413e2f66 356 SUPERFAMILY SSF53474 33 346 5.49E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08225 277cd1cf3cfd27fce563c5583cb13390 245 Gene3D G3DSA:3.40.50.150 1 216 4.6E-23 T 14-10-2018 A4R43_08225 277cd1cf3cfd27fce563c5583cb13390 245 Pfam PF08241 Methyltransferase domain 55 139 5.4E-10 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_08225 277cd1cf3cfd27fce563c5583cb13390 245 SUPERFAMILY SSF53335 8 188 8.76E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 SUPERFAMILY SSF52096 2 303 1.4E-59 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 Gene3D G3DSA:3.40.50.720 320 503 1.3E-68 T 14-10-2018 A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 Gene3D G3DSA:3.90.226.10 1 319 4.8E-112 T 14-10-2018 A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 SUPERFAMILY SSF48179 502 644 3.06E-16 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 207 3.5E-34 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 SUPERFAMILY SSF48179 630 719 4.08E-16 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 Gene3D G3DSA:1.10.1040.50 504 713 2.5E-63 T 14-10-2018 A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 503 603 2.0E-17 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 322 500 1.3E-61 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_22850 8dd36e228afcb7a16851638fbac273c5 722 SUPERFAMILY SSF51735 319 501 1.21E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 SMART SM00388 617 685 6.2E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Pfam PF00512 His Kinase A (phospho-acceptor) domain 618 684 7.1E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 SUPERFAMILY SSF52402 240 361 1.31E-12 T 14-10-2018 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Gene3D G3DSA:3.40.50.300 9 218 3.3E-99 T 14-10-2018 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Gene3D G3DSA:1.20.120.620 384 488 1.7E-17 T 14-10-2018 IPR038318 KdpD, transmembrane domain superfamily A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 10 219 2.9E-98 T 14-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 SUPERFAMILY SSF47384 607 685 1.63E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Pfam PF00582 Universal stress protein family 240 361 2.2E-6 T 14-10-2018 IPR006016 UspA A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 727 832 1.7E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 SMART SM00387 726 834 5.9E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Gene3D G3DSA:3.30.565.10 694 835 1.1E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 818 831 1.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 761 775 1.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 794 812 1.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 SUPERFAMILY SSF55874 674 833 5.5E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Gene3D G3DSA:1.10.287.130 604 687 1.1E-13 T 14-10-2018 A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Pfam PF13493 Domain of unknown function (DUF4118) 388 494 3.0E-27 T 14-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain A4R43_18690 9747d0ce171816efd291b951ec83fa34 839 Gene3D G3DSA:3.40.50.620 224 361 4.3E-9 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_11300 b0518f899bde2a1116389758bbfa040b 136 Pfam PF12796 Ankyrin repeats (3 copies) 41 112 5.9E-10 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain A4R43_11300 b0518f899bde2a1116389758bbfa040b 136 SMART SM00248 51 80 1.1E-4 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_11300 b0518f899bde2a1116389758bbfa040b 136 SMART SM00248 84 113 0.87 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_11300 b0518f899bde2a1116389758bbfa040b 136 SUPERFAMILY SSF48403 27 134 1.32E-20 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4R43_11300 b0518f899bde2a1116389758bbfa040b 136 Gene3D G3DSA:1.25.40.20 15 135 7.2E-25 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4R43_18465 1a77e85e1928f933fb28e3f6b6b0eed6 147 SUPERFAMILY SSF54565 2 94 6.54E-32 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18465 1a77e85e1928f933fb28e3f6b6b0eed6 147 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.761 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18465 1a77e85e1928f933fb28e3f6b6b0eed6 147 Gene3D G3DSA:3.30.1320.10 1 104 6.7E-29 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18465 1a77e85e1928f933fb28e3f6b6b0eed6 147 Pfam PF00886 Ribosomal protein S16 9 67 3.5E-22 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18465 1a77e85e1928f933fb28e3f6b6b0eed6 147 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 3.0E-30 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 182 3.8E-4 T 14-10-2018 A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 6.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 6.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 6.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 Gene3D G3DSA:3.40.50.720 2 246 4.0E-64 T 14-10-2018 A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 SUPERFAMILY SSF51735 3 245 1.05E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 Pfam PF00106 short chain dehydrogenase 3 188 6.6E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 8.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 8.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 8.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 8.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 PIRSF PIRSF000126 1 252 2.1E-71 T 14-10-2018 A4R43_31440 fbc2cb8df683f0120f29140e568416b3 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_11015 b6afdda1dbaa4142111444ecd00cbaaa 347 TIGRFAM TIGR00109 hemH: ferrochelatase 36 310 9.2E-41 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4R43_11015 b6afdda1dbaa4142111444ecd00cbaaa 347 Pfam PF00762 Ferrochelatase 4 310 6.4E-100 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4R43_11015 b6afdda1dbaa4142111444ecd00cbaaa 347 Gene3D G3DSA:3.40.50.1400 146 292 4.2E-119 T 14-10-2018 A4R43_11015 b6afdda1dbaa4142111444ecd00cbaaa 347 Hamap MF_00323 Ferrochelatase [hemH]. 2 311 30.965 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4R43_11015 b6afdda1dbaa4142111444ecd00cbaaa 347 Gene3D G3DSA:3.40.50.1400 6 307 4.2E-119 T 14-10-2018 A4R43_11015 b6afdda1dbaa4142111444ecd00cbaaa 347 SUPERFAMILY SSF53800 3 316 2.62E-85 T 14-10-2018 A4R43_08950 cd355abe75743f459eeeeffc7d01086e 302 SUPERFAMILY SSF52317 1 157 1.88E-39 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_08950 cd355abe75743f459eeeeffc7d01086e 302 Gene3D G3DSA:3.40.50.10740 3 153 6.6E-47 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal A4R43_08950 cd355abe75743f459eeeeffc7d01086e 302 Pfam PF02016 LD-carboxypeptidase 12 285 3.3E-65 T 14-10-2018 IPR003507 Peptidase family S66 A4R43_08950 cd355abe75743f459eeeeffc7d01086e 302 SUPERFAMILY SSF141986 146 292 1.83E-35 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily A4R43_08950 cd355abe75743f459eeeeffc7d01086e 302 Gene3D G3DSA:3.50.30.60 168 294 1.0E-35 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily A4R43_08950 cd355abe75743f459eeeeffc7d01086e 302 PIRSF PIRSF028757 1 300 2.4E-65 T 14-10-2018 IPR003507 Peptidase family S66 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 415 5.8E-150 T 14-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 268 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 Pfam PF00202 Aminotransferase class-III 19 408 5.2E-74 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 PIRSF PIRSF000521 2 127 3.4E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 PIRSF PIRSF000521 182 414 5.5E-28 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 PIRSF PIRSF000521 121 159 0.1 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 Gene3D G3DSA:3.40.640.10 54 315 3.3E-107 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 2 412 1.6E-197 T 14-10-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 Gene3D G3DSA:3.90.1150.10 9 407 3.3E-107 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_26280 8727840fdbc1f765339ba5aabfba8045 417 SUPERFAMILY SSF53383 9 411 6.57E-106 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 Pfam PF00486 Transcriptional regulatory protein, C terminal 13 82 2.9E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 SUPERFAMILY SSF46894 14 82 1.53E-10 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 SUPERFAMILY SSF48452 84 251 5.69E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 PRINTS PR00364 Disease resistance protein signature 344 358 2.2E-6 T 14-10-2018 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 PRINTS PR00364 Disease resistance protein signature 271 286 2.2E-6 T 14-10-2018 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 PRINTS PR00364 Disease resistance protein signature 447 461 2.2E-6 T 14-10-2018 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 SUPERFAMILY SSF48452 737 898 9.49E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 Gene3D G3DSA:3.40.50.300 249 397 1.3E-6 T 14-10-2018 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 SMART SM01043 89 233 1.7E-50 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 Pfam PF03704 Bacterial transcriptional activator domain 89 233 1.1E-41 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 Gene3D G3DSA:1.25.40.10 730 1008 7.6E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 Gene3D G3DSA:1.25.40.10 87 248 5.1E-50 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 SMART SM00862 11 82 5.7E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 SUPERFAMILY SSF52540 244 512 1.25E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06965 b3f7f2ec30bb23979ec5b21e87ac7611 1022 Gene3D G3DSA:1.10.10.10 1 84 4.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Pfam PF03704 Bacterial transcriptional activator domain 95 238 5.5E-40 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SMART SM00028 903 936 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SMART SM00028 739 772 3.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SMART SM00028 943 976 140.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SMART SM00028 824 857 45.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SMART SM00028 784 817 0.12 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Gene3D G3DSA:1.25.40.10 93 259 2.9E-46 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Gene3D G3DSA:1.25.40.10 778 866 1.2E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Pfam PF00931 NB-ARC domain 281 464 2.8E-10 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SUPERFAMILY SSF48452 675 813 2.66E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Pfam PF13374 Tetratricopeptide repeat 742 772 3.0E-5 T 14-10-2018 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SMART SM00382 279 417 7.5E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SUPERFAMILY SSF52540 256 517 3.92E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Gene3D G3DSA:1.25.40.10 867 988 6.3E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Gene3D G3DSA:1.25.40.10 572 777 1.9E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Gene3D G3DSA:1.10.10.10 1 90 1.6E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Gene3D G3DSA:3.40.50.300 260 376 1.6E-5 T 14-10-2018 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SMART SM01043 95 238 1.4E-47 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 PRINTS PR00364 Disease resistance protein signature 282 297 8.8E-8 T 14-10-2018 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 PRINTS PR00364 Disease resistance protein signature 360 374 8.8E-8 T 14-10-2018 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 PRINTS PR00364 Disease resistance protein signature 447 461 8.8E-8 T 14-10-2018 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Pfam PF13424 Tetratricopeptide repeat 785 853 3.5E-11 T 14-10-2018 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Pfam PF13424 Tetratricopeptide repeat 869 934 1.7E-11 T 14-10-2018 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SUPERFAMILY SSF48452 92 258 1.19E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SUPERFAMILY SSF46894 2 75 6.24E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 SUPERFAMILY SSF48452 782 974 1.45E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08040 85c0304395aee2c7dbdea403a38289dd 990 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 75 3.7E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_00305 be9bd57372cb896810746808b5af4c5e 322 Gene3D G3DSA:3.20.20.70 2 316 3.0E-82 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_00305 be9bd57372cb896810746808b5af4c5e 322 SUPERFAMILY SSF51412 6 312 4.12E-51 T 14-10-2018 A4R43_00305 be9bd57372cb896810746808b5af4c5e 322 Pfam PF03060 Nitronate monooxygenase 85 306 9.5E-37 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_00305 be9bd57372cb896810746808b5af4c5e 322 Pfam PF03060 Nitronate monooxygenase 7 80 9.2E-13 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_34435 e1029f4ebf124f0923dbef365aca5525 89 SUPERFAMILY SSF48600 8 71 7.78E-13 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_34435 e1029f4ebf124f0923dbef365aca5525 89 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 13 85 5.2E-31 T 14-10-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal A4R43_34435 e1029f4ebf124f0923dbef365aca5525 89 Gene3D G3DSA:1.20.59.10 3 89 2.5E-27 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_34435 e1029f4ebf124f0923dbef365aca5525 89 SMART SM00830 17 79 2.6E-5 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_34435 e1029f4ebf124f0923dbef365aca5525 89 Pfam PF01817 Chorismate mutase type II 17 72 5.8E-9 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_32350 128556e668560c1c84601145580cac2b 319 SUPERFAMILY SSF51445 42 271 8.86E-15 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_32350 128556e668560c1c84601145580cac2b 319 Gene3D G3DSA:3.20.20.80 30 289 5.5E-22 T 14-10-2018 A4R43_08880 3cfc26a682b49bcbdea4127e39bd08cd 172 SUPERFAMILY SSF160904 2 168 2.75E-33 T 14-10-2018 A4R43_08880 3cfc26a682b49bcbdea4127e39bd08cd 172 Gene3D G3DSA:1.10.3300.10 1 171 2.0E-39 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_08880 3cfc26a682b49bcbdea4127e39bd08cd 172 Pfam PF11706 CGNR zinc finger 127 169 1.0E-13 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_18720 de724294e33a750ac9da1b012987b285 432 Pfam PF00480 ROK family 90 405 1.4E-49 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_18720 de724294e33a750ac9da1b012987b285 432 ProSitePatterns PS01125 ROK family signature. 223 250 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_18720 de724294e33a750ac9da1b012987b285 432 Gene3D G3DSA:3.30.420.40 210 390 2.5E-87 T 14-10-2018 A4R43_18720 de724294e33a750ac9da1b012987b285 432 Gene3D G3DSA:1.10.10.10 15 79 8.3E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18720 de724294e33a750ac9da1b012987b285 432 Gene3D G3DSA:3.30.420.40 91 400 2.5E-87 T 14-10-2018 A4R43_18720 de724294e33a750ac9da1b012987b285 432 SUPERFAMILY SSF53067 84 406 5.76E-52 T 14-10-2018 A4R43_18720 de724294e33a750ac9da1b012987b285 432 SUPERFAMILY SSF46785 20 76 6.82E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40155 7a77d25a8e478e0c43639a26aaa4d2b1 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 1.4E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_40155 7a77d25a8e478e0c43639a26aaa4d2b1 214 Pfam PF07729 FCD domain 81 204 4.3E-21 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_40155 7a77d25a8e478e0c43639a26aaa4d2b1 214 Gene3D G3DSA:1.20.120.530 74 209 1.2E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_40155 7a77d25a8e478e0c43639a26aaa4d2b1 214 SMART SM00895 80 205 7.9E-18 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_40155 7a77d25a8e478e0c43639a26aaa4d2b1 214 Gene3D G3DSA:1.10.10.10 2 70 1.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40155 7a77d25a8e478e0c43639a26aaa4d2b1 214 SUPERFAMILY SSF48008 77 209 1.1E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_40155 7a77d25a8e478e0c43639a26aaa4d2b1 214 SMART SM00345 12 70 5.5E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_40155 7a77d25a8e478e0c43639a26aaa4d2b1 214 SUPERFAMILY SSF46785 5 74 5.96E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02810 c042887be27ae888e08a669fbebc3d70 191 SUPERFAMILY SSF47413 12 74 1.26E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_02810 c042887be27ae888e08a669fbebc3d70 191 Gene3D G3DSA:1.10.260.40 1 76 1.0E-18 T 14-10-2018 A4R43_02810 c042887be27ae888e08a669fbebc3d70 191 SMART SM00530 15 70 1.1E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_02810 c042887be27ae888e08a669fbebc3d70 191 SUPERFAMILY SSF51182 21 177 1.49E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_02810 c042887be27ae888e08a669fbebc3d70 191 Pfam PF07883 Cupin domain 115 174 1.2E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_02810 c042887be27ae888e08a669fbebc3d70 191 Pfam PF01381 Helix-turn-helix 16 70 1.3E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_02810 c042887be27ae888e08a669fbebc3d70 191 Gene3D G3DSA:2.60.120.10 77 181 2.2E-10 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_09680 0eb465e1924134eec72344922efa6d4c 262 SMART SM00346 17 106 3.3E-22 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_09680 0eb465e1924134eec72344922efa6d4c 262 SUPERFAMILY SSF55781 74 256 3.34E-38 T 14-10-2018 A4R43_09680 0eb465e1924134eec72344922efa6d4c 262 Pfam PF09339 IclR helix-turn-helix domain 19 69 1.0E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_09680 0eb465e1924134eec72344922efa6d4c 262 Gene3D G3DSA:1.10.10.10 15 90 2.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09680 0eb465e1924134eec72344922efa6d4c 262 Gene3D G3DSA:3.30.450.40 94 262 1.5E-40 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_09680 0eb465e1924134eec72344922efa6d4c 262 SUPERFAMILY SSF46785 18 87 1.15E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09680 0eb465e1924134eec72344922efa6d4c 262 Pfam PF01614 Bacterial transcriptional regulator 135 252 8.4E-30 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_33625 c835e6273db3b4a1943fb9d74c2fb500 392 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 298 1.7E-69 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33625 c835e6273db3b4a1943fb9d74c2fb500 392 Pfam PF02470 MlaD protein 38 111 1.9E-12 T 14-10-2018 IPR003399 Mce/MlaD A4R43_07870 edd36d1315da9394bd08f9d76ac8a11a 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_07870 edd36d1315da9394bd08f9d76ac8a11a 485 Gene3D G3DSA:3.40.309.10 258 445 7.3E-151 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_07870 edd36d1315da9394bd08f9d76ac8a11a 485 SUPERFAMILY SSF53720 15 476 2.23E-146 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_07870 edd36d1315da9394bd08f9d76ac8a11a 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_07870 edd36d1315da9394bd08f9d76ac8a11a 485 Gene3D G3DSA:3.40.605.10 24 472 7.3E-151 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_07870 edd36d1315da9394bd08f9d76ac8a11a 485 Pfam PF00171 Aldehyde dehydrogenase family 19 473 1.5E-150 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 301 1.7E-23 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 Gene3D G3DSA:3.40.50.1370 136 282 6.4E-87 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 1.9E-30 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 1.9E-30 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 1.9E-30 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.9E-30 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 1.9E-30 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.9E-30 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 Gene3D G3DSA:3.40.50.1370 10 298 6.4E-87 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 303 7.1E-85 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 SUPERFAMILY SSF53671 2 304 9.17E-92 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 3.0E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 3.0E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 3.0E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 3.0E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 305 38.537 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04715 fd26161de5c8ef7bfd16c4df036b055f 312 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 148 2.1E-37 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A4R43_14990 97a44c61bbe82cc9c6af9e9677eb8edc 819 Gene3D G3DSA:3.40.50.300 398 603 1.3E-13 T 14-10-2018 A4R43_14990 97a44c61bbe82cc9c6af9e9677eb8edc 819 Gene3D G3DSA:3.40.50.300 611 768 7.1E-15 T 14-10-2018 A4R43_14990 97a44c61bbe82cc9c6af9e9677eb8edc 819 Pfam PF01935 Domain of unknown function DUF87 412 484 3.2E-7 T 14-10-2018 IPR002789 Helicase HerA, central domain A4R43_14990 97a44c61bbe82cc9c6af9e9677eb8edc 819 SUPERFAMILY SSF52540 389 756 2.66E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14990 97a44c61bbe82cc9c6af9e9677eb8edc 819 Pfam PF12696 TraM recognition site of TraD and TraG 670 738 8.4E-5 T 14-10-2018 IPR032689 TraD/TraG, TraM recognition site A4R43_06795 83cee61b09f04a5593a4d858dcf1bcb1 92 Pfam PF08980 Domain of unknown function (DUF1883) 5 76 9.3E-21 T 14-10-2018 IPR015073 Domain of unknown function DUF1883 A4R43_06795 83cee61b09f04a5593a4d858dcf1bcb1 92 SUPERFAMILY SSF141099 5 78 1.7E-19 T 14-10-2018 IPR036488 Atu1913-like superfamily A4R43_06795 83cee61b09f04a5593a4d858dcf1bcb1 92 Gene3D G3DSA:4.10.1210.10 1 87 1.8E-25 T 14-10-2018 IPR036488 Atu1913-like superfamily A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 1.4E-36 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 Gene3D G3DSA:1.20.140.10 237 383 4.4E-52 T 14-10-2018 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 Gene3D G3DSA:1.10.540.10 1 121 1.5E-40 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 2.4E-51 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 SUPERFAMILY SSF47203 232 382 4.03E-53 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 Gene3D G3DSA:2.40.110.10 123 236 2.1E-36 T 14-10-2018 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 SUPERFAMILY SSF56645 2 244 1.03E-79 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_37215 c813779f8620278c3f9ccb9c299f0c60 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 221 8.6E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_11765 027559e004517298af4aad77adfe7ebf 155 Gene3D G3DSA:3.10.450.50 11 155 3.6E-73 T 14-10-2018 A4R43_11765 027559e004517298af4aad77adfe7ebf 155 Pfam PF07080 Protein of unknown function (DUF1348) 8 136 3.6E-62 T 14-10-2018 IPR009783 Protein of unknown function DUF1348 A4R43_11765 027559e004517298af4aad77adfe7ebf 155 SUPERFAMILY SSF54427 2 155 1.94E-77 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_11625 ddba83dd35eaf65594ca299bfefb6857 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 2.2E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11625 ddba83dd35eaf65594ca299bfefb6857 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 2.2E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11625 ddba83dd35eaf65594ca299bfefb6857 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 1.4E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11625 ddba83dd35eaf65594ca299bfefb6857 224 SUPERFAMILY SSF46689 2 75 4.73E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11625 ddba83dd35eaf65594ca299bfefb6857 224 Pfam PF13305 WHG domain 84 156 2.1E-7 T 14-10-2018 IPR025996 WHG domain A4R43_11625 ddba83dd35eaf65594ca299bfefb6857 224 SUPERFAMILY SSF48498 77 176 1.63E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11625 ddba83dd35eaf65594ca299bfefb6857 224 Gene3D G3DSA:1.10.357.10 1 178 2.8E-32 T 14-10-2018 A4R43_41715 32356791d607b0d0d66b18555fd9ba17 228 Gene3D G3DSA:2.60.40.10 126 228 4.3E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_41715 32356791d607b0d0d66b18555fd9ba17 228 Gene3D G3DSA:2.60.40.10 20 103 3.8E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_41715 32356791d607b0d0d66b18555fd9ba17 228 SUPERFAMILY SSF49265 24 225 8.49E-10 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 SMART SM00387 346 459 2.5E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 Pfam PF00672 HAMP domain 172 222 3.6E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 SMART SM00388 234 297 4.3E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 Gene3D G3DSA:1.20.1480.50 133 230 2.4E-10 T 14-10-2018 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 SMART SM00304 172 226 4.4E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 Gene3D G3DSA:3.30.565.10 301 457 8.7E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 SUPERFAMILY SSF47384 220 298 2.55E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 457 4.2E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 8.4E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 8.4E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 8.4E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 8.4E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 297 9.2E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 Gene3D G3DSA:1.10.287.130 231 297 1.3E-17 T 14-10-2018 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 SUPERFAMILY SSF158472 175 222 1.07E-6 T 14-10-2018 A4R43_21140 e4f26d0dbc28b50791d4af4711c2af56 459 SUPERFAMILY SSF55874 286 456 1.44E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 6.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 6.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 6.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 SMART SM00448 7 117 3.2E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 SUPERFAMILY SSF46894 143 209 4.42E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 SUPERFAMILY SSF52172 7 136 8.25E-17 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 1.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 SMART SM00421 147 204 2.0E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 Gene3D G3DSA:3.40.50.12740 7 210 1.6E-40 T 14-10-2018 A4R43_17470 d1e8251f4eb0f803d727d673cd416dd4 213 Pfam PF00072 Response regulator receiver domain 11 117 6.0E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_11490 b296389e5d4d8a15727dc7da2e7fd802 446 Pfam PF13416 Bacterial extracellular solute-binding protein 71 373 5.7E-32 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_11490 b296389e5d4d8a15727dc7da2e7fd802 446 Gene3D G3DSA:3.40.190.10 47 399 9.2E-64 T 14-10-2018 A4R43_11490 b296389e5d4d8a15727dc7da2e7fd802 446 SUPERFAMILY SSF53850 17 441 2.61E-62 T 14-10-2018 A4R43_11490 b296389e5d4d8a15727dc7da2e7fd802 446 Gene3D G3DSA:3.40.190.10 158 418 9.2E-64 T 14-10-2018 A4R43_24085 c58ea7564e33d891d96876da674c933a 274 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 17 269 5.0E-79 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A4R43_24085 c58ea7564e33d891d96876da674c933a 274 Pfam PF01026 TatD related DNase 18 268 5.2E-68 T 14-10-2018 IPR001130 TatD family GO:0016788 A4R43_24085 c58ea7564e33d891d96876da674c933a 274 PIRSF PIRSF005902 7 273 1.9E-70 T 14-10-2018 IPR001130 TatD family GO:0016788 A4R43_24085 c58ea7564e33d891d96876da674c933a 274 SUPERFAMILY SSF51556 18 270 6.1E-77 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_24085 c58ea7564e33d891d96876da674c933a 274 Gene3D G3DSA:3.20.20.140 11 270 6.5E-80 T 14-10-2018 A4R43_33335 d52b5f4010417571da7702a67efce32a 368 Gene3D G3DSA:3.40.640.10 1 239 1.3E-83 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_33335 d52b5f4010417571da7702a67efce32a 368 PIRSF PIRSF000390 5 368 2.4E-104 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_33335 d52b5f4010417571da7702a67efce32a 368 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 19 363 8.0E-114 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_33335 d52b5f4010417571da7702a67efce32a 368 SUPERFAMILY SSF53383 15 367 1.33E-103 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_33335 d52b5f4010417571da7702a67efce32a 368 Gene3D G3DSA:3.90.1150.10 240 368 3.3E-39 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_23610 677e03fa88d18e4b8b1a3d21e42c5e8c 463 SUPERFAMILY SSF88723 32 168 1.37E-9 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_23610 677e03fa88d18e4b8b1a3d21e42c5e8c 463 Pfam PF02562 PhoH-like protein 255 459 2.3E-52 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 A4R43_23610 677e03fa88d18e4b8b1a3d21e42c5e8c 463 SMART SM00670 33 160 1.0E-18 T 14-10-2018 IPR002716 PIN domain A4R43_23610 677e03fa88d18e4b8b1a3d21e42c5e8c 463 Gene3D G3DSA:3.40.50.1010 29 175 1.5E-17 T 14-10-2018 A4R43_23610 677e03fa88d18e4b8b1a3d21e42c5e8c 463 Pfam PF13638 PIN domain 35 173 6.1E-28 T 14-10-2018 IPR002716 PIN domain A4R43_23610 677e03fa88d18e4b8b1a3d21e42c5e8c 463 SUPERFAMILY SSF52540 253 415 1.08E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23610 677e03fa88d18e4b8b1a3d21e42c5e8c 463 Gene3D G3DSA:3.40.50.300 253 460 4.1E-52 T 14-10-2018 A4R43_26765 00350c16e2478106e672dc01c6fdc78b 168 Gene3D G3DSA:2.40.40.20 1 125 6.7E-54 T 14-10-2018 A4R43_26765 00350c16e2478106e672dc01c6fdc78b 168 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 122 7.2E-52 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4R43_26765 00350c16e2478106e672dc01c6fdc78b 168 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 93 5.0E-29 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4R43_26765 00350c16e2478106e672dc01c6fdc78b 168 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 73.884 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4R43_26765 00350c16e2478106e672dc01c6fdc78b 168 PIRSF PIRSF006246 130 160 48.0 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4R43_26765 00350c16e2478106e672dc01c6fdc78b 168 PIRSF PIRSF006246 1 130 9.1E-53 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4R43_26765 00350c16e2478106e672dc01c6fdc78b 168 Pfam PF02261 Aspartate decarboxylase 1 114 1.9E-52 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4R43_26765 00350c16e2478106e672dc01c6fdc78b 168 SUPERFAMILY SSF50692 1 114 3.15E-49 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 Gene3D G3DSA:1.10.540.10 34 153 1.7E-5 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 Gene3D G3DSA:1.20.140.10 295 463 2.2E-30 T 14-10-2018 A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 457 1.4E-12 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 SUPERFAMILY SSF47203 295 481 3.22E-29 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 SUPERFAMILY SSF56645 57 297 9.82E-42 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 477 610 8.1E-32 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 25 1.4E-7 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 Gene3D G3DSA:2.40.110.10 160 294 5.8E-25 T 14-10-2018 A4R43_31225 e27aba91a04bd5acd38d26cc8d092b4b 614 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 275 6.9E-17 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_35875 e12ffebd6eaaa35f60dd5257cc2d778b 374 SUPERFAMILY SSF55486 156 338 8.38E-17 T 14-10-2018 A4R43_35875 e12ffebd6eaaa35f60dd5257cc2d778b 374 Pfam PF11350 Protein of unknown function (DUF3152) 158 369 6.2E-71 T 14-10-2018 IPR022603 Domain of unknown function DUF3152 A4R43_31055 3c03be0326a7df34e0600a0bacae43b1 315 Pfam PF12802 MarR family 44 100 3.8E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31055 3c03be0326a7df34e0600a0bacae43b1 315 SMART SM00347 36 136 9.6E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31055 3c03be0326a7df34e0600a0bacae43b1 315 Gene3D G3DSA:1.10.10.10 12 149 7.8E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31055 3c03be0326a7df34e0600a0bacae43b1 315 SUPERFAMILY SSF55729 156 302 3.6E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_31055 3c03be0326a7df34e0600a0bacae43b1 315 Gene3D G3DSA:3.40.630.30 152 299 2.6E-20 T 14-10-2018 A4R43_31055 3c03be0326a7df34e0600a0bacae43b1 315 SUPERFAMILY SSF46785 19 151 2.5E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31055 3c03be0326a7df34e0600a0bacae43b1 315 Pfam PF00583 Acetyltransferase (GNAT) family 199 291 3.4E-12 T 14-10-2018 IPR000182 GNAT domain A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 Gene3D G3DSA:1.10.720.90 2 55 1.6E-17 T 14-10-2018 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.5E-38 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.5E-38 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.5E-38 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 1.0E-20 T 14-10-2018 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 SUPERFAMILY SSF74731 3 116 2.88E-44 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 Gene3D G3DSA:1.10.1900.20 56 119 2.0E-27 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 Pfam PF00453 Ribosomal protein L20 3 109 1.0E-43 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 6.3E-43 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14360 2049a549514f51c7912ebeba2ba75e1c 126 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.107 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_10365 f791e34bed144b7399f3f103d032d8c9 277 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 85 106 4.2E-32 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A4R43_10365 f791e34bed144b7399f3f103d032d8c9 277 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 126 148 4.2E-32 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A4R43_10365 f791e34bed144b7399f3f103d032d8c9 277 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 229 247 4.2E-32 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A4R43_10365 f791e34bed144b7399f3f103d032d8c9 277 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 187 204 4.2E-32 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A4R43_10365 f791e34bed144b7399f3f103d032d8c9 277 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 149 169 4.2E-32 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A4R43_10365 f791e34bed144b7399f3f103d032d8c9 277 SUPERFAMILY SSF63829 12 273 6.05E-57 T 14-10-2018 A4R43_10365 f791e34bed144b7399f3f103d032d8c9 277 Gene3D G3DSA:2.120.10.30 1 276 7.3E-86 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_10365 f791e34bed144b7399f3f103d032d8c9 277 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 247 2.3E-71 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region A4R43_03650 edd9fb1541280a69a6dae82fe09d8165 265 Gene3D G3DSA:1.10.10.10 11 83 6.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03650 edd9fb1541280a69a6dae82fe09d8165 265 SMART SM00346 14 105 9.3E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_03650 edd9fb1541280a69a6dae82fe09d8165 265 SUPERFAMILY SSF46785 14 88 4.85E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03650 edd9fb1541280a69a6dae82fe09d8165 265 Gene3D G3DSA:3.30.450.40 84 262 2.3E-47 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_03650 edd9fb1541280a69a6dae82fe09d8165 265 Pfam PF01614 Bacterial transcriptional regulator 137 255 8.9E-28 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_03650 edd9fb1541280a69a6dae82fe09d8165 265 Pfam PF09339 IclR helix-turn-helix domain 16 67 7.4E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_03650 edd9fb1541280a69a6dae82fe09d8165 265 SUPERFAMILY SSF55781 86 256 2.81E-42 T 14-10-2018 A4R43_40585 fdbdc20c64d57b8f1a912e110f17a737 217 SMART SM00020 27 211 1.4E-8 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_40585 fdbdc20c64d57b8f1a912e110f17a737 217 SUPERFAMILY SSF50494 10 215 1.84E-34 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_40585 fdbdc20c64d57b8f1a912e110f17a737 217 Gene3D G3DSA:2.40.10.10 116 204 1.7E-5 T 14-10-2018 A4R43_40585 fdbdc20c64d57b8f1a912e110f17a737 217 Gene3D G3DSA:2.40.10.10 32 115 1.6E-16 T 14-10-2018 A4R43_40585 fdbdc20c64d57b8f1a912e110f17a737 217 Pfam PF00089 Trypsin 34 202 8.8E-26 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_40585 fdbdc20c64d57b8f1a912e110f17a737 217 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 99 113 1.5E-9 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_40585 fdbdc20c64d57b8f1a912e110f17a737 217 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 52 67 1.5E-9 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_40585 fdbdc20c64d57b8f1a912e110f17a737 217 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 169 181 1.5E-9 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_14535 d847c8547c035b8894f35224002f4f5b 350 SUPERFAMILY SSF51735 118 257 4.87E-11 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_14535 d847c8547c035b8894f35224002f4f5b 350 SUPERFAMILY SSF81324 22 126 1.31E-17 T 14-10-2018 A4R43_14535 d847c8547c035b8894f35224002f4f5b 350 Pfam PF07885 Ion channel 24 102 8.8E-11 T 14-10-2018 IPR013099 Potassium channel domain A4R43_14535 d847c8547c035b8894f35224002f4f5b 350 Gene3D G3DSA:1.10.287.70 5 99 8.6E-15 T 14-10-2018 A4R43_14535 d847c8547c035b8894f35224002f4f5b 350 Gene3D G3DSA:3.40.50.720 100 231 4.9E-19 T 14-10-2018 A4R43_14535 d847c8547c035b8894f35224002f4f5b 350 Pfam PF02254 TrkA-N domain 131 229 1.1E-8 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 PIRSF PIRSF000185 5 389 5.7E-79 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 59 73 3.9E-6 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 190 210 3.9E-6 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 Gene3D G3DSA:3.40.50.10860 11 123 1.2E-22 T 14-10-2018 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 Gene3D G3DSA:3.40.50.720 157 390 9.0E-45 T 14-10-2018 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 67 80 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 SMART SM00839 162 390 3.8E-46 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 22 114 8.6E-14 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 157 324 2.3E-34 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 SUPERFAMILY SSF53223 13 122 1.73E-24 T 14-10-2018 A4R43_11160 24c9fa299e629b0d3672e053ce27ffbd 397 SUPERFAMILY SSF51735 157 378 8.05E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 Pfam PF01197 Ribosomal protein L31 1 79 3.6E-31 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.8E-21 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.6E-16 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.6E-16 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.6E-16 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.987 T 14-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 Gene3D G3DSA:2.30.170.50 1 83 3.9E-26 T 14-10-2018 A4R43_11315 9fcb2653242879b5cbe7609c5fed5e10 85 SUPERFAMILY SSF143800 1 80 2.39E-22 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_23540 5b536bd12ac8022272ed5002100f2eb1 290 SUPERFAMILY SSF103481 46 148 1.96E-12 T 14-10-2018 A4R43_23540 5b536bd12ac8022272ed5002100f2eb1 290 Pfam PF00892 EamA-like transporter family 153 284 3.5E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_23540 5b536bd12ac8022272ed5002100f2eb1 290 Pfam PF00892 EamA-like transporter family 13 145 5.6E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_23540 5b536bd12ac8022272ed5002100f2eb1 290 SUPERFAMILY SSF103481 196 288 1.44E-11 T 14-10-2018 A4R43_32060 d9704aa8dfcc11e1f3f77a05e500410c 102 Gene3D G3DSA:2.60.40.1120 26 101 4.4E-5 T 14-10-2018 A4R43_32060 d9704aa8dfcc11e1f3f77a05e500410c 102 SUPERFAMILY SSF49478 27 79 2.9E-7 T 14-10-2018 A4R43_32060 d9704aa8dfcc11e1f3f77a05e500410c 102 Pfam PF07210 Protein of unknown function (DUF1416) 6 101 2.7E-39 T 14-10-2018 IPR010814 Protein of unknown function DUF1416 A4R43_29625 1f1031485adc050f84512e19f81745d7 160 SUPERFAMILY SSF55811 20 147 2.71E-21 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_29625 1f1031485adc050f84512e19f81745d7 160 Pfam PF00293 NUDIX domain 21 144 3.5E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_29625 1f1031485adc050f84512e19f81745d7 160 Gene3D G3DSA:3.90.79.10 11 155 1.0E-20 T 14-10-2018 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SMART SM00028 850 883 68.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SMART SM00028 770 803 16.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SMART SM00028 810 843 65.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 78 3.5E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SUPERFAMILY SSF48452 716 881 6.32E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Gene3D G3DSA:3.40.50.300 238 393 2.1E-26 T 14-10-2018 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Gene3D G3DSA:1.25.40.10 813 896 4.2E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Pfam PF03704 Bacterial transcriptional activator domain 94 226 6.0E-29 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Pfam PF13424 Tetratricopeptide repeat 729 798 4.3E-10 T 14-10-2018 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SUPERFAMILY SSF46894 4 89 4.54E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Gene3D G3DSA:1.25.40.10 92 237 1.6E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SUPERFAMILY SSF48452 94 244 7.28E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 PRINTS PR00364 Disease resistance protein signature 273 288 4.6E-7 T 14-10-2018 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 PRINTS PR00364 Disease resistance protein signature 351 365 4.6E-7 T 14-10-2018 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 PRINTS PR00364 Disease resistance protein signature 438 452 4.6E-7 T 14-10-2018 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Gene3D G3DSA:1.10.10.10 1 91 4.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Gene3D G3DSA:1.25.40.10 646 809 1.1E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SUPERFAMILY SSF52540 239 508 4.55E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 Pfam PF00931 NB-ARC domain 260 450 1.7E-7 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SMART SM00862 17 89 7.8E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03405 edc8afd51ac81dde1fd31707ff03ffd0 898 SMART SM01043 96 226 6.9E-33 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_17725 71e5385138ea5a821eec5580a7235a7e 644 PIRSF PIRSF001589 1 637 1.2E-165 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_17725 71e5385138ea5a821eec5580a7235a7e 644 SUPERFAMILY SSF52402 247 619 2.65E-78 T 14-10-2018 A4R43_17725 71e5385138ea5a821eec5580a7235a7e 644 Gene3D G3DSA:3.60.20.10 4 197 6.0E-53 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_17725 71e5385138ea5a821eec5580a7235a7e 644 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 561 1.5E-133 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_17725 71e5385138ea5a821eec5580a7235a7e 644 Pfam PF13537 Glutamine amidotransferase domain 50 172 2.2E-35 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4R43_17725 71e5385138ea5a821eec5580a7235a7e 644 Pfam PF00733 Asparagine synthase 253 623 6.6E-98 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4R43_17725 71e5385138ea5a821eec5580a7235a7e 644 SUPERFAMILY SSF56235 2 230 1.97E-52 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_00075 a41db9e15b42f6da2b0319df0b17843a 124 Gene3D G3DSA:3.10.450.50 2 119 1.4E-16 T 14-10-2018 A4R43_00075 a41db9e15b42f6da2b0319df0b17843a 124 SUPERFAMILY SSF54427 9 106 1.44E-7 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_31100 67b77799ce99ca8afead874aa258bb75 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 2.4E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31100 67b77799ce99ca8afead874aa258bb75 218 SUPERFAMILY SSF46689 10 91 2.98E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31100 67b77799ce99ca8afead874aa258bb75 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31100 67b77799ce99ca8afead874aa258bb75 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31100 67b77799ce99ca8afead874aa258bb75 218 Gene3D G3DSA:1.10.357.10 6 209 9.9E-56 T 14-10-2018 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 SUPERFAMILY SSF55681 6 370 5.77E-122 T 14-10-2018 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 5.6E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 138 150 5.6E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 318 330 5.6E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 191 208 5.6E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 5.6E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 159 176 5.6E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 208 218 5.6E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 Gene3D G3DSA:3.40.50.800 365 459 7.0E-34 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 SUPERFAMILY SSF52954 354 458 1.51E-34 T 14-10-2018 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 225 3.3E-80 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 459 49.87 T 14-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 302 3.2E-8 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_39760 5e08f6616a9b7e92e527bae5f21c83d1 461 Pfam PF03129 Anticodon binding domain 367 456 3.0E-25 T 14-10-2018 IPR004154 Anticodon-binding A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 SUPERFAMILY SSF52518 1 169 5.47E-40 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 Gene3D G3DSA:3.40.50.970 339 535 5.3E-59 T 14-10-2018 A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 Gene3D G3DSA:3.40.50.970 1 167 1.7E-46 T 14-10-2018 A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 SUPERFAMILY SSF52518 344 522 5.9E-56 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 183 278 3.9E-21 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 Gene3D G3DSA:3.40.50.1220 181 336 5.4E-29 T 14-10-2018 A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 161 1.7E-41 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 404 423 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 SUPERFAMILY SSF52467 182 350 9.24E-29 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_32420 fdd929a8bb13622a4d43d7033342404c 536 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 368 513 4.8E-38 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_07495 7620fe8a0d97605f97a07e541ebf8780 320 Pfam PF00534 Glycosyl transferases group 1 204 296 1.0E-10 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_07495 7620fe8a0d97605f97a07e541ebf8780 320 SUPERFAMILY SSF53756 55 317 1.3E-21 T 14-10-2018 A4R43_07495 7620fe8a0d97605f97a07e541ebf8780 320 Gene3D G3DSA:3.40.50.2000 177 298 9.4E-16 T 14-10-2018 A4R43_18535 0883306374121aa7db82a3809fe98236 429 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_18535 0883306374121aa7db82a3809fe98236 429 SUPERFAMILY SSF53383 6 424 3.76E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_18535 0883306374121aa7db82a3809fe98236 429 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 423 2.4E-181 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 A4R43_18535 0883306374121aa7db82a3809fe98236 429 PIRSF PIRSF001434 1 427 4.5E-125 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_18535 0883306374121aa7db82a3809fe98236 429 Gene3D G3DSA:3.40.640.10 7 288 1.1E-99 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_18535 0883306374121aa7db82a3809fe98236 429 Gene3D G3DSA:3.90.1150.10 292 429 5.8E-49 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_18535 0883306374121aa7db82a3809fe98236 429 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 423 2.6E-131 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_02405 18d1814dbaccf657fdaa9cc3c950cd1a 319 SUPERFAMILY SSF53613 1 309 1.09E-77 T 14-10-2018 IPR029056 Ribokinase-like A4R43_02405 18d1814dbaccf657fdaa9cc3c950cd1a 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 257 270 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_02405 18d1814dbaccf657fdaa9cc3c950cd1a 319 Gene3D G3DSA:3.40.1190.20 1 316 4.8E-87 T 14-10-2018 IPR029056 Ribokinase-like A4R43_02405 18d1814dbaccf657fdaa9cc3c950cd1a 319 Pfam PF00294 pfkB family carbohydrate kinase 4 304 1.9E-54 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_15135 78edbede0fdd4a6f10db234bc3ca82a9 141 Gene3D G3DSA:2.30.31.20 2 136 4.3E-45 T 14-10-2018 IPR038658 Sporulation-specific cell division protein SsgB superfamily A4R43_15135 78edbede0fdd4a6f10db234bc3ca82a9 141 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 26 122 9.7E-34 T 14-10-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4R43_31345 ffd91fb1c7a649706c416d8f5e0327b3 157 SUPERFAMILY SSF69118 17 154 4.58E-39 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_31345 ffd91fb1c7a649706c416d8f5e0327b3 157 Gene3D G3DSA:1.20.1290.10 3 149 1.5E-43 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_31345 ffd91fb1c7a649706c416d8f5e0327b3 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 80 1.4E-18 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_31345 ffd91fb1c7a649706c416d8f5e0327b3 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 29 96 3.9E-19 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 SUPERFAMILY SSF56003 63 255 1.65E-26 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 SMART SM01008 225 304 1.2E-4 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 Gene3D G3DSA:3.90.1170.50 197 299 9.4E-8 T 14-10-2018 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 PIRSF PIRSF036389 3 741 1.2E-151 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 SUPERFAMILY SSF56003 327 734 3.84E-78 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 Gene3D G3DSA:3.30.365.10 325 447 9.5E-20 T 14-10-2018 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 Gene3D G3DSA:3.30.365.10 529 740 1.8E-35 T 14-10-2018 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 66 216 3.5E-15 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 623 679 6.3E-7 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 332 564 7.8E-19 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 Gene3D G3DSA:3.30.365.10 343 436 9.5E-20 T 14-10-2018 A4R43_01340 3d0c0dd543f2b70da23974cf6935301b 762 Gene3D G3DSA:3.30.365.10 59 196 1.8E-22 T 14-10-2018 A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 0.0047 T 14-10-2018 A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 Gene3D G3DSA:3.40.50.720 1 246 2.5E-74 T 14-10-2018 A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 8.1E-53 T 14-10-2018 A4R43_34300 1363ca4f527e75e3d8a177b53b07cea7 246 SUPERFAMILY SSF51735 2 245 1.6E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05665 4087a142c09fae766ba7ff67d7729cb8 254 Pfam PF12679 ABC-2 family transporter protein 52 253 1.5E-15 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A4R43_09700 3349cad271a9ca9f70bf71417b51c531 619 SUPERFAMILY SSF49899 359 615 7.64E-21 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_09700 3349cad271a9ca9f70bf71417b51c531 619 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 462 615 1.3E-14 T 14-10-2018 A4R43_09700 3349cad271a9ca9f70bf71417b51c531 619 Pfam PF00149 Calcineurin-like phosphoesterase 53 233 8.3E-6 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_09700 3349cad271a9ca9f70bf71417b51c531 619 Gene3D G3DSA:2.60.120.200 387 618 5.1E-15 T 14-10-2018 A4R43_09700 3349cad271a9ca9f70bf71417b51c531 619 SMART SM00560 462 614 0.0087 T 14-10-2018 IPR006558 LamG-like jellyroll fold A4R43_09700 3349cad271a9ca9f70bf71417b51c531 619 SUPERFAMILY SSF56300 53 296 1.07E-18 T 14-10-2018 A4R43_09700 3349cad271a9ca9f70bf71417b51c531 619 Gene3D G3DSA:3.60.21.10 36 280 3.9E-10 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_36225 f5bd6e0580572db5ebc2ff36026fdd90 317 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 111 125 8.7E-13 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_36225 f5bd6e0580572db5ebc2ff36026fdd90 317 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 8.7E-13 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_36225 f5bd6e0580572db5ebc2ff36026fdd90 317 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 8.7E-13 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_36225 f5bd6e0580572db5ebc2ff36026fdd90 317 Gene3D G3DSA:3.40.50.1820 1 317 7.3E-96 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_36225 f5bd6e0580572db5ebc2ff36026fdd90 317 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 316 6.6E-110 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 A4R43_36225 f5bd6e0580572db5ebc2ff36026fdd90 317 SUPERFAMILY SSF53474 2 300 6.95E-64 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_36225 f5bd6e0580572db5ebc2ff36026fdd90 317 PIRSF PIRSF006431 1 317 1.1E-124 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 A4R43_36225 f5bd6e0580572db5ebc2ff36026fdd90 317 Pfam PF00561 alpha/beta hydrolase fold 35 303 4.5E-27 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22395 d394f617e2b02102282c24fad7243722 217 Pfam PF01300 Telomere recombination 24 197 2.8E-45 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 A4R43_22395 d394f617e2b02102282c24fad7243722 217 Gene3D G3DSA:3.90.870.10 2 212 1.3E-64 T 14-10-2018 A4R43_22395 d394f617e2b02102282c24fad7243722 217 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 207 1.7E-60 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 A4R43_22395 d394f617e2b02102282c24fad7243722 217 SUPERFAMILY SSF55821 4 208 2.96E-57 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A4R43_15450 40c0f12c04fc88cdd10b1bba7ed17bea 259 Gene3D G3DSA:3.40.190.10 117 219 5.1E-60 T 14-10-2018 A4R43_15450 40c0f12c04fc88cdd10b1bba7ed17bea 259 Gene3D G3DSA:3.40.190.10 40 256 5.1E-60 T 14-10-2018 A4R43_15450 40c0f12c04fc88cdd10b1bba7ed17bea 259 PIRSF PIRSF004846 3 259 3.9E-66 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 A4R43_15450 40c0f12c04fc88cdd10b1bba7ed17bea 259 SUPERFAMILY SSF53850 38 258 6.08E-53 T 14-10-2018 A4R43_15450 40c0f12c04fc88cdd10b1bba7ed17bea 259 Pfam PF13531 Bacterial extracellular solute-binding protein 39 256 8.7E-41 T 14-10-2018 A4R43_15450 40c0f12c04fc88cdd10b1bba7ed17bea 259 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 44 253 3.4E-39 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PIRSF PIRSF001480 1 406 1.3E-91 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 391 2.2E-67 T 14-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 Pfam PF01238 Phosphomannose isomerase type I 4 365 4.4E-62 T 14-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 Gene3D G3DSA:2.60.120.10 310 391 8.0E-127 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_23270 940092066b3b535494aa704d14bf7bde 407 SUPERFAMILY SSF51182 3 390 6.76E-88 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_23270 940092066b3b535494aa704d14bf7bde 407 Gene3D G3DSA:2.60.120.10 6 284 8.0E-127 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_23270 940092066b3b535494aa704d14bf7bde 407 Gene3D G3DSA:1.10.441.10 151 309 8.0E-127 T 14-10-2018 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 1.2E-57 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PRINTS PR00714 Phosphomannose isomerase type I signature 127 150 1.2E-57 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 1.2E-57 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 1.2E-57 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 1.2E-57 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PRINTS PR00714 Phosphomannose isomerase type I signature 82 103 1.2E-57 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 1.2E-57 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_23270 940092066b3b535494aa704d14bf7bde 407 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 1.2E-57 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4R43_09545 dd650467b2376e55197731bcfe431a57 548 SUPERFAMILY SSF53850 62 533 4.25E-96 T 14-10-2018 A4R43_09545 dd650467b2376e55197731bcfe431a57 548 Gene3D G3DSA:3.40.190.10 215 529 1.5E-93 T 14-10-2018 A4R43_09545 dd650467b2376e55197731bcfe431a57 548 Gene3D G3DSA:3.10.105.10 289 520 1.5E-93 T 14-10-2018 A4R43_09545 dd650467b2376e55197731bcfe431a57 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 461 3.2E-69 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_09545 dd650467b2376e55197731bcfe431a57 548 Gene3D G3DSA:3.90.76.10 64 214 1.5E-93 T 14-10-2018 A4R43_09545 dd650467b2376e55197731bcfe431a57 548 PIRSF PIRSF002741 11 545 1.8E-73 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_01845 2a990e58c485eb80f607e53ae741a52b 386 Gene3D G3DSA:3.40.710.30 6 383 4.0E-111 T 14-10-2018 A4R43_01845 2a990e58c485eb80f607e53ae741a52b 386 Pfam PF00144 Beta-lactamase 23 375 2.6E-48 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_01845 2a990e58c485eb80f607e53ae741a52b 386 SUPERFAMILY SSF56601 11 375 7.51E-53 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_03005 fd555afcd6c305c3c861f87b7c60d0f3 455 Pfam PF07690 Major Facilitator Superfamily 25 407 4.7E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_03005 fd555afcd6c305c3c861f87b7c60d0f3 455 SUPERFAMILY SSF103473 10 446 5.62E-60 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_03005 fd555afcd6c305c3c861f87b7c60d0f3 455 Gene3D G3DSA:1.20.1720.10 18 249 2.8E-38 T 14-10-2018 A4R43_03005 fd555afcd6c305c3c861f87b7c60d0f3 455 PRINTS PR01035 Tetracycline resistance protein signature 30 46 6.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_03005 fd555afcd6c305c3c861f87b7c60d0f3 455 PRINTS PR01035 Tetracycline resistance protein signature 308 328 6.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_03005 fd555afcd6c305c3c861f87b7c60d0f3 455 PRINTS PR01035 Tetracycline resistance protein signature 143 165 6.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_03005 fd555afcd6c305c3c861f87b7c60d0f3 455 PRINTS PR01035 Tetracycline resistance protein signature 60 79 6.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_03005 fd555afcd6c305c3c861f87b7c60d0f3 455 Gene3D G3DSA:1.20.1250.20 262 449 1.3E-12 T 14-10-2018 A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 5 426 24.891 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 Pfam PF03129 Anticodon binding domain 337 425 1.3E-16 T 14-10-2018 IPR004154 Anticodon-binding A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 Gene3D G3DSA:3.40.50.800 329 425 1.2E-20 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 PIRSF PIRSF001549 5 427 2.9E-110 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 Pfam PF13393 Histidyl-tRNA synthetase 12 314 2.5E-42 T 14-10-2018 A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 10 416 3.6E-102 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 SUPERFAMILY SSF55681 10 323 5.18E-65 T 14-10-2018 A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 Gene3D G3DSA:3.30.930.10 5 326 1.2E-88 T 14-10-2018 A4R43_34905 c16503d28d91577b97c9b85bb6d682fa 428 SUPERFAMILY SSF52954 335 427 1.36E-19 T 14-10-2018 A4R43_15685 990594187eb81fe37f5bcb5eb5414105 267 SMART SM00346 19 109 2.9E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_15685 990594187eb81fe37f5bcb5eb5414105 267 SUPERFAMILY SSF55781 87 261 9.81E-42 T 14-10-2018 A4R43_15685 990594187eb81fe37f5bcb5eb5414105 267 Pfam PF01614 Bacterial transcriptional regulator 138 253 3.3E-26 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_15685 990594187eb81fe37f5bcb5eb5414105 267 SUPERFAMILY SSF46785 19 92 1.0E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15685 990594187eb81fe37f5bcb5eb5414105 267 Pfam PF09339 IclR helix-turn-helix domain 21 71 3.5E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_15685 990594187eb81fe37f5bcb5eb5414105 267 Gene3D G3DSA:3.30.450.40 95 264 5.0E-45 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_15685 990594187eb81fe37f5bcb5eb5414105 267 Gene3D G3DSA:1.10.10.10 4 80 7.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22925 c30ca7acf7355e4cf7e3ad748e46043f 537 Pfam PF01039 Carboxyl transferase domain 50 527 2.4E-153 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_22925 c30ca7acf7355e4cf7e3ad748e46043f 537 Gene3D G3DSA:3.90.226.10 275 537 2.8E-104 T 14-10-2018 A4R43_22925 c30ca7acf7355e4cf7e3ad748e46043f 537 SUPERFAMILY SSF52096 278 537 1.54E-87 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_22925 c30ca7acf7355e4cf7e3ad748e46043f 537 Gene3D G3DSA:3.90.226.10 14 273 1.4E-95 T 14-10-2018 A4R43_22925 c30ca7acf7355e4cf7e3ad748e46043f 537 SUPERFAMILY SSF52096 28 272 5.12E-71 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 Gene3D G3DSA:2.70.98.10 27 295 1.3E-91 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 SMART SM01065 710 800 1.2E-29 T 14-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 SUPERFAMILY SSF74650 24 293 1.57E-77 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 SUPERFAMILY SSF48208 306 704 2.04E-77 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 Pfam PF09137 Glucodextranase, domain N 31 290 2.8E-90 T 14-10-2018 IPR015220 Glucodextranase, N-terminal KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 Gene3D G3DSA:1.50.10.10 298 705 1.1E-176 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 TIGRFAM TIGR01535 glucan_glucosid: glucan 1,4-alpha-glucosidase 57 704 1.0E-239 T 14-10-2018 IPR006425 Glucoamylase, bacterial KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 SUPERFAMILY SSF49452 711 803 3.19E-29 T 14-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 Pfam PF00686 Starch binding domain 711 792 1.2E-27 T 14-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 Gene3D G3DSA:2.60.40.10 706 804 4.9E-32 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 Pfam PF00723 Glycosyl hydrolases family 15 391 640 1.7E-29 T 14-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 A4R43_40445 5a836ddccc126c2b752bf01ab93bd630 804 ProSitePatterns PS00820 Glucoamylase active site region signature. 447 457 - T 14-10-2018 IPR000165 Glucoamylase GO:0004339|GO:0005976 KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 SUPERFAMILY SSF53901 8 358 8.65E-68 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 SUPERFAMILY SSF47336 709 810 1.09E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Gene3D G3DSA:1.10.1200.10 695 782 1.5E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Gene3D G3DSA:3.30.70.3290 650 687 6.6E-8 T 14-10-2018 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 SMART SM00823 Phosphopantetheine attachment site 709 778 5.1E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Gene3D G3DSA:3.40.366.10 510 521 3.3E-11 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Gene3D G3DSA:3.30.559.30 976 1227 1.5E-130 T 14-10-2018 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Gene3D G3DSA:3.30.559.10 799 1165 1.5E-130 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 369 479 1.2E-13 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Gene3D G3DSA:3.40.47.10 1 419 6.5E-129 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Pfam PF00668 Condensation domain 796 1230 1.3E-82 T 14-10-2018 IPR001242 Condensation domain A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Gene3D G3DSA:3.40.366.10 609 649 6.6E-8 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 SMART SM00825 Beta-ketoacyl synthase 12 419 1.2E-113 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 SUPERFAMILY SSF52777 800 972 1.0E-47 T 14-10-2018 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 247 5.6E-51 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Pfam PF00550 Phosphopantetheine attachment site 712 774 8.0E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 366 1.9E-29 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 SUPERFAMILY SSF52777 979 1226 4.0E-51 T 14-10-2018 A4R43_12565 495a6e2da81af475874e3b27a6e90167 1238 Gene3D G3DSA:3.30.70.3290 434 509 3.3E-11 T 14-10-2018 A4R43_07955 30b27b491f826d66a986d54be5728589 320 SUPERFAMILY SSF51735 103 260 3.73E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07955 30b27b491f826d66a986d54be5728589 320 SMART SM00829 10 318 8.4E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_07955 30b27b491f826d66a986d54be5728589 320 SUPERFAMILY SSF50129 1 134 5.19E-24 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_07955 30b27b491f826d66a986d54be5728589 320 Pfam PF00107 Zinc-binding dehydrogenase 144 210 2.4E-9 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_07955 30b27b491f826d66a986d54be5728589 320 Gene3D G3DSA:3.90.180.10 1 320 5.2E-50 T 14-10-2018 A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 SUPERFAMILY SSF46785 9 69 2.66E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 Gene3D G3DSA:1.10.10.10 2 60 3.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 Pfam PF13404 AsnC-type helix-turn-helix domain 9 50 1.0E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 Pfam PF01037 Lrp/AsnC ligand binding domain 91 140 2.7E-10 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 SMART SM00344 9 115 2.2E-34 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 Gene3D G3DSA:3.30.70.920 61 147 9.8E-17 T 14-10-2018 A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 SUPERFAMILY SSF54909 70 144 5.23E-13 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 4.0E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 4.0E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_31335 caeda92c3f9e0f0f6e91c417ee070196 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 4.0E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_39520 fdbf45069dd35ce205f15bb39f196e18 410 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 36 366 3.8E-73 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 A4R43_39520 fdbf45069dd35ce205f15bb39f196e18 410 SUPERFAMILY SSF102114 24 408 3.79E-103 T 14-10-2018 A4R43_39520 fdbf45069dd35ce205f15bb39f196e18 410 Pfam PF04055 Radical SAM superfamily 38 213 7.7E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_39520 fdbf45069dd35ce205f15bb39f196e18 410 Gene3D G3DSA:3.80.30.20 17 333 5.2E-89 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4R43_39520 fdbf45069dd35ce205f15bb39f196e18 410 SMART SM00729 33 258 7.3E-53 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_15335 131de5ca706eb904c2e2801a7cca4a2f 141 Pfam PF12680 SnoaL-like domain 11 111 3.7E-8 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_15335 131de5ca706eb904c2e2801a7cca4a2f 141 SUPERFAMILY SSF54427 3 118 9.86E-25 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_15335 131de5ca706eb904c2e2801a7cca4a2f 141 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 3 118 1.5E-18 T 14-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 A4R43_15335 131de5ca706eb904c2e2801a7cca4a2f 141 Gene3D G3DSA:3.10.450.50 2 135 2.5E-26 T 14-10-2018 A4R43_32265 dee12afdbacd29f60697074f58344837 837 Pfam PF00698 Acyl transferase domain 511 758 3.4E-49 T 14-10-2018 IPR014043 Acyl transferase A4R43_32265 dee12afdbacd29f60697074f58344837 837 SMART SM00826 3 132 4.5E-5 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_32265 dee12afdbacd29f60697074f58344837 837 Gene3D G3DSA:3.40.47.10 181 388 5.3E-41 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_32265 dee12afdbacd29f60697074f58344837 837 SUPERFAMILY SSF53901 194 378 1.89E-32 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_32265 dee12afdbacd29f60697074f58344837 837 Gene3D G3DSA:3.10.129.110 5 142 1.6E-13 T 14-10-2018 A4R43_32265 dee12afdbacd29f60697074f58344837 837 SMART SM00825 Beta-ketoacyl synthase 196 508 2.3E-15 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_32265 dee12afdbacd29f60697074f58344837 837 SUPERFAMILY SSF52151 498 773 1.05E-44 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_32265 dee12afdbacd29f60697074f58344837 837 Gene3D G3DSA:3.30.70.3290 417 497 8.1E-98 T 14-10-2018 A4R43_32265 dee12afdbacd29f60697074f58344837 837 Gene3D G3DSA:3.30.70.3290 767 807 5.7E-12 T 14-10-2018 A4R43_32265 dee12afdbacd29f60697074f58344837 837 Gene3D G3DSA:3.40.366.10 498 766 8.1E-98 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_32265 dee12afdbacd29f60697074f58344837 837 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 222 355 6.8E-25 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_32265 dee12afdbacd29f60697074f58344837 837 SUPERFAMILY SSF55048 617 680 1.57E-9 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_32265 dee12afdbacd29f60697074f58344837 837 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 512 795 3.7E-52 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_05275 1d474402e8fa7e136ff66ddf8dd0e954 319 Gene3D G3DSA:1.10.10.10 2 68 2.5E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05275 1d474402e8fa7e136ff66ddf8dd0e954 319 Pfam PF08279 HTH domain 10 65 6.5E-14 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_05275 1d474402e8fa7e136ff66ddf8dd0e954 319 SUPERFAMILY SSF46785 7 66 1.22E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05275 1d474402e8fa7e136ff66ddf8dd0e954 319 PIRSF PIRSF016838 68 319 3.3E-21 T 14-10-2018 IPR028349 Protein PafC A4R43_05275 1d474402e8fa7e136ff66ddf8dd0e954 319 PIRSF PIRSF016838 3 61 0.013 T 14-10-2018 IPR028349 Protein PafC A4R43_05275 1d474402e8fa7e136ff66ddf8dd0e954 319 Pfam PF13280 WYL domain 145 314 5.6E-32 T 14-10-2018 IPR026881 WYL domain A4R43_09580 8e91cd21a0f129bbf4de3b6983b1a0a9 180 Pfam PF11706 CGNR zinc finger 133 175 3.4E-15 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_09580 8e91cd21a0f129bbf4de3b6983b1a0a9 180 Gene3D G3DSA:1.10.3300.10 8 177 2.2E-20 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_09580 8e91cd21a0f129bbf4de3b6983b1a0a9 180 Pfam PF07336 Putative stress-induced transcription regulator 8 128 5.4E-18 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator A4R43_09580 8e91cd21a0f129bbf4de3b6983b1a0a9 180 SUPERFAMILY SSF160904 3 174 2.62E-37 T 14-10-2018 A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 Gene3D G3DSA:3.40.50.2300 167 294 3.3E-56 T 14-10-2018 A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 SMART SM00354 3 73 1.1E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 SUPERFAMILY SSF53822 78 321 5.26E-51 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 Gene3D G3DSA:3.40.50.2300 57 309 3.3E-56 T 14-10-2018 A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 14-10-2018 A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 SUPERFAMILY SSF47413 2 60 9.38E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 Gene3D G3DSA:1.10.260.40 1 56 8.4E-21 T 14-10-2018 A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 Pfam PF13377 Periplasmic binding protein-like domain 176 333 2.0E-33 T 14-10-2018 A4R43_06500 ad0c6bdae8f2da9de1fd4cf5cc1bb068 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 5.5E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 Gene3D G3DSA:3.30.465.10 70 192 4.0E-41 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 Pfam PF01565 FAD binding domain 15 150 5.0E-25 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 4 432 7.9E-122 T 14-10-2018 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 15 48 - T 14-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 Gene3D G3DSA:3.30.70.2520 302 394 1.1E-23 T 14-10-2018 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 PIRSF PIRSF000136 1 434 1.8E-116 T 14-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 Gene3D G3DSA:1.10.45.10 395 432 1.7E-12 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 Gene3D G3DSA:3.30.43.10 1 66 7.8E-20 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 Pfam PF04030 D-arabinono-1,4-lactone oxidase 174 430 9.6E-74 T 14-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 A4R43_28955 33cdb47c309ace39ca81d8fe3e498dfe 435 SUPERFAMILY SSF56176 2 180 8.88E-46 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 68 82 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 Gene3D G3DSA:3.10.310.10 3 134 1.9E-89 T 14-10-2018 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 Pfam PF01678 Diaminopimelate epimerase 144 256 1.3E-20 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 Pfam PF01678 Diaminopimelate epimerase 3 127 9.5E-37 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 Gene3D G3DSA:3.10.310.10 135 260 1.9E-89 T 14-10-2018 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 264 30.331 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 262 4.6E-70 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 SUPERFAMILY SSF54506 133 262 1.45E-32 T 14-10-2018 A4R43_16845 83e3abb0e45e6fc912785f963b8aeb81 271 SUPERFAMILY SSF54506 1 128 1.41E-35 T 14-10-2018 A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.3E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 3.3E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.3E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 SMART SM00344 5 111 1.3E-31 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 Gene3D G3DSA:3.30.70.920 57 140 1.3E-18 T 14-10-2018 A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 Gene3D G3DSA:1.10.10.10 1 56 9.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 SUPERFAMILY SSF46785 5 65 4.43E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 SUPERFAMILY SSF54909 66 138 1.34E-13 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 Pfam PF01037 Lrp/AsnC ligand binding domain 81 137 7.9E-12 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_08770 d75fa6b772b908032bfbf728d1ba9a8a 154 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 1.9E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_23510 291d54bfff46d4a392ca2c7cfd359ec5 356 Gene3D G3DSA:3.30.540.10 22 325 3.5E-134 T 14-10-2018 A4R43_23510 291d54bfff46d4a392ca2c7cfd359ec5 356 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 18 329 4.0E-119 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4R43_23510 291d54bfff46d4a392ca2c7cfd359ec5 356 PIRSF PIRSF004532 16 336 2.8E-150 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4R43_23510 291d54bfff46d4a392ca2c7cfd359ec5 356 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 18 325 4.1E-145 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4R43_23510 291d54bfff46d4a392ca2c7cfd359ec5 356 Gene3D G3DSA:3.40.190.90 138 299 3.5E-134 T 14-10-2018 A4R43_23510 291d54bfff46d4a392ca2c7cfd359ec5 356 SUPERFAMILY SSF56655 16 328 1.1E-114 T 14-10-2018 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 Gene3D G3DSA:3.40.50.720 101 282 2.8E-121 T 14-10-2018 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 SUPERFAMILY SSF143548 325 453 1.44E-31 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 SUPERFAMILY SSF52283 6 137 1.32E-37 T 14-10-2018 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 Gene3D G3DSA:3.30.70.260 458 531 9.2E-21 T 14-10-2018 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 284 5.5E-63 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 316 1.2E-33 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 Gene3D G3DSA:3.40.50.720 10 308 2.8E-121 T 14-10-2018 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 Pfam PF01842 ACT domain 460 516 5.8E-11 T 14-10-2018 IPR002912 ACT domain A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 SUPERFAMILY SSF55021 456 529 1.12E-13 T 14-10-2018 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 SUPERFAMILY SSF51735 103 284 1.27E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 9 530 9.5E-185 T 14-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 Gene3D G3DSA:3.30.1330.90 319 457 7.1E-41 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A4R43_19960 99ae2735663757b010e2d9d1c7abfb0c 532 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4R43_14350 66a8d3cd3aa322c9a3a456b98982d0a5 355 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 1.3E-17 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4R43_14350 66a8d3cd3aa322c9a3a456b98982d0a5 355 SUPERFAMILY SSF46589 31 115 3.98E-15 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A4R43_14350 66a8d3cd3aa322c9a3a456b98982d0a5 355 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 351 44.489 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 A4R43_14350 66a8d3cd3aa322c9a3a456b98982d0a5 355 SUPERFAMILY SSF55681 109 348 2.19E-77 T 14-10-2018 A4R43_14350 66a8d3cd3aa322c9a3a456b98982d0a5 355 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 60 347 4.4E-89 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4R43_14350 66a8d3cd3aa322c9a3a456b98982d0a5 355 Gene3D G3DSA:3.30.930.10 25 353 7.2E-107 T 14-10-2018 A4R43_14350 66a8d3cd3aa322c9a3a456b98982d0a5 355 Pfam PF01409 tRNA synthetases class II core domain (F) 109 348 6.6E-100 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 1.1E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 1.1E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 1.1E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 SUPERFAMILY SSF52172 3 133 4.27E-30 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 SMART SM00448 3 117 4.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 Gene3D G3DSA:3.40.50.12740 3 206 3.3E-64 T 14-10-2018 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 Pfam PF00072 Response regulator receiver domain 5 115 9.8E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 200 5.0E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 SUPERFAMILY SSF46894 135 206 2.18E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_07660 a406c0f0a98e6c8dc852a75d3f2f5128 215 SMART SM00421 143 200 8.3E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05925 8fc6d11410bf0ce2a88bf76be1e7648d 314 Gene3D G3DSA:1.20.1050.10 154 314 6.3E-71 T 14-10-2018 A4R43_05925 8fc6d11410bf0ce2a88bf76be1e7648d 314 PIRSF PIRSF015753 1 299 2.7E-106 T 14-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 A4R43_05925 8fc6d11410bf0ce2a88bf76be1e7648d 314 SUPERFAMILY SSF52833 14 117 1.34E-6 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_05925 8fc6d11410bf0ce2a88bf76be1e7648d 314 Pfam PF13409 Glutathione S-transferase, N-terminal domain 38 128 4.2E-11 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A4R43_05925 8fc6d11410bf0ce2a88bf76be1e7648d 314 SUPERFAMILY SSF47616 155 309 2.65E-32 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily A4R43_05925 8fc6d11410bf0ce2a88bf76be1e7648d 314 Gene3D G3DSA:3.40.30.130 1 153 1.1E-55 T 14-10-2018 A4R43_05925 8fc6d11410bf0ce2a88bf76be1e7648d 314 Pfam PF13410 Glutathione S-transferase, C-terminal domain 178 249 2.1E-12 T 14-10-2018 A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 SUPERFAMILY SSF52540 11 246 2.16E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 SUPERFAMILY SSF50331 239 361 3.64E-22 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 SMART SM00382 31 214 1.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 Gene3D G3DSA:3.40.50.300 6 224 4.6E-61 T 14-10-2018 A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 Pfam PF00005 ABC transporter 23 164 2.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 Pfam PF08402 TOBE domain 281 353 4.4E-6 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 Gene3D G3DSA:2.40.50.140 288 344 5.6E-30 T 14-10-2018 A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_06445 ed81a5ebc498fcfb36ea2178695568c7 363 Gene3D G3DSA:2.40.50.940 225 354 5.6E-30 T 14-10-2018 A4R43_41685 4acd556ded84af9fefa0f46f24326fb5 346 Gene3D G3DSA:3.40.50.1100 154 303 1.6E-46 T 14-10-2018 A4R43_41685 4acd556ded84af9fefa0f46f24326fb5 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 41 281 7.2E-31 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_41685 4acd556ded84af9fefa0f46f24326fb5 346 SUPERFAMILY SSF53686 40 307 2.33E-46 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_41685 4acd556ded84af9fefa0f46f24326fb5 346 Gene3D G3DSA:3.40.50.1100 40 153 1.6E-46 T 14-10-2018 A4R43_00185 b4d3cfb8f8cfceed2187f50fe8aca5bf 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 283 5.9E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_00185 b4d3cfb8f8cfceed2187f50fe8aca5bf 290 SUPERFAMILY SSF161098 21 290 1.12E-70 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_00185 b4d3cfb8f8cfceed2187f50fe8aca5bf 290 Gene3D G3DSA:1.10.3720.10 20 277 4.2E-61 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_39945 1ea1bc482a0ba6c764785641bca0db04 312 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 68 291 1.6E-59 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_39945 1ea1bc482a0ba6c764785641bca0db04 312 Gene3D G3DSA:3.90.850.10 1 299 1.0E-81 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_39945 1ea1bc482a0ba6c764785641bca0db04 312 SUPERFAMILY SSF56529 65 291 6.8E-65 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 193 4.7E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 142 161 4.7E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 333 349 4.7E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 Pfam PF00082 Subtilase family 144 372 2.0E-38 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 Gene3D G3DSA:3.40.50.200 112 393 1.1E-91 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 SUPERFAMILY SSF49785 406 509 2.98E-15 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 Gene3D G3DSA:2.60.120.260 397 506 5.1E-8 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 SUPERFAMILY SSF52743 114 371 4.06E-76 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 Pfam PF05922 Peptidase inhibitor I9 66 105 1.2E-7 T 14-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 334 344 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 184 194 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 SUPERFAMILY SSF54897 48 110 4.14E-13 T 14-10-2018 A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 Pfam PF01483 Proprotein convertase P-domain 433 509 1.4E-13 T 14-10-2018 IPR002884 P domain GO:0004252|GO:0006508 A4R43_38330 146ab149362e5cfdae61a31616a80ad5 510 Gene3D G3DSA:3.30.70.80 40 111 1.1E-19 T 14-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A4R43_04135 992d632c184a7b10edc272df3a473fdc 605 SUPERFAMILY SSF49265 415 498 2.2E-15 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_04135 992d632c184a7b10edc272df3a473fdc 605 Gene3D G3DSA:2.60.40.10 414 512 9.6E-15 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_04135 992d632c184a7b10edc272df3a473fdc 605 Pfam PF00041 Fibronectin type III domain 421 498 2.1E-9 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_04135 992d632c184a7b10edc272df3a473fdc 605 SMART SM00060 419 497 1.0E-8 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_04135 992d632c184a7b10edc272df3a473fdc 605 SUPERFAMILY SSF63829 150 353 2.58E-5 T 14-10-2018 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 SMART SM00421 904 961 1.4E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 Gene3D G3DSA:1.10.10.10 886 961 4.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 SUPERFAMILY SSF52540 16 252 5.1E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 ProSitePatterns PS00622 LuxR-type HTH domain signature. 921 948 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 Pfam PF00196 Bacterial regulatory proteins, luxR family 906 957 9.3E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 SUPERFAMILY SSF46894 898 959 4.76E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 Gene3D G3DSA:1.25.40.10 593 885 1.7E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 Gene3D G3DSA:3.40.50.300 4 190 2.7E-8 T 14-10-2018 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 Pfam PF13191 AAA ATPase domain 17 178 7.2E-22 T 14-10-2018 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 907 921 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 937 949 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27980 37c81f5140994e2e7d378fd3b4361f98 967 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 921 937 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16475 94574a2878ada128ddb0d792d66e1dc0 576 Pfam PF13515 Fusaric acid resistance protein-like 326 434 2.8E-6 T 14-10-2018 A4R43_03040 62142f7e9fd4e9a19170b063b70eb06b 328 Pfam PF03741 Integral membrane protein TerC family 79 285 5.0E-48 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A4R43_03040 62142f7e9fd4e9a19170b063b70eb06b 328 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 14 321 6.8E-106 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 SUPERFAMILY SSF81665 204 710 6.02E-11 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 207 736 9.7E-109 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 SUPERFAMILY SSF55008 11 78 3.4E-17 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 203 737 1.0E-153 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 SUPERFAMILY SSF56784 436 734 1.0E-54 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 SUPERFAMILY SSF81653 244 338 1.57E-24 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 212 716 1.0E-85 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 Pfam PF00122 E1-E2 ATPase 241 416 6.9E-53 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 45 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 Pfam PF00702 haloacid dehalogenase-like hydrolase 434 648 3.7E-49 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 Gene3D G3DSA:2.70.150.20 227 342 1.1E-34 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 438 452 3.6E-24 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 581 591 3.6E-24 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 288 302 3.6E-24 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 653 3.6E-24 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 657 669 3.6E-24 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 Gene3D G3DSA:3.30.70.100 9 80 1.9E-18 T 14-10-2018 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 665 690 9.1E-8 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 606 622 9.1E-8 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 634 650 9.1E-8 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 157 736 1.3E-176 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 Gene3D G3DSA:3.40.1110.10 449 566 5.3E-85 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 Pfam PF00403 Heavy-metal-associated domain 15 72 4.9E-13 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 Gene3D G3DSA:3.40.50.1000 419 686 5.3E-85 T 14-10-2018 IPR023214 HAD superfamily A4R43_21920 3206b7d2e31fdbc7cbd9482059b5b244 748 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 440 446 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4R43_27880 48d073191d612bc28be67a8156f9d14b 137 Gene3D G3DSA:3.30.565.10 6 133 1.7E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_10215 6dd7d0f12d9d93f51ea82381cb395ec2 216 Gene3D G3DSA:3.40.50.2300 1 118 2.7E-27 T 14-10-2018 A4R43_10215 6dd7d0f12d9d93f51ea82381cb395ec2 216 SUPERFAMILY SSF52172 2 176 7.47E-32 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_10215 6dd7d0f12d9d93f51ea82381cb395ec2 216 Pfam PF00072 Response regulator receiver domain 3 109 7.5E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_10215 6dd7d0f12d9d93f51ea82381cb395ec2 216 SMART SM00448 1 109 3.5E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_10215 6dd7d0f12d9d93f51ea82381cb395ec2 216 SMART SM00862 144 214 4.4E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_10215 6dd7d0f12d9d93f51ea82381cb395ec2 216 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 214 2.1E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_10215 6dd7d0f12d9d93f51ea82381cb395ec2 216 Gene3D G3DSA:1.10.10.10 122 216 1.2E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08630 0044ba59f831afcd8309a2987926f12e 181 SUPERFAMILY SSF143990 13 180 7.59E-50 T 14-10-2018 IPR037238 YbiA-like superfamily A4R43_08630 0044ba59f831afcd8309a2987926f12e 181 Pfam PF08719 Domain of unknown function (DUF1768) 21 179 6.5E-52 T 14-10-2018 IPR012816 NADAR A4R43_08630 0044ba59f831afcd8309a2987926f12e 181 Gene3D G3DSA:1.10.357.40 27 181 1.6E-41 T 14-10-2018 IPR037238 YbiA-like superfamily A4R43_08630 0044ba59f831afcd8309a2987926f12e 181 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 21 178 5.6E-48 T 14-10-2018 IPR012816 NADAR A4R43_13605 0ac77e9f80aeea34783186584de594c2 581 Pfam PF04183 IucA / IucC family 125 368 3.7E-71 T 14-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 A4R43_13605 0ac77e9f80aeea34783186584de594c2 581 Pfam PF06276 Ferric iron reductase FhuF-like transporter 392 547 5.5E-27 T 14-10-2018 IPR022770 Ferric iron reductase FhuF domain A4R43_13605 0ac77e9f80aeea34783186584de594c2 581 Gene3D G3DSA:1.10.510.40 359 561 8.5E-49 T 14-10-2018 A4R43_13605 0ac77e9f80aeea34783186584de594c2 581 Gene3D G3DSA:1.10.274.90 1 110 4.5E-19 T 14-10-2018 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 SUPERFAMILY SSF46894 143 206 6.8E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 SUPERFAMILY SSF52172 1 127 1.42E-31 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_15380 47d256850204dffb814164cd6e873bf2 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 SMART SM00421 148 205 1.4E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 1.2E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 Gene3D G3DSA:3.40.50.12740 2 209 2.5E-61 T 14-10-2018 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 Pfam PF00072 Response regulator receiver domain 4 111 2.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15380 47d256850204dffb814164cd6e873bf2 210 SMART SM00448 2 111 5.0E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_37010 0a58509be4405eed9b98b586f30f3b45 199 Gene3D G3DSA:1.10.3130.10 1 74 5.2E-7 T 14-10-2018 A4R43_37010 0a58509be4405eed9b98b586f30f3b45 199 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 142 170 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A4R43_37010 0a58509be4405eed9b98b586f30f3b45 199 PIRSF PIRSF000441 7 197 2.4E-55 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 A4R43_37010 0a58509be4405eed9b98b586f30f3b45 199 SUPERFAMILY SSF51161 19 176 1.57E-37 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_37010 0a58509be4405eed9b98b586f30f3b45 199 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 166 3.5E-7 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_37010 0a58509be4405eed9b98b586f30f3b45 199 Gene3D G3DSA:2.160.10.10 77 194 1.5E-29 T 14-10-2018 A4R43_28595 f8d5a00fc98dde15f57961d672e0ede1 170 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 7 158 1.3E-50 T 14-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4R43_28595 f8d5a00fc98dde15f57961d672e0ede1 170 SUPERFAMILY SSF88946 2 90 1.88E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_28595 f8d5a00fc98dde15f57961d672e0ede1 170 SUPERFAMILY SSF88659 98 157 5.79E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_28595 f8d5a00fc98dde15f57961d672e0ede1 170 Gene3D G3DSA:1.10.10.10 79 159 4.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28595 f8d5a00fc98dde15f57961d672e0ede1 170 Pfam PF04542 Sigma-70 region 2 11 79 9.2E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_28595 f8d5a00fc98dde15f57961d672e0ede1 170 Pfam PF08281 Sigma-70, region 4 102 153 4.5E-19 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_28595 f8d5a00fc98dde15f57961d672e0ede1 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 157 1.1E-25 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_28595 f8d5a00fc98dde15f57961d672e0ede1 170 Gene3D G3DSA:1.10.1740.10 4 78 7.4E-9 T 14-10-2018 A4R43_05660 d6085d76241698808cd75fd29f8f7691 457 Gene3D G3DSA:1.20.1250.20 17 453 1.0E-68 T 14-10-2018 A4R43_05660 d6085d76241698808cd75fd29f8f7691 457 SUPERFAMILY SSF103473 12 446 7.85E-59 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_05660 d6085d76241698808cd75fd29f8f7691 457 Pfam PF00083 Sugar (and other) transporter 23 445 2.3E-36 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_05660 d6085d76241698808cd75fd29f8f7691 457 ProSitePatterns PS00216 Sugar transport proteins signature 1. 313 329 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_39825 e6eafd0d8104cf80048c150426d2725f 311 SUPERFAMILY SSF53850 8 288 1.51E-50 T 14-10-2018 A4R43_39825 e6eafd0d8104cf80048c150426d2725f 311 Gene3D G3DSA:3.40.190.10 66 286 6.4E-58 T 14-10-2018 A4R43_39825 e6eafd0d8104cf80048c150426d2725f 311 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 74 287 1.9E-43 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_39825 e6eafd0d8104cf80048c150426d2725f 311 Gene3D G3DSA:3.40.190.10 162 252 6.4E-58 T 14-10-2018 A4R43_39825 e6eafd0d8104cf80048c150426d2725f 311 SMART SM00062 72 294 8.2E-51 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 10 471 7.9E-241 T 14-10-2018 IPR014065 tRNA adenylyltransferase A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 TIGRFAM TIGR00277 HDIG: HDIG domain 258 343 1.9E-19 T 14-10-2018 IPR006675 HDIG domain A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 Pfam PF01743 Poly A polymerase head domain 35 158 7.5E-31 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 SUPERFAMILY SSF81891 158 471 1.03E-64 T 14-10-2018 A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 Gene3D G3DSA:3.30.460.10 18 157 6.3E-36 T 14-10-2018 A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 SUPERFAMILY SSF81301 17 152 1.09E-34 T 14-10-2018 A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 SMART SM00471 257 428 8.2E-8 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 186 245 5.7E-18 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 Gene3D G3DSA:1.10.3090.10 158 461 6.1E-47 T 14-10-2018 A4R43_30540 eef893c0d19d69b785bed94e4882df17 487 Pfam PF01966 HD domain 261 413 2.0E-15 T 14-10-2018 IPR006674 HD domain A4R43_27660 8e3d299192cf7f6695cdc03a9efa938c 317 Gene3D G3DSA:1.10.3660.10 167 272 1.6E-85 T 14-10-2018 A4R43_27660 8e3d299192cf7f6695cdc03a9efa938c 317 Gene3D G3DSA:3.40.50.720 1 166 1.6E-85 T 14-10-2018 A4R43_27660 8e3d299192cf7f6695cdc03a9efa938c 317 SUPERFAMILY SSF51735 1 162 6.35E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_27660 8e3d299192cf7f6695cdc03a9efa938c 317 Pfam PF02153 Prephenate dehydrogenase 18 241 4.6E-46 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A4R43_27660 8e3d299192cf7f6695cdc03a9efa938c 317 SUPERFAMILY SSF48179 167 252 6.12E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 Gene3D G3DSA:1.20.1640.10 143 354 3.2E-6 T 14-10-2018 A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 Pfam PF02355 Protein export membrane protein 141 329 9.0E-56 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 29 331 23.234 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 SUPERFAMILY SSF82866 123 329 9.81E-31 T 14-10-2018 A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 Pfam PF07549 SecD/SecF GG Motif 52 74 3.9E-9 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 PRINTS PR01755 Bacterial translocase SecF protein signature 228 246 1.9E-22 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 PRINTS PR01755 Bacterial translocase SecF protein signature 263 278 1.9E-22 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 PRINTS PR01755 Bacterial translocase SecF protein signature 56 71 1.9E-22 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 PRINTS PR01755 Bacterial translocase SecF protein signature 180 194 1.9E-22 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 143 317 6.5E-48 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4R43_04345 27e857377d4d29fca4a03bbb65eb76d4 413 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 57 320 2.2E-68 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4R43_11585 00b9aa30ab84eeda68f224cadb632c2d 357 PRINTS PR00625 DnaJ domain signature 7 25 4.5E-10 T 14-10-2018 IPR001623 DnaJ domain A4R43_11585 00b9aa30ab84eeda68f224cadb632c2d 357 PRINTS PR00625 DnaJ domain signature 38 58 4.5E-10 T 14-10-2018 IPR001623 DnaJ domain A4R43_11585 00b9aa30ab84eeda68f224cadb632c2d 357 Pfam PF08378 Nuclease-related domain 201 271 1.1E-4 T 14-10-2018 IPR011528 Nuclease-related domain, NERD A4R43_11585 00b9aa30ab84eeda68f224cadb632c2d 357 SMART SM00271 4 58 7.6E-19 T 14-10-2018 IPR001623 DnaJ domain A4R43_11585 00b9aa30ab84eeda68f224cadb632c2d 357 ProSitePatterns PS00636 Nt-dnaJ domain signature. 43 62 - T 14-10-2018 IPR018253 DnaJ domain, conserved site A4R43_11585 00b9aa30ab84eeda68f224cadb632c2d 357 Gene3D G3DSA:1.10.287.110 2 91 5.2E-22 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_11585 00b9aa30ab84eeda68f224cadb632c2d 357 Pfam PF00226 DnaJ domain 5 63 6.9E-19 T 14-10-2018 IPR001623 DnaJ domain A4R43_11585 00b9aa30ab84eeda68f224cadb632c2d 357 SUPERFAMILY SSF46565 4 68 3.4E-23 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_07510 882ff7fd358004511d192dabf2775ef0 487 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 319 457 7.4E-30 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A4R43_07510 882ff7fd358004511d192dabf2775ef0 487 Pfam PF00535 Glycosyl transferase family 2 7 115 2.3E-12 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_07510 882ff7fd358004511d192dabf2775ef0 487 Gene3D G3DSA:3.90.550.10 3 196 2.9E-27 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_07510 882ff7fd358004511d192dabf2775ef0 487 SUPERFAMILY SSF53448 6 205 6.75E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_07510 882ff7fd358004511d192dabf2775ef0 487 Pfam PF13242 HAD-hyrolase-like 410 481 1.3E-16 T 14-10-2018 A4R43_07510 882ff7fd358004511d192dabf2775ef0 487 Gene3D G3DSA:3.40.50.1000 306 486 2.4E-47 T 14-10-2018 IPR023214 HAD superfamily A4R43_07510 882ff7fd358004511d192dabf2775ef0 487 SUPERFAMILY SSF56784 314 485 3.98E-43 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_07510 882ff7fd358004511d192dabf2775ef0 487 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 319 456 4.9E-32 T 14-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 A4R43_30650 d97785c494779e454199b1afef4e3200 547 Gene3D G3DSA:3.50.30.10 10 226 5.5E-56 T 14-10-2018 A4R43_30650 d97785c494779e454199b1afef4e3200 547 Gene3D G3DSA:3.20.20.60 242 546 3.0E-96 T 14-10-2018 A4R43_30650 d97785c494779e454199b1afef4e3200 547 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 517 1.3E-79 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A4R43_30650 d97785c494779e454199b1afef4e3200 547 Pfam PF00391 PEP-utilising enzyme, mobile domain 155 223 6.7E-22 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4R43_30650 d97785c494779e454199b1afef4e3200 547 Gene3D G3DSA:1.10.274.10 27 146 5.5E-56 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 A4R43_30650 d97785c494779e454199b1afef4e3200 547 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A4R43_30650 d97785c494779e454199b1afef4e3200 547 PIRSF PIRSF000732 3 546 8.0E-150 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A4R43_30650 d97785c494779e454199b1afef4e3200 547 SUPERFAMILY SSF51621 248 527 3.4E-85 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_30650 d97785c494779e454199b1afef4e3200 547 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 425 440 1.4E-18 T 14-10-2018 A4R43_30650 d97785c494779e454199b1afef4e3200 547 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 442 457 1.4E-18 T 14-10-2018 A4R43_30650 d97785c494779e454199b1afef4e3200 547 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 478 490 1.4E-18 T 14-10-2018 A4R43_30650 d97785c494779e454199b1afef4e3200 547 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 281 300 1.4E-18 T 14-10-2018 A4R43_30650 d97785c494779e454199b1afef4e3200 547 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 425 443 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A4R43_30650 d97785c494779e454199b1afef4e3200 547 SUPERFAMILY SSF47831 33 143 3.14E-21 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 A4R43_30650 d97785c494779e454199b1afef4e3200 547 SUPERFAMILY SSF52009 125 228 2.62E-27 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A4R43_30650 d97785c494779e454199b1afef4e3200 547 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 57 534 4.6E-111 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A4R43_30650 d97785c494779e454199b1afef4e3200 547 Pfam PF05524 PEP-utilising enzyme, N-terminal 10 126 1.6E-23 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A4R43_26180 8758515d91e53b0d9265eb25fcf99159 362 SUPERFAMILY SSF51905 5 356 4.14E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_26180 8758515d91e53b0d9265eb25fcf99159 362 Gene3D G3DSA:3.50.50.60 7 336 1.1E-76 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_26180 8758515d91e53b0d9265eb25fcf99159 362 Pfam PF01266 FAD dependent oxidoreductase 7 335 1.1E-56 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_26180 8758515d91e53b0d9265eb25fcf99159 362 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 341 4.4E-94 T 14-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 A4R43_26180 8758515d91e53b0d9265eb25fcf99159 362 Gene3D G3DSA:3.30.9.10 87 300 1.1E-76 T 14-10-2018 A4R43_26180 8758515d91e53b0d9265eb25fcf99159 362 SUPERFAMILY SSF54373 207 299 1.7E-16 T 14-10-2018 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 Pfam PF00072 Response regulator receiver domain 4 117 7.8E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 Gene3D G3DSA:3.40.50.12740 2 212 3.8E-70 T 14-10-2018 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 205 4.2E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 SUPERFAMILY SSF52172 2 134 2.99E-32 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 SMART SM00421 149 206 2.5E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 SMART SM00448 2 116 8.0E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.2E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.2E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.2E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_11660 86d5d86af482eac60f2e15e2ced3fa16 215 SUPERFAMILY SSF46894 142 211 9.86E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_25625 9bd0f51bc8382e0cbdb9f09a4023ba5d 97 Gene3D G3DSA:2.10.150.10 1 97 2.6E-45 T 14-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25625 9bd0f51bc8382e0cbdb9f09a4023ba5d 97 SUPERFAMILY SSF51278 1 94 3.4E-44 T 14-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25625 9bd0f51bc8382e0cbdb9f09a4023ba5d 97 Pfam PF00699 Urease beta subunit 3 95 3.9E-42 T 14-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25625 9bd0f51bc8382e0cbdb9f09a4023ba5d 97 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 94 7.2E-38 T 14-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_35330 5166b6479f66c034f9bb0360441ff90e 514 Gene3D G3DSA:2.60.120.260 318 511 2.7E-13 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_35330 5166b6479f66c034f9bb0360441ff90e 514 SUPERFAMILY SSF53474 19 314 2.01E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35330 5166b6479f66c034f9bb0360441ff90e 514 Gene3D G3DSA:3.40.50.1820 16 307 3.1E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35330 5166b6479f66c034f9bb0360441ff90e 514 SMART SM00939 299 505 5.8E-8 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_35330 5166b6479f66c034f9bb0360441ff90e 514 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 43 280 1.4E-19 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4R43_35330 5166b6479f66c034f9bb0360441ff90e 514 SUPERFAMILY SSF49785 332 493 5.95E-13 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_35330 5166b6479f66c034f9bb0360441ff90e 514 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 322 494 2.3E-11 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_15535 4fc5377f030e36fd963e0db428006b92 442 Pfam PF00067 Cytochrome P450 299 412 7.7E-21 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15535 4fc5377f030e36fd963e0db428006b92 442 Gene3D G3DSA:1.10.630.10 46 427 4.4E-37 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15535 4fc5377f030e36fd963e0db428006b92 442 SUPERFAMILY SSF48264 54 419 2.88E-36 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_25300 c53264a2ca3bf8e4570395131938cfea 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25300 c53264a2ca3bf8e4570395131938cfea 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25300 c53264a2ca3bf8e4570395131938cfea 185 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 103 172 2.0E-6 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_25300 c53264a2ca3bf8e4570395131938cfea 185 SUPERFAMILY SSF46689 2 77 5.08E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25300 c53264a2ca3bf8e4570395131938cfea 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 4.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25300 c53264a2ca3bf8e4570395131938cfea 185 SUPERFAMILY SSF48498 75 182 6.02E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_25300 c53264a2ca3bf8e4570395131938cfea 185 Gene3D G3DSA:1.10.357.10 1 183 9.2E-40 T 14-10-2018 A4R43_06505 f293655389fd822d0296c596eba8b1df 433 Gene3D G3DSA:3.20.20.80 28 402 2.3E-108 T 14-10-2018 A4R43_06505 f293655389fd822d0296c596eba8b1df 433 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 190 199 - T 14-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 A4R43_06505 f293655389fd822d0296c596eba8b1df 433 SUPERFAMILY SSF51445 31 405 9.43E-79 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_06505 f293655389fd822d0296c596eba8b1df 433 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 42 376 3.1E-58 T 14-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A4R43_34270 7c60134b00eb883df6d0a48974c4debe 159 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 13 146 4.8E-33 T 14-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A4R43_34270 7c60134b00eb883df6d0a48974c4debe 159 Gene3D G3DSA:3.40.630.30 4 150 6.9E-37 T 14-10-2018 A4R43_34270 7c60134b00eb883df6d0a48974c4debe 159 Pfam PF00583 Acetyltransferase (GNAT) family 19 126 1.5E-16 T 14-10-2018 IPR000182 GNAT domain A4R43_34270 7c60134b00eb883df6d0a48974c4debe 159 SUPERFAMILY SSF55729 3 149 4.97E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_27295 743fca18e47ef1d4a8f0db2d4e61d0d4 351 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 116 132 - T 14-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 A4R43_27295 743fca18e47ef1d4a8f0db2d4e61d0d4 351 SUPERFAMILY SSF53474 78 342 5.41E-69 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27295 743fca18e47ef1d4a8f0db2d4e61d0d4 351 Pfam PF07859 alpha/beta hydrolase fold 116 322 1.7E-74 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_27295 743fca18e47ef1d4a8f0db2d4e61d0d4 351 Gene3D G3DSA:3.40.50.1820 39 350 2.7E-90 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_39970 f2040c31fa299dfdaa83dadee3d6d3b6 546 Gene3D G3DSA:1.10.8.60 411 489 1.9E-7 T 14-10-2018 A4R43_39970 f2040c31fa299dfdaa83dadee3d6d3b6 546 SUPERFAMILY SSF52540 66 224 8.99E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39970 f2040c31fa299dfdaa83dadee3d6d3b6 546 SUPERFAMILY SSF52540 243 484 2.88E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39970 f2040c31fa299dfdaa83dadee3d6d3b6 546 Gene3D G3DSA:3.40.50.300 240 410 2.4E-33 T 14-10-2018 A4R43_39970 f2040c31fa299dfdaa83dadee3d6d3b6 546 SMART SM00382 277 412 2.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_39970 f2040c31fa299dfdaa83dadee3d6d3b6 546 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 281 409 1.3E-24 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_41675 a7b90972905f7044bf1dfa96e5902ead 264 Gene3D G3DSA:3.40.50.300 5 254 2.1E-65 T 14-10-2018 A4R43_41675 a7b90972905f7044bf1dfa96e5902ead 264 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_41675 a7b90972905f7044bf1dfa96e5902ead 264 SUPERFAMILY SSF52540 5 228 8.19E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41675 a7b90972905f7044bf1dfa96e5902ead 264 Pfam PF00005 ABC transporter 24 170 4.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_41675 a7b90972905f7044bf1dfa96e5902ead 264 SMART SM00382 30 214 1.0E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_17785 e5b3b997869d6b6e6b2b50b056e7bcb5 367 Pfam PF01063 Amino-transferase class IV 75 322 2.1E-31 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A4R43_17785 e5b3b997869d6b6e6b2b50b056e7bcb5 367 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 365 2.7E-134 T 14-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A4R43_17785 e5b3b997869d6b6e6b2b50b056e7bcb5 367 Gene3D G3DSA:3.30.470.10 30 362 8.4E-139 T 14-10-2018 A4R43_17785 e5b3b997869d6b6e6b2b50b056e7bcb5 367 ProSitePatterns PS00770 Aminotransferases class-IV signature. 239 272 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 A4R43_17785 e5b3b997869d6b6e6b2b50b056e7bcb5 367 PIRSF PIRSF006468 6 367 2.8E-130 T 14-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A4R43_17785 e5b3b997869d6b6e6b2b50b056e7bcb5 367 SUPERFAMILY SSF56752 9 363 2.09E-113 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A4R43_17785 e5b3b997869d6b6e6b2b50b056e7bcb5 367 Gene3D G3DSA:3.20.10.10 177 349 8.4E-139 T 14-10-2018 A4R43_09730 997a1f3eb87d15d7b67cd42943eb209a 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 114 148 2.8E-7 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_09730 997a1f3eb87d15d7b67cd42943eb209a 210 Gene3D G3DSA:2.160.10.10 3 209 9.7E-59 T 14-10-2018 A4R43_09730 997a1f3eb87d15d7b67cd42943eb209a 210 SUPERFAMILY SSF51161 58 205 6.65E-41 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 357 158.095 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 261 334 1.7E-30 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 Gene3D G3DSA:3.40.50.300 28 189 8.7E-35 T 14-10-2018 A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 SUPERFAMILY SSF46785 264 338 6.19E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 261 335 3.0E-30 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 SUPERFAMILY SSF52540 28 259 3.92E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 32 334 8.3E-137 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 SMART SM00382 59 192 4.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 14 243 2.0E-107 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 Gene3D G3DSA:1.10.8.60 190 264 8.6E-30 T 14-10-2018 A4R43_04330 527b2f4f5b9ae17cda6ef385753ad083 357 Gene3D G3DSA:1.10.10.10 265 344 1.8E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 SUPERFAMILY SSF81442 25 535 2.49E-176 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 480 1.4E-148 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 30 532 1.8E-217 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 Gene3D G3DSA:1.20.210.10 16 541 7.1E-207 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_36250 e4f85aa089e4f8ff65ef65f9a2ac5c9e 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 5.4E-99 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15825 3ce5f23ac6c1c574ed222a9e6bada28c 426 Pfam PF01546 Peptidase family M20/M25/M40 72 361 9.6E-20 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_15825 3ce5f23ac6c1c574ed222a9e6bada28c 426 Gene3D G3DSA:3.30.70.360 191 307 7.7E-112 T 14-10-2018 A4R43_15825 3ce5f23ac6c1c574ed222a9e6bada28c 426 PIRSF PIRSF005962 4 415 4.1E-96 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 A4R43_15825 3ce5f23ac6c1c574ed222a9e6bada28c 426 SUPERFAMILY SSF53187 5 414 1.92E-71 T 14-10-2018 A4R43_15825 3ce5f23ac6c1c574ed222a9e6bada28c 426 Gene3D G3DSA:3.40.630.10 18 364 7.7E-112 T 14-10-2018 A4R43_15825 3ce5f23ac6c1c574ed222a9e6bada28c 426 SUPERFAMILY SSF55031 194 297 2.09E-27 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_15825 3ce5f23ac6c1c574ed222a9e6bada28c 426 Pfam PF07687 Peptidase dimerisation domain 197 289 2.9E-7 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_15825 3ce5f23ac6c1c574ed222a9e6bada28c 426 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 367 4.5E-82 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 PRINTS PR00412 Epoxide hydrolase signature 247 269 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 PRINTS PR00412 Epoxide hydrolase signature 214 230 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 PRINTS PR00412 Epoxide hydrolase signature 30 48 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.6E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 SUPERFAMILY SSF53474 6 269 6.06E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_32745 807f852f84911fa40cb97aa90454123b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 3.9E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 3.9E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 3.9E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 Pfam PF12697 Alpha/beta hydrolase family 26 264 3.5E-21 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_32745 807f852f84911fa40cb97aa90454123b 276 Gene3D G3DSA:3.40.50.1820 2 273 6.9E-67 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14525 d189d25ebf18e3177c08252de01bbef1 213 Pfam PF01872 RibD C-terminal domain 15 195 7.6E-25 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_14525 d189d25ebf18e3177c08252de01bbef1 213 SUPERFAMILY SSF53597 15 200 1.7E-26 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_14525 d189d25ebf18e3177c08252de01bbef1 213 Gene3D G3DSA:3.40.430.10 10 209 2.0E-42 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_34885 4f94267554a17234b3d2a1c92a08838e 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.6E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34885 4f94267554a17234b3d2a1c92a08838e 206 Gene3D G3DSA:1.10.357.10 1 196 7.7E-41 T 14-10-2018 A4R43_34885 4f94267554a17234b3d2a1c92a08838e 206 SUPERFAMILY SSF48498 84 192 7.42E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_34885 4f94267554a17234b3d2a1c92a08838e 206 Pfam PF13305 WHG domain 88 173 2.5E-12 T 14-10-2018 IPR025996 WHG domain A4R43_34885 4f94267554a17234b3d2a1c92a08838e 206 SUPERFAMILY SSF46689 4 76 3.18E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35640 ab6eeedd2654497124a675251c56e3fd 301 SUPERFAMILY SSF53850 101 301 2.17E-44 T 14-10-2018 A4R43_35640 ab6eeedd2654497124a675251c56e3fd 301 Pfam PF03466 LysR substrate binding domain 101 300 9.1E-50 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_35640 ab6eeedd2654497124a675251c56e3fd 301 SUPERFAMILY SSF46785 17 123 1.47E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_35640 ab6eeedd2654497124a675251c56e3fd 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 74 8.0E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_35640 ab6eeedd2654497124a675251c56e3fd 301 Gene3D G3DSA:3.40.190.290 102 301 3.8E-54 T 14-10-2018 A4R43_35640 ab6eeedd2654497124a675251c56e3fd 301 Gene3D G3DSA:1.10.10.10 15 100 3.0E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 296 304 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 SUPERFAMILY SSF54292 242 340 1.15E-19 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 Gene3D G3DSA:3.10.20.30 256 342 5.2E-18 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 SUPERFAMILY SSF52343 133 256 1.57E-26 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 PRINTS PR00409 Phthalate dioxygenase reductase family signature 80 92 1.8E-12 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 PRINTS PR00409 Phthalate dioxygenase reductase family signature 70 80 1.8E-12 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 PRINTS PR00409 Phthalate dioxygenase reductase family signature 220 228 1.8E-12 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 PRINTS PR00409 Phthalate dioxygenase reductase family signature 171 180 1.8E-12 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 PRINTS PR00409 Phthalate dioxygenase reductase family signature 92 106 1.8E-12 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 269 334 6.0E-10 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 Gene3D G3DSA:2.40.30.10 44 136 1.8E-20 T 14-10-2018 A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 Gene3D G3DSA:3.40.50.80 140 251 3.4E-22 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_13070 38148aa3d22f3b6438b8d9d31533fb99 342 SUPERFAMILY SSF63380 47 135 1.29E-19 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 SUPERFAMILY SSF51905 9 372 3.46E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 Pfam PF01494 FAD binding domain 9 343 1.1E-55 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 3.2E-30 T 14-10-2018 A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 3.2E-30 T 14-10-2018 A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 3.2E-30 T 14-10-2018 A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 3.2E-30 T 14-10-2018 A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 331 3.2E-30 T 14-10-2018 A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 3.2E-30 T 14-10-2018 A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 Gene3D G3DSA:3.50.50.60 10 343 1.1E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13100 4cd1ca1198dca6b0f6c20d8258af8d06 528 Gene3D G3DSA:3.30.70.2450 184 269 1.1E-85 T 14-10-2018 A4R43_01395 3ae48085f390b798557c34a5a894b377 132 Pfam PF07498 Rho termination factor, N-terminal domain 95 121 2.6E-5 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A4R43_01395 3ae48085f390b798557c34a5a894b377 132 Gene3D G3DSA:1.10.1740.70 2 62 8.3E-7 T 14-10-2018 A4R43_01395 3ae48085f390b798557c34a5a894b377 132 Pfam PF06150 ChaB 7 61 6.1E-17 T 14-10-2018 IPR009317 ChaB A4R43_01395 3ae48085f390b798557c34a5a894b377 132 SUPERFAMILY SSF140376 3 62 3.66E-15 T 14-10-2018 IPR037205 ChaB superfamily A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.3E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 SUPERFAMILY SSF50249 1 65 9.0E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 PIRSF PIRSF002599 1 66 2.9E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 14-10-2018 IPR019844 Cold-shock conserved site A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 PRINTS PR00050 Cold shock protein signature 39 57 1.7E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 PRINTS PR00050 Cold shock protein signature 4 19 1.7E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 PRINTS PR00050 Cold shock protein signature 24 33 1.7E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 Gene3D G3DSA:2.40.50.140 1 65 3.1E-31 T 14-10-2018 A4R43_01550 4bcf2b5985ca18e017b8fbc8c830089e 66 SMART SM00357 3 66 3.0E-29 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 A4R43_02530 b345eb6592b74af53bacc0f065bf24ec 306 SUPERFAMILY SSF160964 15 45 5.62E-5 T 14-10-2018 A4R43_02530 b345eb6592b74af53bacc0f065bf24ec 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 303 1.5E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_02530 b345eb6592b74af53bacc0f065bf24ec 306 SUPERFAMILY SSF161098 62 292 1.05E-57 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_02530 b345eb6592b74af53bacc0f065bf24ec 306 Gene3D G3DSA:1.10.3720.10 58 306 7.6E-64 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 Gene3D G3DSA:3.40.50.720 2 256 1.2E-70 T 14-10-2018 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 10 255 2.0E-105 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 83 100 1.6E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 168 191 1.6E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 207 226 1.6E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 14 31 1.6E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 103 123 1.6E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 233 252 1.6E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 1.5E-54 T 14-10-2018 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 186 0.0047 T 14-10-2018 A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 SUPERFAMILY SSF51735 7 255 6.96E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09935 e901f555d0e92603cd79c2cc2b0501f8 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_26420 c3d937b2179e6cc9c06401678be6440c 199 Gene3D G3DSA:1.10.10.60 3 69 5.8E-18 T 14-10-2018 A4R43_26420 c3d937b2179e6cc9c06401678be6440c 199 SUPERFAMILY SSF48498 86 197 3.86E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_26420 c3d937b2179e6cc9c06401678be6440c 199 Gene3D G3DSA:1.10.357.10 70 199 5.5E-42 T 14-10-2018 A4R43_26420 c3d937b2179e6cc9c06401678be6440c 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_26420 c3d937b2179e6cc9c06401678be6440c 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 3.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_26420 c3d937b2179e6cc9c06401678be6440c 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.6E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_26420 c3d937b2179e6cc9c06401678be6440c 199 SUPERFAMILY SSF46689 7 91 1.4E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_29780 8e6baa8fcb6566a28789aae3a1ae6855 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_29780 8e6baa8fcb6566a28789aae3a1ae6855 539 SUPERFAMILY SSF56801 8 530 1.7E-136 T 14-10-2018 A4R43_29780 8e6baa8fcb6566a28789aae3a1ae6855 539 Gene3D G3DSA:3.40.50.12780 1 430 2.6E-115 T 14-10-2018 A4R43_29780 8e6baa8fcb6566a28789aae3a1ae6855 539 Gene3D G3DSA:3.30.300.310 431 532 2.1E-31 T 14-10-2018 A4R43_29780 8e6baa8fcb6566a28789aae3a1ae6855 539 Pfam PF00501 AMP-binding enzyme 25 435 1.2E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_29780 8e6baa8fcb6566a28789aae3a1ae6855 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 517 1.2E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 Gene3D G3DSA:3.20.20.80 20 327 2.8E-83 T 14-10-2018 A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 SMART SM00637 433 533 1.7E-46 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 41 285 6.3E-33 T 14-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 Pfam PF00041 Fibronectin type III domain 340 414 3.1E-11 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 SUPERFAMILY SSF49265 334 427 1.28E-16 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 SUPERFAMILY SSF49384 428 534 7.67E-33 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 Pfam PF00553 Cellulose binding domain 433 533 1.1E-29 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 Gene3D G3DSA:2.60.40.10 335 425 2.0E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 SUPERFAMILY SSF51445 31 326 1.99E-72 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 SMART SM00060 337 414 4.9E-11 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_06415 cd260d8955ce3094acc0b3157b51a90a 536 Gene3D G3DSA:2.60.40.290 426 536 1.6E-35 T 14-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A4R43_20275 2f1dc757b54af88dc1c991d622ca59c5 187 Gene3D G3DSA:3.40.430.10 2 184 7.5E-34 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_20275 2f1dc757b54af88dc1c991d622ca59c5 187 Pfam PF01872 RibD C-terminal domain 48 180 2.2E-16 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_20275 2f1dc757b54af88dc1c991d622ca59c5 187 SUPERFAMILY SSF53597 5 184 3.01E-22 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 Gene3D G3DSA:3.90.226.10 1 190 7.6E-68 T 14-10-2018 A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 SUPERFAMILY SSF52096 16 191 7.69E-62 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 190 37.985 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 PRINTS PR00127 Clp protease catalytic subunit P signature 108 127 1.1E-41 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 PRINTS PR00127 Clp protease catalytic subunit P signature 16 31 1.1E-41 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 PRINTS PR00127 Clp protease catalytic subunit P signature 87 104 1.1E-41 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 PRINTS PR00127 Clp protease catalytic subunit P signature 56 76 1.1E-41 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 PRINTS PR00127 Clp protease catalytic subunit P signature 165 184 1.1E-41 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_00110 380a3b1f7e1ac4420bc061cc63050abf 195 Pfam PF00574 Clp protease 15 188 3.3E-73 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4R43_27150 2ad3caf8341c73c276ade503335aa707 242 Gene3D G3DSA:3.90.79.10 28 203 5.0E-39 T 14-10-2018 A4R43_27150 2ad3caf8341c73c276ade503335aa707 242 SUPERFAMILY SSF55811 34 199 2.98E-29 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_27150 2ad3caf8341c73c276ade503335aa707 242 Pfam PF00293 NUDIX domain 43 176 3.2E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_10465 008ca0f1fbb084304974c2e247944712 406 Pfam PF07724 AAA domain (Cdc48 subfamily) 112 297 4.3E-43 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_10465 008ca0f1fbb084304974c2e247944712 406 Gene3D G3DSA:3.30.50.30 2 46 4.4E-16 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily A4R43_10465 008ca0f1fbb084304974c2e247944712 406 SUPERFAMILY SSF57716 7 43 8.41E-8 T 14-10-2018 A4R43_10465 008ca0f1fbb084304974c2e247944712 406 SUPERFAMILY SSF52540 53 384 2.15E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10465 008ca0f1fbb084304974c2e247944712 406 SMART SM00994 6 46 1.9E-16 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4R43_10465 008ca0f1fbb084304974c2e247944712 406 Gene3D G3DSA:3.40.50.300 48 301 1.2E-94 T 14-10-2018 A4R43_10465 008ca0f1fbb084304974c2e247944712 406 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 5 402 47.419 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4R43_10465 008ca0f1fbb084304974c2e247944712 406 Pfam PF06689 ClpX C4-type zinc finger 8 45 1.3E-17 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4R43_10465 008ca0f1fbb084304974c2e247944712 406 SMART SM00382 111 273 5.3E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10465 008ca0f1fbb084304974c2e247944712 406 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 6 397 9.3E-160 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4R43_10465 008ca0f1fbb084304974c2e247944712 406 SMART SM01086 304 398 1.2E-23 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_10465 008ca0f1fbb084304974c2e247944712 406 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 304 382 1.8E-12 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_10465 008ca0f1fbb084304974c2e247944712 406 Gene3D G3DSA:1.10.8.60 303 404 6.2E-31 T 14-10-2018 A4R43_17545 79dff6ea840a21e419591a289a868659 398 Pfam PF00082 Subtilase family 63 306 4.2E-22 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_17545 79dff6ea840a21e419591a289a868659 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 103 116 1.3E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_17545 79dff6ea840a21e419591a289a868659 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 63 82 1.3E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_17545 79dff6ea840a21e419591a289a868659 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 266 282 1.3E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_17545 79dff6ea840a21e419591a289a868659 398 Gene3D G3DSA:3.40.50.200 17 331 4.8E-52 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_17545 79dff6ea840a21e419591a289a868659 398 SUPERFAMILY SSF52743 42 327 1.57E-48 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_07630 e1828e29c2611ef64a2159c3b3d27794 385 Gene3D G3DSA:3.20.20.70 2 385 1.8E-98 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_07630 e1828e29c2611ef64a2159c3b3d27794 385 SUPERFAMILY SSF51395 4 378 2.93E-92 T 14-10-2018 A4R43_07630 e1828e29c2611ef64a2159c3b3d27794 385 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 232 1.0E-40 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4R43_30555 f9b2f732e5754a593d29e1da3bf2deca 638 SUPERFAMILY SSF160424 147 279 1.57E-14 T 14-10-2018 IPR036170 Probable antitoxin YezG superfamily A4R43_30555 f9b2f732e5754a593d29e1da3bf2deca 638 Pfam PF14021 Tuberculosis necrotizing toxin 552 635 9.7E-17 T 14-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 A4R43_16865 2acb555e1d2263de5809f5bf1adb6184 179 Gene3D G3DSA:1.20.120.530 16 153 3.1E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_16865 2acb555e1d2263de5809f5bf1adb6184 179 Pfam PF07729 FCD domain 22 143 5.5E-25 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_16865 2acb555e1d2263de5809f5bf1adb6184 179 SUPERFAMILY SSF48008 18 151 1.05E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_16865 2acb555e1d2263de5809f5bf1adb6184 179 SMART SM00895 22 144 4.7E-20 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1575 1586 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3387 3402 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4042 4053 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.40.50.12780 31 421 4.6E-133 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF56801 2446 3376 1.83E-136 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.559.10 4502 4843 3.7E-99 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF52777 3444 3637 2.89E-44 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.300.30 423 494 9.6E-18 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF56801 30 927 1.15E-151 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.559.10 1018 1357 3.9E-122 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF52777 1006 1188 9.45E-39 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF53335 2976 3123 4.18E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:1.10.1200.10 3350 3434 9.6E-27 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF13193 AMP-binding enzyme C-terminal domain 1842 1908 1.5E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF13193 AMP-binding enzyme C-terminal domain 4300 4391 1.6E-7 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF52777 2210 2448 1.67E-51 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2636 2647 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00668 Condensation domain 3449 3883 2.7E-81 T 14-10-2018 IPR001242 Condensation domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00668 Condensation domain 1008 1425 3.2E-75 T 14-10-2018 IPR001242 Condensation domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00668 Condensation domain 2030 2464 4.3E-70 T 14-10-2018 IPR001242 Condensation domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00668 Condensation domain 4500 4904 2.6E-52 T 14-10-2018 IPR001242 Condensation domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00501 AMP-binding enzyme 38 429 4.3E-96 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00501 AMP-binding enzyme 2484 2898 1.1E-91 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00501 AMP-binding enzyme 3903 4292 2.2E-93 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00501 AMP-binding enzyme 1444 1834 2.6E-100 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.40.50.12780 2472 2891 2.6E-122 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.40.50.12780 1430 1828 5.3E-149 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.40.50.12780 3890 4286 1.4E-131 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF52777 4503 4664 6.0E-28 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.559.10 2035 2396 3.9E-119 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF52777 1173 1409 4.78E-57 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:1.10.1200.10 4403 4491 5.1E-26 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:1.10.1200.10 1919 2005 9.3E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 ProSitePatterns PS00455 Putative AMP-binding domain signature. 179 190 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF52777 4668 4900 1.05E-50 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.559.30 3621 3869 1.0E-143 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.300.30 2892 2978 2.7E-13 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.559.30 4668 4902 3.7E-99 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF13649 Methyltransferase domain 3017 3116 3.5E-9 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.40.50.1820 903 1017 6.2E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00550 Phosphopantetheine attachment site 4418 4481 2.9E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00550 Phosphopantetheine attachment site 1934 1995 2.6E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00550 Phosphopantetheine attachment site 3365 3425 4.8E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF00550 Phosphopantetheine attachment site 917 975 8.9E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Pfam PF08241 Methyltransferase domain 541 640 1.4E-10 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.559.30 1174 1422 3.9E-122 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.559.30 2211 2460 3.9E-119 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF47336 1925 1995 3.8E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 59 453 1.3E-125 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3924 4316 3.5E-125 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1465 1858 4.2E-135 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2505 2922 1.2E-107 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4440 4455 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF56801 3865 4429 6.93E-146 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF47336 3356 3425 1.09E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SMART SM00823 Phosphopantetheine attachment site 3363 3432 1.5E-7 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SMART SM00823 Phosphopantetheine attachment site 1932 2002 0.001 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SMART SM00823 Phosphopantetheine attachment site 4416 4485 4.5E-7 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SMART SM00823 Phosphopantetheine attachment site 914 982 9.8E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF52777 2026 2204 8.45E-39 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF52777 3625 3891 2.45E-57 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.300.30 3259 3349 2.1E-13 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.300.30 1829 1918 5.7E-28 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.300.30 813 901 1.2E-12 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.300.30 4287 4402 2.0E-31 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF47336 907 976 1.31E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.40.50.150 2983 3152 1.0E-32 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.40.50.150 518 680 5.9E-29 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF56801 1407 1945 9.16E-156 T 14-10-2018 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF47336 4410 4482 1.57E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 Gene3D G3DSA:3.30.559.10 3450 3811 1.0E-143 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_37835 cc4719e180cf0fa6f2ff4faa33d1889e 4907 SUPERFAMILY SSF53335 504 655 3.38E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 108 118 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 Gene3D G3DSA:3.40.50.200 22 332 4.7E-80 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 SUPERFAMILY SSF52743 45 329 1.7E-72 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 270 280 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 Pfam PF00082 Subtilase family 63 320 1.4E-35 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 68 79 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 53 392 7.1E-92 T 14-10-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 104 117 1.7E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 63 82 1.7E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_12285 883b78dcc30158c5e29f19a69d290151 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 269 285 1.7E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 174 188 9.2E-12 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 149 161 9.2E-12 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 309 322 9.2E-12 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 250 258 9.2E-12 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 174 196 - T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 SUPERFAMILY SSF53187 122 420 4.3E-79 T 14-10-2018 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 SMART SM00631 123 407 1.7E-94 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 Pfam PF00246 Zinc carboxypeptidase 131 405 2.0E-66 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 312 322 - T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26925 27ea75176bb8a1a9134e16a1660e540b 421 Gene3D G3DSA:3.40.630.10 116 421 4.7E-101 T 14-10-2018 A4R43_18045 4a949aadcf02904afbfbe2950d03aa19 211 Pfam PF04973 Nicotinamide mononucleotide transporter 17 196 2.2E-40 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 A4R43_21275 f96bedfe1696e2b6190e4640f3a32b4d 181 Gene3D G3DSA:3.40.390.10 32 168 8.1E-38 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A4R43_21275 f96bedfe1696e2b6190e4640f3a32b4d 181 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 39 65 3.4E-12 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_21275 f96bedfe1696e2b6190e4640f3a32b4d 181 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 153 167 3.4E-12 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_21275 f96bedfe1696e2b6190e4640f3a32b4d 181 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 126 150 3.4E-12 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_21275 f96bedfe1696e2b6190e4640f3a32b4d 181 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 40 161 1.0E-33 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_21275 f96bedfe1696e2b6190e4640f3a32b4d 181 SUPERFAMILY SSF55486 33 165 1.24E-20 T 14-10-2018 A4R43_21275 f96bedfe1696e2b6190e4640f3a32b4d 181 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 32 168 1.6E-22 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_21275 f96bedfe1696e2b6190e4640f3a32b4d 181 SMART SM00235 26 167 0.0019 T 14-10-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 255 430 7.5E-52 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 33 138 2.0E-19 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 SUPERFAMILY SSF51735 251 430 4.72E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 Gene3D G3DSA:1.10.1040.10 144 245 1.3E-23 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 SUPERFAMILY SSF48179 140 236 4.59E-24 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 Gene3D G3DSA:1.10.1040.10 435 530 9.4E-27 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 SUPERFAMILY SSF51735 1 140 1.23E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 433 527 3.0E-26 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 141 234 3.2E-21 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 SUPERFAMILY SSF48179 433 529 3.23E-26 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 Gene3D G3DSA:3.40.50.720 246 434 1.9E-58 T 14-10-2018 A4R43_19775 d07910876f6569617c6dc97a1b2cdb50 530 Gene3D G3DSA:3.40.50.720 29 143 4.2E-24 T 14-10-2018 A4R43_24070 583db5f1ec64d8e8b82df2e7bc096ad0 336 SUPERFAMILY SSF55021 253 324 5.26E-7 T 14-10-2018 A4R43_24070 583db5f1ec64d8e8b82df2e7bc096ad0 336 SMART SM00382 30 218 3.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_24070 583db5f1ec64d8e8b82df2e7bc096ad0 336 Gene3D G3DSA:3.40.50.300 1 261 6.6E-65 T 14-10-2018 A4R43_24070 583db5f1ec64d8e8b82df2e7bc096ad0 336 Pfam PF00005 ABC transporter 21 169 3.4E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_24070 583db5f1ec64d8e8b82df2e7bc096ad0 336 SUPERFAMILY SSF52540 1 238 1.17E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24070 583db5f1ec64d8e8b82df2e7bc096ad0 336 SMART SM00930 254 327 2.0E-6 T 14-10-2018 IPR018449 NIL domain A4R43_24070 583db5f1ec64d8e8b82df2e7bc096ad0 336 Pfam PF09383 NIL domain 258 325 7.2E-9 T 14-10-2018 IPR018449 NIL domain A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 SUPERFAMILY SSF63380 224 319 5.55E-16 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 Pfam PF01794 Ferric reductase like transmembrane component 57 178 1.3E-13 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 Pfam PF00175 Oxidoreductase NAD-binding domain 331 427 4.4E-9 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 Gene3D G3DSA:2.40.30.10 218 317 1.2E-12 T 14-10-2018 A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 PRINTS PR00410 Phenol hydroxylase reductase family signature 330 349 1.4E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 PRINTS PR00410 Phenol hydroxylase reductase family signature 414 422 1.4E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 PRINTS PR00410 Phenol hydroxylase reductase family signature 314 323 1.4E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 Gene3D G3DSA:3.40.50.80 324 449 1.4E-26 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_11435 0b893bf2d0a321db3c2e931cd3826516 450 SUPERFAMILY SSF52343 310 444 9.04E-30 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_11800 1810d50f781115be7b37fc9543e9d878 335 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 290 1.7E-59 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11800 1810d50f781115be7b37fc9543e9d878 335 Pfam PF02470 MlaD protein 37 109 1.6E-13 T 14-10-2018 IPR003399 Mce/MlaD A4R43_30130 4c2af459e69cc7bfb83f0aba27c6f870 426 Pfam PF02470 MlaD protein 44 119 1.6E-11 T 14-10-2018 IPR003399 Mce/MlaD A4R43_20145 b1ce607982a2b194c16683c6bffa9c60 262 Gene3D G3DSA:3.40.50.620 2 262 1.4E-82 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_20145 b1ce607982a2b194c16683c6bffa9c60 262 SMART SM00893 24 215 9.5E-55 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4R43_20145 b1ce607982a2b194c16683c6bffa9c60 262 SUPERFAMILY SSF52402 3 256 1.26E-72 T 14-10-2018 A4R43_20145 b1ce607982a2b194c16683c6bffa9c60 262 PIRSF PIRSF000090 2 262 1.4E-84 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A4R43_20145 b1ce607982a2b194c16683c6bffa9c60 262 Pfam PF01012 Electron transfer flavoprotein domain 26 211 1.1E-47 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4R43_32495 d2e343fa3197b0b824f8dadac6ab8837 183 Pfam PF04542 Sigma-70 region 2 26 88 7.5E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_32495 d2e343fa3197b0b824f8dadac6ab8837 183 Pfam PF08281 Sigma-70, region 4 110 163 1.3E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_32495 d2e343fa3197b0b824f8dadac6ab8837 183 Gene3D G3DSA:1.10.10.10 90 169 3.3E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32495 d2e343fa3197b0b824f8dadac6ab8837 183 Gene3D G3DSA:1.10.1740.10 12 89 1.6E-9 T 14-10-2018 A4R43_32495 d2e343fa3197b0b824f8dadac6ab8837 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 167 9.8E-22 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_32495 d2e343fa3197b0b824f8dadac6ab8837 183 SUPERFAMILY SSF88659 108 168 4.49E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_32495 d2e343fa3197b0b824f8dadac6ab8837 183 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 14 167 5.5E-47 T 14-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4R43_32495 d2e343fa3197b0b824f8dadac6ab8837 183 SUPERFAMILY SSF88946 16 104 3.14E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 Gene3D G3DSA:2.40.10.10 192 264 4.6E-23 T 14-10-2018 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 Pfam PF02983 Alpha-lytic protease prodomain 122 175 7.4E-8 T 14-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 Gene3D G3DSA:2.40.10.10 265 353 4.7E-28 T 14-10-2018 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 PIRSF PIRSF001134 6 366 1.6E-81 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 SUPERFAMILY SSF50494 198 359 4.02E-26 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 350 2.6E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 218 232 2.6E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 272 292 2.6E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 293 310 2.6E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_33505 6201199ce72158c9cd989343dc43ac58 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 312 335 2.6E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11135 1169d66b49b3b84572cdc0bd60d8ad00 327 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 322 55.658 T 14-10-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 A4R43_11135 1169d66b49b3b84572cdc0bd60d8ad00 327 PIRSF PIRSF018005 2 323 1.7E-126 T 14-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 A4R43_11135 1169d66b49b3b84572cdc0bd60d8ad00 327 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 319 2.6E-113 T 14-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 A4R43_11135 1169d66b49b3b84572cdc0bd60d8ad00 327 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 19 321 2.0E-113 T 14-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent A4R43_11135 1169d66b49b3b84572cdc0bd60d8ad00 327 SUPERFAMILY SSF53335 31 211 1.22E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_11135 1169d66b49b3b84572cdc0bd60d8ad00 327 Gene3D G3DSA:3.40.50.150 46 220 5.0E-57 T 14-10-2018 A4R43_11135 1169d66b49b3b84572cdc0bd60d8ad00 327 Gene3D G3DSA:3.40.50.150 268 322 1.1E-5 T 14-10-2018 A4R43_37290 6210fb32246bdf806cc17a9e0fd56d1f 278 SUPERFAMILY SSF51197 18 259 1.01E-43 T 14-10-2018 A4R43_37290 6210fb32246bdf806cc17a9e0fd56d1f 278 Gene3D G3DSA:2.60.120.620 2 273 7.5E-74 T 14-10-2018 A4R43_37290 6210fb32246bdf806cc17a9e0fd56d1f 278 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 21 216 6.1E-25 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 Pfam PF11798 IMS family HHH motif 202 231 1.0E-7 T 14-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 Gene3D G3DSA:2.30.40.20 55 106 3.5E-55 T 14-10-2018 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 Pfam PF00817 impB/mucB/samB family 41 187 8.6E-45 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 Gene3D G3DSA:1.10.150.20 201 270 5.1E-21 T 14-10-2018 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 Gene3D G3DSA:3.30.1490.100 275 382 9.8E-25 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 SUPERFAMILY SSF100879 275 372 7.06E-25 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 Hamap MF_01113 DNA polymerase IV [dinB]. 35 385 35.194 T 14-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 Gene3D G3DSA:3.30.70.270 39 198 3.5E-55 T 14-10-2018 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 Pfam PF11799 impB/mucB/samB family C-terminal domain 268 381 8.7E-18 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_41360 96eaf3e3489873135af5e62cc899c0d9 422 SUPERFAMILY SSF56672 37 269 6.4E-80 T 14-10-2018 A4R43_10415 e89059c56734efeab98a0ae924fd9687 328 Gene3D G3DSA:3.40.50.2300 143 283 3.4E-99 T 14-10-2018 A4R43_10415 e89059c56734efeab98a0ae924fd9687 328 Pfam PF13407 Periplasmic binding protein domain 43 301 5.4E-48 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_10415 e89059c56734efeab98a0ae924fd9687 328 SUPERFAMILY SSF53822 39 317 1.32E-71 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_10415 e89059c56734efeab98a0ae924fd9687 328 Gene3D G3DSA:3.40.50.2300 42 300 3.4E-99 T 14-10-2018 A4R43_34310 250277b8dc35023fa6258980a0a6dec1 106 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 7 100 18.365 T 14-10-2018 IPR003482 Transcription factor WhiB A4R43_34310 250277b8dc35023fa6258980a0a6dec1 106 Pfam PF02467 Transcription factor WhiB 23 92 1.5E-22 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain A4R43_25680 f182dcfc19eb37f30737b97aa31095d3 375 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 14 373 4.1E-194 T 14-10-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 A4R43_25680 f182dcfc19eb37f30737b97aa31095d3 375 Gene3D G3DSA:3.40.640.10 30 269 1.6E-55 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_25680 f182dcfc19eb37f30737b97aa31095d3 375 SUPERFAMILY SSF53383 15 373 6.33E-73 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_25680 f182dcfc19eb37f30737b97aa31095d3 375 Gene3D G3DSA:3.90.1150.10 270 374 3.5E-40 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_25680 f182dcfc19eb37f30737b97aa31095d3 375 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 8 374 23.712 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4R43_25680 f182dcfc19eb37f30737b97aa31095d3 375 Pfam PF00266 Aminotransferase class-V 142 333 3.3E-11 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_25680 f182dcfc19eb37f30737b97aa31095d3 375 PIRSF PIRSF000525 4 375 6.4E-77 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4R43_00925 bd4e759b43e77522d80a78b466ea9034 266 SUPERFAMILY SSF52317 55 237 2.65E-37 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_00925 bd4e759b43e77522d80a78b466ea9034 266 Pfam PF01965 DJ-1/PfpI family 55 216 1.2E-21 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_00925 bd4e759b43e77522d80a78b466ea9034 266 Gene3D G3DSA:3.40.50.880 35 266 1.5E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 SMART SM00421 745 802 2.7E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 Pfam PF00196 Bacterial regulatory proteins, luxR family 747 801 7.7E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 Gene3D G3DSA:1.25.40.10 272 604 2.4E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 ProSitePatterns PS00622 LuxR-type HTH domain signature. 762 789 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 778 790 1.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 748 762 1.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 762 778 1.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 Gene3D G3DSA:1.10.10.10 688 812 1.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 SUPERFAMILY SSF46894 741 804 3.1E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_10930 a9a2fafbba95cd336d1ce74eceb7f4b6 814 SUPERFAMILY SSF48452 370 556 2.37E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_08005 269f13a5f1a1d94d84afc3887cb26195 494 Gene3D G3DSA:3.30.750.24 393 488 6.1E-28 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_08005 269f13a5f1a1d94d84afc3887cb26195 494 SUPERFAMILY SSF52091 405 479 1.49E-11 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_08005 269f13a5f1a1d94d84afc3887cb26195 494 Pfam PF00916 Sulfate permease family 22 147 1.2E-19 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4R43_08005 269f13a5f1a1d94d84afc3887cb26195 494 Pfam PF00916 Sulfate permease family 170 361 1.2E-25 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4R43_08005 269f13a5f1a1d94d84afc3887cb26195 494 Pfam PF01740 STAS domain 408 478 2.9E-6 T 14-10-2018 IPR002645 STAS domain A4R43_01705 b52089124854348c444977ad743fc726 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 52 5.7E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01705 b52089124854348c444977ad743fc726 222 Gene3D G3DSA:1.10.10.60 3 51 1.3E-17 T 14-10-2018 A4R43_01705 b52089124854348c444977ad743fc726 222 SUPERFAMILY SSF46689 5 69 4.58E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01705 b52089124854348c444977ad743fc726 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 7.7E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01705 b52089124854348c444977ad743fc726 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 7.7E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01705 b52089124854348c444977ad743fc726 222 Gene3D G3DSA:1.10.357.10 52 185 2.4E-23 T 14-10-2018 A4R43_32740 daa152f79b33a8a12019b0d1ba58479a 392 Gene3D G3DSA:2.40.440.10 244 379 1.2E-86 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_32740 daa152f79b33a8a12019b0d1ba58479a 392 Pfam PF03734 L,D-transpeptidase catalytic domain 243 363 3.0E-15 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4R43_32740 daa152f79b33a8a12019b0d1ba58479a 392 SUPERFAMILY SSF141523 241 363 3.27E-22 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_32740 daa152f79b33a8a12019b0d1ba58479a 392 Gene3D G3DSA:2.60.40.3780 44 140 7.1E-26 T 14-10-2018 A4R43_32740 daa152f79b33a8a12019b0d1ba58479a 392 Gene3D G3DSA:2.60.40.3710 150 391 1.2E-86 T 14-10-2018 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 SUPERFAMILY SSF52440 1 113 1.51E-44 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 Pfam PF00364 Biotin-requiring enzyme 584 647 3.2E-17 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 139 313 1.1E-63 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 SUPERFAMILY SSF51230 580 648 5.37E-21 T 14-10-2018 IPR011053 Single hybrid motif A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 Gene3D G3DSA:3.30.470.130 1 445 9.1E-182 T 14-10-2018 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 5.1E-41 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 SUPERFAMILY SSF51246 320 442 4.97E-36 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 SMART SM00878 325 440 8.5E-47 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 Pfam PF02785 Biotin carboxylase C-terminal domain 325 439 2.0E-31 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 Gene3D G3DSA:2.40.50.100 583 652 2.1E-22 T 14-10-2018 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 144 158 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 SUPERFAMILY SSF56059 83 321 1.71E-61 T 14-10-2018 A4R43_05225 cf6daf048a9954c5c9980cc7e4c82d17 653 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 277 284 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_18235 bbdb59dd55cc5b4aa37fca1b8175c36a 388 Gene3D G3DSA:3.40.640.10 58 288 1.7E-113 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_18235 bbdb59dd55cc5b4aa37fca1b8175c36a 388 SUPERFAMILY SSF53383 17 385 1.09E-89 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_18235 bbdb59dd55cc5b4aa37fca1b8175c36a 388 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A4R43_18235 bbdb59dd55cc5b4aa37fca1b8175c36a 388 Gene3D G3DSA:3.90.1150.10 44 374 1.7E-113 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_18235 bbdb59dd55cc5b4aa37fca1b8175c36a 388 Pfam PF00155 Aminotransferase class I and II 43 382 9.3E-57 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 Gene3D G3DSA:1.10.287.110 7 131 1.4E-28 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 Gene3D G3DSA:2.60.260.20 132 200 4.5E-19 T 14-10-2018 A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 Pfam PF00226 DnaJ domain 10 72 1.7E-24 T 14-10-2018 IPR001623 DnaJ domain A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 Pfam PF01556 DnaJ C terminal domain 136 280 1.8E-30 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 PRINTS PR00625 DnaJ domain signature 12 30 2.2E-23 T 14-10-2018 IPR001623 DnaJ domain A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 PRINTS PR00625 DnaJ domain signature 30 45 2.2E-23 T 14-10-2018 IPR001623 DnaJ domain A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 PRINTS PR00625 DnaJ domain signature 47 67 2.2E-23 T 14-10-2018 IPR001623 DnaJ domain A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 PRINTS PR00625 DnaJ domain signature 67 86 2.2E-23 T 14-10-2018 IPR001623 DnaJ domain A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 SUPERFAMILY SSF49493 129 209 7.19E-16 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 SUPERFAMILY SSF46565 9 109 1.09E-28 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 SMART SM00271 9 67 7.9E-27 T 14-10-2018 IPR001623 DnaJ domain A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 SUPERFAMILY SSF49493 206 291 2.88E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4R43_12770 76ef7d254cb4cc96186117e1e5139408 309 Gene3D G3DSA:2.60.260.20 202 304 1.9E-22 T 14-10-2018 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 Gene3D G3DSA:3.30.1360.40 250 350 2.4E-188 T 14-10-2018 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 SUPERFAMILY SSF56719 46 504 8.89E-159 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 685 727 3.3 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 750 769 0.03 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 576 598 4.2 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 SUPERFAMILY SSF101904 524 789 3.14E-41 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 Gene3D G3DSA:1.10.268.10 387 475 2.4E-188 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 Gene3D G3DSA:3.90.199.10 47 503 2.4E-188 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 SMART SM00434 26 482 8.7E-235 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 47 487 1.2E-145 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_37435 fa8adb9cf359afe9d32d8ef4b0858290 828 Gene3D G3DSA:2.120.10.90 524 786 7.3E-48 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4R43_37810 573856310fb055bef98348222f1eb857 140 SMART SM00357 3 66 1.4E-10 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 A4R43_37810 573856310fb055bef98348222f1eb857 140 SUPERFAMILY SSF50249 3 65 3.18E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_37810 573856310fb055bef98348222f1eb857 140 Gene3D G3DSA:2.40.50.140 1 91 1.7E-18 T 14-10-2018 A4R43_37810 573856310fb055bef98348222f1eb857 140 PRINTS PR00050 Cold shock protein signature 25 34 9.3E-7 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_37810 573856310fb055bef98348222f1eb857 140 PRINTS PR00050 Cold shock protein signature 4 19 9.3E-7 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_37810 573856310fb055bef98348222f1eb857 140 PRINTS PR00050 Cold shock protein signature 39 57 9.3E-7 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_37810 573856310fb055bef98348222f1eb857 140 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 1.1E-14 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_19125 5696f42fc0d2628b577d2b0229639759 603 Gene3D G3DSA:1.10.3810.10 64 255 2.4E-54 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_19125 5696f42fc0d2628b577d2b0229639759 603 Gene3D G3DSA:3.40.710.10 274 603 1.2E-78 T 14-10-2018 A4R43_19125 5696f42fc0d2628b577d2b0229639759 603 SUPERFAMILY SSF53955 62 256 2.22E-53 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_19125 5696f42fc0d2628b577d2b0229639759 603 SUPERFAMILY SSF56601 226 601 1.06E-58 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_19125 5696f42fc0d2628b577d2b0229639759 603 Pfam PF00912 Transglycosylase 76 240 2.4E-47 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_19125 5696f42fc0d2628b577d2b0229639759 603 Pfam PF00905 Penicillin binding protein transpeptidase domain 363 546 1.4E-14 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SUPERFAMILY SSF58104 580 703 5.75E-10 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:1.10.287.130 916 1015 2.7E-24 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:3.40.50.12740 1338 1459 6.2E-40 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00304 284 336 4.7E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00304 376 428 1.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00304 468 520 4.5E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00304 652 704 1.4E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00304 100 152 1.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00304 192 244 3.7E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00304 560 612 1.7E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00304 8 60 0.15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1102 1116 1.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1137 1155 1.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1161 1174 1.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1120 1130 1.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:3.40.50.2300 1198 1320 1.9E-7 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SUPERFAMILY SSF47384 934 1019 5.49E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Pfam PF00672 HAMP domain 474 516 3.1E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Pfam PF00672 HAMP domain 653 701 3.3E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Pfam PF00672 HAMP domain 287 331 1.1E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SUPERFAMILY SSF58104 304 576 3.01E-17 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:3.30.450.40 705 866 1.4E-20 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00065 728 878 2.7E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 950 1017 7.6E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00388 949 1017 1.3E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Pfam PF00072 Response regulator receiver domain 1341 1451 3.4E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SUPERFAMILY SSF58104 120 295 1.57E-13 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Pfam PF13185 GAF domain 727 862 1.0E-16 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:1.10.8.500 469 526 1.9E-6 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:1.10.8.500 286 342 8.4E-9 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:1.10.8.500 377 434 5.0E-9 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:1.10.8.500 195 250 2.0E-8 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SUPERFAMILY SSF55781 691 862 5.33E-28 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00448 1339 1453 2.0E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SUPERFAMILY SSF55874 1006 1177 2.49E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1064 1175 3.5E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:3.30.565.10 1016 1179 2.1E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:1.20.1480.50 650 704 2.4E-5 T 14-10-2018 A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SMART SM00387 1064 1177 6.2E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:2.60.120.260 92 192 4.0E-8 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 Gene3D G3DSA:2.60.120.260 552 649 4.0E-8 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SUPERFAMILY SSF52172 1210 1280 8.25E-6 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_13715 4afd2099a6580ba92a28f7a9a5ae5e8f 1459 SUPERFAMILY SSF52172 1334 1459 1.12E-36 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Pfam PF00501 AMP-binding enzyme 462 851 1.8E-86 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 SUPERFAMILY SSF47336 951 1018 5.04E-11 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Gene3D G3DSA:3.30.559.30 185 437 1.4E-114 T 14-10-2018 A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 483 875 2.3E-115 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Gene3D G3DSA:3.40.50.12780 452 845 1.3E-125 T 14-10-2018 A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Gene3D G3DSA:3.30.559.10 8 372 1.4E-114 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Gene3D G3DSA:3.30.300.30 846 946 1.7E-32 T 14-10-2018 A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 SUPERFAMILY SSF52777 8 183 3.11E-45 T 14-10-2018 A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Gene3D G3DSA:3.40.50.1820 947 1031 7.9E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Pfam PF00550 Phosphopantetheine attachment site 959 1017 7.0E-5 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Pfam PF00668 Condensation domain 3 439 4.1E-64 T 14-10-2018 IPR001242 Condensation domain A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 SUPERFAMILY SSF56801 420 969 1.57E-142 T 14-10-2018 A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 SUPERFAMILY SSF52777 185 427 4.78E-50 T 14-10-2018 A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 Pfam PF13193 AMP-binding enzyme C-terminal domain 859 933 7.6E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_12560 59fffce9817adefb79b734c78ea8abd3 1034 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_40740 e54c1f1e15417896f32b61c75954cfdc 418 SUPERFAMILY SSF53474 109 371 9.12E-12 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40740 e54c1f1e15417896f32b61c75954cfdc 418 Pfam PF07519 Tannase and feruloyl esterase 93 200 1.1E-9 T 14-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 A4R43_40740 e54c1f1e15417896f32b61c75954cfdc 418 Pfam PF10605 3HB-oligomer hydrolase (3HBOH) 305 412 7.7E-8 T 14-10-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 A4R43_17415 06665f56aa9463ff5713644d2b0c8cce 228 SUPERFAMILY SSF52518 24 222 5.64E-46 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_17415 06665f56aa9463ff5713644d2b0c8cce 228 Gene3D G3DSA:3.40.50.970 13 225 2.7E-48 T 14-10-2018 A4R43_17415 06665f56aa9463ff5713644d2b0c8cce 228 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 23 210 3.3E-21 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_20445 10fc5b154030c58a3e3bb1f06b24b52b 94 Gene3D G3DSA:3.20.20.220 1 63 2.5E-5 T 14-10-2018 A4R43_20445 10fc5b154030c58a3e3bb1f06b24b52b 94 Pfam PF02219 Methylenetetrahydrofolate reductase 2 44 1.5E-5 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A4R43_20445 10fc5b154030c58a3e3bb1f06b24b52b 94 SUPERFAMILY SSF51730 1 44 6.67E-7 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like A4R43_00255 903cf078124d2356061b81fa0feb41ae 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 314 3.4E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_38285 c1ab6456af531c2036b99e089261a2a8 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 7.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38285 c1ab6456af531c2036b99e089261a2a8 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 7.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38285 c1ab6456af531c2036b99e089261a2a8 206 Gene3D G3DSA:1.10.357.10 6 204 4.9E-46 T 14-10-2018 A4R43_38285 c1ab6456af531c2036b99e089261a2a8 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 2.1E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38285 c1ab6456af531c2036b99e089261a2a8 206 SUPERFAMILY SSF46689 7 76 4.31E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_18035 b3e9476e6684aa502be6cf46a865ca52 403 Pfam PF01070 FMN-dependent dehydrogenase 43 400 3.8E-130 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A4R43_18035 b3e9476e6684aa502be6cf46a865ca52 403 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 298 304 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 A4R43_18035 b3e9476e6684aa502be6cf46a865ca52 403 PIRSF PIRSF000138 19 403 3.7E-128 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 A4R43_18035 b3e9476e6684aa502be6cf46a865ca52 403 SUPERFAMILY SSF51395 33 401 1.73E-100 T 14-10-2018 A4R43_18035 b3e9476e6684aa502be6cf46a865ca52 403 Gene3D G3DSA:3.20.20.70 33 403 5.1E-133 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_41435 9c1c958a15becfcd27a5402f3140a303 316 Gene3D G3DSA:3.30.420.40 8 301 2.2E-57 T 14-10-2018 A4R43_41435 9c1c958a15becfcd27a5402f3140a303 316 SUPERFAMILY SSF53067 6 126 1.42E-22 T 14-10-2018 A4R43_41435 9c1c958a15becfcd27a5402f3140a303 316 Pfam PF02541 Ppx/GppA phosphatase family 34 306 5.8E-45 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4R43_41435 9c1c958a15becfcd27a5402f3140a303 316 Gene3D G3DSA:3.30.420.150 110 294 2.2E-57 T 14-10-2018 A4R43_41435 9c1c958a15becfcd27a5402f3140a303 316 SUPERFAMILY SSF53067 130 306 7.77E-23 T 14-10-2018 A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 Gene3D G3DSA:1.25.60.10 167 278 1.3E-23 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 Pfam PF03448 MgtE intracellular N domain 180 281 1.7E-22 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 SUPERFAMILY SSF50346 10 89 4.87E-11 T 14-10-2018 IPR011033 PRC-barrel-like superfamily A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 SUPERFAMILY SSF54631 282 413 9.32E-24 T 14-10-2018 A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 Gene3D G3DSA:3.10.580.10 279 409 5.2E-27 T 14-10-2018 A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 SUPERFAMILY SSF158791 170 279 4.32E-26 T 14-10-2018 A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 Pfam PF00571 CBS domain 357 407 1.8E-4 T 14-10-2018 IPR000644 CBS domain A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 Pfam PF00571 CBS domain 284 345 0.0015 T 14-10-2018 IPR000644 CBS domain A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 SMART SM00116 359 407 0.0051 T 14-10-2018 IPR000644 CBS domain A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 SMART SM00924 180 283 3.8E-29 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A4R43_35685 55eda4f0f92e326ecced701d8214bfa4 433 Pfam PF05239 PRC-barrel domain 7 70 6.3E-6 T 14-10-2018 IPR027275 PRC-barrel domain A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 Gene3D G3DSA:3.40.50.12740 16 229 5.1E-39 T 14-10-2018 A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 222 3.9E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 SMART SM00421 166 223 1.4E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 SUPERFAMILY SSF52172 15 141 1.48E-10 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 ProSitePatterns PS00622 LuxR-type HTH domain signature. 183 210 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 SUPERFAMILY SSF46894 162 228 4.08E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 Pfam PF00072 Response regulator receiver domain 18 128 1.8E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 199 7.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 183 7.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_31230 3c7480ace11c1f0c20f0e9760f61b897 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 211 7.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20055 df26f48934cce6a1b1c3c12770b52776 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.7E-17 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4R43_20055 df26f48934cce6a1b1c3c12770b52776 98 Gene3D G3DSA:1.10.20.60 2 94 7.4E-24 T 14-10-2018 A4R43_20055 df26f48934cce6a1b1c3c12770b52776 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 6.6E-25 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4R43_20055 df26f48934cce6a1b1c3c12770b52776 98 SUPERFAMILY SSF141000 4 94 7.19E-28 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 A4R43_20055 df26f48934cce6a1b1c3c12770b52776 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 24.486 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4R43_04155 37f5a7a377015b0155f4a0be2e6c44eb 204 SUPERFAMILY SSF55469 21 201 4.06E-39 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_04155 37f5a7a377015b0155f4a0be2e6c44eb 204 Pfam PF00881 Nitroreductase family 23 182 8.9E-15 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4R43_04155 37f5a7a377015b0155f4a0be2e6c44eb 204 Gene3D G3DSA:3.40.109.10 15 203 3.4E-27 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 9016 9251 1.74E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF55048 10024 10083 1.02E-5 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 2705 2881 5.9E-20 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF55048 5464 5529 1.96E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF52151 542 826 1.57E-67 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.50.720 7320 7807 5.9E-151 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.50.720 10257 10764 1.5E-156 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.50.720 8772 9266 6.4E-155 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF47336 9292 9377 1.19E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF52151 5339 5626 4.45E-65 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF08990 Erythronolide synthase docking 7 30 3.3E-6 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF47336 1588 1703 1.57E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF52151 3743 4018 2.01E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 9902 10195 6.9E-104 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2186 2450 1.2E-102 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8427 8711 1.8E-114 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 838 1.5E-113 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6967 7260 7.5E-105 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3746 4010 5.7E-99 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5343 5638 6.2E-114 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4987 5003 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.30.70.3290 3682 4055 8.8E-128 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7862 7877 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF53901 33 395 2.0E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF53901 1684 2054 4.36E-105 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF08659 KR domain 2890 3054 4.8E-55 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF08659 KR domain 4468 4630 2.4E-50 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF08659 KR domain 10513 10689 1.8E-54 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF08659 KR domain 6105 6268 1.0E-51 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF08659 KR domain 1329 1490 6.3E-45 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF08659 KR domain 9017 9194 1.3E-58 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF08659 KR domain 7560 7733 1.3E-50 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF52151 6965 7252 5.23E-66 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:1.10.1200.10 10776 10870 3.2E-32 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:1.10.1200.10 9280 9373 3.2E-31 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 8083 8099 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00698 Acyl transferase domain 2186 2469 2.9E-44 T 14-10-2018 IPR014043 Acyl transferase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00698 Acyl transferase domain 3746 4029 8.9E-45 T 14-10-2018 IPR014043 Acyl transferase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00698 Acyl transferase domain 8427 8730 7.3E-47 T 14-10-2018 IPR014043 Acyl transferase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00698 Acyl transferase domain 544 857 1.7E-90 T 14-10-2018 IPR014043 Acyl transferase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00698 Acyl transferase domain 5341 5656 4.5E-88 T 14-10-2018 IPR014043 Acyl transferase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00698 Acyl transferase domain 9900 10213 8.5E-77 T 14-10-2018 IPR014043 Acyl transferase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00698 Acyl transferase domain 6965 7279 2.2E-81 T 14-10-2018 IPR014043 Acyl transferase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1620 1635 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.30.70.3290 6902 7307 2.5E-130 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1847 1863 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 2891 3100 1.12E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 6106 6331 7.39E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3178 3193 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.50.720 4336 4696 2.3E-99 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.50.720 5973 6337 6.9E-106 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.50.720 2757 3120 1.7E-110 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.50.720 1176 1561 3.6E-107 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF47336 10789 10877 9.68E-19 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.366.10 9900 10198 1.8E-131 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.366.10 3744 4013 8.8E-128 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.366.10 2184 2453 4.9E-129 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.366.10 543 841 1.7E-152 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.366.10 8425 8714 3.8E-141 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.366.10 6965 7263 2.5E-130 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.366.10 5341 5641 3.4E-157 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.30.70.3290 468 883 1.7E-152 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 188 204 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6395 6410 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 9554 9570 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM01294 6369 6436 2.9E-5 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM01294 1594 1661 1.2E-6 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM01294 9301 9368 4.0E-7 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM01294 10798 10865 6.1E-5 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM01294 4731 4798 2.9E-8 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM01294 7836 7903 1.7E-5 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM01294 3152 3219 2.1E-5 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF47336 4727 4841 1.44E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 9649 9764 2.8E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6714 6829 2.8E-45 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3501 3616 2.4E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 283 398 1.1E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 8178 8293 3.4E-41 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1942 2057 7.3E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5082 5197 3.7E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.10.129.110 5693 5972 2.5E-105 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.10.129.110 892 1175 3.6E-111 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.10.129.110 2496 2756 1.5E-98 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.10.129.110 4063 4335 2.3E-98 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4757 4772 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF55048 2303 2357 2.88E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF47336 7831 7945 2.09E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF55048 8544 8605 1.96E-10 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 10509 10763 2.03E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3247 3493 7.0E-90 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4826 5074 8.7E-93 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 275 2.9E-86 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9395 9641 6.5E-87 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7930 8170 3.8E-82 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6458 6706 1.4E-89 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1688 1934 4.6E-91 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00550 Phosphopantetheine attachment site 1594 1661 2.3E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00550 Phosphopantetheine attachment site 3153 3219 2.6E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00550 Phosphopantetheine attachment site 7837 7903 8.9E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00550 Phosphopantetheine attachment site 9302 9368 5.6E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00550 Phosphopantetheine attachment site 4732 4798 3.4E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00550 Phosphopantetheine attachment site 6370 6436 7.4E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF00550 Phosphopantetheine attachment site 10799 10865 1.1E-8 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.30.70.3290 2123 2495 4.9E-129 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF53901 9391 9762 1.51E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00823 Phosphopantetheine attachment site 1593 1665 1.1E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00823 Phosphopantetheine attachment site 7835 7907 8.0E-27 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00823 Phosphopantetheine attachment site 4730 4802 1.8E-34 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00823 Phosphopantetheine attachment site 3151 3223 1.0E-33 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00823 Phosphopantetheine attachment site 6368 6440 5.0E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00823 Phosphopantetheine attachment site 9300 9372 1.4E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00823 Phosphopantetheine attachment site 10797 10869 6.2E-28 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 7557 7807 1.49E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 9767 9861 1.5E-13 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5200 5298 7.2E-12 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2060 2152 3.8E-13 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6832 6927 2.0E-11 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 8296 8397 1.8E-12 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 401 497 9.5E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3619 3705 1.2E-12 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.30.70.3290 9837 10242 1.8E-131 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.30.70.3290 5265 5684 3.4E-157 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 1175 1317 4.33E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 5918 6096 3.54E-18 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF52151 2183 2452 7.06E-67 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9017 9196 2.3E-60 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2890 3055 8.9E-56 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4468 4632 3.6E-50 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7560 7734 3.3E-44 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1327 1492 9.0E-42 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6105 6270 5.5E-53 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10513 10690 7.8E-45 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 4469 4681 2.63E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 10300 10499 9.05E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF53901 3243 3614 1.8E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 7363 7548 4.72E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.30.70.3290 8363 8758 3.8E-141 T 14-10-2018 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:1.10.1200.10 1576 1668 7.9E-33 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:1.10.1200.10 3134 3225 2.8E-34 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:1.10.1200.10 4712 4804 1.5E-35 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:1.10.1200.10 6351 6443 2.2E-33 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:1.10.1200.10 7817 7910 5.2E-32 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF47336 6363 6473 1.7E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF53901 6455 6828 1.83E-101 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00012 Phosphopantetheine attachment site. 10824 10839 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF14765 Polyketide synthase dehydratase 5704 5970 4.1E-51 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF14765 Polyketide synthase dehydratase 903 1170 3.4E-56 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF14765 Polyketide synthase dehydratase 4074 4331 6.2E-52 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Pfam PF14765 Polyketide synthase dehydratase 2500 2753 2.5E-53 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 1324 1576 9.31E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.47.10 1684 2114 4.3E-186 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.47.10 4822 5253 1.1E-187 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.47.10 3243 3672 1.4E-183 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF52151 9900 10187 3.4E-65 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00012 Phosphopantetheine attachment site. 9327 9342 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF53901 4822 5195 1.44E-105 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF55048 3863 3917 1.83E-6 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00826 903 1064 3.0E-85 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00826 2500 2653 4.0E-73 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00826 4074 4227 1.1E-68 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00826 5704 5863 5.4E-81 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF47336 3145 3262 4.32E-23 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF53901 7926 8292 3.64E-97 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6619 6635 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 4279 4458 2.36E-17 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.47.10 7921 8362 4.5E-176 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.47.10 6449 6890 4.1E-185 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.47.10 28 466 1.0E-184 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 Gene3D G3DSA:3.40.47.10 9386 9829 2.4E-186 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00825 Beta-ketoacyl synthase 4828 5250 1.5E-223 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00825 Beta-ketoacyl synthase 3249 3669 1.1E-215 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00825 Beta-ketoacyl synthase 6460 6882 8.6E-217 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00825 Beta-ketoacyl synthase 1690 2110 3.4E-218 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00825 Beta-ketoacyl synthase 9397 9817 2.8E-217 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00825 Beta-ketoacyl synthase 39 449 1.1E-211 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SMART SM00825 Beta-ketoacyl synthase 7932 8346 7.8E-201 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF51735 8818 9006 4.92E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF52151 8424 8711 6.8E-70 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF55048 666 729 4.05E-10 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3406 3422 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38505 523ddf4262a8f03043798eaeecbb8d63 10948 SUPERFAMILY SSF55048 7089 7148 3.14E-6 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_41580 368566c3b7bdfd5e44ef4bbf235262b4 489 Gene3D G3DSA:3.40.50.880 255 421 8.6E-27 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_41580 368566c3b7bdfd5e44ef4bbf235262b4 489 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 230 1.8E-24 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4R43_41580 368566c3b7bdfd5e44ef4bbf235262b4 489 SUPERFAMILY SSF52317 257 434 1.58E-36 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_41580 368566c3b7bdfd5e44ef4bbf235262b4 489 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 474 3.2E-132 T 14-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A4R43_41580 368566c3b7bdfd5e44ef4bbf235262b4 489 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 256 427 1.4E-38 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A4R43_41580 368566c3b7bdfd5e44ef4bbf235262b4 489 SUPERFAMILY SSF52540 1 237 1.27E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41580 368566c3b7bdfd5e44ef4bbf235262b4 489 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 484 170.925 T 14-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A4R43_41580 368566c3b7bdfd5e44ef4bbf235262b4 489 Gene3D G3DSA:3.40.50.300 3 234 4.2E-52 T 14-10-2018 A4R43_15710 978eaabd8ba6d4dbfba5a97ab5c7e6f0 504 SUPERFAMILY SSF52540 46 387 6.06E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04425 fa6c3bf0ba5023ada7549cde10bd0b46 254 Pfam PF04909 Amidohydrolase 2 250 5.7E-27 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_04425 fa6c3bf0ba5023ada7549cde10bd0b46 254 Gene3D G3DSA:3.20.20.140 1 250 8.7E-43 T 14-10-2018 A4R43_04425 fa6c3bf0ba5023ada7549cde10bd0b46 254 SUPERFAMILY SSF51556 1 250 9.08E-41 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_04765 6097ca9d36be34f652a461772c134ede 400 SUPERFAMILY SSF55973 6 112 6.67E-45 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 Gene3D G3DSA:3.30.300.10 105 389 2.3E-166 T 14-10-2018 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 104 1.0E-40 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 274 282 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 SUPERFAMILY SSF55973 248 397 1.73E-65 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 Gene3D G3DSA:3.30.300.10 14 285 2.3E-166 T 14-10-2018 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 8 396 6.3E-165 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 248 386 7.4E-66 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 PIRSF PIRSF000497 1 398 1.9E-162 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 SUPERFAMILY SSF55973 123 247 8.63E-45 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 246 1.6E-42 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 Gene3D G3DSA:3.30.300.10 8 248 2.3E-166 T 14-10-2018 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_04765 6097ca9d36be34f652a461772c134ede 400 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 5 398 55.061 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 Gene3D G3DSA:3.40.50.2300 54 301 2.3E-74 T 14-10-2018 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 14-10-2018 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 SMART SM00354 1 70 3.0E-22 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 2 12 4.7E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 4.7E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 45 9.5E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 Pfam PF13377 Periplasmic binding protein-like domain 165 326 3.7E-45 T 14-10-2018 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 SUPERFAMILY SSF47413 1 59 1.08E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 Gene3D G3DSA:3.40.50.2300 157 286 2.3E-74 T 14-10-2018 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 Gene3D G3DSA:1.10.260.40 1 53 2.1E-20 T 14-10-2018 A4R43_06390 c74db4c1c07d552d31b7f486cba8c441 332 SUPERFAMILY SSF53822 60 327 1.41E-71 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_40270 3f5fb7f076c9f60e60d878ffd7ef343d 356 SUPERFAMILY SSF81345 18 349 1.83E-76 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_40270 3f5fb7f076c9f60e60d878ffd7ef343d 356 Pfam PF01032 FecCD transport family 28 348 2.4E-91 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_40270 3f5fb7f076c9f60e60d878ffd7ef343d 356 Gene3D G3DSA:1.10.3470.10 14 353 1.0E-97 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_26350 a63dbbc7c7e3c6c3c24b59750ed3b388 248 Gene3D G3DSA:3.20.20.70 1 248 1.1E-34 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_26350 a63dbbc7c7e3c6c3c24b59750ed3b388 248 Pfam PF01116 Fructose-bisphosphate aldolase class-II 15 246 6.2E-32 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_26350 a63dbbc7c7e3c6c3c24b59750ed3b388 248 SUPERFAMILY SSF51569 13 246 6.23E-36 T 14-10-2018 A4R43_26350 a63dbbc7c7e3c6c3c24b59750ed3b388 248 PIRSF PIRSF001359 13 248 2.1E-28 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_18550 b0eaad7c404fe2bf6e1fe57403690405 440 ProSitePatterns PS00482 Dihydroorotase signature 1. 58 66 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_18550 b0eaad7c404fe2bf6e1fe57403690405 440 SUPERFAMILY SSF51338 2 429 2.09E-19 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_18550 b0eaad7c404fe2bf6e1fe57403690405 440 Pfam PF01979 Amidohydrolase family 51 425 1.6E-29 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_18550 b0eaad7c404fe2bf6e1fe57403690405 440 TIGRFAM TIGR03178 allantoinase: allantoinase 2 432 1.9E-173 T 14-10-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 A4R43_18550 b0eaad7c404fe2bf6e1fe57403690405 440 Gene3D G3DSA:3.20.20.140 1 429 2.4E-135 T 14-10-2018 A4R43_18550 b0eaad7c404fe2bf6e1fe57403690405 440 SUPERFAMILY SSF51556 55 374 1.13E-96 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_32105 4c35d0dcb86a964530aff73329ef0cea 308 SUPERFAMILY SSF161098 36 295 5.23E-40 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_32105 4c35d0dcb86a964530aff73329ef0cea 308 Gene3D G3DSA:1.10.3720.10 76 307 1.4E-33 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_32105 4c35d0dcb86a964530aff73329ef0cea 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 307 2.1E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_32105 4c35d0dcb86a964530aff73329ef0cea 308 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 30 300 1.2E-81 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A4R43_24310 c163ec922ce377eb766489dc0d1321d3 813 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 652 721 6.1E-20 T 14-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain A4R43_24310 c163ec922ce377eb766489dc0d1321d3 813 SUPERFAMILY SSF48208 301 720 2.24E-49 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_24310 c163ec922ce377eb766489dc0d1321d3 813 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 208 296 5.1E-29 T 14-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain A4R43_24310 c163ec922ce377eb766489dc0d1321d3 813 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 30 197 2.3E-53 T 14-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal A4R43_24310 c163ec922ce377eb766489dc0d1321d3 813 Gene3D G3DSA:1.50.10.10 5 745 2.8E-273 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_24310 c163ec922ce377eb766489dc0d1321d3 813 PIRSF PIRSF010631 4 741 3.5E-215 T 14-10-2018 IPR016007 Alpha-L-rhamnosidase A4R43_24310 c163ec922ce377eb766489dc0d1321d3 813 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 305 650 3.2E-118 T 14-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain A4R43_17180 76e9b5962834142403a42c9a894b8c9e 407 SUPERFAMILY SSF103473 18 403 2.49E-35 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_17180 76e9b5962834142403a42c9a894b8c9e 407 Gene3D G3DSA:1.20.1250.20 225 407 6.3E-12 T 14-10-2018 A4R43_17180 76e9b5962834142403a42c9a894b8c9e 407 Gene3D G3DSA:1.20.1250.20 18 204 3.6E-10 T 14-10-2018 A4R43_17180 76e9b5962834142403a42c9a894b8c9e 407 Pfam PF07690 Major Facilitator Superfamily 27 283 3.2E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_12085 7cb684dae889b89297589862d43156b1 673 Gene3D G3DSA:1.10.510.10 203 351 1.9E-79 T 14-10-2018 A4R43_12085 7cb684dae889b89297589862d43156b1 673 SUPERFAMILY SSF48452 448 555 3.04E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12085 7cb684dae889b89297589862d43156b1 673 Pfam PF16919 Protein kinase G rubredoxin domain 51 120 2.1E-13 T 14-10-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A4R43_12085 7cb684dae889b89297589862d43156b1 673 Pfam PF16918 Protein kinase G tetratricopeptide repeat 415 671 5.6E-58 T 14-10-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A4R43_12085 7cb684dae889b89297589862d43156b1 673 SUPERFAMILY SSF56112 109 329 7.34E-39 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_12085 7cb684dae889b89297589862d43156b1 673 Gene3D G3DSA:1.25.40.10 416 513 1.6E-74 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12085 7cb684dae889b89297589862d43156b1 673 Gene3D G3DSA:1.25.40.10 514 669 1.6E-74 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12085 7cb684dae889b89297589862d43156b1 673 Pfam PF00069 Protein kinase domain 126 328 8.2E-26 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_12085 7cb684dae889b89297589862d43156b1 673 Gene3D G3DSA:3.30.200.20 74 202 1.9E-79 T 14-10-2018 A4R43_06775 8085c97f0774415c954d3098d6710024 641 SUPERFAMILY SSF161098 63 255 1.11E-19 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06775 8085c97f0774415c954d3098d6710024 641 Gene3D G3DSA:3.40.50.300 319 636 1.8E-92 T 14-10-2018 A4R43_06775 8085c97f0774415c954d3098d6710024 641 SUPERFAMILY SSF52540 320 560 7.39E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06775 8085c97f0774415c954d3098d6710024 641 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 257 9.8E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_06775 8085c97f0774415c954d3098d6710024 641 ProSitePatterns PS00211 ABC transporters family signature. 462 476 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_06775 8085c97f0774415c954d3098d6710024 641 Gene3D G3DSA:1.10.3720.10 59 263 1.5E-15 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06775 8085c97f0774415c954d3098d6710024 641 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 542 605 1.0E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_06775 8085c97f0774415c954d3098d6710024 641 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 539 625 5.3E-22 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_06775 8085c97f0774415c954d3098d6710024 641 Pfam PF00005 ABC transporter 342 489 6.8E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_06775 8085c97f0774415c954d3098d6710024 641 SMART SM00382 349 539 4.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_35545 3ae0bf63640fe1dd09785db9cd9ea4d1 353 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 6 351 5.0E-154 T 14-10-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 A4R43_35545 3ae0bf63640fe1dd09785db9cd9ea4d1 353 Gene3D G3DSA:3.40.630.10 16 341 4.1E-97 T 14-10-2018 A4R43_35545 3ae0bf63640fe1dd09785db9cd9ea4d1 353 SUPERFAMILY SSF53187 8 351 3.52E-43 T 14-10-2018 A4R43_35545 3ae0bf63640fe1dd09785db9cd9ea4d1 353 Pfam PF07687 Peptidase dimerisation domain 167 264 4.5E-12 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_35545 3ae0bf63640fe1dd09785db9cd9ea4d1 353 SUPERFAMILY SSF55031 167 268 1.02E-17 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_35545 3ae0bf63640fe1dd09785db9cd9ea4d1 353 Gene3D G3DSA:3.30.70.360 167 275 4.1E-97 T 14-10-2018 A4R43_35545 3ae0bf63640fe1dd09785db9cd9ea4d1 353 Pfam PF01546 Peptidase family M20/M25/M40 66 351 4.8E-22 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_12620 66817c797e114922b573744099269dcf 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_12620 66817c797e114922b573744099269dcf 234 SUPERFAMILY SSF51735 2 232 2.0E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 231 1.2E-57 T 14-10-2018 A4R43_12620 66817c797e114922b573744099269dcf 234 Gene3D G3DSA:3.40.50.720 1 233 2.0E-78 T 14-10-2018 A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 1.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12620 66817c797e114922b573744099269dcf 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 175 2.0E-6 T 14-10-2018 A4R43_22250 726239ed156f4e1a4209de695b9524ea 210 Gene3D G3DSA:1.25.40.340 3 210 6.3E-61 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_22250 726239ed156f4e1a4209de695b9524ea 210 SMART SM01120 32 207 4.2E-72 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_22250 726239ed156f4e1a4209de695b9524ea 210 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 11 206 1.7E-69 T 14-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 A4R43_22250 726239ed156f4e1a4209de695b9524ea 210 Pfam PF02734 DAK2 domain 32 206 5.7E-55 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_22250 726239ed156f4e1a4209de695b9524ea 210 SUPERFAMILY SSF101473 5 208 1.27E-52 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_35495 f292f547513c72fd560666210acba812 446 Gene3D G3DSA:3.40.109.10 241 444 4.8E-50 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_35495 f292f547513c72fd560666210acba812 446 Gene3D G3DSA:3.90.1660.10 57 239 9.8E-70 T 14-10-2018 A4R43_35495 f292f547513c72fd560666210acba812 446 Pfam PF00881 Nitroreductase family 257 425 1.8E-24 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4R43_35495 f292f547513c72fd560666210acba812 446 SUPERFAMILY SSF55469 252 441 1.44E-35 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_35495 f292f547513c72fd560666210acba812 446 Gene3D G3DSA:3.30.1330.100 13 225 9.8E-70 T 14-10-2018 A4R43_35495 f292f547513c72fd560666210acba812 446 Pfam PF01996 F420-0:Gamma-glutamyl ligase 17 216 2.5E-42 T 14-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4R43_35495 f292f547513c72fd560666210acba812 446 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 14 446 51.102 T 14-10-2018 IPR023661 Coenzyme F420:L-glutamate ligase, Actinobacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4R43_35495 f292f547513c72fd560666210acba812 446 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 252 444 4.3E-89 T 14-10-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4R43_35495 f292f547513c72fd560666210acba812 446 SUPERFAMILY SSF144010 10 244 3.01E-68 T 14-10-2018 A4R43_35495 f292f547513c72fd560666210acba812 446 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 9 239 1.7E-81 T 14-10-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4R43_16740 6656da446dc897932357b7f77287a4be 467 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.0E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_16740 6656da446dc897932357b7f77287a4be 467 SUPERFAMILY SSF46785 7 80 7.27E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_16740 6656da446dc897932357b7f77287a4be 467 Pfam PF00155 Aminotransferase class I and II 142 426 7.2E-22 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_16740 6656da446dc897932357b7f77287a4be 467 SUPERFAMILY SSF53383 113 466 1.36E-88 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_16740 6656da446dc897932357b7f77287a4be 467 Gene3D G3DSA:3.40.640.10 108 461 1.1E-114 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_16740 6656da446dc897932357b7f77287a4be 467 Gene3D G3DSA:1.10.10.10 11 79 1.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_16740 6656da446dc897932357b7f77287a4be 467 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 4.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_16740 6656da446dc897932357b7f77287a4be 467 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 4.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_16740 6656da446dc897932357b7f77287a4be 467 SMART SM00345 17 76 2.9E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 885 166.054 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 Gene3D G3DSA:3.10.310.40 772 884 1.8E-26 T 14-10-2018 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 SUPERFAMILY SSF55186 560 721 9.29E-42 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 865 1.2E-255 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 Gene3D G3DSA:3.30.980.10 561 720 5.5E-37 T 14-10-2018 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 SUPERFAMILY SSF55681 2 248 1.22E-85 T 14-10-2018 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 Pfam PF01411 tRNA synthetases class II (A) 5 563 9.0E-194 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 Gene3D G3DSA:2.40.30.130 457 554 3.8E-12 T 14-10-2018 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 661 704 1.3E-13 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 SUPERFAMILY SSF101353 249 446 3.27E-58 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 5.5E-26 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 5.5E-26 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 5.5E-26 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 5.5E-26 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 5.5E-26 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 Gene3D G3DSA:3.30.930.10 1 245 3.2E-90 T 14-10-2018 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 Pfam PF02272 DHHA1 domain 742 882 7.6E-20 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 SMART SM00863 661 704 1.6E-16 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A4R43_04530 f0365ad02f43fa5e3b7d23caa4df49d5 885 SUPERFAMILY SSF50447 460 558 2.37E-18 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 Pfam PF06029 AlkA N-terminal domain 212 324 1.8E-32 T 14-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 SMART SM00478 334 493 2.2E-14 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 SUPERFAMILY SSF48150 315 491 6.11E-36 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 Gene3D G3DSA:1.10.340.30 326 441 1.7E-26 T 14-10-2018 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 149 191 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 SMART SM00342 112 195 2.1E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 Gene3D G3DSA:1.10.10.60 96 202 7.3E-17 T 14-10-2018 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 SMART SM01009 211 324 1.5E-51 T 14-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 Gene3D G3DSA:3.40.10.10 11 84 1.5E-28 T 14-10-2018 IPR035451 Ada-like domain superfamily A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 SUPERFAMILY SSF46689 149 197 2.51E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 Pfam PF02805 Metal binding domain of Ada 20 83 1.4E-28 T 14-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 SUPERFAMILY SSF55945 212 307 2.04E-27 T 14-10-2018 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 SUPERFAMILY SSF57884 13 97 6.02E-31 T 14-10-2018 IPR035451 Ada-like domain superfamily A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 Pfam PF12833 Helix-turn-helix domain 118 196 5.1E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 Gene3D G3DSA:3.30.310.20 211 324 2.4E-29 T 14-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily A4R43_23455 093c110f0b0153594b6ce7850b6e48af 495 Gene3D G3DSA:1.10.1670.10 444 494 3.7E-11 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 Gene3D G3DSA:3.30.70.120 1 112 5.1E-44 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 SMART SM00938 4 105 1.2E-57 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 PRINTS PR00340 P-II protein signature 23 41 8.8E-37 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 PRINTS PR00340 P-II protein signature 83 103 8.8E-37 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 PRINTS PR00340 P-II protein signature 2 17 8.8E-37 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 PRINTS PR00340 P-II protein signature 52 75 8.8E-37 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 PIRSF PIRSF039144 1 112 4.0E-52 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.4E-39 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A4R43_18505 6d6f5aaeb1d437193358f8f0d1a18665 112 SUPERFAMILY SSF54913 1 112 2.86E-42 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4R43_16840 f8a6d3e6477f8126afe975c97e1c3c7f 412 Gene3D G3DSA:1.20.1250.20 9 398 1.4E-41 T 14-10-2018 A4R43_16840 f8a6d3e6477f8126afe975c97e1c3c7f 412 SUPERFAMILY SSF103473 11 402 5.23E-48 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_16840 f8a6d3e6477f8126afe975c97e1c3c7f 412 Pfam PF05977 Transmembrane secretion effector 8 405 5.0E-31 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_30060 ede6752c712ef54b526756add7ae259b 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_30060 ede6752c712ef54b526756add7ae259b 499 Gene3D G3DSA:3.40.309.10 272 464 1.9E-192 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_30060 ede6752c712ef54b526756add7ae259b 499 Pfam PF00171 Aldehyde dehydrogenase family 36 494 1.6E-184 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_30060 ede6752c712ef54b526756add7ae259b 499 SUPERFAMILY SSF53720 23 497 1.03E-174 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_30060 ede6752c712ef54b526756add7ae259b 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_30060 ede6752c712ef54b526756add7ae259b 499 Gene3D G3DSA:3.40.605.10 28 492 1.9E-192 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_04070 48fe9d5b4c0fb462348a282f3be29d77 371 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 217 355 7.7E-18 T 14-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain A4R43_04070 48fe9d5b4c0fb462348a282f3be29d77 371 Pfam PF07005 Putative sugar-binding N-terminal domain 4 112 3.9E-11 T 14-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain A4R43_04070 48fe9d5b4c0fb462348a282f3be29d77 371 Gene3D G3DSA:3.40.50.10840 3 201 1.9E-17 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily A4R43_04070 48fe9d5b4c0fb462348a282f3be29d77 371 Gene3D G3DSA:3.40.980.20 207 364 1.9E-16 T 14-10-2018 A4R43_04070 48fe9d5b4c0fb462348a282f3be29d77 371 SUPERFAMILY SSF142764 4 362 9.94E-48 T 14-10-2018 A4R43_34000 1f30eeac77caf5e8167a5ac9dc8026ad 196 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 116 3.2E-38 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_34000 1f30eeac77caf5e8167a5ac9dc8026ad 196 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_34000 1f30eeac77caf5e8167a5ac9dc8026ad 196 Pfam PF01196 Ribosomal protein L17 20 116 4.1E-35 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_34000 1f30eeac77caf5e8167a5ac9dc8026ad 196 SUPERFAMILY SSF64263 1 117 1.44E-44 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_34000 1f30eeac77caf5e8167a5ac9dc8026ad 196 Gene3D G3DSA:3.90.1030.10 1 116 1.2E-42 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_34000 1f30eeac77caf5e8167a5ac9dc8026ad 196 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.112 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_13325 428f4290c318301202aa6c127da3e09d 328 Pfam PF13377 Periplasmic binding protein-like domain 169 328 5.9E-32 T 14-10-2018 A4R43_13325 428f4290c318301202aa6c127da3e09d 328 Gene3D G3DSA:3.40.50.2300 159 293 3.8E-70 T 14-10-2018 A4R43_13325 428f4290c318301202aa6c127da3e09d 328 Gene3D G3DSA:1.10.260.40 2 60 3.8E-21 T 14-10-2018 A4R43_13325 428f4290c318301202aa6c127da3e09d 328 SMART SM00354 2 72 1.6E-26 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_13325 428f4290c318301202aa6c127da3e09d 328 SUPERFAMILY SSF53822 63 327 1.29E-59 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_13325 428f4290c318301202aa6c127da3e09d 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 2.5E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_13325 428f4290c318301202aa6c127da3e09d 328 SUPERFAMILY SSF47413 3 60 1.91E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_13325 428f4290c318301202aa6c127da3e09d 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 14-10-2018 A4R43_13325 428f4290c318301202aa6c127da3e09d 328 Gene3D G3DSA:3.40.50.2300 61 306 3.8E-70 T 14-10-2018 A4R43_36305 916ff3584082b4a9e45f520e52b7d2aa 434 SUPERFAMILY SSF51690 143 431 3.66E-85 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4R43_36305 916ff3584082b4a9e45f520e52b7d2aa 434 Gene3D G3DSA:3.20.20.70 160 310 4.0E-48 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_36305 916ff3584082b4a9e45f520e52b7d2aa 434 SUPERFAMILY SSF54675 10 141 2.59E-41 T 14-10-2018 A4R43_36305 916ff3584082b4a9e45f520e52b7d2aa 434 Gene3D G3DSA:3.20.140.10 5 159 7.8E-44 T 14-10-2018 A4R43_36305 916ff3584082b4a9e45f520e52b7d2aa 434 PIRSF PIRSF000484 5 431 1.2E-98 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A4R43_36305 916ff3584082b4a9e45f520e52b7d2aa 434 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 13 424 6.0E-134 T 14-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 A4R43_36305 916ff3584082b4a9e45f520e52b7d2aa 434 Gene3D G3DSA:3.20.140.10 311 382 1.6E-5 T 14-10-2018 A4R43_36305 916ff3584082b4a9e45f520e52b7d2aa 434 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 143 312 5.8E-8 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 Gene3D G3DSA:3.30.300.180 5 85 4.0E-8 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 SUPERFAMILY SSF48295 447 552 2.54E-35 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 463 529 1.8E-28 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 SMART SM00382 248 376 4.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 12 550 2.1E-154 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 SMART SM00760 460 529 5.4E-34 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 SUPERFAMILY SSF52540 215 427 3.56E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 281 295 6.1E-52 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 313 327 6.1E-52 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 347 374 6.1E-52 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 510 529 6.1E-52 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 249 269 6.1E-52 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 Gene3D G3DSA:1.10.8.60 382 452 2.7E-25 T 14-10-2018 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 Gene3D G3DSA:1.10.1750.10 456 556 2.1E-36 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 ProSitePatterns PS01008 DnaA protein signature. 510 529 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 Gene3D G3DSA:3.40.50.300 203 380 3.9E-52 T 14-10-2018 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 551 32.891 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4R43_30435 ba005e0df77bb367b91ea18ba95f4f99 556 Pfam PF00308 Bacterial dnaA protein 216 433 1.2E-102 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SUPERFAMILY SSF46894 2 84 7.37E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SUPERFAMILY SSF52540 243 499 1.19E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 Pfam PF03704 Bacterial transcriptional activator domain 91 231 4.0E-27 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 Gene3D G3DSA:1.25.40.10 88 266 2.9E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM00028 883 916 38.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM00028 763 796 95.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM00028 843 876 15.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM00028 723 756 46.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM00028 803 836 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM00028 96 129 360.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM00028 683 716 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SUPERFAMILY SSF48452 782 951 6.2E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 Pfam PF00486 Transcriptional regulatory protein, C terminal 21 82 5.4E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SUPERFAMILY SSF48452 680 794 3.29E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 Gene3D G3DSA:1.25.40.10 638 951 2.5E-52 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM00862 11 84 3.7E-5 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 Pfam PF13424 Tetratricopeptide repeat 803 874 1.5E-11 T 14-10-2018 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 Pfam PF13424 Tetratricopeptide repeat 735 794 1.3E-7 T 14-10-2018 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SUPERFAMILY SSF48452 86 249 1.26E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 SMART SM01043 91 235 1.1E-28 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 Pfam PF00931 NB-ARC domain 267 503 1.0E-5 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_25085 248247142ba5acd5070a5fb8d0f6a595 979 Gene3D G3DSA:1.10.10.10 1 87 1.1E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03265 339f2b26a468d51fdc8d494635fd5f45 177 Gene3D G3DSA:1.10.10.10 88 173 6.5E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03265 339f2b26a468d51fdc8d494635fd5f45 177 Pfam PF04542 Sigma-70 region 2 30 90 1.1E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_03265 339f2b26a468d51fdc8d494635fd5f45 177 SUPERFAMILY SSF88946 8 101 8.24E-21 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_03265 339f2b26a468d51fdc8d494635fd5f45 177 Pfam PF08281 Sigma-70, region 4 116 166 2.2E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_03265 339f2b26a468d51fdc8d494635fd5f45 177 SUPERFAMILY SSF88659 106 170 1.72E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_03265 339f2b26a468d51fdc8d494635fd5f45 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 169 8.9E-21 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_03265 339f2b26a468d51fdc8d494635fd5f45 177 Gene3D G3DSA:1.10.1740.10 5 87 2.8E-17 T 14-10-2018 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 PRINTS PR01035 Tetracycline resistance protein signature 25 41 2.6E-11 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 PRINTS PR01035 Tetracycline resistance protein signature 254 274 2.6E-11 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 PRINTS PR01035 Tetracycline resistance protein signature 168 188 2.6E-11 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 PRINTS PR01035 Tetracycline resistance protein signature 343 366 2.6E-11 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 PRINTS PR01035 Tetracycline resistance protein signature 140 162 2.6E-11 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 Pfam PF00083 Sugar (and other) transporter 254 395 5.0E-9 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 Pfam PF07690 Major Facilitator Superfamily 21 246 2.6E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 SUPERFAMILY SSF103473 13 403 3.79E-71 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 Gene3D G3DSA:1.20.1720.10 247 412 2.7E-21 T 14-10-2018 A4R43_34670 f2bb784904904afed92fb939dac3a4b0 418 Gene3D G3DSA:1.20.1250.20 10 246 6.9E-43 T 14-10-2018 A4R43_05465 67d04b62df363f2170d09c403b2ee789 248 Gene3D G3DSA:3.40.1210.10 1 243 2.6E-54 T 14-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A4R43_05465 67d04b62df363f2170d09c403b2ee789 248 SUPERFAMILY SSF64167 3 235 9.68E-43 T 14-10-2018 A4R43_05465 67d04b62df363f2170d09c403b2ee789 248 Pfam PF01975 Survival protein SurE 4 179 2.0E-37 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 Hamap MF_00235 Adenylate kinase [adk]. 2 181 42.147 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 PRINTS PR00094 Adenylate kinase signature 147 161 4.0E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 PRINTS PR00094 Adenylate kinase signature 5 18 4.0E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 PRINTS PR00094 Adenylate kinase signature 82 98 4.0E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 PRINTS PR00094 Adenylate kinase signature 130 145 4.0E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 PRINTS PR00094 Adenylate kinase signature 33 47 4.0E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 Pfam PF00406 Adenylate kinase 6 157 1.1E-51 T 14-10-2018 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 Gene3D G3DSA:3.40.50.300 1 181 3.1E-63 T 14-10-2018 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 TIGRFAM TIGR01351 adk: adenylate kinase 3 128 3.4E-50 T 14-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A4R43_33955 f5849b152a0962e7185d02cae5fda77a 184 SUPERFAMILY SSF52540 3 180 4.33E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_36220 5d50cb1dda5439a7780b219b3194b8ee 607 Gene3D G3DSA:1.10.10.2840 478 607 3.4E-17 T 14-10-2018 A4R43_36220 5d50cb1dda5439a7780b219b3194b8ee 607 PRINTS PR00833 Pollen allergen Poa pI signature 462 476 9.7E-6 T 14-10-2018 A4R43_36220 5d50cb1dda5439a7780b219b3194b8ee 607 PRINTS PR00833 Pollen allergen Poa pI signature 382 399 9.7E-6 T 14-10-2018 A4R43_36220 5d50cb1dda5439a7780b219b3194b8ee 607 PRINTS PR00833 Pollen allergen Poa pI signature 441 459 9.7E-6 T 14-10-2018 A4R43_36220 5d50cb1dda5439a7780b219b3194b8ee 607 Pfam PF07905 Purine catabolism regulatory protein-like family 7 119 3.8E-32 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain A4R43_36220 5d50cb1dda5439a7780b219b3194b8ee 607 Pfam PF13556 PucR C-terminal helix-turn-helix domain 545 602 2.4E-19 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF56801 439 980 3.4E-150 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.30.559.30 1220 1453 1.9E-114 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF00501 AMP-binding enzyme 484 865 3.3E-98 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF00501 AMP-binding enzyme 1586 1858 1.1E-63 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF00501 AMP-binding enzyme 1483 1576 2.6E-18 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF47336 1956 2022 4.84E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF47336 961 1033 1.83E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:1.10.1200.10 954 1038 5.9E-31 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:1.10.1200.10 1948 2032 2.1E-20 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 ProSitePatterns PS00012 Phosphopantetheine attachment site. 992 1007 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.30.559.30 2206 2430 5.9E-95 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.30.559.10 33 389 1.6E-130 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.30.559.10 2040 2377 5.9E-95 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SMART SM00823 Phosphopantetheine attachment site 1960 2026 2.4E-5 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SMART SM00823 Phosphopantetheine attachment site 968 1037 1.9E-6 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF52777 2202 2430 1.28E-46 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF52777 34 196 5.0E-44 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.30.300.30 1853 1947 5.8E-25 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF13193 AMP-binding enzyme C-terminal domain 1867 1935 2.0E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF13193 AMP-binding enzyme C-terminal domain 873 941 1.1E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF52777 1219 1456 7.45E-46 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.40.50.12780 480 859 6.6E-135 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF52777 2040 2210 4.17E-43 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1500 1882 1.4E-115 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 497 889 1.9E-130 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF52777 203 443 8.56E-58 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1598 1609 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF56801 1449 1972 1.07E-132 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.40.50.12780 1474 1850 1.7E-116 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 ProSitePatterns PS00455 Putative AMP-binding domain signature. 612 623 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF00550 Phosphopantetheine attachment site 969 1033 1.2E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF00550 Phosphopantetheine attachment site 1964 2022 6.7E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.30.559.10 1053 1399 1.9E-114 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF00668 Condensation domain 1050 1467 6.1E-66 T 14-10-2018 IPR001242 Condensation domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF00668 Condensation domain 2038 2429 6.8E-65 T 14-10-2018 IPR001242 Condensation domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Pfam PF00668 Condensation domain 33 456 1.9E-91 T 14-10-2018 IPR001242 Condensation domain A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 SUPERFAMILY SSF52777 1053 1216 1.61E-44 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.30.559.30 200 445 1.6E-130 T 14-10-2018 A4R43_08135 39ba05f9e41744a61217f3c592120f13 2432 Gene3D G3DSA:3.30.300.30 860 953 3.5E-27 T 14-10-2018 A4R43_17060 a8e30bf8aec69c50681f7c9a0d957768 363 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4R43_17060 a8e30bf8aec69c50681f7c9a0d957768 363 Pfam PF00348 Polyprenyl synthetase 43 307 2.3E-46 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A4R43_17060 a8e30bf8aec69c50681f7c9a0d957768 363 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 237 249 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4R43_17060 a8e30bf8aec69c50681f7c9a0d957768 363 Gene3D G3DSA:1.10.600.10 4 363 9.9E-117 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_17060 a8e30bf8aec69c50681f7c9a0d957768 363 SUPERFAMILY SSF48576 17 362 3.42E-71 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_02455 152a3f2abaa1bbd97485d1388b9c34d0 377 Pfam PF01266 FAD dependent oxidoreductase 1 342 3.1E-35 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_02455 152a3f2abaa1bbd97485d1388b9c34d0 377 SUPERFAMILY SSF54373 208 303 1.29E-6 T 14-10-2018 A4R43_02455 152a3f2abaa1bbd97485d1388b9c34d0 377 SUPERFAMILY SSF51905 1 352 3.37E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02455 152a3f2abaa1bbd97485d1388b9c34d0 377 Gene3D G3DSA:3.50.50.60 1 345 1.0E-74 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02455 152a3f2abaa1bbd97485d1388b9c34d0 377 Gene3D G3DSA:3.30.9.10 58 304 1.0E-74 T 14-10-2018 A4R43_05200 275ae3119b5321728740ed19d3e7b648 318 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 81 97 - T 14-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 A4R43_05200 275ae3119b5321728740ed19d3e7b648 318 SUPERFAMILY SSF53474 60 312 4.65E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_05200 275ae3119b5321728740ed19d3e7b648 318 Pfam PF07859 alpha/beta hydrolase fold 81 290 1.3E-44 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_05200 275ae3119b5321728740ed19d3e7b648 318 Gene3D G3DSA:3.40.50.1820 56 312 2.0E-69 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_05200 275ae3119b5321728740ed19d3e7b648 318 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 149 161 - T 14-10-2018 IPR033140 Lipase, GDXG, putative serine active site A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 Gene3D G3DSA:3.30.1490.20 158 223 9.5E-28 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 Pfam PF07478 D-ala D-ala ligase C-terminus 149 353 6.0E-67 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 109 120 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 Gene3D G3DSA:3.30.470.20 224 361 8.1E-43 T 14-10-2018 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 Pfam PF01820 D-ala D-ala ligase N-terminus 7 131 2.0E-29 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 356 40.107 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 SUPERFAMILY SSF56059 142 356 3.18E-52 T 14-10-2018 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 355 1.4E-105 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 PIRSF PIRSF039102 3 361 2.4E-106 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 Gene3D G3DSA:3.40.50.20 1 130 4.6E-39 T 14-10-2018 A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 SUPERFAMILY SSF52440 5 141 1.34E-34 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_19535 831f73f37a3bc4527ea4b8943ff426e5 363 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 298 326 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 107 121 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 SUPERFAMILY SSF55174 4 59 7.85E-14 T 14-10-2018 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 74 232 1.4E-45 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 Gene3D G3DSA:3.10.290.10 3 64 5.5E-20 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 Gene3D G3DSA:3.30.70.1560 131 221 2.6E-53 T 14-10-2018 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 Pfam PF01479 S4 domain 8 54 9.7E-13 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 Gene3D G3DSA:3.30.70.580 72 229 2.6E-53 T 14-10-2018 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 Pfam PF00849 RNA pseudouridylate synthase 70 201 3.0E-20 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 SMART SM00363 8 68 1.9E-11 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_14160 651945ab9893fdc827fcad4851b381e1 245 SUPERFAMILY SSF55120 52 241 4.86E-46 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_34285 8325c23d8b156464b6274e177af3014c 521 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 48 146 7.7E-32 T 14-10-2018 IPR032093 Phospholipase D, N-terminal A4R43_34285 8325c23d8b156464b6274e177af3014c 521 SUPERFAMILY SSF56300 150 510 6.45E-30 T 14-10-2018 A4R43_34285 8325c23d8b156464b6274e177af3014c 521 Pfam PF09423 PhoD-like phosphatase 158 490 1.4E-110 T 14-10-2018 IPR018946 Alkaline phosphatase D-related A4R43_34285 8325c23d8b156464b6274e177af3014c 521 Gene3D G3DSA:2.60.40.380 40 149 3.2E-37 T 14-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 A4R43_34285 8325c23d8b156464b6274e177af3014c 521 Gene3D G3DSA:3.60.21.70 151 521 2.9E-134 T 14-10-2018 IPR038607 PhoD-like superfamily A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 PRINTS PR00315 GTP-binding elongation factor signature 492 505 2.4E-9 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 PRINTS PR00315 GTP-binding elongation factor signature 596 605 2.4E-9 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 PRINTS PR00315 GTP-binding elongation factor signature 544 554 2.4E-9 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 PRINTS PR00315 GTP-binding elongation factor signature 560 571 2.4E-9 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Gene3D G3DSA:3.40.50.300 485 664 7.4E-67 T 14-10-2018 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Gene3D G3DSA:1.10.10.2480 3 63 5.1E-15 T 14-10-2018 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 SUPERFAMILY SSF52156 772 900 3.79E-35 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Gene3D G3DSA:3.40.50.10050 787 894 6.6E-34 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 491 650 5.3E-33 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Gene3D G3DSA:2.40.30.10 665 783 4.8E-40 T 14-10-2018 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 SUPERFAMILY SSF50447 894 992 1.96E-27 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 992 16.834 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Gene3D G3DSA:2.40.30.10 895 993 4.6E-30 T 14-10-2018 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 3 52 6.0E-15 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Pfam PF11987 Translation-initiation factor 2 781 883 2.4E-32 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 SUPERFAMILY SSF50447 666 749 3.33E-23 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 SUPERFAMILY SSF52540 489 655 9.21E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 400 991 5.6E-228 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 ProSitePatterns PS01176 Initiation factor 2 signature. 945 967 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4R43_41060 8de91f6aa1dd907f3ad91e0e1adbd740 993 Pfam PF00009 Elongation factor Tu GTP binding domain 493 653 1.3E-33 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_05385 a29fe18962660c5b23af8f0d12d39488 66 Gene3D G3DSA:3.90.820.10 1 63 1.4E-22 T 14-10-2018 A4R43_05385 a29fe18962660c5b23af8f0d12d39488 66 SUPERFAMILY SSF160582 1 54 4.05E-19 T 14-10-2018 IPR038020 MbtH-like domain superfamily A4R43_05385 a29fe18962660c5b23af8f0d12d39488 66 Pfam PF03621 MbtH-like protein 1 52 8.2E-24 T 14-10-2018 IPR005153 MbtH-like domain A4R43_05385 a29fe18962660c5b23af8f0d12d39488 66 SMART SM00923 3 53 1.8E-21 T 14-10-2018 IPR005153 MbtH-like domain A4R43_19350 e0bec03abe85abd7b2fa058388f0a28a 194 Gene3D G3DSA:3.90.550.10 2 190 5.4E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_19350 e0bec03abe85abd7b2fa058388f0a28a 194 Pfam PF12804 MobA-like NTP transferase domain 6 164 2.1E-32 T 14-10-2018 IPR025877 MobA-like NTP transferase A4R43_19350 e0bec03abe85abd7b2fa058388f0a28a 194 SUPERFAMILY SSF53448 4 187 1.71E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_41495 a88eb536ba7f804369cd3c5372516865 294 Gene3D G3DSA:3.40.50.300 1 232 5.3E-59 T 14-10-2018 A4R43_41495 a88eb536ba7f804369cd3c5372516865 294 SMART SM00382 18 213 2.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_41495 a88eb536ba7f804369cd3c5372516865 294 Pfam PF00005 ABC transporter 9 156 2.0E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_41495 a88eb536ba7f804369cd3c5372516865 294 SUPERFAMILY SSF52540 2 219 6.76E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41495 a88eb536ba7f804369cd3c5372516865 294 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_32840 df2196294f3415b48a362b54e8712de0 355 Pfam PF01553 Acyltransferase 127 257 1.1E-14 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_32840 df2196294f3415b48a362b54e8712de0 355 PIRSF PIRSF016753 45 355 1.3E-93 T 14-10-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted A4R43_32840 df2196294f3415b48a362b54e8712de0 355 SUPERFAMILY SSF69593 92 343 4.58E-30 T 14-10-2018 A4R43_32840 df2196294f3415b48a362b54e8712de0 355 SMART SM00563 141 260 1.7E-12 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_40955 1f594c1daf3612f9de2991f2abc9d6f6 561 Gene3D G3DSA:1.25.40.10 124 203 2.2E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_40955 1f594c1daf3612f9de2991f2abc9d6f6 561 SUPERFAMILY SSF48452 225 336 8.76E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_40955 1f594c1daf3612f9de2991f2abc9d6f6 561 Gene3D G3DSA:1.10.10.10 392 488 2.6E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40955 1f594c1daf3612f9de2991f2abc9d6f6 561 Gene3D G3DSA:1.25.40.10 204 348 2.0E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_40955 1f594c1daf3612f9de2991f2abc9d6f6 561 Gene3D G3DSA:1.25.40.10 494 561 1.9E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 SMART SM00304 176 229 1.2E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 Gene3D G3DSA:1.10.287.130 180 297 4.0E-27 T 14-10-2018 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 SMART SM00388 230 296 1.6E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 405 6.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 6.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 6.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 6.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 295 5.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 448 3.5E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 Pfam PF00672 HAMP domain 178 226 7.7E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 Gene3D G3DSA:3.30.565.10 302 449 1.5E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 SUPERFAMILY SSF47384 213 294 5.69E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 SUPERFAMILY SSF55874 286 450 3.14E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 SUPERFAMILY SSF158472 179 226 3.92E-5 T 14-10-2018 A4R43_24635 852e7e9833af966c083a3abeb37cdb40 465 SMART SM00387 340 450 1.6E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_14325 633377de82c37885413eb0eb32c55af0 383 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 1 383 1.4E-106 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_14325 633377de82c37885413eb0eb32c55af0 383 Gene3D G3DSA:3.10.20.340 258 383 3.6E-40 T 14-10-2018 A4R43_14325 633377de82c37885413eb0eb32c55af0 383 Gene3D G3DSA:3.60.70.12 1 178 3.4E-63 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_14325 633377de82c37885413eb0eb32c55af0 383 SUPERFAMILY SSF56266 6 379 6.15E-129 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_14325 633377de82c37885413eb0eb32c55af0 383 Gene3D G3DSA:3.30.2330.10 179 257 3.6E-24 T 14-10-2018 A4R43_14325 633377de82c37885413eb0eb32c55af0 383 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 381 4.0E-131 T 14-10-2018 A4R43_14325 633377de82c37885413eb0eb32c55af0 383 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 383 133.34 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_14325 633377de82c37885413eb0eb32c55af0 383 Pfam PF01960 ArgJ family 11 383 1.0E-128 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_08865 aa5a5f7a6963644071c678bc37246060 271 SUPERFAMILY SSF48498 106 258 4.0E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_08865 aa5a5f7a6963644071c678bc37246060 271 Gene3D G3DSA:1.10.10.60 13 91 3.5E-24 T 14-10-2018 A4R43_08865 aa5a5f7a6963644071c678bc37246060 271 SUPERFAMILY SSF46689 30 94 1.85E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08865 aa5a5f7a6963644071c678bc37246060 271 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 85 4.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08865 aa5a5f7a6963644071c678bc37246060 271 Gene3D G3DSA:1.10.357.10 93 257 1.4E-32 T 14-10-2018 A4R43_08865 aa5a5f7a6963644071c678bc37246060 271 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 105 254 5.4E-17 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 SUPERFAMILY SSF53067 4 154 4.1E-19 T 14-10-2018 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 SUPERFAMILY SSF53067 176 369 1.91E-35 T 14-10-2018 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 Gene3D G3DSA:3.30.420.40 5 367 2.8E-88 T 14-10-2018 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 Gene3D G3DSA:3.90.640.10 220 307 2.8E-88 T 14-10-2018 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 Pfam PF00012 Hsp70 protein 162 367 1.5E-27 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.6E-10 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 PRINTS PR00301 70kDa heat shock protein signature 356 376 1.6E-10 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 PRINTS PR00301 70kDa heat shock protein signature 187 197 1.6E-10 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.6E-10 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 PRINTS PR00301 70kDa heat shock protein signature 326 342 1.6E-10 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 181 194 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 329 343 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 Gene3D G3DSA:3.30.420.40 166 357 2.8E-88 T 14-10-2018 A4R43_34055 cc0cf0ac9c1b176d8a9bbe71e0f147fa 644 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 491 637 1.3E-17 T 14-10-2018 IPR023840 Type VII secretion system Rv3446c A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 38 226 7.1E-26 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 SUPERFAMILY SSF52518 250 516 8.03E-62 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 279 493 3.0E-53 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 30 626 4.7E-200 T 14-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 SUPERFAMILY SSF53323 32 241 1.02E-17 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 Gene3D G3DSA:3.40.50.920 531 634 9.9E-16 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 Gene3D G3DSA:3.40.50.970 240 441 6.4E-64 T 14-10-2018 A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 Gene3D G3DSA:3.40.920.10 28 239 1.5E-16 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A4R43_33240 ec4fbbd60caa94401f2833cebf787fce 639 SUPERFAMILY SSF52922 534 635 1.38E-9 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 SUPERFAMILY SSF46785 1 75 8.52E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 3.5E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 SMART SM00866 98 239 6.3E-4 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 Gene3D G3DSA:1.10.10.10 7 93 1.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 Pfam PF07702 UTRA domain 102 236 4.1E-13 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 SUPERFAMILY SSF64288 61 242 5.18E-20 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 8.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 8.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 SMART SM00345 14 73 9.8E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_27785 c9065b0e13dff06c913238c1bddc3e51 255 Gene3D G3DSA:3.40.1410.10 100 243 3.0E-19 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 283 311 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 SUPERFAMILY SSF56059 132 337 6.4E-54 T 14-10-2018 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 99 110 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 Gene3D G3DSA:3.40.50.20 1 121 2.0E-39 T 14-10-2018 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 SUPERFAMILY SSF52440 3 131 2.21E-36 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 Gene3D G3DSA:3.30.1490.20 147 210 2.4E-72 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 341 35.606 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 340 2.2E-84 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 Gene3D G3DSA:3.30.470.20 127 337 2.4E-72 T 14-10-2018 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 Pfam PF01820 D-ala D-ala ligase N-terminus 6 122 9.6E-26 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 PIRSF PIRSF039102 1 345 3.7E-107 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_21435 932175f1d2e5edd41d8a0acf3991fe65 345 Pfam PF07478 D-ala D-ala ligase C-terminus 141 337 1.1E-58 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_21295 1dffca51c9d1a27e81268fa5a0660820 605 Pfam PF00890 FAD binding domain 52 585 1.4E-99 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_21295 1dffca51c9d1a27e81268fa5a0660820 605 Gene3D G3DSA:3.90.700.10 331 428 3.5E-38 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_21295 1dffca51c9d1a27e81268fa5a0660820 605 Gene3D G3DSA:3.50.50.60 537 599 1.3E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21295 1dffca51c9d1a27e81268fa5a0660820 605 Gene3D G3DSA:3.50.50.60 53 330 3.5E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21295 1dffca51c9d1a27e81268fa5a0660820 605 Gene3D G3DSA:3.90.700.10 519 536 1.3E-16 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_21295 1dffca51c9d1a27e81268fa5a0660820 605 SUPERFAMILY SSF51905 44 601 3.69E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_03125 bf126740b67ea120f0e233fc83fe6431 152 Pfam PF12802 MarR family 32 88 1.2E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_03125 bf126740b67ea120f0e233fc83fe6431 152 SUPERFAMILY SSF46785 27 138 1.73E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03125 bf126740b67ea120f0e233fc83fe6431 152 SMART SM00347 25 125 1.4E-19 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_03125 bf126740b67ea120f0e233fc83fe6431 152 Gene3D G3DSA:1.10.10.10 2 139 5.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31795 def1e421ad36900c8ce3d12cbc4ac27a 242 PIRSF PIRSF039085 2 242 1.4E-100 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4R43_31795 def1e421ad36900c8ce3d12cbc4ac27a 242 SUPERFAMILY SSF52540 6 237 1.09E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31795 def1e421ad36900c8ce3d12cbc4ac27a 242 SMART SM00382 30 215 7.7E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_31795 def1e421ad36900c8ce3d12cbc4ac27a 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_31795 def1e421ad36900c8ce3d12cbc4ac27a 242 Gene3D G3DSA:3.40.50.300 4 242 9.4E-80 T 14-10-2018 A4R43_31795 def1e421ad36900c8ce3d12cbc4ac27a 242 Pfam PF00005 ABC transporter 21 167 6.3E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 Gene3D G3DSA:3.50.50.60 14 350 2.6E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 1.8E-35 T 14-10-2018 A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.8E-35 T 14-10-2018 A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 1.8E-35 T 14-10-2018 A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 1.8E-35 T 14-10-2018 A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 354 1.8E-35 T 14-10-2018 A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 338 1.8E-35 T 14-10-2018 A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 SUPERFAMILY SSF51905 12 379 3.94E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 Gene3D G3DSA:3.30.70.2450 193 276 2.6E-82 T 14-10-2018 A4R43_38490 b5bb10a407ff9a1077b0ad3741ce1d94 540 Pfam PF01494 FAD binding domain 12 350 7.4E-59 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_35240 707a16e7f1f5e252f149767570f6e15a 510 Pfam PF14021 Tuberculosis necrotizing toxin 429 481 1.8E-13 T 14-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 A4R43_38605 cd9082390feefa7106e7974c90791128 329 SMART SM00382 32 215 1.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_38605 cd9082390feefa7106e7974c90791128 329 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 15 312 2.7E-102 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_38605 cd9082390feefa7106e7974c90791128 329 Gene3D G3DSA:3.40.50.300 1 238 3.8E-65 T 14-10-2018 A4R43_38605 cd9082390feefa7106e7974c90791128 329 Pfam PF00005 ABC transporter 24 166 1.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_38605 cd9082390feefa7106e7974c90791128 329 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_38605 cd9082390feefa7106e7974c90791128 329 SUPERFAMILY SSF52540 6 229 2.45E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09200 8e41d250ba6e6e19876e85b83fafad5f 402 SUPERFAMILY SSF88946 8 74 1.65E-7 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_09200 8e41d250ba6e6e19876e85b83fafad5f 402 Gene3D G3DSA:1.10.10.10 106 158 4.7E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09200 8e41d250ba6e6e19876e85b83fafad5f 402 SUPERFAMILY SSF88659 97 156 1.48E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_09200 8e41d250ba6e6e19876e85b83fafad5f 402 SUPERFAMILY SSF48452 20 384 8.6E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_09200 8e41d250ba6e6e19876e85b83fafad5f 402 Pfam PF04542 Sigma-70 region 2 21 76 4.4E-5 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_09200 8e41d250ba6e6e19876e85b83fafad5f 402 Pfam PF08281 Sigma-70, region 4 106 154 2.6E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_39910 5579574bb644edfcbf18c446a91e6da9 486 Pfam PF08386 TAP-like protein 387 486 1.1E-25 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_39910 5579574bb644edfcbf18c446a91e6da9 486 SUPERFAMILY SSF53474 79 474 1.92E-25 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06615 b10807542a3f6442cf2dad169abb695c 487 Gene3D G3DSA:3.40.50.12780 3 380 1.6E-119 T 14-10-2018 A4R43_06615 b10807542a3f6442cf2dad169abb695c 487 Pfam PF13193 AMP-binding enzyme C-terminal domain 396 471 1.4E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_06615 b10807542a3f6442cf2dad169abb695c 487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_06615 b10807542a3f6442cf2dad169abb695c 487 Gene3D G3DSA:3.30.300.310 383 485 3.7E-35 T 14-10-2018 A4R43_06615 b10807542a3f6442cf2dad169abb695c 487 PRINTS PR00154 AMP-binding signature 142 153 6.8E-5 T 14-10-2018 IPR020459 AMP-binding A4R43_06615 b10807542a3f6442cf2dad169abb695c 487 PRINTS PR00154 AMP-binding signature 154 162 6.8E-5 T 14-10-2018 IPR020459 AMP-binding A4R43_06615 b10807542a3f6442cf2dad169abb695c 487 SUPERFAMILY SSF56801 11 483 8.5E-155 T 14-10-2018 A4R43_06615 b10807542a3f6442cf2dad169abb695c 487 Pfam PF00501 AMP-binding enzyme 12 387 2.2E-100 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 144 315 3.9E-44 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 427 509 1.5E-30 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 Pfam PF10531 SLBB domain 338 384 6.9E-6 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 SUPERFAMILY SSF140490 422 512 2.62E-31 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 SUPERFAMILY SSF142019 96 336 9.68E-86 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 SUPERFAMILY SSF52833 3 86 5.59E-6 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 Gene3D G3DSA:3.40.50.11540 149 327 1.8E-73 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 SMART SM00928 425 470 1.2E-19 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 Gene3D G3DSA:3.10.20.600 328 422 2.7E-27 T 14-10-2018 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 Gene3D G3DSA:1.20.1440.230 423 515 3.9E-26 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 SUPERFAMILY SSF142984 338 420 5.49E-22 T 14-10-2018 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 263 278 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05860 d5083a6009fc8d8bbfc63cbf43eaa9f3 515 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 438 449 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 Gene3D G3DSA:1.10.10.10 117 199 9.0E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 SUPERFAMILY SSF46767 119 197 2.62E-26 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 SUPERFAMILY SSF53155 37 114 2.94E-18 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 120 197 9.4E-30 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 168 174 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 120 198 4.8E-27 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 38 114 3.9E-8 T 14-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 Gene3D G3DSA:3.30.160.70 37 113 5.3E-21 T 14-10-2018 A4R43_20980 1653f42089a40caf91f6afa475d52d06 199 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 41 198 38.168 T 14-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A4R43_20240 2eb8d81ea62d3c2c2f94bb2fa3daf349 254 SUPERFAMILY SSF51161 37 223 2.73E-31 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_20240 2eb8d81ea62d3c2c2f94bb2fa3daf349 254 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 166 200 8.1E-8 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_20240 2eb8d81ea62d3c2c2f94bb2fa3daf349 254 Gene3D G3DSA:2.160.10.10 56 235 2.5E-33 T 14-10-2018 A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Gene3D G3DSA:3.40.366.10 562 862 1.1E-166 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Pfam PF00550 Phosphopantetheine attachment site 1210 1275 7.0E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 285 4.6E-87 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Pfam PF00698 Acyl transferase domain 563 877 6.2E-59 T 14-10-2018 IPR014043 Acyl transferase A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Gene3D G3DSA:1.10.1200.10 1191 1282 3.3E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 SUPERFAMILY SSF47336 1200 1282 1.57E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 526 4.9E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 SMART SM00823 Phosphopantetheine attachment site 1207 1279 1.8E-15 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 SUPERFAMILY SSF55048 691 752 1.29E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Pfam PF08990 Erythronolide synthase docking 6 28 2.0E-9 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 SUPERFAMILY SSF52151 560 846 1.2E-73 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 564 859 3.0E-123 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Gene3D G3DSA:3.30.70.3290 477 905 1.1E-166 T 14-10-2018 A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 SUPERFAMILY SSF53901 34 406 1.13E-100 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 409 5.5E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 Gene3D G3DSA:3.40.47.10 19 462 1.2E-181 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 SUPERFAMILY SSF51735 938 1059 2.28E-6 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37730 713cc696435bc3b401d04f223eaf8230 1285 SMART SM00825 Beta-ketoacyl synthase 39 462 4.0E-215 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_08355 5b2a98c479684cdc4390677de48f3f4a 463 Gene3D G3DSA:3.20.20.70 99 405 8.1E-75 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_08355 5b2a98c479684cdc4390677de48f3f4a 463 SUPERFAMILY SSF102114 156 417 2.31E-13 T 14-10-2018 A4R43_25555 9cd180d468391b3e5c3d2183bec5bab0 199 Gene3D G3DSA:3.90.1570.10 13 161 3.6E-19 T 14-10-2018 A4R43_25555 9cd180d468391b3e5c3d2183bec5bab0 199 Pfam PF05685 Putative restriction endonuclease 21 192 1.2E-20 T 14-10-2018 IPR008538 Domain of unknown function DUF820 A4R43_25555 9cd180d468391b3e5c3d2183bec5bab0 199 SUPERFAMILY SSF52980 15 158 3.75E-18 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4R43_07650 b14b323414e25678c3506bc5a28cb8a6 182 Gene3D G3DSA:3.30.450.150 56 182 2.4E-39 T 14-10-2018 IPR038084 GlcG-like domain superfamily A4R43_07650 b14b323414e25678c3506bc5a28cb8a6 182 SUPERFAMILY SSF143744 47 181 1.18E-32 T 14-10-2018 IPR038084 GlcG-like domain superfamily A4R43_07650 b14b323414e25678c3506bc5a28cb8a6 182 Pfam PF03928 Haem-degrading 55 178 2.8E-28 T 14-10-2018 IPR005624 Haem-degrading A4R43_15465 717155d01e6d47fd7b598eedbaa06382 539 Gene3D G3DSA:3.90.920.30 265 539 7.8E-88 T 14-10-2018 A4R43_15465 717155d01e6d47fd7b598eedbaa06382 539 Pfam PF13298 DNA polymerase Ligase (LigD) 48 154 9.1E-37 T 14-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain A4R43_15465 717155d01e6d47fd7b598eedbaa06382 539 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 252 501 8.8E-65 T 14-10-2018 IPR014145 DNA ligase D, polymerase domain A4R43_15465 717155d01e6d47fd7b598eedbaa06382 539 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 17 174 9.9E-65 T 14-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 Gene3D G3DSA:1.10.275.10 7 134 1.1E-51 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 SUPERFAMILY SSF48557 6 460 1.62E-141 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 Pfam PF00206 Lyase 14 338 1.9E-98 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 Gene3D G3DSA:1.20.200.10 135 403 5.7E-106 T 14-10-2018 A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 PRINTS PR00145 Argininosuccinate lyase family signature 313 329 2.3E-6 T 14-10-2018 A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 PRINTS PR00145 Argininosuccinate lyase family signature 171 191 2.3E-6 T 14-10-2018 A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 PRINTS PR00145 Argininosuccinate lyase family signature 129 151 2.3E-6 T 14-10-2018 A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 1.4E-32 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 PRINTS PR00149 Fumarate lyase superfamily signature 130 148 1.4E-32 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 PRINTS PR00149 Fumarate lyase superfamily signature 267 294 1.4E-32 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 PRINTS PR00149 Fumarate lyase superfamily signature 313 329 1.4E-32 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 ProSitePatterns PS00163 Fumarate lyases signature. 313 322 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 Gene3D G3DSA:1.10.40.30 404 460 1.6E-26 T 14-10-2018 A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 Hamap MF_00743 Fumarate hydratase class II [fumC]. 6 463 79.513 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_23525 0d00e812adc062def9fd89cb48c3bdc2 465 Pfam PF10415 Fumarase C C-terminus 404 461 6.9E-22 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_30050 779a6974f81c27928947fa163f94ee3e 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_30050 779a6974f81c27928947fa163f94ee3e 543 Pfam PF00501 AMP-binding enzyme 17 437 2.7E-96 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_30050 779a6974f81c27928947fa163f94ee3e 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 4.0E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_30050 779a6974f81c27928947fa163f94ee3e 543 Gene3D G3DSA:3.40.50.12780 1 432 5.6E-122 T 14-10-2018 A4R43_30050 779a6974f81c27928947fa163f94ee3e 543 SUPERFAMILY SSF56801 7 533 1.83E-143 T 14-10-2018 A4R43_30050 779a6974f81c27928947fa163f94ee3e 543 Gene3D G3DSA:3.30.300.310 433 534 8.3E-34 T 14-10-2018 A4R43_26390 f06d23339092af4c69a682d650d3b134 316 Pfam PF05138 Phenylacetic acid catabolic protein 26 300 2.8E-102 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 A4R43_26390 f06d23339092af4c69a682d650d3b134 316 SUPERFAMILY SSF47240 36 278 3.08E-82 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_26390 f06d23339092af4c69a682d650d3b134 316 Gene3D G3DSA:1.20.1260.10 9 316 1.2E-132 T 14-10-2018 IPR012347 Ferritin-like A4R43_26390 f06d23339092af4c69a682d650d3b134 316 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 16 304 6.1E-157 T 14-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 A4R43_28000 d3e43e64d2e079ecbb92b19076d72dc9 232 Pfam PF00027 Cyclic nucleotide-binding domain 39 124 5.6E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_28000 d3e43e64d2e079ecbb92b19076d72dc9 232 SUPERFAMILY SSF51206 19 142 9.03E-23 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like A4R43_28000 d3e43e64d2e079ecbb92b19076d72dc9 232 SMART SM00100 19 137 3.8E-8 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_28000 d3e43e64d2e079ecbb92b19076d72dc9 232 Gene3D G3DSA:2.60.120.10 16 152 9.9E-27 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_28000 d3e43e64d2e079ecbb92b19076d72dc9 232 Gene3D G3DSA:1.10.10.10 153 231 3.2E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28000 d3e43e64d2e079ecbb92b19076d72dc9 232 SMART SM00419 172 220 1.8E-4 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4R43_28000 d3e43e64d2e079ecbb92b19076d72dc9 232 SUPERFAMILY SSF46785 155 219 2.52E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_28000 d3e43e64d2e079ecbb92b19076d72dc9 232 Pfam PF13545 Crp-like helix-turn-helix domain 157 226 2.6E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 Pfam PF12840 Helix-turn-helix domain 18 76 1.8E-9 T 14-10-2018 A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 SUPERFAMILY SSF46785 12 141 3.18E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 SUPERFAMILY SSF52821 110 219 1.83E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 Pfam PF00581 Rhodanese-like domain 125 213 4.9E-15 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 ProSitePatterns PS00380 Rhodanese signature 1. 147 158 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 5.5E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 5.5E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 5.5E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 SMART SM00450 122 218 2.6E-23 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 SMART SM00418 19 97 2.7E-21 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 Gene3D G3DSA:1.10.10.10 4 105 1.6E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01595 d191c828b1dc0e873301bb59b545eeb8 226 Gene3D G3DSA:3.40.250.10 112 222 5.4E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_09150 49567356a6335601386e47eb64fc79cf 166 Gene3D G3DSA:3.30.530.20 10 166 1.1E-43 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_09150 49567356a6335601386e47eb64fc79cf 166 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 13 139 8.6E-17 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_09150 49567356a6335601386e47eb64fc79cf 166 SUPERFAMILY SSF55961 12 166 1.22E-24 T 14-10-2018 A4R43_20185 f8b14f42d7320b120161661abf5a8870 337 Gene3D G3DSA:3.30.450.40 4 146 7.3E-31 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_20185 f8b14f42d7320b120161661abf5a8870 337 Pfam PF13185 GAF domain 2 129 3.2E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_20185 f8b14f42d7320b120161661abf5a8870 337 SUPERFAMILY SSF55874 221 336 1.58E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_20185 f8b14f42d7320b120161661abf5a8870 337 SMART SM00065 2 139 1.7E-11 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_20185 f8b14f42d7320b120161661abf5a8870 337 Gene3D G3DSA:3.30.565.10 214 336 8.3E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_20185 f8b14f42d7320b120161661abf5a8870 337 SUPERFAMILY SSF55781 5 143 3.93E-19 T 14-10-2018 A4R43_20185 f8b14f42d7320b120161661abf5a8870 337 Pfam PF07730 Histidine kinase 146 207 5.8E-12 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_07425 f311a65b86b3e9bffca24600927957e8 801 SUPERFAMILY SSF102588 30 246 6.54E-33 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_07425 f311a65b86b3e9bffca24600927957e8 801 Pfam PF02585 GlcNAc-PI de-N-acetylase 33 166 3.6E-20 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4R43_07425 f311a65b86b3e9bffca24600927957e8 801 SUPERFAMILY SSF49344 495 693 7.45E-26 T 14-10-2018 A4R43_07425 f311a65b86b3e9bffca24600927957e8 801 Gene3D G3DSA:3.40.50.10320 22 207 1.0E-37 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_07425 f311a65b86b3e9bffca24600927957e8 801 Pfam PF06452 Carbohydrate family 9 binding domain-like 504 694 4.8E-32 T 14-10-2018 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_07425 f311a65b86b3e9bffca24600927957e8 801 ProDom PD004647 DEGRADATION HYDROLASE GLYCOSIDASE XYLAN A XYLANASE PRECURSOR SIGNAL REPEAT 14- 540 692 0.005 T 14-10-2018 A4R43_07425 f311a65b86b3e9bffca24600927957e8 801 Gene3D G3DSA:2.60.40.1190 495 694 4.1E-29 T 14-10-2018 A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 SUPERFAMILY SSF52172 2 176 4.39E-19 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 Pfam PF00072 Response regulator receiver domain 2 105 1.9E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 SMART SM00448 1 118 2.9E-4 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 191 7.3E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 3.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 3.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 3.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 SMART SM00421 144 206 3.9E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39280 9a92c1d1d2ad329c50dfbd240912c730 210 Gene3D G3DSA:3.40.50.12740 1 207 3.6E-44 T 14-10-2018 A4R43_16890 760ae7ec174e38d1adf14cc76f2fefe3 305 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 5 302 1.9E-67 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A4R43_16890 760ae7ec174e38d1adf14cc76f2fefe3 305 Gene3D G3DSA:3.40.190.10 104 241 5.0E-72 T 14-10-2018 A4R43_16890 760ae7ec174e38d1adf14cc76f2fefe3 305 Pfam PF16868 NMT1-like family 29 301 8.4E-51 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A4R43_16890 760ae7ec174e38d1adf14cc76f2fefe3 305 Gene3D G3DSA:3.40.190.10 29 301 5.0E-72 T 14-10-2018 A4R43_16890 760ae7ec174e38d1adf14cc76f2fefe3 305 SUPERFAMILY SSF53850 25 301 1.5E-60 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Pfam PF00501 AMP-binding enzyme 529 925 9.4E-89 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 SUPERFAMILY SSF56801 486 1049 2.75E-153 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 SMART SM00823 Phosphopantetheine attachment site 1037 1106 9.2E-5 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Pfam PF00668 Condensation domain 64 506 1.5E-91 T 14-10-2018 IPR001242 Condensation domain A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 ProSitePatterns PS00455 Putative AMP-binding domain signature. 666 677 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Gene3D G3DSA:3.40.50.1820 1027 1108 2.7E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Gene3D G3DSA:3.30.300.30 919 1026 2.7E-35 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 SUPERFAMILY SSF52777 60 263 1.45E-41 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 SUPERFAMILY SSF47336 1030 1102 3.53E-20 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Pfam PF00550 Phosphopantetheine attachment site 1038 1101 5.1E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Gene3D G3DSA:3.30.559.30 247 493 1.3E-128 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1061 1076 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Gene3D G3DSA:3.30.559.10 66 436 1.3E-128 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Pfam PF13193 AMP-binding enzyme C-terminal domain 933 1008 5.1E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 PIRSF PIRSF001617 972 1107 7.2E-17 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 PIRSF PIRSF001617 889 977 5.6E-19 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 PIRSF PIRSF001617 251 634 7.3E-22 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 PIRSF PIRSF001617 655 894 0.0018 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Gene3D G3DSA:3.40.50.12780 518 917 4.5E-131 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 SUPERFAMILY SSF52777 251 514 9.78E-60 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 Gene3D G3DSA:1.10.10.1830 3 55 4.2E-12 T 14-10-2018 A4R43_02320 947a17a30d372ec913d912cf6a3f8298 1108 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 549 949 6.1E-123 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 SUPERFAMILY SSF88946 8 91 5.89E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 SUPERFAMILY SSF54427 180 304 2.0E-15 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 Gene3D G3DSA:3.10.450.50 171 305 6.6E-10 T 14-10-2018 A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 Gene3D G3DSA:1.10.10.10 115 170 9.1E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 SUPERFAMILY SSF88659 115 171 4.86E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 Pfam PF12680 SnoaL-like domain 188 293 3.5E-7 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 171 5.5E-16 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 Gene3D G3DSA:1.10.1740.10 5 82 6.9E-8 T 14-10-2018 A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 Pfam PF04542 Sigma-70 region 2 13 78 1.8E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_39835 1e985793d3e48510dfa0586dcc8b3d7a 308 Pfam PF08281 Sigma-70, region 4 118 169 3.1E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 SMART SM01012 30 85 2.4E-9 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 594 775 3.1E-44 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 Gene3D G3DSA:3.30.450.20 406 470 7.4E-7 T 14-10-2018 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 SUPERFAMILY SSF81606 585 771 3.66E-8 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 Gene3D G3DSA:3.30.450.40 115 264 1.4E-8 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 Gene3D G3DSA:3.30.450.20 275 405 4.0E-6 T 14-10-2018 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 Gene3D G3DSA:2.10.70.100 474 520 2.6E-5 T 14-10-2018 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 Gene3D G3DSA:3.60.40.10 529 775 6.3E-55 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 SUPERFAMILY SSF55781 130 263 4.71E-7 T 14-10-2018 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 SMART SM00331 567 775 9.7E-28 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 SUPERFAMILY SSF52172 20 85 1.44E-5 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 Pfam PF03861 ANTAR domain 33 85 8.5E-10 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_05730 e8230370a1d22019cdfe476bd2d073fe 776 SUPERFAMILY SSF55785 426 519 1.17E-8 T 14-10-2018 IPR035965 PAS domain superfamily A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 Gene3D G3DSA:2.60.260.20 118 254 1.9E-31 T 14-10-2018 A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 SMART SM00271 3 60 1.8E-27 T 14-10-2018 IPR001623 DnaJ domain A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 384 36.339 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 SUPERFAMILY SSF49493 264 354 2.22E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 Pfam PF00684 DnaJ central domain 148 212 6.3E-12 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 Pfam PF01556 DnaJ C terminal domain 124 343 1.7E-37 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 Gene3D G3DSA:1.10.287.110 1 111 3.0E-30 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 SUPERFAMILY SSF49493 120 262 9.68E-17 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 Gene3D G3DSA:2.60.260.20 259 371 4.0E-29 T 14-10-2018 A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 PRINTS PR00625 DnaJ domain signature 6 24 2.2E-21 T 14-10-2018 IPR001623 DnaJ domain A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 PRINTS PR00625 DnaJ domain signature 24 39 2.2E-21 T 14-10-2018 IPR001623 DnaJ domain A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 PRINTS PR00625 DnaJ domain signature 40 60 2.2E-21 T 14-10-2018 IPR001623 DnaJ domain A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 PRINTS PR00625 DnaJ domain signature 60 79 2.2E-21 T 14-10-2018 IPR001623 DnaJ domain A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 Pfam PF00226 DnaJ domain 4 65 7.4E-24 T 14-10-2018 IPR001623 DnaJ domain A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 SUPERFAMILY SSF57938 135 215 1.44E-17 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 SUPERFAMILY SSF46565 3 103 2.62E-30 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_39640 5297258e85dac05750e9ba12ded6126f 386 Gene3D G3DSA:2.10.230.10 148 212 1.9E-31 T 14-10-2018 A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 Gene3D G3DSA:1.20.120.530 87 225 9.3E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 1.7E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 1.7E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 SUPERFAMILY SSF46785 3 68 1.11E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 64 2.1E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 SMART SM00345 5 64 6.7E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 SUPERFAMILY SSF48008 88 222 2.88E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 Gene3D G3DSA:1.10.10.10 3 75 1.9E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 Pfam PF07729 FCD domain 92 217 1.5E-22 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_12955 ecd06446da423f8b12cb4c6fd81ffc28 227 SMART SM00895 92 218 2.6E-22 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_01565 9383fe70191090d3699c35456ca32df4 516 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 1.1E-29 T 14-10-2018 A4R43_01565 9383fe70191090d3699c35456ca32df4 516 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.1E-29 T 14-10-2018 A4R43_01565 9383fe70191090d3699c35456ca32df4 516 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 341 1.1E-29 T 14-10-2018 A4R43_01565 9383fe70191090d3699c35456ca32df4 516 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 1.1E-29 T 14-10-2018 A4R43_01565 9383fe70191090d3699c35456ca32df4 516 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 1.1E-29 T 14-10-2018 A4R43_01565 9383fe70191090d3699c35456ca32df4 516 Gene3D G3DSA:3.30.9.50 67 287 8.0E-107 T 14-10-2018 A4R43_01565 9383fe70191090d3699c35456ca32df4 516 Gene3D G3DSA:3.50.50.60 1 349 8.0E-107 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_01565 9383fe70191090d3699c35456ca32df4 516 Gene3D G3DSA:3.40.30.120 386 511 7.1E-24 T 14-10-2018 A4R43_01565 9383fe70191090d3699c35456ca32df4 516 Pfam PF01494 FAD binding domain 1 356 7.7E-89 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_01565 9383fe70191090d3699c35456ca32df4 516 SUPERFAMILY SSF51905 1 359 1.06E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_31655 149894a443d169eae4e78445bab4202d 428 Gene3D G3DSA:3.40.440.10 7 256 7.8E-96 T 14-10-2018 A4R43_31655 149894a443d169eae4e78445bab4202d 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 4.7E-162 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_31655 149894a443d169eae4e78445bab4202d 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 14-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_31655 149894a443d169eae4e78445bab4202d 428 SUPERFAMILY SSF52540 1 426 1.59E-167 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31655 149894a443d169eae4e78445bab4202d 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 200.832 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_31655 149894a443d169eae4e78445bab4202d 428 Gene3D G3DSA:1.10.300.10 101 200 7.8E-96 T 14-10-2018 A4R43_31655 149894a443d169eae4e78445bab4202d 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_31655 149894a443d169eae4e78445bab4202d 428 Pfam PF00709 Adenylosuccinate synthetase 4 422 3.2E-174 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_31655 149894a443d169eae4e78445bab4202d 428 Gene3D G3DSA:3.90.170.10 266 428 7.7E-69 T 14-10-2018 A4R43_31655 149894a443d169eae4e78445bab4202d 428 SMART SM00788 3 423 3.0E-276 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_11910 82ce1d888b0c159987e10404fe306a5b 439 Pfam PF13458 Periplasmic binding protein 45 400 5.1E-60 T 14-10-2018 IPR028081 Leucine-binding protein domain A4R43_11910 82ce1d888b0c159987e10404fe306a5b 439 Gene3D G3DSA:3.40.50.2300 164 312 7.8E-74 T 14-10-2018 A4R43_11910 82ce1d888b0c159987e10404fe306a5b 439 Gene3D G3DSA:3.40.50.2300 53 368 7.8E-74 T 14-10-2018 A4R43_11910 82ce1d888b0c159987e10404fe306a5b 439 SUPERFAMILY SSF53822 45 400 1.58E-62 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_30565 69cde85fcd8c09aba8adcc781cb5a880 688 SUPERFAMILY SSF101478 382 660 1.18E-13 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_30565 69cde85fcd8c09aba8adcc781cb5a880 688 Gene3D G3DSA:1.10.4080.10 513 669 3.7E-9 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_30565 69cde85fcd8c09aba8adcc781cb5a880 688 Pfam PF03747 ADP-ribosylglycohydrolase 506 643 1.3E-10 T 14-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 A4R43_30565 69cde85fcd8c09aba8adcc781cb5a880 688 Pfam PF15567 Immunity protein 35 20 98 3.0E-16 T 14-10-2018 IPR029082 Immunity protein 35 A4R43_37780 77561589589d7ad4e56a65d1600799a9 622 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 442 600 5.1E-26 T 14-10-2018 A4R43_37780 77561589589d7ad4e56a65d1600799a9 622 SUPERFAMILY SSF49899 414 604 3.25E-38 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_37780 77561589589d7ad4e56a65d1600799a9 622 Gene3D G3DSA:2.120.10.10 40 400 8.8E-88 T 14-10-2018 A4R43_37780 77561589589d7ad4e56a65d1600799a9 622 Pfam PF13088 BNR repeat-like domain 69 370 1.6E-31 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_37780 77561589589d7ad4e56a65d1600799a9 622 Gene3D G3DSA:2.60.120.200 412 603 3.1E-34 T 14-10-2018 A4R43_37780 77561589589d7ad4e56a65d1600799a9 622 SMART SM00560 461 597 0.0014 T 14-10-2018 IPR006558 LamG-like jellyroll fold A4R43_37780 77561589589d7ad4e56a65d1600799a9 622 SUPERFAMILY SSF50939 47 397 3.92E-73 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_23845 4eeb195f6bad644c4dce592d10666a1c 174 Pfam PF13302 Acetyltransferase (GNAT) domain 11 148 1.3E-21 T 14-10-2018 IPR000182 GNAT domain A4R43_23845 4eeb195f6bad644c4dce592d10666a1c 174 Gene3D G3DSA:3.40.630.30 5 161 7.7E-33 T 14-10-2018 A4R43_23845 4eeb195f6bad644c4dce592d10666a1c 174 SUPERFAMILY SSF55729 7 151 1.06E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_00500 a1f823d4618666a3286c2d922c04a34c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 2.1E-12 T 14-10-2018 A4R43_00500 a1f823d4618666a3286c2d922c04a34c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 19 41 2.1E-12 T 14-10-2018 A4R43_00500 a1f823d4618666a3286c2d922c04a34c 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 2.1E-12 T 14-10-2018 A4R43_00500 a1f823d4618666a3286c2d922c04a34c 400 SUPERFAMILY SSF51905 19 383 2.05E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00500 a1f823d4618666a3286c2d922c04a34c 400 Gene3D G3DSA:3.30.9.50 55 283 2.2E-62 T 14-10-2018 A4R43_00500 a1f823d4618666a3286c2d922c04a34c 400 Gene3D G3DSA:3.50.50.60 22 354 2.2E-62 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00500 a1f823d4618666a3286c2d922c04a34c 400 Pfam PF01494 FAD binding domain 19 181 8.5E-14 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_28435 9ad78cd492603f0756b93f8a78f40591 183 Gene3D G3DSA:3.40.220.10 1 180 1.5E-39 T 14-10-2018 A4R43_28435 9ad78cd492603f0756b93f8a78f40591 183 Pfam PF01661 Macro domain 40 166 1.5E-11 T 14-10-2018 IPR002589 Macro domain A4R43_28435 9ad78cd492603f0756b93f8a78f40591 183 SUPERFAMILY SSF52949 3 176 9.42E-25 T 14-10-2018 A4R43_28435 9ad78cd492603f0756b93f8a78f40591 183 SMART SM00506 23 168 1.3E-13 T 14-10-2018 IPR002589 Macro domain A4R43_05485 cee7f29809f6a63e5a7590d467c56a06 364 Gene3D G3DSA:3.30.1330.30 250 315 5.5E-5 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_05485 cee7f29809f6a63e5a7590d467c56a06 364 SUPERFAMILY SSF55315 243 363 8.24E-6 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_12940 5f45944bfde986f93694c97285deb2ac 476 Gene3D G3DSA:1.20.1720.10 1 185 1.1E-31 T 14-10-2018 A4R43_12940 5f45944bfde986f93694c97285deb2ac 476 Pfam PF07690 Major Facilitator Superfamily 3 392 4.7E-36 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_12940 5f45944bfde986f93694c97285deb2ac 476 SUPERFAMILY SSF103473 2 460 3.4E-46 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_12940 5f45944bfde986f93694c97285deb2ac 476 Gene3D G3DSA:1.20.1250.20 186 408 1.0E-15 T 14-10-2018 A4R43_08425 0f30410eac9d29d1dc70e3257012a6cf 328 Pfam PF00589 Phage integrase family 130 304 1.3E-19 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_08425 0f30410eac9d29d1dc70e3257012a6cf 328 Gene3D G3DSA:1.10.443.10 125 312 2.7E-31 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_08425 0f30410eac9d29d1dc70e3257012a6cf 328 SUPERFAMILY SSF56349 11 313 4.12E-36 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_08425 0f30410eac9d29d1dc70e3257012a6cf 328 Gene3D G3DSA:1.10.150.130 14 107 2.6E-7 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_01600 e62806c93a23ee823f5c3c484486d0e3 417 Pfam PF07690 Major Facilitator Superfamily 25 358 1.2E-40 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_01600 e62806c93a23ee823f5c3c484486d0e3 417 Gene3D G3DSA:1.20.1250.20 19 393 1.3E-44 T 14-10-2018 A4R43_01600 e62806c93a23ee823f5c3c484486d0e3 417 SUPERFAMILY SSF103473 10 395 2.75E-58 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_07790 8833213a68cda3467f782c2e2d4c35f4 295 SMART SM00833 155 265 1.4E-16 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4R43_07790 8833213a68cda3467f782c2e2d4c35f4 295 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 156 264 2.1E-12 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4R43_07790 8833213a68cda3467f782c2e2d4c35f4 295 SUPERFAMILY SSF90002 155 264 3.14E-7 T 14-10-2018 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 226 242 3.4E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 137 156 3.4E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 251 266 3.4E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 175 194 3.4E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 281 300 3.4E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 106 120 3.4E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 SUPERFAMILY SSF51569 1 308 4.54E-125 T 14-10-2018 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 226 238 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 Gene3D G3DSA:3.20.20.70 1 308 1.3E-128 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 PIRSF PIRSF001415 1 308 6.0E-137 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 SMART SM01004 1 307 1.9E-200 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_32935 9aa9de477bf1b59e7732b20d37e21ae6 308 Pfam PF00490 Delta-aminolevulinic acid dehydratase 1 306 1.5E-131 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4R43_28535 c5ca19a47a20a8374829d46020153181 194 Pfam PF06197 Protein of unknown function (DUF998) 3 184 6.2E-28 T 14-10-2018 IPR009339 Protein of unknown function DUF998 A4R43_30870 fbd5d989dd331434d90f7dff64f167cf 314 Gene3D G3DSA:3.40.50.300 1 279 1.3E-64 T 14-10-2018 A4R43_30870 fbd5d989dd331434d90f7dff64f167cf 314 SMART SM00382 30 214 1.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_30870 fbd5d989dd331434d90f7dff64f167cf 314 SUPERFAMILY SSF52540 10 229 1.02E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30870 fbd5d989dd331434d90f7dff64f167cf 314 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_30870 fbd5d989dd331434d90f7dff64f167cf 314 Pfam PF00005 ABC transporter 22 165 5.8E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_13340 6497106cefb18e1799f43b44e94a19a8 95 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 68 94 3.2E-6 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_13340 6497106cefb18e1799f43b44e94a19a8 95 SUPERFAMILY SSF54736 67 94 7.32E-5 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4R43_13340 6497106cefb18e1799f43b44e94a19a8 95 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 95 0.003 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_13340 6497106cefb18e1799f43b44e94a19a8 95 Gene3D G3DSA:3.30.1390.10 61 95 3.5E-8 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 SMART SM00421 154 211 2.2E-27 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 Pfam PF00072 Response regulator receiver domain 7 119 2.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 Gene3D G3DSA:3.40.50.12740 5 217 2.2E-69 T 14-10-2018 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 7.8E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 SMART SM00448 5 120 9.4E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 SUPERFAMILY SSF46894 146 217 7.14E-24 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_00855 4803524a4624c1ba4dd51c1a9212e8ff 218 SUPERFAMILY SSF52172 4 138 5.69E-31 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_17910 f6df20c690e14a995e4b00b2f2585e5b 292 SUPERFAMILY SSF52151 10 209 8.55E-51 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_17910 f6df20c690e14a995e4b00b2f2585e5b 292 Gene3D G3DSA:3.40.1090.10 104 202 3.1E-16 T 14-10-2018 A4R43_17910 f6df20c690e14a995e4b00b2f2585e5b 292 Gene3D G3DSA:3.40.1090.10 7 100 3.2E-17 T 14-10-2018 A4R43_17910 f6df20c690e14a995e4b00b2f2585e5b 292 Pfam PF01734 Patatin-like phospholipase 13 185 1.1E-27 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A4R43_41015 e70eb39a6bee357d218d5f28f266eee0 199 Gene3D G3DSA:1.10.357.10 1 197 6.2E-46 T 14-10-2018 A4R43_41015 e70eb39a6bee357d218d5f28f266eee0 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 7.7E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_41015 e70eb39a6bee357d218d5f28f266eee0 199 SUPERFAMILY SSF48498 83 196 3.62E-15 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_41015 e70eb39a6bee357d218d5f28f266eee0 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.8E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_41015 e70eb39a6bee357d218d5f28f266eee0 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.8E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_41015 e70eb39a6bee357d218d5f28f266eee0 199 SUPERFAMILY SSF46689 6 75 3.44E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_41015 e70eb39a6bee357d218d5f28f266eee0 199 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 86 197 3.1E-11 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 Pfam PF12848 ABC transporter 191 265 3.9E-6 T 14-10-2018 IPR032781 ABC-transporter extension domain A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 SUPERFAMILY SSF52540 5 203 2.41E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 Pfam PF16326 ABC transporter C-terminal domain 527 586 7.1E-8 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 SUPERFAMILY SSF52540 272 483 5.89E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 Pfam PF00005 ABC transporter 299 433 2.0E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 SMART SM00382 308 477 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 SMART SM00382 29 228 3.0E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 Gene3D G3DSA:3.40.50.300 2 233 2.7E-57 T 14-10-2018 A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 Gene3D G3DSA:3.40.50.300 264 510 1.4E-58 T 14-10-2018 A4R43_24060 e8be8c345a63353228b8e4eef73dae27 589 Pfam PF00005 ABC transporter 20 152 3.0E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_12160 529ac1303fc718ba4ab2b6aea4c3c5a7 255 Pfam PF14011 EspG family 9 248 5.7E-61 T 14-10-2018 IPR025734 EspG family A4R43_11195 561ab23c409ddc3e8244207473d9a34a 457 SUPERFAMILY SSF54631 212 353 3.16E-29 T 14-10-2018 A4R43_11195 561ab23c409ddc3e8244207473d9a34a 457 SMART SM01091 358 436 6.9E-23 T 14-10-2018 IPR005170 Transporter-associated domain A4R43_11195 561ab23c409ddc3e8244207473d9a34a 457 Pfam PF00571 CBS domain 289 341 9.4E-6 T 14-10-2018 IPR000644 CBS domain A4R43_11195 561ab23c409ddc3e8244207473d9a34a 457 Gene3D G3DSA:3.30.465.10 352 436 1.3E-21 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_11195 561ab23c409ddc3e8244207473d9a34a 457 Pfam PF01595 Domain of unknown function DUF21 14 205 3.0E-31 T 14-10-2018 IPR002550 CNNM, transmembrane domain A4R43_11195 561ab23c409ddc3e8244207473d9a34a 457 Pfam PF03471 Transporter associated domain 359 434 1.1E-22 T 14-10-2018 IPR005170 Transporter-associated domain A4R43_11195 561ab23c409ddc3e8244207473d9a34a 457 SUPERFAMILY SSF56176 358 439 1.15E-20 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_11195 561ab23c409ddc3e8244207473d9a34a 457 Gene3D G3DSA:3.10.580.10 202 351 9.5E-47 T 14-10-2018 A4R43_20575 7e59c04c29bfc8f2b606481c906465e0 446 Gene3D G3DSA:3.40.50.720 220 366 1.0E-222 T 14-10-2018 A4R43_20575 7e59c04c29bfc8f2b606481c906465e0 446 SUPERFAMILY SSF51735 196 387 3.78E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_20575 7e59c04c29bfc8f2b606481c906465e0 446 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 116 191 1.3E-5 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_20575 7e59c04c29bfc8f2b606481c906465e0 446 SMART SM00829 50 416 1.7E-9 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_20575 7e59c04c29bfc8f2b606481c906465e0 446 Gene3D G3DSA:3.90.180.10 16 434 1.0E-222 T 14-10-2018 A4R43_20575 7e59c04c29bfc8f2b606481c906465e0 446 Pfam PF00107 Zinc-binding dehydrogenase 237 381 1.7E-36 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_20575 7e59c04c29bfc8f2b606481c906465e0 446 SUPERFAMILY SSF50129 51 231 1.4E-27 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_20575 7e59c04c29bfc8f2b606481c906465e0 446 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 32 429 4.4E-185 T 14-10-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 SMART SM00862 16 89 1.4E-13 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 Gene3D G3DSA:1.10.10.10 1 91 7.7E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 SUPERFAMILY SSF48452 91 259 5.48E-38 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 SUPERFAMILY SSF46894 2 89 6.52E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 SUPERFAMILY SSF52540 257 530 3.01E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 SUPERFAMILY SSF48452 780 887 9.66E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 Gene3D G3DSA:1.25.40.10 751 1023 1.6E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 SMART SM01043 93 238 4.8E-46 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 Gene3D G3DSA:1.25.40.10 92 260 3.3E-48 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 89 4.7E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 Pfam PF03704 Bacterial transcriptional activator domain 93 238 1.1E-41 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 PRINTS PR00364 Disease resistance protein signature 283 298 7.7E-6 T 14-10-2018 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 PRINTS PR00364 Disease resistance protein signature 362 376 7.7E-6 T 14-10-2018 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 PRINTS PR00364 Disease resistance protein signature 465 479 7.7E-6 T 14-10-2018 A4R43_26735 0715f98a309d877f0e0e4ad7e7aa518a 1060 Gene3D G3DSA:3.40.50.300 261 393 4.7E-5 T 14-10-2018 A4R43_10900 e3d103b30ec68439929e40a31c5dea8f 190 Pfam PF08241 Methyltransferase domain 50 149 7.0E-18 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_10900 e3d103b30ec68439929e40a31c5dea8f 190 Gene3D G3DSA:3.40.50.150 14 182 2.0E-28 T 14-10-2018 A4R43_10900 e3d103b30ec68439929e40a31c5dea8f 190 SUPERFAMILY SSF53335 31 169 6.35E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 Pfam PF00672 HAMP domain 114 162 2.2E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 SUPERFAMILY SSF55874 223 381 3.67E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 Gene3D G3DSA:1.10.287.130 117 233 8.2E-28 T 14-10-2018 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 SUPERFAMILY SSF47384 150 233 2.16E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 Pfam PF00512 His Kinase A (phospho-acceptor) domain 167 233 8.5E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 275 382 7.7E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 SMART SM00387 275 384 9.5E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 SMART SM00304 113 166 6.9E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 Gene3D G3DSA:3.30.565.10 236 384 1.9E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 362 5.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 323 5.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 337 5.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 SUPERFAMILY SSF158472 114 163 5.62E-9 T 14-10-2018 A4R43_25725 d0d6ac82773cc20c5257a8dc4d2e66ec 384 SMART SM00388 167 233 3.3E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_09615 8bc3036301378cda2a2403db355c841d 457 Pfam PF03315 Serine dehydratase beta chain 4 157 3.0E-58 T 14-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A4R43_09615 8bc3036301378cda2a2403db355c841d 457 Pfam PF03313 Serine dehydratase alpha chain 188 451 1.7E-102 T 14-10-2018 IPR005130 Serine dehydratase-like, alpha subunit A4R43_09615 8bc3036301378cda2a2403db355c841d 457 SUPERFAMILY SSF143548 17 159 7.32E-43 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A4R43_09615 8bc3036301378cda2a2403db355c841d 457 Gene3D G3DSA:3.30.1330.90 11 161 1.3E-51 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A4R43_09615 8bc3036301378cda2a2403db355c841d 457 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 454 5.3E-203 T 14-10-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A4R43_14450 4d2d25309dd63c1222934ba6484deadf 314 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 87 225 1.1E-29 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_14450 4d2d25309dd63c1222934ba6484deadf 314 Gene3D G3DSA:1.10.260.150 66 295 5.4E-46 T 14-10-2018 A4R43_14450 4d2d25309dd63c1222934ba6484deadf 314 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 86 225 9.4E-25 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_17720 4ff635bcd57f3b65b4a50aa521d06fb8 315 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 141 255 4.7E-16 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_17720 4ff635bcd57f3b65b4a50aa521d06fb8 315 Gene3D G3DSA:2.60.40.2600 136 312 8.0E-39 T 14-10-2018 A4R43_17720 4ff635bcd57f3b65b4a50aa521d06fb8 315 SUPERFAMILY SSF49503 134 276 1.89E-37 T 14-10-2018 IPR008972 Cupredoxin A4R43_17720 4ff635bcd57f3b65b4a50aa521d06fb8 315 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 196 249 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_17720 4ff635bcd57f3b65b4a50aa521d06fb8 315 Gene3D G3DSA:1.10.287.90 47 129 4.1E-12 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_17720 4ff635bcd57f3b65b4a50aa521d06fb8 315 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 49 265 1.2E-44 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_17720 4ff635bcd57f3b65b4a50aa521d06fb8 315 SUPERFAMILY SSF81464 24 126 3.6E-18 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 3.6E-80 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 Pfam PF00633 Helix-hairpin-helix motif 2 27 5.4E-6 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 SMART SM00493 79 164 3.7E-15 T 14-10-2018 IPR006171 TOPRIM domain A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 100.213 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 14-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 SUPERFAMILY SSF111304 3 198 3.66E-69 T 14-10-2018 IPR023627 Recombination protein RecR A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 Pfam PF13662 Toprim domain 80 171 4.8E-25 T 14-10-2018 IPR006171 TOPRIM domain A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 Gene3D G3DSA:1.10.8.420 2 51 5.3E-17 T 14-10-2018 A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 Pfam PF02132 RecR protein 40 77 1.6E-13 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger A4R43_27420 75fc42c6d4d35572b1066bd6516b7873 198 Gene3D G3DSA:3.40.1360.10 76 198 7.3E-45 T 14-10-2018 A4R43_39325 aa8204e08211e94fd20f8e506e6d3264 133 SUPERFAMILY SSF81301 7 117 3.11E-40 T 14-10-2018 A4R43_39325 aa8204e08211e94fd20f8e506e6d3264 133 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 13 108 3.4E-33 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A4R43_39325 aa8204e08211e94fd20f8e506e6d3264 133 Pfam PF02410 Ribosomal silencing factor during starvation 14 108 4.3E-24 T 14-10-2018 A4R43_39325 aa8204e08211e94fd20f8e506e6d3264 133 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 109 23.869 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A4R43_39325 aa8204e08211e94fd20f8e506e6d3264 133 Gene3D G3DSA:3.30.460.10 1 112 1.0E-40 T 14-10-2018 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 SUPERFAMILY SSF55874 247 396 1.12E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 SUPERFAMILY SSF47384 162 243 2.55E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 Pfam PF00672 HAMP domain 121 174 4.5E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 Gene3D G3DSA:3.30.565.10 246 396 8.5E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 SMART SM00304 120 178 1.7E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 Gene3D G3DSA:1.10.287.130 124 245 2.0E-24 T 14-10-2018 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 SMART SM00388 179 245 4.0E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 242 1.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 SUPERFAMILY SSF158472 122 175 1.57E-6 T 14-10-2018 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 396 7.6E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 352 7.6E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 377 7.6E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 338 7.6E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 396 7.8E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25185 05715389c0dd05a37ca3244b9dad1ab4 397 SMART SM00387 287 397 9.0E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_07640 a94ecb36ef807ef27fb4845edee121a7 351 Gene3D G3DSA:3.40.640.10 2 236 4.9E-83 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_07640 a94ecb36ef807ef27fb4845edee121a7 351 Gene3D G3DSA:3.90.1150.10 237 350 4.4E-21 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_07640 a94ecb36ef807ef27fb4845edee121a7 351 PIRSF PIRSF000390 1 351 2.2E-93 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_07640 a94ecb36ef807ef27fb4845edee121a7 351 SUPERFAMILY SSF53383 5 350 3.99E-98 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_07640 a94ecb36ef807ef27fb4845edee121a7 351 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 346 1.3E-97 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 Gene3D G3DSA:1.10.10.10 843 906 5.7E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 849 863 2.8E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 879 891 2.8E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 863 879 2.8E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 Pfam PF00196 Bacterial regulatory proteins, luxR family 848 899 1.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 ProSitePatterns PS00622 LuxR-type HTH domain signature. 863 890 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 SUPERFAMILY SSF52540 27 203 1.87E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 Gene3D G3DSA:1.25.40.10 512 842 3.7E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 SUPERFAMILY SSF46894 837 899 2.38E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 Pfam PF13191 AAA ATPase domain 12 158 1.1E-14 T 14-10-2018 A4R43_38485 b79cb9c43f81cb1cfaf465ecf6c5188b 911 SMART SM00421 846 903 7.3E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_04610 209299e4c2216f602b44233c218c62d1 409 Pfam PF02378 Phosphotransferase system, EIIC 21 324 7.7E-70 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A4R43_19055 d5603bbb46a7cce72e4e1d9072168f1c 140 Pfam PF12098 Protein of unknown function (DUF3574) 38 140 5.0E-35 T 14-10-2018 IPR021957 Protein of unknown function DUF3574 A4R43_34025 8b13d6eb10b1ada1b0360e6bdad47966 538 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 1 518 1.1E-104 T 14-10-2018 IPR007795 Type VII secretion system EccB A4R43_34025 8b13d6eb10b1ada1b0360e6bdad47966 538 Gene3D G3DSA:2.40.50.900 55 166 2.5E-11 T 14-10-2018 A4R43_34025 8b13d6eb10b1ada1b0360e6bdad47966 538 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 116 500 8.0E-55 T 14-10-2018 IPR007795 Type VII secretion system EccB A4R43_34025 8b13d6eb10b1ada1b0360e6bdad47966 538 Gene3D G3DSA:2.40.50.910 272 353 3.1E-8 T 14-10-2018 A4R43_12500 48efcabc25301d5f65a34a626975bc56 472 Gene3D G3DSA:3.90.1300.10 1 472 5.6E-125 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_12500 48efcabc25301d5f65a34a626975bc56 472 Pfam PF01425 Amidase 24 458 4.9E-102 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_12500 48efcabc25301d5f65a34a626975bc56 472 SUPERFAMILY SSF75304 2 469 2.62E-119 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_12500 48efcabc25301d5f65a34a626975bc56 472 ProSitePatterns PS00571 Amidases signature. 151 182 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4R43_34500 8d9c8255e204a448b6fcf918346ececd 141 SUPERFAMILY SSF55729 1 133 6.65E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_34500 8d9c8255e204a448b6fcf918346ececd 141 Pfam PF13508 Acetyltransferase (GNAT) domain 56 128 3.9E-11 T 14-10-2018 IPR000182 GNAT domain A4R43_34500 8d9c8255e204a448b6fcf918346ececd 141 Gene3D G3DSA:3.40.630.30 3 139 2.0E-23 T 14-10-2018 A4R43_22405 f74337b55bc75489e9a4b1a6dbee7eab 114 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_22405 f74337b55bc75489e9a4b1a6dbee7eab 114 Pfam PF13411 MerR HTH family regulatory protein 2 67 3.6E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_22405 f74337b55bc75489e9a4b1a6dbee7eab 114 Gene3D G3DSA:1.10.1660.10 1 112 3.6E-28 T 14-10-2018 A4R43_22405 f74337b55bc75489e9a4b1a6dbee7eab 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.6E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_22405 f74337b55bc75489e9a4b1a6dbee7eab 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.6E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_22405 f74337b55bc75489e9a4b1a6dbee7eab 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.6E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_22405 f74337b55bc75489e9a4b1a6dbee7eab 114 SMART SM00422 1 69 1.0E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_22405 f74337b55bc75489e9a4b1a6dbee7eab 114 SUPERFAMILY SSF46955 1 110 2.12E-25 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 SUPERFAMILY SSF52540 180 447 2.64E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Gene3D G3DSA:3.40.50.300 176 363 1.7E-66 T 14-10-2018 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Gene3D G3DSA:3.40.50.300 483 730 1.3E-95 T 14-10-2018 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 SUPERFAMILY SSF52540 502 818 5.63E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Pfam PF02151 UvrB/uvrC motif 440 468 3.1E-7 T 14-10-2018 IPR001943 UVR domain GO:0005515 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 732 812 1.4E-24 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Gene3D G3DSA:1.10.1780.10 35 169 6.3E-21 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 SMART SM00382 219 364 1.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 SMART SM00382 553 695 6.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Pfam PF07724 AAA domain (Cdc48 subfamily) 552 726 2.4E-50 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Gene3D G3DSA:1.10.8.60 732 826 1.7E-26 T 14-10-2018 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 SUPERFAMILY SSF81923 37 167 6.59E-14 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 664 678 4.1E-40 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 631 649 4.1E-40 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 557 575 4.1E-40 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 602 620 4.1E-40 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 SMART SM01086 732 821 8.7E-36 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 587 605 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 48 86 8.0E-4 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 118 164 9.0E-13 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Gene3D G3DSA:3.40.50.300 364 482 5.8E-36 T 14-10-2018 A4R43_05475 b5cb2f373ca710b644ef7cb3d202be06 832 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 224 336 6.8E-11 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_05470 a1e7c21ebf5c7b6f9a1cb65067a3189c 307 SUPERFAMILY SSF53613 14 284 2.81E-37 T 14-10-2018 IPR029056 Ribokinase-like A4R43_05470 a1e7c21ebf5c7b6f9a1cb65067a3189c 307 PIRSF PIRSF000535 6 301 2.0E-37 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A4R43_05470 a1e7c21ebf5c7b6f9a1cb65067a3189c 307 Pfam PF00294 pfkB family carbohydrate kinase 20 282 1.6E-27 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_05470 a1e7c21ebf5c7b6f9a1cb65067a3189c 307 Gene3D G3DSA:3.40.1190.20 3 306 1.5E-50 T 14-10-2018 IPR029056 Ribokinase-like A4R43_05470 a1e7c21ebf5c7b6f9a1cb65067a3189c 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 239 252 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 64 81 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 28 43 2.7E-25 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 69 81 2.7E-25 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 137 152 2.7E-25 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 124 136 2.7E-25 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 109 124 2.7E-25 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 Gene3D G3DSA:2.40.100.10 11 180 1.2E-73 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 16 177 4.1E-45 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 PIRSF PIRSF001467 6 179 3.9E-56 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A4R43_29155 0949038f241531083693bef0ca6e6f6c 180 SUPERFAMILY SSF50891 14 177 4.68E-61 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_26750 2eb37f847c57cfbf125b1a5e17bd87f6 192 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 7 183 1.9E-43 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_26750 2eb37f847c57cfbf125b1a5e17bd87f6 192 Gene3D G3DSA:1.20.120.450 3 131 4.2E-9 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_26750 2eb37f847c57cfbf125b1a5e17bd87f6 192 SUPERFAMILY SSF109854 3 133 7.32E-17 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_26750 2eb37f847c57cfbf125b1a5e17bd87f6 192 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 127 2.4E-11 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_26750 2eb37f847c57cfbf125b1a5e17bd87f6 192 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 183 9.2E-26 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_39925 c6d9221d01aa1b59d6571b9791f57004 317 Gene3D G3DSA:3.50.30.50 63 317 2.1E-20 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_39925 c6d9221d01aa1b59d6571b9791f57004 317 Pfam PF04199 Putative cyclase 81 248 5.2E-23 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_39925 c6d9221d01aa1b59d6571b9791f57004 317 SUPERFAMILY SSF102198 97 316 2.62E-20 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_27455 9eea9cc336c0dd4f4fd82ab2515810c3 512 Pfam PF09423 PhoD-like phosphatase 157 466 3.6E-86 T 14-10-2018 IPR018946 Alkaline phosphatase D-related A4R43_27455 9eea9cc336c0dd4f4fd82ab2515810c3 512 SUPERFAMILY SSF56300 155 469 8.22E-24 T 14-10-2018 A4R43_27455 9eea9cc336c0dd4f4fd82ab2515810c3 512 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 21 0.0015 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4R43_27455 9eea9cc336c0dd4f4fd82ab2515810c3 512 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 52 146 2.4E-29 T 14-10-2018 IPR032093 Phospholipase D, N-terminal A4R43_27455 9eea9cc336c0dd4f4fd82ab2515810c3 512 Gene3D G3DSA:3.60.21.70 149 511 5.7E-111 T 14-10-2018 IPR038607 PhoD-like superfamily A4R43_27455 9eea9cc336c0dd4f4fd82ab2515810c3 512 Gene3D G3DSA:2.60.40.380 42 148 1.7E-35 T 14-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 A4R43_00835 4dd14713b4d530f0ea98b67d33121576 195 SUPERFAMILY SSF51182 66 176 3.71E-21 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_00835 4dd14713b4d530f0ea98b67d33121576 195 Pfam PF07883 Cupin domain 115 177 9.4E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_00835 4dd14713b4d530f0ea98b67d33121576 195 SMART SM00530 15 70 3.7E-19 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_00835 4dd14713b4d530f0ea98b67d33121576 195 Gene3D G3DSA:1.10.260.40 10 81 1.6E-19 T 14-10-2018 A4R43_00835 4dd14713b4d530f0ea98b67d33121576 195 SUPERFAMILY SSF47413 11 75 6.97E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_00835 4dd14713b4d530f0ea98b67d33121576 195 Gene3D G3DSA:2.60.120.10 82 178 1.4E-11 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_00835 4dd14713b4d530f0ea98b67d33121576 195 Pfam PF01381 Helix-turn-helix 16 70 1.2E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_08855 ab0068219cba703a12720aa338c64223 751 Gene3D G3DSA:1.20.1580.10 94 335 1.3E-161 T 14-10-2018 A4R43_08855 ab0068219cba703a12720aa338c64223 751 Gene3D G3DSA:1.20.1580.10 543 581 1.0E-105 T 14-10-2018 A4R43_08855 ab0068219cba703a12720aa338c64223 751 Gene3D G3DSA:3.40.50.300 461 745 1.0E-105 T 14-10-2018 A4R43_08855 ab0068219cba703a12720aa338c64223 751 SUPERFAMILY SSF52540 464 723 2.86E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08855 ab0068219cba703a12720aa338c64223 751 SMART SM00382 26 412 3.9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08855 ab0068219cba703a12720aa338c64223 751 SMART SM00382 475 715 0.28 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08855 ab0068219cba703a12720aa338c64223 751 SUPERFAMILY SSF52540 4 427 1.05E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08855 ab0068219cba703a12720aa338c64223 751 Pfam PF00005 ABC transporter 466 669 5.8E-12 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_08855 ab0068219cba703a12720aa338c64223 751 Gene3D G3DSA:1.10.8.280 148 257 1.3E-161 T 14-10-2018 A4R43_08855 ab0068219cba703a12720aa338c64223 751 ProSitePatterns PS00211 ABC transporters family signature. 642 656 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_08855 ab0068219cba703a12720aa338c64223 751 Gene3D G3DSA:3.40.50.300 8 436 1.3E-161 T 14-10-2018 A4R43_19455 734067fa964eca06af8a208e71bcdc54 267 SUPERFAMILY SSF160920 9 257 3.79E-110 T 14-10-2018 IPR038021 Putative hydro-lyase A4R43_19455 734067fa964eca06af8a208e71bcdc54 267 Gene3D G3DSA:3.40.1640.10 21 252 3.6E-93 T 14-10-2018 A4R43_19455 734067fa964eca06af8a208e71bcdc54 267 Gene3D G3DSA:3.30.2040.10 124 236 3.6E-93 T 14-10-2018 A4R43_19455 734067fa964eca06af8a208e71bcdc54 267 PIRSF PIRSF029755 1 265 8.3E-116 T 14-10-2018 IPR016938 Uncharacterised protein family UPF0317 A4R43_19455 734067fa964eca06af8a208e71bcdc54 267 Hamap MF_01830 Putative hydro-lyase . 12 264 52.32 T 14-10-2018 IPR016938 Uncharacterised protein family UPF0317 A4R43_19455 734067fa964eca06af8a208e71bcdc54 267 Pfam PF07286 Protein of unknown function (DUF1445) 114 256 4.9E-65 T 14-10-2018 IPR009906 D-glutamate cyclase A4R43_23990 3a6d518e5f62570e2e90f6e1d5824e9d 167 Gene3D G3DSA:3.40.50.850 2 166 7.8E-38 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_23990 3a6d518e5f62570e2e90f6e1d5824e9d 167 Pfam PF00857 Isochorismatase family 8 161 1.8E-32 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4R43_23990 3a6d518e5f62570e2e90f6e1d5824e9d 167 SUPERFAMILY SSF52499 2 164 2.35E-41 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 SUPERFAMILY SSF81665 84 324 3.53E-13 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 SUPERFAMILY SSF56784 328 620 2.93E-50 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 104 601 3.6E-79 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 535 9.6E-42 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 63 601 2.2E-119 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00941 Cadmium-transporting ATPase signature 116 136 1.2E-6 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00941 Cadmium-transporting ATPase signature 216 230 1.2E-6 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00941 Cadmium-transporting ATPase signature 197 213 1.2E-6 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 SUPERFAMILY SSF81653 134 231 4.45E-23 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 Gene3D G3DSA:3.40.1110.10 341 452 3.9E-82 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 82 623 4.8E-168 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 332 338 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 Gene3D G3DSA:2.70.150.20 125 236 4.9E-31 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 330 344 1.7E-29 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 467 477 1.7E-29 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 181 195 1.7E-29 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 445 456 1.7E-29 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 521 540 1.7E-29 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 557 1.7E-29 T 14-10-2018 A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 Gene3D G3DSA:3.40.50.1000 311 573 3.9E-82 T 14-10-2018 IPR023214 HAD superfamily A4R43_01725 54d2c8edd97fd9ab93e3eaf2de3e6d91 656 Pfam PF00122 E1-E2 ATPase 132 309 1.2E-44 T 14-10-2018 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 5.0E-22 T 14-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 154 1.0E-44 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 Hamap MF_00173 Arginine repressor [argR]. 1 158 60.56 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 PRINTS PR01467 Bacterial arginine repressor signature 94 107 2.1E-25 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.1E-25 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 PRINTS PR01467 Bacterial arginine repressor signature 124 139 2.1E-25 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.1E-25 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 SUPERFAMILY SSF55252 86 153 1.96E-17 T 14-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 Gene3D G3DSA:1.10.10.10 1 74 2.5E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 94 151 3.0E-17 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 SUPERFAMILY SSF46785 1 70 4.72E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 Pfam PF02863 Arginine repressor, C-terminal domain 86 152 3.3E-24 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A4R43_14305 81194d0a008bd0bdb0a51dd187c417ee 163 Gene3D G3DSA:3.30.1360.40 77 155 2.4E-29 T 14-10-2018 A4R43_39765 bbc2c761500dcb63a36212bb30c66188 300 Gene3D G3DSA:3.40.50.300 1 231 1.2E-59 T 14-10-2018 A4R43_39765 bbc2c761500dcb63a36212bb30c66188 300 SMART SM00382 32 216 3.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_39765 bbc2c761500dcb63a36212bb30c66188 300 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_39765 bbc2c761500dcb63a36212bb30c66188 300 Pfam PF00005 ABC transporter 24 160 2.0E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_39765 bbc2c761500dcb63a36212bb30c66188 300 SUPERFAMILY SSF52540 6 224 6.4E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 174 180 - T 14-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 7 184 4.8E-52 T 14-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 Gene3D G3DSA:3.30.360.10 174 455 1.3E-156 T 14-10-2018 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 PIRSF PIRSF000110 1 469 1.9E-148 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 3 468 75.889 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 SUPERFAMILY SSF55347 174 465 3.27E-91 T 14-10-2018 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 3 462 9.2E-143 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 SUPERFAMILY SSF51735 3 187 5.91E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 Gene3D G3DSA:3.40.50.720 6 420 1.3E-156 T 14-10-2018 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 192 1.8E-41 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 216 233 1.8E-41 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 311 337 1.8E-41 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 140 153 1.8E-41 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 234 250 1.8E-41 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_19300 74236e9c42f9c868d81589cd3afe6beb 470 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 186 463 1.5E-88 T 14-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4R43_08955 0189066a4459e2cbf6f60b5e3d19f608 319 SUPERFAMILY SSF48239 33 315 2.04E-11 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4R43_32595 88a10691e31ae6940fa973a5d20d3df1 253 Gene3D G3DSA:3.60.40.10 6 250 2.1E-5 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_32595 88a10691e31ae6940fa973a5d20d3df1 253 SUPERFAMILY SSF81606 20 225 4.71E-5 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 51 2.5E-10 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 Pfam PF00384 Molybdopterin oxidoreductase 59 428 4.2E-31 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 SUPERFAMILY SSF50692 587 709 2.12E-26 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 Gene3D G3DSA:3.40.50.740 66 474 5.2E-91 T 14-10-2018 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 SUPERFAMILY SSF53706 2 567 3.27E-112 T 14-10-2018 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 Gene3D G3DSA:2.40.40.20 575 710 3.6E-22 T 14-10-2018 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 Gene3D G3DSA:2.20.25.90 1 61 1.7E-14 T 14-10-2018 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 Gene3D G3DSA:3.40.228.10 134 330 5.2E-91 T 14-10-2018 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 Pfam PF01568 Molydopterin dinucleotide binding domain 587 702 1.7E-19 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4R43_36990 a21debbc11bc4ac973edb55b119135bb 711 SMART SM00926 1 55 1.5E-14 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 8.1E-35 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 7.0E-16 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 SUPERFAMILY SSF110324 2 81 1.01E-31 T 14-10-2018 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 Gene3D G3DSA:2.40.50.100 21 85 2.0E-27 T 14-10-2018 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 27.509 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 Pfam PF01016 Ribosomal L27 protein 2 80 1.3E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 9.3E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 9.3E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39260 81a47e868deae32bfdca09a1a5776d0b 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 9.3E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 Pfam PF01022 Bacterial regulatory protein, arsR family 41 88 8.4E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 SMART SM00418 34 112 2.1E-24 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 Gene3D G3DSA:1.10.10.10 1 111 6.5E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 4.7E-22 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 4.7E-22 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 4.7E-22 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 4.7E-22 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 SUPERFAMILY SSF46785 21 102 2.35E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01730 a91d2f00d3022e0b0be2d305ebff8f82 115 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 14-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 SUPERFAMILY SSF54665 4 137 1.44E-34 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 SUPERFAMILY SSF56003 146 717 2.49E-140 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 Gene3D G3DSA:3.30.365.10 154 377 3.8E-56 T 14-10-2018 A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 Gene3D G3DSA:3.30.365.10 178 273 3.8E-56 T 14-10-2018 A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 19 124 6.0E-24 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 SMART SM01008 19 126 1.5E-31 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 150 660 3.5E-106 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 Gene3D G3DSA:3.90.1170.50 1 125 3.7E-34 T 14-10-2018 A4R43_02660 369dc34df723ec1d417d0b740e00377f 717 Gene3D G3DSA:3.30.365.20 388 717 8.3E-77 T 14-10-2018 A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 SUPERFAMILY SSF49299 727 813 2.35E-16 T 14-10-2018 IPR035986 PKD domain superfamily A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Pfam PF07995 Glucose / Sorbosone dehydrogenase 283 541 1.0E-29 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 SUPERFAMILY SSF52317 37 264 1.58E-41 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Gene3D G3DSA:2.60.120.260 923 1058 2.3E-22 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 SMART SM00606 920 1059 6.0E-17 T 14-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 SUPERFAMILY SSF49299 1071 1150 6.15E-17 T 14-10-2018 IPR035986 PKD domain superfamily A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Gene3D G3DSA:3.40.50.880 23 262 8.5E-78 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 SMART SM00089 730 814 2.5E-13 T 14-10-2018 IPR022409 PKD/Chitinase domain A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 SMART SM00089 1070 1149 4.7E-15 T 14-10-2018 IPR022409 PKD/Chitinase domain A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Pfam PF03422 Carbohydrate binding module (family 6) 938 1058 2.2E-16 T 14-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Pfam PF06283 Trehalose utilisation 40 256 8.4E-72 T 14-10-2018 IPR029010 ThuA-like domain A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Gene3D G3DSA:2.60.40.10 1067 1151 4.6E-17 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Gene3D G3DSA:2.60.40.10 719 812 1.1E-15 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 SUPERFAMILY SSF49785 924 1057 1.33E-14 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Pfam PF00801 PKD domain 1073 1139 3.6E-11 T 14-10-2018 IPR000601 PKD domain A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Pfam PF00801 PKD domain 745 800 2.0E-11 T 14-10-2018 IPR000601 PKD domain A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 SUPERFAMILY SSF50952 267 539 2.09E-17 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_18965 57fbc84281e1d4cf192b5e451cf0c070 1151 Gene3D G3DSA:2.120.10.30 263 643 1.1E-71 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_03470 954623393b68b844a7632c1229f2a49a 292 SUPERFAMILY SSF48179 163 291 1.93E-36 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_03470 954623393b68b844a7632c1229f2a49a 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 162 9.2E-52 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_03470 954623393b68b844a7632c1229f2a49a 292 Gene3D G3DSA:3.40.50.720 1 161 9.2E-55 T 14-10-2018 A4R43_03470 954623393b68b844a7632c1229f2a49a 292 PIRSF PIRSF000103 1 292 7.0E-78 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_03470 954623393b68b844a7632c1229f2a49a 292 SUPERFAMILY SSF51735 6 163 5.0E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03470 954623393b68b844a7632c1229f2a49a 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 281 9.1E-36 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A4R43_03470 954623393b68b844a7632c1229f2a49a 292 Gene3D G3DSA:1.10.1040.10 162 292 7.1E-38 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_03470 954623393b68b844a7632c1229f2a49a 292 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_41800 4b87638769a2668aea3b8e0669dafb04 124 Pfam PF03965 Penicillinase repressor 7 118 5.5E-26 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A4R43_41800 4b87638769a2668aea3b8e0669dafb04 124 Gene3D G3DSA:1.10.10.10 2 73 2.0E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41800 4b87638769a2668aea3b8e0669dafb04 124 SUPERFAMILY SSF46785 6 121 1.13E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 194 1.3E-33 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 Gene3D G3DSA:3.40.50.970 381 580 2.1E-36 T 14-10-2018 A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 Gene3D G3DSA:3.40.50.970 1 206 9.1E-29 T 14-10-2018 A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 2 590 3.0E-242 T 14-10-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 218 350 1.1E-30 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 SUPERFAMILY SSF52518 2 207 3.93E-28 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 SUPERFAMILY SSF52518 387 577 1.01E-39 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 429 567 8.4E-27 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 SUPERFAMILY SSF52467 179 377 2.95E-39 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_19250 3a826e7275ae5d09f2be2a2731efc456 607 Gene3D G3DSA:3.40.50.1220 212 380 4.9E-37 T 14-10-2018 A4R43_09865 875d0fa72a6c74582aca65f710a57e3d 200 Gene3D G3DSA:1.10.357.10 3 199 1.7E-35 T 14-10-2018 A4R43_09865 875d0fa72a6c74582aca65f710a57e3d 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 61 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_09865 875d0fa72a6c74582aca65f710a57e3d 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 6.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09865 875d0fa72a6c74582aca65f710a57e3d 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09865 875d0fa72a6c74582aca65f710a57e3d 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.3E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09865 875d0fa72a6c74582aca65f710a57e3d 200 SUPERFAMILY SSF46689 5 89 3.95E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_05575 cb009cfd704858d6d7d3030792a32c30 363 SUPERFAMILY SSF48371 37 234 8.64E-33 T 14-10-2018 IPR016024 Armadillo-type fold A4R43_05575 cb009cfd704858d6d7d3030792a32c30 363 Gene3D G3DSA:1.25.40.290 116 232 6.4E-31 T 14-10-2018 A4R43_06240 5ee2034922512c90864fd581a2168750 418 Pfam PF00999 Sodium/hydrogen exchanger family 10 403 7.0E-31 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 Gene3D G3DSA:1.10.10.10 17 83 3.9E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 Gene3D G3DSA:3.40.1410.10 84 248 3.3E-45 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 SUPERFAMILY SSF64288 70 246 6.6E-48 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 SMART SM00866 102 239 2.5E-36 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 Pfam PF07702 UTRA domain 103 239 7.8E-33 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 6.7E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 6.7E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 SUPERFAMILY SSF46785 16 91 2.53E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 SMART SM00345 24 82 7.8E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04615 524f8bc7b301ce1484ac014e2a6fb1cb 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 81 8.5E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_41700 f4bc8b736ee89fe3003e01afff01bf8d 567 SUPERFAMILY SSF90123 16 328 4.97E-51 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_41700 f4bc8b736ee89fe3003e01afff01bf8d 567 Gene3D G3DSA:3.40.50.300 350 561 8.7E-45 T 14-10-2018 A4R43_41700 f4bc8b736ee89fe3003e01afff01bf8d 567 SUPERFAMILY SSF52540 370 557 1.55E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41700 f4bc8b736ee89fe3003e01afff01bf8d 567 ProSitePatterns PS00211 ABC transporters family signature. 462 476 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_41700 f4bc8b736ee89fe3003e01afff01bf8d 567 Gene3D G3DSA:1.20.1560.10 5 330 5.7E-47 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_41700 f4bc8b736ee89fe3003e01afff01bf8d 567 Pfam PF00664 ABC transporter transmembrane region 44 296 1.4E-20 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_41700 f4bc8b736ee89fe3003e01afff01bf8d 567 Pfam PF00005 ABC transporter 371 489 1.9E-9 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 Gene3D G3DSA:1.10.10.10 1 55 2.0E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 Gene3D G3DSA:1.10.10.10 174 226 8.2E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 Pfam PF01037 Lrp/AsnC ligand binding domain 256 313 2.1E-8 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 SUPERFAMILY SSF46785 5 55 9.89E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 SUPERFAMILY SSF54909 236 321 2.28E-9 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 Pfam PF13404 AsnC-type helix-turn-helix domain 7 46 3.9E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 Pfam PF13404 AsnC-type helix-turn-helix domain 177 218 7.6E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 SMART SM00344 6 110 8.2E-5 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 SMART SM00344 177 283 2.7E-5 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 SUPERFAMILY SSF46785 174 238 2.43E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.5E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.5E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.5E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_22610 1edc68ddf5f1bafea1b4b303f58a8c5a 331 Gene3D G3DSA:3.30.70.920 229 322 1.3E-12 T 14-10-2018 A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 Gene3D G3DSA:3.10.450.50 304 429 3.7E-14 T 14-10-2018 A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 Pfam PF08281 Sigma-70, region 4 241 291 4.5E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 Gene3D G3DSA:1.10.10.10 219 297 1.4E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 111 432 2.5E-117 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 SUPERFAMILY SSF88659 237 295 2.24E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 SUPERFAMILY SSF88946 110 195 5.02E-30 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 Pfam PF04542 Sigma-70 region 2 119 185 1.2E-23 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 SUPERFAMILY SSF54427 310 423 6.53E-12 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 140 171 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 114 295 3.0E-28 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 Gene3D G3DSA:1.10.1740.10 93 201 1.5E-28 T 14-10-2018 A4R43_11940 7e65c812990beeb24d43732d30c2dcfe 437 Pfam PF12680 SnoaL-like domain 317 419 6.9E-8 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_10775 1f81d08596b53cf55dc2f8ff840569c6 284 Hamap MF_02113_B Proteasome subunit beta [prcB]. 8 282 48.459 T 14-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 A4R43_10775 1f81d08596b53cf55dc2f8ff840569c6 284 Gene3D G3DSA:3.60.20.10 55 283 8.6E-82 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_10775 1f81d08596b53cf55dc2f8ff840569c6 284 SUPERFAMILY SSF56235 51 267 5.5E-50 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_10775 1f81d08596b53cf55dc2f8ff840569c6 284 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 51 277 5.5E-105 T 14-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 A4R43_10775 1f81d08596b53cf55dc2f8ff840569c6 284 Pfam PF00227 Proteasome subunit 52 237 1.1E-28 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A4R43_40245 c16e698e0ee2851108af27ba8e992b69 413 Gene3D G3DSA:1.10.1740.10 5 74 2.7E-6 T 14-10-2018 A4R43_40245 c16e698e0ee2851108af27ba8e992b69 413 SUPERFAMILY SSF88659 107 167 1.78E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_40245 c16e698e0ee2851108af27ba8e992b69 413 Pfam PF09976 Tetratricopeptide repeat-like domain 330 413 8.3E-6 T 14-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 A4R43_40245 c16e698e0ee2851108af27ba8e992b69 413 Gene3D G3DSA:1.25.40.10 358 413 1.8E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_40245 c16e698e0ee2851108af27ba8e992b69 413 Gene3D G3DSA:1.10.10.10 117 169 1.1E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40245 c16e698e0ee2851108af27ba8e992b69 413 Pfam PF04542 Sigma-70 region 2 14 76 4.1E-7 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_40245 c16e698e0ee2851108af27ba8e992b69 413 Pfam PF08281 Sigma-70, region 4 117 165 6.2E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_40245 c16e698e0ee2851108af27ba8e992b69 413 SUPERFAMILY SSF88946 8 91 8.63E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_26535 3334fda2db034f6e753e30cf6bd53738 842 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 23 250 2.9E-34 T 14-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 A4R43_26535 3334fda2db034f6e753e30cf6bd53738 842 Gene3D G3DSA:3.30.70.1020 104 180 2.7E-47 T 14-10-2018 A4R43_26535 3334fda2db034f6e753e30cf6bd53738 842 Pfam PF02358 Trehalose-phosphatase 27 216 4.0E-30 T 14-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 A4R43_26535 3334fda2db034f6e753e30cf6bd53738 842 SUPERFAMILY SSF48208 460 839 2.65E-88 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_26535 3334fda2db034f6e753e30cf6bd53738 842 Gene3D G3DSA:3.40.50.1000 25 236 2.7E-47 T 14-10-2018 IPR023214 HAD superfamily A4R43_26535 3334fda2db034f6e753e30cf6bd53738 842 Gene3D G3DSA:1.50.10.10 475 842 9.7E-75 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_26535 3334fda2db034f6e753e30cf6bd53738 842 Pfam PF00723 Glycosyl hydrolases family 15 478 837 5.9E-32 T 14-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 A4R43_26535 3334fda2db034f6e753e30cf6bd53738 842 SUPERFAMILY SSF56784 24 250 2.29E-33 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_30620 c738ba35db14893f9824bee371a81df8 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 6.3E-59 T 14-10-2018 A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 8.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30620 c738ba35db14893f9824bee371a81df8 245 SUPERFAMILY SSF51735 1 243 1.11E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_30620 c738ba35db14893f9824bee371a81df8 245 Gene3D G3DSA:3.40.50.720 1 244 1.3E-82 T 14-10-2018 A4R43_30620 c738ba35db14893f9824bee371a81df8 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 1.1E-4 T 14-10-2018 A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30620 c738ba35db14893f9824bee371a81df8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03395 b76efd21ff38f190599f6d6e2ca1deb2 153 Pfam PF05103 DivIVA protein 2 126 8.3E-8 T 14-10-2018 IPR007793 DivIVA family A4R43_28815 c3a261c85d58ef7a64ccbd901df8bb13 292 Gene3D G3DSA:3.10.180.10 50 175 9.0E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_28815 c3a261c85d58ef7a64ccbd901df8bb13 292 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 246 288 3.3E-4 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_28815 c3a261c85d58ef7a64ccbd901df8bb13 292 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 57 166 2.0E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_28815 c3a261c85d58ef7a64ccbd901df8bb13 292 Gene3D G3DSA:3.10.180.10 176 292 3.6E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_28815 c3a261c85d58ef7a64ccbd901df8bb13 292 SUPERFAMILY SSF54593 52 183 5.91E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_28815 c3a261c85d58ef7a64ccbd901df8bb13 292 SUPERFAMILY SSF54593 189 291 1.05E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 Pfam PF00701 Dihydrodipicolinate synthetase family 11 293 2.0E-82 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 9 298 53.032 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 SUPERFAMILY SSF51569 10 297 8.79E-95 T 14-10-2018 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 Gene3D G3DSA:3.20.20.70 8 300 1.3E-100 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 79 97 6.0E-23 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 6.0E-23 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 111 127 6.0E-23 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 43 64 6.0E-23 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 173 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 PIRSF PIRSF001365 6 305 2.5E-84 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 SMART SM01130 9 299 3.0E-119 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_13540 c0984a5e764a33f6ccc150819de8e618 309 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 13 297 7.4E-82 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41305 e47f47f83d0231b83aa46c980c04b9ba 153 Pfam PF02464 Competence-damaged protein 3 150 8.4E-48 T 14-10-2018 IPR008136 CinA, C-terminal A4R43_41305 e47f47f83d0231b83aa46c980c04b9ba 153 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 7 148 6.5E-33 T 14-10-2018 IPR008136 CinA, C-terminal A4R43_41305 e47f47f83d0231b83aa46c980c04b9ba 153 SUPERFAMILY SSF142433 3 150 1.83E-43 T 14-10-2018 IPR036653 CinA-like, C-terminal A4R43_41305 e47f47f83d0231b83aa46c980c04b9ba 153 Gene3D G3DSA:3.90.950.20 1 153 4.5E-52 T 14-10-2018 IPR036653 CinA-like, C-terminal A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 SUPERFAMILY SSF53748 4 402 1.0E-138 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 177 199 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 147 169 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 112 127 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 200 219 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 322 347 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 355 366 8.4E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 Gene3D G3DSA:3.40.50.1260 14 401 5.3E-140 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 Pfam PF00162 Phosphoglycerate kinase 14 393 2.2E-141 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 403 40.602 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 18 28 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 PIRSF PIRSF000724 1 403 6.1E-131 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04920 49b43d8fae14a98c1da8be2e8281d5aa 403 Gene3D G3DSA:3.40.50.1260 179 393 5.3E-140 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_39535 5a840ff568d1b046e94f0f8f4597cc2e 659 Pfam PF03176 MMPL family 456 657 4.1E-32 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_39535 5a840ff568d1b046e94f0f8f4597cc2e 659 Pfam PF03176 MMPL family 68 354 1.1E-61 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_39535 5a840ff568d1b046e94f0f8f4597cc2e 659 SUPERFAMILY SSF82866 101 326 1.7E-32 T 14-10-2018 A4R43_39535 5a840ff568d1b046e94f0f8f4597cc2e 659 SUPERFAMILY SSF82866 446 656 5.75E-22 T 14-10-2018 A4R43_40730 eaa0af1bb499a1e9c5abcee7cc998471 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 8.8E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40730 eaa0af1bb499a1e9c5abcee7cc998471 189 SUPERFAMILY SSF46689 4 78 7.7E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_40730 eaa0af1bb499a1e9c5abcee7cc998471 189 Gene3D G3DSA:1.10.357.10 1 186 3.6E-21 T 14-10-2018 A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 8 231 2.4E-64 T 14-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 Pfam PF00702 haloacid dehalogenase-like hydrolase 8 204 2.6E-6 T 14-10-2018 A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 Gene3D G3DSA:1.10.720.60 21 104 1.3E-62 T 14-10-2018 A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 Gene3D G3DSA:3.40.50.1000 10 231 1.3E-62 T 14-10-2018 IPR023214 HAD superfamily A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 SUPERFAMILY SSF56784 8 234 9.75E-55 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 199 212 8.8E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 8.8E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 192 8.8E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 120 133 8.8E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_35065 5e9dd932732979f7b87afc92e9197b44 239 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 6 234 37.816 T 14-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 A4R43_07990 44266c6c970378477d43edd34e6d2b15 230 Pfam PF01965 DJ-1/PfpI family 29 226 3.1E-14 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_07990 44266c6c970378477d43edd34e6d2b15 230 SUPERFAMILY SSF52317 3 229 3.4E-60 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_07990 44266c6c970378477d43edd34e6d2b15 230 Gene3D G3DSA:3.40.50.880 1 230 5.6E-72 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_35405 f32b530039d4b90107569889aff45e24 372 Gene3D G3DSA:1.10.260.150 46 346 7.8E-67 T 14-10-2018 A4R43_35405 f32b530039d4b90107569889aff45e24 372 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 92 261 4.6E-40 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_35405 f32b530039d4b90107569889aff45e24 372 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 92 262 2.0E-34 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_31125 c3d2d5d873591c45677180080dd709f5 637 Gene3D G3DSA:1.20.1560.10 58 368 3.2E-27 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_31125 c3d2d5d873591c45677180080dd709f5 637 SMART SM00382 414 605 2.9E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_31125 c3d2d5d873591c45677180080dd709f5 637 Gene3D G3DSA:3.40.50.300 380 632 7.3E-86 T 14-10-2018 A4R43_31125 c3d2d5d873591c45677180080dd709f5 637 Pfam PF00005 ABC transporter 405 559 1.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_31125 c3d2d5d873591c45677180080dd709f5 637 SUPERFAMILY SSF52540 379 629 2.15E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31125 c3d2d5d873591c45677180080dd709f5 637 Pfam PF00664 ABC transporter transmembrane region 67 340 1.5E-9 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_31125 c3d2d5d873591c45677180080dd709f5 637 ProSitePatterns PS00211 ABC transporters family signature. 531 545 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_31125 c3d2d5d873591c45677180080dd709f5 637 SUPERFAMILY SSF90123 50 351 1.1E-37 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_38860 257b83dc80fbd8594561bb1143fd4c2e 166 SMART SM00507 69 118 5.3E-13 T 14-10-2018 IPR003615 HNH nuclease A4R43_38860 257b83dc80fbd8594561bb1143fd4c2e 166 Gene3D G3DSA:3.30.40.60 62 144 1.6E-19 T 14-10-2018 A4R43_38860 257b83dc80fbd8594561bb1143fd4c2e 166 Pfam PF14279 HNH endonuclease 82 125 4.0E-12 T 14-10-2018 IPR029471 HNH endonuclease 5 A4R43_07865 3c8e04c277a7bb58384fae74328aada7 266 SUPERFAMILY SSF52096 4 264 9.81E-83 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_07865 3c8e04c277a7bb58384fae74328aada7 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_07865 3c8e04c277a7bb58384fae74328aada7 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 264 4.8E-63 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_07865 3c8e04c277a7bb58384fae74328aada7 266 Gene3D G3DSA:1.10.12.10 209 266 1.7E-19 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_07865 3c8e04c277a7bb58384fae74328aada7 266 Gene3D G3DSA:3.90.226.10 1 206 5.7E-66 T 14-10-2018 A4R43_09905 4dd135bf73c23262934e2135cbdb9079 331 Gene3D G3DSA:3.40.50.1980 27 167 4.8E-19 T 14-10-2018 A4R43_09905 4dd135bf73c23262934e2135cbdb9079 331 Pfam PF01497 Periplasmic binding protein 64 300 7.2E-12 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_09905 4dd135bf73c23262934e2135cbdb9079 331 Gene3D G3DSA:3.40.50.1980 173 330 8.1E-14 T 14-10-2018 A4R43_09905 4dd135bf73c23262934e2135cbdb9079 331 SUPERFAMILY SSF53807 40 314 1.81E-29 T 14-10-2018 A4R43_14165 dccb9ea36eff56bc995dc61955bc2c87 205 Gene3D G3DSA:1.10.10.10 107 200 1.9E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14165 dccb9ea36eff56bc995dc61955bc2c87 205 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 31 192 2.6E-30 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A4R43_14165 dccb9ea36eff56bc995dc61955bc2c87 205 SUPERFAMILY SSF46785 31 105 4.28E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14165 dccb9ea36eff56bc995dc61955bc2c87 205 SUPERFAMILY SSF46785 109 182 1.43E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14165 dccb9ea36eff56bc995dc61955bc2c87 205 PIRSF PIRSF019345 18 204 3.2E-56 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A4R43_14165 dccb9ea36eff56bc995dc61955bc2c87 205 Pfam PF04079 Segregation and condensation complex subunit ScpB 33 191 4.0E-50 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A4R43_14165 dccb9ea36eff56bc995dc61955bc2c87 205 Gene3D G3DSA:1.10.10.10 17 106 3.8E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27395 0072dfe3f86a2f15a5299dc38963f519 333 Gene3D G3DSA:3.40.50.300 1 325 1.0E-89 T 14-10-2018 A4R43_27395 0072dfe3f86a2f15a5299dc38963f519 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 8.7E-21 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_27395 0072dfe3f86a2f15a5299dc38963f519 333 SMART SM00382 33 231 3.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_27395 0072dfe3f86a2f15a5299dc38963f519 333 SUPERFAMILY SSF52540 33 306 2.07E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27395 0072dfe3f86a2f15a5299dc38963f519 333 Pfam PF00005 ABC transporter 25 182 6.9E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_27395 0072dfe3f86a2f15a5299dc38963f519 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 1.7E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_27395 0072dfe3f86a2f15a5299dc38963f519 333 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 273 284 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 350 361 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 90 101 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 192 214 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 154 169 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 137 153 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 341 350 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 292 319 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00359 B-class P450 signature 320 335 4.5E-65 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 SUPERFAMILY SSF48264 23 399 4.45E-104 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 Gene3D G3DSA:1.10.630.10 4 401 7.9E-134 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 Pfam PF00067 Cytochrome P450 43 370 1.5E-31 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00385 P450 superfamily signature 350 361 1.4E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00385 P450 superfamily signature 341 350 1.4E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00385 P450 superfamily signature 238 255 1.4E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_19670 1c6863650b5564d4d9eb46897c2650c8 401 PRINTS PR00385 P450 superfamily signature 273 284 1.4E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_14920 c4fbc5211ada0364d082c1dee746eb26 390 Pfam PF01555 DNA methylase 30 374 4.7E-53 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4R43_14920 c4fbc5211ada0364d082c1dee746eb26 390 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 34 39 - T 14-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 A4R43_14920 c4fbc5211ada0364d082c1dee746eb26 390 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 318 335 2.6E-30 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_14920 c4fbc5211ada0364d082c1dee746eb26 390 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 360 380 2.6E-30 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_14920 c4fbc5211ada0364d082c1dee746eb26 390 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 29 43 2.6E-30 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_14920 c4fbc5211ada0364d082c1dee746eb26 390 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 100 120 2.6E-30 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_14920 c4fbc5211ada0364d082c1dee746eb26 390 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 337 355 2.6E-30 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_14920 c4fbc5211ada0364d082c1dee746eb26 390 SUPERFAMILY SSF53335 4 380 7.8E-60 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_36050 47ad67c8c2de117e8be6eecfc3994ace 270 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 247 2.1E-46 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A4R43_36050 47ad67c8c2de117e8be6eecfc3994ace 270 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 249 3.0E-67 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A4R43_36050 47ad67c8c2de117e8be6eecfc3994ace 270 SUPERFAMILY SSF102705 3 268 7.85E-77 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily A4R43_36050 47ad67c8c2de117e8be6eecfc3994ace 270 Gene3D G3DSA:3.40.1390.30 102 230 4.2E-65 T 14-10-2018 A4R43_36050 47ad67c8c2de117e8be6eecfc3994ace 270 Gene3D G3DSA:3.40.1390.30 8 240 4.2E-65 T 14-10-2018 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 PRINTS PR01270 Histone deacetylase superfamily signature 125 148 5.5E-18 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 PRINTS PR01270 Histone deacetylase superfamily signature 158 173 5.5E-18 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 PRINTS PR01270 Histone deacetylase superfamily signature 244 254 5.5E-18 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 Gene3D G3DSA:3.40.800.20 4 334 2.4E-105 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 SUPERFAMILY SSF52768 4 331 4.12E-106 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 102 115 1.4E-10 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 269 285 1.4E-10 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 81 95 1.4E-10 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 1.4E-10 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A4R43_16675 fcce04bedee46d635a601b3dd4d54848 390 Pfam PF00850 Histone deacetylase domain 21 314 6.3E-78 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4R43_17430 6c846008612c6b35984baefc7cacec5d 338 Pfam PF02607 B12 binding domain 10 81 7.7E-10 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_17430 6c846008612c6b35984baefc7cacec5d 338 Gene3D G3DSA:1.10.1240.10 5 85 1.2E-7 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_17430 6c846008612c6b35984baefc7cacec5d 338 Pfam PF02310 B12 binding domain 95 203 2.6E-17 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_17430 6c846008612c6b35984baefc7cacec5d 338 SUPERFAMILY SSF52242 92 213 9.94E-21 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_17430 6c846008612c6b35984baefc7cacec5d 338 Gene3D G3DSA:3.40.50.280 91 211 2.3E-22 T 14-10-2018 A4R43_19395 a5598ede0727636198438fe9e64300db 157 Gene3D G3DSA:1.10.10.10 8 156 6.4E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19395 a5598ede0727636198438fe9e64300db 157 SUPERFAMILY SSF46785 14 147 5.27E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19395 a5598ede0727636198438fe9e64300db 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 4.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_19395 a5598ede0727636198438fe9e64300db 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 4.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_19395 a5598ede0727636198438fe9e64300db 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 4.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_19395 a5598ede0727636198438fe9e64300db 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 4.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_19395 a5598ede0727636198438fe9e64300db 157 SMART SM00347 32 132 1.6E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_19395 a5598ede0727636198438fe9e64300db 157 Pfam PF01047 MarR family 40 95 5.7E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_19395 a5598ede0727636198438fe9e64300db 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 185 416 1.3E-45 T 14-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 SUPERFAMILY SSF51735 1 158 3.8E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 Gene3D G3DSA:3.40.50.720 1 157 4.3E-50 T 14-10-2018 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 SUPERFAMILY SSF56327 159 435 4.63E-65 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 Pfam PF02056 Family 4 glycosyl hydrolase 3 175 9.8E-45 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 Gene3D G3DSA:3.90.110.10 159 438 7.3E-75 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 130 160 - T 14-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 130 147 3.7E-40 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 155 166 3.7E-40 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 181 193 3.7E-40 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 66 82 3.7E-40 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 101 121 3.7E-40 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_07395 2d7482365fa3e4cded2c55c90ccb9536 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 87 100 3.7E-40 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_29325 8a318536737a7dca12bf3ace207e6124 123 Gene3D G3DSA:3.10.450.50 3 122 5.8E-12 T 14-10-2018 A4R43_29325 8a318536737a7dca12bf3ace207e6124 123 SUPERFAMILY SSF54427 7 122 1.46E-14 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_29325 8a318536737a7dca12bf3ace207e6124 123 Pfam PF14534 Domain of unknown function (DUF4440) 12 115 6.6E-9 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 A4R43_17480 1461c433dcd76bbdddd40d919ca5efa0 365 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 180 270 6.8E-14 T 14-10-2018 IPR021368 Type VII secretion system protein EccE A4R43_19945 501a51b46cb2062d025d775ca7958629 535 SUPERFAMILY SSF110921 411 526 5.75E-26 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_19945 501a51b46cb2062d025d775ca7958629 535 SUPERFAMILY SSF51569 11 304 9.71E-71 T 14-10-2018 A4R43_19945 501a51b46cb2062d025d775ca7958629 535 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 16 531 3.5E-174 T 14-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 A4R43_19945 501a51b46cb2062d025d775ca7958629 535 Pfam PF00682 HMGL-like 16 280 1.1E-41 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4R43_19945 501a51b46cb2062d025d775ca7958629 535 SMART SM00917 386 530 8.9E-39 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_19945 501a51b46cb2062d025d775ca7958629 535 Gene3D G3DSA:3.30.160.270 409 530 2.2E-8 T 14-10-2018 A4R43_19945 501a51b46cb2062d025d775ca7958629 535 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 22 38 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_19945 501a51b46cb2062d025d775ca7958629 535 Gene3D G3DSA:3.20.20.70 15 337 1.7E-94 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_19945 501a51b46cb2062d025d775ca7958629 535 Pfam PF08502 LeuA allosteric (dimerisation) domain 386 527 9.0E-27 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 SUPERFAMILY SSF54427 173 283 1.81E-12 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 Gene3D G3DSA:1.10.1740.10 2 101 2.4E-10 T 14-10-2018 A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 Pfam PF04542 Sigma-70 region 2 14 77 1.3E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 Gene3D G3DSA:3.10.450.50 170 286 3.3E-7 T 14-10-2018 A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 Gene3D G3DSA:1.10.10.10 108 163 2.8E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 Pfam PF08281 Sigma-70, region 4 109 159 3.0E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 SUPERFAMILY SSF88946 7 86 4.32E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 SUPERFAMILY SSF88659 102 161 7.85E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_13305 c9c80669ef6ee93b1ebe2d769450f8d6 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 161 2.9E-17 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_25005 313d2998e110298cd42a8e919c04cb05 219 Gene3D G3DSA:3.90.550.10 2 219 5.8E-40 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_25005 313d2998e110298cd42a8e919c04cb05 219 SUPERFAMILY SSF53448 5 199 1.9E-34 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_25005 313d2998e110298cd42a8e919c04cb05 219 Pfam PF00535 Glycosyl transferase family 2 7 125 1.9E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_04760 bbd5b0e38cba8bcd52b9ad8899567f7f 414 Gene3D G3DSA:3.40.50.10300 186 414 1.1E-82 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4R43_04760 bbd5b0e38cba8bcd52b9ad8899567f7f 414 Pfam PF02441 Flavoprotein 10 175 2.8E-35 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4R43_04760 bbd5b0e38cba8bcd52b9ad8899567f7f 414 SUPERFAMILY SSF102645 186 408 4.32E-67 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4R43_04760 bbd5b0e38cba8bcd52b9ad8899567f7f 414 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 191 380 8.8E-69 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4R43_04760 bbd5b0e38cba8bcd52b9ad8899567f7f 414 SUPERFAMILY SSF52507 7 177 2.22E-52 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A4R43_04760 bbd5b0e38cba8bcd52b9ad8899567f7f 414 Gene3D G3DSA:3.40.50.1950 6 185 2.8E-47 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A4R43_04760 bbd5b0e38cba8bcd52b9ad8899567f7f 414 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 10 405 1.8E-111 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A4R43_32855 6f8409bb175fb34d3026ec2366c651a2 328 Gene3D G3DSA:3.40.50.1000 80 292 2.5E-59 T 14-10-2018 IPR023214 HAD superfamily A4R43_32855 6f8409bb175fb34d3026ec2366c651a2 328 SUPERFAMILY SSF56784 79 297 2.44E-27 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_32855 6f8409bb175fb34d3026ec2366c651a2 328 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 79 269 2.0E-17 T 14-10-2018 A4R43_32855 6f8409bb175fb34d3026ec2366c651a2 328 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 79 280 4.2E-54 T 14-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like A4R43_32855 6f8409bb175fb34d3026ec2366c651a2 328 Pfam PF12710 haloacid dehalogenase-like hydrolase 80 266 1.1E-25 T 14-10-2018 A4R43_32855 6f8409bb175fb34d3026ec2366c651a2 328 Gene3D G3DSA:1.20.1440.100 91 167 2.5E-59 T 14-10-2018 A4R43_17255 d74a98683cc9fe28b46a43b7c46182f4 109 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 101 8.1E-35 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4R43_17255 d74a98683cc9fe28b46a43b7c46182f4 109 SUPERFAMILY SSF141734 5 104 3.27E-46 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A4R43_17255 d74a98683cc9fe28b46a43b7c46182f4 109 Gene3D G3DSA:3.10.20.400 1 93 1.3E-40 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A4R43_17255 d74a98683cc9fe28b46a43b7c46182f4 109 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 106 30.364 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4R43_17255 d74a98683cc9fe28b46a43b7c46182f4 109 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 52 101 3.0E-16 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4R43_15835 f6a2372ca882689ca8da6f514ae62741 512 Pfam PF05175 Methyltransferase small domain 156 245 4.7E-16 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A4R43_15835 f6a2372ca882689ca8da6f514ae62741 512 Gene3D G3DSA:3.40.50.150 147 302 9.3E-27 T 14-10-2018 A4R43_15835 f6a2372ca882689ca8da6f514ae62741 512 SUPERFAMILY SSF53335 161 325 7.84E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_15835 f6a2372ca882689ca8da6f514ae62741 512 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 236 242 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4R43_04620 d3337efd6f9d611ab6d81b8dcfee5539 78 SUPERFAMILY SSF55604 7 77 3.92E-21 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A4R43_04620 d3337efd6f9d611ab6d81b8dcfee5539 78 Pfam PF00367 phosphotransferase system, EIIB 8 40 1.0E-12 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A4R43_04620 d3337efd6f9d611ab6d81b8dcfee5539 78 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 3 64 1.1E-16 T 14-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A4R43_04620 d3337efd6f9d611ab6d81b8dcfee5539 78 Gene3D G3DSA:3.30.1360.60 6 78 9.3E-27 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A4R43_04150 ff7981e1ad69b769cda61dcc266df363 520 Pfam PF13727 CoA-binding domain 138 259 8.4E-8 T 14-10-2018 A4R43_04150 ff7981e1ad69b769cda61dcc266df363 520 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 69 520 3.1E-124 T 14-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase A4R43_04150 ff7981e1ad69b769cda61dcc266df363 520 Pfam PF02397 Bacterial sugar transferase 327 514 1.2E-67 T 14-10-2018 IPR003362 Bacterial sugar transferase A4R43_31350 9b3e2dd1e27e7405a77ddd79f29d4448 251 Gene3D G3DSA:3.60.15.10 2 250 2.0E-67 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_31350 9b3e2dd1e27e7405a77ddd79f29d4448 251 SUPERFAMILY SSF56281 6 249 3.93E-48 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_31350 9b3e2dd1e27e7405a77ddd79f29d4448 251 Pfam PF12706 Beta-lactamase superfamily domain 33 217 9.4E-26 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_31350 9b3e2dd1e27e7405a77ddd79f29d4448 251 SMART SM00849 22 212 0.0052 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_07175 54022ea24357207cdd06f3d8c1282540 462 Gene3D G3DSA:3.20.20.80 40 371 2.7E-93 T 14-10-2018 A4R43_07175 54022ea24357207cdd06f3d8c1282540 462 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 123 227 3.2E-9 T 14-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A4R43_07175 54022ea24357207cdd06f3d8c1282540 462 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 368 457 8.0E-12 T 14-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A4R43_07175 54022ea24357207cdd06f3d8c1282540 462 SUPERFAMILY SSF51445 39 369 5.62E-44 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_07175 54022ea24357207cdd06f3d8c1282540 462 SUPERFAMILY SSF51011 365 457 4.17E-15 T 14-10-2018 A4R43_07175 54022ea24357207cdd06f3d8c1282540 462 Gene3D G3DSA:2.60.40.1180 35 457 2.7E-93 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta A4R43_28755 0619b77584dbc30b6448d2fb4bcf5172 254 SUPERFAMILY SSF53335 30 194 4.51E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_28755 0619b77584dbc30b6448d2fb4bcf5172 254 Gene3D G3DSA:3.40.50.150 28 195 4.4E-21 T 14-10-2018 A4R43_28755 0619b77584dbc30b6448d2fb4bcf5172 254 Pfam PF13649 Methyltransferase domain 61 152 2.3E-11 T 14-10-2018 A4R43_06665 9467fd678a442b81274e9bce5df1280f 577 SUPERFAMILY SSF90123 6 315 1.44E-71 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_06665 9467fd678a442b81274e9bce5df1280f 577 Gene3D G3DSA:1.20.1560.10 2 316 6.1E-80 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_06665 9467fd678a442b81274e9bce5df1280f 577 Pfam PF00005 ABC transporter 351 498 2.2E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_06665 9467fd678a442b81274e9bce5df1280f 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_06665 9467fd678a442b81274e9bce5df1280f 577 SUPERFAMILY SSF52540 326 571 1.2E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06665 9467fd678a442b81274e9bce5df1280f 577 Pfam PF00664 ABC transporter transmembrane region 20 287 8.3E-43 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_06665 9467fd678a442b81274e9bce5df1280f 577 SMART SM00382 360 546 1.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_06665 9467fd678a442b81274e9bce5df1280f 577 Gene3D G3DSA:3.40.50.300 330 574 7.9E-79 T 14-10-2018 A4R43_26090 e8ceb3fae2f5e9a4d65f1d318f1c6afc 225 Gene3D G3DSA:3.60.160.10 1 225 2.2E-65 T 14-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily A4R43_26090 e8ceb3fae2f5e9a4d65f1d318f1c6afc 225 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 223 5.1E-46 T 14-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A4R43_26090 e8ceb3fae2f5e9a4d65f1d318f1c6afc 225 SUPERFAMILY SSF51219 1 224 1.6E-57 T 14-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A4R43_26090 e8ceb3fae2f5e9a4d65f1d318f1c6afc 225 Pfam PF01987 Mitochondrial biogenesis AIM24 6 209 1.5E-49 T 14-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A4R43_24055 b8189e8cbd4a5626d29e2576b1eba23a 559 Pfam PF00501 AMP-binding enzyme 26 449 4.8E-62 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_24055 b8189e8cbd4a5626d29e2576b1eba23a 559 Gene3D G3DSA:3.30.300.30 444 557 2.6E-25 T 14-10-2018 A4R43_24055 b8189e8cbd4a5626d29e2576b1eba23a 559 SUPERFAMILY SSF56801 6 556 1.02E-90 T 14-10-2018 A4R43_24055 b8189e8cbd4a5626d29e2576b1eba23a 559 Gene3D G3DSA:3.40.50.12780 1 442 3.5E-104 T 14-10-2018 A4R43_35325 610a52d92085a00971c84322bfd0c9f4 417 Pfam PF13556 PucR C-terminal helix-turn-helix domain 350 405 7.0E-18 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_35325 610a52d92085a00971c84322bfd0c9f4 417 Gene3D G3DSA:1.10.10.2840 279 409 3.7E-22 T 14-10-2018 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 PRINTS PR00732 Glycosyl hydrolase family 4 signature 160 171 1.8E-27 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 1.8E-27 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 1.8E-27 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 PRINTS PR00732 Glycosyl hydrolase family 4 signature 186 198 1.8E-27 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 1.8E-27 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 1.8E-27 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 Gene3D G3DSA:3.90.110.10 84 418 1.0E-127 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 191 400 5.9E-44 T 14-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 SUPERFAMILY SSF51735 1 157 4.64E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 Gene3D G3DSA:3.40.50.720 2 163 1.0E-127 T 14-10-2018 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 Pfam PF02056 Family 4 glycosyl hydrolase 2 179 3.5E-38 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4R43_11475 ed2a73cd973b21c227c3ab3073d0a0c4 426 SUPERFAMILY SSF56327 166 422 9.5E-61 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4R43_04740 f18e8a5e066acc5e485027474c990795 275 SUPERFAMILY SSF51366 6 269 5.18E-58 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4R43_04740 f18e8a5e066acc5e485027474c990795 275 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 93 106 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04740 f18e8a5e066acc5e485027474c990795 275 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 4 275 31.84 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04740 f18e8a5e066acc5e485027474c990795 275 Gene3D G3DSA:3.20.20.70 5 275 7.4E-87 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_04740 f18e8a5e066acc5e485027474c990795 275 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 20 264 5.8E-36 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_04740 f18e8a5e066acc5e485027474c990795 275 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 6 265 1.6E-80 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04740 f18e8a5e066acc5e485027474c990795 275 SMART SM00934 19 265 1.1E-31 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_15265 baccdef45019ceb83a297a5b2bdb6b67 289 SUPERFAMILY SSF51679 1 279 2.5E-47 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_15265 baccdef45019ceb83a297a5b2bdb6b67 289 Gene3D G3DSA:3.20.20.30 1 287 1.8E-51 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_15265 baccdef45019ceb83a297a5b2bdb6b67 289 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 18 269 1.1E-75 T 14-10-2018 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted A4R43_15265 baccdef45019ceb83a297a5b2bdb6b67 289 Pfam PF00296 Luciferase-like monooxygenase 15 266 6.7E-38 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_00815 44b6e30ad96fbd5c52489e1b94c3c002 106 Pfam PF01740 STAS domain 9 102 1.8E-13 T 14-10-2018 IPR002645 STAS domain A4R43_00815 44b6e30ad96fbd5c52489e1b94c3c002 106 Gene3D G3DSA:3.30.750.24 2 106 6.3E-26 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_00815 44b6e30ad96fbd5c52489e1b94c3c002 106 SUPERFAMILY SSF52091 5 105 2.55E-20 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_00815 44b6e30ad96fbd5c52489e1b94c3c002 106 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 4 105 2.2E-23 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_04755 4451f55851f2c717bc6070f690df996f 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 15 85 2.5E-27 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_04755 4451f55851f2c717bc6070f690df996f 90 SUPERFAMILY SSF63562 15 86 3.49E-23 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A4R43_04755 4451f55851f2c717bc6070f690df996f 90 Gene3D G3DSA:3.90.940.10 15 90 8.3E-20 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A4R43_04755 4451f55851f2c717bc6070f690df996f 90 Pfam PF01192 RNA polymerase Rpb6 22 84 1.8E-15 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A4R43_04755 4451f55851f2c717bc6070f690df996f 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 15 87 14.304 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_04755 4451f55851f2c717bc6070f690df996f 90 SMART SM01409 22 86 1.9E-14 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A4R43_38555 d277612aa372860e68b36a4c2c975d7a 297 Gene3D G3DSA:3.40.50.720 1 163 1.5E-40 T 14-10-2018 A4R43_38555 d277612aa372860e68b36a4c2c975d7a 297 Gene3D G3DSA:1.10.1040.10 165 293 9.0E-41 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_38555 d277612aa372860e68b36a4c2c975d7a 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 160 1.8E-22 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_38555 d277612aa372860e68b36a4c2c975d7a 297 SUPERFAMILY SSF51735 10 164 4.93E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38555 d277612aa372860e68b36a4c2c975d7a 297 PIRSF PIRSF000103 2 297 8.7E-41 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_18935 c23e83e8f8bacd654ea99f17d3477331 469 SUPERFAMILY SSF51556 50 426 1.36E-32 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_18935 c23e83e8f8bacd654ea99f17d3477331 469 Gene3D G3DSA:2.30.40.10 20 447 2.6E-98 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_18935 c23e83e8f8bacd654ea99f17d3477331 469 SUPERFAMILY SSF51338 18 466 3.02E-12 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_18935 c23e83e8f8bacd654ea99f17d3477331 469 Gene3D G3DSA:3.10.310.70 69 167 2.6E-98 T 14-10-2018 A4R43_18935 c23e83e8f8bacd654ea99f17d3477331 469 Gene3D G3DSA:3.20.20.140 51 431 2.6E-98 T 14-10-2018 A4R43_18935 c23e83e8f8bacd654ea99f17d3477331 469 Pfam PF07969 Amidohydrolase family 39 468 5.7E-58 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 102 4.1E-33 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 Gene3D G3DSA:3.40.30.10 1 105 5.1E-30 T 14-10-2018 A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 SUPERFAMILY SSF52833 4 105 1.07E-32 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 PRINTS PR00421 Thioredoxin family signature 29 38 2.1E-7 T 14-10-2018 A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 PRINTS PR00421 Thioredoxin family signature 69 80 2.1E-7 T 14-10-2018 A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 PRINTS PR00421 Thioredoxin family signature 21 29 2.1E-7 T 14-10-2018 A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 PIRSF PIRSF000077 1 105 3.7E-36 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A4R43_36540 6a15846abd23534c5ad393a4388f73e4 108 Pfam PF00085 Thioredoxin 2 102 1.9E-27 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 A4R43_39555 733c9ebf0d5309fd83ce580c25f5c69f 178 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39555 733c9ebf0d5309fd83ce580c25f5c69f 178 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 51 62 2.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39555 733c9ebf0d5309fd83ce580c25f5c69f 178 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 140 2.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39555 733c9ebf0d5309fd83ce580c25f5c69f 178 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 158 2.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39555 733c9ebf0d5309fd83ce580c25f5c69f 178 Gene3D G3DSA:3.40.50.720 2 175 2.5E-27 T 14-10-2018 A4R43_39555 733c9ebf0d5309fd83ce580c25f5c69f 178 SUPERFAMILY SSF51735 2 164 4.16E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_39555 733c9ebf0d5309fd83ce580c25f5c69f 178 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 48 158 2.1E-11 T 14-10-2018 A4R43_33355 5d2228e86042076e6de342f225faedfd 388 Pfam PF13692 Glycosyl transferases group 1 235 349 7.4E-10 T 14-10-2018 A4R43_33355 5d2228e86042076e6de342f225faedfd 388 SUPERFAMILY SSF53756 11 381 1.15E-25 T 14-10-2018 A4R43_33355 5d2228e86042076e6de342f225faedfd 388 Gene3D G3DSA:3.40.50.2000 208 359 1.0E-19 T 14-10-2018 A4R43_24520 a0415c409873da4928b633cb369f0916 161 Gene3D G3DSA:3.40.50.12280 30 161 2.8E-46 T 14-10-2018 A4R43_24520 a0415c409873da4928b633cb369f0916 161 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 47 158 3.3E-27 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24520 a0415c409873da4928b633cb369f0916 161 SUPERFAMILY SSF56770 35 159 8.37E-49 T 14-10-2018 A4R43_22735 f303dbaf5e7544b0dd263293eb7bf530 230 Gene3D G3DSA:1.20.910.10 1 230 1.3E-62 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_22735 f303dbaf5e7544b0dd263293eb7bf530 230 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 5 226 2.2E-84 T 14-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 A4R43_22735 f303dbaf5e7544b0dd263293eb7bf530 230 Pfam PF03070 TENA/THI-4/PQQC family 14 221 8.9E-44 T 14-10-2018 IPR004305 Thiaminase-2/PQQC A4R43_22735 f303dbaf5e7544b0dd263293eb7bf530 230 SUPERFAMILY SSF48613 2 227 8.4E-59 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_22735 f303dbaf5e7544b0dd263293eb7bf530 230 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 230 96.882 T 14-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 A4R43_17600 98dee5c20cdf03e16d3785b2d3823999 747 SUPERFAMILY SSF53056 516 738 4.06E-54 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A4R43_17600 98dee5c20cdf03e16d3785b2d3823999 747 Pfam PF00916 Sulfate permease family 7 355 1.9E-66 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4R43_17600 98dee5c20cdf03e16d3785b2d3823999 747 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 561 568 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_17600 98dee5c20cdf03e16d3785b2d3823999 747 Pfam PF00484 Carbonic anhydrase 556 724 6.0E-44 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_17600 98dee5c20cdf03e16d3785b2d3823999 747 SMART SM00947 549 729 1.4E-55 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_17600 98dee5c20cdf03e16d3785b2d3823999 747 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 615 635 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_17600 98dee5c20cdf03e16d3785b2d3823999 747 Gene3D G3DSA:3.40.1050.10 515 737 1.8E-57 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A4R43_10995 7cefebd7a6a96f8c06fc47cf0e3e05cf 646 SUPERFAMILY SSF53300 462 635 2.23E-16 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_10995 7cefebd7a6a96f8c06fc47cf0e3e05cf 646 SMART SM00327 460 642 2.0E-12 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_10995 7cefebd7a6a96f8c06fc47cf0e3e05cf 646 Gene3D G3DSA:3.40.50.410 457 640 5.2E-13 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_39065 c3e613c6304b03ae3fff7b30caa7a2d9 305 Gene3D G3DSA:3.30.565.10 181 305 5.8E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39065 c3e613c6304b03ae3fff7b30caa7a2d9 305 SUPERFAMILY SSF55874 214 302 8.75E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39065 c3e613c6304b03ae3fff7b30caa7a2d9 305 Pfam PF13581 Histidine kinase-like ATPase domain 194 300 6.7E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_39065 c3e613c6304b03ae3fff7b30caa7a2d9 305 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 6 150 1.0E-28 T 14-10-2018 IPR025847 MEDS domain A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 Gene3D G3DSA:3.30.420.40 2 255 1.5E-110 T 14-10-2018 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 SUPERFAMILY SSF53067 257 500 6.99E-84 T 14-10-2018 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 254 9.2E-76 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 Gene3D G3DSA:3.30.420.40 256 501 1.5E-94 T 14-10-2018 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 Hamap MF_00186 Glycerol kinase [glpK]. 2 500 55.769 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 PIRSF PIRSF000538 2 501 4.8E-170 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 453 1.9E-65 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 499 7.6E-223 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 SUPERFAMILY SSF53067 4 257 5.3E-90 T 14-10-2018 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_35010 4fc2df755caa181b592a07ea82e03d81 501 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_22415 8cbf6f6400cd3e141637f27cf6e5b908 286 SUPERFAMILY SSF51679 16 236 2.35E-59 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_22415 8cbf6f6400cd3e141637f27cf6e5b908 286 Pfam PF00296 Luciferase-like monooxygenase 20 226 6.9E-56 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_22415 8cbf6f6400cd3e141637f27cf6e5b908 286 Gene3D G3DSA:3.20.20.30 10 282 5.1E-74 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_22415 8cbf6f6400cd3e141637f27cf6e5b908 286 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 36 233 1.8E-59 T 14-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted A4R43_21430 0afbde56457af17d9c70c9132f1bd293 211 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 4 200 29.209 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4R43_21430 0afbde56457af17d9c70c9132f1bd293 211 Gene3D G3DSA:3.30.1380.10 2 202 2.1E-64 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_21430 0afbde56457af17d9c70c9132f1bd293 211 Pfam PF01427 D-ala-D-ala dipeptidase 4 200 1.0E-58 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4R43_21430 0afbde56457af17d9c70c9132f1bd293 211 PIRSF PIRSF026671 1 205 2.5E-57 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4R43_21430 0afbde56457af17d9c70c9132f1bd293 211 SUPERFAMILY SSF55166 1 201 3.92E-68 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_18490 ada545e7dbe5fde12e688812a14c04bc 291 Gene3D G3DSA:2.40.290.10 2 178 6.5E-16 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily A4R43_18490 ada545e7dbe5fde12e688812a14c04bc 291 Pfam PF02735 Ku70/Ku80 beta-barrel domain 14 177 1.6E-31 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A4R43_18490 ada545e7dbe5fde12e688812a14c04bc 291 SMART SM00559 52 180 8.0E-24 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A4R43_18490 ada545e7dbe5fde12e688812a14c04bc 291 PIRSF PIRSF006493 1 289 7.8E-76 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_18490 ada545e7dbe5fde12e688812a14c04bc 291 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 252 6.0E-71 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_18490 ada545e7dbe5fde12e688812a14c04bc 291 SUPERFAMILY SSF100939 1 231 1.22E-46 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily A4R43_18490 ada545e7dbe5fde12e688812a14c04bc 291 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 252 28.931 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_01290 f7265a6280c7e08e881d832e72f50da8 316 SUPERFAMILY SSF56059 129 313 1.36E-14 T 14-10-2018 A4R43_01290 f7265a6280c7e08e881d832e72f50da8 316 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 3 311 3.8E-106 T 14-10-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV-5884 family A4R43_01290 f7265a6280c7e08e881d832e72f50da8 316 Gene3D G3DSA:3.30.470.20 205 313 2.1E-13 T 14-10-2018 A4R43_40440 2ece940efa7ca5e7cc5419c98dea651c 294 Gene3D G3DSA:3.40.50.1820 3 292 5.8E-69 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40440 2ece940efa7ca5e7cc5419c98dea651c 294 SUPERFAMILY SSF53474 8 294 3.4E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40440 2ece940efa7ca5e7cc5419c98dea651c 294 PRINTS PR00412 Epoxide hydrolase signature 113 126 1.4E-7 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_40440 2ece940efa7ca5e7cc5419c98dea651c 294 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.4E-7 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_40440 2ece940efa7ca5e7cc5419c98dea651c 294 PRINTS PR00412 Epoxide hydrolase signature 271 293 1.4E-7 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_40440 2ece940efa7ca5e7cc5419c98dea651c 294 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.4E-7 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_40440 2ece940efa7ca5e7cc5419c98dea651c 294 Pfam PF00561 alpha/beta hydrolase fold 28 156 4.4E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_36215 4e93560e36dc74fd41e3453846272bfc 442 SUPERFAMILY SSF53383 36 436 1.25E-124 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_36215 4e93560e36dc74fd41e3453846272bfc 442 Gene3D G3DSA:3.90.1150.10 16 432 3.4E-165 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_36215 4e93560e36dc74fd41e3453846272bfc 442 Gene3D G3DSA:3.40.640.10 74 335 3.4E-165 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_36215 4e93560e36dc74fd41e3453846272bfc 442 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_36215 4e93560e36dc74fd41e3453846272bfc 442 PIRSF PIRSF000521 138 439 1.6E-32 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_36215 4e93560e36dc74fd41e3453846272bfc 442 PIRSF PIRSF000521 1 146 7.3E-10 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_36215 4e93560e36dc74fd41e3453846272bfc 442 Pfam PF00202 Aminotransferase class-III 36 436 6.2E-126 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_36215 4e93560e36dc74fd41e3453846272bfc 442 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 25 436 1.7E-175 T 14-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 A4R43_00930 02c8411d5c28d307952e3a126d3152d0 333 Gene3D G3DSA:1.10.10.60 212 320 1.6E-21 T 14-10-2018 A4R43_00930 02c8411d5c28d307952e3a126d3152d0 333 SUPERFAMILY SSF46689 268 317 1.05E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00930 02c8411d5c28d307952e3a126d3152d0 333 Gene3D G3DSA:3.40.50.880 2 205 1.2E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_00930 02c8411d5c28d307952e3a126d3152d0 333 SUPERFAMILY SSF46689 215 262 2.01E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00930 02c8411d5c28d307952e3a126d3152d0 333 SMART SM00342 231 314 1.0E-16 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00930 02c8411d5c28d307952e3a126d3152d0 333 SUPERFAMILY SSF52317 5 197 7.94E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_00930 02c8411d5c28d307952e3a126d3152d0 333 Pfam PF12833 Helix-turn-helix domain 237 315 2.0E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00930 02c8411d5c28d307952e3a126d3152d0 333 Pfam PF01965 DJ-1/PfpI family 6 176 1.5E-22 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_10770 fcd6107b72ba52aba1ac1bf15b85eb83 270 Pfam PF00227 Proteasome subunit 25 192 9.1E-31 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A4R43_10770 fcd6107b72ba52aba1ac1bf15b85eb83 270 Gene3D G3DSA:3.60.20.10 1 254 7.5E-65 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_10770 fcd6107b72ba52aba1ac1bf15b85eb83 270 SUPERFAMILY SSF56235 10 240 5.5E-43 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_10770 fcd6107b72ba52aba1ac1bf15b85eb83 270 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 240 1.6E-108 T 14-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 A4R43_10770 fcd6107b72ba52aba1ac1bf15b85eb83 270 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 244 48.493 T 14-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 A4R43_08100 76292c6736982d9607bb81df649bcd88 206 Pfam PF13649 Methyltransferase domain 30 117 5.0E-18 T 14-10-2018 A4R43_08100 76292c6736982d9607bb81df649bcd88 206 SUPERFAMILY SSF53335 15 146 2.32E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_08100 76292c6736982d9607bb81df649bcd88 206 Gene3D G3DSA:3.40.50.150 3 151 1.1E-29 T 14-10-2018 A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 SUPERFAMILY SSF52172 162 228 3.13E-6 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 SMART SM01012 174 229 8.5E-17 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 PIRSF PIRSF036625 2 238 1.3E-62 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 SMART SM00065 24 172 4.1E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 Pfam PF13185 GAF domain 24 162 1.6E-19 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 SUPERFAMILY SSF55781 24 170 4.8E-24 T 14-10-2018 A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 Gene3D G3DSA:1.10.10.10 176 233 2.4E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 Pfam PF03861 ANTAR domain 176 228 1.6E-15 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_21455 43ddfe6a44939ca34321fd04b52f8363 248 Gene3D G3DSA:3.30.450.40 2 173 1.5E-26 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_26875 5106c925ad82173665d5484d49d14638 557 Gene3D G3DSA:1.20.1250.20 275 471 4.7E-23 T 14-10-2018 A4R43_26875 5106c925ad82173665d5484d49d14638 557 SUPERFAMILY SSF103473 17 531 9.02E-66 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_26875 5106c925ad82173665d5484d49d14638 557 Gene3D G3DSA:1.20.1720.10 25 231 2.1E-51 T 14-10-2018 A4R43_26875 5106c925ad82173665d5484d49d14638 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 1.4E-5 T 14-10-2018 A4R43_26875 5106c925ad82173665d5484d49d14638 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 414 433 1.4E-5 T 14-10-2018 A4R43_26875 5106c925ad82173665d5484d49d14638 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 1.4E-5 T 14-10-2018 A4R43_26875 5106c925ad82173665d5484d49d14638 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.4E-5 T 14-10-2018 A4R43_26875 5106c925ad82173665d5484d49d14638 557 Pfam PF07690 Major Facilitator Superfamily 28 426 2.8E-54 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_26875 5106c925ad82173665d5484d49d14638 557 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 527 2.0E-74 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4R43_19500 53d00d4adf095e450eb4466c9a9721be 225 SUPERFAMILY SSF52141 9 223 1.18E-74 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_19500 53d00d4adf095e450eb4466c9a9721be 225 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 14 216 5.0E-56 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_19500 53d00d4adf095e450eb4466c9a9721be 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 34.086 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_19500 53d00d4adf095e450eb4466c9a9721be 225 SMART SM00987 53 212 3.0E-32 T 14-10-2018 A4R43_19500 53d00d4adf095e450eb4466c9a9721be 225 Pfam PF03167 Uracil DNA glycosylase superfamily 56 211 2.9E-18 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_19500 53d00d4adf095e450eb4466c9a9721be 225 SMART SM00986 53 212 3.0E-32 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_19500 53d00d4adf095e450eb4466c9a9721be 225 Gene3D G3DSA:3.40.470.10 1 225 7.9E-87 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_19500 53d00d4adf095e450eb4466c9a9721be 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 14-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_04850 b0c3e436eb77bb88a2c7de1db8983f65 285 Pfam PF03668 P-loop ATPase protein family 1 285 3.6E-109 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 A4R43_04850 b0c3e436eb77bb88a2c7de1db8983f65 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 284 41.056 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 A4R43_04850 b0c3e436eb77bb88a2c7de1db8983f65 285 PIRSF PIRSF005052 1 285 1.5E-111 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 A4R43_04850 b0c3e436eb77bb88a2c7de1db8983f65 285 SUPERFAMILY SSF52540 3 154 2.44E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37275 2377693fc9ea1b28dfd3d0458eb60e72 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 88 8.1E-9 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_37275 2377693fc9ea1b28dfd3d0458eb60e72 393 SUPERFAMILY SSF47203 234 371 5.65E-6 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_37275 2377693fc9ea1b28dfd3d0458eb60e72 393 Gene3D G3DSA:1.10.540.10 3 113 8.3E-31 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_37275 2377693fc9ea1b28dfd3d0458eb60e72 393 SUPERFAMILY SSF56645 13 207 2.49E-34 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_37275 2377693fc9ea1b28dfd3d0458eb60e72 393 Gene3D G3DSA:1.20.140.10 212 392 4.6E-29 T 14-10-2018 A4R43_37275 2377693fc9ea1b28dfd3d0458eb60e72 393 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 243 371 4.1E-23 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4R43_37275 2377693fc9ea1b28dfd3d0458eb60e72 393 PIRSF PIRSF016578 1 393 1.1E-122 T 14-10-2018 A4R43_37275 2377693fc9ea1b28dfd3d0458eb60e72 393 Gene3D G3DSA:2.40.110.10 115 207 3.7E-27 T 14-10-2018 A4R43_19685 84aa96180db9068d4d1c6dc68ac00481 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 1.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19685 84aa96180db9068d4d1c6dc68ac00481 187 SUPERFAMILY SSF46689 10 76 3.18E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19685 84aa96180db9068d4d1c6dc68ac00481 187 Gene3D G3DSA:1.10.357.10 6 186 4.6E-20 T 14-10-2018 A4R43_40205 73a3ebb6ca9c3440ec0da9901a03bf05 210 Gene3D G3DSA:1.10.357.10 3 206 3.6E-31 T 14-10-2018 A4R43_40205 73a3ebb6ca9c3440ec0da9901a03bf05 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 59 1.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40205 73a3ebb6ca9c3440ec0da9901a03bf05 210 SUPERFAMILY SSF46689 3 77 3.95E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_12805 1cc6b13818957eeebc2745958d150140 518 Gene3D G3DSA:2.60.40.650 409 517 5.0E-22 T 14-10-2018 A4R43_12805 1cc6b13818957eeebc2745958d150140 518 Pfam PF00174 Oxidoreductase molybdopterin binding domain 244 391 3.0E-33 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4R43_12805 1cc6b13818957eeebc2745958d150140 518 Gene3D G3DSA:3.90.420.10 206 407 1.4E-44 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A4R43_12805 1cc6b13818957eeebc2745958d150140 518 SUPERFAMILY SSF56524 227 417 1.26E-51 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A4R43_12805 1cc6b13818957eeebc2745958d150140 518 SUPERFAMILY SSF81296 408 515 1.33E-21 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_38390 0c550ac415faca095753bab332eeb3b9 149 Gene3D G3DSA:1.10.10.10 2 148 3.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38390 0c550ac415faca095753bab332eeb3b9 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 3.2E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38390 0c550ac415faca095753bab332eeb3b9 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 3.2E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38390 0c550ac415faca095753bab332eeb3b9 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 3.2E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38390 0c550ac415faca095753bab332eeb3b9 149 Pfam PF01047 MarR family 39 98 1.4E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38390 0c550ac415faca095753bab332eeb3b9 149 SMART SM00347 32 134 1.7E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38390 0c550ac415faca095753bab332eeb3b9 149 SUPERFAMILY SSF46785 11 145 1.09E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 Gene3D G3DSA:3.30.70.270 275 454 1.8E-40 T 14-10-2018 A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 SUPERFAMILY SSF55073 286 445 3.4E-32 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 Gene3D G3DSA:3.30.450.20 142 268 1.3E-14 T 14-10-2018 A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 154 276 4.2E-12 T 14-10-2018 IPR000014 PAS domain A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 SUPERFAMILY SSF141868 462 688 1.96E-28 T 14-10-2018 IPR035919 EAL domain superfamily A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 SMART SM00267 270 443 2.5E-38 T 14-10-2018 IPR000160 GGDEF domain A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 Pfam PF00990 Diguanylate cyclase, GGDEF domain 281 438 4.3E-32 T 14-10-2018 IPR000160 GGDEF domain A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 SMART SM00091 155 221 1.3E-8 T 14-10-2018 IPR000014 PAS domain A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 Gene3D G3DSA:3.20.20.450 455 689 1.5E-41 T 14-10-2018 IPR035919 EAL domain superfamily A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 Pfam PF00563 EAL domain 465 688 1.9E-33 T 14-10-2018 IPR001633 EAL domain A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 SMART SM00052 453 688 9.1E-10 T 14-10-2018 IPR001633 EAL domain A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 277 442 1.3E-27 T 14-10-2018 IPR000160 GGDEF domain A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 Pfam PF00989 PAS fold 156 262 9.9E-9 T 14-10-2018 IPR013767 PAS fold GO:0006355 A4R43_00095 1984b48a0add45d53ef91db75d867e2a 689 SUPERFAMILY SSF55785 144 265 1.09E-15 T 14-10-2018 IPR035965 PAS domain superfamily A4R43_17695 1f902e8718bd9bad22e1b5e0a46a9b13 274 Gene3D G3DSA:1.10.760.10 15 138 7.0E-13 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4R43_17695 1f902e8718bd9bad22e1b5e0a46a9b13 274 Gene3D G3DSA:1.10.760.10 141 233 1.0E-14 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4R43_17695 1f902e8718bd9bad22e1b5e0a46a9b13 274 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 156 228 4.0E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_17695 1f902e8718bd9bad22e1b5e0a46a9b13 274 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 59 134 3.8E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_17695 1f902e8718bd9bad22e1b5e0a46a9b13 274 SUPERFAMILY SSF46626 140 230 8.02E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4R43_17695 1f902e8718bd9bad22e1b5e0a46a9b13 274 PIRSF PIRSF000007 1 274 1.1E-118 T 14-10-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 A4R43_17695 1f902e8718bd9bad22e1b5e0a46a9b13 274 SUPERFAMILY SSF46626 27 140 2.4E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4R43_39320 04523ac80e763f88f8a510c71781f4b0 190 Gene3D G3DSA:3.40.50.620 1 189 3.8E-61 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_39320 04523ac80e763f88f8a510c71781f4b0 190 Pfam PF01467 Cytidylyltransferase-like 2 160 1.8E-27 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4R43_39320 04523ac80e763f88f8a510c71781f4b0 190 SUPERFAMILY SSF52374 1 187 2.56E-52 T 14-10-2018 A4R43_39320 04523ac80e763f88f8a510c71781f4b0 190 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 186 27.155 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A4R43_39320 04523ac80e763f88f8a510c71781f4b0 190 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 62 1.2E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4R43_39320 04523ac80e763f88f8a510c71781f4b0 190 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 1 185 1.2E-53 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 Pfam PF00970 Oxidoreductase FAD-binding domain 104 197 2.0E-14 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 SUPERFAMILY SSF54292 5 85 6.55E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 Gene3D G3DSA:3.40.50.80 201 334 7.6E-27 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 SUPERFAMILY SSF63380 97 195 1.11E-24 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 299 307 6.0E-19 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 210 229 6.0E-19 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 146 153 6.0E-19 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 129 141 6.0E-19 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 235 244 6.0E-19 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 Gene3D G3DSA:3.10.20.30 1 88 6.6E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 SUPERFAMILY SSF52343 203 333 6.29E-33 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 35 43 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 210 229 3.4E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 129 139 3.4E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 235 244 3.4E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 146 153 3.4E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 Gene3D G3DSA:2.40.30.10 95 194 2.3E-25 T 14-10-2018 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 80 7.6E-16 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_00750 55fd30ef2bff6f11c95854f701dda04c 334 Pfam PF00175 Oxidoreductase NAD-binding domain 211 311 1.5E-14 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_00100 d19a865ac8f38d7087cf8238e1ce1bbb 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.7E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00100 d19a865ac8f38d7087cf8238e1ce1bbb 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 9.7E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00100 d19a865ac8f38d7087cf8238e1ce1bbb 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 6.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00100 d19a865ac8f38d7087cf8238e1ce1bbb 187 SUPERFAMILY SSF46689 1 73 1.03E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00100 d19a865ac8f38d7087cf8238e1ce1bbb 187 Gene3D G3DSA:1.10.357.10 1 181 1.2E-49 T 14-10-2018 A4R43_00100 d19a865ac8f38d7087cf8238e1ce1bbb 187 Pfam PF13305 WHG domain 82 162 3.2E-18 T 14-10-2018 IPR025996 WHG domain A4R43_00100 d19a865ac8f38d7087cf8238e1ce1bbb 187 SUPERFAMILY SSF48498 78 179 2.22E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11485 c6c0842c1c250aeb4fef5f933c23a41a 299 SUPERFAMILY SSF161098 42 284 1.27E-52 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_11485 c6c0842c1c250aeb4fef5f933c23a41a 299 SUPERFAMILY SSF160964 3 46 2.62E-6 T 14-10-2018 A4R43_11485 c6c0842c1c250aeb4fef5f933c23a41a 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 285 1.5E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_11485 c6c0842c1c250aeb4fef5f933c23a41a 299 Gene3D G3DSA:1.10.3720.10 38 295 3.8E-61 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_24345 e889b84fca55dc491f98841e93bd7755 310 SUPERFAMILY SSF53474 27 301 1.11E-67 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_24345 e889b84fca55dc491f98841e93bd7755 310 Pfam PF07859 alpha/beta hydrolase fold 74 280 6.7E-66 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_24345 e889b84fca55dc491f98841e93bd7755 310 Gene3D G3DSA:3.40.50.1820 4 304 4.2E-81 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_33280 4efd94fe0f6cebec8650210dd4b2ecf8 284 Gene3D G3DSA:3.90.550.10 3 225 5.2E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_33280 4efd94fe0f6cebec8650210dd4b2ecf8 284 SUPERFAMILY SSF53448 5 250 5.33E-34 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_33280 4efd94fe0f6cebec8650210dd4b2ecf8 284 Pfam PF00535 Glycosyl transferase family 2 4 122 1.0E-13 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 Gene3D G3DSA:3.40.50.1820 1 280 3.1E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 Pfam PF00561 alpha/beta hydrolase fold 17 267 2.2E-30 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 PRINTS PR00412 Epoxide hydrolase signature 20 38 7.6E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 PRINTS PR00412 Epoxide hydrolase signature 222 238 7.6E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 PRINTS PR00412 Epoxide hydrolase signature 255 277 7.6E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 PRINTS PR00412 Epoxide hydrolase signature 98 111 7.6E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 SUPERFAMILY SSF53474 3 279 1.22E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 1.4E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 1.4E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_35870 87414cf4ea7fbbbe318f5fba87daedbe 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 1.4E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_35800 822253d1a74aad5155f09853bc3f064b 208 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 11 199 1.1E-43 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4R43_35800 822253d1a74aad5155f09853bc3f064b 208 Pfam PF01914 MarC family integral membrane protein 11 204 1.3E-47 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 SUPERFAMILY SSF51604 138 418 1.36E-125 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 PRINTS PR00148 Enolase signature 332 346 1.1E-49 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 PRINTS PR00148 Enolase signature 361 378 1.1E-49 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 PRINTS PR00148 Enolase signature 37 51 1.1E-49 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 PRINTS PR00148 Enolase signature 161 174 1.1E-49 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 PRINTS PR00148 Enolase signature 309 320 1.1E-49 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 PRINTS PR00148 Enolase signature 107 123 1.1E-49 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 Hamap MF_00318 Enolase [eno]. 2 409 45.525 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 Gene3D G3DSA:3.30.390.10 1 126 1.1E-52 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 Pfam PF03952 Enolase, N-terminal domain 4 134 3.5E-56 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 8.1E-203 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 SUPERFAMILY SSF54826 4 136 3.54E-51 T 14-10-2018 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 418 6.6E-127 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 ProSitePatterns PS00164 Enolase signature. 332 345 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 SMART SM01193 4 134 5.6E-84 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 PIRSF PIRSF001400 1 422 1.7E-188 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 SMART SM01192 139 423 1.4E-211 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4R43_23920 c8f3c7c4b53b906f0f7835f5fe3c1713 428 Gene3D G3DSA:3.20.20.120 128 423 7.8E-132 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_01870 1af3b123496b15d5f77efafe69852944 327 Pfam PF12833 Helix-turn-helix domain 243 322 1.0E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_01870 1af3b123496b15d5f77efafe69852944 327 Gene3D G3DSA:3.40.50.880 3 220 3.5E-60 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_01870 1af3b123496b15d5f77efafe69852944 327 SUPERFAMILY SSF46689 274 324 1.03E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01870 1af3b123496b15d5f77efafe69852944 327 SUPERFAMILY SSF52317 6 202 9.38E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_01870 1af3b123496b15d5f77efafe69852944 327 SUPERFAMILY SSF46689 221 270 8.6E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01870 1af3b123496b15d5f77efafe69852944 327 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 274 316 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_01870 1af3b123496b15d5f77efafe69852944 327 Pfam PF01965 DJ-1/PfpI family 6 182 1.4E-24 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_01870 1af3b123496b15d5f77efafe69852944 327 Gene3D G3DSA:1.10.10.60 221 324 1.7E-28 T 14-10-2018 A4R43_01870 1af3b123496b15d5f77efafe69852944 327 SMART SM00342 237 320 3.1E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_37170 f5299c0c7489a404019a5646ceb5582f 418 Gene3D G3DSA:3.30.470.20 109 409 1.4E-44 T 14-10-2018 A4R43_37170 f5299c0c7489a404019a5646ceb5582f 418 SUPERFAMILY SSF56059 92 327 5.83E-36 T 14-10-2018 A4R43_37170 f5299c0c7489a404019a5646ceb5582f 418 Pfam PF13535 ATP-grasp domain 151 296 6.6E-8 T 14-10-2018 A4R43_06620 db22b4eb91fd04038ea3bc83b606b61e 623 Gene3D G3DSA:2.160.20.10 79 198 1.3E-5 T 14-10-2018 IPR012334 Pectin lyase fold A4R43_06620 db22b4eb91fd04038ea3bc83b606b61e 623 SUPERFAMILY SSF51126 79 570 7.16E-16 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_25470 3ca71bcced883535c75956ad75f98045 130 Pfam PF03061 Thioesterase superfamily 43 120 3.1E-15 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_25470 3ca71bcced883535c75956ad75f98045 130 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 13 128 2.0E-25 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A4R43_25470 3ca71bcced883535c75956ad75f98045 130 Gene3D G3DSA:3.10.129.10 5 130 3.0E-31 T 14-10-2018 A4R43_25470 3ca71bcced883535c75956ad75f98045 130 SUPERFAMILY SSF54637 6 128 1.81E-27 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 Gene3D G3DSA:2.30.40.10 4 485 2.1E-286 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 SUPERFAMILY SSF51338 428 482 9.5E-5 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 Hamap MF_01953 Urease subunit alpha [ureC]. 2 572 55.263 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 ProSitePatterns PS01120 Urease nickel ligands signature. 133 146 - T 14-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 SUPERFAMILY SSF51556 135 572 1.79E-182 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 3 572 1.6E-269 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 301 318 4.8E-33 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 340 356 4.8E-33 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 406 421 4.8E-33 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 432 445 4.8E-33 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 124 2.2E-52 T 14-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 ProSitePatterns PS00145 Urease active site. 323 339 - T 14-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 Pfam PF01979 Amidohydrolase family 131 455 3.0E-69 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 SUPERFAMILY SSF51338 3 182 4.32E-57 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25620 29eb5a2c8c9c565d428efc75758e338d 572 Gene3D G3DSA:3.20.20.140 135 572 2.1E-286 T 14-10-2018 A4R43_21365 22bac9b7f1ae4c17cb19c254f9525fbf 232 Gene3D G3DSA:3.30.530.20 6 136 4.3E-13 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_21365 22bac9b7f1ae4c17cb19c254f9525fbf 232 SUPERFAMILY SSF55961 7 120 2.26E-17 T 14-10-2018 A4R43_20545 2e8dcb755b2adead9818464b14354b9e 231 SMART SM00849 17 211 1.4E-32 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_20545 2e8dcb755b2adead9818464b14354b9e 231 Pfam PF00753 Metallo-beta-lactamase superfamily 18 211 1.1E-28 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_20545 2e8dcb755b2adead9818464b14354b9e 231 SUPERFAMILY SSF56281 2 225 6.81E-49 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_20545 2e8dcb755b2adead9818464b14354b9e 231 Gene3D G3DSA:3.60.15.10 1 228 3.2E-50 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_27740 127d7e940a17f4ef2c92558fce1ff819 165 SUPERFAMILY SSF50475 14 136 1.31E-12 T 14-10-2018 A4R43_27740 127d7e940a17f4ef2c92558fce1ff819 165 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 91 2.3E-4 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_27740 127d7e940a17f4ef2c92558fce1ff819 165 Gene3D G3DSA:2.30.110.10 7 133 4.0E-11 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 Pfam PF00581 Rhodanese-like domain 29 116 4.0E-14 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 Pfam PF00581 Rhodanese-like domain 146 270 3.3E-13 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 ProSitePatterns PS00380 Rhodanese signature 1. 33 44 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 SUPERFAMILY SSF52821 3 135 7.99E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 SUPERFAMILY SSF52821 140 281 3.14E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 Gene3D G3DSA:3.40.250.10 140 284 2.2E-36 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 ProSitePatterns PS00683 Rhodanese C-terminal signature. 260 270 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 Gene3D G3DSA:3.40.250.10 1 139 3.3E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 SMART SM00450 142 276 7.6E-17 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_21540 5e697596eedbad979481ae9f5cea1301 285 SMART SM00450 7 120 8.4E-17 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_16925 c2b626854603cd7afec03dc03af00368 251 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 13 219 1.3E-42 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16925 c2b626854603cd7afec03dc03af00368 251 Pfam PF13183 4Fe-4S dicluster domain 140 216 1.4E-14 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_16925 c2b626854603cd7afec03dc03af00368 251 Gene3D G3DSA:3.10.20.30 3 103 8.9E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_16925 c2b626854603cd7afec03dc03af00368 251 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 105 8.0E-28 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16925 c2b626854603cd7afec03dc03af00368 251 SUPERFAMILY SSF54292 3 103 3.01E-24 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_16925 c2b626854603cd7afec03dc03af00368 251 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_16925 c2b626854603cd7afec03dc03af00368 251 SUPERFAMILY SSF46548 124 228 1.62E-17 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_16925 c2b626854603cd7afec03dc03af00368 251 Gene3D G3DSA:1.10.1060.10 107 234 3.9E-15 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_21570 53d279453eedc3840345f9cabb013b2f 180 Pfam PF01613 Flavin reductase like domain 31 179 4.2E-39 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4R43_21570 53d279453eedc3840345f9cabb013b2f 180 Gene3D G3DSA:2.30.110.10 10 180 8.5E-56 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_21570 53d279453eedc3840345f9cabb013b2f 180 SUPERFAMILY SSF50475 27 179 6.87E-49 T 14-10-2018 A4R43_21570 53d279453eedc3840345f9cabb013b2f 180 SMART SM00903 31 178 2.9E-60 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 Gene3D G3DSA:3.40.50.10860 3 329 5.4E-96 T 14-10-2018 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 158 223 3.8E-7 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 PIRSF PIRSF000188 1 332 3.0E-85 T 14-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 SUPERFAMILY SSF53223 4 130 3.52E-29 T 14-10-2018 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 SMART SM00997 151 275 0.0077 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 15 115 2.5E-16 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 SUPERFAMILY SSF51735 134 314 1.0E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 119 141 2.5E-13 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 163 183 2.5E-13 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 272 283 2.5E-13 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 51 65 2.5E-13 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 Gene3D G3DSA:3.40.50.720 121 323 5.4E-96 T 14-10-2018 A4R43_37595 85984d5be2bd539a2751b92ab6a846f3 332 SMART SM00839 129 331 1.6E-17 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_10490 2d4bab199ff63ffd809222bc975f193e 240 PIRSF PIRSF036625 1 240 6.8E-51 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4R43_10490 2d4bab199ff63ffd809222bc975f193e 240 SMART SM01012 175 230 2.1E-22 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_10490 2d4bab199ff63ffd809222bc975f193e 240 Gene3D G3DSA:3.30.450.40 2 176 1.4E-14 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_10490 2d4bab199ff63ffd809222bc975f193e 240 Pfam PF13185 GAF domain 21 163 7.9E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_10490 2d4bab199ff63ffd809222bc975f193e 240 Gene3D G3DSA:1.10.10.10 177 235 7.3E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10490 2d4bab199ff63ffd809222bc975f193e 240 SUPERFAMILY SSF52172 155 229 2.48E-11 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_10490 2d4bab199ff63ffd809222bc975f193e 240 Pfam PF03861 ANTAR domain 178 229 2.0E-20 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_10490 2d4bab199ff63ffd809222bc975f193e 240 SUPERFAMILY SSF55781 24 171 1.24E-12 T 14-10-2018 A4R43_07880 e677c3765d781a3b4f810915e1417574 285 Pfam PF00196 Bacterial regulatory proteins, luxR family 214 264 1.5E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07880 e677c3765d781a3b4f810915e1417574 285 Gene3D G3DSA:1.25.40.10 2 201 4.7E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_07880 e677c3765d781a3b4f810915e1417574 285 Gene3D G3DSA:1.10.10.10 206 278 1.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07880 e677c3765d781a3b4f810915e1417574 285 SMART SM00421 211 268 6.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07880 e677c3765d781a3b4f810915e1417574 285 SUPERFAMILY SSF48452 31 183 3.64E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_07880 e677c3765d781a3b4f810915e1417574 285 SUPERFAMILY SSF46894 207 264 1.22E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_40260 0291c25b683e4fa17fb48e6524a41c7b 412 Gene3D G3DSA:3.40.50.1820 26 251 7.7E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40260 0291c25b683e4fa17fb48e6524a41c7b 412 Pfam PF00561 alpha/beta hydrolase fold 48 194 4.7E-19 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_40260 0291c25b683e4fa17fb48e6524a41c7b 412 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 49 57 5.4E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_40260 0291c25b683e4fa17fb48e6524a41c7b 412 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 137 151 5.4E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_40260 0291c25b683e4fa17fb48e6524a41c7b 412 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 82 93 5.4E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_40260 0291c25b683e4fa17fb48e6524a41c7b 412 SUPERFAMILY SSF53474 33 395 2.83E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_05020 a161744fe985cea95b92af96ce0ca2cc 323 Pfam PF02628 Cytochrome oxidase assembly protein 21 200 1.3E-10 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 A4R43_38740 88a547f8404367fb2a79f568c1b77660 106 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 1.4E-22 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_38740 88a547f8404367fb2a79f568c1b77660 106 SUPERFAMILY SSF46785 10 103 2.02E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38740 88a547f8404367fb2a79f568c1b77660 106 Gene3D G3DSA:1.10.10.10 1 104 1.3E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 SMART SM00344 12 116 2.8E-32 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 Pfam PF13404 AsnC-type helix-turn-helix domain 12 52 1.9E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 SUPERFAMILY SSF46785 12 59 8.14E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 SUPERFAMILY SSF54909 74 154 5.9E-11 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 Pfam PF01037 Lrp/AsnC ligand binding domain 77 146 1.5E-11 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 Gene3D G3DSA:3.30.70.920 63 154 1.1E-12 T 14-10-2018 A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 Gene3D G3DSA:1.10.10.10 9 62 9.3E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 1.4E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 1.4E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_09560 42a23bd82699881c051325a2b7b1396a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 1.4E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_39225 510bf758b98029af7b41088b23d39758 157 Pfam PF00583 Acetyltransferase (GNAT) family 60 145 1.4E-16 T 14-10-2018 IPR000182 GNAT domain A4R43_39225 510bf758b98029af7b41088b23d39758 157 Gene3D G3DSA:3.40.630.30 3 156 5.8E-39 T 14-10-2018 A4R43_39225 510bf758b98029af7b41088b23d39758 157 SUPERFAMILY SSF55729 6 150 1.89E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 2.8E-24 T 14-10-2018 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 2.8E-24 T 14-10-2018 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 PRINTS PR00419 Adrenodoxin reductase family signature 284 298 2.8E-24 T 14-10-2018 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 PRINTS PR00419 Adrenodoxin reductase family signature 210 220 2.8E-24 T 14-10-2018 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 472 1.2E-213 T 14-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 Gene3D G3DSA:3.50.50.60 404 459 9.4E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 SUPERFAMILY SSF51971 142 399 1.53E-69 T 14-10-2018 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 SUPERFAMILY SSF46548 6 153 2.3E-36 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 SUPERFAMILY SSF51971 351 465 1.53E-10 T 14-10-2018 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 26 131 2.6E-22 T 14-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 Gene3D G3DSA:1.10.1060.10 17 143 7.1E-20 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 Gene3D G3DSA:3.50.50.60 144 227 8.5E-13 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 Gene3D G3DSA:3.50.50.60 247 398 2.0E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37885 c45830bcd82096a4776f5b050b6b6a19 483 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 454 2.2E-29 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_23870 3483aff464609802603e92ffe38890d7 332 SMART SM00382 42 243 5.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_23870 3483aff464609802603e92ffe38890d7 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 324 1.1E-27 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_23870 3483aff464609802603e92ffe38890d7 332 SUPERFAMILY SSF52540 6 257 2.17E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23870 3483aff464609802603e92ffe38890d7 332 Pfam PF00005 ABC transporter 34 185 6.3E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23870 3483aff464609802603e92ffe38890d7 332 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_23870 3483aff464609802603e92ffe38890d7 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 304 5.0E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_23870 3483aff464609802603e92ffe38890d7 332 Gene3D G3DSA:3.40.50.300 4 331 2.2E-106 T 14-10-2018 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 SUPERFAMILY SSF46894 137 195 1.53E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 Pfam PF00072 Response regulator receiver domain 3 108 3.7E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 194 5.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 SMART SM00448 1 120 2.0E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 Gene3D G3DSA:3.40.50.12740 1 211 7.4E-45 T 14-10-2018 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 SMART SM00421 147 204 1.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21950 dbf35d66172137ffea1de47ccdda15e7 214 SUPERFAMILY SSF52172 1 137 5.69E-19 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_35890 a996e0542a3e152dc4985b020f929d6d 681 SUPERFAMILY SSF50692 529 677 8.82E-47 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_35890 a996e0542a3e152dc4985b020f929d6d 681 Gene3D G3DSA:2.40.40.20 557 679 3.2E-42 T 14-10-2018 A4R43_35890 a996e0542a3e152dc4985b020f929d6d 681 Gene3D G3DSA:3.40.50.740 60 524 6.2E-149 T 14-10-2018 A4R43_35890 a996e0542a3e152dc4985b020f929d6d 681 Gene3D G3DSA:3.40.228.10 133 327 6.2E-149 T 14-10-2018 A4R43_35890 a996e0542a3e152dc4985b020f929d6d 681 Pfam PF01568 Molydopterin dinucleotide binding domain 568 674 9.8E-31 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4R43_35890 a996e0542a3e152dc4985b020f929d6d 681 SUPERFAMILY SSF53706 10 553 5.23E-159 T 14-10-2018 A4R43_35890 a996e0542a3e152dc4985b020f929d6d 681 Pfam PF00384 Molybdopterin oxidoreductase 55 475 6.3E-67 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_35250 345c189f492881fbc71971385203d405 190 Gene3D G3DSA:3.40.630.30 1 182 3.7E-28 T 14-10-2018 A4R43_35250 345c189f492881fbc71971385203d405 190 Pfam PF02474 Nodulation protein A (NodA) 3 188 1.3E-32 T 14-10-2018 IPR003484 N-acyltransferase NodA GO:0005829|GO:0009877|GO:0016746 A4R43_35250 345c189f492881fbc71971385203d405 190 SUPERFAMILY SSF55729 15 171 1.8E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 SMART SM00838 615 703 7.4E-23 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 SMART SM00889 495 613 6.0E-56 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 SUPERFAMILY SSF50447 256 417 3.03E-23 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Gene3D G3DSA:2.40.30.10 310 420 7.8E-25 T 14-10-2018 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Gene3D G3DSA:3.30.70.240 619 690 5.0E-76 T 14-10-2018 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 SUPERFAMILY SSF54980 618 698 2.24E-20 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Gene3D G3DSA:3.30.230.10 499 698 5.0E-76 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Pfam PF03764 Elongation factor G, domain IV 495 612 2.4E-39 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 SUPERFAMILY SSF54980 419 490 1.15E-14 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 SMART SM00382 22 160 7.1E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Pfam PF00679 Elongation factor G C-terminus 616 697 8.8E-21 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Pfam PF03144 Elongation factor Tu domain 2 330 406 7.7E-8 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 SUPERFAMILY SSF54211 495 612 4.05E-35 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Pfam PF00009 Elongation factor Tu GTP binding domain 22 287 1.8E-32 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Gene3D G3DSA:3.40.50.300 15 292 2.0E-53 T 14-10-2018 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Pfam PF14492 Elongation Factor G, domain II 420 490 4.9E-20 T 14-10-2018 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 SUPERFAMILY SSF52540 19 288 3.06E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 Gene3D G3DSA:3.30.70.870 421 493 1.0E-16 T 14-10-2018 A4R43_04200 d9add2914f5db0ab6abcda2c7a1773da 703 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 156 1.1E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_18125 46766ae0355ec00ee545c24efed1d0ee 366 SUPERFAMILY SSF51735 141 314 1.81E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_18125 46766ae0355ec00ee545c24efed1d0ee 366 Gene3D G3DSA:3.40.50.720 10 364 4.7E-135 T 14-10-2018 A4R43_18125 46766ae0355ec00ee545c24efed1d0ee 366 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 145 364 3.4E-64 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4R43_18125 46766ae0355ec00ee545c24efed1d0ee 366 SUPERFAMILY SSF52283 9 172 1.02E-47 T 14-10-2018 A4R43_18125 46766ae0355ec00ee545c24efed1d0ee 366 SMART SM01002 150 312 3.5E-72 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4R43_18125 46766ae0355ec00ee545c24efed1d0ee 366 SMART SM01003 11 141 1.6E-60 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4R43_18125 46766ae0355ec00ee545c24efed1d0ee 366 Gene3D G3DSA:3.40.50.720 141 319 4.7E-135 T 14-10-2018 A4R43_18125 46766ae0355ec00ee545c24efed1d0ee 366 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 11 141 3.0E-41 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF08659 KR domain 1337 1508 3.5E-54 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 2.0E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 527 1.3E-17 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SUPERFAMILY SSF51735 1194 1327 3.19E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Gene3D G3DSA:3.40.47.10 25 474 1.8E-190 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Gene3D G3DSA:3.40.366.10 563 863 2.7E-166 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SMART SM00823 Phosphopantetheine attachment site 1598 1670 4.3E-31 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1625 1640 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1337 1510 7.6E-47 T 14-10-2018 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 5.3E-93 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF08990 Erythronolide synthase docking 2 25 8.0E-10 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SMART SM01294 1599 1666 3.0E-6 T 14-10-2018 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SUPERFAMILY SSF55048 686 751 6.8E-14 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SUPERFAMILY SSF53474 1628 1954 4.71E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SMART SM00824 Thioesterase 1739 1952 1.4E-97 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF00550 Phosphopantetheine attachment site 1601 1666 3.1E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SMART SM00825 Beta-ketoacyl synthase 36 462 2.4E-226 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SUPERFAMILY SSF51735 1337 1566 1.99E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF14765 Polyketide synthase dehydratase 926 1191 1.0E-55 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SUPERFAMILY SSF53901 31 399 2.66E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF00698 Acyl transferase domain 563 879 1.1E-86 T 14-10-2018 IPR014043 Acyl transferase A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Gene3D G3DSA:3.40.50.1820 1682 1956 2.0E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Gene3D G3DSA:3.10.129.110 915 1193 1.7E-101 T 14-10-2018 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SUPERFAMILY SSF101173 2 33 6.67E-6 T 14-10-2018 IPR036299 Polyketide synthase, docking domain superfmaily A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Gene3D G3DSA:3.40.50.720 1194 1580 1.3E-109 T 14-10-2018 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Pfam PF00975 Thioesterase domain 1737 1952 1.7E-22 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SUPERFAMILY SSF52151 563 847 1.8E-65 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Gene3D G3DSA:1.10.1200.10 1581 1671 5.4E-31 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 860 1.5E-115 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 Gene3D G3DSA:3.30.70.3290 477 906 2.7E-166 T 14-10-2018 A4R43_07940 4a1a38d0fde4ca0f837cfb72e17c844e 1961 SMART SM00826 926 1081 1.7E-69 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_09065 60a44cf5b046f996ca85f3b9a3ec74a7 308 Gene3D G3DSA:3.20.20.530 19 306 6.8E-93 T 14-10-2018 A4R43_09065 60a44cf5b046f996ca85f3b9a3ec74a7 308 PIRSF PIRSF000196 1 308 7.0E-113 T 14-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 A4R43_09065 60a44cf5b046f996ca85f3b9a3ec74a7 308 SUPERFAMILY SSF51730 35 304 6.67E-70 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like A4R43_09065 60a44cf5b046f996ca85f3b9a3ec74a7 308 Pfam PF01619 Proline dehydrogenase 43 299 1.2E-33 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 A4R43_34815 174a0ee68dba41b1d592c87c858e8e57 162 Gene3D G3DSA:3.40.630.30 1 134 4.4E-23 T 14-10-2018 A4R43_34815 174a0ee68dba41b1d592c87c858e8e57 162 Pfam PF00583 Acetyltransferase (GNAT) family 50 124 4.4E-13 T 14-10-2018 IPR000182 GNAT domain A4R43_34815 174a0ee68dba41b1d592c87c858e8e57 162 SUPERFAMILY SSF55729 1 128 5.06E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 Pfam PF00696 Amino acid kinase family 38 278 5.3E-44 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 PRINTS PR00474 Glutamate 5-kinase family signature 68 82 1.3E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 PRINTS PR00474 Glutamate 5-kinase family signature 251 271 1.3E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 PRINTS PR00474 Glutamate 5-kinase family signature 200 227 1.3E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 PIRSF PIRSF000728 19 300 5.5E-101 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 SUPERFAMILY SSF53633 16 302 1.31E-86 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 TIGRFAM TIGR00761 argB: acetylglutamate kinase 38 276 1.0E-79 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 Gene3D G3DSA:3.40.1160.10 14 303 3.9E-100 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4R43_14320 c18a37d767ddc3fafce2f1df814bd857 306 Hamap MF_00082 Acetylglutamate kinase [argB]. 36 294 46.863 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_34845 d24a3db91baa4b78a0fc71c21f0f735b 325 Pfam PF01791 DeoC/LacD family aldolase 66 303 3.1E-25 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A4R43_34845 d24a3db91baa4b78a0fc71c21f0f735b 325 SMART SM01133 66 306 2.9E-68 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A4R43_34845 d24a3db91baa4b78a0fc71c21f0f735b 325 SUPERFAMILY SSF51569 64 305 8.58E-71 T 14-10-2018 A4R43_34845 d24a3db91baa4b78a0fc71c21f0f735b 325 PIRSF PIRSF001357 60 315 8.2E-76 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A4R43_34845 d24a3db91baa4b78a0fc71c21f0f735b 325 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 68 285 1.1E-50 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A4R43_34845 d24a3db91baa4b78a0fc71c21f0f735b 325 Gene3D G3DSA:3.20.20.70 56 309 1.6E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_19815 e0849ebe3f870754f1800cd1c03e4280 407 Gene3D G3DSA:3.30.9.50 31 263 5.3E-56 T 14-10-2018 A4R43_19815 e0849ebe3f870754f1800cd1c03e4280 407 Gene3D G3DSA:3.50.50.60 2 334 5.3E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_19815 e0849ebe3f870754f1800cd1c03e4280 407 SUPERFAMILY SSF51905 2 358 2.44E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_19815 e0849ebe3f870754f1800cd1c03e4280 407 Pfam PF01494 FAD binding domain 2 308 3.3E-10 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_33330 a854f04aa386caff4ab7e341962a07eb 190 SUPERFAMILY SSF51161 16 158 3.05E-33 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_33330 a854f04aa386caff4ab7e341962a07eb 190 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 17 47 2.0E-6 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_33330 a854f04aa386caff4ab7e341962a07eb 190 Gene3D G3DSA:2.160.10.10 5 155 3.4E-33 T 14-10-2018 A4R43_31900 d4f11efe89491a7cae92f858ec63a692 222 Pfam PF07179 SseB protein N-terminal domain 110 210 8.4E-5 T 14-10-2018 IPR009839 SseB protein N-terminal domain A4R43_33475 2c5b4a08527a8526ca41f1669ca25108 285 Gene3D G3DSA:3.40.50.150 3 285 2.2E-95 T 14-10-2018 A4R43_33475 2c5b4a08527a8526ca41f1669ca25108 285 SUPERFAMILY SSF53335 19 270 1.83E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_33475 2c5b4a08527a8526ca41f1669ca25108 285 Pfam PF04672 S-adenosyl methyltransferase 11 284 3.8E-77 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_33475 2c5b4a08527a8526ca41f1669ca25108 285 PIRSF PIRSF017393 2 285 3.5E-79 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_02130 e51157ef4853904368f289c69aa29014 328 PIRSF PIRSF017082 2 328 4.7E-98 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_02130 e51157ef4853904368f289c69aa29014 328 Gene3D G3DSA:3.40.190.10 132 256 6.9E-68 T 14-10-2018 A4R43_02130 e51157ef4853904368f289c69aa29014 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 328 3.2E-30 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_02130 e51157ef4853904368f289c69aa29014 328 Gene3D G3DSA:3.40.190.150 36 321 6.9E-68 T 14-10-2018 A4R43_02130 e51157ef4853904368f289c69aa29014 328 SUPERFAMILY SSF53850 111 294 2.99E-8 T 14-10-2018 A4R43_35145 db4797c024a840a39296de73e7d8ae35 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35145 db4797c024a840a39296de73e7d8ae35 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35145 db4797c024a840a39296de73e7d8ae35 174 SUPERFAMILY SSF48498 78 171 7.91E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_35145 db4797c024a840a39296de73e7d8ae35 174 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.1E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35145 db4797c024a840a39296de73e7d8ae35 174 SUPERFAMILY SSF46689 4 78 1.8E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35145 db4797c024a840a39296de73e7d8ae35 174 Gene3D G3DSA:1.10.357.10 1 174 2.6E-39 T 14-10-2018 A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 Pfam PF02779 Transketolase, pyrimidine binding domain 314 475 1.0E-39 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 SUPERFAMILY SSF52518 3 344 3.93E-67 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 620 2.0E-179 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 Pfam PF02780 Transketolase, C-terminal domain 501 613 2.1E-25 T 14-10-2018 IPR033248 Transketolase, C-terminal domain A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 SUPERFAMILY SSF52518 294 477 1.3E-55 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 Gene3D G3DSA:3.40.50.920 499 625 4.0E-28 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 622 40.596 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 280 1.2E-104 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 SUPERFAMILY SSF52922 500 620 1.44E-24 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 Gene3D G3DSA:3.40.50.970 313 485 1.7E-59 T 14-10-2018 A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 SMART SM00861 315 480 1.1E-56 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_13975 282ea97dc25769ecdfd360a77e97ee7f 639 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 Gene3D G3DSA:3.40.50.12740 1 207 1.4E-42 T 14-10-2018 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 6.9E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 SMART SM00448 1 120 1.9E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 SUPERFAMILY SSF46894 133 195 1.46E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 SUPERFAMILY SSF52172 2 131 2.7E-17 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.2E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.2E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.2E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 SMART SM00421 148 210 5.3E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_18155 544e0b7c7a795dfa2f9025c90a7397aa 214 Pfam PF00072 Response regulator receiver domain 3 108 1.9E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_38820 f0b7f27157fc03181a283710bd01ee40 141 SUPERFAMILY SSF54637 7 134 3.84E-25 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_38820 f0b7f27157fc03181a283710bd01ee40 141 Pfam PF13279 Thioesterase-like superfamily 10 121 1.6E-10 T 14-10-2018 A4R43_38820 f0b7f27157fc03181a283710bd01ee40 141 Gene3D G3DSA:3.10.129.10 2 139 3.8E-30 T 14-10-2018 A4R43_27945 4f3c4582d3be10787cdca8e7ad7fcbf5 209 Pfam PF13460 NAD(P)H-binding 8 198 1.5E-28 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_27945 4f3c4582d3be10787cdca8e7ad7fcbf5 209 SUPERFAMILY SSF51735 3 207 1.85E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_27945 4f3c4582d3be10787cdca8e7ad7fcbf5 209 Gene3D G3DSA:3.40.50.720 4 209 3.8E-49 T 14-10-2018 A4R43_37480 cbbbb1f5125485e9e2df61e3c143cc58 219 Pfam PF00072 Response regulator receiver domain 3 112 2.1E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_37480 cbbbb1f5125485e9e2df61e3c143cc58 219 SUPERFAMILY SSF46894 120 217 1.05E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37480 cbbbb1f5125485e9e2df61e3c143cc58 219 Gene3D G3DSA:1.10.10.10 123 219 1.2E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37480 cbbbb1f5125485e9e2df61e3c143cc58 219 SMART SM00862 145 217 6.3E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37480 cbbbb1f5125485e9e2df61e3c143cc58 219 SUPERFAMILY SSF52172 2 118 5.27E-31 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_37480 cbbbb1f5125485e9e2df61e3c143cc58 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 217 2.2E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37480 cbbbb1f5125485e9e2df61e3c143cc58 219 Gene3D G3DSA:3.40.50.2300 1 121 2.1E-31 T 14-10-2018 A4R43_37480 cbbbb1f5125485e9e2df61e3c143cc58 219 SMART SM00448 1 112 2.0E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_33565 10f9a2c7155a409c2a51a7d3507fa190 239 SUPERFAMILY SSF56808 6 225 1.31E-80 T 14-10-2018 IPR023674 Ribosomal protein L1-like A4R43_33565 10f9a2c7155a409c2a51a7d3507fa190 239 Gene3D G3DSA:3.30.190.20 25 225 5.1E-80 T 14-10-2018 A4R43_33565 10f9a2c7155a409c2a51a7d3507fa190 239 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 2.6E-50 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A4R43_33565 10f9a2c7155a409c2a51a7d3507fa190 239 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.132 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A4R43_33565 10f9a2c7155a409c2a51a7d3507fa190 239 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 1.5E-100 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A4R43_33565 10f9a2c7155a409c2a51a7d3507fa190 239 Gene3D G3DSA:3.40.50.790 68 159 5.1E-80 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A4R43_33565 10f9a2c7155a409c2a51a7d3507fa190 239 PIRSF PIRSF002155 1 227 1.2E-73 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33565 10f9a2c7155a409c2a51a7d3507fa190 239 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_32770 d9ce6b110a5757f7f5264fcf18700916 304 Gene3D G3DSA:3.40.630.30 25 302 1.6E-19 T 14-10-2018 A4R43_32770 d9ce6b110a5757f7f5264fcf18700916 304 SUPERFAMILY SSF55729 43 292 6.31E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_32770 d9ce6b110a5757f7f5264fcf18700916 304 Pfam PF00583 Acetyltransferase (GNAT) family 199 290 2.2E-7 T 14-10-2018 IPR000182 GNAT domain A4R43_25165 5a815fb1bdff284d1045afa6709b1f47 217 SMART SM00382 27 214 2.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_25165 5a815fb1bdff284d1045afa6709b1f47 217 Pfam PF00005 ABC transporter 18 166 2.6E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_25165 5a815fb1bdff284d1045afa6709b1f47 217 SUPERFAMILY SSF52540 1 216 4.8E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25165 5a815fb1bdff284d1045afa6709b1f47 217 Gene3D G3DSA:3.40.50.300 1 217 2.0E-69 T 14-10-2018 A4R43_25165 5a815fb1bdff284d1045afa6709b1f47 217 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 SUPERFAMILY SSF51445 25 400 2.74E-109 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 Gene3D G3DSA:3.40.50.1700 387 605 7.9E-78 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 SUPERFAMILY SSF52279 402 602 1.18E-51 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 Gene3D G3DSA:3.20.20.300 23 385 1.7E-130 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 PRINTS PR00133 Glycosyl hydrolase family 3 signature 107 123 3.6E-22 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 PRINTS PR00133 Glycosyl hydrolase family 3 signature 283 301 3.6E-22 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 PRINTS PR00133 Glycosyl hydrolase family 3 signature 177 193 3.6E-22 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 PRINTS PR00133 Glycosyl hydrolase family 3 signature 131 150 3.6E-22 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 PRINTS PR00133 Glycosyl hydrolase family 3 signature 213 229 3.6E-22 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 402 602 1.3E-40 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 48 363 1.8E-73 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_35125 d4a1f23bb023130af8c6ddb4acba8e7a 605 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 283 300 - T 14-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 PIRSF PIRSF000429 2 403 3.6E-109 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 401 3.1E-129 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 Gene3D G3DSA:3.40.47.10 7 300 2.6E-146 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 Gene3D G3DSA:3.40.47.10 126 398 2.6E-146 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 ProSitePatterns PS00099 Thiolases active site. 384 397 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 SUPERFAMILY SSF53901 281 402 6.84E-44 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 SUPERFAMILY SSF53901 3 277 1.29E-64 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 Pfam PF00108 Thiolase, N-terminal domain 6 229 2.8E-46 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 ProSitePatterns PS00737 Thiolases signature 2. 349 365 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A4R43_22855 b767198b916bd81014aab4f7ef75b3b5 403 Pfam PF02803 Thiolase, C-terminal domain 281 402 2.4E-46 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_31770 e93502fa262e575b326048ec896c1e87 197 Gene3D G3DSA:1.10.357.10 5 197 2.7E-35 T 14-10-2018 A4R43_31770 e93502fa262e575b326048ec896c1e87 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 6.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31770 e93502fa262e575b326048ec896c1e87 197 SUPERFAMILY SSF46689 8 71 6.16E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31770 e93502fa262e575b326048ec896c1e87 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31770 e93502fa262e575b326048ec896c1e87 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 SUPERFAMILY SSF47203 241 395 8.7E-55 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 Gene3D G3DSA:1.10.540.10 2 122 1.6E-38 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 4.9E-35 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 242 390 1.3E-47 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 228 9.0E-22 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 SUPERFAMILY SSF56645 9 251 1.57E-73 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 PIRSF PIRSF016578 5 194 3.6E-8 T 14-10-2018 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 PIRSF PIRSF016578 231 374 7.2E-11 T 14-10-2018 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 Gene3D G3DSA:1.20.140.10 248 395 2.6E-50 T 14-10-2018 A4R43_35700 f2903c3f30f0837530058f2926265cb4 398 Gene3D G3DSA:2.40.110.10 125 247 2.8E-35 T 14-10-2018 A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 SMART SM00487 26 222 8.4E-22 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 SUPERFAMILY SSF53271 580 706 9.57E-10 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 Gene3D G3DSA:3.40.50.300 6 214 8.7E-53 T 14-10-2018 A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 Pfam PF16124 RecQ zinc-binding 446 491 7.5E-7 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 152 161 - T 14-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 Gene3D G3DSA:3.40.50.2020 577 709 2.9E-7 T 14-10-2018 A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 30 367 1.4E-65 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 Gene3D G3DSA:1.10.10.10 440 529 1.8E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 Gene3D G3DSA:3.40.50.300 228 402 9.1E-29 T 14-10-2018 A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 SUPERFAMILY SSF52540 75 369 8.5E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 Pfam PF00271 Helicase conserved C-terminal domain 256 349 8.3E-13 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 SMART SM00490 269 350 3.6E-22 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_39315 c4cc9a536c93f056a2873407a534f2cf 709 Pfam PF00270 DEAD/DEAH box helicase 33 202 5.6E-15 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_04250 f0b31219098cb0f8933f85719f3aa6eb 373 Pfam PF07730 Histidine kinase 182 242 3.0E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_04250 f0b31219098cb0f8933f85719f3aa6eb 373 SUPERFAMILY SSF55874 276 369 8.83E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_04250 f0b31219098cb0f8933f85719f3aa6eb 373 Gene3D G3DSA:3.30.565.10 251 370 3.4E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_11330 6d2a9cdcb4d5fb1a113eff10074ed9fb 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11330 6d2a9cdcb4d5fb1a113eff10074ed9fb 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 4.0E-22 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11330 6d2a9cdcb4d5fb1a113eff10074ed9fb 54 SUPERFAMILY SSF57829 4 54 4.88E-17 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4R43_11330 6d2a9cdcb4d5fb1a113eff10074ed9fb 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.059 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11330 6d2a9cdcb4d5fb1a113eff10074ed9fb 54 Gene3D G3DSA:2.20.28.120 1 54 1.0E-24 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11330 6d2a9cdcb4d5fb1a113eff10074ed9fb 54 Pfam PF00471 Ribosomal protein L33 9 53 1.7E-16 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_32220 8988904405ccde25ed82602d75c77a27 183 Gene3D G3DSA:2.60.40.200 51 181 3.9E-10 T 14-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4R43_32220 8988904405ccde25ed82602d75c77a27 183 SUPERFAMILY SSF49329 61 178 3.93E-12 T 14-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4R43_32220 8988904405ccde25ed82602d75c77a27 183 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 66 178 1.3E-6 T 14-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 Pfam PF00206 Lyase 28 303 3.9E-36 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 SUPERFAMILY SSF48557 13 438 2.83E-88 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 3.4E-15 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 3.4E-15 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 3.4E-15 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 3.4E-15 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 19 353 1.9E-111 T 14-10-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 Gene3D G3DSA:1.20.200.10 107 365 1.7E-88 T 14-10-2018 A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 Gene3D G3DSA:1.10.275.10 7 106 7.6E-30 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 PRINTS PR00145 Argininosuccinate lyase family signature 280 296 4.0E-5 T 14-10-2018 A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 4.0E-5 T 14-10-2018 A4R43_40860 eb40fcfadc9e39c153edaa8ed6b15309 442 PRINTS PR00145 Argininosuccinate lyase family signature 188 204 4.0E-5 T 14-10-2018 A4R43_37645 1b0ced3cc31314aedd1ed24558da0508 609 TIGRFAM TIGR01686 FkbH: FkbH domain 252 578 6.7E-88 T 14-10-2018 IPR010037 FkbH domain A4R43_37645 1b0ced3cc31314aedd1ed24558da0508 609 Gene3D G3DSA:3.40.50.1110 36 250 1.7E-17 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_37645 1b0ced3cc31314aedd1ed24558da0508 609 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 254 372 5.6E-16 T 14-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC A4R43_37645 1b0ced3cc31314aedd1ed24558da0508 609 SUPERFAMILY SSF55729 446 583 1.12E-10 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_37645 1b0ced3cc31314aedd1ed24558da0508 609 Gene3D G3DSA:3.40.50.1000 251 417 2.8E-49 T 14-10-2018 IPR023214 HAD superfamily A4R43_37645 1b0ced3cc31314aedd1ed24558da0508 609 SUPERFAMILY SSF56784 252 373 6.78E-9 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_37645 1b0ced3cc31314aedd1ed24558da0508 609 Gene3D G3DSA:3.40.630.30 447 582 4.2E-9 T 14-10-2018 A4R43_00420 fe4ee0e406c3a50e35baf0cc1ee4e81f 279 Gene3D G3DSA:3.40.190.150 1 276 6.5E-61 T 14-10-2018 A4R43_00420 fe4ee0e406c3a50e35baf0cc1ee4e81f 279 SUPERFAMILY SSF53850 81 200 1.55E-8 T 14-10-2018 A4R43_00420 fe4ee0e406c3a50e35baf0cc1ee4e81f 279 PIRSF PIRSF017082 1 279 2.1E-68 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_00420 fe4ee0e406c3a50e35baf0cc1ee4e81f 279 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 14 264 6.7E-25 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_00420 fe4ee0e406c3a50e35baf0cc1ee4e81f 279 Gene3D G3DSA:3.40.190.10 90 211 6.5E-61 T 14-10-2018 A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 278 289 2.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 351 370 2.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 331 339 2.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 212 438 9.4E-43 T 14-10-2018 A4R43_31090 68ffe5722f50f0f85492306a87244405 445 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 206 382 4.2E-5 T 14-10-2018 A4R43_31090 68ffe5722f50f0f85492306a87244405 445 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 338 366 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 224 1.7E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 372 389 1.7E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 325 341 1.7E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 405 425 1.7E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 278 289 1.7E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 351 370 1.7E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31090 68ffe5722f50f0f85492306a87244405 445 Gene3D G3DSA:3.40.50.720 24 199 1.2E-51 T 14-10-2018 A4R43_31090 68ffe5722f50f0f85492306a87244405 445 Gene3D G3DSA:3.40.50.720 201 444 2.5E-60 T 14-10-2018 A4R43_31090 68ffe5722f50f0f85492306a87244405 445 SUPERFAMILY SSF51735 201 442 2.62E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 Gene3D G3DSA:1.25.40.80 127 269 7.1E-67 T 14-10-2018 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 SUPERFAMILY SSF52425 5 168 5.63E-46 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 Pfam PF00875 DNA photolyase 7 158 4.4E-41 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 Gene3D G3DSA:3.40.50.620 8 196 7.1E-67 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 PRINTS PR00147 DNA photolyase signature 367 381 7.9E-26 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 PRINTS PR00147 DNA photolyase signature 308 324 7.9E-26 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 PRINTS PR00147 DNA photolyase signature 328 346 7.9E-26 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 PRINTS PR00147 DNA photolyase signature 138 154 7.9E-26 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 Gene3D G3DSA:1.10.579.10 276 451 9.2E-75 T 14-10-2018 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 Pfam PF03441 FAD binding domain of DNA photolyase 256 447 3.0E-80 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 308 320 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal A4R43_25530 dbdb994e3bb3e21e3be9dc90a06934b3 452 SUPERFAMILY SSF48173 187 449 1.28E-101 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 A4R43_07590 ee11fa9acfd82f90cc3380ecaa5311b2 238 Pfam PF03861 ANTAR domain 186 227 5.3E-7 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_07590 ee11fa9acfd82f90cc3380ecaa5311b2 238 SMART SM01012 164 227 5.7E-6 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_07590 ee11fa9acfd82f90cc3380ecaa5311b2 238 SMART SM00065 22 171 1.4E-4 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_07590 ee11fa9acfd82f90cc3380ecaa5311b2 238 Gene3D G3DSA:3.30.450.40 26 174 3.1E-11 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_07590 ee11fa9acfd82f90cc3380ecaa5311b2 238 SUPERFAMILY SSF55781 30 164 9.81E-13 T 14-10-2018 A4R43_14030 742dd700251ecf00ba95d763aa09f0ea 229 Pfam PF11361 Protein of unknown function (DUF3159) 8 193 1.6E-59 T 14-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 A4R43_14030 742dd700251ecf00ba95d763aa09f0ea 229 PIRSF PIRSF010219 2 206 6.8E-61 T 14-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 A4R43_04870 71bec5af9cda4b94ef690c4b9ba46ed8 145 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 94 1.2E-11 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_04870 71bec5af9cda4b94ef690c4b9ba46ed8 145 SUPERFAMILY SSF50475 1 115 8.04E-24 T 14-10-2018 A4R43_04870 71bec5af9cda4b94ef690c4b9ba46ed8 145 Gene3D G3DSA:2.30.110.10 1 142 1.8E-26 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_04870 71bec5af9cda4b94ef690c4b9ba46ed8 145 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 138 1.1E-29 T 14-10-2018 IPR019920 F420-binding domain, putative A4R43_08340 7b008d8b907dae10efcab98db7447058 248 Gene3D G3DSA:3.40.50.720 3 248 8.2E-63 T 14-10-2018 A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 9.3E-48 T 14-10-2018 A4R43_08340 7b008d8b907dae10efcab98db7447058 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08340 7b008d8b907dae10efcab98db7447058 248 SUPERFAMILY SSF51735 5 247 1.07E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 PIRSF PIRSF000332 1 208 2.2E-19 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 PIRSF PIRSF000332 230 293 0.74 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 193 6.5E-32 T 14-10-2018 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 6.7E-12 T 14-10-2018 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 6.7E-12 T 14-10-2018 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.7E-12 T 14-10-2018 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 Gene3D G3DSA:3.50.50.60 1 353 9.1E-103 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 SUPERFAMILY SSF51905 3 184 2.2E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 159 183 1.2E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 128 1.2E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.2E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_02965 67d5c19eadee7b67a8393a70ba987b2e 355 SUPERFAMILY SSF51905 132 280 2.68E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 72 19.438 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 PRINTS PR00974 Ribosomal protein S18 family signature 45 59 3.6E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 PRINTS PR00974 Ribosomal protein S18 family signature 59 69 3.6E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 PRINTS PR00974 Ribosomal protein S18 family signature 37 44 3.6E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 PRINTS PR00974 Ribosomal protein S18 family signature 27 37 3.6E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 20 69 4.0E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 Pfam PF01084 Ribosomal protein S18 17 67 3.0E-24 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 TIGRFAM TIGR00165 S18: ribosomal protein bS18 6 69 7.2E-24 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 SUPERFAMILY SSF46911 5 70 1.09E-23 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11340 662c1e930eae0851f7df6f6500b7b742 74 Gene3D G3DSA:4.10.640.10 1 73 2.9E-26 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 Gene3D G3DSA:1.10.10.10 23 92 9.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 Gene3D G3DSA:1.20.120.530 107 245 1.6E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 3.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 3.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 Pfam PF07729 FCD domain 120 233 3.9E-19 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 SMART SM00895 113 234 4.2E-14 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 83 1.6E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 SMART SM00345 27 88 5.5E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 SUPERFAMILY SSF48008 109 241 1.39E-20 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_03720 08c88f2b357ccb218c4c029a84696300 249 SUPERFAMILY SSF46785 20 92 3.9E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 Gene3D G3DSA:1.25.40.10 675 907 9.7E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 Gene3D G3DSA:1.25.40.10 92 250 2.7E-38 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 Gene3D G3DSA:1.10.10.10 1 89 7.7E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SUPERFAMILY SSF48452 698 893 3.8E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SMART SM00028 745 778 140.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SMART SM00028 825 858 59.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SMART SM00028 706 739 100.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SMART SM00028 785 818 81.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SMART SM00028 865 898 57.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SMART SM00862 15 87 1.5E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 PRINTS PR00364 Disease resistance protein signature 450 464 1.3E-8 T 14-10-2018 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 PRINTS PR00364 Disease resistance protein signature 285 300 1.3E-8 T 14-10-2018 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 PRINTS PR00364 Disease resistance protein signature 363 377 1.3E-8 T 14-10-2018 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 Gene3D G3DSA:3.40.50.300 251 406 9.6E-29 T 14-10-2018 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SUPERFAMILY SSF48452 91 254 4.17E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 77 2.0E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SUPERFAMILY SSF52540 253 520 4.44E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SMART SM01043 94 236 1.2E-31 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 Pfam PF00931 NB-ARC domain 268 462 3.3E-8 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 Pfam PF03704 Bacterial transcriptional activator domain 94 236 1.3E-27 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_19580 4648f0f485e3bd61c2ffeee751e45afc 923 SUPERFAMILY SSF46894 2 87 1.9E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_36855 e04cf70ab9183730d6686dee34be277f 251 Gene3D G3DSA:1.10.490.10 103 226 9.8E-29 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4R43_36855 e04cf70ab9183730d6686dee34be277f 251 SUPERFAMILY SSF46458 106 216 4.32E-24 T 14-10-2018 IPR009050 Globin-like superfamily A4R43_36855 e04cf70ab9183730d6686dee34be277f 251 Gene3D G3DSA:3.30.70.100 1 95 8.3E-22 T 14-10-2018 A4R43_36855 e04cf70ab9183730d6686dee34be277f 251 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 75 4.0E-10 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4R43_36855 e04cf70ab9183730d6686dee34be277f 251 Pfam PF01152 Bacterial-like globin 106 200 6.8E-14 T 14-10-2018 IPR001486 Truncated hemoglobin GO:0019825 A4R43_36855 e04cf70ab9183730d6686dee34be277f 251 SUPERFAMILY SSF54909 2 89 2.06E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_22955 c28550a63f3e31dd31aedcd331df3385 432 Gene3D G3DSA:3.40.640.10 6 290 1.1E-102 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_22955 c28550a63f3e31dd31aedcd331df3385 432 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 425 3.0E-140 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_22955 c28550a63f3e31dd31aedcd331df3385 432 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_22955 c28550a63f3e31dd31aedcd331df3385 432 Gene3D G3DSA:3.90.1150.10 294 432 2.4E-49 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_22955 c28550a63f3e31dd31aedcd331df3385 432 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 425 2.1E-195 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 A4R43_22955 c28550a63f3e31dd31aedcd331df3385 432 SUPERFAMILY SSF53383 5 425 2.86E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_22955 c28550a63f3e31dd31aedcd331df3385 432 PIRSF PIRSF001434 1 429 9.5E-130 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_00880 866456350340c3e1bb3d360055f494ca 150 Pfam PF01475 Ferric uptake regulator family 11 123 3.9E-21 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4R43_00880 866456350340c3e1bb3d360055f494ca 150 SUPERFAMILY SSF46785 3 133 6.34E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00880 866456350340c3e1bb3d360055f494ca 150 Gene3D G3DSA:3.30.1490.190 83 146 9.7E-15 T 14-10-2018 A4R43_00880 866456350340c3e1bb3d360055f494ca 150 Gene3D G3DSA:1.10.10.10 1 81 2.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.5E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.5E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.5E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 SUPERFAMILY SSF51735 2 251 2.74E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 1.3E-63 T 14-10-2018 A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 3.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 Gene3D G3DSA:3.40.50.720 1 255 1.2E-78 T 14-10-2018 A4R43_13420 7635f7cf86010f6e3154f1917e3d4728 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 184 1.3E-4 T 14-10-2018 A4R43_34510 e4ad50cc603e0487a88954e06c7adeea 213 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 64 1.5E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_34510 e4ad50cc603e0487a88954e06c7adeea 213 Pfam PF07729 FCD domain 74 202 2.0E-26 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_34510 e4ad50cc603e0487a88954e06c7adeea 213 SMART SM00895 74 203 8.2E-17 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_34510 e4ad50cc603e0487a88954e06c7adeea 213 Gene3D G3DSA:1.20.120.530 72 213 1.2E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_34510 e4ad50cc603e0487a88954e06c7adeea 213 Gene3D G3DSA:1.10.10.10 1 65 6.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34510 e4ad50cc603e0487a88954e06c7adeea 213 SUPERFAMILY SSF46785 2 68 1.43E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_34510 e4ad50cc603e0487a88954e06c7adeea 213 SUPERFAMILY SSF48008 73 207 4.97E-20 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_34510 e4ad50cc603e0487a88954e06c7adeea 213 SMART SM00345 6 64 1.3E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_24495 8d2577e7784f0a2c63b9c536306895c1 534 SUPERFAMILY SSF56762 183 533 4.19E-81 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24495 8d2577e7784f0a2c63b9c536306895c1 534 Pfam PF00374 Nickel-dependent hydrogenase 211 278 6.6E-8 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A4R43_24495 8d2577e7784f0a2c63b9c536306895c1 534 Gene3D G3DSA:1.10.645.20 174 533 1.9E-92 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24495 8d2577e7784f0a2c63b9c536306895c1 534 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 287 529 4.4E-24 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24495 8d2577e7784f0a2c63b9c536306895c1 534 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 95 148 1.0E-14 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24495 8d2577e7784f0a2c63b9c536306895c1 534 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 52 148 4.8E-13 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24495 8d2577e7784f0a2c63b9c536306895c1 534 SUPERFAMILY SSF143243 53 187 3.01E-24 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24495 8d2577e7784f0a2c63b9c536306895c1 534 Gene3D G3DSA:3.30.460.80 43 131 1.4E-7 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_31575 c57756dba599fb637d9c860c70e680ac 462 Pfam PF01565 FAD binding domain 42 180 9.8E-43 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_31575 c57756dba599fb637d9c860c70e680ac 462 SUPERFAMILY SSF55103 223 460 3.92E-57 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_31575 c57756dba599fb637d9c860c70e680ac 462 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 458 4.3E-61 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_31575 c57756dba599fb637d9c860c70e680ac 462 Gene3D G3DSA:3.30.70.2740 337 419 9.0E-14 T 14-10-2018 A4R43_31575 c57756dba599fb637d9c860c70e680ac 462 Gene3D G3DSA:1.10.45.10 420 459 2.4E-11 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4R43_31575 c57756dba599fb637d9c860c70e680ac 462 Gene3D G3DSA:3.30.465.40 4 233 3.1E-73 T 14-10-2018 A4R43_31575 c57756dba599fb637d9c860c70e680ac 462 SUPERFAMILY SSF56176 4 218 4.67E-76 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 577 787 1.2E-77 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Gene3D G3DSA:3.30.230.10 600 794 1.4E-73 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 TIGRFAM TIGR00763 lon: endopeptidase La 8 786 1.1E-245 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 199 1.2E-20 T 14-10-2018 IPR003111 Lon, substrate-binding domain A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Gene3D G3DSA:3.40.50.300 312 496 9.0E-61 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Gene3D G3DSA:2.30.130.40 1 110 7.1E-13 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 691 699 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Gene3D G3DSA:1.10.8.60 497 591 3.6E-25 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 SUPERFAMILY SSF52540 304 562 3.62E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 PIRSF PIRSF001174 1 789 3.0E-251 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 SUPERFAMILY SSF88697 7 198 6.46E-20 T 14-10-2018 IPR015947 PUA-like superfamily A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 SUPERFAMILY SSF54211 607 785 6.07E-52 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Hamap MF_01973 Lon protease [lon]. 7 787 58.511 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 718 737 2.5E-51 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 741 759 2.5E-51 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 607 623 2.5E-51 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 688 707 2.5E-51 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 362 381 2.5E-51 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 SMART SM00464 6 201 3.6E-21 T 14-10-2018 IPR003111 Lon, substrate-binding domain A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 359 494 1.1E-19 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 Gene3D G3DSA:1.20.58.1480 133 244 2.2E-23 T 14-10-2018 A4R43_33470 567811792b98f687dc1778ffb5c21f07 797 SMART SM00382 354 507 3.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_18320 5f4c8fde5c4f8c6e64db54836acf3b81 276 Pfam PF12833 Helix-turn-helix domain 181 259 3.0E-16 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_18320 5f4c8fde5c4f8c6e64db54836acf3b81 276 SMART SM00342 175 259 9.5E-12 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_18320 5f4c8fde5c4f8c6e64db54836acf3b81 276 Gene3D G3DSA:1.10.10.60 168 262 4.0E-19 T 14-10-2018 A4R43_10845 cae42da58d9c7deac90262258f2a3b24 257 SUPERFAMILY SSF54637 120 256 5.15E-11 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_10845 cae42da58d9c7deac90262258f2a3b24 257 Gene3D G3DSA:3.10.129.90 22 255 4.8E-17 T 14-10-2018 A4R43_10845 cae42da58d9c7deac90262258f2a3b24 257 Pfam PF13622 Thioesterase-like superfamily 20 254 3.3E-40 T 14-10-2018 A4R43_15160 892ac370f680830a39650e15037648ef 218 SUPERFAMILY SSF52172 1 188 2.11E-37 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_15160 892ac370f680830a39650e15037648ef 218 Pfam PF00072 Response regulator receiver domain 6 117 3.5E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15160 892ac370f680830a39650e15037648ef 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15160 892ac370f680830a39650e15037648ef 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15160 892ac370f680830a39650e15037648ef 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15160 892ac370f680830a39650e15037648ef 218 SMART SM00448 4 117 2.7E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15160 892ac370f680830a39650e15037648ef 218 Gene3D G3DSA:3.40.50.12740 4 218 5.4E-73 T 14-10-2018 A4R43_15160 892ac370f680830a39650e15037648ef 218 SMART SM00421 155 212 8.0E-27 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15160 892ac370f680830a39650e15037648ef 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 3.5E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15160 892ac370f680830a39650e15037648ef 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25460 dc6b51c5854dcbf829955a8aec67b290 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_25460 dc6b51c5854dcbf829955a8aec67b290 542 Pfam PF00501 AMP-binding enzyme 28 438 1.5E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_25460 dc6b51c5854dcbf829955a8aec67b290 542 Gene3D G3DSA:3.40.50.12780 1 433 1.5E-114 T 14-10-2018 A4R43_25460 dc6b51c5854dcbf829955a8aec67b290 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 522 1.2E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_25460 dc6b51c5854dcbf829955a8aec67b290 542 SUPERFAMILY SSF56801 10 532 1.96E-141 T 14-10-2018 A4R43_25460 dc6b51c5854dcbf829955a8aec67b290 542 Gene3D G3DSA:3.30.300.310 434 535 4.0E-35 T 14-10-2018 A4R43_16010 1809ee8f24a2f5a4a3100ee5a538a3d6 374 Gene3D G3DSA:1.20.140.10 233 373 4.3E-28 T 14-10-2018 A4R43_16010 1809ee8f24a2f5a4a3100ee5a538a3d6 374 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 216 1.4E-17 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_16010 1809ee8f24a2f5a4a3100ee5a538a3d6 374 SUPERFAMILY SSF47203 228 369 3.38E-20 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16010 1809ee8f24a2f5a4a3100ee5a538a3d6 374 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 1.2E-16 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_16010 1809ee8f24a2f5a4a3100ee5a538a3d6 374 SUPERFAMILY SSF56645 2 240 1.24E-60 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16010 1809ee8f24a2f5a4a3100ee5a538a3d6 374 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 367 3.3E-18 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16010 1809ee8f24a2f5a4a3100ee5a538a3d6 374 Gene3D G3DSA:1.10.540.10 2 116 2.7E-23 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16010 1809ee8f24a2f5a4a3100ee5a538a3d6 374 Gene3D G3DSA:2.40.110.10 122 232 1.4E-30 T 14-10-2018 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 Pfam PF01202 Shikimate kinase 11 166 2.7E-39 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 PRINTS PR01100 Shikimate kinase family signature 5 20 1.9E-15 T 14-10-2018 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 PRINTS PR01100 Shikimate kinase family signature 95 112 1.9E-15 T 14-10-2018 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 PRINTS PR01100 Shikimate kinase family signature 57 65 1.9E-15 T 14-10-2018 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 PRINTS PR01100 Shikimate kinase family signature 29 42 1.9E-15 T 14-10-2018 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 PRINTS PR01100 Shikimate kinase family signature 75 84 1.9E-15 T 14-10-2018 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 Gene3D G3DSA:3.40.50.300 3 179 5.7E-49 T 14-10-2018 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 ProSitePatterns PS01128 Shikimate kinase signature. 58 83 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 Hamap MF_00109 Shikimate kinase [aroK]. 2 167 25.556 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4R43_04660 c9f6e632e528ac5989f3372daf884e80 181 SUPERFAMILY SSF52540 3 166 7.7E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08965 ca56c5027e45cfcd2438f120286deea1 135 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 98 1.1E-11 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_08965 ca56c5027e45cfcd2438f120286deea1 135 SUPERFAMILY SSF50475 3 133 3.39E-23 T 14-10-2018 A4R43_08965 ca56c5027e45cfcd2438f120286deea1 135 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 6 133 3.5E-47 T 14-10-2018 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable A4R43_08965 ca56c5027e45cfcd2438f120286deea1 135 Gene3D G3DSA:2.30.110.10 3 134 1.4E-41 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_40825 36d0f6dd0eff6558de4d713e4d0e6f0f 177 SUPERFAMILY SSF47473 7 166 1.46E-25 T 14-10-2018 IPR011992 EF-hand domain pair A4R43_40825 36d0f6dd0eff6558de4d713e4d0e6f0f 177 Gene3D G3DSA:1.10.238.10 2 177 8.7E-44 T 14-10-2018 A4R43_40825 36d0f6dd0eff6558de4d713e4d0e6f0f 177 ProSitePatterns PS00018 EF-hand calcium-binding domain. 18 30 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site A4R43_40825 36d0f6dd0eff6558de4d713e4d0e6f0f 177 ProSitePatterns PS00018 EF-hand calcium-binding domain. 147 159 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site A4R43_40825 36d0f6dd0eff6558de4d713e4d0e6f0f 177 Pfam PF13405 EF-hand domain 139 164 5.6E-6 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 A4R43_40825 36d0f6dd0eff6558de4d713e4d0e6f0f 177 SMART SM00054 104 132 0.56 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 A4R43_40825 36d0f6dd0eff6558de4d713e4d0e6f0f 177 SMART SM00054 138 166 3.2E-4 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 A4R43_40825 36d0f6dd0eff6558de4d713e4d0e6f0f 177 SMART SM00054 9 37 10.0 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 A4R43_15985 cab7efaec421f86a27319feeb4d4bd5d 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 3.0E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15985 cab7efaec421f86a27319feeb4d4bd5d 205 Gene3D G3DSA:1.10.357.10 51 197 1.3E-39 T 14-10-2018 A4R43_15985 cab7efaec421f86a27319feeb4d4bd5d 205 SUPERFAMILY SSF48498 82 195 9.64E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_15985 cab7efaec421f86a27319feeb4d4bd5d 205 Gene3D G3DSA:1.10.10.60 3 50 2.4E-21 T 14-10-2018 A4R43_15985 cab7efaec421f86a27319feeb4d4bd5d 205 SUPERFAMILY SSF46689 6 84 3.49E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_15985 cab7efaec421f86a27319feeb4d4bd5d 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15985 cab7efaec421f86a27319feeb4d4bd5d 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31710 df570cf025435f5f41cc4d7761ad0ee3 608 SUPERFAMILY SSF56112 12 298 6.57E-63 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_31710 df570cf025435f5f41cc4d7761ad0ee3 608 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_31710 df570cf025435f5f41cc4d7761ad0ee3 608 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_31710 df570cf025435f5f41cc4d7761ad0ee3 608 Gene3D G3DSA:1.10.510.10 95 270 7.3E-45 T 14-10-2018 A4R43_31710 df570cf025435f5f41cc4d7761ad0ee3 608 Gene3D G3DSA:3.30.200.20 6 93 1.4E-14 T 14-10-2018 A4R43_31710 df570cf025435f5f41cc4d7761ad0ee3 608 SMART SM00220 15 264 3.1E-39 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_31710 df570cf025435f5f41cc4d7761ad0ee3 608 Pfam PF00069 Protein kinase domain 15 261 9.6E-38 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 SUPERFAMILY SSF53850 91 294 7.03E-30 T 14-10-2018 A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 Gene3D G3DSA:3.40.190.290 92 293 2.1E-35 T 14-10-2018 A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 Pfam PF03466 LysR substrate binding domain 89 289 7.5E-33 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 SUPERFAMILY SSF46785 2 109 2.18E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 Gene3D G3DSA:1.10.10.10 1 91 1.9E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.8E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17030 f56dc75db948c28c65dfac517d22de04 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 SUPERFAMILY SSF52440 1 112 7.91E-41 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Pfam PF00682 HMGL-like 525 794 8.3E-26 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1079 1096 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Gene3D G3DSA:3.20.20.70 476 987 3.8E-232 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Gene3D G3DSA:3.30.470.130 1 454 2.3E-185 T 14-10-2018 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Gene3D G3DSA:2.40.50.100 1047 1122 1.9E-18 T 14-10-2018 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Pfam PF02785 Biotin carboxylase C-terminal domain 339 447 3.7E-33 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 SUPERFAMILY SSF51246 334 451 1.88E-36 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 SUPERFAMILY SSF56059 84 358 3.89E-70 T 14-10-2018 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 PIRSF PIRSF001594 1 1123 0.0 T 14-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 2.4E-71 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Gene3D G3DSA:3.10.600.10 459 1037 3.8E-232 T 14-10-2018 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 SUPERFAMILY SSF51230 1046 1123 2.62E-16 T 14-10-2018 IPR011053 Single hybrid motif A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1123 0.0 T 14-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 SUPERFAMILY SSF89000 824 989 2.43E-41 T 14-10-2018 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Pfam PF00364 Biotin-requiring enzyme 1064 1122 9.8E-14 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Pfam PF02436 Conserved carboxylase domain 819 1006 7.3E-56 T 14-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 SMART SM00878 339 446 5.1E-53 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.5E-39 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_38260 85219f5bdbc46a2abf82ac7387bf25db 1123 SUPERFAMILY SSF51569 517 827 2.2E-75 T 14-10-2018 A4R43_08475 b9ee79dc6406ddb20313455cc0ba58dd 421 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 176 1.2E-15 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_08475 b9ee79dc6406ddb20313455cc0ba58dd 421 Pfam PF04542 Sigma-70 region 2 30 89 5.7E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08475 b9ee79dc6406ddb20313455cc0ba58dd 421 Gene3D G3DSA:1.10.1740.10 10 86 9.0E-10 T 14-10-2018 A4R43_08475 b9ee79dc6406ddb20313455cc0ba58dd 421 Gene3D G3DSA:1.10.10.10 106 177 2.4E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08475 b9ee79dc6406ddb20313455cc0ba58dd 421 SUPERFAMILY SSF88659 116 175 6.73E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_08475 b9ee79dc6406ddb20313455cc0ba58dd 421 Pfam PF08281 Sigma-70, region 4 122 173 1.0E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_08475 b9ee79dc6406ddb20313455cc0ba58dd 421 SUPERFAMILY SSF88946 18 102 1.61E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_35720 dd4ce882e398e55196e5aae9e9ba0c9c 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 273 4.4E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_35720 dd4ce882e398e55196e5aae9e9ba0c9c 280 SUPERFAMILY SSF161098 13 280 2.35E-73 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_35720 dd4ce882e398e55196e5aae9e9ba0c9c 280 Gene3D G3DSA:1.10.3720.10 11 271 3.1E-65 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_15995 b682401d1c669741284b0015a85d5069 378 SUPERFAMILY SSF56645 3 239 2.62E-68 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_15995 b682401d1c669741284b0015a85d5069 378 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 214 7.4E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_15995 b682401d1c669741284b0015a85d5069 378 SUPERFAMILY SSF47203 228 372 1.27E-18 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_15995 b682401d1c669741284b0015a85d5069 378 Gene3D G3DSA:1.10.540.10 1 116 6.7E-27 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_15995 b682401d1c669741284b0015a85d5069 378 Gene3D G3DSA:1.20.140.10 233 377 1.1E-30 T 14-10-2018 A4R43_15995 b682401d1c669741284b0015a85d5069 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 370 1.2E-23 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_15995 b682401d1c669741284b0015a85d5069 378 Gene3D G3DSA:2.40.110.10 122 232 6.0E-37 T 14-10-2018 A4R43_15995 b682401d1c669741284b0015a85d5069 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 115 2.0E-19 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_41650 d52c4e80739f12ad87484a1672e0e698 137 Pfam PF12728 Helix-turn-helix domain 5 49 2.8E-16 T 14-10-2018 A4R43_41650 d52c4e80739f12ad87484a1672e0e698 137 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 49 1.3E-15 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A4R43_41650 d52c4e80739f12ad87484a1672e0e698 137 SUPERFAMILY SSF46955 5 51 3.39E-10 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_41650 d52c4e80739f12ad87484a1672e0e698 137 Gene3D G3DSA:1.10.1660.10 2 56 9.4E-15 T 14-10-2018 A4R43_03740 c4d327f24ee547f7a09913aaffd704df 489 Gene3D G3DSA:1.20.1740.10 22 477 4.5E-46 T 14-10-2018 A4R43_03740 c4d327f24ee547f7a09913aaffd704df 489 Pfam PF13520 Amino acid permease 27 451 2.8E-48 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_03740 c4d327f24ee547f7a09913aaffd704df 489 PIRSF PIRSF006060 6 483 3.7E-65 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 786 826 0.0016 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 741 780 0.0032 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 699 738 3.6E-6 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 1140 1179 0.0094 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 967 1000 55.0 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 614 651 76.0 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 832 871 9.5E-4 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 1007 1045 62.0 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 658 693 0.82 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 1185 1224 0.41 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 913 951 120.0 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 1096 1135 0.022 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 874 911 83.0 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SMART SM00320 1051 1090 0.0022 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SUPERFAMILY SSF52540 130 312 3.78E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 680 694 - T 14-10-2018 IPR019775 WD40 repeat, conserved site A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Gene3D G3DSA:2.130.10.10 749 964 1.5E-36 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SUPERFAMILY SSF50998 630 913 1.41E-49 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1166 1180 - T 14-10-2018 IPR019775 WD40 repeat, conserved site A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Gene3D G3DSA:2.130.10.10 1101 1248 6.6E-23 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Gene3D G3DSA:2.130.10.10 965 1100 3.2E-22 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 813 827 - T 14-10-2018 IPR019775 WD40 repeat, conserved site A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Gene3D G3DSA:2.130.10.10 609 748 4.7E-25 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Pfam PF00400 WD domain, G-beta repeat 1200 1223 0.028 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Pfam PF00400 WD domain, G-beta repeat 1110 1135 0.11 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Pfam PF00400 WD domain, G-beta repeat 793 826 0.0028 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Pfam PF00400 WD domain, G-beta repeat 711 738 0.0022 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Pfam PF00400 WD domain, G-beta repeat 1067 1090 0.14 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 Pfam PF00400 WD domain, G-beta repeat 748 776 0.0044 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 725 739 - T 14-10-2018 IPR019775 WD40 repeat, conserved site A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1122 1136 - T 14-10-2018 IPR019775 WD40 repeat, conserved site A4R43_04255 294b96350882b02b2f6fbcda9c1ebc72 1262 SUPERFAMILY SSF50978 922 1228 1.87E-46 T 14-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 A4R43_38520 8c242a55d29e95f7610e7675e0c5e6d4 289 Gene3D G3DSA:3.30.420.40 112 265 1.7E-53 T 14-10-2018 A4R43_38520 8c242a55d29e95f7610e7675e0c5e6d4 289 Gene3D G3DSA:3.30.420.40 4 277 1.7E-53 T 14-10-2018 A4R43_38520 8c242a55d29e95f7610e7675e0c5e6d4 289 SUPERFAMILY SSF53067 4 284 4.75E-41 T 14-10-2018 A4R43_38520 8c242a55d29e95f7610e7675e0c5e6d4 289 Pfam PF00480 ROK family 4 282 8.4E-42 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_23075 655abdfd04d8817779ca19b7ede1fc97 234 Gene3D G3DSA:1.10.3720.10 15 213 1.9E-26 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23075 655abdfd04d8817779ca19b7ede1fc97 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 210 1.3E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_23075 655abdfd04d8817779ca19b7ede1fc97 234 SUPERFAMILY SSF161098 20 205 1.74E-28 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 Gene3D G3DSA:3.90.20.20 53 152 1.6E-17 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 SUPERFAMILY SSF51064 155 211 1.06E-15 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 SUPERFAMILY SSF58014 67 154 3.4E-18 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 Hamap MF_01151 Protein GrpE [grpE]. 7 210 17.283 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 Pfam PF01025 GrpE 71 209 2.1E-34 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 ProSitePatterns PS01071 grpE protein signature. 165 208 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 Gene3D G3DSA:2.30.22.10 154 216 8.7E-18 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 PRINTS PR00773 GrpE protein signature 115 130 3.6E-24 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 PRINTS PR00773 GrpE protein signature 87 103 3.6E-24 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 PRINTS PR00773 GrpE protein signature 162 177 3.6E-24 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_31400 fc1a389bc9f3a647225e07f3a176d46c 247 PRINTS PR00773 GrpE protein signature 189 208 3.6E-24 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 Pfam PF13180 PDZ domain 437 509 4.7E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 SUPERFAMILY SSF50156 397 502 2.37E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 Gene3D G3DSA:2.40.10.10 207 301 1.9E-28 T 14-10-2018 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 SMART SM00228 426 500 8.3E-10 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 PRINTS PR00834 HtrA/DegQ protease family signature 314 338 5.4E-46 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 PRINTS PR00834 HtrA/DegQ protease family signature 355 372 5.4E-46 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 PRINTS PR00834 HtrA/DegQ protease family signature 458 470 5.4E-46 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 PRINTS PR00834 HtrA/DegQ protease family signature 274 294 5.4E-46 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 PRINTS PR00834 HtrA/DegQ protease family signature 377 394 5.4E-46 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 PRINTS PR00834 HtrA/DegQ protease family signature 248 260 5.4E-46 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 Pfam PF13365 Trypsin-like peptidase domain 239 384 2.4E-32 T 14-10-2018 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 Gene3D G3DSA:2.30.42.10 424 512 2.0E-22 T 14-10-2018 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 Gene3D G3DSA:2.40.10.10 305 423 3.7E-39 T 14-10-2018 A4R43_35665 4e1d28b1abf58334b7b3b678ed368e5a 512 SUPERFAMILY SSF50494 213 421 1.97E-53 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_25295 77cd008551d9393afedac550e89071e6 192 Gene3D G3DSA:3.40.50.850 1 191 3.7E-43 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_25295 77cd008551d9393afedac550e89071e6 192 SUPERFAMILY SSF52499 1 182 1.31E-37 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_25295 77cd008551d9393afedac550e89071e6 192 Pfam PF00857 Isochorismatase family 1 146 4.0E-33 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4R43_30810 163509536c289f41a759837d0a4091a0 352 SUPERFAMILY SSF51735 4 158 1.15E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_30810 163509536c289f41a759837d0a4091a0 352 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 236 1.3E-11 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A4R43_30810 163509536c289f41a759837d0a4091a0 352 SUPERFAMILY SSF55347 130 284 2.29E-28 T 14-10-2018 A4R43_30810 163509536c289f41a759837d0a4091a0 352 Gene3D G3DSA:3.40.50.720 6 318 1.1E-115 T 14-10-2018 A4R43_30810 163509536c289f41a759837d0a4091a0 352 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 3.7E-22 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_30810 163509536c289f41a759837d0a4091a0 352 Gene3D G3DSA:3.30.360.10 128 338 1.1E-115 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 238 288 1.2E-13 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Gene3D G3DSA:2.20.25.90 238 290 1.4E-15 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 SMART SM00929 101 141 2.0E-16 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Gene3D G3DSA:3.30.70.20 146 228 1.4E-22 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Gene3D G3DSA:2.40.40.20 804 917 5.7E-31 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 210 221 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Gene3D G3DSA:3.40.228.10 374 579 1.9E-171 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Pfam PF00384 Molybdopterin oxidoreductase 294 723 1.0E-76 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Pfam PF01568 Molydopterin dinucleotide binding domain 807 911 3.4E-24 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Gene3D G3DSA:3.10.20.740 19 140 7.3E-39 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 PIRSF PIRSF036643 16 921 0.0 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 845 872 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 SUPERFAMILY SSF53706 235 803 3.93E-191 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 SMART SM00926 237 291 3.2E-15 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Pfam PF13187 4Fe-4S dicluster domain 166 223 2.6E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Gene3D G3DSA:3.40.50.740 299 766 1.9E-171 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 101 140 1.3E-15 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 SUPERFAMILY SSF50692 775 915 1.33E-38 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 19 95 9.2E-24 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 242 915 3.3E-277 T 14-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 SUPERFAMILY SSF54862 93 233 2.76E-37 T 14-10-2018 A4R43_05855 6e2f409c55ea748b1c142d78a18e2ba0 926 SUPERFAMILY SSF54292 19 92 1.71E-17 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_20615 cd1016de41b88ae1885aa77ef3f12659 413 SUPERFAMILY SSF53720 8 399 3.53E-57 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_20615 cd1016de41b88ae1885aa77ef3f12659 413 Gene3D G3DSA:3.40.605.10 15 401 3.6E-101 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_20615 cd1016de41b88ae1885aa77ef3f12659 413 Gene3D G3DSA:3.40.309.10 233 372 3.6E-101 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_20615 cd1016de41b88ae1885aa77ef3f12659 413 PIRSF PIRSF000151 1 412 1.1E-74 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A4R43_20615 cd1016de41b88ae1885aa77ef3f12659 413 Pfam PF00171 Aldehyde dehydrogenase family 6 282 4.3E-14 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 SMART SM01134 72 242 1.1E-61 T 14-10-2018 A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.1E-7 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.1E-7 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 5.8E-15 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 SUPERFAMILY SSF46785 4 74 2.6E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 Pfam PF00455 DeoR C terminal sensor domain 75 240 1.7E-47 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 SMART SM00420 6 58 2.6E-12 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 SUPERFAMILY SSF100950 76 243 2.09E-28 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_09095 678236b71aa95d3cb0599ee8e91181c0 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 SUPERFAMILY SSF69864 190 438 1.44E-74 T 14-10-2018 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 Gene3D G3DSA:3.90.1260.10 74 367 3.9E-114 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 Gene3D G3DSA:1.10.287.400 377 440 1.1E-27 T 14-10-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 472 78.561 T 14-10-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 Gene3D G3DSA:3.40.50.620 14 191 3.9E-114 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 SUPERFAMILY SSF52402 4 185 1.02E-31 T 14-10-2018 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 5.5E-138 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 Pfam PF00764 Arginosuccinate synthase 16 393 9.2E-56 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4R43_40110 becc022f50c90f5f7242630ad629e39d 481 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4R43_19865 b11ab8c48fa23359018a4c5cce35d27d 323 SUPERFAMILY SSF46785 2 57 2.32E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19865 b11ab8c48fa23359018a4c5cce35d27d 323 Pfam PF13280 WYL domain 146 316 1.9E-30 T 14-10-2018 IPR026881 WYL domain A4R43_19865 b11ab8c48fa23359018a4c5cce35d27d 323 PIRSF PIRSF016838 72 323 1.6E-14 T 14-10-2018 IPR028349 Protein PafC A4R43_19865 b11ab8c48fa23359018a4c5cce35d27d 323 PIRSF PIRSF016838 1 52 0.0019 T 14-10-2018 IPR028349 Protein PafC A4R43_19865 b11ab8c48fa23359018a4c5cce35d27d 323 Pfam PF08279 HTH domain 10 57 6.1E-15 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_19865 b11ab8c48fa23359018a4c5cce35d27d 323 Gene3D G3DSA:1.10.10.10 1 62 4.4E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41215 dc1ee450c59e63c1c6ec3ac349fecd7f 177 Gene3D G3DSA:1.20.5.780 109 151 7.2E-5 T 14-10-2018 A4R43_41215 dc1ee450c59e63c1c6ec3ac349fecd7f 177 SUPERFAMILY SSF47598 110 154 2.32E-8 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4R43_41215 dc1ee450c59e63c1c6ec3ac349fecd7f 177 Pfam PF05534 HicB family 98 145 3.8E-7 T 14-10-2018 IPR008651 Uncharacterised protein family HicB A4R43_27270 be09d6ab753aadd03aecf6f5b87d25f0 255 Pfam PF08241 Methyltransferase domain 40 135 4.8E-17 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_27270 be09d6ab753aadd03aecf6f5b87d25f0 255 Gene3D G3DSA:3.40.50.150 15 213 2.1E-30 T 14-10-2018 A4R43_27270 be09d6ab753aadd03aecf6f5b87d25f0 255 SUPERFAMILY SSF53335 20 196 1.03E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_25640 3c668cff404e679e2e45347e01f59c90 206 SUPERFAMILY SSF46689 2 68 1.5E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25640 3c668cff404e679e2e45347e01f59c90 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 52 1.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25640 3c668cff404e679e2e45347e01f59c90 206 Gene3D G3DSA:1.10.357.10 1 199 7.3E-56 T 14-10-2018 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 179 195 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 SMART SM00478 30 177 7.4E-55 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 Gene3D G3DSA:1.10.340.30 13 124 4.3E-72 T 14-10-2018 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 Hamap MF_00942 Endonuclease III [nth]. 1 201 35.982 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 ProSitePatterns PS01155 Endonuclease III family signature. 94 123 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 TIGRFAM TIGR01083 nth: endonuclease III 4 186 9.0E-78 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 PIRSF PIRSF001435 3 204 1.4E-44 T 14-10-2018 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 179 195 4.2E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 160 4.3E-19 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 Gene3D G3DSA:1.10.1670.10 5 195 4.3E-72 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 SUPERFAMILY SSF48150 5 199 2.98E-65 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 Pfam PF00633 Helix-hairpin-helix motif 91 118 5.8E-7 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A4R43_27160 4a8dadf2e7170ef3a30fa26af1024a2d 227 SMART SM00525 178 198 3.5E-6 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 Pfam PF00931 NB-ARC domain 37 281 1.6E-13 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 SUPERFAMILY SSF48452 484 661 2.53E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 Gene3D G3DSA:3.40.50.300 14 170 1.5E-27 T 14-10-2018 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 PRINTS PR00364 Disease resistance protein signature 217 231 1.3E-8 T 14-10-2018 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 PRINTS PR00364 Disease resistance protein signature 51 66 1.3E-8 T 14-10-2018 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 PRINTS PR00364 Disease resistance protein signature 129 143 1.3E-8 T 14-10-2018 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 SUPERFAMILY SSF52540 23 282 1.6E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 Gene3D G3DSA:1.25.40.10 425 582 1.2E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 SMART SM00028 628 661 37.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 SMART SM00028 468 501 30.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 SMART SM00028 508 541 22.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 SMART SM00028 588 621 210.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 SMART SM00028 548 581 150.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 Gene3D G3DSA:1.25.40.10 583 675 3.2E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 Pfam PF13424 Tetratricopeptide repeat 547 619 9.7E-8 T 14-10-2018 A4R43_28910 d5dc8b380934c8b8e946199dba694a83 677 Pfam PF13424 Tetratricopeptide repeat 468 539 2.5E-10 T 14-10-2018 A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 Gene3D G3DSA:1.10.1660.10 2 114 2.7E-21 T 14-10-2018 A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 Pfam PF13411 MerR HTH family regulatory protein 6 72 5.2E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 Gene3D G3DSA:3.20.80.10 115 265 1.5E-31 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 Pfam PF06445 GyrI-like small molecule binding domain 147 262 2.6E-13 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 SMART SM00422 4 74 1.4E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 SUPERFAMILY SSF46955 4 100 1.06E-19 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 SMART SM00871 111 263 8.2E-7 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding A4R43_39445 75672bec65351667af8d8dc1ab2f3a4f 265 SUPERFAMILY SSF55136 193 262 2.79E-15 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A4R43_20400 9ea9a89c87cffa72741cb8fb64a82c38 362 SMART SM00387 270 360 3.4E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_20400 9ea9a89c87cffa72741cb8fb64a82c38 362 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 316 1.9E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_20400 9ea9a89c87cffa72741cb8fb64a82c38 362 Pfam PF07730 Histidine kinase 165 230 1.5E-21 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_20400 9ea9a89c87cffa72741cb8fb64a82c38 362 SUPERFAMILY SSF55874 271 359 2.33E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_20400 9ea9a89c87cffa72741cb8fb64a82c38 362 Gene3D G3DSA:3.30.565.10 241 358 2.0E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25270 b7083b18f0f6b08a468f00118a619f6b 294 SUPERFAMILY SSF53474 7 273 1.75E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25270 b7083b18f0f6b08a468f00118a619f6b 294 Gene3D G3DSA:3.40.50.1820 1 287 4.2E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25270 b7083b18f0f6b08a468f00118a619f6b 294 Pfam PF00561 alpha/beta hydrolase fold 24 269 3.3E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_01460 1135356d092fd62f644358d5b8a036cd 180 Pfam PF00691 OmpA family 87 171 2.7E-14 T 14-10-2018 IPR006665 OmpA-like domain A4R43_01460 1135356d092fd62f644358d5b8a036cd 180 SUPERFAMILY SSF103088 83 167 5.36E-11 T 14-10-2018 IPR036737 OmpA-like domain superfamily A4R43_01460 1135356d092fd62f644358d5b8a036cd 180 Gene3D G3DSA:3.30.1330.60 62 175 1.7E-12 T 14-10-2018 IPR036737 OmpA-like domain superfamily A4R43_02030 c1a1537dc33ae5b15a40db62903cbc39 162 Pfam PF03737 Aldolase/RraA 9 157 7.2E-41 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A4R43_02030 c1a1537dc33ae5b15a40db62903cbc39 162 TIGRFAM TIGR01935 NOT-MenG: RraA family 9 157 2.4E-60 T 14-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 A4R43_02030 c1a1537dc33ae5b15a40db62903cbc39 162 Gene3D G3DSA:3.50.30.40 4 162 8.5E-58 T 14-10-2018 A4R43_02030 c1a1537dc33ae5b15a40db62903cbc39 162 SUPERFAMILY SSF89562 9 160 2.35E-45 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily A4R43_22750 9538302e70219acf4e09219274f3310e 287 Gene3D G3DSA:3.60.15.10 1 287 3.1E-64 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_22750 9538302e70219acf4e09219274f3310e 287 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 287 82.58 T 14-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B A4R43_22750 9538302e70219acf4e09219274f3310e 287 Pfam PF12706 Beta-lactamase superfamily domain 45 253 2.6E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_22750 9538302e70219acf4e09219274f3310e 287 SUPERFAMILY SSF56281 1 286 7.22E-35 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_10435 3da72fcd11a016cb5662399513fa955d 431 Pfam PF07690 Major Facilitator Superfamily 18 379 1.7E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_10435 3da72fcd11a016cb5662399513fa955d 431 Gene3D G3DSA:1.20.1250.20 3 418 5.7E-67 T 14-10-2018 A4R43_10435 3da72fcd11a016cb5662399513fa955d 431 SUPERFAMILY SSF103473 3 420 5.62E-79 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Pfam PF08990 Erythronolide synthase docking 3 27 1.5E-13 T 14-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Gene3D G3DSA:3.40.50.1820 1452 1723 5.2E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SUPERFAMILY SSF55048 655 716 7.06E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Gene3D G3DSA:3.40.50.720 886 1344 4.6E-129 T 14-10-2018 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1388 1403 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Pfam PF00550 Phosphopantetheine attachment site 1371 1429 6.3E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Gene3D G3DSA:1.10.1200.10 1345 1436 3.2E-27 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SMART SM00825 Beta-ketoacyl synthase 36 457 3.3E-213 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 407 519 3.4E-16 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SUPERFAMILY SSF52151 535 805 7.32E-71 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SMART SM00823 Phosphopantetheine attachment site 1361 1433 7.2E-23 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Gene3D G3DSA:3.30.70.3290 477 865 1.3E-147 T 14-10-2018 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Gene3D G3DSA:3.40.47.10 25 476 2.8E-182 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SUPERFAMILY SSF51735 1080 1311 1.47E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Gene3D G3DSA:3.40.366.10 536 821 1.3E-147 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1082 1262 9.5E-63 T 14-10-2018 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Pfam PF08659 KR domain 1082 1260 1.2E-60 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SUPERFAMILY SSF53901 30 395 3.52E-100 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SMART SM00824 Thioesterase 1510 1721 1.2E-62 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SUPERFAMILY SSF53474 1391 1721 1.12E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 281 9.0E-88 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 538 818 5.5E-120 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 404 2.2E-42 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Pfam PF00698 Acyl transferase domain 538 837 9.7E-56 T 14-10-2018 IPR014043 Acyl transferase A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SMART SM01294 1361 1429 0.0011 T 14-10-2018 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 Pfam PF00975 Thioesterase domain 1514 1610 2.4E-13 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_38460 bdff5b40cc2823ab4c464d86e9b8f9a4 1724 SUPERFAMILY SSF51735 886 1068 8.56E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_21620 cefbdc61e530e9332673e56ae90bd850 388 Pfam PF01609 Transposase DDE domain 127 342 1.6E-14 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4R43_21620 cefbdc61e530e9332673e56ae90bd850 388 SUPERFAMILY SSF53098 90 350 8.34E-22 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_21620 cefbdc61e530e9332673e56ae90bd850 388 Pfam PF13006 Insertion element 4 transposase N-terminal 11 103 2.5E-22 T 14-10-2018 IPR024473 Transposase, IS4, N-terminal A4R43_18590 cefbdc61e530e9332673e56ae90bd850 388 Pfam PF01609 Transposase DDE domain 127 342 1.6E-14 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4R43_18590 cefbdc61e530e9332673e56ae90bd850 388 SUPERFAMILY SSF53098 90 350 8.34E-22 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_18590 cefbdc61e530e9332673e56ae90bd850 388 Pfam PF13006 Insertion element 4 transposase N-terminal 11 103 2.5E-22 T 14-10-2018 IPR024473 Transposase, IS4, N-terminal A4R43_38165 241c282e0f8aa26604bc33ad980fae88 344 Pfam PF13407 Periplasmic binding protein domain 41 299 9.0E-44 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_38165 241c282e0f8aa26604bc33ad980fae88 344 Gene3D G3DSA:3.40.50.2300 138 342 6.6E-71 T 14-10-2018 A4R43_38165 241c282e0f8aa26604bc33ad980fae88 344 SUPERFAMILY SSF53822 39 336 1.41E-53 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_38165 241c282e0f8aa26604bc33ad980fae88 344 Gene3D G3DSA:3.40.50.2300 47 324 6.6E-71 T 14-10-2018 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 Gene3D G3DSA:3.40.50.10860 10 345 3.4E-132 T 14-10-2018 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 SUPERFAMILY SSF53223 10 144 2.46E-44 T 14-10-2018 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 3.7E-19 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 3.7E-19 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 3.7E-19 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 288 299 3.7E-19 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 SMART SM00839 144 353 1.2E-44 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 Gene3D G3DSA:3.40.50.720 134 338 3.4E-132 T 14-10-2018 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 PIRSF PIRSF000188 5 355 2.6E-141 T 14-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 215 299 1.9E-10 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 13 131 6.2E-26 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A4R43_38030 d1140377aebae32f5b4de0e69d1e4300 357 SUPERFAMILY SSF51735 141 349 6.64E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 173 3.5E-19 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 213 3.5E-19 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 PRINTS PR00723 Subtilisin serine protease family (S8) signature 383 399 3.5E-19 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 159 170 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 204 214 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 Pfam PF00082 Subtilase family 157 431 6.9E-38 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 SUPERFAMILY SSF52743 142 460 4.71E-62 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 384 394 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_39245 7bceb16b512c6d91c98b2f363d06ed8a 464 Gene3D G3DSA:3.40.50.200 77 463 4.3E-70 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 7 734 29.049 T 14-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Pfam PF14520 Helix-hairpin-helix domain 96 145 7.0E-7 T 14-10-2018 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 SUPERFAMILY SSF52540 186 493 4.27E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 SUPERFAMILY SSF52540 444 718 1.24E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Pfam PF13604 AAA domain 335 513 4.0E-43 T 14-10-2018 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Gene3D G3DSA:3.40.50.300 493 721 1.3E-142 T 14-10-2018 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Pfam PF13538 UvrD-like helicase C-terminal domain 657 705 5.0E-20 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 SMART SM00278 188 207 250.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 SMART SM00278 96 110 200.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 SMART SM00278 124 143 95.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Gene3D G3DSA:2.30.30.940 581 658 1.3E-142 T 14-10-2018 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 SUPERFAMILY SSF47781 88 164 6.18E-11 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Pfam PF14490 Helix-hairpin-helix containing domain 146 236 6.7E-32 T 14-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Gene3D G3DSA:3.40.50.300 326 727 1.3E-142 T 14-10-2018 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Gene3D G3DSA:1.10.10.2220 189 281 8.1E-24 T 14-10-2018 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 SMART SM00382 348 530 0.0064 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 12 731 1.2E-207 T 14-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A4R43_37615 7411228ae6b8deaad93ece8df3f141ea 734 Gene3D G3DSA:1.10.150.20 80 149 7.9E-10 T 14-10-2018 A4R43_17540 fc305a11c0483c5719248dda18d29372 108 SUPERFAMILY SSF89095 3 106 6.28E-10 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A4R43_17540 fc305a11c0483c5719248dda18d29372 108 Pfam PF09424 Yqey-like protein 3 107 1.1E-14 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 A4R43_17540 fc305a11c0483c5719248dda18d29372 108 Gene3D G3DSA:1.10.1510.10 1 105 5.5E-16 T 14-10-2018 A4R43_38625 1d85c1cc00dcae6b8f58175ec30e0fb7 681 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 248 6.8E-86 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_38625 1d85c1cc00dcae6b8f58175ec30e0fb7 681 SUPERFAMILY SSF52151 543 581 1.67E-7 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_38625 1d85c1cc00dcae6b8f58175ec30e0fb7 681 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 380 479 6.6E-16 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38625 1d85c1cc00dcae6b8f58175ec30e0fb7 681 SUPERFAMILY SSF53901 5 412 5.93E-89 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38625 1d85c1cc00dcae6b8f58175ec30e0fb7 681 Gene3D G3DSA:3.40.47.10 2 495 6.6E-176 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_38625 1d85c1cc00dcae6b8f58175ec30e0fb7 681 SMART SM00825 Beta-ketoacyl synthase 5 418 4.3E-150 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_38625 1d85c1cc00dcae6b8f58175ec30e0fb7 681 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 367 1.7E-36 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_38625 1d85c1cc00dcae6b8f58175ec30e0fb7 681 Gene3D G3DSA:3.40.366.20 527 582 3.1E-10 T 14-10-2018 A4R43_34125 424712e1cc98759a26d6844d149879ea 553 SUPERFAMILY SSF56801 22 552 1.23E-105 T 14-10-2018 A4R43_34125 424712e1cc98759a26d6844d149879ea 553 Gene3D G3DSA:3.40.50.12780 9 442 9.7E-143 T 14-10-2018 A4R43_34125 424712e1cc98759a26d6844d149879ea 553 Pfam PF00501 AMP-binding enzyme 23 448 4.7E-81 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_34125 424712e1cc98759a26d6844d149879ea 553 Gene3D G3DSA:3.30.300.30 443 553 1.6E-33 T 14-10-2018 A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 Gene3D G3DSA:1.10.10.10 1 85 1.8E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 Pfam PF03466 LysR substrate binding domain 88 293 4.4E-38 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 Gene3D G3DSA:3.40.190.10 163 268 4.9E-57 T 14-10-2018 A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.1E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 Gene3D G3DSA:3.40.190.10 88 286 4.9E-57 T 14-10-2018 A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 SUPERFAMILY SSF53850 91 296 5.84E-35 T 14-10-2018 A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21310 b2b3e054908935b3053f308328e3cdd5 299 SUPERFAMILY SSF46785 1 84 9.09E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04235 40741147aba51b3de548b9b6e091326d 683 Pfam PF13424 Tetratricopeptide repeat 551 622 5.4E-12 T 14-10-2018 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 Pfam PF13424 Tetratricopeptide repeat 470 541 3.6E-11 T 14-10-2018 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 Gene3D G3DSA:3.40.50.300 2 177 1.0E-27 T 14-10-2018 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 Pfam PF00931 NB-ARC domain 48 277 2.6E-9 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 SUPERFAMILY SSF52540 9 282 8.22E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04235 40741147aba51b3de548b9b6e091326d 683 PRINTS PR00364 Disease resistance protein signature 48 63 1.8E-7 T 14-10-2018 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 PRINTS PR00364 Disease resistance protein signature 126 140 1.8E-7 T 14-10-2018 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 PRINTS PR00364 Disease resistance protein signature 214 228 1.8E-7 T 14-10-2018 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 SMART SM00028 510 543 1.8 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 SMART SM00028 630 663 16.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 SMART SM00028 590 623 0.021 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 SMART SM00028 470 503 5.7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 SMART SM00028 550 583 0.81 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 Gene3D G3DSA:1.25.40.10 393 676 5.3E-52 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_04235 40741147aba51b3de548b9b6e091326d 683 SUPERFAMILY SSF48452 462 671 2.09E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03825 67756bfcac82b050be64e7f1a08d308b 468 SUPERFAMILY SSF50443 319 464 1.36E-24 T 14-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal A4R43_03825 67756bfcac82b050be64e7f1a08d308b 468 SUPERFAMILY SSF53743 3 322 4.32E-65 T 14-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A4R43_03825 67756bfcac82b050be64e7f1a08d308b 468 Gene3D G3DSA:3.40.50.10940 19 169 3.1E-5 T 14-10-2018 IPR038583 L-arabinose isomerase, N-terminal domain superfamily KEGG: 00040+5.3.1.4 A4R43_03825 67756bfcac82b050be64e7f1a08d308b 468 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 2 294 3.0E-6 T 14-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 A4R43_03825 67756bfcac82b050be64e7f1a08d308b 468 Pfam PF02610 L-arabinose isomerase 20 331 2.5E-15 T 14-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 A4R43_29065 e804fe62bb9ede84bd9d8baade3afdd2 316 SUPERFAMILY SSF52266 29 287 1.12E-58 T 14-10-2018 A4R43_29065 e804fe62bb9ede84bd9d8baade3afdd2 316 Gene3D G3DSA:3.40.50.1110 28 288 1.4E-68 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_29065 e804fe62bb9ede84bd9d8baade3afdd2 316 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 33 276 5.9E-27 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_21005 f0e6b4bafcca523886d8b0bae4daf141 838 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 519 624 6.7E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_21005 f0e6b4bafcca523886d8b0bae4daf141 838 SUPERFAMILY SSF55874 505 629 3.27E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_21005 f0e6b4bafcca523886d8b0bae4daf141 838 Pfam PF00672 HAMP domain 336 399 1.7E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_21005 f0e6b4bafcca523886d8b0bae4daf141 838 Pfam PF08376 Nitrate and nitrite sensing 65 280 1.8E-26 T 14-10-2018 IPR013587 Nitrate/nitrite sensing protein A4R43_21005 f0e6b4bafcca523886d8b0bae4daf141 838 Gene3D G3DSA:3.30.565.10 505 629 9.9E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_21005 f0e6b4bafcca523886d8b0bae4daf141 838 SMART SM00387 516 629 5.0E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_02985 9c000d327cdfc2e577f3843fcc2341ec 367 Pfam PF13378 Enolase C-terminal domain-like 143 358 1.3E-40 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_02985 9c000d327cdfc2e577f3843fcc2341ec 367 SUPERFAMILY SSF54826 1 124 1.3E-33 T 14-10-2018 A4R43_02985 9c000d327cdfc2e577f3843fcc2341ec 367 Gene3D G3DSA:3.20.20.120 120 367 3.1E-65 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_02985 9c000d327cdfc2e577f3843fcc2341ec 367 SUPERFAMILY SSF51604 122 363 4.63E-58 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_02985 9c000d327cdfc2e577f3843fcc2341ec 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 123 2.0E-17 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_02985 9c000d327cdfc2e577f3843fcc2341ec 367 SMART SM00922 140 238 2.0E-25 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_02985 9c000d327cdfc2e577f3843fcc2341ec 367 Gene3D G3DSA:3.30.390.10 1 119 2.1E-35 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_38600 8037f33bcc851b5c0260f9d33307a0e7 271 Pfam PF01061 ABC-2 type transporter 25 233 1.6E-29 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_38600 8037f33bcc851b5c0260f9d33307a0e7 271 PIRSF PIRSF006648 1 270 1.3E-74 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 SMART SM00382 31 214 7.9E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 SUPERFAMILY SSF50331 239 353 2.92E-24 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 Pfam PF08402 TOBE domain 275 342 5.7E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 Pfam PF00005 ABC transporter 23 164 1.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 Gene3D G3DSA:3.40.50.300 9 224 8.9E-58 T 14-10-2018 A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 SUPERFAMILY SSF52540 12 245 2.24E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 Gene3D G3DSA:2.40.50.140 281 336 2.0E-26 T 14-10-2018 A4R43_11465 d642cc7cc656302fb3e85373668e0b3c 355 Gene3D G3DSA:2.40.50.940 225 346 2.0E-26 T 14-10-2018 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 1.4E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 3.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 3.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 3.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 SMART SM00421 151 208 4.1E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 Pfam PF00072 Response regulator receiver domain 4 115 2.9E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 SUPERFAMILY SSF46894 139 214 6.12E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 Gene3D G3DSA:3.40.50.12740 2 214 7.7E-71 T 14-10-2018 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 SMART SM00448 2 115 1.1E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_20405 65265ee045142a59d0330ffe9accbd60 218 SUPERFAMILY SSF52172 2 133 7.83E-34 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_01125 ca3affe23fa03981198ad91e96c01e3e 563 Pfam PF03354 Phage Terminase 89 548 3.5E-43 T 14-10-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type A4R43_01125 ca3affe23fa03981198ad91e96c01e3e 563 Gene3D G3DSA:3.40.50.300 37 246 9.7E-22 T 14-10-2018 A4R43_31595 bb507c2ff0585bbddcd34b733a130459 191 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 35 189 1.1E-46 T 14-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4R43_31595 bb507c2ff0585bbddcd34b733a130459 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 187 4.1E-25 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_31595 bb507c2ff0585bbddcd34b733a130459 191 SUPERFAMILY SSF88659 117 189 2.43E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_31595 bb507c2ff0585bbddcd34b733a130459 191 Gene3D G3DSA:1.10.10.10 132 189 4.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31595 bb507c2ff0585bbddcd34b733a130459 191 Pfam PF08281 Sigma-70, region 4 131 183 3.1E-18 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_31595 bb507c2ff0585bbddcd34b733a130459 191 Pfam PF04542 Sigma-70 region 2 38 104 5.1E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31595 bb507c2ff0585bbddcd34b733a130459 191 SUPERFAMILY SSF88946 35 110 1.1E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31595 bb507c2ff0585bbddcd34b733a130459 191 Gene3D G3DSA:1.10.1740.10 33 131 7.2E-12 T 14-10-2018 A4R43_28810 5ceb1fa6a9f1631bff894b0c91eaf40c 171 Pfam PF04542 Sigma-70 region 2 17 84 1.8E-10 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_28810 5ceb1fa6a9f1631bff894b0c91eaf40c 171 Gene3D G3DSA:1.10.1740.10 4 80 8.8E-11 T 14-10-2018 A4R43_28810 5ceb1fa6a9f1631bff894b0c91eaf40c 171 Pfam PF08281 Sigma-70, region 4 112 161 1.2E-7 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_28810 5ceb1fa6a9f1631bff894b0c91eaf40c 171 Gene3D G3DSA:1.10.10.10 85 170 4.3E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28810 5ceb1fa6a9f1631bff894b0c91eaf40c 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 164 1.2E-15 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_28810 5ceb1fa6a9f1631bff894b0c91eaf40c 171 SUPERFAMILY SSF88946 9 100 1.88E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_28810 5ceb1fa6a9f1631bff894b0c91eaf40c 171 SUPERFAMILY SSF88659 104 167 3.55E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_15905 8b1eff11399b3c400032c3e45b723eab 327 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 195 226 3.7E-8 T 14-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal A4R43_15905 8b1eff11399b3c400032c3e45b723eab 327 SUPERFAMILY SSF50249 5 136 2.91E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_15905 8b1eff11399b3c400032c3e45b723eab 327 SUPERFAMILY SSF50249 167 301 3.77E-36 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_15905 8b1eff11399b3c400032c3e45b723eab 327 Gene3D G3DSA:1.10.12.20 6 67 1.1E-5 T 14-10-2018 A4R43_15905 8b1eff11399b3c400032c3e45b723eab 327 Gene3D G3DSA:1.10.12.20 164 233 3.9E-15 T 14-10-2018 A4R43_15905 8b1eff11399b3c400032c3e45b723eab 327 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 65 128 5.9E-12 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A4R43_15905 8b1eff11399b3c400032c3e45b723eab 327 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 230 295 2.5E-13 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A4R43_14540 918e2eba84c46c8a422b44340fd4aba2 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 1.0E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_14540 918e2eba84c46c8a422b44340fd4aba2 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 1.0E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_14540 918e2eba84c46c8a422b44340fd4aba2 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 1.0E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_14540 918e2eba84c46c8a422b44340fd4aba2 106 Gene3D G3DSA:1.10.10.10 1 105 7.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14540 918e2eba84c46c8a422b44340fd4aba2 106 Pfam PF12840 Helix-turn-helix domain 5 65 1.2E-15 T 14-10-2018 A4R43_14540 918e2eba84c46c8a422b44340fd4aba2 106 SUPERFAMILY SSF46785 2 101 1.34E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14540 918e2eba84c46c8a422b44340fd4aba2 106 SMART SM00418 6 83 7.3E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_34415 772f415acfebaf486faafb17c3733002 517 Gene3D G3DSA:3.30.200.20 2 96 2.9E-27 T 14-10-2018 A4R43_34415 772f415acfebaf486faafb17c3733002 517 SUPERFAMILY SSF56112 4 268 1.75E-70 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_34415 772f415acfebaf486faafb17c3733002 517 Pfam PF00069 Protein kinase domain 12 264 1.1E-47 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_34415 772f415acfebaf486faafb17c3733002 517 PRINTS PR01217 Proline rich extensin signature 368 384 4.6E-10 T 14-10-2018 A4R43_34415 772f415acfebaf486faafb17c3733002 517 PRINTS PR01217 Proline rich extensin signature 433 454 4.6E-10 T 14-10-2018 A4R43_34415 772f415acfebaf486faafb17c3733002 517 PRINTS PR01217 Proline rich extensin signature 501 517 4.6E-10 T 14-10-2018 A4R43_34415 772f415acfebaf486faafb17c3733002 517 PRINTS PR01217 Proline rich extensin signature 461 477 4.6E-10 T 14-10-2018 A4R43_34415 772f415acfebaf486faafb17c3733002 517 PRINTS PR01217 Proline rich extensin signature 478 495 4.6E-10 T 14-10-2018 A4R43_34415 772f415acfebaf486faafb17c3733002 517 SMART SM00220 12 271 7.4E-61 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_34415 772f415acfebaf486faafb17c3733002 517 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_34415 772f415acfebaf486faafb17c3733002 517 Gene3D G3DSA:1.10.510.10 98 277 6.1E-44 T 14-10-2018 A4R43_34415 772f415acfebaf486faafb17c3733002 517 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_22795 53f6c02155414fe84de3a60e2abb4d30 489 Pfam PF00795 Carbon-nitrogen hydrolase 250 454 5.6E-16 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_22795 53f6c02155414fe84de3a60e2abb4d30 489 Gene3D G3DSA:3.60.110.10 234 463 7.2E-27 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_22795 53f6c02155414fe84de3a60e2abb4d30 489 SUPERFAMILY SSF56317 250 453 1.7E-33 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 SUPERFAMILY SSF52540 1008 1253 5.33E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 SUPERFAMILY SSF52540 343 586 8.91E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 Gene3D G3DSA:3.40.50.300 1005 1255 3.1E-83 T 14-10-2018 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 Pfam PF00005 ABC transporter 370 519 4.7E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 Gene3D G3DSA:3.40.50.300 351 599 8.2E-85 T 14-10-2018 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 SUPERFAMILY SSF90123 686 998 2.75E-72 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 Pfam PF00664 ABC transporter transmembrane region 40 307 6.4E-35 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 Pfam PF00664 ABC transporter transmembrane region 704 970 3.2E-34 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 Gene3D G3DSA:1.20.1560.10 10 340 3.1E-70 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 Gene3D G3DSA:1.20.1560.10 680 1001 1.2E-79 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 SUPERFAMILY SSF90123 19 342 3.66E-68 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 SMART SM00382 1044 1230 1.3E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 SMART SM00382 379 573 1.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 Pfam PF00005 ABC transporter 1035 1184 1.8E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23010 a6fe9e7811007eff371807fb8c4ad6ee 1255 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_25100 d5a91f71ceb731abfa182c0e41fca40b 1024 SUPERFAMILY SSF52540 626 993 6.0E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25100 d5a91f71ceb731abfa182c0e41fca40b 1024 Pfam PF01935 Domain of unknown function DUF87 628 870 9.5E-9 T 14-10-2018 IPR002789 Helicase HerA, central domain A4R43_25100 d5a91f71ceb731abfa182c0e41fca40b 1024 SMART SM00382 56 327 7.4 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_25100 d5a91f71ceb731abfa182c0e41fca40b 1024 SMART SM00382 637 947 0.087 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_25100 d5a91f71ceb731abfa182c0e41fca40b 1024 Gene3D G3DSA:3.40.50.300 831 1002 6.6E-20 T 14-10-2018 A4R43_25100 d5a91f71ceb731abfa182c0e41fca40b 1024 Gene3D G3DSA:3.40.50.300 600 720 2.9E-10 T 14-10-2018 A4R43_11290 a2c48d7f0a83ed8950458b0f23bd8359 289 Gene3D G3DSA:3.40.50.1820 9 268 3.9E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_11290 a2c48d7f0a83ed8950458b0f23bd8359 289 SUPERFAMILY SSF53474 22 284 1.34E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_11290 a2c48d7f0a83ed8950458b0f23bd8359 289 Pfam PF00561 alpha/beta hydrolase fold 47 182 1.1E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_11290 a2c48d7f0a83ed8950458b0f23bd8359 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 1.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_11290 a2c48d7f0a83ed8950458b0f23bd8359 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 231 245 1.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_11290 a2c48d7f0a83ed8950458b0f23bd8359 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 72 87 1.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_11290 a2c48d7f0a83ed8950458b0f23bd8359 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 1.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22725 e179fc369457bebcf3ab85023a450b75 456 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 7 264 1.4E-76 T 14-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_22725 e179fc369457bebcf3ab85023a450b75 456 Gene3D G3DSA:3.30.559.30 194 323 1.1E-6 T 14-10-2018 A4R43_22725 e179fc369457bebcf3ab85023a450b75 456 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 7 454 2.5E-149 T 14-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_22725 e179fc369457bebcf3ab85023a450b75 456 Gene3D G3DSA:3.30.559.10 42 193 1.1E-6 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_22725 e179fc369457bebcf3ab85023a450b75 456 SUPERFAMILY SSF52777 29 154 2.11E-6 T 14-10-2018 A4R43_22725 e179fc369457bebcf3ab85023a450b75 456 Pfam PF06974 Protein of unknown function (DUF1298) 306 451 1.7E-38 T 14-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_21610 02b19c4d272e2e6975629e80cb5d3f3c 259 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 3.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_21610 02b19c4d272e2e6975629e80cb5d3f3c 259 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 3.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_21610 02b19c4d272e2e6975629e80cb5d3f3c 259 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 3.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_21610 02b19c4d272e2e6975629e80cb5d3f3c 259 Pfam PF00376 MerR family regulatory protein 6 43 2.4E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_21610 02b19c4d272e2e6975629e80cb5d3f3c 259 SUPERFAMILY SSF46955 6 108 4.76E-24 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_21610 02b19c4d272e2e6975629e80cb5d3f3c 259 Gene3D G3DSA:1.10.1660.10 3 114 4.5E-24 T 14-10-2018 A4R43_21610 02b19c4d272e2e6975629e80cb5d3f3c 259 SMART SM00422 5 74 1.8E-22 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31635 26966239391e689f384fa43bd78dc053 407 Pfam PF03583 Secretory lipase 128 400 3.6E-67 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_31635 26966239391e689f384fa43bd78dc053 407 SUPERFAMILY SSF53474 71 368 2.5E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_31635 26966239391e689f384fa43bd78dc053 407 Gene3D G3DSA:1.10.260.130 233 323 3.4E-109 T 14-10-2018 A4R43_31635 26966239391e689f384fa43bd78dc053 407 Gene3D G3DSA:3.40.50.1820 32 394 3.4E-109 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_31635 26966239391e689f384fa43bd78dc053 407 PIRSF PIRSF029171 2 404 8.4E-82 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_39375 7545432993604b3dc25d567751bc566c 419 Gene3D G3DSA:3.40.50.1100 119 216 1.1E-101 T 14-10-2018 A4R43_39375 7545432993604b3dc25d567751bc566c 419 TIGRFAM TIGR00260 thrC: threonine synthase 65 393 6.7E-85 T 14-10-2018 IPR004450 Threonine synthase-like A4R43_39375 7545432993604b3dc25d567751bc566c 419 SUPERFAMILY SSF53686 17 416 5.37E-84 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_39375 7545432993604b3dc25d567751bc566c 419 Gene3D G3DSA:3.40.50.1100 67 392 1.1E-101 T 14-10-2018 A4R43_39375 7545432993604b3dc25d567751bc566c 419 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 87 387 4.9E-68 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_41665 3b60f49f62dcef53e61fc255aa6a04f7 245 Gene3D G3DSA:3.40.50.150 39 227 9.2E-42 T 14-10-2018 A4R43_41665 3b60f49f62dcef53e61fc255aa6a04f7 245 Gene3D G3DSA:2.20.25.110 147 202 9.2E-42 T 14-10-2018 A4R43_41665 3b60f49f62dcef53e61fc255aa6a04f7 245 SUPERFAMILY SSF53335 10 241 2.28E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_41665 3b60f49f62dcef53e61fc255aa6a04f7 245 Pfam PF13649 Methyltransferase domain 44 139 7.0E-19 T 14-10-2018 A4R43_24275 723a9d55dd1522c3225a7e3501117039 341 Gene3D G3DSA:3.40.50.2300 96 319 5.8E-30 T 14-10-2018 A4R43_24275 723a9d55dd1522c3225a7e3501117039 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 62 3.1E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_24275 723a9d55dd1522c3225a7e3501117039 341 SUPERFAMILY SSF47413 13 73 1.21E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_24275 723a9d55dd1522c3225a7e3501117039 341 Gene3D G3DSA:3.40.50.2300 168 295 5.8E-30 T 14-10-2018 A4R43_24275 723a9d55dd1522c3225a7e3501117039 341 Pfam PF13377 Periplasmic binding protein-like domain 176 335 2.6E-28 T 14-10-2018 A4R43_24275 723a9d55dd1522c3225a7e3501117039 341 SMART SM00354 13 85 5.1E-20 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_24275 723a9d55dd1522c3225a7e3501117039 341 SUPERFAMILY SSF53822 74 338 9.42E-32 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_24275 723a9d55dd1522c3225a7e3501117039 341 Gene3D G3DSA:1.10.260.40 5 72 3.9E-22 T 14-10-2018 A4R43_41720 ecf365d565b88c41d72c4be842dd2062 1080 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 21 758 3.5E-165 T 14-10-2018 IPR005887 Alpha-1,2-mannosidase, putative A4R43_41720 ecf365d565b88c41d72c4be842dd2062 1080 Gene3D G3DSA:3.30.2080.10 297 759 1.2E-246 T 14-10-2018 A4R43_41720 ecf365d565b88c41d72c4be842dd2062 1080 Pfam PF07971 Glycosyl hydrolase family 92 237 755 4.1E-147 T 14-10-2018 IPR012939 Glycosyl hydrolase family 92 A4R43_41720 ecf365d565b88c41d72c4be842dd2062 1080 SUPERFAMILY SSF48208 269 740 7.14E-25 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_41720 ecf365d565b88c41d72c4be842dd2062 1080 Gene3D G3DSA:1.20.1610.10 447 627 1.2E-246 T 14-10-2018 A4R43_41720 ecf365d565b88c41d72c4be842dd2062 1080 Gene3D G3DSA:1.20.1050.60 350 446 1.2E-246 T 14-10-2018 A4R43_41720 ecf365d565b88c41d72c4be842dd2062 1080 Gene3D G3DSA:2.70.98.10 29 349 1.2E-246 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_03360 6d2395c85d674dad681f0df47810c3a3 311 Pfam PF00005 ABC transporter 21 162 3.3E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_03360 6d2395c85d674dad681f0df47810c3a3 311 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 303 5.3E-96 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_03360 6d2395c85d674dad681f0df47810c3a3 311 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_03360 6d2395c85d674dad681f0df47810c3a3 311 Gene3D G3DSA:3.40.50.300 1 234 2.8E-63 T 14-10-2018 A4R43_03360 6d2395c85d674dad681f0df47810c3a3 311 SMART SM00382 30 211 2.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03360 6d2395c85d674dad681f0df47810c3a3 311 Pfam PF13732 Domain of unknown function (DUF4162) 216 301 7.1E-7 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 A4R43_03360 6d2395c85d674dad681f0df47810c3a3 311 SUPERFAMILY SSF52540 5 227 4.92E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33225 7dfd7185634eb2afd02fb92bef20e356 332 SUPERFAMILY SSF48576 19 331 3.04E-80 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_33225 7dfd7185634eb2afd02fb92bef20e356 332 Pfam PF00348 Polyprenyl synthetase 42 280 2.5E-57 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A4R43_33225 7dfd7185634eb2afd02fb92bef20e356 332 Gene3D G3DSA:1.10.600.10 4 332 3.3E-103 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_33225 7dfd7185634eb2afd02fb92bef20e356 332 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 213 225 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4R43_38975 484b137ac27431c3f1ebd4e2cca939d0 187 Gene3D G3DSA:1.20.120.450 1 133 5.5E-14 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_38975 484b137ac27431c3f1ebd4e2cca939d0 187 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 187 7.7E-25 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_38975 484b137ac27431c3f1ebd4e2cca939d0 187 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 10 187 4.5E-42 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_38975 484b137ac27431c3f1ebd4e2cca939d0 187 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 130 1.6E-15 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_38975 484b137ac27431c3f1ebd4e2cca939d0 187 SUPERFAMILY SSF109854 2 136 1.53E-20 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 Gene3D G3DSA:1.20.140.10 238 390 7.6E-36 T 14-10-2018 A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 Gene3D G3DSA:2.40.110.10 133 236 5.6E-35 T 14-10-2018 A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 224 2.9E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 130 3.5E-29 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 SUPERFAMILY SSF56645 7 235 5.1E-73 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 136 148 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 383 3.5E-28 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 Gene3D G3DSA:1.10.540.10 2 131 2.9E-38 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_17350 f6d72e401eeee220a7180590a5b9e5fc 390 SUPERFAMILY SSF47203 236 385 2.9E-38 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_33535 0a3046b879b2df8dde142259beb06836 295 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 21 270 1.7E-67 T 14-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted A4R43_33535 0a3046b879b2df8dde142259beb06836 295 SUPERFAMILY SSF51679 1 288 2.09E-60 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_33535 0a3046b879b2df8dde142259beb06836 295 Pfam PF00296 Luciferase-like monooxygenase 12 243 7.8E-50 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_33535 0a3046b879b2df8dde142259beb06836 295 Gene3D G3DSA:3.20.20.30 1 292 1.6E-66 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_00390 01e9c8a777b7d905cb7ad3fd7f5bea06 382 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 81 90 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4R43_00390 01e9c8a777b7d905cb7ad3fd7f5bea06 382 SUPERFAMILY SSF53187 3 376 5.71E-48 T 14-10-2018 A4R43_00390 01e9c8a777b7d905cb7ad3fd7f5bea06 382 Gene3D G3DSA:3.30.70.360 188 302 1.4E-65 T 14-10-2018 A4R43_00390 01e9c8a777b7d905cb7ad3fd7f5bea06 382 Pfam PF01546 Peptidase family M20/M25/M40 83 376 1.5E-29 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_00390 01e9c8a777b7d905cb7ad3fd7f5bea06 382 SUPERFAMILY SSF55031 187 302 1.18E-17 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_00390 01e9c8a777b7d905cb7ad3fd7f5bea06 382 Gene3D G3DSA:3.40.630.10 18 368 1.4E-65 T 14-10-2018 A4R43_00390 01e9c8a777b7d905cb7ad3fd7f5bea06 382 Pfam PF07687 Peptidase dimerisation domain 185 287 5.1E-12 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_18770 a7f9e67c9acf4df0c06777f862af4191 197 Pfam PF02620 Uncharacterized ACR, COG1399 73 181 1.0E-28 T 14-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 1.3E-140 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 436 38.876 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 SUPERFAMILY SSF53720 24 436 1.77E-70 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 Pfam PF00815 Histidinol dehydrogenase 23 436 5.0E-155 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 5.3E-88 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 5.3E-88 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 5.3E-88 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 5.3E-88 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 5.3E-88 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 5.3E-88 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 5.3E-88 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 5.3E-88 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 PIRSF PIRSF000099 1 438 1.7E-152 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 Gene3D G3DSA:3.40.50.1980 238 380 4.5E-50 T 14-10-2018 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 Gene3D G3DSA:3.40.50.1980 28 237 1.2E-60 T 14-10-2018 A4R43_17460 02a231bf13ab4c1938aff3a580f39180 438 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 14-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A4R43_14875 eb6652ef49f62b2e3d864929eb8960d7 237 PIRSF PIRSF039137 1 237 1.3E-108 T 14-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 A4R43_14875 eb6652ef49f62b2e3d864929eb8960d7 237 Pfam PF00005 ABC transporter 20 164 4.3E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14875 eb6652ef49f62b2e3d864929eb8960d7 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_14875 eb6652ef49f62b2e3d864929eb8960d7 237 Gene3D G3DSA:3.40.50.300 1 237 2.3E-64 T 14-10-2018 A4R43_14875 eb6652ef49f62b2e3d864929eb8960d7 237 SMART SM00382 28 215 2.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14875 eb6652ef49f62b2e3d864929eb8960d7 237 SUPERFAMILY SSF52540 3 233 1.87E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27920 df4a98c291991d7218ddf9a3c6f00ef5 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 105 184 7.8E-27 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_27920 df4a98c291991d7218ddf9a3c6f00ef5 328 SUPERFAMILY SSF53901 7 323 3.81E-65 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_27920 df4a98c291991d7218ddf9a3c6f00ef5 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 322 9.8E-104 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_27920 df4a98c291991d7218ddf9a3c6f00ef5 328 Gene3D G3DSA:3.40.47.10 1 327 2.3E-117 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_27920 df4a98c291991d7218ddf9a3c6f00ef5 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 233 322 1.7E-34 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_27920 df4a98c291991d7218ddf9a3c6f00ef5 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 322 61.662 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_27555 8fcce1f87faca3bef4616a64473b359e 216 Pfam PF01205 Uncharacterized protein family UPF0029 29 134 1.0E-26 T 14-10-2018 IPR001498 Impact, N-terminal A4R43_27555 8fcce1f87faca3bef4616a64473b359e 216 SUPERFAMILY SSF54211 16 141 3.57E-37 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_27555 8fcce1f87faca3bef4616a64473b359e 216 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 15 209 1.5E-52 T 14-10-2018 IPR015796 Impact family, bacterial/archaeal A4R43_27555 8fcce1f87faca3bef4616a64473b359e 216 Pfam PF09186 Domain of unknown function (DUF1949) 150 204 3.5E-12 T 14-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A4R43_27555 8fcce1f87faca3bef4616a64473b359e 216 Gene3D G3DSA:3.30.230.30 11 142 4.6E-47 T 14-10-2018 IPR036956 Impact, N-terminal domain superfamily A4R43_27555 8fcce1f87faca3bef4616a64473b359e 216 SUPERFAMILY SSF54980 147 212 6.98E-10 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 Gene3D G3DSA:3.30.160.70 1 70 7.8E-23 T 14-10-2018 A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 75 154 1.6E-36 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 Gene3D G3DSA:1.10.10.10 74 157 8.9E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 125 131 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 5 71 3.9E-10 T 14-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 155 45.248 T 14-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 76 156 1.7E-32 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 SUPERFAMILY SSF46767 74 156 2.88E-32 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A4R43_05305 6b58ee47fa4f8d623852d39207094015 163 SUPERFAMILY SSF53155 4 79 8.44E-19 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 Gene3D G3DSA:1.10.1660.10 6 117 4.1E-12 T 14-10-2018 A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 Pfam PF00376 MerR family regulatory protein 6 41 2.6E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 Pfam PF13411 MerR HTH family regulatory protein 121 188 4.0E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 Gene3D G3DSA:1.10.1660.10 118 230 7.8E-18 T 14-10-2018 A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 SUPERFAMILY SSF46955 7 106 4.4E-12 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 ProSitePatterns PS00552 MerR-type HTH domain signature. 123 145 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 SMART SM00422 121 189 4.6E-4 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 SMART SM00422 4 71 0.0031 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23640 19d404e4f26dfaecdfdc7dc0e2401da5 236 SUPERFAMILY SSF46955 121 227 7.78E-16 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_26475 b566b44ee3b0374ff482a82df7bf7e7f 331 Gene3D G3DSA:1.10.10.60 219 329 9.7E-27 T 14-10-2018 A4R43_26475 b566b44ee3b0374ff482a82df7bf7e7f 331 Pfam PF12833 Helix-turn-helix domain 244 326 4.2E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_26475 b566b44ee3b0374ff482a82df7bf7e7f 331 SUPERFAMILY SSF46689 275 326 2.36E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_26475 b566b44ee3b0374ff482a82df7bf7e7f 331 SMART SM00342 237 324 1.1E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_26475 b566b44ee3b0374ff482a82df7bf7e7f 331 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 308 324 7.0E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_26475 b566b44ee3b0374ff482a82df7bf7e7f 331 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 293 308 7.0E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_26475 b566b44ee3b0374ff482a82df7bf7e7f 331 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 275 320 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_26475 b566b44ee3b0374ff482a82df7bf7e7f 331 Pfam PF14525 AraC-binding-like domain 55 183 1.4E-6 T 14-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like A4R43_13480 9d19b1ff2d90ee802bbf69e4e7fbe641 229 SUPERFAMILY SSF53474 3 228 1.45E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13480 9d19b1ff2d90ee802bbf69e4e7fbe641 229 Pfam PF12697 Alpha/beta hydrolase family 14 200 2.8E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13480 9d19b1ff2d90ee802bbf69e4e7fbe641 229 Gene3D G3DSA:3.40.50.1820 1 229 1.6E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 Pfam PF04539 Sigma-70 region 3 122 186 3.1E-15 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 Gene3D G3DSA:1.20.140.160 112 259 3.4E-36 T 14-10-2018 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 SUPERFAMILY SSF88946 13 108 3.92E-28 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 Pfam PF04542 Sigma-70 region 2 39 108 1.7E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 PRINTS PR00046 Major sigma-70 factor signature 63 76 2.4E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 PRINTS PR00046 Major sigma-70 factor signature 241 252 2.4E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 PRINTS PR00046 Major sigma-70 factor signature 209 221 2.4E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 PRINTS PR00046 Major sigma-70 factor signature 226 241 2.4E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 SUPERFAMILY SSF88659 112 187 5.23E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 Pfam PF04545 Sigma-70, region 4 206 254 7.3E-16 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 SUPERFAMILY SSF88659 175 257 5.05E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 255 1.4E-33 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 33 256 1.4E-90 T 14-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_27885 4e555234dee60d66c85cbcb34977bfae 262 Gene3D G3DSA:1.10.601.10 19 111 7.9E-17 T 14-10-2018 A4R43_24890 4a14752c2b31cdd369e3672dfe19ef6b 319 Gene3D G3DSA:1.10.443.10 112 311 4.7E-33 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_24890 4a14752c2b31cdd369e3672dfe19ef6b 319 Gene3D G3DSA:1.10.150.130 1 94 4.0E-12 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_24890 4a14752c2b31cdd369e3672dfe19ef6b 319 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 85 1.9E-6 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4R43_24890 4a14752c2b31cdd369e3672dfe19ef6b 319 SUPERFAMILY SSF47823 9 81 1.82E-6 T 14-10-2018 A4R43_24890 4a14752c2b31cdd369e3672dfe19ef6b 319 Pfam PF00589 Phage integrase family 125 288 2.9E-27 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_24890 4a14752c2b31cdd369e3672dfe19ef6b 319 SUPERFAMILY SSF56349 114 296 2.8E-36 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_33930 4b4c165cd3b379efbd6ac4efc459ddca 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 14-10-2018 IPR018038 Ribosomal protein L30, conserved site A4R43_33930 4b4c165cd3b379efbd6ac4efc459ddca 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 8.2E-24 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33930 4b4c165cd3b379efbd6ac4efc459ddca 61 PIRSF PIRSF002211 1 60 4.8E-28 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33930 4b4c165cd3b379efbd6ac4efc459ddca 61 Gene3D G3DSA:3.30.1390.20 1 60 4.2E-25 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A4R43_33930 4b4c165cd3b379efbd6ac4efc459ddca 61 SUPERFAMILY SSF55129 1 59 2.75E-21 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A4R43_33930 4b4c165cd3b379efbd6ac4efc459ddca 61 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 6.9E-18 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A4R43_33930 4b4c165cd3b379efbd6ac4efc459ddca 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.604 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_23355 212b4a11f46abe6c8d7714d332c3c8fb 580 SUPERFAMILY SSF53850 37 575 3.62E-60 T 14-10-2018 A4R43_23355 212b4a11f46abe6c8d7714d332c3c8fb 580 Gene3D G3DSA:3.40.190.10 42 563 4.5E-168 T 14-10-2018 A4R43_23355 212b4a11f46abe6c8d7714d332c3c8fb 580 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 106 430 7.9E-37 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_23355 212b4a11f46abe6c8d7714d332c3c8fb 580 Gene3D G3DSA:3.90.76.10 74 187 4.5E-168 T 14-10-2018 A4R43_23355 212b4a11f46abe6c8d7714d332c3c8fb 580 Gene3D G3DSA:3.10.105.10 293 547 4.5E-168 T 14-10-2018 A4R43_34840 f9710b4951cc23b4cace80ce02c85545 479 Gene3D G3DSA:3.40.605.10 28 478 2.3E-174 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_34840 f9710b4951cc23b4cace80ce02c85545 479 Gene3D G3DSA:3.40.309.10 263 452 2.3E-174 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_34840 f9710b4951cc23b4cace80ce02c85545 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_34840 f9710b4951cc23b4cace80ce02c85545 479 SUPERFAMILY SSF53720 19 478 1.44E-161 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_34840 f9710b4951cc23b4cace80ce02c85545 479 Pfam PF00171 Aldehyde dehydrogenase family 37 478 5.0E-165 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_28465 6bfc5a7a672e0ae8dbb68957d708756f 105 PIRSF PIRSF029826 1 105 3.4E-40 T 14-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A4R43_28465 6bfc5a7a672e0ae8dbb68957d708756f 105 Gene3D G3DSA:1.10.287.1080 1 105 1.8E-34 T 14-10-2018 A4R43_28465 6bfc5a7a672e0ae8dbb68957d708756f 105 SUPERFAMILY SSF101386 2 104 2.13E-33 T 14-10-2018 A4R43_28465 6bfc5a7a672e0ae8dbb68957d708756f 105 Pfam PF12643 MazG-like family 32 100 9.1E-9 T 14-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A4R43_02160 0c8d9cb50989752bbd6efb4cc729f673 298 Pfam PF13565 Homeodomain-like domain 8 75 3.2E-10 T 14-10-2018 A4R43_02160 0c8d9cb50989752bbd6efb4cc729f673 298 Gene3D G3DSA:3.30.420.10 128 293 2.5E-28 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_02160 0c8d9cb50989752bbd6efb4cc729f673 298 SUPERFAMILY SSF53098 101 292 8.73E-37 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_02160 0c8d9cb50989752bbd6efb4cc729f673 298 Pfam PF00665 Integrase core domain 99 249 5.0E-43 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_09045 4ee13dcd5676f5354369c35df441f0e8 347 Gene3D G3DSA:3.20.20.30 11 342 3.3E-88 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_09045 4ee13dcd5676f5354369c35df441f0e8 347 Pfam PF00296 Luciferase-like monooxygenase 17 317 2.8E-86 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_09045 4ee13dcd5676f5354369c35df441f0e8 347 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 321 4.4E-123 T 14-10-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c A4R43_09045 4ee13dcd5676f5354369c35df441f0e8 347 SUPERFAMILY SSF51679 6 341 4.32E-74 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 PIRSF PIRSF016578 218 349 2.2E-7 T 14-10-2018 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 PIRSF PIRSF016578 2 174 1.1E-4 T 14-10-2018 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 106 196 3.4E-17 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 SUPERFAMILY SSF56645 6 208 9.16E-50 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 214 358 1.9E-33 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 101 5.4E-17 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 SUPERFAMILY SSF47203 215 360 2.42E-34 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 Gene3D G3DSA:2.40.110.10 106 206 6.2E-22 T 14-10-2018 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 Gene3D G3DSA:1.20.140.10 211 361 2.0E-35 T 14-10-2018 A4R43_12705 98e5a1ccbb8e603f3c5ac0dfc9b9cb76 370 Gene3D G3DSA:1.10.540.10 3 102 2.8E-22 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_40515 8464ce49801bfcf77fa6851d0103a91b 334 Gene3D G3DSA:1.10.260.40 1 59 7.6E-21 T 14-10-2018 A4R43_40515 8464ce49801bfcf77fa6851d0103a91b 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 2.2E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_40515 8464ce49801bfcf77fa6851d0103a91b 334 Gene3D G3DSA:3.40.50.2300 79 311 1.5E-42 T 14-10-2018 A4R43_40515 8464ce49801bfcf77fa6851d0103a91b 334 SMART SM00354 1 71 1.1E-23 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_40515 8464ce49801bfcf77fa6851d0103a91b 334 SUPERFAMILY SSF47413 1 59 1.3E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_40515 8464ce49801bfcf77fa6851d0103a91b 334 Gene3D G3DSA:3.40.50.2300 160 291 1.5E-42 T 14-10-2018 A4R43_40515 8464ce49801bfcf77fa6851d0103a91b 334 SUPERFAMILY SSF53822 58 323 1.33E-38 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_40515 8464ce49801bfcf77fa6851d0103a91b 334 Pfam PF13377 Periplasmic binding protein-like domain 168 330 7.0E-29 T 14-10-2018 A4R43_37975 01e52873869c4622f6110b93618443be 261 PIRSF PIRSF020623 1 261 6.0E-54 T 14-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 A4R43_37975 01e52873869c4622f6110b93618443be 261 SUPERFAMILY SSF46785 24 111 3.16E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_37975 01e52873869c4622f6110b93618443be 261 Gene3D G3DSA:1.10.10.10 1 78 9.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37975 01e52873869c4622f6110b93618443be 261 Pfam PF08223 PaaX-like protein C-terminal domain 165 256 2.3E-19 T 14-10-2018 IPR013225 PaaX-like, C-terminal A4R43_37975 01e52873869c4622f6110b93618443be 261 Pfam PF07848 PaaX-like protein 1 64 2.5E-14 T 14-10-2018 IPR012906 PaaX-like, N-terminal A4R43_20215 695c5244b76f6cc86e659803f71a42b6 533 SUPERFAMILY SSF51645 6 530 5.75E-184 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_20215 695c5244b76f6cc86e659803f71a42b6 533 ProSitePatterns PS00510 Malate synthase signature. 266 281 - T 14-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_20215 695c5244b76f6cc86e659803f71a42b6 533 Gene3D G3DSA:3.20.20.360 3 411 5.7E-191 T 14-10-2018 A4R43_20215 695c5244b76f6cc86e659803f71a42b6 533 Pfam PF01274 Malate synthase 11 528 3.2E-196 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_20215 695c5244b76f6cc86e659803f71a42b6 533 Gene3D G3DSA:1.20.1220.12 414 530 4.3E-40 T 14-10-2018 A4R43_20215 695c5244b76f6cc86e659803f71a42b6 533 PIRSF PIRSF001363 1 532 5.2E-238 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_20215 695c5244b76f6cc86e659803f71a42b6 533 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 22 529 1.1E-233 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_11415 95469ef74ad6d4a8ea7579912628bd4f 185 SUPERFAMILY SSF48498 108 164 8.9E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11415 95469ef74ad6d4a8ea7579912628bd4f 185 SUPERFAMILY SSF46689 8 70 2.29E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11415 95469ef74ad6d4a8ea7579912628bd4f 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 1.3E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11415 95469ef74ad6d4a8ea7579912628bd4f 185 Gene3D G3DSA:1.10.357.10 1 185 3.2E-56 T 14-10-2018 A4R43_12775 31ec857dbb006debc8ce8ca38ea6d2f5 103 SUPERFAMILY SSF46565 6 74 5.1E-18 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_12775 31ec857dbb006debc8ce8ca38ea6d2f5 103 Gene3D G3DSA:1.10.287.110 3 82 4.4E-17 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_12775 31ec857dbb006debc8ce8ca38ea6d2f5 103 SMART SM00271 7 62 1.0E-9 T 14-10-2018 IPR001623 DnaJ domain A4R43_12775 31ec857dbb006debc8ce8ca38ea6d2f5 103 Pfam PF00226 DnaJ domain 8 67 2.0E-11 T 14-10-2018 IPR001623 DnaJ domain A4R43_12775 31ec857dbb006debc8ce8ca38ea6d2f5 103 PRINTS PR00625 DnaJ domain signature 28 43 3.9E-5 T 14-10-2018 IPR001623 DnaJ domain A4R43_12775 31ec857dbb006debc8ce8ca38ea6d2f5 103 PRINTS PR00625 DnaJ domain signature 10 28 3.9E-5 T 14-10-2018 IPR001623 DnaJ domain A4R43_13230 252726aee2eb514de6852c4bfcd4958c 399 Gene3D G3DSA:3.90.1510.10 46 282 5.1E-119 T 14-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 A4R43_13230 252726aee2eb514de6852c4bfcd4958c 399 SUPERFAMILY SSF110738 6 381 3.27E-112 T 14-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 A4R43_13230 252726aee2eb514de6852c4bfcd4958c 399 Pfam PF02595 Glycerate kinase family 8 379 3.5E-126 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_13230 252726aee2eb514de6852c4bfcd4958c 399 PIRSF PIRSF006078 5 383 1.2E-105 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_13230 252726aee2eb514de6852c4bfcd4958c 399 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 6 380 3.2E-128 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_13230 252726aee2eb514de6852c4bfcd4958c 399 Gene3D G3DSA:3.40.50.10350 6 368 5.1E-119 T 14-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold A4R43_03180 1a6c714cdce629ef395fee627641108a 267 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 219 261 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_03180 1a6c714cdce629ef395fee627641108a 267 Pfam PF12833 Helix-turn-helix domain 188 266 1.9E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03180 1a6c714cdce629ef395fee627641108a 267 SMART SM00342 182 265 3.0E-31 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03180 1a6c714cdce629ef395fee627641108a 267 SUPERFAMILY SSF46689 166 216 3.45E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03180 1a6c714cdce629ef395fee627641108a 267 Gene3D G3DSA:1.10.10.60 225 267 1.2E-14 T 14-10-2018 A4R43_03180 1a6c714cdce629ef395fee627641108a 267 SUPERFAMILY SSF46689 218 266 1.84E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03180 1a6c714cdce629ef395fee627641108a 267 Gene3D G3DSA:1.10.10.60 165 224 1.2E-13 T 14-10-2018 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 Gene3D G3DSA:2.40.10.10 257 356 5.6E-66 T 14-10-2018 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 209 223 1.1E-38 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 334 348 1.1E-38 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 310 333 1.1E-38 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 291 308 1.1E-38 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 270 290 1.1E-38 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 Pfam PF02983 Alpha-lytic protease prodomain 113 168 1.6E-8 T 14-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 319 330 - T 14-10-2018 IPR033116 Serine proteases, trypsin family, serine active site A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 Gene3D G3DSA:2.40.10.10 188 367 5.6E-66 T 14-10-2018 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 Pfam PF00089 Trypsin 276 360 3.1E-10 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 PIRSF PIRSF001134 1 371 1.1E-119 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 SUPERFAMILY SSF50494 192 362 2.85E-33 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_40565 80ccb3c6ec5cc184134668ffd26b13b5 371 Gene3D G3DSA:3.30.300.50 28 105 3.3E-12 T 14-10-2018 IPR035070 Streptogrisin prodomain A4R43_31485 e064bfa605e4c4b5fa5e43470b56afce 345 Gene3D G3DSA:3.40.50.2300 167 296 5.9E-76 T 14-10-2018 A4R43_31485 e064bfa605e4c4b5fa5e43470b56afce 345 Gene3D G3DSA:3.40.50.2300 63 313 5.9E-76 T 14-10-2018 A4R43_31485 e064bfa605e4c4b5fa5e43470b56afce 345 SMART SM00354 8 78 1.3E-19 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_31485 e064bfa605e4c4b5fa5e43470b56afce 345 SUPERFAMILY SSF53822 67 338 1.96E-72 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_31485 e064bfa605e4c4b5fa5e43470b56afce 345 SUPERFAMILY SSF47413 8 66 7.93E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_31485 e064bfa605e4c4b5fa5e43470b56afce 345 Gene3D G3DSA:1.10.260.40 10 62 1.7E-19 T 14-10-2018 A4R43_31485 e064bfa605e4c4b5fa5e43470b56afce 345 Pfam PF13377 Periplasmic binding protein-like domain 175 336 1.2E-39 T 14-10-2018 A4R43_31485 e064bfa605e4c4b5fa5e43470b56afce 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 53 8.4E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_05600 1b2378021ecc9472b59abe465c62d693 460 Pfam PF01039 Carboxyl transferase domain 28 447 6.1E-125 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_05600 1b2378021ecc9472b59abe465c62d693 460 SUPERFAMILY SSF52096 5 201 2.89E-46 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_05600 1b2378021ecc9472b59abe465c62d693 460 Gene3D G3DSA:3.90.226.10 210 460 2.3E-79 T 14-10-2018 A4R43_05600 1b2378021ecc9472b59abe465c62d693 460 SUPERFAMILY SSF52096 213 450 1.38E-75 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_05600 1b2378021ecc9472b59abe465c62d693 460 Gene3D G3DSA:3.90.226.10 4 203 5.8E-54 T 14-10-2018 A4R43_01815 6efaa9ad072759626b106dd4144b5b3e 430 Pfam PF08484 C-methyltransferase C-terminal domain 249 407 1.2E-47 T 14-10-2018 IPR013691 C-methyltransferase A4R43_01815 6efaa9ad072759626b106dd4144b5b3e 430 Gene3D G3DSA:3.40.50.720 314 420 4.9E-32 T 14-10-2018 A4R43_01815 6efaa9ad072759626b106dd4144b5b3e 430 SUPERFAMILY SSF53335 68 248 9.2E-13 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_01815 6efaa9ad072759626b106dd4144b5b3e 430 Gene3D G3DSA:3.40.50.150 62 260 1.8E-26 T 14-10-2018 A4R43_01815 6efaa9ad072759626b106dd4144b5b3e 430 Pfam PF13489 Methyltransferase domain 101 242 1.6E-8 T 14-10-2018 A4R43_01815 6efaa9ad072759626b106dd4144b5b3e 430 Pfam PF08421 Putative zinc binding domain 9 69 1.7E-14 T 14-10-2018 IPR013630 Methyltransferase putative zinc binding domain A4R43_01815 6efaa9ad072759626b106dd4144b5b3e 430 Gene3D G3DSA:2.20.25.520 2 59 1.1E-6 T 14-10-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily A4R43_25630 0b44efa5e8535f86b5a275c2c7018157 100 PIRSF PIRSF001223 1 100 1.9E-48 T 14-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25630 0b44efa5e8535f86b5a275c2c7018157 100 Pfam PF00547 Urease, gamma subunit 1 99 3.9E-46 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25630 0b44efa5e8535f86b5a275c2c7018157 100 SUPERFAMILY SSF54111 1 99 2.22E-43 T 14-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25630 0b44efa5e8535f86b5a275c2c7018157 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 6.6E-46 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25630 0b44efa5e8535f86b5a275c2c7018157 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 8.0E-35 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25630 0b44efa5e8535f86b5a275c2c7018157 100 Gene3D G3DSA:3.30.280.10 1 100 1.1E-46 T 14-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_25630 0b44efa5e8535f86b5a275c2c7018157 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.192 T 14-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 Gene3D G3DSA:3.50.50.60 3 298 1.5E-102 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 SUPERFAMILY SSF55424 312 387 1.51E-17 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 298 5.5E-57 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 SUPERFAMILY SSF51905 2 188 1.46E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 SUPERFAMILY SSF51905 142 307 2.78E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 Gene3D G3DSA:3.50.50.60 112 236 1.5E-102 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 Gene3D G3DSA:3.30.390.30 318 395 3.0E-15 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 1.5E-18 T 14-10-2018 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 230 244 1.5E-18 T 14-10-2018 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 1.5E-18 T 14-10-2018 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.5E-18 T 14-10-2018 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 Pfam PF14759 Reductase C-terminal 318 387 7.1E-14 T 14-10-2018 IPR028202 Reductase, C-terminal A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 3.7E-21 T 14-10-2018 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.7E-21 T 14-10-2018 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 3.7E-21 T 14-10-2018 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 3.7E-21 T 14-10-2018 A4R43_37415 5ab97f404fbe57a35be6db9330ebd843 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 3.7E-21 T 14-10-2018 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 SUPERFAMILY SSF53738 154 256 1.18E-29 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 SUPERFAMILY SSF55957 368 452 5.23E-18 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 155 254 5.3E-26 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 450 5.6E-15 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 205 218 9.9E-21 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 9.9E-21 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 9.9E-21 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 171 190 9.9E-21 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 368 2.0E-27 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 SUPERFAMILY SSF53738 260 364 5.89E-31 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 124 4.2E-30 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 Gene3D G3DSA:3.30.310.50 369 452 1.2E-19 T 14-10-2018 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 Gene3D G3DSA:3.40.120.10 173 250 1.0E-33 T 14-10-2018 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 Gene3D G3DSA:3.40.120.10 251 367 3.4E-36 T 14-10-2018 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 SUPERFAMILY SSF53738 7 123 7.06E-31 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_23285 bdb071bed428c424a1601ea7183fb8ea 452 Gene3D G3DSA:3.40.120.10 5 149 7.6E-43 T 14-10-2018 A4R43_17335 ecde8fdb45d900466a35a6e484f8b0b7 1039 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 541 647 9.3E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_17335 ecde8fdb45d900466a35a6e484f8b0b7 1039 Gene3D G3DSA:3.30.565.10 474 637 4.7E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_17335 ecde8fdb45d900466a35a6e484f8b0b7 1039 SMART SM00387 537 650 2.4E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_17335 ecde8fdb45d900466a35a6e484f8b0b7 1039 Pfam PF08376 Nitrate and nitrite sensing 78 315 1.1E-32 T 14-10-2018 IPR013587 Nitrate/nitrite sensing protein A4R43_17335 ecde8fdb45d900466a35a6e484f8b0b7 1039 SUPERFAMILY SSF55874 525 647 4.32E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_01575 65e1a307045436ae28e213be6c5f2ef6 208 SUPERFAMILY SSF46785 5 109 8.73E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01575 65e1a307045436ae28e213be6c5f2ef6 208 Pfam PF01638 HxlR-like helix-turn-helix 17 99 2.3E-17 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_01575 65e1a307045436ae28e213be6c5f2ef6 208 Gene3D G3DSA:1.10.10.10 2 113 6.3E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19000 0465de391e96eacc43823110de9768db 385 SMART SM00922 153 250 2.3E-22 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_19000 0465de391e96eacc43823110de9768db 385 Gene3D G3DSA:3.20.20.120 127 364 2.9E-100 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_19000 0465de391e96eacc43823110de9768db 385 Gene3D G3DSA:3.30.390.10 6 369 2.9E-100 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_19000 0465de391e96eacc43823110de9768db 385 SUPERFAMILY SSF54826 6 135 3.7E-24 T 14-10-2018 A4R43_19000 0465de391e96eacc43823110de9768db 385 Pfam PF13378 Enolase C-terminal domain-like 156 370 1.6E-54 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_19000 0465de391e96eacc43823110de9768db 385 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 130 2.9E-17 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_19000 0465de391e96eacc43823110de9768db 385 SUPERFAMILY SSF51604 123 376 7.6E-64 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 SUPERFAMILY SSF69742 2 158 3.4E-42 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 PIRSF PIRSF000445 1 431 7.7E-129 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 Gene3D G3DSA:3.30.460.30 1 158 9.2E-54 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 3.1E-43 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 SUPERFAMILY SSF69075 318 419 2.22E-16 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 169 300 3.8E-29 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 Gene3D G3DSA:3.40.50.720 161 308 2.4E-35 T 14-10-2018 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 416 26.09 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 419 9.8E-120 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 319 418 7.4E-21 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 14-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4R43_32920 02608f7e69b1df5c5f92a070a947f05a 440 SUPERFAMILY SSF51735 164 298 3.41E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 156 4.4E-36 T 14-10-2018 IPR023635 Peptide deformylase A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 PIRSF PIRSF004749 1 162 2.2E-40 T 14-10-2018 IPR023635 Peptide deformylase A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 SUPERFAMILY SSF56420 3 161 7.33E-50 T 14-10-2018 IPR036821 Peptide deformylase superfamily A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 Pfam PF01327 Polypeptide deformylase 5 150 4.5E-40 T 14-10-2018 IPR023635 Peptide deformylase A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 Hamap MF_00163 Peptide deformylase [def]. 2 160 25.911 T 14-10-2018 IPR023635 Peptide deformylase A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 Gene3D G3DSA:3.90.45.10 1 166 2.3E-47 T 14-10-2018 IPR036821 Peptide deformylase superfamily A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 PRINTS PR01576 Peptide deformylase signature 33 62 2.2E-25 T 14-10-2018 IPR023635 Peptide deformylase A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 PRINTS PR01576 Peptide deformylase signature 99 117 2.2E-25 T 14-10-2018 IPR023635 Peptide deformylase A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 PRINTS PR01576 Peptide deformylase signature 87 98 2.2E-25 T 14-10-2018 IPR023635 Peptide deformylase A4R43_16985 a0e1518a05070024b081ca0aeeb5aef1 167 PRINTS PR01576 Peptide deformylase signature 118 147 2.2E-25 T 14-10-2018 IPR023635 Peptide deformylase A4R43_04480 7e8000301d565480bde496b81a44bce5 251 SUPERFAMILY SSF52266 1 185 2.75E-28 T 14-10-2018 A4R43_04480 7e8000301d565480bde496b81a44bce5 251 Gene3D G3DSA:3.40.50.1110 1 188 4.4E-23 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_04480 7e8000301d565480bde496b81a44bce5 251 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 1 175 2.2E-21 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 Pfam PF00067 Cytochrome P450 40 371 6.6E-32 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 SUPERFAMILY SSF48264 16 399 1.31E-91 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 Gene3D G3DSA:1.10.630.10 5 400 4.0E-125 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 349 360 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 126 142 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 193 215 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 291 318 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 319 334 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 143 158 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 340 349 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 81 92 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05970 afd007cb1f42a28f3d03ae1cb81430c3 400 PRINTS PR00359 B-class P450 signature 274 285 2.0E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11060 b946dba9a02af5c002d522e5e9ce257a 312 SUPERFAMILY SSF53850 26 309 4.04E-54 T 14-10-2018 A4R43_11060 b946dba9a02af5c002d522e5e9ce257a 312 Pfam PF16868 NMT1-like family 32 309 8.6E-49 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A4R43_11060 b946dba9a02af5c002d522e5e9ce257a 312 Gene3D G3DSA:3.40.190.10 32 309 2.9E-67 T 14-10-2018 A4R43_11060 b946dba9a02af5c002d522e5e9ce257a 312 Gene3D G3DSA:3.40.190.10 114 247 2.9E-67 T 14-10-2018 A4R43_11060 b946dba9a02af5c002d522e5e9ce257a 312 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 309 2.0E-58 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A4R43_36955 6b64dafdb0def4efba00f10783c7c9c9 209 SUPERFAMILY SSF46955 1 88 4.76E-17 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_36955 6b64dafdb0def4efba00f10783c7c9c9 209 Gene3D G3DSA:1.10.1660.10 2 207 7.0E-56 T 14-10-2018 A4R43_36955 6b64dafdb0def4efba00f10783c7c9c9 209 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.2E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36955 6b64dafdb0def4efba00f10783c7c9c9 209 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.2E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36955 6b64dafdb0def4efba00f10783c7c9c9 209 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.2E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36955 6b64dafdb0def4efba00f10783c7c9c9 209 Pfam PF13411 MerR HTH family regulatory protein 1 69 4.5E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36955 6b64dafdb0def4efba00f10783c7c9c9 209 SMART SM00422 1 71 5.6E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_06275 f999e486e323dbfbcaab7367a6f486fc 171 Gene3D G3DSA:3.30.530.20 10 170 2.7E-38 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_06275 f999e486e323dbfbcaab7367a6f486fc 171 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 13 127 2.7E-12 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_06275 f999e486e323dbfbcaab7367a6f486fc 171 SUPERFAMILY SSF55961 12 169 7.33E-18 T 14-10-2018 A4R43_30040 b1aba606bcbb5125624053eb6c2138a6 149 Pfam PF00378 Enoyl-CoA hydratase/isomerase 1 145 8.6E-27 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_30040 b1aba606bcbb5125624053eb6c2138a6 149 SUPERFAMILY SSF52096 1 147 4.98E-30 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_30040 b1aba606bcbb5125624053eb6c2138a6 149 Gene3D G3DSA:3.90.226.10 1 147 4.1E-25 T 14-10-2018 A4R43_27130 7f67f4f05101ae159a703b95067e974d 406 Gene3D G3DSA:1.20.1530.10 13 396 6.3E-131 T 14-10-2018 IPR023171 Na/H antiporter domain superfamily A4R43_27130 7f67f4f05101ae159a703b95067e974d 406 Pfam PF06965 Na+/H+ antiporter 1 17 388 1.3E-128 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4R43_27130 7f67f4f05101ae159a703b95067e974d 406 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 19 387 1.9E-100 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4R43_27130 7f67f4f05101ae159a703b95067e974d 406 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 15 394 20.505 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4R43_38890 66d7e813e0958fd0d06c05744d79b351 428 Pfam PF07690 Major Facilitator Superfamily 18 375 1.0E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_38890 66d7e813e0958fd0d06c05744d79b351 428 SUPERFAMILY SSF103473 10 418 1.01E-60 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_38890 66d7e813e0958fd0d06c05744d79b351 428 ProSitePatterns PS00216 Sugar transport proteins signature 1. 294 311 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_38890 66d7e813e0958fd0d06c05744d79b351 428 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_38890 66d7e813e0958fd0d06c05744d79b351 428 Gene3D G3DSA:1.20.1250.20 10 427 8.9E-64 T 14-10-2018 A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 Gene3D G3DSA:1.10.260.40 5 69 1.4E-19 T 14-10-2018 A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 Gene3D G3DSA:3.40.50.2300 70 316 1.0E-70 T 14-10-2018 A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 SUPERFAMILY SSF47413 6 61 6.14E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 SUPERFAMILY SSF53822 65 341 1.07E-64 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 SMART SM00354 6 76 3.5E-25 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 Gene3D G3DSA:3.40.50.2300 172 301 1.0E-70 T 14-10-2018 A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 14-10-2018 A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 4.7E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_18995 e09903b1a6f13d71e53079335d32cd39 343 Pfam PF13377 Periplasmic binding protein-like domain 181 339 3.2E-32 T 14-10-2018 A4R43_07065 56659710cb58804ccea234f72e4b33fd 325 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 321 1.5E-116 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 A4R43_07065 56659710cb58804ccea234f72e4b33fd 325 Gene3D G3DSA:3.20.20.30 1 323 3.5E-101 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_07065 56659710cb58804ccea234f72e4b33fd 325 Pfam PF00296 Luciferase-like monooxygenase 16 297 4.5E-37 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_07065 56659710cb58804ccea234f72e4b33fd 325 SUPERFAMILY SSF51679 2 320 1.1E-77 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_32505 7b11bb253dad424ab7cad0a84a79d4f3 394 Gene3D G3DSA:2.60.40.3710 146 391 2.3E-93 T 14-10-2018 A4R43_32505 7b11bb253dad424ab7cad0a84a79d4f3 394 Gene3D G3DSA:2.60.40.3780 43 137 4.1E-30 T 14-10-2018 A4R43_32505 7b11bb253dad424ab7cad0a84a79d4f3 394 Gene3D G3DSA:2.40.440.10 243 379 2.3E-93 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_32505 7b11bb253dad424ab7cad0a84a79d4f3 394 SUPERFAMILY SSF141523 243 362 1.57E-24 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_32505 7b11bb253dad424ab7cad0a84a79d4f3 394 Pfam PF03734 L,D-transpeptidase catalytic domain 246 362 1.9E-15 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4R43_40650 1aadf1d8ba7c9e92af48165e08b4e9f6 140 Pfam PF01042 Endoribonuclease L-PSP 26 139 1.4E-20 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4R43_40650 1aadf1d8ba7c9e92af48165e08b4e9f6 140 SUPERFAMILY SSF55298 25 140 1.73E-26 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_40650 1aadf1d8ba7c9e92af48165e08b4e9f6 140 Gene3D G3DSA:3.30.1330.40 20 140 2.9E-27 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_00885 e83c8dfbd8544866e6c64a8d1ef27e29 284 Pfam PF01380 SIS domain 122 247 1.7E-9 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_00885 e83c8dfbd8544866e6c64a8d1ef27e29 284 Gene3D G3DSA:3.40.50.10490 88 271 1.5E-23 T 14-10-2018 A4R43_00885 e83c8dfbd8544866e6c64a8d1ef27e29 284 SUPERFAMILY SSF46689 4 69 2.33E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00885 e83c8dfbd8544866e6c64a8d1ef27e29 284 SUPERFAMILY SSF53697 94 251 5.78E-16 T 14-10-2018 A4R43_00885 e83c8dfbd8544866e6c64a8d1ef27e29 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 64 1.3E-12 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A4R43_00885 e83c8dfbd8544866e6c64a8d1ef27e29 284 Gene3D G3DSA:1.10.10.10 1 73 2.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35155 0c7a95f8fc46b66cea4e37c12c057eed 351 PIRSF PIRSF001112 197 351 6.3E-18 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_35155 0c7a95f8fc46b66cea4e37c12c057eed 351 PIRSF PIRSF001112 1 209 1.2E-64 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_35155 0c7a95f8fc46b66cea4e37c12c057eed 351 SUPERFAMILY SSF53474 2 349 9.0E-81 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35155 0c7a95f8fc46b66cea4e37c12c057eed 351 Gene3D G3DSA:3.40.50.1820 1 351 2.0E-107 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35155 0c7a95f8fc46b66cea4e37c12c057eed 351 Pfam PF06441 Epoxide hydrolase N terminus 5 110 1.3E-36 T 14-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 A4R43_08675 7009b783a0fc91e28dcd74f0de77be09 416 Gene3D G3DSA:1.10.150.130 114 182 5.9E-9 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_08675 7009b783a0fc91e28dcd74f0de77be09 416 SUPERFAMILY SSF56349 128 402 1.85E-33 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_08675 7009b783a0fc91e28dcd74f0de77be09 416 Pfam PF00589 Phage integrase family 203 395 4.1E-23 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_08675 7009b783a0fc91e28dcd74f0de77be09 416 Gene3D G3DSA:1.10.443.10 202 402 1.1E-35 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_08675 7009b783a0fc91e28dcd74f0de77be09 416 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 119 170 3.8E-6 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4R43_00015 2f9d4d52c959e44b72abc2d8f63526b7 163 SUPERFAMILY SSF54292 3 79 4.33E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_00015 2f9d4d52c959e44b72abc2d8f63526b7 163 Pfam PF01799 [2Fe-2S] binding domain 74 157 9.5E-27 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_00015 2f9d4d52c959e44b72abc2d8f63526b7 163 Gene3D G3DSA:1.10.150.120 77 163 2.9E-31 T 14-10-2018 A4R43_00015 2f9d4d52c959e44b72abc2d8f63526b7 163 SUPERFAMILY SSF47741 74 162 4.84E-27 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_00015 2f9d4d52c959e44b72abc2d8f63526b7 163 Gene3D G3DSA:3.10.20.30 1 76 2.3E-30 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_00015 2f9d4d52c959e44b72abc2d8f63526b7 163 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 52 6.8E-7 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_00015 2f9d4d52c959e44b72abc2d8f63526b7 163 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 Gene3D G3DSA:1.10.630.10 3 420 2.6E-92 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 Pfam PF00067 Cytochrome P450 16 406 3.1E-59 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 SUPERFAMILY SSF48264 14 417 2.88E-88 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00385 P450 superfamily signature 290 301 1.2E-13 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00385 P450 superfamily signature 371 382 1.2E-13 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00385 P450 superfamily signature 238 255 1.2E-13 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00385 P450 superfamily signature 362 371 1.2E-13 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00463 E-class P450 group I signature 329 353 2.3E-18 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00463 E-class P450 group I signature 361 371 2.3E-18 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00463 E-class P450 group I signature 227 244 2.3E-18 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00463 E-class P450 group I signature 247 273 2.3E-18 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 PRINTS PR00463 E-class P450 group I signature 371 394 2.3E-18 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24985 e3f84a039cdee08d78c6be67c8f10934 425 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 364 373 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_24160 024bf83fe1bf772f4a56bac3c726f910 624 Pfam PF13193 AMP-binding enzyme C-terminal domain 509 587 2.0E-26 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_24160 024bf83fe1bf772f4a56bac3c726f910 624 Gene3D G3DSA:3.30.300.30 495 623 1.4E-25 T 14-10-2018 A4R43_24160 024bf83fe1bf772f4a56bac3c726f910 624 Pfam PF00501 AMP-binding enzyme 62 499 9.9E-91 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_24160 024bf83fe1bf772f4a56bac3c726f910 624 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 58 1.0E-19 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 A4R43_24160 024bf83fe1bf772f4a56bac3c726f910 624 Gene3D G3DSA:3.40.50.12780 30 492 1.3E-110 T 14-10-2018 A4R43_24160 024bf83fe1bf772f4a56bac3c726f910 624 SUPERFAMILY SSF56801 3 621 2.22E-164 T 14-10-2018 A4R43_24160 024bf83fe1bf772f4a56bac3c726f910 624 ProSitePatterns PS00455 Putative AMP-binding domain signature. 235 246 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_19375 bf099a80f0f148e1c288a1b9c6b307fa 241 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 14 233 4.0E-110 T 14-10-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 A4R43_19375 bf099a80f0f148e1c288a1b9c6b307fa 241 SUPERFAMILY SSF49482 9 234 1.57E-74 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4R43_19375 bf099a80f0f148e1c288a1b9c6b307fa 241 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 76 104 - T 14-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 A4R43_19375 bf099a80f0f148e1c288a1b9c6b307fa 241 Gene3D G3DSA:2.60.130.10 3 235 8.4E-87 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4R43_19375 bf099a80f0f148e1c288a1b9c6b307fa 241 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 6 39 3.6E-15 T 14-10-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 A4R43_19375 bf099a80f0f148e1c288a1b9c6b307fa 241 Pfam PF00775 Dioxygenase 44 225 1.0E-53 T 14-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 A4R43_22980 c0e698e6d762d01c6f22b5b41b8800f6 299 SUPERFAMILY SSF50129 1 120 8.81E-22 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_22980 c0e698e6d762d01c6f22b5b41b8800f6 299 SMART SM00829 10 296 1.4E-8 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_22980 c0e698e6d762d01c6f22b5b41b8800f6 299 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 130 151 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A4R43_22980 c0e698e6d762d01c6f22b5b41b8800f6 299 Gene3D G3DSA:3.90.180.10 8 293 4.6E-67 T 14-10-2018 A4R43_22980 c0e698e6d762d01c6f22b5b41b8800f6 299 Gene3D G3DSA:3.40.50.720 111 266 4.6E-67 T 14-10-2018 A4R43_22980 c0e698e6d762d01c6f22b5b41b8800f6 299 SUPERFAMILY SSF51735 102 230 1.39E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22980 c0e698e6d762d01c6f22b5b41b8800f6 299 Pfam PF00107 Zinc-binding dehydrogenase 141 229 1.5E-19 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_03790 c71e0420646d6848f1e55ce33c7094f3 321 SUPERFAMILY SSF55447 218 317 1.44E-28 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily A4R43_03790 c71e0420646d6848f1e55ce33c7094f3 321 SUPERFAMILY SSF56176 1 211 2.62E-56 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_03790 c71e0420646d6848f1e55ce33c7094f3 321 SMART SM01092 218 316 1.0E-27 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_03790 c71e0420646d6848f1e55ce33c7094f3 321 Gene3D G3DSA:3.30.465.10 1 212 1.0E-73 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_03790 c71e0420646d6848f1e55ce33c7094f3 321 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 219 315 5.3E-18 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_03790 c71e0420646d6848f1e55ce33c7094f3 321 Gene3D G3DSA:3.30.390.50 215 318 4.9E-26 T 14-10-2018 A4R43_03790 c71e0420646d6848f1e55ce33c7094f3 321 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 211 3.0E-43 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4R43_09240 8eaf2993314442d143b8d34585d241d1 701 Pfam PF00270 DEAD/DEAH box helicase 27 195 6.7E-26 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_09240 8eaf2993314442d143b8d34585d241d1 701 SMART SM00487 21 236 1.2E-35 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_09240 8eaf2993314442d143b8d34585d241d1 701 Gene3D G3DSA:3.40.50.300 237 370 6.6E-27 T 14-10-2018 A4R43_09240 8eaf2993314442d143b8d34585d241d1 701 SUPERFAMILY SSF52540 71 361 2.47E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09240 8eaf2993314442d143b8d34585d241d1 701 Pfam PF00271 Helicase conserved C-terminal domain 248 347 8.6E-18 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_09240 8eaf2993314442d143b8d34585d241d1 701 Gene3D G3DSA:3.40.50.300 4 213 1.1E-45 T 14-10-2018 A4R43_09240 8eaf2993314442d143b8d34585d241d1 701 SMART SM00490 268 349 1.7E-21 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 SUPERFAMILY SSF56059 3 228 3.36E-66 T 14-10-2018 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 Gene3D G3DSA:3.40.50.261 232 387 6.7E-48 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 Pfam PF08442 ATP-grasp domain 2 194 2.2E-69 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 PIRSF PIRSF001554 1 388 6.6E-138 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 Pfam PF00549 CoA-ligase 256 378 3.5E-13 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 38.095 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 Gene3D G3DSA:3.30.470.20 2 225 2.4E-78 T 14-10-2018 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 SUPERFAMILY SSF52210 231 385 3.79E-42 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 Gene3D G3DSA:3.30.1490.20 21 96 2.4E-78 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_34465 4400a095f4d3d1cecfd9cf27e3a43e0b 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 385 8.7E-124 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_08730 8819194625e3c069ebc53ff3f4397c8e 392 Pfam PF07690 Major Facilitator Superfamily 10 353 1.8E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_08730 8819194625e3c069ebc53ff3f4397c8e 392 SUPERFAMILY SSF103473 5 388 1.96E-39 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08730 8819194625e3c069ebc53ff3f4397c8e 392 Gene3D G3DSA:1.20.1250.20 5 388 1.0E-33 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF53901 91 491 1.55E-100 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.30.559.30 1748 1980 4.8E-98 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00698 Acyl transferase domain 594 866 1.4E-52 T 14-10-2018 IPR014043 Acyl transferase A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF47336 5 109 3.53E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF47336 2492 2594 4.45E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF56801 1974 2510 1.44E-152 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00550 Phosphopantetheine attachment site 2499 2561 1.5E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00550 Phosphopantetheine attachment site 951 1015 1.4E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00550 Phosphopantetheine attachment site 11 76 4.5E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF52777 1747 1993 8.45E-44 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 95 324 1.0E-77 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 1361 1397 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SMART SM01294 949 1015 1.4E-4 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.40.47.10 90 510 3.2E-175 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.30.559.10 1580 1925 4.8E-98 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.40.640.10 1200 1461 6.7E-124 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF47336 948 1037 6.28E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2026 2420 1.3E-132 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 595 879 1.6E-90 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF52777 1581 1744 1.56E-38 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF52151 592 869 4.71E-67 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF55048 715 771 1.31E-6 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.30.300.30 2391 2482 2.1E-23 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:1.10.1200.10 2483 2571 3.5E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.30.70.3290 511 925 5.4E-136 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00668 Condensation domain 1578 1985 2.3E-68 T 14-10-2018 IPR001242 Condensation domain A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00668 Condensation domain 2581 3010 6.0E-76 T 14-10-2018 IPR001242 Condensation domain A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF52777 2759 3005 2.67E-56 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.40.366.10 593 882 5.4E-136 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2140 2151 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.30.559.30 2755 3006 2.8E-141 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.90.1150.10 1130 1548 6.7E-124 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SMART SM00825 Beta-ketoacyl synthase 97 495 4.7E-191 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 455 553 2.4E-13 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00501 AMP-binding enzyme 2005 2396 3.3E-99 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.30.559.10 2582 2945 2.8E-141 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF53383 1136 1554 2.55E-88 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 332 447 8.1E-46 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:3.40.50.12780 1991 2390 2.2E-144 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SMART SM00823 Phosphopantetheine attachment site 2498 2566 4.8E-5 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SMART SM00823 Phosphopantetheine attachment site 944 1019 0.0044 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SMART SM00823 Phosphopantetheine attachment site 9 80 2.4E-10 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:1.10.1200.10 944 1030 2.1E-11 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 SUPERFAMILY SSF52777 2583 2746 3.56E-44 T 14-10-2018 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Pfam PF00202 Aminotransferase class-III 1163 1525 3.5E-48 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 237 253 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_08150 c2a071ae5ca08907ad14aa02db63faf6 3011 Gene3D G3DSA:1.10.1200.10 1 78 2.8E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_29845 e585e5f39bc057b090c7ffeab6cf8cd2 336 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 69 204 1.1E-9 T 14-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal A4R43_29845 e585e5f39bc057b090c7ffeab6cf8cd2 336 SMART SM00342 247 330 3.4E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_29845 e585e5f39bc057b090c7ffeab6cf8cd2 336 Pfam PF12833 Helix-turn-helix domain 255 331 2.6E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_29845 e585e5f39bc057b090c7ffeab6cf8cd2 336 Gene3D G3DSA:1.10.10.60 230 335 2.0E-23 T 14-10-2018 A4R43_29845 e585e5f39bc057b090c7ffeab6cf8cd2 336 SUPERFAMILY SSF46689 285 333 1.08E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_29845 e585e5f39bc057b090c7ffeab6cf8cd2 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 1.0E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_29845 e585e5f39bc057b090c7ffeab6cf8cd2 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 1.0E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_13055 914f8753d566be7f3a12e00d17b830c3 202 Pfam PF14016 Protein of unknown function (DUF4232) 62 179 8.5E-18 T 14-10-2018 IPR025326 Protein of unknown function DUF4232 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SUPERFAMILY SSF47384 766 833 1.92E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Pfam PF00512 His Kinase A (phospho-acceptor) domain 770 831 1.6E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Gene3D G3DSA:2.10.70.100 376 421 7.1E-13 T 14-10-2018 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SMART SM00086 378 420 0.0021 T 14-10-2018 IPR001610 PAC motif A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SMART SM00086 481 525 22.0 T 14-10-2018 IPR001610 PAC motif A4R43_19630 676231822964e68fb4d3c9148aa73083 996 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 428 531 7.8E-9 T 14-10-2018 IPR000014 PAS domain A4R43_19630 676231822964e68fb4d3c9148aa73083 996 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 308 425 1.0E-6 T 14-10-2018 IPR000014 PAS domain A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Pfam PF13426 PAS domain 436 523 2.0E-7 T 14-10-2018 IPR000014 PAS domain A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SUPERFAMILY SSF52172 626 743 1.57E-28 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SUPERFAMILY SSF55785 315 421 2.79E-15 T 14-10-2018 IPR035965 PAS domain superfamily A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Gene3D G3DSA:3.30.450.20 300 372 3.8E-16 T 14-10-2018 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SUPERFAMILY SSF55785 436 534 5.96E-17 T 14-10-2018 IPR035965 PAS domain superfamily A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Pfam PF05231 MASE1 14 282 5.9E-44 T 14-10-2018 IPR007895 MASE1 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 878 982 1.9E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SMART SM00387 877 985 3.5E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_19630 676231822964e68fb4d3c9148aa73083 996 PRINTS PR00344 Bacterial sensor protein C-terminal signature 914 928 2.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 PRINTS PR00344 Bacterial sensor protein C-terminal signature 969 982 2.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 PRINTS PR00344 Bacterial sensor protein C-terminal signature 945 963 2.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Pfam PF08447 PAS fold 327 414 7.6E-15 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SMART SM00091 425 487 0.13 T 14-10-2018 IPR000014 PAS domain A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SMART SM00091 304 372 3.2 T 14-10-2018 IPR000014 PAS domain A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Gene3D G3DSA:3.30.565.10 839 983 1.4E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SMART SM00388 766 834 9.2E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SUPERFAMILY SSF55874 824 985 2.62E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_19630 676231822964e68fb4d3c9148aa73083 996 SMART SM00448 625 738 5.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Gene3D G3DSA:3.40.50.2300 624 752 1.1E-27 T 14-10-2018 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Gene3D G3DSA:1.10.287.130 764 831 3.3E-10 T 14-10-2018 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Pfam PF00072 Response regulator receiver domain 628 734 1.9E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_19630 676231822964e68fb4d3c9148aa73083 996 Gene3D G3DSA:3.30.450.20 425 544 4.5E-15 T 14-10-2018 A4R43_13645 39fbe07decc7669bd543ce052edc99d1 407 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_13645 39fbe07decc7669bd543ce052edc99d1 407 Gene3D G3DSA:3.90.1150.10 20 395 2.7E-134 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_13645 39fbe07decc7669bd543ce052edc99d1 407 Gene3D G3DSA:3.40.640.10 64 314 2.7E-134 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_13645 39fbe07decc7669bd543ce052edc99d1 407 PIRSF PIRSF000521 2 179 1.1E-8 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_13645 39fbe07decc7669bd543ce052edc99d1 407 PIRSF PIRSF000521 180 407 1.2E-25 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_13645 39fbe07decc7669bd543ce052edc99d1 407 SUPERFAMILY SSF53383 11 404 2.29E-117 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_13645 39fbe07decc7669bd543ce052edc99d1 407 Pfam PF00202 Aminotransferase class-III 23 404 8.7E-116 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_13645 39fbe07decc7669bd543ce052edc99d1 407 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 12 404 8.7E-144 T 14-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4R43_11090 88531a98071abc0ad9cdb0fac831e9f6 359 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 55 185 1.7E-59 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A4R43_11090 88531a98071abc0ad9cdb0fac831e9f6 359 Gene3D G3DSA:3.40.50.300 22 208 1.3E-45 T 14-10-2018 A4R43_11090 88531a98071abc0ad9cdb0fac831e9f6 359 PIRSF PIRSF002849 7 336 3.7E-133 T 14-10-2018 A4R43_11090 88531a98071abc0ad9cdb0fac831e9f6 359 SUPERFAMILY SSF52540 33 306 1.12E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11090 88531a98071abc0ad9cdb0fac831e9f6 359 Gene3D G3DSA:1.10.8.300 214 331 6.7E-34 T 14-10-2018 A4R43_18510 c85e4e7d1932889cb20272d73c799fbf 426 Gene3D G3DSA:1.10.3430.10 1 411 3.0E-130 T 14-10-2018 IPR029020 Ammonium/urea transporter A4R43_18510 c85e4e7d1932889cb20272d73c799fbf 426 ProSitePatterns PS01219 Ammonium transporters signature. 152 177 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 A4R43_18510 c85e4e7d1932889cb20272d73c799fbf 426 TIGRFAM TIGR00836 amt: ammonium transporter 1 397 2.6E-131 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 A4R43_18510 c85e4e7d1932889cb20272d73c799fbf 426 Pfam PF00909 Ammonium Transporter Family 1 397 1.3E-121 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A4R43_18510 c85e4e7d1932889cb20272d73c799fbf 426 SUPERFAMILY SSF111352 1 378 1.44E-109 T 14-10-2018 A4R43_20300 98c3b36742fbc02e33936b85d1258b0a 118 SUPERFAMILY SSF46955 1 115 1.14E-24 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_20300 98c3b36742fbc02e33936b85d1258b0a 118 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.5E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20300 98c3b36742fbc02e33936b85d1258b0a 118 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.5E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20300 98c3b36742fbc02e33936b85d1258b0a 118 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.5E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20300 98c3b36742fbc02e33936b85d1258b0a 118 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20300 98c3b36742fbc02e33936b85d1258b0a 118 SMART SM00422 1 69 4.7E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20300 98c3b36742fbc02e33936b85d1258b0a 118 Pfam PF13411 MerR HTH family regulatory protein 1 67 2.0E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20300 98c3b36742fbc02e33936b85d1258b0a 118 Gene3D G3DSA:1.10.1660.10 1 118 2.1E-27 T 14-10-2018 A4R43_30010 28a54003bf750addc79887918ff2ec52 533 Pfam PF00501 AMP-binding enzyme 22 431 1.8E-100 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_30010 28a54003bf750addc79887918ff2ec52 533 Gene3D G3DSA:3.30.300.310 427 532 5.3E-31 T 14-10-2018 A4R43_30010 28a54003bf750addc79887918ff2ec52 533 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_30010 28a54003bf750addc79887918ff2ec52 533 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 516 9.7E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_30010 28a54003bf750addc79887918ff2ec52 533 SUPERFAMILY SSF56801 14 529 2.09E-149 T 14-10-2018 A4R43_30010 28a54003bf750addc79887918ff2ec52 533 Gene3D G3DSA:3.40.50.12780 7 424 3.2E-114 T 14-10-2018 A4R43_30515 695ded7568fa2252b323bdc7c20890e2 281 Gene3D G3DSA:1.10.3720.10 52 264 9.6E-45 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_30515 695ded7568fa2252b323bdc7c20890e2 281 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 58 155 9.6E-19 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_30515 695ded7568fa2252b323bdc7c20890e2 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 262 6.3E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_30515 695ded7568fa2252b323bdc7c20890e2 281 SUPERFAMILY SSF161098 58 246 1.96E-35 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_19950 c28ccb4e26be8584af74a944ebd8ba26 345 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 317 9.3E-84 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_19950 c28ccb4e26be8584af74a944ebd8ba26 345 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 232 251 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4R43_19950 c28ccb4e26be8584af74a944ebd8ba26 345 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 338 56.72 T 14-10-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A4R43_19950 c28ccb4e26be8584af74a944ebd8ba26 345 Gene3D G3DSA:3.40.718.10 1 338 1.5E-124 T 14-10-2018 A4R43_19950 c28ccb4e26be8584af74a944ebd8ba26 345 SMART SM01329 2 334 4.9E-153 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_19950 c28ccb4e26be8584af74a944ebd8ba26 345 SUPERFAMILY SSF53659 2 335 9.22E-104 T 14-10-2018 A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 387 1.4E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 344 1.4E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 368 1.4E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 SMART SM00387 294 390 1.7E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 Pfam PF07730 Histidine kinase 189 254 3.3E-17 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 298 388 6.0E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 SUPERFAMILY SSF55874 264 387 1.17E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 Gene3D G3DSA:3.30.565.10 257 388 6.4E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_07655 8cdb3c1112a734903798f4f1502b609e 392 PIRSF PIRSF037434 2 392 1.1E-116 T 14-10-2018 IPR017205 Signal transduction histidine kinase, ChrS A4R43_36275 449e91f081b55368fe0889c25ddae2b9 140 Pfam PF14087 Domain of unknown function (DUF4267) 14 116 3.5E-23 T 14-10-2018 IPR025363 Protein of unknown function DUF4267 A4R43_36465 87daa8b488d77798271b072a8c715430 217 SUPERFAMILY SSF46785 10 81 8.35E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_36465 87daa8b488d77798271b072a8c715430 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 6.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_36465 87daa8b488d77798271b072a8c715430 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 6.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_36465 87daa8b488d77798271b072a8c715430 217 Gene3D G3DSA:1.20.120.530 81 217 6.9E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_36465 87daa8b488d77798271b072a8c715430 217 SMART SM00895 87 210 1.3E-8 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_36465 87daa8b488d77798271b072a8c715430 217 SMART SM00345 19 77 3.3E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_36465 87daa8b488d77798271b072a8c715430 217 Gene3D G3DSA:1.10.10.10 2 78 2.3E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36465 87daa8b488d77798271b072a8c715430 217 Pfam PF07729 FCD domain 91 207 1.2E-16 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_36465 87daa8b488d77798271b072a8c715430 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 2.2E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_36465 87daa8b488d77798271b072a8c715430 217 SUPERFAMILY SSF48008 82 216 1.41E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_32625 0f1727c23f350e7a276c1d42f76517aa 163 Gene3D G3DSA:1.10.10.10 76 158 8.2E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32625 0f1727c23f350e7a276c1d42f76517aa 163 Gene3D G3DSA:1.10.1740.10 1 69 5.2E-6 T 14-10-2018 A4R43_32625 0f1727c23f350e7a276c1d42f76517aa 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 152 2.7E-14 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_32625 0f1727c23f350e7a276c1d42f76517aa 163 SUPERFAMILY SSF88659 79 156 3.88E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_32625 0f1727c23f350e7a276c1d42f76517aa 163 SUPERFAMILY SSF88946 2 77 5.49E-10 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_32625 0f1727c23f350e7a276c1d42f76517aa 163 Pfam PF13412 Winged helix-turn-helix DNA-binding 109 138 2.9E-5 T 14-10-2018 A4R43_32625 0f1727c23f350e7a276c1d42f76517aa 163 Pfam PF04542 Sigma-70 region 2 3 69 4.9E-6 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_35920 3e038ba4cbd3b32ee56bfd113d3c309d 231 Pfam PF01903 CbiX 122 210 1.0E-8 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A4R43_35920 3e038ba4cbd3b32ee56bfd113d3c309d 231 Pfam PF01903 CbiX 7 103 5.8E-16 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A4R43_35920 3e038ba4cbd3b32ee56bfd113d3c309d 231 Gene3D G3DSA:3.40.50.1400 1 111 2.0E-24 T 14-10-2018 A4R43_35920 3e038ba4cbd3b32ee56bfd113d3c309d 231 SUPERFAMILY SSF53800 2 218 1.09E-31 T 14-10-2018 A4R43_35920 3e038ba4cbd3b32ee56bfd113d3c309d 231 Gene3D G3DSA:3.40.50.1400 112 220 2.3E-18 T 14-10-2018 A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 Pfam PF03466 LysR substrate binding domain 89 288 6.1E-39 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.1E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 SUPERFAMILY SSF46785 2 84 2.58E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 Gene3D G3DSA:3.40.190.10 163 266 5.9E-56 T 14-10-2018 A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 Gene3D G3DSA:3.40.190.10 88 284 5.9E-56 T 14-10-2018 A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 Gene3D G3DSA:1.10.10.10 1 84 2.7E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02980 42470aeca51a24a04fc4fe61fa7492a6 299 SUPERFAMILY SSF53850 91 295 1.59E-34 T 14-10-2018 A4R43_40625 ca2bca16e30e10b19196d76cfcd667fa 395 Gene3D G3DSA:3.30.920.50 234 348 4.1E-118 T 14-10-2018 A4R43_40625 ca2bca16e30e10b19196d76cfcd667fa 395 Gene3D G3DSA:2.60.110.10 39 374 4.1E-118 T 14-10-2018 IPR037176 Osmotin/thaumatin-like superfamily A4R43_40625 ca2bca16e30e10b19196d76cfcd667fa 395 Pfam PF16483 Beta-1,3-glucanase 34 391 2.8E-101 T 14-10-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 A4R43_08255 c1c24050ca6ee4465b4d29f449746b6e 442 Gene3D G3DSA:1.20.1250.20 22 431 7.6E-53 T 14-10-2018 A4R43_08255 c1c24050ca6ee4465b4d29f449746b6e 442 SUPERFAMILY SSF103473 22 426 5.36E-60 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08255 c1c24050ca6ee4465b4d29f449746b6e 442 Pfam PF07690 Major Facilitator Superfamily 26 373 3.3E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_34585 c86b6aa3ebb5596614b4c3539b9ce285 192 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 5 189 6.4E-90 T 14-10-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD A4R43_34585 c86b6aa3ebb5596614b4c3539b9ce285 192 SUPERFAMILY SSF48150 13 144 2.44E-14 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4R43_34585 c86b6aa3ebb5596614b4c3539b9ce285 192 Gene3D G3DSA:1.10.340.30 13 139 2.2E-6 T 14-10-2018 A4R43_34585 c86b6aa3ebb5596614b4c3539b9ce285 192 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 148 1.5E-13 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 2.2E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 Gene3D G3DSA:3.50.50.60 118 240 2.5E-117 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 SUPERFAMILY SSF51905 8 306 2.7E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 Gene3D G3DSA:3.50.50.60 9 300 2.5E-117 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.0E-35 T 14-10-2018 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 5.0E-35 T 14-10-2018 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.0E-35 T 14-10-2018 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.0E-35 T 14-10-2018 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 5.0E-35 T 14-10-2018 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 295 8.3E-47 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_30490 090760daf12a841a1dd9f8c48f7f023e 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 306 6.4E-121 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 Pfam PF12833 Helix-turn-helix domain 238 316 2.7E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 SUPERFAMILY SSF46689 216 265 6.57E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 SUPERFAMILY SSF52317 8 197 1.26E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 SUPERFAMILY SSF46689 269 318 7.83E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 Pfam PF01965 DJ-1/PfpI family 8 176 1.6E-15 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 Gene3D G3DSA:1.10.10.60 212 318 2.2E-23 T 14-10-2018 A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 SMART SM00342 232 315 1.7E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00120 d2f20a4100ab4e5b413fb815ba2cc1e1 326 Gene3D G3DSA:3.40.50.880 7 210 6.5E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_08875 b4c07626c044f922f93977bc2c45aa5c 521 Gene3D G3DSA:1.20.1720.10 19 250 1.2E-36 T 14-10-2018 A4R43_08875 b4c07626c044f922f93977bc2c45aa5c 521 Pfam PF07690 Major Facilitator Superfamily 26 413 1.6E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_08875 b4c07626c044f922f93977bc2c45aa5c 521 Gene3D G3DSA:1.20.1250.20 270 430 4.3E-15 T 14-10-2018 A4R43_08875 b4c07626c044f922f93977bc2c45aa5c 521 SUPERFAMILY SSF103473 6 509 1.11E-62 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18370 d3c2a1d7957be2a9184a752dcac24227 281 SUPERFAMILY SSF54593 18 133 3.95E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_18370 d3c2a1d7957be2a9184a752dcac24227 281 SUPERFAMILY SSF54593 150 261 5.92E-14 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_18370 d3c2a1d7957be2a9184a752dcac24227 281 Gene3D G3DSA:3.10.180.10 11 134 2.6E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_18370 d3c2a1d7957be2a9184a752dcac24227 281 Gene3D G3DSA:3.10.180.10 140 264 5.9E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 Pfam PF01612 3'-5' exonuclease 33 197 8.2E-34 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 Gene3D G3DSA:3.30.420.10 15 218 4.6E-71 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 Pfam PF00570 HRDC domain 240 304 1.3E-11 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 SMART SM00474 30 197 1.0E-38 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 Gene3D G3DSA:1.10.150.80 221 318 1.6E-24 T 14-10-2018 A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 SUPERFAMILY SSF53098 19 234 9.11E-55 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 SUPERFAMILY SSF47819 217 327 1.05E-22 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 Gene3D G3DSA:1.10.150.80 325 417 6.7E-28 T 14-10-2018 A4R43_13870 a6b3dcc4685ba3ffa72e069195bb8259 418 SMART SM00341 236 316 1.0E-11 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 264 307 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 311 1.1E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 280 295 1.1E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 Pfam PF14525 AraC-binding-like domain 17 195 8.3E-29 T 14-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 Pfam PF12833 Helix-turn-helix domain 233 312 1.5E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 SMART SM00342 227 311 1.5E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 SUPERFAMILY SSF46689 263 312 3.36E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 SUPERFAMILY SSF46689 211 260 8.96E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00760 cebd198421ef97199fbfa66b504101cf 313 Gene3D G3DSA:1.10.10.60 211 313 2.7E-29 T 14-10-2018 A4R43_00240 3059eb5a49111461ccea9ea7a3c0dccd 254 PIRSF PIRSF015582 1 253 4.3E-59 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like A4R43_00240 3059eb5a49111461ccea9ea7a3c0dccd 254 Gene3D G3DSA:3.20.20.60 1 254 2.3E-67 T 14-10-2018 A4R43_00240 3059eb5a49111461ccea9ea7a3c0dccd 254 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 3 190 2.8E-25 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_00240 3059eb5a49111461ccea9ea7a3c0dccd 254 SUPERFAMILY SSF51621 2 199 2.23E-46 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_23370 8109711adb95bf04215edfc419c70242 321 Gene3D G3DSA:1.10.240.10 180 288 6.2E-97 T 14-10-2018 A4R43_23370 8109711adb95bf04215edfc419c70242 321 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 60 79 7.7E-14 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_23370 8109711adb95bf04215edfc419c70242 321 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 13 29 7.7E-14 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_23370 8109711adb95bf04215edfc419c70242 321 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 189 199 7.7E-14 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_23370 8109711adb95bf04215edfc419c70242 321 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 136 157 7.7E-14 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_23370 8109711adb95bf04215edfc419c70242 321 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 319 5.9E-71 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4R43_23370 8109711adb95bf04215edfc419c70242 321 Pfam PF00579 tRNA synthetases class I (W and Y) 5 275 1.9E-51 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_23370 8109711adb95bf04215edfc419c70242 321 SUPERFAMILY SSF52374 4 318 2.66E-68 T 14-10-2018 A4R43_23370 8109711adb95bf04215edfc419c70242 321 Gene3D G3DSA:3.40.50.620 4 318 6.2E-97 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00065 631 780 4.6E-8 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:3.30.450.40 619 774 7.6E-21 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF52172 1157 1244 1.42E-7 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF58104 115 295 5.75E-13 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF52172 1280 1400 1.71E-37 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00388 851 919 2.8E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Pfam PF00072 Response regulator receiver domain 1283 1395 1.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:1.10.8.500 98 154 8.4E-10 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:1.10.8.500 463 521 2.1E-8 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:1.10.8.500 557 618 1.1E-9 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:1.10.8.500 190 246 5.7E-9 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1032 1042 2.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1049 1067 2.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1014 1028 2.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1073 1086 2.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:3.40.50.2300 1117 1252 1.6E-7 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:1.10.287.130 817 917 7.1E-26 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 967 1087 3.9E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00304 463 515 4.0E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00304 95 147 1.2E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00304 555 607 5.5E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00304 187 239 1.2E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00304 3 55 4.6E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00304 371 423 3.6E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00304 279 331 1.6E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:3.40.50.12740 1280 1401 2.7E-41 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF58104 299 478 1.05E-11 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF47384 836 921 9.02E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF58104 23 152 3.4E-11 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Pfam PF00512 His Kinase A (phospho-acceptor) domain 852 919 6.3E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:2.60.120.260 1 92 7.8E-9 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:2.60.120.260 275 367 6.6E-10 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:2.60.120.260 368 462 9.1E-8 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00387 966 1089 6.2E-39 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Gene3D G3DSA:3.30.565.10 918 1090 3.1E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF55781 594 764 1.31E-29 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SMART SM00448 1281 1395 6.1E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 Pfam PF13185 GAF domain 630 764 3.2E-17 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF58104 483 607 1.26E-11 T 14-10-2018 A4R43_05735 f37d23105e6856337a359923fae9febe 1401 SUPERFAMILY SSF55874 908 1093 7.73E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_32175 5e0958356992e114e1d77bcbda98b2e7 118 SUPERFAMILY SSF46785 14 105 2.34E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_32175 5e0958356992e114e1d77bcbda98b2e7 118 Gene3D G3DSA:1.10.10.10 13 115 5.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32175 5e0958356992e114e1d77bcbda98b2e7 118 Pfam PF01022 Bacterial regulatory protein, arsR family 14 62 1.1E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_32175 5e0958356992e114e1d77bcbda98b2e7 118 SMART SM00418 11 89 1.5E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_26275 47e7ada9c4c0d9f2591177a4bedf51c8 130 Pfam PF06339 Ectoine synthase 1 126 2.9E-57 T 14-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 A4R43_26275 47e7ada9c4c0d9f2591177a4bedf51c8 130 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 36.178 T 14-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 A4R43_26275 47e7ada9c4c0d9f2591177a4bedf51c8 130 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 6.0E-40 T 14-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 A4R43_26275 47e7ada9c4c0d9f2591177a4bedf51c8 130 SUPERFAMILY SSF51182 18 127 4.45E-19 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_26275 47e7ada9c4c0d9f2591177a4bedf51c8 130 Gene3D G3DSA:2.60.120.10 1 115 8.5E-41 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_27620 7e0af9af0a532b160ddf53c39009365f 822 SUPERFAMILY SSF56219 488 798 1.05E-31 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_27620 7e0af9af0a532b160ddf53c39009365f 822 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 495 788 1.6E-9 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4R43_27620 7e0af9af0a532b160ddf53c39009365f 822 Gene3D G3DSA:3.60.10.10 492 795 2.6E-33 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 SUPERFAMILY SSF51735 5 247 3.08E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 Gene3D G3DSA:3.40.50.720 1 247 5.6E-74 T 14-10-2018 A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.6E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.6E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.6E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 5.9E-59 T 14-10-2018 A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 8.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 8.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05285 41b5b755d9ff12e638cfef11f68f2bb0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21040 57d530a3681db8f8e7d67f74ecaad945 619 Gene3D G3DSA:3.40.50.12780 345 472 2.0E-32 T 14-10-2018 A4R43_21040 57d530a3681db8f8e7d67f74ecaad945 619 Gene3D G3DSA:3.30.300.30 476 607 1.2E-5 T 14-10-2018 A4R43_21040 57d530a3681db8f8e7d67f74ecaad945 619 SUPERFAMILY SSF56801 12 612 3.92E-110 T 14-10-2018 A4R43_21040 57d530a3681db8f8e7d67f74ecaad945 619 Pfam PF00501 AMP-binding enzyme 21 479 1.4E-82 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_21040 57d530a3681db8f8e7d67f74ecaad945 619 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_21040 57d530a3681db8f8e7d67f74ecaad945 619 Gene3D G3DSA:3.40.50.12780 4 344 1.0E-45 T 14-10-2018 A4R43_38350 fbba008291a6655bb0e501a3e9095304 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.5E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_38350 fbba008291a6655bb0e501a3e9095304 304 SUPERFAMILY SSF53850 90 295 2.05E-34 T 14-10-2018 A4R43_38350 fbba008291a6655bb0e501a3e9095304 304 Gene3D G3DSA:3.40.190.10 92 280 4.1E-42 T 14-10-2018 A4R43_38350 fbba008291a6655bb0e501a3e9095304 304 Pfam PF03466 LysR substrate binding domain 88 292 3.7E-39 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_38350 fbba008291a6655bb0e501a3e9095304 304 Gene3D G3DSA:1.10.10.10 1 89 3.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38350 fbba008291a6655bb0e501a3e9095304 304 Gene3D G3DSA:3.40.190.10 170 266 4.1E-42 T 14-10-2018 A4R43_38350 fbba008291a6655bb0e501a3e9095304 304 SUPERFAMILY SSF46785 2 111 1.69E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_24125 ea40c3332638fecff6cabfc58c7a07d2 319 Gene3D G3DSA:3.40.50.720 114 260 3.4E-87 T 14-10-2018 A4R43_24125 ea40c3332638fecff6cabfc58c7a07d2 319 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 68 8.2E-5 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_24125 ea40c3332638fecff6cabfc58c7a07d2 319 SUPERFAMILY SSF51735 103 282 1.75E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_24125 ea40c3332638fecff6cabfc58c7a07d2 319 Pfam PF00107 Zinc-binding dehydrogenase 142 259 2.4E-30 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_24125 ea40c3332638fecff6cabfc58c7a07d2 319 SUPERFAMILY SSF50129 1 131 4.72E-32 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_24125 ea40c3332638fecff6cabfc58c7a07d2 319 Gene3D G3DSA:3.90.180.10 9 313 3.4E-87 T 14-10-2018 A4R43_24125 ea40c3332638fecff6cabfc58c7a07d2 319 SMART SM00829 10 315 2.5E-24 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_19245 daf48c4886a561ede73d140ff68265d1 289 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 20 267 1.4E-87 T 14-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A4R43_19245 daf48c4886a561ede73d140ff68265d1 289 Gene3D G3DSA:2.60.120.10 22 125 6.5E-83 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_19245 daf48c4886a561ede73d140ff68265d1 289 Gene3D G3DSA:2.60.120.10 126 266 6.5E-83 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_19245 daf48c4886a561ede73d140ff68265d1 289 Pfam PF04962 KduI/IolB family 17 266 2.3E-84 T 14-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 A4R43_19245 daf48c4886a561ede73d140ff68265d1 289 SUPERFAMILY SSF51182 19 250 3.68E-56 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_19245 daf48c4886a561ede73d140ff68265d1 289 PIRSF PIRSF036628 1 272 6.1E-85 T 14-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 SUPERFAMILY SSF56112 183 401 3.78E-25 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 SMART SM01260 453 758 2.7E-6 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 Gene3D G3DSA:1.50.10.10 574 748 2.1E-6 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 Gene3D G3DSA:3.30.200.20 180 260 2.3E-27 T 14-10-2018 A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 Pfam PF00069 Protein kinase domain 183 365 8.9E-11 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 SUPERFAMILY SSF158745 457 757 7.85E-24 T 14-10-2018 A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 SMART SM00220 179 420 1.8E-5 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 Gene3D G3DSA:1.10.510.10 261 409 2.3E-27 T 14-10-2018 A4R43_37405 fffe655440f0c8d6e91059b1f9186e43 775 Pfam PF05147 Lanthionine synthetase C-like protein 530 747 3.0E-13 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 SUPERFAMILY SSF48264 3 366 3.01E-89 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 238 249 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 55 66 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 119 134 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 315 326 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 257 284 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 156 178 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 285 300 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 102 118 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00359 B-class P450 signature 306 315 2.6E-37 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00385 P450 superfamily signature 238 249 6.9E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00385 P450 superfamily signature 306 315 6.9E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00385 P450 superfamily signature 203 220 6.9E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 PRINTS PR00385 P450 superfamily signature 315 326 6.9E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 Gene3D G3DSA:1.10.630.10 1 367 7.7E-133 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 Pfam PF00067 Cytochrome P450 169 227 3.1E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 Pfam PF00067 Cytochrome P450 239 336 1.8E-16 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40390 74403a8e66245ce5bf2cb747ebf5bedb 367 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 308 317 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_40695 39dec4fc2d4a4cf9a42b32b244c020aa 378 Pfam PF00480 ROK family 85 366 4.3E-47 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_40695 39dec4fc2d4a4cf9a42b32b244c020aa 378 SUPERFAMILY SSF53067 84 368 3.03E-47 T 14-10-2018 A4R43_40695 39dec4fc2d4a4cf9a42b32b244c020aa 378 Gene3D G3DSA:1.10.10.10 3 78 3.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40695 39dec4fc2d4a4cf9a42b32b244c020aa 378 Pfam PF12802 MarR family 16 65 1.9E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40695 39dec4fc2d4a4cf9a42b32b244c020aa 378 SUPERFAMILY SSF46785 9 72 1.49E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40695 39dec4fc2d4a4cf9a42b32b244c020aa 378 Gene3D G3DSA:3.30.420.40 90 363 3.1E-69 T 14-10-2018 A4R43_40695 39dec4fc2d4a4cf9a42b32b244c020aa 378 Gene3D G3DSA:3.30.420.40 200 353 3.1E-69 T 14-10-2018 A4R43_24135 35f0fb203fa3024669777d027dff7a93 281 PIRSF PIRSF005917 1 279 1.9E-89 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A4R43_24135 35f0fb203fa3024669777d027dff7a93 281 SUPERFAMILY SSF53790 5 224 3.93E-71 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4R43_24135 35f0fb203fa3024669777d027dff7a93 281 Gene3D G3DSA:3.40.1010.10 1 115 9.6E-32 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4R43_24135 35f0fb203fa3024669777d027dff7a93 281 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 6 226 32.955 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A4R43_24135 35f0fb203fa3024669777d027dff7a93 281 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 7 274 1.4E-61 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A4R43_24135 35f0fb203fa3024669777d027dff7a93 281 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 209 2.6E-27 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4R43_24135 35f0fb203fa3024669777d027dff7a93 281 Gene3D G3DSA:3.30.950.10 116 230 2.9E-40 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4R43_25655 f5a303f07b9a3e48577f8d2a35500fec 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.2E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25655 f5a303f07b9a3e48577f8d2a35500fec 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.2E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25655 f5a303f07b9a3e48577f8d2a35500fec 199 SUPERFAMILY SSF48498 80 175 2.34E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_25655 f5a303f07b9a3e48577f8d2a35500fec 199 SUPERFAMILY SSF46689 5 74 1.9E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25655 f5a303f07b9a3e48577f8d2a35500fec 199 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 85 174 6.6E-13 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_25655 f5a303f07b9a3e48577f8d2a35500fec 199 Gene3D G3DSA:1.10.357.10 1 193 2.5E-45 T 14-10-2018 A4R43_25655 f5a303f07b9a3e48577f8d2a35500fec 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.1E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 SUPERFAMILY SSF56053 1 82 2.4E-26 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 37.719 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 SUPERFAMILY SSF56053 83 177 4.32E-35 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 Gene3D G3DSA:3.90.930.12 1 82 1.2E-30 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 PIRSF PIRSF002162 1 177 4.1E-44 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 Gene3D G3DSA:3.90.930.12 83 178 1.9E-39 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.4E-74 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 8.9E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 8.9E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 8.9E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 Pfam PF00347 Ribosomal protein L6 11 82 6.7E-18 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33915 5b095756e3e5386f2defb6ffaece180f 178 Pfam PF00347 Ribosomal protein L6 91 164 8.7E-18 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_25835 1755596a94123b2beadff84e78c93534 128 SMART SM00357 3 65 1.2E-19 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 A4R43_25835 1755596a94123b2beadff84e78c93534 128 SUPERFAMILY SSF50249 3 65 7.1E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_25835 1755596a94123b2beadff84e78c93534 128 PRINTS PR00050 Cold shock protein signature 4 19 7.3E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_25835 1755596a94123b2beadff84e78c93534 128 PRINTS PR00050 Cold shock protein signature 38 56 7.3E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_25835 1755596a94123b2beadff84e78c93534 128 PRINTS PR00050 Cold shock protein signature 24 33 7.3E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_25835 1755596a94123b2beadff84e78c93534 128 Pfam PF00313 'Cold-shock' DNA-binding domain 3 63 4.3E-14 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_25835 1755596a94123b2beadff84e78c93534 128 Gene3D G3DSA:2.40.50.140 2 64 7.9E-18 T 14-10-2018 A4R43_13315 43cc2706c7d61453c5fb5cfb0fccd439 305 SUPERFAMILY SSF53850 57 288 5.24E-52 T 14-10-2018 A4R43_13315 43cc2706c7d61453c5fb5cfb0fccd439 305 Gene3D G3DSA:3.40.190.10 158 251 5.1E-58 T 14-10-2018 A4R43_13315 43cc2706c7d61453c5fb5cfb0fccd439 305 Gene3D G3DSA:3.40.190.10 60 286 5.1E-58 T 14-10-2018 A4R43_13315 43cc2706c7d61453c5fb5cfb0fccd439 305 SMART SM00062 67 293 1.9E-47 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_13315 43cc2706c7d61453c5fb5cfb0fccd439 305 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 68 288 1.1E-42 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_13795 6a74e7c884af61fad619b83abea3696e 300 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 16 248 2.5E-33 T 14-10-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 Pfam PF01551 Peptidase family M23 69 162 2.1E-26 T 14-10-2018 IPR016047 Peptidase M23 A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 Pfam PF01471 Putative peptidoglycan binding domain 192 246 8.7E-13 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 Pfam PF01471 Putative peptidoglycan binding domain 260 311 2.5E-10 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 SUPERFAMILY SSF47090 183 248 7.59E-17 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 SUPERFAMILY SSF47090 249 311 2.88E-13 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 Gene3D G3DSA:2.70.70.10 28 176 1.2E-37 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 Gene3D G3DSA:1.10.101.10 248 313 9.8E-16 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 Gene3D G3DSA:1.10.101.10 184 247 4.9E-16 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_41010 ba035dd25c8e311592398b907c02fdf9 313 SUPERFAMILY SSF51261 38 173 5.75E-35 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 SUPERFAMILY SSF51703 500 1075 4.71E-152 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 Pfam PF03308 ArgK protein 182 395 2.4E-40 T 14-10-2018 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 708 1078 4.1E-96 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 Gene3D G3DSA:3.40.50.280 7 150 6.4E-55 T 14-10-2018 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 Gene3D G3DSA:3.20.20.240 536 1075 9.2E-184 T 14-10-2018 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 SUPERFAMILY SSF52242 6 143 7.85E-40 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 Pfam PF02310 B12 binding domain 13 105 4.0E-10 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 Pfam PF01642 Methylmalonyl-CoA mutase 542 1073 2.8E-141 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 SUPERFAMILY SSF52540 152 402 4.99E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 Gene3D G3DSA:3.40.50.300 188 402 3.1E-57 T 14-10-2018 A4R43_16160 360d6c95f7674dd497a62482a6a17823 1079 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 11 1079 16.63 T 14-10-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 SMART SM00926 39 93 0.0013 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 Gene3D G3DSA:2.20.25.90 35 94 2.4E-5 T 14-10-2018 A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 SUPERFAMILY SSF50692 623 768 7.67E-39 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 Pfam PF00384 Molybdopterin oxidoreductase 96 520 4.3E-63 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 SUPERFAMILY SSF53706 40 596 1.7E-156 T 14-10-2018 A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 Gene3D G3DSA:3.40.50.740 101 578 3.1E-160 T 14-10-2018 A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 Pfam PF01568 Molydopterin dinucleotide binding domain 649 760 3.2E-27 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 Gene3D G3DSA:2.40.40.20 639 767 4.2E-41 T 14-10-2018 A4R43_36455 8c674221a5d3aaac01356e7a60ed8b25 770 Gene3D G3DSA:3.40.228.10 174 375 3.1E-160 T 14-10-2018 A4R43_09890 31a374bfc16b5983a7b24452799dfe16 258 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_09890 31a374bfc16b5983a7b24452799dfe16 258 SUPERFAMILY SSF52540 4 229 8.88E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09890 31a374bfc16b5983a7b24452799dfe16 258 SMART SM00382 29 225 8.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_09890 31a374bfc16b5983a7b24452799dfe16 258 Pfam PF00005 ABC transporter 22 169 4.2E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_09890 31a374bfc16b5983a7b24452799dfe16 258 Gene3D G3DSA:3.40.50.300 4 254 4.9E-68 T 14-10-2018 A4R43_03905 1803169508086bc03ae394c085d82f71 208 Gene3D G3DSA:3.40.430.10 2 204 3.8E-44 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_03905 1803169508086bc03ae394c085d82f71 208 Pfam PF01872 RibD C-terminal domain 7 200 3.9E-33 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_03905 1803169508086bc03ae394c085d82f71 208 SUPERFAMILY SSF53597 29 203 3.93E-26 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_31660 f2c89fac2daa1d9f876a38c9ea096310 310 SUPERFAMILY SSF51679 1 304 1.65E-54 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_31660 f2c89fac2daa1d9f876a38c9ea096310 310 Gene3D G3DSA:3.20.20.30 1 305 2.2E-54 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_31660 f2c89fac2daa1d9f876a38c9ea096310 310 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 20 284 2.3E-108 T 14-10-2018 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted A4R43_31660 f2c89fac2daa1d9f876a38c9ea096310 310 Pfam PF00296 Luciferase-like monooxygenase 11 280 1.3E-45 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_38185 fdd01cc0f72656b46d1acc09246944f5 319 Gene3D G3DSA:3.20.20.100 1 297 4.7E-68 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_38185 fdd01cc0f72656b46d1acc09246944f5 319 Pfam PF00248 Aldo/keto reductase family 7 291 4.5E-48 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_38185 fdd01cc0f72656b46d1acc09246944f5 319 SUPERFAMILY SSF51430 2 304 6.68E-64 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_23935 cae24383dcf9aa8824ddf22e33673075 190 Gene3D G3DSA:2.60.120.10 79 181 9.1E-15 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_23935 cae24383dcf9aa8824ddf22e33673075 190 Gene3D G3DSA:1.10.260.40 5 76 1.1E-17 T 14-10-2018 A4R43_23935 cae24383dcf9aa8824ddf22e33673075 190 SUPERFAMILY SSF51182 65 173 1.63E-23 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_23935 cae24383dcf9aa8824ddf22e33673075 190 Pfam PF07883 Cupin domain 108 174 1.4E-15 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_23935 cae24383dcf9aa8824ddf22e33673075 190 SMART SM00530 14 69 1.8E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_23935 cae24383dcf9aa8824ddf22e33673075 190 Pfam PF01381 Helix-turn-helix 15 69 5.6E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_23935 cae24383dcf9aa8824ddf22e33673075 190 SUPERFAMILY SSF47413 6 74 8.16E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR00379 Intein signature 1328 1337 5.3E-15 T 14-10-2018 IPR006142 Intein GO:0016539 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR00379 Intein signature 969 982 5.3E-15 T 14-10-2018 IPR006142 Intein GO:0016539 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR00379 Intein signature 1041 1053 5.3E-15 T 14-10-2018 IPR006142 Intein GO:0016539 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR00379 Intein signature 1146 1158 5.3E-15 T 14-10-2018 IPR006142 Intein GO:0016539 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR00379 Intein signature 1310 1327 5.3E-15 T 14-10-2018 IPR006142 Intein GO:0016539 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR00379 Intein signature 1172 1187 5.3E-15 T 14-10-2018 IPR006142 Intein GO:0016539 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR01183 Ribonucleotide reductase large chain signature 714 725 1.1E-9 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR01183 Ribonucleotide reductase large chain signature 786 808 1.1E-9 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR01183 Ribonucleotide reductase large chain signature 587 606 1.1E-9 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 PRINTS PR01183 Ribonucleotide reductase large chain signature 748 771 1.1E-9 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SUPERFAMILY SSF55608 361 466 6.23E-13 T 14-10-2018 IPR027434 Homing endonuclease A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1313 1334 1.8E-6 T 14-10-2018 IPR030934 Intein C-terminal splicing region A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SUPERFAMILY SSF51294 906 1333 3.34E-29 T 14-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Pfam PF14890 Intein splicing domain 953 1333 1.6E-9 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Pfam PF02867 Ribonucleotide reductase, barrel domain 1334 1474 5.0E-29 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 511 908 2.4E-126 T 14-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Gene3D G3DSA:3.10.28.10 1037 1209 2.4E-19 T 14-10-2018 IPR027434 Homing endonuclease A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 51 134 1.3E-20 T 14-10-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Gene3D G3DSA:3.20.70.20 1332 1490 2.3E-48 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Gene3D G3DSA:3.20.70.20 60 166 6.8E-9 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Gene3D G3DSA:3.20.70.20 491 911 3.4E-124 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Pfam PF14528 LAGLIDADG-like domain 1145 1217 7.2E-9 T 14-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Pfam PF14528 LAGLIDADG-like domain 374 454 8.5E-13 T 14-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Gene3D G3DSA:2.170.16.10 167 297 1.5E-8 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SUPERFAMILY SSF55608 1139 1229 5.21E-9 T 14-10-2018 IPR027434 Homing endonuclease A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Pfam PF02867 Ribonucleotide reductase, barrel domain 513 907 5.8E-102 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Gene3D G3DSA:2.170.16.10 912 1017 1.6E-8 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SMART SM00306 155 252 2.1E-6 T 14-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SMART SM00306 905 1006 9.6E-6 T 14-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SMART SM00305 476 519 1.2 T 14-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SMART SM00305 1294 1339 0.043 T 14-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SUPERFAMILY SSF51998 1333 1486 4.88E-24 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Gene3D G3DSA:2.170.16.10 1263 1331 1.6E-8 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 157 225 2.2E-7 T 14-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SUPERFAMILY SSF51998 512 906 1.65E-99 T 14-10-2018 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 SUPERFAMILY SSF51294 157 513 5.1E-26 T 14-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_16805 3cea1e23d9390bc63934f980ced36b49 1716 Gene3D G3DSA:3.10.28.10 359 472 5.1E-19 T 14-10-2018 IPR027434 Homing endonuclease A4R43_19780 91329732a9be538c1c429be4a4e2f268 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 3.8E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_19780 91329732a9be538c1c429be4a4e2f268 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 3.8E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_19780 91329732a9be538c1c429be4a4e2f268 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 3.8E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_19780 91329732a9be538c1c429be4a4e2f268 251 Gene3D G3DSA:3.40.50.1820 2 250 3.3E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_19780 91329732a9be538c1c429be4a4e2f268 251 SUPERFAMILY SSF53474 7 246 4.77E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_19780 91329732a9be538c1c429be4a4e2f268 251 Pfam PF12697 Alpha/beta hydrolase family 34 242 1.8E-15 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_19935 0144f91fe39f63da3419577fd8ec35a1 417 Pfam PF01494 FAD binding domain 7 327 5.7E-60 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_19935 0144f91fe39f63da3419577fd8ec35a1 417 Gene3D G3DSA:3.50.50.60 2 360 6.3E-59 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_19935 0144f91fe39f63da3419577fd8ec35a1 417 SUPERFAMILY SSF51905 6 361 1.35E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_19935 0144f91fe39f63da3419577fd8ec35a1 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 7.9E-19 T 14-10-2018 A4R43_19935 0144f91fe39f63da3419577fd8ec35a1 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 7.9E-19 T 14-10-2018 A4R43_19935 0144f91fe39f63da3419577fd8ec35a1 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 7.9E-19 T 14-10-2018 A4R43_19935 0144f91fe39f63da3419577fd8ec35a1 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 7.9E-19 T 14-10-2018 A4R43_14620 51e17e72fa5cc136836d797e5e7f35dc 472 SUPERFAMILY SSF53743 2 312 5.36E-80 T 14-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A4R43_14620 51e17e72fa5cc136836d797e5e7f35dc 472 Gene3D G3DSA:3.40.275.10 157 298 1.5E-30 T 14-10-2018 IPR038392 L-fucose isomerase, domain 2 superfamily KEGG: 00051+5.3.1.25 A4R43_14620 51e17e72fa5cc136836d797e5e7f35dc 472 Gene3D G3DSA:3.20.14.10 331 467 8.7E-6 T 14-10-2018 IPR038393 L-fucose isomerase, domain 3 superfamily KEGG: 00051+5.3.1.25 A4R43_14620 51e17e72fa5cc136836d797e5e7f35dc 472 SUPERFAMILY SSF50443 316 465 4.71E-6 T 14-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal A4R43_14620 51e17e72fa5cc136836d797e5e7f35dc 472 Pfam PF02952 L-fucose isomerase, C-terminal domain 332 468 1.0E-36 T 14-10-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 A4R43_14620 51e17e72fa5cc136836d797e5e7f35dc 472 Pfam PF07881 L-fucose isomerase, first N-terminal domain 3 155 1.6E-18 T 14-10-2018 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 A4R43_14620 51e17e72fa5cc136836d797e5e7f35dc 472 Pfam PF07882 L-fucose isomerase, second N-terminal domain 254 311 1.9E-9 T 14-10-2018 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 Gene3D G3DSA:3.40.50.300 1150 1337 1.5E-22 T 14-10-2018 A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 SUPERFAMILY SSF52540 355 1316 2.86E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 Gene3D G3DSA:3.40.960.10 1366 1464 3.6E-14 T 14-10-2018 A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 Pfam PF13086 AAA domain 358 519 6.5E-12 T 14-10-2018 A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 SUPERFAMILY SSF52540 377 645 1.89E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 Gene3D G3DSA:3.40.50.300 326 524 1.7E-21 T 14-10-2018 A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 Gene3D G3DSA:3.40.50.300 900 1143 3.3E-9 T 14-10-2018 A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 SUPERFAMILY SSF52980 1361 1465 4.02E-11 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4R43_09275 51dfda60f303fffa3f24da48be551e40 1698 Pfam PF13087 AAA domain 1128 1316 3.3E-13 T 14-10-2018 A4R43_00625 1a13f2bbe9d2d3c39dfb3c59be7e5bd0 400 Pfam PF05977 Transmembrane secretion effector 5 387 7.5E-26 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_00625 1a13f2bbe9d2d3c39dfb3c59be7e5bd0 400 Gene3D G3DSA:1.20.1250.20 2 387 3.4E-35 T 14-10-2018 A4R43_00625 1a13f2bbe9d2d3c39dfb3c59be7e5bd0 400 SUPERFAMILY SSF103473 3 394 5.23E-41 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_22215 9ee507c4fb1323a5ef4f5648de92b283 189 Pfam PF08241 Methyltransferase domain 39 133 1.3E-17 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_22215 9ee507c4fb1323a5ef4f5648de92b283 189 Gene3D G3DSA:3.40.50.150 3 187 1.8E-27 T 14-10-2018 A4R43_22215 9ee507c4fb1323a5ef4f5648de92b283 189 SUPERFAMILY SSF53335 18 181 6.66E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_10325 45a43562d10d3a6acf383f7103de3cb1 427 SUPERFAMILY SSF103473 10 421 6.54E-61 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_10325 45a43562d10d3a6acf383f7103de3cb1 427 Pfam PF07690 Major Facilitator Superfamily 19 369 1.9E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_10325 45a43562d10d3a6acf383f7103de3cb1 427 Gene3D G3DSA:1.20.1250.20 10 425 1.1E-58 T 14-10-2018 A4R43_13485 d3f84408d8d3bbe47a8ae64c2b48fe5f 338 Pfam PF02720 Domain of unknown function (DUF222) 1 255 4.1E-10 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_28005 cb1dff6a15c6e550ebbd2255c7f269ba 62 SUPERFAMILY SSF50118 1 61 1.31E-21 T 14-10-2018 A4R43_28005 cb1dff6a15c6e550ebbd2255c7f269ba 62 Gene3D G3DSA:2.30.30.440 1 62 1.7E-25 T 14-10-2018 A4R43_28005 cb1dff6a15c6e550ebbd2255c7f269ba 62 Pfam PF08940 Domain of unknown function (DUF1918) 1 57 7.1E-27 T 14-10-2018 IPR015035 Domain of unknown function DUF1918 A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 Pfam PF00571 CBS domain 338 391 8.9E-6 T 14-10-2018 IPR000644 CBS domain A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 Pfam PF00571 CBS domain 406 454 4.3E-5 T 14-10-2018 IPR000644 CBS domain A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 Gene3D G3DSA:3.40.50.1100 9 304 2.9E-119 T 14-10-2018 A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 SUPERFAMILY SSF53686 2 317 2.75E-96 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 454 2.2E-200 T 14-10-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 2.7E-66 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 SMART SM00116 409 454 0.059 T 14-10-2018 IPR000644 CBS domain A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 SMART SM00116 339 392 7.9E-4 T 14-10-2018 IPR000644 CBS domain A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 Gene3D G3DSA:3.10.580.10 319 456 1.5E-17 T 14-10-2018 A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 SUPERFAMILY SSF54631 325 455 3.28E-16 T 14-10-2018 A4R43_23740 b33979bcb2a95022b1f64abf65170cb1 456 Gene3D G3DSA:3.40.50.1100 41 154 2.9E-119 T 14-10-2018 A4R43_18875 3693de4e25be6d67cebb96e374e8e6a9 403 Pfam PF02470 MlaD protein 39 114 6.0E-12 T 14-10-2018 IPR003399 Mce/MlaD A4R43_18875 3693de4e25be6d67cebb96e374e8e6a9 403 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 297 8.6E-57 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_06710 a6724647188ae30b57be7c9a17196016 434 SMART SM00387 234 346 6.1E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_06710 a6724647188ae30b57be7c9a17196016 434 SUPERFAMILY SSF55874 228 345 6.29E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_06710 a6724647188ae30b57be7c9a17196016 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 344 1.4E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_06710 a6724647188ae30b57be7c9a17196016 434 Gene3D G3DSA:3.30.565.10 203 344 2.5E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_02775 75fb14e193041551a27558960551fe86 294 SUPERFAMILY SSF53474 17 291 1.65E-59 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02775 75fb14e193041551a27558960551fe86 294 PRINTS PR00412 Epoxide hydrolase signature 235 251 7.1E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02775 75fb14e193041551a27558960551fe86 294 PRINTS PR00412 Epoxide hydrolase signature 47 65 7.1E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02775 75fb14e193041551a27558960551fe86 294 PRINTS PR00412 Epoxide hydrolase signature 111 124 7.1E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02775 75fb14e193041551a27558960551fe86 294 PRINTS PR00412 Epoxide hydrolase signature 268 290 7.1E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02775 75fb14e193041551a27558960551fe86 294 Gene3D G3DSA:3.40.50.1820 14 293 2.0E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02775 75fb14e193041551a27558960551fe86 294 Pfam PF00561 alpha/beta hydrolase fold 41 272 4.5E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02775 75fb14e193041551a27558960551fe86 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 7.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02775 75fb14e193041551a27558960551fe86 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 7.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02775 75fb14e193041551a27558960551fe86 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 81 7.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02575 170889f5fa11fc0ce855acfb21e2ceef 256 Pfam PF00498 FHA domain 28 99 2.5E-7 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4R43_02575 170889f5fa11fc0ce855acfb21e2ceef 256 SUPERFAMILY SSF49879 6 100 1.2E-12 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 A4R43_02575 170889f5fa11fc0ce855acfb21e2ceef 256 SUPERFAMILY SSF46894 143 250 7.09E-8 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_02575 170889f5fa11fc0ce855acfb21e2ceef 256 Gene3D G3DSA:2.60.200.20 1 105 1.4E-11 T 14-10-2018 A4R43_02575 170889f5fa11fc0ce855acfb21e2ceef 256 SMART SM00862 160 249 5.8E-5 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_02575 170889f5fa11fc0ce855acfb21e2ceef 256 Pfam PF00486 Transcriptional regulatory protein, C terminal 186 249 2.3E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_02575 170889f5fa11fc0ce855acfb21e2ceef 256 Gene3D G3DSA:1.10.10.10 131 251 1.7E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07140 83f9e4f7614014b294a4c75597584840 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 3.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 3.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 3.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 Gene3D G3DSA:3.40.50.12740 2 203 9.5E-67 T 14-10-2018 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 SMART SM00421 140 197 1.1E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 194 7.4E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 Pfam PF00072 Response regulator receiver domain 5 113 8.7E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 SMART SM00448 2 113 8.9E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 SUPERFAMILY SSF46894 133 203 1.09E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_07140 83f9e4f7614014b294a4c75597584840 209 SUPERFAMILY SSF52172 2 128 2.13E-32 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_13375 e3fe6eacaf65bc3f94648ae8644a8fb6 298 Pfam PF01522 Polysaccharide deacetylase 47 176 1.3E-19 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4R43_13375 e3fe6eacaf65bc3f94648ae8644a8fb6 298 Gene3D G3DSA:3.20.20.370 21 293 3.8E-79 T 14-10-2018 A4R43_13375 e3fe6eacaf65bc3f94648ae8644a8fb6 298 SUPERFAMILY SSF88713 23 291 4.23E-64 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4R43_12400 c29d274bab1d3f0690157ea52a6ecae0 946 SUPERFAMILY SSF48452 563 877 7.21E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12400 c29d274bab1d3f0690157ea52a6ecae0 946 Gene3D G3DSA:1.25.40.10 730 898 4.6E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12400 c29d274bab1d3f0690157ea52a6ecae0 946 Gene3D G3DSA:1.25.40.10 514 700 2.2E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12400 c29d274bab1d3f0690157ea52a6ecae0 946 Pfam PF13374 Tetratricopeptide repeat 757 793 0.0027 T 14-10-2018 A4R43_12400 c29d274bab1d3f0690157ea52a6ecae0 946 Pfam PF13374 Tetratricopeptide repeat 656 691 0.014 T 14-10-2018 A4R43_12400 c29d274bab1d3f0690157ea52a6ecae0 946 SUPERFAMILY SSF52540 103 249 1.2E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21280 affc9385754b97bdaef31990be821a38 975 SUPERFAMILY SSF48452 90 249 2.53E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21280 affc9385754b97bdaef31990be821a38 975 SUPERFAMILY SSF48452 672 867 1.17E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21280 affc9385754b97bdaef31990be821a38 975 PRINTS PR00364 Disease resistance protein signature 270 285 1.2E-7 T 14-10-2018 A4R43_21280 affc9385754b97bdaef31990be821a38 975 PRINTS PR00364 Disease resistance protein signature 425 439 1.2E-7 T 14-10-2018 A4R43_21280 affc9385754b97bdaef31990be821a38 975 PRINTS PR00364 Disease resistance protein signature 332 346 1.2E-7 T 14-10-2018 A4R43_21280 affc9385754b97bdaef31990be821a38 975 SMART SM01043 95 230 5.4E-42 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_21280 affc9385754b97bdaef31990be821a38 975 Gene3D G3DSA:1.10.10.10 1 91 4.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21280 affc9385754b97bdaef31990be821a38 975 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 88 1.8E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_21280 affc9385754b97bdaef31990be821a38 975 SUPERFAMILY SSF52540 241 491 3.02E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21280 affc9385754b97bdaef31990be821a38 975 Pfam PF03704 Bacterial transcriptional activator domain 106 230 1.0E-33 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_21280 affc9385754b97bdaef31990be821a38 975 Gene3D G3DSA:1.25.40.10 837 953 8.8E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21280 affc9385754b97bdaef31990be821a38 975 Gene3D G3DSA:1.25.40.10 660 836 2.4E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21280 affc9385754b97bdaef31990be821a38 975 SUPERFAMILY SSF48452 838 943 8.22E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21280 affc9385754b97bdaef31990be821a38 975 SUPERFAMILY SSF46894 2 88 1.9E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_21280 affc9385754b97bdaef31990be821a38 975 Gene3D G3DSA:1.25.40.10 93 249 8.0E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21280 affc9385754b97bdaef31990be821a38 975 Gene3D G3DSA:3.40.50.300 250 368 1.3E-6 T 14-10-2018 A4R43_21280 affc9385754b97bdaef31990be821a38 975 SMART SM00862 17 88 1.4E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_02930 f07adf344f9811a39bccd66d85fa9158 326 Gene3D G3DSA:1.10.10.10 86 166 3.0E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02930 f07adf344f9811a39bccd66d85fa9158 326 Pfam PF04542 Sigma-70 region 2 16 80 2.1E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_02930 f07adf344f9811a39bccd66d85fa9158 326 SUPERFAMILY SSF88946 15 93 5.89E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_02930 f07adf344f9811a39bccd66d85fa9158 326 SUPERFAMILY SSF88659 90 165 2.85E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_02930 f07adf344f9811a39bccd66d85fa9158 326 SMART SM00421 114 171 0.0016 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_02930 f07adf344f9811a39bccd66d85fa9158 326 Pfam PF08281 Sigma-70, region 4 114 159 4.1E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_02930 f07adf344f9811a39bccd66d85fa9158 326 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 162 3.6E-17 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_02930 f07adf344f9811a39bccd66d85fa9158 326 Gene3D G3DSA:1.10.1740.10 8 79 3.4E-9 T 14-10-2018 A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 SMART SM00342 220 304 7.6E-29 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 288 4.1E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 288 304 4.1E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 257 300 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 Gene3D G3DSA:1.10.10.60 199 308 3.5E-24 T 14-10-2018 A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 Pfam PF12852 Cupin 2 188 9.8E-47 T 14-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 Pfam PF12833 Helix-turn-helix domain 226 305 5.5E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 SUPERFAMILY SSF46689 203 253 2.15E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08250 1f615271232481a20bea4da4ab8b7148 309 SUPERFAMILY SSF46689 256 306 7.89E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_36920 f0760a8b10135b9fbde24c12b8a2b7ac 120 Gene3D G3DSA:1.10.10.10 2 106 7.5E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36920 f0760a8b10135b9fbde24c12b8a2b7ac 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 2.7E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_36920 f0760a8b10135b9fbde24c12b8a2b7ac 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 2.7E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_36920 f0760a8b10135b9fbde24c12b8a2b7ac 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 2.7E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_36920 f0760a8b10135b9fbde24c12b8a2b7ac 120 SMART SM00418 16 93 2.2E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_36920 f0760a8b10135b9fbde24c12b8a2b7ac 120 Pfam PF12840 Helix-turn-helix domain 16 72 1.4E-8 T 14-10-2018 A4R43_36920 f0760a8b10135b9fbde24c12b8a2b7ac 120 SUPERFAMILY SSF46785 3 93 6.92E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05910 46aab9a5700f0eba7fa68a80816fd0a9 485 Pfam PF00171 Aldehyde dehydrogenase family 23 474 1.3E-139 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_05910 46aab9a5700f0eba7fa68a80816fd0a9 485 Gene3D G3DSA:3.40.309.10 257 444 8.9E-141 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_05910 46aab9a5700f0eba7fa68a80816fd0a9 485 Gene3D G3DSA:3.40.605.10 25 473 8.9E-141 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_05910 46aab9a5700f0eba7fa68a80816fd0a9 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_05910 46aab9a5700f0eba7fa68a80816fd0a9 485 SUPERFAMILY SSF53720 14 477 4.45E-135 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 Gene3D G3DSA:3.30.160.40 217 313 9.0E-17 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 PIRSF PIRSF001438 1 313 2.1E-106 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 305 34.267 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 207 8.5E-69 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 Gene3D G3DSA:3.40.190.10 5 211 5.8E-75 T 14-10-2018 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 303 3.8E-89 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 223 303 4.7E-13 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 SUPERFAMILY SSF54782 216 310 2.35E-14 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 227 243 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 SUPERFAMILY SSF53850 3 212 2.05E-66 T 14-10-2018 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 PRINTS PR00151 Porphobilinogen deaminase signature 119 136 2.1E-23 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 PRINTS PR00151 Porphobilinogen deaminase signature 71 90 2.1E-23 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 PRINTS PR00151 Porphobilinogen deaminase signature 138 155 2.1E-23 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 PRINTS PR00151 Porphobilinogen deaminase signature 226 243 2.1E-23 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32925 55bbefbdbf5ff8784876cd6243bde9ab 313 Gene3D G3DSA:3.40.190.10 95 194 5.8E-75 T 14-10-2018 A4R43_10480 5f94da7bfd63722df3ef396604b8c71d 392 Gene3D G3DSA:1.20.1250.20 10 195 6.7E-11 T 14-10-2018 A4R43_10480 5f94da7bfd63722df3ef396604b8c71d 392 SUPERFAMILY SSF103473 2 386 1.11E-36 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_10480 5f94da7bfd63722df3ef396604b8c71d 392 Pfam PF07690 Major Facilitator Superfamily 13 334 3.7E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_10480 5f94da7bfd63722df3ef396604b8c71d 392 Gene3D G3DSA:1.20.1250.20 199 380 1.0E-25 T 14-10-2018 A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 Pfam PF00364 Biotin-requiring enzyme 3 73 5.2E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 SUPERFAMILY SSF52777 176 394 1.07E-68 T 14-10-2018 A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 Gene3D G3DSA:3.30.559.10 169 394 1.9E-73 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 SUPERFAMILY SSF47005 126 169 6.67E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 SUPERFAMILY SSF51230 3 92 1.96E-23 T 14-10-2018 IPR011053 Single hybrid motif A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 176 393 9.6E-68 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 Pfam PF02817 e3 binding domain 133 166 5.7E-13 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 Gene3D G3DSA:2.40.50.100 1 79 9.6E-22 T 14-10-2018 A4R43_41645 01cf1c4a72b4c45f078f654482cdf5bb 396 Gene3D G3DSA:4.10.320.10 127 168 3.1E-13 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 PRINTS PR00419 Adrenodoxin reductase family signature 178 191 1.0E-23 T 14-10-2018 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 1.0E-23 T 14-10-2018 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 PRINTS PR00419 Adrenodoxin reductase family signature 155 177 1.0E-23 T 14-10-2018 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 PRINTS PR00419 Adrenodoxin reductase family signature 220 230 1.0E-23 T 14-10-2018 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 SUPERFAMILY SSF51971 382 481 9.42E-11 T 14-10-2018 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 SUPERFAMILY SSF51971 153 416 2.0E-65 T 14-10-2018 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 32 140 9.2E-20 T 14-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 155 471 2.1E-28 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 Gene3D G3DSA:1.10.1060.10 7 153 3.0E-19 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 SUPERFAMILY SSF46548 5 164 2.62E-31 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 489 3.0E-188 T 14-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 Gene3D G3DSA:3.50.50.60 154 278 8.4E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17150 80b41c3fcff42efc2eb320e6f57afce7 502 Gene3D G3DSA:3.50.50.60 286 483 2.5E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18615 901960a3ecbc402374e3a4acecec1488 293 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 166 4.5E-48 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4R43_18615 901960a3ecbc402374e3a4acecec1488 293 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 172 280 1.6E-9 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_18615 901960a3ecbc402374e3a4acecec1488 293 Gene3D G3DSA:3.30.465.10 1 168 1.7E-52 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_18615 901960a3ecbc402374e3a4acecec1488 293 SUPERFAMILY SSF56176 2 165 7.55E-52 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_18615 901960a3ecbc402374e3a4acecec1488 293 SMART SM01092 171 281 6.3E-15 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_18615 901960a3ecbc402374e3a4acecec1488 293 SUPERFAMILY SSF55447 173 285 4.32E-18 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily A4R43_18615 901960a3ecbc402374e3a4acecec1488 293 Gene3D G3DSA:3.30.390.50 171 284 3.0E-20 T 14-10-2018 A4R43_08705 14b2659c3f1fd4ed5fb914de11486417 275 Gene3D G3DSA:3.40.50.1820 49 225 1.9E-8 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08705 14b2659c3f1fd4ed5fb914de11486417 275 SUPERFAMILY SSF53474 96 203 2.95E-10 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08705 14b2659c3f1fd4ed5fb914de11486417 275 Pfam PF06259 Alpha/beta hydrolase 41 218 1.6E-41 T 14-10-2018 IPR010427 Protein of unknown function DUF1023 A4R43_25255 9b74507365bfe6c4c80a4dcf6be57da7 313 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A4R43_25255 9b74507365bfe6c4c80a4dcf6be57da7 313 SUPERFAMILY SSF50129 1 150 1.57E-24 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_25255 9b74507365bfe6c4c80a4dcf6be57da7 313 Gene3D G3DSA:3.90.180.10 10 307 8.2E-73 T 14-10-2018 A4R43_25255 9b74507365bfe6c4c80a4dcf6be57da7 313 Gene3D G3DSA:3.40.50.720 125 257 8.2E-73 T 14-10-2018 A4R43_25255 9b74507365bfe6c4c80a4dcf6be57da7 313 Pfam PF13602 Zinc-binding dehydrogenase 184 310 5.5E-16 T 14-10-2018 A4R43_25255 9b74507365bfe6c4c80a4dcf6be57da7 313 SMART SM00829 10 311 1.3E-9 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_25255 9b74507365bfe6c4c80a4dcf6be57da7 313 SUPERFAMILY SSF51735 114 288 4.59E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40975 eae300dc3d8b809d671ebc5a37993d98 124 Gene3D G3DSA:1.10.10.10 4 121 8.3E-46 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40975 eae300dc3d8b809d671ebc5a37993d98 124 SUPERFAMILY SSF46785 7 120 1.99E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40975 eae300dc3d8b809d671ebc5a37993d98 124 Pfam PF01638 HxlR-like helix-turn-helix 22 109 4.8E-30 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_25190 d8a7d21ef0016a1db2d47920b1990938 199 Pfam PF13460 NAD(P)H-binding 8 188 3.6E-12 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_25190 d8a7d21ef0016a1db2d47920b1990938 199 Gene3D G3DSA:3.40.50.720 3 199 7.0E-30 T 14-10-2018 A4R43_25190 d8a7d21ef0016a1db2d47920b1990938 199 SUPERFAMILY SSF51735 2 198 5.97E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 Pfam PF09364 XFP N-terminal domain 9 362 3.7E-133 T 14-10-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 Gene3D G3DSA:3.40.50.920 585 767 4.5E-64 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 ProSitePatterns PS60002 Phosphoketolase signature 1. 135 141 - T 14-10-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 ProSitePatterns PS60003 Phosphoketolase signature 2. 148 166 - T 14-10-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 Gene3D G3DSA:3.40.50.970 366 584 2.6E-92 T 14-10-2018 A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 SUPERFAMILY SSF52518 9 347 2.44E-56 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 378 553 2.8E-76 T 14-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 SUPERFAMILY SSF52518 355 571 9.03E-23 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 PIRSF PIRSF017245 3 767 1.0E-292 T 14-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 Pfam PF09363 XFP C-terminal domain 565 766 1.4E-74 T 14-10-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 A4R43_15580 7ffb0cfdfe6233e3bf3fa36da05572f6 767 Gene3D G3DSA:3.40.50.970 4 363 4.2E-141 T 14-10-2018 A4R43_16530 d2fd02bf86aa378571cd49c6a296b389 421 SUPERFAMILY SSF51905 7 417 2.31E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_16530 d2fd02bf86aa378571cd49c6a296b389 421 Gene3D G3DSA:3.90.660.10 42 212 8.1E-22 T 14-10-2018 A4R43_16530 d2fd02bf86aa378571cd49c6a296b389 421 Gene3D G3DSA:1.10.405.10 109 201 8.1E-22 T 14-10-2018 A4R43_16530 d2fd02bf86aa378571cd49c6a296b389 421 Pfam PF01593 Flavin containing amine oxidoreductase 15 276 2.2E-17 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4R43_16530 d2fd02bf86aa378571cd49c6a296b389 421 Gene3D G3DSA:3.50.50.60 10 270 8.1E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23395 5c8104dc7378695bee8e939d27a191b5 332 SUPERFAMILY SSF52540 28 247 2.77E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23395 5c8104dc7378695bee8e939d27a191b5 332 Pfam PF00005 ABC transporter 42 186 3.5E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23395 5c8104dc7378695bee8e939d27a191b5 332 Gene3D G3DSA:3.40.50.300 27 285 1.9E-53 T 14-10-2018 A4R43_23395 5c8104dc7378695bee8e939d27a191b5 332 SMART SM00382 50 233 2.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_23395 5c8104dc7378695bee8e939d27a191b5 332 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_15495 af5475d0d315acc732c7876df63a4a72 377 Pfam PF01168 Alanine racemase, N-terminal domain 35 244 1.6E-24 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_15495 af5475d0d315acc732c7876df63a4a72 377 Gene3D G3DSA:3.20.20.10 36 242 2.3E-107 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_15495 af5475d0d315acc732c7876df63a4a72 377 Pfam PF14031 Putative serine dehydratase domain 260 364 8.5E-18 T 14-10-2018 IPR026956 D-serine dehydratase-like domain A4R43_15495 af5475d0d315acc732c7876df63a4a72 377 SUPERFAMILY SSF51419 35 243 1.19E-29 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_15495 af5475d0d315acc732c7876df63a4a72 377 SMART SM01119 260 367 4.2E-35 T 14-10-2018 IPR026956 D-serine dehydratase-like domain A4R43_15495 af5475d0d315acc732c7876df63a4a72 377 Gene3D G3DSA:2.40.37.20 29 366 2.3E-107 T 14-10-2018 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 SUPERFAMILY SSF56300 35 367 2.69E-62 T 14-10-2018 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 Gene3D G3DSA:3.60.21.10 36 368 3.7E-64 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 SUPERFAMILY SSF55816 367 566 1.02E-49 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 Pfam PF02872 5'-nucleotidase, C-terminal domain 370 529 1.1E-37 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 Gene3D G3DSA:3.90.780.10 376 566 5.6E-55 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 PRINTS PR01607 Apyrase family signature 433 456 1.6E-21 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 PRINTS PR01607 Apyrase family signature 303 323 1.6E-21 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 PRINTS PR01607 Apyrase family signature 504 523 1.6E-21 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 PRINTS PR01607 Apyrase family signature 39 57 1.6E-21 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 PRINTS PR01607 Apyrase family signature 272 295 1.6E-21 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4R43_31250 c968fb2df018fa736e27570681c3bd51 567 Pfam PF00149 Calcineurin-like phosphoesterase 43 289 3.9E-7 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 Gene3D G3DSA:1.10.10.60 208 321 1.9E-25 T 14-10-2018 A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 SUPERFAMILY SSF46689 265 314 1.57E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 SMART SM00342 229 312 6.1E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 Gene3D G3DSA:2.60.120.10 43 97 3.5E-5 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 SUPERFAMILY SSF46689 212 263 1.25E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 Pfam PF12852 Cupin 11 197 1.1E-48 T 14-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 SUPERFAMILY SSF51215 24 164 1.7E-7 T 14-10-2018 IPR037923 Transcription regulator HTH-like A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 312 1.5E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 296 1.5E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_08815 73c9f7986c68ff5e4ce1613b46614315 326 Pfam PF12833 Helix-turn-helix domain 235 314 2.9E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 Gene3D G3DSA:3.40.50.720 1 255 1.7E-76 T 14-10-2018 A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 4.7E-60 T 14-10-2018 A4R43_15340 48a8787a231956fa04e10a7a69b48b16 262 SUPERFAMILY SSF51735 10 251 1.59E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 Pfam PF00203 Ribosomal protein S19 3 83 2.1E-36 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 PIRSF PIRSF002144 1 93 4.1E-30 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.6E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.6E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.6E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.024 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 Gene3D G3DSA:3.30.860.10 1 93 1.3E-39 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 1.5E-47 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4R43_33860 a7ff01950cb4f7218f12e6fde7d71e19 93 SUPERFAMILY SSF54570 3 83 7.46E-35 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 Gene3D G3DSA:4.10.320.10 160 197 1.1E-6 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 SUPERFAMILY SSF52777 206 442 2.49E-81 T 14-10-2018 A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 Pfam PF00364 Biotin-requiring enzyme 6 78 9.8E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 Gene3D G3DSA:3.30.559.10 200 441 6.2E-83 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 SUPERFAMILY SSF51230 4 97 8.9E-24 T 14-10-2018 IPR011053 Single hybrid motif A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 Pfam PF02817 e3 binding domain 160 193 2.8E-7 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 Gene3D G3DSA:2.40.50.100 1 103 2.7E-23 T 14-10-2018 A4R43_31140 be74cd7aecc20c613ecabe11d115b9fc 445 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 215 443 1.7E-81 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 SUPERFAMILY SSF47384 147 230 3.34E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 SMART SM00387 274 396 4.8E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 Pfam PF00672 HAMP domain 111 159 1.8E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 SMART SM00304 110 163 5.5E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 SUPERFAMILY SSF158472 112 160 1.07E-7 T 14-10-2018 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 165 229 1.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 Gene3D G3DSA:1.10.287.130 114 230 3.1E-28 T 14-10-2018 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 SUPERFAMILY SSF55874 221 398 6.81E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 374 2.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 393 2.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 325 2.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 394 6.1E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 Gene3D G3DSA:3.30.565.10 233 402 3.8E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_02615 76fe20d551123ca95202de2f843d9a9a 427 SMART SM00388 164 231 1.1E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_29665 9821628c929625f8d8569e9d52e2fe39 297 Pfam PF00482 Type II secretion system (T2SS), protein F 161 288 1.8E-6 T 14-10-2018 IPR018076 Type II secretion system F domain A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 PIRSF PIRSF000381 1 1160 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 SUPERFAMILY SSF47644 637 718 7.06E-23 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 SUPERFAMILY SSF82282 7 381 2.49E-102 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 957 1159 3.6E-41 T 14-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Gene3D G3DSA:3.40.50.280 721 856 4.8E-41 T 14-10-2018 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Gene3D G3DSA:1.10.1240.10 630 716 9.8E-29 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Gene3D G3DSA:1.10.288.10 911 969 3.8E-56 T 14-10-2018 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Pfam PF02574 Homocysteine S-methyltransferase 17 306 4.4E-61 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Gene3D G3DSA:3.10.196.10 895 1159 3.8E-56 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 SUPERFAMILY SSF56507 886 1159 2.22E-93 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 SUPERFAMILY SSF51717 339 610 7.72E-73 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Gene3D G3DSA:3.20.20.330 2 318 8.1E-91 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 TIGRFAM TIGR02082 metH: methionine synthase 13 1157 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Pfam PF02607 B12 binding domain 640 712 1.1E-23 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Gene3D G3DSA:3.20.20.20 328 623 1.2E-94 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 SMART SM01018 637 719 4.9E-39 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Pfam PF02310 B12 binding domain 725 843 1.9E-20 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 SUPERFAMILY SSF52242 719 854 3.4E-37 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_40915 8f537faca6393631e95fcd0fed838f5f 1162 Pfam PF00809 Pterin binding enzyme 342 578 2.0E-43 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_22555 7d5f9fe3b714f251ba6cae574cf791ca 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 300 9.5E-44 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_01720 447caef9bd67cbc5f97eead445d09d88 126 SUPERFAMILY SSF142906 11 117 5.36E-34 T 14-10-2018 IPR038056 YjbR-like superfamily A4R43_01720 447caef9bd67cbc5f97eead445d09d88 126 Gene3D G3DSA:3.90.1150.30 3 123 3.3E-35 T 14-10-2018 IPR038056 YjbR-like superfamily A4R43_01720 447caef9bd67cbc5f97eead445d09d88 126 Pfam PF04237 YjbR 16 106 1.3E-25 T 14-10-2018 IPR007351 Uncharacterised protein YjbR A4R43_25885 05a5675fa3957bc2118f616a06aab15c 306 SUPERFAMILY SSF51197 39 306 2.01E-90 T 14-10-2018 A4R43_25885 05a5675fa3957bc2118f616a06aab15c 306 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 42 296 1.2E-62 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 A4R43_25885 05a5675fa3957bc2118f616a06aab15c 306 Gene3D G3DSA:3.60.130.10 39 306 4.5E-88 T 14-10-2018 A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 7 282 7.4E-98 T 14-10-2018 IPR014303 RNA polymerase sigma-70, ECF type A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 SUPERFAMILY SSF54427 168 287 7.83E-19 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 Pfam PF04542 Sigma-70 region 2 10 70 8.7E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 SUPERFAMILY SSF88946 9 88 1.22E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 Gene3D G3DSA:1.10.10.10 86 154 4.6E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 155 3.9E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 Gene3D G3DSA:3.10.450.50 155 285 6.4E-10 T 14-10-2018 A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 Pfam PF08281 Sigma-70, region 4 107 154 1.5E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 SUPERFAMILY SSF88659 88 159 2.43E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_11725 a77047863c6893fc183d5593f3e4959e 296 Gene3D G3DSA:1.10.1740.10 5 74 4.5E-11 T 14-10-2018 A4R43_02400 01c17632c383b45b7538efee016bf749 344 SUPERFAMILY SSF51735 148 288 2.1E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_02400 01c17632c383b45b7538efee016bf749 344 Gene3D G3DSA:3.90.180.10 8 323 1.7E-86 T 14-10-2018 A4R43_02400 01c17632c383b45b7538efee016bf749 344 Gene3D G3DSA:3.40.50.720 157 286 1.7E-86 T 14-10-2018 A4R43_02400 01c17632c383b45b7538efee016bf749 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 3.1E-17 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_02400 01c17632c383b45b7538efee016bf749 344 SUPERFAMILY SSF50129 1 179 2.89E-40 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_02400 01c17632c383b45b7538efee016bf749 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_02400 01c17632c383b45b7538efee016bf749 344 Pfam PF00107 Zinc-binding dehydrogenase 180 295 1.3E-17 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Gene3D G3DSA:3.30.200.20 6 100 8.1E-32 T 14-10-2018 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Pfam PF03793 PASTA domain 550 611 1.8E-11 T 14-10-2018 IPR005543 PASTA domain A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Pfam PF03793 PASTA domain 479 543 1.5E-4 T 14-10-2018 IPR005543 PASTA domain A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Pfam PF03793 PASTA domain 614 674 6.0E-11 T 14-10-2018 IPR005543 PASTA domain A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Pfam PF03793 PASTA domain 413 473 3.8E-11 T 14-10-2018 IPR005543 PASTA domain A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Gene3D G3DSA:1.10.510.10 102 290 6.3E-47 T 14-10-2018 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Gene3D G3DSA:3.30.10.20 612 675 3.6E-12 T 14-10-2018 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Pfam PF00069 Protein kinase domain 17 273 2.8E-42 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 SMART SM00740 614 677 1.7E-7 T 14-10-2018 IPR005543 PASTA domain A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 SMART SM00740 544 612 6.3E-9 T 14-10-2018 IPR005543 PASTA domain A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 SMART SM00740 408 474 3.6E-7 T 14-10-2018 IPR005543 PASTA domain A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 SMART SM00740 475 543 5.5 T 14-10-2018 IPR005543 PASTA domain A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 SUPERFAMILY SSF56112 15 368 4.67E-74 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 SMART SM00220 17 283 9.1E-60 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Gene3D G3DSA:3.30.10.20 476 544 2.8E-6 T 14-10-2018 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Gene3D G3DSA:3.30.10.20 408 475 6.6E-15 T 14-10-2018 A4R43_17090 686db8508b5973e647fc9f7e919a4ffa 677 Gene3D G3DSA:3.30.10.20 545 611 5.3E-14 T 14-10-2018 A4R43_08825 ed68255328131c688f2954a11a6f3822 162 Pfam PF08592 Domain of unknown function (DUF1772) 22 157 2.9E-18 T 14-10-2018 A4R43_26340 28317d51098fa6314dee1c279bf25b92 107 SUPERFAMILY SSF46785 2 96 6.68E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26340 28317d51098fa6314dee1c279bf25b92 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 8.7E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_26340 28317d51098fa6314dee1c279bf25b92 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 8.7E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_26340 28317d51098fa6314dee1c279bf25b92 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 8.7E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_26340 28317d51098fa6314dee1c279bf25b92 107 SMART SM00418 3 81 2.6E-27 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_26340 28317d51098fa6314dee1c279bf25b92 107 Pfam PF12840 Helix-turn-helix domain 3 58 6.1E-17 T 14-10-2018 A4R43_26340 28317d51098fa6314dee1c279bf25b92 107 Gene3D G3DSA:1.10.10.10 1 103 1.9E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 SUPERFAMILY SSF55021 3 71 2.16E-7 T 14-10-2018 A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 Gene3D G3DSA:1.10.150.210 195 255 5.0E-71 T 14-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 185 355 1.6E-30 T 14-10-2018 A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 Gene3D G3DSA:3.30.70.260 95 181 1.3E-25 T 14-10-2018 A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 Pfam PF13740 ACT domain 6 77 5.9E-18 T 14-10-2018 A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 173 387 4.4E-75 T 14-10-2018 A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 Pfam PF12710 haloacid dehalogenase-like hydrolase 186 353 1.1E-25 T 14-10-2018 A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 Gene3D G3DSA:3.30.70.260 2 82 2.7E-12 T 14-10-2018 A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 Gene3D G3DSA:3.40.50.1000 184 375 5.0E-71 T 14-10-2018 IPR023214 HAD superfamily A4R43_36255 39772a69c7c6e70bef4187059032d13f 409 SUPERFAMILY SSF56784 183 392 5.6E-50 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_12795 152543731b5dfdfc7d4c2945beda021c 230 SUPERFAMILY SSF49899 29 228 2.49E-45 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_12795 152543731b5dfdfc7d4c2945beda021c 230 Gene3D G3DSA:2.60.120.180 31 230 8.6E-53 T 14-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_12795 152543731b5dfdfc7d4c2945beda021c 230 Pfam PF01670 Glycosyl hydrolase family 12 77 226 1.1E-17 T 14-10-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 A4R43_21715 22a18f5adf72a93616210ec908bdccc8 336 Gene3D G3DSA:1.10.1020.10 51 167 8.9E-16 T 14-10-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 A4R43_21715 22a18f5adf72a93616210ec908bdccc8 336 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 16 126 4.4E-5 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A4R43_21715 22a18f5adf72a93616210ec908bdccc8 336 SUPERFAMILY SSF53335 15 266 3.49E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_21715 22a18f5adf72a93616210ec908bdccc8 336 Gene3D G3DSA:3.40.50.150 15 266 8.9E-16 T 14-10-2018 A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 Pfam PF13193 AMP-binding enzyme C-terminal domain 410 485 2.7E-14 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 Gene3D G3DSA:1.10.1200.10 501 582 2.1E-28 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 SUPERFAMILY SSF47336 505 578 7.46E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 32 426 4.3E-125 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 Pfam PF00550 Phosphopantetheine attachment site 515 578 1.1E-16 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 ProSitePatterns PS00012 Phosphopantetheine attachment site. 537 552 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 SUPERFAMILY SSF56801 6 526 1.44E-152 T 14-10-2018 A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 Gene3D G3DSA:3.40.50.12780 2 396 1.1E-135 T 14-10-2018 A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 Gene3D G3DSA:3.30.300.30 397 500 1.2E-34 T 14-10-2018 A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 Pfam PF00501 AMP-binding enzyme 11 402 3.7E-93 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08310 5c40d06105a7edb6bbce457f46a076c2 582 SMART SM00823 Phosphopantetheine attachment site 513 582 3.4E-6 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_19315 961a4048d939c538680855ac54175c63 547 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 428 446 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A4R43_19315 961a4048d939c538680855ac54175c63 547 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 521 6.8E-79 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A4R43_19315 961a4048d939c538680855ac54175c63 547 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 122 1.5E-20 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A4R43_19315 961a4048d939c538680855ac54175c63 547 Gene3D G3DSA:3.50.30.10 7 228 9.7E-56 T 14-10-2018 A4R43_19315 961a4048d939c538680855ac54175c63 547 SUPERFAMILY SSF52009 121 240 1.44E-30 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A4R43_19315 961a4048d939c538680855ac54175c63 547 SUPERFAMILY SSF47831 30 139 2.62E-18 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 A4R43_19315 961a4048d939c538680855ac54175c63 547 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 220 2.6E-23 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4R43_19315 961a4048d939c538680855ac54175c63 547 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 428 443 6.4E-21 T 14-10-2018 A4R43_19315 961a4048d939c538680855ac54175c63 547 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 284 303 6.4E-21 T 14-10-2018 A4R43_19315 961a4048d939c538680855ac54175c63 547 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 445 460 6.4E-21 T 14-10-2018 A4R43_19315 961a4048d939c538680855ac54175c63 547 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 481 493 6.4E-21 T 14-10-2018 A4R43_19315 961a4048d939c538680855ac54175c63 547 PIRSF PIRSF000732 1 547 1.6E-157 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A4R43_19315 961a4048d939c538680855ac54175c63 547 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 7 536 3.3E-116 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A4R43_19315 961a4048d939c538680855ac54175c63 547 Gene3D G3DSA:3.20.20.60 229 547 2.6E-99 T 14-10-2018 A4R43_19315 961a4048d939c538680855ac54175c63 547 SUPERFAMILY SSF51621 242 522 3.93E-87 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_19315 961a4048d939c538680855ac54175c63 547 Gene3D G3DSA:1.10.274.10 24 142 9.7E-56 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 A4R43_19315 961a4048d939c538680855ac54175c63 547 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 180 191 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A4R43_09635 04697de110f93262795154227ab931a6 925 Gene3D G3DSA:1.10.10.1100 431 505 1.8E-78 T 14-10-2018 A4R43_09635 04697de110f93262795154227ab931a6 925 Gene3D G3DSA:3.50.50.60 119 512 1.8E-78 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09635 04697de110f93262795154227ab931a6 925 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 246 2.3E-9 T 14-10-2018 A4R43_09635 04697de110f93262795154227ab931a6 925 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 367 2.3E-9 T 14-10-2018 A4R43_09635 04697de110f93262795154227ab931a6 925 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 139 2.3E-9 T 14-10-2018 A4R43_09635 04697de110f93262795154227ab931a6 925 SUPERFAMILY SSF51905 108 400 1.55E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09635 04697de110f93262795154227ab931a6 925 Gene3D G3DSA:3.30.1360.120 530 916 1.1E-98 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4R43_09635 04697de110f93262795154227ab931a6 925 SUPERFAMILY SSF103025 531 819 7.22E-97 T 14-10-2018 A4R43_09635 04697de110f93262795154227ab931a6 925 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 809 908 1.4E-12 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4R43_09635 04697de110f93262795154227ab931a6 925 SUPERFAMILY SSF101790 829 924 9.16E-13 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A4R43_09635 04697de110f93262795154227ab931a6 925 Gene3D G3DSA:3.50.50.60 240 359 1.8E-78 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09635 04697de110f93262795154227ab931a6 925 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 168 8.1E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_09635 04697de110f93262795154227ab931a6 925 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 237 8.1E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_09635 04697de110f93262795154227ab931a6 925 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 292 8.1E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_09635 04697de110f93262795154227ab931a6 925 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 141 8.1E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_09635 04697de110f93262795154227ab931a6 925 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 14 97 1.1E-20 T 14-10-2018 A4R43_09635 04697de110f93262795154227ab931a6 925 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 119 367 7.4E-13 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_09635 04697de110f93262795154227ab931a6 925 Pfam PF01571 Aminomethyltransferase folate-binding domain 537 803 1.4E-74 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 Gene3D G3DSA:3.30.300.30 413 510 9.5E-22 T 14-10-2018 A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 Gene3D G3DSA:1.10.1200.10 512 603 7.9E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 788 816 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 Pfam PF00501 AMP-binding enzyme 49 417 7.9E-66 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 Gene3D G3DSA:2.160.10.10 1201 1306 2.3E-11 T 14-10-2018 A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 780 812 7.3E-5 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 SUPERFAMILY SSF51161 1191 1301 2.36E-18 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 Pfam PF00550 Phosphopantetheine attachment site 531 593 1.3E-8 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 SUPERFAMILY SSF51161 723 831 9.56E-19 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 615 1301 3.6E-232 T 14-10-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 67 441 3.1E-98 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 SUPERFAMILY SSF47336 525 594 8.64E-13 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 SMART SM00823 Phosphopantetheine attachment site 529 597 6.4E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 Gene3D G3DSA:2.160.10.10 712 835 9.7E-15 T 14-10-2018 A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 Gene3D G3DSA:3.40.50.12780 35 412 2.2E-94 T 14-10-2018 A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 SUPERFAMILY SSF51161 870 1066 3.6E-10 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_14130 2c39ef40c19ad5359fcd179266515e22 1312 SUPERFAMILY SSF56801 38 542 8.63E-111 T 14-10-2018 A4R43_03995 c75eae268611b0a85ed5ca18f0eb0b48 121 Pfam PF14248 Domain of unknown function (DUF4345) 3 120 7.0E-21 T 14-10-2018 IPR025597 Protein of unknown function DUF4345 A4R43_39475 a7c559c4e59dceba60b98dfd33fc100c 139 Gene3D G3DSA:3.10.450.30 47 138 2.8E-34 T 14-10-2018 A4R43_39475 a7c559c4e59dceba60b98dfd33fc100c 139 SUPERFAMILY SSF53933 47 137 1.9E-31 T 14-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 A4R43_39475 a7c559c4e59dceba60b98dfd33fc100c 139 Pfam PF00545 ribonuclease 54 133 5.3E-27 T 14-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 A4R43_04605 7e00ebbc6321027b0abff4fc115f4bad 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 3.0E-25 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_04605 7e00ebbc6321027b0abff4fc115f4bad 88 PRINTS PR00107 Phosphocarrier protein signature 39 54 3.6E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_04605 7e00ebbc6321027b0abff4fc115f4bad 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.6E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_04605 7e00ebbc6321027b0abff4fc115f4bad 88 PRINTS PR00107 Phosphocarrier protein signature 54 71 3.6E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_04605 7e00ebbc6321027b0abff4fc115f4bad 88 Pfam PF00381 PTS HPr component phosphorylation site 3 83 4.3E-24 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_04605 7e00ebbc6321027b0abff4fc115f4bad 88 Gene3D G3DSA:3.30.1340.10 1 87 5.0E-25 T 14-10-2018 IPR035895 HPr-like superfamily A4R43_04605 7e00ebbc6321027b0abff4fc115f4bad 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A4R43_04605 7e00ebbc6321027b0abff4fc115f4bad 88 SUPERFAMILY SSF55594 1 87 3.79E-22 T 14-10-2018 IPR035895 HPr-like superfamily A4R43_14040 189a9c2b7a8e67900a372046e6d65633 235 Gene3D G3DSA:3.40.50.1820 4 213 2.5E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14040 189a9c2b7a8e67900a372046e6d65633 235 SUPERFAMILY SSF53474 5 208 8.04E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13345 17269ec8108bb46478433a50df7f1caf 311 PIRSF PIRSF000103 1 292 3.8E-66 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_13345 17269ec8108bb46478433a50df7f1caf 311 Gene3D G3DSA:1.10.1040.10 162 290 8.9E-26 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_13345 17269ec8108bb46478433a50df7f1caf 311 SUPERFAMILY SSF48179 165 288 3.74E-24 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_13345 17269ec8108bb46478433a50df7f1caf 311 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 283 7.8E-15 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A4R43_13345 17269ec8108bb46478433a50df7f1caf 311 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 160 1.1E-35 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_13345 17269ec8108bb46478433a50df7f1caf 311 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_13345 17269ec8108bb46478433a50df7f1caf 311 SUPERFAMILY SSF51735 1 162 2.84E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13345 17269ec8108bb46478433a50df7f1caf 311 Gene3D G3DSA:3.40.50.720 1 161 5.3E-44 T 14-10-2018 A4R43_16425 a642783ab0212f127120a6c9ab582386 360 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 18 342 2.0E-87 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_16425 a642783ab0212f127120a6c9ab582386 360 Pfam PF04542 Sigma-70 region 2 27 93 5.9E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_16425 a642783ab0212f127120a6c9ab582386 360 Gene3D G3DSA:3.10.450.50 213 340 1.1E-8 T 14-10-2018 A4R43_16425 a642783ab0212f127120a6c9ab582386 360 SUPERFAMILY SSF88946 3 101 4.12E-26 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_16425 a642783ab0212f127120a6c9ab582386 360 SUPERFAMILY SSF54427 216 329 2.51E-10 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_16425 a642783ab0212f127120a6c9ab582386 360 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 201 2.4E-21 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_16425 a642783ab0212f127120a6c9ab582386 360 SUPERFAMILY SSF88659 134 205 1.08E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_16425 a642783ab0212f127120a6c9ab582386 360 Pfam PF08281 Sigma-70, region 4 148 199 1.6E-9 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_16425 a642783ab0212f127120a6c9ab582386 360 Gene3D G3DSA:1.10.1740.10 2 107 2.5E-26 T 14-10-2018 A4R43_16425 a642783ab0212f127120a6c9ab582386 360 Pfam PF12680 SnoaL-like domain 223 319 1.5E-6 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_16425 a642783ab0212f127120a6c9ab582386 360 Gene3D G3DSA:1.10.10.10 126 204 1.9E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37340 f70e4c6ef0e3b784e440caab5715a288 151 Gene3D G3DSA:1.10.10.10 3 132 1.9E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37340 f70e4c6ef0e3b784e440caab5715a288 151 SUPERFAMILY SSF46785 7 129 1.42E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_37340 f70e4c6ef0e3b784e440caab5715a288 151 SMART SM00347 20 119 1.7E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_37340 f70e4c6ef0e3b784e440caab5715a288 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 95 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_37340 f70e4c6ef0e3b784e440caab5715a288 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 129 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_37340 f70e4c6ef0e3b784e440caab5715a288 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 75 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_37340 f70e4c6ef0e3b784e440caab5715a288 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 43 59 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_37340 f70e4c6ef0e3b784e440caab5715a288 151 Pfam PF12802 MarR family 25 83 5.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_33040 3abe28a3763a120a387b66cbfdc9d633 250 SUPERFAMILY SSF88713 2 247 1.63E-94 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4R43_33040 3abe28a3763a120a387b66cbfdc9d633 250 Gene3D G3DSA:3.20.20.370 1 249 1.8E-101 T 14-10-2018 A4R43_33040 3abe28a3763a120a387b66cbfdc9d633 250 Pfam PF03746 LamB/YcsF family 3 240 4.0E-101 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A4R43_33040 3abe28a3763a120a387b66cbfdc9d633 250 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 244 44.215 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A4R43_22015 3fbcef40a6c2e929d29da81364eaccb2 323 Gene3D G3DSA:1.10.10.10 1 64 2.6E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22015 3fbcef40a6c2e929d29da81364eaccb2 323 PIRSF PIRSF016838 1 56 0.0028 T 14-10-2018 IPR028349 Protein PafC A4R43_22015 3fbcef40a6c2e929d29da81364eaccb2 323 PIRSF PIRSF016838 67 321 2.3E-14 T 14-10-2018 IPR028349 Protein PafC A4R43_22015 3fbcef40a6c2e929d29da81364eaccb2 323 Pfam PF13280 WYL domain 139 314 2.5E-42 T 14-10-2018 IPR026881 WYL domain A4R43_22015 3fbcef40a6c2e929d29da81364eaccb2 323 Pfam PF08279 HTH domain 10 60 1.1E-13 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_22015 3fbcef40a6c2e929d29da81364eaccb2 323 SUPERFAMILY SSF46785 3 63 2.45E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_12220 878ffa3808506bb508953abb13030ac8 553 PRINTS PR00819 CbxX/CfqX superfamily signature 286 300 1.8E-53 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 PRINTS PR00819 CbxX/CfqX superfamily signature 448 467 1.8E-53 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 PRINTS PR00819 CbxX/CfqX superfamily signature 505 517 1.8E-53 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 PRINTS PR00819 CbxX/CfqX superfamily signature 326 341 1.8E-53 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 PRINTS PR00819 CbxX/CfqX superfamily signature 364 378 1.8E-53 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 PRINTS PR00819 CbxX/CfqX superfamily signature 378 397 1.8E-53 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 PRINTS PR00819 CbxX/CfqX superfamily signature 410 422 1.8E-53 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 PRINTS PR00819 CbxX/CfqX superfamily signature 431 448 1.8E-53 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 Gene3D G3DSA:1.10.8.60 461 548 2.4E-17 T 14-10-2018 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 328 460 6.1E-18 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SMART SM00710 215 237 4700.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SMART SM00710 238 260 7100.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SMART SM00710 146 168 210.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SMART SM00710 192 214 520.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SMART SM00710 102 124 80.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SMART SM00710 169 191 9.2 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_12220 878ffa3808506bb508953abb13030ac8 553 Gene3D G3DSA:3.40.50.300 276 460 6.7E-55 T 14-10-2018 A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SUPERFAMILY SSF52540 288 523 8.74E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12220 878ffa3808506bb508953abb13030ac8 553 Pfam PF13229 Right handed beta helix region 76 216 1.4E-13 T 14-10-2018 IPR039448 Right handed beta helix domain A4R43_12220 878ffa3808506bb508953abb13030ac8 553 Gene3D G3DSA:2.160.20.10 25 269 1.6E-20 T 14-10-2018 IPR012334 Pectin lyase fold A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SMART SM00382 323 463 2.6E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12220 878ffa3808506bb508953abb13030ac8 553 SUPERFAMILY SSF51126 8 252 4.44E-32 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_04825 1c28c62be52e20cd7d3ec954509751da 168 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 18 155 9.0E-51 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04825 1c28c62be52e20cd7d3ec954509751da 168 SUPERFAMILY SSF52121 15 160 2.49E-51 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04825 1c28c62be52e20cd7d3ec954509751da 168 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 14 158 26.298 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04825 1c28c62be52e20cd7d3ec954509751da 168 Gene3D G3DSA:3.40.50.960 8 161 1.4E-54 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04825 1c28c62be52e20cd7d3ec954509751da 168 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 19 154 1.5E-40 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 PIRSF PIRSF000137 1 541 2.0E-128 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 SUPERFAMILY SSF54373 298 483 3.92E-44 T 14-10-2018 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 Gene3D G3DSA:3.30.410.40 160 480 1.4E-157 T 14-10-2018 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 Gene3D G3DSA:3.50.50.60 11 537 1.4E-157 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 Gene3D G3DSA:4.10.450.10 43 206 1.4E-157 T 14-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 91 114 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 Gene3D G3DSA:1.10.1220.110 106 159 1.4E-157 T 14-10-2018 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 Pfam PF00732 GMC oxidoreductase 12 303 4.3E-73 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 Pfam PF05199 GMC oxidoreductase 398 531 9.8E-37 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_07675 052079c7c687ce8a9e767fd517b046fe 541 SUPERFAMILY SSF51905 9 539 7.25E-76 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 Pfam PF13191 AAA ATPase domain 10 149 2.2E-12 T 14-10-2018 A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 SUPERFAMILY SSF46894 839 894 1.05E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 ProSitePatterns PS00622 LuxR-type HTH domain signature. 858 885 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 858 874 1.6E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 874 886 1.6E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 844 858 1.6E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 Gene3D G3DSA:1.10.10.10 834 896 2.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 Gene3D G3DSA:1.25.40.10 506 833 1.3E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 Pfam PF00196 Bacterial regulatory proteins, luxR family 843 894 2.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 SUPERFAMILY SSF52540 9 220 1.07E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37625 6b0b6000b881edb02d97be36942b8621 909 SMART SM00421 841 898 7.1E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Pfam PF00679 Elongation factor G C-terminus 408 493 3.8E-21 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 SUPERFAMILY SSF50447 174 296 1.11E-23 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 285.268 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Pfam PF00009 Elongation factor Tu GTP binding domain 14 190 3.3E-52 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Pfam PF06421 GTP-binding protein LepA C-terminus 498 602 1.4E-48 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 SMART SM00838 410 491 4.2E-4 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Gene3D G3DSA:3.40.50.300 12 194 1.8E-70 T 14-10-2018 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 16 183 1.9E-19 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 SUPERFAMILY SSF54980 408 503 1.44E-22 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 SUPERFAMILY SSF52540 8 212 3.03E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Gene3D G3DSA:3.30.70.2570 489 563 4.2E-33 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Gene3D G3DSA:3.30.70.870 295 376 7.4E-34 T 14-10-2018 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Gene3D G3DSA:3.30.70.3380 377 487 2.0E-40 T 14-10-2018 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 SUPERFAMILY SSF54980 300 379 8.63E-19 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 TIGRFAM TIGR01393 lepA: elongation factor 4 13 604 3.0E-294 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 PRINTS PR00315 GTP-binding elongation factor signature 16 29 3.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39430 4acd52f17244eb35db399fa9d91b30ae 616 Gene3D G3DSA:2.40.30.10 195 294 3.9E-32 T 14-10-2018 A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 5.8E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 5.8E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 5.8E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 Gene3D G3DSA:3.40.50.720 1 250 5.9E-69 T 14-10-2018 A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 SUPERFAMILY SSF51735 5 249 2.58E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 8.0E-45 T 14-10-2018 A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.1E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.1E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.1E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.1E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 3.1E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_18290 404a9fc56d647a83726f2db73f252fcd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.1E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34620 df30ebc20976b79d7a42b42b95d12583 211 Gene3D G3DSA:1.10.3210.10 14 209 1.9E-56 T 14-10-2018 A4R43_34620 df30ebc20976b79d7a42b42b95d12583 211 Pfam PF13023 HD domain 29 191 4.1E-48 T 14-10-2018 IPR006674 HD domain A4R43_34620 df30ebc20976b79d7a42b42b95d12583 211 SUPERFAMILY SSF109604 21 199 6.99E-39 T 14-10-2018 A4R43_09565 e0c1413add74ed210ee57eb68f45fe37 463 Gene3D G3DSA:3.40.640.10 73 348 9.6E-154 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_09565 e0c1413add74ed210ee57eb68f45fe37 463 SUPERFAMILY SSF53383 20 457 2.77E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_09565 e0c1413add74ed210ee57eb68f45fe37 463 Pfam PF00202 Aminotransferase class-III 40 456 6.7E-94 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_09565 e0c1413add74ed210ee57eb68f45fe37 463 PIRSF PIRSF000521 41 459 1.2E-24 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_09565 e0c1413add74ed210ee57eb68f45fe37 463 Gene3D G3DSA:3.90.1150.10 20 456 9.6E-154 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_09565 e0c1413add74ed210ee57eb68f45fe37 463 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 SUPERFAMILY SSF54416 4 77 2.33E-17 T 14-10-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 Pfam PF02728 Copper amine oxidase, N3 domain 89 185 7.2E-16 T 14-10-2018 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 Gene3D G3DSA:3.10.450.40 92 193 1.8E-24 T 14-10-2018 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 Pfam PF01179 Copper amine oxidase, enzyme domain 211 607 1.5E-152 T 14-10-2018 IPR015798 Copper amine oxidase, catalytic domain GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 Pfam PF02727 Copper amine oxidase, N2 domain 4 44 7.5E-5 T 14-10-2018 IPR015800 Copper amine oxidase, N2-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 Gene3D G3DSA:2.70.98.20 194 607 2.3E-165 T 14-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 SUPERFAMILY SSF54416 89 197 3.92E-26 T 14-10-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 ProSitePatterns PS01164 Copper amine oxidase topaquinone signature. 356 369 - T 14-10-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 Gene3D G3DSA:3.10.450.40 1 84 1.3E-9 T 14-10-2018 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 SUPERFAMILY SSF49998 199 607 4.32E-153 T 14-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_15500 9d1d8e6415be64d1fcd1ba0a91fd4054 607 ProSitePatterns PS01165 Copper amine oxidase copper-binding site signature. 568 581 - T 14-10-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_09675 2b5ab5f91bf9ffe419c0d49d37f7f141 115 Gene3D G3DSA:2.102.10.10 1 105 1.8E-34 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_09675 2b5ab5f91bf9ffe419c0d49d37f7f141 115 SUPERFAMILY SSF50022 3 97 3.93E-28 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_09675 2b5ab5f91bf9ffe419c0d49d37f7f141 115 Pfam PF00355 Rieske [2Fe-2S] domain 3 84 7.4E-18 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4R43_34280 1e9011f35921d3e8413e75b44ea12a3a 625 SUPERFAMILY SSF53955 28 78 4.42E-5 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_34280 1e9011f35921d3e8413e75b44ea12a3a 625 SUPERFAMILY SSF55846 247 400 2.88E-37 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_34280 1e9011f35921d3e8413e75b44ea12a3a 625 Gene3D G3DSA:3.40.80.10 245 401 9.2E-40 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_34280 1e9011f35921d3e8413e75b44ea12a3a 625 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 257 385 2.4E-26 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_34280 1e9011f35921d3e8413e75b44ea12a3a 625 SMART SM00644 248 384 1.7E-39 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_34280 1e9011f35921d3e8413e75b44ea12a3a 625 SUPERFAMILY SSF53955 134 171 4.82E-5 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_08850 a5c38a209c06b1a1190853331ffc09e8 333 Gene3D G3DSA:1.10.10.10 8 68 3.5E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08850 a5c38a209c06b1a1190853331ffc09e8 333 ProSitePatterns PS00894 DeoR-type HTH domain signature. 10 44 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_08850 a5c38a209c06b1a1190853331ffc09e8 333 Pfam PF13280 WYL domain 145 315 7.2E-28 T 14-10-2018 IPR026881 WYL domain A4R43_08850 a5c38a209c06b1a1190853331ffc09e8 333 Pfam PF08279 HTH domain 10 65 2.0E-14 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_08850 a5c38a209c06b1a1190853331ffc09e8 333 SUPERFAMILY SSF46785 8 66 2.53E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08850 a5c38a209c06b1a1190853331ffc09e8 333 PIRSF PIRSF016838 1 319 6.1E-24 T 14-10-2018 IPR028349 Protein PafC A4R43_20005 f04f2f6ba7fa1e7b1f6f56558d5f8d15 140 Pfam PF10756 Bacterial PH domain 61 130 1.1E-14 T 14-10-2018 IPR019692 Protein of unknown function DUF2581 A4R43_20005 f04f2f6ba7fa1e7b1f6f56558d5f8d15 140 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 57 131 2.0E-10 T 14-10-2018 IPR020535 Low molecular weight antigen Cfp6 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 SUPERFAMILY SSF51905 2 370 2.08E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 Pfam PF01494 FAD binding domain 2 335 8.6E-71 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 Gene3D G3DSA:3.40.30.120 385 486 9.9E-13 T 14-10-2018 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 286 2.9E-41 T 14-10-2018 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 2.9E-41 T 14-10-2018 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 302 2.9E-41 T 14-10-2018 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 322 2.9E-41 T 14-10-2018 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.9E-41 T 14-10-2018 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 338 2.9E-41 T 14-10-2018 A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 Gene3D G3DSA:3.50.50.60 3 335 1.5E-104 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00785 84e368091b47ec45e07568d6232ba6a1 490 Gene3D G3DSA:3.30.70.2450 175 260 1.5E-104 T 14-10-2018 A4R43_35185 2356fa5c99e3bc7e0842590f329b184c 215 SUPERFAMILY SSF46689 12 82 9.23E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35185 2356fa5c99e3bc7e0842590f329b184c 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 3.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35185 2356fa5c99e3bc7e0842590f329b184c 215 Gene3D G3DSA:1.10.357.10 13 201 2.0E-23 T 14-10-2018 A4R43_35185 2356fa5c99e3bc7e0842590f329b184c 215 SUPERFAMILY SSF48498 88 199 1.39E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_34525 87bf56380b030c9ce923479c65948e2a 516 Gene3D G3DSA:2.30.40.20 35 73 5.3E-18 T 14-10-2018 A4R43_34525 87bf56380b030c9ce923479c65948e2a 516 SUPERFAMILY SSF56672 9 231 1.51E-37 T 14-10-2018 A4R43_34525 87bf56380b030c9ce923479c65948e2a 516 Gene3D G3DSA:1.10.150.20 170 225 5.3E-18 T 14-10-2018 A4R43_34525 87bf56380b030c9ce923479c65948e2a 516 Pfam PF00817 impB/mucB/samB family 29 153 1.2E-16 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_34525 87bf56380b030c9ce923479c65948e2a 516 Gene3D G3DSA:3.30.70.270 74 230 5.3E-18 T 14-10-2018 A4R43_24050 ce9b2d84573a3bb8ca1b732a85d4e524 115 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 6.9E-12 T 14-10-2018 IPR019933 DivIVA domain A4R43_24050 ce9b2d84573a3bb8ca1b732a85d4e524 115 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 45 81 6.3E-12 T 14-10-2018 IPR019933 DivIVA domain A4R43_21065 ec7b14fd4ddd0c1e5c47dba12e923dd0 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 4.1E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21065 ec7b14fd4ddd0c1e5c47dba12e923dd0 223 Gene3D G3DSA:3.40.50.12740 1 205 3.1E-33 T 14-10-2018 A4R43_21065 ec7b14fd4ddd0c1e5c47dba12e923dd0 223 SMART SM00421 147 204 9.2E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21065 ec7b14fd4ddd0c1e5c47dba12e923dd0 223 SUPERFAMILY SSF52172 9 131 4.5E-7 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_21065 ec7b14fd4ddd0c1e5c47dba12e923dd0 223 SUPERFAMILY SSF46894 138 203 7.82E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_21065 ec7b14fd4ddd0c1e5c47dba12e923dd0 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21065 ec7b14fd4ddd0c1e5c47dba12e923dd0 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21065 ec7b14fd4ddd0c1e5c47dba12e923dd0 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32550 e5f068f9dda0e1ca1feb865d1b1a93d6 224 SUPERFAMILY SSF46689 8 80 6.31E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_32550 e5f068f9dda0e1ca1feb865d1b1a93d6 224 Gene3D G3DSA:1.10.357.10 2 223 2.1E-69 T 14-10-2018 A4R43_32550 e5f068f9dda0e1ca1feb865d1b1a93d6 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 1.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32550 e5f068f9dda0e1ca1feb865d1b1a93d6 224 SUPERFAMILY SSF48498 89 217 7.78E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 Pfam PF00561 alpha/beta hydrolase fold 22 263 1.8E-25 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 PRINTS PR00412 Epoxide hydrolase signature 105 118 3.7E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 PRINTS PR00412 Epoxide hydrolase signature 28 46 3.7E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 PRINTS PR00412 Epoxide hydrolase signature 91 104 3.7E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 PRINTS PR00412 Epoxide hydrolase signature 253 275 3.7E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 2.2E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 2.2E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 2.2E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 Gene3D G3DSA:3.40.50.1820 1 277 1.2E-95 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01365 9d06b4eccf1cf734d7c24291294ac6db 277 SUPERFAMILY SSF53474 2 277 8.18E-82 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02490 5d279d77cb6e805cfaa97bf043fd2822 163 Pfam PF00293 NUDIX domain 11 72 3.7E-12 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_02490 5d279d77cb6e805cfaa97bf043fd2822 163 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_02490 5d279d77cb6e805cfaa97bf043fd2822 163 Gene3D G3DSA:3.90.79.10 3 145 1.2E-19 T 14-10-2018 A4R43_02490 5d279d77cb6e805cfaa97bf043fd2822 163 SUPERFAMILY SSF55811 12 144 1.27E-21 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_02490 5d279d77cb6e805cfaa97bf043fd2822 163 PRINTS PR00502 NUDIX hydrolase family signature 36 50 7.8E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_02490 5d279d77cb6e805cfaa97bf043fd2822 163 PRINTS PR00502 NUDIX hydrolase family signature 50 65 7.8E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_12455 ca2f75708f158429428da3cfb19b1bae 401 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 238 366 1.3E-14 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4R43_12455 ca2f75708f158429428da3cfb19b1bae 401 Gene3D G3DSA:2.40.110.10 124 212 2.9E-24 T 14-10-2018 A4R43_12455 ca2f75708f158429428da3cfb19b1bae 401 PIRSF PIRSF016578 2 386 3.0E-66 T 14-10-2018 A4R43_12455 ca2f75708f158429428da3cfb19b1bae 401 SUPERFAMILY SSF56645 7 211 1.69E-24 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_12455 ca2f75708f158429428da3cfb19b1bae 401 Gene3D G3DSA:1.10.540.10 9 116 8.9E-16 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_12455 ca2f75708f158429428da3cfb19b1bae 401 Gene3D G3DSA:1.20.140.10 213 386 2.6E-21 T 14-10-2018 A4R43_12455 ca2f75708f158429428da3cfb19b1bae 401 SUPERFAMILY SSF47203 224 377 2.09E-8 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 Pfam PF00553 Cellulose binding domain 44 144 4.8E-32 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 Gene3D G3DSA:2.60.40.10 153 246 3.0E-29 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 Pfam PF02011 Glycosyl hydrolase family 48 346 978 0.0 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 Gene3D G3DSA:1.50.10.10 346 978 5.8E-300 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 Gene3D G3DSA:2.60.40.290 37 146 8.6E-34 T 14-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 Gene3D G3DSA:2.170.160.10 433 663 5.8E-300 T 14-10-2018 IPR023309 Endoglucanase F, domain 2 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 SMART SM00637 44 144 4.9E-45 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 Gene3D G3DSA:4.10.870.10 890 961 5.8E-300 T 14-10-2018 IPR027390 Endoglucanase F, domain 3 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 558 585 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 631 650 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 398 415 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 701 724 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 372 397 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 747 773 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 911 939 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 513 537 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 PRINTS PR00844 Glycosyl hydrolase family 48 signature 802 822 1.4E-100 T 14-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 109 122 - T 14-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 SUPERFAMILY SSF49384 43 145 3.91E-30 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A4R43_06420 a546e4cca90a1eabd8763b76d27abaa9 981 SUPERFAMILY SSF48208 343 979 3.64E-278 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_24970 606d5adc1f5931fcf9b7674bce80f32e 142 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 89 98 6.4E-7 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4R43_24970 606d5adc1f5931fcf9b7674bce80f32e 142 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 79 87 6.4E-7 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4R43_24970 606d5adc1f5931fcf9b7674bce80f32e 142 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 6.4E-7 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4R43_24970 606d5adc1f5931fcf9b7674bce80f32e 142 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 2 126 8.9E-37 T 14-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L A4R43_24970 606d5adc1f5931fcf9b7674bce80f32e 142 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 2 129 3.5E-28 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4R43_24970 606d5adc1f5931fcf9b7674bce80f32e 142 SUPERFAMILY SSF81330 10 123 8.76E-27 T 14-10-2018 IPR036019 Gated mechanosensitive channel A4R43_24970 606d5adc1f5931fcf9b7674bce80f32e 142 Gene3D G3DSA:1.10.1200.120 1 130 8.2E-39 T 14-10-2018 IPR036019 Gated mechanosensitive channel A4R43_24970 606d5adc1f5931fcf9b7674bce80f32e 142 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 128 20.162 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4R43_02820 a8ac3b319ab4f0968982caeb0980394c 66 SUPERFAMILY SSF46785 7 44 6.82E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02820 a8ac3b319ab4f0968982caeb0980394c 66 Pfam PF09339 IclR helix-turn-helix domain 10 39 2.6E-6 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_02820 a8ac3b319ab4f0968982caeb0980394c 66 Gene3D G3DSA:1.10.10.10 5 45 2.1E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_33765 26a1cd06b0ebaa768587640d16ea43e2 394 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 127 5.1E-22 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_33765 26a1cd06b0ebaa768587640d16ea43e2 394 Gene3D G3DSA:3.30.360.10 143 381 2.9E-75 T 14-10-2018 A4R43_33765 26a1cd06b0ebaa768587640d16ea43e2 394 SUPERFAMILY SSF51735 6 170 3.94E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_33765 26a1cd06b0ebaa768587640d16ea43e2 394 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 150 259 1.9E-11 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A4R43_33765 26a1cd06b0ebaa768587640d16ea43e2 394 SUPERFAMILY SSF55347 144 302 1.59E-37 T 14-10-2018 A4R43_33765 26a1cd06b0ebaa768587640d16ea43e2 394 Gene3D G3DSA:3.40.50.720 4 142 5.5E-39 T 14-10-2018 A4R43_03665 059c38e3d154bd406819e6569f16f332 465 Gene3D G3DSA:1.20.1740.10 6 446 4.0E-49 T 14-10-2018 A4R43_03665 059c38e3d154bd406819e6569f16f332 465 Pfam PF13520 Amino acid permease 12 410 2.7E-33 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_03665 059c38e3d154bd406819e6569f16f332 465 PIRSF PIRSF006060 3 443 8.2E-51 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_32070 5c88ca8e340ead186b0b8f2f3478d61f 144 PIRSF PIRSF030042 17 142 2.5E-9 T 14-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 A4R43_32070 5c88ca8e340ead186b0b8f2f3478d61f 144 PIRSF PIRSF030042 3 54 1.3 T 14-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 A4R43_32070 5c88ca8e340ead186b0b8f2f3478d61f 144 Pfam PF14340 Domain of unknown function (DUF4395) 7 136 1.2E-45 T 14-10-2018 IPR025508 Domain of unknown function DUF4395 A4R43_27255 644a93a6b2b13a99aa50edd90bc88a0c 313 Gene3D G3DSA:3.60.21.10 43 252 1.3E-15 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_27255 644a93a6b2b13a99aa50edd90bc88a0c 313 Pfam PF00149 Calcineurin-like phosphoesterase 44 228 1.8E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_27255 644a93a6b2b13a99aa50edd90bc88a0c 313 SUPERFAMILY SSF56300 38 284 3.8E-26 T 14-10-2018 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Pfam PF13424 Tetratricopeptide repeat 830 901 2.0E-9 T 14-10-2018 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SUPERFAMILY SSF48452 90 253 2.09E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Gene3D G3DSA:1.25.40.10 691 808 4.8E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SUPERFAMILY SSF52540 264 519 2.67E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Gene3D G3DSA:3.40.50.300 260 413 4.2E-30 T 14-10-2018 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SUPERFAMILY SSF48452 729 904 8.06E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SMART SM00862 16 88 9.0E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Gene3D G3DSA:1.25.40.10 93 259 2.2E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 75 2.0E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Gene3D G3DSA:1.10.10.10 1 91 3.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Pfam PF00931 NB-ARC domain 276 474 1.6E-12 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SUPERFAMILY SSF48452 872 982 2.34E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 PRINTS PR00364 Disease resistance protein signature 294 309 5.2E-10 T 14-10-2018 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 PRINTS PR00364 Disease resistance protein signature 371 385 5.2E-10 T 14-10-2018 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 PRINTS PR00364 Disease resistance protein signature 456 470 5.2E-10 T 14-10-2018 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SMART SM00028 830 863 4.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SMART SM00028 870 903 1.9 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SMART SM00028 950 983 27.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SMART SM00028 750 783 21.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SMART SM01043 95 239 5.6E-34 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Pfam PF03704 Bacterial transcriptional activator domain 95 239 2.7E-33 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 Gene3D G3DSA:1.25.40.10 809 983 2.0E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_39675 fadbc2ec487bff249451714040ff758c 1004 SUPERFAMILY SSF46894 22 88 4.25E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 ProSitePatterns PS01244 Aconitase family signature 2. 531 544 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 ProSitePatterns PS00450 Aconitase family signature 1. 465 481 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 Pfam PF00694 Aconitase C-terminal domain 729 859 3.7E-44 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 SUPERFAMILY SSF52016 669 933 1.0E-82 T 14-10-2018 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 SUPERFAMILY SSF53732 8 665 6.28E-225 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 Gene3D G3DSA:3.20.19.10 692 935 1.2E-102 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 Gene3D G3DSA:1.10.1440.20 629 690 4.6E-22 T 14-10-2018 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 Gene3D G3DSA:3.30.499.20 11 367 4.0E-156 T 14-10-2018 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 367 381 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 531 544 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 145 158 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 169 177 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 198 211 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 212 227 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 288 301 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 469 480 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 PRINTS PR00415 Aconitase family signature 274 287 2.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_11120 0068e6a6bb1dca3f999ad9caaa0cbc00 935 Pfam PF00330 Aconitase family (aconitate hydratase) 68 600 1.3E-178 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_07965 a242fc58f65fac342454767e7033e24b 506 Gene3D G3DSA:2.115.10.20 190 506 5.1E-142 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_07965 a242fc58f65fac342454767e7033e24b 506 SUPERFAMILY SSF75005 217 498 8.37E-24 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_07965 a242fc58f65fac342454767e7033e24b 506 SUPERFAMILY SSF50370 40 181 2.37E-48 T 14-10-2018 IPR035992 Ricin B-like lectins A4R43_07965 a242fc58f65fac342454767e7033e24b 506 SMART SM00458 44 180 2.2E-14 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_07965 a242fc58f65fac342454767e7033e24b 506 Gene3D G3DSA:2.80.10.50 88 134 8.3E-16 T 14-10-2018 A4R43_07965 a242fc58f65fac342454767e7033e24b 506 Gene3D G3DSA:2.80.10.50 135 186 7.4E-13 T 14-10-2018 A4R43_07965 a242fc58f65fac342454767e7033e24b 506 Gene3D G3DSA:2.80.10.50 37 87 1.3E-12 T 14-10-2018 A4R43_07965 a242fc58f65fac342454767e7033e24b 506 Pfam PF03664 Glycosyl hydrolase family 62 189 472 1.6E-79 T 14-10-2018 IPR005193 Glycoside hydrolase, family 62, arabinosidase GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 A4R43_07965 a242fc58f65fac342454767e7033e24b 506 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 126 183 8.9E-13 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_07965 a242fc58f65fac342454767e7033e24b 506 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 43 120 2.6E-22 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 SMART SM00448 2 115 2.0E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 SUPERFAMILY SSF46894 141 213 7.82E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 8.8E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 8.8E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 8.8E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 Pfam PF00072 Response regulator receiver domain 4 114 1.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 SUPERFAMILY SSF52172 1 131 6.12E-33 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 205 1.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 SMART SM00421 151 208 5.8E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_40985 9e34dfd90cf66a547b4670831aa4af8f 214 Gene3D G3DSA:3.40.50.12740 2 214 9.7E-63 T 14-10-2018 A4R43_16850 ee9cd0fafce92f3bc09ea921a10b6163 307 SUPERFAMILY SSF52540 9 152 2.01E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16850 ee9cd0fafce92f3bc09ea921a10b6163 307 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 285 8.9E-73 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4R43_16850 ee9cd0fafce92f3bc09ea921a10b6163 307 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 297 27.21 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4R43_16850 ee9cd0fafce92f3bc09ea921a10b6163 307 Gene3D G3DSA:1.10.20.140 115 185 2.8E-90 T 14-10-2018 A4R43_16850 ee9cd0fafce92f3bc09ea921a10b6163 307 Gene3D G3DSA:3.40.50.300 12 284 2.8E-90 T 14-10-2018 A4R43_16850 ee9cd0fafce92f3bc09ea921a10b6163 307 Pfam PF01715 IPP transferase 41 281 1.0E-72 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4R43_31570 28cc0b738a6f98d0f4f4abd05556c5b4 201 Gene3D G3DSA:1.10.10.10 112 198 1.4E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31570 28cc0b738a6f98d0f4f4abd05556c5b4 201 SUPERFAMILY SSF88659 126 194 2.83E-5 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_31570 28cc0b738a6f98d0f4f4abd05556c5b4 201 SUPERFAMILY SSF88946 23 124 8.16E-18 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31570 28cc0b738a6f98d0f4f4abd05556c5b4 201 Gene3D G3DSA:1.10.1740.10 19 105 1.5E-15 T 14-10-2018 A4R43_31570 28cc0b738a6f98d0f4f4abd05556c5b4 201 Pfam PF04542 Sigma-70 region 2 40 100 1.4E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31570 28cc0b738a6f98d0f4f4abd05556c5b4 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 192 1.7E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_25790 ecf93497fee93e27080062d12c668595 480 Pfam PF00860 Permease family 22 434 4.3E-27 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A4R43_29980 939b744ced21db0de2523f70704381c1 532 SUPERFAMILY SSF52096 25 270 1.16E-63 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_29980 939b744ced21db0de2523f70704381c1 532 SUPERFAMILY SSF52096 232 513 2.28E-70 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_29980 939b744ced21db0de2523f70704381c1 532 Gene3D G3DSA:3.90.226.10 1 267 2.3E-77 T 14-10-2018 A4R43_29980 939b744ced21db0de2523f70704381c1 532 Pfam PF01039 Carboxyl transferase domain 48 521 4.8E-120 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_29980 939b744ced21db0de2523f70704381c1 532 Gene3D G3DSA:3.90.226.10 269 532 1.8E-83 T 14-10-2018 A4R43_18385 77cee5648aa59b318c7111ff6b0547ab 248 PIRSF PIRSF005650 5 245 2.1E-85 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A4R43_18385 77cee5648aa59b318c7111ff6b0547ab 248 Pfam PF00696 Amino acid kinase family 12 219 2.2E-30 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A4R43_18385 77cee5648aa59b318c7111ff6b0547ab 248 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 10 240 4.7E-88 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A4R43_18385 77cee5648aa59b318c7111ff6b0547ab 248 SUPERFAMILY SSF53633 10 239 9.16E-70 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4R43_18385 77cee5648aa59b318c7111ff6b0547ab 248 Hamap MF_01220_B Uridylate kinase [pyrH]. 8 240 42.349 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A4R43_18385 77cee5648aa59b318c7111ff6b0547ab 248 Gene3D G3DSA:3.40.1160.10 4 243 8.7E-76 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4R43_16260 c9f251e394126cd3f7635e291570a072 536 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 273 280 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_16260 c9f251e394126cd3f7635e291570a072 536 Gene3D G3DSA:3.40.309.10 277 470 7.0E-150 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_16260 c9f251e394126cd3f7635e291570a072 536 SUPERFAMILY SSF53720 41 505 3.4E-137 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_16260 c9f251e394126cd3f7635e291570a072 536 Pfam PF00171 Aldehyde dehydrogenase family 47 501 1.3E-141 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_16260 c9f251e394126cd3f7635e291570a072 536 Gene3D G3DSA:3.40.605.10 48 498 7.0E-150 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_23755 96ddb6323a988f2470566fd32856554c 272 PIRSF PIRSF009160 1 272 9.0E-85 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 A4R43_23755 96ddb6323a988f2470566fd32856554c 272 Pfam PF12811 Bax inhibitor 1 like 41 271 2.7E-87 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 A4R43_21870 7aaf9c34e56e7bde4abf94474174cf93 399 SUPERFAMILY SSF55031 209 317 1.92E-19 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_21870 7aaf9c34e56e7bde4abf94474174cf93 399 PIRSF PIRSF001235 5 399 9.1E-105 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A4R43_21870 7aaf9c34e56e7bde4abf94474174cf93 399 Gene3D G3DSA:3.40.630.10 18 392 4.9E-107 T 14-10-2018 A4R43_21870 7aaf9c34e56e7bde4abf94474174cf93 399 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 8 395 6.3E-75 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A4R43_21870 7aaf9c34e56e7bde4abf94474174cf93 399 Gene3D G3DSA:3.30.70.360 207 320 4.9E-107 T 14-10-2018 A4R43_21870 7aaf9c34e56e7bde4abf94474174cf93 399 SUPERFAMILY SSF53187 16 397 6.29E-61 T 14-10-2018 A4R43_21870 7aaf9c34e56e7bde4abf94474174cf93 399 Pfam PF01546 Peptidase family M20/M25/M40 71 395 6.6E-22 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_26020 004360bc4bd838cd79bfb9c68a04afff 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 1.9E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_26020 004360bc4bd838cd79bfb9c68a04afff 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_26020 004360bc4bd838cd79bfb9c68a04afff 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_26020 004360bc4bd838cd79bfb9c68a04afff 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_26020 004360bc4bd838cd79bfb9c68a04afff 212 Gene3D G3DSA:1.10.357.10 3 207 3.2E-38 T 14-10-2018 A4R43_26020 004360bc4bd838cd79bfb9c68a04afff 212 SUPERFAMILY SSF46689 8 86 8.21E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_07160 fd2ebf168d33a62439325ea3044c22bd 146 Gene3D G3DSA:3.10.129.10 4 140 3.7E-34 T 14-10-2018 A4R43_07160 fd2ebf168d33a62439325ea3044c22bd 146 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 137 3.7E-17 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A4R43_07160 fd2ebf168d33a62439325ea3044c22bd 146 Pfam PF03061 Thioesterase superfamily 51 125 4.9E-8 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_07160 fd2ebf168d33a62439325ea3044c22bd 146 SUPERFAMILY SSF54637 6 141 3.84E-28 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_32000 3794ab0f0d23f601f46992f23e5fe11c 280 Gene3D G3DSA:1.10.1760.20 76 260 4.8E-7 T 14-10-2018 A4R43_32000 3794ab0f0d23f601f46992f23e5fe11c 280 Pfam PF12822 ECF transporter, substrate-specific component 78 250 8.6E-17 T 14-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 A4R43_32000 3794ab0f0d23f601f46992f23e5fe11c 280 PIRSF PIRSF037395 7 275 2.0E-89 T 14-10-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 A4R43_28255 7edfeaaff1f901e50eb6f133be591162 320 Gene3D G3DSA:3.30.360.10 123 275 1.1E-47 T 14-10-2018 A4R43_28255 7edfeaaff1f901e50eb6f133be591162 320 SUPERFAMILY SSF51735 4 156 1.81E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28255 7edfeaaff1f901e50eb6f133be591162 320 Gene3D G3DSA:3.40.50.720 4 292 1.1E-47 T 14-10-2018 A4R43_28255 7edfeaaff1f901e50eb6f133be591162 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 115 6.8E-18 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_28255 7edfeaaff1f901e50eb6f133be591162 320 SUPERFAMILY SSF55347 123 222 2.4E-8 T 14-10-2018 A4R43_00115 11a91f121399d2f11c2a34b977a3c4db 162 Pfam PF00583 Acetyltransferase (GNAT) family 38 151 1.3E-14 T 14-10-2018 IPR000182 GNAT domain A4R43_00115 11a91f121399d2f11c2a34b977a3c4db 162 SUPERFAMILY SSF55729 2 154 1.72E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_00115 11a91f121399d2f11c2a34b977a3c4db 162 Gene3D G3DSA:3.40.630.30 19 156 1.5E-22 T 14-10-2018 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 Gene3D G3DSA:3.40.50.300 2 192 6.8E-6 T 14-10-2018 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 Gene3D G3DSA:1.10.10.10 894 964 1.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 SUPERFAMILY SSF52540 10 259 3.73E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 Pfam PF13191 AAA ATPase domain 10 179 1.6E-29 T 14-10-2018 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 Pfam PF00196 Bacterial regulatory proteins, luxR family 903 956 1.5E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 SMART SM00421 900 957 4.4E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 933 945 1.0E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 903 917 1.0E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 917 933 1.0E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 SUPERFAMILY SSF46894 900 963 2.52E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 SUPERFAMILY SSF48452 500 680 2.46E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_41205 afa62b11230af5d9d1ddb1a6e33f1440 964 Gene3D G3DSA:1.25.40.10 488 771 8.8E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21010 5304f86f252cd09652b07bd895bf9b35 251 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 244 3.8E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_21010 5304f86f252cd09652b07bd895bf9b35 251 SUPERFAMILY SSF161098 53 236 4.84E-34 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_21010 5304f86f252cd09652b07bd895bf9b35 251 Gene3D G3DSA:1.10.3720.10 53 244 1.8E-26 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 PIRSF PIRSF000460 1 801 3.0E-250 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 713 7.7E-226 T 14-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 SUPERFAMILY SSF53756 4 740 1.85E-191 T 14-10-2018 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 Pfam PF11897 Protein of unknown function (DUF3417) 13 123 7.4E-33 T 14-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 Gene3D G3DSA:3.40.50.2000 252 428 5.2E-11 T 14-10-2018 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 Gene3D G3DSA:3.40.50.2000 120 188 1.7E-11 T 14-10-2018 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 Pfam PF00343 Carbohydrate phosphorylase 273 625 1.1E-16 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 Pfam PF00343 Carbohydrate phosphorylase 128 173 5.0E-7 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 Gene3D G3DSA:3.40.50.2000 444 639 1.3E-35 T 14-10-2018 A4R43_20460 6e9d91218836d132bc863b51326c2d0f 852 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 603 615 - T 14-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A4R43_19495 dfebc222f0053f9f607f4af767e38ff3 529 SUPERFAMILY SSF101473 5 198 1.44E-33 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_19495 dfebc222f0053f9f607f4af767e38ff3 529 Pfam PF13684 Dihydroxyacetone kinase family 222 529 1.9E-58 T 14-10-2018 IPR033470 Uncharacterised protein, DhaK domain A4R43_19495 dfebc222f0053f9f607f4af767e38ff3 529 Gene3D G3DSA:1.25.40.340 6 199 8.8E-7 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_19495 dfebc222f0053f9f607f4af767e38ff3 529 SMART SM01120 34 196 8.7E-44 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_19495 dfebc222f0053f9f607f4af767e38ff3 529 Pfam PF02734 DAK2 domain 34 195 1.6E-32 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_19495 dfebc222f0053f9f607f4af767e38ff3 529 SMART SM01121 221 529 3.8E-51 T 14-10-2018 IPR033470 Uncharacterised protein, DhaK domain A4R43_31450 52fac78b639b8558a690e92165818f3e 134 Pfam PF10861 Protein of Unknown function (DUF2784) 4 110 1.4E-29 T 14-10-2018 IPR021218 Protein of unknown function DUF2784 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 209 217 - T 14-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 Gene3D G3DSA:3.30.470.30 184 375 2.2E-51 T 14-10-2018 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 68 497 1.8E-78 T 14-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 Hamap MF_00407 DNA ligase [lig]. 1 502 26.092 T 14-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 SUPERFAMILY SSF56091 181 375 4.6E-44 T 14-10-2018 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 Pfam PF04679 ATP dependent DNA ligase C terminal region 394 486 2.6E-11 T 14-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 SUPERFAMILY SSF117018 8 200 1.44E-31 T 14-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 Pfam PF01068 ATP dependent DNA ligase domain 187 375 7.9E-41 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 SUPERFAMILY SSF50249 377 497 2.4E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 Gene3D G3DSA:2.40.50.140 376 504 1.9E-30 T 14-10-2018 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 Gene3D G3DSA:1.10.3260.10 1 183 5.1E-43 T 14-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A4R43_23560 d27048f3e6845b9f95f9fcc8df33f693 508 Pfam PF04675 DNA ligase N terminus 69 139 1.5E-10 T 14-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A4R43_31745 06e5239195d6ff544582f15cabe07457 269 Pfam PF04672 S-adenosyl methyltransferase 8 268 1.6E-73 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_31745 06e5239195d6ff544582f15cabe07457 269 Gene3D G3DSA:3.40.50.150 2 269 4.3E-86 T 14-10-2018 A4R43_31745 06e5239195d6ff544582f15cabe07457 269 SUPERFAMILY SSF53335 16 255 1.63E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_31745 06e5239195d6ff544582f15cabe07457 269 PIRSF PIRSF017393 2 269 3.2E-78 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_26000 4ab9b4e99ce83af90a296ab86f21486e 390 Pfam PF07690 Major Facilitator Superfamily 21 350 7.6E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_26000 4ab9b4e99ce83af90a296ab86f21486e 390 SUPERFAMILY SSF103473 9 386 4.05E-54 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_26000 4ab9b4e99ce83af90a296ab86f21486e 390 Gene3D G3DSA:1.20.1250.20 10 387 4.2E-41 T 14-10-2018 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Gene3D G3DSA:2.40.110.10 453 563 5.2E-35 T 14-10-2018 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 SUPERFAMILY SSF47203 559 699 5.48E-12 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Gene3D G3DSA:1.10.540.10 3 113 1.0E-13 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 SUPERFAMILY SSF47203 211 342 1.93E-31 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 89 1.7E-5 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 363 449 4.3E-12 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 559 697 2.5E-11 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 213 331 1.8E-22 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Gene3D G3DSA:1.20.140.10 564 702 6.4E-19 T 14-10-2018 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 453 547 1.7E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 SUPERFAMILY SSF56645 373 572 6.68E-61 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Gene3D G3DSA:1.20.140.10 207 341 3.1E-32 T 14-10-2018 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 SUPERFAMILY SSF56645 4 198 4.19E-21 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16125 dbe9df7874806a01bedba03df9531a02 702 Gene3D G3DSA:1.10.540.10 342 450 6.7E-14 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_35520 30ae027ed7801d1fbe8386e27c8c8c4a 201 SUPERFAMILY SSF48498 86 196 2.45E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_35520 30ae027ed7801d1fbe8386e27c8c8c4a 201 Gene3D G3DSA:1.10.357.10 60 200 2.8E-18 T 14-10-2018 A4R43_35520 30ae027ed7801d1fbe8386e27c8c8c4a 201 Gene3D G3DSA:1.10.10.60 1 59 6.2E-16 T 14-10-2018 A4R43_35520 30ae027ed7801d1fbe8386e27c8c8c4a 201 SUPERFAMILY SSF46689 6 78 2.31E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35520 30ae027ed7801d1fbe8386e27c8c8c4a 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 7.2E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35520 30ae027ed7801d1fbe8386e27c8c8c4a 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.4E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35520 30ae027ed7801d1fbe8386e27c8c8c4a 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.4E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 Pfam PF00106 short chain dehydrogenase 14 205 1.5E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 SUPERFAMILY SSF51735 9 282 4.69E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 200 0.006 T 14-10-2018 A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.2E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.2E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.2E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.0E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.0E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.0E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.0E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.0E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 Gene3D G3DSA:3.40.50.720 3 284 2.4E-69 T 14-10-2018 A4R43_03855 b131445a54e7351a2b8db9b7c40cf171 289 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 SUPERFAMILY SSF52540 6 248 8.16E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 Gene3D G3DSA:1.25.40.10 607 853 2.9E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 Pfam PF13191 AAA ATPase domain 2 172 8.2E-20 T 14-10-2018 A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 SUPERFAMILY SSF46894 868 927 2.35E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 Gene3D G3DSA:1.10.10.10 854 931 5.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 890 906 5.1E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 906 918 5.1E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 876 890 5.1E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 Pfam PF00196 Bacterial regulatory proteins, luxR family 875 927 1.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05615 08531c730e32f4823e3bedfd0451c814 938 SMART SM00421 873 930 2.1E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28870 4413b2fc8d9881f6c812f2b05650970d 260 Gene3D G3DSA:1.10.3720.10 54 253 6.5E-28 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_28870 4413b2fc8d9881f6c812f2b05650970d 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 249 8.8E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_28870 4413b2fc8d9881f6c812f2b05650970d 260 SUPERFAMILY SSF161098 60 246 6.41E-30 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_26225 6d0b9616e54cd050e52e51d26e87ee72 266 Gene3D G3DSA:3.40.50.1110 6 191 1.2E-27 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_26225 6d0b9616e54cd050e52e51d26e87ee72 266 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 9 181 7.1E-27 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_26225 6d0b9616e54cd050e52e51d26e87ee72 266 SUPERFAMILY SSF52266 6 190 3.51E-34 T 14-10-2018 A4R43_13770 cea3e6c69555bf7861411166712179c4 453 Gene3D G3DSA:3.10.20.70 22 115 1.5E-6 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_13770 cea3e6c69555bf7861411166712179c4 453 SMART SM01230 119 368 2.4E-86 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_13770 cea3e6c69555bf7861411166712179c4 453 Pfam PF00120 Glutamine synthetase, catalytic domain 120 437 5.8E-82 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_13770 cea3e6c69555bf7861411166712179c4 453 SUPERFAMILY SSF54368 18 119 2.35E-8 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_13770 cea3e6c69555bf7861411166712179c4 453 SUPERFAMILY SSF55931 119 439 3.83E-87 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_13770 cea3e6c69555bf7861411166712179c4 453 Gene3D G3DSA:3.30.590.10 116 451 3.2E-104 T 14-10-2018 A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 Gene3D G3DSA:3.30.410.40 152 466 2.5E-188 T 14-10-2018 A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 SUPERFAMILY SSF51905 5 526 1.17E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 SUPERFAMILY SSF54373 291 469 9.61E-42 T 14-10-2018 A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 Gene3D G3DSA:1.10.1220.110 97 151 2.5E-188 T 14-10-2018 A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 PIRSF PIRSF000137 1 530 1.4E-154 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 Gene3D G3DSA:3.50.50.60 7 523 2.5E-188 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 Gene3D G3DSA:4.10.450.10 40 197 2.5E-188 T 14-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 Pfam PF00732 GMC oxidoreductase 7 297 4.9E-91 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_31835 a5b1454066fe7a2c3a0dde813d079fbe 530 Pfam PF05199 GMC oxidoreductase 385 519 3.7E-38 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_03195 5b8006fc11a0b5725e98efc73f1329db 438 SUPERFAMILY SSF56176 11 200 1.68E-50 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_03195 5b8006fc11a0b5725e98efc73f1329db 438 Pfam PF08031 Berberine and berberine like 395 435 2.4E-5 T 14-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 A4R43_03195 5b8006fc11a0b5725e98efc73f1329db 438 Gene3D G3DSA:3.30.465.10 100 424 2.2E-103 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_03195 5b8006fc11a0b5725e98efc73f1329db 438 Gene3D G3DSA:3.40.462.20 200 399 2.2E-103 T 14-10-2018 A4R43_03195 5b8006fc11a0b5725e98efc73f1329db 438 Pfam PF01565 FAD binding domain 36 169 7.1E-29 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_03195 5b8006fc11a0b5725e98efc73f1329db 438 Gene3D G3DSA:3.30.43.10 11 89 1.3E-25 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_19050 b6c5ebaf58b32f7bb421fe37e2a93a10 561 SUPERFAMILY SSF56672 154 560 1.11E-56 T 14-10-2018 A4R43_19050 b6c5ebaf58b32f7bb421fe37e2a93a10 561 SMART SM00482 310 519 1.5E-7 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_19050 b6c5ebaf58b32f7bb421fe37e2a93a10 561 PRINTS PR00868 DNA-polymerase family A (pol I) signature 475 491 2.7E-5 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_19050 b6c5ebaf58b32f7bb421fe37e2a93a10 561 PRINTS PR00868 DNA-polymerase family A (pol I) signature 502 515 2.7E-5 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_19050 b6c5ebaf58b32f7bb421fe37e2a93a10 561 PRINTS PR00868 DNA-polymerase family A (pol I) signature 324 347 2.7E-5 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_19050 b6c5ebaf58b32f7bb421fe37e2a93a10 561 Pfam PF00476 DNA polymerase family A 203 546 9.9E-21 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_19050 b6c5ebaf58b32f7bb421fe37e2a93a10 561 Gene3D G3DSA:1.10.150.20 333 482 6.4E-21 T 14-10-2018 A4R43_19050 b6c5ebaf58b32f7bb421fe37e2a93a10 561 Gene3D G3DSA:3.30.70.370 295 547 6.4E-21 T 14-10-2018 A4R43_11595 0155efc3516145caa18c5407de91424d 286 SUPERFAMILY SSF53686 14 286 1.87E-54 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_11595 0155efc3516145caa18c5407de91424d 286 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 2.0E-18 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_11595 0155efc3516145caa18c5407de91424d 286 PIRSF PIRSF006278 1 286 2.5E-73 T 14-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase A4R43_11595 0155efc3516145caa18c5407de91424d 286 Gene3D G3DSA:3.40.50.1100 9 284 1.8E-60 T 14-10-2018 A4R43_11595 0155efc3516145caa18c5407de91424d 286 Gene3D G3DSA:3.40.50.1100 40 141 1.8E-60 T 14-10-2018 A4R43_06600 cf1a6a5811ffad2fe669302e359e4822 260 Gene3D G3DSA:3.30.70.2650 81 168 2.2E-6 T 14-10-2018 A4R43_06600 cf1a6a5811ffad2fe669302e359e4822 260 Pfam PF07848 PaaX-like protein 2 64 1.7E-12 T 14-10-2018 IPR012906 PaaX-like, N-terminal A4R43_06600 cf1a6a5811ffad2fe669302e359e4822 260 SUPERFAMILY SSF46785 21 71 8.4E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06600 cf1a6a5811ffad2fe669302e359e4822 260 Gene3D G3DSA:1.10.10.10 1 77 3.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06600 cf1a6a5811ffad2fe669302e359e4822 260 Pfam PF08223 PaaX-like protein C-terminal domain 162 248 1.6E-10 T 14-10-2018 IPR013225 PaaX-like, C-terminal A4R43_06600 cf1a6a5811ffad2fe669302e359e4822 260 PIRSF PIRSF020623 1 260 2.3E-52 T 14-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 A4R43_19320 d4e840e266f4513ca5aa93a71205527e 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_19320 d4e840e266f4513ca5aa93a71205527e 349 Pfam PF00107 Zinc-binding dehydrogenase 176 308 1.6E-17 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_19320 d4e840e266f4513ca5aa93a71205527e 349 Gene3D G3DSA:3.40.50.720 154 292 5.4E-94 T 14-10-2018 A4R43_19320 d4e840e266f4513ca5aa93a71205527e 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 127 1.6E-32 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_19320 d4e840e266f4513ca5aa93a71205527e 349 SUPERFAMILY SSF50129 2 344 2.21E-50 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_19320 d4e840e266f4513ca5aa93a71205527e 349 SUPERFAMILY SSF51735 141 314 2.57E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19320 d4e840e266f4513ca5aa93a71205527e 349 Gene3D G3DSA:3.90.180.10 17 336 5.4E-94 T 14-10-2018 A4R43_19320 d4e840e266f4513ca5aa93a71205527e 349 SMART SM00829 10 344 6.3E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 SUPERFAMILY SSF52777 365 596 2.62E-72 T 14-10-2018 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 Pfam PF00364 Biotin-requiring enzyme 141 212 1.0E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 Pfam PF00364 Biotin-requiring enzyme 5 76 4.6E-21 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 Gene3D G3DSA:2.40.50.100 2 107 1.4E-25 T 14-10-2018 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 Gene3D G3DSA:2.40.50.100 134 235 2.4E-25 T 14-10-2018 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 Gene3D G3DSA:4.10.320.10 287 337 2.0E-16 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 369 596 1.4E-69 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 SUPERFAMILY SSF51230 1 95 2.88E-26 T 14-10-2018 IPR011053 Single hybrid motif A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 Pfam PF02817 e3 binding domain 290 324 1.4E-14 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 Gene3D G3DSA:3.30.559.10 346 602 2.8E-78 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 605 5.2E-266 T 14-10-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 SUPERFAMILY SSF47005 285 328 1.31E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 SUPERFAMILY SSF51230 140 233 2.22E-26 T 14-10-2018 IPR011053 Single hybrid motif A4R43_17825 e587eda81a235016cf6f1429c18fbcb1 605 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 164 193 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4R43_35265 3d456005d29eab2d456218788477caaa 428 SUPERFAMILY SSF47384 186 263 8.04E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_35265 3d456005d29eab2d456218788477caaa 428 SMART SM00387 308 411 1.7E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_35265 3d456005d29eab2d456218788477caaa 428 SMART SM00304 149 201 1.2E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_35265 3d456005d29eab2d456218788477caaa 428 SMART SM00388 202 266 7.7E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_35265 3d456005d29eab2d456218788477caaa 428 Gene3D G3DSA:1.10.287.130 153 266 1.3E-15 T 14-10-2018 A4R43_35265 3d456005d29eab2d456218788477caaa 428 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 407 8.4E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_35265 3d456005d29eab2d456218788477caaa 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 7.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_35265 3d456005d29eab2d456218788477caaa 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 7.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_35265 3d456005d29eab2d456218788477caaa 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 373 7.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_35265 3d456005d29eab2d456218788477caaa 428 SUPERFAMILY SSF55874 268 410 3.41E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_35265 3d456005d29eab2d456218788477caaa 428 Pfam PF00672 HAMP domain 149 196 2.1E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_35265 3d456005d29eab2d456218788477caaa 428 Gene3D G3DSA:3.30.565.10 267 412 3.2E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 Gene3D G3DSA:3.40.50.300 4 186 9.7E-44 T 14-10-2018 A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 SUPERFAMILY SSF54814 185 300 2.03E-35 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 283 5.2E-69 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 Pfam PF01926 50S ribosome-binding GTPase 11 127 2.1E-20 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 Pfam PF07650 KH domain 210 289 6.1E-18 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 Hamap MF_00367 GTPase Era [era]. 6 300 34.823 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 Gene3D G3DSA:3.30.300.20 187 300 1.7E-40 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 169 2.3E-19 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_39680 771f5b7f4fd0fb0581a647a0639b6a62 300 SUPERFAMILY SSF52540 12 219 1.4E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15865 810388c8d3fc4223ea7a71534b36c04c 372 SUPERFAMILY SSF51905 1 370 3.24E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_15865 810388c8d3fc4223ea7a71534b36c04c 372 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 365 3.1E-98 T 14-10-2018 IPR017741 FAD-dependent oxidoreductase, HpnW A4R43_15865 810388c8d3fc4223ea7a71534b36c04c 372 Pfam PF01266 FAD dependent oxidoreductase 3 367 2.2E-44 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_20690 3ea1d27a14e25fab5497d39d03a4a987 190 Pfam PF14213 STAS-like domain of unknown function (DUF4325) 37 66 4.0E-6 T 14-10-2018 IPR025474 Domain of unknown function DUF4325 A4R43_20690 3ea1d27a14e25fab5497d39d03a4a987 190 Pfam PF12802 MarR family 125 167 2.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20690 3ea1d27a14e25fab5497d39d03a4a987 190 SUPERFAMILY SSF46785 131 181 1.6E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 Gene3D G3DSA:1.20.1610.10 833 1013 5.0E-257 T 14-10-2018 A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 Pfam PF00754 F5/8 type C domain 88 205 1.1E-16 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 Gene3D G3DSA:2.70.98.10 402 738 5.0E-257 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 Gene3D G3DSA:3.30.2080.10 669 1143 5.0E-257 T 14-10-2018 A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 Gene3D G3DSA:2.60.120.260 1169 1296 7.1E-8 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 Gene3D G3DSA:2.60.120.260 80 217 5.5E-24 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 Gene3D G3DSA:1.20.1050.60 739 832 5.0E-257 T 14-10-2018 A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 Pfam PF07971 Glycosyl hydrolase family 92 609 1140 2.6E-157 T 14-10-2018 IPR012939 Glycosyl hydrolase family 92 A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 410 1142 2.5E-136 T 14-10-2018 IPR005887 Alpha-1,2-mannosidase, putative A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 SUPERFAMILY SSF49785 89 204 1.01E-16 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_09005 2bb17dcaafb552bbf07a2930f194d78b 1433 SUPERFAMILY SSF48208 633 1123 3.06E-17 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_25735 325c539a806d5f6eddff7f663aaa7d43 111 Gene3D G3DSA:3.90.1150.30 1 103 1.6E-6 T 14-10-2018 IPR038056 YjbR-like superfamily A4R43_25735 325c539a806d5f6eddff7f663aaa7d43 111 SUPERFAMILY SSF142906 6 101 7.85E-15 T 14-10-2018 IPR038056 YjbR-like superfamily A4R43_25735 325c539a806d5f6eddff7f663aaa7d43 111 Pfam PF04237 YjbR 14 102 2.5E-14 T 14-10-2018 IPR007351 Uncharacterised protein YjbR A4R43_20175 213a5841d8b8b9c131906618b448b189 309 Gene3D G3DSA:3.40.50.150 85 304 1.2E-58 T 14-10-2018 A4R43_20175 213a5841d8b8b9c131906618b448b189 309 Pfam PF00891 O-methyltransferase 89 290 1.1E-34 T 14-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 A4R43_20175 213a5841d8b8b9c131906618b448b189 309 Gene3D G3DSA:1.10.10.10 1 79 1.5E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20175 213a5841d8b8b9c131906618b448b189 309 PIRSF PIRSF005739 1 307 4.8E-25 T 14-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 A4R43_20175 213a5841d8b8b9c131906618b448b189 309 SUPERFAMILY SSF53335 89 305 6.58E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_20175 213a5841d8b8b9c131906618b448b189 309 SUPERFAMILY SSF46785 4 70 1.39E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26360 2cca182cd74456498f1b458d486cf4db 267 SUPERFAMILY SSF48498 118 266 3.67E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_26360 2cca182cd74456498f1b458d486cf4db 267 SUPERFAMILY SSF46689 46 113 8.98E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_26360 2cca182cd74456498f1b458d486cf4db 267 Gene3D G3DSA:1.10.357.10 110 265 2.4E-32 T 14-10-2018 A4R43_26360 2cca182cd74456498f1b458d486cf4db 267 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 118 262 2.7E-13 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_26360 2cca182cd74456498f1b458d486cf4db 267 Pfam PF00440 Bacterial regulatory proteins, tetR family 55 98 1.1E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_26360 2cca182cd74456498f1b458d486cf4db 267 Gene3D G3DSA:1.10.10.60 46 109 4.1E-26 T 14-10-2018 A4R43_05045 ec74133cd8000883ca4777fd76113e89 482 Pfam PF01458 Uncharacterized protein family (UPF0051) 228 453 1.2E-74 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A4R43_05045 ec74133cd8000883ca4777fd76113e89 482 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 26 473 1.7E-219 T 14-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A4R43_05045 ec74133cd8000883ca4777fd76113e89 482 SUPERFAMILY SSF101960 48 479 4.97E-138 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A4R43_26210 738eff0a3946c5a7b4dc2c1db3280301 349 Gene3D G3DSA:3.40.50.10490 198 348 9.9E-35 T 14-10-2018 A4R43_26210 738eff0a3946c5a7b4dc2c1db3280301 349 Pfam PF01380 SIS domain 49 169 1.2E-14 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_26210 738eff0a3946c5a7b4dc2c1db3280301 349 Pfam PF01380 SIS domain 209 330 8.9E-15 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_26210 738eff0a3946c5a7b4dc2c1db3280301 349 Gene3D G3DSA:3.40.50.10490 8 191 7.5E-44 T 14-10-2018 A4R43_26210 738eff0a3946c5a7b4dc2c1db3280301 349 SUPERFAMILY SSF53697 11 347 2.44E-69 T 14-10-2018 A4R43_36610 7ad0dc17af9f7337c30a714746b43ffc 689 Gene3D G3DSA:3.40.50.300 369 597 7.6E-25 T 14-10-2018 A4R43_36610 7ad0dc17af9f7337c30a714746b43ffc 689 SUPERFAMILY SSF52540 377 573 2.72E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_36610 7ad0dc17af9f7337c30a714746b43ffc 689 Pfam PF13481 AAA domain 380 523 4.3E-16 T 14-10-2018 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 SUPERFAMILY SSF55347 146 310 2.49E-45 T 14-10-2018 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 128 6.8E-25 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 SMART SM00859 4 136 5.6E-43 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 SUPERFAMILY SSF51735 3 168 1.76E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_14330 3b151deeb71932977c66c82681c4da10 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 6.3E-21 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 Gene3D G3DSA:3.30.360.10 150 315 1.1E-112 T 14-10-2018 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 Gene3D G3DSA:3.40.50.720 6 328 1.1E-112 T 14-10-2018 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 38.388 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_14330 3b151deeb71932977c66c82681c4da10 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 342 6.1E-112 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_19210 e1ff0da8aea5e8e093749950ad4e9d4d 329 Gene3D G3DSA:1.10.260.40 1 55 7.3E-19 T 14-10-2018 A4R43_19210 e1ff0da8aea5e8e093749950ad4e9d4d 329 Pfam PF13377 Periplasmic binding protein-like domain 164 324 1.3E-42 T 14-10-2018 A4R43_19210 e1ff0da8aea5e8e093749950ad4e9d4d 329 SUPERFAMILY SSF47413 1 56 3.05E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_19210 e1ff0da8aea5e8e093749950ad4e9d4d 329 Gene3D G3DSA:3.40.50.2300 156 321 4.1E-72 T 14-10-2018 A4R43_19210 e1ff0da8aea5e8e093749950ad4e9d4d 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 44 4.0E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_19210 e1ff0da8aea5e8e093749950ad4e9d4d 329 Gene3D G3DSA:3.40.50.2300 59 316 4.1E-72 T 14-10-2018 A4R43_19210 e1ff0da8aea5e8e093749950ad4e9d4d 329 SUPERFAMILY SSF53822 59 327 3.62E-65 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_19210 e1ff0da8aea5e8e093749950ad4e9d4d 329 SMART SM00354 1 68 2.4E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_23875 dc95b87479319c0df03d29bb16d815ee 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 1.5E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_23875 dc95b87479319c0df03d29bb16d815ee 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 6.2E-27 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_23875 dc95b87479319c0df03d29bb16d815ee 327 SMART SM00382 33 233 2.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_23875 dc95b87479319c0df03d29bb16d815ee 327 Gene3D G3DSA:3.40.50.300 1 327 3.0E-99 T 14-10-2018 A4R43_23875 dc95b87479319c0df03d29bb16d815ee 327 SUPERFAMILY SSF52540 4 254 2.08E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23875 dc95b87479319c0df03d29bb16d815ee 327 Pfam PF00005 ABC transporter 24 183 9.6E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23875 dc95b87479319c0df03d29bb16d815ee 327 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_31715 78adc3bde80ccb009493050bffd568c6 627 SMART SM00220 15 267 1.5E-33 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_31715 78adc3bde80ccb009493050bffd568c6 627 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_31715 78adc3bde80ccb009493050bffd568c6 627 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_31715 78adc3bde80ccb009493050bffd568c6 627 Gene3D G3DSA:3.30.200.20 6 93 2.1E-15 T 14-10-2018 A4R43_31715 78adc3bde80ccb009493050bffd568c6 627 Pfam PF00069 Protein kinase domain 15 262 1.2E-34 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_31715 78adc3bde80ccb009493050bffd568c6 627 Gene3D G3DSA:1.10.510.10 95 271 2.3E-42 T 14-10-2018 A4R43_31715 78adc3bde80ccb009493050bffd568c6 627 SUPERFAMILY SSF56112 12 303 8.25E-60 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_21840 42ab221228b24d77a1bf232079dabef2 414 Gene3D G3DSA:3.40.50.2000 4 397 8.9E-107 T 14-10-2018 A4R43_21840 42ab221228b24d77a1bf232079dabef2 414 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 132 8.1E-9 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_21840 42ab221228b24d77a1bf232079dabef2 414 Gene3D G3DSA:3.40.50.2000 227 396 8.9E-107 T 14-10-2018 A4R43_21840 42ab221228b24d77a1bf232079dabef2 414 SUPERFAMILY SSF53756 1 413 2.14E-89 T 14-10-2018 A4R43_21840 42ab221228b24d77a1bf232079dabef2 414 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 237 393 7.0E-7 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_33275 bab5df69fcb6b76f8199164837ce0001 416 SUPERFAMILY SSF103473 23 411 7.32E-43 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_33275 bab5df69fcb6b76f8199164837ce0001 416 Gene3D G3DSA:1.20.1250.20 21 409 5.7E-30 T 14-10-2018 A4R43_33275 bab5df69fcb6b76f8199164837ce0001 416 Pfam PF07690 Major Facilitator Superfamily 32 277 1.2E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_28250 b09bc5a533ee699f91ac03723fee8d0f 368 Gene3D G3DSA:3.90.1150.10 237 367 8.7E-33 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_28250 b09bc5a533ee699f91ac03723fee8d0f 368 PIRSF PIRSF000390 1 368 1.5E-107 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_28250 b09bc5a533ee699f91ac03723fee8d0f 368 SUPERFAMILY SSF53383 12 367 4.98E-109 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_28250 b09bc5a533ee699f91ac03723fee8d0f 368 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 363 1.3E-118 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_28250 b09bc5a533ee699f91ac03723fee8d0f 368 Gene3D G3DSA:3.40.640.10 7 236 4.8E-88 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_01645 5135cfe01ecfbe3bbb4a22960da5730c 343 Gene3D G3DSA:1.10.10.10 1 94 1.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01645 5135cfe01ecfbe3bbb4a22960da5730c 343 PIRSF PIRSF005739 2 340 4.3E-47 T 14-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 A4R43_01645 5135cfe01ecfbe3bbb4a22960da5730c 343 Gene3D G3DSA:3.40.50.150 95 341 1.8E-69 T 14-10-2018 A4R43_01645 5135cfe01ecfbe3bbb4a22960da5730c 343 SUPERFAMILY SSF53335 92 340 3.64E-51 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_01645 5135cfe01ecfbe3bbb4a22960da5730c 343 Pfam PF00891 O-methyltransferase 105 322 1.5E-43 T 14-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 A4R43_01645 5135cfe01ecfbe3bbb4a22960da5730c 343 SUPERFAMILY SSF46785 10 91 1.77E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_30460 682cb8ad7b38be3f0a5977f961dab4f6 326 Gene3D G3DSA:1.10.10.2830 135 248 3.8E-35 T 14-10-2018 A4R43_30460 682cb8ad7b38be3f0a5977f961dab4f6 326 SUPERFAMILY SSF109709 140 249 9.68E-32 T 14-10-2018 A4R43_30460 682cb8ad7b38be3f0a5977f961dab4f6 326 Pfam PF02195 ParB-like nuclease domain 59 148 4.2E-25 T 14-10-2018 IPR003115 ParB/Sulfiredoxin A4R43_30460 682cb8ad7b38be3f0a5977f961dab4f6 326 Gene3D G3DSA:3.90.1530.30 71 133 5.7E-25 T 14-10-2018 A4R43_30460 682cb8ad7b38be3f0a5977f961dab4f6 326 SMART SM00470 58 148 1.1E-33 T 14-10-2018 IPR003115 ParB/Sulfiredoxin A4R43_30460 682cb8ad7b38be3f0a5977f961dab4f6 326 SUPERFAMILY SSF110849 54 151 2.49E-28 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A4R43_30460 682cb8ad7b38be3f0a5977f961dab4f6 326 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 56 233 1.3E-62 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A4R43_35535 f121af715c43b162e93438212530aaa0 326 Gene3D G3DSA:3.30.60.70 121 160 1.4E-24 T 14-10-2018 IPR038361 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain superfamily KEGG: 00300+2.3.1.117 A4R43_35535 f121af715c43b162e93438212530aaa0 326 Gene3D G3DSA:3.30.70.2010 5 120 1.8E-40 T 14-10-2018 A4R43_35535 f121af715c43b162e93438212530aaa0 326 SUPERFAMILY SSF51161 91 305 4.16E-36 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_35535 f121af715c43b162e93438212530aaa0 326 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 9 324 43.254 T 14-10-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 A4R43_35535 f121af715c43b162e93438212530aaa0 326 Gene3D G3DSA:2.160.10.10 161 326 4.2E-66 T 14-10-2018 A4R43_35535 f121af715c43b162e93438212530aaa0 326 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 121 160 1.2E-20 T 14-10-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 A4R43_35535 f121af715c43b162e93438212530aaa0 326 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 11 326 2.0E-153 T 14-10-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 A4R43_35535 f121af715c43b162e93438212530aaa0 326 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 242 274 8.5E-14 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_36565 fe888011dcc6b18e00d197cbcfb1b05c 155 Gene3D G3DSA:3.30.1360.200 40 153 1.0E-20 T 14-10-2018 A4R43_03260 b52bc7157283f1cdd17ffc478632dcac 153 Pfam PF00578 AhpC/TSA family 5 126 8.1E-20 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_03260 b52bc7157283f1cdd17ffc478632dcac 153 SUPERFAMILY SSF52833 2 149 2.68E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_03260 b52bc7157283f1cdd17ffc478632dcac 153 Gene3D G3DSA:3.40.30.10 1 151 8.5E-28 T 14-10-2018 A4R43_06960 ff2440db5aa16fdc0d90c90df4e74e81 64 Gene3D G3DSA:3.30.70.20 1 63 9.2E-18 T 14-10-2018 A4R43_06960 ff2440db5aa16fdc0d90c90df4e74e81 64 SUPERFAMILY SSF54862 2 62 2.15E-11 T 14-10-2018 A4R43_06960 ff2440db5aa16fdc0d90c90df4e74e81 64 Pfam PF13459 4Fe-4S single cluster domain 3 62 8.8E-12 T 14-10-2018 A4R43_33385 74db4ee22fb9aca3a6b512f3e61cb2c7 285 Pfam PF01435 Peptidase family M48 68 282 3.7E-36 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4R43_33385 74db4ee22fb9aca3a6b512f3e61cb2c7 285 Hamap MF_00188 Protease HtpX [htpX]. 7 282 27.043 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A4R43_33385 74db4ee22fb9aca3a6b512f3e61cb2c7 285 Gene3D G3DSA:3.30.2010.10 60 150 3.4E-27 T 14-10-2018 A4R43_05115 e76d2812e78c3ce858f25d90526f15b5 952 Pfam PF00082 Subtilase family 265 628 5.8E-17 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_05115 e76d2812e78c3ce858f25d90526f15b5 952 SUPERFAMILY SSF49785 809 930 4.68E-7 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_05115 e76d2812e78c3ce858f25d90526f15b5 952 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 589 599 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_05115 e76d2812e78c3ce858f25d90526f15b5 952 SUPERFAMILY SSF52743 196 651 1.2E-33 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_05115 e76d2812e78c3ce858f25d90526f15b5 952 Gene3D G3DSA:3.40.50.200 199 367 9.9E-10 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_05115 e76d2812e78c3ce858f25d90526f15b5 952 Pfam PF01483 Proprotein convertase P-domain 822 926 1.5E-5 T 14-10-2018 IPR002884 P domain GO:0004252|GO:0006508 A4R43_11280 b62a259ffc84c827dc94a36cb33a6749 571 Gene3D G3DSA:3.30.300.310 449 554 2.4E-23 T 14-10-2018 A4R43_11280 b62a259ffc84c827dc94a36cb33a6749 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 462 539 3.5E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_11280 b62a259ffc84c827dc94a36cb33a6749 571 SUPERFAMILY SSF56801 21 550 1.07E-129 T 14-10-2018 A4R43_11280 b62a259ffc84c827dc94a36cb33a6749 571 Pfam PF00501 AMP-binding enzyme 62 453 3.6E-72 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_11280 b62a259ffc84c827dc94a36cb33a6749 571 Gene3D G3DSA:3.40.50.12780 20 446 3.1E-112 T 14-10-2018 A4R43_30835 69b186a2ea79ab31622ec6440bbf89ef 361 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 8 357 1.2E-211 T 14-10-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria A4R43_30835 69b186a2ea79ab31622ec6440bbf89ef 361 Gene3D G3DSA:3.40.50.720 8 356 3.3E-150 T 14-10-2018 A4R43_30835 69b186a2ea79ab31622ec6440bbf89ef 361 Gene3D G3DSA:3.30.360.10 194 303 3.3E-150 T 14-10-2018 A4R43_30835 69b186a2ea79ab31622ec6440bbf89ef 361 SUPERFAMILY SSF55347 194 302 3.4E-35 T 14-10-2018 A4R43_30835 69b186a2ea79ab31622ec6440bbf89ef 361 Pfam PF01658 Myo-inositol-1-phosphate synthase 195 303 5.0E-33 T 14-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A4R43_30835 69b186a2ea79ab31622ec6440bbf89ef 361 SUPERFAMILY SSF51735 7 359 2.6E-94 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_30835 69b186a2ea79ab31622ec6440bbf89ef 361 PIRSF PIRSF015578 1 361 9.1E-95 T 14-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A4R43_04515 7e2a3d60de058142792f64d89b84b009 293 SMART SM00530 21 76 1.7E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_04515 7e2a3d60de058142792f64d89b84b009 293 Gene3D G3DSA:1.10.260.40 13 80 1.1E-6 T 14-10-2018 A4R43_04515 7e2a3d60de058142792f64d89b84b009 293 SUPERFAMILY SSF47413 15 73 3.38E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_04515 7e2a3d60de058142792f64d89b84b009 293 Pfam PF13560 Helix-turn-helix domain 18 79 1.4E-12 T 14-10-2018 A4R43_08445 c1db3dd89fa34a38f928f3804d339145 257 Gene3D G3DSA:1.10.8.10 3 67 2.4E-5 T 14-10-2018 A4R43_08445 c1db3dd89fa34a38f928f3804d339145 257 Pfam PF05175 Methyltransferase small domain 68 169 9.8E-12 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A4R43_08445 c1db3dd89fa34a38f928f3804d339145 257 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 37 227 1.3E-45 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A4R43_08445 c1db3dd89fa34a38f928f3804d339145 257 Gene3D G3DSA:3.40.50.150 68 246 8.4E-47 T 14-10-2018 A4R43_08445 c1db3dd89fa34a38f928f3804d339145 257 SUPERFAMILY SSF53335 46 221 7.99E-45 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_08445 c1db3dd89fa34a38f928f3804d339145 257 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 10 255 1.9E-119 T 14-10-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase A4R43_01570 2e9d669f980eaf278ee99dd3c1222660 234 SUPERFAMILY SSF48498 89 233 7.03E-28 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_01570 2e9d669f980eaf278ee99dd3c1222660 234 Gene3D G3DSA:1.10.357.10 79 233 2.8E-40 T 14-10-2018 A4R43_01570 2e9d669f980eaf278ee99dd3c1222660 234 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 83 231 9.8E-24 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_01570 2e9d669f980eaf278ee99dd3c1222660 234 Gene3D G3DSA:1.10.10.60 1 76 7.0E-25 T 14-10-2018 A4R43_01570 2e9d669f980eaf278ee99dd3c1222660 234 SUPERFAMILY SSF46689 17 77 9.48E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01570 2e9d669f980eaf278ee99dd3c1222660 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 71 4.9E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_27715 495fa9285e739f53e02ba2517fbe6490 164 PIRSF PIRSF006092 7 163 1.1E-18 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A4R43_27715 495fa9285e739f53e02ba2517fbe6490 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 93 159 9.1E-13 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4R43_27715 495fa9285e739f53e02ba2517fbe6490 164 Pfam PF03449 Transcription elongation factor, N-terminal 12 76 3.5E-5 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4R43_27715 495fa9285e739f53e02ba2517fbe6490 164 Gene3D G3DSA:3.10.50.30 92 163 7.7E-13 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 A4R43_27715 495fa9285e739f53e02ba2517fbe6490 164 SUPERFAMILY SSF54534 93 159 3.27E-11 T 14-10-2018 A4R43_32035 5703c3b2e03f9591a07915218795a3b9 282 Gene3D G3DSA:3.30.470.10 2 110 2.2E-30 T 14-10-2018 A4R43_32035 5703c3b2e03f9591a07915218795a3b9 282 Pfam PF01063 Amino-transferase class IV 31 256 9.4E-42 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A4R43_32035 5703c3b2e03f9591a07915218795a3b9 282 Gene3D G3DSA:3.20.10.10 118 281 6.3E-51 T 14-10-2018 A4R43_32035 5703c3b2e03f9591a07915218795a3b9 282 SUPERFAMILY SSF56752 4 279 7.98E-55 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A4R43_14580 3d76ed811d7c9b83f07610a95c80a32e 164 Gene3D G3DSA:2.60.40.2880 75 163 1.4E-15 T 14-10-2018 IPR038468 Transport accessory protein MmpS, soluble domain superfamily A4R43_14580 3d76ed811d7c9b83f07610a95c80a32e 164 Pfam PF05423 Mycobacterium membrane protein 33 160 1.1E-12 T 14-10-2018 IPR008693 Transport accessory protein MmpS A4R43_08290 afec5780f8259b6a6379bebedebc2928 207 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 156 206 3.2E-6 T 14-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type A4R43_08290 afec5780f8259b6a6379bebedebc2928 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 1.9E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08290 afec5780f8259b6a6379bebedebc2928 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 3.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08290 afec5780f8259b6a6379bebedebc2928 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 3.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08290 afec5780f8259b6a6379bebedebc2928 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 66 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_08290 afec5780f8259b6a6379bebedebc2928 207 SUPERFAMILY SSF46689 11 88 5.99E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08290 afec5780f8259b6a6379bebedebc2928 207 Gene3D G3DSA:1.10.357.10 9 207 9.9E-40 T 14-10-2018 A4R43_24025 79f2af822e317f9f9375974db71fd6b6 282 Pfam PF00296 Luciferase-like monooxygenase 16 256 4.8E-27 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_24025 79f2af822e317f9f9375974db71fd6b6 282 SUPERFAMILY SSF51679 3 278 5.5E-43 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_24025 79f2af822e317f9f9375974db71fd6b6 282 Gene3D G3DSA:3.20.20.30 10 281 1.0E-40 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_24025 79f2af822e317f9f9375974db71fd6b6 282 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 4 281 6.9E-87 T 14-10-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted A4R43_13990 e753ff1559dc56e64d11aa63119b91ca 492 SUPERFAMILY SSF53720 3 479 6.94E-164 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_13990 e753ff1559dc56e64d11aa63119b91ca 492 Pfam PF00171 Aldehyde dehydrogenase family 10 475 2.6E-167 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_13990 e753ff1559dc56e64d11aa63119b91ca 492 Gene3D G3DSA:3.40.605.10 9 469 3.4E-179 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_13990 e753ff1559dc56e64d11aa63119b91ca 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_13990 e753ff1559dc56e64d11aa63119b91ca 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_13990 e753ff1559dc56e64d11aa63119b91ca 492 Gene3D G3DSA:3.40.309.10 252 445 3.4E-179 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 Gene3D G3DSA:2.60.120.260 362 561 5.9E-38 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 327 529 7.7E-33 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 Gene3D G3DSA:3.40.50.1820 21 339 1.1E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 SMART SM00939 317 533 6.3E-32 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 239 557 1.7E-35 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 23 148 4.6E-47 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 Gene3D G3DSA:1.10.3020.10 154 235 1.1E-62 T 14-10-2018 A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 SUPERFAMILY SSF53474 20 339 5.18E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 27 283 7.1E-39 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4R43_09515 fa45da50aeab4ace0fb5e9a49bf6629c 564 SUPERFAMILY SSF49785 348 558 2.13E-37 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_03910 e472dfb607d36803b10de251dcb52be3 225 SUPERFAMILY SSF46785 12 197 4.01E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03910 e472dfb607d36803b10de251dcb52be3 225 Gene3D G3DSA:1.10.10.10 5 97 9.0E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03910 e472dfb607d36803b10de251dcb52be3 225 Pfam PF12840 Helix-turn-helix domain 14 71 3.1E-8 T 14-10-2018 A4R43_40640 da81f74e2616fc2e9d8c5c3b64e63cfa 218 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 217 3.7E-69 T 14-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like A4R43_36535 fcd126a5180cfb10c61edf0c95fd30f1 211 SUPERFAMILY SSF46689 10 88 1.95E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_36535 fcd126a5180cfb10c61edf0c95fd30f1 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 62 4.9E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36535 fcd126a5180cfb10c61edf0c95fd30f1 211 Gene3D G3DSA:1.10.357.10 7 184 3.5E-42 T 14-10-2018 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 SUPERFAMILY SSF46609 3 88 3.8E-29 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 4.7E-19 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 4.7E-19 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 4.7E-19 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 4.7E-19 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 4.7E-19 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 Gene3D G3DSA:2.40.500.20 85 207 5.1E-42 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 PIRSF PIRSF000349 1 202 8.0E-70 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 1.1E-29 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 2.2E-33 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 SUPERFAMILY SSF54719 84 197 4.45E-41 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 Gene3D G3DSA:1.10.287.990 21 84 1.2E-22 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_25765 fc04e0fd712af9462cb810fe5e4a8047 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4R43_37945 8eafeca3b7d6268f7ce9c1c6c37ab8c0 275 Gene3D G3DSA:1.10.12.10 217 275 2.2E-22 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_37945 8eafeca3b7d6268f7ce9c1c6c37ab8c0 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_37945 8eafeca3b7d6268f7ce9c1c6c37ab8c0 275 Gene3D G3DSA:3.90.226.10 2 216 2.8E-72 T 14-10-2018 A4R43_37945 8eafeca3b7d6268f7ce9c1c6c37ab8c0 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 274 1.1E-46 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_37945 8eafeca3b7d6268f7ce9c1c6c37ab8c0 275 SUPERFAMILY SSF52096 14 275 1.99E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 Gene3D G3DSA:3.40.50.2300 2 128 2.8E-19 T 14-10-2018 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 Gene3D G3DSA:1.10.10.10 129 198 5.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 SUPERFAMILY SSF46894 125 197 1.94E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 SMART SM00448 2 115 5.9E-7 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 SMART SM00421 134 191 6.1E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 Pfam PF00072 Response regulator receiver domain 4 115 2.2E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 189 2.2E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 SUPERFAMILY SSF52172 3 123 1.57E-16 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 8.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 8.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34325 1dd3ed32ce6e561d403204d8b03c23e5 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 8.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_01745 fa49bcbb69900e3dc6ae8fc3eb5e987b 437 PIRSF PIRSF000521 14 160 7.9E-10 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_01745 fa49bcbb69900e3dc6ae8fc3eb5e987b 437 PIRSF PIRSF000521 171 431 1.9E-25 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_01745 fa49bcbb69900e3dc6ae8fc3eb5e987b 437 Gene3D G3DSA:3.90.1150.10 19 426 3.7E-133 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_01745 fa49bcbb69900e3dc6ae8fc3eb5e987b 437 Pfam PF00202 Aminotransferase class-III 32 428 1.2E-95 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_01745 fa49bcbb69900e3dc6ae8fc3eb5e987b 437 SUPERFAMILY SSF53383 20 429 4.08E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_01745 fa49bcbb69900e3dc6ae8fc3eb5e987b 437 Gene3D G3DSA:3.40.640.10 68 333 3.7E-133 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_01745 fa49bcbb69900e3dc6ae8fc3eb5e987b 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 SUPERFAMILY SSF54826 14 113 8.84E-31 T 14-10-2018 A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 Pfam PF13378 Enolase C-terminal domain-like 190 377 7.6E-45 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 17 111 1.0E-30 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 Gene3D G3DSA:3.20.20.120 106 366 7.2E-156 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 207 238 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 Gene3D G3DSA:3.30.390.10 7 398 7.2E-156 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 SUPERFAMILY SSF51604 99 386 6.55E-75 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 SMART SM00922 130 257 3.2E-18 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_02385 7611c0531f64c72413e7fdaeaf70d862 402 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 86 111 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4R43_20795 8042bbd3dccbc04e2c0e038333b81e70 218 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 122 8.1E-22 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4R43_20795 8042bbd3dccbc04e2c0e038333b81e70 218 SUPERFAMILY SSF102588 6 211 1.57E-41 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_20795 8042bbd3dccbc04e2c0e038333b81e70 218 Gene3D G3DSA:3.40.50.10320 3 215 8.7E-45 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_16005 16ea0794b0fe95e2f765b8f86c5a17eb 279 SUPERFAMILY SSF52096 2 254 3.27E-65 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_16005 16ea0794b0fe95e2f765b8f86c5a17eb 279 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 240 6.5E-40 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_16005 16ea0794b0fe95e2f765b8f86c5a17eb 279 Gene3D G3DSA:3.90.226.10 1 274 4.3E-85 T 14-10-2018 A4R43_32200 998c4d2fae7d0b38e78ee37468b3b8aa 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 314 1.3E-5 T 14-10-2018 A4R43_32200 998c4d2fae7d0b38e78ee37468b3b8aa 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.3E-5 T 14-10-2018 A4R43_32200 998c4d2fae7d0b38e78ee37468b3b8aa 488 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 72 2.0E-7 T 14-10-2018 A4R43_32200 998c4d2fae7d0b38e78ee37468b3b8aa 488 Gene3D G3DSA:3.50.50.60 1 85 3.9E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_32200 998c4d2fae7d0b38e78ee37468b3b8aa 488 SUPERFAMILY SSF51905 5 471 2.59E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_25330 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF46689 7 116 2.75E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25330 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF13551 Winged helix-turn helix 10 51 1.4E-6 T 14-10-2018 A4R43_25330 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF53098 131 302 2.53E-29 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_25330 12899d22ffd0e126500ca69d01e3e06b 389 Gene3D G3DSA:3.30.420.10 135 303 1.4E-25 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_25330 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF00665 Integrase core domain 137 258 8.1E-24 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_25935 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF46689 7 116 2.75E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25935 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF13551 Winged helix-turn helix 10 51 1.4E-6 T 14-10-2018 A4R43_25935 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF53098 131 302 2.53E-29 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_25935 12899d22ffd0e126500ca69d01e3e06b 389 Gene3D G3DSA:3.30.420.10 135 303 1.4E-25 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_25935 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF00665 Integrase core domain 137 258 8.1E-24 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_06360 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF46689 7 116 2.75E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_06360 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF13551 Winged helix-turn helix 10 51 1.4E-6 T 14-10-2018 A4R43_06360 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF53098 131 302 2.53E-29 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_06360 12899d22ffd0e126500ca69d01e3e06b 389 Gene3D G3DSA:3.30.420.10 135 303 1.4E-25 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_06360 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF00665 Integrase core domain 137 258 8.1E-24 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_14425 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF46689 7 116 2.75E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14425 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF13551 Winged helix-turn helix 10 51 1.4E-6 T 14-10-2018 A4R43_14425 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF53098 131 302 2.53E-29 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_14425 12899d22ffd0e126500ca69d01e3e06b 389 Gene3D G3DSA:3.30.420.10 135 303 1.4E-25 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_14425 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF00665 Integrase core domain 137 258 8.1E-24 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_34615 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF46689 7 116 2.75E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_34615 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF13551 Winged helix-turn helix 10 51 1.4E-6 T 14-10-2018 A4R43_34615 12899d22ffd0e126500ca69d01e3e06b 389 SUPERFAMILY SSF53098 131 302 2.53E-29 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_34615 12899d22ffd0e126500ca69d01e3e06b 389 Gene3D G3DSA:3.30.420.10 135 303 1.4E-25 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_34615 12899d22ffd0e126500ca69d01e3e06b 389 Pfam PF00665 Integrase core domain 137 258 8.1E-24 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 Pfam PF00196 Bacterial regulatory proteins, luxR family 794 847 4.5E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 Gene3D G3DSA:1.10.10.10 773 850 4.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 Pfam PF13191 AAA ATPase domain 5 151 1.8E-15 T 14-10-2018 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 809 825 5.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 795 809 5.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 825 837 5.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 ProSitePatterns PS00622 LuxR-type HTH domain signature. 809 836 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 SMART SM00421 792 849 8.3E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 SUPERFAMILY SSF46894 785 846 7.82E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 SUPERFAMILY SSF48452 329 435 5.69E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_06055 daaa0383653e0de3bbe6b35413e5be80 852 SUPERFAMILY SSF52540 20 158 6.82E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13435 cdb048dba12e1bf5a633e2a0161f00e4 262 Pfam PF10703 MoaF N-terminal domain 10 112 2.4E-28 T 14-10-2018 IPR024724 Molybdenum cofactor biosynthesis protein F, N-terminal A4R43_13435 cdb048dba12e1bf5a633e2a0161f00e4 262 Pfam PF17409 MoaF C-terminal domain 138 252 1.3E-45 T 14-10-2018 IPR035348 MoaF, C-terminal domain A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 1.9E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 PIRSF PIRSF000532 1 339 1.4E-119 T 14-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4R43_16320 9db763aef02ca1498005597de509cb09 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 44.308 T 14-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4R43_16320 9db763aef02ca1498005597de509cb09 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 6.9E-151 T 14-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4R43_16320 9db763aef02ca1498005597de509cb09 341 Gene3D G3DSA:3.40.50.460 140 277 8.1E-112 T 14-10-2018 A4R43_16320 9db763aef02ca1498005597de509cb09 341 SUPERFAMILY SSF53784 1 331 1.96E-121 T 14-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 14-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_16320 9db763aef02ca1498005597de509cb09 341 Gene3D G3DSA:3.40.50.450 3 322 8.1E-112 T 14-10-2018 A4R43_16320 9db763aef02ca1498005597de509cb09 341 Pfam PF00365 Phosphofructokinase 2 296 6.1E-103 T 14-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4R43_33960 1931122b22f526c877990117020c16c6 259 Pfam PF00557 Metallopeptidase family M24 11 247 5.4E-46 T 14-10-2018 IPR000994 Peptidase M24 A4R43_33960 1931122b22f526c877990117020c16c6 259 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 255 1.2E-83 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_33960 1931122b22f526c877990117020c16c6 259 SUPERFAMILY SSF55920 1 254 1.96E-78 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like A4R43_33960 1931122b22f526c877990117020c16c6 259 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_33960 1931122b22f526c877990117020c16c6 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 1.9E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_33960 1931122b22f526c877990117020c16c6 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.9E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_33960 1931122b22f526c877990117020c16c6 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.9E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_33960 1931122b22f526c877990117020c16c6 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 198 210 1.9E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_33960 1931122b22f526c877990117020c16c6 259 Hamap MF_01974 Methionine aminopeptidase [map]. 2 256 38.252 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_33960 1931122b22f526c877990117020c16c6 259 Gene3D G3DSA:3.90.230.10 1 256 4.6E-92 T 14-10-2018 A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 SUPERFAMILY SSF53850 3 184 9.34E-48 T 14-10-2018 A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 SUPERFAMILY SSF55021 174 269 8.33E-22 T 14-10-2018 A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 PIRSF PIRSF001500 1 272 1.1E-61 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 Gene3D G3DSA:3.30.70.260 180 276 4.4E-28 T 14-10-2018 A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 Pfam PF01842 ACT domain 195 255 1.2E-8 T 14-10-2018 IPR002912 ACT domain A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 Gene3D G3DSA:3.40.190.10 1 88 4.7E-29 T 14-10-2018 A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 Pfam PF00800 Prephenate dehydratase 4 176 2.5E-49 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 153 175 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4R43_28430 5fd19e80be7dd8e41e09c3162ddf786e 302 Gene3D G3DSA:3.40.190.10 89 167 7.7E-22 T 14-10-2018 A4R43_37820 a4c0b8c2cf8be0456c51709ea87e823a 298 Pfam PF13602 Zinc-binding dehydrogenase 195 296 3.1E-12 T 14-10-2018 A4R43_37820 a4c0b8c2cf8be0456c51709ea87e823a 298 SUPERFAMILY SSF50129 1 147 1.98E-29 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_37820 a4c0b8c2cf8be0456c51709ea87e823a 298 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A4R43_37820 a4c0b8c2cf8be0456c51709ea87e823a 298 SUPERFAMILY SSF51735 111 235 5.6E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37820 a4c0b8c2cf8be0456c51709ea87e823a 298 Gene3D G3DSA:3.90.180.10 8 294 3.0E-74 T 14-10-2018 A4R43_37820 a4c0b8c2cf8be0456c51709ea87e823a 298 Gene3D G3DSA:3.40.50.720 122 247 3.0E-74 T 14-10-2018 A4R43_37820 a4c0b8c2cf8be0456c51709ea87e823a 298 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 8.6E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_37820 a4c0b8c2cf8be0456c51709ea87e823a 298 SMART SM00829 10 296 2.8E-12 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_00745 991a051b5d73b60c404777429de37257 215 Pfam PF01872 RibD C-terminal domain 9 188 3.8E-12 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_00745 991a051b5d73b60c404777429de37257 215 Gene3D G3DSA:3.40.430.10 3 211 3.4E-36 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_00745 991a051b5d73b60c404777429de37257 215 SUPERFAMILY SSF53597 58 213 2.88E-25 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_00770 6578b5525a9ffe3cfdd705a224be25db 513 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 330 512 4.8E-18 T 14-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 A4R43_00770 6578b5525a9ffe3cfdd705a224be25db 513 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 111 244 2.7E-14 T 14-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 A4R43_31200 66cf16556bd0ed1e9d6064ba19bde500 616 Pfam PF12229 Putative peptidoglycan binding domain 293 367 1.3E-9 T 14-10-2018 IPR022029 Putative peptidoglycan binding domain A4R43_31200 66cf16556bd0ed1e9d6064ba19bde500 616 Pfam PF04294 VanW like protein 413 542 5.8E-36 T 14-10-2018 IPR007391 Vancomycin resistance VanW A4R43_00655 a5618491d70a5f095cd6777b8270ae5c 276 Gene3D G3DSA:3.40.50.720 1 151 1.1E-34 T 14-10-2018 A4R43_00655 a5618491d70a5f095cd6777b8270ae5c 276 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 150 5.8E-17 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_00655 a5618491d70a5f095cd6777b8270ae5c 276 PIRSF PIRSF000103 1 276 3.1E-29 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_00655 a5618491d70a5f095cd6777b8270ae5c 276 Gene3D G3DSA:1.10.1040.10 153 276 1.6E-27 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_00655 a5618491d70a5f095cd6777b8270ae5c 276 SUPERFAMILY SSF51735 1 151 3.04E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_23280 e4ccccee8328a2d37dcfb7212534c4ef 78 SUPERFAMILY SSF158997 4 63 1.44E-14 T 14-10-2018 A4R43_23280 e4ccccee8328a2d37dcfb7212534c4ef 78 Pfam PF03966 Trm112p-like protein 6 50 1.6E-8 T 14-10-2018 IPR005651 Trm112-like A4R43_23280 e4ccccee8328a2d37dcfb7212534c4ef 78 Gene3D G3DSA:2.20.25.10 12 73 1.8E-16 T 14-10-2018 A4R43_10700 3b6e35e5f1ae55ab63e5e9e95cef26ce 405 SUPERFAMILY SSF55729 7 301 1.37E-47 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_10700 3b6e35e5f1ae55ab63e5e9e95cef26ce 405 Pfam PF13530 Sterol carrier protein domain 184 401 2.4E-48 T 14-10-2018 IPR025559 Enhanced intracellular survival protein domain A4R43_10700 3b6e35e5f1ae55ab63e5e9e95cef26ce 405 Hamap MF_01812 N-acetyltransferase Eis [eis]. 3 405 31.293 T 14-10-2018 IPR022902 N-acetyltransferase Eis A4R43_10700 3b6e35e5f1ae55ab63e5e9e95cef26ce 405 SUPERFAMILY SSF55718 302 405 7.85E-21 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_10700 3b6e35e5f1ae55ab63e5e9e95cef26ce 405 Gene3D G3DSA:3.40.630.30 138 294 4.8E-35 T 14-10-2018 A4R43_10700 3b6e35e5f1ae55ab63e5e9e95cef26ce 405 Pfam PF13527 Acetyltransferase (GNAT) domain 7 134 6.8E-25 T 14-10-2018 A4R43_10700 3b6e35e5f1ae55ab63e5e9e95cef26ce 405 Gene3D G3DSA:3.30.1050.10 300 395 2.0E-24 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_10700 3b6e35e5f1ae55ab63e5e9e95cef26ce 405 Gene3D G3DSA:3.40.630.30 1 137 6.7E-31 T 14-10-2018 A4R43_23930 bbf7fd0b7ddce108355ffae6887ba525 133 Gene3D G3DSA:1.25.40.10 15 128 7.3E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_23930 bbf7fd0b7ddce108355ffae6887ba525 133 SUPERFAMILY SSF48452 9 111 5.27E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_23930 bbf7fd0b7ddce108355ffae6887ba525 133 Pfam PF14559 Tetratricopeptide repeat 23 83 8.4E-9 T 14-10-2018 A4R43_35305 01dc0a1d3ef4223264a830149dd66cdc 165 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 156 32.946 T 14-10-2018 IPR033747 Class I PurE A4R43_35305 01dc0a1d3ef4223264a830149dd66cdc 165 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 1.4E-65 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4R43_35305 01dc0a1d3ef4223264a830149dd66cdc 165 SMART SM01001 3 152 2.2E-96 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4R43_35305 01dc0a1d3ef4223264a830149dd66cdc 165 SUPERFAMILY SSF52255 4 162 9.81E-67 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A4R43_35305 01dc0a1d3ef4223264a830149dd66cdc 165 Pfam PF00731 AIR carboxylase 5 149 3.6E-66 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4R43_35305 01dc0a1d3ef4223264a830149dd66cdc 165 PIRSF PIRSF001338 1 163 4.1E-69 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A4R43_35305 01dc0a1d3ef4223264a830149dd66cdc 165 Gene3D G3DSA:3.40.50.7700 1 165 3.1E-74 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A4R43_04115 d25e2250a93721096a52019af6af4659 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 50 5.8E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_04115 d25e2250a93721096a52019af6af4659 194 Gene3D G3DSA:1.10.1040.10 90 191 1.7E-24 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_04115 d25e2250a93721096a52019af6af4659 194 SUPERFAMILY SSF46689 3 54 2.77E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_04115 d25e2250a93721096a52019af6af4659 194 Gene3D G3DSA:1.10.10.60 1 52 9.0E-9 T 14-10-2018 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 SUPERFAMILY SSF52172 2 130 7.4E-26 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 SUPERFAMILY SSF46894 125 201 4.76E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 Gene3D G3DSA:3.40.50.12740 2 200 1.4E-51 T 14-10-2018 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 Pfam PF00072 Response regulator receiver domain 4 113 2.4E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 SMART SM00448 2 115 2.1E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 SMART SM00421 138 195 3.1E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 6.6E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 9.4E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 9.4E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27725 c84a7b8fb178883fd91ad557a11209f1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 9.4E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_17225 67e12d4d6a8c0b4c07ddde745c575095 263 Gene3D G3DSA:3.20.20.70 1 260 1.6E-87 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17225 67e12d4d6a8c0b4c07ddde745c575095 263 SUPERFAMILY SSF51366 2 250 2.75E-78 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4R43_17225 67e12d4d6a8c0b4c07ddde745c575095 263 Pfam PF00290 Tryptophan synthase alpha chain 8 244 7.3E-70 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4R43_17225 67e12d4d6a8c0b4c07ddde745c575095 263 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 9 245 3.2E-62 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4R43_17225 67e12d4d6a8c0b4c07ddde745c575095 263 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 255 32.076 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4R43_17225 67e12d4d6a8c0b4c07ddde745c575095 263 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4R43_08060 2df0d67d66e959124ab5845e69a23445 149 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 87 146 5.3E-22 T 14-10-2018 A4R43_08060 2df0d67d66e959124ab5845e69a23445 149 SUPERFAMILY SSF141694 2 81 3.14E-15 T 14-10-2018 A4R43_08060 2df0d67d66e959124ab5845e69a23445 149 Gene3D G3DSA:2.40.30.100 1 81 2.5E-9 T 14-10-2018 IPR037079 AF2212/PG0164-like superfamily A4R43_08060 2df0d67d66e959124ab5845e69a23445 149 Pfam PF08922 Domain of unknown function (DUF1905) 3 79 1.6E-17 T 14-10-2018 IPR015018 Protein of unknown function DUF1905 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 Gene3D G3DSA:2.40.40.20 2 90 3.0E-10 T 14-10-2018 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 7 90 2.6E-15 T 14-10-2018 IPR003338 CDC48, N-terminal subdomain A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 SMART SM01073 7 91 6.9E-22 T 14-10-2018 IPR003338 CDC48, N-terminal subdomain A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 Gene3D G3DSA:3.40.50.300 494 751 4.7E-88 T 14-10-2018 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 Gene3D G3DSA:3.40.50.300 226 403 8.8E-24 T 14-10-2018 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 277 398 2.1E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 533 663 1.1E-38 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 SUPERFAMILY SSF50692 6 89 2.1E-12 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 ProSitePatterns PS00674 AAA-protein family signature. 634 652 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 SUPERFAMILY SSF52540 240 466 3.15E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 Gene3D G3DSA:1.10.8.60 665 737 4.7E-88 T 14-10-2018 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 SMART SM01072 108 192 1.6E-4 T 14-10-2018 IPR004201 CDC48, domain 2 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 SMART SM00382 529 666 2.6E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 SMART SM00382 273 404 8.8E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 Gene3D G3DSA:1.10.8.60 404 488 1.3E-16 T 14-10-2018 A4R43_26110 86236d50f7ca692dbe0d31543c4d2224 758 SUPERFAMILY SSF52540 494 750 8.34E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 Gene3D G3DSA:1.10.560.10 7 519 6.5E-222 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 SUPERFAMILY SSF52029 184 374 1.36E-82 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 SUPERFAMILY SSF48592 6 519 5.41E-72 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 SUPERFAMILY SSF54849 137 201 2.75E-25 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 3.0E-94 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 PRINTS PR00298 60kDa chaperonin signature 348 373 2.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 PRINTS PR00298 60kDa chaperonin signature 266 289 2.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 PRINTS PR00298 60kDa chaperonin signature 82 109 2.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 PRINTS PR00298 60kDa chaperonin signature 26 52 2.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 PRINTS PR00298 60kDa chaperonin signature 396 417 2.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 Gene3D G3DSA:3.30.260.10 135 408 6.5E-222 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.179 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 Gene3D G3DSA:3.50.7.10 190 370 6.5E-222 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_26070 97e46ed57f58ce04c3dc8d4e7f9cd5f5 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 4.1E-248 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4R43_33775 a4191b8dec2c9b749bed27ef807f8d5a 381 Pfam PF07994 Myo-inositol-1-phosphate synthase 3 377 5.3E-43 T 14-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A4R43_33775 a4191b8dec2c9b749bed27ef807f8d5a 381 Pfam PF01658 Myo-inositol-1-phosphate synthase 219 323 2.1E-23 T 14-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A4R43_33775 a4191b8dec2c9b749bed27ef807f8d5a 381 PIRSF PIRSF015578 1 381 2.1E-78 T 14-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A4R43_33775 a4191b8dec2c9b749bed27ef807f8d5a 381 Gene3D G3DSA:3.30.360.10 219 319 5.5E-123 T 14-10-2018 A4R43_33775 a4191b8dec2c9b749bed27ef807f8d5a 381 SUPERFAMILY SSF55347 218 322 3.14E-26 T 14-10-2018 A4R43_33775 a4191b8dec2c9b749bed27ef807f8d5a 381 SUPERFAMILY SSF51735 4 378 1.97E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_33775 a4191b8dec2c9b749bed27ef807f8d5a 381 Gene3D G3DSA:3.40.50.720 6 370 5.5E-123 T 14-10-2018 A4R43_00045 cdcade9f1dcdc26b4d281f4c3c93f5bf 298 Pfam PF00665 Integrase core domain 99 249 5.1E-44 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_00045 cdcade9f1dcdc26b4d281f4c3c93f5bf 298 Pfam PF13565 Homeodomain-like domain 8 75 3.2E-10 T 14-10-2018 A4R43_00045 cdcade9f1dcdc26b4d281f4c3c93f5bf 298 SUPERFAMILY SSF53098 101 292 2.78E-37 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_00045 cdcade9f1dcdc26b4d281f4c3c93f5bf 298 Gene3D G3DSA:3.30.420.10 128 293 2.5E-29 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_11915 cf8772179bea81138c18a270c1b23da0 203 Gene3D G3DSA:1.10.357.10 59 198 3.3E-31 T 14-10-2018 A4R43_11915 cf8772179bea81138c18a270c1b23da0 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 7.7E-20 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11915 cf8772179bea81138c18a270c1b23da0 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_11915 cf8772179bea81138c18a270c1b23da0 203 SUPERFAMILY SSF48498 88 197 2.1E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11915 cf8772179bea81138c18a270c1b23da0 203 Gene3D G3DSA:1.10.10.60 14 58 7.8E-21 T 14-10-2018 A4R43_11915 cf8772179bea81138c18a270c1b23da0 203 SUPERFAMILY SSF46689 11 90 1.65E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11915 cf8772179bea81138c18a270c1b23da0 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.9E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11915 cf8772179bea81138c18a270c1b23da0 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.9E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 Pfam PF09269 Domain of unknown function (DUF1967) 362 432 5.4E-26 T 14-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 Gene3D G3DSA:2.40.240.60 360 435 1.0E-21 T 14-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily A4R43_39265 e35ada67f2e822afcda045e13a029821 481 SUPERFAMILY SSF102741 362 434 3.27E-21 T 14-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily A4R43_39265 e35ada67f2e822afcda045e13a029821 481 SUPERFAMILY SSF52540 162 342 5.48E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39265 e35ada67f2e822afcda045e13a029821 481 Gene3D G3DSA:3.40.50.300 161 351 1.2E-48 T 14-10-2018 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 5 333 4.2E-124 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 SUPERFAMILY SSF82051 5 158 7.59E-47 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily A4R43_39265 e35ada67f2e822afcda045e13a029821 481 Pfam PF01018 GTP1/OBG 6 158 8.7E-51 T 14-10-2018 IPR006169 GTP1/OBG domain A4R43_39265 e35ada67f2e822afcda045e13a029821 481 Hamap MF_01454 GTPase Obg [obg]. 4 336 44.238 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 184 202 6.2E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 6.2E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 163 183 6.2E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 6.2E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 368 433 5.1E-26 T 14-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A4R43_39265 e35ada67f2e822afcda045e13a029821 481 Gene3D G3DSA:2.70.210.12 2 159 8.0E-51 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily A4R43_39265 e35ada67f2e822afcda045e13a029821 481 Pfam PF01926 50S ribosome-binding GTPase 162 289 2.3E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 Gene3D G3DSA:1.10.10.60 3 56 1.6E-18 T 14-10-2018 A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 Gene3D G3DSA:1.10.357.10 57 192 9.5E-25 T 14-10-2018 A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 SUPERFAMILY SSF46689 12 67 5.49E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 2.0E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 Pfam PF16859 Bacterial transcriptional repressor C-terminal 74 183 8.2E-26 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_23530 c62d771b92e850f6cc433c3fd062dabf 194 SUPERFAMILY SSF48498 75 191 1.37E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 Pfam PF02803 Thiolase, C-terminal domain 275 394 9.4E-42 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 Gene3D G3DSA:3.40.47.10 130 393 1.5E-143 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 394 1.1E-136 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 Pfam PF00108 Thiolase, N-terminal domain 9 266 1.2E-97 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 SUPERFAMILY SSF53901 9 274 3.26E-86 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 Gene3D G3DSA:3.40.47.10 9 280 1.5E-143 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 ProSitePatterns PS00099 Thiolases active site. 378 391 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 PIRSF PIRSF000429 4 398 1.2E-119 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 ProSitePatterns PS00737 Thiolases signature 2. 343 359 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A4R43_20555 2a9cbf40667878b83fd7c8b76782422a 399 SUPERFAMILY SSF53901 275 394 4.43E-36 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_11200 cd3c5f393b3ac8ae1a2e92c3383090bc 349 SUPERFAMILY SSF54631 213 344 1.12E-21 T 14-10-2018 A4R43_11200 cd3c5f393b3ac8ae1a2e92c3383090bc 349 Gene3D G3DSA:3.10.580.10 201 346 8.9E-26 T 14-10-2018 A4R43_11200 cd3c5f393b3ac8ae1a2e92c3383090bc 349 Pfam PF01595 Domain of unknown function DUF21 11 204 3.0E-43 T 14-10-2018 IPR002550 CNNM, transmembrane domain A4R43_11200 cd3c5f393b3ac8ae1a2e92c3383090bc 349 Pfam PF00571 CBS domain 221 275 1.2E-6 T 14-10-2018 IPR000644 CBS domain A4R43_11200 cd3c5f393b3ac8ae1a2e92c3383090bc 349 SMART SM00116 228 276 0.0082 T 14-10-2018 IPR000644 CBS domain A4R43_02715 ac49a66b78213485c7893891e8f25e1e 436 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 27 403 2.4E-100 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4R43_02715 ac49a66b78213485c7893891e8f25e1e 436 Pfam PF06965 Na+/H+ antiporter 1 25 404 5.3E-135 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4R43_02715 ac49a66b78213485c7893891e8f25e1e 436 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 23 413 20.82 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4R43_02715 ac49a66b78213485c7893891e8f25e1e 436 Gene3D G3DSA:1.20.1530.10 20 412 8.3E-142 T 14-10-2018 IPR023171 Na/H antiporter domain superfamily A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 SUPERFAMILY SSF46894 266 329 9.52E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 Gene3D G3DSA:1.10.10.10 190 333 2.4E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 SUPERFAMILY SSF55781 92 162 1.23E-5 T 14-10-2018 A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 SMART SM00421 274 331 4.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 291 307 6.6E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 277 291 6.6E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 307 319 6.6E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 Pfam PF00196 Bacterial regulatory proteins, luxR family 278 328 2.9E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07015 e5f0f9dba40f1b74567698245488ca84 333 ProSitePatterns PS00622 LuxR-type HTH domain signature. 291 318 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30765 22a90a9136a4b6155c65e613efbe890e 166 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 128 7.9E-34 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4R43_30765 22a90a9136a4b6155c65e613efbe890e 166 Pfam PF00436 Single-strand binding protein family 7 106 3.4E-30 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A4R43_30765 22a90a9136a4b6155c65e613efbe890e 166 SUPERFAMILY SSF50249 6 166 2.94E-47 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_30765 22a90a9136a4b6155c65e613efbe890e 166 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 31.453 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4R43_30765 22a90a9136a4b6155c65e613efbe890e 166 Gene3D G3DSA:2.40.50.140 1 120 6.7E-43 T 14-10-2018 A4R43_31945 88d15321b6aab197f3bd7863d310ff70 202 Pfam PF04892 VanZ like family 95 168 5.6E-16 T 14-10-2018 IPR006976 VanZ-like A4R43_09315 038b42c3af3e17a29dbb64f748a4de56 319 Gene3D G3DSA:1.10.600.10 1 312 3.4E-90 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_09315 038b42c3af3e17a29dbb64f748a4de56 319 SUPERFAMILY SSF48576 4 298 5.47E-60 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_15190 e9254a022c53820429a583dfd16156d4 242 SUPERFAMILY SSF51735 1 229 2.37E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15190 e9254a022c53820429a583dfd16156d4 242 Pfam PF00106 short chain dehydrogenase 7 189 3.0E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15190 e9254a022c53820429a583dfd16156d4 242 Gene3D G3DSA:3.40.50.720 2 239 2.1E-27 T 14-10-2018 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SMART SM00825 Beta-ketoacyl synthase 104 526 2.8E-202 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 477 568 8.4E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Gene3D G3DSA:3.40.50.720 1257 1714 4.6E-82 T 14-10-2018 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1466 1642 9.4E-10 T 14-10-2018 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Pfam PF00550 Phosphopantetheine attachment site 1748 1812 6.4E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Pfam PF00550 Phosphopantetheine attachment site 13 78 2.5E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Gene3D G3DSA:3.30.70.3290 545 975 1.3E-125 T 14-10-2018 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SUPERFAMILY SSF51735 1466 1657 1.91E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1771 1786 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SUPERFAMILY SSF55048 754 821 1.44E-9 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Pfam PF08659 KR domain 1466 1640 2.5E-32 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SUPERFAMILY SSF53901 100 523 2.4E-96 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SUPERFAMILY SSF47336 7 117 3.4E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SUPERFAMILY SSF51735 1269 1453 4.11E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Pfam PF00698 Acyl transferase domain 630 941 2.4E-81 T 14-10-2018 IPR014043 Acyl transferase A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 356 474 9.5E-40 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 632 930 7.3E-87 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Gene3D G3DSA:3.10.129.110 989 1256 2.4E-47 T 14-10-2018 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SMART SM01294 1746 1812 5.7E-5 T 14-10-2018 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SMART SM00823 Phosphopantetheine attachment site 11 82 1.7E-6 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SMART SM00823 Phosphopantetheine attachment site 1745 1816 1.3E-11 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Gene3D G3DSA:3.40.47.10 95 543 6.1E-185 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SUPERFAMILY SSF47336 1740 1815 5.76E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SUPERFAMILY SSF52151 630 917 1.18E-61 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Gene3D G3DSA:1.10.1200.10 1726 1821 1.5E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Gene3D G3DSA:1.10.1200.10 1 82 1.7E-20 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 102 348 2.9E-86 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 SMART SM00826 990 1152 7.2E-33 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Pfam PF14765 Polyketide synthase dehydratase 990 1261 5.7E-41 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12625 9edd2e7741b33a7ebb0ff1c586306639 1830 Gene3D G3DSA:3.40.366.10 630 933 1.3E-125 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_05105 ec45f5c44af5df52f1fbc1498d52efae 375 Gene3D G3DSA:3.50.50.60 1 74 4.0E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_05105 ec45f5c44af5df52f1fbc1498d52efae 375 Pfam PF05834 Lycopene cyclase protein 2 370 1.9E-58 T 14-10-2018 A4R43_05105 ec45f5c44af5df52f1fbc1498d52efae 375 Gene3D G3DSA:3.50.50.60 80 329 1.7E-5 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_05105 ec45f5c44af5df52f1fbc1498d52efae 375 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 3.5E-7 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_05105 ec45f5c44af5df52f1fbc1498d52efae 375 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 300 3.5E-7 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_05105 ec45f5c44af5df52f1fbc1498d52efae 375 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 132 3.5E-7 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_05105 ec45f5c44af5df52f1fbc1498d52efae 375 TIGRFAM TIGR01790 carotene-cycl: lycopene cyclase family protein 2 372 4.3E-67 T 14-10-2018 IPR010108 Lycopene cyclase, beta/epsilon GO:0016117|GO:0016705 A4R43_05105 ec45f5c44af5df52f1fbc1498d52efae 375 SUPERFAMILY SSF51905 1 305 1.45E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 Gene3D G3DSA:1.10.287.130 194 267 4.6E-8 T 14-10-2018 A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 410 2.3E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 SUPERFAMILY SSF55874 258 410 2.89E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 Gene3D G3DSA:3.30.565.10 273 412 2.5E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 SMART SM00387 308 412 1.1E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 Pfam PF00512 His Kinase A (phospho-acceptor) domain 207 268 3.0E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 SUPERFAMILY SSF47384 195 267 3.73E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 409 3.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 3.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 3.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_37500 163df57ea53440beaaabb67e3c9f49bf 413 SMART SM00388 205 268 2.5E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_19635 134c48f4854ccb6b49f92ecae8f3db62 129 SUPERFAMILY SSF52091 5 97 2.55E-13 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_19635 134c48f4854ccb6b49f92ecae8f3db62 129 Pfam PF13466 STAS domain 6 82 5.6E-10 T 14-10-2018 IPR002645 STAS domain A4R43_19635 134c48f4854ccb6b49f92ecae8f3db62 129 Gene3D G3DSA:3.30.750.24 1 102 9.6E-19 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 SUPERFAMILY SSF57716 221 268 1.37E-13 T 14-10-2018 A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 207 3.6E-18 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 Gene3D G3DSA:1.10.8.50 124 268 3.9E-40 T 14-10-2018 A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 Gene3D G3DSA:3.20.190.10 2 123 1.6E-8 T 14-10-2018 IPR035937 MutM-like, N-terminal A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 SMART SM00898 2 108 3.8E-16 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 SUPERFAMILY SSF46946 121 206 4.71E-23 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 SMART SM01232 122 214 5.7E-31 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 Pfam PF06827 Zinc finger found in FPG and IleRS 240 268 3.6E-7 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A4R43_38915 f365258c8b9198f55403613c2bad3ed8 269 SUPERFAMILY SSF81624 2 123 2.49E-20 T 14-10-2018 IPR035937 MutM-like, N-terminal A4R43_39610 4a6886500165dc682fc926fe6661006f 505 Gene3D G3DSA:1.10.4160.10 14 453 1.9E-129 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily A4R43_39610 4a6886500165dc682fc926fe6661006f 505 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 22 445 3.3E-125 T 14-10-2018 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0016020|GO:0022857|GO:0055085 A4R43_39610 4a6886500165dc682fc926fe6661006f 505 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 27 476 3.5E-133 T 14-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 Pfam PF00106 short chain dehydrogenase 7 42 5.5E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 SUPERFAMILY SSF51735 6 222 1.09E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 152 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 171 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 205 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 63 74 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 114 122 9.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 63 74 9.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 152 9.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 Gene3D G3DSA:3.40.50.720 2 223 2.7E-51 T 14-10-2018 A4R43_04085 64c0f03e9f01d3f7ac146ddc25db29ea 223 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 63 221 9.6E-32 T 14-10-2018 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 Gene3D G3DSA:3.40.1160.10 1 248 4.5E-90 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 SUPERFAMILY SSF55021 331 409 9.92E-22 T 14-10-2018 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 PIRSF PIRSF000726 1 62 3.6E-21 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 PIRSF PIRSF000726 59 414 4.7E-127 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 Pfam PF01842 ACT domain 269 329 3.9E-9 T 14-10-2018 IPR002912 ACT domain A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 407 4.3E-121 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 Pfam PF00696 Amino acid kinase family 3 231 4.8E-54 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 1.9E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 PRINTS PR00474 Glutamate 5-kinase family signature 205 225 1.9E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 PRINTS PR00474 Glutamate 5-kinase family signature 153 180 1.9E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 Pfam PF13840 ACT domain 341 403 7.5E-13 T 14-10-2018 IPR027795 CASTOR, ACT domain A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 SUPERFAMILY SSF53633 4 243 2.88E-71 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 406 6.0E-115 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 Gene3D G3DSA:3.30.2130.10 249 421 3.5E-64 T 14-10-2018 A4R43_27335 cb522fdb391597b6e30bed3b108d1381 421 SUPERFAMILY SSF55021 251 331 6.3E-18 T 14-10-2018 A4R43_41680 72fbbc5ee5b59dcac409b8d458ee6bee 331 SUPERFAMILY SSF53807 50 326 1.45E-42 T 14-10-2018 A4R43_41680 72fbbc5ee5b59dcac409b8d458ee6bee 331 Gene3D G3DSA:3.40.50.1980 30 153 3.0E-18 T 14-10-2018 A4R43_41680 72fbbc5ee5b59dcac409b8d458ee6bee 331 Pfam PF01497 Periplasmic binding protein 54 301 5.8E-21 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_41680 72fbbc5ee5b59dcac409b8d458ee6bee 331 Gene3D G3DSA:3.40.50.1980 157 330 8.7E-55 T 14-10-2018 A4R43_04745 bbdd4aac0a71e9b189aca2c05076116a 105 PIRSF PIRSF002134 40 104 1.8E-4 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_04745 bbdd4aac0a71e9b189aca2c05076116a 105 SUPERFAMILY SSF46946 54 103 2.44E-6 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4R43_04745 bbdd4aac0a71e9b189aca2c05076116a 105 Gene3D G3DSA:1.10.8.50 1 105 5.9E-43 T 14-10-2018 A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 Gene3D G3DSA:3.10.450.50 169 286 1.6E-5 T 14-10-2018 A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 SUPERFAMILY SSF88659 84 164 1.14E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 SUPERFAMILY SSF88946 12 92 1.77E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 Pfam PF08281 Sigma-70, region 4 109 159 2.7E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 Pfam PF04542 Sigma-70 region 2 12 78 1.7E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 SUPERFAMILY SSF54427 172 282 2.77E-12 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 162 6.9E-14 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 Gene3D G3DSA:1.10.10.10 103 166 4.0E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03330 8755f75dad4a71bcd5a12d15d1ea1c44 293 Gene3D G3DSA:1.10.1740.10 8 78 9.4E-8 T 14-10-2018 A4R43_04460 04fac4ea0ea156bf3a80f12bc10a9235 496 SUPERFAMILY SSF51294 73 220 1.57E-19 T 14-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_04460 04fac4ea0ea156bf3a80f12bc10a9235 496 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 202 221 7.7E-4 T 14-10-2018 IPR030934 Intein C-terminal splicing region A4R43_04460 04fac4ea0ea156bf3a80f12bc10a9235 496 SMART SM00306 71 214 2.7E-11 T 14-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_04460 04fac4ea0ea156bf3a80f12bc10a9235 496 SMART SM00305 182 226 9.8E-5 T 14-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_04460 04fac4ea0ea156bf3a80f12bc10a9235 496 Gene3D G3DSA:2.170.16.10 66 228 2.9E-21 T 14-10-2018 A4R43_04460 04fac4ea0ea156bf3a80f12bc10a9235 496 Gene3D G3DSA:3.80.30.30 320 463 2.2E-5 T 14-10-2018 A4R43_04460 04fac4ea0ea156bf3a80f12bc10a9235 496 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 73 147 1.8E-6 T 14-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_04460 04fac4ea0ea156bf3a80f12bc10a9235 496 SUPERFAMILY SSF102114 285 419 7.46E-7 T 14-10-2018 A4R43_00370 722330ff02f8877bc445a1ede54e4427 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 1.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00370 722330ff02f8877bc445a1ede54e4427 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 1.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00370 722330ff02f8877bc445a1ede54e4427 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 1.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00370 722330ff02f8877bc445a1ede54e4427 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00370 722330ff02f8877bc445a1ede54e4427 139 SUPERFAMILY SSF46785 10 137 3.81E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00370 722330ff02f8877bc445a1ede54e4427 139 Pfam PF12802 MarR family 41 90 2.6E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00370 722330ff02f8877bc445a1ede54e4427 139 SMART SM00347 27 127 5.4E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00370 722330ff02f8877bc445a1ede54e4427 139 Gene3D G3DSA:1.10.10.10 6 139 2.2E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18565 7997cc17ad5561a863e5d7d8987f7cc8 163 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 8 161 1.2E-49 T 14-10-2018 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 A4R43_18565 7997cc17ad5561a863e5d7d8987f7cc8 163 Gene3D G3DSA:1.10.3330.10 2 163 5.9E-53 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4R43_18565 7997cc17ad5561a863e5d7d8987f7cc8 163 SUPERFAMILY SSF158694 4 161 3.53E-43 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4R43_18565 7997cc17ad5561a863e5d7d8987f7cc8 163 Pfam PF09349 OHCU decarboxylase 9 158 2.9E-37 T 14-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4R43_26810 dd099bb4d19dd99bf95797641f366044 264 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_26810 dd099bb4d19dd99bf95797641f366044 264 SUPERFAMILY SSF51717 1 263 1.83E-92 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_26810 dd099bb4d19dd99bf95797641f366044 264 Gene3D G3DSA:3.20.20.20 1 264 1.4E-107 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_26810 dd099bb4d19dd99bf95797641f366044 264 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 260 4.5E-93 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A4R43_26810 dd099bb4d19dd99bf95797641f366044 264 Pfam PF00809 Pterin binding enzyme 1 246 2.1E-88 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_41815 5aad45414d3c1037cb077bbc46f8984b 373 Pfam PF13565 Homeodomain-like domain 61 142 4.1E-15 T 14-10-2018 A4R43_41815 5aad45414d3c1037cb077bbc46f8984b 373 SUPERFAMILY SSF46689 20 145 1.08E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_41815 5aad45414d3c1037cb077bbc46f8984b 373 SUPERFAMILY SSF53098 233 343 1.29E-8 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_41815 5aad45414d3c1037cb077bbc46f8984b 373 Pfam PF13358 DDE superfamily endonuclease 180 315 1.4E-13 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain A4R43_13030 374807d6df267e553fba6b689b53ad21 203 SUPERFAMILY SSF46689 9 77 7.28E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13030 374807d6df267e553fba6b689b53ad21 203 SUPERFAMILY SSF48498 85 200 4.79E-29 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_13030 374807d6df267e553fba6b689b53ad21 203 Gene3D G3DSA:1.10.357.10 59 202 8.0E-35 T 14-10-2018 A4R43_13030 374807d6df267e553fba6b689b53ad21 203 Gene3D G3DSA:1.10.10.60 13 58 8.0E-17 T 14-10-2018 A4R43_13030 374807d6df267e553fba6b689b53ad21 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 60 8.6E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 SMART SM00421 216 273 1.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 Pfam PF00196 Bacterial regulatory proteins, luxR family 219 273 3.4E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 219 233 3.9E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 233 249 3.9E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 249 261 3.9E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 SUPERFAMILY SSF46894 209 279 2.69E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 SUPERFAMILY SSF55781 7 144 4.32E-6 T 14-10-2018 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 ProSitePatterns PS00622 LuxR-type HTH domain signature. 233 260 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 Gene3D G3DSA:1.10.10.10 212 279 3.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05655 59c88ee00101ad28916d5d121f86185b 279 Gene3D G3DSA:3.30.450.40 6 133 9.2E-18 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_02785 4d9da8f81e95f71922794ed2049998ba 247 Gene3D G3DSA:1.10.10.60 153 232 1.5E-10 T 14-10-2018 A4R43_02785 4d9da8f81e95f71922794ed2049998ba 247 Pfam PF12833 Helix-turn-helix domain 157 228 1.2E-9 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_02785 4d9da8f81e95f71922794ed2049998ba 247 SMART SM00342 153 227 1.7E-4 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_14810 0dd85fe538359a8f054aac90aed5fb41 225 Gene3D G3DSA:3.40.50.300 2 185 4.2E-10 T 14-10-2018 A4R43_14810 0dd85fe538359a8f054aac90aed5fb41 225 SUPERFAMILY SSF52540 9 183 2.26E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10370 fee48b5e0a79e8da43528818b945d1f4 465 Gene3D G3DSA:3.40.309.10 224 409 2.9E-170 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_10370 fee48b5e0a79e8da43528818b945d1f4 465 Gene3D G3DSA:3.40.605.10 5 462 2.9E-170 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_10370 fee48b5e0a79e8da43528818b945d1f4 465 Pfam PF00171 Aldehyde dehydrogenase family 5 428 1.1E-35 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_10370 fee48b5e0a79e8da43528818b945d1f4 465 SUPERFAMILY SSF53720 4 456 5.24E-75 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_21450 513130bbd88dfd8f29df7ecd736ca6bf 240 SMART SM01012 151 229 3.9E-7 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_21450 513130bbd88dfd8f29df7ecd736ca6bf 240 Gene3D G3DSA:3.30.450.40 23 162 1.2E-12 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_21450 513130bbd88dfd8f29df7ecd736ca6bf 240 Pfam PF03861 ANTAR domain 186 229 1.3E-6 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_21450 513130bbd88dfd8f29df7ecd736ca6bf 240 SUPERFAMILY SSF55781 25 161 6.17E-14 T 14-10-2018 A4R43_04835 7350bafd96528840ee2e03a81e5a5953 259 Gene3D G3DSA:3.60.10.10 1 258 7.0E-70 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_04835 7350bafd96528840ee2e03a81e5a5953 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 257 5.1E-78 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A4R43_04835 7350bafd96528840ee2e03a81e5a5953 259 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A4R43_04835 7350bafd96528840ee2e03a81e5a5953 259 SUPERFAMILY SSF56219 1 258 3.01E-71 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_04835 7350bafd96528840ee2e03a81e5a5953 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 1.8E-62 T 14-10-2018 A4R43_04835 7350bafd96528840ee2e03a81e5a5953 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 3.8E-21 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4R43_08010 5bc776c8173e642df0125efe101040be 692 PIRSF PIRSF038927 1 691 0.0 T 14-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A4R43_08010 5bc776c8173e642df0125efe101040be 692 Pfam PF00199 Catalase 26 410 7.1E-175 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 356 364 - T 14-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 Gene3D G3DSA:3.40.50.880 532 691 2.1E-39 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_08010 5bc776c8173e642df0125efe101040be 692 SUPERFAMILY SSF52317 535 671 5.0E-18 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_08010 5bc776c8173e642df0125efe101040be 692 Gene3D G3DSA:2.40.180.10 1 434 7.2E-205 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A4R43_08010 5bc776c8173e642df0125efe101040be 692 Pfam PF06628 Catalase-related immune-responsive 440 503 5.1E-23 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 Gene3D G3DSA:1.20.1370.20 435 531 3.8E-35 T 14-10-2018 A4R43_08010 5bc776c8173e642df0125efe101040be 692 SUPERFAMILY SSF56634 5 530 3.14E-216 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 ProSitePatterns PS00438 Catalase proximal active site signature. 62 78 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 Pfam PF01965 DJ-1/PfpI family 536 648 1.5E-10 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_08010 5bc776c8173e642df0125efe101040be 692 SMART SM01060 26 414 2.8E-268 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 PRINTS PR00067 Catalase signature 123 140 7.5E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 PRINTS PR00067 Catalase signature 343 369 7.5E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 PRINTS PR00067 Catalase signature 102 120 7.5E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 PRINTS PR00067 Catalase signature 142 160 7.5E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 PRINTS PR00067 Catalase signature 311 338 7.5E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_08010 5bc776c8173e642df0125efe101040be 692 PRINTS PR00067 Catalase signature 39 62 7.5E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_37260 90b6f54e3acab1a6e5c1c5c1edc94726 527 Gene3D G3DSA:1.10.275.10 2 196 2.2E-65 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal A4R43_37260 90b6f54e3acab1a6e5c1c5c1edc94726 527 SUPERFAMILY SSF48557 3 519 1.18E-170 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4R43_37260 90b6f54e3acab1a6e5c1c5c1edc94726 527 Pfam PF00221 Aromatic amino acid lyase 10 488 4.7E-162 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A4R43_37260 90b6f54e3acab1a6e5c1c5c1edc94726 527 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 138 153 - T 14-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 A4R43_37260 90b6f54e3acab1a6e5c1c5c1edc94726 527 Gene3D G3DSA:1.20.200.10 197 527 4.6E-127 T 14-10-2018 A4R43_37260 90b6f54e3acab1a6e5c1c5c1edc94726 527 TIGRFAM TIGR03832 Tyr_2_3_mutase: tyrosine 2,3-aminomutase 5 509 6.2E-275 T 14-10-2018 IPR022314 Tyrosine 2,3-aminomutase, putative KEGG: 00350+5.4.3.6+4.3.1.23 A4R43_29810 7060d026dcb94637922fad84e4d0a5b6 394 Pfam PF00296 Luciferase-like monooxygenase 35 304 1.0E-25 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_29810 7060d026dcb94637922fad84e4d0a5b6 394 Gene3D G3DSA:3.20.20.30 20 393 4.3E-72 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_29810 7060d026dcb94637922fad84e4d0a5b6 394 SUPERFAMILY SSF51679 26 391 7.59E-52 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 538 1.2E-43 T 14-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 SMART SM00487 178 353 1.9E-23 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 3.4E-14 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 Gene3D G3DSA:3.40.50.300 354 546 2.8E-46 T 14-10-2018 A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 Pfam PF13625 Helicase conserved C-terminal domain 6 133 2.1E-45 T 14-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 SUPERFAMILY SSF52540 138 345 1.93E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 Gene3D G3DSA:3.40.50.300 174 353 1.1E-37 T 14-10-2018 A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 SMART SM00490 420 500 7.0E-11 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_26025 7b3d98cdf652894b95a7c1fd8ba8ca83 548 SUPERFAMILY SSF52540 290 511 1.92E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05535 75667ca8deaadde48a18c2d850066895 344 Pfam PF13377 Periplasmic binding protein-like domain 168 335 2.7E-34 T 14-10-2018 A4R43_05535 75667ca8deaadde48a18c2d850066895 344 Gene3D G3DSA:3.40.50.2300 160 290 1.1E-75 T 14-10-2018 A4R43_05535 75667ca8deaadde48a18c2d850066895 344 SUPERFAMILY SSF53822 60 336 2.17E-70 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_05535 75667ca8deaadde48a18c2d850066895 344 SMART SM00354 1 71 5.9E-24 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_05535 75667ca8deaadde48a18c2d850066895 344 SUPERFAMILY SSF47413 1 59 1.03E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_05535 75667ca8deaadde48a18c2d850066895 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 14-10-2018 A4R43_05535 75667ca8deaadde48a18c2d850066895 344 Gene3D G3DSA:3.40.50.2300 56 306 1.1E-75 T 14-10-2018 A4R43_05535 75667ca8deaadde48a18c2d850066895 344 Gene3D G3DSA:1.10.260.40 1 55 1.0E-19 T 14-10-2018 A4R43_05535 75667ca8deaadde48a18c2d850066895 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 47 3.1E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_36285 29b73db7aa7c39a3918b8388a7abba1f 692 SUPERFAMILY SSF52540 47 650 1.36E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_36285 29b73db7aa7c39a3918b8388a7abba1f 692 Gene3D G3DSA:3.40.50.300 496 683 7.7E-30 T 14-10-2018 A4R43_36285 29b73db7aa7c39a3918b8388a7abba1f 692 Pfam PF13307 Helicase C-terminal domain 509 669 1.7E-27 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A4R43_36285 29b73db7aa7c39a3918b8388a7abba1f 692 SMART SM00491 527 656 3.0E-42 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A4R43_36285 29b73db7aa7c39a3918b8388a7abba1f 692 Pfam PF00270 DEAD/DEAH box helicase 47 99 6.0E-6 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_36285 29b73db7aa7c39a3918b8388a7abba1f 692 SMART SM00487 29 316 2.0E-6 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_36285 29b73db7aa7c39a3918b8388a7abba1f 692 Gene3D G3DSA:3.40.50.300 32 293 3.7E-46 T 14-10-2018 A4R43_12020 d7d4102e659b28d55ddfd1b0d0bdf203 188 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 64 106 1.2E-12 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_12020 d7d4102e659b28d55ddfd1b0d0bdf203 188 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 6 182 6.3E-58 T 14-10-2018 IPR010195 Uncharacterised peroxidase-related A4R43_12020 d7d4102e659b28d55ddfd1b0d0bdf203 188 Gene3D G3DSA:1.20.1290.10 65 188 1.2E-37 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_12020 d7d4102e659b28d55ddfd1b0d0bdf203 188 SUPERFAMILY SSF69118 5 187 1.13E-53 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_12020 d7d4102e659b28d55ddfd1b0d0bdf203 188 Pfam PF02627 Carboxymuconolactone decarboxylase family 45 102 6.4E-13 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_12020 d7d4102e659b28d55ddfd1b0d0bdf203 188 Gene3D G3DSA:1.20.5.810 13 64 3.1E-21 T 14-10-2018 A4R43_14095 c3ccd00843b2d990dd50a3079c58ce98 118 Gene3D G3DSA:1.10.10.10 1 113 2.8E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14095 c3ccd00843b2d990dd50a3079c58ce98 118 SUPERFAMILY SSF46785 3 109 1.07E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14095 c3ccd00843b2d990dd50a3079c58ce98 118 Pfam PF01638 HxlR-like helix-turn-helix 15 102 1.8E-26 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 SMART SM00421 155 212 3.1E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 SUPERFAMILY SSF46894 148 218 1.46E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 Gene3D G3DSA:3.40.50.12740 5 218 4.5E-68 T 14-10-2018 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 SMART SM00448 5 120 7.5E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 Pfam PF00072 Response regulator receiver domain 7 120 1.0E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 SUPERFAMILY SSF52172 3 131 1.57E-30 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 4.5E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_04245 be9fc615fc61a78830c7d71d4608e3a6 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_04490 f73e00e4c3b709e56126387f0daf392b 371 Pfam PF01494 FAD binding domain 135 317 4.8E-9 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_04490 f73e00e4c3b709e56126387f0daf392b 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 131 146 3.1E-6 T 14-10-2018 A4R43_04490 f73e00e4c3b709e56126387f0daf392b 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 256 271 3.1E-6 T 14-10-2018 A4R43_04490 f73e00e4c3b709e56126387f0daf392b 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 3.1E-6 T 14-10-2018 A4R43_04490 f73e00e4c3b709e56126387f0daf392b 371 SUPERFAMILY SSF51905 1 329 6.26E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_04490 f73e00e4c3b709e56126387f0daf392b 371 Pfam PF13450 NAD(P)-binding Rossmann-like domain 1 35 2.1E-9 T 14-10-2018 A4R43_04490 f73e00e4c3b709e56126387f0daf392b 371 Gene3D G3DSA:3.30.9.30 31 247 1.3E-73 T 14-10-2018 A4R43_04490 f73e00e4c3b709e56126387f0daf392b 371 Gene3D G3DSA:3.50.50.60 1 320 1.3E-73 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_22720 e023407aec5db938fda709cad740d3c0 384 Gene3D G3DSA:3.50.50.60 10 367 1.2E-105 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_22720 e023407aec5db938fda709cad740d3c0 384 Gene3D G3DSA:3.30.9.10 88 313 1.2E-105 T 14-10-2018 A4R43_22720 e023407aec5db938fda709cad740d3c0 384 Pfam PF01266 FAD dependent oxidoreductase 10 353 3.5E-64 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_22720 e023407aec5db938fda709cad740d3c0 384 SUPERFAMILY SSF51905 10 372 1.34E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34395 774080d20d1452f3af11d48330d447dc 222 Pfam PF00072 Response regulator receiver domain 11 123 1.8E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 4.7E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 SMART SM00421 159 216 1.6E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 SMART SM00448 9 123 3.0E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 7.7E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 7.7E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 7.7E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 Gene3D G3DSA:3.40.50.12740 9 222 1.2E-60 T 14-10-2018 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 SUPERFAMILY SSF46894 145 221 6.12E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_34395 774080d20d1452f3af11d48330d447dc 222 SUPERFAMILY SSF52172 8 141 2.99E-28 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 659 1.7E-181 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 SUPERFAMILY SSF50677 218 395 2.09E-47 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 Gene3D G3DSA:1.10.730.10 667 841 1.3E-41 T 14-10-2018 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 861 1.3E-253 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 Pfam PF08264 Anticodon-binding domain of tRNA 710 847 1.1E-22 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 Gene3D G3DSA:3.40.50.620 24 651 1.5E-230 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 61 72 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 Gene3D G3DSA:3.90.740.10 210 421 1.5E-230 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 SUPERFAMILY SSF52374 14 658 1.18E-127 T 14-10-2018 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 415 430 4.0E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 241 264 4.0E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 544 557 4.0E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 54 65 4.0E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 4.0E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 SUPERFAMILY SSF47323 680 908 2.99E-45 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_16470 1535da4df3b5b8aeb0852ec5d1c66ddd 1054 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 12 1048 13.969 T 14-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_27465 d26b4e0b4fecd5d923b1300278b8be73 234 Pfam PF00072 Response regulator receiver domain 11 119 4.3E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27465 d26b4e0b4fecd5d923b1300278b8be73 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 1.0E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_27465 d26b4e0b4fecd5d923b1300278b8be73 234 Gene3D G3DSA:3.40.50.2300 5 134 4.8E-36 T 14-10-2018 A4R43_27465 d26b4e0b4fecd5d923b1300278b8be73 234 SMART SM00448 9 120 1.6E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27465 d26b4e0b4fecd5d923b1300278b8be73 234 SUPERFAMILY SSF52172 9 187 8.45E-41 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_27465 d26b4e0b4fecd5d923b1300278b8be73 234 Gene3D G3DSA:1.10.10.10 135 234 6.3E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27465 d26b4e0b4fecd5d923b1300278b8be73 234 SMART SM00862 156 230 4.7E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_12515 5d5978bc0167ad4c9be2f6dd8794319a 390 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_12515 5d5978bc0167ad4c9be2f6dd8794319a 390 SUPERFAMILY SSF48264 18 388 9.95E-53 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_12515 5d5978bc0167ad4c9be2f6dd8794319a 390 Pfam PF00067 Cytochrome P450 267 349 2.1E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_12515 5d5978bc0167ad4c9be2f6dd8794319a 390 Gene3D G3DSA:1.10.630.10 5 389 9.1E-78 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05015 ceab01ea9070fa946ccf4eea217ebabd 310 PRINTS PR00075 Fatty acid desaturase family 1 signature 207 228 7.5E-19 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_05015 ceab01ea9070fa946ccf4eea217ebabd 310 PRINTS PR00075 Fatty acid desaturase family 1 signature 250 264 7.5E-19 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_05015 ceab01ea9070fa946ccf4eea217ebabd 310 PRINTS PR00075 Fatty acid desaturase family 1 signature 47 69 7.5E-19 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_05015 ceab01ea9070fa946ccf4eea217ebabd 310 PRINTS PR00075 Fatty acid desaturase family 1 signature 70 90 7.5E-19 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_05015 ceab01ea9070fa946ccf4eea217ebabd 310 Pfam PF00487 Fatty acid desaturase 48 265 2.0E-20 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_24785 f2bf9996aa826ba70f7e383f4f5bfab6 481 SMART SM01329 9 340 1.7E-151 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_24785 f2bf9996aa826ba70f7e383f4f5bfab6 481 Gene3D G3DSA:3.40.718.10 1 373 7.1E-130 T 14-10-2018 A4R43_24785 f2bf9996aa826ba70f7e383f4f5bfab6 481 SUPERFAMILY SSF53659 7 344 2.69E-116 T 14-10-2018 A4R43_24785 f2bf9996aa826ba70f7e383f4f5bfab6 481 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 10 336 2.6E-94 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_24785 f2bf9996aa826ba70f7e383f4f5bfab6 481 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 231 250 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4R43_24785 f2bf9996aa826ba70f7e383f4f5bfab6 481 Gene3D G3DSA:3.30.70.1570 374 481 3.3E-30 T 14-10-2018 A4R43_24785 f2bf9996aa826ba70f7e383f4f5bfab6 481 TIGRFAM TIGR02924 ICDH_alpha: isocitrate dehydrogenase 9 475 2.7E-204 T 14-10-2018 IPR014273 Isocitrate dehydrogenase, alphaproteobacteria-type GO:0004450|GO:0006097|GO:0006099|GO:0046872|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A4R43_13825 67cc9a5071aa93470e42ebddaf142274 474 SUPERFAMILY SSF51905 4 464 1.73E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13825 67cc9a5071aa93470e42ebddaf142274 474 Gene3D G3DSA:3.90.660.20 38 414 1.2E-110 T 14-10-2018 A4R43_13825 67cc9a5071aa93470e42ebddaf142274 474 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 3 466 1.5E-46 T 14-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4R43_13825 67cc9a5071aa93470e42ebddaf142274 474 Pfam PF01593 Flavin containing amine oxidoreductase 12 463 1.5E-40 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4R43_13825 67cc9a5071aa93470e42ebddaf142274 474 SUPERFAMILY SSF54373 303 415 1.07E-22 T 14-10-2018 A4R43_13825 67cc9a5071aa93470e42ebddaf142274 474 Gene3D G3DSA:1.10.3110.10 102 195 1.2E-110 T 14-10-2018 A4R43_13825 67cc9a5071aa93470e42ebddaf142274 474 Gene3D G3DSA:3.50.50.60 6 456 1.2E-110 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 Gene3D G3DSA:3.20.190.10 1 96 1.4E-13 T 14-10-2018 IPR035937 MutM-like, N-terminal A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 SMART SM01232 135 225 5.8E-23 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 Pfam PF06827 Zinc finger found in FPG and IleRS 240 267 1.3E-6 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 SUPERFAMILY SSF81624 2 140 7.33E-22 T 14-10-2018 IPR035937 MutM-like, N-terminal A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 SMART SM00898 2 121 5.1E-19 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 Gene3D G3DSA:1.10.8.50 137 268 2.6E-31 T 14-10-2018 A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 135 217 4.4E-15 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 SUPERFAMILY SSF57716 225 268 1.03E-10 T 14-10-2018 A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 SUPERFAMILY SSF46946 134 215 2.88E-19 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4R43_28670 67cb0f45220b09b37d48113e6ae5ac34 283 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 90 4.3E-15 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4R43_04175 e2adaf1ed5c064b5c44d4b3cadd0c3cd 191 SMART SM00347 32 135 4.1E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_04175 e2adaf1ed5c064b5c44d4b3cadd0c3cd 191 Pfam PF12802 MarR family 37 98 1.8E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_04175 e2adaf1ed5c064b5c44d4b3cadd0c3cd 191 Gene3D G3DSA:1.10.10.10 6 158 2.7E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04175 e2adaf1ed5c064b5c44d4b3cadd0c3cd 191 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 2.0E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_04175 e2adaf1ed5c064b5c44d4b3cadd0c3cd 191 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.0E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_04175 e2adaf1ed5c064b5c44d4b3cadd0c3cd 191 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.0E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_04175 e2adaf1ed5c064b5c44d4b3cadd0c3cd 191 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.0E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_04175 e2adaf1ed5c064b5c44d4b3cadd0c3cd 191 SUPERFAMILY SSF46785 3 147 5.4E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00335 298efccf388c6536f857a4079ed571b3 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 8.6E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00335 298efccf388c6536f857a4079ed571b3 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 8.6E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00335 298efccf388c6536f857a4079ed571b3 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 8.6E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00335 298efccf388c6536f857a4079ed571b3 161 SMART SM00347 35 133 8.5E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00335 298efccf388c6536f857a4079ed571b3 161 SUPERFAMILY SSF46785 10 144 2.86E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00335 298efccf388c6536f857a4079ed571b3 161 Pfam PF12802 MarR family 41 96 1.8E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_00335 298efccf388c6536f857a4079ed571b3 161 Gene3D G3DSA:1.10.10.10 2 145 5.6E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39940 b23cf1efd994148c3d397159cddfca06 312 Gene3D G3DSA:3.10.180.10 3 123 6.0E-39 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_39940 b23cf1efd994148c3d397159cddfca06 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 256 2.4E-15 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_39940 b23cf1efd994148c3d397159cddfca06 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 120 2.2E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_39940 b23cf1efd994148c3d397159cddfca06 312 SUPERFAMILY SSF54593 6 290 4.61E-40 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_39940 b23cf1efd994148c3d397159cddfca06 312 Gene3D G3DSA:3.10.180.10 136 290 4.1E-41 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_32875 92631e7223b1760f72325f207eb35996 78 SUPERFAMILY SSF52833 4 77 1.28E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_32875 92631e7223b1760f72325f207eb35996 78 Pfam PF05768 Glutaredoxin-like domain (DUF836) 5 77 1.5E-13 T 14-10-2018 IPR008554 Glutaredoxin-like A4R43_32875 92631e7223b1760f72325f207eb35996 78 Gene3D G3DSA:3.40.30.10 1 78 1.9E-21 T 14-10-2018 A4R43_00680 6f62acd839d0f3c6f61ed3722ec80295 207 SUPERFAMILY SSF48498 84 190 8.4E-14 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_00680 6f62acd839d0f3c6f61ed3722ec80295 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 8.3E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00680 6f62acd839d0f3c6f61ed3722ec80295 207 SUPERFAMILY SSF46689 9 87 2.96E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00680 6f62acd839d0f3c6f61ed3722ec80295 207 Gene3D G3DSA:1.10.357.10 2 195 5.0E-41 T 14-10-2018 A4R43_00680 6f62acd839d0f3c6f61ed3722ec80295 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00680 6f62acd839d0f3c6f61ed3722ec80295 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_39740 6f3a74e74a9f55ed90f836aed8c0f049 130 SUPERFAMILY SSF46785 3 125 1.15E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39740 6f3a74e74a9f55ed90f836aed8c0f049 130 Gene3D G3DSA:1.10.10.10 2 78 1.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39740 6f3a74e74a9f55ed90f836aed8c0f049 130 Gene3D G3DSA:3.30.1490.190 79 130 1.3E-22 T 14-10-2018 A4R43_39740 6f3a74e74a9f55ed90f836aed8c0f049 130 Pfam PF01475 Ferric uptake regulator family 3 119 4.7E-34 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4R43_17590 770c430c38b27e55a93347428412b724 339 TIGRFAM TIGR00433 bioB: biotin synthase 36 330 9.4E-104 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4R43_17590 770c430c38b27e55a93347428412b724 339 SUPERFAMILY SSF102114 25 314 1.57E-64 T 14-10-2018 A4R43_17590 770c430c38b27e55a93347428412b724 339 PIRSF PIRSF001619 7 338 2.7E-102 T 14-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4R43_17590 770c430c38b27e55a93347428412b724 339 SMART SM00876 240 332 8.4E-25 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4R43_17590 770c430c38b27e55a93347428412b724 339 Gene3D G3DSA:3.20.20.70 27 334 5.4E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17590 770c430c38b27e55a93347428412b724 339 Hamap MF_01694 Biotin synthase [bioB]. 24 333 36.781 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4R43_17590 770c430c38b27e55a93347428412b724 339 Pfam PF04055 Radical SAM superfamily 71 228 1.2E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_17590 770c430c38b27e55a93347428412b724 339 SMART SM00729 64 269 2.3E-36 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_17590 770c430c38b27e55a93347428412b724 339 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 241 328 2.5E-10 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 SUPERFAMILY SSF50249 3 126 6.85E-50 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 7.2E-53 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 3.3E-124 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 4.9E-34 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 SUPERFAMILY SSF50104 127 271 9.63E-54 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 46.982 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 Gene3D G3DSA:2.40.50.140 1 115 3.8E-48 T 14-10-2018 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 PIRSF PIRSF002158 4 274 6.3E-91 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 SMART SM01382 125 253 1.2E-85 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 Gene3D G3DSA:2.30.30.30 119 196 6.7E-30 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 SMART SM01383 42 119 3.2E-42 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33855 01250a5a26df247ed2b26413dd687c48 277 Gene3D G3DSA:4.10.950.10 197 273 8.4E-30 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 SUPERFAMILY SSF46785 8 134 1.14E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 SMART SM00347 20 120 3.7E-21 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 76 2.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 2.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 2.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 44 60 2.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 Gene3D G3DSA:1.10.10.10 2 138 1.9E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 59 93 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_11975 e65765b12e90da5d3f254c740b3ca396 146 Pfam PF01047 MarR family 37 85 1.6E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_08170 54dfb97c3888df86c1c368cc7c257cd3 198 SUPERFAMILY SSF109854 16 193 5.8E-35 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_08170 54dfb97c3888df86c1c368cc7c257cd3 198 Pfam PF04978 Protein of unknown function (DUF664) 24 194 2.0E-42 T 14-10-2018 IPR007061 Protein of unknown function DUF664 A4R43_08170 54dfb97c3888df86c1c368cc7c257cd3 198 Gene3D G3DSA:1.20.120.450 3 198 2.9E-37 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_32050 69b86ddedb5dd99304f28ba0b63ca384 203 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 30 199 8.0E-46 T 14-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A4R43_32050 69b86ddedb5dd99304f28ba0b63ca384 203 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 191 2.2E-62 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A4R43_32050 69b86ddedb5dd99304f28ba0b63ca384 203 SMART SM00796 1 191 3.2E-78 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A4R43_32050 69b86ddedb5dd99304f28ba0b63ca384 203 SUPERFAMILY SSF50891 80 202 2.01E-42 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_32050 69b86ddedb5dd99304f28ba0b63ca384 203 Gene3D G3DSA:2.40.100.10 75 203 6.5E-56 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_32050 69b86ddedb5dd99304f28ba0b63ca384 203 Gene3D G3DSA:3.30.1360.40 2 74 3.3E-13 T 14-10-2018 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 SUPERFAMILY SSF46785 177 223 1.49E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 Gene3D G3DSA:1.10.10.10 1 52 7.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 Gene3D G3DSA:1.10.10.10 175 220 3.4E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 SMART SM00344 3 107 5.8E-5 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 SMART SM00344 177 278 1.3E-15 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 Gene3D G3DSA:3.30.70.920 225 318 8.8E-15 T 14-10-2018 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 SUPERFAMILY SSF46785 2 50 2.14E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.5E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.5E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.5E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 SUPERFAMILY SSF54909 233 311 2.95E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 2.1E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 Pfam PF13404 AsnC-type helix-turn-helix domain 177 214 1.9E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 Pfam PF01037 Lrp/AsnC ligand binding domain 240 309 1.8E-12 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_03155 13b81c579644ab89ffbe455e444c324e 320 ProSitePatterns PS00519 AsnC-type HTH domain signature. 191 217 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4R43_25290 c3c498e74c2a5a8e0b262f483448b44b 301 Gene3D G3DSA:3.40.50.880 2 211 4.4E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_25290 c3c498e74c2a5a8e0b262f483448b44b 301 SMART SM00342 228 300 4.7E-5 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_25290 c3c498e74c2a5a8e0b262f483448b44b 301 Pfam PF01965 DJ-1/PfpI family 3 171 1.5E-20 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_25290 c3c498e74c2a5a8e0b262f483448b44b 301 Gene3D G3DSA:1.10.10.60 212 299 8.3E-18 T 14-10-2018 A4R43_25290 c3c498e74c2a5a8e0b262f483448b44b 301 SUPERFAMILY SSF52317 3 193 1.07E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_25290 c3c498e74c2a5a8e0b262f483448b44b 301 SUPERFAMILY SSF46689 212 262 3.51E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25290 c3c498e74c2a5a8e0b262f483448b44b 301 Pfam PF12833 Helix-turn-helix domain 234 296 9.9E-13 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_28540 db3760e239196fca3f53c3fbcd48661e 208 Gene3D G3DSA:3.30.450.40 78 154 1.7E-14 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_28540 db3760e239196fca3f53c3fbcd48661e 208 SUPERFAMILY SSF46785 8 77 3.37E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_28540 db3760e239196fca3f53c3fbcd48661e 208 SUPERFAMILY SSF55781 64 207 1.7E-20 T 14-10-2018 A4R43_28540 db3760e239196fca3f53c3fbcd48661e 208 SMART SM00346 6 93 1.1E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_28540 db3760e239196fca3f53c3fbcd48661e 208 Pfam PF09339 IclR helix-turn-helix domain 8 60 5.9E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_28540 db3760e239196fca3f53c3fbcd48661e 208 Gene3D G3DSA:1.10.10.10 2 74 1.1E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 Gene3D G3DSA:3.30.420.40 235 463 8.4E-65 T 14-10-2018 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 SUPERFAMILY SSF53067 7 233 2.33E-48 T 14-10-2018 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 TIGRFAM TIGR01312 XylB: xylulokinase 9 426 1.1E-122 T 14-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 231 3.2E-44 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 335 356 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 SUPERFAMILY SSF53067 235 461 3.24E-40 T 14-10-2018 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 Gene3D G3DSA:3.30.420.40 2 233 1.3E-82 T 14-10-2018 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 PIRSF PIRSF000538 5 432 1.4E-83 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 241 423 7.0E-24 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4R43_34195 6bc8e7bc42fc8398a0e6b99102bb1035 472 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 124 136 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_13185 f368b4e2173e4f67dedd1090d231cdeb 245 Pfam PF00535 Glycosyl transferase family 2 3 106 7.7E-6 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_13185 f368b4e2173e4f67dedd1090d231cdeb 245 SUPERFAMILY SSF53448 1 215 6.47E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_13185 f368b4e2173e4f67dedd1090d231cdeb 245 Gene3D G3DSA:3.90.550.10 1 231 9.4E-14 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 SUPERFAMILY SSF52172 1 129 2.28E-34 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 197 5.0E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 SUPERFAMILY SSF46894 127 206 4.08E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 SMART SM00421 143 200 3.9E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 SMART SM00448 2 115 2.1E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 1.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 1.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 1.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 Gene3D G3DSA:3.40.50.12740 2 206 2.7E-69 T 14-10-2018 A4R43_35035 b292a8a704cde0afa4b2c6611acb6ce0 207 Pfam PF00072 Response regulator receiver domain 5 115 1.7E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SUPERFAMILY SSF52540 253 516 6.5E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Gene3D G3DSA:1.10.10.10 1 94 1.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SMART SM00862 15 91 1.7E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Gene3D G3DSA:1.25.40.10 813 905 4.6E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SUPERFAMILY SSF46894 2 91 1.25E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SUPERFAMILY SSF48452 681 886 3.89E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Pfam PF00931 NB-ARC domain 272 522 1.9E-9 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Pfam PF03704 Bacterial transcriptional activator domain 98 243 1.7E-41 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Gene3D G3DSA:1.25.40.10 97 261 7.0E-48 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Pfam PF13181 Tetratricopeptide repeat 703 727 0.065 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SMART SM01043 98 243 2.5E-46 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SMART SM00028 697 730 0.3 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SMART SM00028 855 888 22.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SMART SM00028 817 850 0.017 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SMART SM00028 735 770 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SMART SM00028 103 136 50.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SMART SM00028 777 810 5.8 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 PRINTS PR00364 Disease resistance protein signature 281 296 6.6E-8 T 14-10-2018 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 PRINTS PR00364 Disease resistance protein signature 448 462 6.6E-8 T 14-10-2018 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 PRINTS PR00364 Disease resistance protein signature 360 374 6.6E-8 T 14-10-2018 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 SUPERFAMILY SSF48452 93 262 9.11E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Gene3D G3DSA:1.25.40.10 644 812 1.5E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Pfam PF13424 Tetratricopeptide repeat 777 846 9.9E-11 T 14-10-2018 A4R43_17290 6aacb17355b8836bda319eddfc9806b1 905 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 89 1.5E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_31950 7b6e2fc3ffb7c3b482f27905897b5601 229 Gene3D G3DSA:3.40.50.12740 2 210 2.1E-32 T 14-10-2018 A4R43_31950 7b6e2fc3ffb7c3b482f27905897b5601 229 SMART SM00448 2 117 1.7E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_31950 7b6e2fc3ffb7c3b482f27905897b5601 229 SUPERFAMILY SSF52172 1 135 4.13E-36 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_31950 7b6e2fc3ffb7c3b482f27905897b5601 229 PIRSF PIRSF006171 1 229 1.8E-76 T 14-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 A4R43_31950 7b6e2fc3ffb7c3b482f27905897b5601 229 Pfam PF00072 Response regulator receiver domain 4 116 5.1E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_09655 566ce082522a9ece5fba1ae4764fe416 206 SMART SM00849 21 185 7.2E-37 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_09655 566ce082522a9ece5fba1ae4764fe416 206 Gene3D G3DSA:3.60.15.10 17 203 3.0E-48 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_09655 566ce082522a9ece5fba1ae4764fe416 206 SUPERFAMILY SSF56281 7 198 8.52E-46 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_09655 566ce082522a9ece5fba1ae4764fe416 206 Pfam PF00753 Metallo-beta-lactamase superfamily 22 177 8.6E-26 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_39585 e1c1f3b7956a2a24b2c8c607c93f8a55 275 SUPERFAMILY SSF63380 8 132 5.59E-10 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_39585 e1c1f3b7956a2a24b2c8c607c93f8a55 275 Pfam PF04954 Siderophore-interacting protein 138 252 1.5E-35 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain A4R43_39585 e1c1f3b7956a2a24b2c8c607c93f8a55 275 Gene3D G3DSA:2.40.30.10 2 131 3.7E-38 T 14-10-2018 A4R43_39585 e1c1f3b7956a2a24b2c8c607c93f8a55 275 Gene3D G3DSA:3.40.50.80 135 274 2.0E-47 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_39585 e1c1f3b7956a2a24b2c8c607c93f8a55 275 Pfam PF08021 Siderophore-interacting FAD-binding domain 17 131 1.5E-35 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting A4R43_12170 708fa2360e8ccaf74b8151f5fd7c1332 195 SUPERFAMILY SSF82607 31 109 1.96E-8 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_12170 708fa2360e8ccaf74b8151f5fd7c1332 195 Gene3D G3DSA:3.30.1310.10 17 115 2.0E-7 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_12170 708fa2360e8ccaf74b8151f5fd7c1332 195 Pfam PF02575 YbaB/EbfC DNA-binding family 30 109 2.1E-11 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_03815 a7af42b207503506f8d313ead7849ce6 429 Gene3D G3DSA:1.20.1250.20 213 427 1.3E-24 T 14-10-2018 A4R43_03815 a7af42b207503506f8d313ead7849ce6 429 Pfam PF00083 Sugar (and other) transporter 222 424 1.2E-11 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_03815 a7af42b207503506f8d313ead7849ce6 429 Pfam PF00083 Sugar (and other) transporter 71 209 6.5E-19 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_03815 a7af42b207503506f8d313ead7849ce6 429 Gene3D G3DSA:1.20.1250.20 18 212 5.2E-32 T 14-10-2018 A4R43_03815 a7af42b207503506f8d313ead7849ce6 429 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_03815 a7af42b207503506f8d313ead7849ce6 429 SUPERFAMILY SSF103473 14 423 5.36E-55 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 Gene3D G3DSA:1.20.120.530 91 221 2.7E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 Gene3D G3DSA:1.10.10.10 3 71 1.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 SMART SM00895 96 215 1.6E-18 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 SUPERFAMILY SSF48008 93 219 2.88E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 SMART SM00345 10 69 6.5E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 Pfam PF07729 FCD domain 96 214 1.5E-20 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 SUPERFAMILY SSF46785 8 79 3.17E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06790 d5db4953c67e3c26dc07040741dfc89d 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 69 1.2E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_00080 54585aac5e22ee00e235154fafcbd562 270 SUPERFAMILY SSF53335 18 236 4.95E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_00080 54585aac5e22ee00e235154fafcbd562 270 Pfam PF04672 S-adenosyl methyltransferase 8 268 2.1E-85 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_00080 54585aac5e22ee00e235154fafcbd562 270 Gene3D G3DSA:3.40.50.150 1 269 6.9E-101 T 14-10-2018 A4R43_00080 54585aac5e22ee00e235154fafcbd562 270 PIRSF PIRSF017393 2 269 1.9E-86 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_09605 0fdf911fb775ce6900ff8b5a4dfa78d8 66 Pfam PF14013 MT0933-like antitoxin protein 4 51 3.9E-16 T 14-10-2018 IPR028037 Antitoxin Rv0909/MT0933 A4R43_12430 5e6acb0d378a20a6b73496f722508fa0 279 SUPERFAMILY SSF46955 12 114 1.54E-21 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_12430 5e6acb0d378a20a6b73496f722508fa0 279 Pfam PF00376 MerR family regulatory protein 12 49 1.3E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_12430 5e6acb0d378a20a6b73496f722508fa0 279 Gene3D G3DSA:1.10.1660.10 10 118 4.4E-22 T 14-10-2018 A4R43_12430 5e6acb0d378a20a6b73496f722508fa0 279 SMART SM00422 11 80 9.0E-19 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23350 4f877de4e15bce42ffd0876a59db6e0a 600 PIRSF PIRSF002741 44 231 1.8E-7 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_23350 4f877de4e15bce42ffd0876a59db6e0a 600 PIRSF PIRSF002741 241 592 3.5E-42 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_23350 4f877de4e15bce42ffd0876a59db6e0a 600 Gene3D G3DSA:3.10.105.10 348 569 5.6E-40 T 14-10-2018 A4R43_23350 4f877de4e15bce42ffd0876a59db6e0a 600 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 114 507 1.8E-55 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_23350 4f877de4e15bce42ffd0876a59db6e0a 600 SUPERFAMILY SSF53850 59 597 4.27E-75 T 14-10-2018 A4R43_23350 4f877de4e15bce42ffd0876a59db6e0a 600 Gene3D G3DSA:3.40.190.10 39 342 2.4E-41 T 14-10-2018 A4R43_19390 8984ae9f0551bc0e33e96f32a9ea8715 266 SMART SM00882 4 224 2.5E-45 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_19390 8984ae9f0551bc0e33e96f32a9ea8715 266 Pfam PF01144 Coenzyme A transferase 6 223 1.5E-24 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_19390 8984ae9f0551bc0e33e96f32a9ea8715 266 Gene3D G3DSA:3.40.1080.10 5 263 1.7E-65 T 14-10-2018 A4R43_19390 8984ae9f0551bc0e33e96f32a9ea8715 266 SUPERFAMILY SSF100950 5 265 1.67E-76 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_19390 8984ae9f0551bc0e33e96f32a9ea8715 266 Gene3D G3DSA:3.30.30.40 118 154 1.7E-65 T 14-10-2018 A4R43_32705 b8356ed728d83fc9343944492f943f87 336 Pfam PF16884 N-terminal domain of oxidoreductase 9 114 4.9E-37 T 14-10-2018 A4R43_32705 b8356ed728d83fc9343944492f943f87 336 Gene3D G3DSA:3.90.180.10 22 333 5.5E-134 T 14-10-2018 A4R43_32705 b8356ed728d83fc9343944492f943f87 336 SUPERFAMILY SSF50129 288 335 1.37E-5 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_32705 b8356ed728d83fc9343944492f943f87 336 Gene3D G3DSA:3.40.50.720 128 305 5.5E-134 T 14-10-2018 A4R43_32705 b8356ed728d83fc9343944492f943f87 336 Pfam PF00107 Zinc-binding dehydrogenase 160 285 2.0E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_32705 b8356ed728d83fc9343944492f943f87 336 SMART SM00829 20 334 4.0E-9 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_32705 b8356ed728d83fc9343944492f943f87 336 SUPERFAMILY SSF50129 6 143 7.81E-40 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_32705 b8356ed728d83fc9343944492f943f87 336 SUPERFAMILY SSF51735 125 302 4.54E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_10560 d2086cd837dad3a69e340738cf11686a 271 Pfam PF04672 S-adenosyl methyltransferase 13 271 1.4E-92 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_10560 d2086cd837dad3a69e340738cf11686a 271 Gene3D G3DSA:3.40.50.150 3 271 1.1E-101 T 14-10-2018 A4R43_10560 d2086cd837dad3a69e340738cf11686a 271 PIRSF PIRSF017393 1 271 1.7E-98 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_10560 d2086cd837dad3a69e340738cf11686a 271 SUPERFAMILY SSF53335 18 252 1.55E-45 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_07330 7f48c77f07aff32f2beb5e98958e90e6 190 Gene3D G3DSA:1.10.357.10 2 187 3.3E-47 T 14-10-2018 A4R43_07330 7f48c77f07aff32f2beb5e98958e90e6 190 SUPERFAMILY SSF48498 81 182 6.23E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_07330 7f48c77f07aff32f2beb5e98958e90e6 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 9.7E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07330 7f48c77f07aff32f2beb5e98958e90e6 190 SUPERFAMILY SSF46689 4 81 3.44E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03175 aca18563740ee9180d0fad79ab069905 208 Pfam PF13305 WHG domain 92 177 5.4E-10 T 14-10-2018 IPR025996 WHG domain A4R43_03175 aca18563740ee9180d0fad79ab069905 208 SUPERFAMILY SSF46689 8 90 6.48E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03175 aca18563740ee9180d0fad79ab069905 208 SUPERFAMILY SSF48498 85 193 1.8E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_03175 aca18563740ee9180d0fad79ab069905 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 5.4E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03175 aca18563740ee9180d0fad79ab069905 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03175 aca18563740ee9180d0fad79ab069905 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03175 aca18563740ee9180d0fad79ab069905 208 Gene3D G3DSA:1.10.10.60 8 59 2.5E-14 T 14-10-2018 A4R43_03175 aca18563740ee9180d0fad79ab069905 208 Gene3D G3DSA:1.10.357.10 60 206 1.4E-21 T 14-10-2018 A4R43_41615 73f7fcff570df5413156d939a2814bf2 377 Pfam PF13469 Sulfotransferase family 87 335 6.8E-59 T 14-10-2018 A4R43_41615 73f7fcff570df5413156d939a2814bf2 377 SUPERFAMILY SSF52540 83 344 4.18E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41615 73f7fcff570df5413156d939a2814bf2 377 Gene3D G3DSA:3.40.50.300 1 377 1.4E-148 T 14-10-2018 A4R43_38140 2d0717d040391680700f744dac955bfa 271 Gene3D G3DSA:3.40.50.720 1 269 3.3E-71 T 14-10-2018 A4R43_38140 2d0717d040391680700f744dac955bfa 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 4.6E-4 T 14-10-2018 A4R43_38140 2d0717d040391680700f744dac955bfa 271 Pfam PF00106 short chain dehydrogenase 7 198 1.3E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_38140 2d0717d040391680700f744dac955bfa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.1E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.1E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.1E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.1E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.1E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38140 2d0717d040391680700f744dac955bfa 271 SUPERFAMILY SSF51735 2 260 7.91E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_14275 8094a501496a42e76600f6d482e59509 206 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 8 194 2.2E-55 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4R43_14275 8094a501496a42e76600f6d482e59509 206 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 8 194 31.162 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4R43_14275 8094a501496a42e76600f6d482e59509 206 SUPERFAMILY SSF50486 8 199 2.98E-61 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 A4R43_14275 8094a501496a42e76600f6d482e59509 206 Gene3D G3DSA:3.10.300.10 5 202 1.7E-62 T 14-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4R43_14275 8094a501496a42e76600f6d482e59509 206 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 14 191 4.8E-62 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 Gene3D G3DSA:3.40.50.720 1 234 6.0E-81 T 14-10-2018 A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 4.0E-7 T 14-10-2018 A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 3.1E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 3.1E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 3.1E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 3.1E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.1E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 3.1E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 2.0E-56 T 14-10-2018 A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 SUPERFAMILY SSF51735 2 230 7.94E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 2.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 2.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11045 0ec75b98c1001101fe49f3562317bc53 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 2.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 SUPERFAMILY SSF55347 108 218 1.92E-36 T 14-10-2018 A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 PIRSF PIRSF000161 1 248 3.2E-65 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 Gene3D G3DSA:3.40.50.720 5 237 1.2E-81 T 14-10-2018 A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 110 246 4.8E-30 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 45 247 2.5E-56 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 Gene3D G3DSA:3.30.360.10 108 216 1.2E-81 T 14-10-2018 A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 107 4.7E-27 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 129 146 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 SUPERFAMILY SSF51735 3 134 6.64E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_41165 a5cb5675000d02d7275ffd065fedc531 248 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 3 247 29.371 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 Pfam PF00890 FAD binding domain 7 490 2.6E-47 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 Gene3D G3DSA:3.50.50.60 3 214 3.3E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 Gene3D G3DSA:3.50.50.60 442 518 2.2E-19 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 Gene3D G3DSA:3.90.700.10 315 441 2.7E-21 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 Gene3D G3DSA:3.50.50.60 224 312 1.2E-9 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.8E-5 T 14-10-2018 A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 462 1.8E-5 T 14-10-2018 A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 SUPERFAMILY SSF56425 306 443 2.51E-14 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16050 c8df9f1f0b6d4b4fdae42a63305e57b2 529 SUPERFAMILY SSF51905 3 522 1.02E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_24645 df1bb271a748d56e96c765d3c7d2c3b7 110 Gene3D G3DSA:3.30.505.20 26 108 6.0E-25 T 14-10-2018 A4R43_24645 df1bb271a748d56e96c765d3c7d2c3b7 110 Pfam PF03413 Peptidase propeptide and YPEB domain 41 88 3.5E-5 T 14-10-2018 IPR025711 PepSY domain A4R43_26365 f8e2eb5aae595c417fc1def42ff4f588 506 Pfam PF07690 Major Facilitator Superfamily 17 408 2.0E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_26365 f8e2eb5aae595c417fc1def42ff4f588 506 SUPERFAMILY SSF103473 4 495 5.1E-67 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_26365 f8e2eb5aae595c417fc1def42ff4f588 506 Gene3D G3DSA:1.20.1250.20 267 498 5.0E-15 T 14-10-2018 A4R43_26365 f8e2eb5aae595c417fc1def42ff4f588 506 Gene3D G3DSA:1.20.1720.10 13 226 5.3E-43 T 14-10-2018 A4R43_06695 f9002cde996fab16081a763a9d5b41b4 202 SUPERFAMILY SSF52540 22 192 1.13E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06695 f9002cde996fab16081a763a9d5b41b4 202 Gene3D G3DSA:3.40.50.300 15 195 3.1E-14 T 14-10-2018 A4R43_06695 f9002cde996fab16081a763a9d5b41b4 202 Pfam PF03029 Conserved hypothetical ATP binding protein 26 192 2.3E-22 T 14-10-2018 IPR004130 GPN-loop GTPase A4R43_21060 a488030941c30d00154a7844ce436a1f 667 Gene3D G3DSA:1.25.40.10 178 347 1.0E-34 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 SUPERFAMILY SSF52540 344 589 6.48E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21060 a488030941c30d00154a7844ce436a1f 667 SMART SM00862 96 174 8.4E-16 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 PRINTS PR00364 Disease resistance protein signature 363 378 2.6E-7 T 14-10-2018 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 PRINTS PR00364 Disease resistance protein signature 522 536 2.6E-7 T 14-10-2018 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 PRINTS PR00364 Disease resistance protein signature 435 449 2.6E-7 T 14-10-2018 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 Pfam PF00486 Transcriptional regulatory protein, C terminal 98 160 4.6E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 SUPERFAMILY SSF47413 7 63 1.29E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 SMART SM00530 11 67 2.9E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 SUPERFAMILY SSF46894 85 174 1.42E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 Gene3D G3DSA:1.10.260.40 1 67 5.8E-12 T 14-10-2018 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 Pfam PF13560 Helix-turn-helix domain 8 69 8.2E-13 T 14-10-2018 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 SMART SM01043 179 323 1.5E-29 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_21060 a488030941c30d00154a7844ce436a1f 667 SUPERFAMILY SSF48452 177 339 9.86E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21060 a488030941c30d00154a7844ce436a1f 667 Gene3D G3DSA:1.10.10.10 78 177 8.2E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21060 a488030941c30d00154a7844ce436a1f 667 Pfam PF03704 Bacterial transcriptional activator domain 179 321 4.6E-29 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_10115 44596bfffeee832aafa992cf79623824 441 SUPERFAMILY SSF51604 135 410 2.0E-75 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_10115 44596bfffeee832aafa992cf79623824 441 SUPERFAMILY SSF54826 5 133 6.4E-30 T 14-10-2018 A4R43_10115 44596bfffeee832aafa992cf79623824 441 Gene3D G3DSA:3.20.20.120 135 395 1.5E-167 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_10115 44596bfffeee832aafa992cf79623824 441 Pfam PF13378 Enolase C-terminal domain-like 187 400 1.2E-34 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_10115 44596bfffeee832aafa992cf79623824 441 Gene3D G3DSA:3.30.390.10 7 409 1.5E-167 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_10115 44596bfffeee832aafa992cf79623824 441 SMART SM00922 181 281 2.4E-11 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_10115 44596bfffeee832aafa992cf79623824 441 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 40 133 3.2E-5 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 SUPERFAMILY SSF52540 436 663 1.01E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 SUPERFAMILY SSF52540 1065 1244 4.25E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 SUPERFAMILY SSF52540 759 1023 4.64E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 Pfam PF01580 FtsK/SpoIIIE family 803 1035 9.2E-44 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 Pfam PF01580 FtsK/SpoIIIE family 440 629 2.4E-30 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 SMART SM00382 1106 1269 19.0 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 SMART SM00382 471 651 0.0017 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 SMART SM00382 821 999 2.5E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 20 694 9.9E-256 T 14-10-2018 IPR023836 EccCa-like, Actinobacteria A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 Gene3D G3DSA:3.40.50.300 162 412 8.1E-14 T 14-10-2018 A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 Gene3D G3DSA:3.40.50.300 765 1073 2.7E-84 T 14-10-2018 A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 743 1310 5.4E-223 T 14-10-2018 IPR023837 EccCb-like, Actinobacteria A4R43_17505 2aed6054ccae1cf72b3a15ff22b5037d 1316 Gene3D G3DSA:3.40.50.300 1082 1313 1.2E-52 T 14-10-2018 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 SUPERFAMILY SSF52540 276 490 1.69E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14785 54219334d4eb66f85e26caff12e30015 611 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 96 6.0E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 SUPERFAMILY SSF46894 4 96 4.25E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 SUPERFAMILY SSF48452 99 266 1.07E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 Gene3D G3DSA:1.10.10.10 1 99 6.6E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14785 54219334d4eb66f85e26caff12e30015 611 SMART SM00862 17 96 3.5E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 Pfam PF00931 NB-ARC domain 290 471 1.3E-11 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 Gene3D G3DSA:3.40.50.300 272 421 1.4E-20 T 14-10-2018 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 SMART SM01043 103 248 3.9E-47 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_14785 54219334d4eb66f85e26caff12e30015 611 PRINTS PR00364 Disease resistance protein signature 378 392 5.2E-5 T 14-10-2018 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 PRINTS PR00364 Disease resistance protein signature 461 475 5.2E-5 T 14-10-2018 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 PRINTS PR00364 Disease resistance protein signature 305 320 5.2E-5 T 14-10-2018 A4R43_14785 54219334d4eb66f85e26caff12e30015 611 Pfam PF03704 Bacterial transcriptional activator domain 103 248 6.2E-41 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_14785 54219334d4eb66f85e26caff12e30015 611 Gene3D G3DSA:1.25.40.10 101 268 2.9E-45 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05345 404f65b6f2ddeea3a755f1f5dc21fd0d 342 Gene3D G3DSA:3.30.200.20 9 111 2.2E-32 T 14-10-2018 A4R43_05345 404f65b6f2ddeea3a755f1f5dc21fd0d 342 Pfam PF01636 Phosphotransferase enzyme family 33 253 1.9E-51 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_05345 404f65b6f2ddeea3a755f1f5dc21fd0d 342 Gene3D G3DSA:3.90.1200.10 118 342 2.7E-69 T 14-10-2018 A4R43_05345 404f65b6f2ddeea3a755f1f5dc21fd0d 342 SUPERFAMILY SSF56112 8 314 1.79E-60 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_05960 2e7560e589ba65c8caf2f050029991b5 458 SUPERFAMILY SSF56176 4 209 3.88E-66 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_05960 2e7560e589ba65c8caf2f050029991b5 458 SUPERFAMILY SSF55103 216 451 8.83E-61 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_05960 2e7560e589ba65c8caf2f050029991b5 458 Gene3D G3DSA:3.30.70.2740 327 409 6.9E-14 T 14-10-2018 A4R43_05960 2e7560e589ba65c8caf2f050029991b5 458 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 449 1.6E-59 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_05960 2e7560e589ba65c8caf2f050029991b5 458 Pfam PF01565 FAD binding domain 35 174 1.4E-40 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_05960 2e7560e589ba65c8caf2f050029991b5 458 Gene3D G3DSA:3.30.465.40 10 220 2.4E-71 T 14-10-2018 A4R43_05960 2e7560e589ba65c8caf2f050029991b5 458 Gene3D G3DSA:1.10.45.10 410 450 1.9E-14 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4R43_17755 78ee3999f59171875da4682659ea4fda 310 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 33 57 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_17755 78ee3999f59171875da4682659ea4fda 310 Gene3D G3DSA:3.40.1190.20 1 308 1.5E-74 T 14-10-2018 IPR029056 Ribokinase-like A4R43_17755 78ee3999f59171875da4682659ea4fda 310 Pfam PF00294 pfkB family carbohydrate kinase 18 281 6.2E-43 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_17755 78ee3999f59171875da4682659ea4fda 310 SUPERFAMILY SSF53613 9 281 7.48E-50 T 14-10-2018 IPR029056 Ribokinase-like A4R43_05940 208a49164cc0eacfe41591a207ac884b 176 Pfam PF13527 Acetyltransferase (GNAT) domain 11 127 2.9E-13 T 14-10-2018 A4R43_05940 208a49164cc0eacfe41591a207ac884b 176 SUPERFAMILY SSF55729 10 176 5.87E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_05940 208a49164cc0eacfe41591a207ac884b 176 Gene3D G3DSA:3.40.630.30 2 176 2.5E-59 T 14-10-2018 A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 21 188 1.4E-31 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 Gene3D G3DSA:3.40.1440.10 213 310 1.2E-22 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 SUPERFAMILY SSF53098 20 206 2.11E-57 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 SMART SM00479 25 193 3.5E-48 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 Gene3D G3DSA:3.30.420.10 20 193 3.2E-50 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 Pfam PF01541 GIY-YIG catalytic domain 227 302 2.3E-6 T 14-10-2018 IPR000305 GIY-YIG endonuclease A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 SMART SM00465 226 307 3.2E-13 T 14-10-2018 IPR000305 GIY-YIG endonuclease A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 Pfam PF00929 Exonuclease 27 184 6.7E-35 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A4R43_17675 53235e0c75fbb175b2a1d104ba05da4c 572 SUPERFAMILY SSF82771 226 306 2.75E-15 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A4R43_05190 a1cea2ed64b4b1176fade106ea6cb398 206 SUPERFAMILY SSF160104 3 162 3.92E-28 T 14-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A4R43_05190 a1cea2ed64b4b1176fade106ea6cb398 206 Pfam PF06314 Acetoacetate decarboxylase (ADC) 3 146 1.6E-17 T 14-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A4R43_05190 a1cea2ed64b4b1176fade106ea6cb398 206 Gene3D G3DSA:2.40.400.10 1 175 4.6E-25 T 14-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 Pfam PF00089 Trypsin 37 252 3.6E-59 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 64 79 1.3E-13 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 209 221 1.3E-13 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 120 134 1.3E-13 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 210 221 - T 14-10-2018 IPR033116 Serine proteases, trypsin family, serine active site A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 74 79 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 Gene3D G3DSA:2.40.10.10 49 251 3.5E-75 T 14-10-2018 A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 SUPERFAMILY SSF50494 26 252 3.6E-70 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 Gene3D G3DSA:2.40.10.10 37 249 3.5E-75 T 14-10-2018 A4R43_18245 a2301f7e0d2dd6d3c4c0340794977d1c 259 SMART SM00020 36 255 6.8E-74 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_23105 8bbc43732c81a8f8c0c7be01bc7ecc33 194 PIRSF PIRSF000709 2 165 3.9E-10 T 14-10-2018 A4R43_23105 8bbc43732c81a8f8c0c7be01bc7ecc33 194 SUPERFAMILY SSF53254 5 191 4.06E-47 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_23105 8bbc43732c81a8f8c0c7be01bc7ecc33 194 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 191 2.3E-47 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_23105 8bbc43732c81a8f8c0c7be01bc7ecc33 194 Gene3D G3DSA:3.40.50.1240 2 192 2.6E-54 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_23105 8bbc43732c81a8f8c0c7be01bc7ecc33 194 SMART SM00855 4 152 2.1E-21 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 214 363 8.0E-47 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 PIRSF PIRSF016578 17 362 1.9E-12 T 14-10-2018 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 SUPERFAMILY SSF56645 4 225 9.16E-58 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 Gene3D G3DSA:1.10.540.10 1 107 8.0E-25 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 105 7.7E-20 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 SUPERFAMILY SSF47203 213 363 1.05E-49 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 110 199 4.6E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 Gene3D G3DSA:2.40.110.10 109 218 6.6E-35 T 14-10-2018 A4R43_11825 fd75599d9ae6398875a91355423826a1 366 Gene3D G3DSA:1.20.140.10 219 364 3.0E-50 T 14-10-2018 A4R43_40185 10873b19c859c80430f4dbf4e8717d31 597 Gene3D G3DSA:3.50.50.60 413 595 2.1E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40185 10873b19c859c80430f4dbf4e8717d31 597 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 64 269 8.1E-11 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_40185 10873b19c859c80430f4dbf4e8717d31 597 SUPERFAMILY SSF51905 64 518 9.33E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40185 10873b19c859c80430f4dbf4e8717d31 597 Gene3D G3DSA:3.50.50.60 58 353 1.4E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40185 10873b19c859c80430f4dbf4e8717d31 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 64 86 5.7E-5 T 14-10-2018 A4R43_40185 10873b19c859c80430f4dbf4e8717d31 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 266 5.7E-5 T 14-10-2018 A4R43_06645 5f77acd988d4b9571c28e13e825c0f64 584 Gene3D G3DSA:3.20.20.150 2 271 5.3E-74 T 14-10-2018 A4R43_06645 5f77acd988d4b9571c28e13e825c0f64 584 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 402 517 1.3E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_06645 5f77acd988d4b9571c28e13e825c0f64 584 SUPERFAMILY SSF54593 280 575 8.06E-35 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_06645 5f77acd988d4b9571c28e13e825c0f64 584 Gene3D G3DSA:3.10.180.10 399 582 1.1E-30 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_06645 5f77acd988d4b9571c28e13e825c0f64 584 SUPERFAMILY SSF51658 4 269 2.9E-76 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_06645 5f77acd988d4b9571c28e13e825c0f64 584 Gene3D G3DSA:3.10.180.10 277 398 1.1E-8 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_06645 5f77acd988d4b9571c28e13e825c0f64 584 Pfam PF01261 Xylose isomerase-like TIM barrel 21 220 4.0E-37 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_06645 5f77acd988d4b9571c28e13e825c0f64 584 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 282 341 1.6E-7 T 14-10-2018 A4R43_30850 c60cac27c1132435ddf002ad979c4e62 405 PRINTS PR01035 Tetracycline resistance protein signature 29 45 6.9E-9 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_30850 c60cac27c1132435ddf002ad979c4e62 405 PRINTS PR01035 Tetracycline resistance protein signature 143 165 6.9E-9 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_30850 c60cac27c1132435ddf002ad979c4e62 405 PRINTS PR01035 Tetracycline resistance protein signature 171 191 6.9E-9 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_30850 c60cac27c1132435ddf002ad979c4e62 405 Gene3D G3DSA:1.20.1250.20 12 387 4.7E-51 T 14-10-2018 A4R43_30850 c60cac27c1132435ddf002ad979c4e62 405 SUPERFAMILY SSF103473 17 388 5.1E-52 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_30850 c60cac27c1132435ddf002ad979c4e62 405 Pfam PF07690 Major Facilitator Superfamily 24 254 5.7E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_18225 3f39725cb4389310c84b5d10d0b14976 486 Gene3D G3DSA:3.40.50.300 11 246 1.3E-72 T 14-10-2018 A4R43_18225 3f39725cb4389310c84b5d10d0b14976 486 SMART SM00487 58 258 4.5E-54 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_18225 3f39725cb4389310c84b5d10d0b14976 486 Gene3D G3DSA:3.40.50.300 252 417 1.9E-45 T 14-10-2018 A4R43_18225 3f39725cb4389310c84b5d10d0b14976 486 SUPERFAMILY SSF52540 110 393 7.89E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_18225 3f39725cb4389310c84b5d10d0b14976 486 Pfam PF00270 DEAD/DEAH box helicase 63 232 3.5E-43 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_18225 3f39725cb4389310c84b5d10d0b14976 486 Pfam PF00271 Helicase conserved C-terminal domain 268 373 1.5E-25 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_18225 3f39725cb4389310c84b5d10d0b14976 486 SMART SM00490 292 373 2.1E-31 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_12320 f29a0eda3c589a0368dd9d4470e428ad 271 Pfam PF01936 NYN domain 10 143 2.1E-31 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type A4R43_12320 f29a0eda3c589a0368dd9d4470e428ad 271 Gene3D G3DSA:3.40.50.1010 4 149 4.2E-13 T 14-10-2018 A4R43_12320 f29a0eda3c589a0368dd9d4470e428ad 271 Pfam PF12872 OST-HTH/LOTUS domain 174 242 4.5E-15 T 14-10-2018 IPR025605 OST-HTH/LOTUS domain A4R43_12320 f29a0eda3c589a0368dd9d4470e428ad 271 Gene3D G3DSA:1.10.10.1880 180 252 1.6E-26 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 Pfam PF04324 BFD-like [2Fe-2S] binding domain 369 419 3.8E-7 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 Gene3D G3DSA:1.10.10.1100 363 428 1.1E-14 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 311 1.8E-25 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 SUPERFAMILY SSF51905 2 328 2.07E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 PIRSF PIRSF037495 2 453 3.9E-116 T 14-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 5.7E-20 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.7E-20 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 5.7E-20 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.7E-20 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 Gene3D G3DSA:3.50.50.60 4 318 2.8E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 1.7E-10 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.7E-10 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 1.7E-10 T 14-10-2018 A4R43_07085 c644edd3ac956482e62e0189a04d4ae0 453 Gene3D G3DSA:3.50.50.60 116 266 2.8E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_08550 2eaa8d9eb7ef693e2a2171e9f0e64d4a 142 Gene3D G3DSA:1.10.10.10 75 141 4.4E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08550 2eaa8d9eb7ef693e2a2171e9f0e64d4a 142 SUPERFAMILY SSF46785 86 140 9.11E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08550 2eaa8d9eb7ef693e2a2171e9f0e64d4a 142 Pfam PF12840 Helix-turn-helix domain 79 127 1.8E-12 T 14-10-2018 A4R43_08550 2eaa8d9eb7ef693e2a2171e9f0e64d4a 142 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 118 133 2.6E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_08550 2eaa8d9eb7ef693e2a2171e9f0e64d4a 142 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 103 118 2.6E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_08550 2eaa8d9eb7ef693e2a2171e9f0e64d4a 142 SMART SM00418 74 142 1.2E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_10445 c9bdcd9c4bdbcdc2b51c16b0bcbe02e3 382 Gene3D G3DSA:3.40.710.10 1 368 7.9E-99 T 14-10-2018 A4R43_10445 c9bdcd9c4bdbcdc2b51c16b0bcbe02e3 382 Pfam PF00144 Beta-lactamase 5 358 4.4E-67 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_10445 c9bdcd9c4bdbcdc2b51c16b0bcbe02e3 382 SUPERFAMILY SSF56601 2 362 7.96E-85 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Gene3D G3DSA:3.40.50.300 290 397 2.3E-23 T 14-10-2018 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Pfam PF13361 UvrD-like helicase C-terminal domain 288 410 4.4E-17 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Gene3D G3DSA:1.10.150.80 623 696 5.4E-20 T 14-10-2018 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 281 6.3E-47 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 SUPERFAMILY SSF52540 13 575 5.74E-130 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Gene3D G3DSA:3.40.50.300 447 577 1.2E-26 T 14-10-2018 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Gene3D G3DSA:1.10.10.160 115 199 1.6E-72 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 SUPERFAMILY SSF47819 615 694 7.2E-21 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Pfam PF00570 HRDC domain 625 691 1.2E-19 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Pfam PF13361 UvrD-like helicase C-terminal domain 445 553 3.0E-22 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 SMART SM00341 621 697 5.6E-9 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4R43_22090 5fe0d335b116b3f31cd6472c8256a6ff 697 Gene3D G3DSA:3.40.50.300 17 283 1.6E-72 T 14-10-2018 A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 Gene3D G3DSA:3.30.70.920 59 146 1.3E-21 T 14-10-2018 A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 Pfam PF01037 Lrp/AsnC ligand binding domain 76 142 3.1E-16 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 Gene3D G3DSA:1.10.10.10 1 55 5.0E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 SUPERFAMILY SSF54909 66 150 4.42E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 5.8E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 5.8E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 5.8E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 SMART SM00344 6 112 3.0E-17 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 Pfam PF13404 AsnC-type helix-turn-helix domain 7 46 8.1E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_23695 4504e954f975b1be3ea22ad0d6661ea5 159 SUPERFAMILY SSF46785 5 79 1.23E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 1.2E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 1.2E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.2E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.2E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 Gene3D G3DSA:3.40.50.720 1 261 9.2E-62 T 14-10-2018 A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 SUPERFAMILY SSF51735 9 258 9.61E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 257 1.0E-39 T 14-10-2018 A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 7.0E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07340 f1bed2c22ccaaa6d92eb14cdddeaec92 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 7.0E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_00165 27eb528c035d76e9a9cbc3a1bf0eece8 157 Pfam PF02082 Transcriptional regulator 4 83 4.0E-20 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type A4R43_00165 27eb528c035d76e9a9cbc3a1bf0eece8 157 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 5 138 3.9E-25 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type A4R43_00165 27eb528c035d76e9a9cbc3a1bf0eece8 157 Gene3D G3DSA:1.10.10.10 1 145 1.4E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00165 27eb528c035d76e9a9cbc3a1bf0eece8 157 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A4R43_00165 27eb528c035d76e9a9cbc3a1bf0eece8 157 SUPERFAMILY SSF46785 3 140 8.93E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20520 8446324d834d1f963011f0714fc8ae67 240 SUPERFAMILY SSF51621 3 237 5.83E-55 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_20520 8446324d834d1f963011f0714fc8ae67 240 Gene3D G3DSA:3.20.20.60 1 221 3.6E-66 T 14-10-2018 A4R43_20520 8446324d834d1f963011f0714fc8ae67 240 Pfam PF13714 Phosphoenolpyruvate phosphomutase 6 227 3.3E-67 T 14-10-2018 A4R43_20550 3a01e2cb014418f77a866088e52109d6 321 Pfam PF03308 ArgK protein 22 283 3.0E-95 T 14-10-2018 A4R43_20550 3a01e2cb014418f77a866088e52109d6 321 SMART SM00382 49 220 0.0013 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_20550 3a01e2cb014418f77a866088e52109d6 321 SUPERFAMILY SSF52540 6 317 1.44E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20550 3a01e2cb014418f77a866088e52109d6 321 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 20 316 6.4E-100 T 14-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_20550 3a01e2cb014418f77a866088e52109d6 321 Gene3D G3DSA:3.40.50.300 45 256 1.3E-83 T 14-10-2018 A4R43_17775 690a64e6d4beb4670c7682b8949f73d9 235 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 230 4.5E-45 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4R43_17775 690a64e6d4beb4670c7682b8949f73d9 235 Gene3D G3DSA:3.90.550.10 8 233 2.6E-59 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_17775 690a64e6d4beb4670c7682b8949f73d9 235 SUPERFAMILY SSF53448 9 230 4.73E-41 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_17775 690a64e6d4beb4670c7682b8949f73d9 235 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 107 114 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 Gene3D G3DSA:3.40.50.720 1 359 7.7E-72 T 14-10-2018 A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 Gene3D G3DSA:3.40.50.720 360 618 5.8E-62 T 14-10-2018 A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 377 561 1.8E-5 T 14-10-2018 A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 SUPERFAMILY SSF51735 373 594 1.24E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 SUPERFAMILY SSF51735 2 362 1.46E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 378 395 1.2E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 501 517 1.2E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 452 463 1.2E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 527 546 1.2E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 Pfam PF07993 Male sterility protein 6 233 5.9E-46 T 14-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 514 542 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 Pfam PF00106 short chain dehydrogenase 378 566 1.0E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 452 463 8.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 507 515 8.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23760 91ff10de83ec40deb3eaf2a93d2b9ac6 664 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 527 546 8.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_02080 2ff52024afaa059c92a60d8d9835a4f7 457 Gene3D G3DSA:3.40.605.10 7 445 5.8E-148 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_02080 2ff52024afaa059c92a60d8d9835a4f7 457 SUPERFAMILY SSF53720 3 454 1.28E-138 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_02080 2ff52024afaa059c92a60d8d9835a4f7 457 Pfam PF00171 Aldehyde dehydrogenase family 3 449 2.7E-136 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_02080 2ff52024afaa059c92a60d8d9835a4f7 457 Gene3D G3DSA:3.40.309.10 230 419 5.8E-148 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_35655 e212193152a87cc4efcaa409802eea57 209 Pfam PF04542 Sigma-70 region 2 36 101 7.1E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_35655 e212193152a87cc4efcaa409802eea57 209 Pfam PF08281 Sigma-70, region 4 134 184 3.8E-17 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_35655 e212193152a87cc4efcaa409802eea57 209 SUPERFAMILY SSF88946 31 114 1.0E-24 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_35655 e212193152a87cc4efcaa409802eea57 209 Gene3D G3DSA:1.10.10.10 132 194 2.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35655 e212193152a87cc4efcaa409802eea57 209 SUPERFAMILY SSF88659 110 190 1.63E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_35655 e212193152a87cc4efcaa409802eea57 209 Gene3D G3DSA:1.10.1740.10 22 103 2.6E-25 T 14-10-2018 A4R43_35655 e212193152a87cc4efcaa409802eea57 209 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 186 2.0E-30 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_22485 468f3e2614ba29354470368c96482ba8 564 Gene3D G3DSA:3.50.30.80 375 529 7.6E-48 T 14-10-2018 A4R43_22485 468f3e2614ba29354470368c96482ba8 564 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_22485 468f3e2614ba29354470368c96482ba8 564 Pfam PF00920 Dehydratase family 41 554 2.8E-155 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_22485 468f3e2614ba29354470368c96482ba8 564 SUPERFAMILY SSF143975 14 374 2.35E-101 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_22485 468f3e2614ba29354470368c96482ba8 564 SUPERFAMILY SSF52016 376 560 3.53E-53 T 14-10-2018 A4R43_21160 c0e4ee7380b99ff347a5299271738693 336 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 8 125 4.4E-13 T 14-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A4R43_21160 c0e4ee7380b99ff347a5299271738693 336 SUPERFAMILY SSF51735 7 160 1.95E-16 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_21160 c0e4ee7380b99ff347a5299271738693 336 Gene3D G3DSA:3.40.50.720 4 159 3.4E-23 T 14-10-2018 A4R43_18140 7e386007ae830380961ad35b1fa99143 372 Pfam PF00487 Fatty acid desaturase 65 332 2.3E-33 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_15170 177d93a184e2d75dd9f08888dd562828 431 SUPERFAMILY SSF52317 58 236 1.28E-36 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_15170 177d93a184e2d75dd9f08888dd562828 431 SUPERFAMILY SSF52317 268 343 6.87E-7 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_15170 177d93a184e2d75dd9f08888dd562828 431 Pfam PF01965 DJ-1/PfpI family 60 219 5.1E-13 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_15170 177d93a184e2d75dd9f08888dd562828 431 Gene3D G3DSA:3.40.50.880 259 362 5.5E-8 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_15170 177d93a184e2d75dd9f08888dd562828 431 Gene3D G3DSA:3.40.50.880 40 251 3.1E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_27610 84cb5d7f5caabe1faaed1209e0b8f0eb 919 Gene3D G3DSA:3.40.50.300 374 652 1.2E-49 T 14-10-2018 A4R43_27610 84cb5d7f5caabe1faaed1209e0b8f0eb 919 Pfam PF01580 FtsK/SpoIIIE family 381 570 1.3E-20 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_27610 84cb5d7f5caabe1faaed1209e0b8f0eb 919 SUPERFAMILY SSF52540 388 595 2.61E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41575 49da35a54a8d2f7de76977ef4096bd97 310 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 22 303 1.3E-55 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4R43_41575 49da35a54a8d2f7de76977ef4096bd97 310 Pfam PF03186 CobD/Cbib protein 17 293 4.8E-89 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4R43_41575 49da35a54a8d2f7de76977ef4096bd97 310 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 310 88.253 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4R43_30510 c53ff8b8c9b0597b3284f7e3df782fa8 603 PRINTS PR01806 Virulence factor MviN signature 109 128 5.3E-20 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4R43_30510 c53ff8b8c9b0597b3284f7e3df782fa8 603 PRINTS PR01806 Virulence factor MviN signature 128 144 5.3E-20 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4R43_30510 c53ff8b8c9b0597b3284f7e3df782fa8 603 PRINTS PR01806 Virulence factor MviN signature 341 367 5.3E-20 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4R43_30510 c53ff8b8c9b0597b3284f7e3df782fa8 603 PRINTS PR01806 Virulence factor MviN signature 229 250 5.3E-20 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4R43_30510 c53ff8b8c9b0597b3284f7e3df782fa8 603 PRINTS PR01806 Virulence factor MviN signature 205 229 5.3E-20 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4R43_30510 c53ff8b8c9b0597b3284f7e3df782fa8 603 PRINTS PR01806 Virulence factor MviN signature 439 458 5.3E-20 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4R43_30510 c53ff8b8c9b0597b3284f7e3df782fa8 603 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 78 590 2.4E-78 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4R43_30510 c53ff8b8c9b0597b3284f7e3df782fa8 603 Pfam PF03023 MviN-like protein 109 550 7.4E-86 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 136 156 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 Pfam PF00919 Uncharacterized protein family UPF0004 1 89 7.9E-21 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 1 424 2.6E-141 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 SMART SM00729 132 350 6.0E-57 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 SUPERFAMILY SSF102114 117 355 5.49E-58 T 14-10-2018 A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 Gene3D G3DSA:3.40.50.12160 1 120 2.0E-26 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 429 63.426 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 1 399 9.2E-131 T 14-10-2018 A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 Pfam PF04055 Radical SAM superfamily 136 307 2.4E-29 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_16875 4265c11c66263a2e65e9b7e299a79247 474 Gene3D G3DSA:3.80.30.20 130 364 9.9E-90 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4R43_37845 5f1ae3c228fcd29de45ca94681737c9f 355 SUPERFAMILY SSF53807 49 322 5.89E-44 T 14-10-2018 A4R43_37845 5f1ae3c228fcd29de45ca94681737c9f 355 Pfam PF01497 Periplasmic binding protein 121 305 8.6E-15 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_37845 5f1ae3c228fcd29de45ca94681737c9f 355 Gene3D G3DSA:3.40.50.1980 190 344 1.1E-41 T 14-10-2018 A4R43_37845 5f1ae3c228fcd29de45ca94681737c9f 355 Gene3D G3DSA:3.40.50.1980 46 185 1.4E-38 T 14-10-2018 A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 Gene3D G3DSA:3.40.50.720 1 252 2.4E-73 T 14-10-2018 A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 SUPERFAMILY SSF51735 1 252 2.79E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_08080 adc0145a5cfadad10ddf6213c269cedb 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 3.8E-57 T 14-10-2018 A4R43_29200 f4e4fe903e75e712e3e53f8a54eed85f 647 SMART SM00421 562 619 2.9E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_29200 f4e4fe903e75e712e3e53f8a54eed85f 647 Gene3D G3DSA:1.25.40.10 295 494 2.3E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_29200 f4e4fe903e75e712e3e53f8a54eed85f 647 Gene3D G3DSA:1.10.10.10 507 627 5.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29200 f4e4fe903e75e712e3e53f8a54eed85f 647 SUPERFAMILY SSF46894 553 616 9.18E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_29200 f4e4fe903e75e712e3e53f8a54eed85f 647 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 565 579 1.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_29200 f4e4fe903e75e712e3e53f8a54eed85f 647 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 595 607 1.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_29200 f4e4fe903e75e712e3e53f8a54eed85f 647 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 579 595 1.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_29200 f4e4fe903e75e712e3e53f8a54eed85f 647 Pfam PF00196 Bacterial regulatory proteins, luxR family 564 615 5.1E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25865 f8ea4bfdca927d188b9b42b5a2674f6e 253 SUPERFAMILY SSF54506 2 251 3.14E-71 T 14-10-2018 A4R43_25865 f8ea4bfdca927d188b9b42b5a2674f6e 253 Pfam PF02567 Phenazine biosynthesis-like protein 6 249 8.1E-57 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4R43_25865 f8ea4bfdca927d188b9b42b5a2674f6e 253 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 82 1.5E-22 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4R43_25865 f8ea4bfdca927d188b9b42b5a2674f6e 253 Gene3D G3DSA:3.10.310.10 3 245 9.9E-83 T 14-10-2018 A4R43_25865 f8ea4bfdca927d188b9b42b5a2674f6e 253 PIRSF PIRSF016184 1 253 1.3E-44 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4R43_25865 f8ea4bfdca927d188b9b42b5a2674f6e 253 Gene3D G3DSA:3.10.310.10 109 241 9.9E-83 T 14-10-2018 A4R43_18325 b2726bac5b2fca1aa6cba22999eb8963 383 Pfam PF04551 GcpE protein 21 361 2.9E-136 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4R43_18325 b2726bac5b2fca1aa6cba22999eb8963 383 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.674 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4R43_18325 b2726bac5b2fca1aa6cba22999eb8963 383 Gene3D G3DSA:3.30.413.10 272 372 2.6E-36 T 14-10-2018 A4R43_18325 b2726bac5b2fca1aa6cba22999eb8963 383 SUPERFAMILY SSF56014 276 363 3.66E-11 T 14-10-2018 A4R43_18325 b2726bac5b2fca1aa6cba22999eb8963 383 PIRSF PIRSF004640 12 372 4.9E-146 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4R43_18325 b2726bac5b2fca1aa6cba22999eb8963 383 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 2.5E-129 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4R43_18325 b2726bac5b2fca1aa6cba22999eb8963 383 Gene3D G3DSA:3.20.20.20 13 271 1.3E-107 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_18325 b2726bac5b2fca1aa6cba22999eb8963 383 SUPERFAMILY SSF51717 46 219 3.22E-10 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 Gene3D G3DSA:3.30.565.10 210 361 8.2E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 SUPERFAMILY SSF55874 210 360 1.17E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 SMART SM00304 89 142 9.1E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 SMART SM00388 143 207 2.6E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 Pfam PF00512 His Kinase A (phospho-acceptor) domain 144 206 9.7E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 Pfam PF00672 HAMP domain 90 138 1.5E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 SMART SM00387 249 362 8.4E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 SUPERFAMILY SSF47384 126 206 4.71E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 360 1.4E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 SUPERFAMILY SSF158472 91 139 7.19E-9 T 14-10-2018 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 301 5.5E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 359 5.5E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 340 5.5E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_21415 a48394dd17dfae1aed14778ccef9c320 363 Gene3D G3DSA:1.10.287.130 93 209 1.7E-25 T 14-10-2018 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 8.3E-16 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 Gene3D G3DSA:2.40.30.10 208 337 7.6E-53 T 14-10-2018 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 SUPERFAMILY SSF52540 6 221 2.64E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 Gene3D G3DSA:2.40.30.10 341 395 3.8E-27 T 14-10-2018 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 1.2E-13 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.0E-57 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 SUPERFAMILY SSF50465 305 397 7.48E-35 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.131 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 Gene3D G3DSA:3.40.50.300 1 205 1.5E-69 T 14-10-2018 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 SUPERFAMILY SSF50447 207 304 8.94E-31 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 395 8.4E-220 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4R43_33830 fa49187f0e06689682ae7a19c24e2857 397 Pfam PF03143 Elongation factor Tu C-terminal domain 302 395 2.7E-32 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A4R43_21975 b5ed1dc676d11ebdbf9b23ddc2f50a84 302 SUPERFAMILY SSF51556 25 300 1.23E-42 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_21975 b5ed1dc676d11ebdbf9b23ddc2f50a84 302 Gene3D G3DSA:3.20.20.140 23 300 1.8E-34 T 14-10-2018 A4R43_21975 b5ed1dc676d11ebdbf9b23ddc2f50a84 302 Pfam PF04909 Amidohydrolase 25 300 5.4E-32 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_35355 113016f1e3d6a2d56be5d881226743d8 528 Gene3D G3DSA:3.90.226.10 269 528 6.3E-88 T 14-10-2018 A4R43_35355 113016f1e3d6a2d56be5d881226743d8 528 SUPERFAMILY SSF52096 12 264 7.71E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_35355 113016f1e3d6a2d56be5d881226743d8 528 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 137 155 3.4E-8 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4R43_35355 113016f1e3d6a2d56be5d881226743d8 528 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 103 117 3.4E-8 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4R43_35355 113016f1e3d6a2d56be5d881226743d8 528 SUPERFAMILY SSF52096 252 528 1.3E-85 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_35355 113016f1e3d6a2d56be5d881226743d8 528 Pfam PF01039 Carboxyl transferase domain 36 526 7.2E-177 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_35355 113016f1e3d6a2d56be5d881226743d8 528 Gene3D G3DSA:3.90.226.10 8 266 4.5E-90 T 14-10-2018 A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 SMART SM00855 132 246 4.7E-8 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 Gene3D G3DSA:3.40.50.1240 131 291 1.7E-27 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 SUPERFAMILY SSF53254 131 254 4.28E-16 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 SUPERFAMILY SSF55811 9 123 3.11E-28 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 PRINTS PR00502 NUDIX hydrolase family signature 37 52 8.9E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 PRINTS PR00502 NUDIX hydrolase family signature 23 37 8.9E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 Gene3D G3DSA:3.90.79.10 1 129 1.1E-35 T 14-10-2018 A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 133 210 4.2E-9 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 ProSitePatterns PS00893 Nudix box signature. 28 49 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_19575 08c6ffdbea419d82c3f22a8fd955de27 319 Pfam PF00293 NUDIX domain 11 122 1.8E-18 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_28115 538366f37c5108cc527ee9dc0e3157a2 336 Gene3D G3DSA:1.10.540.10 3 110 1.7E-18 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_28115 538366f37c5108cc527ee9dc0e3157a2 336 SUPERFAMILY SSF47203 252 324 8.57E-5 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_28115 538366f37c5108cc527ee9dc0e3157a2 336 SUPERFAMILY SSF56645 4 209 1.01E-32 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_28115 538366f37c5108cc527ee9dc0e3157a2 336 Gene3D G3DSA:2.40.110.10 119 207 1.6E-7 T 14-10-2018 A4R43_28115 538366f37c5108cc527ee9dc0e3157a2 336 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 109 1.7E-10 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_16045 e74d2e3aa13bf73e56c02caaf07e11db 392 Gene3D G3DSA:2.40.110.10 112 207 4.5E-35 T 14-10-2018 A4R43_16045 e74d2e3aa13bf73e56c02caaf07e11db 392 PIRSF PIRSF016578 2 392 2.6E-137 T 14-10-2018 A4R43_16045 e74d2e3aa13bf73e56c02caaf07e11db 392 SUPERFAMILY SSF47203 230 369 1.74E-16 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16045 e74d2e3aa13bf73e56c02caaf07e11db 392 Gene3D G3DSA:1.20.140.10 208 392 1.2E-52 T 14-10-2018 A4R43_16045 e74d2e3aa13bf73e56c02caaf07e11db 392 SUPERFAMILY SSF56645 15 206 8.51E-38 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16045 e74d2e3aa13bf73e56c02caaf07e11db 392 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 238 370 6.4E-40 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4R43_16045 e74d2e3aa13bf73e56c02caaf07e11db 392 Gene3D G3DSA:1.10.540.10 3 111 2.0E-32 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16045 e74d2e3aa13bf73e56c02caaf07e11db 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 85 1.4E-6 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 Pfam PF13560 Helix-turn-helix domain 18 80 7.1E-11 T 14-10-2018 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 SUPERFAMILY SSF52540 105 366 3.89E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 Gene3D G3DSA:1.25.40.10 667 799 2.0E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 Gene3D G3DSA:1.25.40.10 499 666 5.2E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 SMART SM00028 715 748 160.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 SMART SM00028 588 621 0.055 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 SMART SM00028 675 708 140.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 Gene3D G3DSA:1.10.260.40 14 92 1.9E-10 T 14-10-2018 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 Pfam PF13424 Tetratricopeptide repeat 587 652 2.2E-8 T 14-10-2018 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 SUPERFAMILY SSF47413 17 80 4.83E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 Pfam PF00931 NB-ARC domain 121 370 4.1E-9 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 Gene3D G3DSA:3.40.50.300 103 257 5.0E-28 T 14-10-2018 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 SUPERFAMILY SSF48452 540 755 1.77E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 PRINTS PR00364 Disease resistance protein signature 299 313 3.7E-10 T 14-10-2018 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 PRINTS PR00364 Disease resistance protein signature 214 228 3.7E-10 T 14-10-2018 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 PRINTS PR00364 Disease resistance protein signature 137 152 3.7E-10 T 14-10-2018 A4R43_12145 ff6d9d655ceb6a04452e9624ef35f480 803 SMART SM00530 22 78 1.2E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_29995 92b48475ee4aa12de2814d8009d465a6 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 18 54 6.8E-8 T 14-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal A4R43_29995 92b48475ee4aa12de2814d8009d465a6 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 55 118 9.2E-24 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A4R43_29995 92b48475ee4aa12de2814d8009d465a6 136 SUPERFAMILY SSF50249 3 124 4.63E-36 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_14365 d0d677e3d35fccd576dd6c6e8295ee0e 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.03 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4R43_14365 d0d677e3d35fccd576dd6c6e8295ee0e 64 Pfam PF01632 Ribosomal protein L35 2 62 1.6E-22 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14365 d0d677e3d35fccd576dd6c6e8295ee0e 64 SUPERFAMILY SSF143034 2 63 7.19E-20 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_14365 d0d677e3d35fccd576dd6c6e8295ee0e 64 Gene3D G3DSA:2.40.50.530 1 63 6.4E-23 T 14-10-2018 A4R43_14365 d0d677e3d35fccd576dd6c6e8295ee0e 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.2E-14 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4R43_14365 d0d677e3d35fccd576dd6c6e8295ee0e 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.2E-14 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4R43_14365 d0d677e3d35fccd576dd6c6e8295ee0e 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.2E-14 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4R43_14365 d0d677e3d35fccd576dd6c6e8295ee0e 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 6.5E-22 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4R43_29025 86b389ff3b2976952f7ace540073f3c4 252 Pfam PF00005 ABC transporter 17 163 1.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_29025 86b389ff3b2976952f7ace540073f3c4 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_29025 86b389ff3b2976952f7ace540073f3c4 252 SUPERFAMILY SSF52540 1 235 3.59E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29025 86b389ff3b2976952f7ace540073f3c4 252 Gene3D G3DSA:3.40.50.300 1 251 1.9E-85 T 14-10-2018 A4R43_29025 86b389ff3b2976952f7ace540073f3c4 252 SMART SM00382 26 221 7.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 Gene3D G3DSA:1.10.540.10 13 121 1.2E-28 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 Gene3D G3DSA:2.40.110.10 123 236 2.3E-38 T 14-10-2018 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 SUPERFAMILY SSF47203 230 380 1.77E-55 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 PIRSF PIRSF016578 3 379 2.1E-15 T 14-10-2018 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 218 9.7E-26 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 Gene3D G3DSA:1.20.140.10 237 381 7.2E-53 T 14-10-2018 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 2.1E-24 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 SUPERFAMILY SSF56645 7 231 3.4E-69 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_25550 3449c0ee10a269a47248b39b547668fe 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 1.4E-47 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_14805 e6d86a96cac1f8f16653efcce7e8839f 277 Gene3D G3DSA:3.40.630.30 2 272 8.4E-23 T 14-10-2018 A4R43_14805 e6d86a96cac1f8f16653efcce7e8839f 277 Pfam PF00583 Acetyltransferase (GNAT) family 147 261 1.4E-8 T 14-10-2018 IPR000182 GNAT domain A4R43_14805 e6d86a96cac1f8f16653efcce7e8839f 277 SUPERFAMILY SSF55729 48 266 1.03E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_40345 c0f619cd5f690dd4681e3eb325a8033d 581 SUPERFAMILY SSF53474 326 578 4.31E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40345 c0f619cd5f690dd4681e3eb325a8033d 581 Gene3D G3DSA:2.120.10.30 2 117 5.4E-10 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_40345 c0f619cd5f690dd4681e3eb325a8033d 581 Gene3D G3DSA:3.40.50.1820 319 581 1.0E-67 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40345 c0f619cd5f690dd4681e3eb325a8033d 581 Pfam PF00326 Prolyl oligopeptidase family 382 578 1.3E-46 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_40345 c0f619cd5f690dd4681e3eb325a8033d 581 SUPERFAMILY SSF82171 12 317 5.49E-15 T 14-10-2018 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 10 261 2.1E-89 T 14-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 Gene3D G3DSA:3.30.540.10 4 142 1.7E-42 T 14-10-2018 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 SUPERFAMILY SSF56655 7 261 4.19E-75 T 14-10-2018 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 Gene3D G3DSA:3.40.190.80 148 261 1.2E-22 T 14-10-2018 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 Pfam PF00459 Inositol monophosphatase family 10 241 1.1E-50 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 3.9E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 3.9E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 3.9E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_35255 8aa2124dcb271952a29ffd743372332f 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 3.9E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 Gene3D G3DSA:3.40.50.12740 3 215 1.1E-65 T 14-10-2018 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 Pfam PF00072 Response regulator receiver domain 5 116 8.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 SMART SM00421 153 210 1.0E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 SMART SM00448 3 115 3.4E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 SUPERFAMILY SSF52172 3 182 8.99E-30 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 9.5E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 9.5E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 9.5E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15740 7cb29c9a1e3a4c552b5b95bd3aac8ba8 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 8.4E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39485 c675ed9235a355834507f2672ba8e80a 257 SUPERFAMILY SSF52096 3 254 2.03E-68 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_39485 c675ed9235a355834507f2672ba8e80a 257 Gene3D G3DSA:3.90.226.10 1 197 1.6E-53 T 14-10-2018 A4R43_39485 c675ed9235a355834507f2672ba8e80a 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 253 2.0E-46 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_39485 c675ed9235a355834507f2672ba8e80a 257 Gene3D G3DSA:1.10.12.10 200 254 4.4E-17 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_37875 a81bd0045d4c8058b28ff440c5e3cead 411 SMART SM00507 315 367 1.7E-9 T 14-10-2018 IPR003615 HNH nuclease A4R43_37875 a81bd0045d4c8058b28ff440c5e3cead 411 Pfam PF02720 Domain of unknown function (DUF222) 22 324 5.5E-40 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_37875 a81bd0045d4c8058b28ff440c5e3cead 411 Pfam PF01844 HNH endonuclease 331 370 6.5E-6 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A4R43_18735 aaf617c041a6ed63e6daeb0f9a42d03e 107 SUPERFAMILY SSF46785 11 105 4.38E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_18735 aaf617c041a6ed63e6daeb0f9a42d03e 107 Pfam PF03551 Transcriptional regulator PadR-like family 15 87 1.7E-18 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_18735 aaf617c041a6ed63e6daeb0f9a42d03e 107 Gene3D G3DSA:1.10.10.10 2 107 9.4E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23385 d3f2dcd06cf704381cbf8eaba8a6a38b 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 6.8E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_23385 d3f2dcd06cf704381cbf8eaba8a6a38b 235 SMART SM00862 148 223 7.1E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_23385 d3f2dcd06cf704381cbf8eaba8a6a38b 235 Gene3D G3DSA:1.10.10.10 129 231 3.5E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23385 d3f2dcd06cf704381cbf8eaba8a6a38b 235 Pfam PF00072 Response regulator receiver domain 5 114 9.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_23385 d3f2dcd06cf704381cbf8eaba8a6a38b 235 Gene3D G3DSA:3.40.50.2300 1 128 7.3E-36 T 14-10-2018 A4R43_23385 d3f2dcd06cf704381cbf8eaba8a6a38b 235 SUPERFAMILY SSF52172 3 171 8.82E-39 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_23385 d3f2dcd06cf704381cbf8eaba8a6a38b 235 SMART SM00448 3 114 9.9E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_31185 29fbb5184f3c30b75c5d27984ba9066b 156 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 153 3.1E-14 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_31185 29fbb5184f3c30b75c5d27984ba9066b 156 Gene3D G3DSA:3.30.530.20 4 156 6.7E-34 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_31185 29fbb5184f3c30b75c5d27984ba9066b 156 SUPERFAMILY SSF55961 4 154 6.14E-20 T 14-10-2018 A4R43_02430 4da3e2c5ae7348202e3c33f8b850ff63 98 Gene3D G3DSA:3.30.70.100 1 98 6.5E-21 T 14-10-2018 A4R43_02430 4da3e2c5ae7348202e3c33f8b850ff63 98 Pfam PF07045 Domain of unknown function (DUF1330) 3 97 1.3E-18 T 14-10-2018 IPR010753 Domain of unknown function DUF1330 A4R43_02430 4da3e2c5ae7348202e3c33f8b850ff63 98 SUPERFAMILY SSF54909 2 97 3.22E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_04805 fdd790e2144f50ef7590600e370c2353 327 SUPERFAMILY SSF50129 1 153 5.03E-29 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_04805 fdd790e2144f50ef7590600e370c2353 327 Pfam PF00107 Zinc-binding dehydrogenase 155 282 5.0E-27 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_04805 fdd790e2144f50ef7590600e370c2353 327 SMART SM00829 10 325 2.1E-12 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_04805 fdd790e2144f50ef7590600e370c2353 327 SUPERFAMILY SSF51735 124 278 2.03E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04805 fdd790e2144f50ef7590600e370c2353 327 Gene3D G3DSA:3.90.180.10 9 324 2.6E-84 T 14-10-2018 A4R43_04805 fdd790e2144f50ef7590600e370c2353 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 93 2.1E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_04805 fdd790e2144f50ef7590600e370c2353 327 Gene3D G3DSA:3.40.50.720 128 271 2.6E-84 T 14-10-2018 A4R43_02745 5ecd3d4e0f60c8aef1199b9507814a04 360 Pfam PF00155 Aminotransferase class I and II 31 354 2.2E-35 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_02745 5ecd3d4e0f60c8aef1199b9507814a04 360 Gene3D G3DSA:3.40.640.10 38 256 3.7E-76 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_02745 5ecd3d4e0f60c8aef1199b9507814a04 360 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 203 216 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4R43_02745 5ecd3d4e0f60c8aef1199b9507814a04 360 SUPERFAMILY SSF53383 34 358 8.25E-72 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_02745 5ecd3d4e0f60c8aef1199b9507814a04 360 Gene3D G3DSA:3.90.1150.10 8 352 3.7E-76 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_09925 695a0d429d970c296a60a48184654ffb 544 SUPERFAMILY SSF56801 9 538 2.35E-134 T 14-10-2018 A4R43_09925 695a0d429d970c296a60a48184654ffb 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_09925 695a0d429d970c296a60a48184654ffb 544 Gene3D G3DSA:2.30.38.10 355 436 2.0E-26 T 14-10-2018 A4R43_09925 695a0d429d970c296a60a48184654ffb 544 Gene3D G3DSA:3.40.50.980 22 179 1.1E-41 T 14-10-2018 A4R43_09925 695a0d429d970c296a60a48184654ffb 544 Gene3D G3DSA:3.30.300.310 438 542 4.0E-31 T 14-10-2018 A4R43_09925 695a0d429d970c296a60a48184654ffb 544 Pfam PF00501 AMP-binding enzyme 33 442 6.2E-85 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_09925 695a0d429d970c296a60a48184654ffb 544 Gene3D G3DSA:3.40.50.980 183 354 1.8E-55 T 14-10-2018 A4R43_09925 695a0d429d970c296a60a48184654ffb 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 527 1.1E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 TIGRFAM TIGR00422 valS: valine--tRNA ligase 12 851 0.0 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 Gene3D G3DSA:3.40.50.620 31 527 2.9E-296 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 807 871 2.3E-16 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 SUPERFAMILY SSF50677 201 340 2.09E-54 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 SUPERFAMILY SSF52374 10 574 2.16E-137 T 14-10-2018 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 SUPERFAMILY SSF46589 807 871 2.3E-13 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 52 63 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 Gene3D G3DSA:1.10.730.10 11 738 2.9E-296 T 14-10-2018 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 Gene3D G3DSA:3.90.740.10 184 348 2.9E-296 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 9.8E-39 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 PRINTS PR00986 Valyl-tRNA synthetase signature 237 254 9.8E-39 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 PRINTS PR00986 Valyl-tRNA synthetase signature 352 365 9.8E-39 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 PRINTS PR00986 Valyl-tRNA synthetase signature 45 56 9.8E-39 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 PRINTS PR00986 Valyl-tRNA synthetase signature 446 467 9.8E-39 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 Gene3D G3DSA:1.10.287.380 800 872 1.3E-15 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 SUPERFAMILY SSF47323 578 819 7.1E-52 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 24 565 3.6E-195 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 Pfam PF08264 Anticodon-binding domain of tRNA 608 750 2.7E-38 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A4R43_39110 5a26d4ae2158b3a7348c56ac4e3c4e9f 874 Hamap MF_02004 Valine--tRNA ligase [valS]. 11 872 15.23 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 SUPERFAMILY SSF53850 90 292 3.44E-28 T 14-10-2018 A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 Gene3D G3DSA:3.40.190.10 90 290 5.9E-48 T 14-10-2018 A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 Gene3D G3DSA:3.40.190.10 171 266 5.9E-48 T 14-10-2018 A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 Gene3D G3DSA:1.10.10.10 1 88 5.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.8E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.7E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.7E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.7E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 SUPERFAMILY SSF46785 2 85 2.31E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39915 c056601e4d327193841c398cdb6eeb52 299 Pfam PF03466 LysR substrate binding domain 95 293 3.7E-14 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 Pfam PF00672 HAMP domain 188 236 1.5E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 302 5.8E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 SMART SM00387 344 455 9.8E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 SUPERFAMILY SSF158472 189 236 1.06E-9 T 14-10-2018 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 SMART SM00388 240 303 5.6E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 SMART SM00304 187 239 1.2E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 3.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 3.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 3.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 3.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 Gene3D G3DSA:1.10.287.130 191 303 2.1E-30 T 14-10-2018 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 SUPERFAMILY SSF55874 293 452 7.6E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 Gene3D G3DSA:3.30.565.10 337 454 7.7E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 SUPERFAMILY SSF47384 223 302 5.69E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_36980 94aae54f1044045bbe9c381636dff1d4 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 452 5.7E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_28335 81fa413b9af7bab8ca069798006546d7 200 SUPERFAMILY SSF46689 5 74 1.5E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_28335 81fa413b9af7bab8ca069798006546d7 200 Gene3D G3DSA:1.10.357.10 1 199 4.2E-43 T 14-10-2018 A4R43_28335 81fa413b9af7bab8ca069798006546d7 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 3.7E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28335 81fa413b9af7bab8ca069798006546d7 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28335 81fa413b9af7bab8ca069798006546d7 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28335 81fa413b9af7bab8ca069798006546d7 200 SUPERFAMILY SSF48498 81 193 1.51E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_30705 55ff641614f48de18c54e5df45fb6f78 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 126 2.3E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_30705 55ff641614f48de18c54e5df45fb6f78 138 Gene3D G3DSA:3.30.720.110 76 134 9.7E-14 T 14-10-2018 A4R43_30705 55ff641614f48de18c54e5df45fb6f78 138 Gene3D G3DSA:3.30.720.120 2 67 6.3E-13 T 14-10-2018 A4R43_30705 55ff641614f48de18c54e5df45fb6f78 138 SUPERFAMILY SSF54593 4 134 6.04E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 14 41 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 SUPERFAMILY SSF55653 59 149 2.49E-21 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 SUPERFAMILY SSF55658 3 58 5.76E-17 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 Gene3D G3DSA:3.40.5.10 2 60 1.6E-21 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 2 151 24.716 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 Gene3D G3DSA:3.10.430.100 62 151 2.4E-23 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 3 47 1.1E-20 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 150 1.1E-24 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal A4R43_30755 688ec5cd15cd4009433e41f16620ef58 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 3 150 2.1E-35 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_23715 45d8c174773d308eea9dbad0927aeaf0 385 PIRSF PIRSF001434 5 385 7.6E-143 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_23715 45d8c174773d308eea9dbad0927aeaf0 385 Gene3D G3DSA:3.40.640.10 4 255 3.1E-101 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_23715 45d8c174773d308eea9dbad0927aeaf0 385 Gene3D G3DSA:3.90.1150.10 256 385 1.9E-47 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_23715 45d8c174773d308eea9dbad0927aeaf0 385 SUPERFAMILY SSF53383 12 384 2.18E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_23715 45d8c174773d308eea9dbad0927aeaf0 385 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_23715 45d8c174773d308eea9dbad0927aeaf0 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 384 1.5E-142 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_36765 c1a9c6f0c4f2a185c48a054267332c09 352 SUPERFAMILY SSF47413 7 64 3.38E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_36765 c1a9c6f0c4f2a185c48a054267332c09 352 Gene3D G3DSA:1.10.260.40 5 79 2.5E-9 T 14-10-2018 A4R43_36765 c1a9c6f0c4f2a185c48a054267332c09 352 Gene3D G3DSA:1.25.40.10 122 349 1.2E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_36765 c1a9c6f0c4f2a185c48a054267332c09 352 Pfam PF13560 Helix-turn-helix domain 9 70 3.8E-13 T 14-10-2018 A4R43_36765 c1a9c6f0c4f2a185c48a054267332c09 352 SMART SM00530 12 68 1.8E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_36765 c1a9c6f0c4f2a185c48a054267332c09 352 SUPERFAMILY SSF48452 143 332 1.96E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28240 e3d893157904686b8a3c9a02832f45b8 186 SUPERFAMILY SSF56784 2 185 1.04E-30 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_28240 e3d893157904686b8a3c9a02832f45b8 186 Gene3D G3DSA:3.40.50.1000 3 175 3.9E-31 T 14-10-2018 IPR023214 HAD superfamily A4R43_28240 e3d893157904686b8a3c9a02832f45b8 186 Pfam PF13419 Haloacid dehalogenase-like hydrolase 52 158 3.7E-19 T 14-10-2018 A4R43_28240 e3d893157904686b8a3c9a02832f45b8 186 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 2 152 1.1E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_28240 e3d893157904686b8a3c9a02832f45b8 186 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 2 158 7.4E-13 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_28240 e3d893157904686b8a3c9a02832f45b8 186 Gene3D G3DSA:1.10.260.80 12 62 3.9E-31 T 14-10-2018 A4R43_35825 bafa02c33384290c28fa372acc5f960c 542 SUPERFAMILY SSF52540 91 377 1.21E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35825 bafa02c33384290c28fa372acc5f960c 542 Pfam PF00270 DEAD/DEAH box helicase 46 206 2.7E-48 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_35825 bafa02c33384290c28fa372acc5f960c 542 Gene3D G3DSA:3.40.50.300 232 402 1.2E-49 T 14-10-2018 A4R43_35825 bafa02c33384290c28fa372acc5f960c 542 Gene3D G3DSA:3.40.50.300 7 226 1.2E-69 T 14-10-2018 A4R43_35825 bafa02c33384290c28fa372acc5f960c 542 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 169 177 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A4R43_35825 bafa02c33384290c28fa372acc5f960c 542 SMART SM00490 276 357 8.8E-34 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_35825 bafa02c33384290c28fa372acc5f960c 542 Pfam PF00271 Helicase conserved C-terminal domain 248 357 1.2E-29 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_35825 bafa02c33384290c28fa372acc5f960c 542 SMART SM00487 40 240 4.0E-52 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_17710 fd013f8a5b3414763d618b289742a864 345 Pfam PF02885 Glycosyl transferase family, helical bundle domain 9 69 2.3E-21 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_17710 fd013f8a5b3414763d618b289742a864 345 Gene3D G3DSA:3.40.1030.10 76 345 4.5E-93 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_17710 fd013f8a5b3414763d618b289742a864 345 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 10 338 1.0E-110 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A4R43_17710 fd013f8a5b3414763d618b289742a864 345 Gene3D G3DSA:1.20.970.10 4 69 2.7E-29 T 14-10-2018 A4R43_17710 fd013f8a5b3414763d618b289742a864 345 SUPERFAMILY SSF47648 5 72 8.5E-20 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_17710 fd013f8a5b3414763d618b289742a864 345 SUPERFAMILY SSF52418 78 341 5.49E-78 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_17710 fd013f8a5b3414763d618b289742a864 345 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 8 340 33.825 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A4R43_17710 fd013f8a5b3414763d618b289742a864 345 Pfam PF00591 Glycosyl transferase family, a/b domain 77 330 3.8E-80 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 Pfam PF02913 FAD linked oxidases, C-terminal domain 268 519 9.4E-50 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 Gene3D G3DSA:1.10.45.10 480 520 1.7E-6 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 Pfam PF13183 4Fe-4S dicluster domain 558 635 3.8E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 SUPERFAMILY SSF56176 17 269 5.14E-55 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 SUPERFAMILY SSF46548 496 638 3.19E-9 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 SUPERFAMILY SSF55103 246 524 4.74E-51 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 Gene3D G3DSA:3.30.465.40 16 198 1.1E-47 T 14-10-2018 A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 Pfam PF02754 Cysteine-rich domain 739 813 0.08 T 14-10-2018 IPR004017 Cysteine-rich domain A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 Pfam PF02754 Cysteine-rich domain 862 937 0.041 T 14-10-2018 IPR004017 Cysteine-rich domain A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 621 632 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_03460 e27c9fbccc8013d6766ea54c08d915a6 967 Pfam PF01565 FAD binding domain 44 181 6.3E-42 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_22940 f34c1a8b5cd9e2fa32e0a3a92addb7e1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22940 f34c1a8b5cd9e2fa32e0a3a92addb7e1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22940 f34c1a8b5cd9e2fa32e0a3a92addb7e1 195 SUPERFAMILY SSF48498 88 192 6.58E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_22940 f34c1a8b5cd9e2fa32e0a3a92addb7e1 195 Gene3D G3DSA:1.10.357.10 58 195 3.2E-30 T 14-10-2018 A4R43_22940 f34c1a8b5cd9e2fa32e0a3a92addb7e1 195 SUPERFAMILY SSF46689 12 76 6.62E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22940 f34c1a8b5cd9e2fa32e0a3a92addb7e1 195 Gene3D G3DSA:1.10.10.60 14 56 4.0E-23 T 14-10-2018 A4R43_22940 f34c1a8b5cd9e2fa32e0a3a92addb7e1 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 5.6E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_02425 ae8948a40d4f326359978681acf91aba 308 SUPERFAMILY SSF51445 12 306 2.74E-63 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_02425 ae8948a40d4f326359978681acf91aba 308 Gene3D G3DSA:3.20.20.80 7 308 1.1E-91 T 14-10-2018 A4R43_02425 ae8948a40d4f326359978681acf91aba 308 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 34 284 3.3E-46 T 14-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 119 7.3E-25 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 SMART SM01008 12 120 2.7E-38 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 Gene3D G3DSA:3.30.365.10 355 717 4.3E-96 T 14-10-2018 A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 Gene3D G3DSA:3.30.365.10 10 271 1.2E-77 T 14-10-2018 A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 Gene3D G3DSA:3.90.1170.50 27 120 1.2E-77 T 14-10-2018 A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 662 1.2E-111 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 Gene3D G3DSA:3.30.365.10 426 577 4.3E-96 T 14-10-2018 A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 SUPERFAMILY SSF56003 112 719 2.36E-153 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 SUPERFAMILY SSF54665 3 131 3.93E-34 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4R43_03785 5d9617b29632d43e0bf9e2834c392f29 722 Gene3D G3DSA:3.30.365.10 121 343 1.2E-77 T 14-10-2018 A4R43_37860 29c87aa81d40e8f65b713577f0e943e2 350 SUPERFAMILY SSF81345 22 344 4.45E-77 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_37860 29c87aa81d40e8f65b713577f0e943e2 350 Gene3D G3DSA:1.10.3470.10 20 348 1.4E-93 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_37860 29c87aa81d40e8f65b713577f0e943e2 350 Pfam PF01032 FecCD transport family 36 344 1.8E-90 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_09535 2a736cea65fb58461ed51c7fc9eb655c 291 SUPERFAMILY SSF161098 83 273 4.19E-23 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_09535 2a736cea65fb58461ed51c7fc9eb655c 291 Gene3D G3DSA:1.10.3720.10 78 286 2.6E-22 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_09535 2a736cea65fb58461ed51c7fc9eb655c 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 285 1.7E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_08125 1700b623b19b2b6fe52d7088c115e454 356 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 52 323 1.4E-16 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_08125 1700b623b19b2b6fe52d7088c115e454 356 Gene3D G3DSA:3.40.50.1110 44 334 1.4E-48 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_08125 1700b623b19b2b6fe52d7088c115e454 356 SUPERFAMILY SSF52266 46 334 1.13E-37 T 14-10-2018 A4R43_39695 0750a615fcd17cd1e7def4a6b45553a5 155 Pfam PF04505 Interferon-induced transmembrane protein 79 142 3.5E-12 T 14-10-2018 IPR007593 CD225/Dispanin family GO:0016021 A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 Gene3D G3DSA:3.40.50.300 298 537 5.4E-54 T 14-10-2018 A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 SMART SM00382 360 527 1.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 SMART SM00382 26 242 6.5E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 Pfam PF12848 ABC transporter 239 314 2.7E-8 T 14-10-2018 IPR032781 ABC-transporter extension domain A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 SUPERFAMILY SSF52540 340 526 6.06E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 Gene3D G3DSA:3.40.50.300 8 296 1.3E-54 T 14-10-2018 A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 SUPERFAMILY SSF52540 3 239 5.63E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 Pfam PF00005 ABC transporter 353 481 6.1E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_05120 05ed6750a4b42e9775be4791b2362f22 542 Pfam PF00005 ABC transporter 18 197 1.1E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_16770 97fdc3690ca2477168f70e3a540048a1 336 Gene3D G3DSA:3.20.20.140 2 118 1.5E-5 T 14-10-2018 A4R43_16770 97fdc3690ca2477168f70e3a540048a1 336 Pfam PF01979 Amidohydrolase family 16 284 2.7E-16 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_16770 97fdc3690ca2477168f70e3a540048a1 336 SUPERFAMILY SSF51556 2 251 1.36E-34 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_16770 97fdc3690ca2477168f70e3a540048a1 336 Gene3D G3DSA:2.30.40.10 251 284 1.6E-33 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_16770 97fdc3690ca2477168f70e3a540048a1 336 SUPERFAMILY SSF51338 202 283 6.24E-5 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_16770 97fdc3690ca2477168f70e3a540048a1 336 Gene3D G3DSA:1.20.58.520 157 227 1.6E-33 T 14-10-2018 A4R43_16770 97fdc3690ca2477168f70e3a540048a1 336 Gene3D G3DSA:3.30.110.90 228 250 1.6E-33 T 14-10-2018 A4R43_05755 f29e8cc10da2887325535617174acaf0 253 PIRSF PIRSF001060 6 253 7.0E-83 T 14-10-2018 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A4R43_05755 f29e8cc10da2887325535617174acaf0 253 Pfam PF00182 Chitinase class I 51 253 4.8E-43 T 14-10-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A4R43_05755 f29e8cc10da2887325535617174acaf0 253 Gene3D G3DSA:1.10.530.10 53 253 1.6E-84 T 14-10-2018 A4R43_05755 f29e8cc10da2887325535617174acaf0 253 Gene3D G3DSA:3.30.20.10 114 174 1.6E-84 T 14-10-2018 A4R43_05755 f29e8cc10da2887325535617174acaf0 253 SUPERFAMILY SSF53955 50 253 2.59E-67 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_11430 1a614d9712d52f418a880681412e07e5 133 Gene3D G3DSA:3.90.1010.20 78 133 2.3E-5 T 14-10-2018 A4R43_11430 1a614d9712d52f418a880681412e07e5 133 Pfam PF04205 FMN-binding domain 58 128 7.8E-10 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 A4R43_11430 1a614d9712d52f418a880681412e07e5 133 SMART SM00900 58 131 1.1E-12 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 A4R43_01375 dec7f5342ef4d09d34fc23bb59d86528 252 Pfam PF12833 Helix-turn-helix domain 169 241 2.5E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_01375 dec7f5342ef4d09d34fc23bb59d86528 252 SUPERFAMILY SSF51182 14 166 1.03E-19 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_01375 dec7f5342ef4d09d34fc23bb59d86528 252 Gene3D G3DSA:2.60.120.10 3 81 1.9E-10 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_01375 dec7f5342ef4d09d34fc23bb59d86528 252 SMART SM00342 161 243 1.8E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_01375 dec7f5342ef4d09d34fc23bb59d86528 252 Pfam PF07883 Cupin domain 14 78 1.7E-7 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_01375 dec7f5342ef4d09d34fc23bb59d86528 252 Gene3D G3DSA:1.10.10.60 141 248 5.6E-23 T 14-10-2018 A4R43_01375 dec7f5342ef4d09d34fc23bb59d86528 252 SUPERFAMILY SSF46689 197 244 3.94E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 SUPERFAMILY SSF53732 3 606 6.15E-206 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 354 368 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 185 198 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 199 214 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 261 274 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 472 485 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 132 145 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 156 164 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 275 288 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 PRINTS PR00415 Aconitase family signature 410 421 3.6E-40 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 Gene3D G3DSA:1.10.1440.20 571 631 2.7E-18 T 14-10-2018 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 SUPERFAMILY SSF52016 610 867 3.92E-78 T 14-10-2018 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 ProSitePatterns PS01244 Aconitase family signature 2. 472 485 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 Pfam PF00694 Aconitase C-terminal domain 677 796 1.2E-38 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 Gene3D G3DSA:3.30.499.20 3 354 2.1E-141 T 14-10-2018 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 Gene3D G3DSA:3.20.19.10 634 868 5.3E-92 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 Gene3D G3DSA:3.30.499.10 355 569 6.6E-88 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 Pfam PF00330 Aconitase family (aconitate hydratase) 65 541 3.7E-164 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 25 867 0.0 T 14-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 A4R43_02065 71c7a023a311533c32f4fb28a7cf063c 874 ProSitePatterns PS00450 Aconitase family signature 1. 406 422 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4R43_36095 1fe4aa062b84c0483fd4a7dddba8478f 161 SUPERFAMILY SSF52540 2 160 1.01E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_36095 1fe4aa062b84c0483fd4a7dddba8478f 161 Pfam PF01202 Shikimate kinase 10 160 4.3E-14 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4R43_36095 1fe4aa062b84c0483fd4a7dddba8478f 161 Gene3D G3DSA:3.40.50.300 1 161 2.0E-64 T 14-10-2018 A4R43_36095 1fe4aa062b84c0483fd4a7dddba8478f 161 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 4 158 1.2E-55 T 14-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 SUPERFAMILY SSF47644 636 719 2.09E-24 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 SUPERFAMILY SSF82282 7 382 5.49E-105 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Gene3D G3DSA:3.20.20.20 329 625 3.3E-99 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Gene3D G3DSA:1.10.288.10 924 984 2.5E-45 T 14-10-2018 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Pfam PF02574 Homocysteine S-methyltransferase 18 308 5.1E-60 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 PIRSF PIRSF000381 2 1186 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 SMART SM01018 638 720 5.3E-40 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 972 1185 3.1E-30 T 14-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Gene3D G3DSA:1.10.1240.10 630 717 1.5E-29 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Gene3D G3DSA:3.10.196.10 908 1185 2.5E-45 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 SUPERFAMILY SSF56507 899 1186 1.07E-83 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Pfam PF02607 B12 binding domain 641 713 2.5E-23 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Gene3D G3DSA:3.40.50.280 723 875 7.3E-43 T 14-10-2018 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 SUPERFAMILY SSF51717 340 611 8.37E-77 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 TIGRFAM TIGR02082 metH: methionine synthase 14 1185 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Pfam PF02310 B12 binding domain 726 844 1.6E-19 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Pfam PF00809 Pterin binding enzyme 343 579 2.0E-44 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 Gene3D G3DSA:3.20.20.330 3 320 4.3E-90 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A4R43_10880 2575c1a12ae826888acc22997bce0e14 1186 SUPERFAMILY SSF52242 720 861 7.46E-40 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 Gene3D G3DSA:3.20.20.300 3 282 2.8E-102 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 Pfam PF14310 Fibronectin type III-like domain 566 636 4.5E-25 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 40 279 4.1E-51 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 28 44 3.8E-31 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 141 157 3.8E-31 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 211 229 3.8E-31 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 64 83 3.8E-31 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 110 126 3.8E-31 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 SMART SM01217 566 636 4.1E-30 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 SUPERFAMILY SSF51445 5 306 1.79E-87 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 308 532 6.8E-55 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 SUPERFAMILY SSF52279 308 535 7.59E-53 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 Gene3D G3DSA:2.60.40.10 537 650 5.6E-33 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_24290 8309a1ba16015ee7fb97a1d810e3f510 739 Gene3D G3DSA:3.40.50.1700 293 533 2.9E-74 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_13440 338c2e644106d5b02b01a2bf7fe379a6 543 Gene3D G3DSA:3.10.310.70 76 199 1.7E-125 T 14-10-2018 A4R43_13440 338c2e644106d5b02b01a2bf7fe379a6 543 Pfam PF07969 Amidohydrolase family 45 540 7.7E-94 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_13440 338c2e644106d5b02b01a2bf7fe379a6 543 SUPERFAMILY SSF51338 3 541 1.75E-22 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_13440 338c2e644106d5b02b01a2bf7fe379a6 543 Gene3D G3DSA:3.20.20.140 57 499 1.7E-125 T 14-10-2018 A4R43_13440 338c2e644106d5b02b01a2bf7fe379a6 543 SUPERFAMILY SSF51556 56 500 4.74E-37 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_13440 338c2e644106d5b02b01a2bf7fe379a6 543 Gene3D G3DSA:2.30.40.10 9 517 1.7E-125 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_37980 4b28975a817538e18b06f1586c8e9389 252 Gene3D G3DSA:1.20.58.480 1 252 1.4E-92 T 14-10-2018 A4R43_37980 4b28975a817538e18b06f1586c8e9389 252 Pfam PF03301 Tryptophan 2,3-dioxygenase 2 124 2.2E-40 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A4R43_37980 4b28975a817538e18b06f1586c8e9389 252 Pfam PF03301 Tryptophan 2,3-dioxygenase 179 251 3.7E-20 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A4R43_37980 4b28975a817538e18b06f1586c8e9389 252 SUPERFAMILY SSF140959 2 251 1.7E-80 T 14-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A4R43_37980 4b28975a817538e18b06f1586c8e9389 252 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 1 252 34.885 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A4R43_20165 777f005ac0fc7bd2f6755635c8b077db 486 Pfam PF03065 Glycosyl hydrolase family 57 10 339 1.2E-20 T 14-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A4R43_20165 777f005ac0fc7bd2f6755635c8b077db 486 Gene3D G3DSA:1.20.1430.10 391 485 1.4E-12 T 14-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A4R43_20165 777f005ac0fc7bd2f6755635c8b077db 486 SUPERFAMILY SSF88688 384 484 7.19E-17 T 14-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A4R43_20165 777f005ac0fc7bd2f6755635c8b077db 486 Gene3D G3DSA:3.20.110.10 3 389 1.1E-108 T 14-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily A4R43_20165 777f005ac0fc7bd2f6755635c8b077db 486 SUPERFAMILY SSF88713 6 389 1.6E-94 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4R43_20165 777f005ac0fc7bd2f6755635c8b077db 486 Pfam PF09210 Domain of unknown function (DUF1957) 412 469 5.6E-16 T 14-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 SMART SM00344 2 107 3.5E-12 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 SMART SM00344 180 283 1.5E-4 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 Gene3D G3DSA:1.10.10.10 1 49 7.7E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 Gene3D G3DSA:1.10.10.10 179 225 1.8E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 4.5E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 4.5E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 9.7E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 Gene3D G3DSA:3.30.70.920 229 320 2.1E-8 T 14-10-2018 A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 Gene3D G3DSA:3.30.70.920 53 144 1.5E-8 T 14-10-2018 A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 SUPERFAMILY SSF54909 237 316 3.93E-5 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 SUPERFAMILY SSF54909 65 138 2.82E-7 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_13380 a2919ed3076ecd4f4be3dd13d9934850 324 SUPERFAMILY SSF46785 2 49 6.55E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 SUPERFAMILY SSF48452 494 682 7.71E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 PRINTS PR00364 Disease resistance protein signature 240 254 8.2E-9 T 14-10-2018 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 PRINTS PR00364 Disease resistance protein signature 73 88 8.2E-9 T 14-10-2018 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 PRINTS PR00364 Disease resistance protein signature 152 166 8.2E-9 T 14-10-2018 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 Pfam PF00931 NB-ARC domain 75 309 8.8E-9 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 SUPERFAMILY SSF52540 35 305 4.16E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 Gene3D G3DSA:3.40.50.300 34 198 1.0E-25 T 14-10-2018 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 Pfam PF13424 Tetratricopeptide repeat 495 564 9.7E-10 T 14-10-2018 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 Pfam PF13424 Tetratricopeptide repeat 615 685 3.7E-11 T 14-10-2018 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 Gene3D G3DSA:1.25.40.10 443 569 2.9E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 Gene3D G3DSA:1.25.40.10 570 704 5.0E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 SMART SM00028 493 526 0.16 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 SMART SM00028 613 646 2.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 SMART SM00028 653 686 25.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 SMART SM00028 533 566 0.45 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_04270 1c3d7b5f045eb6076d455fc2e9b3b1c1 705 SMART SM00028 573 606 0.012 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_36490 7704ab3bb1cc1142f70772c2a17ebaa1 232 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 230 1.0E-18 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_36490 7704ab3bb1cc1142f70772c2a17ebaa1 232 SUPERFAMILY SSF46689 16 79 3.33E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_36490 7704ab3bb1cc1142f70772c2a17ebaa1 232 Gene3D G3DSA:1.10.10.60 2 76 9.6E-21 T 14-10-2018 A4R43_36490 7704ab3bb1cc1142f70772c2a17ebaa1 232 SUPERFAMILY SSF48498 86 230 3.56E-24 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_36490 7704ab3bb1cc1142f70772c2a17ebaa1 232 Gene3D G3DSA:1.10.357.10 79 231 4.1E-33 T 14-10-2018 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 SUPERFAMILY SSF50249 38 211 1.2E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Gene3D G3DSA:3.30.56.10 422 498 7.9E-14 T 14-10-2018 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Gene3D G3DSA:3.50.40.10 218 413 1.2E-73 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Gene3D G3DSA:3.30.56.10 7 198 6.6E-53 T 14-10-2018 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 SUPERFAMILY SSF46955 423 498 1.56E-12 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Pfam PF03484 tRNA synthetase B5 domain 427 494 8.8E-12 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Gene3D G3DSA:3.30.930.10 509 736 1.2E-55 T 14-10-2018 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Pfam PF03483 B3/4 domain 233 404 6.4E-65 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Gene3D G3DSA:3.30.70.380 748 841 6.9E-25 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 SMART SM00896 747 840 9.8E-40 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 834 39.447 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Pfam PF03147 Ferredoxin-fold anticodon binding domain 747 840 6.5E-23 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 2 840 7.0E-171 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Gene3D G3DSA:2.40.50.140 41 173 6.6E-53 T 14-10-2018 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 SUPERFAMILY SSF54991 745 840 2.48E-25 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 SUPERFAMILY SSF55681 490 736 2.83E-41 T 14-10-2018 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 SMART SM00874 421 494 5.9E-17 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 SMART SM00873 232 405 1.2E-82 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 Pfam PF01588 Putative tRNA binding domain 47 163 1.4E-14 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A4R43_14345 5505002e262b3f6cc5a71144e701dbca 841 SUPERFAMILY SSF56037 218 415 2.12E-66 T 14-10-2018 A4R43_33450 9bfa600851aa19f66d00ebfbb8aac61a 460 Gene3D G3DSA:1.10.510.10 130 332 2.2E-5 T 14-10-2018 A4R43_33450 9bfa600851aa19f66d00ebfbb8aac61a 460 SUPERFAMILY SSF56112 100 313 2.78E-18 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_33450 9bfa600851aa19f66d00ebfbb8aac61a 460 Pfam PF03109 ABC1 family 117 230 1.1E-32 T 14-10-2018 IPR004147 UbiB domain A4R43_24800 09c2aab028b1fe9a67d664bf87512fca 226 Pfam PF13500 AAA domain 8 176 4.8E-16 T 14-10-2018 A4R43_24800 09c2aab028b1fe9a67d664bf87512fca 226 SUPERFAMILY SSF52540 7 198 1.62E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24800 09c2aab028b1fe9a67d664bf87512fca 226 Gene3D G3DSA:3.40.50.300 5 209 5.0E-31 T 14-10-2018 A4R43_24480 45e68d7512643369a5670617118e27e2 111 SUPERFAMILY SSF46785 4 90 1.24E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_24480 45e68d7512643369a5670617118e27e2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.4E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_24480 45e68d7512643369a5670617118e27e2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.4E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_24480 45e68d7512643369a5670617118e27e2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.4E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_24480 45e68d7512643369a5670617118e27e2 111 SMART SM00418 11 89 1.1E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_24480 45e68d7512643369a5670617118e27e2 111 Gene3D G3DSA:1.10.10.10 3 104 2.9E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_24480 45e68d7512643369a5670617118e27e2 111 Pfam PF12840 Helix-turn-helix domain 11 68 3.4E-12 T 14-10-2018 A4R43_22815 f0cdf4458dbc8aaff8d149333cd16885 167 SUPERFAMILY SSF50891 6 151 4.93E-8 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_22815 f0cdf4458dbc8aaff8d149333cd16885 167 Pfam PF12903 Protein of unknown function (DUF3830) 7 164 1.4E-64 T 14-10-2018 IPR024532 Protein of unknown function DUF3830 A4R43_22815 f0cdf4458dbc8aaff8d149333cd16885 167 Gene3D G3DSA:2.40.100.20 2 167 1.1E-61 T 14-10-2018 A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 SMART SM00345 22 80 5.4E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 Gene3D G3DSA:1.10.10.10 4 81 6.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 Pfam PF07729 FCD domain 90 209 3.2E-16 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 SMART SM00895 90 210 3.8E-11 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 4.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 4.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 Gene3D G3DSA:1.20.120.530 85 222 4.5E-19 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.1E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 SUPERFAMILY SSF48008 87 218 1.15E-17 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_04775 d1f86023c97c24ba68eb2519581f1963 224 SUPERFAMILY SSF46785 13 84 3.15E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13760 9f33fec9e69a7afa3e477a77d04b378f 534 SMART SM00220 1 248 5.5E-45 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_13760 9f33fec9e69a7afa3e477a77d04b378f 534 Gene3D G3DSA:1.10.510.10 70 253 1.9E-44 T 14-10-2018 A4R43_13760 9f33fec9e69a7afa3e477a77d04b378f 534 SUPERFAMILY SSF56112 1 246 1.75E-61 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_13760 9f33fec9e69a7afa3e477a77d04b378f 534 Gene3D G3DSA:3.30.200.20 1 69 4.8E-17 T 14-10-2018 A4R43_13760 9f33fec9e69a7afa3e477a77d04b378f 534 Pfam PF00069 Protein kinase domain 2 242 2.9E-42 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_13760 9f33fec9e69a7afa3e477a77d04b378f 534 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 113 125 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_07185 272c2c12d28f7ad85c990ff69ce1f49d 116 SUPERFAMILY SSF52833 2 115 2.31E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_07185 272c2c12d28f7ad85c990ff69ce1f49d 116 Gene3D G3DSA:3.40.30.10 1 116 4.4E-37 T 14-10-2018 A4R43_07185 272c2c12d28f7ad85c990ff69ce1f49d 116 Pfam PF03960 ArsC family 5 114 5.5E-13 T 14-10-2018 IPR006660 Arsenate reductase-like A4R43_02580 a67b7f5390cf100faabfbec6b161d071 366 Gene3D G3DSA:1.10.510.10 97 293 1.1E-36 T 14-10-2018 A4R43_02580 a67b7f5390cf100faabfbec6b161d071 366 SUPERFAMILY SSF56112 11 286 7.65E-59 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_02580 a67b7f5390cf100faabfbec6b161d071 366 Pfam PF00069 Protein kinase domain 14 266 3.5E-40 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_02580 a67b7f5390cf100faabfbec6b161d071 366 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 138 150 - T 14-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A4R43_02580 a67b7f5390cf100faabfbec6b161d071 366 Gene3D G3DSA:3.30.200.20 1 96 1.2E-17 T 14-10-2018 A4R43_19820 d7b9c7a440f19c0fde6185ea04012cf6 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 1.3E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19820 d7b9c7a440f19c0fde6185ea04012cf6 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.8E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19820 d7b9c7a440f19c0fde6185ea04012cf6 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.8E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19820 d7b9c7a440f19c0fde6185ea04012cf6 235 SUPERFAMILY SSF46689 6 82 1.07E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19820 d7b9c7a440f19c0fde6185ea04012cf6 235 Gene3D G3DSA:1.10.357.10 6 218 1.7E-22 T 14-10-2018 A4R43_33090 8cb758b346c997f17b86d0a775415db2 252 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 111 232 5.8E-45 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33090 8cb758b346c997f17b86d0a775415db2 252 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 160 221 7.0E-20 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33090 8cb758b346c997f17b86d0a775415db2 252 Gene3D G3DSA:3.30.460.80 63 212 9.2E-49 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33090 8cb758b346c997f17b86d0a775415db2 252 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 84 240 29.855 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33090 8cb758b346c997f17b86d0a775415db2 252 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 110 231 1.6E-43 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33090 8cb758b346c997f17b86d0a775415db2 252 SUPERFAMILY SSF143243 96 248 7.98E-51 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 Pfam PF02881 SRP54-type protein, helical bundle domain 193 255 1.4E-7 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 Pfam PF00448 SRP54-type protein, GTPase domain 281 480 6.9E-72 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 Gene3D G3DSA:3.40.50.300 281 468 9.6E-98 T 14-10-2018 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 203 480 57.167 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 SMART SM00382 280 430 1.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 SMART SM00963 180 260 7.1E-15 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 204 479 1.3E-102 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 SUPERFAMILY SSF52540 279 479 4.97E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 SMART SM00962 281 480 6.1E-101 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 453 466 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 Gene3D G3DSA:1.20.120.140 178 478 9.6E-98 T 14-10-2018 A4R43_18645 a4f432987be6479223c827ab24c41ac1 480 SUPERFAMILY SSF47364 175 254 1.31E-16 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A4R43_25600 0f780d658339062c0d4ca65e5ff96fbb 205 Gene3D G3DSA:1.10.10.60 3 62 4.4E-15 T 14-10-2018 A4R43_25600 0f780d658339062c0d4ca65e5ff96fbb 205 SUPERFAMILY SSF46689 11 87 5.64E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25600 0f780d658339062c0d4ca65e5ff96fbb 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 5.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25600 0f780d658339062c0d4ca65e5ff96fbb 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 5.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25600 0f780d658339062c0d4ca65e5ff96fbb 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25600 0f780d658339062c0d4ca65e5ff96fbb 205 SUPERFAMILY SSF48498 90 202 5.84E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_25600 0f780d658339062c0d4ca65e5ff96fbb 205 Gene3D G3DSA:1.10.357.10 63 204 3.5E-15 T 14-10-2018 A4R43_27975 973a3056c4674fc93bcc08b392216926 267 Pfam PF12146 Serine aminopeptidase, S33 77 182 3.5E-10 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 A4R43_27975 973a3056c4674fc93bcc08b392216926 267 Gene3D G3DSA:3.40.50.1820 49 261 3.3E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27975 973a3056c4674fc93bcc08b392216926 267 SUPERFAMILY SSF53474 19 258 5.59E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_10305 e26f9079db7b657aae474a28adfba557 339 Gene3D G3DSA:3.10.450.50 196 321 1.3E-17 T 14-10-2018 A4R43_10305 e26f9079db7b657aae474a28adfba557 339 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 31 62 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_10305 e26f9079db7b657aae474a28adfba557 339 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 188 8.8E-28 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_10305 e26f9079db7b657aae474a28adfba557 339 SUPERFAMILY SSF88946 2 81 3.14E-25 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_10305 e26f9079db7b657aae474a28adfba557 339 SUPERFAMILY SSF88659 129 188 8.41E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_10305 e26f9079db7b657aae474a28adfba557 339 Pfam PF12680 SnoaL-like domain 207 308 3.9E-9 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_10305 e26f9079db7b657aae474a28adfba557 339 Gene3D G3DSA:1.10.1740.10 1 88 1.2E-25 T 14-10-2018 A4R43_10305 e26f9079db7b657aae474a28adfba557 339 SUPERFAMILY SSF54427 199 321 5.39E-16 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_10305 e26f9079db7b657aae474a28adfba557 339 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 2 322 1.8E-121 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_10305 e26f9079db7b657aae474a28adfba557 339 Pfam PF04542 Sigma-70 region 2 10 76 2.9E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_10305 e26f9079db7b657aae474a28adfba557 339 Gene3D G3DSA:1.10.10.10 132 190 1.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10305 e26f9079db7b657aae474a28adfba557 339 Pfam PF08281 Sigma-70, region 4 133 184 1.6E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_37475 43cbfad6d7c7c417a4278dc4294f4c12 208 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 106 203 1.7E-12 T 14-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like A4R43_37475 43cbfad6d7c7c417a4278dc4294f4c12 208 Gene3D G3DSA:2.60.120.590 27 205 5.2E-38 T 14-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily A4R43_37475 43cbfad6d7c7c417a4278dc4294f4c12 208 SUPERFAMILY SSF51197 30 203 1.51E-41 T 14-10-2018 A4R43_04415 b978bb5d80c684cfa00d1affe125ea2f 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 125 6.4E-18 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_04415 b978bb5d80c684cfa00d1affe125ea2f 334 SUPERFAMILY SSF51735 6 156 2.63E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04415 b978bb5d80c684cfa00d1affe125ea2f 334 SUPERFAMILY SSF55347 130 296 2.4E-14 T 14-10-2018 A4R43_04415 b978bb5d80c684cfa00d1affe125ea2f 334 Gene3D G3DSA:3.30.360.10 136 329 1.7E-21 T 14-10-2018 A4R43_04415 b978bb5d80c684cfa00d1affe125ea2f 334 Gene3D G3DSA:3.40.50.720 5 135 4.9E-27 T 14-10-2018 A4R43_02325 a26ce3b76dc8328f89c7334654dbf3d2 64 Gene3D G3DSA:3.90.820.10 1 64 2.0E-35 T 14-10-2018 A4R43_02325 a26ce3b76dc8328f89c7334654dbf3d2 64 Pfam PF03621 MbtH-like protein 2 53 5.1E-29 T 14-10-2018 IPR005153 MbtH-like domain A4R43_02325 a26ce3b76dc8328f89c7334654dbf3d2 64 SUPERFAMILY SSF160582 2 64 9.55E-31 T 14-10-2018 IPR038020 MbtH-like domain superfamily A4R43_02325 a26ce3b76dc8328f89c7334654dbf3d2 64 SMART SM00923 3 53 8.6E-33 T 14-10-2018 IPR005153 MbtH-like domain A4R43_02805 89a25120f4d5ce059a33abf4f7ffe014 514 Gene3D G3DSA:1.20.1720.10 14 221 4.3E-40 T 14-10-2018 A4R43_02805 89a25120f4d5ce059a33abf4f7ffe014 514 SUPERFAMILY SSF103473 5 500 3.79E-61 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_02805 89a25120f4d5ce059a33abf4f7ffe014 514 Gene3D G3DSA:1.20.1250.20 272 503 3.5E-23 T 14-10-2018 A4R43_02805 89a25120f4d5ce059a33abf4f7ffe014 514 Pfam PF07690 Major Facilitator Superfamily 19 411 1.4E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_16565 55ea73ef4441cdb12fbfd3f8b4c0ab96 377 Gene3D G3DSA:3.40.50.2000 23 365 5.7E-95 T 14-10-2018 A4R43_16565 55ea73ef4441cdb12fbfd3f8b4c0ab96 377 SUPERFAMILY SSF53756 21 375 7.25E-96 T 14-10-2018 A4R43_16565 55ea73ef4441cdb12fbfd3f8b4c0ab96 377 Gene3D G3DSA:3.40.50.2000 178 359 5.7E-95 T 14-10-2018 A4R43_16565 55ea73ef4441cdb12fbfd3f8b4c0ab96 377 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 22 375 30.427 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_16565 55ea73ef4441cdb12fbfd3f8b4c0ab96 377 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 206 363 2.6E-33 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 A4R43_16565 55ea73ef4441cdb12fbfd3f8b4c0ab96 377 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 22 160 9.7E-38 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_16565 55ea73ef4441cdb12fbfd3f8b4c0ab96 377 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 21 370 6.8E-83 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_06435 90068065d1fb1e41be5e5eebf2845090 348 Pfam PF00553 Cellulose binding domain 250 344 5.1E-29 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_06435 90068065d1fb1e41be5e5eebf2845090 348 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 33 221 1.3E-39 T 14-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal A4R43_06435 90068065d1fb1e41be5e5eebf2845090 348 Gene3D G3DSA:2.60.40.290 245 347 2.7E-30 T 14-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A4R43_06435 90068065d1fb1e41be5e5eebf2845090 348 Gene3D G3DSA:2.70.50.50 33 226 8.3E-63 T 14-10-2018 A4R43_06435 90068065d1fb1e41be5e5eebf2845090 348 SMART SM00637 250 345 9.8E-36 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_06435 90068065d1fb1e41be5e5eebf2845090 348 SUPERFAMILY SSF81296 33 225 1.68E-43 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_06435 90068065d1fb1e41be5e5eebf2845090 348 SUPERFAMILY SSF49384 245 343 5.23E-30 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 322 397 4.5E-17 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 SUPERFAMILY SSF53244 321 459 2.75E-32 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 SUPERFAMILY SSF53623 102 316 3.66E-49 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 Gene3D G3DSA:3.40.1390.10 1 83 1.9E-16 T 14-10-2018 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 Gene3D G3DSA:3.40.1190.10 84 316 1.1E-66 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 Gene3D G3DSA:3.90.190.20 320 462 2.7E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 Pfam PF08245 Mur ligase middle domain 107 299 3.3E-36 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 SUPERFAMILY SSF63418 4 98 2.75E-17 T 14-10-2018 IPR035911 MurE/MurF, N-terminal A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 459 5.7E-117 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 460 29.552 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_24750 8d9ec3de300222eae3719e74aa3cb35b 462 Pfam PF01225 Mur ligase family, catalytic domain 32 94 3.9E-7 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4R43_37910 723a76d139bdf7a0dfa365a71ca53eba 326 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 34 324 1.9E-91 T 14-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4R43_37910 723a76d139bdf7a0dfa365a71ca53eba 326 Pfam PF01008 Initiation factor 2 subunit family 48 324 6.1E-63 T 14-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A4R43_37910 723a76d139bdf7a0dfa365a71ca53eba 326 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 5 325 34.194 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4R43_37910 723a76d139bdf7a0dfa365a71ca53eba 326 Gene3D G3DSA:3.40.50.10470 178 325 2.7E-50 T 14-10-2018 A4R43_37910 723a76d139bdf7a0dfa365a71ca53eba 326 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 7 324 6.1E-113 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4R43_37910 723a76d139bdf7a0dfa365a71ca53eba 326 Gene3D G3DSA:1.20.120.1840 5 177 7.9E-44 T 14-10-2018 A4R43_37910 723a76d139bdf7a0dfa365a71ca53eba 326 SUPERFAMILY SSF100950 7 324 3.98E-100 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_36505 608dad20bd5adda986d086e8a7ca0ac5 1163 Gene3D G3DSA:3.20.20.140 1 281 3.1E-87 T 14-10-2018 A4R43_36505 608dad20bd5adda986d086e8a7ca0ac5 1163 SMART SM00481 1 58 3.5E-18 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A4R43_36505 608dad20bd5adda986d086e8a7ca0ac5 1163 Pfam PF14579 Helix-hairpin-helix motif 820 906 5.4E-26 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_36505 608dad20bd5adda986d086e8a7ca0ac5 1163 Gene3D G3DSA:1.10.10.1600 439 528 4.8E-15 T 14-10-2018 A4R43_36505 608dad20bd5adda986d086e8a7ca0ac5 1163 Pfam PF02811 PHP domain 1 184 2.6E-43 T 14-10-2018 IPR004013 PHP domain GO:0003824 A4R43_36505 608dad20bd5adda986d086e8a7ca0ac5 1163 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 306 747 1.8E-156 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_36505 608dad20bd5adda986d086e8a7ca0ac5 1163 SUPERFAMILY SSF89550 3 260 5.1E-23 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4R43_36505 608dad20bd5adda986d086e8a7ca0ac5 1163 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 1 1043 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SUPERFAMILY SSF48452 761 899 1.14E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SMART SM00862 18 96 5.6E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SUPERFAMILY SSF52540 271 531 6.41E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Gene3D G3DSA:3.40.50.300 269 422 1.5E-24 T 14-10-2018 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 PRINTS PR00364 Disease resistance protein signature 299 314 1.2E-7 T 14-10-2018 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 PRINTS PR00364 Disease resistance protein signature 378 392 1.2E-7 T 14-10-2018 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 PRINTS PR00364 Disease resistance protein signature 463 477 1.2E-7 T 14-10-2018 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Gene3D G3DSA:1.25.40.10 102 268 2.4E-42 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SMART SM01043 103 247 3.9E-43 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SMART SM00028 868 901 50.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SMART SM00028 828 861 98.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SMART SM00028 108 141 77.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SMART SM00028 748 781 150.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SMART SM00028 788 821 6.1 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SMART SM00028 708 741 28.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SUPERFAMILY SSF48452 677 786 3.48E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Pfam PF13424 Tetratricopeptide repeat 831 895 3.7E-7 T 14-10-2018 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Pfam PF03704 Bacterial transcriptional activator domain 103 247 7.5E-36 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SUPERFAMILY SSF46894 5 96 1.28E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Gene3D G3DSA:1.10.10.10 2 98 1.9E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 96 5.1E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 SUPERFAMILY SSF48452 99 257 6.56E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Gene3D G3DSA:1.25.40.10 825 909 4.0E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Gene3D G3DSA:1.25.40.10 676 824 1.0E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_09860 8acc5db458ab08eae52ea692964b72aa 935 Pfam PF00931 NB-ARC domain 295 534 2.7E-12 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 Pfam PF00072 Response regulator receiver domain 4 118 1.5E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 7.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 7.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 7.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 SUPERFAMILY SSF52172 1 132 7.4E-31 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 7.2E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 SMART SM00421 152 209 1.4E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 SUPERFAMILY SSF46894 146 215 1.22E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 SMART SM00448 2 117 1.2E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30910 4919b4a38fc2d515e67ec54f1635ad1b 217 Gene3D G3DSA:3.40.50.12740 2 215 6.8E-65 T 14-10-2018 A4R43_31310 893822f4c3cccf44cb76aa83b8c0001e 535 SUPERFAMILY SSF56645 57 289 4.06E-42 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_31310 893822f4c3cccf44cb76aa83b8c0001e 535 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 390 409 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_31310 893822f4c3cccf44cb76aa83b8c0001e 535 Gene3D G3DSA:2.40.110.20 127 279 8.4E-57 T 14-10-2018 A4R43_31310 893822f4c3cccf44cb76aa83b8c0001e 535 Gene3D G3DSA:1.20.140.10 280 433 1.4E-31 T 14-10-2018 A4R43_31310 893822f4c3cccf44cb76aa83b8c0001e 535 SUPERFAMILY SSF47203 285 435 1.14E-35 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_31310 893822f4c3cccf44cb76aa83b8c0001e 535 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 177 270 1.8E-16 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_31310 893822f4c3cccf44cb76aa83b8c0001e 535 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 431 9.6E-27 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_33210 d7a9fac05fe76e4393abb30411be2e7d 430 Gene3D G3DSA:1.20.1260.20 9 168 1.2E-5 T 14-10-2018 IPR038332 PPE superfamily A4R43_33210 d7a9fac05fe76e4393abb30411be2e7d 430 SUPERFAMILY SSF140459 12 157 2.01E-6 T 14-10-2018 A4R43_41545 9a8d00c81865382e54f42b4463770519 204 PIRSF PIRSF015617 3 204 3.5E-63 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A4R43_41545 9a8d00c81865382e54f42b4463770519 204 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 204 1.8E-58 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A4R43_41545 9a8d00c81865382e54f42b4463770519 204 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 204 2.1E-73 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A4R43_41545 9a8d00c81865382e54f42b4463770519 204 Gene3D G3DSA:3.40.50.300 9 204 1.8E-60 T 14-10-2018 A4R43_41545 9a8d00c81865382e54f42b4463770519 204 SUPERFAMILY SSF52540 12 204 1.59E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26485 29c7b31ce6ec0129036537a558b589c0 203 Pfam PF07510 Protein of unknown function (DUF1524) 98 198 4.0E-9 T 14-10-2018 IPR011089 Domain of unknown function DUF1524 A4R43_35075 5f30ddc41b7601728d54be77e13a1715 385 SUPERFAMILY SSF56645 5 205 3.66E-36 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_35075 5f30ddc41b7601728d54be77e13a1715 385 Gene3D G3DSA:2.40.110.10 109 207 1.7E-23 T 14-10-2018 A4R43_35075 5f30ddc41b7601728d54be77e13a1715 385 PIRSF PIRSF016578 2 378 7.1E-36 T 14-10-2018 A4R43_35075 5f30ddc41b7601728d54be77e13a1715 385 Gene3D G3DSA:1.10.540.10 2 108 4.0E-22 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_35075 5f30ddc41b7601728d54be77e13a1715 385 Gene3D G3DSA:1.20.140.10 214 385 1.9E-52 T 14-10-2018 A4R43_35075 5f30ddc41b7601728d54be77e13a1715 385 SUPERFAMILY SSF47203 226 380 1.93E-20 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_35075 5f30ddc41b7601728d54be77e13a1715 385 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 228 360 7.8E-19 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4R43_35075 5f30ddc41b7601728d54be77e13a1715 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 81 1.8E-5 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_26885 0d9f33a19ea57f22acbf55fd907b249f 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_26885 0d9f33a19ea57f22acbf55fd907b249f 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 1.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_26885 0d9f33a19ea57f22acbf55fd907b249f 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_26885 0d9f33a19ea57f22acbf55fd907b249f 106 Pfam PF12840 Helix-turn-helix domain 20 78 2.4E-12 T 14-10-2018 A4R43_26885 0d9f33a19ea57f22acbf55fd907b249f 106 SUPERFAMILY SSF46785 7 98 3.25E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26885 0d9f33a19ea57f22acbf55fd907b249f 106 Gene3D G3DSA:1.10.10.10 6 106 3.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26885 0d9f33a19ea57f22acbf55fd907b249f 106 SMART SM00418 21 98 1.0E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_13220 8d59b5d3deaa1d6523abf1b9692e5474 798 Pfam PF08376 Nitrate and nitrite sensing 67 305 1.9E-31 T 14-10-2018 IPR013587 Nitrate/nitrite sensing protein A4R43_13220 8d59b5d3deaa1d6523abf1b9692e5474 798 Pfam PF00672 HAMP domain 349 414 1.3E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13220 8d59b5d3deaa1d6523abf1b9692e5474 798 SUPERFAMILY SSF55874 517 642 2.05E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_13220 8d59b5d3deaa1d6523abf1b9692e5474 798 Gene3D G3DSA:3.30.565.10 496 644 6.5E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_13220 8d59b5d3deaa1d6523abf1b9692e5474 798 SMART SM00387 531 643 0.0021 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_40855 a2423c679f1a45c433db60cf2650a373 436 Gene3D G3DSA:2.120.10.30 147 373 7.3E-21 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_40855 a2423c679f1a45c433db60cf2650a373 436 SUPERFAMILY SSF50952 62 435 5.49E-33 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_40855 a2423c679f1a45c433db60cf2650a373 436 Pfam PF07995 Glucose / Sorbosone dehydrogenase 193 359 4.7E-16 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_41380 f7e66d6f215df3316c6db32a7af5e536 363 Gene3D G3DSA:3.40.50.300 40 237 2.9E-44 T 14-10-2018 A4R43_41380 f7e66d6f215df3316c6db32a7af5e536 363 PIRSF PIRSF002849 17 353 2.3E-129 T 14-10-2018 A4R43_41380 f7e66d6f215df3316c6db32a7af5e536 363 SUPERFAMILY SSF52540 51 323 2.82E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41380 f7e66d6f215df3316c6db32a7af5e536 363 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 79 208 1.4E-62 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A4R43_41380 f7e66d6f215df3316c6db32a7af5e536 363 Gene3D G3DSA:1.10.8.300 240 348 1.1E-30 T 14-10-2018 A4R43_41325 8d9b9e0a1461a4e4c2e0aa99365671c4 420 Gene3D G3DSA:3.90.1300.10 204 293 6.5E-6 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_41325 8d9b9e0a1461a4e4c2e0aa99365671c4 420 Gene3D G3DSA:3.90.1300.10 14 117 3.9E-7 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_41325 8d9b9e0a1461a4e4c2e0aa99365671c4 420 Gene3D G3DSA:3.10.490.10 294 418 5.9E-24 T 14-10-2018 A4R43_41325 8d9b9e0a1461a4e4c2e0aa99365671c4 420 SUPERFAMILY SSF75304 20 284 1.31E-10 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_23150 ea136b78d0807f58301ea767f9b11f2c 159 SUPERFAMILY SSF55826 6 156 1.24E-42 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4R43_23150 ea136b78d0807f58301ea767f9b11f2c 159 PIRSF PIRSF006181 1 159 1.2E-51 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A4R43_23150 ea136b78d0807f58301ea767f9b11f2c 159 Pfam PF04073 Aminoacyl-tRNA editing domain 36 148 8.7E-26 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4R43_23150 ea136b78d0807f58301ea767f9b11f2c 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 157 4.9E-54 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A4R43_23150 ea136b78d0807f58301ea767f9b11f2c 159 Gene3D G3DSA:3.90.960.10 2 158 9.8E-59 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4R43_15005 20a4a400ef86d3ecbd411fd777736a22 124 SUPERFAMILY SSF141571 2 110 4.32E-13 T 14-10-2018 A4R43_15005 20a4a400ef86d3ecbd411fd777736a22 124 Pfam PF00805 Pentapeptide repeats (8 copies) 66 91 1.5E-4 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_15005 20a4a400ef86d3ecbd411fd777736a22 124 Gene3D G3DSA:2.160.20.100 1 117 3.5E-15 T 14-10-2018 A4R43_07110 090b0c2d13b2c26e8f38f406fb10d3f8 602 Gene3D G3DSA:3.40.50.12780 4 300 1.4E-54 T 14-10-2018 A4R43_07110 090b0c2d13b2c26e8f38f406fb10d3f8 602 Pfam PF00501 AMP-binding enzyme 19 471 2.6E-94 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_07110 090b0c2d13b2c26e8f38f406fb10d3f8 602 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_07110 090b0c2d13b2c26e8f38f406fb10d3f8 602 SUPERFAMILY SSF56801 16 597 8.11E-118 T 14-10-2018 A4R43_07110 090b0c2d13b2c26e8f38f406fb10d3f8 602 Gene3D G3DSA:3.40.50.12780 325 467 3.6E-39 T 14-10-2018 A4R43_05905 8eb3a9d05b8f795776ec62880caed743 260 Pfam PF09339 IclR helix-turn-helix domain 13 62 4.5E-17 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_05905 8eb3a9d05b8f795776ec62880caed743 260 Pfam PF01614 Bacterial transcriptional regulator 127 242 1.5E-32 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_05905 8eb3a9d05b8f795776ec62880caed743 260 Gene3D G3DSA:1.10.10.10 6 78 2.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05905 8eb3a9d05b8f795776ec62880caed743 260 SUPERFAMILY SSF46785 12 80 1.41E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05905 8eb3a9d05b8f795776ec62880caed743 260 SMART SM00346 10 99 5.0E-22 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_05905 8eb3a9d05b8f795776ec62880caed743 260 SUPERFAMILY SSF55781 74 249 8.5E-45 T 14-10-2018 A4R43_05905 8eb3a9d05b8f795776ec62880caed743 260 Gene3D G3DSA:3.30.450.40 79 253 5.1E-49 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 PIRSF PIRSF000124 1 409 1.9E-115 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 298 393 1.4E-26 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 Gene3D G3DSA:1.20.5.100 182 211 2.4E-14 T 14-10-2018 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 182 272 1.3E-33 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 161 1.1E-45 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 SUPERFAMILY SSF51735 1 171 1.19E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 Gene3D G3DSA:3.40.50.720 1 181 2.7E-57 T 14-10-2018 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 SUPERFAMILY SSF48179 182 279 7.74E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 SMART SM00984 297 394 1.1E-37 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 390 1.3E-118 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 Gene3D G3DSA:3.40.50.720 212 420 9.3E-68 T 14-10-2018 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 SUPERFAMILY SSF52413 286 402 1.57E-32 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A4R43_28835 728711ec39f13cb1a383b9ad4ae7ad86 421 PIRSF PIRSF500134 1 412 7.7E-143 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A4R43_29860 d87e4bd1b59037701a5dff186204e125 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 54 4.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_29860 d87e4bd1b59037701a5dff186204e125 196 SUPERFAMILY SSF46689 2 69 2.41E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_29860 d87e4bd1b59037701a5dff186204e125 196 Gene3D G3DSA:1.10.357.10 1 179 1.6E-26 T 14-10-2018 A4R43_41530 f2c7cb338b4005889113585a135658ce 253 SUPERFAMILY SSF53790 2 231 1.57E-59 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4R43_41530 f2c7cb338b4005889113585a135658ce 253 Gene3D G3DSA:3.30.950.10 111 231 3.4E-39 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4R43_41530 f2c7cb338b4005889113585a135658ce 253 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4R43_41530 f2c7cb338b4005889113585a135658ce 253 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 243 2.0E-83 T 14-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 A4R43_41530 f2c7cb338b4005889113585a135658ce 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 208 5.1E-41 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4R43_41530 f2c7cb338b4005889113585a135658ce 253 Gene3D G3DSA:3.40.1010.10 1 110 1.4E-28 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 Pfam PF08281 Sigma-70, region 4 137 187 3.2E-11 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 21 323 5.7E-90 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 Pfam PF04542 Sigma-70 region 2 31 95 3.3E-18 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 SUPERFAMILY SSF88659 133 192 6.73E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 SUPERFAMILY SSF88946 13 107 1.53E-25 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 Gene3D G3DSA:1.10.10.10 118 193 1.3E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 192 6.2E-23 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 SUPERFAMILY SSF54427 209 317 1.88E-7 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 Gene3D G3DSA:3.10.450.50 205 328 5.8E-10 T 14-10-2018 A4R43_09360 814c85eefdc8816eef4d24274f406be9 333 Gene3D G3DSA:1.10.1740.10 8 110 5.8E-28 T 14-10-2018 A4R43_23600 ce306282edbfe229b2ff6e566a8066e9 205 SMART SM00849 24 188 3.7E-38 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_23600 ce306282edbfe229b2ff6e566a8066e9 205 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 1.8E-24 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_23600 ce306282edbfe229b2ff6e566a8066e9 205 SUPERFAMILY SSF56281 9 200 2.17E-48 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_23600 ce306282edbfe229b2ff6e566a8066e9 205 Gene3D G3DSA:3.60.15.10 20 203 2.9E-51 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_31820 6d57764582696962d025a0f077d344ae 314 Gene3D G3DSA:1.10.10.10 241 312 1.2E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31820 6d57764582696962d025a0f077d344ae 314 SUPERFAMILY SSF46785 238 306 3.66E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31820 6d57764582696962d025a0f077d344ae 314 Pfam PF12840 Helix-turn-helix domain 248 298 2.5E-8 T 14-10-2018 A4R43_31820 6d57764582696962d025a0f077d344ae 314 SMART SM00418 242 313 0.0017 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 SUPERFAMILY SSF54909 68 142 1.47E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 SMART SM00344 7 113 4.5E-38 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 8.4E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 8.4E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 8.4E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 54 2.6E-16 T 14-10-2018 A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 SUPERFAMILY SSF46785 6 66 4.85E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 Pfam PF01037 Lrp/AsnC ligand binding domain 73 139 1.9E-14 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 Gene3D G3DSA:1.10.10.10 8 57 1.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02410 07ffe581d3e587085c0e676a60f5c563 155 Gene3D G3DSA:3.30.70.920 58 142 1.5E-21 T 14-10-2018 A4R43_17160 4b124e06cf712b95bb8368d25e888d9c 342 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 19 277 2.5E-62 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A4R43_17160 4b124e06cf712b95bb8368d25e888d9c 342 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 146 158 - T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A4R43_17160 4b124e06cf712b95bb8368d25e888d9c 342 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 14 283 14.939 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A4R43_17160 4b124e06cf712b95bb8368d25e888d9c 342 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 13 274 5.4E-40 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A4R43_26720 3721cdb713482512d29b8e2685ba2cbc 325 SUPERFAMILY SSF56219 106 321 6.41E-23 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_26720 3721cdb713482512d29b8e2685ba2cbc 325 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 123 314 2.1E-9 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4R43_26720 3721cdb713482512d29b8e2685ba2cbc 325 Gene3D G3DSA:3.60.10.10 106 324 4.4E-23 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_20010 d769c557df69bbaf92b08bf4e744bb51 614 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_20010 d769c557df69bbaf92b08bf4e744bb51 614 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 4.0E-236 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_20010 d769c557df69bbaf92b08bf4e744bb51 614 SUPERFAMILY SSF143975 4 422 5.89E-134 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_20010 d769c557df69bbaf92b08bf4e744bb51 614 Gene3D G3DSA:3.50.30.80 423 574 1.8E-53 T 14-10-2018 A4R43_20010 d769c557df69bbaf92b08bf4e744bb51 614 Pfam PF00920 Dehydratase family 34 608 3.8E-214 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_20010 d769c557df69bbaf92b08bf4e744bb51 614 SUPERFAMILY SSF52016 423 612 1.8E-58 T 14-10-2018 A4R43_20010 d769c557df69bbaf92b08bf4e744bb51 614 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 44.848 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_20010 d769c557df69bbaf92b08bf4e744bb51 614 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_01760 97414dca8eefb5d336349502ae65e5d7 215 SUPERFAMILY SSF53335 47 206 3.59E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_01760 97414dca8eefb5d336349502ae65e5d7 215 Pfam PF13649 Methyltransferase domain 64 160 2.5E-17 T 14-10-2018 A4R43_01760 97414dca8eefb5d336349502ae65e5d7 215 Gene3D G3DSA:3.40.50.150 41 207 1.7E-33 T 14-10-2018 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 2.6E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.6E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.6E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 222 236 2.6E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 Pfam PF00561 alpha/beta hydrolase fold 25 264 3.9E-27 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 SUPERFAMILY SSF53474 2 278 2.2E-64 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 Gene3D G3DSA:3.40.50.1820 1 279 3.9E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 PRINTS PR00412 Epoxide hydrolase signature 94 107 3.5E-12 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 PRINTS PR00412 Epoxide hydrolase signature 253 275 3.5E-12 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 PRINTS PR00412 Epoxide hydrolase signature 108 121 3.5E-12 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_03165 68cb843eeaab414da4157fec0e3e646f 280 PRINTS PR00412 Epoxide hydrolase signature 30 48 3.5E-12 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 Gene3D G3DSA:3.30.365.10 39 180 2.5E-21 T 14-10-2018 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 Gene3D G3DSA:3.30.365.10 311 534 6.2E-53 T 14-10-2018 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 PIRSF PIRSF036389 2 728 2.9E-227 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related A4R43_02610 c3e319823f92e123f5e17e146118652e 728 Gene3D G3DSA:3.30.365.10 577 727 2.7E-36 T 14-10-2018 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 SMART SM01008 209 283 5.2E-15 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_02610 c3e319823f92e123f5e17e146118652e 728 Gene3D G3DSA:3.30.365.10 335 426 6.2E-53 T 14-10-2018 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 SUPERFAMILY SSF56003 18 241 8.02E-41 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 593 677 4.5E-15 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 309 590 9.6E-32 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 44 191 5.5E-13 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_02610 c3e319823f92e123f5e17e146118652e 728 SUPERFAMILY SSF56003 307 727 1.07E-103 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_31410 a943fd5155752aac624f5b4e066cc494 145 ProSitePatterns PS00552 MerR-type HTH domain signature. 22 44 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31410 a943fd5155752aac624f5b4e066cc494 145 SUPERFAMILY SSF46955 20 111 2.7E-19 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_31410 a943fd5155752aac624f5b4e066cc494 145 SMART SM00422 19 88 2.8E-23 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31410 a943fd5155752aac624f5b4e066cc494 145 Pfam PF13411 MerR HTH family regulatory protein 21 86 4.4E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31410 a943fd5155752aac624f5b4e066cc494 145 Gene3D G3DSA:1.10.1660.10 19 136 2.9E-21 T 14-10-2018 A4R43_27850 617d00eb2321d519a93379b21a92e24f 258 Pfam PF14011 EspG family 14 246 3.9E-47 T 14-10-2018 IPR025734 EspG family A4R43_05165 efbb00174ce6c6c0f018548333310729 604 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 169 331 4.6E-26 T 14-10-2018 IPR000160 GGDEF domain A4R43_05165 efbb00174ce6c6c0f018548333310729 604 Gene3D G3DSA:3.30.70.270 172 345 4.1E-44 T 14-10-2018 A4R43_05165 efbb00174ce6c6c0f018548333310729 604 Pfam PF08448 PAS fold 53 160 4.9E-9 T 14-10-2018 IPR013656 PAS fold-4 A4R43_05165 efbb00174ce6c6c0f018548333310729 604 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 47 169 5.1E-11 T 14-10-2018 IPR000014 PAS domain A4R43_05165 efbb00174ce6c6c0f018548333310729 604 SMART SM00052 343 593 1.2E-10 T 14-10-2018 IPR001633 EAL domain A4R43_05165 efbb00174ce6c6c0f018548333310729 604 SUPERFAMILY SSF55785 44 158 8.03E-11 T 14-10-2018 IPR035965 PAS domain superfamily A4R43_05165 efbb00174ce6c6c0f018548333310729 604 SMART SM00091 46 113 7.3E-6 T 14-10-2018 IPR000014 PAS domain A4R43_05165 efbb00174ce6c6c0f018548333310729 604 Pfam PF00563 EAL domain 353 587 3.9E-30 T 14-10-2018 IPR001633 EAL domain A4R43_05165 efbb00174ce6c6c0f018548333310729 604 Gene3D G3DSA:3.30.450.20 45 171 3.2E-12 T 14-10-2018 A4R43_05165 efbb00174ce6c6c0f018548333310729 604 SMART SM00267 162 333 3.1E-42 T 14-10-2018 IPR000160 GGDEF domain A4R43_05165 efbb00174ce6c6c0f018548333310729 604 SUPERFAMILY SSF55073 178 335 5.18E-35 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_05165 efbb00174ce6c6c0f018548333310729 604 Pfam PF00990 Diguanylate cyclase, GGDEF domain 174 328 1.3E-32 T 14-10-2018 IPR000160 GGDEF domain A4R43_05165 efbb00174ce6c6c0f018548333310729 604 Gene3D G3DSA:3.20.20.450 346 603 5.2E-41 T 14-10-2018 IPR035919 EAL domain superfamily A4R43_05165 efbb00174ce6c6c0f018548333310729 604 SUPERFAMILY SSF141868 351 599 1.31E-28 T 14-10-2018 IPR035919 EAL domain superfamily A4R43_38045 1fd501d6cd539cdaccf0ff463ef957fc 317 SMART SM00849 47 272 1.6E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_38045 1fd501d6cd539cdaccf0ff463ef957fc 317 SUPERFAMILY SSF56281 40 277 2.44E-21 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_38045 1fd501d6cd539cdaccf0ff463ef957fc 317 Gene3D G3DSA:3.60.15.10 26 310 1.1E-31 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_38045 1fd501d6cd539cdaccf0ff463ef957fc 317 Pfam PF13483 Beta-lactamase superfamily domain 43 251 5.5E-12 T 14-10-2018 A4R43_28455 6c899033eaea48595de52868146e097d 239 Gene3D G3DSA:2.40.260.10 83 233 7.2E-24 T 14-10-2018 IPR023365 Sortase domain superfamily A4R43_28455 6c899033eaea48595de52868146e097d 239 Pfam PF04203 Sortase family 87 225 3.1E-15 T 14-10-2018 IPR005754 Sortase family A4R43_28455 6c899033eaea48595de52868146e097d 239 SUPERFAMILY SSF63817 79 214 6.93E-15 T 14-10-2018 IPR023365 Sortase domain superfamily A4R43_05065 7d078675e83e3dfe325155da2cc6d692 153 SUPERFAMILY SSF82649 2 141 1.49E-46 T 14-10-2018 A4R43_05065 7d078675e83e3dfe325155da2cc6d692 153 Pfam PF01592 NifU-like N terminal domain 6 127 2.1E-28 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A4R43_05065 7d078675e83e3dfe325155da2cc6d692 153 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 139 3.0E-49 T 14-10-2018 A4R43_05065 7d078675e83e3dfe325155da2cc6d692 153 Gene3D G3DSA:3.90.1010.10 1 141 2.3E-47 T 14-10-2018 A4R43_09480 8b2a0dc82918b21466bfc3a405efd601 281 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 67 273 2.2E-60 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_09480 8b2a0dc82918b21466bfc3a405efd601 281 Gene3D G3DSA:3.90.850.10 63 280 1.8E-68 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_09480 8b2a0dc82918b21466bfc3a405efd601 281 SUPERFAMILY SSF56529 54 274 1.7E-65 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_38295 2e9bfaae13e5619ba8063bc3b78f520f 257 Gene3D G3DSA:3.60.110.10 1 256 3.3E-74 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_38295 2e9bfaae13e5619ba8063bc3b78f520f 257 SUPERFAMILY SSF56317 1 254 1.44E-62 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_38295 2e9bfaae13e5619ba8063bc3b78f520f 257 Pfam PF00795 Carbon-nitrogen hydrolase 20 239 6.5E-44 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_38295 2e9bfaae13e5619ba8063bc3b78f520f 257 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 135 155 - T 14-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site A4R43_13320 3a07708ca81a1e9043f1330b5dc3b39e 272 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 14 209 5.4E-13 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase A4R43_13320 3a07708ca81a1e9043f1330b5dc3b39e 272 Gene3D G3DSA:2.60.120.620 1 262 1.3E-35 T 14-10-2018 A4R43_13320 3a07708ca81a1e9043f1330b5dc3b39e 272 SUPERFAMILY SSF51197 12 247 6.45E-33 T 14-10-2018 A4R43_28035 b01c34ad9c2f9caf83b27486f452784c 301 Pfam PF04228 Putative neutral zinc metallopeptidase 13 295 3.5E-76 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative A4R43_29100 5369b0c7e4d2a177a7768a778c99558b 479 Gene3D G3DSA:3.60.40.10 2 236 2.1E-69 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_29100 5369b0c7e4d2a177a7768a778c99558b 479 SMART SM00332 2 233 8.9E-32 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_29100 5369b0c7e4d2a177a7768a778c99558b 479 SUPERFAMILY SSF81606 4 234 1.07E-64 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_29100 5369b0c7e4d2a177a7768a778c99558b 479 SMART SM00331 11 235 5.5E-37 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_29100 5369b0c7e4d2a177a7768a778c99558b 479 Pfam PF13672 Protein phosphatase 2C 18 200 8.7E-13 T 14-10-2018 A4R43_02170 1c5ec51bd90fe67859f0a98b90294d70 176 Gene3D G3DSA:3.40.1410.10 13 172 1.3E-38 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_02170 1c5ec51bd90fe67859f0a98b90294d70 176 Pfam PF07702 UTRA domain 33 164 1.3E-23 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_02170 1c5ec51bd90fe67859f0a98b90294d70 176 SUPERFAMILY SSF64288 25 173 1.09E-29 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_02170 1c5ec51bd90fe67859f0a98b90294d70 176 SMART SM00866 28 169 1.2E-19 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_35735 3dfbae11bb45c03e3a78238d58133e45 207 SUPERFAMILY SSF46689 13 93 1.28E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35735 3dfbae11bb45c03e3a78238d58133e45 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 1.2E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35735 3dfbae11bb45c03e3a78238d58133e45 207 Gene3D G3DSA:1.10.357.10 67 204 1.1E-16 T 14-10-2018 A4R43_35735 3dfbae11bb45c03e3a78238d58133e45 207 SUPERFAMILY SSF48498 92 200 7.5E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_35735 3dfbae11bb45c03e3a78238d58133e45 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35735 3dfbae11bb45c03e3a78238d58133e45 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35735 3dfbae11bb45c03e3a78238d58133e45 207 Gene3D G3DSA:1.10.10.60 3 66 2.3E-14 T 14-10-2018 A4R43_29045 3d375b662aa0d1769f0e5bdc91430a7d 497 Gene3D G3DSA:3.10.105.10 269 471 1.3E-94 T 14-10-2018 A4R43_29045 3d375b662aa0d1769f0e5bdc91430a7d 497 SUPERFAMILY SSF53850 29 485 2.17E-109 T 14-10-2018 A4R43_29045 3d375b662aa0d1769f0e5bdc91430a7d 497 Gene3D G3DSA:3.40.190.10 187 482 1.3E-94 T 14-10-2018 A4R43_29045 3d375b662aa0d1769f0e5bdc91430a7d 497 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 403 2.6E-74 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_29045 3d375b662aa0d1769f0e5bdc91430a7d 497 Gene3D G3DSA:3.90.76.10 57 186 1.3E-94 T 14-10-2018 A4R43_29045 3d375b662aa0d1769f0e5bdc91430a7d 497 PIRSF PIRSF002741 1 492 1.3E-76 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_39230 167e0e0ea0e8d8262d8b6f2a889cef92 304 SUPERFAMILY SSF52540 3 225 1.04E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39230 167e0e0ea0e8d8262d8b6f2a889cef92 304 SMART SM00382 26 209 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_39230 167e0e0ea0e8d8262d8b6f2a889cef92 304 Pfam PF00005 ABC transporter 18 160 2.9E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_39230 167e0e0ea0e8d8262d8b6f2a889cef92 304 Gene3D G3DSA:3.40.50.300 1 234 1.3E-67 T 14-10-2018 A4R43_39230 167e0e0ea0e8d8262d8b6f2a889cef92 304 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_00610 ba86ddc0a65f66d53b3e97caa42a89f0 323 SMART SM00345 30 89 9.6E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_00610 ba86ddc0a65f66d53b3e97caa42a89f0 323 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 7.5E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_00610 ba86ddc0a65f66d53b3e97caa42a89f0 323 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 7.5E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_00610 ba86ddc0a65f66d53b3e97caa42a89f0 323 Gene3D G3DSA:1.10.10.10 23 141 8.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00610 ba86ddc0a65f66d53b3e97caa42a89f0 323 SUPERFAMILY SSF46785 19 101 8.09E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00610 ba86ddc0a65f66d53b3e97caa42a89f0 323 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 89 5.7E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_31165 41e5176ff6fb98da1f324be002aefb59 273 SUPERFAMILY SSF53850 8 270 2.78E-59 T 14-10-2018 A4R43_31165 41e5176ff6fb98da1f324be002aefb59 273 SMART SM00062 48 270 1.8E-54 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_31165 41e5176ff6fb98da1f324be002aefb59 273 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 269 3.5E-55 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_31165 41e5176ff6fb98da1f324be002aefb59 273 Gene3D G3DSA:3.40.190.10 53 266 1.4E-60 T 14-10-2018 A4R43_31165 41e5176ff6fb98da1f324be002aefb59 273 Gene3D G3DSA:3.40.190.10 135 229 1.4E-60 T 14-10-2018 A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 SUPERFAMILY SSF51735 6 237 1.04E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 236 1.2E-56 T 14-10-2018 A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 180 0.0097 T 14-10-2018 A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 Gene3D G3DSA:3.40.50.720 1 239 7.9E-76 T 14-10-2018 A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 3.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 3.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 3.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 3.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 3.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 4.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 4.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38160 f0da1527b38cec5872a7b0c4747f746c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 4.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 Gene3D G3DSA:1.25.40.20 7 157 1.8E-23 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 Gene3D G3DSA:1.25.40.20 169 305 5.2E-26 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 SMART SM00248 206 235 0.079 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 SMART SM00248 174 203 250.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 SMART SM00248 104 133 66.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 SMART SM00248 70 99 0.25 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 SMART SM00248 37 66 14.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 SMART SM00248 246 275 7.0E-5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 Pfam PF12796 Ankyrin repeats (3 copies) 179 277 1.5E-13 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 Pfam PF12796 Ankyrin repeats (3 copies) 45 128 9.3E-11 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain A4R43_19980 95c1b045538af058c05bd5c2b9c72a4b 306 SUPERFAMILY SSF48403 9 301 4.48E-39 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4R43_06100 e1d1609af7896b7dec876b32830de497 643 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 63 1.1E-6 T 14-10-2018 A4R43_06100 e1d1609af7896b7dec876b32830de497 643 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 413 435 1.1E-6 T 14-10-2018 A4R43_06100 e1d1609af7896b7dec876b32830de497 643 SUPERFAMILY SSF56425 269 411 4.93E-32 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_06100 e1d1609af7896b7dec876b32830de497 643 Gene3D G3DSA:1.20.58.100 482 598 6.1E-23 T 14-10-2018 A4R43_06100 e1d1609af7896b7dec876b32830de497 643 SUPERFAMILY SSF46977 502 642 1.02E-41 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_06100 e1d1609af7896b7dec876b32830de497 643 Gene3D G3DSA:3.90.700.10 300 424 6.9E-100 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_06100 e1d1609af7896b7dec876b32830de497 643 SUPERFAMILY SSF51905 38 459 2.39E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_06100 e1d1609af7896b7dec876b32830de497 643 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 44 642 1.5E-302 T 14-10-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 A4R43_06100 e1d1609af7896b7dec876b32830de497 643 Pfam PF02910 Fumarate reductase flavoprotein C-term 510 642 5.9E-35 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_06100 e1d1609af7896b7dec876b32830de497 643 Gene3D G3DSA:3.50.50.60 44 458 6.9E-100 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_06100 e1d1609af7896b7dec876b32830de497 643 Pfam PF00890 FAD binding domain 44 449 1.0E-58 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_22965 8b25f36cda6d9e4c39439a829388f268 517 Pfam PF13556 PucR C-terminal helix-turn-helix domain 456 511 5.2E-18 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_22965 8b25f36cda6d9e4c39439a829388f268 517 Gene3D G3DSA:1.10.10.2840 384 517 4.1E-19 T 14-10-2018 A4R43_06460 a16f892fe4a11550e7f4a0c9b88f9379 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 317 2.5E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_06460 a16f892fe4a11550e7f4a0c9b88f9379 325 SUPERFAMILY SSF161098 76 308 2.75E-59 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06460 a16f892fe4a11550e7f4a0c9b88f9379 325 Gene3D G3DSA:1.10.3720.10 72 321 3.0E-66 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 SUPERFAMILY SSF56059 471 667 5.3E-27 T 14-10-2018 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 SMART SM00881 8 103 1.7E-24 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 144 281 4.2E-41 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 SUPERFAMILY SSF52210 288 449 2.22E-24 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 Gene3D G3DSA:3.40.50.261 286 449 4.6E-28 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 Gene3D G3DSA:3.40.50.261 130 283 4.5E-42 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 Pfam PF13380 CoA binding domain 13 128 1.4E-19 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 SUPERFAMILY SSF52210 142 282 1.7E-32 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 Gene3D G3DSA:3.40.50.720 7 129 1.9E-28 T 14-10-2018 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 Gene3D G3DSA:3.30.1490.20 484 552 6.1E-52 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 Gene3D G3DSA:3.30.470.20 471 667 6.1E-52 T 14-10-2018 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 Pfam PF13549 ATP-grasp domain 470 668 2.2E-43 T 14-10-2018 A4R43_27965 701e3d551033ce0459451d1e4860b00e 676 SUPERFAMILY SSF51735 7 129 9.15E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 Gene3D G3DSA:3.50.50.60 246 351 2.6E-34 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 310 5.1E-36 T 14-10-2018 A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 136 151 5.1E-36 T 14-10-2018 A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 326 5.1E-36 T 14-10-2018 A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 290 5.1E-36 T 14-10-2018 A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 259 274 5.1E-36 T 14-10-2018 A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 Pfam PF01494 FAD binding domain 1 324 5.6E-88 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 Gene3D G3DSA:3.50.50.60 1 169 4.5E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 Gene3D G3DSA:3.30.70.2450 170 245 3.3E-23 T 14-10-2018 A4R43_34660 63b212d1ad4031e93938b4ac74364136 436 SUPERFAMILY SSF51905 1 335 3.01E-61 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_06370 96bfd671503c8f98e8759f41add3983f 360 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 232 8.8E-13 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A4R43_06370 96bfd671503c8f98e8759f41add3983f 360 Gene3D G3DSA:3.40.50.720 7 315 2.2E-86 T 14-10-2018 A4R43_06370 96bfd671503c8f98e8759f41add3983f 360 Gene3D G3DSA:3.30.360.10 130 338 2.2E-86 T 14-10-2018 A4R43_06370 96bfd671503c8f98e8759f41add3983f 360 SUPERFAMILY SSF55347 133 271 3.6E-29 T 14-10-2018 A4R43_06370 96bfd671503c8f98e8759f41add3983f 360 SUPERFAMILY SSF51735 3 159 3.49E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_06370 96bfd671503c8f98e8759f41add3983f 360 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 116 5.1E-24 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Gene3D G3DSA:3.40.47.10 1 443 1.7E-159 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 249 5.0E-68 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 375 485 4.6E-20 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 SUPERFAMILY SSF53901 3 422 1.92E-79 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Pfam PF00550 Phosphopantetheine attachment site 877 936 2.1E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 SUPERFAMILY SSF52151 511 781 1.7E-72 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 ProSitePatterns PS00012 Phosphopantetheine attachment site. 899 914 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 257 372 2.4E-41 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 SMART SM00825 Beta-ketoacyl synthase 5 425 1.2E-173 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Gene3D G3DSA:3.40.366.10 511 794 7.8E-136 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Gene3D G3DSA:1.10.1200.10 868 946 4.8E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Pfam PF00698 Acyl transferase domain 513 772 3.1E-48 T 14-10-2018 IPR014043 Acyl transferase A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Gene3D G3DSA:3.30.70.3290 444 823 7.8E-136 T 14-10-2018 A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 SUPERFAMILY SSF55048 633 689 2.09E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 515 793 2.7E-95 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 Gene3D G3DSA:3.30.70.250 634 690 7.8E-136 T 14-10-2018 A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 SUPERFAMILY SSF47336 869 936 3.53E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08315 464ebeec6735fb293f3e9951430c0992 976 SMART SM00823 Phosphopantetheine attachment site 875 943 9.8E-10 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 SUPERFAMILY SSF88659 80 165 4.49E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 Gene3D G3DSA:3.10.450.50 170 297 3.9E-6 T 14-10-2018 A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 Gene3D G3DSA:1.10.1740.10 1 81 5.4E-10 T 14-10-2018 A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 Pfam PF08281 Sigma-70, region 4 110 161 4.1E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 Pfam PF04542 Sigma-70 region 2 15 78 1.2E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 162 8.5E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 SUPERFAMILY SSF54427 176 292 3.32E-15 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 SUPERFAMILY SSF88946 11 93 3.49E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 12 290 1.0E-105 T 14-10-2018 IPR014303 RNA polymerase sigma-70, ECF type A4R43_12875 39f7efcc9b8b4c9aa602d17604440ab7 299 Gene3D G3DSA:1.10.10.10 94 166 1.7E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13255 17f899b6d2f21dd14110243cd23d6797 412 SUPERFAMILY SSF52266 198 405 9.47E-33 T 14-10-2018 A4R43_13255 17f899b6d2f21dd14110243cd23d6797 412 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 202 400 4.1E-15 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_13255 17f899b6d2f21dd14110243cd23d6797 412 Gene3D G3DSA:3.40.50.1110 175 406 8.2E-25 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_11410 5aef5ac7c970f85bdf8fbd44dd76167c 577 SMART SM00382 358 542 8.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_11410 5aef5ac7c970f85bdf8fbd44dd76167c 577 Gene3D G3DSA:3.40.50.300 328 576 4.2E-76 T 14-10-2018 A4R43_11410 5aef5ac7c970f85bdf8fbd44dd76167c 577 SUPERFAMILY SSF90123 3 314 4.97E-58 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_11410 5aef5ac7c970f85bdf8fbd44dd76167c 577 SUPERFAMILY SSF52540 328 564 2.97E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11410 5aef5ac7c970f85bdf8fbd44dd76167c 577 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_11410 5aef5ac7c970f85bdf8fbd44dd76167c 577 Pfam PF00005 ABC transporter 350 496 6.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_11410 5aef5ac7c970f85bdf8fbd44dd76167c 577 Pfam PF00664 ABC transporter transmembrane region 16 282 5.8E-30 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_11410 5aef5ac7c970f85bdf8fbd44dd76167c 577 Gene3D G3DSA:1.20.1560.10 1 314 2.0E-62 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_32565 2cc011d85787fe1d77c8d3cb5fb9771b 142 Gene3D G3DSA:3.10.129.10 1 133 1.6E-38 T 14-10-2018 A4R43_32565 2cc011d85787fe1d77c8d3cb5fb9771b 142 Pfam PF03061 Thioesterase superfamily 18 102 3.0E-19 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_32565 2cc011d85787fe1d77c8d3cb5fb9771b 142 SUPERFAMILY SSF54637 3 132 1.0E-37 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_32565 2cc011d85787fe1d77c8d3cb5fb9771b 142 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 7 115 1.9E-23 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A4R43_32565 2cc011d85787fe1d77c8d3cb5fb9771b 142 PIRSF PIRSF003230 1 135 1.5E-24 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A4R43_24280 7cd87289896aec52b0a186c0b2b2c067 421 Gene3D G3DSA:1.20.1250.20 228 419 1.5E-19 T 14-10-2018 A4R43_24280 7cd87289896aec52b0a186c0b2b2c067 421 SUPERFAMILY SSF103473 30 418 1.7E-46 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_24280 7cd87289896aec52b0a186c0b2b2c067 421 Gene3D G3DSA:1.20.1250.20 17 217 1.4E-20 T 14-10-2018 A4R43_24280 7cd87289896aec52b0a186c0b2b2c067 421 Pfam PF07690 Major Facilitator Superfamily 21 381 1.5E-30 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_26725 b8b4edefb6b71e0417ae5d1c87398674 322 SMART SM00382 29 218 9.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26725 b8b4edefb6b71e0417ae5d1c87398674 322 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_26725 b8b4edefb6b71e0417ae5d1c87398674 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 308 9.5E-106 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_26725 b8b4edefb6b71e0417ae5d1c87398674 322 Gene3D G3DSA:3.40.50.300 1 236 3.9E-64 T 14-10-2018 A4R43_26725 b8b4edefb6b71e0417ae5d1c87398674 322 Pfam PF00005 ABC transporter 20 163 5.2E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_26725 b8b4edefb6b71e0417ae5d1c87398674 322 SUPERFAMILY SSF52540 4 226 3.65E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11705 51a967d44c8100cc9824033941c9d651 587 Gene3D G3DSA:3.30.200.20 1 82 1.3E-19 T 14-10-2018 A4R43_11705 51a967d44c8100cc9824033941c9d651 587 Pfam PF00069 Protein kinase domain 11 248 1.3E-41 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_11705 51a967d44c8100cc9824033941c9d651 587 SUPERFAMILY SSF56112 8 254 3.37E-63 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_11705 51a967d44c8100cc9824033941c9d651 587 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_11705 51a967d44c8100cc9824033941c9d651 587 Gene3D G3DSA:1.10.510.10 83 273 1.7E-40 T 14-10-2018 A4R43_11260 94780b740c792b89e4e38cf0e61f5e20 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4R43_11260 94780b740c792b89e4e38cf0e61f5e20 127 SUPERFAMILY SSF51230 4 125 1.57E-43 T 14-10-2018 IPR011053 Single hybrid motif A4R43_11260 94780b740c792b89e4e38cf0e61f5e20 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 126 39.556 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A4R43_11260 94780b740c792b89e4e38cf0e61f5e20 127 Pfam PF01597 Glycine cleavage H-protein 7 125 1.3E-43 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A4R43_11260 94780b740c792b89e4e38cf0e61f5e20 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 125 6.5E-49 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A4R43_11260 94780b740c792b89e4e38cf0e61f5e20 127 Gene3D G3DSA:2.40.50.100 2 126 5.1E-50 T 14-10-2018 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 Gene3D G3DSA:3.30.1360.70 3 110 2.0E-21 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 31 551 1.8E-121 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 SMART SM01016 4 93 2.1E-31 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 551 25.54 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 Gene3D G3DSA:1.10.730.10 424 551 2.6E-150 T 14-10-2018 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 Pfam PF05746 DALR anticodon binding domain 429 551 2.8E-38 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 SUPERFAMILY SSF55190 5 113 6.67E-21 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 SUPERFAMILY SSF52374 121 440 5.63E-80 T 14-10-2018 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 SUPERFAMILY SSF47323 423 551 1.7E-37 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 25 93 8.5E-21 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 Gene3D G3DSA:3.40.50.620 122 423 2.6E-150 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 Pfam PF00750 tRNA synthetases class I (R) 102 391 2.7E-14 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 SMART SM00836 429 551 2.0E-57 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 1.5E-22 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 1.5E-22 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 1.5E-22 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4R43_22465 21c5baa117bf7589c806c3c912deedfb 551 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 1.5E-22 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 SUPERFAMILY SSF56112 18 280 5.4E-57 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 Gene3D G3DSA:2.130.10.10 467 585 6.5E-14 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 Gene3D G3DSA:2.130.10.10 361 466 1.8E-15 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 Pfam PF00069 Protein kinase domain 21 269 3.4E-37 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 Pfam PF00400 WD domain, G-beta repeat 379 405 0.11 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 SUPERFAMILY SSF82171 378 584 1.26E-27 T 14-10-2018 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 27 49 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 139 151 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 SMART SM00320 367 405 0.051 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 SMART SM00320 460 499 18.0 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 SMART SM00320 502 546 92.0 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 SMART SM00320 408 453 44.0 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 Gene3D G3DSA:1.10.510.10 102 293 1.7E-44 T 14-10-2018 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 Gene3D G3DSA:3.30.200.20 14 99 2.3E-14 T 14-10-2018 A4R43_02150 e533b8ef4d37accb9a366237d41787ec 585 SMART SM00220 21 278 1.1E-36 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_26015 454ccbe04fcb8bb6820917ce6d0000ce 323 SUPERFAMILY SSF53850 40 257 4.27E-20 T 14-10-2018 A4R43_26015 454ccbe04fcb8bb6820917ce6d0000ce 323 Gene3D G3DSA:3.40.190.10 148 319 5.1E-18 T 14-10-2018 A4R43_26015 454ccbe04fcb8bb6820917ce6d0000ce 323 Gene3D G3DSA:3.40.190.10 40 147 1.1E-9 T 14-10-2018 A4R43_26015 454ccbe04fcb8bb6820917ce6d0000ce 323 Pfam PF13379 NMT1-like family 36 260 8.3E-14 T 14-10-2018 A4R43_38290 474b0ed907cd094c822c33410def0b5e 563 Gene3D G3DSA:1.10.405.40 129 263 2.0E-189 T 14-10-2018 A4R43_38290 474b0ed907cd094c822c33410def0b5e 563 Pfam PF01593 Flavin containing amine oxidoreductase 59 534 1.7E-46 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4R43_38290 474b0ed907cd094c822c33410def0b5e 563 Gene3D G3DSA:3.50.50.60 38 547 2.0E-189 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38290 474b0ed907cd094c822c33410def0b5e 563 Gene3D G3DSA:3.90.660.10 88 483 2.0E-189 T 14-10-2018 A4R43_38290 474b0ed907cd094c822c33410def0b5e 563 SUPERFAMILY SSF51905 49 539 2.37E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38290 474b0ed907cd094c822c33410def0b5e 563 SUPERFAMILY SSF54373 362 477 6.02E-28 T 14-10-2018 A4R43_35860 05df0acd98435c120d0c2f326f2e3cb8 294 Gene3D G3DSA:3.40.50.1820 1 288 4.0E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35860 05df0acd98435c120d0c2f326f2e3cb8 294 Pfam PF12146 Serine aminopeptidase, S33 26 274 1.8E-23 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 A4R43_35860 05df0acd98435c120d0c2f326f2e3cb8 294 SUPERFAMILY SSF53474 5 286 1.07E-52 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02070 66681eefa0438861e9ce3a35189026d2 342 Pfam PF02615 Malate/L-lactate dehydrogenase 5 317 1.3E-107 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 A4R43_02070 66681eefa0438861e9ce3a35189026d2 342 SUPERFAMILY SSF89733 3 336 1.7E-99 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 A4R43_02070 66681eefa0438861e9ce3a35189026d2 342 Gene3D G3DSA:3.30.1370.60 68 316 4.4E-111 T 14-10-2018 A4R43_02070 66681eefa0438861e9ce3a35189026d2 342 Gene3D G3DSA:1.10.1530.10 11 331 4.4E-111 T 14-10-2018 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 SUPERFAMILY SSF48498 77 156 5.21E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 Gene3D G3DSA:1.10.357.10 47 188 2.4E-22 T 14-10-2018 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 Gene3D G3DSA:1.10.357.10 248 382 2.2E-21 T 14-10-2018 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 SUPERFAMILY SSF46689 206 275 7.18E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 SUPERFAMILY SSF46689 4 69 3.54E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 Gene3D G3DSA:1.10.10.60 4 46 4.4E-17 T 14-10-2018 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 Gene3D G3DSA:1.10.10.60 205 246 5.9E-18 T 14-10-2018 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 7.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 7.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 4.7E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11820 78f865685ca77d1bc31f12e0ecdc8e74 382 Pfam PF00440 Bacterial regulatory proteins, tetR family 210 256 4.1E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05715 5b5f21b27d1b0f439f66acb4979004d2 438 Gene3D G3DSA:1.20.1250.20 7 199 3.6E-43 T 14-10-2018 A4R43_05715 5b5f21b27d1b0f439f66acb4979004d2 438 Pfam PF07690 Major Facilitator Superfamily 23 302 4.1E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_05715 5b5f21b27d1b0f439f66acb4979004d2 438 SUPERFAMILY SSF103473 9 434 1.09E-79 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_05715 5b5f21b27d1b0f439f66acb4979004d2 438 PIRSF PIRSF002808 1 436 3.7E-35 T 14-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 A4R43_05715 5b5f21b27d1b0f439f66acb4979004d2 438 Gene3D G3DSA:1.20.1250.20 231 427 6.0E-25 T 14-10-2018 A4R43_23335 e7eeff4fa46810a8858ac54dac1064bd 307 SUPERFAMILY SSF161098 96 284 1.44E-23 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23335 e7eeff4fa46810a8858ac54dac1064bd 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 303 7.0E-31 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_23335 e7eeff4fa46810a8858ac54dac1064bd 307 Gene3D G3DSA:1.10.3720.10 90 298 9.9E-23 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23335 e7eeff4fa46810a8858ac54dac1064bd 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 78 2.0E-11 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4R43_33970 ff79f83b021323d29e6d799d0b482bf8 37 SUPERFAMILY SSF57840 2 37 2.49E-15 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33970 ff79f83b021323d29e6d799d0b482bf8 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 6.6E-21 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33970 ff79f83b021323d29e6d799d0b482bf8 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 4.0E-9 T 14-10-2018 A4R43_33970 ff79f83b021323d29e6d799d0b482bf8 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33970 ff79f83b021323d29e6d799d0b482bf8 37 Pfam PF00444 Ribosomal protein L36 2 37 1.8E-16 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33970 ff79f83b021323d29e6d799d0b482bf8 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.29 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_08055 29da9cf010cb789ee0c8a8e82d43e4b7 305 Pfam PF08279 HTH domain 3 51 5.1E-12 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_08055 29da9cf010cb789ee0c8a8e82d43e4b7 305 PIRSF PIRSF016838 1 303 8.7E-27 T 14-10-2018 IPR028349 Protein PafC A4R43_08055 29da9cf010cb789ee0c8a8e82d43e4b7 305 Gene3D G3DSA:1.10.10.10 1 58 3.5E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08055 29da9cf010cb789ee0c8a8e82d43e4b7 305 SUPERFAMILY SSF46785 2 55 1.65E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08055 29da9cf010cb789ee0c8a8e82d43e4b7 305 Pfam PF13280 WYL domain 131 296 1.4E-24 T 14-10-2018 IPR026881 WYL domain A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 Pfam PF07739 TipAS antibiotic-recognition domain 127 241 3.4E-32 T 14-10-2018 IPR012925 TipAS antibiotic-recognition domain A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 SUPERFAMILY SSF46955 3 106 4.4E-24 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 Pfam PF13411 MerR HTH family regulatory protein 4 70 8.8E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.0E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.0E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.0E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 Gene3D G3DSA:1.10.1660.10 1 136 1.8E-35 T 14-10-2018 A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 SMART SM00422 3 72 6.3E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 SUPERFAMILY SSF89082 157 244 2.62E-21 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain A4R43_31065 3cc5a72a9ae120ac8bf046e696958d2e 248 Gene3D G3DSA:1.10.490.50 156 246 1.0E-21 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain A4R43_03920 d7c7a05b8b7ab761b1daa5d0127ba9aa 201 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 127 5.7E-16 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_03920 d7c7a05b8b7ab761b1daa5d0127ba9aa 201 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 12 193 6.4E-36 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_03920 d7c7a05b8b7ab761b1daa5d0127ba9aa 201 SUPERFAMILY SSF109854 5 131 6.41E-20 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_03920 d7c7a05b8b7ab761b1daa5d0127ba9aa 201 Gene3D G3DSA:1.20.120.450 2 146 1.7E-13 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_36040 fa18e0c336c7f4bc627838bea91fd78c 363 Gene3D G3DSA:3.40.50.1240 157 363 2.0E-53 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_36040 fa18e0c336c7f4bc627838bea91fd78c 363 SUPERFAMILY SSF53254 156 362 6.68E-52 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_36040 fa18e0c336c7f4bc627838bea91fd78c 363 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 160 357 1.7E-56 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_36040 fa18e0c336c7f4bc627838bea91fd78c 363 Gene3D G3DSA:3.30.420.10 1 137 6.9E-42 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_36040 fa18e0c336c7f4bc627838bea91fd78c 363 Pfam PF13456 Reverse transcriptase-like 5 127 2.9E-25 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A4R43_36040 fa18e0c336c7f4bc627838bea91fd78c 363 SUPERFAMILY SSF53098 2 126 3.41E-31 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_36040 fa18e0c336c7f4bc627838bea91fd78c 363 SMART SM00855 158 318 2.5E-19 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_36040 fa18e0c336c7f4bc627838bea91fd78c 363 PIRSF PIRSF036922 1 363 1.1E-161 T 14-10-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 SUPERFAMILY SSF55073 297 424 9.26E-12 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 Pfam PF03704 Bacterial transcriptional activator domain 99 244 5.6E-43 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 Pfam PF13191 AAA ATPase domain 443 616 1.2E-13 T 14-10-2018 A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 SUPERFAMILY SSF48452 95 262 1.57E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 SUPERFAMILY SSF46894 2 92 4.54E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 Gene3D G3DSA:3.30.70.1230 279 432 4.1E-9 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 SMART SM01043 99 244 2.5E-44 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 Gene3D G3DSA:1.10.10.10 1 94 2.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 Gene3D G3DSA:1.25.40.10 97 261 3.2E-47 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37620 002bb815ed14c8ef7da3b8970b98abb2 821 SUPERFAMILY SSF52540 442 689 3.2E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04280 051c9f82e655e87e55784aea9bd24a09 211 Gene3D G3DSA:3.30.530.20 8 192 4.3E-41 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_04280 051c9f82e655e87e55784aea9bd24a09 211 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 35 156 1.4E-15 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_04280 051c9f82e655e87e55784aea9bd24a09 211 SUPERFAMILY SSF55961 19 163 1.28E-30 T 14-10-2018 A4R43_13350 6e9b3752cd9b492c4414a01d262e3759 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 1.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13350 6e9b3752cd9b492c4414a01d262e3759 197 Gene3D G3DSA:1.10.357.10 2 191 2.1E-47 T 14-10-2018 A4R43_13350 6e9b3752cd9b492c4414a01d262e3759 197 SUPERFAMILY SSF46689 6 69 7.18E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13350 6e9b3752cd9b492c4414a01d262e3759 197 SUPERFAMILY SSF48498 80 187 2.0E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_13350 6e9b3752cd9b492c4414a01d262e3759 197 Pfam PF16925 Bacterial transcriptional repressor C-terminal 85 183 2.0E-7 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 117 132 - T 14-10-2018 IPR028871 Blue (type 1) copper protein, binding site A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 Pfam PF12245 Bacterial Ig-like domain (group 3) 309 319 2.2 T 14-10-2018 IPR022038 Bacterial Ig-like domain A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 Pfam PF12245 Bacterial Ig-like domain (group 3) 213 224 1.6 T 14-10-2018 IPR022038 Bacterial Ig-like domain A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 SUPERFAMILY SSF81296 175 225 1.59E-5 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 SUPERFAMILY SSF81296 366 413 2.24E-5 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 SUPERFAMILY SSF81296 271 320 6.53E-6 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 Gene3D G3DSA:2.60.40.10 435 518 3.4E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 Gene3D G3DSA:2.60.40.10 242 331 4.5E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 Gene3D G3DSA:2.60.40.10 338 426 1.6E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 Gene3D G3DSA:2.60.40.10 146 235 4.9E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 Gene3D G3DSA:2.60.40.420 19 137 2.1E-8 T 14-10-2018 IPR008972 Cupredoxin A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 SUPERFAMILY SSF49503 34 138 4.38E-9 T 14-10-2018 IPR008972 Cupredoxin A4R43_32340 8e88e1d51b8e430ab77365bb01ac5b0b 614 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 352 414 1.1E-5 T 14-10-2018 A4R43_35550 02799ca282189453f385c4c4efa65963 604 SUPERFAMILY SSF81296 15 114 1.89E-16 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_35550 02799ca282189453f385c4c4efa65963 604 Gene3D G3DSA:2.60.40.10 25 115 1.8E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_35550 02799ca282189453f385c4c4efa65963 604 Pfam PF00759 Glycosyl hydrolase family 9 124 597 5.3E-68 T 14-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4R43_35550 02799ca282189453f385c4c4efa65963 604 Pfam PF02927 Cellulase N-terminal ig-like domain 28 108 7.1E-17 T 14-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 A4R43_35550 02799ca282189453f385c4c4efa65963 604 Gene3D G3DSA:1.50.10.10 127 603 1.6E-54 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_35550 02799ca282189453f385c4c4efa65963 604 SUPERFAMILY SSF48208 119 600 1.11E-56 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_15205 915e9d4807652ba79735c00281fb9ceb 405 Pfam PF00072 Response regulator receiver domain 24 124 8.2E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15205 915e9d4807652ba79735c00281fb9ceb 405 Gene3D G3DSA:3.60.40.10 181 404 1.4E-48 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_15205 915e9d4807652ba79735c00281fb9ceb 405 SUPERFAMILY SSF81606 194 399 2.88E-5 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_15205 915e9d4807652ba79735c00281fb9ceb 405 SMART SM00448 22 133 6.9E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15205 915e9d4807652ba79735c00281fb9ceb 405 SUPERFAMILY SSF52172 21 163 3.98E-22 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_15205 915e9d4807652ba79735c00281fb9ceb 405 Gene3D G3DSA:3.40.50.2300 20 162 1.3E-20 T 14-10-2018 A4R43_15205 915e9d4807652ba79735c00281fb9ceb 405 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 205 399 4.2E-41 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_15205 915e9d4807652ba79735c00281fb9ceb 405 SMART SM00331 178 401 1.8E-18 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_30505 4df16a37306e96945027c40fb5d8bcaa 529 SUPERFAMILY SSF56112 32 217 1.48E-5 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_30505 4df16a37306e96945027c40fb5d8bcaa 529 Gene3D G3DSA:2.60.120.260 386 528 5.2E-5 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_30505 4df16a37306e96945027c40fb5d8bcaa 529 Gene3D G3DSA:3.30.200.20 22 126 2.1E-24 T 14-10-2018 A4R43_30505 4df16a37306e96945027c40fb5d8bcaa 529 Gene3D G3DSA:1.10.510.10 127 278 4.5E-37 T 14-10-2018 A4R43_10760 f720515f0a75552cc7d4b5a65d3cdb8a 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 3.7E-236 T 14-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 A4R43_10760 f720515f0a75552cc7d4b5a65d3cdb8a 452 PIRSF PIRSF018077 1 452 2.3E-182 T 14-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 A4R43_10760 f720515f0a75552cc7d4b5a65d3cdb8a 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 51.189 T 14-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 A4R43_10760 f720515f0a75552cc7d4b5a65d3cdb8a 452 Pfam PF03136 Pup-ligase protein 4 422 4.3E-158 T 14-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 A4R43_09035 71b523cb7396246760bcec6836a2dcf9 234 Gene3D G3DSA:3.40.50.1240 1 202 1.0E-44 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_09035 71b523cb7396246760bcec6836a2dcf9 234 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 1 203 5.9E-96 T 14-10-2018 IPR022492 Phosphomutase MSMEG4193, putative A4R43_09035 71b523cb7396246760bcec6836a2dcf9 234 SMART SM00855 1 158 5.6E-17 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_09035 71b523cb7396246760bcec6836a2dcf9 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 198 1.2E-46 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_09035 71b523cb7396246760bcec6836a2dcf9 234 SUPERFAMILY SSF53254 1 197 7.5E-43 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_27285 f01824a3316fc34113e730e0396b4a2b 143 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 138 1.1E-49 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 A4R43_27285 f01824a3316fc34113e730e0396b4a2b 143 Gene3D G3DSA:3.30.300.20 47 141 8.5E-33 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_27285 f01824a3316fc34113e730e0396b4a2b 143 SUPERFAMILY SSF82784 1 138 1.57E-38 T 14-10-2018 IPR036102 OsmC/Ohr superfamily A4R43_27285 f01824a3316fc34113e730e0396b4a2b 143 Gene3D G3DSA:2.20.25.10 1 46 5.8E-17 T 14-10-2018 A4R43_27285 f01824a3316fc34113e730e0396b4a2b 143 Pfam PF02566 OsmC-like protein 42 137 2.4E-16 T 14-10-2018 IPR003718 OsmC/Ohr family A4R43_10355 e8770c131bcd8fffab3fd273450976d7 382 SUPERFAMILY SSF54826 1 116 1.68E-29 T 14-10-2018 A4R43_10355 e8770c131bcd8fffab3fd273450976d7 382 SMART SM00922 132 237 1.4E-24 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_10355 e8770c131bcd8fffab3fd273450976d7 382 Gene3D G3DSA:3.20.20.120 106 347 2.2E-128 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_10355 e8770c131bcd8fffab3fd273450976d7 382 Pfam PF13378 Enolase C-terminal domain-like 136 357 1.8E-67 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_10355 e8770c131bcd8fffab3fd273450976d7 382 Gene3D G3DSA:3.30.390.10 8 364 2.2E-128 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_10355 e8770c131bcd8fffab3fd273450976d7 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 111 1.5E-15 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_10355 e8770c131bcd8fffab3fd273450976d7 382 SUPERFAMILY SSF51604 99 363 4.08E-85 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_41765 a43813f90b20047aa28e197d53134038 369 Gene3D G3DSA:3.40.50.1820 101 366 7.5E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41765 a43813f90b20047aa28e197d53134038 369 Pfam PF00364 Biotin-requiring enzyme 6 78 1.0E-14 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_41765 a43813f90b20047aa28e197d53134038 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 214 1.2E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_41765 a43813f90b20047aa28e197d53134038 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 317 331 1.2E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_41765 a43813f90b20047aa28e197d53134038 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 228 1.2E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_41765 a43813f90b20047aa28e197d53134038 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 157 172 1.2E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_41765 a43813f90b20047aa28e197d53134038 369 SUPERFAMILY SSF51230 4 92 2.62E-20 T 14-10-2018 IPR011053 Single hybrid motif A4R43_41765 a43813f90b20047aa28e197d53134038 369 Pfam PF12697 Alpha/beta hydrolase family 134 361 9.0E-25 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_41765 a43813f90b20047aa28e197d53134038 369 SUPERFAMILY SSF53474 108 363 7.38E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41765 a43813f90b20047aa28e197d53134038 369 Gene3D G3DSA:2.40.50.100 1 100 4.3E-23 T 14-10-2018 A4R43_37990 0924fcc0a66fe420010d56027fbe170b 196 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 25 191 4.5E-32 T 14-10-2018 IPR000160 GGDEF domain A4R43_37990 0924fcc0a66fe420010d56027fbe170b 196 Pfam PF00990 Diguanylate cyclase, GGDEF domain 25 189 9.7E-34 T 14-10-2018 IPR000160 GGDEF domain A4R43_37990 0924fcc0a66fe420010d56027fbe170b 196 Gene3D G3DSA:3.30.70.270 24 194 2.2E-38 T 14-10-2018 A4R43_37990 0924fcc0a66fe420010d56027fbe170b 196 SMART SM00267 24 193 1.6E-28 T 14-10-2018 IPR000160 GGDEF domain A4R43_37990 0924fcc0a66fe420010d56027fbe170b 196 SUPERFAMILY SSF55073 29 191 7.85E-33 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_21090 e48712ecfea0fc9014fcb4e6e9c70d40 203 Gene3D G3DSA:1.10.357.10 4 201 3.5E-48 T 14-10-2018 A4R43_21090 e48712ecfea0fc9014fcb4e6e9c70d40 203 SUPERFAMILY SSF48498 88 197 4.97E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_21090 e48712ecfea0fc9014fcb4e6e9c70d40 203 SUPERFAMILY SSF46689 7 92 1.1E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21090 e48712ecfea0fc9014fcb4e6e9c70d40 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21090 e48712ecfea0fc9014fcb4e6e9c70d40 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21090 e48712ecfea0fc9014fcb4e6e9c70d40 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 2.3E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21090 e48712ecfea0fc9014fcb4e6e9c70d40 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_39480 0e8fb4dbcff16202ecade2c4195aa4c3 124 Pfam PF01337 Barstar (barnase inhibitor) 32 105 2.7E-23 T 14-10-2018 IPR000468 Barstar (barnase inhibitor) A4R43_39480 0e8fb4dbcff16202ecade2c4195aa4c3 124 Gene3D G3DSA:3.30.370.10 24 106 6.0E-13 T 14-10-2018 IPR035905 Barstar-like superfamily A4R43_39480 0e8fb4dbcff16202ecade2c4195aa4c3 124 SUPERFAMILY SSF52038 26 107 1.31E-20 T 14-10-2018 IPR035905 Barstar-like superfamily A4R43_22410 e6f60852f10a76966b2ca62e16eb5250 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22410 e6f60852f10a76966b2ca62e16eb5250 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22410 e6f60852f10a76966b2ca62e16eb5250 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22410 e6f60852f10a76966b2ca62e16eb5250 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22410 e6f60852f10a76966b2ca62e16eb5250 257 Gene3D G3DSA:3.40.50.1820 7 256 3.5E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22410 e6f60852f10a76966b2ca62e16eb5250 257 SUPERFAMILY SSF53474 6 255 4.05E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22410 e6f60852f10a76966b2ca62e16eb5250 257 Pfam PF00561 alpha/beta hydrolase fold 16 130 2.9E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_17920 de3481dbfcdc6dcce53ba4a3c2607985 377 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 13 363 5.3E-96 T 14-10-2018 IPR010640 Low temperature requirement A A4R43_03640 6270ed65558c33f7dbf5fca59689c39f 330 Gene3D G3DSA:3.40.50.720 23 317 1.2E-76 T 14-10-2018 A4R43_03640 6270ed65558c33f7dbf5fca59689c39f 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_03640 6270ed65558c33f7dbf5fca59689c39f 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 324 2.6E-9 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_03640 6270ed65558c33f7dbf5fca59689c39f 330 Gene3D G3DSA:3.40.50.720 94 291 1.2E-76 T 14-10-2018 A4R43_03640 6270ed65558c33f7dbf5fca59689c39f 330 SUPERFAMILY SSF52283 1 127 1.81E-15 T 14-10-2018 A4R43_03640 6270ed65558c33f7dbf5fca59689c39f 330 SUPERFAMILY SSF51735 97 292 5.87E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03640 6270ed65558c33f7dbf5fca59689c39f 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 292 6.7E-48 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_01855 158ca7d1d09bbc2b918daa1bcff4e6d9 168 SUPERFAMILY SSF69118 16 148 1.02E-26 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_01855 158ca7d1d09bbc2b918daa1bcff4e6d9 168 Pfam PF02627 Carboxymuconolactone decarboxylase family 34 105 8.1E-12 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_01855 158ca7d1d09bbc2b918daa1bcff4e6d9 168 Gene3D G3DSA:1.20.1290.10 19 154 4.2E-28 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_07450 c66713dd91e104f506c59608d0ff6cd2 381 Gene3D G3DSA:3.30.9.10 82 310 4.0E-54 T 14-10-2018 A4R43_07450 c66713dd91e104f506c59608d0ff6cd2 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 359 1.4E-5 T 14-10-2018 A4R43_07450 c66713dd91e104f506c59608d0ff6cd2 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.4E-5 T 14-10-2018 A4R43_07450 c66713dd91e104f506c59608d0ff6cd2 381 SUPERFAMILY SSF51905 1 365 1.55E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07450 c66713dd91e104f506c59608d0ff6cd2 381 Gene3D G3DSA:3.50.50.60 3 346 4.0E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07450 c66713dd91e104f506c59608d0ff6cd2 381 Pfam PF01266 FAD dependent oxidoreductase 2 345 6.6E-40 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_41220 91d8ec90118b50b08722ada40ec60ee6 250 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 8 230 2.6E-60 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A4R43_41220 91d8ec90118b50b08722ada40ec60ee6 250 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 238 26.148 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A4R43_41220 91d8ec90118b50b08722ada40ec60ee6 250 SUPERFAMILY SSF69796 32 235 8.24E-61 T 14-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A4R43_41220 91d8ec90118b50b08722ada40ec60ee6 250 Gene3D G3DSA:3.30.1360.170 24 232 7.0E-61 T 14-10-2018 A4R43_41220 91d8ec90118b50b08722ada40ec60ee6 250 Pfam PF02511 Thymidylate synthase complementing protein 31 222 2.5E-54 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A4R43_20255 9b87a767cc5f0346a9c4dc0c1ce9bb93 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 5 73 1.6E-11 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4R43_20255 9b87a767cc5f0346a9c4dc0c1ce9bb93 102 Gene3D G3DSA:3.30.70.100 1 99 3.1E-34 T 14-10-2018 A4R43_20255 9b87a767cc5f0346a9c4dc0c1ce9bb93 102 SUPERFAMILY SSF54909 4 100 6.44E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_16075 449a792ebf4715df88881d40e5ad0898 287 SUPERFAMILY SSF54637 161 279 8.53E-32 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_16075 449a792ebf4715df88881d40e5ad0898 287 SUPERFAMILY SSF54637 8 160 1.31E-43 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_16075 449a792ebf4715df88881d40e5ad0898 287 Gene3D G3DSA:3.10.129.10 161 286 2.6E-40 T 14-10-2018 A4R43_16075 449a792ebf4715df88881d40e5ad0898 287 Pfam PF13452 N-terminal half of MaoC dehydratase 8 138 2.8E-21 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 A4R43_16075 449a792ebf4715df88881d40e5ad0898 287 Pfam PF01575 MaoC like domain 163 261 1.7E-29 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_16075 449a792ebf4715df88881d40e5ad0898 287 Gene3D G3DSA:3.10.129.10 3 160 9.8E-48 T 14-10-2018 A4R43_11325 3649d8760a023dca3ab2c3b31ce4f96a 78 Pfam PF00830 Ribosomal L28 family 4 61 1.8E-26 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11325 3649d8760a023dca3ab2c3b31ce4f96a 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 58 8.7E-25 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11325 3649d8760a023dca3ab2c3b31ce4f96a 78 SUPERFAMILY SSF143800 2 77 1.65E-29 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11325 3649d8760a023dca3ab2c3b31ce4f96a 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 20.717 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11325 3649d8760a023dca3ab2c3b31ce4f96a 78 Gene3D G3DSA:2.30.170.40 2 78 8.5E-32 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_26195 99bf4df308baf77e065b24ba7bf3bd58 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 302 5.2E-78 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_26195 99bf4df308baf77e065b24ba7bf3bd58 316 Gene3D G3DSA:3.40.50.1100 9 307 3.8E-102 T 14-10-2018 A4R43_26195 99bf4df308baf77e065b24ba7bf3bd58 316 SUPERFAMILY SSF53686 6 310 5.89E-85 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_26195 99bf4df308baf77e065b24ba7bf3bd58 316 Gene3D G3DSA:3.40.50.1100 49 143 3.8E-102 T 14-10-2018 A4R43_36075 723dcfcd493758ae5cc760b954177da0 137 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 1 130 2.7E-25 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A4R43_36075 723dcfcd493758ae5cc760b954177da0 137 Gene3D G3DSA:3.40.50.2300 1 137 2.6E-38 T 14-10-2018 A4R43_36075 723dcfcd493758ae5cc760b954177da0 137 SMART SM00226 1 132 4.8E-27 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A4R43_36075 723dcfcd493758ae5cc760b954177da0 137 SUPERFAMILY SSF52788 1 133 1.44E-29 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily A4R43_36075 723dcfcd493758ae5cc760b954177da0 137 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 104 119 1.3E-7 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A4R43_36075 723dcfcd493758ae5cc760b954177da0 137 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 31 47 1.3E-7 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A4R43_36075 723dcfcd493758ae5cc760b954177da0 137 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 63 78 1.3E-7 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A4R43_32095 a1098643d9106df3d9ce90e37e8e20f4 379 Pfam PF12849 PBP superfamily domain 46 350 1.8E-55 T 14-10-2018 IPR024370 PBP domain A4R43_32095 a1098643d9106df3d9ce90e37e8e20f4 379 Gene3D G3DSA:3.40.190.10 141 320 2.0E-103 T 14-10-2018 A4R43_32095 a1098643d9106df3d9ce90e37e8e20f4 379 SUPERFAMILY SSF53850 57 378 7.39E-80 T 14-10-2018 A4R43_32095 a1098643d9106df3d9ce90e37e8e20f4 379 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 58 378 2.9E-82 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A4R43_32095 a1098643d9106df3d9ce90e37e8e20f4 379 PIRSF PIRSF002756 7 379 3.9E-110 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A4R43_32095 a1098643d9106df3d9ce90e37e8e20f4 379 Gene3D G3DSA:3.40.190.10 61 365 2.0E-103 T 14-10-2018 A4R43_20360 75de3300da18d430b1b3114d6ca26820 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 3.5E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_20360 75de3300da18d430b1b3114d6ca26820 131 Gene3D G3DSA:3.10.180.10 1 130 1.2E-42 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_20360 75de3300da18d430b1b3114d6ca26820 131 SUPERFAMILY SSF54593 5 126 1.15E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 SMART SM00382 39 405 0.001 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 Gene3D G3DSA:3.40.50.300 10 226 1.3E-55 T 14-10-2018 A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 Gene3D G3DSA:3.40.50.300 285 434 1.3E-25 T 14-10-2018 A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 SMART SM00490 307 418 1.4E-14 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 SMART SM00487 22 239 3.6E-35 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 Pfam PF00270 DEAD/DEAH box helicase 27 210 1.9E-23 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 Pfam PF00271 Helicase conserved C-terminal domain 295 418 1.4E-13 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 SUPERFAMILY SSF52540 36 422 5.08E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16980 db4403b296d8fb6556ac39f98f2d4b01 1542 Pfam PF08494 DEAD/H associated 681 874 4.5E-76 T 14-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 Pfam PF13191 AAA ATPase domain 12 201 1.4E-27 T 14-10-2018 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 ProSitePatterns PS00622 LuxR-type HTH domain signature. 953 980 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 SUPERFAMILY SSF52540 13 271 7.98E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 SMART SM00421 936 993 6.5E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 Pfam PF00196 Bacterial regulatory proteins, luxR family 938 993 1.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 969 981 3.4E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 939 953 3.4E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 953 969 3.4E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 Gene3D G3DSA:1.25.40.10 457 733 2.0E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 SUPERFAMILY SSF48452 475 665 7.59E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 SUPERFAMILY SSF46894 925 999 1.19E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_16270 44c6a462bc87b803d625bc60cb42ccf9 1001 Gene3D G3DSA:1.10.10.10 781 1000 2.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Gene3D G3DSA:3.30.1360.40 244 341 1.4E-202 T 14-10-2018 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Gene3D G3DSA:3.90.199.10 36 495 1.4E-202 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Gene3D G3DSA:1.10.268.10 378 466 1.4E-202 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 815 0.0 T 14-10-2018 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 SUPERFAMILY SSF101904 507 820 4.97E-101 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 SUPERFAMILY SSF56719 34 496 1.16E-173 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Gene3D G3DSA:2.120.10.90 509 817 1.2E-125 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 666 714 3.1E-11 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 562 611 2.0E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 719 766 1.2E-11 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 769 810 4.4E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 619 663 1.7E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 512 559 3.6E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 SMART SM00434 15 473 2.2E-274 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 8 817 23.808 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4R43_30400 977bf6dfa414be6bd11d2de5624f08b3 836 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 480 5.5E-151 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_38395 122efdef8eee03047540abd6dcc07e55 352 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 24 32 - T 14-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A4R43_38395 122efdef8eee03047540abd6dcc07e55 352 SUPERFAMILY SSF50249 197 335 6.28E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_38395 122efdef8eee03047540abd6dcc07e55 352 SUPERFAMILY SSF56091 2 194 4.56E-45 T 14-10-2018 A4R43_38395 122efdef8eee03047540abd6dcc07e55 352 Pfam PF04679 ATP dependent DNA ligase C terminal region 212 326 1.2E-12 T 14-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A4R43_38395 122efdef8eee03047540abd6dcc07e55 352 Gene3D G3DSA:2.40.50.140 196 333 3.6E-27 T 14-10-2018 A4R43_38395 122efdef8eee03047540abd6dcc07e55 352 Gene3D G3DSA:3.30.470.30 3 194 1.1E-43 T 14-10-2018 A4R43_38395 122efdef8eee03047540abd6dcc07e55 352 Pfam PF01068 ATP dependent DNA ligase domain 6 194 4.1E-39 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A4R43_18980 f063e8275bb4350bc5a14d594cc23209 273 SUPERFAMILY SSF52540 21 237 1.46E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_18980 f063e8275bb4350bc5a14d594cc23209 273 Pfam PF00005 ABC transporter 40 179 5.0E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_18980 f063e8275bb4350bc5a14d594cc23209 273 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_18980 f063e8275bb4350bc5a14d594cc23209 273 Gene3D G3DSA:3.40.50.300 19 258 1.0E-66 T 14-10-2018 A4R43_18980 f063e8275bb4350bc5a14d594cc23209 273 SMART SM00382 49 230 1.3E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_06690 6fe6fc7ae066140b04e5b5553f22cb44 428 SUPERFAMILY SSF48264 10 414 1.2E-54 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06690 6fe6fc7ae066140b04e5b5553f22cb44 428 Gene3D G3DSA:1.10.630.10 16 419 6.6E-81 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06690 6fe6fc7ae066140b04e5b5553f22cb44 428 PRINTS PR00359 B-class P450 signature 154 170 5.8E-21 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06690 6fe6fc7ae066140b04e5b5553f22cb44 428 PRINTS PR00359 B-class P450 signature 301 328 5.8E-21 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06690 6fe6fc7ae066140b04e5b5553f22cb44 428 PRINTS PR00359 B-class P450 signature 350 359 5.8E-21 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06690 6fe6fc7ae066140b04e5b5553f22cb44 428 PRINTS PR00359 B-class P450 signature 283 294 5.8E-21 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06690 6fe6fc7ae066140b04e5b5553f22cb44 428 PRINTS PR00359 B-class P450 signature 205 227 5.8E-21 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 Gene3D G3DSA:2.160.10.10 262 449 1.3E-51 T 14-10-2018 A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 4 461 39.625 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 277 309 0.0021 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 326 358 7.9E-5 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 463 3.2E-166 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 SUPERFAMILY SSF53448 6 316 2.7E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 SUPERFAMILY SSF51161 266 466 3.21E-38 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 Gene3D G3DSA:3.90.550.10 2 261 8.3E-72 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_24015 33ab0ba1d96c4d8ab43869f5aeb789a7 489 Pfam PF12804 MobA-like NTP transferase domain 8 144 6.0E-21 T 14-10-2018 IPR025877 MobA-like NTP transferase A4R43_00570 080682bb472ab5e4a3b84c8642e4f0b4 226 Pfam PF00072 Response regulator receiver domain 6 115 8.0E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_00570 080682bb472ab5e4a3b84c8642e4f0b4 226 SUPERFAMILY SSF52172 3 128 2.7E-34 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_00570 080682bb472ab5e4a3b84c8642e4f0b4 226 SUPERFAMILY SSF46894 120 220 8.79E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_00570 080682bb472ab5e4a3b84c8642e4f0b4 226 SMART SM00448 4 114 4.6E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_00570 080682bb472ab5e4a3b84c8642e4f0b4 226 SMART SM00862 146 219 1.8E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_00570 080682bb472ab5e4a3b84c8642e4f0b4 226 Gene3D G3DSA:3.40.50.2300 1 124 4.0E-30 T 14-10-2018 A4R43_00570 080682bb472ab5e4a3b84c8642e4f0b4 226 Gene3D G3DSA:1.10.10.10 125 225 1.3E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00570 080682bb472ab5e4a3b84c8642e4f0b4 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 3.4E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_41430 e6035eaf54e2edb8cd626db1da96d9e0 216 Gene3D G3DSA:2.40.260.10 69 216 3.4E-16 T 14-10-2018 IPR023365 Sortase domain superfamily A4R43_41430 e6035eaf54e2edb8cd626db1da96d9e0 216 SUPERFAMILY SSF63817 68 197 1.41E-9 T 14-10-2018 IPR023365 Sortase domain superfamily A4R43_41430 e6035eaf54e2edb8cd626db1da96d9e0 216 Pfam PF04203 Sortase family 74 215 1.1E-10 T 14-10-2018 IPR005754 Sortase family A4R43_25510 f031ef8965bcd7c1177935376a8281a1 89 SUPERFAMILY SSF47413 12 73 2.82E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_25510 f031ef8965bcd7c1177935376a8281a1 89 SMART SM00530 15 70 6.7E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_25510 f031ef8965bcd7c1177935376a8281a1 89 Gene3D G3DSA:1.10.260.40 12 75 2.5E-22 T 14-10-2018 A4R43_25510 f031ef8965bcd7c1177935376a8281a1 89 Pfam PF01381 Helix-turn-helix 19 68 1.3E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_21990 186e10e3522ef3e78e9b3aaf74d6ead5 229 Pfam PF00005 ABC transporter 19 166 2.1E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_21990 186e10e3522ef3e78e9b3aaf74d6ead5 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 4.6E-86 T 14-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 A4R43_21990 186e10e3522ef3e78e9b3aaf74d6ead5 229 Gene3D G3DSA:3.40.50.300 1 224 2.2E-66 T 14-10-2018 A4R43_21990 186e10e3522ef3e78e9b3aaf74d6ead5 229 SUPERFAMILY SSF52540 1 220 1.22E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21990 186e10e3522ef3e78e9b3aaf74d6ead5 229 SMART SM00382 28 215 1.6E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_21990 186e10e3522ef3e78e9b3aaf74d6ead5 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_13090 e470ece4bbcd26d23d9c34619cc988e8 391 SUPERFAMILY SSF63433 2 98 1.83E-23 T 14-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4R43_13090 e470ece4bbcd26d23d9c34619cc988e8 391 Gene3D G3DSA:2.30.30.230 1 95 4.1E-19 T 14-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4R43_13090 e470ece4bbcd26d23d9c34619cc988e8 391 SUPERFAMILY SSF56529 100 388 3.53E-91 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_13090 e470ece4bbcd26d23d9c34619cc988e8 391 Pfam PF09298 Fumarylacetoacetase N-terminal 16 98 4.3E-18 T 14-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4R43_13090 e470ece4bbcd26d23d9c34619cc988e8 391 Gene3D G3DSA:3.90.850.10 96 390 2.3E-110 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_13090 e470ece4bbcd26d23d9c34619cc988e8 391 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 4 388 5.0E-134 T 14-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4R43_13090 e470ece4bbcd26d23d9c34619cc988e8 391 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 104 385 1.4E-56 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_03245 76cfe1f628e0ce5960c7e83960100166 520 Gene3D G3DSA:3.30.420.40 88 307 1.6E-13 T 14-10-2018 A4R43_03245 76cfe1f628e0ce5960c7e83960100166 520 Gene3D G3DSA:3.90.870.20 338 515 1.4E-52 T 14-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily A4R43_03245 76cfe1f628e0ce5960c7e83960100166 520 Gene3D G3DSA:3.30.420.350 102 300 1.6E-13 T 14-10-2018 A4R43_03245 76cfe1f628e0ce5960c7e83960100166 520 Pfam PF16861 Carbamoyltransferase C-terminus 353 516 2.4E-53 T 14-10-2018 IPR031730 Carbamoyltransferase, C-terminal A4R43_03245 76cfe1f628e0ce5960c7e83960100166 520 Pfam PF02543 Carbamoyltransferase N-terminus 99 307 9.4E-19 T 14-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 Gene3D G3DSA:3.40.50.720 6 251 4.6E-77 T 14-10-2018 A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 250 1.1E-62 T 14-10-2018 A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 17 194 5.8E-4 T 14-10-2018 A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.7E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.7E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 2.7E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.7E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.7E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.7E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 SUPERFAMILY SSF51735 16 251 2.27E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15990 43ec2618fe8b47b5dcbd8925ceea9d7f 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12035 60869d58f6fc64a6f7cff9be41335eae 138 Pfam PF09391 Protein of unknown function (DUF2000) 7 137 5.4E-45 T 14-10-2018 IPR018988 Protein of unknown function DUF2000 A4R43_12035 60869d58f6fc64a6f7cff9be41335eae 138 SUPERFAMILY SSF102462 4 138 2.2E-46 T 14-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A4R43_12035 60869d58f6fc64a6f7cff9be41335eae 138 Gene3D G3DSA:3.40.1490.10 4 138 2.1E-57 T 14-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 21 729 1.8E-263 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Pfam PF01138 3' exoribonuclease family, domain 1 24 155 1.1E-18 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Pfam PF01138 3' exoribonuclease family, domain 1 358 490 3.5E-15 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SUPERFAMILY SSF54211 13 155 2.89E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SMART SM00316 659 730 2.7E-16 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 274 353 1.2E-19 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SUPERFAMILY SSF54211 330 525 4.1E-42 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SUPERFAMILY SSF55666 156 266 3.6E-27 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SUPERFAMILY SSF46915 271 355 8.37E-16 T 14-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SUPERFAMILY SSF54791 592 678 1.75E-17 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Gene3D G3DSA:3.30.230.70 266 587 8.8E-103 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Gene3D G3DSA:2.40.50.140 588 712 9.1E-47 T 14-10-2018 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SUPERFAMILY SSF55666 484 583 2.13E-23 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Pfam PF00575 S1 RNA binding domain 658 727 8.2E-13 T 14-10-2018 IPR003029 S1 domain GO:0003676 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 13 733 27.044 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Pfam PF00013 KH domain 593 650 4.0E-10 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Gene3D G3DSA:3.30.230.70 8 256 3.4E-86 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SMART SM00322 589 654 1.2E-10 T 14-10-2018 IPR004087 K Homology domain GO:0003676 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 9 728 0.0 T 14-10-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 SUPERFAMILY SSF50249 657 727 2.46E-14 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 Pfam PF03725 3' exoribonuclease family, domain 2 493 567 6.6E-5 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_41155 b223dc022e5699736dfb0fc1b89e0b01 755 PIRSF PIRSF005499 11 755 7.1E-284 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4R43_26855 13140b49a280a78f2f44814f73c0b1d0 355 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 22 353 4.1E-116 T 14-10-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated A4R43_26855 13140b49a280a78f2f44814f73c0b1d0 355 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 22 353 2.3E-98 T 14-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 A4R43_26855 13140b49a280a78f2f44814f73c0b1d0 355 Gene3D G3DSA:1.20.150.30 21 141 1.1E-20 T 14-10-2018 A4R43_26855 13140b49a280a78f2f44814f73c0b1d0 355 Pfam PF10103 Zincin-like metallopeptidase 22 350 7.1E-108 T 14-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 A4R43_26855 13140b49a280a78f2f44814f73c0b1d0 355 SUPERFAMILY SSF55486 22 353 9.52E-96 T 14-10-2018 A4R43_20235 7bc3b8ce8455b2c1010d6558594bf4c4 421 SUPERFAMILY SSF53187 51 272 3.59E-32 T 14-10-2018 A4R43_20235 7bc3b8ce8455b2c1010d6558594bf4c4 421 SMART SM00631 53 325 5.5E-4 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_20235 7bc3b8ce8455b2c1010d6558594bf4c4 421 Gene3D G3DSA:3.40.630.10 47 359 1.3E-30 T 14-10-2018 A4R43_20235 7bc3b8ce8455b2c1010d6558594bf4c4 421 Pfam PF00246 Zinc carboxypeptidase 71 267 1.6E-20 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_17760 bd1f1675fb7ce3f88e6cab3b65e691a7 124 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 124 6.1E-34 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A4R43_17760 bd1f1675fb7ce3f88e6cab3b65e691a7 124 Gene3D G3DSA:2.60.300.12 19 124 4.8E-28 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A4R43_17760 bd1f1675fb7ce3f88e6cab3b65e691a7 124 SUPERFAMILY SSF89360 18 111 2.94E-26 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A4R43_17760 bd1f1675fb7ce3f88e6cab3b65e691a7 124 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 106 123 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A4R43_17760 bd1f1675fb7ce3f88e6cab3b65e691a7 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 20 121 2.1E-17 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A4R43_26600 62b05fb085c9248e060b00aa4844a8ca 322 Pfam PF00588 SpoU rRNA Methylase family 169 309 4.4E-34 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4R43_26600 62b05fb085c9248e060b00aa4844a8ca 322 Gene3D G3DSA:3.30.1330.30 65 148 3.4E-9 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_26600 62b05fb085c9248e060b00aa4844a8ca 322 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 76 151 9.5E-17 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A4R43_26600 62b05fb085c9248e060b00aa4844a8ca 322 SMART SM00967 76 152 7.4E-18 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A4R43_26600 62b05fb085c9248e060b00aa4844a8ca 322 SUPERFAMILY SSF55315 69 149 4.24E-15 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_26600 62b05fb085c9248e060b00aa4844a8ca 322 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 75 314 3.8E-59 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 A4R43_26600 62b05fb085c9248e060b00aa4844a8ca 322 Gene3D G3DSA:3.40.1280.10 150 317 8.5E-49 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_26600 62b05fb085c9248e060b00aa4844a8ca 322 SUPERFAMILY SSF75217 141 317 2.22E-43 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_06650 33d6ae825a1748b53b9578ce6c941cf0 207 SUPERFAMILY SSF46689 5 76 5.64E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_06650 33d6ae825a1748b53b9578ce6c941cf0 207 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 151 204 4.6E-14 T 14-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type A4R43_06650 33d6ae825a1748b53b9578ce6c941cf0 207 Gene3D G3DSA:1.10.10.60 4 58 1.1E-18 T 14-10-2018 A4R43_06650 33d6ae825a1748b53b9578ce6c941cf0 207 SUPERFAMILY SSF48498 85 202 1.98E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_06650 33d6ae825a1748b53b9578ce6c941cf0 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 9.3E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06650 33d6ae825a1748b53b9578ce6c941cf0 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06650 33d6ae825a1748b53b9578ce6c941cf0 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06650 33d6ae825a1748b53b9578ce6c941cf0 207 Gene3D G3DSA:1.10.357.10 59 207 6.6E-29 T 14-10-2018 A4R43_26200 d1b248f790766eaa86744de669b63bde 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 1.8E-5 T 14-10-2018 A4R43_26200 d1b248f790766eaa86744de669b63bde 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 1.8E-5 T 14-10-2018 A4R43_26200 d1b248f790766eaa86744de669b63bde 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 1.8E-5 T 14-10-2018 A4R43_26200 d1b248f790766eaa86744de669b63bde 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 1.8E-5 T 14-10-2018 A4R43_26200 d1b248f790766eaa86744de669b63bde 502 Gene3D G3DSA:1.20.1720.10 17 253 7.8E-53 T 14-10-2018 A4R43_26200 d1b248f790766eaa86744de669b63bde 502 SUPERFAMILY SSF103473 8 462 1.14E-68 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_26200 d1b248f790766eaa86744de669b63bde 502 Gene3D G3DSA:1.20.1250.20 263 463 1.4E-20 T 14-10-2018 A4R43_26200 d1b248f790766eaa86744de669b63bde 502 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 418 2.8E-73 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4R43_26200 d1b248f790766eaa86744de669b63bde 502 Pfam PF07690 Major Facilitator Superfamily 22 414 1.1E-51 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_22950 4612c7fc374c3d83b6b8e9d341cd7c40 360 Gene3D G3DSA:3.40.50.1820 26 353 1.1E-129 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22950 4612c7fc374c3d83b6b8e9d341cd7c40 360 Gene3D G3DSA:1.10.1740.110 185 283 1.1E-129 T 14-10-2018 A4R43_22950 4612c7fc374c3d83b6b8e9d341cd7c40 360 SUPERFAMILY SSF53474 19 359 8.67E-93 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22950 4612c7fc374c3d83b6b8e9d341cd7c40 360 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 23 357 6.3E-131 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 A4R43_22950 4612c7fc374c3d83b6b8e9d341cd7c40 360 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 2 360 30.464 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 A4R43_22950 4612c7fc374c3d83b6b8e9d341cd7c40 360 Pfam PF00561 alpha/beta hydrolase fold 50 346 2.1E-30 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22950 4612c7fc374c3d83b6b8e9d341cd7c40 360 PIRSF PIRSF000443 12 360 1.0E-123 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 A4R43_33460 6d3108933ecfea5d69a0104ad6704b61 378 Pfam PF07730 Histidine kinase 193 258 7.2E-14 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_33460 6d3108933ecfea5d69a0104ad6704b61 378 SUPERFAMILY SSF55874 278 376 6.68E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_33460 6d3108933ecfea5d69a0104ad6704b61 378 Gene3D G3DSA:3.30.565.10 264 377 1.2E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_33460 6d3108933ecfea5d69a0104ad6704b61 378 SMART SM00387 291 378 5.8E-4 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_19310 01594171cba97faf94ee9c8b9db2a49c 331 SUPERFAMILY SSF53098 171 317 8.19E-24 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_19310 01594171cba97faf94ee9c8b9db2a49c 331 ProSitePatterns PS01043 Transposases, IS30 family, signature. 265 281 - T 14-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 A4R43_19310 01594171cba97faf94ee9c8b9db2a49c 331 Pfam PF13936 Helix-turn-helix domain 1 40 2.4E-15 T 14-10-2018 IPR025246 Transposase IS30-like HTH domain A4R43_19310 01594171cba97faf94ee9c8b9db2a49c 331 Pfam PF00665 Integrase core domain 171 278 2.4E-10 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_40295 01594171cba97faf94ee9c8b9db2a49c 331 SUPERFAMILY SSF53098 171 317 8.19E-24 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_40295 01594171cba97faf94ee9c8b9db2a49c 331 ProSitePatterns PS01043 Transposases, IS30 family, signature. 265 281 - T 14-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 A4R43_40295 01594171cba97faf94ee9c8b9db2a49c 331 Pfam PF13936 Helix-turn-helix domain 1 40 2.4E-15 T 14-10-2018 IPR025246 Transposase IS30-like HTH domain A4R43_40295 01594171cba97faf94ee9c8b9db2a49c 331 Pfam PF00665 Integrase core domain 171 278 2.4E-10 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_19190 01594171cba97faf94ee9c8b9db2a49c 331 SUPERFAMILY SSF53098 171 317 8.19E-24 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_19190 01594171cba97faf94ee9c8b9db2a49c 331 ProSitePatterns PS01043 Transposases, IS30 family, signature. 265 281 - T 14-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 A4R43_19190 01594171cba97faf94ee9c8b9db2a49c 331 Pfam PF13936 Helix-turn-helix domain 1 40 2.4E-15 T 14-10-2018 IPR025246 Transposase IS30-like HTH domain A4R43_19190 01594171cba97faf94ee9c8b9db2a49c 331 Pfam PF00665 Integrase core domain 171 278 2.4E-10 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_05325 01594171cba97faf94ee9c8b9db2a49c 331 SUPERFAMILY SSF53098 171 317 8.19E-24 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_05325 01594171cba97faf94ee9c8b9db2a49c 331 ProSitePatterns PS01043 Transposases, IS30 family, signature. 265 281 - T 14-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 A4R43_05325 01594171cba97faf94ee9c8b9db2a49c 331 Pfam PF13936 Helix-turn-helix domain 1 40 2.4E-15 T 14-10-2018 IPR025246 Transposase IS30-like HTH domain A4R43_05325 01594171cba97faf94ee9c8b9db2a49c 331 Pfam PF00665 Integrase core domain 171 278 2.4E-10 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 Gene3D G3DSA:2.60.120.260 3 172 7.6E-58 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 SUPERFAMILY SSF49785 9 170 2.3E-54 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 PIRSF PIRSF016516 262 329 2.2E-12 T 14-10-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 PIRSF PIRSF016516 3 270 8.6E-82 T 14-10-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 TIGRFAM TIGR02961 allantoicase: allantoicase 12 316 8.1E-114 T 14-10-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 SUPERFAMILY SSF49785 180 318 2.64E-38 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 Pfam PF03561 Allantoicase repeat 20 167 5.0E-44 T 14-10-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 Pfam PF03561 Allantoicase repeat 189 316 2.0E-34 T 14-10-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 Hamap MF_00813 Probable allantoicase [alc]. 1 319 42.768 T 14-10-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 A4R43_18545 fdcd4cac182e4a4b94e3d41d6a9bb1e4 332 Gene3D G3DSA:2.60.120.260 180 316 1.1E-39 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_25860 d2ef6d9fb1c7acd6ee6f2edb9464dfb0 547 Gene3D G3DSA:3.30.300.30 433 535 5.3E-32 T 14-10-2018 A4R43_25860 d2ef6d9fb1c7acd6ee6f2edb9464dfb0 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 522 1.0E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_25860 d2ef6d9fb1c7acd6ee6f2edb9464dfb0 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_25860 d2ef6d9fb1c7acd6ee6f2edb9464dfb0 547 SUPERFAMILY SSF56801 19 534 2.35E-165 T 14-10-2018 A4R43_25860 d2ef6d9fb1c7acd6ee6f2edb9464dfb0 547 Gene3D G3DSA:3.40.50.12780 17 432 4.8E-125 T 14-10-2018 A4R43_25860 d2ef6d9fb1c7acd6ee6f2edb9464dfb0 547 Pfam PF00501 AMP-binding enzyme 26 437 3.4E-114 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_07480 0db2d26085ac22e99f2a82928f76596c 295 Pfam PF04230 Polysaccharide pyruvyl transferase 183 222 4.4E-9 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase A4R43_17885 79cda865d47ccdf50363dc576b551803 333 SUPERFAMILY SSF102114 35 296 1.57E-61 T 14-10-2018 A4R43_17885 79cda865d47ccdf50363dc576b551803 333 Gene3D G3DSA:3.20.20.70 75 258 7.7E-15 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17885 79cda865d47ccdf50363dc576b551803 333 TIGRFAM TIGR00510 lipA: lipoyl synthase 17 303 4.7E-98 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_17885 79cda865d47ccdf50363dc576b551803 333 PIRSF PIRSF005963 2 318 3.0E-120 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_17885 79cda865d47ccdf50363dc576b551803 333 SMART SM00729 71 277 2.9E-14 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_17885 79cda865d47ccdf50363dc576b551803 333 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 140.346 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_17885 79cda865d47ccdf50363dc576b551803 333 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 4.0E-7 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_17885 79cda865d47ccdf50363dc576b551803 333 Pfam PF04055 Radical SAM superfamily 81 234 7.2E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_18340 13bd5a02eb314190fa7b36388607adfe 85 Pfam PF10939 Protein of unknown function (DUF2631) 2 66 1.3E-30 T 14-10-2018 IPR024341 Protein of unknown function DUF2631 A4R43_18340 13bd5a02eb314190fa7b36388607adfe 85 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 11 60 4.0E-7 T 14-10-2018 IPR024341 Protein of unknown function DUF2631 A4R43_17845 be3c2a1cf8efad30d3ec32199b699a99 156 Pfam PF12840 Helix-turn-helix domain 70 129 6.4E-10 T 14-10-2018 A4R43_17845 be3c2a1cf8efad30d3ec32199b699a99 156 SUPERFAMILY SSF46785 68 133 1.91E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_17845 be3c2a1cf8efad30d3ec32199b699a99 156 SMART SM00418 70 144 4.7E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_17845 be3c2a1cf8efad30d3ec32199b699a99 156 Gene3D G3DSA:1.10.10.10 68 154 1.7E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21815 2ea2832cff911c3649e955723e321392 253 Pfam PF12679 ABC-2 family transporter protein 57 251 5.3E-7 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 9.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 9.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 9.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 Gene3D G3DSA:3.40.50.720 1 259 5.1E-67 T 14-10-2018 A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 Pfam PF00106 short chain dehydrogenase 11 196 2.0E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 SUPERFAMILY SSF51735 7 250 6.41E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22900 b013cbdfffa767880ec0b20ae371bcfa 284 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 189 2.5E-4 T 14-10-2018 A4R43_22890 bf2973828f70ddf1abe1bb7005d590fe 93 Gene3D G3DSA:3.40.1620.10 5 46 3.4E-7 T 14-10-2018 A4R43_22890 bf2973828f70ddf1abe1bb7005d590fe 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 9 72 3.4E-10 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4R43_22890 bf2973828f70ddf1abe1bb7005d590fe 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 11 59 1.9E-7 T 14-10-2018 A4R43_22890 bf2973828f70ddf1abe1bb7005d590fe 93 SUPERFAMILY SSF143120 10 73 2.09E-10 T 14-10-2018 IPR036165 YefM-like superfamily A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 94 6.7E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 Pfam PF03704 Bacterial transcriptional activator domain 101 242 6.5E-39 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 Gene3D G3DSA:1.10.10.10 1 95 5.4E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 PRINTS PR00364 Disease resistance protein signature 364 378 4.8E-8 T 14-10-2018 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 PRINTS PR00364 Disease resistance protein signature 285 300 4.8E-8 T 14-10-2018 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 PRINTS PR00364 Disease resistance protein signature 458 472 4.8E-8 T 14-10-2018 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 Gene3D G3DSA:1.25.40.10 99 265 1.1E-48 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 SUPERFAMILY SSF48452 856 1004 4.61E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 Pfam PF00931 NB-ARC domain 283 469 8.2E-7 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 Gene3D G3DSA:1.25.40.10 851 1015 1.2E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 SUPERFAMILY SSF46894 3 94 4.82E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 SUPERFAMILY SSF48452 97 260 5.08E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 SUPERFAMILY SSF48452 720 889 2.09E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 SMART SM01043 101 243 4.5E-50 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 SUPERFAMILY SSF52540 253 522 9.0E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38360 dc21953d89187e36ae63a4be4aeca08f 1059 SMART SM00862 16 94 7.0E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 SMART SM00862 15 88 2.1E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 SMART SM01043 95 238 1.1E-42 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 SUPERFAMILY SSF52540 259 461 8.3E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 SUPERFAMILY SSF48452 90 248 4.17E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 Pfam PF00931 NB-ARC domain 280 457 1.4E-7 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 SUPERFAMILY SSF46894 2 88 7.09E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 Pfam PF03704 Bacterial transcriptional activator domain 95 238 2.1E-38 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 Gene3D G3DSA:1.10.10.10 1 91 2.4E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 77 3.2E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 SMART SM00382 278 415 0.0024 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 Gene3D G3DSA:1.25.40.10 93 262 3.3E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 PRINTS PR00364 Disease resistance protein signature 358 372 4.5E-9 T 14-10-2018 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 PRINTS PR00364 Disease resistance protein signature 281 296 4.5E-9 T 14-10-2018 A4R43_03675 bb061df759677f82b7a50b57442b1f5d 486 PRINTS PR00364 Disease resistance protein signature 443 457 4.5E-9 T 14-10-2018 A4R43_27810 d840e587394bf7cd9dcab0a506c8bfb3 278 Pfam PF13391 HNH endonuclease 188 242 1.2E-7 T 14-10-2018 IPR003615 HNH nuclease A4R43_27810 d840e587394bf7cd9dcab0a506c8bfb3 278 Gene3D G3DSA:2.30.280.10 2 144 1.6E-51 T 14-10-2018 IPR036987 SRA-YDG superfamily A4R43_27810 d840e587394bf7cd9dcab0a506c8bfb3 278 SUPERFAMILY SSF88697 4 142 7.7E-46 T 14-10-2018 IPR015947 PUA-like superfamily A4R43_27810 d840e587394bf7cd9dcab0a506c8bfb3 278 Pfam PF02182 SAD/SRA domain 4 141 2.8E-44 T 14-10-2018 IPR003105 SRA-YDG A4R43_27810 d840e587394bf7cd9dcab0a506c8bfb3 278 SMART SM00466 3 145 9.5E-48 T 14-10-2018 IPR003105 SRA-YDG A4R43_31155 1d16b593df4f9bf56f50f186c607ec76 470 Pfam PF01546 Peptidase family M20/M25/M40 95 465 3.4E-23 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_31155 1d16b593df4f9bf56f50f186c607ec76 470 Pfam PF07687 Peptidase dimerisation domain 207 362 3.7E-8 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_31155 1d16b593df4f9bf56f50f186c607ec76 470 SUPERFAMILY SSF53187 11 467 3.71E-44 T 14-10-2018 A4R43_31155 1d16b593df4f9bf56f50f186c607ec76 470 Gene3D G3DSA:3.40.630.10 351 470 4.3E-17 T 14-10-2018 A4R43_31155 1d16b593df4f9bf56f50f186c607ec76 470 Gene3D G3DSA:3.40.630.10 1 227 2.4E-49 T 14-10-2018 A4R43_20985 9f7ca859fe6d2ec9d68a5213571cc426 149 Pfam PF08281 Sigma-70, region 4 85 135 4.7E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_20985 9f7ca859fe6d2ec9d68a5213571cc426 149 Gene3D G3DSA:1.10.1740.10 1 74 1.2E-12 T 14-10-2018 A4R43_20985 9f7ca859fe6d2ec9d68a5213571cc426 149 Pfam PF04542 Sigma-70 region 2 1 60 4.9E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_20985 9f7ca859fe6d2ec9d68a5213571cc426 149 Gene3D G3DSA:1.10.10.10 82 140 2.9E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20985 9f7ca859fe6d2ec9d68a5213571cc426 149 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 137 1.2E-16 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_20985 9f7ca859fe6d2ec9d68a5213571cc426 149 SUPERFAMILY SSF88659 77 139 4.3E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_20985 9f7ca859fe6d2ec9d68a5213571cc426 149 SUPERFAMILY SSF88946 2 67 4.71E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08995 35dadfcc2ef09170dc2f5f4b7498f341 275 PIRSF PIRSF015853 1 272 1.3E-90 T 14-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A4R43_08995 35dadfcc2ef09170dc2f5f4b7498f341 275 Gene3D G3DSA:3.40.50.10780 1 212 1.4E-84 T 14-10-2018 IPR027476 D-aminopeptidase, N-terminal A4R43_08995 35dadfcc2ef09170dc2f5f4b7498f341 275 SUPERFAMILY SSF63992 1 267 7.85E-84 T 14-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily A4R43_08995 35dadfcc2ef09170dc2f5f4b7498f341 275 Pfam PF04951 D-aminopeptidase 1 260 1.4E-91 T 14-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A4R43_08995 35dadfcc2ef09170dc2f5f4b7498f341 275 Gene3D G3DSA:3.30.1360.130 118 259 1.4E-84 T 14-10-2018 A4R43_03240 ab0943613a210cebd807c5f9e2d5b78f 310 SUPERFAMILY SSF51197 4 306 6.8E-55 T 14-10-2018 A4R43_03240 ab0943613a210cebd807c5f9e2d5b78f 310 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 156 267 1.4E-11 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 A4R43_03240 ab0943613a210cebd807c5f9e2d5b78f 310 Gene3D G3DSA:2.60.120.330 2 309 5.6E-81 T 14-10-2018 IPR027443 Isopenicillin N synthase-like A4R43_01910 60b41da17cf79e989adf64c2bbf3a7f8 287 Pfam PF12697 Alpha/beta hydrolase family 61 281 9.4E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_01910 60b41da17cf79e989adf64c2bbf3a7f8 287 Gene3D G3DSA:3.40.50.1820 10 285 5.0E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01910 60b41da17cf79e989adf64c2bbf3a7f8 287 SUPERFAMILY SSF53474 32 282 1.02E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25755 c2c86ba95a94e88df99caa616a36d8f5 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 4.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25755 c2c86ba95a94e88df99caa616a36d8f5 200 Gene3D G3DSA:1.10.357.10 10 200 1.8E-32 T 14-10-2018 A4R43_25755 c2c86ba95a94e88df99caa616a36d8f5 200 SUPERFAMILY SSF46689 10 83 5.64E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25755 c2c86ba95a94e88df99caa616a36d8f5 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25755 c2c86ba95a94e88df99caa616a36d8f5 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25755 c2c86ba95a94e88df99caa616a36d8f5 200 SUPERFAMILY SSF48498 87 197 1.0E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_25755 c2c86ba95a94e88df99caa616a36d8f5 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_03270 8cd20281ddb1fb470f3eaabbb05066ed 302 Pfam PF04909 Amidohydrolase 135 299 8.9E-18 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_03270 8cd20281ddb1fb470f3eaabbb05066ed 302 Gene3D G3DSA:3.20.20.140 1 300 3.9E-32 T 14-10-2018 A4R43_03270 8cd20281ddb1fb470f3eaabbb05066ed 302 SUPERFAMILY SSF51556 2 299 3.64E-21 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_06585 2ad67c9a6fb0b3a59035ca33fe67e6b1 222 Gene3D G3DSA:1.20.120.530 83 219 6.5E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_06585 2ad67c9a6fb0b3a59035ca33fe67e6b1 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 59 4.0E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06585 2ad67c9a6fb0b3a59035ca33fe67e6b1 222 SUPERFAMILY SSF48008 86 219 1.1E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_06585 2ad67c9a6fb0b3a59035ca33fe67e6b1 222 SMART SM00895 88 212 9.6E-19 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06585 2ad67c9a6fb0b3a59035ca33fe67e6b1 222 Gene3D G3DSA:1.10.10.10 1 69 2.4E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06585 2ad67c9a6fb0b3a59035ca33fe67e6b1 222 SUPERFAMILY SSF46785 3 63 4.28E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06585 2ad67c9a6fb0b3a59035ca33fe67e6b1 222 Pfam PF07729 FCD domain 89 209 2.1E-24 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06585 2ad67c9a6fb0b3a59035ca33fe67e6b1 222 SMART SM00345 1 59 0.0024 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05390 2492e8706db1ba7e9015eecd4f220b7b 153 Gene3D G3DSA:3.30.530.20 2 140 6.6E-36 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_05390 2492e8706db1ba7e9015eecd4f220b7b 153 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 128 6.2E-20 T 14-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 A4R43_05390 2492e8706db1ba7e9015eecd4f220b7b 153 SUPERFAMILY SSF55961 3 142 2.94E-27 T 14-10-2018 A4R43_32650 c67b174d684cb1418f23ab5c0368e271 396 Gene3D G3DSA:1.25.40.10 196 390 4.9E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32650 c67b174d684cb1418f23ab5c0368e271 396 SUPERFAMILY SSF88659 98 158 5.79E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_32650 c67b174d684cb1418f23ab5c0368e271 396 Pfam PF04542 Sigma-70 region 2 9 73 4.9E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_32650 c67b174d684cb1418f23ab5c0368e271 396 Pfam PF08281 Sigma-70, region 4 105 156 2.2E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_32650 c67b174d684cb1418f23ab5c0368e271 396 Gene3D G3DSA:1.10.1740.10 5 70 6.6E-10 T 14-10-2018 A4R43_32650 c67b174d684cb1418f23ab5c0368e271 396 Gene3D G3DSA:1.10.10.10 110 160 2.8E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32650 c67b174d684cb1418f23ab5c0368e271 396 SUPERFAMILY SSF88946 8 87 2.12E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_32650 c67b174d684cb1418f23ab5c0368e271 396 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 158 1.0E-15 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 Pfam PF02355 Protein export membrane protein 362 537 7.8E-10 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 291 524 1.7E-61 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 547 39.038 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 Gene3D G3DSA:1.20.1640.10 354 544 2.2E-8 T 14-10-2018 A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 40 532 2.9E-117 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 Gene3D G3DSA:3.30.1360.200 217 353 8.9E-30 T 14-10-2018 A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 SUPERFAMILY SSF82866 338 537 8.89E-30 T 14-10-2018 A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 Pfam PF07549 SecD/SecF GG Motif 39 54 9.9E-4 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4R43_04340 0286aef32d8030a16874c7ccd7327cb8 572 Gene3D G3DSA:3.30.70.3400 40 125 2.1E-15 T 14-10-2018 A4R43_30905 8ac46aff6889f9cbb05f687192f6b443 434 Gene3D G3DSA:2.30.40.10 10 424 1.9E-120 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_30905 8ac46aff6889f9cbb05f687192f6b443 434 SUPERFAMILY SSF51556 58 354 5.38E-85 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_30905 8ac46aff6889f9cbb05f687192f6b443 434 Gene3D G3DSA:3.20.20.140 59 348 1.9E-120 T 14-10-2018 A4R43_30905 8ac46aff6889f9cbb05f687192f6b443 434 SUPERFAMILY SSF51338 320 433 1.23E-15 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_30905 8ac46aff6889f9cbb05f687192f6b443 434 Pfam PF01979 Amidohydrolase family 55 408 2.1E-61 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 485 494 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 608 620 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 181 196 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 375 389 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 8 18 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 196 209 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 327 343 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 235 257 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 624 640 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR01159 DNA gyrase subunit B signature 389 409 5.2E-72 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 SUPERFAMILY SSF56719 409 650 1.33E-81 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4R43_30405 28153568d31ab0881053d56db78f535a 655 Pfam PF00204 DNA gyrase B 236 405 4.5E-62 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_30405 28153568d31ab0881053d56db78f535a 655 Gene3D G3DSA:3.40.50.670 413 655 1.1E-97 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 501 517 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 539 551 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 283 296 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 519 536 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 72 85 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 115 129 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 435 449 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 587 603 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 PRINTS PR00418 DNA topoisomerase II family signature 37 52 1.0E-68 T 14-10-2018 A4R43_30405 28153568d31ab0881053d56db78f535a 655 SUPERFAMILY SSF55874 8 214 1.28E-68 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30405 28153568d31ab0881053d56db78f535a 655 Gene3D G3DSA:3.30.565.10 4 219 1.2E-83 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30405 28153568d31ab0881053d56db78f535a 655 SMART SM00433 37 648 0.0 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_30405 28153568d31ab0881053d56db78f535a 655 ProSitePatterns PS00177 DNA topoisomerase II signature. 437 445 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4R43_30405 28153568d31ab0881053d56db78f535a 655 Gene3D G3DSA:3.30.230.10 235 407 2.3E-73 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_30405 28153568d31ab0881053d56db78f535a 655 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 655 91.502 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 SUPERFAMILY SSF54211 236 406 2.09E-59 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_30405 28153568d31ab0881053d56db78f535a 655 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 586 643 7.1E-27 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 Pfam PF01751 Toprim domain 434 544 5.3E-16 T 14-10-2018 IPR006171 TOPRIM domain A4R43_30405 28153568d31ab0881053d56db78f535a 655 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 655 7.9E-286 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4R43_30405 28153568d31ab0881053d56db78f535a 655 SMART SM00387 33 176 1.5E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_30405 28153568d31ab0881053d56db78f535a 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 175 6.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_22525 c814e0c91cb340dc4f6521f0fdde6fc3 281 Gene3D G3DSA:3.30.450.180 109 279 2.4E-8 T 14-10-2018 A4R43_22525 c814e0c91cb340dc4f6521f0fdde6fc3 281 Gene3D G3DSA:1.10.260.40 29 104 3.6E-8 T 14-10-2018 A4R43_22525 c814e0c91cb340dc4f6521f0fdde6fc3 281 SMART SM00530 15 88 8.1E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_22525 c814e0c91cb340dc4f6521f0fdde6fc3 281 Pfam PF13560 Helix-turn-helix domain 11 91 1.1E-15 T 14-10-2018 A4R43_22525 c814e0c91cb340dc4f6521f0fdde6fc3 281 SUPERFAMILY SSF47413 34 87 2.51E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_11670 39b734561acee48b0a356f282575562b 398 Gene3D G3DSA:1.10.150.20 169 237 7.2E-21 T 14-10-2018 A4R43_11670 39b734561acee48b0a356f282575562b 398 Pfam PF11799 impB/mucB/samB family C-terminal domain 241 347 2.4E-17 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_11670 39b734561acee48b0a356f282575562b 398 Gene3D G3DSA:3.30.70.270 72 165 9.4E-27 T 14-10-2018 A4R43_11670 39b734561acee48b0a356f282575562b 398 Gene3D G3DSA:2.30.40.20 16 71 9.5E-24 T 14-10-2018 A4R43_11670 39b734561acee48b0a356f282575562b 398 SUPERFAMILY SSF56672 6 235 3.29E-75 T 14-10-2018 A4R43_11670 39b734561acee48b0a356f282575562b 398 SUPERFAMILY SSF100879 243 355 8.32E-18 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_11670 39b734561acee48b0a356f282575562b 398 Gene3D G3DSA:3.30.1490.100 241 350 1.5E-18 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_11670 39b734561acee48b0a356f282575562b 398 Hamap MF_01113 DNA polymerase IV [dinB]. 6 353 33.022 T 14-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4R43_11670 39b734561acee48b0a356f282575562b 398 Pfam PF00817 impB/mucB/samB family 13 153 1.7E-45 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_11670 39b734561acee48b0a356f282575562b 398 Pfam PF11798 IMS family HHH motif 166 197 1.2E-8 T 14-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4R43_02675 30e69c8df99426e0c96b6641df265929 390 Gene3D G3DSA:3.40.50.2000 170 370 1.1E-63 T 14-10-2018 A4R43_02675 30e69c8df99426e0c96b6641df265929 390 Pfam PF00534 Glycosyl transferases group 1 182 345 2.1E-17 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_02675 30e69c8df99426e0c96b6641df265929 390 SUPERFAMILY SSF53756 13 379 5.1E-43 T 14-10-2018 A4R43_02675 30e69c8df99426e0c96b6641df265929 390 Pfam PF13439 Glycosyltransferase Family 4 18 128 3.6E-12 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_02675 30e69c8df99426e0c96b6641df265929 390 Gene3D G3DSA:3.40.50.2000 10 376 1.1E-63 T 14-10-2018 A4R43_41420 3afd590f1168eb1d47a292e555deff05 660 Gene3D G3DSA:3.30.450.330 299 639 7.9E-102 T 14-10-2018 A4R43_41420 3afd590f1168eb1d47a292e555deff05 660 SUPERFAMILY SSF56601 298 645 6.52E-90 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_41420 3afd590f1168eb1d47a292e555deff05 660 Pfam PF00905 Penicillin binding protein transpeptidase domain 323 635 3.5E-83 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4R43_41420 3afd590f1168eb1d47a292e555deff05 660 Gene3D G3DSA:3.90.1310.30 95 297 6.0E-31 T 14-10-2018 A4R43_41420 3afd590f1168eb1d47a292e555deff05 660 Gene3D G3DSA:3.40.710.10 359 552 7.9E-102 T 14-10-2018 A4R43_41420 3afd590f1168eb1d47a292e555deff05 660 SUPERFAMILY SSF56519 100 297 4.71E-28 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A4R43_41420 3afd590f1168eb1d47a292e555deff05 660 Pfam PF03717 Penicillin-binding Protein dimerisation domain 102 277 6.8E-17 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 181 5.4E-4 T 14-10-2018 A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 4.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 239 1.8E-63 T 14-10-2018 A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 Gene3D G3DSA:3.40.50.720 1 242 1.7E-85 T 14-10-2018 A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 SUPERFAMILY SSF51735 4 242 4.0E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_36915 b0f59e6cbc3bd59d7588812e7fc6deb0 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 80 91 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 143 158 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 286 313 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 314 329 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 269 280 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 188 210 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 335 344 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 126 142 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 PRINTS PR00359 B-class P450 signature 344 355 1.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 Gene3D G3DSA:1.10.630.10 2 402 5.2E-113 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 Pfam PF00067 Cytochrome P450 146 379 3.4E-18 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_12595 7002050184f17b394600922dd7f01885 403 SUPERFAMILY SSF48264 18 398 8.12E-85 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_12135 a4ee867bd06fdd4176b62593a23bd376 269 Pfam PF05368 NmrA-like family 1 203 1.7E-11 T 14-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 A4R43_12135 a4ee867bd06fdd4176b62593a23bd376 269 SUPERFAMILY SSF51735 1 261 1.44E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_12135 a4ee867bd06fdd4176b62593a23bd376 269 Gene3D G3DSA:3.90.25.10 122 251 3.0E-55 T 14-10-2018 A4R43_12135 a4ee867bd06fdd4176b62593a23bd376 269 Gene3D G3DSA:3.40.50.720 2 250 3.0E-55 T 14-10-2018 A4R43_20170 4719e1240cc603e2413debf59b9098e4 161 Gene3D G3DSA:3.40.30.10 2 161 1.1E-57 T 14-10-2018 A4R43_20170 4719e1240cc603e2413debf59b9098e4 161 PRINTS PR01011 Glutathione peroxidase family signature 21 38 2.1E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4R43_20170 4719e1240cc603e2413debf59b9098e4 161 PRINTS PR01011 Glutathione peroxidase family signature 56 72 2.1E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4R43_20170 4719e1240cc603e2413debf59b9098e4 161 PRINTS PR01011 Glutathione peroxidase family signature 122 131 2.1E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4R43_20170 4719e1240cc603e2413debf59b9098e4 161 Pfam PF00255 Glutathione peroxidase 5 109 7.5E-39 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4R43_20170 4719e1240cc603e2413debf59b9098e4 161 PIRSF PIRSF000303 1 161 4.6E-59 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4R43_20170 4719e1240cc603e2413debf59b9098e4 161 SUPERFAMILY SSF52833 3 160 4.54E-52 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_19240 528fd6771cacafd9e01aea6fc8ec1f52 296 Gene3D G3DSA:3.20.20.70 1 296 2.3E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_19240 528fd6771cacafd9e01aea6fc8ec1f52 296 SUPERFAMILY SSF51569 29 290 1.03E-31 T 14-10-2018 A4R43_06410 d618958e6e36bdc3a1e48e9f998d7154 300 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 41 270 2.5E-29 T 14-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 A4R43_39805 d221f6cff8dbcf6ca8641cb364450415 370 Pfam PF00079 Serpin (serine protease inhibitor) 15 367 8.4E-77 T 14-10-2018 IPR023796 Serpin domain A4R43_39805 d221f6cff8dbcf6ca8641cb364450415 370 SUPERFAMILY SSF56574 13 367 1.13E-82 T 14-10-2018 IPR036186 Serpin superfamily A4R43_39805 d221f6cff8dbcf6ca8641cb364450415 370 Gene3D G3DSA:3.30.497.10 22 329 2.9E-83 T 14-10-2018 A4R43_39805 d221f6cff8dbcf6ca8641cb364450415 370 SMART SM00093 13 367 3.0E-62 T 14-10-2018 IPR023796 Serpin domain A4R43_39805 d221f6cff8dbcf6ca8641cb364450415 370 ProSitePatterns PS00284 Serpins signature. 340 350 - T 14-10-2018 IPR023795 Serpin, conserved site A4R43_39805 d221f6cff8dbcf6ca8641cb364450415 370 Gene3D G3DSA:2.30.39.10 166 367 2.9E-83 T 14-10-2018 A4R43_00980 c39aad44986853972cfcec3518c2a6bb 147 SUPERFAMILY SSF46955 3 120 2.53E-21 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_00980 c39aad44986853972cfcec3518c2a6bb 147 Pfam PF13411 MerR HTH family regulatory protein 3 69 2.3E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00980 c39aad44986853972cfcec3518c2a6bb 147 Gene3D G3DSA:1.10.1660.10 1 121 1.3E-22 T 14-10-2018 A4R43_00980 c39aad44986853972cfcec3518c2a6bb 147 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 4.6E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00980 c39aad44986853972cfcec3518c2a6bb 147 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 4.6E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00980 c39aad44986853972cfcec3518c2a6bb 147 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 4.6E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00980 c39aad44986853972cfcec3518c2a6bb 147 SMART SM00422 3 72 5.6E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 Gene3D G3DSA:3.40.50.720 4 235 1.8E-64 T 14-10-2018 A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.9E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.9E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.9E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.9E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 1.9E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 232 6.0E-47 T 14-10-2018 A4R43_13425 efec04a40a85ce72e003c2290e8bf3e7 239 SUPERFAMILY SSF51735 1 233 4.38E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 Gene3D G3DSA:1.10.10.60 1 62 8.8E-26 T 14-10-2018 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 4.2E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 Gene3D G3DSA:1.10.357.10 63 210 1.2E-35 T 14-10-2018 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 69 209 6.8E-30 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 SUPERFAMILY SSF48498 69 213 1.33E-33 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 SUPERFAMILY SSF46689 4 63 4.66E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 PRINTS PR00400 Tetracycline repressor protein signature 95 118 2.1E-17 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 PRINTS PR00400 Tetracycline repressor protein signature 20 43 2.1E-17 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 PRINTS PR00400 Tetracycline repressor protein signature 75 94 2.1E-17 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_34655 e20c7e146b0ef4b6fa557bc0ab46cbb9 218 PRINTS PR00400 Tetracycline repressor protein signature 131 150 2.1E-17 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_31510 ddcf263bf0d1cbf1c4cc55afda9c7755 211 PRINTS PR00988 Uridine kinase signature 20 37 4.2E-7 T 14-10-2018 A4R43_31510 ddcf263bf0d1cbf1c4cc55afda9c7755 211 PRINTS PR00988 Uridine kinase signature 49 60 4.2E-7 T 14-10-2018 A4R43_31510 ddcf263bf0d1cbf1c4cc55afda9c7755 211 PRINTS PR00988 Uridine kinase signature 189 202 4.2E-7 T 14-10-2018 A4R43_31510 ddcf263bf0d1cbf1c4cc55afda9c7755 211 PRINTS PR00988 Uridine kinase signature 155 165 4.2E-7 T 14-10-2018 A4R43_31510 ddcf263bf0d1cbf1c4cc55afda9c7755 211 SUPERFAMILY SSF52540 17 202 2.74E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31510 ddcf263bf0d1cbf1c4cc55afda9c7755 211 Gene3D G3DSA:3.40.50.300 4 204 3.3E-52 T 14-10-2018 A4R43_12765 a039f5977ed3d290c16b1a4c23bbca24 90 SUPERFAMILY SSF54909 7 72 6.44E-7 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_12765 a039f5977ed3d290c16b1a4c23bbca24 90 Gene3D G3DSA:3.30.70.100 1 88 1.1E-6 T 14-10-2018 A4R43_26650 2bec6c035bbf426c0ad64201e19be47b 423 Pfam PF04286 Protein of unknown function (DUF445) 37 119 3.5E-9 T 14-10-2018 IPR007383 Protein of unknown function DUF445 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 SMART SM00840 338 400 7.8E-13 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 310 2.0E-119 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 7.3E-27 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 7.3E-27 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 7.3E-27 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 7.3E-27 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 Gene3D G3DSA:3.40.50.620 1 302 2.2E-120 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 Pfam PF09190 DALR domain 338 391 1.7E-9 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 SUPERFAMILY SSF47323 314 458 5.89E-33 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 Gene3D G3DSA:1.20.120.640 303 459 5.4E-34 T 14-10-2018 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 457 1.7E-133 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 SUPERFAMILY SSF52374 4 308 2.23E-87 T 14-10-2018 A4R43_26595 0a896421e25f08d20e8741420d6ffd00 461 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 459 35.146 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 89 112 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 SUPERFAMILY SSF51905 3 518 1.81E-70 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 Gene3D G3DSA:3.30.410.40 157 458 2.0E-150 T 14-10-2018 A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 Gene3D G3DSA:3.50.50.60 6 517 2.0E-150 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 PIRSF PIRSF000137 1 320 1.7E-67 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 PIRSF PIRSF000137 319 521 4.0E-36 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 264 278 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 SUPERFAMILY SSF54373 300 464 3.83E-15 T 14-10-2018 A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 Pfam PF05199 GMC oxidoreductase 377 516 1.3E-34 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_01615 293b7ed0fe6abbfd4a7a915e76450f2f 522 Pfam PF00732 GMC oxidoreductase 6 305 5.1E-59 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_28480 9e565086b32ed2bcbe65b27c10b31040 222 SUPERFAMILY SSF51206 9 129 3.4E-25 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like A4R43_28480 9e565086b32ed2bcbe65b27c10b31040 222 Pfam PF13545 Crp-like helix-turn-helix domain 141 213 1.7E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4R43_28480 9e565086b32ed2bcbe65b27c10b31040 222 SMART SM00100 3 124 1.3E-14 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_28480 9e565086b32ed2bcbe65b27c10b31040 222 Pfam PF00027 Cyclic nucleotide-binding domain 21 109 4.7E-15 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_28480 9e565086b32ed2bcbe65b27c10b31040 222 SUPERFAMILY SSF46785 138 216 3.57E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_28480 9e565086b32ed2bcbe65b27c10b31040 222 Gene3D G3DSA:1.10.10.10 139 220 3.7E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28480 9e565086b32ed2bcbe65b27c10b31040 222 Gene3D G3DSA:2.60.120.10 1 138 1.7E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_24300 6a303649dc2330c419b92eb75449a583 801 SUPERFAMILY SSF51445 262 577 1.22E-56 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_24300 6a303649dc2330c419b92eb75449a583 801 SUPERFAMILY SSF49785 29 151 9.5E-25 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_24300 6a303649dc2330c419b92eb75449a583 801 Gene3D G3DSA:2.60.40.10 691 799 1.0E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_24300 6a303649dc2330c419b92eb75449a583 801 Pfam PF00703 Glycosyl hydrolases family 2 157 265 7.3E-19 T 14-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 A4R43_24300 6a303649dc2330c419b92eb75449a583 801 Pfam PF16355 Domain of unknown function (DUF4982) 624 678 1.1E-18 T 14-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4R43_24300 6a303649dc2330c419b92eb75449a583 801 Gene3D G3DSA:2.60.40.10 612 687 4.6E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_24300 6a303649dc2330c419b92eb75449a583 801 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 58 149 1.5E-10 T 14-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4R43_24300 6a303649dc2330c419b92eb75449a583 801 SUPERFAMILY SSF49303 159 265 2.68E-20 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily A4R43_24300 6a303649dc2330c419b92eb75449a583 801 PRINTS PR00132 Glycosyl hydrolase family 2 signature 277 291 1.7E-5 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 A4R43_24300 6a303649dc2330c419b92eb75449a583 801 PRINTS PR00132 Glycosyl hydrolase family 2 signature 308 326 1.7E-5 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 A4R43_24300 6a303649dc2330c419b92eb75449a583 801 PRINTS PR00132 Glycosyl hydrolase family 2 signature 378 393 1.7E-5 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 A4R43_24300 6a303649dc2330c419b92eb75449a583 801 Gene3D G3DSA:2.60.120.260 2 151 1.5E-28 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_24300 6a303649dc2330c419b92eb75449a583 801 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 275 434 1.5E-19 T 14-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 A4R43_24300 6a303649dc2330c419b92eb75449a583 801 Gene3D G3DSA:2.60.40.10 152 265 2.1E-28 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_23805 7fed7bd5113180e52d5f6a35a89f2999 473 SUPERFAMILY SSF103473 5 459 2.35E-59 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_23805 7fed7bd5113180e52d5f6a35a89f2999 473 Gene3D G3DSA:1.20.1250.20 266 463 3.4E-17 T 14-10-2018 A4R43_23805 7fed7bd5113180e52d5f6a35a89f2999 473 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 88 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_23805 7fed7bd5113180e52d5f6a35a89f2999 473 Gene3D G3DSA:1.20.1720.10 19 227 1.0E-37 T 14-10-2018 A4R43_23805 7fed7bd5113180e52d5f6a35a89f2999 473 Pfam PF07690 Major Facilitator Superfamily 25 415 6.9E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_39830 7f88600ac1976db647e2b881c7174986 305 SMART SM00062 66 288 1.1E-47 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_39830 7f88600ac1976db647e2b881c7174986 305 Gene3D G3DSA:3.40.190.10 156 246 1.4E-58 T 14-10-2018 A4R43_39830 7f88600ac1976db647e2b881c7174986 305 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 69 277 9.7E-43 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_39830 7f88600ac1976db647e2b881c7174986 305 SUPERFAMILY SSF53850 46 279 8.01E-48 T 14-10-2018 A4R43_39830 7f88600ac1976db647e2b881c7174986 305 Gene3D G3DSA:3.40.190.10 60 278 1.4E-58 T 14-10-2018 A4R43_15245 57f2de3e9361df40dbdcd6ed9d258c8f 115 SMART SM00363 1 63 6.8E-4 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_15245 57f2de3e9361df40dbdcd6ed9d258c8f 115 Pfam PF01479 S4 domain 2 45 7.2E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_15245 57f2de3e9361df40dbdcd6ed9d258c8f 115 Gene3D G3DSA:3.10.290.10 1 96 2.3E-27 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4R43_15245 57f2de3e9361df40dbdcd6ed9d258c8f 115 SUPERFAMILY SSF55174 1 80 2.88E-20 T 14-10-2018 A4R43_15245 57f2de3e9361df40dbdcd6ed9d258c8f 115 PIRSF PIRSF016821 1 115 1.6E-43 T 14-10-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 A4R43_17310 ca80612cac176a0e49878bd2bf7be73c 379 Gene3D G3DSA:1.20.1250.20 1 376 4.0E-22 T 14-10-2018 A4R43_17310 ca80612cac176a0e49878bd2bf7be73c 379 SUPERFAMILY SSF103473 5 373 1.57E-27 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_17310 ca80612cac176a0e49878bd2bf7be73c 379 Pfam PF07690 Major Facilitator Superfamily 12 329 1.3E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_04810 2658d81de2f48776f02399d6974741a5 223 SUPERFAMILY SSF51366 1 216 1.11E-64 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4R43_04810 2658d81de2f48776f02399d6974741a5 223 Pfam PF00834 Ribulose-phosphate 3 epimerase family 2 201 1.4E-75 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4R43_04810 2658d81de2f48776f02399d6974741a5 223 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 32 46 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4R43_04810 2658d81de2f48776f02399d6974741a5 223 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 1 214 6.8E-79 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4R43_04810 2658d81de2f48776f02399d6974741a5 223 Gene3D G3DSA:3.20.20.70 1 219 4.7E-79 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_04810 2658d81de2f48776f02399d6974741a5 223 PIRSF PIRSF001461 1 223 4.2E-88 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4R43_04810 2658d81de2f48776f02399d6974741a5 223 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 134 156 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 ProSitePatterns PS00438 Catalase proximal active site signature. 42 58 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 Pfam PF00199 Catalase 6 384 1.8E-186 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 SUPERFAMILY SSF56634 4 478 2.88E-201 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 SMART SM01060 6 387 3.2E-278 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 PRINTS PR00067 Catalase signature 81 99 2.5E-69 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 PRINTS PR00067 Catalase signature 102 119 2.5E-69 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 PRINTS PR00067 Catalase signature 121 139 2.5E-69 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 PRINTS PR00067 Catalase signature 318 344 2.5E-69 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 PRINTS PR00067 Catalase signature 19 42 2.5E-69 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 PRINTS PR00067 Catalase signature 286 313 2.5E-69 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 PIRSF PIRSF038928 1 480 5.6E-234 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 331 339 - T 14-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 Pfam PF06628 Catalase-related immune-responsive 416 477 2.6E-18 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4R43_27305 ae190da23500f20b9335c0ddb0ae3c65 480 Gene3D G3DSA:2.40.180.10 1 480 4.0E-221 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A4R43_31075 7aa6806f8a3e9b253c0d64c9c19705af 345 SUPERFAMILY SSF51695 30 330 1.05E-58 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A4R43_31075 7aa6806f8a3e9b253c0d64c9c19705af 345 Gene3D G3DSA:3.20.20.190 19 338 3.5E-95 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A4R43_31075 7aa6806f8a3e9b253c0d64c9c19705af 345 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 35 325 3.3E-37 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A4R43_07090 d53665585a49f20ac4c435a0988df8b6 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 1.8E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_07090 d53665585a49f20ac4c435a0988df8b6 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 1.8E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_07090 d53665585a49f20ac4c435a0988df8b6 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 114 130 1.8E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_07090 d53665585a49f20ac4c435a0988df8b6 305 SUPERFAMILY SSF51569 4 296 3.14E-77 T 14-10-2018 A4R43_07090 d53665585a49f20ac4c435a0988df8b6 305 PIRSF PIRSF001365 3 305 3.6E-73 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_07090 d53665585a49f20ac4c435a0988df8b6 305 Gene3D G3DSA:3.20.20.70 2 298 2.6E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_07090 d53665585a49f20ac4c435a0988df8b6 305 SMART SM01130 6 298 1.4E-91 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_07090 d53665585a49f20ac4c435a0988df8b6 305 Pfam PF00701 Dihydrodipicolinate synthetase family 9 295 6.2E-47 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 Gene3D G3DSA:3.30.870.10 334 518 6.9E-74 T 14-10-2018 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 SUPERFAMILY SSF143724 126 328 4.12E-68 T 14-10-2018 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 SUPERFAMILY SSF56024 520 694 8.3E-61 T 14-10-2018 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 22 693 3.6E-252 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 Gene3D G3DSA:3.30.870.10 519 699 2.1E-58 T 14-10-2018 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 SUPERFAMILY SSF140356 20 122 8.24E-35 T 14-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 SUPERFAMILY SSF56024 343 516 7.85E-57 T 14-10-2018 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 Pfam PF13090 Polyphosphate kinase C-terminal domain 348 692 3.0E-148 T 14-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 Hamap MF_00347 Polyphosphate kinase [ppk]. 20 698 28.607 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 Pfam PF02503 Polyphosphate kinase middle domain 141 337 3.9E-71 T 14-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 PIRSF PIRSF015589 5 700 3.7E-272 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 Pfam PF13089 Polyphosphate kinase N-terminal domain 23 129 3.6E-35 T 14-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A4R43_19570 a8624b93c1087ce1a25336943788324e 700 Gene3D G3DSA:3.30.1840.10 16 328 3.0E-115 T 14-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 A4R43_19275 24adcf00373960332434f2446a8c9e88 284 Gene3D G3DSA:3.30.390.50 177 283 2.1E-28 T 14-10-2018 A4R43_19275 24adcf00373960332434f2446a8c9e88 284 SMART SM01092 180 281 2.8E-31 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_19275 24adcf00373960332434f2446a8c9e88 284 Gene3D G3DSA:3.30.43.10 1 54 5.4E-22 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_19275 24adcf00373960332434f2446a8c9e88 284 SUPERFAMILY SSF56176 2 174 8.59E-56 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_19275 24adcf00373960332434f2446a8c9e88 284 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 3.0E-50 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4R43_19275 24adcf00373960332434f2446a8c9e88 284 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 181 280 6.1E-22 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_19275 24adcf00373960332434f2446a8c9e88 284 SUPERFAMILY SSF55447 178 282 4.58E-29 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily A4R43_19275 24adcf00373960332434f2446a8c9e88 284 Gene3D G3DSA:3.30.465.10 60 173 1.3E-40 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_13195 a57c85a5fb9d8d352097edda17950258 208 SUPERFAMILY SSF48613 51 172 1.85E-5 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_13195 a57c85a5fb9d8d352097edda17950258 208 ProDom PD209215 WITH SIMILARITIES RP592 6 203 9.0E-20 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 Gene3D G3DSA:3.50.50.60 150 270 1.9E-121 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 2.0E-35 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 466 8.9E-170 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 SUPERFAMILY SSF55424 343 465 1.68E-38 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PIRSF PIRSF000350 1 462 6.5E-86 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.1E-63 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 Gene3D G3DSA:3.50.50.60 5 332 1.9E-121 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 Gene3D G3DSA:3.30.390.30 345 466 1.8E-44 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 SUPERFAMILY SSF51905 2 336 2.69E-62 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 1.8E-34 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 1.8E-34 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 1.8E-34 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.8E-34 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 1.8E-34 T 14-10-2018 A4R43_18940 505b3a22c467a416bb622937b21d18f5 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 327 5.4E-67 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_02200 3c55856f6c80c340b9ae6c7af0d174ee 597 SUPERFAMILY SSF90123 31 335 1.31E-54 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_02200 3c55856f6c80c340b9ae6c7af0d174ee 597 Pfam PF00005 ABC transporter 368 517 1.9E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_02200 3c55856f6c80c340b9ae6c7af0d174ee 597 SUPERFAMILY SSF52540 346 586 9.53E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_02200 3c55856f6c80c340b9ae6c7af0d174ee 597 SMART SM00382 377 563 2.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_02200 3c55856f6c80c340b9ae6c7af0d174ee 597 Pfam PF00664 ABC transporter transmembrane region 34 306 1.1E-32 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_02200 3c55856f6c80c340b9ae6c7af0d174ee 597 Gene3D G3DSA:1.20.1560.10 10 339 7.2E-57 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_02200 3c55856f6c80c340b9ae6c7af0d174ee 597 Gene3D G3DSA:3.40.50.300 345 593 3.2E-83 T 14-10-2018 A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 SUPERFAMILY SSF54909 61 144 1.61E-14 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 SMART SM00344 1 108 1.1E-35 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 Gene3D G3DSA:1.10.10.10 1 51 1.4E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.7E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.7E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.7E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 Gene3D G3DSA:3.30.70.920 52 141 1.1E-17 T 14-10-2018 A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 1.8E-12 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 SUPERFAMILY SSF46785 1 61 3.57E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_33250 b992bcdba0bc7b3583e28e5a875f10c6 148 Pfam PF13404 AsnC-type helix-turn-helix domain 1 41 6.1E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_01440 9c3c49f8f9d3df9405c4a94d7eeb44a7 793 Pfam PF13560 Helix-turn-helix domain 4 67 2.3E-15 T 14-10-2018 A4R43_01440 9c3c49f8f9d3df9405c4a94d7eeb44a7 793 Pfam PF05729 NACHT domain 193 347 2.8E-7 T 14-10-2018 IPR007111 NACHT nucleoside triphosphatase A4R43_01440 9c3c49f8f9d3df9405c4a94d7eeb44a7 793 SMART SM00530 8 64 1.5E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_01440 9c3c49f8f9d3df9405c4a94d7eeb44a7 793 Gene3D G3DSA:1.10.260.40 2 75 7.1E-15 T 14-10-2018 A4R43_01440 9c3c49f8f9d3df9405c4a94d7eeb44a7 793 SUPERFAMILY SSF47413 3 63 2.62E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 Gene3D G3DSA:3.40.50.200 128 403 1.7E-92 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 Pfam PF05922 Peptidase inhibitor I9 51 125 1.9E-9 T 14-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 208 6.0E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 6.0E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 PRINTS PR00723 Subtilisin serine protease family (S8) signature 157 176 6.0E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 199 209 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 SUPERFAMILY SSF54897 50 125 3.74E-10 T 14-10-2018 A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 347 357 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 Gene3D G3DSA:3.30.70.80 42 126 1.3E-15 T 14-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 162 173 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 Pfam PF00082 Subtilase family 164 384 3.9E-38 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_19035 e6afe3e6b46f083cefa2e0f95d1c8194 403 SUPERFAMILY SSF52743 130 391 1.14E-77 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_25450 2c1b4835790677d864fc300d93983719 384 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 113 378 2.2E-87 T 14-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A4R43_25450 2c1b4835790677d864fc300d93983719 384 PRINTS PR00095 Anthranilate synthase component I signature 313 327 7.9E-5 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_25450 2c1b4835790677d864fc300d93983719 384 PRINTS PR00095 Anthranilate synthase component I signature 328 342 7.9E-5 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_25450 2c1b4835790677d864fc300d93983719 384 PRINTS PR00095 Anthranilate synthase component I signature 221 234 7.9E-5 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_25450 2c1b4835790677d864fc300d93983719 384 Gene3D G3DSA:3.60.120.10 7 383 6.3E-115 T 14-10-2018 IPR005801 ADC synthase GO:0009058 A4R43_25450 2c1b4835790677d864fc300d93983719 384 Pfam PF00425 chorismate binding enzyme 119 371 8.8E-74 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A4R43_25450 2c1b4835790677d864fc300d93983719 384 SUPERFAMILY SSF56322 59 381 1.18E-89 T 14-10-2018 IPR005801 ADC synthase GO:0009058 A4R43_13875 b4511d4882dfc77154cc63782d1bb85e 313 SUPERFAMILY SSF53098 119 305 8.35E-37 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_13875 b4511d4882dfc77154cc63782d1bb85e 313 Gene3D G3DSA:3.30.420.10 154 306 1.5E-27 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_13875 b4511d4882dfc77154cc63782d1bb85e 313 SUPERFAMILY SSF46689 6 96 1.52E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13875 b4511d4882dfc77154cc63782d1bb85e 313 Pfam PF00665 Integrase core domain 118 264 1.4E-36 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_13875 b4511d4882dfc77154cc63782d1bb85e 313 Pfam PF13011 leucine-zipper of insertion element IS481 1 67 2.5E-16 T 14-10-2018 IPR024967 DNA-binding domain, IS481-type A4R43_07180 2ac5311de8bfb3e642637090cfa68550 601 Gene3D G3DSA:2.60.40.10 28 114 6.9E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_07180 2ac5311de8bfb3e642637090cfa68550 601 SUPERFAMILY SSF69318 133 573 1.83E-14 T 14-10-2018 A4R43_03105 4dfebc81610419905d7897941937f965 335 SUPERFAMILY SSF81606 147 329 4.84E-12 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03105 4dfebc81610419905d7897941937f965 335 Gene3D G3DSA:3.60.40.10 145 329 2.6E-29 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03105 4dfebc81610419905d7897941937f965 335 SMART SM00331 144 331 7.7E-4 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03105 4dfebc81610419905d7897941937f965 335 SUPERFAMILY SSF55874 36 129 7.78E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03105 4dfebc81610419905d7897941937f965 335 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 173 294 2.3E-5 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03105 4dfebc81610419905d7897941937f965 335 Gene3D G3DSA:3.30.565.10 10 136 2.1E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_34810 5b4123d0ff3b51bb14d27d8242ae6623 354 SUPERFAMILY SSF52540 60 305 2.06E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34810 5b4123d0ff3b51bb14d27d8242ae6623 354 Gene3D G3DSA:3.40.50.300 68 349 6.5E-115 T 14-10-2018 A4R43_34810 5b4123d0ff3b51bb14d27d8242ae6623 354 Gene3D G3DSA:2.40.50.140 1 49 3.7E-9 T 14-10-2018 A4R43_34810 5b4123d0ff3b51bb14d27d8242ae6623 354 SMART SM00382 104 271 5.6E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_34810 5b4123d0ff3b51bb14d27d8242ae6623 354 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 93 297 5.2E-23 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_34810 5b4123d0ff3b51bb14d27d8242ae6623 354 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 351 154.958 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4R43_34810 5b4123d0ff3b51bb14d27d8242ae6623 354 Pfam PF07497 Rho termination factor, RNA-binding domain 4 46 7.6E-9 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 A4R43_41280 de899f57b8ca045becee5c354fa24caa 449 Gene3D G3DSA:3.10.105.10 235 350 8.8E-9 T 14-10-2018 A4R43_41280 de899f57b8ca045becee5c354fa24caa 449 Gene3D G3DSA:3.10.105.10 372 423 1.3E-5 T 14-10-2018 A4R43_41280 de899f57b8ca045becee5c354fa24caa 449 SUPERFAMILY SSF53850 29 440 5.97E-51 T 14-10-2018 A4R43_41280 de899f57b8ca045becee5c354fa24caa 449 Gene3D G3DSA:3.40.190.10 10 229 1.1E-24 T 14-10-2018 A4R43_41280 de899f57b8ca045becee5c354fa24caa 449 Gene3D G3DSA:3.40.190.10 424 434 1.3E-5 T 14-10-2018 A4R43_41280 de899f57b8ca045becee5c354fa24caa 449 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 335 8.9E-30 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_41280 de899f57b8ca045becee5c354fa24caa 449 PIRSF PIRSF002741 357 447 1.0E-4 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_41280 de899f57b8ca045becee5c354fa24caa 449 PIRSF PIRSF002741 51 339 3.6E-25 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 SUPERFAMILY SSF50129 3 186 2.59E-55 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 Gene3D G3DSA:3.40.50.720 167 305 2.9E-117 T 14-10-2018 A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 SUPERFAMILY SSF50129 311 361 9.42E-7 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 SUPERFAMILY SSF51735 155 327 1.86E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 SMART SM00829 17 362 7.4E-5 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 362 2.8E-202 T 14-10-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase MetaCyc: PWY-7908 A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 3.2E-28 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 Pfam PF00107 Zinc-binding dehydrogenase 190 322 4.2E-30 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_09660 9c67b0fdbe3020443a965f96b699c892 362 Gene3D G3DSA:3.90.180.10 11 359 2.9E-117 T 14-10-2018 A4R43_30820 490d9d0518fd889b27be630fd9fafd9c 773 SUPERFAMILY SSF56601 339 691 4.51E-71 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_30820 490d9d0518fd889b27be630fd9fafd9c 773 Gene3D G3DSA:1.10.3810.10 122 311 3.1E-56 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_30820 490d9d0518fd889b27be630fd9fafd9c 773 SUPERFAMILY SSF53955 117 311 2.17E-54 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_30820 490d9d0518fd889b27be630fd9fafd9c 773 Pfam PF00905 Penicillin binding protein transpeptidase domain 388 649 6.8E-31 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4R43_30820 490d9d0518fd889b27be630fd9fafd9c 773 Pfam PF00912 Transglycosylase 134 295 6.8E-51 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_30820 490d9d0518fd889b27be630fd9fafd9c 773 Gene3D G3DSA:3.40.710.10 327 708 1.2E-98 T 14-10-2018 A4R43_32430 103828714daecaf35b2cd290206758b6 370 SUPERFAMILY SSF55874 254 364 1.9E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_32430 103828714daecaf35b2cd290206758b6 370 Gene3D G3DSA:3.30.565.10 247 369 2.4E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_32430 103828714daecaf35b2cd290206758b6 370 Pfam PF07730 Histidine kinase 180 247 1.5E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_11605 a6ba44dfe36598cbb6cc4193c1f9fbee 420 Pfam PF00652 Ricin-type beta-trefoil lectin domain 296 416 1.8E-29 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_11605 a6ba44dfe36598cbb6cc4193c1f9fbee 420 SUPERFAMILY SSF49899 44 288 2.19E-70 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_11605 a6ba44dfe36598cbb6cc4193c1f9fbee 420 Gene3D G3DSA:2.80.10.50 294 383 2.0E-30 T 14-10-2018 A4R43_11605 a6ba44dfe36598cbb6cc4193c1f9fbee 420 Pfam PF00722 Glycosyl hydrolases family 16 80 286 1.2E-42 T 14-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 A4R43_11605 a6ba44dfe36598cbb6cc4193c1f9fbee 420 Gene3D G3DSA:2.80.10.50 384 419 5.4E-12 T 14-10-2018 A4R43_11605 a6ba44dfe36598cbb6cc4193c1f9fbee 420 SUPERFAMILY SSF50370 296 417 3.93E-40 T 14-10-2018 IPR035992 Ricin B-like lectins A4R43_11605 a6ba44dfe36598cbb6cc4193c1f9fbee 420 SMART SM00458 294 419 3.9E-30 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_11605 a6ba44dfe36598cbb6cc4193c1f9fbee 420 Gene3D G3DSA:2.60.120.200 47 293 5.0E-84 T 14-10-2018 A4R43_33015 ff73517f19037983d658b70d897b55a3 291 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 288 21.255 T 14-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4R43_33015 ff73517f19037983d658b70d897b55a3 291 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 287 1.5E-89 T 14-10-2018 A4R43_33015 ff73517f19037983d658b70d897b55a3 291 Pfam PF01040 UbiA prenyltransferase family 20 252 5.7E-36 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A4R43_33015 ff73517f19037983d658b70d897b55a3 291 PIRSF PIRSF005355 1 291 1.9E-85 T 14-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 A4R43_31540 9eb60635eab6439b9a53a85dd802a10b 275 Gene3D G3DSA:2.40.128.110 99 271 6.4E-45 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily A4R43_31540 9eb60635eab6439b9a53a85dd802a10b 275 SUPERFAMILY SSF49452 3 80 5.1E-6 T 14-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A4R43_31540 9eb60635eab6439b9a53a85dd802a10b 275 SMART SM00867 99 267 1.9E-56 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4R43_31540 9eb60635eab6439b9a53a85dd802a10b 275 Pfam PF04264 YceI-like domain 100 266 5.2E-35 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4R43_31540 9eb60635eab6439b9a53a85dd802a10b 275 SUPERFAMILY SSF101874 98 269 3.53E-47 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 40 560 2.1E-279 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 383 408 - T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 SUPERFAMILY SSF52242 559 724 1.57E-57 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 Pfam PF02310 B12 binding domain 598 713 6.2E-16 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 Gene3D G3DSA:3.20.20.240 40 555 2.2E-240 T 14-10-2018 A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 SUPERFAMILY SSF51703 18 555 3.4E-220 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 Gene3D G3DSA:3.40.50.280 559 724 6.3E-56 T 14-10-2018 A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 595 724 1.2E-62 T 14-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_34970 040545b8eb5a1e29aac720c3ad4d5895 726 Pfam PF01642 Methylmalonyl-CoA mutase 41 553 1.9E-234 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 127 150 3.0E-41 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 3.0E-41 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 3.0E-41 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 3.0E-41 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 78 94 3.0E-41 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 3.0E-41 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 Gene3D G3DSA:3.40.190.80 138 262 4.6E-28 T 14-10-2018 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 Pfam PF00459 Inositol monophosphatase family 31 259 7.8E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 Gene3D G3DSA:3.30.540.10 3 137 6.2E-33 T 14-10-2018 A4R43_20745 fe4ebe96037971478bee1062a7ff4f9d 263 SUPERFAMILY SSF56655 6 259 1.83E-64 T 14-10-2018 A4R43_00315 85a003108d694130173372fb749975de 250 SUPERFAMILY SSF52096 3 246 1.76E-68 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_00315 85a003108d694130173372fb749975de 250 Gene3D G3DSA:3.90.226.10 2 249 5.0E-68 T 14-10-2018 A4R43_00315 85a003108d694130173372fb749975de 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 245 3.2E-47 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_19355 6b74f4a6967fa4f3cb1cd8f42ed5c435 264 Pfam PF01614 Bacterial transcriptional regulator 125 251 3.0E-39 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_19355 6b74f4a6967fa4f3cb1cd8f42ed5c435 264 SUPERFAMILY SSF55781 74 253 1.11E-53 T 14-10-2018 A4R43_19355 6b74f4a6967fa4f3cb1cd8f42ed5c435 264 SUPERFAMILY SSF46785 10 82 3.47E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19355 6b74f4a6967fa4f3cb1cd8f42ed5c435 264 Gene3D G3DSA:3.30.450.40 79 256 2.9E-66 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_19355 6b74f4a6967fa4f3cb1cd8f42ed5c435 264 Pfam PF09339 IclR helix-turn-helix domain 12 63 1.8E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_19355 6b74f4a6967fa4f3cb1cd8f42ed5c435 264 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 8 253 6.3E-105 T 14-10-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 A4R43_19355 6b74f4a6967fa4f3cb1cd8f42ed5c435 264 Gene3D G3DSA:1.10.10.10 4 78 1.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19355 6b74f4a6967fa4f3cb1cd8f42ed5c435 264 SMART SM00346 10 98 1.1E-36 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_08245 27e66712434282bb3768bb0c11f83179 140 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 93 4.8E-10 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_08245 27e66712434282bb3768bb0c11f83179 140 SUPERFAMILY SSF50475 4 136 8.04E-22 T 14-10-2018 A4R43_08245 27e66712434282bb3768bb0c11f83179 140 Gene3D G3DSA:2.30.110.10 1 135 2.0E-22 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_18925 a2c9c520f1e5a1c8cef810c1add71ac3 325 Gene3D G3DSA:3.30.565.10 182 320 2.4E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_18925 a2c9c520f1e5a1c8cef810c1add71ac3 325 SUPERFAMILY SSF55874 178 317 7.2E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_18925 a2c9c520f1e5a1c8cef810c1add71ac3 325 SMART SM00387 215 320 7.2E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_18925 a2c9c520f1e5a1c8cef810c1add71ac3 325 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 220 317 1.5E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_18925 a2c9c520f1e5a1c8cef810c1add71ac3 325 Pfam PF06580 Histidine kinase 122 200 8.6E-21 T 14-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A4R43_40280 8e6e609dbc5b771a0cbffe1d7864b483 324 SUPERFAMILY SSF53807 45 319 1.41E-41 T 14-10-2018 A4R43_40280 8e6e609dbc5b771a0cbffe1d7864b483 324 Pfam PF01497 Periplasmic binding protein 49 298 4.4E-27 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_40280 8e6e609dbc5b771a0cbffe1d7864b483 324 Gene3D G3DSA:3.40.50.1980 27 143 3.6E-12 T 14-10-2018 A4R43_40280 8e6e609dbc5b771a0cbffe1d7864b483 324 Gene3D G3DSA:3.40.50.1980 154 323 5.2E-55 T 14-10-2018 A4R43_34590 1ac6d6178191012e79057fefe84aa63c 121 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 3 119 1.5E-32 T 14-10-2018 IPR018699 Protein of unknown function DUF2203 A4R43_34590 1ac6d6178191012e79057fefe84aa63c 121 PIRSF PIRSF016498 1 121 5.6E-20 T 14-10-2018 IPR018699 Protein of unknown function DUF2203 A4R43_09460 125d8f79201dd041d49cf41e44b3e290 258 Pfam PF01614 Bacterial transcriptional regulator 137 248 3.0E-16 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_09460 125d8f79201dd041d49cf41e44b3e290 258 Gene3D G3DSA:1.10.10.10 6 78 7.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09460 125d8f79201dd041d49cf41e44b3e290 258 SMART SM00346 18 107 2.1E-25 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_09460 125d8f79201dd041d49cf41e44b3e290 258 Pfam PF09339 IclR helix-turn-helix domain 21 70 1.0E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_09460 125d8f79201dd041d49cf41e44b3e290 258 Gene3D G3DSA:3.30.450.40 86 256 4.6E-31 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_09460 125d8f79201dd041d49cf41e44b3e290 258 SUPERFAMILY SSF46785 20 90 4.38E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09460 125d8f79201dd041d49cf41e44b3e290 258 SUPERFAMILY SSF55781 75 252 1.05E-31 T 14-10-2018 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 343 166.584 T 14-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 SUPERFAMILY SSF51569 3 270 4.94E-59 T 14-10-2018 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 Gene3D G3DSA:1.10.8.60 275 346 8.6E-32 T 14-10-2018 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 SUPERFAMILY SSF89000 288 337 1.88E-17 T 14-10-2018 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 Pfam PF07836 DmpG-like communication domain 273 334 2.7E-30 T 14-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 Pfam PF00682 HMGL-like 6 264 1.2E-49 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 275 333 6.0E-16 T 14-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 5 336 1.4E-144 T 14-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 A4R43_11390 11705c7dda72f2217eae8bb20bdc90fd 347 Gene3D G3DSA:3.20.20.70 2 268 1.0E-82 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_03205 e0a48c3376108565ce35d1dcd54ca315 313 SUPERFAMILY SSF51197 3 307 1.65E-64 T 14-10-2018 A4R43_03205 e0a48c3376108565ce35d1dcd54ca315 313 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 157 268 1.6E-13 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 A4R43_03205 e0a48c3376108565ce35d1dcd54ca315 313 Gene3D G3DSA:2.60.120.330 2 312 2.8E-94 T 14-10-2018 IPR027443 Isopenicillin N synthase-like A4R43_03205 e0a48c3376108565ce35d1dcd54ca315 313 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 6 108 9.4E-8 T 14-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain A4R43_02480 0ac6dda7aae3d065f1823bc4df7e117f 260 Pfam PF03704 Bacterial transcriptional activator domain 100 245 5.4E-36 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_02480 0ac6dda7aae3d065f1823bc4df7e117f 260 Gene3D G3DSA:1.25.40.10 98 256 1.0E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_02480 0ac6dda7aae3d065f1823bc4df7e117f 260 SUPERFAMILY SSF48452 96 252 6.58E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_02480 0ac6dda7aae3d065f1823bc4df7e117f 260 Gene3D G3DSA:1.10.10.10 1 95 5.0E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02480 0ac6dda7aae3d065f1823bc4df7e117f 260 SUPERFAMILY SSF46894 2 93 1.67E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_02480 0ac6dda7aae3d065f1823bc4df7e117f 260 SMART SM01043 100 245 9.2E-37 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_02480 0ac6dda7aae3d065f1823bc4df7e117f 260 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 92 5.9E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_02480 0ac6dda7aae3d065f1823bc4df7e117f 260 SMART SM00862 15 93 5.3E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 Gene3D G3DSA:1.10.10.10 9 83 1.4E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 SUPERFAMILY SSF46785 13 87 1.7E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 6.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 6.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 Gene3D G3DSA:3.40.640.10 100 449 2.1E-81 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 SUPERFAMILY SSF53383 78 456 1.66E-68 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 1.5E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 Pfam PF00155 Aminotransferase class I and II 145 399 9.3E-10 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_19540 e47e76feb1824dbf9bbed6cf924f4fd0 466 SMART SM00345 24 83 3.6E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_29235 3ea567d2a165147e9f539142a6e3f81d 876 Gene3D G3DSA:3.40.50.300 411 506 2.4E-5 T 14-10-2018 A4R43_29235 3ea567d2a165147e9f539142a6e3f81d 876 Pfam PF04851 Type III restriction enzyme, res subunit 23 149 2.6E-7 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4R43_29235 3ea567d2a165147e9f539142a6e3f81d 876 Gene3D G3DSA:3.40.50.300 18 174 1.2E-11 T 14-10-2018 A4R43_29235 3ea567d2a165147e9f539142a6e3f81d 876 SUPERFAMILY SSF52540 11 153 9.34E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10690 9675126273392b722a9f82bca09e4e0d 406 Gene3D G3DSA:3.40.630.30 135 297 4.0E-38 T 14-10-2018 A4R43_10690 9675126273392b722a9f82bca09e4e0d 406 Gene3D G3DSA:3.30.1050.10 303 397 4.6E-20 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_10690 9675126273392b722a9f82bca09e4e0d 406 SUPERFAMILY SSF55718 305 406 1.18E-17 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_10690 9675126273392b722a9f82bca09e4e0d 406 Gene3D G3DSA:3.40.630.30 1 133 1.3E-30 T 14-10-2018 A4R43_10690 9675126273392b722a9f82bca09e4e0d 406 Pfam PF13530 Sterol carrier protein domain 180 402 6.2E-49 T 14-10-2018 IPR025559 Enhanced intracellular survival protein domain A4R43_10690 9675126273392b722a9f82bca09e4e0d 406 Pfam PF13527 Acetyltransferase (GNAT) domain 6 131 7.2E-24 T 14-10-2018 A4R43_10690 9675126273392b722a9f82bca09e4e0d 406 Hamap MF_01812 N-acetyltransferase Eis [eis]. 3 406 31.715 T 14-10-2018 IPR022902 N-acetyltransferase Eis A4R43_10690 9675126273392b722a9f82bca09e4e0d 406 SUPERFAMILY SSF55729 5 304 3.27E-47 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_39605 98bbb48c2717fa838346027570fde4d5 260 Gene3D G3DSA:3.60.110.10 1 260 2.2E-95 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_39605 98bbb48c2717fa838346027570fde4d5 260 Pfam PF00795 Carbon-nitrogen hydrolase 3 240 1.5E-57 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_39605 98bbb48c2717fa838346027570fde4d5 260 SUPERFAMILY SSF56317 3 257 8.24E-71 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_13855 dac1175ab65a3c61151a4305f2ec64eb 142 Pfam PF14042 Domain of unknown function (DUF4247) 21 141 1.4E-18 T 14-10-2018 IPR025341 Protein of unknown function DUF4247 A4R43_13855 dac1175ab65a3c61151a4305f2ec64eb 142 ProDom PD031728 MEMBRANE PROBABLE RV2599/MT2674 PRECURSOR TRANSMEMBRANE B1177_F3_123 SIGNAL 6 113 0.004 T 14-10-2018 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 Pfam PF00196 Bacterial regulatory proteins, luxR family 760 811 3.5E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 791 803 3.3E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 761 775 3.3E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 775 791 3.3E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 ProSitePatterns PS00622 LuxR-type HTH domain signature. 775 802 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 SMART SM00421 758 815 3.2E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 SUPERFAMILY SSF52540 5 170 7.57E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 SUPERFAMILY SSF46894 749 813 5.1E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 Pfam PF13191 AAA ATPase domain 2 156 9.3E-17 T 14-10-2018 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 Gene3D G3DSA:1.25.40.10 493 744 5.1E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32260 7c4444fa5b10642459075cfce0c0ca78 832 Gene3D G3DSA:1.10.10.10 756 815 7.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22825 2419dc867a339db3691fc08d5b38344e 517 Gene3D G3DSA:3.40.50.970 319 517 7.9E-46 T 14-10-2018 A4R43_22825 2419dc867a339db3691fc08d5b38344e 517 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 165 3.2E-33 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_22825 2419dc867a339db3691fc08d5b38344e 517 SUPERFAMILY SSF52518 334 515 7.51E-43 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_22825 2419dc867a339db3691fc08d5b38344e 517 Gene3D G3DSA:3.40.50.970 1 170 2.2E-39 T 14-10-2018 A4R43_22825 2419dc867a339db3691fc08d5b38344e 517 SUPERFAMILY SSF52518 1 179 2.9E-36 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_22825 2419dc867a339db3691fc08d5b38344e 517 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 374 510 4.5E-28 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_16055 7359a0b2606243057bc866a7eadfa880 557 Pfam PF00890 FAD binding domain 6 532 2.1E-89 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16055 7359a0b2606243057bc866a7eadfa880 557 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.2E-6 T 14-10-2018 A4R43_16055 7359a0b2606243057bc866a7eadfa880 557 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 258 2.2E-6 T 14-10-2018 A4R43_16055 7359a0b2606243057bc866a7eadfa880 557 Gene3D G3DSA:3.90.700.10 326 481 2.1E-162 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16055 7359a0b2606243057bc866a7eadfa880 557 SUPERFAMILY SSF56425 308 486 1.96E-35 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16055 7359a0b2606243057bc866a7eadfa880 557 SUPERFAMILY SSF51905 3 551 1.07E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_16055 7359a0b2606243057bc866a7eadfa880 557 Gene3D G3DSA:3.50.50.60 4 544 2.1E-162 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_06270 c540c589d418cd21f6b061235264eec3 157 Pfam PF03073 TspO/MBR family 17 154 2.6E-40 T 14-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 A4R43_06270 c540c589d418cd21f6b061235264eec3 157 Gene3D G3DSA:1.20.1260.100 7 157 1.1E-42 T 14-10-2018 IPR038330 TspO/MBR-related superfamily A4R43_06270 c540c589d418cd21f6b061235264eec3 157 PIRSF PIRSF005859 4 157 2.1E-43 T 14-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 A4R43_33800 4f5be17b84fb19fcea08e15d53cf053e 457 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 369 1.1E-59 T 14-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A4R43_33800 4f5be17b84fb19fcea08e15d53cf053e 457 SUPERFAMILY SSF53649 2 455 5.56E-75 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A4R43_33800 4f5be17b84fb19fcea08e15d53cf053e 457 Gene3D G3DSA:3.30.1360.110 272 350 2.2E-7 T 14-10-2018 IPR023116 Phosphonoacetate hydrolase, insert domain superfamily KEGG: 00440+3.11.1.2 A4R43_33800 4f5be17b84fb19fcea08e15d53cf053e 457 Gene3D G3DSA:3.40.720.10 1 266 2.1E-39 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 SUPERFAMILY SSF53795 247 606 6.87E-159 T 14-10-2018 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 PIRSF PIRSF001348 3 607 4.3E-285 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 Gene3D G3DSA:2.170.8.10 57 401 1.3E-277 T 14-10-2018 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 247 606 3.7E-174 T 14-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 SUPERFAMILY SSF68923 12 246 2.72E-94 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 271 279 - T 14-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 Gene3D G3DSA:3.90.228.20 247 605 1.3E-277 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 607 50.321 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 22 243 4.4E-100 T 14-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_30995 4af6bfdc04fb809b29c91c67f67fcf36 607 Gene3D G3DSA:3.40.449.10 22 246 1.3E-277 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4R43_39100 ad732be27b22980bd3d5511b4fc66664 224 Gene3D G3DSA:1.10.3630.10 1 215 2.5E-35 T 14-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily A4R43_39100 ad732be27b22980bd3d5511b4fc66664 224 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 3 204 3.0E-47 T 14-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 A4R43_11375 43e165a3893e1e9443f5f09f05e38137 341 Gene3D G3DSA:3.20.20.30 1 339 8.0E-83 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_11375 43e165a3893e1e9443f5f09f05e38137 341 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 326 1.1E-145 T 14-10-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c A4R43_11375 43e165a3893e1e9443f5f09f05e38137 341 Pfam PF00296 Luciferase-like monooxygenase 18 322 2.9E-77 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_11375 43e165a3893e1e9443f5f09f05e38137 341 SUPERFAMILY SSF51679 1 329 9.68E-67 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_23895 371bf666de3fb876c512f6923818ef36 318 SUPERFAMILY SSF53067 133 317 2.59E-36 T 14-10-2018 A4R43_23895 371bf666de3fb876c512f6923818ef36 318 Gene3D G3DSA:3.30.420.40 1 127 7.6E-47 T 14-10-2018 A4R43_23895 371bf666de3fb876c512f6923818ef36 318 Pfam PF02541 Ppx/GppA phosphatase family 25 314 6.7E-69 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4R43_23895 371bf666de3fb876c512f6923818ef36 318 Gene3D G3DSA:3.30.420.150 128 318 1.3E-60 T 14-10-2018 A4R43_23895 371bf666de3fb876c512f6923818ef36 318 SUPERFAMILY SSF53067 3 127 2.46E-34 T 14-10-2018 A4R43_03065 8d5388a77106e4084afecfe40bc9187a 319 Gene3D G3DSA:3.40.50.720 7 312 3.2E-68 T 14-10-2018 A4R43_03065 8d5388a77106e4084afecfe40bc9187a 319 Pfam PF00106 short chain dehydrogenase 16 218 1.0E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03065 8d5388a77106e4084afecfe40bc9187a 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 8.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03065 8d5388a77106e4084afecfe40bc9187a 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 8.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03065 8d5388a77106e4084afecfe40bc9187a 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 8.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03065 8d5388a77106e4084afecfe40bc9187a 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 8.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03065 8d5388a77106e4084afecfe40bc9187a 319 SUPERFAMILY SSF51735 13 264 1.36E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_10685 9c03fca521dcaf225b4e1ad79418805c 315 SMART SM00279 188 223 2.5E-12 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A4R43_10685 9c03fca521dcaf225b4e1ad79418805c 315 SUPERFAMILY SSF47807 191 303 4.19E-20 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A4R43_10685 9c03fca521dcaf225b4e1ad79418805c 315 SMART SM00475 3 280 1.6E-72 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A4R43_10685 9c03fca521dcaf225b4e1ad79418805c 315 SUPERFAMILY SSF88723 4 153 7.06E-36 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_10685 9c03fca521dcaf225b4e1ad79418805c 315 Gene3D G3DSA:3.40.50.1010 6 294 6.0E-64 T 14-10-2018 A4R43_10685 9c03fca521dcaf225b4e1ad79418805c 315 Gene3D G3DSA:1.10.150.20 185 265 6.0E-64 T 14-10-2018 A4R43_10685 9c03fca521dcaf225b4e1ad79418805c 315 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 180 2.0E-45 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A4R43_10685 9c03fca521dcaf225b4e1ad79418805c 315 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 190 276 9.2E-20 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 A4R43_35490 e4e9807ec97502c0b006c5624d33ea0b 178 SUPERFAMILY SSF55811 47 175 4.74E-20 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_35490 e4e9807ec97502c0b006c5624d33ea0b 178 Gene3D G3DSA:3.90.79.10 4 178 9.8E-35 T 14-10-2018 A4R43_35490 e4e9807ec97502c0b006c5624d33ea0b 178 Pfam PF00293 NUDIX domain 47 160 2.7E-11 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_01370 1e5626d2a1993dbc923b461124e5a23e 178 Gene3D G3DSA:1.10.3300.10 6 177 1.4E-25 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_01370 1e5626d2a1993dbc923b461124e5a23e 178 Pfam PF07336 Putative stress-induced transcription regulator 8 129 7.8E-21 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator A4R43_01370 1e5626d2a1993dbc923b461124e5a23e 178 Pfam PF11706 CGNR zinc finger 133 175 1.7E-16 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_01370 1e5626d2a1993dbc923b461124e5a23e 178 SUPERFAMILY SSF160904 3 174 6.54E-40 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Pfam PF00009 Elongation factor Tu GTP binding domain 2 241 8.4E-54 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 SUPERFAMILY SSF52540 3 241 5.12E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Pfam PF00679 Elongation factor G C-terminus 532 613 1.7E-8 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR00315 GTP-binding elongation factor signature 71 81 3.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR00315 GTP-binding elongation factor signature 51 59 3.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR00315 GTP-binding elongation factor signature 123 132 3.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR00315 GTP-binding elongation factor signature 5 18 3.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR00315 GTP-binding elongation factor signature 87 98 3.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Gene3D G3DSA:3.30.70.870 343 416 6.3E-10 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Pfam PF14492 Elongation Factor G, domain II 343 414 9.9E-9 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 214 236 3.3E-22 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 269 295 3.3E-22 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 501 518 3.3E-22 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 3.3E-22 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Gene3D G3DSA:2.40.30.10 249 338 6.7E-7 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 SUPERFAMILY SSF54980 531 613 6.04E-10 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Gene3D G3DSA:3.30.230.10 442 611 1.0E-19 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Gene3D G3DSA:3.30.70.240 535 605 1.0E-19 T 14-10-2018 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 134 5.5E-29 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Pfam PF03764 Elongation factor G, domain IV 441 528 6.0E-9 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 SMART SM00889 420 529 5.9E-5 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 SUPERFAMILY SSF50447 224 333 1.14E-11 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 SUPERFAMILY SSF54211 439 529 5.69E-10 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 SUPERFAMILY SSF54980 343 418 3.31E-11 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_40400 66daa60ff65b98c750f7ff7442e047c7 616 Gene3D G3DSA:3.40.50.300 1 248 1.4E-67 T 14-10-2018 A4R43_18080 e1da96acb15f9012e2b8fd95f8290bdd 81 Gene3D G3DSA:1.10.1200.10 2 81 9.7E-25 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_18080 e1da96acb15f9012e2b8fd95f8290bdd 81 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 37 76 2.0E-12 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A4R43_18080 e1da96acb15f9012e2b8fd95f8290bdd 81 Hamap MF_01217 Acyl carrier protein [acpP]. 6 80 17.28 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A4R43_18080 e1da96acb15f9012e2b8fd95f8290bdd 81 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 5 79 1.3E-20 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A4R43_18080 e1da96acb15f9012e2b8fd95f8290bdd 81 Pfam PF00550 Phosphopantetheine attachment site 11 76 3.2E-16 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_18080 e1da96acb15f9012e2b8fd95f8290bdd 81 SUPERFAMILY SSF47336 2 79 1.09E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_25900 f58939176cd7a984a12134895f59458e 132 SUPERFAMILY SSF50331 10 127 1.9E-17 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_25900 f58939176cd7a984a12134895f59458e 132 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 39 1.3E-7 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A4R43_25900 f58939176cd7a984a12134895f59458e 132 Gene3D G3DSA:2.40.50.100 65 128 1.8E-17 T 14-10-2018 A4R43_25900 f58939176cd7a984a12134895f59458e 132 Gene3D G3DSA:1.10.1660.10 2 53 1.3E-8 T 14-10-2018 A4R43_25900 f58939176cd7a984a12134895f59458e 132 Pfam PF03459 TOBE domain 66 127 2.6E-11 T 14-10-2018 IPR005116 Transport-associated OB, type 1 A4R43_25900 f58939176cd7a984a12134895f59458e 132 Pfam PF12728 Helix-turn-helix domain 6 53 1.0E-9 T 14-10-2018 A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 SMART SM00895 108 230 3.6E-11 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 SUPERFAMILY SSF48008 104 238 8.63E-17 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 SUPERFAMILY SSF46785 12 93 2.48E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 SMART SM00345 22 83 3.1E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 Gene3D G3DSA:1.20.120.530 103 241 1.4E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 1.4E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 Gene3D G3DSA:1.10.10.10 17 86 1.4E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 2.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 2.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_37770 f9e5dae61db24e2bd405747c46e77114 243 Pfam PF07729 FCD domain 112 228 2.6E-15 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_11360 e3a0169efbe2a3c72d04bb8e0ee8f5bf 432 Pfam PF13347 MFS/sugar transport protein 9 423 1.6E-70 T 14-10-2018 A4R43_11360 e3a0169efbe2a3c72d04bb8e0ee8f5bf 432 SUPERFAMILY SSF103473 8 425 4.97E-27 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_11360 e3a0169efbe2a3c72d04bb8e0ee8f5bf 432 Gene3D G3DSA:1.20.1250.20 222 425 5.9E-8 T 14-10-2018 A4R43_11360 e3a0169efbe2a3c72d04bb8e0ee8f5bf 432 Gene3D G3DSA:1.20.1250.20 6 205 7.4E-11 T 14-10-2018 A4R43_15880 bdc80d6c2e851977677ef315c4ec9991 368 SUPERFAMILY SSF51412 1 362 9.77E-50 T 14-10-2018 A4R43_15880 bdc80d6c2e851977677ef315c4ec9991 368 Pfam PF03060 Nitronate monooxygenase 4 356 5.2E-48 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_15880 bdc80d6c2e851977677ef315c4ec9991 368 Gene3D G3DSA:3.20.20.70 1 366 1.5E-94 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_14545 f6d7a6a6f9b7c066dcd21df1bd8e8042 574 SUPERFAMILY SSF53383 12 358 4.14E-51 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_14545 f6d7a6a6f9b7c066dcd21df1bd8e8042 574 Pfam PF00266 Aminotransferase class-V 58 335 3.0E-27 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_14545 f6d7a6a6f9b7c066dcd21df1bd8e8042 574 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 404 488 1.0E-16 T 14-10-2018 IPR013559 YheO-like A4R43_14545 f6d7a6a6f9b7c066dcd21df1bd8e8042 574 Pfam PF08348 YheO-like PAS domain 387 492 2.6E-29 T 14-10-2018 IPR013559 YheO-like A4R43_14545 f6d7a6a6f9b7c066dcd21df1bd8e8042 574 Gene3D G3DSA:3.40.640.10 28 276 8.5E-57 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_14545 f6d7a6a6f9b7c066dcd21df1bd8e8042 574 Gene3D G3DSA:3.90.1150.10 18 350 8.5E-57 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_14545 f6d7a6a6f9b7c066dcd21df1bd8e8042 574 Pfam PF13309 HTH domain 512 570 2.3E-19 T 14-10-2018 IPR039445 Transcriptional regulator DauR-like, HTH domain A4R43_10065 e75b90b39d60a9ed01c7fc3ef21320f9 316 Gene3D G3DSA:1.10.10.60 208 311 4.5E-31 T 14-10-2018 A4R43_10065 e75b90b39d60a9ed01c7fc3ef21320f9 316 Pfam PF12833 Helix-turn-helix domain 230 308 7.1E-26 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_10065 e75b90b39d60a9ed01c7fc3ef21320f9 316 Gene3D G3DSA:3.40.50.880 1 201 1.8E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_10065 e75b90b39d60a9ed01c7fc3ef21320f9 316 Pfam PF01965 DJ-1/PfpI family 3 168 3.5E-18 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_10065 e75b90b39d60a9ed01c7fc3ef21320f9 316 SUPERFAMILY SSF46689 261 310 4.66E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_10065 e75b90b39d60a9ed01c7fc3ef21320f9 316 SUPERFAMILY SSF46689 210 258 3.51E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_10065 e75b90b39d60a9ed01c7fc3ef21320f9 316 SMART SM00342 224 307 1.8E-32 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_10065 e75b90b39d60a9ed01c7fc3ef21320f9 316 SUPERFAMILY SSF52317 1 187 7.83E-45 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_09765 f38d1d7e236894b5d3d556154d7e343c 136 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 3 119 1.7E-38 T 14-10-2018 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family KEGG: 00253+1.3.98.4|MetaCyc: PWY-7812 A4R43_09765 f38d1d7e236894b5d3d556154d7e343c 136 SUPERFAMILY SSF50475 3 118 6.36E-15 T 14-10-2018 A4R43_09765 f38d1d7e236894b5d3d556154d7e343c 136 Gene3D G3DSA:2.30.110.10 4 118 1.0E-14 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_09765 f38d1d7e236894b5d3d556154d7e343c 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 96 1.3E-9 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_10750 92ed788e2d80fc23a62a19d9cbc0c295 343 SUPERFAMILY SSF110296 40 311 1.02E-35 T 14-10-2018 A4R43_10750 92ed788e2d80fc23a62a19d9cbc0c295 343 Gene3D G3DSA:2.130.10.10 145 282 4.0E-8 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_10750 92ed788e2d80fc23a62a19d9cbc0c295 343 Gene3D G3DSA:2.130.10.10 29 144 1.7E-10 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 ProSitePatterns PS00216 Sugar transport proteins signature 1. 336 353 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 Pfam PF07690 Major Facilitator Superfamily 24 426 2.2E-50 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 SUPERFAMILY SSF103473 11 205 6.28E-46 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 SUPERFAMILY SSF103473 217 474 1.09E-25 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 Gene3D G3DSA:1.20.1250.20 275 474 3.4E-20 T 14-10-2018 A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 2.8E-5 T 14-10-2018 A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 2.8E-5 T 14-10-2018 A4R43_17925 1739d3ec0c9d1c812d53e76faf430500 491 Gene3D G3DSA:1.20.1720.10 20 231 9.8E-48 T 14-10-2018 A4R43_17690 9c4c85a19f39d6243c5fd2e45ac29a6c 382 SUPERFAMILY SSF50022 298 380 5.11E-24 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_17690 9c4c85a19f39d6243c5fd2e45ac29a6c 382 Pfam PF00355 Rieske [2Fe-2S] domain 290 354 6.1E-10 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4R43_17690 9c4c85a19f39d6243c5fd2e45ac29a6c 382 Gene3D G3DSA:2.102.10.10 220 378 9.0E-33 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_10015 daba82e5d9f79d0df17beba743d0e959 463 SUPERFAMILY SSF56176 2 214 4.49E-68 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_10015 daba82e5d9f79d0df17beba743d0e959 463 Pfam PF02913 FAD linked oxidases, C-terminal domain 224 455 2.1E-59 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_10015 daba82e5d9f79d0df17beba743d0e959 463 Gene3D G3DSA:3.30.70.2740 333 415 2.1E-12 T 14-10-2018 A4R43_10015 daba82e5d9f79d0df17beba743d0e959 463 Gene3D G3DSA:3.30.465.40 5 232 2.3E-70 T 14-10-2018 A4R43_10015 daba82e5d9f79d0df17beba743d0e959 463 Gene3D G3DSA:1.10.45.10 416 456 3.1E-16 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4R43_10015 daba82e5d9f79d0df17beba743d0e959 463 SUPERFAMILY SSF55103 221 458 1.11E-58 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_10015 daba82e5d9f79d0df17beba743d0e959 463 Pfam PF01565 FAD binding domain 40 179 1.2E-40 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_28560 2d0b28878952760520a1f832b69fa74a 153 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 96 9.8E-17 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_28560 2d0b28878952760520a1f832b69fa74a 153 Gene3D G3DSA:2.30.110.10 11 143 4.6E-38 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_28560 2d0b28878952760520a1f832b69fa74a 153 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 3.1E-40 T 14-10-2018 IPR019920 F420-binding domain, putative A4R43_28560 2d0b28878952760520a1f832b69fa74a 153 SUPERFAMILY SSF50475 16 140 7.69E-33 T 14-10-2018 A4R43_35965 a9031d626c35cca03733ac268b0eb20b 362 SUPERFAMILY SSF81324 37 169 6.28E-20 T 14-10-2018 A4R43_35965 a9031d626c35cca03733ac268b0eb20b 362 Pfam PF07885 Ion channel 55 130 8.7E-13 T 14-10-2018 IPR013099 Potassium channel domain A4R43_35965 a9031d626c35cca03733ac268b0eb20b 362 Gene3D G3DSA:3.40.50.720 143 284 2.2E-38 T 14-10-2018 A4R43_35965 a9031d626c35cca03733ac268b0eb20b 362 Gene3D G3DSA:1.10.287.70 39 142 1.4E-13 T 14-10-2018 A4R43_35965 a9031d626c35cca03733ac268b0eb20b 362 Pfam PF02254 TrkA-N domain 150 268 1.0E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4R43_35965 a9031d626c35cca03733ac268b0eb20b 362 SUPERFAMILY SSF51735 146 291 7.39E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_30180 07e33d8e5fed6ea229ec7ee645d68e63 414 Gene3D G3DSA:1.10.10.2840 278 403 1.2E-18 T 14-10-2018 A4R43_30180 07e33d8e5fed6ea229ec7ee645d68e63 414 Pfam PF13556 PucR C-terminal helix-turn-helix domain 345 401 2.7E-15 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_04705 f022d1949cca14741503c14577ee5a69 162 Gene3D G3DSA:1.10.10.1930 75 162 1.3E-33 T 14-10-2018 IPR038099 BldD-like, C-terminal domain superfamily A4R43_04705 f022d1949cca14741503c14577ee5a69 162 SMART SM00530 11 68 1.3E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_04705 f022d1949cca14741503c14577ee5a69 162 Gene3D G3DSA:1.10.260.40 1 70 1.6E-31 T 14-10-2018 A4R43_04705 f022d1949cca14741503c14577ee5a69 162 Pfam PF01381 Helix-turn-helix 13 68 1.8E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_04705 f022d1949cca14741503c14577ee5a69 162 SUPERFAMILY SSF47413 4 71 1.38E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_15745 c4dd68c44df4b04aff454e6423fb471e 277 Pfam PF04909 Amidohydrolase 5 248 8.5E-38 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_15745 c4dd68c44df4b04aff454e6423fb471e 277 Gene3D G3DSA:3.20.20.140 2 276 8.1E-74 T 14-10-2018 A4R43_15745 c4dd68c44df4b04aff454e6423fb471e 277 SUPERFAMILY SSF51556 2 273 3.77E-65 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_11535 35eda041aa628bf42dbf604acaf874ad 217 Pfam PF03070 TENA/THI-4/PQQC family 27 212 5.7E-8 T 14-10-2018 IPR004305 Thiaminase-2/PQQC A4R43_11535 35eda041aa628bf42dbf604acaf874ad 217 SUPERFAMILY SSF48613 4 212 7.97E-29 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_11535 35eda041aa628bf42dbf604acaf874ad 217 Gene3D G3DSA:1.20.910.10 1 215 2.8E-16 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 167 265 3.6E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 SUPERFAMILY SSF47203 277 436 2.58E-38 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 Gene3D G3DSA:1.20.140.10 490 602 1.2E-16 T 14-10-2018 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 Gene3D G3DSA:1.10.540.10 51 165 1.1E-127 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 SUPERFAMILY SSF56645 76 290 1.96E-57 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 58 163 6.8E-19 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 Gene3D G3DSA:2.40.110.10 166 276 1.1E-127 T 14-10-2018 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 277 435 1.0E-34 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_17905 e38c3b545e7200850c52d3a89eeb7024 647 Gene3D G3DSA:1.20.140.10 277 433 1.1E-127 T 14-10-2018 A4R43_21885 47313df799e0e9a23980c416dbf87c07 260 Gene3D G3DSA:3.30.450.40 82 260 7.7E-40 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_21885 47313df799e0e9a23980c416dbf87c07 260 SUPERFAMILY SSF55781 72 258 2.81E-39 T 14-10-2018 A4R43_21885 47313df799e0e9a23980c416dbf87c07 260 SUPERFAMILY SSF46785 7 80 3.05E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_21885 47313df799e0e9a23980c416dbf87c07 260 Pfam PF09339 IclR helix-turn-helix domain 9 58 3.3E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_21885 47313df799e0e9a23980c416dbf87c07 260 Gene3D G3DSA:1.10.10.10 3 78 2.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21885 47313df799e0e9a23980c416dbf87c07 260 SMART SM00346 7 97 7.4E-23 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_21885 47313df799e0e9a23980c416dbf87c07 260 Pfam PF01614 Bacterial transcriptional regulator 128 225 5.4E-19 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_28625 11a21fe9b155ae57752b40af2fc327fa 533 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 43 451 7.5E-59 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_28625 11a21fe9b155ae57752b40af2fc327fa 533 Gene3D G3DSA:1.20.1730.10 30 520 2.0E-59 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_28625 11a21fe9b155ae57752b40af2fc327fa 533 Pfam PF00474 Sodium:solute symporter family 43 452 1.9E-94 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_05230 d1d258df00b00e1f1c219082744e4319 385 SUPERFAMILY SSF56645 2 241 1.26E-60 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_05230 d1d258df00b00e1f1c219082744e4319 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 377 2.7E-31 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_05230 d1d258df00b00e1f1c219082744e4319 385 Gene3D G3DSA:1.10.540.10 1 118 1.7E-26 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_05230 d1d258df00b00e1f1c219082744e4319 385 SUPERFAMILY SSF47203 226 383 7.89E-40 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_05230 d1d258df00b00e1f1c219082744e4319 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 200 7.8E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_05230 d1d258df00b00e1f1c219082744e4319 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 116 9.1E-23 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_05230 d1d258df00b00e1f1c219082744e4319 385 Gene3D G3DSA:1.20.140.10 234 379 8.8E-35 T 14-10-2018 A4R43_05230 d1d258df00b00e1f1c219082744e4319 385 Gene3D G3DSA:2.40.110.10 120 233 1.3E-29 T 14-10-2018 A4R43_37580 55b16d881503dc575f027cdeb7f9f3d8 749 SUPERFAMILY SSF53706 7 606 9.42E-144 T 14-10-2018 A4R43_37580 55b16d881503dc575f027cdeb7f9f3d8 749 Gene3D G3DSA:3.40.50.740 49 509 9.2E-175 T 14-10-2018 A4R43_37580 55b16d881503dc575f027cdeb7f9f3d8 749 Pfam PF01568 Molydopterin dinucleotide binding domain 605 719 1.6E-22 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4R43_37580 55b16d881503dc575f027cdeb7f9f3d8 749 Gene3D G3DSA:3.40.228.10 141 576 9.2E-175 T 14-10-2018 A4R43_37580 55b16d881503dc575f027cdeb7f9f3d8 749 Gene3D G3DSA:3.90.55.10 45 543 9.2E-175 T 14-10-2018 A4R43_37580 55b16d881503dc575f027cdeb7f9f3d8 749 Gene3D G3DSA:2.40.40.20 584 740 3.7E-40 T 14-10-2018 A4R43_37580 55b16d881503dc575f027cdeb7f9f3d8 749 Pfam PF00384 Molybdopterin oxidoreductase 49 500 1.3E-62 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_37580 55b16d881503dc575f027cdeb7f9f3d8 749 SUPERFAMILY SSF50692 598 743 2.49E-34 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 7.6E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 SUPERFAMILY SSF46894 139 206 1.9E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 SMART SM00421 142 199 3.3E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 Pfam PF00072 Response regulator receiver domain 4 115 2.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 SUPERFAMILY SSF52172 2 133 3.13E-36 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 SMART SM00448 2 115 1.9E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 Gene3D G3DSA:3.40.50.12740 2 205 5.9E-72 T 14-10-2018 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 8.2E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 8.2E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25675 b9bac3844d1ebd5d0001e32d049161b4 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 8.2E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 217 2.7E-46 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 259 465 5.5E-37 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 259 497 4.1E-83 T 14-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 Gene3D G3DSA:3.40.1010.10 4 134 2.4E-33 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 4 234 4.4E-63 T 14-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 Gene3D G3DSA:3.30.950.10 136 237 1.4E-13 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 SUPERFAMILY SSF53790 1 236 1.83E-47 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 SUPERFAMILY SSF53790 256 488 3.53E-51 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 101 133 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 Gene3D G3DSA:3.30.950.10 368 497 3.3E-50 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4R43_41510 f584e6bdd9c0220adc1ed39178fa9ed3 497 Gene3D G3DSA:3.40.1010.10 253 367 8.9E-27 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4R43_29485 ca74cf24fc43d3c4608cf74f743f4253 279 Pfam PF13649 Methyltransferase domain 48 141 1.5E-11 T 14-10-2018 A4R43_29485 ca74cf24fc43d3c4608cf74f743f4253 279 SUPERFAMILY SSF53335 26 216 1.15E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_29485 ca74cf24fc43d3c4608cf74f743f4253 279 Gene3D G3DSA:3.40.50.150 30 271 6.4E-23 T 14-10-2018 A4R43_02375 49cc5c488e41da4ea688c2d4887fe95f 306 Pfam PF13276 HTH-like domain 50 102 1.7E-15 T 14-10-2018 IPR025948 HTH-like domain A4R43_02375 49cc5c488e41da4ea688c2d4887fe95f 306 Pfam PF00665 Integrase core domain 129 247 1.3E-23 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4R43_02375 49cc5c488e41da4ea688c2d4887fe95f 306 Gene3D G3DSA:3.30.420.10 120 228 9.6E-9 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_02375 49cc5c488e41da4ea688c2d4887fe95f 306 SUPERFAMILY SSF53098 123 296 1.67E-34 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_04395 d1101ef76d97c33c171a7f584f929127 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 444 1.1E-76 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_04395 d1101ef76d97c33c171a7f584f929127 527 SUPERFAMILY SSF53850 47 522 2.17E-106 T 14-10-2018 A4R43_04395 d1101ef76d97c33c171a7f584f929127 527 Gene3D G3DSA:3.40.190.10 19 277 1.9E-57 T 14-10-2018 A4R43_04395 d1101ef76d97c33c171a7f584f929127 527 Gene3D G3DSA:3.10.105.10 281 496 2.2E-41 T 14-10-2018 A4R43_04395 d1101ef76d97c33c171a7f584f929127 527 PIRSF PIRSF002741 7 525 1.4E-79 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_17405 04bddc8e74ad2a31ae5f753b7ac8eef2 232 SUPERFAMILY SSF81606 5 230 1.19E-61 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_17405 04bddc8e74ad2a31ae5f753b7ac8eef2 232 SMART SM00332 2 229 4.8E-22 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_17405 04bddc8e74ad2a31ae5f753b7ac8eef2 232 SMART SM00331 11 231 3.1E-34 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_17405 04bddc8e74ad2a31ae5f753b7ac8eef2 232 Pfam PF13672 Protein phosphatase 2C 20 207 1.8E-9 T 14-10-2018 A4R43_17405 04bddc8e74ad2a31ae5f753b7ac8eef2 232 Gene3D G3DSA:3.60.40.10 1 232 3.5E-62 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_26175 ea0d2b7a0f6ededc628695ebd5e32f1f 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 3.4E-19 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis A4R43_26175 ea0d2b7a0f6ededc628695ebd5e32f1f 66 Pfam PF02597 ThiS family 5 66 1.2E-13 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A4R43_26175 ea0d2b7a0f6ededc628695ebd5e32f1f 66 Gene3D G3DSA:3.10.20.30 1 66 1.6E-20 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_26175 ea0d2b7a0f6ededc628695ebd5e32f1f 66 SUPERFAMILY SSF54285 1 66 1.89E-16 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4R43_10045 a27bb6aadab34a6172aec95c8aed9627 154 SUPERFAMILY SSF54292 4 79 9.83E-22 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_10045 a27bb6aadab34a6172aec95c8aed9627 154 SUPERFAMILY SSF47741 74 150 3.4E-30 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_10045 a27bb6aadab34a6172aec95c8aed9627 154 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 55 1.3E-6 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_10045 a27bb6aadab34a6172aec95c8aed9627 154 Pfam PF01799 [2Fe-2S] binding domain 74 142 5.8E-26 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_10045 a27bb6aadab34a6172aec95c8aed9627 154 Gene3D G3DSA:3.10.20.30 3 76 3.4E-24 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_10045 a27bb6aadab34a6172aec95c8aed9627 154 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_10045 a27bb6aadab34a6172aec95c8aed9627 154 Gene3D G3DSA:1.10.150.120 77 153 5.8E-25 T 14-10-2018 A4R43_11875 f090c04e79c7a1cb51480579b41f6f9a 187 SUPERFAMILY SSF48498 96 183 4.6E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11875 f090c04e79c7a1cb51480579b41f6f9a 187 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_11875 f090c04e79c7a1cb51480579b41f6f9a 187 Gene3D G3DSA:1.10.357.10 9 186 5.6E-45 T 14-10-2018 A4R43_11875 f090c04e79c7a1cb51480579b41f6f9a 187 SUPERFAMILY SSF46689 5 73 2.31E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11875 f090c04e79c7a1cb51480579b41f6f9a 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11875 f090c04e79c7a1cb51480579b41f6f9a 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11875 f090c04e79c7a1cb51480579b41f6f9a 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 2.7E-20 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20120 d99ab457cd645ead52dba09032be6387 396 PIRSF PIRSF005572 1 384 1.7E-114 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A4R43_20120 d99ab457cd645ead52dba09032be6387 396 Pfam PF00266 Aminotransferase class-V 3 370 7.8E-65 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_20120 d99ab457cd645ead52dba09032be6387 396 Gene3D G3DSA:3.90.1150.10 3 369 3.6E-141 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_20120 d99ab457cd645ead52dba09032be6387 396 SUPERFAMILY SSF53383 1 378 3.32E-94 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_20120 d99ab457cd645ead52dba09032be6387 396 Gene3D G3DSA:3.40.640.10 13 260 3.6E-141 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_20085 0d1f93d32de99c2386aa6fbd258932dd 277 SUPERFAMILY SSF56317 1 265 1.7E-69 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_20085 0d1f93d32de99c2386aa6fbd258932dd 277 Pfam PF00795 Carbon-nitrogen hydrolase 2 249 6.0E-40 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_20085 0d1f93d32de99c2386aa6fbd258932dd 277 Gene3D G3DSA:3.60.110.10 1 263 1.2E-73 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 SUPERFAMILY SSF51419 50 308 1.83E-63 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 Gene3D G3DSA:3.20.20.10 58 306 7.8E-136 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 79 97 4.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 99 111 4.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 296 315 4.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 214 227 4.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 396 409 4.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 39 439 36.847 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 SUPERFAMILY SSF50621 284 439 5.23E-47 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 Gene3D G3DSA:2.40.37.10 38 435 7.8E-136 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 307 396 1.9E-17 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 79 97 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01181 Diaminopimelate decarboxylase signature 183 192 3.5E-23 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01181 Diaminopimelate decarboxylase signature 406 428 3.5E-23 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01181 Diaminopimelate decarboxylase signature 97 114 3.5E-23 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 PRINTS PR01181 Diaminopimelate decarboxylase signature 323 341 3.5E-23 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 59 306 3.4E-56 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4R43_32210 4f4ff10d098a8de0f2e043a9327ba3cd 440 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 31 438 5.6E-119 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_29770 ea3aebb58d2743e309cd69540e90d19a 367 Gene3D G3DSA:3.90.180.10 21 362 6.1E-87 T 14-10-2018 A4R43_29770 ea3aebb58d2743e309cd69540e90d19a 367 Gene3D G3DSA:3.40.50.720 170 314 6.1E-87 T 14-10-2018 A4R43_29770 ea3aebb58d2743e309cd69540e90d19a 367 SUPERFAMILY SSF50129 7 363 4.42E-39 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_29770 ea3aebb58d2743e309cd69540e90d19a 367 SMART SM00829 4 361 3.4E-5 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_29770 ea3aebb58d2743e309cd69540e90d19a 367 Pfam PF00107 Zinc-binding dehydrogenase 194 327 6.8E-27 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_29770 ea3aebb58d2743e309cd69540e90d19a 367 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 149 2.0E-23 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_29770 ea3aebb58d2743e309cd69540e90d19a 367 SUPERFAMILY SSF51735 157 329 2.48E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_29770 ea3aebb58d2743e309cd69540e90d19a 367 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_29475 49fabddcd62c6675bd3d6889af10f1bd 165 Gene3D G3DSA:3.90.79.10 3 159 1.3E-21 T 14-10-2018 A4R43_29475 49fabddcd62c6675bd3d6889af10f1bd 165 PRINTS PR00502 NUDIX hydrolase family signature 56 70 2.3E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_29475 49fabddcd62c6675bd3d6889af10f1bd 165 PRINTS PR00502 NUDIX hydrolase family signature 70 85 2.3E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_29475 49fabddcd62c6675bd3d6889af10f1bd 165 SUPERFAMILY SSF55811 32 156 2.03E-21 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_29475 49fabddcd62c6675bd3d6889af10f1bd 165 ProSitePatterns PS00893 Nudix box signature. 61 82 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_29475 49fabddcd62c6675bd3d6889af10f1bd 165 Pfam PF00293 NUDIX domain 31 140 4.0E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_25695 7f15d3f7ab293a3f39e0c154c831a11c 494 SUPERFAMILY SSF51338 36 457 4.52E-14 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25695 7f15d3f7ab293a3f39e0c154c831a11c 494 Gene3D G3DSA:2.30.40.10 41 89 1.5E-23 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25695 7f15d3f7ab293a3f39e0c154c831a11c 494 Pfam PF01979 Amidohydrolase family 357 458 1.1E-12 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_25695 7f15d3f7ab293a3f39e0c154c831a11c 494 Gene3D G3DSA:3.30.110.90 402 424 3.1E-27 T 14-10-2018 A4R43_25695 7f15d3f7ab293a3f39e0c154c831a11c 494 Gene3D G3DSA:1.20.58.520 308 401 3.1E-27 T 14-10-2018 A4R43_25695 7f15d3f7ab293a3f39e0c154c831a11c 494 Gene3D G3DSA:2.30.40.10 425 458 3.1E-27 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25695 7f15d3f7ab293a3f39e0c154c831a11c 494 SUPERFAMILY SSF51556 89 425 4.61E-43 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_25695 7f15d3f7ab293a3f39e0c154c831a11c 494 Gene3D G3DSA:3.20.20.140 90 232 1.5E-23 T 14-10-2018 A4R43_05255 6224f281128b88eaa12b208caedd109a 383 Gene3D G3DSA:3.30.70.270 215 382 3.8E-56 T 14-10-2018 A4R43_05255 6224f281128b88eaa12b208caedd109a 383 SUPERFAMILY SSF55073 227 381 3.06E-48 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_05255 6224f281128b88eaa12b208caedd109a 383 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 380 1.4E-50 T 14-10-2018 IPR000160 GGDEF domain A4R43_05255 6224f281128b88eaa12b208caedd109a 383 Pfam PF00990 Diguanylate cyclase, GGDEF domain 223 378 1.7E-42 T 14-10-2018 IPR000160 GGDEF domain A4R43_05255 6224f281128b88eaa12b208caedd109a 383 SMART SM00267 210 382 1.3E-55 T 14-10-2018 IPR000160 GGDEF domain A4R43_08385 fe77bff560ec287c9a3a1cde62b639fa 115 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 112 24.2 T 14-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 A4R43_08385 fe77bff560ec287c9a3a1cde62b639fa 115 Gene3D G3DSA:2.20.28.270 1 80 1.2E-37 T 14-10-2018 IPR038638 RbpA superfamily A4R43_08385 fe77bff560ec287c9a3a1cde62b639fa 115 Pfam PF13397 RNA polymerase-binding protein 4 107 3.0E-42 T 14-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 A4R43_35855 3510aab0cc6b3aede0643947faca33ce 301 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 8 282 9.5E-106 T 14-10-2018 IPR025859 P-aminobenzoate N-oxygenase AurF A4R43_35855 3510aab0cc6b3aede0643947faca33ce 301 SUPERFAMILY SSF47240 20 236 1.08E-8 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_38150 41dd8cc557105e188fcec6fc38760a98 290 SUPERFAMILY SSF56529 70 289 8.37E-76 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_38150 41dd8cc557105e188fcec6fc38760a98 290 Gene3D G3DSA:3.90.850.10 75 290 4.9E-81 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_38150 41dd8cc557105e188fcec6fc38760a98 290 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 80 287 1.9E-68 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_29815 df3a3dcf97e4015ac60e235eb8ffb693 118 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 111 4.8E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_29815 df3a3dcf97e4015ac60e235eb8ffb693 118 SUPERFAMILY SSF54593 10 115 2.82E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_29815 df3a3dcf97e4015ac60e235eb8ffb693 118 Gene3D G3DSA:3.10.180.10 3 117 1.7E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_27645 1720c98dc95be81b9b418f96b7a7ac44 154 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 6 149 46.18 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A4R43_27645 1720c98dc95be81b9b418f96b7a7ac44 154 Gene3D G3DSA:3.40.140.10 2 154 4.8E-51 T 14-10-2018 A4R43_27645 1720c98dc95be81b9b418f96b7a7ac44 154 Pfam PF14437 MafB19-like deaminase 8 146 1.7E-24 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A4R43_27645 1720c98dc95be81b9b418f96b7a7ac44 154 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 90 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4R43_27645 1720c98dc95be81b9b418f96b7a7ac44 154 SUPERFAMILY SSF53927 6 149 5.02E-47 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_33890 b86c265ef0e347983f58eb085b80e6a5 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 5.0E-54 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4R43_33890 b86c265ef0e347983f58eb085b80e6a5 122 SMART SM01374 1 122 5.3E-86 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4R43_33890 b86c265ef0e347983f58eb085b80e6a5 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33890 b86c265ef0e347983f58eb085b80e6a5 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.1E-56 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4R43_33890 b86c265ef0e347983f58eb085b80e6a5 122 SUPERFAMILY SSF50193 2 122 4.32E-50 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_33890 b86c265ef0e347983f58eb085b80e6a5 122 Gene3D G3DSA:2.40.150.20 1 122 1.1E-52 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_33890 b86c265ef0e347983f58eb085b80e6a5 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.248 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4R43_36325 500caebe12e65088e348353122811b17 136 SUPERFAMILY SSF102712 2 131 7.32E-26 T 14-10-2018 A4R43_36325 500caebe12e65088e348353122811b17 136 SMART SM00232 1 132 4.4E-29 T 14-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 A4R43_36325 500caebe12e65088e348353122811b17 136 Gene3D G3DSA:3.40.140.10 1 136 2.2E-35 T 14-10-2018 A4R43_36325 500caebe12e65088e348353122811b17 136 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 119 7.1E-26 T 14-10-2018 IPR028090 JAB domain, prokaryotic A4R43_10590 ca0f9094a4b62800e6ab53d3bf92fb43 214 Pfam PF03781 Sulfatase-modifying factor enzyme 1 2 211 1.8E-39 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A4R43_10590 ca0f9094a4b62800e6ab53d3bf92fb43 214 Gene3D G3DSA:3.90.1580.10 3 213 5.1E-71 T 14-10-2018 A4R43_10590 ca0f9094a4b62800e6ab53d3bf92fb43 214 SUPERFAMILY SSF56436 1 212 3.3E-53 T 14-10-2018 IPR016187 C-type lectin fold A4R43_34820 791682bf810465caf026446385338624 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.2E-5 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_34820 791682bf810465caf026446385338624 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.2E-5 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_34820 791682bf810465caf026446385338624 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.2E-5 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_34820 791682bf810465caf026446385338624 64 SUPERFAMILY SSF54862 2 62 1.26E-11 T 14-10-2018 A4R43_34820 791682bf810465caf026446385338624 64 Pfam PF13459 4Fe-4S single cluster domain 3 60 1.4E-9 T 14-10-2018 A4R43_34820 791682bf810465caf026446385338624 64 Gene3D G3DSA:3.30.70.20 1 64 1.8E-15 T 14-10-2018 A4R43_21235 16d140b2b4dac829b59d598c0943216a 207 Gene3D G3DSA:3.10.180.10 28 111 3.8E-13 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_21235 16d140b2b4dac829b59d598c0943216a 207 Gene3D G3DSA:3.10.180.10 115 188 9.3E-7 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_21235 16d140b2b4dac829b59d598c0943216a 207 SUPERFAMILY SSF54593 4 102 4.4E-12 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_09650 6b6cb2770175c9ee025bf96009f4b6bd 433 Gene3D G3DSA:3.40.640.10 50 300 3.4E-168 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_09650 6b6cb2770175c9ee025bf96009f4b6bd 433 Pfam PF00464 Serine hydroxymethyltransferase 21 398 1.1E-158 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_09650 6b6cb2770175c9ee025bf96009f4b6bd 433 Gene3D G3DSA:3.90.1150.10 23 402 3.4E-168 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_09650 6b6cb2770175c9ee025bf96009f4b6bd 433 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 20 429 49.423 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_09650 6b6cb2770175c9ee025bf96009f4b6bd 433 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 235 251 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_09650 6b6cb2770175c9ee025bf96009f4b6bd 433 SUPERFAMILY SSF53383 20 430 3.89E-165 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_09650 6b6cb2770175c9ee025bf96009f4b6bd 433 PIRSF PIRSF000412 14 431 1.5E-152 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 Gene3D G3DSA:1.10.357.10 48 195 4.2E-38 T 14-10-2018 A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 Gene3D G3DSA:1.10.10.60 1 47 2.2E-19 T 14-10-2018 A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 PRINTS PR00400 Tetracycline repressor protein signature 115 134 4.3E-8 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 PRINTS PR00400 Tetracycline repressor protein signature 59 78 4.3E-8 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 PRINTS PR00400 Tetracycline repressor protein signature 8 31 4.3E-8 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 SUPERFAMILY SSF46689 1 50 3.04E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 SUPERFAMILY SSF48498 57 194 3.78E-33 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 40 4.8E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_39735 7eccb5dc13d9ed6eaf388007835beb88 198 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 52 193 8.7E-23 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Pfam PF03527 RHS protein 1255 1285 1.9E-8 T 14-10-2018 IPR001826 RHS protein A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Gene3D G3DSA:3.90.930.1 516 674 1.3E-13 T 14-10-2018 A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Gene3D G3DSA:3.90.930.1 820 910 5.1E-7 T 14-10-2018 A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Gene3D G3DSA:3.90.930.1 675 819 2.6E-9 T 14-10-2018 A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Gene3D G3DSA:2.180.10.10 1081 1352 6.2E-36 T 14-10-2018 A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 SUPERFAMILY SSF69322 635 926 2.35E-5 T 14-10-2018 A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 SUPERFAMILY SSF140453 89 164 4.19E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Pfam PF05593 RHS Repeat 1156 1185 1.2E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Pfam PF05593 RHS Repeat 859 893 7.3E-5 T 14-10-2018 IPR031325 RHS repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Pfam PF05593 RHS Repeat 689 725 1.5E-7 T 14-10-2018 IPR031325 RHS repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Pfam PF05593 RHS Repeat 626 662 1.3E-9 T 14-10-2018 IPR031325 RHS repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Pfam PF05593 RHS Repeat 836 873 1.4E-10 T 14-10-2018 IPR031325 RHS repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 Pfam PF05593 RHS Repeat 668 704 2.9E-8 T 14-10-2018 IPR031325 RHS repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 SUPERFAMILY SSF50998 824 1222 6.2E-5 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 626 663 2.2E-7 T 14-10-2018 IPR006530 YD repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1156 1190 6.6E-8 T 14-10-2018 IPR006530 YD repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 584 622 3.7E-6 T 14-10-2018 IPR006530 YD repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 919 953 1.6E-6 T 14-10-2018 IPR006530 YD repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 732 772 1.6E-9 T 14-10-2018 IPR006530 YD repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 836 877 1.9E-9 T 14-10-2018 IPR006530 YD repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 668 708 1.7E-10 T 14-10-2018 IPR006530 YD repeat A4R43_34250 8e1bfe20aaf020b39aeab6006e03b265 1488 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1280 1352 1.1E-21 T 14-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 A4R43_13115 7d919749e4279ca3ceb7995af31073e4 180 Pfam PF01047 MarR family 63 121 2.9E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_13115 7d919749e4279ca3ceb7995af31073e4 180 SUPERFAMILY SSF46785 32 170 2.03E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13115 7d919749e4279ca3ceb7995af31073e4 180 Gene3D G3DSA:1.10.10.10 30 175 2.4E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13115 7d919749e4279ca3ceb7995af31073e4 180 SMART SM00347 56 155 2.1E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_13115 7d919749e4279ca3ceb7995af31073e4 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 132 8.5E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_13115 7d919749e4279ca3ceb7995af31073e4 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 8.5E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_13115 7d919749e4279ca3ceb7995af31073e4 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 146 166 8.5E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_13115 7d919749e4279ca3ceb7995af31073e4 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 112 8.5E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_19640 3f0919cce1bd872aa204d661296f3e0d 291 SUPERFAMILY SSF53474 2 287 3.39E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_19640 3f0919cce1bd872aa204d661296f3e0d 291 Pfam PF12697 Alpha/beta hydrolase family 26 282 1.4E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_19640 3f0919cce1bd872aa204d661296f3e0d 291 Gene3D G3DSA:3.40.50.1820 6 285 8.0E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_19640 3f0919cce1bd872aa204d661296f3e0d 291 PRINTS PR00412 Epoxide hydrolase signature 264 286 9.8E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_19640 3f0919cce1bd872aa204d661296f3e0d 291 PRINTS PR00412 Epoxide hydrolase signature 30 48 9.8E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_19640 3f0919cce1bd872aa204d661296f3e0d 291 PRINTS PR00412 Epoxide hydrolase signature 50 65 9.8E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_19640 3f0919cce1bd872aa204d661296f3e0d 291 PRINTS PR00412 Epoxide hydrolase signature 95 108 9.8E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 25 314 3.8E-15 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 Gene3D G3DSA:3.40.50.720 99 289 1.3E-101 T 14-10-2018 A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 SUPERFAMILY SSF51735 99 291 9.29E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 215 231 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 186 208 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 Gene3D G3DSA:3.40.50.720 1 310 1.3E-101 T 14-10-2018 A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 SUPERFAMILY SSF52283 1 125 1.74E-26 T 14-10-2018 A4R43_21440 bd36316f4afd0236c2eb27bdf8192afd 317 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 289 1.4E-52 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_13535 17edb87d5b79c216ab96248a040b1dac 227 SUPERFAMILY SSF48008 86 218 1.96E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_13535 17edb87d5b79c216ab96248a040b1dac 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 1.1E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_13535 17edb87d5b79c216ab96248a040b1dac 227 Gene3D G3DSA:1.10.10.10 4 79 9.5E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13535 17edb87d5b79c216ab96248a040b1dac 227 Gene3D G3DSA:1.20.120.530 83 225 1.6E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_13535 17edb87d5b79c216ab96248a040b1dac 227 SUPERFAMILY SSF46785 12 82 3.38E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13535 17edb87d5b79c216ab96248a040b1dac 227 Pfam PF07729 FCD domain 90 211 3.4E-22 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_13535 17edb87d5b79c216ab96248a040b1dac 227 SMART SM00345 20 78 4.3E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_13535 17edb87d5b79c216ab96248a040b1dac 227 SMART SM00895 88 214 4.9E-9 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 Gene3D G3DSA:3.40.50.1220 185 360 1.4E-51 T 14-10-2018 A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 171 1.3E-56 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 SUPERFAMILY SSF52518 365 552 4.24E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 328 1.8E-40 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 Gene3D G3DSA:3.40.50.970 2 170 1.2E-66 T 14-10-2018 A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 SUPERFAMILY SSF52518 1 179 3.07E-55 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 541 3.6E-34 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 SUPERFAMILY SSF52467 156 354 5.01E-50 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_05990 7c76c19783a404484d5f98dbccca1dd4 565 Gene3D G3DSA:3.40.50.970 361 565 1.0E-53 T 14-10-2018 A4R43_22625 e88ae70ca3d51d16ceb1ce14581680e0 154 SUPERFAMILY SSF46785 4 118 4.62E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22625 e88ae70ca3d51d16ceb1ce14581680e0 154 Gene3D G3DSA:1.10.10.10 1 141 2.9E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22625 e88ae70ca3d51d16ceb1ce14581680e0 154 SMART SM00347 23 124 0.007 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_11930 cad32060a49f74b2c8d61d4c21e6428a 131 SUPERFAMILY SSF55811 8 129 4.06E-29 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_11930 cad32060a49f74b2c8d61d4c21e6428a 131 Pfam PF00293 NUDIX domain 13 118 5.4E-21 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_11930 cad32060a49f74b2c8d61d4c21e6428a 131 PRINTS PR00502 NUDIX hydrolase family signature 34 48 4.4E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_11930 cad32060a49f74b2c8d61d4c21e6428a 131 PRINTS PR00502 NUDIX hydrolase family signature 48 63 4.4E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_11930 cad32060a49f74b2c8d61d4c21e6428a 131 Gene3D G3DSA:3.90.79.10 4 130 5.3E-31 T 14-10-2018 A4R43_11930 cad32060a49f74b2c8d61d4c21e6428a 131 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_13050 ef19574a847ebaf07a295e417d065234 143 Pfam PF13474 SnoaL-like domain 39 138 1.0E-8 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_13050 ef19574a847ebaf07a295e417d065234 143 Gene3D G3DSA:3.10.450.50 2 142 3.0E-14 T 14-10-2018 A4R43_13050 ef19574a847ebaf07a295e417d065234 143 SUPERFAMILY SSF54427 41 140 4.75E-15 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 173 0.006 T 14-10-2018 A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 6.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 6.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 6.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 6.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 6.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 SUPERFAMILY SSF51735 3 236 6.76E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 Gene3D G3DSA:3.40.50.720 1 237 4.4E-76 T 14-10-2018 A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 233 3.3E-59 T 14-10-2018 A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 2.6E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 2.6E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13495 fb3429662838689d0a85a8d8a59015a6 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 2.6E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 SMART SM00382 282 475 1.2 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 SMART SM00382 30 226 7.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 SUPERFAMILY SSF52540 10 229 2.38E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 Gene3D G3DSA:3.40.50.300 2 244 1.6E-55 T 14-10-2018 A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 Pfam PF00005 ABC transporter 274 428 1.2E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 SUPERFAMILY SSF52540 273 480 3.95E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 Pfam PF00005 ABC transporter 21 170 1.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_38170 a2735e1bd2d01c6472fc6c806bf2ef29 500 Gene3D G3DSA:3.40.50.300 253 485 4.4E-39 T 14-10-2018 A4R43_32985 9fe0fbf50f16b284002832c4ccc5a45e 430 SUPERFAMILY SSF52540 184 401 3.65E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_32985 9fe0fbf50f16b284002832c4ccc5a45e 430 Gene3D G3DSA:3.40.50.300 185 422 2.3E-34 T 14-10-2018 A4R43_32985 9fe0fbf50f16b284002832c4ccc5a45e 430 Pfam PF13614 AAA domain 185 329 5.3E-11 T 14-10-2018 IPR025669 AAA domain A4R43_38375 2d2b7cf24888b785e72de102829df752 262 Gene3D G3DSA:3.40.50.720 1 261 3.9E-72 T 14-10-2018 A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 3.0E-47 T 14-10-2018 A4R43_38375 2d2b7cf24888b785e72de102829df752 262 SUPERFAMILY SSF51735 1 257 4.71E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38375 2d2b7cf24888b785e72de102829df752 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_20375 8397b8fb6300ef1a1ead03ac23440578 205 Pfam PF05908 Poly-gamma-glutamate hydrolase 24 181 5.3E-40 T 14-10-2018 IPR008585 Poly-gamma-glutamate hydrolase A4R43_20375 8397b8fb6300ef1a1ead03ac23440578 205 Gene3D G3DSA:3.40.630.100 5 203 3.3E-55 T 14-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily A4R43_36335 274b56ac9da02f468ae7565d5b73a3a2 316 SUPERFAMILY SSF53686 4 296 3.27E-83 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_36335 274b56ac9da02f468ae7565d5b73a3a2 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 299 2.6E-107 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A4R43_36335 274b56ac9da02f468ae7565d5b73a3a2 316 Gene3D G3DSA:3.40.50.1100 8 295 1.3E-98 T 14-10-2018 A4R43_36335 274b56ac9da02f468ae7565d5b73a3a2 316 Gene3D G3DSA:3.40.50.1100 40 159 1.3E-98 T 14-10-2018 A4R43_36335 274b56ac9da02f468ae7565d5b73a3a2 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A4R43_36335 274b56ac9da02f468ae7565d5b73a3a2 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 2.4E-65 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_09965 7fe37343d469aee6e336741bdfc445dd 357 Pfam PF13458 Periplasmic binding protein 14 336 3.7E-57 T 14-10-2018 IPR028081 Leucine-binding protein domain A4R43_09965 7fe37343d469aee6e336741bdfc445dd 357 SUPERFAMILY SSF53822 14 353 5.05E-61 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_09965 7fe37343d469aee6e336741bdfc445dd 357 Gene3D G3DSA:3.40.50.2300 16 339 2.2E-70 T 14-10-2018 A4R43_09965 7fe37343d469aee6e336741bdfc445dd 357 Gene3D G3DSA:3.40.50.2300 127 353 2.2E-70 T 14-10-2018 A4R43_30655 a6928958ccf8ff5dc20a95d5701345bd 205 Pfam PF08044 Domain of unknown function (DUF1707) 7 59 7.9E-20 T 14-10-2018 IPR012551 Protein of unknown function DUF1707 A4R43_14765 ca348b71c5bc6ee98c98522151c89244 95 SUPERFAMILY SSF47336 12 90 1.44E-9 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_14765 ca348b71c5bc6ee98c98522151c89244 95 Pfam PF00550 Phosphopantetheine attachment site 12 70 2.3E-6 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_14765 ca348b71c5bc6ee98c98522151c89244 95 Gene3D G3DSA:1.10.1200.10 1 88 2.6E-11 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_22345 fe479d5841e004ad31f4e9f10aceea5d 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 104 3.0E-24 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22345 fe479d5841e004ad31f4e9f10aceea5d 121 Gene3D G3DSA:2.60.15.10 1 120 4.9E-29 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22345 fe479d5841e004ad31f4e9f10aceea5d 121 SUPERFAMILY SSF51344 4 86 2.35E-20 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22345 fe479d5841e004ad31f4e9f10aceea5d 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 17.951 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22345 fe479d5841e004ad31f4e9f10aceea5d 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 74 3.0E-24 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22345 fe479d5841e004ad31f4e9f10aceea5d 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 2.9E-24 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 Pfam PF00067 Cytochrome P450 196 377 6.4E-19 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 SUPERFAMILY SSF48264 12 406 4.85E-100 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 Gene3D G3DSA:1.10.630.10 3 407 6.4E-145 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 297 324 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 98 109 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 279 290 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 145 161 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 162 177 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 198 220 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 325 340 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 346 355 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_17610 9680970fcef7043222cef629efbbdd69 407 PRINTS PR00359 B-class P450 signature 355 366 1.5E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 SMART SM00065 32 179 8.6E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 SUPERFAMILY SSF55781 32 181 7.63E-20 T 14-10-2018 A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 SMART SM01012 181 236 1.2E-21 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 PIRSF PIRSF036625 1 242 1.2E-50 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 Gene3D G3DSA:3.30.450.40 14 183 2.3E-21 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 SUPERFAMILY SSF52172 161 234 1.99E-11 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 Pfam PF13185 GAF domain 32 169 1.3E-12 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 Gene3D G3DSA:1.10.10.10 184 241 2.5E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29355 ad8fc787612f9c5572b3536281eb2024 242 Pfam PF03861 ANTAR domain 183 235 2.2E-20 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_14775 5363562188adb994ab3b1c85e22145ae 376 SUPERFAMILY SSF53756 3 370 1.18E-61 T 14-10-2018 A4R43_14775 5363562188adb994ab3b1c85e22145ae 376 Gene3D G3DSA:3.40.50.2000 9 367 3.8E-84 T 14-10-2018 A4R43_14775 5363562188adb994ab3b1c85e22145ae 376 Gene3D G3DSA:3.40.50.2000 199 355 3.8E-84 T 14-10-2018 A4R43_14775 5363562188adb994ab3b1c85e22145ae 376 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 259 338 3.3E-13 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_01030 862ac88e2bf7eefba12ac69a6034eca7 332 Pfam PF09588 YqaJ-like viral recombinase domain 20 158 2.4E-21 T 14-10-2018 IPR019080 YqaJ viral recombinase A4R43_01030 862ac88e2bf7eefba12ac69a6034eca7 332 Gene3D G3DSA:3.90.320.10 16 211 1.3E-31 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A4R43_01030 862ac88e2bf7eefba12ac69a6034eca7 332 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 18 167 1.3E-22 T 14-10-2018 IPR017482 Putative phage-type endonuclease A4R43_01030 862ac88e2bf7eefba12ac69a6034eca7 332 SUPERFAMILY SSF52980 19 203 1.39E-28 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4R43_41520 0883778ce0d66377f472bdc3aa75ec10 240 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 1 220 1.1E-45 T 14-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 A4R43_41520 0883778ce0d66377f472bdc3aa75ec10 240 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 1 236 7.2E-71 T 14-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 10 278 9.4E-53 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 Pfam PF00288 GHMP kinases N terminal domain 96 154 3.1E-9 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 Gene3D G3DSA:3.30.70.890 170 310 1.9E-45 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 Pfam PF08544 GHMP kinases C terminal 213 285 9.4E-9 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 9 298 31.391 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 SUPERFAMILY SSF55060 174 293 3.12E-23 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 PIRSF PIRSF010376 8 305 9.8E-80 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 SUPERFAMILY SSF54211 8 167 1.21E-42 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_24065 63b5835b97c6b454e44b6782682642e8 322 Gene3D G3DSA:3.30.230.10 3 169 2.3E-61 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_10235 4053ebf9cc365a7dc364d6ec4f86c928 228 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 187 5.2E-44 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_10235 4053ebf9cc365a7dc364d6ec4f86c928 228 SMART SM01007 10 188 1.1E-52 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_10235 4053ebf9cc365a7dc364d6ec4f86c928 228 Gene3D G3DSA:3.40.225.10 6 209 3.3E-57 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_10235 4053ebf9cc365a7dc364d6ec4f86c928 228 SUPERFAMILY SSF53639 3 211 2.16E-51 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_11020 2fb300d01f06cf14421c11272c2bfda8 192 Gene3D G3DSA:1.10.357.10 71 192 2.6E-25 T 14-10-2018 A4R43_11020 2fb300d01f06cf14421c11272c2bfda8 192 SUPERFAMILY SSF46689 2 75 1.25E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11020 2fb300d01f06cf14421c11272c2bfda8 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.2E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11020 2fb300d01f06cf14421c11272c2bfda8 192 Gene3D G3DSA:1.10.10.60 1 66 3.4E-25 T 14-10-2018 A4R43_11020 2fb300d01f06cf14421c11272c2bfda8 192 SUPERFAMILY SSF48498 79 192 1.34E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_09085 a27631bb24848118647a2e4c80dc3a61 469 Gene3D G3DSA:3.40.50.720 73 438 3.4E-152 T 14-10-2018 A4R43_09085 a27631bb24848118647a2e4c80dc3a61 469 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 73 196 3.3E-15 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_09085 a27631bb24848118647a2e4c80dc3a61 469 SUPERFAMILY SSF51735 61 231 2.63E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09085 a27631bb24848118647a2e4c80dc3a61 469 Gene3D G3DSA:3.30.360.10 200 458 3.4E-152 T 14-10-2018 A4R43_09555 4fd87dc7c1d85ca824be854d12b648a9 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_09555 4fd87dc7c1d85ca824be854d12b648a9 477 Gene3D G3DSA:3.40.605.10 26 466 1.6E-165 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_09555 4fd87dc7c1d85ca824be854d12b648a9 477 SUPERFAMILY SSF53720 4 473 2.88E-157 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_09555 4fd87dc7c1d85ca824be854d12b648a9 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_09555 4fd87dc7c1d85ca824be854d12b648a9 477 Gene3D G3DSA:3.40.309.10 253 441 1.6E-165 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_09555 4fd87dc7c1d85ca824be854d12b648a9 477 Pfam PF00171 Aldehyde dehydrogenase family 20 472 8.7E-158 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_05520 087596a749d22a57b548b8781e16114e 880 SUPERFAMILY SSF51445 280 443 8.85E-16 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_05520 087596a749d22a57b548b8781e16114e 880 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 43 275 5.3E-39 T 14-10-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain A4R43_05520 087596a749d22a57b548b8781e16114e 880 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 635 705 4.9E-8 T 14-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain A4R43_05520 087596a749d22a57b548b8781e16114e 880 Pfam PF10566 Glycoside hydrolase 97 280 509 1.4E-62 T 14-10-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain A4R43_05520 087596a749d22a57b548b8781e16114e 880 Gene3D G3DSA:2.60.120.1060 733 877 1.9E-42 T 14-10-2018 IPR038637 NPCBM domain superfamily A4R43_05520 087596a749d22a57b548b8781e16114e 880 Gene3D G3DSA:2.70.98.10 30 273 2.5E-26 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_05520 087596a749d22a57b548b8781e16114e 880 Pfam PF08305 NPCBM/NEW2 domain 739 877 4.4E-45 T 14-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module A4R43_05520 087596a749d22a57b548b8781e16114e 880 SMART SM00776 733 878 7.1E-59 T 14-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module A4R43_05520 087596a749d22a57b548b8781e16114e 880 Gene3D G3DSA:3.20.20.70 275 511 6.0E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_05520 087596a749d22a57b548b8781e16114e 880 Gene3D G3DSA:2.60.40.1180 512 602 9.1E-20 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta A4R43_05520 087596a749d22a57b548b8781e16114e 880 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 511 600 6.9E-20 T 14-10-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain A4R43_05520 087596a749d22a57b548b8781e16114e 880 SUPERFAMILY SSF49785 737 877 1.62E-40 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_18310 ac1b86e48e6ee5be881a199d35f44aed 284 Pfam PF13312 Domain of unknown function (DUF4081) 48 156 9.5E-40 T 14-10-2018 IPR025289 Domain of unknown function DUF4081 A4R43_18310 ac1b86e48e6ee5be881a199d35f44aed 284 Gene3D G3DSA:3.40.630.30 71 282 7.4E-20 T 14-10-2018 A4R43_18310 ac1b86e48e6ee5be881a199d35f44aed 284 SUPERFAMILY SSF55729 77 279 1.42E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_18310 ac1b86e48e6ee5be881a199d35f44aed 284 PIRSF PIRSF021603 2 284 4.2E-117 T 14-10-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like A4R43_18310 ac1b86e48e6ee5be881a199d35f44aed 284 Pfam PF08445 FR47-like protein 212 276 1.5E-10 T 14-10-2018 IPR013653 FR47-like GO:0016747 A4R43_37985 321844ab833137b7dc50638d35ab46bb 390 SUPERFAMILY SSF53383 22 389 1.36E-35 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_37985 321844ab833137b7dc50638d35ab46bb 390 Gene3D G3DSA:3.90.1150.10 286 390 2.3E-5 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_37985 321844ab833137b7dc50638d35ab46bb 390 Gene3D G3DSA:3.40.640.10 30 285 1.6E-30 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_29570 9a9477bae2e3cec2937c9727589121a6 284 Gene3D G3DSA:1.10.150.20 183 254 3.5E-55 T 14-10-2018 A4R43_29570 9a9477bae2e3cec2937c9727589121a6 284 SMART SM00279 182 217 3.5E-9 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A4R43_29570 9a9477bae2e3cec2937c9727589121a6 284 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 180 261 1.8E-16 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 A4R43_29570 9a9477bae2e3cec2937c9727589121a6 284 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 178 2.5E-32 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A4R43_29570 9a9477bae2e3cec2937c9727589121a6 284 Gene3D G3DSA:3.40.50.1010 6 263 3.5E-55 T 14-10-2018 A4R43_29570 9a9477bae2e3cec2937c9727589121a6 284 SMART SM00475 4 267 9.1E-42 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A4R43_29570 9a9477bae2e3cec2937c9727589121a6 284 SUPERFAMILY SSF88723 5 163 2.16E-27 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_29570 9a9477bae2e3cec2937c9727589121a6 284 SUPERFAMILY SSF47807 180 276 9.27E-16 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A4R43_40525 6e3468f353984bae77deb67f22621817 299 Gene3D G3DSA:1.10.3720.10 51 294 5.3E-73 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_40525 6e3468f353984bae77deb67f22621817 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 286 1.4E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_40525 6e3468f353984bae77deb67f22621817 299 SUPERFAMILY SSF161098 55 283 1.7E-64 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_31340 1afa02f4b9d38c68537ec7268398ec9e 720 Pfam PF13449 Esterase-like activity of phytase 449 704 1.2E-43 T 14-10-2018 IPR027372 Phytase-like domain A4R43_31340 1afa02f4b9d38c68537ec7268398ec9e 720 SUPERFAMILY SSF51004 49 407 1.49E-19 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily A4R43_31340 1afa02f4b9d38c68537ec7268398ec9e 720 Gene3D G3DSA:2.130.10.10 47 187 3.3E-9 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_04625 29263cc150aed720541346bd5cb3d60b 151 Gene3D G3DSA:2.70.70.10 1 149 7.4E-46 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_04625 29263cc150aed720541346bd5cb3d60b 151 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 67 79 - T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A4R43_04625 29263cc150aed720541346bd5cb3d60b 151 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 4 125 1.4E-43 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A4R43_04625 29263cc150aed720541346bd5cb3d60b 151 SUPERFAMILY SSF51261 3 146 2.79E-40 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_04625 29263cc150aed720541346bd5cb3d60b 151 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 5 123 1.1E-33 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A4R43_17550 69df61e2da793ae0579aca5b1aec830e 292 SUPERFAMILY SSF54675 19 122 1.37E-23 T 14-10-2018 A4R43_17550 69df61e2da793ae0579aca5b1aec830e 292 SUPERFAMILY SSF51690 123 291 5.1E-58 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4R43_17550 69df61e2da793ae0579aca5b1aec830e 292 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 23 290 7.0E-87 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A4R43_17550 69df61e2da793ae0579aca5b1aec830e 292 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 123 290 2.5E-57 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A4R43_17550 69df61e2da793ae0579aca5b1aec830e 292 PIRSF PIRSF006250 15 292 6.9E-93 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A4R43_17550 69df61e2da793ae0579aca5b1aec830e 292 Gene3D G3DSA:3.90.1170.20 27 289 2.3E-95 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A4R43_17550 69df61e2da793ae0579aca5b1aec830e 292 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 35 121 2.4E-16 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A4R43_17550 69df61e2da793ae0579aca5b1aec830e 292 Gene3D G3DSA:3.20.20.70 127 282 2.3E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_01875 1273c9c42b239681150ce81983216411 196 Pfam PF00857 Isochorismatase family 23 192 8.5E-25 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4R43_01875 1273c9c42b239681150ce81983216411 196 SUPERFAMILY SSF52499 5 193 9.16E-38 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_01875 1273c9c42b239681150ce81983216411 196 Gene3D G3DSA:3.40.50.850 2 193 1.2E-38 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 368 1.9E-175 T 14-10-2018 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 SUPERFAMILY SSF51735 158 329 2.01E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 SUPERFAMILY SSF50129 319 368 3.2E-9 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 Gene3D G3DSA:3.90.180.10 7 364 6.9E-117 T 14-10-2018 A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 SMART SM00829 10 362 7.1E-5 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 Pfam PF00107 Zinc-binding dehydrogenase 195 325 2.4E-18 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 153 1.1E-26 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 Gene3D G3DSA:3.40.50.720 172 311 6.9E-117 T 14-10-2018 A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_30085 be93e00ce83aa73f731ba7524d659351 368 SUPERFAMILY SSF50129 1 188 1.45E-61 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_36435 b7e3f5c3f65cb892558063cfa0dfd44c 268 SMART SM00530 5 60 1.9E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_36435 b7e3f5c3f65cb892558063cfa0dfd44c 268 SUPERFAMILY SSF47413 1 57 5.63E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_36435 b7e3f5c3f65cb892558063cfa0dfd44c 268 Pfam PF13560 Helix-turn-helix domain 2 63 1.5E-13 T 14-10-2018 A4R43_36435 b7e3f5c3f65cb892558063cfa0dfd44c 268 Gene3D G3DSA:1.10.260.40 1 64 6.2E-15 T 14-10-2018 A4R43_13020 0610a2d04475c5c4098eb7dad6d60df9 540 Gene3D G3DSA:3.30.300.310 439 538 1.9E-25 T 14-10-2018 A4R43_13020 0610a2d04475c5c4098eb7dad6d60df9 540 Pfam PF00501 AMP-binding enzyme 51 441 6.3E-91 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_13020 0610a2d04475c5c4098eb7dad6d60df9 540 Gene3D G3DSA:3.40.50.12780 41 438 3.8E-103 T 14-10-2018 A4R43_13020 0610a2d04475c5c4098eb7dad6d60df9 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_13020 0610a2d04475c5c4098eb7dad6d60df9 540 SUPERFAMILY SSF56801 44 537 5.23E-135 T 14-10-2018 A4R43_13020 0610a2d04475c5c4098eb7dad6d60df9 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 525 4.6E-14 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_26580 4a12840aa26e4eeb92ab8dcc775e2160 123 Gene3D G3DSA:3.90.550.10 1 116 3.0E-20 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_26580 4a12840aa26e4eeb92ab8dcc775e2160 123 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 116 2.8E-20 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4R43_26580 4a12840aa26e4eeb92ab8dcc775e2160 123 SUPERFAMILY SSF53448 1 115 6.1E-10 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 Pfam PF01037 Lrp/AsnC ligand binding domain 69 136 8.6E-16 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 5.5E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 SMART SM00344 1 106 4.9E-31 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 SUPERFAMILY SSF46785 1 61 1.03E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.6E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.6E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.6E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 Gene3D G3DSA:3.30.70.920 55 143 3.9E-16 T 14-10-2018 A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 SUPERFAMILY SSF54909 61 141 5.63E-15 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_20105 fe179e77766ee3bc09799f10fd71ec01 149 Gene3D G3DSA:1.10.10.10 1 54 4.7E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06380 a25bd79b59e07ab9c66479e504e48e9e 336 PRINTS PR00134 Glycosyl hydrolase family 10 signature 145 156 2.2E-17 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_06380 a25bd79b59e07ab9c66479e504e48e9e 336 PRINTS PR00134 Glycosyl hydrolase family 10 signature 103 115 2.2E-17 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_06380 a25bd79b59e07ab9c66479e504e48e9e 336 PRINTS PR00134 Glycosyl hydrolase family 10 signature 189 200 2.2E-17 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_06380 a25bd79b59e07ab9c66479e504e48e9e 336 PRINTS PR00134 Glycosyl hydrolase family 10 signature 218 230 2.2E-17 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_06380 a25bd79b59e07ab9c66479e504e48e9e 336 Gene3D G3DSA:3.20.20.80 29 336 1.6E-118 T 14-10-2018 A4R43_06380 a25bd79b59e07ab9c66479e504e48e9e 336 Pfam PF00331 Glycosyl hydrolase family 10 39 334 5.0E-109 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_06380 a25bd79b59e07ab9c66479e504e48e9e 336 SUPERFAMILY SSF51445 38 334 4.58E-114 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_06380 a25bd79b59e07ab9c66479e504e48e9e 336 SMART SM00633 72 334 1.4E-113 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_02955 5bd85170438144d2b0b5c8bb07be065f 134 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 126 1.4E-22 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A4R43_02955 5bd85170438144d2b0b5c8bb07be065f 134 Gene3D G3DSA:3.40.50.2300 2 132 6.7E-49 T 14-10-2018 A4R43_02955 5bd85170438144d2b0b5c8bb07be065f 134 SUPERFAMILY SSF52788 2 126 3.27E-35 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily A4R43_02955 5bd85170438144d2b0b5c8bb07be065f 134 SMART SM00226 3 128 8.5E-40 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A4R43_31525 2a43e4bfa90dc4517c7c1e5c19055789 288 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 22 142 1.5E-16 T 14-10-2018 A4R43_31525 2a43e4bfa90dc4517c7c1e5c19055789 288 Gene3D G3DSA:3.40.50.150 9 165 4.3E-28 T 14-10-2018 A4R43_31525 2a43e4bfa90dc4517c7c1e5c19055789 288 SUPERFAMILY SSF53335 26 143 4.18E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_11480 ac8547eb7eac7e125c2605ae391323fa 293 SUPERFAMILY SSF161098 22 293 5.14E-68 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_11480 ac8547eb7eac7e125c2605ae391323fa 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 286 2.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_11480 ac8547eb7eac7e125c2605ae391323fa 293 Gene3D G3DSA:1.10.3720.10 16 284 1.3E-59 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_40990 ca740572ba1f23f13d54bbf7b62eae30 409 Gene3D G3DSA:3.30.565.10 263 393 5.8E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_40990 ca740572ba1f23f13d54bbf7b62eae30 409 SUPERFAMILY SSF55874 270 392 8.09E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_40990 ca740572ba1f23f13d54bbf7b62eae30 409 Pfam PF07730 Histidine kinase 184 247 2.5E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_19925 429798472a78b6e52d517af55fb3d784 259 Gene3D G3DSA:3.40.50.1000 29 224 3.9E-44 T 14-10-2018 IPR023214 HAD superfamily A4R43_19925 429798472a78b6e52d517af55fb3d784 259 Gene3D G3DSA:1.10.150.240 40 120 3.9E-44 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_19925 429798472a78b6e52d517af55fb3d784 259 SUPERFAMILY SSF56784 28 246 2.38E-42 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_19925 429798472a78b6e52d517af55fb3d784 259 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 133 214 3.1E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19925 429798472a78b6e52d517af55fb3d784 259 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 219 3.9E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19925 429798472a78b6e52d517af55fb3d784 259 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 179 3.9E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19925 429798472a78b6e52d517af55fb3d784 259 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 145 3.9E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19925 429798472a78b6e52d517af55fb3d784 259 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 209 222 3.9E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19925 429798472a78b6e52d517af55fb3d784 259 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 27 38 3.9E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19925 429798472a78b6e52d517af55fb3d784 259 Pfam PF13419 Haloacid dehalogenase-like hydrolase 32 219 8.7E-22 T 14-10-2018 A4R43_02185 a601ae01c79f509ebddf7003f6db852c 599 Gene3D G3DSA:3.50.50.60 5 434 1.5E-118 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02185 a601ae01c79f509ebddf7003f6db852c 599 Gene3D G3DSA:2.30.110.10 439 519 1.5E-5 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_02185 a601ae01c79f509ebddf7003f6db852c 599 SUPERFAMILY SSF51905 7 243 5.08E-18 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02185 a601ae01c79f509ebddf7003f6db852c 599 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 10 355 4.9E-91 T 14-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A4R43_02185 a601ae01c79f509ebddf7003f6db852c 599 Pfam PF04299 Putative FMN-binding domain 452 515 1.7E-5 T 14-10-2018 IPR007396 Transcriptional regulator PAI 2-type A4R43_02185 a601ae01c79f509ebddf7003f6db852c 599 SUPERFAMILY SSF50475 453 588 2.22E-8 T 14-10-2018 A4R43_39530 800f04cf16a3558749df15edbcf1ef95 378 SMART SM00387 285 376 6.3E-4 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_39530 800f04cf16a3558749df15edbcf1ef95 378 Pfam PF07730 Histidine kinase 172 240 8.5E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_39530 800f04cf16a3558749df15edbcf1ef95 378 Gene3D G3DSA:3.30.565.10 255 375 8.8E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39530 800f04cf16a3558749df15edbcf1ef95 378 SUPERFAMILY SSF55874 261 373 8.03E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39530 800f04cf16a3558749df15edbcf1ef95 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 333 1.1E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_33145 1db7dc0440536f9804e220c591774a94 522 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 18 512 17.546 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A4R43_33145 1db7dc0440536f9804e220c591774a94 522 Pfam PF00361 Proton-conducting membrane transporter 164 457 1.6E-75 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33145 1db7dc0440536f9804e220c591774a94 522 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 144 511 5.9E-112 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A4R43_32560 dc5846b9e57c8aa60e8d2a4a2f7af6e8 262 Gene3D G3DSA:2.60.40.10 139 255 1.8E-25 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_32560 dc5846b9e57c8aa60e8d2a4a2f7af6e8 262 Gene3D G3DSA:2.60.40.10 22 138 1.7E-30 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_32560 dc5846b9e57c8aa60e8d2a4a2f7af6e8 262 SUPERFAMILY SSF117074 125 226 3.4E-15 T 14-10-2018 A4R43_32560 dc5846b9e57c8aa60e8d2a4a2f7af6e8 262 Pfam PF17210 SdrD B-like domain 24 135 1.1E-25 T 14-10-2018 IPR033764 SD-repeat containing protein, B domain A4R43_32560 dc5846b9e57c8aa60e8d2a4a2f7af6e8 262 Pfam PF17210 SdrD B-like domain 141 251 1.5E-24 T 14-10-2018 IPR033764 SD-repeat containing protein, B domain A4R43_32560 dc5846b9e57c8aa60e8d2a4a2f7af6e8 262 SUPERFAMILY SSF117074 20 96 4.32E-21 T 14-10-2018 A4R43_37395 c2ef70ebf672da0f63f4773242cfdcbc 130 Gene3D G3DSA:3.10.450.50 7 129 6.3E-39 T 14-10-2018 A4R43_37395 c2ef70ebf672da0f63f4773242cfdcbc 130 SUPERFAMILY SSF54427 28 126 4.75E-34 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_37395 c2ef70ebf672da0f63f4773242cfdcbc 130 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 4 127 27.843 T 14-10-2018 IPR023006 Uncharacterised protein family UPF0225 A4R43_11770 81a6f3c4764dad085fe0be27ae5ee793 191 SUPERFAMILY SSF46689 9 79 1.44E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11770 81a6f3c4764dad085fe0be27ae5ee793 191 Gene3D G3DSA:1.10.357.10 4 186 1.1E-50 T 14-10-2018 A4R43_11770 81a6f3c4764dad085fe0be27ae5ee793 191 SUPERFAMILY SSF48498 78 162 2.61E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11770 81a6f3c4764dad085fe0be27ae5ee793 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 4.6E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11770 81a6f3c4764dad085fe0be27ae5ee793 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11770 81a6f3c4764dad085fe0be27ae5ee793 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 Gene3D G3DSA:2.40.30.10 2 100 8.4E-22 T 14-10-2018 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 SUPERFAMILY SSF54292 215 333 6.95E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 SUPERFAMILY SSF52343 90 223 3.01E-30 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 256 328 6.8E-15 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 Pfam PF00970 Oxidoreductase FAD-binding domain 26 99 1.4E-4 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 SUPERFAMILY SSF63380 3 101 1.78E-21 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 Gene3D G3DSA:3.40.50.80 103 228 1.5E-27 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 109 128 4.7E-9 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 193 201 4.7E-9 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 52 59 4.7E-9 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 32 42 4.7E-9 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 133 142 4.7E-9 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 Gene3D G3DSA:3.10.20.30 231 338 3.9E-27 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 32 44 2.6E-9 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 193 201 2.6E-9 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 109 128 2.6E-9 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 Pfam PF00175 Oxidoreductase NAD-binding domain 111 207 5.5E-13 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_16070 8811eae4c6e7aea731e70d5a9ad33940 338 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 286 294 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_06295 69ab23081cf98e7012e98bccc264a562 192 Gene3D G3DSA:3.40.50.880 3 185 6.7E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_06295 69ab23081cf98e7012e98bccc264a562 192 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 176 4.1E-46 T 14-10-2018 IPR006286 Deglycase PfpI A4R43_06295 69ab23081cf98e7012e98bccc264a562 192 Pfam PF01965 DJ-1/PfpI family 9 177 7.7E-52 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_06295 69ab23081cf98e7012e98bccc264a562 192 SUPERFAMILY SSF52317 9 178 1.43E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 SUPERFAMILY SSF53067 8 160 3.24E-20 T 14-10-2018 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 SUPERFAMILY SSF50998 469 647 2.16E-5 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 PRINTS PR00301 70kDa heat shock protein signature 314 330 6.5E-7 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 PRINTS PR00301 70kDa heat shock protein signature 7 20 6.5E-7 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 PRINTS PR00301 70kDa heat shock protein signature 182 192 6.5E-7 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 SUPERFAMILY SSF53067 171 358 2.46E-32 T 14-10-2018 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 Pfam PF00012 Hsp70 protein 96 356 2.4E-26 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 Gene3D G3DSA:3.30.420.40 170 345 2.4E-87 T 14-10-2018 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 Gene3D G3DSA:2.130.10.10 442 741 1.2E-6 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 Gene3D G3DSA:3.90.640.10 208 295 2.4E-87 T 14-10-2018 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 317 331 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_21395 177d4d1a78fd1efcc1b793e566b34e95 843 Gene3D G3DSA:3.30.420.40 10 355 2.4E-87 T 14-10-2018 A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 PRINTS PR00095 Anthranilate synthase component I signature 358 371 4.2E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 PRINTS PR00095 Anthranilate synthase component I signature 453 467 4.2E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 PRINTS PR00095 Anthranilate synthase component I signature 438 452 4.2E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 PRINTS PR00095 Anthranilate synthase component I signature 344 357 4.2E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 SUPERFAMILY SSF56322 35 504 7.33E-156 T 14-10-2018 IPR005801 ADC synthase GO:0009058 A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 46 504 8.6E-171 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 Pfam PF00425 chorismate binding enzyme 243 496 5.4E-98 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 Pfam PF04715 Anthranilate synthase component I, N terminal region 47 187 7.9E-32 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_17245 3f8dfd23ffe46dcebdc825c3a28f25a5 525 Gene3D G3DSA:3.60.120.10 15 515 2.7E-202 T 14-10-2018 IPR005801 ADC synthase GO:0009058 A4R43_20100 f8d9de411e9419b594066ccc9e2d9b69 306 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 33 281 1.1E-60 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region A4R43_20100 f8d9de411e9419b594066ccc9e2d9b69 306 Gene3D G3DSA:2.120.10.30 3 291 7.2E-103 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_20100 f8d9de411e9419b594066ccc9e2d9b69 306 SUPERFAMILY SSF63829 20 294 3.05E-65 T 14-10-2018 A4R43_27800 1e1dd9d0902ff84a1c4c958aae660cfc 357 Gene3D G3DSA:3.40.640.10 19 256 1.6E-37 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_27800 1e1dd9d0902ff84a1c4c958aae660cfc 357 Gene3D G3DSA:3.90.1150.10 7 344 1.6E-37 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_27800 1e1dd9d0902ff84a1c4c958aae660cfc 357 SUPERFAMILY SSF53383 7 352 8.43E-34 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_27800 1e1dd9d0902ff84a1c4c958aae660cfc 357 Pfam PF00155 Aminotransferase class I and II 43 302 7.0E-11 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_20560 f4c1636098385a7d3fade32bd6aaab78 152 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 12 142 3.8E-40 T 14-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A4R43_20560 f4c1636098385a7d3fade32bd6aaab78 152 ProSitePatterns PS00934 Glyoxalase I signature 1. 14 35 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A4R43_20560 f4c1636098385a7d3fade32bd6aaab78 152 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 127 2.5E-22 T 14-10-2018 A4R43_20560 f4c1636098385a7d3fade32bd6aaab78 152 SUPERFAMILY SSF54593 8 145 1.88E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_20560 f4c1636098385a7d3fade32bd6aaab78 152 Gene3D G3DSA:3.10.180.10 5 144 7.9E-41 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 23 470 46.236 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 Pfam PF00156 Phosphoribosyl transferase domain 291 400 3.3E-6 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 Gene3D G3DSA:3.40.50.2020 289 453 3.8E-148 T 14-10-2018 A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 24 471 1.9E-160 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 SUPERFAMILY SSF56235 24 282 9.44E-65 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 Gene3D G3DSA:3.60.20.10 24 472 3.8E-148 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 SUPERFAMILY SSF53271 265 479 1.44E-67 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 PIRSF PIRSF000485 20 482 1.3E-159 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4R43_31930 ff1e5fa5a2b27e1df78e8746c7c0d31a 512 Pfam PF13522 Glutamine amidotransferase domain 81 224 1.7E-16 T 14-10-2018 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 2.2E-52 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 2.2E-52 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 2.2E-52 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 2.2E-52 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 PRINTS PR00474 Glutamate 5-kinase family signature 215 235 2.2E-52 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 SUPERFAMILY SSF88697 279 365 1.22E-17 T 14-10-2018 IPR015947 PUA-like superfamily A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 PIRSF PIRSF000729 7 367 2.9E-117 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 Pfam PF00696 Amino acid kinase family 13 239 3.6E-40 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 SUPERFAMILY SSF53633 12 258 8.12E-58 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 SMART SM00359 280 359 2.5E-16 T 14-10-2018 IPR002478 PUA domain GO:0003723 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 263 34.88 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 365 1.9E-120 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 Gene3D G3DSA:2.30.130.10 269 366 3.1E-24 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 Pfam PF01472 PUA domain 280 349 2.2E-18 T 14-10-2018 IPR002478 PUA domain GO:0003723 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 ProSitePatterns PS00902 Glutamate 5-kinase signature. 213 230 - T 14-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4R43_39270 3c53f659fd8885047967fa8bcbed8e0e 369 Gene3D G3DSA:3.40.1160.10 1 268 4.7E-78 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4R43_41090 1e062f04307fec64780c11ddde5191f2 333 Pfam PF01368 DHH family 21 166 1.8E-11 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A4R43_41090 1e062f04307fec64780c11ddde5191f2 333 Gene3D G3DSA:3.90.1640.10 2 204 1.0E-42 T 14-10-2018 A4R43_41090 1e062f04307fec64780c11ddde5191f2 333 Pfam PF02272 DHHA1 domain 255 327 8.1E-9 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A4R43_41090 1e062f04307fec64780c11ddde5191f2 333 Gene3D G3DSA:3.10.310.30 205 328 8.3E-33 T 14-10-2018 A4R43_41090 1e062f04307fec64780c11ddde5191f2 333 SUPERFAMILY SSF64182 21 327 4.06E-47 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily A4R43_02240 4d90e921688d14ccfe97b46f4664ca86 136 SUPERFAMILY SSF51182 64 123 2.75E-7 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_02240 4d90e921688d14ccfe97b46f4664ca86 136 Gene3D G3DSA:2.60.120.10 49 128 1.8E-7 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_02500 85d97ff7de46aae6669860184df61f03 278 Gene3D G3DSA:1.10.260.40 3 83 5.5E-8 T 14-10-2018 A4R43_02500 85d97ff7de46aae6669860184df61f03 278 Gene3D G3DSA:3.30.450.180 102 264 4.7E-12 T 14-10-2018 A4R43_02500 85d97ff7de46aae6669860184df61f03 278 SMART SM00530 9 81 1.5E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_02500 85d97ff7de46aae6669860184df61f03 278 SUPERFAMILY SSF47413 27 79 1.6E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_02500 85d97ff7de46aae6669860184df61f03 278 Pfam PF13560 Helix-turn-helix domain 5 84 2.3E-19 T 14-10-2018 A4R43_04930 e3aa00ab5387dfc067e0058151b9e415 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 7.9E-20 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4R43_04930 e3aa00ab5387dfc067e0058151b9e415 76 Pfam PF03840 Preprotein translocase SecG subunit 4 72 6.3E-19 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4R43_07410 519a1d551565bda91ea622678edee6fd 442 Pfam PF13416 Bacterial extracellular solute-binding protein 69 376 1.5E-36 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_07410 519a1d551565bda91ea622678edee6fd 442 Gene3D G3DSA:3.40.190.10 172 425 1.7E-75 T 14-10-2018 A4R43_07410 519a1d551565bda91ea622678edee6fd 442 Gene3D G3DSA:3.40.190.10 76 397 1.7E-75 T 14-10-2018 A4R43_07410 519a1d551565bda91ea622678edee6fd 442 SUPERFAMILY SSF53850 44 437 6.96E-74 T 14-10-2018 A4R43_34505 677b8206687291606faf7c6b549c1e2c 319 SUPERFAMILY SSF49777 8 154 1.2E-44 T 14-10-2018 IPR036610 PEBP-like superfamily A4R43_34505 677b8206687291606faf7c6b549c1e2c 319 Gene3D G3DSA:3.30.530.20 166 318 1.1E-22 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_34505 677b8206687291606faf7c6b549c1e2c 319 Pfam PF01161 Phosphatidylethanolamine-binding protein 30 159 3.3E-35 T 14-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A4R43_34505 677b8206687291606faf7c6b549c1e2c 319 SUPERFAMILY SSF55961 162 315 6.14E-19 T 14-10-2018 A4R43_34505 677b8206687291606faf7c6b549c1e2c 319 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 167 312 1.7E-8 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_34505 677b8206687291606faf7c6b549c1e2c 319 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 32 156 6.5E-37 T 14-10-2018 IPR005247 YbhB/YbcL A4R43_34505 677b8206687291606faf7c6b549c1e2c 319 Gene3D G3DSA:3.90.280.10 1 161 3.4E-55 T 14-10-2018 IPR036610 PEBP-like superfamily A4R43_33725 d34e2c6f0f5a65645baf098075b2b6e1 390 SUPERFAMILY SSF140453 112 171 4.45E-5 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_33725 d34e2c6f0f5a65645baf098075b2b6e1 390 Gene3D G3DSA:1.10.287.1060 111 194 4.8E-5 T 14-10-2018 A4R43_25895 88d14bbec079b65f92cb85e440c79b0b 253 PIRSF PIRSF000915 1 247 2.4E-53 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4R43_25895 88d14bbec079b65f92cb85e440c79b0b 253 Gene3D G3DSA:3.40.50.1000 74 169 1.9E-76 T 14-10-2018 IPR023214 HAD superfamily A4R43_25895 88d14bbec079b65f92cb85e440c79b0b 253 Pfam PF13242 HAD-hyrolase-like 169 242 4.5E-24 T 14-10-2018 A4R43_25895 88d14bbec079b65f92cb85e440c79b0b 253 Pfam PF13344 Haloacid dehalogenase-like hydrolase 1 96 4.2E-23 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4R43_25895 88d14bbec079b65f92cb85e440c79b0b 253 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 2 218 2.4E-43 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4R43_25895 88d14bbec079b65f92cb85e440c79b0b 253 SUPERFAMILY SSF56784 1 243 3.99E-65 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_25895 88d14bbec079b65f92cb85e440c79b0b 253 Gene3D G3DSA:3.40.50.1000 1 232 1.9E-76 T 14-10-2018 IPR023214 HAD superfamily A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 SUPERFAMILY SSF46785 5 59 3.71E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 Pfam PF00455 DeoR C terminal sensor domain 76 234 2.6E-45 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 Gene3D G3DSA:1.10.10.10 8 57 1.6E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 3.7E-15 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 8.8E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 8.8E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 SMART SM00420 6 58 4.6E-16 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 SUPERFAMILY SSF100950 76 235 3.35E-29 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_25045 5f7dabd8d6a9a79baa09c436e3a79b37 262 SMART SM01134 74 236 6.8E-55 T 14-10-2018 A4R43_07300 02f27529d17073b073f839f444801531 210 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 7 205 1.6E-42 T 14-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 A4R43_07300 02f27529d17073b073f839f444801531 210 Gene3D G3DSA:1.10.3630.10 3 207 1.0E-21 T 14-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 SUPERFAMILY SSF55424 346 463 1.07E-30 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 1.2E-56 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 Gene3D G3DSA:3.50.50.60 6 332 2.6E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 Gene3D G3DSA:3.30.390.30 347 464 2.2E-29 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 327 2.4E-58 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PIRSF PIRSF000350 2 467 3.3E-73 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 454 2.6E-26 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 Gene3D G3DSA:3.50.50.60 155 273 2.6E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 9.6E-34 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 9.6E-34 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 9.6E-34 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.6E-34 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 9.6E-34 T 14-10-2018 A4R43_39385 5d28d6aac80534f69082442790ddaf72 471 SUPERFAMILY SSF51905 4 336 8.57E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_39820 d9c7a8e73ba4bb879d8acb77ec715b35 196 Pfam PF02627 Carboxymuconolactone decarboxylase family 58 124 5.3E-7 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_39820 d9c7a8e73ba4bb879d8acb77ec715b35 196 Gene3D G3DSA:1.20.1290.10 16 177 5.6E-32 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_39820 d9c7a8e73ba4bb879d8acb77ec715b35 196 SUPERFAMILY SSF69118 1 176 1.73E-39 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_22685 7de49c2366c2cf0db3879b425fa9390b 470 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_22685 7de49c2366c2cf0db3879b425fa9390b 470 Pfam PF00171 Aldehyde dehydrogenase family 11 468 2.5E-166 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_22685 7de49c2366c2cf0db3879b425fa9390b 470 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_22685 7de49c2366c2cf0db3879b425fa9390b 470 Gene3D G3DSA:3.40.605.10 7 466 3.1E-175 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_22685 7de49c2366c2cf0db3879b425fa9390b 470 SUPERFAMILY SSF53720 5 468 1.07E-161 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_22685 7de49c2366c2cf0db3879b425fa9390b 470 Gene3D G3DSA:3.40.309.10 247 438 3.1E-175 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 Gene3D G3DSA:1.10.287.130 250 323 1.7E-16 T 14-10-2018 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 470 5.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 5.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 5.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 5.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 470 6.8E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 SMART SM00388 255 322 5.2E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 Pfam PF00672 HAMP domain 196 242 2.6E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 SUPERFAMILY SSF55874 312 471 4.06E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 SUPERFAMILY SSF47384 239 322 2.94E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 SMART SM00304 195 247 2.3E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 Gene3D G3DSA:1.20.1480.50 155 249 1.5E-9 T 14-10-2018 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 SMART SM00387 364 473 1.8E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 Gene3D G3DSA:3.30.565.10 324 472 3.6E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 SUPERFAMILY SSF158472 195 244 1.44E-7 T 14-10-2018 A4R43_27585 321ada636e7ab49f1fe7128cd619b78f 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 321 1.4E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_16545 d2664f151064881a4d6b3c147a4f3fc3 170 SUPERFAMILY SSF109854 3 165 4.88E-42 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_16545 d2664f151064881a4d6b3c147a4f3fc3 170 Pfam PF04978 Protein of unknown function (DUF664) 19 166 1.0E-42 T 14-10-2018 IPR007061 Protein of unknown function DUF664 A4R43_16545 d2664f151064881a4d6b3c147a4f3fc3 170 Gene3D G3DSA:1.20.120.450 2 169 4.8E-35 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_23945 fa92ff4892c7940aae46327605b96e36 200 Gene3D G3DSA:3.40.50.150 7 196 2.4E-39 T 14-10-2018 A4R43_23945 fa92ff4892c7940aae46327605b96e36 200 SUPERFAMILY SSF53335 5 180 6.39E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_23945 fa92ff4892c7940aae46327605b96e36 200 Pfam PF13649 Methyltransferase domain 39 126 4.4E-16 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 Gene3D G3DSA:3.40.1110.10 307 438 7.6E-42 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 Pfam PF00122 E1-E2 ATPase 99 274 1.4E-34 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 9 672 39.406 T 14-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 433 444 4.5E-25 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 531 543 4.5E-25 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 455 465 4.5E-25 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 145 159 4.5E-25 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 508 527 4.5E-25 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 296 310 4.5E-25 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 11 668 2.2E-302 T 14-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 SUPERFAMILY SSF81653 103 198 1.44E-20 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 65 593 9.7E-73 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 SUPERFAMILY SSF81660 298 421 9.15E-9 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 298 304 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 SUPERFAMILY SSF81665 29 290 2.62E-12 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 SUPERFAMILY SSF56784 295 557 2.03E-37 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 Gene3D G3DSA:2.70.150.20 89 203 1.4E-26 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 Pfam PF00702 haloacid dehalogenase-like hydrolase 293 522 2.7E-31 T 14-10-2018 A4R43_18700 b355fe70091a6c7aa18499acaf3a7ba8 675 Gene3D G3DSA:3.40.50.1000 439 556 1.4E-25 T 14-10-2018 IPR023214 HAD superfamily A4R43_18985 c519b3f0219d05c7d783284d459574aa 339 Gene3D G3DSA:3.40.190.10 41 314 4.0E-67 T 14-10-2018 A4R43_18985 c519b3f0219d05c7d783284d459574aa 339 Pfam PF09084 NMT1/THI5 like 50 260 4.1E-43 T 14-10-2018 IPR015168 SsuA/THI5-like A4R43_18985 c519b3f0219d05c7d783284d459574aa 339 Gene3D G3DSA:3.40.190.10 120 223 4.0E-67 T 14-10-2018 A4R43_18985 c519b3f0219d05c7d783284d459574aa 339 SUPERFAMILY SSF53850 37 257 2.35E-35 T 14-10-2018 A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 SUPERFAMILY SSF54631 189 326 2.53E-32 T 14-10-2018 A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 SUPERFAMILY SSF56176 334 407 2.29E-14 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 Pfam PF03471 Transporter associated domain 340 415 2.1E-13 T 14-10-2018 IPR005170 Transporter-associated domain A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 Gene3D G3DSA:3.10.580.10 181 330 2.5E-53 T 14-10-2018 A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 SMART SM01091 339 421 4.1E-20 T 14-10-2018 IPR005170 Transporter-associated domain A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 Pfam PF00571 CBS domain 204 259 1.0E-5 T 14-10-2018 IPR000644 CBS domain A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 Pfam PF00571 CBS domain 269 323 8.0E-5 T 14-10-2018 IPR000644 CBS domain A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 Gene3D G3DSA:3.30.465.10 331 418 5.0E-20 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 SMART SM00116 211 260 0.0087 T 14-10-2018 IPR000644 CBS domain A4R43_39665 10df0b4cd3171d9ff0a06634847b653a 448 Pfam PF01595 Domain of unknown function DUF21 10 187 2.7E-35 T 14-10-2018 IPR002550 CNNM, transmembrane domain A4R43_18705 b6e49e5ab58c8e6e71915322477764b1 553 Pfam PF03814 Potassium-transporting ATPase A subunit 13 552 8.0E-217 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A4R43_18705 b6e49e5ab58c8e6e71915322477764b1 553 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 552 3.3E-193 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A4R43_18705 b6e49e5ab58c8e6e71915322477764b1 553 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 553 31.533 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A4R43_18705 b6e49e5ab58c8e6e71915322477764b1 553 PIRSF PIRSF001294 3 553 2.7E-206 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 9.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 9.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 9.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 SUPERFAMILY SSF51735 4 251 2.29E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_39090 489bbec1610571d43cb35f11c602d781 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_39090 489bbec1610571d43cb35f11c602d781 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 248 4.3E-46 T 14-10-2018 A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.5E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.5E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.5E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 4.5E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.5E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.5E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39090 489bbec1610571d43cb35f11c602d781 253 Gene3D G3DSA:3.40.50.720 2 252 1.5E-64 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 2.3E-14 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 2.3E-14 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.3E-14 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 2.3E-14 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 Pfam PF14759 Reductase C-terminal 320 396 3.1E-28 T 14-10-2018 IPR028202 Reductase, C-terminal A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 Gene3D G3DSA:3.50.50.60 114 238 1.0E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 Gene3D G3DSA:3.50.50.60 7 302 1.0E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 Gene3D G3DSA:3.30.390.30 320 399 6.8E-29 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 SUPERFAMILY SSF55424 312 395 3.43E-26 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 SUPERFAMILY SSF51905 3 191 5.1E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 SUPERFAMILY SSF51905 145 310 1.41E-31 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 6.3E-19 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 6.3E-19 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.3E-19 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 6.3E-19 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 6.3E-19 T 14-10-2018 A4R43_29830 d4e24f36ee096b8458163fb858c53037 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 301 7.4E-58 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_00425 bb86ee7c33aab74175c990a41b3fb09b 247 SUPERFAMILY SSF48008 93 238 3.4E-19 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_00425 bb86ee7c33aab74175c990a41b3fb09b 247 SUPERFAMILY SSF46785 20 96 1.71E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00425 bb86ee7c33aab74175c990a41b3fb09b 247 Pfam PF07729 FCD domain 97 233 9.3E-20 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_00425 bb86ee7c33aab74175c990a41b3fb09b 247 Gene3D G3DSA:1.20.120.530 87 242 7.3E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_00425 bb86ee7c33aab74175c990a41b3fb09b 247 SMART SM00895 97 234 2.3E-11 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_00425 bb86ee7c33aab74175c990a41b3fb09b 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 86 5.7E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_00425 bb86ee7c33aab74175c990a41b3fb09b 247 SMART SM00345 28 86 1.6E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_00425 bb86ee7c33aab74175c990a41b3fb09b 247 Gene3D G3DSA:1.10.10.10 21 86 2.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35530 118933b6e7fd433234a60c551dd8752a 324 Gene3D G3DSA:1.40.20.10 24 320 1.1E-59 T 14-10-2018 IPR038186 CHAD domain superfamily A4R43_35530 118933b6e7fd433234a60c551dd8752a 324 Pfam PF05235 CHAD domain 38 274 1.3E-50 T 14-10-2018 IPR007899 CHAD domain A4R43_35530 118933b6e7fd433234a60c551dd8752a 324 SMART SM00880 37 307 6.8E-52 T 14-10-2018 IPR007899 CHAD domain A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 Pfam PF04542 Sigma-70 region 2 41 110 2.1E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 Gene3D G3DSA:1.20.120.1810 3 109 5.8E-16 T 14-10-2018 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 Pfam PF04539 Sigma-70 region 3 123 187 9.2E-14 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 SUPERFAMILY SSF88946 25 110 4.97E-27 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 Gene3D G3DSA:1.10.10.10 111 163 7.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 Pfam PF04545 Sigma-70, region 4 207 255 3.0E-18 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 Gene3D G3DSA:1.10.10.10 184 260 1.7E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 258 3.1E-36 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 35 258 1.3E-91 T 14-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 PRINTS PR00046 Major sigma-70 factor signature 65 78 6.6E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 PRINTS PR00046 Major sigma-70 factor signature 211 223 6.6E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 PRINTS PR00046 Major sigma-70 factor signature 228 243 6.6E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 PRINTS PR00046 Major sigma-70 factor signature 243 254 6.6E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 SUPERFAMILY SSF88659 114 188 6.1E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_06250 09a3c230cbdba941b1dca9d361d8aa0c 262 SUPERFAMILY SSF88659 192 258 2.06E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_11350 f6149eeb6f21d83db9ef287cf86a2e8a 294 Gene3D G3DSA:3.20.20.30 1 292 2.3E-53 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_11350 f6149eeb6f21d83db9ef287cf86a2e8a 294 Pfam PF00296 Luciferase-like monooxygenase 1 269 6.7E-36 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_11350 f6149eeb6f21d83db9ef287cf86a2e8a 294 SUPERFAMILY SSF51679 1 287 1.83E-48 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_07500 24939d39fed36e7df46879ebe46d003b 402 SUPERFAMILY SSF53756 1 387 1.59E-91 T 14-10-2018 A4R43_07500 24939d39fed36e7df46879ebe46d003b 402 Pfam PF13439 Glycosyltransferase Family 4 21 197 7.1E-35 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_07500 24939d39fed36e7df46879ebe46d003b 402 Gene3D G3DSA:3.40.50.2000 193 367 1.3E-122 T 14-10-2018 A4R43_07500 24939d39fed36e7df46879ebe46d003b 402 Pfam PF00534 Glycosyl transferases group 1 208 354 2.9E-37 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_07500 24939d39fed36e7df46879ebe46d003b 402 Gene3D G3DSA:3.40.50.2000 5 384 1.3E-122 T 14-10-2018 A4R43_41310 db01641d38658d5b19dbcd1169a40807 150 Gene3D G3DSA:1.10.260.40 3 76 3.2E-16 T 14-10-2018 A4R43_41310 db01641d38658d5b19dbcd1169a40807 150 SUPERFAMILY SSF47413 3 69 1.58E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_41310 db01641d38658d5b19dbcd1169a40807 150 SMART SM00530 12 67 5.5E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_41310 db01641d38658d5b19dbcd1169a40807 150 Pfam PF12844 Helix-turn-helix domain 10 71 3.0E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_00375 a45dd845ba0ba72cdc76753f50eed72e 208 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 4 201 8.9E-69 T 14-10-2018 IPR017519 Conserved hypothetical protein CHP03085 A4R43_00375 a45dd845ba0ba72cdc76753f50eed72e 208 SUPERFAMILY SSF109854 3 113 1.28E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_00375 a45dd845ba0ba72cdc76753f50eed72e 208 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 4 184 2.6E-30 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_33735 44bd8518af9d5e280cf2e52822218b06 189 Pfam PF02575 YbaB/EbfC DNA-binding family 28 105 3.7E-8 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_33735 44bd8518af9d5e280cf2e52822218b06 189 Gene3D G3DSA:3.30.1310.10 2 114 6.2E-6 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_33735 44bd8518af9d5e280cf2e52822218b06 189 SUPERFAMILY SSF82607 28 104 1.07E-6 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_27280 8b5793af387332130598f1fd5499e0b3 158 Pfam PF00210 Ferritin-like domain 20 156 1.7E-22 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A4R43_27280 8b5793af387332130598f1fd5499e0b3 158 ProSitePatterns PS00818 Dps protein family signature 1. 40 56 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A4R43_27280 8b5793af387332130598f1fd5499e0b3 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 135 153 1.2E-10 T 14-10-2018 IPR002177 DNA-binding protein Dps A4R43_27280 8b5793af387332130598f1fd5499e0b3 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 40 56 1.2E-10 T 14-10-2018 IPR002177 DNA-binding protein Dps A4R43_27280 8b5793af387332130598f1fd5499e0b3 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 64 80 1.2E-10 T 14-10-2018 IPR002177 DNA-binding protein Dps A4R43_27280 8b5793af387332130598f1fd5499e0b3 158 Gene3D G3DSA:1.20.1260.10 2 158 1.2E-44 T 14-10-2018 IPR012347 Ferritin-like A4R43_27280 8b5793af387332130598f1fd5499e0b3 158 SUPERFAMILY SSF47240 7 155 2.65E-45 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_27280 8b5793af387332130598f1fd5499e0b3 158 PIRSF PIRSF005900 2 158 3.8E-43 T 14-10-2018 IPR002177 DNA-binding protein Dps A4R43_02620 3449d6b49881ab3ae5db547bad5aa0d5 230 Pfam PF00072 Response regulator receiver domain 3 119 1.3E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_02620 3449d6b49881ab3ae5db547bad5aa0d5 230 SMART SM00448 1 118 2.3E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_02620 3449d6b49881ab3ae5db547bad5aa0d5 230 Gene3D G3DSA:3.40.50.2300 1 127 2.4E-36 T 14-10-2018 A4R43_02620 3449d6b49881ab3ae5db547bad5aa0d5 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 1.4E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_02620 3449d6b49881ab3ae5db547bad5aa0d5 230 Gene3D G3DSA:1.10.10.10 128 229 1.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02620 3449d6b49881ab3ae5db547bad5aa0d5 230 SUPERFAMILY SSF52172 2 179 4.68E-36 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_02620 3449d6b49881ab3ae5db547bad5aa0d5 230 SMART SM00862 151 226 2.9E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_33405 24e943eb8dbd450c0eaebb962d5bfa72 385 Gene3D G3DSA:2.120.10.10 30 369 5.8E-82 T 14-10-2018 A4R43_33405 24e943eb8dbd450c0eaebb962d5bfa72 385 SUPERFAMILY SSF50939 41 262 3.53E-11 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_15970 d60fe90e82f18ee13d5617780ecefad0 265 SUPERFAMILY SSF53474 4 261 6.27E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_15970 d60fe90e82f18ee13d5617780ecefad0 265 Gene3D G3DSA:3.40.50.1820 4 261 4.7E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_15970 d60fe90e82f18ee13d5617780ecefad0 265 Pfam PF00561 alpha/beta hydrolase fold 22 141 3.4E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_20510 425089ba473129cd3645c1328d523fc7 351 Pfam PF02653 Branched-chain amino acid transport system / permease component 64 338 2.7E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_14550 3e24ee41b0f874fe683b2ff57c28de46 257 SUPERFAMILY SSF52540 7 251 1.89E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14550 3e24ee41b0f874fe683b2ff57c28de46 257 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_14550 3e24ee41b0f874fe683b2ff57c28de46 257 Pfam PF00005 ABC transporter 23 181 5.3E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14550 3e24ee41b0f874fe683b2ff57c28de46 257 PIRSF PIRSF039085 4 257 7.9E-117 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4R43_14550 3e24ee41b0f874fe683b2ff57c28de46 257 SMART SM00382 32 229 6.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14550 3e24ee41b0f874fe683b2ff57c28de46 257 Gene3D G3DSA:3.40.50.300 5 256 1.2E-77 T 14-10-2018 A4R43_02540 97be88d5c7648ccf9b1c5a17df859015 343 SUPERFAMILY SSF47413 1 59 1.22E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_02540 97be88d5c7648ccf9b1c5a17df859015 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 48 6.8E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_02540 97be88d5c7648ccf9b1c5a17df859015 343 SUPERFAMILY SSF53822 73 342 1.26E-68 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_02540 97be88d5c7648ccf9b1c5a17df859015 343 SMART SM00354 1 70 1.7E-25 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_02540 97be88d5c7648ccf9b1c5a17df859015 343 Gene3D G3DSA:3.40.50.2300 173 302 2.9E-71 T 14-10-2018 A4R43_02540 97be88d5c7648ccf9b1c5a17df859015 343 Gene3D G3DSA:1.10.260.40 1 55 4.6E-23 T 14-10-2018 A4R43_02540 97be88d5c7648ccf9b1c5a17df859015 343 Pfam PF13377 Periplasmic binding protein-like domain 181 341 3.7E-41 T 14-10-2018 A4R43_02540 97be88d5c7648ccf9b1c5a17df859015 343 Gene3D G3DSA:3.40.50.2300 56 319 2.9E-71 T 14-10-2018 A4R43_19220 06c8c81d69fd21b0c8e0b1340e225ef0 328 SUPERFAMILY SSF53822 47 318 9.42E-49 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_19220 06c8c81d69fd21b0c8e0b1340e225ef0 328 Gene3D G3DSA:3.40.50.2300 151 311 6.7E-74 T 14-10-2018 A4R43_19220 06c8c81d69fd21b0c8e0b1340e225ef0 328 Pfam PF13407 Periplasmic binding protein domain 48 291 2.3E-35 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_19220 06c8c81d69fd21b0c8e0b1340e225ef0 328 Gene3D G3DSA:3.40.50.2300 57 309 6.7E-74 T 14-10-2018 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 SUPERFAMILY SSF48179 181 334 5.92E-52 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 SUPERFAMILY SSF51735 5 181 2.47E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 Gene3D G3DSA:3.40.50.720 1 189 5.4E-62 T 14-10-2018 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 190 211 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 6 162 2.0E-50 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 182 321 2.4E-50 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 4 325 36.298 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 Gene3D G3DSA:1.10.1040.10 191 336 1.9E-49 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 PIRSF PIRSF000114 1 335 2.0E-99 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 200 224 1.1E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 58 85 1.1E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 175 199 1.1E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 1.1E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 8 25 1.1E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_19555 1510a8419f0ff1c98fdbc3f83b06b644 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 240 257 1.1E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4R43_00385 fa58ef52d235c418f2a29fc736e61f69 188 Gene3D G3DSA:1.10.260.40 1 76 1.5E-16 T 14-10-2018 A4R43_00385 fa58ef52d235c418f2a29fc736e61f69 188 Pfam PF01381 Helix-turn-helix 17 68 4.6E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_00385 fa58ef52d235c418f2a29fc736e61f69 188 SUPERFAMILY SSF51182 63 186 2.8E-16 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_00385 fa58ef52d235c418f2a29fc736e61f69 188 SMART SM00530 15 70 7.6E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_00385 fa58ef52d235c418f2a29fc736e61f69 188 Gene3D G3DSA:2.60.120.10 97 187 1.2E-16 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_00385 fa58ef52d235c418f2a29fc736e61f69 188 SUPERFAMILY SSF47413 10 75 2.59E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_06105 53690ebb398163cb0eb3b49f9dc3acb7 208 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 1 207 1.8E-59 T 14-10-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit A4R43_06105 53690ebb398163cb0eb3b49f9dc3acb7 208 Gene3D G3DSA:1.20.1300.10 1 208 1.0E-41 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_06105 53690ebb398163cb0eb3b49f9dc3acb7 208 SUPERFAMILY SSF81343 1 207 1.64E-46 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 SUPERFAMILY SSF46894 138 208 9.86E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 1.9E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 Pfam PF00072 Response regulator receiver domain 6 118 1.4E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 Gene3D G3DSA:3.40.50.12740 4 208 8.8E-49 T 14-10-2018 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 SUPERFAMILY SSF52172 4 131 2.13E-24 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 9.5E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 9.5E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 9.5E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 SMART SM00448 4 117 3.6E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 SMART SM00421 145 202 2.8E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05435 5a446b8fd5661aa7627c042000968e46 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_16570 48b1336f2bbcbf04fc0809d85090f639 488 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 363 387 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_16570 48b1336f2bbcbf04fc0809d85090f639 488 Pfam PF01098 Cell cycle protein 51 405 4.5E-104 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_16570 48b1336f2bbcbf04fc0809d85090f639 488 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 51 404 2.4E-107 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 SMART SM00382 31 228 3.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 SMART SM00382 287 481 0.0093 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 Gene3D G3DSA:3.40.50.300 2 254 8.4E-58 T 14-10-2018 A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 SUPERFAMILY SSF52540 265 490 2.62E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 Pfam PF00005 ABC transporter 278 432 1.1E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 Gene3D G3DSA:3.40.50.300 263 504 1.6E-46 T 14-10-2018 A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 Pfam PF00005 ABC transporter 22 172 2.2E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_22560 b856680e1f61c1281c26f8ffef7a15b6 506 SUPERFAMILY SSF52540 5 230 2.92E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25585 2a8b61ff8c385336c0175ea8737785ed 229 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 199 212 - T 14-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_25585 2a8b61ff8c385336c0175ea8737785ed 229 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 189 229 1.8E-18 T 14-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_25585 2a8b61ff8c385336c0175ea8737785ed 229 SUPERFAMILY SSF50475 30 229 2.48E-64 T 14-10-2018 A4R43_25585 2a8b61ff8c385336c0175ea8737785ed 229 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 49 132 9.3E-20 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_25585 2a8b61ff8c385336c0175ea8737785ed 229 Gene3D G3DSA:2.30.110.10 26 229 2.4E-78 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_25585 2a8b61ff8c385336c0175ea8737785ed 229 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 26 229 36.228 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_25585 2a8b61ff8c385336c0175ea8737785ed 229 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 18 229 6.1E-74 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_25585 2a8b61ff8c385336c0175ea8737785ed 229 PIRSF PIRSF000190 16 229 1.0E-77 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 SUPERFAMILY SSF49998 196 610 1.96E-151 T 14-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 SUPERFAMILY SSF54416 2 83 8.18E-16 T 14-10-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 Gene3D G3DSA:3.10.450.40 92 194 8.0E-26 T 14-10-2018 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 Pfam PF01179 Copper amine oxidase, enzyme domain 207 608 2.2E-151 T 14-10-2018 IPR015798 Copper amine oxidase, catalytic domain GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 Pfam PF02728 Copper amine oxidase, N3 domain 88 189 4.4E-17 T 14-10-2018 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 ProSitePatterns PS01164 Copper amine oxidase topaquinone signature. 352 365 - T 14-10-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 SUPERFAMILY SSF54416 87 195 5.23E-26 T 14-10-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 Gene3D G3DSA:2.70.98.20 196 609 3.0E-159 T 14-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 A4R43_13430 62a3f83054f08532cdc2ccc5cc0f081a 634 Gene3D G3DSA:3.10.450.40 1 86 3.6E-9 T 14-10-2018 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 258 368 4.2E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 SUPERFAMILY SSF47384 139 211 2.16E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 Gene3D G3DSA:1.10.287.130 141 212 1.3E-16 T 14-10-2018 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 SMART SM00387 258 370 1.1E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 SUPERFAMILY SSF55874 203 372 1.57E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 SMART SM00388 147 213 8.8E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 Pfam PF00512 His Kinase A (phospho-acceptor) domain 148 212 1.3E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 323 1.1E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 367 1.1E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 1.1E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 309 1.1E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_32790 9a7c1119524256ba0e1e077d7781f170 410 Gene3D G3DSA:3.30.565.10 220 375 7.1E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_24605 8abca6a470cb8374523ac0e877842b16 422 SUPERFAMILY SSF47413 9 63 1.52E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_24605 8abca6a470cb8374523ac0e877842b16 422 Pfam PF13560 Helix-turn-helix domain 9 66 2.6E-9 T 14-10-2018 A4R43_24605 8abca6a470cb8374523ac0e877842b16 422 SMART SM00530 8 63 2.9E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_24605 8abca6a470cb8374523ac0e877842b16 422 SUPERFAMILY SSF48452 232 411 5.81E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_24605 8abca6a470cb8374523ac0e877842b16 422 Gene3D G3DSA:1.10.260.40 9 69 1.0E-12 T 14-10-2018 A4R43_25430 8b3513fd39357d64adb4de42f7a49f5a 228 Gene3D G3DSA:3.90.470.20 107 213 3.1E-36 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A4R43_25430 8b3513fd39357d64adb4de42f7a49f5a 228 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 107 174 1.6E-12 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A4R43_25430 8b3513fd39357d64adb4de42f7a49f5a 228 SUPERFAMILY SSF56214 106 216 2.09E-20 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A4R43_25430 8b3513fd39357d64adb4de42f7a49f5a 228 Gene3D G3DSA:3.90.470.20 19 216 3.1E-36 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A4R43_25430 8b3513fd39357d64adb4de42f7a49f5a 228 SUPERFAMILY SSF56214 18 99 5.49E-14 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A4R43_26325 10d2d587c6ba6909bda660e92e5c2725 281 PIRSF PIRSF006648 4 281 2.0E-72 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_26325 10d2d587c6ba6909bda660e92e5c2725 281 Pfam PF01061 ABC-2 type transporter 39 246 2.0E-26 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_17320 433479afcad5aa2d9b524bf080790a52 273 Gene3D G3DSA:1.10.3720.10 63 259 1.5E-19 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_17320 433479afcad5aa2d9b524bf080790a52 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 250 3.1E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_17320 433479afcad5aa2d9b524bf080790a52 273 SUPERFAMILY SSF161098 65 244 7.85E-25 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 5 518 52.926 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 204 518 5.6E-144 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 Gene3D G3DSA:3.40.50.620 201 397 1.2E-69 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 Gene3D G3DSA:3.30.300.10 398 518 4.1E-51 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00097 Anthranilate synthase component II signature 52 61 3.3E-5 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00097 Anthranilate synthase component II signature 168 181 3.3E-5 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00097 Anthranilate synthase component II signature 79 90 3.3E-5 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 3.0E-8 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 3.0E-8 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 3.0E-8 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 8 194 7.7E-72 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 Gene3D G3DSA:3.40.50.880 6 200 6.3E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 SUPERFAMILY SSF52402 184 438 1.92E-54 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 SUPERFAMILY SSF52317 8 228 8.34E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 2.0E-7 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 2.0E-7 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 8 22 2.0E-7 T 14-10-2018 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 Pfam PF02540 NAD synthase 211 279 6.6E-6 T 14-10-2018 IPR022310 NAD/GMP synthase A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 Pfam PF00117 Glutamine amidotransferase class-I 10 191 3.5E-41 T 14-10-2018 IPR017926 Glutamine amidotransferase A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 Pfam PF00958 GMP synthase C terminal domain 425 517 1.1E-38 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4R43_34375 9ccfa57eaf53bef4a91cd7ea4e4af1b1 518 SUPERFAMILY SSF54810 397 518 1.05E-45 T 14-10-2018 A4R43_06770 15779b9c6379b23ca4f9cadc06595bce 329 SMART SM00382 38 231 7.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_06770 15779b9c6379b23ca4f9cadc06595bce 329 SUPERFAMILY SSF52540 22 253 7.67E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06770 15779b9c6379b23ca4f9cadc06595bce 329 Gene3D G3DSA:3.40.50.300 2 323 1.1E-88 T 14-10-2018 A4R43_06770 15779b9c6379b23ca4f9cadc06595bce 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 315 3.0E-21 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_06770 15779b9c6379b23ca4f9cadc06595bce 329 Pfam PF00005 ABC transporter 29 182 6.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_06770 15779b9c6379b23ca4f9cadc06595bce 329 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_06770 15779b9c6379b23ca4f9cadc06595bce 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 296 2.8E-13 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_02765 41a74c62268b2a888a63e2de487e9046 406 SUPERFAMILY SSF50952 53 397 2.75E-33 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_02765 41a74c62268b2a888a63e2de487e9046 406 Gene3D G3DSA:2.120.10.30 46 397 3.1E-84 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_02765 41a74c62268b2a888a63e2de487e9046 406 Pfam PF07995 Glucose / Sorbosone dehydrogenase 60 388 1.3E-41 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_25365 89b988e2d067f5b43596fc6eb632f85e 167 Gene3D G3DSA:1.10.3300.10 9 167 7.2E-18 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_25365 89b988e2d067f5b43596fc6eb632f85e 167 Pfam PF07336 Putative stress-induced transcription regulator 13 104 6.9E-9 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator A4R43_25365 89b988e2d067f5b43596fc6eb632f85e 167 Pfam PF11706 CGNR zinc finger 123 165 2.7E-17 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_25365 89b988e2d067f5b43596fc6eb632f85e 167 SUPERFAMILY SSF160904 11 165 6.02E-33 T 14-10-2018 A4R43_02705 dd1fffac9bc422b51e71682bcf1880e5 193 Gene3D G3DSA:3.40.50.1820 2 192 1.5E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02705 dd1fffac9bc422b51e71682bcf1880e5 193 SUPERFAMILY SSF53474 4 191 2.0E-14 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02705 dd1fffac9bc422b51e71682bcf1880e5 193 Pfam PF01738 Dienelactone hydrolase family 4 191 1.0E-8 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 A4R43_15030 83b1d313946537452607973f7a559401 202 SUPERFAMILY SSF52172 2 130 1.71E-30 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_15030 83b1d313946537452607973f7a559401 202 Pfam PF00072 Response regulator receiver domain 6 116 5.7E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15030 83b1d313946537452607973f7a559401 202 SMART SM00448 3 116 1.9E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15030 83b1d313946537452607973f7a559401 202 SUPERFAMILY SSF46894 127 202 1.77E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_15030 83b1d313946537452607973f7a559401 202 SMART SM00421 139 196 3.0E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15030 83b1d313946537452607973f7a559401 202 Gene3D G3DSA:3.40.50.12740 3 201 9.8E-56 T 14-10-2018 A4R43_15030 83b1d313946537452607973f7a559401 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 2.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15030 83b1d313946537452607973f7a559401 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 2.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15030 83b1d313946537452607973f7a559401 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 2.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_15030 83b1d313946537452607973f7a559401 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 195 2.7E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 Pfam PF06827 Zinc finger found in FPG and IleRS 256 281 1.5E-6 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 281 40.322 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 SUPERFAMILY SSF81624 2 149 7.59E-36 T 14-10-2018 IPR035937 MutM-like, N-terminal A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 SMART SM01232 140 232 5.8E-38 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 SUPERFAMILY SSF46946 140 229 3.83E-24 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 119 1.3E-36 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 140 227 9.1E-22 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 Gene3D G3DSA:3.20.190.10 2 130 4.3E-38 T 14-10-2018 IPR035937 MutM-like, N-terminal A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 Gene3D G3DSA:1.10.8.50 142 282 4.8E-42 T 14-10-2018 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 SUPERFAMILY SSF57716 232 281 1.23E-14 T 14-10-2018 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 SMART SM00898 2 121 2.4E-48 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4R43_18755 b6a5164318ed0c7df494621c64404a15 288 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 280 7.1E-89 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 Pfam PF00575 S1 RNA binding domain 297 369 2.2E-21 T 14-10-2018 IPR003029 S1 domain GO:0003676 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 Pfam PF00575 S1 RNA binding domain 39 111 1.2E-15 T 14-10-2018 IPR003029 S1 domain GO:0003676 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 Pfam PF00575 S1 RNA binding domain 213 283 5.6E-26 T 14-10-2018 IPR003029 S1 domain GO:0003676 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 Pfam PF00575 S1 RNA binding domain 127 194 1.3E-13 T 14-10-2018 IPR003029 S1 domain GO:0003676 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 SMART SM00316 298 369 1.0E-22 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 SMART SM00316 40 111 3.2E-17 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 SMART SM00316 127 194 1.6E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 SMART SM00316 213 283 8.9E-28 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 Gene3D G3DSA:2.40.50.140 210 289 4.0E-30 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 Gene3D G3DSA:2.40.50.140 290 373 7.2E-28 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 SUPERFAMILY SSF50249 113 197 3.36E-14 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 SUPERFAMILY SSF50249 34 136 1.12E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 352 370 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 235 256 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 60 74 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 149 166 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 178 198 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 313 332 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 132 148 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 108 127 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 PRINTS PR00681 Ribosomal protein S1 signature 42 60 1.7E-87 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 SUPERFAMILY SSF50249 213 295 3.98E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 Gene3D G3DSA:2.40.50.140 124 206 1.2E-10 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 Gene3D G3DSA:2.40.50.140 28 123 4.3E-23 T 14-10-2018 A4R43_14790 3349342ca5fe5a23164f2d1668a23194 500 SUPERFAMILY SSF50249 283 371 3.29E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_06115 6cf1c1eeaff11cdfe20c095cb92c65e7 293 PIRSF PIRSF037505 4 214 1.1E-6 T 14-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 A4R43_06115 6cf1c1eeaff11cdfe20c095cb92c65e7 293 PIRSF PIRSF037505 233 293 0.5 T 14-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 A4R43_06115 6cf1c1eeaff11cdfe20c095cb92c65e7 293 Pfam PF02574 Homocysteine S-methyltransferase 8 288 6.5E-70 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4R43_06115 6cf1c1eeaff11cdfe20c095cb92c65e7 293 Gene3D G3DSA:3.20.20.330 2 287 1.4E-92 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A4R43_06115 6cf1c1eeaff11cdfe20c095cb92c65e7 293 SUPERFAMILY SSF82282 6 291 5.1E-75 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A4R43_34985 d3d71f9961f719c49f5877b0c69af159 432 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 63 419 2.5E-100 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 A4R43_34985 d3d71f9961f719c49f5877b0c69af159 432 Gene3D G3DSA:3.40.630.10 62 416 1.2E-111 T 14-10-2018 A4R43_34985 d3d71f9961f719c49f5877b0c69af159 432 Pfam PF01546 Peptidase family M20/M25/M40 118 427 2.4E-30 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_34985 d3d71f9961f719c49f5877b0c69af159 432 PIRSF PIRSF005962 51 432 1.5E-100 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 A4R43_34985 d3d71f9961f719c49f5877b0c69af159 432 Gene3D G3DSA:3.30.70.360 226 340 1.2E-111 T 14-10-2018 A4R43_34985 d3d71f9961f719c49f5877b0c69af159 432 SUPERFAMILY SSF55031 227 344 7.48E-20 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_34985 d3d71f9961f719c49f5877b0c69af159 432 SUPERFAMILY SSF53187 52 431 6.91E-74 T 14-10-2018 A4R43_13400 d37eafc77b0a0741fc85dfea1c614e34 390 Pfam PF13458 Periplasmic binding protein 28 370 1.3E-49 T 14-10-2018 IPR028081 Leucine-binding protein domain A4R43_13400 d37eafc77b0a0741fc85dfea1c614e34 390 Gene3D G3DSA:3.40.50.2300 40 340 9.1E-42 T 14-10-2018 A4R43_13400 d37eafc77b0a0741fc85dfea1c614e34 390 Gene3D G3DSA:3.40.50.2300 146 275 9.1E-42 T 14-10-2018 A4R43_13400 d37eafc77b0a0741fc85dfea1c614e34 390 SUPERFAMILY SSF53822 28 364 1.24E-47 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_41785 ed3e3c8419a4ca2b430ae5df7abfc129 128 Gene3D G3DSA:1.10.10.10 13 122 2.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41785 ed3e3c8419a4ca2b430ae5df7abfc129 128 SMART SM00345 19 78 8.2E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_41785 ed3e3c8419a4ca2b430ae5df7abfc129 128 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 78 6.1E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_41785 ed3e3c8419a4ca2b430ae5df7abfc129 128 SUPERFAMILY SSF46785 8 98 9.56E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26040 be4730f1847b432278c19f74369f4210 323 Pfam PF00107 Zinc-binding dehydrogenase 174 284 1.0E-8 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_26040 be4730f1847b432278c19f74369f4210 323 SUPERFAMILY SSF51735 143 289 9.53E-16 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_26040 be4730f1847b432278c19f74369f4210 323 SUPERFAMILY SSF50129 1 171 4.4E-34 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_26040 be4730f1847b432278c19f74369f4210 323 Gene3D G3DSA:3.90.180.10 18 311 8.4E-54 T 14-10-2018 A4R43_26040 be4730f1847b432278c19f74369f4210 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 130 7.0E-17 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_26040 be4730f1847b432278c19f74369f4210 323 Gene3D G3DSA:3.40.50.720 150 267 8.4E-54 T 14-10-2018 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 SUPERFAMILY SSF52440 2 101 2.01E-30 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 408 7.5E-26 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 SUPERFAMILY SSF56059 102 310 3.72E-51 T 14-10-2018 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 39.237 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 Gene3D G3DSA:3.30.470.20 183 320 1.5E-51 T 14-10-2018 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 SMART SM01210 322 411 7.7E-38 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 Gene3D G3DSA:3.90.600.10 322 408 7.5E-26 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 7.5E-30 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 SMART SM01209 101 287 2.1E-107 T 14-10-2018 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 Gene3D G3DSA:3.30.1490.20 121 182 1.9E-10 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 287 3.9E-67 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 14-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 SUPERFAMILY SSF51246 321 411 1.67E-23 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 411 3.0E-146 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31680 9894eecb473fe5594a86e663eb348b6f 420 Gene3D G3DSA:3.40.50.20 2 93 3.8E-31 T 14-10-2018 A4R43_28065 92cdf46df8b79afa0b5c3acca312fd0f 272 SUPERFAMILY SSF53335 49 248 3.61E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_28065 92cdf46df8b79afa0b5c3acca312fd0f 272 Pfam PF13578 Methyltransferase domain 117 227 7.4E-10 T 14-10-2018 A4R43_28065 92cdf46df8b79afa0b5c3acca312fd0f 272 Gene3D G3DSA:3.40.50.150 22 264 1.0E-38 T 14-10-2018 A4R43_30875 5494b4db9d7725ca2cb453aafc09ce37 147 SUPERFAMILY SSF46785 8 137 2.15E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_30875 5494b4db9d7725ca2cb453aafc09ce37 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 4.7E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_30875 5494b4db9d7725ca2cb453aafc09ce37 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 4.7E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_30875 5494b4db9d7725ca2cb453aafc09ce37 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 4.7E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_30875 5494b4db9d7725ca2cb453aafc09ce37 147 Pfam PF12802 MarR family 31 84 1.0E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_30875 5494b4db9d7725ca2cb453aafc09ce37 147 SMART SM00347 25 124 7.0E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_30875 5494b4db9d7725ca2cb453aafc09ce37 147 Gene3D G3DSA:1.10.10.10 2 142 9.0E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41350 619f8725b1c427ad33c8ca50a4fe51e6 299 Pfam PF13614 AAA domain 3 181 5.5E-33 T 14-10-2018 IPR025669 AAA domain A4R43_41350 619f8725b1c427ad33c8ca50a4fe51e6 299 SUPERFAMILY SSF52540 2 256 3.27E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41350 619f8725b1c427ad33c8ca50a4fe51e6 299 Gene3D G3DSA:3.40.50.300 1 270 1.8E-59 T 14-10-2018 A4R43_27575 1055294ba8ebb6aa939c28f9c52e4a65 296 SUPERFAMILY SSF48317 42 229 6.8E-20 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4R43_27575 1055294ba8ebb6aa939c28f9c52e4a65 296 Gene3D G3DSA:1.20.144.10 146 242 1.3E-15 T 14-10-2018 A4R43_27575 1055294ba8ebb6aa939c28f9c52e4a65 296 Pfam PF01569 PAP2 superfamily 140 230 1.0E-12 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_27575 1055294ba8ebb6aa939c28f9c52e4a65 296 SMART SM00014 117 224 0.0023 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_09780 b66fd2a50f5fb3ae02833f05c431e8fd 257 SUPERFAMILY SSF53850 33 205 4.02E-23 T 14-10-2018 A4R43_09780 b66fd2a50f5fb3ae02833f05c431e8fd 257 Gene3D G3DSA:3.40.190.290 20 129 1.0E-16 T 14-10-2018 A4R43_09780 b66fd2a50f5fb3ae02833f05c431e8fd 257 Gene3D G3DSA:3.40.190.10 183 204 1.2E-8 T 14-10-2018 A4R43_09780 b66fd2a50f5fb3ae02833f05c431e8fd 257 Pfam PF03466 LysR substrate binding domain 34 204 9.7E-24 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_09780 b66fd2a50f5fb3ae02833f05c431e8fd 257 Gene3D G3DSA:3.40.190.10 139 182 1.2E-8 T 14-10-2018 A4R43_37495 5a594ef8d927ea7a77c950a831f9aa73 215 Gene3D G3DSA:3.40.50.2300 1 117 7.0E-26 T 14-10-2018 A4R43_37495 5a594ef8d927ea7a77c950a831f9aa73 215 SMART SM00862 140 212 1.5E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37495 5a594ef8d927ea7a77c950a831f9aa73 215 SMART SM00448 1 107 1.7E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_37495 5a594ef8d927ea7a77c950a831f9aa73 215 SUPERFAMILY SSF52172 1 113 4.7E-25 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_37495 5a594ef8d927ea7a77c950a831f9aa73 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 212 2.9E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37495 5a594ef8d927ea7a77c950a831f9aa73 215 SUPERFAMILY SSF46894 117 213 1.39E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37495 5a594ef8d927ea7a77c950a831f9aa73 215 Gene3D G3DSA:1.10.10.10 118 215 3.0E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37495 5a594ef8d927ea7a77c950a831f9aa73 215 Pfam PF00072 Response regulator receiver domain 1 107 5.1E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_34955 043db95378ab9cdd7119e2ed153e6f2b 262 Gene3D G3DSA:3.40.50.1580 1 261 2.2E-89 T 14-10-2018 A4R43_34955 043db95378ab9cdd7119e2ed153e6f2b 262 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 77 118 - T 14-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A4R43_34955 043db95378ab9cdd7119e2ed153e6f2b 262 SUPERFAMILY SSF53167 4 259 6.54E-79 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A4R43_34955 043db95378ab9cdd7119e2ed153e6f2b 262 PIRSF PIRSF000477 1 262 7.0E-91 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A4R43_34955 043db95378ab9cdd7119e2ed153e6f2b 262 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 23 259 4.1E-99 T 14-10-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A4R43_34955 043db95378ab9cdd7119e2ed153e6f2b 262 Pfam PF01048 Phosphorylase superfamily 23 259 1.2E-40 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4R43_34955 043db95378ab9cdd7119e2ed153e6f2b 262 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 23 259 2.8E-78 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A4R43_04055 cc4c6eb3895b25a87c52adf20da5cf9a 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 290 1.1E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_04055 cc4c6eb3895b25a87c52adf20da5cf9a 303 Gene3D G3DSA:1.10.3720.10 87 292 1.0E-18 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_04055 cc4c6eb3895b25a87c52adf20da5cf9a 303 SUPERFAMILY SSF161098 92 278 3.27E-25 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23880 69c41058ce5386fbdf9984f99abbbe2a 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 69 1.7E-7 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4R43_23880 69c41058ce5386fbdf9984f99abbbe2a 301 SUPERFAMILY SSF161098 88 282 1.57E-23 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23880 69c41058ce5386fbdf9984f99abbbe2a 301 Gene3D G3DSA:1.10.3720.10 83 297 8.7E-22 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23880 69c41058ce5386fbdf9984f99abbbe2a 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 301 1.5E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_26910 89c0e733f748935e36c7d506b61a12c5 601 Pfam PF03972 MmgE/PrpD family 7 416 4.9E-90 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 A4R43_26910 89c0e733f748935e36c7d506b61a12c5 601 Gene3D G3DSA:3.30.1330.120 264 392 8.3E-85 T 14-10-2018 A4R43_26910 89c0e733f748935e36c7d506b61a12c5 601 Gene3D G3DSA:1.10.4100.10 25 408 8.3E-85 T 14-10-2018 A4R43_26910 89c0e733f748935e36c7d506b61a12c5 601 SUPERFAMILY SSF103378 471 598 4.05E-6 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 A4R43_26910 89c0e733f748935e36c7d506b61a12c5 601 SUPERFAMILY SSF103378 3 420 2.22E-87 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 A4R43_26910 89c0e733f748935e36c7d506b61a12c5 601 Gene3D G3DSA:1.10.4100.10 467 601 4.9E-9 T 14-10-2018 A4R43_10565 6e07524a3fad82d851f8a74ebd9ecc95 791 SUPERFAMILY SSF52540 494 762 1.46E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10565 6e07524a3fad82d851f8a74ebd9ecc95 791 Gene3D G3DSA:3.40.50.300 18 472 1.4E-155 T 14-10-2018 A4R43_10565 6e07524a3fad82d851f8a74ebd9ecc95 791 Gene3D G3DSA:1.20.1580.10 578 616 5.3E-102 T 14-10-2018 A4R43_10565 6e07524a3fad82d851f8a74ebd9ecc95 791 SUPERFAMILY SSF52540 17 454 3.28E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10565 6e07524a3fad82d851f8a74ebd9ecc95 791 Gene3D G3DSA:3.40.50.300 496 785 5.3E-102 T 14-10-2018 A4R43_10565 6e07524a3fad82d851f8a74ebd9ecc95 791 Gene3D G3DSA:1.20.1580.10 104 371 1.4E-155 T 14-10-2018 A4R43_10565 6e07524a3fad82d851f8a74ebd9ecc95 791 Gene3D G3DSA:1.10.8.280 184 293 1.4E-155 T 14-10-2018 A4R43_10565 6e07524a3fad82d851f8a74ebd9ecc95 791 Pfam PF00005 ABC transporter 502 709 5.1E-13 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_24315 345165507e1e88d1adf80a94b28d9ca6 216 Pfam PF13599 Pentapeptide repeats (9 copies) 47 104 5.6E-7 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_24315 345165507e1e88d1adf80a94b28d9ca6 216 Pfam PF13599 Pentapeptide repeats (9 copies) 107 173 2.2E-12 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_24315 345165507e1e88d1adf80a94b28d9ca6 216 SUPERFAMILY SSF141571 34 205 6.67E-32 T 14-10-2018 A4R43_24315 345165507e1e88d1adf80a94b28d9ca6 216 Gene3D G3DSA:2.160.20.100 12 214 2.8E-32 T 14-10-2018 A4R43_14355 5cfff9d1f27ea81fb71637f09421d4a8 277 Gene3D G3DSA:3.40.1280.10 117 276 6.0E-51 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_14355 5cfff9d1f27ea81fb71637f09421d4a8 277 Pfam PF00588 SpoU rRNA Methylase family 128 269 3.6E-34 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4R43_14355 5cfff9d1f27ea81fb71637f09421d4a8 277 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 44 112 3.2E-10 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A4R43_14355 5cfff9d1f27ea81fb71637f09421d4a8 277 Gene3D G3DSA:3.30.1330.30 17 114 1.6E-14 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_14355 5cfff9d1f27ea81fb71637f09421d4a8 277 SUPERFAMILY SSF55315 20 114 2.0E-17 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_14355 5cfff9d1f27ea81fb71637f09421d4a8 277 SUPERFAMILY SSF75217 105 271 7.19E-39 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_14355 5cfff9d1f27ea81fb71637f09421d4a8 277 SMART SM00967 44 117 7.2E-14 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A4R43_04275 342f11159d2d3e1fe82293f88682fdc0 111 SUPERFAMILY SSF46785 3 100 3.45E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04275 342f11159d2d3e1fe82293f88682fdc0 111 SMART SM00418 2 84 4.3E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_04275 342f11159d2d3e1fe82293f88682fdc0 111 Gene3D G3DSA:1.10.10.10 1 110 7.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04275 342f11159d2d3e1fe82293f88682fdc0 111 Pfam PF01022 Bacterial regulatory protein, arsR family 9 58 2.3E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_16020 30a32a215c071e2b6855d17eaa0e58bb 299 SUPERFAMILY SSF47203 172 297 1.15E-34 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16020 30a32a215c071e2b6855d17eaa0e58bb 299 Gene3D G3DSA:1.20.140.10 174 299 1.3E-32 T 14-10-2018 A4R43_16020 30a32a215c071e2b6855d17eaa0e58bb 299 SUPERFAMILY SSF56645 5 158 8.18E-15 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16020 30a32a215c071e2b6855d17eaa0e58bb 299 Gene3D G3DSA:2.40.110.10 85 173 2.9E-6 T 14-10-2018 A4R43_16020 30a32a215c071e2b6855d17eaa0e58bb 299 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 173 287 4.3E-22 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16020 30a32a215c071e2b6855d17eaa0e58bb 299 Gene3D G3DSA:1.10.540.10 2 84 7.5E-11 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16020 30a32a215c071e2b6855d17eaa0e58bb 299 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 78 1.1E-6 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 Pfam PF08264 Anticodon-binding domain of tRNA 393 471 1.2E-5 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 3 474 6.5E-127 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 Gene3D G3DSA:3.40.50.620 3 332 1.0E-121 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 Gene3D G3DSA:2.170.220.10 115 226 1.0E-121 T 14-10-2018 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 SUPERFAMILY SSF52374 2 349 4.5E-92 T 14-10-2018 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 SUPERFAMILY SSF47323 352 492 9.72E-28 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 PRINTS PR01041 Methionyl-tRNA synthetase signature 259 274 3.2E-28 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 PRINTS PR01041 Methionyl-tRNA synthetase signature 85 96 3.2E-28 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 PRINTS PR01041 Methionyl-tRNA synthetase signature 351 362 3.2E-28 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 3.2E-28 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 PRINTS PR01041 Methionyl-tRNA synthetase signature 37 51 3.2E-28 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 3.2E-28 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 Pfam PF09334 tRNA synthetases class I (M) 135 363 1.7E-60 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_02855 b8e90f6f16959cb2447aba08908b267c 492 Gene3D G3DSA:1.10.730.10 341 492 2.5E-34 T 14-10-2018 A4R43_26310 910daadcfac0cece59bd54f221f02c31 321 Gene3D G3DSA:3.10.180.10 67 214 2.2E-118 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_26310 910daadcfac0cece59bd54f221f02c31 321 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 270 8.2E-14 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_26310 910daadcfac0cece59bd54f221f02c31 321 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 127 6.6E-12 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_26310 910daadcfac0cece59bd54f221f02c31 321 SUPERFAMILY SSF54593 4 299 1.65E-49 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_26310 910daadcfac0cece59bd54f221f02c31 321 Gene3D G3DSA:3.10.180.10 7 308 2.2E-118 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_11830 ecabbd326d7c1627a9030c15452a17e5 264 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 11 230 6.8E-47 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 A4R43_06025 0dc1caf8d19e5779c48554c7437c0dce 158 SUPERFAMILY SSF47741 85 152 2.36E-31 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_06025 0dc1caf8d19e5779c48554c7437c0dce 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 54 3.0E-7 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_06025 0dc1caf8d19e5779c48554c7437c0dce 158 Pfam PF01799 [2Fe-2S] binding domain 74 147 8.0E-30 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_06025 0dc1caf8d19e5779c48554c7437c0dce 158 Gene3D G3DSA:1.10.150.120 77 158 3.2E-33 T 14-10-2018 A4R43_06025 0dc1caf8d19e5779c48554c7437c0dce 158 Gene3D G3DSA:3.10.20.30 1 76 1.2E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_06025 0dc1caf8d19e5779c48554c7437c0dce 158 SUPERFAMILY SSF54292 2 88 1.27E-20 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_06025 0dc1caf8d19e5779c48554c7437c0dce 158 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_02285 9e917500e5dcd3a2fb380822dff5ba1b 301 TIGRFAM TIGR01762 chlorin-enz: chlorinating enzyme 5 283 1.4E-87 T 14-10-2018 IPR010092 Chlorinating enzyme A4R43_02285 9e917500e5dcd3a2fb380822dff5ba1b 301 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 52 234 3.4E-26 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase A4R43_02285 9e917500e5dcd3a2fb380822dff5ba1b 301 Gene3D G3DSA:2.60.120.620 2 296 1.4E-98 T 14-10-2018 A4R43_02285 9e917500e5dcd3a2fb380822dff5ba1b 301 SUPERFAMILY SSF51197 5 293 9.16E-49 T 14-10-2018 A4R43_15855 0b6d52d6339e85718f6e9afa7e69ae4b 145 Gene3D G3DSA:3.30.530.20 3 144 2.5E-32 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_15855 0b6d52d6339e85718f6e9afa7e69ae4b 145 SUPERFAMILY SSF55961 1 143 2.85E-23 T 14-10-2018 A4R43_15855 0b6d52d6339e85718f6e9afa7e69ae4b 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 142 4.4E-15 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_07005 ac6830ec1f62c5f91664153bcf29a2ce 179 SUPERFAMILY SSF52499 2 157 3.53E-42 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_07005 ac6830ec1f62c5f91664153bcf29a2ce 179 Pfam PF00857 Isochorismatase family 4 138 6.6E-35 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4R43_07005 ac6830ec1f62c5f91664153bcf29a2ce 179 Gene3D G3DSA:3.40.50.850 1 165 2.3E-42 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_33340 cbf9a590fac31a7c3f771f6bfa664675 418 Gene3D G3DSA:3.40.50.2000 1 141 1.2E-9 T 14-10-2018 A4R43_33340 cbf9a590fac31a7c3f771f6bfa664675 418 Pfam PF13439 Glycosyltransferase Family 4 12 104 1.0E-8 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_33340 cbf9a590fac31a7c3f771f6bfa664675 418 Gene3D G3DSA:3.40.50.2000 142 348 1.8E-18 T 14-10-2018 A4R43_33340 cbf9a590fac31a7c3f771f6bfa664675 418 SUPERFAMILY SSF53756 4 361 1.41E-36 T 14-10-2018 A4R43_33340 cbf9a590fac31a7c3f771f6bfa664675 418 Pfam PF13692 Glycosyl transferases group 1 179 293 6.9E-10 T 14-10-2018 A4R43_06660 3d60940755a5c87cfef68a450e7505e0 600 Gene3D G3DSA:1.20.1560.10 8 345 4.8E-98 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_06660 3d60940755a5c87cfef68a450e7505e0 600 Pfam PF00664 ABC transporter transmembrane region 36 312 2.8E-59 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_06660 3d60940755a5c87cfef68a450e7505e0 600 Gene3D G3DSA:3.40.50.300 354 599 1.9E-90 T 14-10-2018 A4R43_06660 3d60940755a5c87cfef68a450e7505e0 600 SUPERFAMILY SSF52540 351 594 2.56E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06660 3d60940755a5c87cfef68a450e7505e0 600 SUPERFAMILY SSF90123 23 345 3.92E-85 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_06660 3d60940755a5c87cfef68a450e7505e0 600 Pfam PF00005 ABC transporter 375 523 1.7E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_06660 3d60940755a5c87cfef68a450e7505e0 600 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_06660 3d60940755a5c87cfef68a450e7505e0 600 SMART SM00382 383 569 4.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_37410 cc8d056d3ebb7dc537d7b4ac961655b3 64 SUPERFAMILY SSF54862 2 62 2.56E-14 T 14-10-2018 A4R43_37410 cc8d056d3ebb7dc537d7b4ac961655b3 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 6.4E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_37410 cc8d056d3ebb7dc537d7b4ac961655b3 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 6.4E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_37410 cc8d056d3ebb7dc537d7b4ac961655b3 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 6.4E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_37410 cc8d056d3ebb7dc537d7b4ac961655b3 64 Gene3D G3DSA:3.30.70.20 1 64 2.0E-21 T 14-10-2018 A4R43_37410 cc8d056d3ebb7dc537d7b4ac961655b3 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 6.9E-16 T 14-10-2018 A4R43_39645 bb0accac252c33ffac87827d0a6e4ff0 246 Pfam PF04452 RNA methyltransferase 18 239 8.7E-57 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A4R43_39645 bb0accac252c33ffac87827d0a6e4ff0 246 SUPERFAMILY SSF88697 4 57 2.32E-10 T 14-10-2018 IPR015947 PUA-like superfamily A4R43_39645 bb0accac252c33ffac87827d0a6e4ff0 246 PIRSF PIRSF015601 2 245 1.1E-48 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A4R43_39645 bb0accac252c33ffac87827d0a6e4ff0 246 Gene3D G3DSA:3.40.1280.10 74 246 5.1E-53 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_39645 bb0accac252c33ffac87827d0a6e4ff0 246 SUPERFAMILY SSF75217 76 245 8.37E-42 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_39645 bb0accac252c33ffac87827d0a6e4ff0 246 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 17 240 1.3E-33 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A4R43_39645 bb0accac252c33ffac87827d0a6e4ff0 246 Gene3D G3DSA:2.40.240.20 1 71 5.0E-20 T 14-10-2018 A4R43_04430 0b8b0f900998462461b19b1f2c2fc5fd 371 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 194 225 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4R43_04430 0b8b0f900998462461b19b1f2c2fc5fd 371 Gene3D G3DSA:3.20.20.120 124 357 2.3E-94 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_04430 0b8b0f900998462461b19b1f2c2fc5fd 371 SUPERFAMILY SSF54826 7 132 2.55E-24 T 14-10-2018 A4R43_04430 0b8b0f900998462461b19b1f2c2fc5fd 371 SMART SM00922 148 243 5.4E-20 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_04430 0b8b0f900998462461b19b1f2c2fc5fd 371 SUPERFAMILY SSF51604 119 370 5.11E-54 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_04430 0b8b0f900998462461b19b1f2c2fc5fd 371 Pfam PF13378 Enolase C-terminal domain-like 153 365 3.6E-47 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_04430 0b8b0f900998462461b19b1f2c2fc5fd 371 Gene3D G3DSA:3.30.390.10 27 364 2.3E-94 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_04430 0b8b0f900998462461b19b1f2c2fc5fd 371 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 26 131 4.8E-15 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_35935 47f9b3464427ab29b197c3923602a217 320 Gene3D G3DSA:1.10.10.10 1 64 3.9E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35935 47f9b3464427ab29b197c3923602a217 320 PIRSF PIRSF016838 67 318 2.8E-15 T 14-10-2018 IPR028349 Protein PafC A4R43_35935 47f9b3464427ab29b197c3923602a217 320 PIRSF PIRSF016838 1 57 2.5E-4 T 14-10-2018 IPR028349 Protein PafC A4R43_35935 47f9b3464427ab29b197c3923602a217 320 Pfam PF08279 HTH domain 5 60 8.7E-18 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_35935 47f9b3464427ab29b197c3923602a217 320 Pfam PF13280 WYL domain 141 315 1.7E-43 T 14-10-2018 IPR026881 WYL domain A4R43_35935 47f9b3464427ab29b197c3923602a217 320 SUPERFAMILY SSF46785 2 59 1.59E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 Pfam PF00226 DnaJ domain 10 72 4.3E-25 T 14-10-2018 IPR001623 DnaJ domain A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 Gene3D G3DSA:2.60.260.20 229 274 4.2E-13 T 14-10-2018 A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 Gene3D G3DSA:2.60.260.20 276 379 9.2E-30 T 14-10-2018 A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 SUPERFAMILY SSF49493 136 283 1.57E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 Gene3D G3DSA:1.10.287.110 8 118 2.4E-30 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 SMART SM00271 9 67 3.1E-26 T 14-10-2018 IPR001623 DnaJ domain A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 SUPERFAMILY SSF57938 156 231 7.06E-18 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 SUPERFAMILY SSF49493 281 364 5.23E-22 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 388 36.665 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 Pfam PF01556 DnaJ C terminal domain 142 354 5.4E-39 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 SUPERFAMILY SSF46565 9 114 3.53E-29 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 371 1.8E-120 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 Gene3D G3DSA:2.10.230.10 166 228 9.8E-18 T 14-10-2018 A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 PRINTS PR00625 DnaJ domain signature 47 67 1.1E-21 T 14-10-2018 IPR001623 DnaJ domain A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 PRINTS PR00625 DnaJ domain signature 67 86 1.1E-21 T 14-10-2018 IPR001623 DnaJ domain A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 PRINTS PR00625 DnaJ domain signature 30 45 1.1E-21 T 14-10-2018 IPR001623 DnaJ domain A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 PRINTS PR00625 DnaJ domain signature 12 30 1.1E-21 T 14-10-2018 IPR001623 DnaJ domain A4R43_31405 dec4fc60ac9630ae4ea661e273efb4a6 389 Pfam PF00684 DnaJ central domain 169 229 2.4E-10 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4R43_40255 dfefa54f42923aff6c741cefbec87b2a 298 Pfam PF00561 alpha/beta hydrolase fold 60 158 3.3E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_40255 dfefa54f42923aff6c741cefbec87b2a 298 SUPERFAMILY SSF53474 36 294 1.29E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40255 dfefa54f42923aff6c741cefbec87b2a 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 100 2.6E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_40255 dfefa54f42923aff6c741cefbec87b2a 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 129 142 2.6E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_40255 dfefa54f42923aff6c741cefbec87b2a 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 143 156 2.6E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_40255 dfefa54f42923aff6c741cefbec87b2a 298 Gene3D G3DSA:3.40.50.1820 30 295 3.2E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_26815 6fee61ac334b7b67e151330becc05013 206 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 20 203 41.021 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_26815 6fee61ac334b7b67e151330becc05013 206 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 130 140 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_26815 6fee61ac334b7b67e151330becc05013 206 SUPERFAMILY SSF55620 16 203 8.89E-75 T 14-10-2018 A4R43_26815 6fee61ac334b7b67e151330becc05013 206 Pfam PF01227 GTP cyclohydrolase I 25 202 2.3E-74 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_26815 6fee61ac334b7b67e151330becc05013 206 Gene3D G3DSA:3.30.1130.10 70 204 1.0E-57 T 14-10-2018 A4R43_26815 6fee61ac334b7b67e151330becc05013 206 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 25 203 5.0E-71 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_26815 6fee61ac334b7b67e151330becc05013 206 Gene3D G3DSA:1.10.286.10 7 68 1.3E-19 T 14-10-2018 A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 SMART SM00345 9 68 2.2E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 SUPERFAMILY SSF46785 5 85 1.86E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 1.0E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 152 301 2.8E-15 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 Gene3D G3DSA:1.10.357.10 148 306 3.2E-36 T 14-10-2018 A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 Pfam PF00440 Bacterial regulatory proteins, tetR family 98 139 4.8E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 SUPERFAMILY SSF48498 158 305 2.31E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 SUPERFAMILY SSF46689 86 149 1.28E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 Gene3D G3DSA:1.10.10.10 5 76 1.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35175 217c77ab7fc118b8d4f71750a7665c24 310 Gene3D G3DSA:1.10.10.60 86 147 6.6E-25 T 14-10-2018 A4R43_20355 4d5edd5c675833a86f691bf52187d9fc 419 SUPERFAMILY SSF56176 6 189 5.14E-42 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_20355 4d5edd5c675833a86f691bf52187d9fc 419 Gene3D G3DSA:3.40.462.20 189 393 1.0E-88 T 14-10-2018 A4R43_20355 4d5edd5c675833a86f691bf52187d9fc 419 Pfam PF01565 FAD binding domain 27 157 9.5E-24 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_20355 4d5edd5c675833a86f691bf52187d9fc 419 Gene3D G3DSA:3.30.43.10 2 74 5.4E-13 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_20355 4d5edd5c675833a86f691bf52187d9fc 419 Gene3D G3DSA:3.30.465.10 89 417 1.0E-88 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 SMART SM00829 14 362 0.0077 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 Gene3D G3DSA:3.40.50.720 167 307 6.9E-119 T 14-10-2018 A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 147 8.9E-26 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 Gene3D G3DSA:3.90.180.10 9 361 6.9E-119 T 14-10-2018 A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 SUPERFAMILY SSF50129 313 364 7.06E-9 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 364 1.0E-206 T 14-10-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase MetaCyc: PWY-7908 A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 Pfam PF00107 Zinc-binding dehydrogenase 190 319 3.7E-26 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 SUPERFAMILY SSF51735 155 329 1.51E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_25480 14905a6df5e3e0a1a2961ad40cd58479 364 SUPERFAMILY SSF50129 4 186 1.07E-53 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 Gene3D G3DSA:1.10.10.10 1 86 4.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 Gene3D G3DSA:3.40.190.290 91 293 7.2E-46 T 14-10-2018 A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 Pfam PF03466 LysR substrate binding domain 95 287 1.8E-42 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 SUPERFAMILY SSF46785 1 85 1.95E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 8.7E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_19760 82e9f66f6147dea0736389cbfa646395 305 SUPERFAMILY SSF53850 102 292 2.17E-36 T 14-10-2018 A4R43_12240 11d9e13540c88518e11ec84548d4ecde 650 SUPERFAMILY SSF49265 463 549 1.9E-17 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_12240 11d9e13540c88518e11ec84548d4ecde 650 Pfam PF00041 Fibronectin type III domain 475 546 4.1E-13 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_12240 11d9e13540c88518e11ec84548d4ecde 650 SMART SM00060 467 545 1.1E-9 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_12240 11d9e13540c88518e11ec84548d4ecde 650 SUPERFAMILY SSF82171 167 368 1.1E-7 T 14-10-2018 A4R43_12240 11d9e13540c88518e11ec84548d4ecde 650 Gene3D G3DSA:2.60.40.10 462 555 1.4E-17 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_26500 650366b225ab69b45e219b9d6ff8141f 286 Pfam PF03466 LysR substrate binding domain 85 283 2.2E-39 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_26500 650366b225ab69b45e219b9d6ff8141f 286 SUPERFAMILY SSF53850 85 285 6.11E-40 T 14-10-2018 A4R43_26500 650366b225ab69b45e219b9d6ff8141f 286 Gene3D G3DSA:1.10.10.10 1 89 1.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26500 650366b225ab69b45e219b9d6ff8141f 286 Gene3D G3DSA:3.40.190.290 90 286 1.8E-31 T 14-10-2018 A4R43_26500 650366b225ab69b45e219b9d6ff8141f 286 SUPERFAMILY SSF46785 1 109 1.67E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26500 650366b225ab69b45e219b9d6ff8141f 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.9E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17745 529a281f4e737eda7cd6a2fe1093646e 267 Pfam PF09339 IclR helix-turn-helix domain 20 66 6.0E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_17745 529a281f4e737eda7cd6a2fe1093646e 267 SUPERFAMILY SSF55781 73 260 1.83E-40 T 14-10-2018 A4R43_17745 529a281f4e737eda7cd6a2fe1093646e 267 SUPERFAMILY SSF46785 20 84 2.57E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_17745 529a281f4e737eda7cd6a2fe1093646e 267 Gene3D G3DSA:1.10.10.10 11 84 3.4E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17745 529a281f4e737eda7cd6a2fe1093646e 267 SMART SM00346 17 105 1.4E-4 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_17745 529a281f4e737eda7cd6a2fe1093646e 267 Gene3D G3DSA:3.30.450.40 92 265 1.6E-44 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_17745 529a281f4e737eda7cd6a2fe1093646e 267 Pfam PF01614 Bacterial transcriptional regulator 138 256 1.2E-26 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_21625 f0b31cf8a1643cbeeb2ddde30aa8b60e 134 SMART SM00347 12 113 8.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_21625 f0b31cf8a1643cbeeb2ddde30aa8b60e 134 SUPERFAMILY SSF46785 5 128 4.68E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_21625 f0b31cf8a1643cbeeb2ddde30aa8b60e 134 Pfam PF12802 MarR family 17 72 3.6E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_21625 f0b31cf8a1643cbeeb2ddde30aa8b60e 134 Gene3D G3DSA:1.10.10.10 1 132 2.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09525 c586a8ee2fed821ba73c9687dd21b878 271 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_09525 c586a8ee2fed821ba73c9687dd21b878 271 SUPERFAMILY SSF52540 5 251 7.14E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09525 c586a8ee2fed821ba73c9687dd21b878 271 SMART SM00382 36 230 2.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_09525 c586a8ee2fed821ba73c9687dd21b878 271 Gene3D G3DSA:3.40.50.300 3 268 8.1E-81 T 14-10-2018 A4R43_09525 c586a8ee2fed821ba73c9687dd21b878 271 Pfam PF00005 ABC transporter 28 180 4.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_10130 25588002933ed453942ee35bca09133d 332 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 311 4.3E-110 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 A4R43_10130 25588002933ed453942ee35bca09133d 332 Pfam PF03741 Integral membrane protein TerC family 70 273 6.9E-51 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A4R43_26385 8c56e177165bb02ade2b01424e3bc6f1 94 Pfam PF06243 Phenylacetic acid degradation B 4 90 3.9E-39 T 14-10-2018 IPR009359 Phenylacetic acid degradation B A4R43_26385 8c56e177165bb02ade2b01424e3bc6f1 94 PIRSF PIRSF030200 1 94 2.9E-44 T 14-10-2018 IPR009359 Phenylacetic acid degradation B A4R43_26385 8c56e177165bb02ade2b01424e3bc6f1 94 Gene3D G3DSA:3.10.20.520 1 64 2.0E-31 T 14-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B A4R43_26385 8c56e177165bb02ade2b01424e3bc6f1 94 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 5 94 2.2E-47 T 14-10-2018 IPR009359 Phenylacetic acid degradation B A4R43_37540 094abbf48b5ba6dc414efafd3e1ea2e1 269 Pfam PF01061 ABC-2 type transporter 18 224 3.2E-25 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_37540 094abbf48b5ba6dc414efafd3e1ea2e1 269 PIRSF PIRSF006648 1 269 7.5E-70 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_34485 56e2583e64f4163d8a5816303c0e7bd9 205 SUPERFAMILY SSF53328 8 202 6.28E-58 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_34485 56e2583e64f4163d8a5816303c0e7bd9 205 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 7 193 5.1E-67 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A4R43_34485 56e2583e64f4163d8a5816303c0e7bd9 205 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 139 162 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_34485 56e2583e64f4163d8a5816303c0e7bd9 205 Gene3D G3DSA:3.40.50.170 2 205 3.1E-78 T 14-10-2018 A4R43_34485 56e2583e64f4163d8a5816303c0e7bd9 205 Pfam PF00551 Formyl transferase 8 187 2.6E-50 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_34485 56e2583e64f4163d8a5816303c0e7bd9 205 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 8 193 28.693 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A4R43_15615 4bb0ce1532bd24202fe908f130d82180 140 SUPERFAMILY SSF49764 4 130 9.42E-30 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_15615 4bb0ce1532bd24202fe908f130d82180 140 Gene3D G3DSA:2.60.40.790 1 130 2.2E-27 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_15615 4bb0ce1532bd24202fe908f130d82180 140 Pfam PF00011 Hsp20/alpha crystallin family 34 129 1.0E-18 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4R43_37175 fa2cc56a975437dc00d2b9cb88c89b7b 370 Pfam PF01494 FAD binding domain 2 315 1.1E-18 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_37175 fa2cc56a975437dc00d2b9cb88c89b7b 370 Gene3D G3DSA:3.50.50.60 1 338 1.1E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37175 fa2cc56a975437dc00d2b9cb88c89b7b 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 5.5E-11 T 14-10-2018 A4R43_37175 fa2cc56a975437dc00d2b9cb88c89b7b 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 5.5E-11 T 14-10-2018 A4R43_37175 fa2cc56a975437dc00d2b9cb88c89b7b 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 5.5E-11 T 14-10-2018 A4R43_37175 fa2cc56a975437dc00d2b9cb88c89b7b 370 Gene3D G3DSA:3.30.9.30 32 343 1.1E-82 T 14-10-2018 A4R43_37175 fa2cc56a975437dc00d2b9cb88c89b7b 370 SUPERFAMILY SSF51905 1 360 2.02E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23925 01e9871a89b47e70d2b03745a00f4e60 153 Gene3D G3DSA:3.30.720.110 82 150 8.9E-19 T 14-10-2018 A4R43_23925 01e9871a89b47e70d2b03745a00f4e60 153 SUPERFAMILY SSF54593 15 135 2.55E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_23925 01e9871a89b47e70d2b03745a00f4e60 153 Gene3D G3DSA:3.30.720.120 13 77 3.8E-12 T 14-10-2018 A4R43_26995 026145b51ca0aa06665b50023c488c89 804 Pfam PF00270 DEAD/DEAH box helicase 67 232 4.5E-20 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_26995 026145b51ca0aa06665b50023c488c89 804 Pfam PF09369 Domain of unknown function (DUF1998) 675 754 4.1E-17 T 14-10-2018 IPR018973 DEAD/DEAH-box helicase, putative A4R43_26995 026145b51ca0aa06665b50023c488c89 804 Gene3D G3DSA:3.40.50.300 48 246 6.8E-38 T 14-10-2018 A4R43_26995 026145b51ca0aa06665b50023c488c89 804 SMART SM00490 321 402 5.2E-14 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_26995 026145b51ca0aa06665b50023c488c89 804 Gene3D G3DSA:3.40.50.300 281 425 4.2E-17 T 14-10-2018 A4R43_26995 026145b51ca0aa06665b50023c488c89 804 SUPERFAMILY SSF52540 74 412 4.91E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26995 026145b51ca0aa06665b50023c488c89 804 SMART SM00487 60 262 6.7E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_26995 026145b51ca0aa06665b50023c488c89 804 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 28 781 0.0 T 14-10-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria A4R43_26995 026145b51ca0aa06665b50023c488c89 804 Pfam PF00271 Helicase conserved C-terminal domain 296 402 1.2E-8 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_24770 f23776f08f34a6c874741d73b5361b64 527 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 110 2.4E-7 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24770 f23776f08f34a6c874741d73b5361b64 527 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 2.0E-18 T 14-10-2018 A4R43_24770 f23776f08f34a6c874741d73b5361b64 527 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 2.0E-18 T 14-10-2018 A4R43_24770 f23776f08f34a6c874741d73b5361b64 527 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 2.0E-18 T 14-10-2018 A4R43_24770 f23776f08f34a6c874741d73b5361b64 527 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 302 314 2.0E-18 T 14-10-2018 A4R43_24770 f23776f08f34a6c874741d73b5361b64 527 Pfam PF00361 Proton-conducting membrane transporter 127 347 5.4E-37 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_00670 ad74c3aa76e6907c852c88fbc646a0b2 320 SUPERFAMILY SSF52540 8 230 4.1E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_00670 ad74c3aa76e6907c852c88fbc646a0b2 320 Pfam PF00005 ABC transporter 25 168 1.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_00670 ad74c3aa76e6907c852c88fbc646a0b2 320 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 309 1.5E-98 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_00670 ad74c3aa76e6907c852c88fbc646a0b2 320 SMART SM00382 34 217 5.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_00670 ad74c3aa76e6907c852c88fbc646a0b2 320 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_00670 ad74c3aa76e6907c852c88fbc646a0b2 320 Gene3D G3DSA:3.40.50.300 2 234 2.9E-65 T 14-10-2018 A4R43_00670 ad74c3aa76e6907c852c88fbc646a0b2 320 Pfam PF13732 Domain of unknown function (DUF4162) 222 307 8.5E-7 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 A4R43_19330 044bfdf98928476977f967e124afccb5 101 Gene3D G3DSA:3.40.50.2300 2 95 5.5E-24 T 14-10-2018 A4R43_19330 044bfdf98928476977f967e124afccb5 101 SUPERFAMILY SSF52794 9 90 7.59E-16 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A4R43_19330 044bfdf98928476977f967e124afccb5 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 11 83 1.1E-9 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A4R43_27170 c4017d2a4ca90cff2fee420520af4226 224 SUPERFAMILY SSF46785 145 223 3.33E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_27170 c4017d2a4ca90cff2fee420520af4226 224 SMART SM00419 167 215 8.6E-14 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4R43_27170 c4017d2a4ca90cff2fee420520af4226 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 3.3E-19 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4R43_27170 c4017d2a4ca90cff2fee420520af4226 224 SMART SM00100 10 128 1.4E-24 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_27170 c4017d2a4ca90cff2fee420520af4226 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 1.2E-23 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_27170 c4017d2a4ca90cff2fee420520af4226 224 SUPERFAMILY SSF51206 4 142 3.14E-36 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like A4R43_27170 c4017d2a4ca90cff2fee420520af4226 224 Gene3D G3DSA:2.60.120.10 1 146 2.2E-45 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_27170 c4017d2a4ca90cff2fee420520af4226 224 Gene3D G3DSA:1.10.10.10 147 224 2.6E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28170 a58097dc0ab7b0a1c97287c24fa5c1f3 408 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 18 392 7.4E-107 T 14-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A4R43_28170 a58097dc0ab7b0a1c97287c24fa5c1f3 408 SUPERFAMILY SSF51971 18 389 1.12E-45 T 14-10-2018 A4R43_28170 a58097dc0ab7b0a1c97287c24fa5c1f3 408 Pfam PF13450 NAD(P)-binding Rossmann-like domain 22 91 1.2E-17 T 14-10-2018 A4R43_28170 a58097dc0ab7b0a1c97287c24fa5c1f3 408 SUPERFAMILY SSF54373 267 338 2.75E-22 T 14-10-2018 A4R43_28170 a58097dc0ab7b0a1c97287c24fa5c1f3 408 Gene3D G3DSA:3.40.50.720 291 401 1.3E-19 T 14-10-2018 A4R43_28170 a58097dc0ab7b0a1c97287c24fa5c1f3 408 Gene3D G3DSA:3.40.50.720 15 110 6.8E-34 T 14-10-2018 A4R43_28170 a58097dc0ab7b0a1c97287c24fa5c1f3 408 Gene3D G3DSA:3.40.50.720 171 279 1.8E-25 T 14-10-2018 A4R43_28170 a58097dc0ab7b0a1c97287c24fa5c1f3 408 Pfam PF03275 UDP-galactopyranose mutase 166 374 2.5E-79 T 14-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A4R43_30790 e7062c29feed6f5632beb092145e660a 258 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 162 169 - T 14-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A4R43_30790 e7062c29feed6f5632beb092145e660a 258 Gene3D G3DSA:3.20.20.150 1 257 1.8E-53 T 14-10-2018 A4R43_30790 e7062c29feed6f5632beb092145e660a 258 Pfam PF01261 Xylose isomerase-like TIM barrel 15 213 2.2E-21 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_30790 e7062c29feed6f5632beb092145e660a 258 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 56 64 - T 14-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A4R43_30790 e7062c29feed6f5632beb092145e660a 258 SMART SM00518 2 256 3.9E-42 T 14-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A4R43_30790 e7062c29feed6f5632beb092145e660a 258 SUPERFAMILY SSF51658 1 251 4.58E-51 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_04105 4ce77a7c0d577bcb1510b1ef559ee5e4 325 Gene3D G3DSA:3.40.50.1980 147 325 1.5E-34 T 14-10-2018 A4R43_04105 4ce77a7c0d577bcb1510b1ef559ee5e4 325 Gene3D G3DSA:3.40.50.1980 34 143 1.9E-15 T 14-10-2018 A4R43_04105 4ce77a7c0d577bcb1510b1ef559ee5e4 325 Pfam PF01497 Periplasmic binding protein 59 302 3.8E-18 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_04105 4ce77a7c0d577bcb1510b1ef559ee5e4 325 SUPERFAMILY SSF53807 40 318 3.26E-41 T 14-10-2018 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Pfam PF01381 Helix-turn-helix 7 55 3.9E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Pfam PF00486 Transcriptional regulatory protein, C terminal 77 156 3.2E-12 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00382 346 484 1.6E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Pfam PF13424 Tetratricopeptide repeat 762 829 1.4E-13 T 14-10-2018 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Pfam PF13424 Tetratricopeptide repeat 841 907 2.2E-9 T 14-10-2018 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Pfam PF13424 Tetratricopeptide repeat 923 989 1.7E-12 T 14-10-2018 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Gene3D G3DSA:1.25.40.10 729 907 2.9E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Gene3D G3DSA:1.25.40.10 160 325 1.9E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SUPERFAMILY SSF47413 3 55 3.94E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Gene3D G3DSA:1.10.10.10 56 158 4.8E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SUPERFAMILY SSF52540 317 582 2.09E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Gene3D G3DSA:1.25.40.10 908 1078 3.5E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Pfam PF00931 NB-ARC domain 336 576 4.1E-7 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SUPERFAMILY SSF46894 62 156 1.39E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Gene3D G3DSA:1.10.260.40 2 55 3.6E-10 T 14-10-2018 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SUPERFAMILY SSF48452 161 318 7.32E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SUPERFAMILY SSF48452 758 912 1.2E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SUPERFAMILY SSF48452 919 1062 8.8E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00028 917 950 1.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00028 837 870 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00028 957 990 0.3 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00028 877 910 13.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00028 797 830 2.8E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00028 757 790 9.6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00028 997 1030 14.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 Pfam PF03704 Bacterial transcriptional activator domain 163 304 2.2E-29 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 PRINTS PR00364 Disease resistance protein signature 514 528 3.9E-5 T 14-10-2018 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 PRINTS PR00364 Disease resistance protein signature 349 364 3.9E-5 T 14-10-2018 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 PRINTS PR00364 Disease resistance protein signature 427 441 3.9E-5 T 14-10-2018 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00862 76 156 5.4E-14 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM01043 163 304 3.4E-36 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_20815 138ce53b2ce3f4d42eafbf1a928b59fc 1080 SMART SM00530 6 61 9.3E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_24540 36ef2f5cc1525d4059b36423301885a7 687 SUPERFAMILY SSF56349 332 522 7.36E-7 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_21825 4448216549f4a813fbc1ae9f80ad723a 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 257 272 2.7E-17 T 14-10-2018 A4R43_21825 4448216549f4a813fbc1ae9f80ad723a 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 133 148 2.7E-17 T 14-10-2018 A4R43_21825 4448216549f4a813fbc1ae9f80ad723a 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.7E-17 T 14-10-2018 A4R43_21825 4448216549f4a813fbc1ae9f80ad723a 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 288 2.7E-17 T 14-10-2018 A4R43_21825 4448216549f4a813fbc1ae9f80ad723a 376 Gene3D G3DSA:3.50.50.60 5 344 9.7E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21825 4448216549f4a813fbc1ae9f80ad723a 376 SUPERFAMILY SSF51905 6 348 7.59E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21825 4448216549f4a813fbc1ae9f80ad723a 376 Pfam PF01494 FAD binding domain 127 319 4.0E-15 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_21825 4448216549f4a813fbc1ae9f80ad723a 376 Pfam PF01494 FAD binding domain 5 67 6.4E-5 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Gene3D G3DSA:3.40.50.300 354 553 6.3E-71 T 14-10-2018 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Gene3D G3DSA:1.10.1780.10 3 156 1.1E-37 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 684 702 5.7E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 655 673 5.7E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 610 628 5.7E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 717 731 5.7E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 SUPERFAMILY SSF81923 5 161 1.44E-41 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 70 2.2E-15 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 98 151 1.7E-10 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Gene3D G3DSA:3.40.50.300 163 353 1.5E-71 T 14-10-2018 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 866 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 SUPERFAMILY SSF52540 165 554 2.96E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Pfam PF07724 AAA domain (Cdc48 subfamily) 605 771 3.5E-55 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 SMART SM00382 204 349 1.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 SMART SM00382 606 759 1.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 SUPERFAMILY SSF52540 555 862 1.15E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 640 658 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 SMART SM01086 777 866 2.8E-34 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 330 2.1E-11 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 777 857 1.4E-23 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Gene3D G3DSA:3.40.50.300 559 775 8.7E-88 T 14-10-2018 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 300 312 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4R43_29455 14792f9d81bdf0e8027de0fb0f084512 889 Gene3D G3DSA:1.10.8.60 777 871 1.3E-25 T 14-10-2018 A4R43_02555 d41a5d61d2c84a80d3fea113544c15b5 518 Pfam PF00561 alpha/beta hydrolase fold 102 279 7.3E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02555 d41a5d61d2c84a80d3fea113544c15b5 518 SUPERFAMILY SSF53474 98 495 9.06E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02555 d41a5d61d2c84a80d3fea113544c15b5 518 Pfam PF08386 TAP-like protein 415 506 2.0E-20 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_05565 b417467c03d2b3371b76419735c0cfa0 90 Pfam PF11239 Protein of unknown function (DUF3040) 1 78 5.9E-14 T 14-10-2018 IPR021401 Protein of unknown function DUF3040 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 3.9E-17 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 6.5E-18 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Gene3D G3DSA:3.40.50.300 472 718 3.0E-95 T 14-10-2018 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Pfam PF02151 UvrB/uvrC motif 422 454 6.7E-8 T 14-10-2018 IPR001943 UVR domain GO:0005515 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Gene3D G3DSA:1.10.8.60 720 819 1.4E-27 T 14-10-2018 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 SUPERFAMILY SSF81923 3 144 2.55E-32 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 SUPERFAMILY SSF52540 168 485 3.62E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Gene3D G3DSA:3.40.50.300 349 469 4.5E-38 T 14-10-2018 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 SMART SM00382 542 721 3.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 SMART SM00382 205 349 3.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Gene3D G3DSA:1.10.1780.10 1 148 5.4E-64 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 SUPERFAMILY SSF52540 491 804 4.65E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Gene3D G3DSA:3.40.50.300 159 348 1.8E-70 T 14-10-2018 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 1.3E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 1.3E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 667 1.3E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 1.3E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 325 2.9E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 720 799 5.9E-25 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 714 2.5E-50 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 300 312 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4R43_26740 7433c18b76f046378581a72a7c6b98ac 852 SMART SM01086 720 811 3.3E-34 T 14-10-2018 IPR019489 Clp ATPase, C-terminal A4R43_26585 d961b691208b7398fab950871da811b9 156 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 154 29.621 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4R43_26585 d961b691208b7398fab950871da811b9 156 SUPERFAMILY SSF69765 2 153 2.09E-49 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4R43_26585 d961b691208b7398fab950871da811b9 156 Pfam PF02542 YgbB family 3 152 2.1E-46 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4R43_26585 d961b691208b7398fab950871da811b9 156 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 152 4.0E-44 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4R43_26585 d961b691208b7398fab950871da811b9 156 Gene3D G3DSA:3.30.1330.50 1 155 1.4E-56 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4R43_26585 d961b691208b7398fab950871da811b9 156 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4R43_06375 233b9e84f519e5163723a160fbf35ee7 348 Gene3D G3DSA:1.10.260.40 11 73 9.9E-16 T 14-10-2018 A4R43_06375 233b9e84f519e5163723a160fbf35ee7 348 Gene3D G3DSA:3.40.50.2300 174 303 3.9E-73 T 14-10-2018 A4R43_06375 233b9e84f519e5163723a160fbf35ee7 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 62 1.6E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_06375 233b9e84f519e5163723a160fbf35ee7 348 SMART SM00354 17 84 5.1E-9 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_06375 233b9e84f519e5163723a160fbf35ee7 348 Pfam PF13377 Periplasmic binding protein-like domain 182 343 5.5E-42 T 14-10-2018 A4R43_06375 233b9e84f519e5163723a160fbf35ee7 348 Gene3D G3DSA:3.40.50.2300 86 335 3.9E-73 T 14-10-2018 A4R43_06375 233b9e84f519e5163723a160fbf35ee7 348 SUPERFAMILY SSF53822 76 346 1.4E-78 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_06375 233b9e84f519e5163723a160fbf35ee7 348 SUPERFAMILY SSF47413 17 64 1.69E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_37420 67524828f472e5a5aac414512dfca78c 475 SUPERFAMILY SSF50952 107 405 2.35E-9 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_37420 67524828f472e5a5aac414512dfca78c 475 Pfam PF07995 Glucose / Sorbosone dehydrogenase 118 408 4.9E-19 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_37420 67524828f472e5a5aac414512dfca78c 475 Gene3D G3DSA:2.120.10.30 69 471 4.9E-46 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_27525 b43205d462366845f310fd35ce28a45a 255 SUPERFAMILY SSF50494 8 255 1.87E-56 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_27525 b43205d462366845f310fd35ce28a45a 255 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 70 75 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4R43_27525 b43205d462366845f310fd35ce28a45a 255 SMART SM00020 34 250 1.2E-49 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_27525 b43205d462366845f310fd35ce28a45a 255 Pfam PF00089 Trypsin 35 250 2.4E-44 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_27525 b43205d462366845f310fd35ce28a45a 255 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 115 129 9.8E-15 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_27525 b43205d462366845f310fd35ce28a45a 255 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 60 75 9.8E-15 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_27525 b43205d462366845f310fd35ce28a45a 255 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 198 210 9.8E-15 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_27525 b43205d462366845f310fd35ce28a45a 255 Gene3D G3DSA:2.40.10.10 27 254 6.7E-50 T 14-10-2018 A4R43_25565 d6aa9a358a2956f5c88083c9dd3427ce 301 Gene3D G3DSA:2.70.98.10 10 301 2.0E-72 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_25565 d6aa9a358a2956f5c88083c9dd3427ce 301 SUPERFAMILY SSF74650 8 300 1.0E-55 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A4R43_25565 d6aa9a358a2956f5c88083c9dd3427ce 301 Pfam PF01263 Aldose 1-epimerase 9 295 1.1E-40 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 Pfam PF00298 Ribosomal protein L11, RNA binding domain 76 143 2.2E-21 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 11 145 22.848 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 Gene3D G3DSA:3.30.1550.10 10 77 9.5E-14 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 Gene3D G3DSA:1.10.10.2720 78 145 9.7E-23 T 14-10-2018 A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 ProSitePatterns PS00359 Ribosomal protein L11 signature. 130 145 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 SUPERFAMILY SSF46906 73 144 5.1E-20 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 SMART SM00649 15 144 1.3E-45 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 Pfam PF03946 Ribosomal protein L11, N-terminal domain 17 71 1.5E-12 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal A4R43_26915 4df3cfd0ecd5aa11b2cb4a205cc1b229 145 SUPERFAMILY SSF54747 7 89 2.35E-14 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A4R43_16100 d0d93d9dd67d361c652dd8bfaf911c8f 345 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 100 2.9E-13 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_16100 d0d93d9dd67d361c652dd8bfaf911c8f 345 SUPERFAMILY SSF47203 216 341 7.25E-23 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16100 d0d93d9dd67d361c652dd8bfaf911c8f 345 SUPERFAMILY SSF56645 15 201 9.69E-33 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16100 d0d93d9dd67d361c652dd8bfaf911c8f 345 Gene3D G3DSA:1.10.540.10 3 103 1.5E-18 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16100 d0d93d9dd67d361c652dd8bfaf911c8f 345 Gene3D G3DSA:1.20.140.10 211 345 4.1E-23 T 14-10-2018 A4R43_16100 d0d93d9dd67d361c652dd8bfaf911c8f 345 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 217 325 1.8E-15 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16100 d0d93d9dd67d361c652dd8bfaf911c8f 345 Gene3D G3DSA:2.40.110.10 104 207 1.2E-19 T 14-10-2018 A4R43_33025 cfe7245ea147dee2aa681e4b70ca9eff 371 Gene3D G3DSA:3.30.300.310 271 370 3.5E-26 T 14-10-2018 A4R43_33025 cfe7245ea147dee2aa681e4b70ca9eff 371 Gene3D G3DSA:3.40.50.12780 33 268 2.4E-52 T 14-10-2018 A4R43_33025 cfe7245ea147dee2aa681e4b70ca9eff 371 SUPERFAMILY SSF56801 24 370 1.01E-80 T 14-10-2018 A4R43_33025 cfe7245ea147dee2aa681e4b70ca9eff 371 Pfam PF13193 AMP-binding enzyme C-terminal domain 285 358 3.4E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_33025 cfe7245ea147dee2aa681e4b70ca9eff 371 Pfam PF00501 AMP-binding enzyme 37 275 7.7E-38 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_33025 cfe7245ea147dee2aa681e4b70ca9eff 371 ProSitePatterns PS00455 Putative AMP-binding domain signature. 49 60 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_32010 c1c1ce36e5fde7a447a8b2253fc9ae22 62 Pfam PF11273 Protein of unknown function (DUF3073) 2 61 2.6E-23 T 14-10-2018 IPR021426 Protein of unknown function DUF3073 A4R43_08755 50b02dbb1684caefef2a61479de5116f 131 SUPERFAMILY SSF55811 8 112 4.2E-19 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_08755 50b02dbb1684caefef2a61479de5116f 131 Pfam PF00293 NUDIX domain 12 109 1.2E-10 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_08755 50b02dbb1684caefef2a61479de5116f 131 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_08755 50b02dbb1684caefef2a61479de5116f 131 Gene3D G3DSA:3.90.79.10 4 128 4.8E-20 T 14-10-2018 A4R43_31860 7ea14656d1047f4386625e33f8f8cec0 531 SUPERFAMILY SSF52540 369 521 2.9E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31860 7ea14656d1047f4386625e33f8f8cec0 531 Pfam PF00664 ABC transporter transmembrane region 40 293 2.6E-25 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_31860 7ea14656d1047f4386625e33f8f8cec0 531 Gene3D G3DSA:1.20.1560.10 3 326 1.6E-45 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_31860 7ea14656d1047f4386625e33f8f8cec0 531 SUPERFAMILY SSF90123 11 330 1.57E-50 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_31860 7ea14656d1047f4386625e33f8f8cec0 531 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_31860 7ea14656d1047f4386625e33f8f8cec0 531 Gene3D G3DSA:3.40.50.300 351 528 1.5E-35 T 14-10-2018 A4R43_31860 7ea14656d1047f4386625e33f8f8cec0 531 Pfam PF00005 ABC transporter 375 483 2.9E-11 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 PIRSF PIRSF036389 1 685 7.0E-179 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 SUPERFAMILY SSF56003 4 230 5.58E-31 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 24 8.8E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 Gene3D G3DSA:3.30.365.10 528 684 1.6E-24 T 14-10-2018 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 SUPERFAMILY SSF56003 305 683 4.71E-83 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 Gene3D G3DSA:3.30.365.10 33 170 1.2E-20 T 14-10-2018 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 Gene3D G3DSA:3.90.1170.50 171 279 2.7E-11 T 14-10-2018 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 Gene3D G3DSA:3.30.365.10 311 519 3.9E-41 T 14-10-2018 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 Gene3D G3DSA:3.30.365.10 321 413 3.9E-41 T 14-10-2018 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 310 521 4.0E-21 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 39 165 1.9E-13 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 563 635 6.2E-8 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_10040 1be33846178e1a847a3fc7add8cb5348 685 SMART SM01008 198 282 3.2E-13 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_26355 7708f9d19385d673f9613a0c30b99f47 305 SUPERFAMILY SSF53067 5 298 1.44E-54 T 14-10-2018 A4R43_26355 7708f9d19385d673f9613a0c30b99f47 305 Gene3D G3DSA:3.30.420.40 126 280 2.5E-76 T 14-10-2018 A4R43_26355 7708f9d19385d673f9613a0c30b99f47 305 Pfam PF00480 ROK family 6 295 8.9E-53 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_26355 7708f9d19385d673f9613a0c30b99f47 305 Gene3D G3DSA:3.30.420.40 6 292 2.5E-76 T 14-10-2018 A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 770 56.051 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 PIRSF PIRSF006288 3 581 2.0E-132 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 PIRSF PIRSF006288 565 770 1.2E-25 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 SUPERFAMILY SSF81593 178 277 1.96E-5 T 14-10-2018 A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 Pfam PF01966 HD domain 407 525 5.0E-10 T 14-10-2018 IPR006674 HD domain A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 SMART SM00471 411 540 3.1E-6 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 SUPERFAMILY SSF109604 379 539 6.91E-14 T 14-10-2018 A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 SUPERFAMILY SSF81301 21 147 2.24E-14 T 14-10-2018 A4R43_18500 77c6e7949c3fad2ca43da5615c2212cc 770 Gene3D G3DSA:1.10.3210.10 404 532 9.0E-9 T 14-10-2018 A4R43_39890 ef81a3e0cb1454202f17ca23d0065f94 381 Gene3D G3DSA:2.60.120.200 160 380 1.7E-87 T 14-10-2018 A4R43_39890 ef81a3e0cb1454202f17ca23d0065f94 381 SUPERFAMILY SSF49785 35 154 5.67E-25 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_39890 ef81a3e0cb1454202f17ca23d0065f94 381 Gene3D G3DSA:2.60.120.260 26 157 1.8E-33 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_39890 ef81a3e0cb1454202f17ca23d0065f94 381 Pfam PF08787 Alginate lyase 169 379 8.3E-42 T 14-10-2018 IPR014895 Alginate lyase 2 A4R43_39890 ef81a3e0cb1454202f17ca23d0065f94 381 SUPERFAMILY SSF49899 162 380 1.58E-62 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_39890 ef81a3e0cb1454202f17ca23d0065f94 381 Pfam PF00754 F5/8 type C domain 35 149 7.8E-18 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4R43_17650 177222b7238cdc525dfa6a6f86bc7cca 593 SUPERFAMILY SSF55166 479 592 9.42E-25 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_17650 177222b7238cdc525dfa6a6f86bc7cca 593 SUPERFAMILY SSF54001 305 409 2.16E-17 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_17650 177222b7238cdc525dfa6a6f86bc7cca 593 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 482 592 4.9E-13 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A4R43_17650 177222b7238cdc525dfa6a6f86bc7cca 593 Gene3D G3DSA:3.90.1720.10 217 414 3.5E-24 T 14-10-2018 A4R43_17650 177222b7238cdc525dfa6a6f86bc7cca 593 Gene3D G3DSA:3.30.1380.10 477 593 3.5E-17 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_17650 177222b7238cdc525dfa6a6f86bc7cca 593 Pfam PF00877 NlpC/P60 family 324 397 4.2E-11 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_30115 80c2edf4854e1db592c5d45d33748ad1 431 SUPERFAMILY SSF58104 156 293 9.29E-6 T 14-10-2018 A4R43_30115 80c2edf4854e1db592c5d45d33748ad1 431 Pfam PF02470 MlaD protein 44 119 2.9E-14 T 14-10-2018 IPR003399 Mce/MlaD A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 SUPERFAMILY SSF53681 111 262 3.6E-39 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 Hamap MF_00258 Glutamate racemase [murI]. 6 259 36.621 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 Gene3D G3DSA:3.40.50.1860 7 257 3.0E-91 T 14-10-2018 A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 Gene3D G3DSA:3.40.50.1860 97 208 3.0E-91 T 14-10-2018 A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 SUPERFAMILY SSF53681 7 109 4.9E-32 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 4.6E-32 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 256 5.6E-66 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_36360 ba14b363e24760320cc8c159c010b6a0 268 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_14385 f0633f52c2cde7b93759c64d9333c03b 332 Gene3D G3DSA:3.40.50.1100 67 165 6.2E-114 T 14-10-2018 A4R43_14385 f0633f52c2cde7b93759c64d9333c03b 332 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 331 3.2E-162 T 14-10-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 A4R43_14385 f0633f52c2cde7b93759c64d9333c03b 332 PIRSF PIRSF006278 1 331 5.8E-120 T 14-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase A4R43_14385 f0633f52c2cde7b93759c64d9333c03b 332 SUPERFAMILY SSF53686 4 330 6.86E-96 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_14385 f0633f52c2cde7b93759c64d9333c03b 332 Gene3D G3DSA:3.40.50.1100 16 329 6.2E-114 T 14-10-2018 A4R43_14385 f0633f52c2cde7b93759c64d9333c03b 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 318 5.1E-48 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_38700 72964d740d1bfd5434bdb93e8786d2e5 126 ProSitePatterns PS01117 MarR-type HTH domain signature. 69 104 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_38700 72964d740d1bfd5434bdb93e8786d2e5 126 SMART SM00347 30 125 6.4E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38700 72964d740d1bfd5434bdb93e8786d2e5 126 Gene3D G3DSA:1.10.10.10 2 125 5.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38700 72964d740d1bfd5434bdb93e8786d2e5 126 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 1.8E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38700 72964d740d1bfd5434bdb93e8786d2e5 126 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 1.8E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38700 72964d740d1bfd5434bdb93e8786d2e5 126 Pfam PF12802 MarR family 36 95 6.7E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38700 72964d740d1bfd5434bdb93e8786d2e5 126 SUPERFAMILY SSF46785 13 123 1.6E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22290 14466d6c6cdc1a47f9df812b9ff7e1ef 204 SUPERFAMILY SSF109854 3 135 1.14E-13 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_22290 14466d6c6cdc1a47f9df812b9ff7e1ef 204 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 131 1.8E-6 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_22290 14466d6c6cdc1a47f9df812b9ff7e1ef 204 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 13 189 1.0E-17 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_22290 14466d6c6cdc1a47f9df812b9ff7e1ef 204 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 14 189 3.8E-40 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_17455 fa90d3d28094913bbf25ee0eed92679a 374 SUPERFAMILY SSF53383 2 371 7.32E-80 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_17455 fa90d3d28094913bbf25ee0eed92679a 374 Gene3D G3DSA:3.40.640.10 13 270 5.3E-92 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_17455 fa90d3d28094913bbf25ee0eed92679a 374 Gene3D G3DSA:3.90.1150.10 2 367 5.3E-92 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_17455 fa90d3d28094913bbf25ee0eed92679a 374 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 207 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A4R43_17455 fa90d3d28094913bbf25ee0eed92679a 374 Pfam PF00266 Aminotransferase class-V 2 365 1.9E-56 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_02040 acd25e8d2febffd7ea7651bf9e0b856d 389 Gene3D G3DSA:3.40.190.10 73 373 9.9E-64 T 14-10-2018 A4R43_02040 acd25e8d2febffd7ea7651bf9e0b856d 389 Pfam PF13416 Bacterial extracellular solute-binding protein 91 345 1.2E-17 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_02040 acd25e8d2febffd7ea7651bf9e0b856d 389 Gene3D G3DSA:3.40.190.10 174 377 9.9E-64 T 14-10-2018 A4R43_02040 acd25e8d2febffd7ea7651bf9e0b856d 389 SUPERFAMILY SSF53850 69 384 1.04E-41 T 14-10-2018 A4R43_13980 5adc9ff8455ae13202ea36efd5b72c2b 621 Pfam PF13641 Glycosyltransferase like family 2 249 472 8.2E-28 T 14-10-2018 A4R43_13980 5adc9ff8455ae13202ea36efd5b72c2b 621 Gene3D G3DSA:3.30.70.270 4 152 5.2E-12 T 14-10-2018 A4R43_13980 5adc9ff8455ae13202ea36efd5b72c2b 621 SUPERFAMILY SSF55073 9 148 7.53E-9 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_13980 5adc9ff8455ae13202ea36efd5b72c2b 621 Gene3D G3DSA:3.90.550.10 239 458 3.0E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_13980 5adc9ff8455ae13202ea36efd5b72c2b 621 SUPERFAMILY SSF53448 251 519 4.22E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_20160 013ed225e66fa697744de73af48d8c83 254 SUPERFAMILY SSF53335 24 193 5.52E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_20160 013ed225e66fa697744de73af48d8c83 254 Pfam PF08241 Methyltransferase domain 46 137 1.6E-16 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_20160 013ed225e66fa697744de73af48d8c83 254 Gene3D G3DSA:3.40.50.150 26 196 9.9E-34 T 14-10-2018 A4R43_28900 7c36b6286b8e7ae094b558bca165090f 179 Gene3D G3DSA:2.60.40.1220 24 123 8.0E-22 T 14-10-2018 A4R43_28900 7c36b6286b8e7ae094b558bca165090f 179 SUPERFAMILY SSF81296 23 118 1.75E-19 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_28900 7c36b6286b8e7ae094b558bca165090f 179 Pfam PF04234 CopC domain 24 117 3.2E-23 T 14-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 A4R43_17440 10ada980f7d72122e030cdd5b8363ada 169 Gene3D G3DSA:3.20.170.30 88 169 1.7E-28 T 14-10-2018 A4R43_17440 10ada980f7d72122e030cdd5b8363ada 169 SUPERFAMILY SSF56399 2 168 1.44E-54 T 14-10-2018 A4R43_17440 10ada980f7d72122e030cdd5b8363ada 169 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 1 168 29.443 T 14-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 A4R43_17440 10ada980f7d72122e030cdd5b8363ada 169 Gene3D G3DSA:1.10.10.970 1 68 5.0E-14 T 14-10-2018 A4R43_17440 10ada980f7d72122e030cdd5b8363ada 169 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 2 161 3.1E-39 T 14-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 A4R43_16035 431a0aa69892ea78c33ffeb00db0af3d 301 SUPERFAMILY SSF54593 1 275 3.48E-35 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16035 431a0aa69892ea78c33ffeb00db0af3d 301 Gene3D G3DSA:3.10.180.10 134 300 2.3E-56 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16035 431a0aa69892ea78c33ffeb00db0af3d 301 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 267 3.7E-21 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_16035 431a0aa69892ea78c33ffeb00db0af3d 301 Gene3D G3DSA:3.10.180.10 1 129 8.3E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16035 431a0aa69892ea78c33ffeb00db0af3d 301 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 245 266 - T 14-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 A4R43_03975 39168cbe597b6081db2ec33692bb8816 497 PIRSF PIRSF000654 34 275 4.9E-18 T 14-10-2018 A4R43_03975 39168cbe597b6081db2ec33692bb8816 497 Pfam PF00069 Protein kinase domain 20 265 7.1E-38 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_03975 39168cbe597b6081db2ec33692bb8816 497 Gene3D G3DSA:3.30.200.20 11 97 6.2E-20 T 14-10-2018 A4R43_03975 39168cbe597b6081db2ec33692bb8816 497 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 137 149 - T 14-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A4R43_03975 39168cbe597b6081db2ec33692bb8816 497 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 47 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_03975 39168cbe597b6081db2ec33692bb8816 497 SUPERFAMILY SSF56112 16 271 1.37E-60 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_03975 39168cbe597b6081db2ec33692bb8816 497 Gene3D G3DSA:1.10.510.10 99 276 8.3E-44 T 14-10-2018 A4R43_17280 27f09e572853ac13134b663261aee1df 106 Gene3D G3DSA:1.10.287.1060 1 99 6.6E-13 T 14-10-2018 A4R43_17280 27f09e572853ac13134b663261aee1df 106 SUPERFAMILY SSF140453 4 101 2.22E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_17280 27f09e572853ac13134b663261aee1df 106 Pfam PF06013 Proteins of 100 residues with WXG 4 93 7.7E-7 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_13545 103925b58ee1ec3dd02f98f7bd8fcb0d 503 SUPERFAMILY SSF53720 12 487 2.23E-163 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_13545 103925b58ee1ec3dd02f98f7bd8fcb0d 503 Gene3D G3DSA:3.40.605.10 18 479 2.6E-174 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_13545 103925b58ee1ec3dd02f98f7bd8fcb0d 503 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 14 496 2.7E-198 T 14-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 A4R43_13545 103925b58ee1ec3dd02f98f7bd8fcb0d 503 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_13545 103925b58ee1ec3dd02f98f7bd8fcb0d 503 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_13545 103925b58ee1ec3dd02f98f7bd8fcb0d 503 Pfam PF00171 Aldehyde dehydrogenase family 27 482 1.5E-167 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_13545 103925b58ee1ec3dd02f98f7bd8fcb0d 503 Gene3D G3DSA:3.40.309.10 263 453 2.6E-174 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_14290 7e10ac0ebebd01481d1a819be200a485 222 Pfam PF13761 Domain of unknown function (DUF4166) 15 200 2.8E-56 T 14-10-2018 IPR025311 Domain of unknown function DUF4166 A4R43_17575 50c22fc21cc3849a1a057a1b6345399e 352 Pfam PF01435 Peptidase family M48 72 266 6.1E-23 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4R43_17575 50c22fc21cc3849a1a057a1b6345399e 352 Gene3D G3DSA:3.30.2010.10 67 153 3.2E-11 T 14-10-2018 A4R43_25920 d940e8a357f2e9d303a0dd53e47fa6b1 215 Gene3D G3DSA:3.10.350.10 167 213 1.0E-10 T 14-10-2018 IPR036779 LysM domain superfamily A4R43_25920 d940e8a357f2e9d303a0dd53e47fa6b1 215 Pfam PF01476 LysM domain 168 212 1.4E-7 T 14-10-2018 IPR018392 LysM domain A4R43_25920 d940e8a357f2e9d303a0dd53e47fa6b1 215 Gene3D G3DSA:1.10.530.10 11 118 3.1E-36 T 14-10-2018 A4R43_25920 d940e8a357f2e9d303a0dd53e47fa6b1 215 SUPERFAMILY SSF53955 39 117 2.31E-31 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_25920 d940e8a357f2e9d303a0dd53e47fa6b1 215 SMART SM00257 167 215 3.1E-9 T 14-10-2018 IPR018392 LysM domain A4R43_25920 d940e8a357f2e9d303a0dd53e47fa6b1 215 Pfam PF06737 Transglycosylase-like domain 41 112 2.0E-33 T 14-10-2018 IPR010618 Transglycosylase-like A4R43_25920 d940e8a357f2e9d303a0dd53e47fa6b1 215 SUPERFAMILY SSF54106 168 212 6.28E-5 T 14-10-2018 A4R43_14155 b7f2232268dffcf5461e6eae39bf9b7d 396 Gene3D G3DSA:1.20.1530.20 4 385 2.2E-57 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily A4R43_14155 b7f2232268dffcf5461e6eae39bf9b7d 396 Pfam PF00999 Sodium/hydrogen exchanger family 14 371 1.3E-48 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4R43_12970 7bbb97f77ff7442dec23f86b7daee21b 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_12970 7bbb97f77ff7442dec23f86b7daee21b 250 Pfam PF00005 ABC transporter 21 172 7.0E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_12970 7bbb97f77ff7442dec23f86b7daee21b 250 SUPERFAMILY SSF52540 5 227 1.05E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12970 7bbb97f77ff7442dec23f86b7daee21b 250 SMART SM00382 30 240 9.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12970 7bbb97f77ff7442dec23f86b7daee21b 250 Gene3D G3DSA:3.40.50.300 2 240 4.2E-55 T 14-10-2018 A4R43_11895 62a23630977365f364dceccc5ea29234 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_11895 62a23630977365f364dceccc5ea29234 235 Gene3D G3DSA:3.40.50.300 1 235 6.2E-63 T 14-10-2018 A4R43_11895 62a23630977365f364dceccc5ea29234 235 SMART SM00382 26 220 1.4E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_11895 62a23630977365f364dceccc5ea29234 235 SUPERFAMILY SSF52540 2 233 5.75E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11895 62a23630977365f364dceccc5ea29234 235 Pfam PF00005 ABC transporter 17 162 3.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_24530 84695efab0038b7bb02329d3f7e77cd2 208 Pfam PF04972 BON domain 131 198 7.2E-10 T 14-10-2018 IPR007055 BON domain A4R43_24530 84695efab0038b7bb02329d3f7e77cd2 208 SUPERFAMILY SSF54631 1 127 2.42E-19 T 14-10-2018 A4R43_24530 84695efab0038b7bb02329d3f7e77cd2 208 SMART SM00116 1 48 6.5E-4 T 14-10-2018 IPR000644 CBS domain A4R43_24530 84695efab0038b7bb02329d3f7e77cd2 208 SMART SM00116 83 129 0.0054 T 14-10-2018 IPR000644 CBS domain A4R43_24530 84695efab0038b7bb02329d3f7e77cd2 208 Pfam PF00571 CBS domain 1 43 3.7E-6 T 14-10-2018 IPR000644 CBS domain A4R43_24530 84695efab0038b7bb02329d3f7e77cd2 208 Pfam PF00571 CBS domain 77 128 8.8E-8 T 14-10-2018 IPR000644 CBS domain A4R43_24530 84695efab0038b7bb02329d3f7e77cd2 208 Gene3D G3DSA:3.10.580.10 1 137 2.0E-21 T 14-10-2018 A4R43_32085 1281ade3906ca335b632aa14249577d5 248 Gene3D G3DSA:3.40.50.2300 2 122 9.5E-42 T 14-10-2018 A4R43_32085 1281ade3906ca335b632aa14249577d5 248 SUPERFAMILY SSF46894 123 222 1.21E-30 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_32085 1281ade3906ca335b632aa14249577d5 248 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 221 9.4E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_32085 1281ade3906ca335b632aa14249577d5 248 Gene3D G3DSA:1.10.10.10 123 226 1.2E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32085 1281ade3906ca335b632aa14249577d5 248 SMART SM00862 147 221 3.3E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_33795 c8e1b828b82e465274556c7d7c1272e2 362 SUPERFAMILY SSF51658 33 255 1.22E-27 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_33795 c8e1b828b82e465274556c7d7c1272e2 362 Gene3D G3DSA:3.20.20.150 31 255 8.7E-17 T 14-10-2018 A4R43_33795 c8e1b828b82e465274556c7d7c1272e2 362 Pfam PF01261 Xylose isomerase-like TIM barrel 41 230 1.3E-11 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_33795 c8e1b828b82e465274556c7d7c1272e2 362 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 195 202 - T 14-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A4R43_24155 480b91e53ce4e1e077dc6c3c429c5dce 580 SMART SM00220 308 561 8.1E-42 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_24155 480b91e53ce4e1e077dc6c3c429c5dce 580 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 424 436 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_24155 480b91e53ce4e1e077dc6c3c429c5dce 580 Gene3D G3DSA:3.30.200.20 268 386 1.5E-24 T 14-10-2018 A4R43_24155 480b91e53ce4e1e077dc6c3c429c5dce 580 Gene3D G3DSA:1.10.510.10 387 567 1.1E-31 T 14-10-2018 A4R43_24155 480b91e53ce4e1e077dc6c3c429c5dce 580 SUPERFAMILY SSF56112 292 555 9.31E-59 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_24155 480b91e53ce4e1e077dc6c3c429c5dce 580 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 314 337 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_24155 480b91e53ce4e1e077dc6c3c429c5dce 580 Pfam PF00069 Protein kinase domain 308 553 8.3E-41 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_00860 48b63c756d4b315672e0a784d5b7ced5 378 Gene3D G3DSA:3.30.565.10 249 374 2.3E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00860 48b63c756d4b315672e0a784d5b7ced5 378 SUPERFAMILY SSF55874 285 373 6.18E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00860 48b63c756d4b315672e0a784d5b7ced5 378 Pfam PF07730 Histidine kinase 184 248 1.0E-16 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 SUPERFAMILY SSF52954 568 674 9.82E-28 T 14-10-2018 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 78 668 7.0E-191 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 Gene3D G3DSA:3.30.980.10 75 246 7.6E-58 T 14-10-2018 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 Gene3D G3DSA:3.30.930.10 251 571 1.8E-113 T 14-10-2018 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 72 673 32.793 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 Pfam PF03129 Anticodon binding domain 580 669 2.4E-16 T 14-10-2018 IPR004154 Anticodon-binding A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 360 568 7.9E-35 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 PRINTS PR01047 Threonyl-tRNA synthetase signature 400 423 1.7E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 PRINTS PR01047 Threonyl-tRNA synthetase signature 546 559 1.7E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 PRINTS PR01047 Threonyl-tRNA synthetase signature 573 585 1.7E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 PRINTS PR01047 Threonyl-tRNA synthetase signature 367 395 1.7E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 PRINTS PR01047 Threonyl-tRNA synthetase signature 503 531 1.7E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 194 243 4.4E-13 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 SUPERFAMILY SSF55186 70 264 3.92E-51 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 SMART SM00863 187 243 6.7E-21 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 SUPERFAMILY SSF55681 267 564 6.13E-92 T 14-10-2018 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 Gene3D G3DSA:3.30.54.20 136 211 7.6E-58 T 14-10-2018 A4R43_04160 cfac11d2dcdfc52001f770aed53cb2c2 689 Gene3D G3DSA:3.40.50.800 572 679 1.2E-23 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily A4R43_11365 e0edc5ff1caed5bf20f35be59d0fd4bd 254 Gene3D G3DSA:3.60.10.10 2 253 1.9E-45 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_11365 e0edc5ff1caed5bf20f35be59d0fd4bd 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 245 3.6E-14 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4R43_11365 e0edc5ff1caed5bf20f35be59d0fd4bd 254 SUPERFAMILY SSF56219 1 252 3.4E-38 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_08640 aaa8f1f1a8fc746230061cb489bf8122 489 Gene3D G3DSA:3.30.300.310 390 489 2.6E-36 T 14-10-2018 A4R43_08640 aaa8f1f1a8fc746230061cb489bf8122 489 Pfam PF00501 AMP-binding enzyme 12 394 1.9E-111 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08640 aaa8f1f1a8fc746230061cb489bf8122 489 SUPERFAMILY SSF56801 9 488 5.23E-163 T 14-10-2018 A4R43_08640 aaa8f1f1a8fc746230061cb489bf8122 489 Pfam PF13193 AMP-binding enzyme C-terminal domain 403 478 4.6E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_08640 aaa8f1f1a8fc746230061cb489bf8122 489 Gene3D G3DSA:3.40.50.12780 3 387 2.3E-124 T 14-10-2018 A4R43_08640 aaa8f1f1a8fc746230061cb489bf8122 489 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 SMART SM00861 378 558 2.7E-71 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 Pfam PF02780 Transketolase, C-terminal domain 580 687 1.0E-13 T 14-10-2018 IPR033248 Transketolase, C-terminal domain A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 ProSitePatterns PS00801 Transketolase signature 1. 34 54 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 Pfam PF02779 Transketolase, pyrimidine binding domain 377 557 5.0E-47 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 26 361 2.1E-138 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 Gene3D G3DSA:3.40.50.970 7 357 7.1E-117 T 14-10-2018 A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 SUPERFAMILY SSF52518 21 347 2.64E-100 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 Gene3D G3DSA:3.40.50.970 358 569 3.1E-84 T 14-10-2018 A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 SUPERFAMILY SSF52518 371 560 2.27E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 SUPERFAMILY SSF52922 563 697 1.16E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 Gene3D G3DSA:3.40.50.920 570 697 1.2E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 ProSitePatterns PS00802 Transketolase signature 2. 500 516 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_04970 3911e8d4a4ca9ec1ab5c8299914e2d75 701 TIGRFAM TIGR00232 tktlase_bact: transketolase 29 693 3.7E-247 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A4R43_19290 dcf821790bf1f4a3db450f5560a8e15d 370 Pfam PF02625 XdhC and CoxI family 12 78 1.4E-20 T 14-10-2018 IPR003777 XdhC- CoxI A4R43_19290 dcf821790bf1f4a3db450f5560a8e15d 370 Pfam PF02625 XdhC and CoxI family 118 180 1.7E-19 T 14-10-2018 IPR003777 XdhC- CoxI A4R43_19290 dcf821790bf1f4a3db450f5560a8e15d 370 Gene3D G3DSA:3.40.50.720 202 355 9.5E-58 T 14-10-2018 A4R43_19290 dcf821790bf1f4a3db450f5560a8e15d 370 Pfam PF13478 XdhC Rossmann domain 203 349 3.5E-42 T 14-10-2018 IPR027051 XdhC Rossmann domain A4R43_13510 d0cda8fe8f0511036f70d8dca3409271 316 Gene3D G3DSA:3.20.20.100 6 305 1.2E-45 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_13510 d0cda8fe8f0511036f70d8dca3409271 316 SUPERFAMILY SSF51430 4 290 9.82E-46 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_13510 d0cda8fe8f0511036f70d8dca3409271 316 Pfam PF00248 Aldo/keto reductase family 19 290 1.1E-33 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 Pfam PF08281 Sigma-70, region 4 132 185 2.6E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 187 1.3E-26 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 SUPERFAMILY SSF88946 14 83 5.3E-23 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 7 319 4.0E-123 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 Gene3D G3DSA:1.10.10.10 115 191 4.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 SUPERFAMILY SSF88659 130 187 4.67E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 Pfam PF12680 SnoaL-like domain 208 285 1.8E-6 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 Gene3D G3DSA:1.10.1740.10 6 82 1.0E-23 T 14-10-2018 A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 SUPERFAMILY SSF54427 200 310 2.87E-18 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 34 65 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 Pfam PF04542 Sigma-70 region 2 15 79 6.5E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_17105 5c252b434e03b106f050a82f2473ce17 332 Gene3D G3DSA:3.10.450.50 196 318 1.7E-12 T 14-10-2018 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Gene3D G3DSA:1.10.287.610 1 67 9.5E-11 T 14-10-2018 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 105 134 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Gene3D G3DSA:1.10.150.20 483 562 1.6E-11 T 14-10-2018 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 SMART SM00532 2 426 1.9E-136 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 296 9.5E-68 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 299 373 1.2E-27 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 SMART SM00278 523 542 20.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 SMART SM00278 458 477 12.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 PIRSF PIRSF001604 1 660 1.6E-196 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Hamap MF_01588 DNA ligase [ligA]. 1 655 48.285 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Gene3D G3DSA:3.40.50.10190 573 659 3.3E-18 T 14-10-2018 IPR036420 BRCT domain superfamily A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Gene3D G3DSA:1.10.150.20 410 482 2.4E-20 T 14-10-2018 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 SUPERFAMILY SSF52113 576 653 1.22E-8 T 14-10-2018 IPR036420 BRCT domain superfamily A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 SMART SM00292 574 658 3.8E-6 T 14-10-2018 IPR001357 BRCT domain A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 12 649 3.6E-171 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 SUPERFAMILY SSF50249 296 373 1.32E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Gene3D G3DSA:2.40.50.140 297 384 1.1E-28 T 14-10-2018 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Pfam PF12826 Helix-hairpin-helix motif 489 543 2.4E-7 T 14-10-2018 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 SUPERFAMILY SSF47781 383 560 4.67E-42 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Gene3D G3DSA:3.30.1490.70 75 293 2.0E-63 T 14-10-2018 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 Gene3D G3DSA:3.30.470.30 69 232 2.0E-63 T 14-10-2018 A4R43_07250 0087d1f3f849e41187a2c61aa29ec41f 661 SUPERFAMILY SSF56091 2 296 4.75E-74 T 14-10-2018 A4R43_26795 d0c1b55f13160440788942400b8f681d 316 Pfam PF13411 MerR HTH family regulatory protein 12 79 8.5E-19 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_26795 d0c1b55f13160440788942400b8f681d 316 Gene3D G3DSA:1.10.1660.10 14 214 3.9E-32 T 14-10-2018 A4R43_26795 d0c1b55f13160440788942400b8f681d 316 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 24 6.4E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_26795 d0c1b55f13160440788942400b8f681d 316 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 24 37 6.4E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_26795 d0c1b55f13160440788942400b8f681d 316 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 48 68 6.4E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_26795 d0c1b55f13160440788942400b8f681d 316 SMART SM00422 12 81 8.8E-26 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_26795 d0c1b55f13160440788942400b8f681d 316 SUPERFAMILY SSF46955 12 116 1.17E-26 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_05785 c94bc06acbe95e3137d5b99dbecf9f97 324 SUPERFAMILY SSF48179 196 317 2.72E-26 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_05785 c94bc06acbe95e3137d5b99dbecf9f97 324 Gene3D G3DSA:1.10.1040.10 196 323 5.8E-37 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_05785 c94bc06acbe95e3137d5b99dbecf9f97 324 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 169 8.1E-25 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A4R43_05785 c94bc06acbe95e3137d5b99dbecf9f97 324 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 196 315 4.3E-28 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A4R43_05785 c94bc06acbe95e3137d5b99dbecf9f97 324 SUPERFAMILY SSF51735 2 156 3.25E-12 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05785 c94bc06acbe95e3137d5b99dbecf9f97 324 Gene3D G3DSA:3.40.50.720 1 194 1.7E-61 T 14-10-2018 A4R43_41065 aa5f1141ea4ecbcac3743ee4d59b577e 97 SUPERFAMILY SSF103007 1 95 7.45E-31 T 14-10-2018 IPR036746 TT1725-like superfamily A4R43_41065 aa5f1141ea4ecbcac3743ee4d59b577e 97 Gene3D G3DSA:3.30.70.1120 1 94 7.4E-24 T 14-10-2018 IPR036746 TT1725-like superfamily A4R43_41065 aa5f1141ea4ecbcac3743ee4d59b577e 97 Pfam PF04456 Protein of unknown function (DUF503) 3 89 2.9E-32 T 14-10-2018 IPR007546 Protein of unknown function DUF503 A4R43_17380 e7ed1eaff74c1e2e7238cb89896ced4c 158 Gene3D G3DSA:1.10.3450.10 21 157 4.5E-14 T 14-10-2018 A4R43_17380 e7ed1eaff74c1e2e7238cb89896ced4c 158 SUPERFAMILY SSF140663 26 141 2.09E-27 T 14-10-2018 IPR023203 TTHA0068-like superfamily A4R43_17380 e7ed1eaff74c1e2e7238cb89896ced4c 158 Pfam PF03745 Domain of unknown function (DUF309) 45 102 2.8E-17 T 14-10-2018 IPR005500 Protein of unknown function DUF309 A4R43_08565 bdc6b9a526e1b19b3cd847612d66b68a 130 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 6.7E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_08565 bdc6b9a526e1b19b3cd847612d66b68a 130 Gene3D G3DSA:1.10.10.10 12 128 3.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08565 bdc6b9a526e1b19b3cd847612d66b68a 130 SMART SM00345 18 77 3.2E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_08565 bdc6b9a526e1b19b3cd847612d66b68a 130 SUPERFAMILY SSF46785 9 80 4.67E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 106 124 2.0E-28 T 14-10-2018 A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 124 143 2.0E-28 T 14-10-2018 A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 276 295 2.0E-28 T 14-10-2018 A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 2.0E-28 T 14-10-2018 A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 464 479 2.0E-28 T 14-10-2018 A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 488 505 2.0E-28 T 14-10-2018 A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 SUPERFAMILY SSF56235 3 593 5.79E-130 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 Gene3D G3DSA:3.60.20.40 410 598 2.4E-42 T 14-10-2018 A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 Pfam PF01019 Gamma-glutamyltranspeptidase 29 594 2.3E-116 T 14-10-2018 A4R43_02235 18916467fc393d6378914dfdb16bb2b3 601 Gene3D G3DSA:1.10.246.130 263 386 1.3E-27 T 14-10-2018 A4R43_01420 89a0e0fe635fe5e4d82fb53982e81c15 115 SUPERFAMILY SSF82607 19 98 3.92E-8 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_01420 89a0e0fe635fe5e4d82fb53982e81c15 115 Gene3D G3DSA:3.30.1310.10 8 106 6.8E-8 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_01420 89a0e0fe635fe5e4d82fb53982e81c15 115 Pfam PF02575 YbaB/EbfC DNA-binding family 15 97 8.2E-12 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_30445 0bbb34a9f2634d2e7a6dd5bb1691c3f9 182 Gene3D G3DSA:3.30.300.20 35 117 3.3E-15 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_30445 0bbb34a9f2634d2e7a6dd5bb1691c3f9 182 Pfam PF01424 R3H domain 122 181 2.5E-15 T 14-10-2018 IPR001374 R3H domain GO:0003676 A4R43_30445 0bbb34a9f2634d2e7a6dd5bb1691c3f9 182 Gene3D G3DSA:3.30.1370.50 118 182 1.0E-21 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 A4R43_30445 0bbb34a9f2634d2e7a6dd5bb1691c3f9 182 SMART SM00393 103 182 7.2E-27 T 14-10-2018 IPR001374 R3H domain GO:0003676 A4R43_30445 0bbb34a9f2634d2e7a6dd5bb1691c3f9 182 SUPERFAMILY SSF82708 133 181 1.1E-10 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 A4R43_19335 5c36d410b8423f86b43614464c996847 351 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 5 339 6.6E-148 T 14-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 A4R43_19335 5c36d410b8423f86b43614464c996847 351 Pfam PF02378 Phosphotransferase system, EIIC 15 273 1.5E-9 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A4R43_04390 70f333fdaa5df5befc6c79b1730c7cd6 262 Pfam PF09339 IclR helix-turn-helix domain 16 65 1.4E-9 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_04390 70f333fdaa5df5befc6c79b1730c7cd6 262 Gene3D G3DSA:1.10.10.10 9 85 8.9E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04390 70f333fdaa5df5befc6c79b1730c7cd6 262 SMART SM00346 14 106 2.0E-7 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_04390 70f333fdaa5df5befc6c79b1730c7cd6 262 SUPERFAMILY SSF55781 81 261 9.81E-41 T 14-10-2018 A4R43_04390 70f333fdaa5df5befc6c79b1730c7cd6 262 SUPERFAMILY SSF46785 16 88 5.0E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04390 70f333fdaa5df5befc6c79b1730c7cd6 262 Pfam PF01614 Bacterial transcriptional regulator 141 258 1.5E-18 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_04390 70f333fdaa5df5befc6c79b1730c7cd6 262 Gene3D G3DSA:3.30.450.40 89 262 1.6E-42 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_21530 cce5e30c22323355d64bd8e536937f5e 236 Gene3D G3DSA:3.40.50.720 1 185 1.1E-42 T 14-10-2018 A4R43_21530 cce5e30c22323355d64bd8e536937f5e 236 SUPERFAMILY SSF51735 2 187 2.0E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_21530 cce5e30c22323355d64bd8e536937f5e 236 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 82 2.2E-10 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 9.0E-33 T 14-10-2018 A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 9.0E-33 T 14-10-2018 A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 341 9.0E-33 T 14-10-2018 A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 9.0E-33 T 14-10-2018 A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 9.0E-33 T 14-10-2018 A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 SUPERFAMILY SSF51905 4 369 2.63E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 Pfam PF01494 FAD binding domain 4 354 2.0E-62 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 Gene3D G3DSA:3.50.50.60 271 399 7.9E-31 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 Gene3D G3DSA:3.50.50.60 2 192 2.5E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 Gene3D G3DSA:3.40.30.120 400 507 1.7E-25 T 14-10-2018 A4R43_03445 1e1f2df3910b5128c153a883e6505f4e 521 Gene3D G3DSA:3.30.70.2450 193 268 2.3E-7 T 14-10-2018 A4R43_27730 21aa71b50498906823a2f7d62ef33cfd 378 Pfam PF07730 Histidine kinase 188 248 1.7E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_27730 21aa71b50498906823a2f7d62ef33cfd 378 SUPERFAMILY SSF55874 266 375 1.09E-5 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27730 21aa71b50498906823a2f7d62ef33cfd 378 Gene3D G3DSA:3.30.565.10 253 377 1.8E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_01930 92c8f8aa2ec51ef3ab18b4fb0c878479 194 SUPERFAMILY SSF48498 90 183 5.0E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_01930 92c8f8aa2ec51ef3ab18b4fb0c878479 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01930 92c8f8aa2ec51ef3ab18b4fb0c878479 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01930 92c8f8aa2ec51ef3ab18b4fb0c878479 194 SUPERFAMILY SSF46689 4 85 1.18E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01930 92c8f8aa2ec51ef3ab18b4fb0c878479 194 Gene3D G3DSA:1.10.357.10 5 193 9.1E-38 T 14-10-2018 A4R43_01930 92c8f8aa2ec51ef3ab18b4fb0c878479 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 9.3E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Gene3D G3DSA:3.40.50.720 208 333 7.1E-42 T 14-10-2018 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Gene3D G3DSA:3.30.470.20 677 876 7.0E-61 T 14-10-2018 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 SUPERFAMILY SSF56059 684 881 4.09E-24 T 14-10-2018 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 SUPERFAMILY SSF55729 31 172 8.23E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Gene3D G3DSA:3.30.1490.20 695 765 7.0E-61 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Pfam PF13380 CoA binding domain 213 338 2.1E-22 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Pfam PF00583 Acetyltransferase (GNAT) family 64 167 2.7E-11 T 14-10-2018 IPR000182 GNAT domain A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Gene3D G3DSA:3.40.50.261 529 648 9.7E-18 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 SUPERFAMILY SSF51735 204 341 1.32E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 357 490 6.4E-44 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Pfam PF13549 ATP-grasp domain 674 881 1.9E-55 T 14-10-2018 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Gene3D G3DSA:3.40.50.261 335 494 1.2E-51 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 SUPERFAMILY SSF52210 497 642 8.24E-23 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 SUPERFAMILY SSF52210 335 494 6.54E-37 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 SMART SM00881 209 304 9.7E-35 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Gene3D G3DSA:3.40.50.261 495 528 5.8E-5 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_16670 2ec1e1a927b8572fe3506884be7c0387 903 Gene3D G3DSA:3.40.630.30 24 207 1.2E-50 T 14-10-2018 A4R43_10385 bd33499b24fe2d43abb6204f302f76fb 382 SUPERFAMILY SSF75005 70 373 1.08E-65 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_10385 bd33499b24fe2d43abb6204f302f76fb 382 PIRSF PIRSF025414 43 378 1.3E-130 T 14-10-2018 IPR016828 Alpha-L-arabinofuranosidase KEGG: 00520+3.2.1.55 A4R43_10385 bd33499b24fe2d43abb6204f302f76fb 382 Pfam PF04616 Glycosyl hydrolases family 43 70 365 3.0E-65 T 14-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4R43_10385 bd33499b24fe2d43abb6204f302f76fb 382 Gene3D G3DSA:2.115.10.20 62 374 3.4E-93 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 33 85 1.7E-23 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 13 656 50.279 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 653 8.7E-286 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 Gene3D G3DSA:3.40.50.12780 57 524 3.8E-102 T 14-10-2018 A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 Gene3D G3DSA:3.30.300.30 527 659 2.3E-30 T 14-10-2018 A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 SUPERFAMILY SSF56801 28 652 5.89E-171 T 14-10-2018 A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 Pfam PF00501 AMP-binding enzyme 93 531 2.1E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_27085 6d1c163d98ee613f39a1374b662df5fd 663 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 622 4.4E-26 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_04840 13188e5f3889227e457f6a583523d37e 234 Gene3D G3DSA:2.40.10.10 105 232 5.2E-15 T 14-10-2018 A4R43_04840 13188e5f3889227e457f6a583523d37e 234 Gene3D G3DSA:2.40.10.10 36 104 1.2E-13 T 14-10-2018 A4R43_04840 13188e5f3889227e457f6a583523d37e 234 SMART SM00020 35 228 2.3E-12 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_04840 13188e5f3889227e457f6a583523d37e 234 SUPERFAMILY SSF50494 22 232 9.7E-38 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_04840 13188e5f3889227e457f6a583523d37e 234 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 60 75 9.9E-11 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_04840 13188e5f3889227e457f6a583523d37e 234 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 103 117 9.9E-11 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_04840 13188e5f3889227e457f6a583523d37e 234 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 180 192 9.9E-11 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_04840 13188e5f3889227e457f6a583523d37e 234 Pfam PF00089 Trypsin 36 228 1.2E-26 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_40920 53f1ae848b89f0477280c4ad3949fe00 321 SUPERFAMILY SSF53613 2 289 6.86E-57 T 14-10-2018 IPR029056 Ribokinase-like A4R43_40920 53f1ae848b89f0477280c4ad3949fe00 321 Pfam PF00294 pfkB family carbohydrate kinase 32 289 3.1E-42 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_40920 53f1ae848b89f0477280c4ad3949fe00 321 Gene3D G3DSA:3.40.1190.20 1 317 1.3E-84 T 14-10-2018 IPR029056 Ribokinase-like A4R43_40920 53f1ae848b89f0477280c4ad3949fe00 321 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_40920 53f1ae848b89f0477280c4ad3949fe00 321 PRINTS PR00990 Ribokinase signature 42 61 8.8E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_40920 53f1ae848b89f0477280c4ad3949fe00 321 PRINTS PR00990 Ribokinase signature 180 195 8.8E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_40920 53f1ae848b89f0477280c4ad3949fe00 321 PRINTS PR00990 Ribokinase signature 216 227 8.8E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_29360 aa91782243d2a85109b8fddeadbc49e9 111 SUPERFAMILY SSF46565 5 71 6.41E-17 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_29360 aa91782243d2a85109b8fddeadbc49e9 111 PRINTS PR00625 DnaJ domain signature 30 45 1.9E-9 T 14-10-2018 IPR001623 DnaJ domain A4R43_29360 aa91782243d2a85109b8fddeadbc49e9 111 PRINTS PR00625 DnaJ domain signature 12 30 1.9E-9 T 14-10-2018 IPR001623 DnaJ domain A4R43_29360 aa91782243d2a85109b8fddeadbc49e9 111 PRINTS PR00625 DnaJ domain signature 46 66 1.9E-9 T 14-10-2018 IPR001623 DnaJ domain A4R43_29360 aa91782243d2a85109b8fddeadbc49e9 111 Gene3D G3DSA:1.10.287.110 8 92 8.1E-17 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_29360 aa91782243d2a85109b8fddeadbc49e9 111 SMART SM00271 9 66 7.1E-14 T 14-10-2018 IPR001623 DnaJ domain A4R43_29360 aa91782243d2a85109b8fddeadbc49e9 111 Pfam PF00226 DnaJ domain 10 68 5.5E-14 T 14-10-2018 IPR001623 DnaJ domain A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 Gene3D G3DSA:3.90.230.10 1 261 4.1E-81 T 14-10-2018 A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 SUPERFAMILY SSF55920 2 253 1.44E-72 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 Pfam PF00557 Metallopeptidase family M24 12 245 6.4E-44 T 14-10-2018 IPR000994 Peptidase M24 A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 1.0E-73 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 9.6E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 9.6E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 9.6E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 9.6E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_01360 71645e726943d7a5ed53d19fdb15ced9 273 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 33.363 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_19170 814d6063fa3bdfecad8c50aa40cb478b 454 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_19170 814d6063fa3bdfecad8c50aa40cb478b 454 Pfam PF00171 Aldehyde dehydrogenase family 3 449 4.4E-159 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_19170 814d6063fa3bdfecad8c50aa40cb478b 454 SUPERFAMILY SSF53720 3 451 1.57E-156 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_19170 814d6063fa3bdfecad8c50aa40cb478b 454 Gene3D G3DSA:3.40.309.10 235 420 3.5E-167 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_19170 814d6063fa3bdfecad8c50aa40cb478b 454 Gene3D G3DSA:3.40.605.10 4 449 3.5E-167 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_19170 814d6063fa3bdfecad8c50aa40cb478b 454 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 SUPERFAMILY SSF54427 184 292 2.15E-10 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 Gene3D G3DSA:1.10.1740.10 5 88 2.1E-8 T 14-10-2018 A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 Pfam PF04542 Sigma-70 region 2 22 85 7.7E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 SUPERFAMILY SSF88659 86 171 2.06E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 169 3.7E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 SUPERFAMILY SSF88946 16 81 1.18E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 Pfam PF08281 Sigma-70, region 4 117 168 1.1E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 19 293 3.8E-105 T 14-10-2018 IPR014303 RNA polymerase sigma-70, ECF type A4R43_00630 adc28a0256b5957d080a3ec1702fe78e 301 Gene3D G3DSA:1.10.10.10 101 173 2.0E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20310 bc19cab5f703adffe8d52d988873c5eb 125 SMART SM00422 1 69 4.0E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20310 bc19cab5f703adffe8d52d988873c5eb 125 Gene3D G3DSA:1.10.1660.10 1 125 9.6E-28 T 14-10-2018 A4R43_20310 bc19cab5f703adffe8d52d988873c5eb 125 Pfam PF13411 MerR HTH family regulatory protein 1 67 3.8E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20310 bc19cab5f703adffe8d52d988873c5eb 125 SUPERFAMILY SSF46955 1 114 2.27E-23 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_20310 bc19cab5f703adffe8d52d988873c5eb 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.7E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20310 bc19cab5f703adffe8d52d988873c5eb 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.7E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20310 bc19cab5f703adffe8d52d988873c5eb 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.7E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 Gene3D G3DSA:3.40.50.620 1 157 2.4E-54 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 Pfam PF01467 Cytidylyltransferase-like 6 132 6.2E-19 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 SUPERFAMILY SSF52374 1 154 5.89E-46 T 14-10-2018 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 63 5.0E-16 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 5.7E-50 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 5.7E-50 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 5.7E-50 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 5.7E-50 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 5.7E-50 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 155 3.0E-5 T 14-10-2018 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 33.609 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4R43_18785 2cc007584bf37b24fd981e889edff29f 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 154 2.8E-57 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4R43_21020 a60f160d985aa536782c9b8af72087f4 332 SUPERFAMILY SSF53850 39 258 1.75E-41 T 14-10-2018 A4R43_21020 a60f160d985aa536782c9b8af72087f4 332 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 41 322 4.2E-55 T 14-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 A4R43_21020 a60f160d985aa536782c9b8af72087f4 332 Gene3D G3DSA:3.40.190.10 116 215 8.7E-87 T 14-10-2018 A4R43_21020 a60f160d985aa536782c9b8af72087f4 332 Gene3D G3DSA:3.40.190.10 41 313 8.7E-87 T 14-10-2018 A4R43_21020 a60f160d985aa536782c9b8af72087f4 332 Gene3D G3DSA:1.10.8.450 249 281 8.7E-87 T 14-10-2018 A4R43_21020 a60f160d985aa536782c9b8af72087f4 332 SMART SM00062 40 254 0.0026 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_21020 a60f160d985aa536782c9b8af72087f4 332 Pfam PF13379 NMT1-like family 66 262 7.7E-11 T 14-10-2018 A4R43_26695 cc739937f50830295cda89c84adbe294 353 SUPERFAMILY SSF55846 45 221 9.68E-41 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_26695 cc739937f50830295cda89c84adbe294 353 Gene3D G3DSA:3.40.80.10 40 223 1.2E-45 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_26695 cc739937f50830295cda89c84adbe294 353 Gene3D G3DSA:1.10.101.10 228 311 5.3E-9 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_26695 cc739937f50830295cda89c84adbe294 353 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 67 206 5.1E-17 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_26695 cc739937f50830295cda89c84adbe294 353 SMART SM00644 59 206 3.2E-7 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_26695 cc739937f50830295cda89c84adbe294 353 SUPERFAMILY SSF47090 232 285 3.18E-7 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_26695 cc739937f50830295cda89c84adbe294 353 SMART SM00701 45 200 7.2E-4 T 14-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A4R43_15145 c69440cd0ad6e452f8ef642d7e76c347 113 Pfam PF03551 Transcriptional regulator PadR-like family 23 93 4.0E-15 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_15145 c69440cd0ad6e452f8ef642d7e76c347 113 SUPERFAMILY SSF46785 16 100 8.92E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15145 c69440cd0ad6e452f8ef642d7e76c347 113 Gene3D G3DSA:1.10.10.10 11 106 3.2E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 28 354 40.364 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 Pfam PF06463 Molybdenum Cofactor Synthesis C 210 336 1.4E-36 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 28 354 9.1E-112 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 43 54 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 Pfam PF04055 Radical SAM superfamily 42 202 3.1E-30 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 SMART SM00729 37 242 1.0E-6 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 Gene3D G3DSA:3.20.20.70 26 354 1.2E-90 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 Pfam PF13353 4Fe-4S single cluster domain 44 132 1.2E-6 T 14-10-2018 A4R43_25905 4f98addf9cc26d522f29bd2ea7760e4e 354 SUPERFAMILY SSF102114 27 326 4.45E-74 T 14-10-2018 A4R43_26270 7673f164336444520eae38f8e6853746 301 Gene3D G3DSA:2.60.120.620 4 300 3.7E-102 T 14-10-2018 A4R43_26270 7673f164336444520eae38f8e6853746 301 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 26 300 1.9E-133 T 14-10-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 A4R43_26270 7673f164336444520eae38f8e6853746 301 SUPERFAMILY SSF51197 38 299 1.37E-58 T 14-10-2018 A4R43_26270 7673f164336444520eae38f8e6853746 301 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 50 263 7.6E-35 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase A4R43_38730 ee02eb66573adabc8fceb60d28e022a5 376 SUPERFAMILY SSF50494 196 356 3.61E-13 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_38730 ee02eb66573adabc8fceb60d28e022a5 376 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 327 338 - T 14-10-2018 IPR033116 Serine proteases, trypsin family, serine active site A4R43_38730 ee02eb66573adabc8fceb60d28e022a5 376 Gene3D G3DSA:2.40.10.10 189 372 5.2E-20 T 14-10-2018 A4R43_38730 ee02eb66573adabc8fceb60d28e022a5 376 Gene3D G3DSA:2.40.10.10 261 363 5.2E-20 T 14-10-2018 A4R43_39440 e21704410214f163b82da4582929ff02 180 Pfam PF06445 GyrI-like small molecule binding domain 14 177 8.1E-13 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain A4R43_39440 e21704410214f163b82da4582929ff02 180 SUPERFAMILY SSF55136 108 173 1.73E-5 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A4R43_39440 e21704410214f163b82da4582929ff02 180 Gene3D G3DSA:3.20.80.10 1 179 3.7E-50 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A4R43_01670 4451182f1d5a5e5b48dc4f447b11c3ee 321 SMART SM00470 4 88 4.4E-11 T 14-10-2018 IPR003115 ParB/Sulfiredoxin A4R43_01670 4451182f1d5a5e5b48dc4f447b11c3ee 321 Pfam PF02195 ParB-like nuclease domain 6 88 1.9E-7 T 14-10-2018 IPR003115 ParB/Sulfiredoxin A4R43_01670 4451182f1d5a5e5b48dc4f447b11c3ee 321 SUPERFAMILY SSF110849 4 89 1.27E-7 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A4R43_22450 2dc7028a9da24f91834c006a9e4d0c64 348 Gene3D G3DSA:3.40.50.1100 57 153 7.5E-122 T 14-10-2018 A4R43_22450 2dc7028a9da24f91834c006a9e4d0c64 348 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 315 1.7E-67 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_22450 2dc7028a9da24f91834c006a9e4d0c64 348 PIRSF PIRSF038945 1 347 1.5E-158 T 14-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A4R43_22450 2dc7028a9da24f91834c006a9e4d0c64 348 TIGRFAM TIGR00260 thrC: threonine synthase 7 321 2.7E-89 T 14-10-2018 IPR004450 Threonine synthase-like A4R43_22450 2dc7028a9da24f91834c006a9e4d0c64 348 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 49 62 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4R43_22450 2dc7028a9da24f91834c006a9e4d0c64 348 Gene3D G3DSA:3.40.50.1100 12 321 7.5E-122 T 14-10-2018 A4R43_22450 2dc7028a9da24f91834c006a9e4d0c64 348 SUPERFAMILY SSF53686 3 326 5.37E-98 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.4E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.4E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.4E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 SUPERFAMILY SSF46785 1 59 7.35E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 3.7E-14 T 14-10-2018 A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 Gene3D G3DSA:3.30.70.920 52 145 1.4E-19 T 14-10-2018 A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 Pfam PF01037 Lrp/AsnC ligand binding domain 76 140 5.3E-16 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 SMART SM00344 1 110 8.4E-37 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 SUPERFAMILY SSF54909 63 149 9.25E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_37600 7fb8f1c60cef799c5c0db8687b8ed918 153 Gene3D G3DSA:1.10.10.10 4 51 8.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18335 06a656fb18745710bc293436e868ab71 402 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 158 241 8.4E-36 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4R43_18335 06a656fb18745710bc293436e868ab71 402 PIRSF PIRSF006205 4 401 6.3E-136 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4R43_18335 06a656fb18745710bc293436e868ab71 402 SUPERFAMILY SSF69055 305 396 5.89E-24 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4R43_18335 06a656fb18745710bc293436e868ab71 402 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 7 396 42.803 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4R43_18335 06a656fb18745710bc293436e868ab71 402 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 8 146 8.2E-34 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4R43_18335 06a656fb18745710bc293436e868ab71 402 Gene3D G3DSA:3.40.50.720 2 162 8.6E-43 T 14-10-2018 A4R43_18335 06a656fb18745710bc293436e868ab71 402 Pfam PF13288 DXP reductoisomerase C-terminal domain 274 391 2.3E-35 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4R43_18335 06a656fb18745710bc293436e868ab71 402 SUPERFAMILY SSF51735 5 162 6.27E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_18335 06a656fb18745710bc293436e868ab71 402 Gene3D G3DSA:1.10.1740.10 314 398 3.2E-26 T 14-10-2018 A4R43_18335 06a656fb18745710bc293436e868ab71 402 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 394 1.2E-113 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4R43_18335 06a656fb18745710bc293436e868ab71 402 SUPERFAMILY SSF55347 140 276 6.54E-53 T 14-10-2018 A4R43_20050 cce7a43fac015c92795895680ff072d6 504 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 486 91.181 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_20050 cce7a43fac015c92795895680ff072d6 504 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 483 2.3E-188 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_20050 cce7a43fac015c92795895680ff072d6 504 PIRSF PIRSF001221 451 486 5.6 T 14-10-2018 A4R43_20050 cce7a43fac015c92795895680ff072d6 504 PIRSF PIRSF001221 2 441 3.7E-43 T 14-10-2018 A4R43_20050 cce7a43fac015c92795895680ff072d6 504 Pfam PF01425 Amidase 25 474 4.1E-160 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_20050 cce7a43fac015c92795895680ff072d6 504 Gene3D G3DSA:3.90.1300.10 3 493 2.6E-187 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_20050 cce7a43fac015c92795895680ff072d6 504 SUPERFAMILY SSF75304 2 483 2.22E-160 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_20050 cce7a43fac015c92795895680ff072d6 504 ProSitePatterns PS00571 Amidases signature. 153 184 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 Gene3D G3DSA:3.40.50.300 253 422 3.3E-40 T 14-10-2018 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 Pfam PF13167 GTP-binding GTPase N-terminal 72 160 2.5E-33 T 14-10-2018 IPR025121 GTPase HflX, N-terminal A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 56 418 3.3E-134 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 Gene3D G3DSA:3.40.50.11060 65 187 8.0E-42 T 14-10-2018 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 Pfam PF16360 GTP-binding GTPase Middle Region 162 248 7.0E-29 T 14-10-2018 IPR032305 GTP-binding protein, middle domain A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 SUPERFAMILY SSF52540 255 447 3.73E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 Hamap MF_00900 GTPase HflX [hflX]. 75 448 49.242 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 256 276 1.2E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 323 341 1.2E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 PIRSF PIRSF006809 47 479 6.8E-160 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 PIRSF PIRSF006809 19 54 230.0 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 A4R43_16830 59e3c5b39d534df6ff0a7333b1eef23b 481 Pfam PF01926 50S ribosome-binding GTPase 256 378 1.2E-20 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_04140 99f808f03bbb118b53584ac31c103e40 104 Gene3D G3DSA:1.10.3730.20 1 104 1.3E-25 T 14-10-2018 A4R43_04140 99f808f03bbb118b53584ac31c103e40 104 SUPERFAMILY SSF103481 6 102 6.41E-15 T 14-10-2018 A4R43_04140 99f808f03bbb118b53584ac31c103e40 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 7.3E-20 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A4R43_14615 a25d4b7f0b44d5205b4a3af2e924845a 496 Gene3D G3DSA:3.30.420.40 2 240 5.4E-73 T 14-10-2018 A4R43_14615 a25d4b7f0b44d5205b4a3af2e924845a 496 Gene3D G3DSA:3.30.420.40 242 493 8.9E-71 T 14-10-2018 A4R43_14615 a25d4b7f0b44d5205b4a3af2e924845a 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 440 7.8E-37 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4R43_14615 a25d4b7f0b44d5205b4a3af2e924845a 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 353 373 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_14615 a25d4b7f0b44d5205b4a3af2e924845a 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 245 7.3E-50 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4R43_14615 a25d4b7f0b44d5205b4a3af2e924845a 496 SUPERFAMILY SSF53067 6 252 1.36E-56 T 14-10-2018 A4R43_14615 a25d4b7f0b44d5205b4a3af2e924845a 496 SUPERFAMILY SSF53067 251 484 6.47E-61 T 14-10-2018 A4R43_14615 a25d4b7f0b44d5205b4a3af2e924845a 496 PIRSF PIRSF000538 3 490 3.3E-129 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_10710 cec3f423bed35b77716c66c089396f69 923 SMART SM00490 354 440 1.4E-12 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_10710 cec3f423bed35b77716c66c089396f69 923 SMART SM01142 747 923 1.1E-59 T 14-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal A4R43_10710 cec3f423bed35b77716c66c089396f69 923 SMART SM00487 32 214 3.1E-30 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_10710 cec3f423bed35b77716c66c089396f69 923 SUPERFAMILY SSF52540 45 454 1.27E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10710 cec3f423bed35b77716c66c089396f69 923 Pfam PF08148 DSHCT (NUC185) domain 752 919 1.2E-36 T 14-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal A4R43_10710 cec3f423bed35b77716c66c089396f69 923 Pfam PF13234 rRNA-processing arch domain 497 596 7.6E-5 T 14-10-2018 IPR025696 rRNA-processing arch domain A4R43_10710 cec3f423bed35b77716c66c089396f69 923 Pfam PF00271 Helicase conserved C-terminal domain 364 440 4.8E-5 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_10710 cec3f423bed35b77716c66c089396f69 923 Gene3D G3DSA:3.40.50.300 12 209 5.9E-63 T 14-10-2018 A4R43_10710 cec3f423bed35b77716c66c089396f69 923 Pfam PF00270 DEAD/DEAH box helicase 39 185 1.4E-18 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_10710 cec3f423bed35b77716c66c089396f69 923 Gene3D G3DSA:3.40.50.300 210 471 8.9E-56 T 14-10-2018 A4R43_10710 cec3f423bed35b77716c66c089396f69 923 Gene3D G3DSA:1.10.3380.30 703 913 1.1E-15 T 14-10-2018 A4R43_11385 c8a21236d6fb3e2919acad494f045bec 196 SUPERFAMILY SSF48498 91 190 3.11E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11385 c8a21236d6fb3e2919acad494f045bec 196 SUPERFAMILY SSF46689 14 85 1.08E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11385 c8a21236d6fb3e2919acad494f045bec 196 Gene3D G3DSA:1.10.357.10 9 196 5.5E-21 T 14-10-2018 A4R43_20955 ecd5c4eed1283623cc6c3d18102331c9 433 Gene3D G3DSA:3.30.565.10 120 269 1.9E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_20955 ecd5c4eed1283623cc6c3d18102331c9 433 SUPERFAMILY SSF55874 156 271 1.7E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_20955 ecd5c4eed1283623cc6c3d18102331c9 433 Gene3D G3DSA:1.10.287.130 73 119 1.9E-17 T 14-10-2018 A4R43_20955 ecd5c4eed1283623cc6c3d18102331c9 433 SMART SM00387 161 272 2.7E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_20955 ecd5c4eed1283623cc6c3d18102331c9 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 165 271 1.1E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_10170 23630a6b8d849e80ba5e84c71734977f 361 Gene3D G3DSA:1.10.260.40 5 76 2.0E-9 T 14-10-2018 A4R43_10170 23630a6b8d849e80ba5e84c71734977f 361 SUPERFAMILY SSF47413 10 76 2.17E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_10170 23630a6b8d849e80ba5e84c71734977f 361 Pfam PF13560 Helix-turn-helix domain 12 75 1.4E-6 T 14-10-2018 A4R43_10170 23630a6b8d849e80ba5e84c71734977f 361 SMART SM00530 12 77 3.1E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_09985 6f402a014ef3f6ff103d6aca21b88c9c 327 SUPERFAMILY SSF51430 1 317 1.83E-70 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_09985 6f402a014ef3f6ff103d6aca21b88c9c 327 Gene3D G3DSA:3.20.20.100 2 324 7.2E-73 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_09985 6f402a014ef3f6ff103d6aca21b88c9c 327 Pfam PF00248 Aldo/keto reductase family 16 314 9.3E-56 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_39300 0f6ce3304e4e05e8fb70ee2c934b85ad 205 Gene3D G3DSA:1.10.357.10 15 205 3.9E-44 T 14-10-2018 A4R43_39300 0f6ce3304e4e05e8fb70ee2c934b85ad 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.4E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_39300 0f6ce3304e4e05e8fb70ee2c934b85ad 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_39300 0f6ce3304e4e05e8fb70ee2c934b85ad 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_39300 0f6ce3304e4e05e8fb70ee2c934b85ad 205 SUPERFAMILY SSF46689 14 87 2.31E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_39300 0f6ce3304e4e05e8fb70ee2c934b85ad 205 SUPERFAMILY SSF48498 95 201 9.45E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 Gene3D G3DSA:3.40.50.970 1 178 8.1E-54 T 14-10-2018 A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 SUPERFAMILY SSF52467 156 357 9.04E-40 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 329 2.1E-24 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 SUPERFAMILY SSF52518 366 560 6.08E-52 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 5.9E-46 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 SUPERFAMILY SSF52518 4 185 3.25E-48 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 Gene3D G3DSA:3.40.50.1220 186 343 2.0E-39 T 14-10-2018 A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 544 1.6E-28 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4R43_15595 03940810b4144bb790b4e7c152573b8c 593 Gene3D G3DSA:3.40.50.970 357 585 1.1E-56 T 14-10-2018 A4R43_02690 27739d44b0bf5838e38e89fa7c6783a0 705 Gene3D G3DSA:3.40.50.880 415 684 3.7E-6 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_02690 27739d44b0bf5838e38e89fa7c6783a0 705 SUPERFAMILY SSF50934 81 232 6.67E-6 T 14-10-2018 IPR036813 Tachylectin 2 superfamily A4R43_02690 27739d44b0bf5838e38e89fa7c6783a0 705 Pfam PF14517 Tachylectin 36 215 3.1E-15 T 14-10-2018 IPR023294 Tachylectin 2 A4R43_02690 27739d44b0bf5838e38e89fa7c6783a0 705 SUPERFAMILY SSF52317 462 604 5.95E-5 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_02690 27739d44b0bf5838e38e89fa7c6783a0 705 Gene3D G3DSA:2.115.10.10 20 177 1.4E-28 T 14-10-2018 A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 Gene3D G3DSA:2.60.40.1180 604 665 1.1E-14 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 SUPERFAMILY SSF51445 5 362 3.28E-117 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 PIRSF PIRSF001084 1 665 2.2E-260 T 14-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 Pfam PF08533 Beta-galactosidase C-terminal domain 606 664 8.2E-7 T 14-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 Gene3D G3DSA:3.40.50.880 388 597 7.1E-69 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 Gene3D G3DSA:3.20.20.80 2 386 8.6E-135 T 14-10-2018 A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 SUPERFAMILY SSF52317 388 594 4.43E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 Pfam PF08532 Beta-galactosidase trimerisation domain 391 594 3.6E-62 T 14-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4R43_06760 b2ebff380a356cf5f61c2b0a5897ded9 666 Pfam PF02449 Beta-galactosidase 10 380 2.8E-146 T 14-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 SUPERFAMILY SSF52540 4 254 4.98E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 SUPERFAMILY SSF52540 292 533 5.77E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 SMART SM00382 33 240 1.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 SMART SM00382 322 511 2.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 Pfam PF00005 ABC transporter 25 183 7.7E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 ProSitePatterns PS00211 ABC transporters family signature. 434 448 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 Gene3D G3DSA:3.40.50.300 290 547 7.6E-79 T 14-10-2018 A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 Gene3D G3DSA:3.40.50.300 1 288 2.3E-84 T 14-10-2018 A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 Pfam PF00005 ABC transporter 314 462 6.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 267 0.039 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_08975 63094d1bb52f31ff9eb03a6aca94cd27 557 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 513 539 0.0096 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 447 466 1.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 427 435 1.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 373 384 1.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 Pfam PF00106 short chain dehydrogenase 304 487 6.6E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 Gene3D G3DSA:3.40.50.720 295 550 1.9E-69 T 14-10-2018 A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 SUPERFAMILY SSF51735 299 557 1.72E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 304 321 2.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 421 437 2.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 447 466 2.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 468 485 2.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 373 384 2.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 434 462 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 SUPERFAMILY SSF53474 4 275 2.23E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 Pfam PF00561 alpha/beta hydrolase fold 20 138 5.3E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_25645 7d3286767a4cf6391fc8b1b154f32acd 565 Gene3D G3DSA:3.40.50.1820 1 279 1.4E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13630 bbe31dfa03ddfd73f047d9b8ccbde441 317 Pfam PF00296 Luciferase-like monooxygenase 14 294 3.3E-52 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_13630 bbe31dfa03ddfd73f047d9b8ccbde441 317 SUPERFAMILY SSF51679 5 309 3.14E-53 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_13630 bbe31dfa03ddfd73f047d9b8ccbde441 317 TIGRFAM TIGR03841 F420_Rv3093c: probable F420-dependent oxidoreductase, Rv3093c family 11 301 4.2E-100 T 14-10-2018 IPR022526 F420-dependent oxidoreductase, Rv3093c A4R43_13630 bbe31dfa03ddfd73f047d9b8ccbde441 317 Gene3D G3DSA:3.20.20.30 4 316 9.1E-61 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_29545 cea769dff1f8f81837a611a5d507174e 424 Gene3D G3DSA:1.25.40.10 149 382 8.3E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_29545 cea769dff1f8f81837a611a5d507174e 424 Pfam PF13560 Helix-turn-helix domain 2 51 1.9E-7 T 14-10-2018 A4R43_29545 cea769dff1f8f81837a611a5d507174e 424 Gene3D G3DSA:1.10.260.40 1 51 5.3E-10 T 14-10-2018 A4R43_29545 cea769dff1f8f81837a611a5d507174e 424 SUPERFAMILY SSF47413 2 49 1.27E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_29545 cea769dff1f8f81837a611a5d507174e 424 SUPERFAMILY SSF48452 189 290 2.35E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05585 d81713afccc3f9d421ff8e28dee094b2 208 SUPERFAMILY SSF48498 71 203 1.05E-25 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_05585 d81713afccc3f9d421ff8e28dee094b2 208 Gene3D G3DSA:1.10.357.10 1 207 7.1E-51 T 14-10-2018 A4R43_05585 d81713afccc3f9d421ff8e28dee094b2 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 54 7.5E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05585 d81713afccc3f9d421ff8e28dee094b2 208 SUPERFAMILY SSF46689 1 63 3.54E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_05585 d81713afccc3f9d421ff8e28dee094b2 208 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 203 1.2E-16 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_10285 ad23d18b814746ffbb88ae94bfd154d1 422 Pfam PF13535 ATP-grasp domain 133 293 4.6E-13 T 14-10-2018 A4R43_10285 ad23d18b814746ffbb88ae94bfd154d1 422 Gene3D G3DSA:3.30.470.20 92 421 9.7E-30 T 14-10-2018 A4R43_10285 ad23d18b814746ffbb88ae94bfd154d1 422 SUPERFAMILY SSF56059 121 344 2.98E-29 T 14-10-2018 A4R43_10285 ad23d18b814746ffbb88ae94bfd154d1 422 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_30535 6e66f5bf2c8dacf476a789458b15a61e 176 ProSitePatterns PS00893 Nudix box signature. 64 85 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_30535 6e66f5bf2c8dacf476a789458b15a61e 176 PRINTS PR00502 NUDIX hydrolase family signature 59 73 1.4E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_30535 6e66f5bf2c8dacf476a789458b15a61e 176 PRINTS PR00502 NUDIX hydrolase family signature 73 88 1.4E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_30535 6e66f5bf2c8dacf476a789458b15a61e 176 SUPERFAMILY SSF55811 30 162 5.01E-33 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_30535 6e66f5bf2c8dacf476a789458b15a61e 176 Pfam PF00293 NUDIX domain 32 155 3.4E-23 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_30535 6e66f5bf2c8dacf476a789458b15a61e 176 Gene3D G3DSA:3.90.79.10 23 166 1.4E-35 T 14-10-2018 A4R43_37560 35815dd4c18717e2eba52a15950fbb78 355 Pfam PF07728 AAA domain (dynein-related subfamily) 75 216 1.8E-32 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A4R43_37560 35815dd4c18717e2eba52a15950fbb78 355 SMART SM00382 71 226 0.0057 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_37560 35815dd4c18717e2eba52a15950fbb78 355 Gene3D G3DSA:3.40.50.300 55 235 6.5E-24 T 14-10-2018 A4R43_37560 35815dd4c18717e2eba52a15950fbb78 355 SUPERFAMILY SSF52540 54 312 6.9E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 SMART SM00322 59 124 4.1E-7 T 14-10-2018 IPR004087 K Homology domain GO:0003676 A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.1E-92 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 Gene3D G3DSA:3.30.300.20 17 106 6.4E-32 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 37.694 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 7.3E-35 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 Pfam PF07650 KH domain 37 109 8.0E-19 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 SUPERFAMILY SSF54821 106 206 1.7E-35 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 Gene3D G3DSA:3.30.1140.32 107 208 7.8E-38 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 SUPERFAMILY SSF54814 2 105 1.2E-36 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4R43_33870 d9e80673755e2f6f1e6ada9766f9f2c6 286 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_32155 ac533539270afaf59090c42caf7ec1dc 201 Gene3D G3DSA:1.10.10.60 1 49 3.2E-20 T 14-10-2018 A4R43_32155 ac533539270afaf59090c42caf7ec1dc 201 Gene3D G3DSA:1.10.357.10 51 189 1.0E-16 T 14-10-2018 A4R43_32155 ac533539270afaf59090c42caf7ec1dc 201 SUPERFAMILY SSF46689 4 69 7.56E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_32155 ac533539270afaf59090c42caf7ec1dc 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_32155 ac533539270afaf59090c42caf7ec1dc 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32155 ac533539270afaf59090c42caf7ec1dc 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32155 ac533539270afaf59090c42caf7ec1dc 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 2.0E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05725 3bc295edfaf41171d881708b26258495 397 Gene3D G3DSA:2.60.110.10 40 369 3.7E-108 T 14-10-2018 IPR037176 Osmotin/thaumatin-like superfamily A4R43_05725 3bc295edfaf41171d881708b26258495 397 Pfam PF16483 Beta-1,3-glucanase 33 392 5.9E-120 T 14-10-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 A4R43_05725 3bc295edfaf41171d881708b26258495 397 Gene3D G3DSA:3.30.920.50 234 344 3.7E-108 T 14-10-2018 A4R43_00320 29ec742b6f29e889f944ef3d07e0ac3a 392 Gene3D G3DSA:3.30.1540.10 228 319 8.4E-130 T 14-10-2018 A4R43_00320 29ec742b6f29e889f944ef3d07e0ac3a 392 SUPERFAMILY SSF89796 2 392 1.57E-129 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_00320 29ec742b6f29e889f944ef3d07e0ac3a 392 Gene3D G3DSA:3.40.50.10540 4 386 8.4E-130 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_00320 29ec742b6f29e889f944ef3d07e0ac3a 392 Pfam PF02515 CoA-transferase family III 5 368 1.7E-120 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_17175 21604f8df5d8a460cfef3fcb8a1c63c3 396 Pfam PF07690 Major Facilitator Superfamily 10 311 2.6E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_17175 21604f8df5d8a460cfef3fcb8a1c63c3 396 Gene3D G3DSA:1.20.1250.20 1 381 1.2E-29 T 14-10-2018 A4R43_17175 21604f8df5d8a460cfef3fcb8a1c63c3 396 SUPERFAMILY SSF103473 3 380 2.88E-33 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_17175 21604f8df5d8a460cfef3fcb8a1c63c3 396 PRINTS PR01988 Putative bacilysin exporter bacE signature 92 110 5.8E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_17175 21604f8df5d8a460cfef3fcb8a1c63c3 396 PRINTS PR01988 Putative bacilysin exporter bacE signature 162 179 5.8E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_17175 21604f8df5d8a460cfef3fcb8a1c63c3 396 PRINTS PR01988 Putative bacilysin exporter bacE signature 247 264 5.8E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_17175 21604f8df5d8a460cfef3fcb8a1c63c3 396 PRINTS PR01988 Putative bacilysin exporter bacE signature 353 376 5.8E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_17175 21604f8df5d8a460cfef3fcb8a1c63c3 396 PRINTS PR01988 Putative bacilysin exporter bacE signature 7 29 5.8E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_33965 59a2f5a148cd3ace12824442893e87d0 73 SUPERFAMILY SSF50249 4 72 4.5E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_33965 59a2f5a148cd3ace12824442893e87d0 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 4.0E-38 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A4R43_33965 59a2f5a148cd3ace12824442893e87d0 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.538 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A4R43_33965 59a2f5a148cd3ace12824442893e87d0 73 Gene3D G3DSA:2.40.50.140 1 73 1.4E-38 T 14-10-2018 A4R43_33965 59a2f5a148cd3ace12824442893e87d0 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 1.8E-29 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A4R43_29020 f9922066bb65573a43a28f107aee9b9b 477 Gene3D G3DSA:3.40.605.10 27 462 1.4E-143 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_29020 f9922066bb65573a43a28f107aee9b9b 477 Gene3D G3DSA:3.40.309.10 255 443 1.4E-143 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_29020 f9922066bb65573a43a28f107aee9b9b 477 SUPERFAMILY SSF53720 6 476 6.94E-136 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_29020 f9922066bb65573a43a28f107aee9b9b 477 Pfam PF00171 Aldehyde dehydrogenase family 13 471 1.6E-136 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_26285 9e9165a11a263705f679fadb9d49a103 166 SUPERFAMILY SSF55729 8 126 2.57E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_26285 9e9165a11a263705f679fadb9d49a103 166 Gene3D G3DSA:3.40.630.30 5 166 5.6E-52 T 14-10-2018 A4R43_26285 9e9165a11a263705f679fadb9d49a103 166 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 7 164 2.8E-58 T 14-10-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00260+2.3.1.178 A4R43_26285 9e9165a11a263705f679fadb9d49a103 166 Pfam PF00583 Acetyltransferase (GNAT) family 36 126 6.2E-15 T 14-10-2018 IPR000182 GNAT domain A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 SUPERFAMILY SSF52402 12 156 7.79E-30 T 14-10-2018 A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 PRINTS PR01438 Universal stress protein signature 260 272 3.4E-15 T 14-10-2018 IPR006015 Universal stress protein A A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 PRINTS PR01438 Universal stress protein signature 161 179 3.4E-15 T 14-10-2018 IPR006015 Universal stress protein A A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 PRINTS PR01438 Universal stress protein signature 278 300 3.4E-15 T 14-10-2018 IPR006015 Universal stress protein A A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 Pfam PF00582 Universal stress protein family 12 153 2.1E-24 T 14-10-2018 IPR006016 UspA A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 Pfam PF00582 Universal stress protein family 164 300 8.7E-26 T 14-10-2018 IPR006016 UspA A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 SUPERFAMILY SSF52402 163 301 7.2E-32 T 14-10-2018 A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 Gene3D G3DSA:3.40.50.620 158 302 3.8E-42 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_01470 f21230cb62d0965ed49514a3943d0a37 302 Gene3D G3DSA:3.40.50.620 3 157 5.1E-32 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_22730 3bba71c4dfa077b897fcc37a7790f123 31 Pfam PF08042 PqqA family 9 26 6.8E-8 T 14-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 A4R43_22730 3bba71c4dfa077b897fcc37a7790f123 31 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 9 28 2.3E-7 T 14-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 A4R43_33895 99e1b334de7a13f4a8a069be004a1714 104 SMART SM00739 2 29 1.6E-5 T 14-10-2018 IPR005824 KOW A4R43_33895 99e1b334de7a13f4a8a069be004a1714 104 Pfam PF00467 KOW motif 5 36 2.0E-9 T 14-10-2018 IPR005824 KOW A4R43_33895 99e1b334de7a13f4a8a069be004a1714 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 104 1.4E-37 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33895 99e1b334de7a13f4a8a069be004a1714 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 104 1.8E-26 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33895 99e1b334de7a13f4a8a069be004a1714 104 Gene3D G3DSA:2.30.30.30 1 104 3.9E-36 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 A4R43_33895 99e1b334de7a13f4a8a069be004a1714 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 98 21.946 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33895 99e1b334de7a13f4a8a069be004a1714 104 SUPERFAMILY SSF50104 2 101 7.9E-32 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4R43_33895 99e1b334de7a13f4a8a069be004a1714 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 14-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_26185 88eed3ea173fd77e88cbb86f3a87de84 221 SUPERFAMILY SSF51391 11 218 5.75E-61 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4R43_26185 88eed3ea173fd77e88cbb86f3a87de84 221 Pfam PF02581 Thiamine monophosphate synthase 18 203 2.0E-52 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4R43_26185 88eed3ea173fd77e88cbb86f3a87de84 221 Gene3D G3DSA:3.20.20.70 8 221 4.5E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_26185 88eed3ea173fd77e88cbb86f3a87de84 221 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 17 216 4.0E-61 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4R43_26185 88eed3ea173fd77e88cbb86f3a87de84 221 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 16 221 25.436 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 464 7.5E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 Gene3D G3DSA:3.30.565.10 316 467 7.4E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 311 1.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 Gene3D G3DSA:1.10.287.130 194 313 1.5E-22 T 14-10-2018 A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 SUPERFAMILY SSF55874 302 464 5.24E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 SUPERFAMILY SSF47384 232 311 2.55E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 SMART SM00304 190 247 6.2E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 SMART SM00388 248 312 1.4E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 SMART SM00387 356 466 2.1E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 8.4E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 8.4E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_16895 27b94f5aa8eae78b84c91f9c95f74147 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 8.4E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 Pfam PF03466 LysR substrate binding domain 88 272 1.8E-24 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 SUPERFAMILY SSF53850 87 271 4.65E-24 T 14-10-2018 A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 Gene3D G3DSA:1.10.10.10 1 85 3.1E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 SUPERFAMILY SSF46785 1 83 2.95E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 Gene3D G3DSA:3.40.190.10 90 271 4.1E-25 T 14-10-2018 A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.0E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_40600 b7f8b69b7b00f4c034a71c5ded0fca77 278 Gene3D G3DSA:3.40.190.10 158 253 4.1E-25 T 14-10-2018 A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 Gene3D G3DSA:3.40.50.720 3 255 9.1E-90 T 14-10-2018 A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 SUPERFAMILY SSF51735 6 247 4.86E-81 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 7.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19165 9b93e0150e301a3fb9b7b0a660b452f5 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 248 2.9E-72 T 14-10-2018 A4R43_05840 c1438b5eff35da0ed70648b7427dba3f 512 Gene3D G3DSA:3.40.605.10 48 485 2.6E-75 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_05840 c1438b5eff35da0ed70648b7427dba3f 512 SUPERFAMILY SSF53720 37 490 2.88E-74 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_05840 c1438b5eff35da0ed70648b7427dba3f 512 Pfam PF00171 Aldehyde dehydrogenase family 47 488 3.3E-88 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_05840 c1438b5eff35da0ed70648b7427dba3f 512 Gene3D G3DSA:3.40.309.10 262 466 2.6E-75 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_27125 0c0f558d7e7cf3694ede644191904eaa 500 Pfam PF00854 POT family 106 465 2.1E-56 T 14-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 A4R43_27125 0c0f558d7e7cf3694ede644191904eaa 500 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 25 496 2.8E-144 T 14-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 A4R43_27125 0c0f558d7e7cf3694ede644191904eaa 500 Gene3D G3DSA:1.20.1250.20 14 500 1.8E-128 T 14-10-2018 A4R43_27125 0c0f558d7e7cf3694ede644191904eaa 500 SUPERFAMILY SSF103473 29 489 9.59E-28 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_20855 d9f4bd1cfe4725593fc94cb8fe28eed8 157 Gene3D G3DSA:1.10.10.10 105 157 1.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20855 d9f4bd1cfe4725593fc94cb8fe28eed8 157 Gene3D G3DSA:1.10.1740.10 9 99 4.9E-12 T 14-10-2018 A4R43_20855 d9f4bd1cfe4725593fc94cb8fe28eed8 157 Pfam PF04542 Sigma-70 region 2 33 95 1.9E-8 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_20855 d9f4bd1cfe4725593fc94cb8fe28eed8 157 SUPERFAMILY SSF88946 14 94 2.67E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_20855 d9f4bd1cfe4725593fc94cb8fe28eed8 157 Pfam PF04545 Sigma-70, region 4 110 156 1.9E-12 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_20855 d9f4bd1cfe4725593fc94cb8fe28eed8 157 SUPERFAMILY SSF88659 106 156 5.42E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_24230 6d542534413d9318d1fb2ba889e44dae 148 Pfam PF12833 Helix-turn-helix domain 38 116 2.5E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_24230 6d542534413d9318d1fb2ba889e44dae 148 SMART SM00342 32 115 5.1E-32 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_24230 6d542534413d9318d1fb2ba889e44dae 148 SUPERFAMILY SSF46689 68 119 7.17E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_24230 6d542534413d9318d1fb2ba889e44dae 148 SUPERFAMILY SSF46689 16 66 3.27E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_24230 6d542534413d9318d1fb2ba889e44dae 148 Gene3D G3DSA:1.10.10.60 12 122 4.5E-28 T 14-10-2018 A4R43_17555 2bb8f996530165a859ea528818220490 525 Gene3D G3DSA:3.90.700.10 230 332 2.9E-132 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_17555 2bb8f996530165a859ea528818220490 525 SUPERFAMILY SSF56425 220 337 3.59E-32 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_17555 2bb8f996530165a859ea528818220490 525 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 1 493 1.0E-156 T 14-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4R43_17555 2bb8f996530165a859ea528818220490 525 SUPERFAMILY SSF46977 419 511 2.09E-19 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_17555 2bb8f996530165a859ea528818220490 525 Gene3D G3DSA:3.50.50.60 1 387 2.9E-132 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17555 2bb8f996530165a859ea528818220490 525 Gene3D G3DSA:1.20.58.100 408 508 8.2E-13 T 14-10-2018 A4R43_17555 2bb8f996530165a859ea528818220490 525 SUPERFAMILY SSF51905 1 397 1.61E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17555 2bb8f996530165a859ea528818220490 525 Pfam PF00890 FAD binding domain 1 377 3.3E-81 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_17555 2bb8f996530165a859ea528818220490 525 Pfam PF02910 Fumarate reductase flavoprotein C-term 421 507 1.6E-8 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_15435 901ea2bf5ead7aadcdc4cbdac9d56069 384 Gene3D G3DSA:1.20.1250.20 198 379 1.3E-17 T 14-10-2018 A4R43_15435 901ea2bf5ead7aadcdc4cbdac9d56069 384 Pfam PF07690 Major Facilitator Superfamily 9 246 1.3E-30 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_15435 901ea2bf5ead7aadcdc4cbdac9d56069 384 Gene3D G3DSA:1.20.1250.20 3 197 7.4E-26 T 14-10-2018 A4R43_15435 901ea2bf5ead7aadcdc4cbdac9d56069 384 SUPERFAMILY SSF103473 3 377 3.79E-55 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_20525 6560ad8350320c0798b3ed047d32d510 166 Gene3D G3DSA:1.20.1290.10 20 165 2.7E-40 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_20525 6560ad8350320c0798b3ed047d32d510 166 SUPERFAMILY SSF69118 33 163 4.71E-35 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_20525 6560ad8350320c0798b3ed047d32d510 166 Pfam PF02627 Carboxymuconolactone decarboxylase family 40 112 4.9E-16 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_20525 6560ad8350320c0798b3ed047d32d510 166 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 48 94 8.7E-15 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_36675 9934bc42e770e5d1f759a301ec990b5b 310 SUPERFAMILY SSF56563 7 308 8.63E-19 T 14-10-2018 A4R43_36675 9934bc42e770e5d1f759a301ec990b5b 310 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 11 296 4.8E-13 T 14-10-2018 IPR024455 Phage capsid A4R43_36675 9934bc42e770e5d1f759a301ec990b5b 310 Pfam PF05065 Phage capsid family 12 305 4.6E-12 T 14-10-2018 IPR024455 Phage capsid A4R43_03915 4158cab9c9a4521f568f18390c57dd73 195 Pfam PF01227 GTP cyclohydrolase I 20 191 8.7E-64 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_03915 4158cab9c9a4521f568f18390c57dd73 195 Gene3D G3DSA:1.10.286.10 9 55 5.4E-11 T 14-10-2018 A4R43_03915 4158cab9c9a4521f568f18390c57dd73 195 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 15 193 34.692 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_03915 4158cab9c9a4521f568f18390c57dd73 195 Gene3D G3DSA:3.30.1130.10 61 193 6.2E-56 T 14-10-2018 A4R43_03915 4158cab9c9a4521f568f18390c57dd73 195 SUPERFAMILY SSF55620 8 192 7.19E-69 T 14-10-2018 A4R43_03915 4158cab9c9a4521f568f18390c57dd73 195 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 21 189 3.1E-58 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 SUPERFAMILY SSF55347 151 312 3.57E-71 T 14-10-2018 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 Gene3D G3DSA:3.30.360.10 151 314 4.8E-149 T 14-10-2018 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 SUPERFAMILY SSF51735 3 168 1.22E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.8E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 1.8E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 1.8E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.8E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.8E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 SMART SM00846 3 152 4.8E-90 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 PIRSF PIRSF000149 1 332 1.2E-129 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 312 4.0E-67 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 Gene3D G3DSA:3.40.50.720 4 326 4.8E-149 T 14-10-2018 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 1.1E-36 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04915 5dcfcfcc41fc37a3071abb1516020fc4 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 2.9E-134 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 Pfam PF13855 Leucine rich repeat 154 194 4.5E-7 T 14-10-2018 IPR001611 Leucine-rich repeat GO:0005515 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 Pfam PF13855 Leucine rich repeat 100 149 5.6E-9 T 14-10-2018 IPR001611 Leucine-rich repeat GO:0005515 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 Gene3D G3DSA:3.80.10.10 1 213 2.6E-60 T 14-10-2018 IPR032675 Leucine-rich repeat domain superfamily A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 Pfam PF12799 Leucine Rich repeats (2 copies) 44 84 6.9E-8 T 14-10-2018 IPR025875 Leucine rich repeat 4 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00369 21 41 380.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00369 66 89 0.64 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00369 113 135 0.14 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00369 136 158 0.25 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00369 90 112 28.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00369 159 182 0.034 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00369 43 65 0.95 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SUPERFAMILY SSF52058 3 202 1.05E-47 T 14-10-2018 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00364 136 155 8.7 T 14-10-2018 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00364 20 39 130.0 T 14-10-2018 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00364 159 178 190.0 T 14-10-2018 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00364 90 109 6.0 T 14-10-2018 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00364 113 132 24.0 T 14-10-2018 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00364 67 86 5.4 T 14-10-2018 A4R43_31210 0851ab61e5ea86e6de495c2e4122d0fb 214 SMART SM00364 43 62 310.0 T 14-10-2018 A4R43_12700 00bb94fb66535fa0dcfb34ebc1ac277f 354 Gene3D G3DSA:3.40.50.1000 9 150 6.8E-31 T 14-10-2018 IPR023214 HAD superfamily A4R43_12700 00bb94fb66535fa0dcfb34ebc1ac277f 354 Gene3D G3DSA:3.40.630.30 183 303 4.9E-5 T 14-10-2018 A4R43_12700 00bb94fb66535fa0dcfb34ebc1ac277f 354 SUPERFAMILY SSF55729 159 317 3.63E-5 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_12700 00bb94fb66535fa0dcfb34ebc1ac277f 354 TIGRFAM TIGR01686 FkbH: FkbH domain 9 316 3.4E-63 T 14-10-2018 IPR010037 FkbH domain A4R43_12700 00bb94fb66535fa0dcfb34ebc1ac277f 354 SUPERFAMILY SSF56784 7 112 8.27E-16 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_04860 9cec0b65c9188d11b2e96af986c2205c 328 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 28.685 T 14-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 A4R43_04860 9cec0b65c9188d11b2e96af986c2205c 328 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 2.0E-24 T 14-10-2018 IPR039518 WhiA, LAGLIDADG-like domain A4R43_04860 9cec0b65c9188d11b2e96af986c2205c 328 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 1.3E-102 T 14-10-2018 IPR033981 Sporulation regulator WhiA-like A4R43_04860 9cec0b65c9188d11b2e96af986c2205c 328 Gene3D G3DSA:1.10.10.10 216 307 3.5E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04860 9cec0b65c9188d11b2e96af986c2205c 328 Pfam PF02650 WhiA C-terminal HTH domain 221 303 1.7E-18 T 14-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal A4R43_04860 9cec0b65c9188d11b2e96af986c2205c 328 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 22 104 1.2E-23 T 14-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain A4R43_04860 9cec0b65c9188d11b2e96af986c2205c 328 Gene3D G3DSA:3.10.28.10 1 214 4.1E-18 T 14-10-2018 IPR027434 Homing endonuclease A4R43_17315 0fa119f8cb54415e2467b8514650c46c 287 SUPERFAMILY SSF52540 4 231 2.38E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17315 0fa119f8cb54415e2467b8514650c46c 287 SMART SM00382 33 215 1.6E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_17315 0fa119f8cb54415e2467b8514650c46c 287 Pfam PF00005 ABC transporter 25 166 2.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_17315 0fa119f8cb54415e2467b8514650c46c 287 Gene3D G3DSA:3.40.50.300 2 280 6.2E-71 T 14-10-2018 A4R43_17315 0fa119f8cb54415e2467b8514650c46c 287 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_37670 7c5426d9a5f013f8d307a13885d3e822 352 Gene3D G3DSA:1.10.101.10 108 171 2.0E-5 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_37670 7c5426d9a5f013f8d307a13885d3e822 352 SUPERFAMILY SSF47090 119 171 1.2E-6 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_37670 7c5426d9a5f013f8d307a13885d3e822 352 Pfam PF01471 Putative peptidoglycan binding domain 120 170 1.0E-4 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_37670 7c5426d9a5f013f8d307a13885d3e822 352 Gene3D G3DSA:2.40.30.170 210 288 1.3E-13 T 14-10-2018 A4R43_37670 7c5426d9a5f013f8d307a13885d3e822 352 Pfam PF13437 HlyD family secretion protein 176 270 2.4E-7 T 14-10-2018 A4R43_37670 7c5426d9a5f013f8d307a13885d3e822 352 Gene3D G3DSA:2.40.50.100 179 209 1.3E-13 T 14-10-2018 A4R43_37670 7c5426d9a5f013f8d307a13885d3e822 352 Gene3D G3DSA:2.40.420.20 289 348 1.3E-13 T 14-10-2018 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 PRINTS PR01466 Bacterial arginine deiminase signature 373 391 8.2E-39 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 PRINTS PR01466 Bacterial arginine deiminase signature 350 364 8.2E-39 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 PRINTS PR01466 Bacterial arginine deiminase signature 145 163 8.2E-39 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 PRINTS PR01466 Bacterial arginine deiminase signature 173 188 8.2E-39 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 PRINTS PR01466 Bacterial arginine deiminase signature 330 347 8.2E-39 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 Hamap MF_00242 Arginine deiminase [arcA]. 1 394 40.76 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 PIRSF PIRSF006356 1 394 1.2E-134 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 Gene3D G3DSA:3.75.10.10 1 391 1.2E-141 T 14-10-2018 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 Pfam PF02274 Amidinotransferase 13 391 4.5E-96 T 14-10-2018 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 SUPERFAMILY SSF55909 1 393 1.57E-114 T 14-10-2018 A4R43_28580 10c167e32bbb08626471f9fd62da1e11 395 Gene3D G3DSA:1.10.3930.10 63 144 1.2E-141 T 14-10-2018 A4R43_16540 fa04e849d953f7b613ea22187aba74c6 261 Pfam PF06966 Protein of unknown function (DUF1295) 22 243 8.2E-69 T 14-10-2018 IPR010721 Protein of unknown function DUF1295 A4R43_16540 fa04e849d953f7b613ea22187aba74c6 261 Gene3D G3DSA:1.20.120.1630 55 249 6.0E-9 T 14-10-2018 A4R43_11665 0f04b0468a2cf51340c184e5afe1efa3 401 Pfam PF07730 Histidine kinase 197 261 1.5E-17 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_11665 0f04b0468a2cf51340c184e5afe1efa3 401 SUPERFAMILY SSF55874 280 394 2.44E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_11665 0f04b0468a2cf51340c184e5afe1efa3 401 Gene3D G3DSA:3.30.565.10 271 396 2.2E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_02255 76e9c131c1dcbbd6ba7e9594a7693bb2 161 Gene3D G3DSA:3.10.180.10 2 152 1.5E-15 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_02255 76e9c131c1dcbbd6ba7e9594a7693bb2 161 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 144 5.1E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_02255 76e9c131c1dcbbd6ba7e9594a7693bb2 161 SUPERFAMILY SSF54593 4 149 1.14E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_26625 d9683e54f397b5f87af44d56545def3b 284 PIRSF PIRSF000103 1 284 6.8E-21 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_26625 d9683e54f397b5f87af44d56545def3b 284 Gene3D G3DSA:3.40.50.720 2 153 1.0E-24 T 14-10-2018 A4R43_26625 d9683e54f397b5f87af44d56545def3b 284 SUPERFAMILY SSF51735 5 148 2.79E-17 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_26625 d9683e54f397b5f87af44d56545def3b 284 Gene3D G3DSA:1.10.1040.10 155 284 5.1E-34 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_26625 d9683e54f397b5f87af44d56545def3b 284 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 146 8.0E-8 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 Pfam PF01261 Xylose isomerase-like TIM barrel 42 265 1.5E-23 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 SUPERFAMILY SSF51658 6 387 8.43E-108 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 Hamap MF_00455 Xylose isomerase [xylA]. 1 385 33.018 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 45 67 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 178 202 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 281 292 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 220 247 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 248 259 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 129 150 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 156 175 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 82 102 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 PRINTS PR00688 Xylose isomerase signature 105 124 1.9E-60 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 Gene3D G3DSA:3.20.20.150 3 389 4.2E-130 T 14-10-2018 A4R43_40700 154a85b4bd2c677a1ca10becc7c7d54b 389 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 5 385 6.8E-196 T 14-10-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4R43_08575 9f48929bba4e63e33910cf99e3187790 218 SMART SM01110 32 202 0.0012 T 14-10-2018 IPR000675 Cutinase/acetylxylan esterase GO:0016787 A4R43_08575 9f48929bba4e63e33910cf99e3187790 218 Gene3D G3DSA:3.40.50.1820 2 208 1.0E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08575 9f48929bba4e63e33910cf99e3187790 218 SUPERFAMILY SSF53474 33 191 1.81E-14 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08575 9f48929bba4e63e33910cf99e3187790 218 Pfam PF01083 Cutinase 60 181 2.7E-8 T 14-10-2018 IPR000675 Cutinase/acetylxylan esterase GO:0016787 A4R43_12600 09aafa3ade66d4d9ca43f42d730c0216 869 Gene3D G3DSA:1.10.510.10 312 428 7.9E-21 T 14-10-2018 A4R43_12600 09aafa3ade66d4d9ca43f42d730c0216 869 SMART SM00220 225 485 3.5E-5 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_12600 09aafa3ade66d4d9ca43f42d730c0216 869 Pfam PF00069 Protein kinase domain 236 406 7.1E-9 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_12600 09aafa3ade66d4d9ca43f42d730c0216 869 SUPERFAMILY SSF158745 532 840 3.27E-20 T 14-10-2018 A4R43_12600 09aafa3ade66d4d9ca43f42d730c0216 869 SUPERFAMILY SSF56112 225 421 4.18E-23 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_12600 09aafa3ade66d4d9ca43f42d730c0216 869 SMART SM01260 529 849 7.8E-5 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_12600 09aafa3ade66d4d9ca43f42d730c0216 869 Gene3D G3DSA:1.50.10.10 630 811 3.3E-6 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_12600 09aafa3ade66d4d9ca43f42d730c0216 869 Gene3D G3DSA:3.30.200.20 224 311 7.9E-21 T 14-10-2018 A4R43_22805 517593be62a8067c000610d2e60e5ef6 487 SUPERFAMILY SSF53720 15 486 7.59E-162 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_22805 517593be62a8067c000610d2e60e5ef6 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_22805 517593be62a8067c000610d2e60e5ef6 487 Gene3D G3DSA:3.40.309.10 265 454 3.8E-169 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_22805 517593be62a8067c000610d2e60e5ef6 487 Pfam PF00171 Aldehyde dehydrogenase family 23 482 6.5E-160 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_22805 517593be62a8067c000610d2e60e5ef6 487 Gene3D G3DSA:3.40.605.10 31 478 3.8E-169 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_20365 2879c574a284b4a7d70fd5a18772b203 272 Pfam PF06445 GyrI-like small molecule binding domain 136 270 4.3E-9 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain A4R43_20365 2879c574a284b4a7d70fd5a18772b203 272 Pfam PF13411 MerR HTH family regulatory protein 3 69 1.0E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20365 2879c574a284b4a7d70fd5a18772b203 272 Gene3D G3DSA:1.10.1660.10 1 124 8.6E-27 T 14-10-2018 A4R43_20365 2879c574a284b4a7d70fd5a18772b203 272 SMART SM00422 2 72 1.0E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_20365 2879c574a284b4a7d70fd5a18772b203 272 SMART SM00871 119 271 4.1E-10 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding A4R43_20365 2879c574a284b4a7d70fd5a18772b203 272 SUPERFAMILY SSF46955 2 117 1.1E-24 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_20365 2879c574a284b4a7d70fd5a18772b203 272 SUPERFAMILY SSF55136 124 271 1.02E-13 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A4R43_20365 2879c574a284b4a7d70fd5a18772b203 272 Gene3D G3DSA:3.20.80.10 125 271 1.5E-22 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A4R43_06680 7f22a4a60d7e822f7a73f738afd27b1b 134 SUPERFAMILY SSF54593 3 129 1.39E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_06680 7f22a4a60d7e822f7a73f738afd27b1b 134 Gene3D G3DSA:3.10.180.10 9 134 1.2E-39 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_06680 7f22a4a60d7e822f7a73f738afd27b1b 134 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 128 8.3E-12 T 14-10-2018 IPR028973 PhnB-like A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 SUPERFAMILY SSF50249 13 152 5.88E-37 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 20 500 35.319 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 SUPERFAMILY SSF55681 160 498 7.66E-101 T 14-10-2018 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 Pfam PF01336 OB-fold nucleic acid binding domain 68 142 9.3E-10 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 383 399 1.2E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 241 254 1.2E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 196 206 1.2E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 259 276 1.2E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 212 228 1.2E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 Pfam PF00152 tRNA synthetases class II (D, K and N) 160 497 1.2E-68 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 15 499 7.6E-143 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 Gene3D G3DSA:3.30.930.10 158 500 5.2E-113 T 14-10-2018 A4R43_26760 725989e676fcabd8be71bdce4b2a357d 500 Gene3D G3DSA:2.40.50.140 15 152 2.0E-39 T 14-10-2018 A4R43_03710 1ef37a9217c65ecace87795ef99a76ef 535 Pfam PF00005 ABC transporter 24 171 1.4E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_03710 1ef37a9217c65ecace87795ef99a76ef 535 SUPERFAMILY SSF52540 347 530 4.79E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_03710 1ef37a9217c65ecace87795ef99a76ef 535 SUPERFAMILY SSF52540 9 220 4.02E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_03710 1ef37a9217c65ecace87795ef99a76ef 535 Gene3D G3DSA:3.40.50.300 3 267 1.5E-57 T 14-10-2018 A4R43_03710 1ef37a9217c65ecace87795ef99a76ef 535 SMART SM00382 363 531 7.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03710 1ef37a9217c65ecace87795ef99a76ef 535 SMART SM00382 30 215 1.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03710 1ef37a9217c65ecace87795ef99a76ef 535 Pfam PF00005 ABC transporter 355 485 2.6E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_03710 1ef37a9217c65ecace87795ef99a76ef 535 Gene3D G3DSA:3.40.50.300 309 534 2.2E-39 T 14-10-2018 A4R43_37330 c83f0f469e9b1d665427ab300226bb90 67 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 6 65 3.3E-14 T 14-10-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit A4R43_38610 5f8ffa829d3bda9343518d899d99d1eb 170 SUPERFAMILY SSF46785 19 152 1.06E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38610 5f8ffa829d3bda9343518d899d99d1eb 170 Pfam PF01047 MarR family 47 104 3.6E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38610 5f8ffa829d3bda9343518d899d99d1eb 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_38610 5f8ffa829d3bda9343518d899d99d1eb 170 SMART SM00347 40 140 4.5E-19 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38610 5f8ffa829d3bda9343518d899d99d1eb 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 1.6E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38610 5f8ffa829d3bda9343518d899d99d1eb 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 1.6E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38610 5f8ffa829d3bda9343518d899d99d1eb 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 1.6E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38610 5f8ffa829d3bda9343518d899d99d1eb 170 Gene3D G3DSA:1.10.10.10 10 155 4.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11150 6b25c69ef9f03c76638bc946cfabf067 423 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 74 350 2.8E-46 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_11150 6b25c69ef9f03c76638bc946cfabf067 423 SUPERFAMILY SSF55931 34 354 6.18E-33 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_11150 6b25c69ef9f03c76638bc946cfabf067 423 PIRSF PIRSF017901 3 422 1.3E-85 T 14-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_11150 6b25c69ef9f03c76638bc946cfabf067 423 Gene3D G3DSA:3.30.590.20 16 421 7.3E-86 T 14-10-2018 A4R43_11150 6b25c69ef9f03c76638bc946cfabf067 423 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 18 415 29.898 T 14-10-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_23405 7f5b1bb4d7cf9814e4a43bba0caadfe0 337 SMART SM00382 27 210 1.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_23405 7f5b1bb4d7cf9814e4a43bba0caadfe0 337 Pfam PF00005 ABC transporter 19 160 4.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23405 7f5b1bb4d7cf9814e4a43bba0caadfe0 337 SUPERFAMILY SSF52540 3 238 4.11E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23405 7f5b1bb4d7cf9814e4a43bba0caadfe0 337 Gene3D G3DSA:3.40.50.300 1 236 8.3E-74 T 14-10-2018 A4R43_23405 7f5b1bb4d7cf9814e4a43bba0caadfe0 337 SUPERFAMILY SSF50331 253 332 5.67E-7 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_23405 7f5b1bb4d7cf9814e4a43bba0caadfe0 337 Pfam PF08402 TOBE domain 265 332 4.0E-10 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A4R43_23405 7f5b1bb4d7cf9814e4a43bba0caadfe0 337 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_36545 ba4e63ed5b4e6146725c2f80383d69ce 132 SUPERFAMILY SSF46955 1 112 5.49E-26 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_36545 ba4e63ed5b4e6146725c2f80383d69ce 132 Gene3D G3DSA:1.10.1660.10 1 126 5.3E-31 T 14-10-2018 A4R43_36545 ba4e63ed5b4e6146725c2f80383d69ce 132 Pfam PF13411 MerR HTH family regulatory protein 1 61 5.1E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36545 ba4e63ed5b4e6146725c2f80383d69ce 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36545 ba4e63ed5b4e6146725c2f80383d69ce 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.4E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36545 ba4e63ed5b4e6146725c2f80383d69ce 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36545 ba4e63ed5b4e6146725c2f80383d69ce 132 SMART SM00422 1 69 2.3E-22 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_34685 c5307eb96e686637f8ee3412364271e6 472 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 404 414 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_34685 c5307eb96e686637f8ee3412364271e6 472 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 164 175 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_34685 c5307eb96e686637f8ee3412364271e6 472 Pfam PF00082 Subtilase family 161 450 1.8E-40 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_34685 c5307eb96e686637f8ee3412364271e6 472 SUPERFAMILY SSF52743 140 471 3.01E-64 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_34685 c5307eb96e686637f8ee3412364271e6 472 PRINTS PR00723 Subtilisin serine protease family (S8) signature 159 178 4.6E-17 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_34685 c5307eb96e686637f8ee3412364271e6 472 PRINTS PR00723 Subtilisin serine protease family (S8) signature 403 419 4.6E-17 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_34685 c5307eb96e686637f8ee3412364271e6 472 PRINTS PR00723 Subtilisin serine protease family (S8) signature 205 218 4.6E-17 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_34685 c5307eb96e686637f8ee3412364271e6 472 Gene3D G3DSA:3.40.50.200 125 472 6.4E-73 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_41145 7eb50302733913b7f140a273dfafd024 170 Gene3D G3DSA:3.90.1140.10 1 168 2.3E-31 T 14-10-2018 A4R43_41145 7eb50302733913b7f140a273dfafd024 170 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 2 153 1.1E-21 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A4R43_41145 7eb50302733913b7f140a273dfafd024 170 SUPERFAMILY SSF55144 3 159 4.71E-26 T 14-10-2018 IPR009097 Cyclic phosphodiesterase A4R43_41145 7eb50302733913b7f140a273dfafd024 170 Pfam PF02834 LigT like Phosphoesterase 11 77 2.1E-9 T 14-10-2018 IPR014051 Phosphoesterase, HXTX A4R43_41145 7eb50302733913b7f140a273dfafd024 170 Pfam PF02834 LigT like Phosphoesterase 88 148 7.6E-8 T 14-10-2018 IPR014051 Phosphoesterase, HXTX A4R43_41145 7eb50302733913b7f140a273dfafd024 170 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 159 18.34 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 Gene3D G3DSA:2.30.30.790 3 114 3.4E-15 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.1E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.1E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.1E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 30.674 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 Pfam PF01245 Ribosomal protein L19 4 112 1.9E-51 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 8.0E-51 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 PIRSF PIRSF002191 1 117 4.5E-52 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18445 d75a5eed06df10a94064e8b812197526 117 SUPERFAMILY SSF50104 1 114 2.51E-48 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4R43_05580 82f1dd3fe55e7256d08f635ac60c08cb 188 SUPERFAMILY SSF52833 4 181 1.05E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_05580 82f1dd3fe55e7256d08f635ac60c08cb 188 Pfam PF00578 AhpC/TSA family 29 159 4.5E-8 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_23460 2c425e8b1c5c55fb845236b5dcf751b3 982 Gene3D G3DSA:3.40.50.300 741 979 3.1E-25 T 14-10-2018 A4R43_23460 2c425e8b1c5c55fb845236b5dcf751b3 982 Gene3D G3DSA:3.40.50.300 1 276 6.8E-37 T 14-10-2018 A4R43_23460 2c425e8b1c5c55fb845236b5dcf751b3 982 Pfam PF13476 AAA domain 5 194 1.2E-23 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain A4R43_23460 2c425e8b1c5c55fb845236b5dcf751b3 982 SUPERFAMILY SSF52540 1 970 9.0E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23460 2c425e8b1c5c55fb845236b5dcf751b3 982 Pfam PF13558 Putative exonuclease SbcCD, C subunit 879 940 3.0E-12 T 14-10-2018 A4R43_09010 ae5136e5e833c06be6cd50c80d0e3ddc 1082 Pfam PF07971 Glycosyl hydrolase family 92 396 925 9.0E-146 T 14-10-2018 IPR012939 Glycosyl hydrolase family 92 A4R43_09010 ae5136e5e833c06be6cd50c80d0e3ddc 1082 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 187 929 1.1E-138 T 14-10-2018 IPR005887 Alpha-1,2-mannosidase, putative A4R43_09010 ae5136e5e833c06be6cd50c80d0e3ddc 1082 Gene3D G3DSA:3.30.2080.10 455 928 1.1E-241 T 14-10-2018 A4R43_09010 ae5136e5e833c06be6cd50c80d0e3ddc 1082 Gene3D G3DSA:2.60.120.260 957 1079 2.5E-6 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_09010 ae5136e5e833c06be6cd50c80d0e3ddc 1082 Gene3D G3DSA:2.70.98.10 190 524 1.1E-241 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_09010 ae5136e5e833c06be6cd50c80d0e3ddc 1082 Gene3D G3DSA:1.20.1050.60 525 618 1.1E-241 T 14-10-2018 A4R43_09010 ae5136e5e833c06be6cd50c80d0e3ddc 1082 Gene3D G3DSA:1.20.1610.10 619 799 1.1E-241 T 14-10-2018 A4R43_09010 ae5136e5e833c06be6cd50c80d0e3ddc 1082 SUPERFAMILY SSF48208 425 911 2.38E-11 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_07785 83686dca7b25cc746af74b8f80f0b5e6 598 SMART SM00382 386 574 1.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_07785 83686dca7b25cc746af74b8f80f0b5e6 598 SUPERFAMILY SSF90123 32 348 5.89E-48 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_07785 83686dca7b25cc746af74b8f80f0b5e6 598 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_07785 83686dca7b25cc746af74b8f80f0b5e6 598 Pfam PF00005 ABC transporter 377 522 1.3E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_07785 83686dca7b25cc746af74b8f80f0b5e6 598 Gene3D G3DSA:1.20.1560.10 8 347 7.7E-44 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_07785 83686dca7b25cc746af74b8f80f0b5e6 598 SUPERFAMILY SSF52540 355 592 6.25E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_07785 83686dca7b25cc746af74b8f80f0b5e6 598 Gene3D G3DSA:3.40.50.300 353 598 8.1E-79 T 14-10-2018 A4R43_07785 83686dca7b25cc746af74b8f80f0b5e6 598 Pfam PF00664 ABC transporter transmembrane region 77 258 8.9E-20 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_40845 072cf412e94d0a36954ec388c354862c 427 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 398 1.9E-72 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4R43_40845 072cf412e94d0a36954ec388c354862c 427 Gene3D G3DSA:1.20.1720.10 10 239 5.3E-43 T 14-10-2018 A4R43_40845 072cf412e94d0a36954ec388c354862c 427 Gene3D G3DSA:1.20.1250.20 241 426 7.6E-19 T 14-10-2018 A4R43_40845 072cf412e94d0a36954ec388c354862c 427 SUPERFAMILY SSF103473 4 422 2.75E-62 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_40845 072cf412e94d0a36954ec388c354862c 427 Pfam PF07690 Major Facilitator Superfamily 15 389 4.1E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_40845 072cf412e94d0a36954ec388c354862c 427 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 5.4E-7 T 14-10-2018 A4R43_40845 072cf412e94d0a36954ec388c354862c 427 PRINTS PR01036 Tetracycline resistance protein TetB signature 198 216 5.4E-7 T 14-10-2018 A4R43_40845 072cf412e94d0a36954ec388c354862c 427 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 5.4E-7 T 14-10-2018 A4R43_13640 25f8f4d6527d23e0f1a878e93aae9671 273 PIRSF PIRSF028756 16 270 2.1E-74 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 A4R43_13640 25f8f4d6527d23e0f1a878e93aae9671 273 Gene3D G3DSA:3.40.50.300 6 269 9.4E-104 T 14-10-2018 A4R43_13640 25f8f4d6527d23e0f1a878e93aae9671 273 SUPERFAMILY SSF52540 57 233 1.54E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13640 25f8f4d6527d23e0f1a878e93aae9671 273 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 26 262 4.6E-99 T 14-10-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 KEGG: 00190+2.7.4.1 A4R43_13640 25f8f4d6527d23e0f1a878e93aae9671 273 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 32 246 6.5E-70 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related A4R43_00640 19c2b8db7f10decd2fe52ca4fa45f97f 198 SUPERFAMILY SSF46689 9 76 1.12E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00640 19c2b8db7f10decd2fe52ca4fa45f97f 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 66 6.6E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00640 19c2b8db7f10decd2fe52ca4fa45f97f 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.1E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00640 19c2b8db7f10decd2fe52ca4fa45f97f 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.1E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00640 19c2b8db7f10decd2fe52ca4fa45f97f 198 Gene3D G3DSA:1.10.357.10 14 191 7.4E-23 T 14-10-2018 A4R43_33095 ffa5f201c4963c66100cd8f505ec0542 461 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 50 461 46.997 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33095 ffa5f201c4963c66100cd8f505ec0542 461 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 95 106 - T 14-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33095 ffa5f201c4963c66100cd8f505ec0542 461 Gene3D G3DSA:1.10.645.20 57 461 2.6E-163 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33095 ffa5f201c4963c66100cd8f505ec0542 461 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 173 461 7.6E-109 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33095 ffa5f201c4963c66100cd8f505ec0542 461 SUPERFAMILY SSF56762 68 461 3.66E-122 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33095 ffa5f201c4963c66100cd8f505ec0542 461 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 58 461 1.4E-165 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_08505 884902c28f05c9ab381f5d801ab7a71e 401 Gene3D G3DSA:3.50.50.60 7 335 6.0E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_08505 884902c28f05c9ab381f5d801ab7a71e 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 4.0E-8 T 14-10-2018 A4R43_08505 884902c28f05c9ab381f5d801ab7a71e 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 4.0E-8 T 14-10-2018 A4R43_08505 884902c28f05c9ab381f5d801ab7a71e 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 4.0E-8 T 14-10-2018 A4R43_08505 884902c28f05c9ab381f5d801ab7a71e 401 Gene3D G3DSA:3.30.9.50 40 265 6.0E-58 T 14-10-2018 A4R43_08505 884902c28f05c9ab381f5d801ab7a71e 401 SUPERFAMILY SSF51905 4 366 1.47E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_08505 884902c28f05c9ab381f5d801ab7a71e 401 Pfam PF01494 FAD binding domain 5 312 1.6E-10 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_35880 4f3ce235fb2aeee4d58ac92d12833b85 392 Gene3D G3DSA:3.40.50.720 15 265 8.7E-85 T 14-10-2018 A4R43_35880 4f3ce235fb2aeee4d58ac92d12833b85 392 Pfam PF00581 Rhodanese-like domain 291 383 4.4E-13 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_35880 4f3ce235fb2aeee4d58ac92d12833b85 392 SUPERFAMILY SSF69572 9 359 1.44E-97 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A4R43_35880 4f3ce235fb2aeee4d58ac92d12833b85 392 Gene3D G3DSA:3.40.250.10 274 389 8.8E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_35880 4f3ce235fb2aeee4d58ac92d12833b85 392 SMART SM00450 290 387 1.1E-26 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_35880 4f3ce235fb2aeee4d58ac92d12833b85 392 Pfam PF00899 ThiF family 23 259 5.2E-61 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4R43_38055 98fe4f9180816eb45cf82631a224c57c 161 SUPERFAMILY SSF54427 33 158 6.31E-30 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_38055 98fe4f9180816eb45cf82631a224c57c 161 Pfam PF14534 Domain of unknown function (DUF4440) 39 148 1.8E-7 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 A4R43_38055 98fe4f9180816eb45cf82631a224c57c 161 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 33 155 2.2E-22 T 14-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 A4R43_38055 98fe4f9180816eb45cf82631a224c57c 161 Gene3D G3DSA:3.10.450.50 24 159 8.5E-32 T 14-10-2018 A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 Gene3D G3DSA:1.10.10.10 4 72 5.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 Gene3D G3DSA:1.20.120.530 91 230 4.5E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 SUPERFAMILY SSF46785 7 80 4.25E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.0E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.0E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 Pfam PF07729 FCD domain 96 218 6.1E-21 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 SMART SM00895 96 219 5.6E-17 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 SMART SM00345 8 67 1.0E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 SUPERFAMILY SSF48008 92 224 5.49E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_39215 e1c206a383da0a0ab1d25f2f8787d8fb 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 8.1E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23495 9752d7af3f252ac121367885a2257be5 419 Pfam PF02601 Exonuclease VII, large subunit 335 407 1.1E-7 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A4R43_23495 9752d7af3f252ac121367885a2257be5 419 Pfam PF02601 Exonuclease VII, large subunit 134 353 2.5E-56 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A4R43_23495 9752d7af3f252ac121367885a2257be5 419 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 409 7.6E-109 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A4R43_23495 9752d7af3f252ac121367885a2257be5 419 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 10 410 23.081 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A4R43_23495 9752d7af3f252ac121367885a2257be5 419 Pfam PF13742 OB-fold nucleic acid binding domain 17 110 8.9E-14 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 Pfam PF01019 Gamma-glutamyltranspeptidase 28 582 1.4E-107 T 14-10-2018 A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 SUPERFAMILY SSF56235 2 589 9.26E-122 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 Gene3D G3DSA:3.60.20.40 401 589 2.8E-44 T 14-10-2018 A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 Gene3D G3DSA:1.10.246.130 260 374 1.5E-15 T 14-10-2018 A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 1.3E-20 T 14-10-2018 A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 106 124 1.3E-20 T 14-10-2018 A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 243 259 1.3E-20 T 14-10-2018 A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 401 419 1.3E-20 T 14-10-2018 A4R43_28820 4f9e81b7c0c1e53a7bcc118129dc448c 590 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 455 470 1.3E-20 T 14-10-2018 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 SUPERFAMILY SSF52540 10 580 8.77E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14485 292f3d54861e48f699f255348aa8130c 953 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 Gene3D G3DSA:1.10.8.280 292 409 3.4E-264 T 14-10-2018 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 Gene3D G3DSA:1.20.1580.10 91 503 3.4E-264 T 14-10-2018 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 Gene3D G3DSA:3.40.50.300 627 946 2.2E-144 T 14-10-2018 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 Gene3D G3DSA:1.20.1580.10 702 840 2.2E-144 T 14-10-2018 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 ProSitePatterns PS00211 ABC transporters family signature. 840 854 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 Gene3D G3DSA:3.40.50.300 6 605 3.4E-264 T 14-10-2018 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 935 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 Gene3D G3DSA:3.30.190.20 131 242 3.4E-264 T 14-10-2018 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 Pfam PF00005 ABC transporter 635 870 1.0E-8 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14485 292f3d54861e48f699f255348aa8130c 953 SUPERFAMILY SSF52540 625 924 1.5E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14485 292f3d54861e48f699f255348aa8130c 953 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 950 22.802 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 A4R43_22975 5d74dc7b53acb90c65c7b8a49889798e 289 Gene3D G3DSA:3.20.20.30 5 285 1.9E-55 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_22975 5d74dc7b53acb90c65c7b8a49889798e 289 SUPERFAMILY SSF51679 12 283 8.98E-49 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_22975 5d74dc7b53acb90c65c7b8a49889798e 289 Pfam PF00296 Luciferase-like monooxygenase 10 262 7.7E-40 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_03715 ab8d80ff655c48687b84dfb9fb98048a 242 Gene3D G3DSA:3.30.450.20 4 180 2.8E-17 T 14-10-2018 A4R43_20600 525083104bcb0203ce8a60dfce5248a8 209 SUPERFAMILY SSF51182 75 193 2.89E-7 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_31890 325ca8422db6999fc01b77cd3ffa72ec 303 Gene3D G3DSA:3.20.20.80 98 303 6.6E-83 T 14-10-2018 A4R43_31890 325ca8422db6999fc01b77cd3ffa72ec 303 SUPERFAMILY SSF51445 100 302 4.0E-65 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_31890 325ca8422db6999fc01b77cd3ffa72ec 303 SMART SM00641 101 210 2.2E-46 T 14-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup A4R43_31890 325ca8422db6999fc01b77cd3ffa72ec 303 Pfam PF01183 Glycosyl hydrolases family 25 104 284 9.3E-51 T 14-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 A4R43_31890 325ca8422db6999fc01b77cd3ffa72ec 303 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 105 138 - T 14-10-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 A4R43_09645 e2945bda348b8916d6f70b2d079c403b 412 Pfam PF01266 FAD dependent oxidoreductase 30 376 2.0E-56 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_09645 e2945bda348b8916d6f70b2d079c403b 412 Gene3D G3DSA:3.50.50.60 30 386 3.4E-124 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09645 e2945bda348b8916d6f70b2d079c403b 412 SUPERFAMILY SSF54373 258 337 1.28E-6 T 14-10-2018 A4R43_09645 e2945bda348b8916d6f70b2d079c403b 412 SUPERFAMILY SSF51905 28 400 7.13E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09645 e2945bda348b8916d6f70b2d079c403b 412 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 19 404 9.1E-186 T 14-10-2018 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 A4R43_09645 e2945bda348b8916d6f70b2d079c403b 412 Gene3D G3DSA:3.30.9.10 111 342 3.4E-124 T 14-10-2018 A4R43_41340 51b7179bfd2b7fd002693f270df70c92 356 Pfam PF00962 Adenosine/AMP deaminase 17 334 1.3E-71 T 14-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4R43_41340 51b7179bfd2b7fd002693f270df70c92 356 SUPERFAMILY SSF51556 12 340 5.65E-77 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_41340 51b7179bfd2b7fd002693f270df70c92 356 Gene3D G3DSA:3.20.20.140 2 342 6.0E-98 T 14-10-2018 A4R43_41340 51b7179bfd2b7fd002693f270df70c92 356 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 17 337 2.0E-79 T 14-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A4R43_34180 13c0fcccab8263e22fd44c927851fe52 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 70 84 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_34180 13c0fcccab8263e22fd44c927851fe52 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 143 3.6E-32 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_34180 13c0fcccab8263e22fd44c927851fe52 349 SUPERFAMILY SSF50129 9 182 7.0E-57 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_34180 13c0fcccab8263e22fd44c927851fe52 349 Pfam PF00107 Zinc-binding dehydrogenase 184 305 2.1E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_34180 13c0fcccab8263e22fd44c927851fe52 349 Gene3D G3DSA:3.90.180.10 18 329 2.0E-116 T 14-10-2018 A4R43_34180 13c0fcccab8263e22fd44c927851fe52 349 Gene3D G3DSA:3.40.50.720 161 291 2.0E-116 T 14-10-2018 A4R43_34180 13c0fcccab8263e22fd44c927851fe52 349 SUPERFAMILY SSF51735 150 304 4.85E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_32690 a5ec0483685c7808fa28ff2326c9da76 98 Pfam PF10724 Protein of unknown function (DUF2516) 4 95 4.8E-30 T 14-10-2018 IPR019662 Protein of unknown function DUF2516 A4R43_19005 4fbb3e3a4c19ababf4f1217d9f814672 385 Pfam PF06187 Protein of unknown function (DUF993) 5 384 1.1E-170 T 14-10-2018 IPR009334 Protein of unknown function DUF993 A4R43_19005 4fbb3e3a4c19ababf4f1217d9f814672 385 SUPERFAMILY SSF51569 57 321 1.06E-6 T 14-10-2018 A4R43_19005 4fbb3e3a4c19ababf4f1217d9f814672 385 Gene3D G3DSA:3.20.20.500 2 380 2.1E-161 T 14-10-2018 A4R43_33645 f43c341f3bf2c9cfaef711706a345f8e 319 SUPERFAMILY SSF54427 229 297 4.09E-5 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_40505 e14fd1468d55d2e98a82e5e593995911 377 SUPERFAMILY SSF140453 12 98 8.11E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_40505 e14fd1468d55d2e98a82e5e593995911 377 Gene3D G3DSA:1.10.530.10 211 371 5.4E-11 T 14-10-2018 A4R43_40505 e14fd1468d55d2e98a82e5e593995911 377 Pfam PF01464 Transglycosylase SLT domain 221 347 2.1E-6 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 A4R43_40505 e14fd1468d55d2e98a82e5e593995911 377 SUPERFAMILY SSF53955 211 335 2.06E-7 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_25575 f82bfefe766e3822a3150831a6bb67b7 462 Pfam PF13520 Amino acid permease 29 413 1.8E-40 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_25575 f82bfefe766e3822a3150831a6bb67b7 462 Gene3D G3DSA:1.20.1740.10 19 454 1.6E-79 T 14-10-2018 A4R43_25575 f82bfefe766e3822a3150831a6bb67b7 462 PIRSF PIRSF006060 2 459 3.9E-74 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_35345 8efc5d4de34e811cffda5efe3441f45f 578 Gene3D G3DSA:3.30.300.30 460 577 1.3E-37 T 14-10-2018 A4R43_35345 8efc5d4de34e811cffda5efe3441f45f 578 SUPERFAMILY SSF56801 14 570 3.01E-104 T 14-10-2018 A4R43_35345 8efc5d4de34e811cffda5efe3441f45f 578 Gene3D G3DSA:3.40.50.12780 7 458 2.7E-145 T 14-10-2018 A4R43_35345 8efc5d4de34e811cffda5efe3441f45f 578 Pfam PF00501 AMP-binding enzyme 27 465 8.7E-77 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_40575 cb81ef81f09ad9c50cd2a96f9ff6701c 411 Gene3D G3DSA:1.10.10.2840 283 408 1.8E-14 T 14-10-2018 A4R43_40575 cb81ef81f09ad9c50cd2a96f9ff6701c 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 348 401 4.7E-12 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_27075 a7e6817e83825d7e8dcbfc8ed5ff5e8a 164 SUPERFAMILY SSF53271 7 149 1.09E-24 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_27075 a7e6817e83825d7e8dcbfc8ed5ff5e8a 164 Pfam PF00156 Phosphoribosyl transferase domain 14 149 4.5E-19 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4R43_27075 a7e6817e83825d7e8dcbfc8ed5ff5e8a 164 Gene3D G3DSA:3.40.50.2020 2 160 2.9E-36 T 14-10-2018 A4R43_14410 6e2b7fda16208a98bd7def97a7d6b761 532 Pfam PF07969 Amidohydrolase family 44 507 1.4E-47 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_14410 6e2b7fda16208a98bd7def97a7d6b761 532 SUPERFAMILY SSF51556 55 465 5.45E-73 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_14410 6e2b7fda16208a98bd7def97a7d6b761 532 Gene3D G3DSA:3.20.20.140 306 459 2.8E-19 T 14-10-2018 A4R43_14410 6e2b7fda16208a98bd7def97a7d6b761 532 SUPERFAMILY SSF51338 2 516 8.42E-23 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_14410 6e2b7fda16208a98bd7def97a7d6b761 532 Gene3D G3DSA:3.20.20.140 54 301 2.6E-80 T 14-10-2018 A4R43_05140 09a4a0aa3ed4abf674cce98dd590ca5a 245 Pfam PF13580 SIS domain 10 144 3.6E-34 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_05140 09a4a0aa3ed4abf674cce98dd590ca5a 245 SUPERFAMILY SSF53697 14 192 7.28E-16 T 14-10-2018 A4R43_05140 09a4a0aa3ed4abf674cce98dd590ca5a 245 Gene3D G3DSA:3.40.50.10490 3 239 2.8E-60 T 14-10-2018 A4R43_05080 acc609241783851415aafe975d31c7aa 294 Gene3D G3DSA:3.40.190.290 90 282 8.3E-26 T 14-10-2018 A4R43_05080 acc609241783851415aafe975d31c7aa 294 Pfam PF03466 LysR substrate binding domain 87 274 1.4E-18 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_05080 acc609241783851415aafe975d31c7aa 294 SUPERFAMILY SSF53850 90 276 2.02E-20 T 14-10-2018 A4R43_05080 acc609241783851415aafe975d31c7aa 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.0E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_05080 acc609241783851415aafe975d31c7aa 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.0E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_05080 acc609241783851415aafe975d31c7aa 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.0E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_05080 acc609241783851415aafe975d31c7aa 294 Gene3D G3DSA:1.10.10.10 1 81 3.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05080 acc609241783851415aafe975d31c7aa 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 59 4.7E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_05080 acc609241783851415aafe975d31c7aa 294 SUPERFAMILY SSF46785 1 106 2.29E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38340 74aab4f7e848ac13639dc77ec29dca37 118 Pfam PF11774 Lsr2 1 115 2.7E-38 T 14-10-2018 IPR024412 Lsr2 A4R43_38340 74aab4f7e848ac13639dc77ec29dca37 118 Gene3D G3DSA:1.20.890.50 83 118 5.4E-13 T 14-10-2018 A4R43_38340 74aab4f7e848ac13639dc77ec29dca37 118 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 115 2.0E-19 T 14-10-2018 IPR024412 Lsr2 A4R43_38340 74aab4f7e848ac13639dc77ec29dca37 118 Gene3D G3DSA:3.30.60.230 1 60 4.0E-25 T 14-10-2018 A4R43_22790 00dd69310c03decba544736553e8d4c8 222 Gene3D G3DSA:1.20.120.530 80 219 1.3E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_22790 00dd69310c03decba544736553e8d4c8 222 SUPERFAMILY SSF46785 8 94 1.12E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22790 00dd69310c03decba544736553e8d4c8 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 5.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_22790 00dd69310c03decba544736553e8d4c8 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 5.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_22790 00dd69310c03decba544736553e8d4c8 222 SMART SM00895 86 210 1.5E-15 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_22790 00dd69310c03decba544736553e8d4c8 222 Gene3D G3DSA:1.10.10.10 5 76 1.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22790 00dd69310c03decba544736553e8d4c8 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 76 4.0E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_22790 00dd69310c03decba544736553e8d4c8 222 SUPERFAMILY SSF48008 81 216 1.91E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_22790 00dd69310c03decba544736553e8d4c8 222 SMART SM00345 18 76 1.9E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_22790 00dd69310c03decba544736553e8d4c8 222 Pfam PF07729 FCD domain 86 209 1.1E-21 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_22680 ddc7c77a7161238899936b0d9d04d5dc 389 SUPERFAMILY SSF89796 1 387 9.03E-151 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_22680 ddc7c77a7161238899936b0d9d04d5dc 389 Gene3D G3DSA:3.30.1540.10 233 321 3.0E-148 T 14-10-2018 A4R43_22680 ddc7c77a7161238899936b0d9d04d5dc 389 Pfam PF02515 CoA-transferase family III 4 370 1.3E-137 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_22680 ddc7c77a7161238899936b0d9d04d5dc 389 Gene3D G3DSA:3.40.50.10540 3 386 3.0E-148 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_38125 8af2b7858181cc7f71311200cf075ea0 196 SUPERFAMILY SSF48498 85 191 9.34E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_38125 8af2b7858181cc7f71311200cf075ea0 196 Gene3D G3DSA:1.10.357.10 3 191 2.3E-32 T 14-10-2018 A4R43_38125 8af2b7858181cc7f71311200cf075ea0 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 98 190 2.2E-6 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_38125 8af2b7858181cc7f71311200cf075ea0 196 SUPERFAMILY SSF46689 2 83 6.67E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38125 8af2b7858181cc7f71311200cf075ea0 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.7E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38125 8af2b7858181cc7f71311200cf075ea0 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38125 8af2b7858181cc7f71311200cf075ea0 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08900 77de99aedc31f98762bd52da4881a136 460 Pfam PF01145 SPFH domain / Band 7 family 21 191 9.7E-34 T 14-10-2018 IPR001107 Band 7 domain A4R43_08900 77de99aedc31f98762bd52da4881a136 460 PRINTS PR00721 Stomatin signature 24 46 5.1E-34 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_08900 77de99aedc31f98762bd52da4881a136 460 PRINTS PR00721 Stomatin signature 72 93 5.1E-34 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_08900 77de99aedc31f98762bd52da4881a136 460 PRINTS PR00721 Stomatin signature 107 124 5.1E-34 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_08900 77de99aedc31f98762bd52da4881a136 460 PRINTS PR00721 Stomatin signature 127 150 5.1E-34 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_08900 77de99aedc31f98762bd52da4881a136 460 PRINTS PR00721 Stomatin signature 170 191 5.1E-34 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_08900 77de99aedc31f98762bd52da4881a136 460 PRINTS PR00721 Stomatin signature 151 169 5.1E-34 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_08900 77de99aedc31f98762bd52da4881a136 460 ProSitePatterns PS01270 Band 7 protein family signature. 131 159 - T 14-10-2018 IPR018080 Band 7/stomatin-like, conserved site A4R43_08900 77de99aedc31f98762bd52da4881a136 460 SMART SM00244 17 175 4.4E-57 T 14-10-2018 IPR001107 Band 7 domain A4R43_08900 77de99aedc31f98762bd52da4881a136 460 Gene3D G3DSA:3.30.479.30 45 177 1.4E-43 T 14-10-2018 A4R43_08900 77de99aedc31f98762bd52da4881a136 460 SUPERFAMILY SSF117892 48 182 9.55E-40 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily A4R43_40065 8683fcd5ba2d62256f8133d19d83fca5 412 Gene3D G3DSA:3.40.462.20 161 367 1.1E-89 T 14-10-2018 A4R43_40065 8683fcd5ba2d62256f8133d19d83fca5 412 Pfam PF01565 FAD binding domain 3 129 1.7E-18 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_40065 8683fcd5ba2d62256f8133d19d83fca5 412 SUPERFAMILY SSF56176 3 161 4.21E-38 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_40065 8683fcd5ba2d62256f8133d19d83fca5 412 Gene3D G3DSA:3.30.465.10 61 398 1.1E-89 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_40800 244acce54f9a79100d14c4f463f80cd8 280 Gene3D G3DSA:3.20.20.150 3 277 3.0E-43 T 14-10-2018 A4R43_40800 244acce54f9a79100d14c4f463f80cd8 280 Pfam PF01261 Xylose isomerase-like TIM barrel 24 221 6.9E-25 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_40800 244acce54f9a79100d14c4f463f80cd8 280 SUPERFAMILY SSF51658 18 249 2.9E-37 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_17235 02d2401100b2bbd8e9bebe1f8c10bbba 269 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 33 253 29.374 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A4R43_17235 02d2401100b2bbd8e9bebe1f8c10bbba 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 254 1.5E-80 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A4R43_17235 02d2401100b2bbd8e9bebe1f8c10bbba 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 33.403 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A4R43_17235 02d2401100b2bbd8e9bebe1f8c10bbba 269 Gene3D G3DSA:3.20.20.70 1 269 9.5E-110 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17235 02d2401100b2bbd8e9bebe1f8c10bbba 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A4R43_17235 02d2401100b2bbd8e9bebe1f8c10bbba 269 SUPERFAMILY SSF51366 12 257 5.93E-78 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4R43_07130 8dc4fa970fee0b31e69bc12e5c0dfa80 530 Gene3D G3DSA:3.40.462.20 250 502 7.1E-197 T 14-10-2018 A4R43_07130 8dc4fa970fee0b31e69bc12e5c0dfa80 530 Pfam PF08031 Berberine and berberine like 474 526 2.4E-13 T 14-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 A4R43_07130 8dc4fa970fee0b31e69bc12e5c0dfa80 530 SUPERFAMILY SSF56176 42 235 1.54E-35 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_07130 8dc4fa970fee0b31e69bc12e5c0dfa80 530 Gene3D G3DSA:3.30.465.40 42 516 7.1E-197 T 14-10-2018 A4R43_07130 8dc4fa970fee0b31e69bc12e5c0dfa80 530 Pfam PF01565 FAD binding domain 68 194 8.6E-20 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_21955 b763d9fb4715914a43247bffff2010df 124 Pfam PF07883 Cupin domain 38 102 6.7E-14 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_21955 b763d9fb4715914a43247bffff2010df 124 Gene3D G3DSA:2.60.120.10 2 123 1.5E-17 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_21955 b763d9fb4715914a43247bffff2010df 124 SUPERFAMILY SSF51182 10 110 2.48E-21 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_33660 bb148890c2a8674428c65cb1d147d470 224 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 221 21.368 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 A4R43_33660 bb148890c2a8674428c65cb1d147d470 224 Gene3D G3DSA:3.40.50.360 4 220 4.9E-40 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_33660 bb148890c2a8674428c65cb1d147d470 224 SUPERFAMILY SSF52218 5 218 5.54E-34 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_33660 bb148890c2a8674428c65cb1d147d470 224 Pfam PF02525 Flavodoxin-like fold 5 187 8.2E-26 T 14-10-2018 IPR003680 Flavodoxin-like fold A4R43_25335 6c36cf208c99759d0b4319e01430358e 244 Pfam PF10979 Protein of unknown function (DUF2786) 6 44 2.0E-15 T 14-10-2018 IPR024498 Domain of unknown function DUF2786 A4R43_25335 6c36cf208c99759d0b4319e01430358e 244 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 7 231 4.0E-31 T 14-10-2018 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 58 285 7.6E-52 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 SMART SM01217 737 804 6.9E-22 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 Gene3D G3DSA:3.20.20.300 15 685 8.6E-210 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 SUPERFAMILY SSF56988 441 594 4.84E-6 T 14-10-2018 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 321 701 1.1E-59 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 70 89 4.3E-32 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 147 163 4.3E-32 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 116 132 4.3E-32 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 41 57 4.3E-32 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 217 235 4.3E-32 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 Gene3D G3DSA:3.40.50.1700 297 640 8.6E-210 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 SUPERFAMILY SSF51445 6 301 6.63E-89 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 Gene3D G3DSA:2.60.40.10 703 816 2.4E-29 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 Pfam PF07691 PA14 domain 442 518 1.6E-6 T 14-10-2018 IPR011658 PA14 domain A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 Gene3D G3DSA:2.60.120.260 386 540 8.6E-210 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 SUPERFAMILY SSF52279 320 704 2.48E-52 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_09430 902a7e4b479cdb547621de445ca68ce9 817 Pfam PF14310 Fibronectin type III-like domain 737 803 1.3E-18 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_27795 8489d7b7e5b880d2c9b9a055b66b218d 274 SUPERFAMILY SSF56601 27 270 7.37E-15 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_13015 38a6909f303211b323de070483f111a3 397 Pfam PF13576 Pentapeptide repeats (9 copies) 258 305 4.8E-7 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_31530 611de8c118530ffaf51630fa9df7e2ad 136 SUPERFAMILY SSF54593 1 133 3.54E-29 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_31530 611de8c118530ffaf51630fa9df7e2ad 136 Gene3D G3DSA:3.10.180.10 9 132 6.0E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_31530 611de8c118530ffaf51630fa9df7e2ad 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 131 1.5E-18 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_38950 528e11c5368e92b083b55eb314e8d02a 294 SUPERFAMILY SSF51679 11 289 1.18E-58 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_38950 528e11c5368e92b083b55eb314e8d02a 294 Pfam PF00296 Luciferase-like monooxygenase 9 230 2.2E-51 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_38950 528e11c5368e92b083b55eb314e8d02a 294 Gene3D G3DSA:3.20.20.30 2 287 1.7E-66 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_38950 528e11c5368e92b083b55eb314e8d02a 294 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 17 256 4.6E-62 T 14-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 SUPERFAMILY SSF52172 2 124 1.57E-29 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 Gene3D G3DSA:3.40.50.12740 3 214 1.6E-65 T 14-10-2018 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 4.1E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 Pfam PF00072 Response regulator receiver domain 5 117 4.8E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 SMART SM00448 3 117 8.5E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 SMART SM00421 151 208 1.4E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05095 472c46f0e10c560888c428e9509dbeec 218 SUPERFAMILY SSF46894 149 214 1.33E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_01385 2d990c8562e3d3b4ada155d95c8eef15 168 Gene3D G3DSA:3.10.690.10 1 139 1.7E-34 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 A4R43_01385 2d990c8562e3d3b4ada155d95c8eef15 168 Pfam PF02577 Bifunctional nuclease 5 129 1.2E-32 T 14-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 A4R43_01385 2d990c8562e3d3b4ada155d95c8eef15 168 SUPERFAMILY SSF103256 2 137 9.02E-32 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 A4R43_39370 aa024e60dedabf77bfac8bc725055409 219 Pfam PF10531 SLBB domain 82 132 2.9E-11 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_39370 aa024e60dedabf77bfac8bc725055409 219 Pfam PF12836 Helix-hairpin-helix motif 155 217 8.5E-23 T 14-10-2018 A4R43_39370 aa024e60dedabf77bfac8bc725055409 219 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 156 218 1.9E-16 T 14-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain A4R43_39370 aa024e60dedabf77bfac8bc725055409 219 SUPERFAMILY SSF47781 135 218 8.56E-28 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_39370 aa024e60dedabf77bfac8bc725055409 219 SMART SM00278 166 185 0.0045 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_39370 aa024e60dedabf77bfac8bc725055409 219 SMART SM00278 196 215 67.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4R43_39370 aa024e60dedabf77bfac8bc725055409 219 Gene3D G3DSA:1.10.150.310 166 219 1.6E-13 T 14-10-2018 A4R43_39370 aa024e60dedabf77bfac8bc725055409 219 Gene3D G3DSA:3.10.560.10 71 165 2.3E-7 T 14-10-2018 A4R43_06335 a7bf3c2e70c1b76ab6defa4f17004ca9 360 Pfam PF01212 Beta-eliminating lyase 42 292 4.6E-31 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A4R43_06335 a7bf3c2e70c1b76ab6defa4f17004ca9 360 Gene3D G3DSA:3.40.640.10 9 253 8.5E-64 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_06335 a7bf3c2e70c1b76ab6defa4f17004ca9 360 SUPERFAMILY SSF53383 41 317 3.2E-62 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_06335 a7bf3c2e70c1b76ab6defa4f17004ca9 360 Gene3D G3DSA:3.90.1150.10 254 359 4.0E-12 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 ProSitePatterns PS00436 Peroxidases active site signature. 100 111 - T 14-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 Gene3D G3DSA:1.10.420.20 201 405 8.4E-215 T 14-10-2018 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 SUPERFAMILY SSF48113 438 744 8.99E-114 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 Pfam PF00141 Peroxidase 94 403 3.5E-48 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 Pfam PF00141 Peroxidase 410 719 5.1E-38 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 SUPERFAMILY SSF48113 28 437 6.04E-152 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 Gene3D G3DSA:1.10.420.10 596 720 3.7E-150 T 14-10-2018 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 Gene3D G3DSA:1.10.520.10 441 744 3.7E-150 T 14-10-2018 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 Hamap MF_01961 Catalase-peroxidase [katG]. 15 745 42.369 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 75 7.9E-45 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 488 514 7.9E-45 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 36 58 7.9E-45 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 272 295 7.9E-45 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 77 102 7.9E-45 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 264 274 - T 14-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 31 745 0.0 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00458 Haem peroxidase superfamily signature 178 190 1.1E-17 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00458 Haem peroxidase superfamily signature 100 114 1.1E-17 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00458 Haem peroxidase superfamily signature 160 177 1.1E-17 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00458 Haem peroxidase superfamily signature 264 279 1.1E-17 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 PRINTS PR00458 Haem peroxidase superfamily signature 324 339 1.1E-17 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_19715 1f14231c1e26e4f7e1b671b86b86e2ac 745 Gene3D G3DSA:1.10.520.10 32 438 8.4E-215 T 14-10-2018 A4R43_03830 f8c87d26d06e3f6864febd4209474a26 912 Gene3D G3DSA:1.50.10.10 100 834 3.2E-279 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_03830 f8c87d26d06e3f6864febd4209474a26 912 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 305 400 3.0E-23 T 14-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain A4R43_03830 f8c87d26d06e3f6864febd4209474a26 912 PIRSF PIRSF010631 2 835 3.0E-231 T 14-10-2018 IPR016007 Alpha-L-rhamnosidase A4R43_03830 f8c87d26d06e3f6864febd4209474a26 912 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 405 749 1.2E-123 T 14-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain A4R43_03830 f8c87d26d06e3f6864febd4209474a26 912 Gene3D G3DSA:2.60.40.10 3 99 3.2E-16 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_03830 f8c87d26d06e3f6864febd4209474a26 912 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 136 293 1.3E-48 T 14-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal A4R43_03830 f8c87d26d06e3f6864febd4209474a26 912 SUPERFAMILY SSF48208 402 814 3.33E-49 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_03830 f8c87d26d06e3f6864febd4209474a26 912 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 751 824 4.9E-20 T 14-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain A4R43_20415 6061db33621edf267e623fa02e8fcca0 325 SUPERFAMILY SSF53335 37 256 2.86E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_20415 6061db33621edf267e623fa02e8fcca0 325 Pfam PF08241 Methyltransferase domain 76 172 5.3E-23 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_23040 ab32f50288adb60a129d3ab24b862281 103 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 6 98 1.8E-12 T 14-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 A4R43_26470 63edf9ad96eb7b732fbd68fb2a7c1bb1 219 Gene3D G3DSA:1.10.10.10 97 217 1.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26470 63edf9ad96eb7b732fbd68fb2a7c1bb1 219 SMART SM00421 144 201 1.7E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_26470 63edf9ad96eb7b732fbd68fb2a7c1bb1 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 2.4E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_26470 63edf9ad96eb7b732fbd68fb2a7c1bb1 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 2.4E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_26470 63edf9ad96eb7b732fbd68fb2a7c1bb1 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 2.4E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_26470 63edf9ad96eb7b732fbd68fb2a7c1bb1 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_26470 63edf9ad96eb7b732fbd68fb2a7c1bb1 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 198 1.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_26470 63edf9ad96eb7b732fbd68fb2a7c1bb1 219 SUPERFAMILY SSF46894 137 208 1.33E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_35585 37f63fe3b05eb07a6cf492203089e79e 317 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 2 303 7.9E-64 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4R43_06865 7db54f836e6bfc723eba96dc8cc8cbb8 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 179 8.6E-30 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_06865 7db54f836e6bfc723eba96dc8cc8cbb8 185 SUPERFAMILY SSF88659 106 183 1.74E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_06865 7db54f836e6bfc723eba96dc8cc8cbb8 185 Gene3D G3DSA:1.10.1740.10 7 116 5.7E-32 T 14-10-2018 A4R43_06865 7db54f836e6bfc723eba96dc8cc8cbb8 185 SUPERFAMILY SSF88946 9 111 1.53E-30 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_06865 7db54f836e6bfc723eba96dc8cc8cbb8 185 Gene3D G3DSA:1.10.10.10 122 183 1.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06865 7db54f836e6bfc723eba96dc8cc8cbb8 185 Pfam PF04542 Sigma-70 region 2 31 97 2.7E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_06865 7db54f836e6bfc723eba96dc8cc8cbb8 185 Pfam PF08281 Sigma-70, region 4 126 177 1.6E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_17855 0d5a31a8cd00656122a9cda6d7c453cf 217 Pfam PF01569 PAP2 superfamily 120 199 6.9E-7 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_17855 0d5a31a8cd00656122a9cda6d7c453cf 217 Gene3D G3DSA:1.20.144.10 123 214 1.3E-7 T 14-10-2018 A4R43_17855 0d5a31a8cd00656122a9cda6d7c453cf 217 SUPERFAMILY SSF48317 12 206 2.75E-16 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4R43_17855 0d5a31a8cd00656122a9cda6d7c453cf 217 SMART SM00014 96 201 0.0055 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_40580 3feaebdab41af45ad4ac90758b6d55a9 494 Pfam PF13450 NAD(P)-binding Rossmann-like domain 15 68 4.1E-5 T 14-10-2018 A4R43_40580 3feaebdab41af45ad4ac90758b6d55a9 494 Pfam PF00743 Flavin-binding monooxygenase-like 85 350 6.6E-9 T 14-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_40580 3feaebdab41af45ad4ac90758b6d55a9 494 SUPERFAMILY SSF51905 9 395 1.57E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 Pfam PF13411 MerR HTH family regulatory protein 16 82 1.6E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 Gene3D G3DSA:1.10.490.50 172 263 4.1E-29 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 SMART SM00422 15 84 8.5E-27 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 27 40 3.5E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 27 3.5E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 51 71 3.5E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 ProSitePatterns PS00552 MerR-type HTH domain signature. 18 40 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 Pfam PF07739 TipAS antibiotic-recognition domain 145 257 1.2E-30 T 14-10-2018 IPR012925 TipAS antibiotic-recognition domain A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 SUPERFAMILY SSF89082 172 263 3.4E-20 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 Gene3D G3DSA:1.10.1660.10 14 152 4.1E-38 T 14-10-2018 A4R43_10575 9c81ba1edcce153c9ca695ea2b79a9bb 272 SUPERFAMILY SSF46955 15 122 1.06E-27 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_37000 49629867fdb4e0923cf6c9b367c8b9ec 337 SMART SM00833 224 315 3.7E-10 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4R43_37000 49629867fdb4e0923cf6c9b367c8b9ec 337 SUPERFAMILY SSF90002 225 314 7.19E-15 T 14-10-2018 A4R43_37000 49629867fdb4e0923cf6c9b367c8b9ec 337 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 170 3.1E-41 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4R43_37000 49629867fdb4e0923cf6c9b367c8b9ec 337 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 225 314 5.8E-20 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4R43_37000 49629867fdb4e0923cf6c9b367c8b9ec 337 Gene3D G3DSA:3.30.1220.10 205 316 1.6E-9 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily A4R43_37000 49629867fdb4e0923cf6c9b367c8b9ec 337 Gene3D G3DSA:3.40.50.300 2 191 4.0E-49 T 14-10-2018 A4R43_37000 49629867fdb4e0923cf6c9b367c8b9ec 337 SUPERFAMILY SSF52540 3 193 8.18E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_07505 a2e3a1104207b3ae540facb6afb0b625 540 SUPERFAMILY SSF53067 3 325 5.18E-19 T 14-10-2018 A4R43_07505 a2e3a1104207b3ae540facb6afb0b625 540 Pfam PF02543 Carbamoyltransferase N-terminus 113 320 3.7E-46 T 14-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A4R43_07505 a2e3a1104207b3ae540facb6afb0b625 540 Pfam PF02543 Carbamoyltransferase N-terminus 2 73 6.3E-8 T 14-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A4R43_07505 a2e3a1104207b3ae540facb6afb0b625 540 Gene3D G3DSA:3.30.420.350 122 313 1.2E-86 T 14-10-2018 A4R43_07505 a2e3a1104207b3ae540facb6afb0b625 540 Gene3D G3DSA:3.30.420.40 10 320 1.2E-86 T 14-10-2018 A4R43_07505 a2e3a1104207b3ae540facb6afb0b625 540 SUPERFAMILY SSF55821 364 537 6.71E-6 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A4R43_07505 a2e3a1104207b3ae540facb6afb0b625 540 Pfam PF16861 Carbamoyltransferase C-terminus 369 538 4.6E-64 T 14-10-2018 IPR031730 Carbamoyltransferase, C-terminal A4R43_07505 a2e3a1104207b3ae540facb6afb0b625 540 Gene3D G3DSA:3.90.870.20 335 537 7.6E-74 T 14-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily A4R43_10725 acd0671889317886bc9a6476fbad2383 323 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 15 271 15.295 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4R43_10725 acd0671889317886bc9a6476fbad2383 323 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 27 258 5.9E-61 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4R43_10725 acd0671889317886bc9a6476fbad2383 323 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 118 136 6.3E-36 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4R43_10725 acd0671889317886bc9a6476fbad2383 323 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 26 53 6.3E-36 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4R43_10725 acd0671889317886bc9a6476fbad2383 323 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 186 214 6.3E-36 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4R43_10725 acd0671889317886bc9a6476fbad2383 323 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 136 162 6.3E-36 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4R43_10725 acd0671889317886bc9a6476fbad2383 323 ProSitePatterns PS01218 TatC family signature. 186 205 - T 14-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site A4R43_10725 acd0671889317886bc9a6476fbad2383 323 Pfam PF00902 Sec-independent protein translocase protein (TatC) 29 252 1.2E-58 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 322 8.0E-17 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 171 1.6E-44 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 SUPERFAMILY SSF52467 156 350 7.48E-27 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 Gene3D G3DSA:3.40.50.970 3 176 2.2E-50 T 14-10-2018 A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 384 529 3.7E-41 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 Gene3D G3DSA:3.40.50.1220 184 355 1.6E-27 T 14-10-2018 A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 SUPERFAMILY SSF52518 362 536 3.8E-52 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 420 439 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 SUPERFAMILY SSF52518 6 185 1.03E-44 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_12745 1b6d17b03367944b9b87c00fb67e01f8 541 Gene3D G3DSA:3.40.50.970 356 539 6.5E-54 T 14-10-2018 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 SUPERFAMILY SSF51905 1 290 1.19E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 160 3.3E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 289 3.3E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 3.3E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 121 133 3.3E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 99 107 3.3E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 218 239 3.3E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 Gene3D G3DSA:3.50.50.60 5 283 4.6E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 276 1.1E-28 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 Gene3D G3DSA:3.50.50.60 112 221 4.6E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 265 2.8E-18 T 14-10-2018 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.8E-18 T 14-10-2018 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 2.8E-18 T 14-10-2018 A4R43_23940 e0e39ac5439320e38bb2857ba3843f9b 294 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 2.8E-18 T 14-10-2018 A4R43_31760 b47deda3437a835fd80a01dd94765fde 173 SUPERFAMILY SSF88946 4 92 1.06E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31760 b47deda3437a835fd80a01dd94765fde 173 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 162 7.0E-50 T 14-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4R43_31760 b47deda3437a835fd80a01dd94765fde 173 Gene3D G3DSA:1.10.10.10 81 165 1.6E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31760 b47deda3437a835fd80a01dd94765fde 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 161 4.3E-22 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_31760 b47deda3437a835fd80a01dd94765fde 173 SUPERFAMILY SSF88659 101 163 1.01E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_31760 b47deda3437a835fd80a01dd94765fde 173 Pfam PF04542 Sigma-70 region 2 17 79 4.1E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31760 b47deda3437a835fd80a01dd94765fde 173 Gene3D G3DSA:1.10.1740.10 1 80 6.2E-9 T 14-10-2018 A4R43_31760 b47deda3437a835fd80a01dd94765fde 173 Pfam PF08281 Sigma-70, region 4 106 158 2.6E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_33400 219517522e4ec669208778d8aebd560c 189 SUPERFAMILY SSF46689 1 70 4.16E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_33400 219517522e4ec669208778d8aebd560c 189 SUPERFAMILY SSF48498 112 181 4.56E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_33400 219517522e4ec669208778d8aebd560c 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 47 1.5E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33400 219517522e4ec669208778d8aebd560c 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.7E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33400 219517522e4ec669208778d8aebd560c 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.7E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33400 219517522e4ec669208778d8aebd560c 189 Gene3D G3DSA:1.10.357.10 1 182 1.6E-42 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF08659 KR domain 4373 4544 2.7E-54 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF08659 KR domain 2719 2891 2.1E-54 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF08659 KR domain 1303 1480 6.3E-54 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF55048 3710 3771 5.1E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00698 Acyl transferase domain 505 820 1.7E-90 T 14-10-2018 IPR014043 Acyl transferase A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00698 Acyl transferase domain 3590 3896 1.2E-53 T 14-10-2018 IPR014043 Acyl transferase A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00698 Acyl transferase domain 2176 2487 7.2E-52 T 14-10-2018 IPR014043 Acyl transferase A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:1.10.1200.10 1561 1653 5.8E-35 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF14765 Polyketide synthase dehydratase 868 1129 4.0E-46 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF14765 Polyketide synthase dehydratase 3934 4201 2.2E-53 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 234 5.3E-76 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3064 3314 8.1E-94 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1670 1920 2.1E-92 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF47336 4636 4724 5.76E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.50.720 4205 4612 7.3E-118 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.50.720 1135 1553 4.1E-116 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2719 2892 1.7E-52 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4373 4545 3.1E-54 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1303 1481 3.9E-52 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.47.10 3056 3504 5.7E-194 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.47.10 1 426 3.9E-173 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.47.10 1662 2114 5.8E-191 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF51735 2715 2945 2.64E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3227 3243 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3440 3552 4.1E-16 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 362 477 1.0E-16 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2046 2148 7.0E-14 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF52151 503 791 5.23E-65 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.366.10 505 805 1.1E-156 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.366.10 3589 3880 5.6E-160 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.366.10 2174 2472 2.9E-145 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF53901 2 357 1.79E-92 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00550 Phosphopantetheine attachment site 4646 4711 6.8E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00550 Phosphopantetheine attachment site 2977 3043 1.7E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF00550 Phosphopantetheine attachment site 1584 1649 3.5E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00825 Beta-ketoacyl synthase 2 412 3.1E-204 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00825 Beta-ketoacyl synthase 1672 2096 4.8E-226 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00825 Beta-ketoacyl synthase 3066 3490 2.9E-231 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2176 2469 3.9E-119 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3591 3877 2.7E-114 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 507 802 2.9E-122 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF47336 2971 3079 1.57E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF53901 1667 2033 4.81E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 242 359 1.1E-43 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1928 2043 1.9E-42 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3322 3437 8.6E-44 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF51735 4373 4623 2.96E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.10.129.110 3925 4204 2.0E-104 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.10.129.110 857 1134 5.2E-87 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.30.70.3290 2115 2516 2.9E-145 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF52151 2173 2454 1.1E-71 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF55048 2295 2359 9.94E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF51735 1301 1547 1.17E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.40.50.720 2517 2969 2.6E-145 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF52151 3588 3877 4.71E-74 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:1.10.1200.10 2970 3048 4.0E-30 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.30.70.3290 428 849 1.1E-156 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4671 4686 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF51735 4205 4360 4.33E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1833 1849 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:3.30.70.3290 3505 3923 5.6E-160 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3002 3017 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF47336 1576 1685 2.36E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 Gene3D G3DSA:1.10.1200.10 4627 4719 1.7E-31 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM01294 4645 4712 1.0E-5 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM01294 1582 1649 9.9E-4 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM01294 2976 3043 5.5E-6 T 14-10-2018 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00823 Phosphopantetheine attachment site 2975 3047 2.3E-33 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00823 Phosphopantetheine attachment site 1581 1653 1.3E-30 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00823 Phosphopantetheine attachment site 4644 4716 7.5E-30 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF53901 3060 3434 1.43E-105 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00826 868 1028 6.9E-65 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SMART SM00826 3934 4094 4.3E-75 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF55048 630 695 3.01E-14 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF51735 2524 2709 6.69E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 SUPERFAMILY SSF51735 1137 1291 7.48E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07910 eaf0c10c03edf3a02945dfecd2b6acef 4790 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 147 163 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4R43_07280 153997681bc2f2fe1eaca3f63f1dea85 369 Pfam PF07730 Histidine kinase 187 248 3.0E-11 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_07280 153997681bc2f2fe1eaca3f63f1dea85 369 Gene3D G3DSA:3.30.565.10 251 368 6.2E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27760 ab0cf8bc1a2ee3844dc7334357ab43ad 72 SUPERFAMILY SSF50118 10 70 8.5E-5 T 14-10-2018 A4R43_03930 5ac81c8505d8f839ba86bfc6132aafc0 661 SUPERFAMILY SSF50998 317 647 1.18E-10 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4R43_03930 5ac81c8505d8f839ba86bfc6132aafc0 661 Gene3D G3DSA:1.10.3470.10 35 273 8.7E-6 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_03930 5ac81c8505d8f839ba86bfc6132aafc0 661 Pfam PF00950 ABC 3 transport family 11 264 1.4E-63 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A4R43_03930 5ac81c8505d8f839ba86bfc6132aafc0 661 SUPERFAMILY SSF81345 2 261 1.31E-35 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_03930 5ac81c8505d8f839ba86bfc6132aafc0 661 Gene3D G3DSA:2.130.10.10 298 559 6.8E-6 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_27570 17c1ab706f09637f510f8de9174ed0d4 131 SUPERFAMILY SSF50475 19 123 4.58E-12 T 14-10-2018 A4R43_27570 17c1ab706f09637f510f8de9174ed0d4 131 Gene3D G3DSA:2.30.110.10 18 131 2.7E-20 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_27570 17c1ab706f09637f510f8de9174ed0d4 131 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 23 108 2.4E-13 T 14-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 Gene3D G3DSA:3.40.50.720 8 240 2.1E-70 T 14-10-2018 A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PIRSF PIRSF000126 1 247 6.5E-51 T 14-10-2018 A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 SUPERFAMILY SSF51735 3 236 2.73E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_25325 c5b1a69c8d1f4deba97da9717e2ef43b 253 Pfam PF00106 short chain dehydrogenase 6 191 3.5E-58 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13250 8780abac9bec629801be160cf73b4f9e 572 Pfam PF00920 Dehydratase family 37 554 6.7E-170 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_13250 8780abac9bec629801be160cf73b4f9e 572 SUPERFAMILY SSF143975 6 371 1.96E-113 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_13250 8780abac9bec629801be160cf73b4f9e 572 Gene3D G3DSA:3.50.30.80 372 526 9.1E-50 T 14-10-2018 A4R43_13250 8780abac9bec629801be160cf73b4f9e 572 SUPERFAMILY SSF52016 372 559 4.16E-56 T 14-10-2018 A4R43_06095 b4358e2d12371cafa30c8ee9af29716d 246 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 1.3E-23 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_06095 b4358e2d12371cafa30c8ee9af29716d 246 Gene3D G3DSA:3.10.20.30 1 115 2.7E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_06095 b4358e2d12371cafa30c8ee9af29716d 246 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_06095 b4358e2d12371cafa30c8ee9af29716d 246 SUPERFAMILY SSF46548 118 241 1.92E-24 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_06095 b4358e2d12371cafa30c8ee9af29716d 246 Gene3D G3DSA:1.10.1060.10 134 244 5.3E-12 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_06095 b4358e2d12371cafa30c8ee9af29716d 246 SUPERFAMILY SSF54292 2 115 2.02E-21 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_06095 b4358e2d12371cafa30c8ee9af29716d 246 Pfam PF12838 4Fe-4S dicluster domain 157 227 2.3E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_06095 b4358e2d12371cafa30c8ee9af29716d 246 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_24395 0ff0aa403bcad3f461d6473948e3f2d3 255 SUPERFAMILY SSF51735 1 140 1.33E-12 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_24395 0ff0aa403bcad3f461d6473948e3f2d3 255 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 146 245 6.9E-14 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4R43_24395 0ff0aa403bcad3f461d6473948e3f2d3 255 Gene3D G3DSA:3.40.50.720 1 147 2.2E-17 T 14-10-2018 A4R43_24395 0ff0aa403bcad3f461d6473948e3f2d3 255 SUPERFAMILY SSF48179 146 243 9.35E-11 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_24395 0ff0aa403bcad3f461d6473948e3f2d3 255 Gene3D G3DSA:1.10.3730.10 148 249 4.7E-12 T 14-10-2018 A4R43_24395 0ff0aa403bcad3f461d6473948e3f2d3 255 PIRSF PIRSF000193 1 249 5.5E-36 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4R43_24395 0ff0aa403bcad3f461d6473948e3f2d3 255 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 1 85 1.1E-5 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A4R43_19465 f8491ea4f1248be696eab6323c3280ff 230 SMART SM00345 29 87 3.8E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19465 f8491ea4f1248be696eab6323c3280ff 230 Pfam PF07729 FCD domain 97 215 1.0E-14 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_19465 f8491ea4f1248be696eab6323c3280ff 230 SUPERFAMILY SSF48008 92 226 9.94E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_19465 f8491ea4f1248be696eab6323c3280ff 230 SUPERFAMILY SSF46785 21 91 1.36E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19465 f8491ea4f1248be696eab6323c3280ff 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 87 1.8E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19465 f8491ea4f1248be696eab6323c3280ff 230 Gene3D G3DSA:1.10.10.10 23 89 9.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19465 f8491ea4f1248be696eab6323c3280ff 230 SMART SM00895 97 217 5.1E-13 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_19465 f8491ea4f1248be696eab6323c3280ff 230 Gene3D G3DSA:1.20.120.530 91 228 4.8E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_14560 0696f4384583a3bd24c48ff95626fc7b 316 SUPERFAMILY SSF53850 5 301 2.33E-55 T 14-10-2018 A4R43_14560 0696f4384583a3bd24c48ff95626fc7b 316 SMART SM00062 72 304 2.1E-44 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_14560 0696f4384583a3bd24c48ff95626fc7b 316 Gene3D G3DSA:3.40.190.10 159 262 3.6E-63 T 14-10-2018 A4R43_14560 0696f4384583a3bd24c48ff95626fc7b 316 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 96 109 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site A4R43_14560 0696f4384583a3bd24c48ff95626fc7b 316 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 73 301 4.3E-57 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_14560 0696f4384583a3bd24c48ff95626fc7b 316 Gene3D G3DSA:3.40.190.10 69 293 3.6E-63 T 14-10-2018 A4R43_35945 b69cf211605ba036ad5122e5b6891dd4 276 SUPERFAMILY SSF63380 3 132 9.14E-12 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_35945 b69cf211605ba036ad5122e5b6891dd4 276 Pfam PF04954 Siderophore-interacting protein 134 251 2.3E-36 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain A4R43_35945 b69cf211605ba036ad5122e5b6891dd4 276 Pfam PF08021 Siderophore-interacting FAD-binding domain 8 123 1.2E-30 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting A4R43_35945 b69cf211605ba036ad5122e5b6891dd4 276 Gene3D G3DSA:3.40.50.80 129 269 2.0E-41 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_35945 b69cf211605ba036ad5122e5b6891dd4 276 Gene3D G3DSA:2.40.30.10 1 125 6.1E-34 T 14-10-2018 A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 39 600 6.9E-232 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 SUPERFAMILY SSF52467 221 391 6.7E-63 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 Gene3D G3DSA:3.40.50.1220 223 390 1.7E-64 T 14-10-2018 A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 Gene3D G3DSA:3.40.50.970 398 606 2.5E-70 T 14-10-2018 A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 228 363 4.6E-48 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 SUPERFAMILY SSF52518 401 604 1.3E-67 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 39 204 1.5E-55 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 461 480 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 SUPERFAMILY SSF52518 33 218 2.15E-60 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 424 577 1.5E-48 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_20000 4d56da0cc6a4aa0d1aeca25e64f470ad 615 Gene3D G3DSA:3.40.50.970 34 212 1.6E-68 T 14-10-2018 A4R43_14230 c67305db000627b7edca0cc95822365d 306 Gene3D G3DSA:3.40.50.10330 66 290 3.1E-88 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A4R43_14230 c67305db000627b7edca0cc95822365d 306 Pfam PF01513 ATP-NAD kinase 7 276 1.8E-59 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A4R43_14230 c67305db000627b7edca0cc95822365d 306 Gene3D G3DSA:2.60.200.30 133 269 3.1E-88 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A4R43_14230 c67305db000627b7edca0cc95822365d 306 Hamap MF_00361 NAD kinase [nadK]. 5 292 29.254 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A4R43_14230 c67305db000627b7edca0cc95822365d 306 SUPERFAMILY SSF111331 6 298 1.83E-77 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A4R43_02790 f90f6831102d6021c9d9f515d8e70af4 133 Gene3D G3DSA:3.10.180.10 1 132 3.2E-39 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_02790 f90f6831102d6021c9d9f515d8e70af4 133 SUPERFAMILY SSF54593 1 124 1.93E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 Pfam PF00732 GMC oxidoreductase 1 271 6.0E-58 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 SUPERFAMILY SSF51905 2 480 1.94E-71 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 Gene3D G3DSA:3.50.50.60 2 472 4.0E-150 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 PIRSF PIRSF000137 1 307 1.8E-75 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 PIRSF PIRSF000137 311 481 3.9E-40 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 Gene3D G3DSA:3.30.560.10 38 419 4.0E-150 T 14-10-2018 A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 Pfam PF05199 GMC oxidoreductase 341 474 2.7E-36 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 230 244 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_13520 862c7deb3f82117cbd1fc297724a2cc5 481 SUPERFAMILY SSF54373 266 424 5.0E-29 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 SUPERFAMILY SSF51905 147 311 3.51E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 SUPERFAMILY SSF55424 314 382 1.92E-18 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 Pfam PF14759 Reductase C-terminal 321 382 6.4E-11 T 14-10-2018 IPR028202 Reductase, C-terminal A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 SUPERFAMILY SSF51905 5 187 4.67E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.3E-20 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-20 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.3E-20 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.3E-20 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.3E-20 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.8E-15 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 1.8E-15 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.8E-15 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 1.8E-15 T 14-10-2018 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 Gene3D G3DSA:3.50.50.60 116 240 5.2E-95 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 Gene3D G3DSA:3.50.50.60 7 302 5.2E-95 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 301 1.5E-47 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_40195 3c429d4c9a526294b420dc31f64b2b9c 391 Gene3D G3DSA:3.30.390.30 321 386 3.8E-12 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_05975 fe4bd790e1f72f19b0d8f8e2ddfd462d 152 Pfam PF14539 Domain of unknown function (DUF4442) 15 148 1.0E-8 T 14-10-2018 IPR027961 Protein of unknown function DUF4442 A4R43_05975 fe4bd790e1f72f19b0d8f8e2ddfd462d 152 SUPERFAMILY SSF54637 6 150 5.97E-16 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_05975 fe4bd790e1f72f19b0d8f8e2ddfd462d 152 Gene3D G3DSA:3.10.129.10 4 152 1.3E-21 T 14-10-2018 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00385 P450 superfamily signature 246 263 3.2E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00385 P450 superfamily signature 356 367 3.2E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00385 P450 superfamily signature 281 292 3.2E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00385 P450 superfamily signature 347 356 3.2E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 Pfam PF00067 Cytochrome P450 219 377 1.3E-21 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 Gene3D G3DSA:1.10.630.10 17 407 1.2E-123 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 167 182 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 326 341 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 298 325 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 103 114 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 204 226 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 150 166 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 356 367 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 281 292 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 PRINTS PR00359 B-class P450 signature 347 356 7.9E-58 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_36525 be390cbad542803346b8b03b1aea67ce 407 SUPERFAMILY SSF48264 21 407 2.36E-97 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_36430 e197d9ac088733423efa773f3d559b24 76 Pfam PF04149 Domain of unknown function (DUF397) 16 70 8.3E-18 T 14-10-2018 IPR007278 Domain of unknown function DUF397 A4R43_39850 5ecdf7abc07e905552d594095fb094a0 251 SUPERFAMILY SSF53335 9 243 7.35E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_39850 5ecdf7abc07e905552d594095fb094a0 251 Pfam PF13489 Methyltransferase domain 10 137 1.9E-13 T 14-10-2018 A4R43_39850 5ecdf7abc07e905552d594095fb094a0 251 Gene3D G3DSA:3.40.50.150 7 248 7.2E-77 T 14-10-2018 A4R43_39850 5ecdf7abc07e905552d594095fb094a0 251 Gene3D G3DSA:1.10.150.290 128 231 7.2E-77 T 14-10-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 A4R43_32090 02a9598cf70b466d37d34ee0e959e116 296 PIRSF PIRSF021524 1 296 1.0E-106 T 14-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 A4R43_32090 02a9598cf70b466d37d34ee0e959e116 296 Gene3D G3DSA:3.40.630.30 1 296 1.8E-89 T 14-10-2018 A4R43_32090 02a9598cf70b466d37d34ee0e959e116 296 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 4 296 34.439 T 14-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 A4R43_32090 02a9598cf70b466d37d34ee0e959e116 296 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 6 294 2.2E-94 T 14-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 A4R43_32090 02a9598cf70b466d37d34ee0e959e116 296 Pfam PF00583 Acetyltransferase (GNAT) family 36 102 9.6E-6 T 14-10-2018 IPR000182 GNAT domain A4R43_32090 02a9598cf70b466d37d34ee0e959e116 296 Pfam PF00583 Acetyltransferase (GNAT) family 183 285 4.2E-16 T 14-10-2018 IPR000182 GNAT domain A4R43_32090 02a9598cf70b466d37d34ee0e959e116 296 SUPERFAMILY SSF55729 40 288 2.67E-40 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_01685 e158645cd239ce5528fff2bcb560a356 103 SMART SM00418 7 85 1.2E-26 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01685 e158645cd239ce5528fff2bcb560a356 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 7.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01685 e158645cd239ce5528fff2bcb560a356 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 9 24 7.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01685 e158645cd239ce5528fff2bcb560a356 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 7.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01685 e158645cd239ce5528fff2bcb560a356 103 Pfam PF01022 Bacterial regulatory protein, arsR family 14 58 3.8E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_01685 e158645cd239ce5528fff2bcb560a356 103 SUPERFAMILY SSF46785 6 100 4.32E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01685 e158645cd239ce5528fff2bcb560a356 103 Gene3D G3DSA:1.10.10.10 2 103 8.2E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11000 1f92adb9bcc645f29361e43f5401a57e 465 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 182 235 1.7E-5 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A4R43_11000 1f92adb9bcc645f29361e43f5401a57e 465 Gene3D G3DSA:3.40.50.300 43 252 3.9E-30 T 14-10-2018 A4R43_11000 1f92adb9bcc645f29361e43f5401a57e 465 SUPERFAMILY SSF52540 43 321 1.01E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08420 71391a363c3268a945259d3f68437f22 413 Gene3D G3DSA:3.20.20.60 162 413 1.1E-62 T 14-10-2018 A4R43_08420 71391a363c3268a945259d3f68437f22 413 Pfam PF13714 Phosphoenolpyruvate phosphomutase 165 392 1.3E-61 T 14-10-2018 A4R43_08420 71391a363c3268a945259d3f68437f22 413 SUPERFAMILY SSF51621 164 410 5.23E-50 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_08420 71391a363c3268a945259d3f68437f22 413 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 146 155 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_38955 f70e87f62460dffbf532b989baac19b7 148 Pfam PF12680 SnoaL-like domain 24 129 1.4E-15 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_38955 f70e87f62460dffbf532b989baac19b7 148 SUPERFAMILY SSF54427 21 141 4.19E-23 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_38955 f70e87f62460dffbf532b989baac19b7 148 Gene3D G3DSA:3.10.450.50 12 142 8.6E-40 T 14-10-2018 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 Pfam PF03949 Malic enzyme, NAD binding domain 166 383 1.2E-20 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 SUPERFAMILY SSF53223 14 162 3.88E-48 T 14-10-2018 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 SUPERFAMILY SSF51735 164 389 7.74E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 Pfam PF00390 Malic enzyme, N-terminal domain 26 114 2.8E-18 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 Pfam PF00390 Malic enzyme, N-terminal domain 115 152 2.9E-5 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 SMART SM00919 164 384 2.8E-107 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 SMART SM01274 19 152 6.0E-69 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 Gene3D G3DSA:3.40.50.10380 9 161 4.3E-61 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 PIRSF PIRSF000106 10 390 4.8E-69 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 Gene3D G3DSA:3.40.50.720 162 390 1.2E-72 T 14-10-2018 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 PRINTS PR00072 Malic enzyme signature 160 176 2.0E-6 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 PRINTS PR00072 Malic enzyme signature 191 207 2.0E-6 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4R43_23090 e9a64e2cb99c86ee6eca24d8037b3c97 390 PRINTS PR00072 Malic enzyme signature 81 103 2.0E-6 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4R43_22490 c86b56a8b17d92df00ef9594d109d8fb 414 Gene3D G3DSA:1.10.260.40 10 71 4.3E-12 T 14-10-2018 A4R43_22490 c86b56a8b17d92df00ef9594d109d8fb 414 SMART SM00530 15 70 3.3E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_22490 c86b56a8b17d92df00ef9594d109d8fb 414 SUPERFAMILY SSF47413 11 68 6.48E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_22490 c86b56a8b17d92df00ef9594d109d8fb 414 Pfam PF13560 Helix-turn-helix domain 11 69 1.9E-13 T 14-10-2018 A4R43_36210 a1386593b639c7dd93099d00d1a57518 449 Gene3D G3DSA:3.40.309.10 230 412 6.0E-138 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_36210 a1386593b639c7dd93099d00d1a57518 449 Pfam PF00171 Aldehyde dehydrogenase family 5 440 2.0E-123 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_36210 a1386593b639c7dd93099d00d1a57518 449 Gene3D G3DSA:3.40.605.10 7 430 6.0E-138 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_36210 a1386593b639c7dd93099d00d1a57518 449 SUPERFAMILY SSF53720 3 444 6.02E-124 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_36210 a1386593b639c7dd93099d00d1a57518 449 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 226 233 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_25345 5017a01ed40176a0260c57dd272ecb76 221 SMART SM00448 3 113 4.9E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25345 5017a01ed40176a0260c57dd272ecb76 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 218 4.0E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25345 5017a01ed40176a0260c57dd272ecb76 221 SMART SM00862 149 218 1.4E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25345 5017a01ed40176a0260c57dd272ecb76 221 Pfam PF00072 Response regulator receiver domain 5 113 7.6E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25345 5017a01ed40176a0260c57dd272ecb76 221 SUPERFAMILY SSF52172 2 125 2.28E-41 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_25345 5017a01ed40176a0260c57dd272ecb76 221 Gene3D G3DSA:1.10.10.10 130 221 5.2E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25345 5017a01ed40176a0260c57dd272ecb76 221 SUPERFAMILY SSF46894 123 219 5.67E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_25345 5017a01ed40176a0260c57dd272ecb76 221 Gene3D G3DSA:3.40.50.2300 1 129 2.4E-37 T 14-10-2018 A4R43_12245 eb086d499ded315b1236b7567ca8b6a3 378 Pfam PF01882 Protein of unknown function DUF58 187 263 1.3E-19 T 14-10-2018 IPR002881 Domain of unknown function DUF58 A4R43_25210 ef670054d217406ec572dfd2eb8b3f1a 69 SUPERFAMILY SSF46955 13 62 3.3E-8 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_25210 ef670054d217406ec572dfd2eb8b3f1a 69 Pfam PF12728 Helix-turn-helix domain 14 61 7.1E-8 T 14-10-2018 A4R43_13810 402d783afb30ac479bf1eb00ecfa48d8 444 SUPERFAMILY SSF89796 27 191 6.8E-23 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_13810 402d783afb30ac479bf1eb00ecfa48d8 444 Pfam PF02515 CoA-transferase family III 201 389 1.7E-43 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_13810 402d783afb30ac479bf1eb00ecfa48d8 444 Gene3D G3DSA:3.40.50.10540 195 410 8.9E-56 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_13810 402d783afb30ac479bf1eb00ecfa48d8 444 SUPERFAMILY SSF89796 199 403 1.18E-56 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Gene3D G3DSA:3.30.559.30 871 1144 1.6E-72 T 14-10-2018 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SUPERFAMILY SSF47336 1615 1685 1.96E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SUPERFAMILY SSF47336 627 688 2.62E-12 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1014 1155 4.7E-24 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Pfam PF00975 Thioesterase domain 1710 1826 1.2E-23 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 487 9.6E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 ProSitePatterns PS00455 Putative AMP-binding domain signature. 152 163 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Gene3D G3DSA:3.30.300.30 397 499 3.6E-32 T 14-10-2018 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SUPERFAMILY SSF52777 886 1146 3.45E-28 T 14-10-2018 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Gene3D G3DSA:3.30.559.10 1180 1537 1.6E-105 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SUPERFAMILY SSF52777 1180 1352 1.33E-37 T 14-10-2018 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SMART SM00823 Phosphopantetheine attachment site 627 694 1.0E-7 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SMART SM00823 Phosphopantetheine attachment site 1623 1678 0.0056 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Gene3D G3DSA:3.40.50.1820 1613 1948 2.3E-98 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Gene3D G3DSA:1.10.1200.10 626 692 1.2E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 ProSitePatterns PS00012 Phosphopantetheine attachment site. 650 665 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Gene3D G3DSA:3.40.50.12780 3 396 9.6E-124 T 14-10-2018 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SUPERFAMILY SSF52777 1354 1594 8.56E-40 T 14-10-2018 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Gene3D G3DSA:3.30.559.30 1354 1594 1.6E-105 T 14-10-2018 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Pfam PF00668 Condensation domain 1176 1515 2.6E-55 T 14-10-2018 IPR001242 Condensation domain A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Pfam PF00668 Condensation domain 727 1144 1.6E-36 T 14-10-2018 IPR001242 Condensation domain A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Pfam PF00501 AMP-binding enzyme 14 403 1.0E-84 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1647 1662 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 35 427 4.0E-115 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Gene3D G3DSA:3.30.559.10 695 869 2.9E-41 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SUPERFAMILY SSF53474 1690 1946 1.04E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Pfam PF00550 Phosphopantetheine attachment site 1625 1684 8.9E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 Pfam PF00550 Phosphopantetheine attachment site 629 687 1.6E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SUPERFAMILY SSF56801 9 498 3.14E-132 T 14-10-2018 A4R43_12555 f0d7e6997d7694cc34e62f8135ef422e 1954 SUPERFAMILY SSF52777 705 897 4.89E-28 T 14-10-2018 A4R43_22865 235d4e959f10baa0e5232e65c04cfd15 431 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 301 428 5.1E-26 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_22865 235d4e959f10baa0e5232e65c04cfd15 431 Gene3D G3DSA:2.40.110.10 202 296 2.4E-14 T 14-10-2018 A4R43_22865 235d4e959f10baa0e5232e65c04cfd15 431 SUPERFAMILY SSF56645 69 292 2.23E-41 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_22865 235d4e959f10baa0e5232e65c04cfd15 431 SUPERFAMILY SSF47203 300 428 1.77E-33 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_22865 235d4e959f10baa0e5232e65c04cfd15 431 Gene3D G3DSA:1.20.140.10 297 430 3.5E-33 T 14-10-2018 A4R43_22865 235d4e959f10baa0e5232e65c04cfd15 431 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 74 184 2.1E-23 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_22865 235d4e959f10baa0e5232e65c04cfd15 431 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 399 418 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_22865 235d4e959f10baa0e5232e65c04cfd15 431 Gene3D G3DSA:1.10.540.10 65 187 1.1E-27 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_28095 c878d293301be0a9664124bf51b100ab 488 SUPERFAMILY SSF140459 105 256 8.89E-6 T 14-10-2018 A4R43_28095 c878d293301be0a9664124bf51b100ab 488 Gene3D G3DSA:1.20.1260.20 96 258 5.0E-9 T 14-10-2018 IPR038332 PPE superfamily A4R43_17850 37e96e56f70a413566e365091b41355c 294 Pfam PF08338 Domain of unknown function (DUF1731) 244 290 2.1E-17 T 14-10-2018 IPR013549 Domain of unknown function DUF1731 A4R43_17850 37e96e56f70a413566e365091b41355c 294 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 288 6.4E-92 T 14-10-2018 IPR010099 Epimerase family protein SDR39U1 A4R43_17850 37e96e56f70a413566e365091b41355c 294 SUPERFAMILY SSF51735 1 292 4.84E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_17850 37e96e56f70a413566e365091b41355c 294 Gene3D G3DSA:3.40.50.720 1 282 9.9E-73 T 14-10-2018 A4R43_17850 37e96e56f70a413566e365091b41355c 294 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 124 7.1E-11 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 SUPERFAMILY SSF46894 789 845 3.1E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 Pfam PF00196 Bacterial regulatory proteins, luxR family 796 845 1.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 SUPERFAMILY SSF52540 25 202 9.66E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 Gene3D G3DSA:1.10.10.10 712 849 4.6E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 SMART SM00421 794 848 2.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 827 839 7.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 811 827 7.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 797 811 7.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05680 d9dcb28c92b66bb8bfde59d183fe097c 850 ProSitePatterns PS00622 LuxR-type HTH domain signature. 811 838 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SUPERFAMILY SSF49785 266 402 2.34E-15 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Gene3D G3DSA:2.60.40.10 407 509 4.9E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Gene3D G3DSA:2.160.20.10 816 1193 1.6E-19 T 14-10-2018 IPR012334 Pectin lyase fold A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SUPERFAMILY SSF51126 819 1132 3.77E-24 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SMART SM00231 28 170 8.3E-7 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SUPERFAMILY SSF49785 40 170 6.48E-24 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Gene3D G3DSA:2.60.40.10 510 636 4.3E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Pfam PF07705 CARDB 407 507 9.5E-23 T 14-10-2018 IPR011635 CARDB domain A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Gene3D G3DSA:2.60.120.260 267 404 1.8E-24 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Gene3D G3DSA:2.60.120.260 38 175 1.2E-30 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SMART SM00710 1089 1111 500.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SMART SM00710 940 962 700.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SMART SM00710 1122 1152 2700.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SMART SM00710 1019 1042 4600.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SMART SM00710 964 986 640.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Pfam PF00754 F5/8 type C domain 276 398 1.0E-10 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Pfam PF00754 F5/8 type C domain 44 165 1.1E-19 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4R43_22220 60c794173e992ad260eb19dba544d387 1194 SUPERFAMILY SSF49265 175 260 9.3E-9 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_22220 60c794173e992ad260eb19dba544d387 1194 Gene3D G3DSA:2.60.40.10 176 262 1.1E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 SMART SM00421 146 203 2.4E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 SUPERFAMILY SSF52172 3 132 1.21E-30 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 SMART SM00448 3 116 4.5E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 Gene3D G3DSA:3.40.50.12740 3 207 3.7E-66 T 14-10-2018 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 SUPERFAMILY SSF46894 136 206 1.63E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 Pfam PF00072 Response regulator receiver domain 5 116 1.3E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_28500 9e6a2dd1d7628e7313eb3dfc5ce966e8 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 3.5E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_36110 2501df86825b66b35c092b3f8c8c5047 177 Gene3D G3DSA:1.10.1740.10 9 87 4.0E-15 T 14-10-2018 A4R43_36110 2501df86825b66b35c092b3f8c8c5047 177 SUPERFAMILY SSF88946 14 104 1.14E-16 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_36110 2501df86825b66b35c092b3f8c8c5047 177 Pfam PF04542 Sigma-70 region 2 22 90 2.3E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_36110 2501df86825b66b35c092b3f8c8c5047 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 173 1.2E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_36110 2501df86825b66b35c092b3f8c8c5047 177 Gene3D G3DSA:1.10.10.10 108 177 6.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36110 2501df86825b66b35c092b3f8c8c5047 177 Pfam PF08281 Sigma-70, region 4 119 167 1.8E-11 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_36110 2501df86825b66b35c092b3f8c8c5047 177 SUPERFAMILY SSF88659 111 174 2.43E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_16790 11188c8aea18a76af522be282198c78c 238 Gene3D G3DSA:1.20.1260.10 40 215 1.1E-6 T 14-10-2018 IPR012347 Ferritin-like A4R43_16790 11188c8aea18a76af522be282198c78c 238 SUPERFAMILY SSF47240 16 201 1.62E-18 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_29535 16d10dd568cba47c0903c86ab496999d 300 SUPERFAMILY SSF48452 59 170 6.5E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_29535 16d10dd568cba47c0903c86ab496999d 300 Gene3D G3DSA:1.25.40.10 40 292 3.0E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_17865 a12b3c2ed0bd6f16c1376a1d0df6c963 311 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 231 5.9E-95 T 14-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c A4R43_17865 a12b3c2ed0bd6f16c1376a1d0df6c963 311 SUPERFAMILY SSF51679 9 307 1.96E-72 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_17865 a12b3c2ed0bd6f16c1376a1d0df6c963 311 Gene3D G3DSA:3.20.20.30 4 311 1.4E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_17865 a12b3c2ed0bd6f16c1376a1d0df6c963 311 Pfam PF00296 Luciferase-like monooxygenase 8 251 1.9E-53 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_18790 3dbf69168c28963494e65530dcae4851 181 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 111 117 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4R43_18790 3dbf69168c28963494e65530dcae4851 181 Pfam PF03602 Conserved hypothetical protein 95 1 174 6.4E-47 T 14-10-2018 A4R43_18790 3dbf69168c28963494e65530dcae4851 181 Gene3D G3DSA:3.40.50.150 1 179 8.8E-55 T 14-10-2018 A4R43_18790 3dbf69168c28963494e65530dcae4851 181 SUPERFAMILY SSF53335 2 174 1.46E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_18790 3dbf69168c28963494e65530dcae4851 181 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 176 1.2E-45 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A4R43_18790 3dbf69168c28963494e65530dcae4851 181 PIRSF PIRSF004553 1 180 1.8E-51 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 SMART SM00738 76 184 6.3E-51 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 76 266 23.757 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 Gene3D G3DSA:2.30.30.30 207 266 5.2E-25 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 79 266 1.4E-62 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 ProSitePatterns PS01014 Transcription termination factor nusG signature. 249 258 - T 14-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 Pfam PF02357 Transcription termination factor nusG 78 180 4.0E-25 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 SUPERFAMILY SSF50104 210 266 3.01E-17 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 SUPERFAMILY SSF82679 78 181 7.85E-36 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 SMART SM00739 212 239 0.0084 T 14-10-2018 IPR005824 KOW A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 PRINTS PR00338 Transcription termination factor NUSG signature 224 239 5.7E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 PRINTS PR00338 Transcription termination factor NUSG signature 242 258 5.7E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 PRINTS PR00338 Transcription termination factor NUSG signature 131 143 5.7E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4R43_33555 1f04c2924d5066d3f7c24173851c377a 266 Gene3D G3DSA:3.30.70.940 73 191 9.2E-41 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4R43_28770 22648a14073f2d6e75f3c3b5f3198942 591 Pfam PF13524 Glycosyl transferases group 1 203 286 1.1E-5 T 14-10-2018 A4R43_28770 22648a14073f2d6e75f3c3b5f3198942 591 SUPERFAMILY SSF53448 436 548 1.21E-11 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_33410 53da41670534071f2be7b0381ab49075 163 Pfam PF04461 Protein of unknown function (DUF520) 4 163 7.7E-59 T 14-10-2018 IPR007551 Protein of unknown function DUF520 A4R43_33410 53da41670534071f2be7b0381ab49075 163 SUPERFAMILY SSF89963 92 163 1.8E-23 T 14-10-2018 IPR036183 YajQ-like superfamily A4R43_33410 53da41670534071f2be7b0381ab49075 163 SUPERFAMILY SSF89963 4 88 1.18E-24 T 14-10-2018 IPR036183 YajQ-like superfamily A4R43_33410 53da41670534071f2be7b0381ab49075 163 Gene3D G3DSA:3.30.70.860 5 163 7.6E-58 T 14-10-2018 IPR035571 UPF0234-like, C-terminal A4R43_33410 53da41670534071f2be7b0381ab49075 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 24.591 T 14-10-2018 IPR007551 Protein of unknown function DUF520 A4R43_33410 53da41670534071f2be7b0381ab49075 163 Gene3D G3DSA:3.30.70.990 11 100 7.6E-58 T 14-10-2018 IPR035570 UPF0234, N-terminal A4R43_31170 8f6fc5010618a2c77f2136a05ae9c736 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 257 4.6E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_31170 8f6fc5010618a2c77f2136a05ae9c736 269 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 54 149 1.9E-20 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_31170 8f6fc5010618a2c77f2136a05ae9c736 269 SUPERFAMILY SSF161098 53 244 1.31E-38 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_31170 8f6fc5010618a2c77f2136a05ae9c736 269 Gene3D G3DSA:1.10.3720.10 42 261 1.5E-47 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_10240 f83dd41bedeab99472df142e808f560d 266 SMART SM01134 78 239 7.0E-54 T 14-10-2018 A4R43_10240 f83dd41bedeab99472df142e808f560d 266 Gene3D G3DSA:1.10.10.10 4 63 1.6E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10240 f83dd41bedeab99472df142e808f560d 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 2.1E-5 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_10240 f83dd41bedeab99472df142e808f560d 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 2.1E-5 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_10240 f83dd41bedeab99472df142e808f560d 266 Pfam PF00455 DeoR C terminal sensor domain 81 237 3.0E-42 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_10240 f83dd41bedeab99472df142e808f560d 266 SUPERFAMILY SSF46785 9 63 3.68E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_10240 f83dd41bedeab99472df142e808f560d 266 Pfam PF08220 DeoR-like helix-turn-helix domain 11 65 1.4E-12 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_10240 f83dd41bedeab99472df142e808f560d 266 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_10240 f83dd41bedeab99472df142e808f560d 266 SUPERFAMILY SSF100950 82 240 5.23E-25 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_10240 f83dd41bedeab99472df142e808f560d 266 SMART SM00420 11 63 3.5E-11 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_10230 0d06a49b7c3a861334ad6a3c71746947 408 Gene3D G3DSA:3.40.50.10840 1 229 9.8E-78 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily A4R43_10230 0d06a49b7c3a861334ad6a3c71746947 408 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 245 400 3.3E-34 T 14-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain A4R43_10230 0d06a49b7c3a861334ad6a3c71746947 408 Gene3D G3DSA:3.40.980.20 237 408 4.5E-44 T 14-10-2018 A4R43_10230 0d06a49b7c3a861334ad6a3c71746947 408 Pfam PF07005 Putative sugar-binding N-terminal domain 2 223 2.1E-63 T 14-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain A4R43_10230 0d06a49b7c3a861334ad6a3c71746947 408 SUPERFAMILY SSF142764 2 407 2.35E-102 T 14-10-2018 A4R43_34730 098deadca432397bae1066447a1a8d74 258 Gene3D G3DSA:3.10.20.30 13 128 3.5E-31 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_34730 098deadca432397bae1066447a1a8d74 258 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 27 250 1.4E-75 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34730 098deadca432397bae1066447a1a8d74 258 SUPERFAMILY SSF46548 129 254 4.36E-32 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_34730 098deadca432397bae1066447a1a8d74 258 SUPERFAMILY SSF54292 21 128 7.38E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_34730 098deadca432397bae1066447a1a8d74 258 Gene3D G3DSA:1.10.1060.10 129 257 2.1E-47 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_34730 098deadca432397bae1066447a1a8d74 258 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_34730 098deadca432397bae1066447a1a8d74 258 Pfam PF13183 4Fe-4S dicluster domain 168 240 2.4E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_34730 098deadca432397bae1066447a1a8d74 258 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 24 134 3.7E-33 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_14060 2a1bd11689fb13e134ccb8fd6240baad 164 Pfam PF11292 Protein of unknown function (DUF3093) 15 158 2.0E-49 T 14-10-2018 IPR021443 Protein of unknown function DUF3093 A4R43_20285 4a0acd4050d0971db04297603ce4a81b 94 Gene3D G3DSA:2.40.30.100 7 90 1.6E-20 T 14-10-2018 IPR037079 AF2212/PG0164-like superfamily A4R43_20285 4a0acd4050d0971db04297603ce4a81b 94 SUPERFAMILY SSF141694 8 90 2.62E-23 T 14-10-2018 A4R43_20285 4a0acd4050d0971db04297603ce4a81b 94 Pfam PF08922 Domain of unknown function (DUF1905) 10 88 9.8E-22 T 14-10-2018 IPR015018 Protein of unknown function DUF1905 A4R43_35560 af7281e1e221933bf0282a5851e01405 199 Gene3D G3DSA:3.40.50.450 2 197 1.0E-78 T 14-10-2018 A4R43_35560 af7281e1e221933bf0282a5851e01405 199 SUPERFAMILY SSF102405 7 184 6.87E-62 T 14-10-2018 A4R43_35560 af7281e1e221933bf0282a5851e01405 199 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 8 178 2.2E-61 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG A4R43_35560 af7281e1e221933bf0282a5851e01405 199 Pfam PF03641 Possible lysine decarboxylase 52 180 1.2E-42 T 14-10-2018 IPR031100 LOG family A4R43_23590 b174cbc7384276df357e10dfd10c96b0 319 SMART SM00418 244 319 2.5E-4 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_23590 b174cbc7384276df357e10dfd10c96b0 319 Gene3D G3DSA:1.10.10.10 234 317 1.7E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23590 b174cbc7384276df357e10dfd10c96b0 319 Pfam PF12840 Helix-turn-helix domain 246 301 1.4E-8 T 14-10-2018 A4R43_23590 b174cbc7384276df357e10dfd10c96b0 319 SUPERFAMILY SSF46785 245 317 2.52E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 Pfam PF01037 Lrp/AsnC ligand binding domain 73 140 3.7E-13 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 SUPERFAMILY SSF54909 64 142 9.39E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 SUPERFAMILY SSF46785 3 63 2.85E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 SMART SM00344 4 110 2.6E-36 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 Gene3D G3DSA:1.10.10.10 1 57 5.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 Gene3D G3DSA:3.30.70.920 58 150 5.1E-19 T 14-10-2018 A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 3.2E-16 T 14-10-2018 A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.3E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.3E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_41630 91f953a500ccbc2425640aac0b3a28ef 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.3E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_01895 c375a0bff6960812dc9827c8090d8b76 224 Pfam PF02254 TrkA-N domain 13 128 9.4E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4R43_01895 c375a0bff6960812dc9827c8090d8b76 224 SUPERFAMILY SSF116726 138 222 9.42E-18 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_01895 c375a0bff6960812dc9827c8090d8b76 224 Gene3D G3DSA:3.30.70.1450 145 222 2.1E-17 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_01895 c375a0bff6960812dc9827c8090d8b76 224 SUPERFAMILY SSF51735 12 141 1.06E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_01895 c375a0bff6960812dc9827c8090d8b76 224 Pfam PF02080 TrkA-C domain 162 223 1.8E-12 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4R43_01895 c375a0bff6960812dc9827c8090d8b76 224 Gene3D G3DSA:3.40.50.720 10 144 7.5E-32 T 14-10-2018 A4R43_01805 23071538d5bab5986bf0aa412a0b76fd 307 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 115 1.5E-14 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_01805 23071538d5bab5986bf0aa412a0b76fd 307 SUPERFAMILY SSF55347 136 280 2.78E-16 T 14-10-2018 A4R43_01805 23071538d5bab5986bf0aa412a0b76fd 307 SUPERFAMILY SSF51735 2 126 4.56E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_01805 23071538d5bab5986bf0aa412a0b76fd 307 Gene3D G3DSA:3.30.360.10 137 307 1.1E-20 T 14-10-2018 A4R43_01805 23071538d5bab5986bf0aa412a0b76fd 307 Gene3D G3DSA:3.40.50.720 1 136 4.3E-26 T 14-10-2018 A4R43_41265 14ba5e599a40ba5e17d1abb194cccdfe 274 SUPERFAMILY SSF69593 30 237 6.8E-27 T 14-10-2018 A4R43_41265 14ba5e599a40ba5e17d1abb194cccdfe 274 SMART SM00563 56 176 1.9E-28 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_41265 14ba5e599a40ba5e17d1abb194cccdfe 274 Pfam PF01553 Acyltransferase 49 172 2.3E-16 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_31115 39867b80540cc3f6d87df856705dd89c 155 Pfam PF04186 FxsA cytoplasmic membrane protein 4 110 3.5E-31 T 14-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 A4R43_04965 fa27f697fac8b12605f3e004e68fcdb0 371 Gene3D G3DSA:3.20.20.70 4 367 1.2E-157 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_04965 fa27f697fac8b12605f3e004e68fcdb0 371 ProSitePatterns PS01054 Transaldolase signature 1. 43 51 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 A4R43_04965 fa27f697fac8b12605f3e004e68fcdb0 371 PIRSF PIRSF036915 1 371 2.4E-168 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4R43_04965 fa27f697fac8b12605f3e004e68fcdb0 371 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 360 5.3E-137 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4R43_04965 fa27f697fac8b12605f3e004e68fcdb0 371 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 17 361 3.4E-82 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 A4R43_04965 fa27f697fac8b12605f3e004e68fcdb0 371 SUPERFAMILY SSF51569 10 364 1.71E-75 T 14-10-2018 A4R43_04965 fa27f697fac8b12605f3e004e68fcdb0 371 Hamap MF_00493 Transaldolase [tal]. 1 371 155.316 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4R43_37535 dc88715b653d19007899f551271a15b1 320 SUPERFAMILY SSF52540 7 228 6.39E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37535 dc88715b653d19007899f551271a15b1 320 Gene3D G3DSA:3.40.50.300 2 241 2.6E-65 T 14-10-2018 A4R43_37535 dc88715b653d19007899f551271a15b1 320 SMART SM00382 32 215 2.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_37535 dc88715b653d19007899f551271a15b1 320 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 15 312 4.2E-107 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_37535 dc88715b653d19007899f551271a15b1 320 Pfam PF00005 ABC transporter 23 166 3.9E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_37535 dc88715b653d19007899f551271a15b1 320 Pfam PF13732 Domain of unknown function (DUF4162) 220 311 3.3E-8 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 A4R43_37535 dc88715b653d19007899f551271a15b1 320 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_23680 024cdbdbf5f1eb241c9dbd43a0f97c2a 143 Pfam PF14155 Domain of unknown function (DUF4307) 23 132 1.0E-29 T 14-10-2018 IPR025443 Protein of unknown function DUF4307 A4R43_13165 410adca44e48a0d9129000240efcc838 282 Gene3D G3DSA:3.20.20.70 1 282 4.1E-100 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_13165 410adca44e48a0d9129000240efcc838 282 Pfam PF00682 HMGL-like 3 272 5.5E-40 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4R43_13165 410adca44e48a0d9129000240efcc838 282 SUPERFAMILY SSF51569 3 278 4.58E-60 T 14-10-2018 A4R43_12535 92c3cdf0fbde30de4fdf2d89873a2dad 1621 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 197 236 1.6E-4 T 14-10-2018 IPR006530 YD repeat A4R43_12535 92c3cdf0fbde30de4fdf2d89873a2dad 1621 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 758 794 1.9E-5 T 14-10-2018 IPR006530 YD repeat A4R43_12535 92c3cdf0fbde30de4fdf2d89873a2dad 1621 Gene3D G3DSA:2.180.10.10 462 961 8.3E-25 T 14-10-2018 A4R43_12535 92c3cdf0fbde30de4fdf2d89873a2dad 1621 Pfam PF05593 RHS Repeat 758 793 1.1E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_12535 92c3cdf0fbde30de4fdf2d89873a2dad 1621 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 885 961 1.4E-18 T 14-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 A4R43_10290 de605c943c5235f521912df3b13c9000 265 SUPERFAMILY SSF51735 2 261 1.67E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_10290 de605c943c5235f521912df3b13c9000 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_10290 de605c943c5235f521912df3b13c9000 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 7.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_10290 de605c943c5235f521912df3b13c9000 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 7.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_10290 de605c943c5235f521912df3b13c9000 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_10290 de605c943c5235f521912df3b13c9000 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_10290 de605c943c5235f521912df3b13c9000 265 Gene3D G3DSA:3.40.50.720 1 264 3.3E-48 T 14-10-2018 A4R43_10290 de605c943c5235f521912df3b13c9000 265 Pfam PF00106 short chain dehydrogenase 6 184 9.0E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_27830 5273470c9a94f761586dead96fd73c5d 373 Pfam PF13358 DDE superfamily endonuclease 181 315 3.5E-13 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain A4R43_27830 5273470c9a94f761586dead96fd73c5d 373 SUPERFAMILY SSF46689 20 145 1.18E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_27830 5273470c9a94f761586dead96fd73c5d 373 Pfam PF13565 Homeodomain-like domain 61 142 4.5E-15 T 14-10-2018 A4R43_27830 5273470c9a94f761586dead96fd73c5d 373 SUPERFAMILY SSF53098 233 343 1.63E-8 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_27935 5273470c9a94f761586dead96fd73c5d 373 Pfam PF13358 DDE superfamily endonuclease 181 315 3.5E-13 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain A4R43_27935 5273470c9a94f761586dead96fd73c5d 373 SUPERFAMILY SSF46689 20 145 1.18E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_27935 5273470c9a94f761586dead96fd73c5d 373 Pfam PF13565 Homeodomain-like domain 61 142 4.5E-15 T 14-10-2018 A4R43_27935 5273470c9a94f761586dead96fd73c5d 373 SUPERFAMILY SSF53098 233 343 1.63E-8 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 SMART SM00345 33 90 1.7E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 SMART SM00866 110 250 1.3E-31 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 43 90 2.6E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 Gene3D G3DSA:3.40.1410.10 92 257 6.0E-43 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 3.7E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 3.7E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 Gene3D G3DSA:1.10.10.10 25 91 7.9E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 SUPERFAMILY SSF64288 78 256 2.04E-45 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 Pfam PF07702 UTRA domain 111 249 2.3E-31 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_15870 af27d0924553f4f05982b8e85d691b9e 257 SUPERFAMILY SSF46785 24 98 1.52E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26900 034bf5a27aad627f1a06afe62c18dea5 256 SUPERFAMILY SSF46785 15 89 2.5E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26900 034bf5a27aad627f1a06afe62c18dea5 256 SMART SM00346 15 105 7.3E-23 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_26900 034bf5a27aad627f1a06afe62c18dea5 256 Pfam PF09339 IclR helix-turn-helix domain 17 68 6.8E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_26900 034bf5a27aad627f1a06afe62c18dea5 256 Gene3D G3DSA:3.30.450.40 86 256 2.2E-41 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_26900 034bf5a27aad627f1a06afe62c18dea5 256 Gene3D G3DSA:1.10.10.10 13 85 8.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26900 034bf5a27aad627f1a06afe62c18dea5 256 SUPERFAMILY SSF55781 73 254 5.49E-37 T 14-10-2018 A4R43_26900 034bf5a27aad627f1a06afe62c18dea5 256 Pfam PF01614 Bacterial transcriptional regulator 136 250 2.1E-22 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_30455 b9bd4c74035e582fd62ea40c6a370637 304 Pfam PF13614 AAA domain 43 221 8.3E-58 T 14-10-2018 IPR025669 AAA domain A4R43_30455 b9bd4c74035e582fd62ea40c6a370637 304 Gene3D G3DSA:3.40.50.300 38 301 3.7E-76 T 14-10-2018 A4R43_30455 b9bd4c74035e582fd62ea40c6a370637 304 SUPERFAMILY SSF52540 43 296 5.57E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39135 0ef13c486fe7fc97a80d0b0913e86a4b 348 SUPERFAMILY SSF55347 114 282 8.34E-26 T 14-10-2018 A4R43_39135 0ef13c486fe7fc97a80d0b0913e86a4b 348 SUPERFAMILY SSF51735 1 141 8.27E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_39135 0ef13c486fe7fc97a80d0b0913e86a4b 348 Gene3D G3DSA:3.30.360.10 114 343 9.1E-103 T 14-10-2018 A4R43_39135 0ef13c486fe7fc97a80d0b0913e86a4b 348 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 107 1.2E-22 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_39135 0ef13c486fe7fc97a80d0b0913e86a4b 348 Gene3D G3DSA:3.40.50.720 1 319 9.1E-103 T 14-10-2018 A4R43_14820 8769397ff6ef38a5cbbe0c54a37b40d9 192 SUPERFAMILY SSF48498 78 185 1.83E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_14820 8769397ff6ef38a5cbbe0c54a37b40d9 192 Gene3D G3DSA:1.10.10.60 1 52 3.4E-15 T 14-10-2018 A4R43_14820 8769397ff6ef38a5cbbe0c54a37b40d9 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14820 8769397ff6ef38a5cbbe0c54a37b40d9 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14820 8769397ff6ef38a5cbbe0c54a37b40d9 192 SUPERFAMILY SSF46689 3 80 1.25E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14820 8769397ff6ef38a5cbbe0c54a37b40d9 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.0E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14820 8769397ff6ef38a5cbbe0c54a37b40d9 192 Gene3D G3DSA:1.10.357.10 53 192 6.4E-20 T 14-10-2018 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 592 37.689 T 14-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 Gene3D G3DSA:2.20.28.20 140 174 1.3E-144 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 SUPERFAMILY SSF52374 6 399 3.85E-89 T 14-10-2018 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 SUPERFAMILY SSF57770 140 174 1.05E-11 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 525 3.0E-144 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 4.9E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 253 264 4.9E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 399 410 4.9E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 4.9E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 4.9E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 4.9E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 Gene3D G3DSA:1.10.730.10 395 588 1.2E-36 T 14-10-2018 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 SUPERFAMILY SSF47323 400 581 2.24E-33 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 Pfam PF09334 tRNA synthetases class I (M) 6 411 2.2E-143 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_24090 305be7613a472f3b493e7beb083ef777 597 Gene3D G3DSA:3.40.50.620 6 394 1.3E-144 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 SUPERFAMILY SSF53383 16 392 4.59E-123 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 Pfam PF00202 Aminotransferase class-III 26 389 1.3E-108 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 Gene3D G3DSA:3.40.640.10 61 302 7.8E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 18 392 9.8E-142 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 17 395 66.802 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 220 257 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 PIRSF PIRSF000521 26 130 1.9E-8 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 PIRSF PIRSF000521 165 395 3.5E-30 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 PIRSF PIRSF000521 123 156 0.03 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_14315 e268faca04a480ee6d467e3a3aff29ec 398 Gene3D G3DSA:3.90.1150.10 28 384 7.8E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 Pfam PF00106 short chain dehydrogenase 372 560 3.1E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 371 547 0.0016 T 14-10-2018 A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 Gene3D G3DSA:3.40.50.720 359 618 1.2E-59 T 14-10-2018 A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 Pfam PF07993 Male sterility protein 6 229 3.2E-43 T 14-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 521 540 2.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 372 389 2.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 542 559 2.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 446 457 2.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 495 511 2.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 Gene3D G3DSA:3.40.50.720 2 358 1.3E-65 T 14-10-2018 A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 521 540 6.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 501 509 6.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 446 457 6.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 SUPERFAMILY SSF51735 367 588 1.67E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19110 ebc07ba643a50d9be9d40f7c312f9191 652 SUPERFAMILY SSF51735 2 281 6.25E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28370 dede9e6f419abab5884317d5f03501a2 387 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 385 7.0E-143 T 14-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain A4R43_28370 dede9e6f419abab5884317d5f03501a2 387 SUPERFAMILY SSF52440 175 283 1.06E-32 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_28370 dede9e6f419abab5884317d5f03501a2 387 SUPERFAMILY SSF56059 3 384 4.59E-72 T 14-10-2018 A4R43_28370 dede9e6f419abab5884317d5f03501a2 387 Gene3D G3DSA:3.30.1490.330 267 344 1.3E-24 T 14-10-2018 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 Gene3D G3DSA:3.30.300.20 179 257 1.9E-31 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 Pfam PF08529 NusA N-terminal domain 68 100 1.3E-6 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 Pfam PF08529 NusA N-terminal domain 6 60 1.2E-9 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 Gene3D G3DSA:2.40.50.140 105 178 6.4E-30 T 14-10-2018 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 Pfam PF13184 NusA-like KH domain 210 277 3.7E-25 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 SUPERFAMILY SSF54814 259 322 4.38E-17 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 Gene3D G3DSA:3.30.1480.10 1 99 8.2E-35 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 62 322 2.1E-100 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 SUPERFAMILY SSF50249 109 179 2.23E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 353 26.722 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 SUPERFAMILY SSF69705 4 99 1.19E-28 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 SMART SM00322 210 283 1.7 T 14-10-2018 IPR004087 K Homology domain GO:0003676 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 SMART SM00322 284 339 2.2 T 14-10-2018 IPR004087 K Homology domain GO:0003676 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 SUPERFAMILY SSF54814 180 258 2.94E-27 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 Gene3D G3DSA:3.30.300.20 258 327 1.0E-30 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_41050 21cb4595153ab03bd0695cff4631e890 364 SMART SM00316 110 180 8.0E-5 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Pfam PF00756 Putative esterase 1058 1252 6.8E-12 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 471 867 1.5E-116 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 SUPERFAMILY SSF53474 1040 1255 2.83E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 SUPERFAMILY SSF52777 176 423 2.33E-52 T 14-10-2018 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Gene3D G3DSA:3.40.50.12780 440 835 1.7E-125 T 14-10-2018 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Gene3D G3DSA:3.30.300.30 836 940 3.4E-28 T 14-10-2018 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 SMART SM00823 Phosphopantetheine attachment site 950 1018 1.6E-6 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Pfam PF00550 Phosphopantetheine attachment site 952 1014 1.3E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 SUPERFAMILY SSF56801 415 962 3.92E-138 T 14-10-2018 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Gene3D G3DSA:1.10.1200.10 942 1020 7.5E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Pfam PF13193 AMP-binding enzyme C-terminal domain 851 923 6.8E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Gene3D G3DSA:3.40.50.1820 1021 1257 9.9E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Gene3D G3DSA:3.30.559.30 172 417 4.5E-112 T 14-10-2018 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Pfam PF00501 AMP-binding enzyme 451 843 8.4E-88 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 SUPERFAMILY SSF52777 1 168 3.45E-39 T 14-10-2018 A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Pfam PF00668 Condensation domain 1 430 2.8E-79 T 14-10-2018 IPR001242 Condensation domain A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 SUPERFAMILY SSF47336 944 1014 1.57E-12 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02350 dc88e5346dc2553d6e168e3e3a937d7f 1261 Gene3D G3DSA:3.30.559.10 1 362 4.5E-112 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_37310 252a0ed0fdc45f37e180b83e3b1cd9d5 193 Gene3D G3DSA:2.30.110.10 14 192 3.8E-53 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_37310 252a0ed0fdc45f37e180b83e3b1cd9d5 193 SUPERFAMILY SSF50475 33 187 1.62E-46 T 14-10-2018 A4R43_37310 252a0ed0fdc45f37e180b83e3b1cd9d5 193 SMART SM00903 37 184 6.4E-53 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4R43_37310 252a0ed0fdc45f37e180b83e3b1cd9d5 193 Pfam PF01613 Flavin reductase like domain 37 186 3.0E-34 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 Gene3D G3DSA:2.40.33.10 71 167 5.6E-171 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 PRINTS PR01050 Pyruvate kinase family signature 216 242 5.8E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 PRINTS PR01050 Pyruvate kinase family signature 312 328 5.8E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 PRINTS PR01050 Pyruvate kinase family signature 243 267 5.8E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 PRINTS PR01050 Pyruvate kinase family signature 185 199 5.8E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 PRINTS PR01050 Pyruvate kinase family signature 60 76 5.8E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 PRINTS PR01050 Pyruvate kinase family signature 268 292 5.8E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 PRINTS PR01050 Pyruvate kinase family signature 293 311 5.8E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 SUPERFAMILY SSF52935 322 468 5.1E-36 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 214 226 - T 14-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 Gene3D G3DSA:3.20.20.60 3 334 5.6E-171 T 14-10-2018 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 466 2.3E-24 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 Gene3D G3DSA:3.40.1380.20 335 464 5.6E-171 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 Pfam PF00224 Pyruvate kinase, barrel domain 3 336 4.5E-123 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 467 3.5E-173 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 SUPERFAMILY SSF51621 2 337 2.06E-96 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_16295 04e8df0c5228cde6cb3f01f2f9e1fe61 474 SUPERFAMILY SSF50800 71 165 2.09E-27 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A4R43_38855 4426bcf6972eeae1768560f1bee28c7d 324 Pfam PF00924 Mechanosensitive ion channel 110 307 1.0E-37 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A4R43_38855 4426bcf6972eeae1768560f1bee28c7d 324 SUPERFAMILY SSF50182 151 208 1.67E-11 T 14-10-2018 IPR010920 LSM domain superfamily A4R43_38855 4426bcf6972eeae1768560f1bee28c7d 324 Gene3D G3DSA:2.30.30.60 167 216 2.8E-18 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A4R43_38855 4426bcf6972eeae1768560f1bee28c7d 324 SUPERFAMILY SSF82689 217 310 3.79E-11 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A4R43_38855 4426bcf6972eeae1768560f1bee28c7d 324 Gene3D G3DSA:3.30.70.100 218 306 1.4E-21 T 14-10-2018 A4R43_38855 4426bcf6972eeae1768560f1bee28c7d 324 SUPERFAMILY SSF82861 95 150 1.44E-11 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 282 9.9E-26 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 2.1E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 2.1E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 278 297 2.1E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 2.1E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 2.1E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 SUPERFAMILY SSF51905 1 287 6.2E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 Gene3D G3DSA:3.50.50.60 114 224 2.8E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.6E-14 T 14-10-2018 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 2.6E-14 T 14-10-2018 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 267 2.6E-14 T 14-10-2018 A4R43_38640 51b4fa171d7c8aa2e9a06b4499809f80 308 Gene3D G3DSA:3.50.50.60 2 291 2.8E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_39495 06772de85b14fd2f5b64045225f94977 243 Gene3D G3DSA:3.40.50.1400 127 238 1.8E-19 T 14-10-2018 A4R43_39495 06772de85b14fd2f5b64045225f94977 243 Gene3D G3DSA:3.40.50.1400 2 121 9.3E-29 T 14-10-2018 A4R43_39495 06772de85b14fd2f5b64045225f94977 243 SUPERFAMILY SSF53800 3 235 1.31E-39 T 14-10-2018 A4R43_39495 06772de85b14fd2f5b64045225f94977 243 Pfam PF01903 CbiX 136 229 3.4E-10 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A4R43_39495 06772de85b14fd2f5b64045225f94977 243 Pfam PF01903 CbiX 9 111 7.6E-21 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A4R43_15440 f53106957a1266f54421ef36a74a754c 145 SUPERFAMILY SSF52821 18 123 6.81E-22 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_15440 f53106957a1266f54421ef36a74a754c 145 SMART SM00450 22 119 1.9E-11 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_15440 f53106957a1266f54421ef36a74a754c 145 Pfam PF00581 Rhodanese-like domain 22 115 4.1E-12 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_15440 f53106957a1266f54421ef36a74a754c 145 Gene3D G3DSA:3.40.250.10 4 122 3.0E-26 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_36590 fb3584a1acf3380df75b93c159e4ec0e 394 SUPERFAMILY SSF103473 6 384 1.44E-30 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_36590 fb3584a1acf3380df75b93c159e4ec0e 394 Pfam PF07690 Major Facilitator Superfamily 13 314 2.9E-15 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_36590 fb3584a1acf3380df75b93c159e4ec0e 394 Gene3D G3DSA:1.20.1250.20 191 379 6.9E-19 T 14-10-2018 A4R43_36590 fb3584a1acf3380df75b93c159e4ec0e 394 Gene3D G3DSA:1.20.1250.20 3 187 2.5E-8 T 14-10-2018 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 285 2.9E-47 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 SUPERFAMILY SSF55124 496 631 1.24E-24 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 SUPERFAMILY SSF51905 3 134 3.6E-15 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 SUPERFAMILY SSF51905 101 307 1.7E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 4 791 0.0 T 14-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 PIRSF PIRSF037149 1 825 0.0 T 14-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 4.9E-17 T 14-10-2018 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 4.9E-17 T 14-10-2018 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 4.9E-17 T 14-10-2018 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 4.9E-17 T 14-10-2018 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 622 758 5.3E-18 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Gene3D G3DSA:1.10.10.1100 416 469 1.7E-8 T 14-10-2018 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Gene3D G3DSA:3.50.50.60 106 244 2.2E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Gene3D G3DSA:3.30.413.10 621 780 2.1E-34 T 14-10-2018 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 550 611 3.0E-11 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Pfam PF04324 BFD-like [2Fe-2S] binding domain 417 465 6.5E-12 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Pfam PF04324 BFD-like [2Fe-2S] binding domain 479 523 1.0E-4 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 SUPERFAMILY SSF56014 623 797 1.44E-50 T 14-10-2018 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 Gene3D G3DSA:3.50.50.60 5 281 2.2E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 669 685 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 PRINTS PR00397 Sirohaem Fe-binding site signature 669 687 6.4E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_35905 41f9bfb19e4671dfeeecc984cf8615d9 833 PRINTS PR00397 Sirohaem Fe-binding site signature 626 644 6.4E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 SUPERFAMILY SSF46894 138 215 7.14E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 SMART SM00448 2 116 6.1E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 Gene3D G3DSA:3.40.50.12740 2 215 8.4E-63 T 14-10-2018 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 SUPERFAMILY SSF52172 2 133 4.27E-29 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.5E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 SMART SM00421 152 209 3.7E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25065 1b41795da0c71d3c3a6a247b69b19f03 216 Pfam PF00072 Response regulator receiver domain 4 116 5.9E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 SUPERFAMILY SSF46785 4 56 5.24E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 Pfam PF13404 AsnC-type helix-turn-helix domain 1 41 6.4E-9 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 175 191 1.6E-5 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 202 221 1.6E-5 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 191 202 1.6E-5 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 SMART SM00344 180 280 1.9E-4 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 SUPERFAMILY SSF54909 234 312 9.39E-10 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 Gene3D G3DSA:1.10.10.10 1 48 7.8E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 Gene3D G3DSA:3.30.70.920 65 138 2.7E-11 T 14-10-2018 A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 Gene3D G3DSA:3.30.70.920 227 315 1.4E-12 T 14-10-2018 A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 SUPERFAMILY SSF46785 176 237 1.38E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 SUPERFAMILY SSF54909 65 137 3.35E-10 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 Pfam PF01037 Lrp/AsnC ligand binding domain 66 136 1.1E-8 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 Pfam PF01037 Lrp/AsnC ligand binding domain 242 310 7.9E-7 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_06985 91aba7d03f09bfeeeb52ab979666b769 325 Gene3D G3DSA:1.10.10.10 177 223 2.8E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07030 c77edaa99ddf6aec3db84c235784d52b 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 259 6.3E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_07030 c77edaa99ddf6aec3db84c235784d52b 275 Gene3D G3DSA:1.10.3720.10 2 262 2.5E-59 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_07030 c77edaa99ddf6aec3db84c235784d52b 275 SUPERFAMILY SSF161098 4 275 3.66E-67 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 240 1.2E-51 T 14-10-2018 A4R43_15945 d499f727337f1d575b0c273555732062 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_15945 d499f727337f1d575b0c273555732062 258 SUPERFAMILY SSF51735 10 240 1.18E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.9E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.9E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.9E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15945 d499f727337f1d575b0c273555732062 258 Gene3D G3DSA:3.40.50.720 7 257 9.2E-64 T 14-10-2018 A4R43_18380 e92820624928a70585558b89b95c62b3 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.993 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A4R43_18380 e92820624928a70585558b89b95c62b3 185 Gene3D G3DSA:1.10.132.20 1 32 3.7E-5 T 14-10-2018 A4R43_18380 e92820624928a70585558b89b95c62b3 185 Gene3D G3DSA:3.30.1360.40 33 99 6.1E-30 T 14-10-2018 A4R43_18380 e92820624928a70585558b89b95c62b3 185 Pfam PF01765 Ribosome recycling factor 21 183 3.2E-62 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A4R43_18380 e92820624928a70585558b89b95c62b3 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.1E-64 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A4R43_18380 e92820624928a70585558b89b95c62b3 185 Gene3D G3DSA:1.10.132.20 100 185 4.0E-27 T 14-10-2018 A4R43_18380 e92820624928a70585558b89b95c62b3 185 SUPERFAMILY SSF55194 3 184 1.7E-69 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 Gene3D G3DSA:1.10.390.60 224 438 1.2E-41 T 14-10-2018 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 Gene3D G3DSA:2.60.40.1730 26 211 9.1E-24 T 14-10-2018 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 SUPERFAMILY SSF55486 225 442 2.44E-55 T 14-10-2018 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 Pfam PF01433 Peptidase family M1 domain 248 434 1.7E-29 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 SUPERFAMILY SSF63737 16 209 5.62E-36 T 14-10-2018 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 146 161 1.6E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 296 311 1.6E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 327 1.6E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_14125 62ca17adc6d29b4ae68f8acc825ad887 445 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 193 208 1.6E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_31205 9bbe30cf3aec832f119cde3b91e79595 185 Gene3D G3DSA:3.40.430.10 2 184 1.2E-43 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_31205 9bbe30cf3aec832f119cde3b91e79595 185 SUPERFAMILY SSF53597 1 185 1.31E-32 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_31205 9bbe30cf3aec832f119cde3b91e79595 185 Pfam PF01872 RibD C-terminal domain 2 180 3.2E-29 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 SMART SM00388 237 301 2.7E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 456 2.8E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 299 7.9E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 Gene3D G3DSA:3.30.565.10 310 458 1.5E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 Pfam PF00672 HAMP domain 184 230 1.0E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 SUPERFAMILY SSF47384 220 299 4.32E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 Gene3D G3DSA:1.10.287.130 188 302 7.8E-22 T 14-10-2018 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 SMART SM00387 350 458 5.3E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 SUPERFAMILY SSF55874 312 456 1.1E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 2.9E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 2.9E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 2.9E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_11055 c34ab87040f6b64aea21516252fbae08 459 SMART SM00304 184 236 2.8E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_31085 0be1823f6fab2dccaea87afc43ff3ea0 429 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 14 428 2.4E-121 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_31085 0be1823f6fab2dccaea87afc43ff3ea0 429 Pfam PF00108 Thiolase, N-terminal domain 12 279 1.0E-52 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_31085 0be1823f6fab2dccaea87afc43ff3ea0 429 SUPERFAMILY SSF53901 12 286 1.3E-58 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_31085 0be1823f6fab2dccaea87afc43ff3ea0 429 SUPERFAMILY SSF53901 301 429 1.81E-30 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_31085 0be1823f6fab2dccaea87afc43ff3ea0 429 Pfam PF02803 Thiolase, C-terminal domain 289 429 3.1E-32 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_31085 0be1823f6fab2dccaea87afc43ff3ea0 429 Gene3D G3DSA:3.40.47.10 2 429 7.1E-106 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_31085 0be1823f6fab2dccaea87afc43ff3ea0 429 PIRSF PIRSF000429 6 429 3.5E-106 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_37855 b2e30c206f6e100beebf472473177214 551 SUPERFAMILY SSF52540 336 547 2.23E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37855 b2e30c206f6e100beebf472473177214 551 Pfam PF00664 ABC transporter transmembrane region 21 288 3.2E-24 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_37855 b2e30c206f6e100beebf472473177214 551 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_37855 b2e30c206f6e100beebf472473177214 551 Gene3D G3DSA:3.40.50.300 327 550 3.2E-46 T 14-10-2018 A4R43_37855 b2e30c206f6e100beebf472473177214 551 SUPERFAMILY SSF90123 7 315 1.26E-55 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_37855 b2e30c206f6e100beebf472473177214 551 Pfam PF00005 ABC transporter 343 481 9.2E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_37855 b2e30c206f6e100beebf472473177214 551 Gene3D G3DSA:1.20.1560.10 4 319 5.5E-56 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 Pfam PF00067 Cytochrome P450 264 359 1.8E-19 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00385 P450 superfamily signature 264 275 4.9E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00385 P450 superfamily signature 340 351 4.9E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00385 P450 superfamily signature 331 340 4.9E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00385 P450 superfamily signature 237 254 4.9E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 SUPERFAMILY SSF48264 18 391 3.67E-83 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00359 B-class P450 signature 158 173 2.8E-50 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00359 B-class P450 signature 94 105 2.8E-50 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00359 B-class P450 signature 331 340 2.8E-50 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00359 B-class P450 signature 141 157 2.8E-50 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00359 B-class P450 signature 340 351 2.8E-50 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00359 B-class P450 signature 195 217 2.8E-50 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00359 B-class P450 signature 282 309 2.8E-50 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 PRINTS PR00359 B-class P450 signature 310 325 2.8E-50 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38470 3e4f774cc90f832a60e18bd8216ddb52 391 Gene3D G3DSA:1.10.630.10 13 391 5.1E-107 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_31935 68cb7f56226c0db1ce8c7b76e7f98a5e 356 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 341 4.9E-30 T 14-10-2018 IPR010918 PurM-like, C-terminal domain A4R43_31935 68cb7f56226c0db1ce8c7b76e7f98a5e 356 SUPERFAMILY SSF55326 7 168 3.14E-43 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4R43_31935 68cb7f56226c0db1ce8c7b76e7f98a5e 356 SUPERFAMILY SSF56042 173 340 6.43E-52 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4R43_31935 68cb7f56226c0db1ce8c7b76e7f98a5e 356 Pfam PF00586 AIR synthase related protein, N-terminal domain 62 165 1.4E-15 T 14-10-2018 IPR016188 PurM-like, N-terminal domain A4R43_31935 68cb7f56226c0db1ce8c7b76e7f98a5e 356 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 349 41.027 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31935 68cb7f56226c0db1ce8c7b76e7f98a5e 356 Gene3D G3DSA:3.30.1330.10 5 171 5.3E-58 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4R43_31935 68cb7f56226c0db1ce8c7b76e7f98a5e 356 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 337 1.2E-132 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31935 68cb7f56226c0db1ce8c7b76e7f98a5e 356 Gene3D G3DSA:3.90.650.10 173 349 4.1E-58 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 Gene3D G3DSA:3.40.190.10 104 278 9.9E-11 T 14-10-2018 A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 Gene3D G3DSA:1.10.10.10 1 86 1.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 SUPERFAMILY SSF46785 2 82 2.06E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.0E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 SUPERFAMILY SSF53850 103 294 3.33E-18 T 14-10-2018 A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 Pfam PF03466 LysR substrate binding domain 104 291 1.8E-12 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_08725 17990b4e150dd5e236368b4082a3e1ab 305 Gene3D G3DSA:3.40.190.10 162 266 9.9E-11 T 14-10-2018 A4R43_00605 d0ae22d9cb3af4b10beadfe7ecb375ea 431 Gene3D G3DSA:3.40.640.10 58 322 3.5E-141 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_00605 d0ae22d9cb3af4b10beadfe7ecb375ea 431 Pfam PF00202 Aminotransferase class-III 23 427 7.1E-92 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_00605 d0ae22d9cb3af4b10beadfe7ecb375ea 431 SUPERFAMILY SSF53383 6 429 5.27E-117 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_00605 d0ae22d9cb3af4b10beadfe7ecb375ea 431 Gene3D G3DSA:3.90.1150.10 29 422 3.5E-141 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_00605 d0ae22d9cb3af4b10beadfe7ecb375ea 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_00605 d0ae22d9cb3af4b10beadfe7ecb375ea 431 PIRSF PIRSF000521 20 127 3.1E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_00605 d0ae22d9cb3af4b10beadfe7ecb375ea 431 PIRSF PIRSF000521 122 430 9.7E-28 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_18450 334d22fadb90d29a35bde0c5a915b990 251 Gene3D G3DSA:1.10.1270.20 164 251 8.7E-30 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4R43_18450 334d22fadb90d29a35bde0c5a915b990 251 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 221 9.4E-70 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4R43_18450 334d22fadb90d29a35bde0c5a915b990 251 SUPERFAMILY SSF75217 1 234 9.81E-90 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_18450 334d22fadb90d29a35bde0c5a915b990 251 Gene3D G3DSA:3.40.1280.10 1 163 6.5E-68 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_18450 334d22fadb90d29a35bde0c5a915b990 251 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 227 2.2E-76 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4R43_18450 334d22fadb90d29a35bde0c5a915b990 251 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 251 104.044 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4R43_18450 334d22fadb90d29a35bde0c5a915b990 251 PIRSF PIRSF000386 1 247 3.7E-93 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4R43_09090 5f5381f3a7525a429d7fb549ad0e2548 974 Gene3D G3DSA:2.60.120.260 801 969 8.2E-60 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_09090 5f5381f3a7525a429d7fb549ad0e2548 974 Gene3D G3DSA:2.60.40.1180 551 660 2.7E-22 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta A4R43_09090 5f5381f3a7525a429d7fb549ad0e2548 974 Pfam PF12905 Endo-alpha-N-acetylgalactosaminidase 267 537 1.6E-125 T 14-10-2018 IPR025706 Endo-alpha-N-acetylgalactosaminidase GO:0033926 A4R43_09090 5f5381f3a7525a429d7fb549ad0e2548 974 Gene3D G3DSA:3.20.20.80 281 550 2.2E-118 T 14-10-2018 A4R43_09090 5f5381f3a7525a429d7fb549ad0e2548 974 Gene3D G3DSA:2.60.120.260 668 800 8.5E-34 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_09090 5f5381f3a7525a429d7fb549ad0e2548 974 Pfam PF17451 Glycosyl hydrolase 101 beta sandwich domain 544 633 1.1E-16 T 14-10-2018 IPR035364 Glycosyl hydrolase 101, beta-sandwich domain A4R43_09090 5f5381f3a7525a429d7fb549ad0e2548 974 Gene3D G3DSA:2.70.98.10 26 278 3.8E-68 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_09355 45456f112ddde159bb8812d3aab8a264 194 Gene3D G3DSA:3.40.430.10 2 190 1.6E-41 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_09355 45456f112ddde159bb8812d3aab8a264 194 Pfam PF01872 RibD C-terminal domain 2 187 7.4E-22 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_09355 45456f112ddde159bb8812d3aab8a264 194 SUPERFAMILY SSF53597 2 192 9.69E-33 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_09075 5bd96566418830fc7049774c6f2683db 527 Gene3D G3DSA:1.10.10.2840 394 527 1.3E-18 T 14-10-2018 A4R43_09075 5bd96566418830fc7049774c6f2683db 527 Pfam PF13556 PucR C-terminal helix-turn-helix domain 465 521 5.2E-16 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 SUPERFAMILY SSF51735 5 227 8.3E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 Gene3D G3DSA:3.40.50.720 5 259 4.1E-53 T 14-10-2018 A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.6E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.6E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.6E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.6E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 8.6E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07550 4ce40c97ede04d34d6294746acbd7ee5 268 Pfam PF00106 short chain dehydrogenase 10 195 2.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09820 18660738e9dc7aaf88ad7af59d01a49f 368 Gene3D G3DSA:3.30.565.10 242 365 3.6E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_09820 18660738e9dc7aaf88ad7af59d01a49f 368 SUPERFAMILY SSF55874 254 365 3.01E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_09820 18660738e9dc7aaf88ad7af59d01a49f 368 Pfam PF07730 Histidine kinase 171 236 1.2E-14 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_09820 18660738e9dc7aaf88ad7af59d01a49f 368 SMART SM00387 274 366 0.0017 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 Gene3D G3DSA:1.10.630.10 2 390 1.5E-127 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 338 349 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 144 159 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 280 307 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 80 91 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 127 143 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 181 203 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 262 273 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 329 338 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00359 B-class P450 signature 308 323 9.2E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00385 P450 superfamily signature 227 244 1.9E-9 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00385 P450 superfamily signature 338 349 1.9E-9 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00385 P450 superfamily signature 329 338 1.9E-9 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 PRINTS PR00385 P450 superfamily signature 262 273 1.9E-9 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 Pfam PF00067 Cytochrome P450 76 358 9.0E-26 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 331 340 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_34825 df5622e800b9596c7bf8408298e3d813 390 SUPERFAMILY SSF48264 5 389 1.1E-96 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_16945 ebe52daff5d040ad5acf0fa31d8ac508 622 Gene3D G3DSA:3.50.30.80 421 569 5.0E-51 T 14-10-2018 A4R43_16945 ebe52daff5d040ad5acf0fa31d8ac508 622 Hamap MF_02094 Phosphogluconate dehydratase [edd]. 4 605 58.227 T 14-10-2018 A4R43_16945 ebe52daff5d040ad5acf0fa31d8ac508 622 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_16945 ebe52daff5d040ad5acf0fa31d8ac508 622 SUPERFAMILY SSF143975 4 420 9.68E-145 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_16945 ebe52daff5d040ad5acf0fa31d8ac508 622 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 157 167 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_16945 ebe52daff5d040ad5acf0fa31d8ac508 622 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 5 604 2.1E-291 T 14-10-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 A4R43_16945 ebe52daff5d040ad5acf0fa31d8ac508 622 Pfam PF00920 Dehydratase family 68 601 1.4E-161 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_16945 ebe52daff5d040ad5acf0fa31d8ac508 622 SUPERFAMILY SSF52016 421 603 8.63E-56 T 14-10-2018 A4R43_24995 1b93c83793dbf359b23b8e2893201568 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 228 3.0E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_24995 1b93c83793dbf359b23b8e2893201568 235 Pfam PF00072 Response regulator receiver domain 8 116 4.9E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_24995 1b93c83793dbf359b23b8e2893201568 235 Gene3D G3DSA:1.10.10.10 126 234 8.1E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_24995 1b93c83793dbf359b23b8e2893201568 235 SMART SM00862 154 229 9.8E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_24995 1b93c83793dbf359b23b8e2893201568 235 SUPERFAMILY SSF52172 4 132 9.96E-45 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_24995 1b93c83793dbf359b23b8e2893201568 235 Gene3D G3DSA:3.40.50.2300 1 125 1.2E-40 T 14-10-2018 A4R43_24995 1b93c83793dbf359b23b8e2893201568 235 SMART SM00448 6 116 4.4E-48 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_24995 1b93c83793dbf359b23b8e2893201568 235 SUPERFAMILY SSF46894 136 229 3.12E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_23045 82266f2aa0c877c29a931a01e7d601fe 184 Pfam PF02575 YbaB/EbfC DNA-binding family 17 99 2.0E-9 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_23045 82266f2aa0c877c29a931a01e7d601fe 184 SUPERFAMILY SSF82607 18 101 8.76E-9 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_23045 82266f2aa0c877c29a931a01e7d601fe 184 Gene3D G3DSA:3.30.1310.10 6 106 1.4E-7 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_12300 ea4263083ab0536f2eb8d8696b745450 452 SUPERFAMILY SSF56112 25 265 2.97E-30 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_12300 ea4263083ab0536f2eb8d8696b745450 452 Gene3D G3DSA:1.10.510.10 99 273 4.8E-26 T 14-10-2018 A4R43_12300 ea4263083ab0536f2eb8d8696b745450 452 Pfam PF00069 Protein kinase domain 25 260 3.8E-17 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_12300 ea4263083ab0536f2eb8d8696b745450 452 SMART SM00220 20 278 5.7E-9 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_21535 6d280ee01e5a93d4abb7a0cff4b0ccf5 381 SUPERFAMILY SSF47203 216 373 1.47E-11 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_21535 6d280ee01e5a93d4abb7a0cff4b0ccf5 381 Gene3D G3DSA:1.10.540.10 1 107 7.3E-30 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_21535 6d280ee01e5a93d4abb7a0cff4b0ccf5 381 Gene3D G3DSA:1.20.140.10 202 378 3.5E-36 T 14-10-2018 A4R43_21535 6d280ee01e5a93d4abb7a0cff4b0ccf5 381 Gene3D G3DSA:2.40.110.10 108 196 1.3E-28 T 14-10-2018 A4R43_21535 6d280ee01e5a93d4abb7a0cff4b0ccf5 381 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 225 357 1.5E-25 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4R43_21535 6d280ee01e5a93d4abb7a0cff4b0ccf5 381 PIRSF PIRSF016578 1 380 6.2E-116 T 14-10-2018 A4R43_21535 6d280ee01e5a93d4abb7a0cff4b0ccf5 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 92 4.1E-5 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_21535 6d280ee01e5a93d4abb7a0cff4b0ccf5 381 SUPERFAMILY SSF56645 11 196 2.36E-33 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_07040 97be44eeeee3d6bd4b2be9fdfb5a314c 387 Gene3D G3DSA:1.10.4080.10 2 361 1.6E-40 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_07040 97be44eeeee3d6bd4b2be9fdfb5a314c 387 SUPERFAMILY SSF101478 3 347 2.09E-40 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_07040 97be44eeeee3d6bd4b2be9fdfb5a314c 387 Pfam PF03747 ADP-ribosylglycohydrolase 11 336 1.4E-43 T 14-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 A4R43_30415 877e31d89ffa1875af0afa493f30965d 387 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 361 1.0E-17 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A4R43_30415 877e31d89ffa1875af0afa493f30965d 387 Gene3D G3DSA:1.20.1050.90 120 327 2.4E-92 T 14-10-2018 A4R43_30415 877e31d89ffa1875af0afa493f30965d 387 SUPERFAMILY SSF52540 2 349 3.8E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30415 877e31d89ffa1875af0afa493f30965d 387 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 14-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A4R43_30415 877e31d89ffa1875af0afa493f30965d 387 ProSitePatterns PS00618 RecF protein signature 2. 328 346 - T 14-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A4R43_30415 877e31d89ffa1875af0afa493f30965d 387 Gene3D G3DSA:3.40.50.300 6 360 2.4E-92 T 14-10-2018 A4R43_30415 877e31d89ffa1875af0afa493f30965d 387 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 377 3.9E-117 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A4R43_30415 877e31d89ffa1875af0afa493f30965d 387 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 387 94.186 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A4R43_08130 8e1018184b179a8864b0f5a516b1bc8a 424 SUPERFAMILY SSF103473 3 404 2.62E-37 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08130 8e1018184b179a8864b0f5a516b1bc8a 424 Pfam PF07690 Major Facilitator Superfamily 8 347 7.5E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_08130 8e1018184b179a8864b0f5a516b1bc8a 424 Gene3D G3DSA:1.20.1250.20 2 411 6.1E-36 T 14-10-2018 A4R43_03605 1377c3a8dab8df8181c9f18352298ca1 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 276 6.3E-46 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_03605 1377c3a8dab8df8181c9f18352298ca1 308 Gene3D G3DSA:3.40.50.720 18 299 1.2E-105 T 14-10-2018 A4R43_03605 1377c3a8dab8df8181c9f18352298ca1 308 Gene3D G3DSA:3.40.50.720 96 279 1.2E-105 T 14-10-2018 A4R43_03605 1377c3a8dab8df8181c9f18352298ca1 308 SUPERFAMILY SSF52283 1 130 2.46E-29 T 14-10-2018 A4R43_03605 1377c3a8dab8df8181c9f18352298ca1 308 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4R43_03605 1377c3a8dab8df8181c9f18352298ca1 308 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 28 307 1.3E-20 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_03605 1377c3a8dab8df8181c9f18352298ca1 308 SUPERFAMILY SSF51735 96 277 9.51E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_10805 6804f97c8cfecb556fccac9383008c54 354 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 60 311 5.2E-49 T 14-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A4R43_10805 6804f97c8cfecb556fccac9383008c54 354 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 173 182 - T 14-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 A4R43_10805 6804f97c8cfecb556fccac9383008c54 354 Gene3D G3DSA:3.20.20.80 43 347 6.1E-91 T 14-10-2018 A4R43_10805 6804f97c8cfecb556fccac9383008c54 354 SUPERFAMILY SSF51445 43 350 4.36E-77 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_16135 92d298acc87dadddd86214270239a307 261 Pfam PF13359 DDE superfamily endonuclease 104 255 5.7E-27 T 14-10-2018 IPR027806 Harbinger transposase-derived nuclease domain A4R43_16135 92d298acc87dadddd86214270239a307 261 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 85 4.0E-16 T 14-10-2018 IPR027805 Transposase, Helix-turn-helix domain A4R43_19235 8ee427c229d6ca6622990e9a41a3fe0e 307 Pfam PF00294 pfkB family carbohydrate kinase 5 299 2.2E-46 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_19235 8ee427c229d6ca6622990e9a41a3fe0e 307 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 2 307 3.5E-105 T 14-10-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 A4R43_19235 8ee427c229d6ca6622990e9a41a3fe0e 307 SUPERFAMILY SSF53613 3 307 3.74E-71 T 14-10-2018 IPR029056 Ribokinase-like A4R43_19235 8ee427c229d6ca6622990e9a41a3fe0e 307 Gene3D G3DSA:3.40.1190.20 4 289 1.2E-90 T 14-10-2018 IPR029056 Ribokinase-like A4R43_19235 8ee427c229d6ca6622990e9a41a3fe0e 307 Gene3D G3DSA:2.20.150.10 9 104 1.2E-90 T 14-10-2018 IPR023314 5-Dehydro-2-deoxygluconokinase-like superfamily KEGG: 00562+2.7.1.92 A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 SUPERFAMILY SSF63867 354 431 4.32E-18 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 Pfam PF00994 Probable molybdopterin binding domain 207 344 6.1E-19 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 Gene3D G3DSA:2.170.190.11 72 167 2.3E-91 T 14-10-2018 A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 Gene3D G3DSA:3.40.980.10 201 344 2.3E-91 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 203 341 2.4E-25 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 SMART SM00852 206 345 1.8E-27 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 SUPERFAMILY SSF63882 30 202 3.14E-44 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 Gene3D G3DSA:2.40.340.10 356 428 1.4E-20 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 SUPERFAMILY SSF53218 203 350 8.25E-33 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 Pfam PF03454 MoeA C-terminal region (domain IV) 359 431 4.7E-20 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 Gene3D G3DSA:3.90.105.10 50 200 2.3E-91 T 14-10-2018 A4R43_24945 fcedde8f9e6b77a40864fcdf95ac86fd 435 Pfam PF03453 MoeA N-terminal region (domain I and II) 31 193 2.7E-38 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_02125 808c9f854d2c4577c30b6c7076adbd36 259 SUPERFAMILY SSF55781 89 251 5.23E-27 T 14-10-2018 A4R43_02125 808c9f854d2c4577c30b6c7076adbd36 259 SUPERFAMILY SSF46785 13 82 4.68E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02125 808c9f854d2c4577c30b6c7076adbd36 259 SMART SM00346 13 102 6.6E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_02125 808c9f854d2c4577c30b6c7076adbd36 259 Gene3D G3DSA:1.10.10.10 2 73 2.7E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02125 808c9f854d2c4577c30b6c7076adbd36 259 Pfam PF09339 IclR helix-turn-helix domain 15 64 5.5E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_02125 808c9f854d2c4577c30b6c7076adbd36 259 Gene3D G3DSA:3.30.450.40 78 257 2.6E-38 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_02125 808c9f854d2c4577c30b6c7076adbd36 259 Pfam PF01614 Bacterial transcriptional regulator 130 251 2.8E-7 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_12660 1d89063c35541804a7cdaa426509928d 580 Gene3D G3DSA:3.30.300.30 461 580 3.1E-35 T 14-10-2018 A4R43_12660 1d89063c35541804a7cdaa426509928d 580 Gene3D G3DSA:3.40.50.12780 9 459 1.3E-133 T 14-10-2018 A4R43_12660 1d89063c35541804a7cdaa426509928d 580 SUPERFAMILY SSF56801 10 570 1.57E-98 T 14-10-2018 A4R43_12660 1d89063c35541804a7cdaa426509928d 580 Pfam PF00501 AMP-binding enzyme 17 466 6.1E-77 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 1.4E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 1.4E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 1.4E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 1.4E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 Pfam PF12802 MarR family 48 110 1.0E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 Gene3D G3DSA:1.10.10.10 2 160 3.6E-41 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 SUPERFAMILY SSF46785 9 159 2.22E-37 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03590 a51f7cd105ad65c12526b2e5d2a60df7 164 SMART SM00347 43 146 3.6E-22 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 2.3E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 1.1E-24 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 Gene3D G3DSA:2.40.110.10 122 235 4.9E-43 T 14-10-2018 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 Gene3D G3DSA:1.10.540.10 2 121 2.9E-27 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 SUPERFAMILY SSF47203 229 377 1.21E-41 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 Gene3D G3DSA:1.20.140.10 236 378 2.5E-38 T 14-10-2018 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 SUPERFAMILY SSF56645 7 242 1.7E-75 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_01625 ebfe000995566bccd62ba5f6d96d0b33 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 377 8.2E-36 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 Gene3D G3DSA:3.40.50.1820 227 310 1.2E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 Gene3D G3DSA:3.40.50.1820 31 200 5.0E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 199 272 9.7E-12 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 50 194 1.5E-32 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 SUPERFAMILY SSF53474 29 322 1.55E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 46 213 6.9E-35 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 300 476 1.3E-38 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 SUPERFAMILY SSF49785 315 478 4.25E-38 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 Gene3D G3DSA:2.60.120.260 316 483 1.9E-39 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 SMART SM00939 287 492 1.6E-42 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_07325 afcc446b680c9bfbb47584584a05a2a9 497 Gene3D G3DSA:1.10.3020.10 202 226 1.2E-17 T 14-10-2018 A4R43_23660 a2c9ca103f3a788507de851215860fbd 456 Pfam PF08242 Methyltransferase domain 278 379 3.5E-12 T 14-10-2018 IPR013217 Methyltransferase type 12 A4R43_23660 a2c9ca103f3a788507de851215860fbd 456 SUPERFAMILY SSF53335 265 419 3.5E-21 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_23660 a2c9ca103f3a788507de851215860fbd 456 Gene3D G3DSA:3.30.1610.20 1 225 5.6E-100 T 14-10-2018 IPR038546 Hen1, N-terminal domain superfamily A4R43_23660 a2c9ca103f3a788507de851215860fbd 456 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 2 452 2.0E-204 T 14-10-2018 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial A4R43_23660 a2c9ca103f3a788507de851215860fbd 456 Gene3D G3DSA:3.40.50.150 247 455 1.7E-68 T 14-10-2018 A4R43_23660 a2c9ca103f3a788507de851215860fbd 456 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 236 6.1E-108 T 14-10-2018 IPR024740 Hen1, N-terminal A4R43_26920 3172fcada0e92b0b50e30bb3e51f32e0 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 1.6E-7 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_26920 3172fcada0e92b0b50e30bb3e51f32e0 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 3.5E-5 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_26920 3172fcada0e92b0b50e30bb3e51f32e0 174 Gene3D G3DSA:2.160.10.10 1 172 1.1E-53 T 14-10-2018 A4R43_26920 3172fcada0e92b0b50e30bb3e51f32e0 174 SUPERFAMILY SSF51161 2 166 2.77E-43 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_16400 5e9e1b17dc3baede81e72b378abfe64f 323 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_16400 5e9e1b17dc3baede81e72b378abfe64f 323 SUPERFAMILY SSF52540 8 230 6.2E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16400 5e9e1b17dc3baede81e72b378abfe64f 323 Pfam PF00005 ABC transporter 25 168 2.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_16400 5e9e1b17dc3baede81e72b378abfe64f 323 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 312 8.2E-107 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_16400 5e9e1b17dc3baede81e72b378abfe64f 323 SMART SM00382 34 225 1.7E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_16400 5e9e1b17dc3baede81e72b378abfe64f 323 Gene3D G3DSA:3.40.50.300 4 235 1.0E-66 T 14-10-2018 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 36 594 54.773 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 275 288 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 72 88 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 Gene3D G3DSA:3.20.20.70 43 418 8.0E-159 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 SUPERFAMILY SSF51569 54 362 1.7E-97 T 14-10-2018 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 Pfam PF08502 LeuA allosteric (dimerisation) domain 464 592 9.1E-32 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 Gene3D G3DSA:3.30.160.270 481 594 1.6E-37 T 14-10-2018 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 SUPERFAMILY SSF89000 430 480 7.85E-14 T 14-10-2018 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 SUPERFAMILY SSF110921 486 591 1.7E-37 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 SMART SM00917 464 593 7.8E-38 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 35 593 1.6E-263 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 Gene3D G3DSA:1.10.1220.20 427 480 3.5E-23 T 14-10-2018 A4R43_27355 4545da7feaa4e373b26fd6c0db4dcc3e 594 Pfam PF00682 HMGL-like 66 345 1.6E-76 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4R43_07605 d09e0750a562a872cc5d0bd7999ff861 289 Gene3D G3DSA:1.20.1260.130 2 265 6.4E-80 T 14-10-2018 A4R43_07605 d09e0750a562a872cc5d0bd7999ff861 289 SUPERFAMILY SSF47240 2 268 2.85E-88 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_07605 d09e0750a562a872cc5d0bd7999ff861 289 Pfam PF05067 Manganese containing catalase 2 256 5.9E-93 T 14-10-2018 IPR007760 Manganese catalase A4R43_04780 34265f06047cf49f49f473e1191bbdc5 306 Gene3D G3DSA:3.40.50.1100 52 145 4.6E-80 T 14-10-2018 A4R43_04780 34265f06047cf49f49f473e1191bbdc5 306 SUPERFAMILY SSF53686 9 301 1.83E-72 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_04780 34265f06047cf49f49f473e1191bbdc5 306 Gene3D G3DSA:3.40.50.1100 16 300 4.6E-80 T 14-10-2018 A4R43_04780 34265f06047cf49f49f473e1191bbdc5 306 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 298 3.4E-72 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 231 42.604 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 Gene3D G3DSA:1.10.287.610 97 152 2.1E-93 T 14-10-2018 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 Gene3D G3DSA:3.40.50.10490 10 214 2.1E-93 T 14-10-2018 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 Pfam PF00318 Ribosomal protein S2 9 224 7.0E-98 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.5E-39 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.5E-39 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.5E-39 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.5E-39 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.5E-39 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.5E-39 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 223 2.0E-109 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18395 6672ae401c3805c90d4753ade9c7aa7a 277 SUPERFAMILY SSF52313 6 225 3.01E-94 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A4R43_31030 ee625f8f324b5b4a077ead8983cd015a 93 Pfam PF11755 Protein of unknown function (DUF3311) 21 74 3.6E-14 T 14-10-2018 IPR021741 Protein of unknown function DUF3311 A4R43_40095 a176929391b14ff6123292e4b6bb32b8 147 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 37 145 4.5E-25 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_40095 a176929391b14ff6123292e4b6bb32b8 147 Pfam PF04075 F420H(2)-dependent quinone reductase 19 144 7.4E-31 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_40095 a176929391b14ff6123292e4b6bb32b8 147 Gene3D G3DSA:2.30.110.10 2 146 6.0E-44 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_23430 4e0446c5f8015e580f487fbcedb1f88a 196 SUPERFAMILY SSF46785 22 74 3.7E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_23430 4e0446c5f8015e580f487fbcedb1f88a 196 Gene3D G3DSA:1.10.10.10 16 90 9.9E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23430 4e0446c5f8015e580f487fbcedb1f88a 196 Gene3D G3DSA:3.30.460.10 97 173 3.8E-5 T 14-10-2018 A4R43_36160 afc81c2735e0901d47513b5f418697c3 975 Pfam PF12846 AAA-like domain 474 814 1.3E-22 T 14-10-2018 A4R43_36160 afc81c2735e0901d47513b5f418697c3 975 SUPERFAMILY SSF52540 449 811 7.97E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_36160 afc81c2735e0901d47513b5f418697c3 975 Gene3D G3DSA:3.40.50.300 631 817 2.2E-7 T 14-10-2018 A4R43_36160 afc81c2735e0901d47513b5f418697c3 975 Gene3D G3DSA:3.40.50.300 453 626 1.6E-5 T 14-10-2018 A4R43_08105 0be10e142fd7702f58001ea17973b3a8 281 Pfam PF13560 Helix-turn-helix domain 4 83 7.6E-15 T 14-10-2018 A4R43_08105 0be10e142fd7702f58001ea17973b3a8 281 Gene3D G3DSA:1.10.260.40 12 92 2.1E-7 T 14-10-2018 A4R43_08105 0be10e142fd7702f58001ea17973b3a8 281 SUPERFAMILY SSF47413 28 77 2.52E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_08105 0be10e142fd7702f58001ea17973b3a8 281 SMART SM00530 7 80 4.1E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_08105 0be10e142fd7702f58001ea17973b3a8 281 Gene3D G3DSA:3.30.450.180 106 281 9.4E-19 T 14-10-2018 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 SUPERFAMILY SSF54713 57 272 6.87E-40 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 273 3.8E-76 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 SUPERFAMILY SSF46934 3 56 4.9E-16 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 Hamap MF_00050 Elongation factor Ts [tsf]. 1 274 65.354 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 Gene3D G3DSA:3.30.479.20 159 272 7.4E-35 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 Gene3D G3DSA:1.10.8.10 1 56 2.8E-23 T 14-10-2018 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 Gene3D G3DSA:1.10.286.20 192 238 7.4E-35 T 14-10-2018 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 Pfam PF00889 Elongation factor TS 67 273 7.0E-63 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 A4R43_18390 c16cddbf7c5d30ea4423382168163ad5 274 Gene3D G3DSA:3.30.479.20 57 143 2.0E-19 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A4R43_32250 c078ffa02f0b87c4b480cb82294e43d6 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 6.4E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32250 c078ffa02f0b87c4b480cb82294e43d6 218 SUPERFAMILY SSF48498 81 206 3.5E-18 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_32250 c078ffa02f0b87c4b480cb82294e43d6 218 Gene3D G3DSA:1.10.357.10 1 211 2.2E-46 T 14-10-2018 A4R43_32250 c078ffa02f0b87c4b480cb82294e43d6 218 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_32250 c078ffa02f0b87c4b480cb82294e43d6 218 SUPERFAMILY SSF46689 3 83 2.34E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_32250 c078ffa02f0b87c4b480cb82294e43d6 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32250 c078ffa02f0b87c4b480cb82294e43d6 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36510 5ded3a8514c9d05d05281972c5a8e6c5 466 Gene3D G3DSA:3.60.110.10 202 422 6.6E-15 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_36510 5ded3a8514c9d05d05281972c5a8e6c5 466 Pfam PF00795 Carbon-nitrogen hydrolase 205 387 3.1E-9 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_36510 5ded3a8514c9d05d05281972c5a8e6c5 466 SUPERFAMILY SSF56317 204 432 8.89E-24 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_29585 5182315d9a9a858396c52a9364c290f6 310 Gene3D G3DSA:3.20.20.70 56 277 1.0E-39 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_29585 5182315d9a9a858396c52a9364c290f6 310 Pfam PF04055 Radical SAM superfamily 63 199 5.4E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_29585 5182315d9a9a858396c52a9364c290f6 310 SUPERFAMILY SSF102114 54 255 1.31E-41 T 14-10-2018 A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 Gene3D G3DSA:1.20.120.530 76 211 1.1E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 Pfam PF07729 FCD domain 81 202 3.4E-20 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 SUPERFAMILY SSF46785 5 75 1.7E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 SMART SM00895 81 203 2.3E-14 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 Gene3D G3DSA:1.10.10.10 2 71 2.8E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 6.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 6.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 63 1.3E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 SUPERFAMILY SSF48008 76 209 1.8E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_19790 e360c0fb8c54aaef4d8e1297699a6d46 212 SMART SM00345 13 71 2.3E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03845 8052f5ada8b917c816ec26b71aed6a22 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 8.5E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03845 8052f5ada8b917c816ec26b71aed6a22 214 Gene3D G3DSA:1.10.357.10 9 203 2.3E-39 T 14-10-2018 A4R43_03845 8052f5ada8b917c816ec26b71aed6a22 214 SUPERFAMILY SSF46689 9 95 3.59E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03845 8052f5ada8b917c816ec26b71aed6a22 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03845 8052f5ada8b917c816ec26b71aed6a22 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 Gene3D G3DSA:3.40.50.12740 2 213 3.4E-72 T 14-10-2018 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 SMART SM00448 2 114 3.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 SMART SM00421 150 207 2.5E-28 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 SUPERFAMILY SSF46894 143 213 5.1E-24 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 Pfam PF00072 Response regulator receiver domain 4 114 4.4E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 7.1E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30950 c645dc09f71e45d0983a1c58d16a7fb9 218 SUPERFAMILY SSF52172 2 134 8.4E-32 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 Pfam PF13404 AsnC-type helix-turn-helix domain 4 45 3.7E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 Gene3D G3DSA:3.30.70.920 58 140 3.8E-22 T 14-10-2018 A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 SUPERFAMILY SSF54909 65 152 6.3E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 Pfam PF01037 Lrp/AsnC ligand binding domain 70 143 5.6E-18 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 SUPERFAMILY SSF46785 4 63 3.24E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.3E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.3E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.3E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 SMART SM00344 4 113 1.7E-26 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_01580 c065621f22237b2b73a5f27a26616e3c 159 Gene3D G3DSA:1.10.10.10 1 57 4.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20630 dc12b695660e9dca288cf50f00bbe907 280 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 45 72 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A4R43_20630 dc12b695660e9dca288cf50f00bbe907 280 SMART SM00650 29 194 7.9E-43 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A4R43_20630 dc12b695660e9dca288cf50f00bbe907 280 Pfam PF00398 Ribosomal RNA adenine dimethylase 20 257 2.9E-32 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A4R43_20630 dc12b695660e9dca288cf50f00bbe907 280 Gene3D G3DSA:1.10.8.100 147 242 3.0E-39 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A4R43_20630 dc12b695660e9dca288cf50f00bbe907 280 SUPERFAMILY SSF53335 22 260 2.81E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_20630 dc12b695660e9dca288cf50f00bbe907 280 Gene3D G3DSA:3.40.50.150 22 194 3.0E-39 T 14-10-2018 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 SUPERFAMILY SSF48264 15 396 5.76E-90 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 Pfam PF00067 Cytochrome P450 202 362 2.6E-19 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 338 347 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00385 P450 superfamily signature 336 345 4.8E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00385 P450 superfamily signature 232 249 4.8E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00385 P450 superfamily signature 269 280 4.8E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00385 P450 superfamily signature 345 356 4.8E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 Gene3D G3DSA:1.10.630.10 8 396 4.6E-119 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 187 209 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 345 356 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 336 345 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 150 165 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 133 149 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 315 330 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 86 97 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 269 280 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40190 5429e6ac34cfbf7c9e57c88a24b3fc04 396 PRINTS PR00359 B-class P450 signature 287 314 3.3E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_08980 7d9684a7af08f7bf1c82be140adf27da 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 304 8.7E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_08980 7d9684a7af08f7bf1c82be140adf27da 307 SUPERFAMILY SSF161098 98 287 2.22E-28 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_08980 7d9684a7af08f7bf1c82be140adf27da 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 78 3.4E-9 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4R43_08980 7d9684a7af08f7bf1c82be140adf27da 307 Gene3D G3DSA:1.10.3720.10 92 305 5.4E-25 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 217 417 6.2E-47 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 SUPERFAMILY SSF48179 282 472 5.78E-34 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 Gene3D G3DSA:1.10.1040.10 282 474 9.9E-40 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 SUPERFAMILY SSF51735 23 280 2.87E-73 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 PRINTS PR00084 Mannitol dehydrogenase signature 218 231 1.1E-16 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 PRINTS PR00084 Mannitol dehydrogenase signature 248 263 1.1E-16 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 PRINTS PR00084 Mannitol dehydrogenase signature 31 41 1.1E-16 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 PRINTS PR00084 Mannitol dehydrogenase signature 178 191 1.1E-16 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 Gene3D G3DSA:3.40.50.720 10 280 5.3E-81 T 14-10-2018 A4R43_38245 2ccc3f80a5990ecfd672d7a45ac61f59 475 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 30 187 8.5E-30 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_36320 155773b3d129a00ebd45119acc6db06c 333 Pfam PF03576 Peptidase family S58 2 319 5.3E-73 T 14-10-2018 IPR005321 Peptidase S58, DmpA A4R43_36320 155773b3d129a00ebd45119acc6db06c 333 Gene3D G3DSA:3.60.70.12 1 330 2.6E-122 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_36320 155773b3d129a00ebd45119acc6db06c 333 SUPERFAMILY SSF56266 1 328 5.49E-73 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_06260 a70bb7cb54815f2b1296d40da459bc48 338 Gene3D G3DSA:3.30.420.40 1 296 3.2E-75 T 14-10-2018 A4R43_06260 a70bb7cb54815f2b1296d40da459bc48 338 SUPERFAMILY SSF53067 125 301 5.18E-35 T 14-10-2018 A4R43_06260 a70bb7cb54815f2b1296d40da459bc48 338 Gene3D G3DSA:3.30.420.150 104 289 3.2E-75 T 14-10-2018 A4R43_06260 a70bb7cb54815f2b1296d40da459bc48 338 Pfam PF02541 Ppx/GppA phosphatase family 28 300 7.6E-69 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4R43_06260 a70bb7cb54815f2b1296d40da459bc48 338 SUPERFAMILY SSF53067 1 121 1.63E-25 T 14-10-2018 A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 175 721 1.1E-179 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 Gene3D G3DSA:3.30.365.10 432 781 6.5E-138 T 14-10-2018 A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 SUPERFAMILY SSF56003 130 784 1.05E-206 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 Gene3D G3DSA:3.30.365.10 468 636 6.5E-138 T 14-10-2018 A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 Gene3D G3DSA:3.30.365.10 177 408 7.7E-76 T 14-10-2018 A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 SUPERFAMILY SSF54665 9 157 3.93E-42 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 Gene3D G3DSA:3.30.365.10 201 293 7.7E-76 T 14-10-2018 A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 138 3.0E-27 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 Gene3D G3DSA:3.90.1170.50 2 138 1.4E-44 T 14-10-2018 A4R43_19280 6008a7a548a6a784dcca695a099f8805 812 SMART SM01008 23 138 8.6E-49 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 SUPERFAMILY SSF53697 246 608 5.29E-90 T 14-10-2018 A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 Gene3D G3DSA:3.40.50.10490 251 607 9.6E-125 T 14-10-2018 A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 Gene3D G3DSA:3.40.50.10490 448 593 9.6E-125 T 14-10-2018 A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 608 36.091 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 Gene3D G3DSA:3.60.20.10 2 233 4.5E-70 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 Pfam PF13522 Glutamine amidotransferase domain 65 190 3.9E-19 T 14-10-2018 A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 SUPERFAMILY SSF56235 2 222 1.12E-64 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 Pfam PF01380 SIS domain 293 418 1.9E-25 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 Pfam PF01380 SIS domain 463 588 6.8E-18 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_09995 0955e1c26e0ef5669d64fe9b77f97fdd 608 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 608 1.5E-211 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4R43_19230 7f0cb9a8280a21edb351a7e8b14a3c7f 260 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_19230 7f0cb9a8280a21edb351a7e8b14a3c7f 260 Gene3D G3DSA:3.40.50.300 1 240 4.4E-53 T 14-10-2018 A4R43_19230 7f0cb9a8280a21edb351a7e8b14a3c7f 260 SUPERFAMILY SSF52540 3 224 2.05E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19230 7f0cb9a8280a21edb351a7e8b14a3c7f 260 Pfam PF00005 ABC transporter 20 174 1.5E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_19230 7f0cb9a8280a21edb351a7e8b14a3c7f 260 SMART SM00382 29 222 1.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 SUPERFAMILY SSF47781 478 566 2.11E-27 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Gene3D G3DSA:1.10.3500.10 117 506 8.9E-152 T 14-10-2018 IPR023323 Tex-like domain superfamily A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 SMART SM00732 333 432 7.8E-38 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 SMART SM00316 657 728 1.2E-24 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 SUPERFAMILY SSF53098 329 477 9.1E-52 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Pfam PF16921 Tex protein YqgF-like domain 334 459 2.1E-52 T 14-10-2018 IPR032639 Tex protein, YqgF-like domain A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 SUPERFAMILY SSF158832 8 328 2.09E-116 T 14-10-2018 A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 SUPERFAMILY SSF47781 568 639 7.34E-19 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Gene3D G3DSA:2.40.50.140 639 731 6.8E-26 T 14-10-2018 A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Pfam PF00575 S1 RNA binding domain 657 728 2.0E-17 T 14-10-2018 IPR003029 S1 domain GO:0003676 A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Pfam PF09371 Tex-like protein N-terminal domain 14 198 3.5E-67 T 14-10-2018 IPR018974 Tex-like protein, N-terminal A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 SUPERFAMILY SSF50249 646 731 8.95E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Gene3D G3DSA:1.10.10.650 7 114 1.7E-38 T 14-10-2018 IPR023319 Tex-like protein, HTH domain superfamily A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Gene3D G3DSA:3.30.420.140 332 459 8.9E-152 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Gene3D G3DSA:1.10.150.310 507 638 4.2E-48 T 14-10-2018 A4R43_27720 d7afaa089fc79b075c705c9f6b5a27df 789 Pfam PF12836 Helix-hairpin-helix motif 499 563 6.9E-29 T 14-10-2018 A4R43_28980 bc934649244143bde48d2efb1fad796c 654 SMART SM00220 6 226 5.0E-33 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_28980 bc934649244143bde48d2efb1fad796c 654 Pfam PF00069 Protein kinase domain 6 150 9.4E-27 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_28980 bc934649244143bde48d2efb1fad796c 654 SUPERFAMILY SSF56112 5 232 1.92E-52 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_28980 bc934649244143bde48d2efb1fad796c 654 Gene3D G3DSA:3.30.200.20 4 82 1.2E-9 T 14-10-2018 A4R43_28980 bc934649244143bde48d2efb1fad796c 654 Gene3D G3DSA:1.10.510.10 83 149 1.2E-16 T 14-10-2018 A4R43_28980 bc934649244143bde48d2efb1fad796c 654 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 118 130 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_28980 bc934649244143bde48d2efb1fad796c 654 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 12 35 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_28980 bc934649244143bde48d2efb1fad796c 654 Gene3D G3DSA:1.10.510.10 150 240 2.3E-12 T 14-10-2018 A4R43_02485 c63477e2f392dbbdeeb7cac039635d1d 356 Pfam PF13649 Methyltransferase domain 175 272 3.9E-11 T 14-10-2018 A4R43_02485 c63477e2f392dbbdeeb7cac039635d1d 356 Gene3D G3DSA:3.40.50.150 157 347 3.2E-23 T 14-10-2018 A4R43_02485 c63477e2f392dbbdeeb7cac039635d1d 356 SUPERFAMILY SSF53335 145 336 1.01E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_29425 ade0bdd4e2694db8a10a1aadb5bb47ec 216 SUPERFAMILY SSF52091 72 143 2.35E-7 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_29425 ade0bdd4e2694db8a10a1aadb5bb47ec 216 Pfam PF13466 STAS domain 71 142 4.2E-7 T 14-10-2018 IPR002645 STAS domain A4R43_29425 ade0bdd4e2694db8a10a1aadb5bb47ec 216 Gene3D G3DSA:3.30.750.24 56 151 8.2E-8 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_33820 aa343b2037a86506b22600f259595b9f 156 Gene3D G3DSA:1.10.455.10 2 156 2.1E-56 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A4R43_33820 aa343b2037a86506b22600f259595b9f 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.795 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A4R43_33820 aa343b2037a86506b22600f259595b9f 156 PIRSF PIRSF002122 5 156 2.7E-55 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A4R43_33820 aa343b2037a86506b22600f259595b9f 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33820 aa343b2037a86506b22600f259595b9f 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.2E-64 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A4R43_33820 aa343b2037a86506b22600f259595b9f 156 SUPERFAMILY SSF47973 1 149 7.59E-57 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A4R43_33820 aa343b2037a86506b22600f259595b9f 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.5E-59 T 14-10-2018 IPR023798 Ribosomal protein S7 domain A4R43_14585 9eb82581abb301165e958b16fd67a3a3 489 SUPERFAMILY SSF55961 344 486 6.34E-7 T 14-10-2018 A4R43_14585 9eb82581abb301165e958b16fd67a3a3 489 Pfam PF13460 NAD(P)H-binding 8 115 6.8E-19 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_14585 9eb82581abb301165e958b16fd67a3a3 489 Pfam PF11066 Protein of unknown function (DUF2867) 329 473 8.4E-40 T 14-10-2018 IPR021295 Protein of unknown function DUF2867 A4R43_14585 9eb82581abb301165e958b16fd67a3a3 489 Gene3D G3DSA:3.40.50.720 3 248 4.9E-43 T 14-10-2018 A4R43_14585 9eb82581abb301165e958b16fd67a3a3 489 SUPERFAMILY SSF51735 1 281 1.3E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Pfam PF01571 Aminomethyltransferase folate-binding domain 434 712 2.0E-76 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 SUPERFAMILY SSF103025 427 730 3.3E-92 T 14-10-2018 A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Gene3D G3DSA:3.30.70.1400 507 726 2.0E-113 T 14-10-2018 A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 SUPERFAMILY SSF51905 5 420 8.09E-62 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Gene3D G3DSA:3.30.1360.120 427 701 2.0E-113 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 SUPERFAMILY SSF54373 221 337 1.61E-31 T 14-10-2018 A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 SUPERFAMILY SSF101790 736 821 1.8E-23 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Pfam PF16350 FAD dependent oxidoreductase central domain 377 432 2.1E-15 T 14-10-2018 IPR032503 FAD dependent oxidoreductase, central domain A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Gene3D G3DSA:3.50.50.60 7 393 1.8E-145 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 719 809 3.9E-17 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Gene3D G3DSA:3.30.9.10 86 337 1.8E-145 T 14-10-2018 A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Pfam PF01266 FAD dependent oxidoreductase 6 374 6.5E-49 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_09625 a1a889adb13ae3c74e09da09e06a09be 822 Gene3D G3DSA:2.40.30.110 732 809 2.3E-34 T 14-10-2018 A4R43_15935 a08ba2661d6b2a79ffd2b1efc7aeb692 151 Gene3D G3DSA:2.30.110.10 14 135 1.5E-12 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_15935 a08ba2661d6b2a79ffd2b1efc7aeb692 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 23 101 3.5E-5 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_15935 a08ba2661d6b2a79ffd2b1efc7aeb692 151 SUPERFAMILY SSF50475 16 116 1.96E-15 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 SMART SM01260 34 414 1.4E-61 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 Gene3D G3DSA:1.50.10.20 26 416 2.7E-83 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01950 LanC-like protein superfamily signature 145 160 1.4E-20 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01950 LanC-like protein superfamily signature 37 55 1.4E-20 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01950 LanC-like protein superfamily signature 337 350 1.4E-20 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01950 LanC-like protein superfamily signature 287 307 1.4E-20 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01950 LanC-like protein superfamily signature 384 401 1.4E-20 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01950 LanC-like protein superfamily signature 212 228 1.4E-20 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 Pfam PF05147 Lanthionine synthetase C-like protein 34 400 8.4E-42 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 SUPERFAMILY SSF158745 33 401 2.35E-67 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 166 182 5.6E-78 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 38 53 5.6E-78 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 144 160 5.6E-78 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 209 233 5.6E-78 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 385 402 5.6E-78 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 83 99 5.6E-78 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 233 253 5.6E-78 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 336 356 5.6E-78 T 14-10-2018 A4R43_24690 64a8b521dbb8c76d399c97fc17095145 416 PRINTS PR01955 Frankia sp. LanC-like protein signature 287 310 5.6E-78 T 14-10-2018 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 247 1.2E-30 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 Gene3D G3DSA:3.10.150.10 1 125 2.9E-43 T 14-10-2018 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 122 2.6E-33 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 SUPERFAMILY SSF55979 133 249 8.97E-20 T 14-10-2018 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 Gene3D G3DSA:3.10.150.10 253 377 7.5E-44 T 14-10-2018 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 PIRSF PIRSF000804 1 376 4.1E-96 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 SUPERFAMILY SSF55979 1 122 2.28E-22 T 14-10-2018 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 359 6.6E-32 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 SMART SM00480 17 371 5.5E-120 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 Gene3D G3DSA:3.10.150.10 128 252 2.2E-31 T 14-10-2018 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 SUPERFAMILY SSF55979 250 375 1.84E-30 T 14-10-2018 A4R43_30425 a536d91e75a88a365181f4ce36573389 377 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 375 6.6E-97 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A4R43_03420 85597b431915f436be26a9495271a004 290 Gene3D G3DSA:1.10.10.10 1 91 1.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03420 85597b431915f436be26a9495271a004 290 Pfam PF03466 LysR substrate binding domain 89 287 1.9E-37 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_03420 85597b431915f436be26a9495271a004 290 SUPERFAMILY SSF53850 90 288 3.12E-37 T 14-10-2018 A4R43_03420 85597b431915f436be26a9495271a004 290 SUPERFAMILY SSF46785 1 84 1.82E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03420 85597b431915f436be26a9495271a004 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_03420 85597b431915f436be26a9495271a004 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_03420 85597b431915f436be26a9495271a004 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_03420 85597b431915f436be26a9495271a004 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_03420 85597b431915f436be26a9495271a004 290 Gene3D G3DSA:3.40.190.290 92 288 2.5E-43 T 14-10-2018 A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 SMART SM00065 121 275 6.6E-12 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 Pfam PF13185 GAF domain 121 266 2.5E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 Gene3D G3DSA:3.30.450.40 38 100 1.3E-7 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 Pfam PF07730 Histidine kinase 283 346 6.1E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 Gene3D G3DSA:3.30.565.10 347 474 3.8E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 SUPERFAMILY SSF55781 103 292 3.93E-21 T 14-10-2018 A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 SUPERFAMILY SSF55874 375 472 7.86E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 SUPERFAMILY SSF55781 45 117 4.76E-9 T 14-10-2018 A4R43_27565 f36497dc47f9061fa3e24f18b04d128f 479 Gene3D G3DSA:3.30.450.40 121 282 1.1E-29 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_33080 fd73087ac8c2b880d7dfc6c35cb28e79 138 Gene3D G3DSA:1.20.58.1610 12 138 1.3E-36 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33080 fd73087ac8c2b880d7dfc6c35cb28e79 138 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 18 138 17.266 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 A4R43_33080 fd73087ac8c2b880d7dfc6c35cb28e79 138 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 37 137 8.5E-31 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_03795 3f989affd859cba71ea3023e5b5605ce 153 SUPERFAMILY SSF47741 80 148 1.44E-27 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_03795 3f989affd859cba71ea3023e5b5605ce 153 Pfam PF01799 [2Fe-2S] binding domain 72 140 1.1E-27 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_03795 3f989affd859cba71ea3023e5b5605ce 153 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_03795 3f989affd859cba71ea3023e5b5605ce 153 Gene3D G3DSA:3.10.20.30 1 71 2.0E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_03795 3f989affd859cba71ea3023e5b5605ce 153 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 62 3.2E-9 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_03795 3f989affd859cba71ea3023e5b5605ce 153 Gene3D G3DSA:1.10.150.120 72 153 8.5E-29 T 14-10-2018 A4R43_03795 3f989affd859cba71ea3023e5b5605ce 153 SUPERFAMILY SSF54292 3 97 4.72E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 Gene3D G3DSA:3.40.50.12740 2 211 1.4E-71 T 14-10-2018 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 SUPERFAMILY SSF46894 147 210 8.5E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 SMART SM00421 150 207 1.5E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 4.0E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 SMART SM00448 2 115 4.2E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 7.5E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 7.5E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 7.5E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 SUPERFAMILY SSF52172 2 133 8.11E-35 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_08030 3d764296faa504c6a68f804771af16ee 212 Pfam PF00072 Response regulator receiver domain 4 116 2.7E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_08030 3d764296faa504c6a68f804771af16ee 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37925 fae137d80b956fb211137622f233bd7e 357 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 9 349 8.6E-86 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_37925 fae137d80b956fb211137622f233bd7e 357 SMART SM01329 8 352 2.4E-167 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_37925 fae137d80b956fb211137622f233bd7e 357 SUPERFAMILY SSF53659 4 356 2.69E-111 T 14-10-2018 A4R43_37925 fae137d80b956fb211137622f233bd7e 357 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 246 265 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4R43_37925 fae137d80b956fb211137622f233bd7e 357 Gene3D G3DSA:3.40.718.10 3 357 3.9E-130 T 14-10-2018 A4R43_37925 fae137d80b956fb211137622f233bd7e 357 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 4 356 4.6E-156 T 14-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 A4R43_19450 3f067141a3a48717b390df566c27a9b7 202 SMART SM00796 1 191 9.4E-87 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A4R43_19450 3f067141a3a48717b390df566c27a9b7 202 Gene3D G3DSA:2.40.100.10 74 202 2.4E-55 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_19450 3f067141a3a48717b390df566c27a9b7 202 Gene3D G3DSA:3.30.1360.40 1 73 1.2E-18 T 14-10-2018 A4R43_19450 3f067141a3a48717b390df566c27a9b7 202 SUPERFAMILY SSF160467 2 66 6.02E-10 T 14-10-2018 A4R43_19450 3f067141a3a48717b390df566c27a9b7 202 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 2 191 4.3E-67 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A4R43_19450 3f067141a3a48717b390df566c27a9b7 202 SUPERFAMILY SSF50891 81 201 1.06E-42 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 SMART SM00937 64 176 3.5E-51 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 Gene3D G3DSA:1.20.58.410 4 94 1.8E-9 T 14-10-2018 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 225 241 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 Gene3D G3DSA:3.30.70.1660 104 339 3.2E-92 T 14-10-2018 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 2 354 37.532 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 Pfam PF00472 RF-1 domain 209 318 6.8E-40 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 352 1.7E-146 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 SUPERFAMILY SSF75620 9 350 4.84E-127 T 14-10-2018 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 Gene3D G3DSA:3.30.160.20 208 294 3.2E-92 T 14-10-2018 A4R43_22425 251de79aea6fc76c6dbae7088da0adf5 355 Pfam PF03462 PCRF domain 11 201 8.3E-65 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 A4R43_07240 e5a044d78ebcf84f46ddd2a429ec5c51 122 Pfam PF03795 YCII-related domain 1 92 9.2E-9 T 14-10-2018 IPR005545 YCII-related A4R43_07240 e5a044d78ebcf84f46ddd2a429ec5c51 122 Gene3D G3DSA:3.30.70.1060 1 110 1.9E-21 T 14-10-2018 A4R43_07240 e5a044d78ebcf84f46ddd2a429ec5c51 122 SUPERFAMILY SSF54909 8 99 2.36E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_38410 777af355465c8caf8c369c2912b551f0 381 Pfam PF06441 Epoxide hydrolase N terminus 4 110 8.5E-35 T 14-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 A4R43_38410 777af355465c8caf8c369c2912b551f0 381 PRINTS PR00412 Epoxide hydrolase signature 127 142 1.0E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_38410 777af355465c8caf8c369c2912b551f0 381 PRINTS PR00412 Epoxide hydrolase signature 101 119 1.0E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_38410 777af355465c8caf8c369c2912b551f0 381 PRINTS PR00412 Epoxide hydrolase signature 172 185 1.0E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_38410 777af355465c8caf8c369c2912b551f0 381 PRINTS PR00412 Epoxide hydrolase signature 317 333 1.0E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_38410 777af355465c8caf8c369c2912b551f0 381 PRINTS PR00412 Epoxide hydrolase signature 349 371 1.0E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_38410 777af355465c8caf8c369c2912b551f0 381 SUPERFAMILY SSF53474 4 372 3.14E-94 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38410 777af355465c8caf8c369c2912b551f0 381 PIRSF PIRSF001112 1 377 3.4E-111 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_38410 777af355465c8caf8c369c2912b551f0 381 Gene3D G3DSA:3.40.50.1820 1 380 4.4E-134 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16335 bfac28b7a016e3a7eef2dd83ca2e2b81 253 Pfam PF01553 Acyltransferase 22 150 2.9E-25 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_16335 bfac28b7a016e3a7eef2dd83ca2e2b81 253 SMART SM00563 35 154 9.4E-37 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_16335 bfac28b7a016e3a7eef2dd83ca2e2b81 253 SUPERFAMILY SSF69593 3 222 2.35E-53 T 14-10-2018 A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 Gene3D G3DSA:1.10.3730.10 162 268 3.1E-40 T 14-10-2018 A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 219 241 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 263 4.8E-81 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 96 5.1E-20 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 SUPERFAMILY SSF51735 4 157 2.92E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 159 263 1.7E-37 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 Gene3D G3DSA:3.40.50.720 1 161 3.1E-43 T 14-10-2018 A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 263 26.912 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 SUPERFAMILY SSF48179 158 266 1.51E-36 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_32825 0d86cdf9b92f961b3d0018faec0aa2d1 268 PIRSF PIRSF000193 1 266 1.5E-71 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4R43_18800 4b077b5d949cedd1b1110c043ea6edfa 331 SUPERFAMILY SSF51679 8 326 5.36E-82 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_18800 4b077b5d949cedd1b1110c043ea6edfa 331 Gene3D G3DSA:3.20.20.30 4 330 2.1E-107 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_18800 4b077b5d949cedd1b1110c043ea6edfa 331 Pfam PF00296 Luciferase-like monooxygenase 24 305 4.1E-35 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_18800 4b077b5d949cedd1b1110c043ea6edfa 331 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 9 328 2.0E-133 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 A4R43_23700 4b416093c396aed4af562042829d4cee 399 Gene3D G3DSA:3.10.180.10 195 399 7.9E-79 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_23700 4b416093c396aed4af562042829d4cee 399 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 39 399 2.6E-129 T 14-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 A4R43_23700 4b416093c396aed4af562042829d4cee 399 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 41 141 3.4E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_23700 4b416093c396aed4af562042829d4cee 399 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 201 353 1.3E-12 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_23700 4b416093c396aed4af562042829d4cee 399 SUPERFAMILY SSF54593 31 386 1.27E-88 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_23700 4b416093c396aed4af562042829d4cee 399 Gene3D G3DSA:3.10.180.10 25 191 2.1E-48 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_23700 4b416093c396aed4af562042829d4cee 399 PIRSF PIRSF009283 27 399 1.4E-129 T 14-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 A4R43_03305 94d27f3539085404d920528a34232932 142 Pfam PF01638 HxlR-like helix-turn-helix 15 98 2.4E-19 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_03305 94d27f3539085404d920528a34232932 142 SUPERFAMILY SSF46785 4 135 2.41E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03305 94d27f3539085404d920528a34232932 142 Gene3D G3DSA:1.10.10.10 1 141 7.4E-43 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 Gene3D G3DSA:1.10.10.10 86 161 8.7E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 SUPERFAMILY SSF54427 168 276 6.1E-14 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 159 1.1E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 SUPERFAMILY SSF88946 3 90 3.1E-17 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 Pfam PF04542 Sigma-70 region 2 10 72 1.1E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 Gene3D G3DSA:1.10.1740.10 2 69 3.5E-10 T 14-10-2018 A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 SUPERFAMILY SSF88659 84 161 1.2E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 Pfam PF08281 Sigma-70, region 4 105 155 1.6E-6 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_19765 e49748895d8bf245d9366fa3311f3bfe 285 Gene3D G3DSA:3.10.450.50 165 277 5.3E-9 T 14-10-2018 A4R43_40960 b19647d5410d8898515ecd88efb9c781 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 11 136 2.1E-16 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_40960 b19647d5410d8898515ecd88efb9c781 143 Gene3D G3DSA:3.30.530.20 6 140 2.7E-17 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_40960 b19647d5410d8898515ecd88efb9c781 143 SUPERFAMILY SSF55961 11 137 8.84E-20 T 14-10-2018 A4R43_37345 fcef5a36cc707f61425e61551c8be88d 306 Pfam PF00296 Luciferase-like monooxygenase 18 227 1.9E-32 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_37345 fcef5a36cc707f61425e61551c8be88d 306 SUPERFAMILY SSF51679 8 296 1.24E-42 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_37345 fcef5a36cc707f61425e61551c8be88d 306 Gene3D G3DSA:3.20.20.30 6 298 3.0E-48 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_09955 91b0c3d282ad92c8ede725dd0aabd076 345 Gene3D G3DSA:3.60.110.10 1 345 1.2E-153 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_09955 91b0c3d282ad92c8ede725dd0aabd076 345 Pfam PF00795 Carbon-nitrogen hydrolase 15 267 4.9E-47 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_09955 91b0c3d282ad92c8ede725dd0aabd076 345 Hamap MF_01242 Aliphatic amidase [amiE]. 1 340 83.207 T 14-10-2018 IPR023719 Aliphatic amidase GO:0004040 KEGG: 00330+3.5.1.4|KEGG: 00360+3.5.1.4|KEGG: 00380+3.5.1.4|KEGG: 00627+3.5.1.4|KEGG: 00643+3.5.1.4|MetaCyc: PWY-3161|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 A4R43_09955 91b0c3d282ad92c8ede725dd0aabd076 345 SUPERFAMILY SSF56317 11 275 1.09E-55 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 Gene3D G3DSA:3.30.499.10 329 477 2.8E-50 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 7 464 8.7E-227 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 5 471 60.632 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 113 121 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 404 417 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 200 213 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 348 359 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 138 153 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 87 100 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 291 305 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 124 137 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 PRINTS PR00415 Aconitase family signature 214 227 6.3E-47 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 SUPERFAMILY SSF53732 4 471 1.31E-164 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 ProSitePatterns PS01244 Aconitase family signature 2. 404 417 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 Pfam PF00330 Aconitase family (aconitate hydratase) 11 462 5.5E-158 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 Gene3D G3DSA:3.30.499.20 8 291 3.4E-100 T 14-10-2018 A4R43_19595 087fa06565a3ca97408fa432c8cd1b73 479 ProSitePatterns PS00450 Aconitase family signature 1. 344 360 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4R43_06895 280017d777f192de4c8ed84fc9f4a12f 71 Pfam PF04149 Domain of unknown function (DUF397) 9 62 1.4E-20 T 14-10-2018 IPR007278 Domain of unknown function DUF397 A4R43_10630 a020a0302ab1853c28204ed1c8c2e78d 144 SUPERFAMILY SSF55781 3 139 2.21E-11 T 14-10-2018 A4R43_10630 a020a0302ab1853c28204ed1c8c2e78d 144 Gene3D G3DSA:3.30.450.40 2 142 2.8E-9 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_00055 3d5406c7a360715a6601f4324216a09e 247 SMART SM00346 3 92 1.3E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_00055 3d5406c7a360715a6601f4324216a09e 247 Gene3D G3DSA:3.30.450.40 79 247 3.3E-42 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_00055 3d5406c7a360715a6601f4324216a09e 247 Gene3D G3DSA:1.10.10.10 4 75 3.6E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00055 3d5406c7a360715a6601f4324216a09e 247 Pfam PF09339 IclR helix-turn-helix domain 6 56 2.1E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_00055 3d5406c7a360715a6601f4324216a09e 247 SUPERFAMILY SSF55781 67 244 7.85E-38 T 14-10-2018 A4R43_00055 3d5406c7a360715a6601f4324216a09e 247 SUPERFAMILY SSF46785 5 73 1.39E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00055 3d5406c7a360715a6601f4324216a09e 247 Pfam PF01614 Bacterial transcriptional regulator 125 240 1.7E-16 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_33065 a4e15196c30c81a4ca0ece4617b22500 368 Gene3D G3DSA:3.40.50.2000 2 192 2.8E-17 T 14-10-2018 A4R43_33065 a4e15196c30c81a4ca0ece4617b22500 368 Gene3D G3DSA:3.40.50.2000 193 353 5.7E-31 T 14-10-2018 A4R43_33065 a4e15196c30c81a4ca0ece4617b22500 368 Pfam PF00534 Glycosyl transferases group 1 198 348 5.7E-24 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_33065 a4e15196c30c81a4ca0ece4617b22500 368 SUPERFAMILY SSF53756 2 365 4.93E-59 T 14-10-2018 A4R43_33065 a4e15196c30c81a4ca0ece4617b22500 368 Pfam PF13579 Glycosyl transferase 4-like domain 15 175 1.8E-16 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Gene3D G3DSA:3.30.10.20 356 432 1.7E-10 T 14-10-2018 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Gene3D G3DSA:3.30.10.20 572 639 4.9E-15 T 14-10-2018 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Gene3D G3DSA:3.30.200.20 1 94 2.6E-35 T 14-10-2018 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 SUPERFAMILY SSF56112 8 275 6.07E-79 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Pfam PF00069 Protein kinase domain 11 265 4.8E-52 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Gene3D G3DSA:1.10.510.10 96 282 2.4E-57 T 14-10-2018 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Gene3D G3DSA:3.30.10.20 435 503 6.3E-11 T 14-10-2018 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Gene3D G3DSA:3.30.10.20 511 571 5.2E-14 T 14-10-2018 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Pfam PF03793 PASTA domain 438 503 2.7E-9 T 14-10-2018 IPR005543 PASTA domain A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Pfam PF03793 PASTA domain 514 568 1.9E-9 T 14-10-2018 IPR005543 PASTA domain A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Pfam PF03793 PASTA domain 360 432 6.7E-8 T 14-10-2018 IPR005543 PASTA domain A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 Pfam PF03793 PASTA domain 575 639 1.1E-14 T 14-10-2018 IPR005543 PASTA domain A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 SMART SM00740 356 433 1.7E-6 T 14-10-2018 IPR005543 PASTA domain A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 SMART SM00740 434 503 1.8E-9 T 14-10-2018 IPR005543 PASTA domain A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 SMART SM00740 570 639 6.2E-15 T 14-10-2018 IPR005543 PASTA domain A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 SMART SM00740 504 568 1.2E-9 T 14-10-2018 IPR005543 PASTA domain A4R43_29120 208d0bdcef264518e54f31dc5bc63875 657 SMART SM00220 11 274 5.2E-68 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_37295 7051edba8fdc88572517572e65841806 409 Pfam PF00067 Cytochrome P450 276 375 1.8E-19 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 SUPERFAMILY SSF48264 13 407 1.18E-84 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00385 P450 superfamily signature 354 365 4.0E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00385 P450 superfamily signature 242 259 4.0E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00385 P450 superfamily signature 277 288 4.0E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00385 P450 superfamily signature 345 354 4.0E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00359 B-class P450 signature 295 322 5.7E-32 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00359 B-class P450 signature 92 103 5.7E-32 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00359 B-class P450 signature 345 354 5.7E-32 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00359 B-class P450 signature 141 157 5.7E-32 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00359 B-class P450 signature 277 288 5.7E-32 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00359 B-class P450 signature 195 217 5.7E-32 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 PRINTS PR00359 B-class P450 signature 354 365 5.7E-32 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_37295 7051edba8fdc88572517572e65841806 409 Gene3D G3DSA:1.10.630.10 3 407 1.0E-125 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_21945 ea798002824d677482ae7a7f31e6d043 376 Pfam PF07730 Histidine kinase 186 252 3.4E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_21945 ea798002824d677482ae7a7f31e6d043 376 Pfam PF13796 Putative sensor 21 128 1.4E-25 T 14-10-2018 IPR025828 Putative sensor domain A4R43_21945 ea798002824d677482ae7a7f31e6d043 376 SUPERFAMILY SSF55874 265 373 6.45E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_21945 ea798002824d677482ae7a7f31e6d043 376 Gene3D G3DSA:3.30.565.10 256 374 1.9E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25685 74e27a489a9c7c6bfa3b36256117bd47 450 Gene3D G3DSA:3.40.710.10 5 319 2.2E-70 T 14-10-2018 A4R43_25685 74e27a489a9c7c6bfa3b36256117bd47 450 SUPERFAMILY SSF56601 11 315 3.42E-69 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_25685 74e27a489a9c7c6bfa3b36256117bd47 450 Pfam PF00144 Beta-lactamase 11 315 5.4E-55 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_39290 93bddd574da4a5d723d63f944bfe6c16 249 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_39290 93bddd574da4a5d723d63f944bfe6c16 249 SMART SM00382 41 227 1.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_39290 93bddd574da4a5d723d63f944bfe6c16 249 Pfam PF00005 ABC transporter 32 178 5.7E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_39290 93bddd574da4a5d723d63f944bfe6c16 249 Gene3D G3DSA:3.40.50.300 11 248 3.6E-66 T 14-10-2018 A4R43_39290 93bddd574da4a5d723d63f944bfe6c16 249 SUPERFAMILY SSF52540 13 231 7.87E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13505 41f4c2ef4f231ab3e6b8cdc306149e50 367 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 143 2.1E-17 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_13505 41f4c2ef4f231ab3e6b8cdc306149e50 367 Gene3D G3DSA:3.40.50.720 168 311 9.0E-79 T 14-10-2018 A4R43_13505 41f4c2ef4f231ab3e6b8cdc306149e50 367 SUPERFAMILY SSF51735 155 323 2.35E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13505 41f4c2ef4f231ab3e6b8cdc306149e50 367 SUPERFAMILY SSF50129 6 190 2.2E-31 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_13505 41f4c2ef4f231ab3e6b8cdc306149e50 367 Pfam PF00107 Zinc-binding dehydrogenase 193 321 3.1E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_13505 41f4c2ef4f231ab3e6b8cdc306149e50 367 Gene3D G3DSA:3.90.180.10 26 354 9.0E-79 T 14-10-2018 A4R43_10780 66225c79706cce474e1669bd8fef13fd 64 Pfam PF05639 Pup-like protein 7 64 4.6E-22 T 14-10-2018 IPR008515 Ubiquitin-like, Pup A4R43_10780 66225c79706cce474e1669bd8fef13fd 64 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 64 16.408 T 14-10-2018 IPR008515 Ubiquitin-like, Pup A4R43_10780 66225c79706cce474e1669bd8fef13fd 64 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 33 64 1.5E-20 T 14-10-2018 IPR008515 Ubiquitin-like, Pup A4R43_37155 c15b2a6443f28474c58b3aa62a3058db 429 SUPERFAMILY SSF103473 7 406 4.58E-37 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_37155 c15b2a6443f28474c58b3aa62a3058db 429 Pfam PF07690 Major Facilitator Superfamily 16 315 2.2E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_37155 c15b2a6443f28474c58b3aa62a3058db 429 Gene3D G3DSA:1.20.1250.20 6 409 1.1E-38 T 14-10-2018 A4R43_24145 aa679c89917b3687e231732862aaae53 272 SUPERFAMILY SSF51735 2 266 6.52E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_24145 aa679c89917b3687e231732862aaae53 272 Gene3D G3DSA:3.90.25.10 124 255 4.4E-60 T 14-10-2018 A4R43_24145 aa679c89917b3687e231732862aaae53 272 Pfam PF13460 NAD(P)H-binding 7 100 1.7E-15 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_24145 aa679c89917b3687e231732862aaae53 272 Gene3D G3DSA:3.40.50.720 4 253 4.4E-60 T 14-10-2018 A4R43_04820 d047bc69123a07f89207634d99975100 440 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 225 415 1.6E-71 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_04820 d047bc69123a07f89207634d99975100 440 Gene3D G3DSA:3.90.870.10 10 223 1.0E-92 T 14-10-2018 A4R43_04820 d047bc69123a07f89207634d99975100 440 SUPERFAMILY SSF55821 21 224 8.47E-84 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A4R43_04820 d047bc69123a07f89207634d99975100 440 Gene3D G3DSA:3.40.50.10990 224 396 5.1E-73 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_04820 d047bc69123a07f89207634d99975100 440 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 18 414 55.528 T 14-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_04820 d047bc69123a07f89207634d99975100 440 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 17 221 38.763 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04820 d047bc69123a07f89207634d99975100 440 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 24 216 5.5E-88 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04820 d047bc69123a07f89207634d99975100 440 Pfam PF00925 GTP cyclohydrolase II 225 392 3.0E-69 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_04820 d047bc69123a07f89207634d99975100 440 PIRSF PIRSF001259 18 425 9.3E-178 T 14-10-2018 A4R43_04820 d047bc69123a07f89207634d99975100 440 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 222 418 40.211 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_04820 d047bc69123a07f89207634d99975100 440 SUPERFAMILY SSF142695 223 395 1.96E-69 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_04820 d047bc69123a07f89207634d99975100 440 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 20 217 2.9E-75 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_02195 95a5766a54df75725a2782981d57e17b 600 Gene3D G3DSA:3.40.50.300 349 597 1.8E-71 T 14-10-2018 A4R43_02195 95a5766a54df75725a2782981d57e17b 600 Pfam PF00005 ABC transporter 367 524 7.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_02195 95a5766a54df75725a2782981d57e17b 600 Gene3D G3DSA:1.20.1560.10 3 336 3.6E-52 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_02195 95a5766a54df75725a2782981d57e17b 600 SUPERFAMILY SSF52540 343 586 2.25E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_02195 95a5766a54df75725a2782981d57e17b 600 SMART SM00382 376 570 2.4E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_02195 95a5766a54df75725a2782981d57e17b 600 SUPERFAMILY SSF90123 19 341 6.8E-54 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_02195 95a5766a54df75725a2782981d57e17b 600 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_02195 95a5766a54df75725a2782981d57e17b 600 Pfam PF00664 ABC transporter transmembrane region 35 305 1.4E-29 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_07900 12baa0b969efb6a1d86131bdac369ebc 364 SUPERFAMILY SSF53901 5 351 5.55E-50 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07900 12baa0b969efb6a1d86131bdac369ebc 364 Gene3D G3DSA:3.40.47.10 207 353 4.6E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07900 12baa0b969efb6a1d86131bdac369ebc 364 Gene3D G3DSA:3.40.47.10 4 202 6.1E-48 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07900 12baa0b969efb6a1d86131bdac369ebc 364 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 40 199 1.9E-13 T 14-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal A4R43_07900 12baa0b969efb6a1d86131bdac369ebc 364 PIRSF PIRSF000451 2 353 6.7E-100 T 14-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 A4R43_07900 12baa0b969efb6a1d86131bdac369ebc 364 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 234 349 5.2E-17 T 14-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 13 84 4.2E-19 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 SUPERFAMILY SSF47917 357 472 2.54E-47 T 14-10-2018 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 SMART SM00382 153 338 1.2E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 Gene3D G3DSA:3.40.50.300 87 356 2.4E-100 T 14-10-2018 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 141 354 3.7E-63 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 10 470 1.8E-239 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 Gene3D G3DSA:1.10.1140.10 357 475 3.7E-50 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 SUPERFAMILY SSF52540 88 360 2.5E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 SUPERFAMILY SSF50615 10 86 1.94E-22 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 Gene3D G3DSA:2.40.10.170 8 86 4.6E-26 T 14-10-2018 A4R43_22350 2b4296d0b846a2e0b4cd7687acd8e929 475 Hamap MF_01347 ATP synthase subunit beta [atpB]. 8 472 53.735 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A4R43_31845 f26b9d235c059241a20e9707b65bcba7 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 75 3.9E-15 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31845 f26b9d235c059241a20e9707b65bcba7 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 74 3.0E-21 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31845 f26b9d235c059241a20e9707b65bcba7 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 1.8E-25 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31845 f26b9d235c059241a20e9707b65bcba7 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 19.998 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31845 f26b9d235c059241a20e9707b65bcba7 79 Gene3D G3DSA:3.30.1280.10 2 79 3.8E-25 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_31845 f26b9d235c059241a20e9707b65bcba7 79 SUPERFAMILY SSF82697 3 76 4.19E-23 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4R43_13110 819aac99d21ea6dcd7027b88eb380683 440 Pfam PF00083 Sugar (and other) transporter 22 229 2.8E-24 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_13110 819aac99d21ea6dcd7027b88eb380683 440 Gene3D G3DSA:1.20.1250.20 17 434 4.5E-64 T 14-10-2018 A4R43_13110 819aac99d21ea6dcd7027b88eb380683 440 Pfam PF07690 Major Facilitator Superfamily 274 432 4.1E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_13110 819aac99d21ea6dcd7027b88eb380683 440 SUPERFAMILY SSF103473 17 427 2.62E-65 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 SMART SM00388 209 277 1.7E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 Gene3D G3DSA:3.30.565.10 289 424 8.9E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 SUPERFAMILY SSF158472 158 204 3.79E-5 T 14-10-2018 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 422 4.7E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 383 1.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 408 1.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 1.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 Pfam PF00672 HAMP domain 157 204 6.1E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 SUPERFAMILY SSF55874 266 423 4.32E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 SMART SM00387 318 424 3.0E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 SMART SM00304 155 208 9.7E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 210 277 1.9E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 Gene3D G3DSA:1.10.287.130 159 277 5.7E-25 T 14-10-2018 A4R43_00565 c7dd7e4a2a64d6a783c41be6cea6e202 424 SUPERFAMILY SSF47384 193 277 1.96E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_36935 e1561e521a9a30693da761857eeda340 346 Gene3D G3DSA:1.50.10.150 8 344 8.6E-14 T 14-10-2018 IPR038665 Voltage-dependent anion channel superfamily A4R43_36935 e1561e521a9a30693da761857eeda340 346 Pfam PF03595 Voltage-dependent anion channel 13 336 7.5E-59 T 14-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 A4R43_18895 57aeeefc1f01b51dde0c159e7dab2f84 196 SUPERFAMILY SSF55811 3 169 1.19E-43 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_18895 57aeeefc1f01b51dde0c159e7dab2f84 196 Pfam PF00293 NUDIX domain 30 160 3.1E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_18895 57aeeefc1f01b51dde0c159e7dab2f84 196 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 5 163 8.0E-45 T 14-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 A4R43_18895 57aeeefc1f01b51dde0c159e7dab2f84 196 PIRSF PIRSF018427 1 186 1.3E-53 T 14-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 A4R43_18895 57aeeefc1f01b51dde0c159e7dab2f84 196 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 3 175 31.949 T 14-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 A4R43_18895 57aeeefc1f01b51dde0c159e7dab2f84 196 Gene3D G3DSA:3.90.79.10 1 169 2.1E-50 T 14-10-2018 A4R43_32645 0808f3f34257cc43932dee3d5ab044c6 115 SUPERFAMILY SSF54909 3 111 3.75E-30 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_32645 0808f3f34257cc43932dee3d5ab044c6 115 Pfam PF03795 YCII-related domain 3 110 1.1E-20 T 14-10-2018 IPR005545 YCII-related A4R43_32645 0808f3f34257cc43932dee3d5ab044c6 115 Gene3D G3DSA:3.30.70.1060 1 114 5.2E-35 T 14-10-2018 A4R43_25495 c2be520d7212460695aa8c1cfd93499a 540 Gene3D G3DSA:3.40.462.40 86 491 1.7E-127 T 14-10-2018 A4R43_25495 c2be520d7212460695aa8c1cfd93499a 540 Gene3D G3DSA:1.10.45.10 500 539 2.3E-5 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4R43_25495 c2be520d7212460695aa8c1cfd93499a 540 Gene3D G3DSA:3.30.465.40 73 282 1.7E-127 T 14-10-2018 A4R43_25495 c2be520d7212460695aa8c1cfd93499a 540 SUPERFAMILY SSF56176 60 283 5.14E-47 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_25495 c2be520d7212460695aa8c1cfd93499a 540 SUPERFAMILY SSF55103 260 539 3.05E-32 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_25495 c2be520d7212460695aa8c1cfd93499a 540 Pfam PF01565 FAD binding domain 105 244 5.0E-35 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_25495 c2be520d7212460695aa8c1cfd93499a 540 Pfam PF02913 FAD linked oxidases, C-terminal domain 283 538 4.0E-33 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 SUPERFAMILY SSF48264 6 397 3.54E-91 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 Pfam PF00067 Cytochrome P450 204 365 1.9E-22 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 268 279 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 133 149 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 87 98 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 314 329 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 150 165 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 335 344 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 344 355 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 188 210 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 PRINTS PR00359 B-class P450 signature 286 313 1.5E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 Gene3D G3DSA:1.10.630.10 1 399 1.0E-122 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09330 bdefb2eae67db8380b5db56bb614f7c7 399 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 296 4.3E-53 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 SUPERFAMILY SSF55424 311 388 5.22E-16 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 SUPERFAMILY SSF51905 142 306 3.6E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 Gene3D G3DSA:3.30.390.30 319 391 2.7E-11 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 167 5.8E-13 T 14-10-2018 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 5.8E-13 T 14-10-2018 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 5.8E-13 T 14-10-2018 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 5.8E-13 T 14-10-2018 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 Gene3D G3DSA:3.50.50.60 112 234 1.4E-98 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 Pfam PF14759 Reductase C-terminal 319 386 1.9E-12 T 14-10-2018 IPR028202 Reductase, C-terminal A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 Gene3D G3DSA:3.50.50.60 4 296 1.4E-98 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 SUPERFAMILY SSF51905 4 186 1.81E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 5.3E-22 T 14-10-2018 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.3E-22 T 14-10-2018 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 5.3E-22 T 14-10-2018 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 5.3E-22 T 14-10-2018 A4R43_09670 2fb510d91af70cf733240d682e9becd1 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 5.3E-22 T 14-10-2018 A4R43_00020 7ab81c411dc19b831f7f9dddeb3dd0b6 216 Gene3D G3DSA:1.10.357.10 12 214 3.6E-60 T 14-10-2018 A4R43_00020 7ab81c411dc19b831f7f9dddeb3dd0b6 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00020 7ab81c411dc19b831f7f9dddeb3dd0b6 216 SUPERFAMILY SSF46689 7 88 1.39E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_28440 5818f711d4546a522e9e3c52e73ed8c5 310 SUPERFAMILY SSF52540 6 308 2.02E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28440 5818f711d4546a522e9e3c52e73ed8c5 310 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 9 309 3.4E-122 T 14-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4R43_28440 5818f711d4546a522e9e3c52e73ed8c5 310 PIRSF PIRSF000545 1 310 2.5E-139 T 14-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4R43_28440 5818f711d4546a522e9e3c52e73ed8c5 310 Hamap MF_00215 Pantothenate kinase [coaA]. 1 310 175.818 T 14-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4R43_28440 5818f711d4546a522e9e3c52e73ed8c5 310 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 90 227 2.7E-12 T 14-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 A4R43_28440 5818f711d4546a522e9e3c52e73ed8c5 310 Gene3D G3DSA:3.40.50.300 1 310 2.9E-94 T 14-10-2018 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 Gene3D G3DSA:3.30.410.40 149 452 9.7E-203 T 14-10-2018 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 Pfam PF00732 GMC oxidoreductase 5 299 2.0E-76 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 SUPERFAMILY SSF54373 293 455 5.98E-45 T 14-10-2018 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 257 271 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 Gene3D G3DSA:4.10.450.10 38 196 9.7E-203 T 14-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 Pfam PF05199 GMC oxidoreductase 370 507 1.1E-37 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 SUPERFAMILY SSF51905 2 516 8.16E-76 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 Gene3D G3DSA:3.50.50.60 4 511 9.7E-203 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 PIRSF PIRSF000137 322 517 4.9E-48 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 PIRSF PIRSF000137 1 320 6.7E-92 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_14000 1730f9e222f5cfa1521f3aea7f2d9f51 517 Gene3D G3DSA:1.10.1220.110 96 148 9.7E-203 T 14-10-2018 A4R43_05795 614aca9372938a9728b66b35bd236f10 571 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 211 337 5.2E-25 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_05795 614aca9372938a9728b66b35bd236f10 571 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 441 460 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4R43_05795 614aca9372938a9728b66b35bd236f10 571 Gene3D G3DSA:3.40.50.970 12 197 3.4E-60 T 14-10-2018 A4R43_05795 614aca9372938a9728b66b35bd236f10 571 SUPERFAMILY SSF52518 380 563 1.57E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_05795 614aca9372938a9728b66b35bd236f10 571 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 21 187 3.5E-49 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_05795 614aca9372938a9728b66b35bd236f10 571 Gene3D G3DSA:3.40.50.1220 202 367 2.0E-37 T 14-10-2018 A4R43_05795 614aca9372938a9728b66b35bd236f10 571 SUPERFAMILY SSF52467 171 367 1.26E-34 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_05795 614aca9372938a9728b66b35bd236f10 571 SUPERFAMILY SSF52518 20 193 4.71E-46 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_05795 614aca9372938a9728b66b35bd236f10 571 Gene3D G3DSA:3.40.50.970 368 566 2.5E-54 T 14-10-2018 A4R43_05795 614aca9372938a9728b66b35bd236f10 571 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 405 553 3.8E-29 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_09485 b1e2175b8655329a391ea6502f88bba7 233 Gene3D G3DSA:1.20.120.530 103 232 9.5E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_09485 b1e2175b8655329a391ea6502f88bba7 233 Pfam PF07729 FCD domain 110 229 5.4E-16 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_09485 b1e2175b8655329a391ea6502f88bba7 233 Gene3D G3DSA:1.10.10.10 20 95 2.1E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09485 b1e2175b8655329a391ea6502f88bba7 233 SUPERFAMILY SSF48008 105 229 5.23E-16 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_09485 b1e2175b8655329a391ea6502f88bba7 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 78 5.0E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_09485 b1e2175b8655329a391ea6502f88bba7 233 SMART SM00895 109 232 7.6E-12 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_09485 b1e2175b8655329a391ea6502f88bba7 233 SUPERFAMILY SSF46785 14 93 2.72E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 SMART SM00382 278 468 2.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 SMART SM00382 29 220 2.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 SUPERFAMILY SSF52540 4 232 7.01E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 Pfam PF00005 ABC transporter 21 171 2.8E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 Pfam PF00005 ABC transporter 269 419 2.2E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 SUPERFAMILY SSF52540 242 477 1.43E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 Gene3D G3DSA:3.40.50.300 2 239 1.8E-58 T 14-10-2018 A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 Gene3D G3DSA:3.40.50.300 240 485 3.6E-60 T 14-10-2018 A4R43_17205 edc34144dfe5d51fe348e85d3624a7d2 488 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_36340 99e8bd9fb61184beb53895500c287364 175 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 137 143 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4R43_36340 99e8bd9fb61184beb53895500c287364 175 Gene3D G3DSA:3.30.160.70 9 81 1.8E-7 T 14-10-2018 A4R43_36340 99e8bd9fb61184beb53895500c287364 175 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 87 167 3.6E-21 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4R43_36340 99e8bd9fb61184beb53895500c287364 175 SUPERFAMILY SSF46767 85 168 4.71E-21 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A4R43_36340 99e8bd9fb61184beb53895500c287364 175 SUPERFAMILY SSF53155 6 83 1.53E-8 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4R43_36340 99e8bd9fb61184beb53895500c287364 175 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 89 168 1.5E-22 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4R43_36340 99e8bd9fb61184beb53895500c287364 175 Gene3D G3DSA:1.10.10.10 86 171 4.1E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10295 eeaba218967aa732f91202da80beffa3 239 Gene3D G3DSA:3.40.50.150 5 235 1.2E-50 T 14-10-2018 A4R43_10295 eeaba218967aa732f91202da80beffa3 239 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 60 231 2.7E-33 T 14-10-2018 IPR008884 Macrocin-O-methyltransferase A4R43_10295 eeaba218967aa732f91202da80beffa3 239 SUPERFAMILY SSF53335 9 202 1.36E-11 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 Pfam PF17450 Alpha galactosidase A C-terminal beta sandwich domain 304 366 1.0E-5 T 14-10-2018 IPR035373 Alpha galactosidase A, C-terminal beta-sandwich domain A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 SMART SM00776 519 662 7.6E-68 T 14-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 Gene3D G3DSA:2.60.40.1180 304 389 3.6E-26 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 Pfam PF08305 NPCBM/NEW2 domain 522 660 1.1E-44 T 14-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 PRINTS PR00740 Glycosyl hydrolase family 27 signature 67 82 2.2E-63 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 PRINTS PR00740 Glycosyl hydrolase family 27 signature 257 278 2.2E-63 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 PRINTS PR00740 Glycosyl hydrolase family 27 signature 236 255 2.2E-63 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 PRINTS PR00740 Glycosyl hydrolase family 27 signature 171 189 2.2E-63 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 PRINTS PR00740 Glycosyl hydrolase family 27 signature 29 48 2.2E-63 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 PRINTS PR00740 Glycosyl hydrolase family 27 signature 108 129 2.2E-63 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 PRINTS PR00740 Glycosyl hydrolase family 27 signature 144 161 2.2E-63 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 Gene3D G3DSA:2.60.120.1060 516 661 4.1E-45 T 14-10-2018 IPR038637 NPCBM domain superfamily A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 419 492 1.5E-15 T 14-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 Gene3D G3DSA:3.20.20.70 28 303 1.1E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 SUPERFAMILY SSF51011 303 388 5.32E-23 T 14-10-2018 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 Pfam PF16499 Alpha galactosidase A 34 301 5.1E-80 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 SUPERFAMILY SSF51445 28 302 7.22E-103 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_15645 784e00034377ddc2fbf4d47cb94b1f7b 662 SUPERFAMILY SSF49785 521 662 4.08E-41 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_25280 11cd394cefc14516bfda76289a942270 92 PRINTS PR00107 Phosphocarrier protein signature 13 29 8.0E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_25280 11cd394cefc14516bfda76289a942270 92 PRINTS PR00107 Phosphocarrier protein signature 54 71 8.0E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_25280 11cd394cefc14516bfda76289a942270 92 PRINTS PR00107 Phosphocarrier protein signature 39 54 8.0E-11 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_25280 11cd394cefc14516bfda76289a942270 92 Gene3D G3DSA:3.30.1340.10 1 87 5.7E-21 T 14-10-2018 IPR035895 HPr-like superfamily A4R43_25280 11cd394cefc14516bfda76289a942270 92 SUPERFAMILY SSF55594 3 87 3.93E-20 T 14-10-2018 IPR035895 HPr-like superfamily A4R43_25280 11cd394cefc14516bfda76289a942270 92 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 82 4.7E-21 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_25280 11cd394cefc14516bfda76289a942270 92 Pfam PF00381 PTS HPr component phosphorylation site 4 83 1.1E-21 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like A4R43_15350 eca0600914e3684e742bb276c21ba592 321 Gene3D G3DSA:1.10.10.10 128 189 8.6E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15350 eca0600914e3684e742bb276c21ba592 321 Gene3D G3DSA:3.10.450.50 201 320 8.4E-18 T 14-10-2018 A4R43_15350 eca0600914e3684e742bb276c21ba592 321 SUPERFAMILY SSF88659 105 186 5.98E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_15350 eca0600914e3684e742bb276c21ba592 321 Gene3D G3DSA:1.10.1740.10 4 107 2.6E-25 T 14-10-2018 A4R43_15350 eca0600914e3684e742bb276c21ba592 321 Pfam PF04542 Sigma-70 region 2 30 92 4.1E-19 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_15350 eca0600914e3684e742bb276c21ba592 321 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 16 311 9.0E-95 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_15350 eca0600914e3684e742bb276c21ba592 321 SUPERFAMILY SSF88946 2 98 8.24E-27 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_15350 eca0600914e3684e742bb276c21ba592 321 Pfam PF08281 Sigma-70, region 4 134 184 3.3E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_15350 eca0600914e3684e742bb276c21ba592 321 Pfam PF12680 SnoaL-like domain 210 303 1.3E-9 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_15350 eca0600914e3684e742bb276c21ba592 321 SUPERFAMILY SSF54427 204 311 2.48E-16 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_15350 eca0600914e3684e742bb276c21ba592 321 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 185 3.8E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 SUPERFAMILY SSF52096 4 222 1.41E-42 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 Gene3D G3DSA:3.90.226.10 235 447 1.5E-52 T 14-10-2018 A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 147 164 2.3E-12 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 76 90 2.3E-12 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 110 128 2.3E-12 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 Gene3D G3DSA:3.90.226.10 3 222 2.1E-48 T 14-10-2018 A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 Pfam PF01039 Carboxyl transferase domain 45 181 1.2E-12 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 Pfam PF01039 Carboxyl transferase domain 284 413 7.6E-8 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_34230 64228e54ccd5f73589a4754594f3d8d5 447 SUPERFAMILY SSF52096 235 442 1.71E-43 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_24440 bbdf932ae7d5c0d0fee9c1a8663a1754 247 PIRSF PIRSF005902 1 244 5.3E-34 T 14-10-2018 IPR001130 TatD family GO:0016788 A4R43_24440 bbdf932ae7d5c0d0fee9c1a8663a1754 247 SUPERFAMILY SSF51556 2 240 5.96E-47 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_24440 bbdf932ae7d5c0d0fee9c1a8663a1754 247 Pfam PF01026 TatD related DNase 3 239 2.3E-35 T 14-10-2018 IPR001130 TatD family GO:0016788 A4R43_24440 bbdf932ae7d5c0d0fee9c1a8663a1754 247 Gene3D G3DSA:3.20.20.140 1 245 2.6E-57 T 14-10-2018 A4R43_09080 77b6f74e0622a20c650e1aa8ee0093c6 404 SUPERFAMILY SSF52266 200 403 2.44E-46 T 14-10-2018 A4R43_09080 77b6f74e0622a20c650e1aa8ee0093c6 404 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 206 392 9.3E-24 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_09080 77b6f74e0622a20c650e1aa8ee0093c6 404 Gene3D G3DSA:3.40.50.1110 179 404 2.9E-35 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_24940 cb6747c57416554ee58d0ea5452ea674 212 Gene3D G3DSA:3.40.630.30 21 196 3.1E-38 T 14-10-2018 A4R43_24940 cb6747c57416554ee58d0ea5452ea674 212 SUPERFAMILY SSF55729 23 191 6.83E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_24940 cb6747c57416554ee58d0ea5452ea674 212 Pfam PF13302 Acetyltransferase (GNAT) domain 24 167 1.8E-15 T 14-10-2018 IPR000182 GNAT domain A4R43_01630 807a88f81e8c7ab0c6d64f72dae257ec 154 Pfam PF01152 Bacterial-like globin 7 105 1.9E-15 T 14-10-2018 IPR001486 Truncated hemoglobin GO:0019825 A4R43_01630 807a88f81e8c7ab0c6d64f72dae257ec 154 Gene3D G3DSA:1.10.490.10 4 130 2.2E-29 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4R43_01630 807a88f81e8c7ab0c6d64f72dae257ec 154 SUPERFAMILY SSF46458 7 109 9.0E-25 T 14-10-2018 IPR009050 Globin-like superfamily A4R43_17810 95ea41ddac99959b92409cc759a9a2ac 341 SUPERFAMILY SSF160631 235 271 7.32E-8 T 14-10-2018 A4R43_17810 95ea41ddac99959b92409cc759a9a2ac 341 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 239 269 5.1E-6 T 14-10-2018 IPR018958 Knr4/Smi1-like domain A4R43_17810 95ea41ddac99959b92409cc759a9a2ac 341 SMART SM00860 239 334 5.1E-6 T 14-10-2018 IPR018958 Knr4/Smi1-like domain A4R43_17810 95ea41ddac99959b92409cc759a9a2ac 341 Gene3D G3DSA:3.40.1580.10 232 308 9.6E-6 T 14-10-2018 IPR037883 Knr4/Smi1-like domain superfamily A4R43_12675 4cba363e12a479e0a6687c0b7315f8ce 320 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 15 311 9.1E-101 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_12675 4cba363e12a479e0a6687c0b7315f8ce 320 Gene3D G3DSA:3.40.50.300 2 240 1.2E-64 T 14-10-2018 A4R43_12675 4cba363e12a479e0a6687c0b7315f8ce 320 SMART SM00382 32 239 4.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12675 4cba363e12a479e0a6687c0b7315f8ce 320 Pfam PF00005 ABC transporter 23 166 1.5E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_12675 4cba363e12a479e0a6687c0b7315f8ce 320 SUPERFAMILY SSF52540 7 228 2.17E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12675 4cba363e12a479e0a6687c0b7315f8ce 320 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_35085 1727d5c077e8e993fe977340e04c2364 284 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 270 1.8E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_33910 47a85273f75d2b7902f76c45a4b25313 132 Gene3D G3DSA:3.30.1370.30 4 74 1.7E-27 T 14-10-2018 A4R43_33910 47a85273f75d2b7902f76c45a4b25313 132 SUPERFAMILY SSF56047 3 132 2.75E-43 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33910 47a85273f75d2b7902f76c45a4b25313 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.099 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33910 47a85273f75d2b7902f76c45a4b25313 132 Gene3D G3DSA:3.30.1490.10 75 132 1.5E-23 T 14-10-2018 A4R43_33910 47a85273f75d2b7902f76c45a4b25313 132 Pfam PF00410 Ribosomal protein S8 5 132 6.3E-49 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33315 8e06165272e551e6844f64ef1d595f46 454 Pfam PF04932 O-Antigen ligase 233 357 2.2E-11 T 14-10-2018 IPR007016 O-antigen ligase-related A4R43_10375 e747c7dbae9e9feaf6a3944e2585fac8 200 Gene3D G3DSA:1.10.10.10 2 75 1.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10375 e747c7dbae9e9feaf6a3944e2585fac8 200 SMART SM00346 5 94 4.0E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_10375 e747c7dbae9e9feaf6a3944e2585fac8 200 Pfam PF09339 IclR helix-turn-helix domain 7 55 3.1E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_10375 e747c7dbae9e9feaf6a3944e2585fac8 200 SUPERFAMILY SSF46785 5 74 7.19E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_32725 0595dd18527aa037747923256dfb473b 266 Gene3D G3DSA:3.40.50.150 24 255 1.3E-8 T 14-10-2018 A4R43_32725 0595dd18527aa037747923256dfb473b 266 SUPERFAMILY SSF53335 18 167 1.47E-9 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_29650 405dfd98770d37e280183d40fd9e51ee 279 SUPERFAMILY SSF52540 2 204 9.11E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29650 405dfd98770d37e280183d40fd9e51ee 279 Gene3D G3DSA:3.40.50.300 2 235 8.0E-17 T 14-10-2018 A4R43_21055 e28d6c94b65ff6dcb463647a5f7e03fc 403 Pfam PF00990 Diguanylate cyclase, GGDEF domain 227 388 2.7E-44 T 14-10-2018 IPR000160 GGDEF domain A4R43_21055 e28d6c94b65ff6dcb463647a5f7e03fc 403 SMART SM00267 214 392 3.2E-57 T 14-10-2018 IPR000160 GGDEF domain A4R43_21055 e28d6c94b65ff6dcb463647a5f7e03fc 403 SUPERFAMILY SSF55073 231 393 6.04E-46 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_21055 e28d6c94b65ff6dcb463647a5f7e03fc 403 Gene3D G3DSA:3.30.70.270 215 394 3.8E-54 T 14-10-2018 A4R43_21055 e28d6c94b65ff6dcb463647a5f7e03fc 403 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 224 392 3.9E-45 T 14-10-2018 IPR000160 GGDEF domain A4R43_07720 00d3868b2f3d6ba59ccdae4f68147650 347 Gene3D G3DSA:3.30.530.90 133 346 1.7E-58 T 14-10-2018 A4R43_07720 00d3868b2f3d6ba59ccdae4f68147650 347 SUPERFAMILY SSF55961 107 341 3.85E-34 T 14-10-2018 A4R43_07720 00d3868b2f3d6ba59ccdae4f68147650 347 Pfam PF00355 Rieske [2Fe-2S] domain 8 91 5.2E-17 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4R43_07720 00d3868b2f3d6ba59ccdae4f68147650 347 Gene3D G3DSA:2.102.10.10 5 132 3.8E-34 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_07720 00d3868b2f3d6ba59ccdae4f68147650 347 SUPERFAMILY SSF50022 4 114 7.33E-32 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_08140 58653197946150896e2c2704545b05cc 823 Pfam PF13193 AMP-binding enzyme C-terminal domain 655 725 3.1E-15 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_08140 58653197946150896e2c2704545b05cc 823 Pfam PF00550 Phosphopantetheine attachment site 750 812 3.6E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_08140 58653197946150896e2c2704545b05cc 823 SMART SM00823 Phosphopantetheine attachment site 748 817 8.6E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_08140 58653197946150896e2c2704545b05cc 823 Gene3D G3DSA:3.30.300.30 641 734 2.3E-34 T 14-10-2018 A4R43_08140 58653197946150896e2c2704545b05cc 823 Pfam PF00501 AMP-binding enzyme 240 647 3.3E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_08140 58653197946150896e2c2704545b05cc 823 SUPERFAMILY SSF47336 740 813 2.09E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08140 58653197946150896e2c2704545b05cc 823 Gene3D G3DSA:3.30.559.30 3 227 2.5E-29 T 14-10-2018 A4R43_08140 58653197946150896e2c2704545b05cc 823 PRINTS PR00154 AMP-binding signature 380 391 9.9E-5 T 14-10-2018 IPR020459 AMP-binding A4R43_08140 58653197946150896e2c2704545b05cc 823 PRINTS PR00154 AMP-binding signature 392 400 9.9E-5 T 14-10-2018 IPR020459 AMP-binding A4R43_08140 58653197946150896e2c2704545b05cc 823 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 260 671 4.5E-128 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_08140 58653197946150896e2c2704545b05cc 823 ProSitePatterns PS00455 Putative AMP-binding domain signature. 385 396 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_08140 58653197946150896e2c2704545b05cc 823 SUPERFAMILY SSF52777 4 227 1.56E-20 T 14-10-2018 A4R43_08140 58653197946150896e2c2704545b05cc 823 Gene3D G3DSA:1.10.1200.10 735 817 8.2E-26 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_08140 58653197946150896e2c2704545b05cc 823 Gene3D G3DSA:3.40.50.12780 229 639 1.3E-127 T 14-10-2018 A4R43_08140 58653197946150896e2c2704545b05cc 823 SUPERFAMILY SSF56801 204 761 5.23E-152 T 14-10-2018 A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 SUPERFAMILY SSF54427 201 316 1.01E-16 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 Pfam PF12680 SnoaL-like domain 209 305 3.4E-8 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 16 321 3.1E-88 T 14-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 185 3.3E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 Gene3D G3DSA:1.10.10.10 127 191 2.3E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 SUPERFAMILY SSF88659 130 185 4.14E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 Pfam PF04542 Sigma-70 region 2 23 90 3.4E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 Pfam PF08281 Sigma-70, region 4 133 183 7.1E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 SUPERFAMILY SSF88946 7 95 2.88E-24 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 Gene3D G3DSA:3.10.450.50 198 319 2.1E-16 T 14-10-2018 A4R43_12895 360ecb8a5aa1ca5bbc90013bdf7cff36 326 Gene3D G3DSA:1.10.1740.10 6 102 8.9E-25 T 14-10-2018 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 4.2E-38 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 PRINTS PR00423 Cell division protein FtsZ signature 95 115 9.2E-51 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 PRINTS PR00423 Cell division protein FtsZ signature 209 230 9.2E-51 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 PRINTS PR00423 Cell division protein FtsZ signature 123 144 9.2E-51 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 PRINTS PR00423 Cell division protein FtsZ signature 186 208 9.2E-51 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 316 8.0E-126 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 Gene3D G3DSA:3.40.50.1440 1 217 4.8E-79 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 SMART SM00865 204 321 2.3E-55 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 SUPERFAMILY SSF52490 9 205 8.63E-65 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 Gene3D G3DSA:3.30.1330.20 218 325 1.7E-39 T 14-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 SMART SM00864 10 202 1.5E-106 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.0E-35 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 339 38.164 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A4R43_16510 93af21027592cbe6e992f9e6553b5c37 446 SUPERFAMILY SSF55307 201 315 1.76E-43 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 16 342 1.1E-66 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 375 651 1.4E-42 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 SUPERFAMILY SSF52279 375 654 1.96E-42 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 Gene3D G3DSA:3.40.50.1700 367 653 7.9E-56 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 SMART SM01217 689 758 6.4E-24 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 SUPERFAMILY SSF51445 5 373 3.05E-87 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 Gene3D G3DSA:2.60.40.10 657 771 7.0E-27 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 Gene3D G3DSA:3.20.20.300 2 356 7.7E-97 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 Pfam PF14310 Fibronectin type III-like domain 690 756 4.7E-17 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 PRINTS PR00133 Glycosyl hydrolase family 3 signature 110 129 9.5E-13 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 PRINTS PR00133 Glycosyl hydrolase family 3 signature 156 172 9.5E-13 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 PRINTS PR00133 Glycosyl hydrolase family 3 signature 191 207 9.5E-13 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_24295 43d7f9e9c6f0a40fa00674c732b7141d 774 PRINTS PR00133 Glycosyl hydrolase family 3 signature 262 280 9.5E-13 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 Gene3D G3DSA:3.30.540.10 4 152 2.2E-41 T 14-10-2018 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 92 105 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 72 88 4.8E-38 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 218 242 4.8E-38 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 141 164 4.8E-38 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 187 208 4.8E-38 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 50 70 4.8E-38 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 92 108 4.8E-38 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 Pfam PF00459 Inositol monophosphatase family 10 267 1.1E-57 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 SUPERFAMILY SSF56655 10 267 1.27E-68 T 14-10-2018 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 Gene3D G3DSA:3.40.190.80 153 272 8.8E-32 T 14-10-2018 A4R43_14075 0566e4c51cd807498c1d7b9bc75cd504 274 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 221 235 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4R43_10865 e599cbd2541b87176f8fb40dfd55c655 87 Gene3D G3DSA:1.10.287.1080 1 87 8.4E-22 T 14-10-2018 A4R43_10865 e599cbd2541b87176f8fb40dfd55c655 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 2.9E-21 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A4R43_10865 e599cbd2541b87176f8fb40dfd55c655 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 11 85 2.1E-5 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A4R43_10865 e599cbd2541b87176f8fb40dfd55c655 87 SUPERFAMILY SSF101386 2 87 2.18E-20 T 14-10-2018 A4R43_10865 e599cbd2541b87176f8fb40dfd55c655 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 17.403 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 SUPERFAMILY SSF51556 634 933 1.12E-47 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Pfam PF01979 Amidohydrolase family 632 967 1.7E-19 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Gene3D G3DSA:2.120.10.30 290 459 7.4E-38 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Gene3D G3DSA:3.20.20.140 641 929 1.1E-45 T 14-10-2018 A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 SUPERFAMILY SSF69304 314 570 3.53E-41 T 14-10-2018 A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 SUPERFAMILY SSF69304 45 273 2.22E-35 T 14-10-2018 A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Gene3D G3DSA:2.120.10.30 14 230 6.8E-51 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Pfam PF07676 WD40-like Beta Propeller Repeat 118 152 2.8E-8 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Pfam PF07676 WD40-like Beta Propeller Repeat 161 186 0.012 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Pfam PF07676 WD40-like Beta Propeller Repeat 394 412 0.0012 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Pfam PF07676 WD40-like Beta Propeller Repeat 492 510 9.8E-4 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Pfam PF07676 WD40-like Beta Propeller Repeat 74 108 1.4E-7 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Pfam PF07676 WD40-like Beta Propeller Repeat 344 378 7.4E-6 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Pfam PF07676 WD40-like Beta Propeller Repeat 315 327 0.093 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 Gene3D G3DSA:2.30.40.10 580 640 5.4E-8 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_36350 73b96e36f939f328fd41468ca0df4185 1017 SUPERFAMILY SSF51338 561 968 1.73E-12 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 Pfam PF03466 LysR substrate binding domain 88 288 2.4E-27 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.3E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 SUPERFAMILY SSF53850 90 292 1.21E-27 T 14-10-2018 A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 Gene3D G3DSA:1.10.10.10 1 90 7.9E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 Gene3D G3DSA:3.40.190.290 91 298 4.3E-30 T 14-10-2018 A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_37920 89fc1d316d0448055bc768f28bd30003 302 SUPERFAMILY SSF46785 1 85 3.46E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03540 75a70b3d69f434e32ca68c6d768bc2c3 293 Pfam PF00248 Aldo/keto reductase family 14 283 1.4E-57 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_03540 75a70b3d69f434e32ca68c6d768bc2c3 293 SUPERFAMILY SSF51430 1 284 2.75E-75 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_03540 75a70b3d69f434e32ca68c6d768bc2c3 293 Gene3D G3DSA:3.20.20.100 1 291 3.3E-79 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_26440 79c2228d835d5294e8026ffd0f3d253d 135 Pfam PF13380 CoA binding domain 13 126 6.1E-37 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_26440 79c2228d835d5294e8026ffd0f3d253d 135 Gene3D G3DSA:3.40.50.720 3 132 7.9E-40 T 14-10-2018 A4R43_26440 79c2228d835d5294e8026ffd0f3d253d 135 SUPERFAMILY SSF51735 7 127 5.45E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_26440 79c2228d835d5294e8026ffd0f3d253d 135 SMART SM00881 8 101 1.0E-22 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_09195 b2440ea16d242d62dbdc3ff8673488a4 119 Gene3D G3DSA:3.30.70.1060 1 119 1.4E-32 T 14-10-2018 A4R43_09195 b2440ea16d242d62dbdc3ff8673488a4 119 Pfam PF03795 YCII-related domain 1 114 2.4E-12 T 14-10-2018 IPR005545 YCII-related A4R43_09195 b2440ea16d242d62dbdc3ff8673488a4 119 SUPERFAMILY SSF54909 1 116 6.43E-23 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_00215 e17c04c9a853801f9df44a7defa45a8f 375 SUPERFAMILY SSF53756 2 364 1.32E-67 T 14-10-2018 A4R43_00215 e17c04c9a853801f9df44a7defa45a8f 375 Pfam PF06722 Protein of unknown function (DUF1205) 164 258 5.7E-14 T 14-10-2018 IPR010610 Domain of unknown function DUF1205 A4R43_00215 e17c04c9a853801f9df44a7defa45a8f 375 Gene3D G3DSA:3.40.50.2000 2 363 4.9E-104 T 14-10-2018 A4R43_00215 e17c04c9a853801f9df44a7defa45a8f 375 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 270 343 7.2E-6 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_00215 e17c04c9a853801f9df44a7defa45a8f 375 Gene3D G3DSA:3.40.50.2000 181 357 4.9E-104 T 14-10-2018 A4R43_18620 83ae0378c365118ace9b30b978513852 483 Gene3D G3DSA:1.10.10.2840 353 483 3.9E-26 T 14-10-2018 A4R43_18620 83ae0378c365118ace9b30b978513852 483 Pfam PF13556 PucR C-terminal helix-turn-helix domain 423 481 2.8E-21 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_18620 83ae0378c365118ace9b30b978513852 483 Pfam PF07905 Purine catabolism regulatory protein-like family 7 119 1.3E-24 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 SUPERFAMILY SSF56235 24 440 1.61E-151 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 Pfam PF01645 Conserved region in glutamate synthase 815 1180 4.7E-153 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 Gene3D G3DSA:2.160.20.60 1232 1500 1.9E-108 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 Pfam PF01493 GXGXG motif 1260 1443 1.5E-82 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 Pfam PF00310 Glutamine amidotransferases class-II 24 437 1.4E-180 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 Gene3D G3DSA:3.20.20.70 801 1231 1.9E-191 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 Gene3D G3DSA:3.60.20.10 24 444 4.8E-180 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 Pfam PF04898 Glutamate synthase central domain 463 750 5.6E-110 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 SUPERFAMILY SSF69336 1229 1488 4.97E-93 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 Gene3D G3DSA:3.20.20.70 445 800 3.4E-134 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_37890 13ad543d854e3caf5785edcebdaa99d0 1511 SUPERFAMILY SSF51395 455 1216 5.29E-261 T 14-10-2018 A4R43_28050 97619874e085331b3785c785cd7a04d1 399 Gene3D G3DSA:3.40.640.10 28 284 8.9E-115 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_28050 97619874e085331b3785c785cd7a04d1 399 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 8.9E-117 T 14-10-2018 IPR011340 Cysteine desulfurase-related A4R43_28050 97619874e085331b3785c785cd7a04d1 399 Pfam PF00266 Aminotransferase class-V 21 391 6.6E-35 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_28050 97619874e085331b3785c785cd7a04d1 399 Gene3D G3DSA:3.90.1150.10 18 395 8.9E-115 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_28050 97619874e085331b3785c785cd7a04d1 399 SUPERFAMILY SSF53383 3 398 3.16E-62 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_26850 9f5519d9c23aee9f1ceceb4e42c9c83b 327 Pfam PF09179 TilS substrate binding domain 252 317 2.4E-12 T 14-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4R43_26850 9f5519d9c23aee9f1ceceb4e42c9c83b 327 SUPERFAMILY SSF52402 31 237 1.57E-44 T 14-10-2018 A4R43_26850 9f5519d9c23aee9f1ceceb4e42c9c83b 327 SUPERFAMILY SSF82829 217 316 4.45E-16 T 14-10-2018 A4R43_26850 9f5519d9c23aee9f1ceceb4e42c9c83b 327 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 10 311 18.57 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4R43_26850 9f5519d9c23aee9f1ceceb4e42c9c83b 327 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 32 207 6.3E-35 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4R43_26850 9f5519d9c23aee9f1ceceb4e42c9c83b 327 Gene3D G3DSA:3.40.50.620 25 238 3.3E-58 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_26850 9f5519d9c23aee9f1ceceb4e42c9c83b 327 Pfam PF01171 PP-loop family 33 203 3.9E-30 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A4R43_06020 cfaebbd421c4f6322d311dc0e0191e7e 767 SMART SM01008 32 138 3.3E-45 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_06020 cfaebbd421c4f6322d311dc0e0191e7e 767 TIGRFAM TIGR03196 pucD: xanthine dehydrogenase D subunit 18 764 1.2E-250 T 14-10-2018 IPR017609 Xanthine dehydrogenase D subunit KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 A4R43_06020 cfaebbd421c4f6322d311dc0e0191e7e 767 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 33 137 1.1E-29 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_06020 cfaebbd421c4f6322d311dc0e0191e7e 767 SUPERFAMILY SSF54665 16 139 3.93E-40 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4R43_06020 cfaebbd421c4f6322d311dc0e0191e7e 767 Gene3D G3DSA:3.30.365.10 2 765 3.0E-202 T 14-10-2018 A4R43_06020 cfaebbd421c4f6322d311dc0e0191e7e 767 SUPERFAMILY SSF56003 130 765 7.07E-153 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_06020 cfaebbd421c4f6322d311dc0e0191e7e 767 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 160 709 1.2E-141 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 8.7E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 Pfam PF01037 Lrp/AsnC ligand binding domain 70 138 2.8E-17 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 Gene3D G3DSA:3.30.70.920 54 135 1.2E-22 T 14-10-2018 A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 7.8E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 7.8E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 7.8E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 SUPERFAMILY SSF46785 1 60 9.67E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 SMART SM00344 1 108 2.8E-38 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 SUPERFAMILY SSF54909 61 143 1.74E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_33000 4d70e7efac48860a1b1b4c74106373d3 157 Gene3D G3DSA:1.10.10.10 2 52 1.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18070 35d20414b30cbf86ccf42c9fe611237f 292 SUPERFAMILY SSF55048 113 161 2.88E-10 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_18070 35d20414b30cbf86ccf42c9fe611237f 292 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 285 1.1E-15 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_18070 35d20414b30cbf86ccf42c9fe611237f 292 Gene3D G3DSA:3.30.70.250 111 174 1.1E-74 T 14-10-2018 A4R43_18070 35d20414b30cbf86ccf42c9fe611237f 292 Pfam PF00698 Acyl transferase domain 20 267 4.2E-24 T 14-10-2018 IPR014043 Acyl transferase A4R43_18070 35d20414b30cbf86ccf42c9fe611237f 292 Gene3D G3DSA:3.40.366.10 1 264 1.1E-74 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4R43_18070 35d20414b30cbf86ccf42c9fe611237f 292 SUPERFAMILY SSF52151 1 274 1.96E-51 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_07595 c769b0cff3328d5310218b0a1bc0f6df 243 SMART SM00065 26 174 0.0013 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_07595 c769b0cff3328d5310218b0a1bc0f6df 243 PIRSF PIRSF036625 2 242 3.4E-39 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4R43_07595 c769b0cff3328d5310218b0a1bc0f6df 243 Gene3D G3DSA:3.30.450.40 10 172 2.1E-23 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_07595 c769b0cff3328d5310218b0a1bc0f6df 243 Pfam PF03861 ANTAR domain 183 230 1.1E-7 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_07595 c769b0cff3328d5310218b0a1bc0f6df 243 Pfam PF13185 GAF domain 26 159 6.2E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_07595 c769b0cff3328d5310218b0a1bc0f6df 243 SMART SM01012 176 231 6.2E-5 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_07595 c769b0cff3328d5310218b0a1bc0f6df 243 SUPERFAMILY SSF55781 26 164 2.18E-20 T 14-10-2018 A4R43_26550 1c60d0a2465f8e2ef1aa7df7741cd410 215 SUPERFAMILY SSF54001 45 208 1.23E-9 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_26550 1c60d0a2465f8e2ef1aa7df7741cd410 215 Pfam PF13529 Peptidase_C39 like family 51 190 8.6E-19 T 14-10-2018 IPR039564 Peptidase C39-like A4R43_26550 1c60d0a2465f8e2ef1aa7df7741cd410 215 Gene3D G3DSA:3.90.70.10 58 211 1.4E-6 T 14-10-2018 A4R43_31275 5785a809a9a6b9f071e4eb2fc702da49 232 SUPERFAMILY SSF53335 18 215 2.15E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_31275 5785a809a9a6b9f071e4eb2fc702da49 232 Gene3D G3DSA:3.40.50.150 43 229 1.3E-31 T 14-10-2018 A4R43_31275 5785a809a9a6b9f071e4eb2fc702da49 232 Pfam PF08241 Methyltransferase domain 55 146 1.5E-16 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_33790 d9e4d2f57d763a06b810f60d7167bcfd 287 SUPERFAMILY SSF51556 2 255 8.3E-50 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_33790 d9e4d2f57d763a06b810f60d7167bcfd 287 Pfam PF01026 TatD related DNase 4 230 6.6E-14 T 14-10-2018 IPR001130 TatD family GO:0016788 A4R43_33790 d9e4d2f57d763a06b810f60d7167bcfd 287 PIRSF PIRSF005295 2 259 8.6E-104 T 14-10-2018 IPR012022 Protein of unknown function UCP005295 A4R43_33790 d9e4d2f57d763a06b810f60d7167bcfd 287 Gene3D G3DSA:3.20.20.140 2 261 9.6E-48 T 14-10-2018 A4R43_29075 bc263102fec1a163ddba8a1b9ee62d08 124 Gene3D G3DSA:3.10.50.40 4 123 6.5E-41 T 14-10-2018 A4R43_29075 bc263102fec1a163ddba8a1b9ee62d08 124 SUPERFAMILY SSF54534 16 123 1.65E-39 T 14-10-2018 A4R43_29075 bc263102fec1a163ddba8a1b9ee62d08 124 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 30 121 1.2E-31 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A4R43_24010 c27a8950cdac0dc830be5325ec956632 591 SMART SM00267 397 563 1.2E-53 T 14-10-2018 IPR000160 GGDEF domain A4R43_24010 c27a8950cdac0dc830be5325ec956632 591 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 406 561 1.2E-42 T 14-10-2018 IPR000160 GGDEF domain A4R43_24010 c27a8950cdac0dc830be5325ec956632 591 Pfam PF00990 Diguanylate cyclase, GGDEF domain 408 559 8.4E-42 T 14-10-2018 IPR000160 GGDEF domain A4R43_24010 c27a8950cdac0dc830be5325ec956632 591 Gene3D G3DSA:3.30.70.270 394 563 2.6E-52 T 14-10-2018 A4R43_24010 c27a8950cdac0dc830be5325ec956632 591 SUPERFAMILY SSF48452 84 322 2.88E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_24010 c27a8950cdac0dc830be5325ec956632 591 SUPERFAMILY SSF55073 413 561 3.37E-42 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 Pfam PF13313 Domain of unknown function (DUF4082) 1194 1343 1.2E-55 T 14-10-2018 IPR025141 Domain of unknown function DUF4082 A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 Pfam PF13313 Domain of unknown function (DUF4082) 922 1073 1.8E-53 T 14-10-2018 IPR025141 Domain of unknown function DUF4082 A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 Pfam PF13313 Domain of unknown function (DUF4082) 651 801 3.2E-54 T 14-10-2018 IPR025141 Domain of unknown function DUF4082 A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 SUPERFAMILY SSF81296 564 635 1.68E-9 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 Gene3D G3DSA:2.60.40.10 820 910 9.5E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 Gene3D G3DSA:2.60.40.1220 1095 1184 7.9E-8 T 14-10-2018 A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 Gene3D G3DSA:2.60.40.10 551 647 1.0E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 Pfam PF13205 Bacterial Ig-like domain 812 909 2.7E-17 T 14-10-2018 IPR032812 SbsA, Ig-like domain A4R43_33360 e0ce42077545657dfd6750c8eecbe829 1351 Pfam PF13205 Bacterial Ig-like domain 1084 1184 9.1E-22 T 14-10-2018 IPR032812 SbsA, Ig-like domain A4R43_17990 2a5ae0b732915e177a24241fba0d9b4c 157 SUPERFAMILY SSF53254 1 133 1.67E-22 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_17990 2a5ae0b732915e177a24241fba0d9b4c 157 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 2 79 5.1E-9 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_17990 2a5ae0b732915e177a24241fba0d9b4c 157 Gene3D G3DSA:3.40.50.1240 1 153 1.0E-41 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.0E-41 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 SUPERFAMILY SSF56059 83 350 1.2E-68 T 14-10-2018 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 324 4.0E-77 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 SUPERFAMILY SSF51230 582 653 2.09E-20 T 14-10-2018 IPR011053 Single hybrid motif A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 Pfam PF02785 Biotin carboxylase C-terminal domain 338 444 6.0E-36 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 Gene3D G3DSA:2.40.50.100 579 654 2.2E-21 T 14-10-2018 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 Pfam PF00364 Biotin-requiring enzyme 588 652 2.6E-16 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 Gene3D G3DSA:3.30.470.130 1 450 1.6E-195 T 14-10-2018 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 SMART SM00878 338 444 2.1E-53 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 SUPERFAMILY SSF52440 2 113 1.65E-45 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 610 627 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 SUPERFAMILY SSF51246 333 448 4.97E-38 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4R43_22920 51f73e651e961e00083eda1db8d414ba 660 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 SUPERFAMILY SSF54980 432 546 5.28E-28 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 SUPERFAMILY SSF54980 335 421 1.01E-10 T 14-10-2018 IPR035647 EF-G domain III/V-like A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 SMART SM00838 429 517 0.0023 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 Gene3D G3DSA:3.30.70.870 340 623 2.3E-116 T 14-10-2018 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 PRINTS PR00315 GTP-binding elongation factor signature 69 77 4.6E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 PRINTS PR00315 GTP-binding elongation factor signature 93 103 4.6E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 PRINTS PR00315 GTP-binding elongation factor signature 25 38 4.6E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 PRINTS PR00315 GTP-binding elongation factor signature 145 154 4.6E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 PRINTS PR00315 GTP-binding elongation factor signature 109 120 4.6E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 24 167 2.2E-24 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 23 632 1.5E-273 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 Pfam PF03144 Elongation factor Tu domain 2 252 322 1.7E-11 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 SUPERFAMILY SSF50447 185 333 2.25E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 Pfam PF00009 Elongation factor Tu GTP binding domain 23 228 5.3E-53 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 SUPERFAMILY SSF52540 20 239 1.13E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 Gene3D G3DSA:3.30.70.240 423 515 2.3E-116 T 14-10-2018 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 Pfam PF00679 Elongation factor G C-terminus 430 514 1.7E-21 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 Gene3D G3DSA:2.40.30.10 232 332 8.2E-31 T 14-10-2018 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 Gene3D G3DSA:2.40.50.250 516 631 2.3E-116 T 14-10-2018 A4R43_23360 2f2661c601d77cd6e0a04400c801301f 641 Gene3D G3DSA:3.40.50.300 21 231 2.9E-57 T 14-10-2018 A4R43_01505 b5efc6e255837df06163cb941d2e22e1 413 SUPERFAMILY SSF56059 113 309 2.16E-21 T 14-10-2018 A4R43_01505 b5efc6e255837df06163cb941d2e22e1 413 Gene3D G3DSA:3.30.470.20 109 409 1.4E-24 T 14-10-2018 A4R43_10640 e142fab288fcce705473ac5acb4c30c3 290 SUPERFAMILY SSF53697 109 258 4.45E-22 T 14-10-2018 A4R43_10640 e142fab288fcce705473ac5acb4c30c3 290 Gene3D G3DSA:1.10.10.10 5 86 8.7E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10640 e142fab288fcce705473ac5acb4c30c3 290 SUPERFAMILY SSF46689 20 83 5.55E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_10640 e142fab288fcce705473ac5acb4c30c3 290 Gene3D G3DSA:3.40.50.10490 101 280 1.5E-33 T 14-10-2018 A4R43_10640 e142fab288fcce705473ac5acb4c30c3 290 Pfam PF01380 SIS domain 131 262 3.5E-13 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_10640 e142fab288fcce705473ac5acb4c30c3 290 Pfam PF01418 Helix-turn-helix domain, rpiR family 25 80 6.9E-7 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A4R43_32330 25debb1346fc0adde69a82d9113c8974 341 Pfam PF07732 Multicopper oxidase 72 181 1.1E-11 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 A4R43_32330 25debb1346fc0adde69a82d9113c8974 341 Gene3D G3DSA:2.60.40.420 37 184 4.0E-34 T 14-10-2018 IPR008972 Cupredoxin A4R43_32330 25debb1346fc0adde69a82d9113c8974 341 SUPERFAMILY SSF49503 72 188 1.3E-18 T 14-10-2018 IPR008972 Cupredoxin A4R43_32330 25debb1346fc0adde69a82d9113c8974 341 Gene3D G3DSA:2.60.40.420 187 340 4.0E-39 T 14-10-2018 IPR008972 Cupredoxin A4R43_32330 25debb1346fc0adde69a82d9113c8974 341 Pfam PF07731 Multicopper oxidase 199 305 1.1E-16 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 A4R43_32330 25debb1346fc0adde69a82d9113c8974 341 ProSitePatterns PS00080 Multicopper oxidases signature 2. 286 297 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 A4R43_32330 25debb1346fc0adde69a82d9113c8974 341 SUPERFAMILY SSF49503 192 306 2.45E-22 T 14-10-2018 IPR008972 Cupredoxin A4R43_13995 46769886e85babbbff420d126f97ed2b 503 PIRSF PIRSF006060 4 503 1.7E-63 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_13995 46769886e85babbbff420d126f97ed2b 503 Pfam PF13520 Amino acid permease 24 458 1.0E-41 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_13995 46769886e85babbbff420d126f97ed2b 503 Gene3D G3DSA:1.20.1740.10 15 451 5.3E-47 T 14-10-2018 A4R43_01935 f4131808c313bbf7e2eb64b65df64e43 64 Gene3D G3DSA:2.60.40.1890 5 47 2.3E-5 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily A4R43_01935 f4131808c313bbf7e2eb64b65df64e43 64 SUPERFAMILY SSF110087 7 47 8.89E-7 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 SUPERFAMILY SSF51735 4 230 8.83E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 Gene3D G3DSA:3.40.50.720 5 242 6.2E-68 T 14-10-2018 A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.9E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.9E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.9E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 189 0.0015 T 14-10-2018 A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41745 465e5b933451084fdcb4acb5772f1fec 244 Pfam PF00106 short chain dehydrogenase 7 198 1.5E-52 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 SUPERFAMILY SSF64153 4 237 1.22E-47 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 216 478 18.738 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 230 458 8.1E-42 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 Pfam PF01256 Carbohydrate kinase 241 457 2.6E-51 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 204 19.435 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 SUPERFAMILY SSF53613 217 473 2.46E-53 T 14-10-2018 IPR029056 Ribokinase-like A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 Gene3D G3DSA:3.40.50.10260 4 209 8.8E-47 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 PIRSF PIRSF017184 2 475 9.5E-92 T 14-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 20 203 2.1E-26 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 416 426 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 Gene3D G3DSA:3.40.1190.20 215 480 4.9E-70 T 14-10-2018 IPR029056 Ribokinase-like A4R43_34160 56ea4dba58117d2578aa545463113c0a 482 Pfam PF03853 YjeF-related protein N-terminus 25 184 3.4E-37 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4R43_10315 5dadddf131ae83024dde5bb8e70fe452 248 SUPERFAMILY SSF55781 74 246 2.16E-48 T 14-10-2018 A4R43_10315 5dadddf131ae83024dde5bb8e70fe452 248 SUPERFAMILY SSF46785 8 77 7.48E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_10315 5dadddf131ae83024dde5bb8e70fe452 248 Pfam PF01614 Bacterial transcriptional regulator 124 242 2.4E-29 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_10315 5dadddf131ae83024dde5bb8e70fe452 248 Pfam PF09339 IclR helix-turn-helix domain 9 57 6.6E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_10315 5dadddf131ae83024dde5bb8e70fe452 248 SMART SM00346 7 93 1.4E-19 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_10315 5dadddf131ae83024dde5bb8e70fe452 248 Gene3D G3DSA:3.30.450.40 77 248 3.0E-55 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_10315 5dadddf131ae83024dde5bb8e70fe452 248 Gene3D G3DSA:1.10.10.10 6 76 1.0E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23175 737bbdcd61275b2914afa42f6d6a14bc 542 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 541 3.8E-240 T 14-10-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 A4R43_23175 737bbdcd61275b2914afa42f6d6a14bc 542 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_23175 737bbdcd61275b2914afa42f6d6a14bc 542 Pfam PF00171 Aldehyde dehydrogenase family 56 524 3.2E-99 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_23175 737bbdcd61275b2914afa42f6d6a14bc 542 Gene3D G3DSA:3.40.605.10 14 527 1.5E-197 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_23175 737bbdcd61275b2914afa42f6d6a14bc 542 Gene3D G3DSA:3.40.309.10 297 495 1.5E-197 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_23175 737bbdcd61275b2914afa42f6d6a14bc 542 SUPERFAMILY SSF53720 7 527 6.94E-121 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 SMART SM00091 213 279 0.0011 T 14-10-2018 IPR000014 PAS domain A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 Gene3D G3DSA:3.30.450.20 201 312 2.0E-21 T 14-10-2018 A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 SUPERFAMILY SSF55874 412 527 6.55E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 2.1E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 2.1E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 Gene3D G3DSA:3.30.450.20 34 171 2.8E-43 T 14-10-2018 A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 SUPERFAMILY SSF55890 324 389 7.59E-5 T 14-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 SUPERFAMILY SSF55785 206 300 1.9E-7 T 14-10-2018 IPR035965 PAS domain superfamily A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 SUPERFAMILY SSF103190 40 169 2.67E-35 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 Pfam PF17203 Single cache domain 3 37 171 6.9E-31 T 14-10-2018 IPR033463 Single cache domain 3 A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 418 528 4.8E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 SMART SM00387 417 530 4.0E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_14465 f34fcc510f94414827bcb5d9a414378e 532 Gene3D G3DSA:3.30.565.10 380 531 1.8E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 Gene3D G3DSA:3.40.430.10 1 155 1.6E-51 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 Pfam PF00186 Dihydrofolate reductase 2 130 6.1E-47 T 14-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 14-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 SUPERFAMILY SSF53597 2 151 6.45E-49 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 PIRSF PIRSF000194 1 154 1.1E-48 T 14-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 PRINTS PR00070 Dihydrofolate reductase signature 27 35 3.3E-16 T 14-10-2018 A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 PRINTS PR00070 Dihydrofolate reductase signature 40 51 3.3E-16 T 14-10-2018 A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 PRINTS PR00070 Dihydrofolate reductase signature 13 23 3.3E-16 T 14-10-2018 A4R43_12930 3a09eef13030e9e8ca3f5505295477c5 159 PRINTS PR00070 Dihydrofolate reductase signature 89 103 3.3E-16 T 14-10-2018 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 Pfam PF00072 Response regulator receiver domain 4 118 9.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 7.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 8.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 8.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 8.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 Gene3D G3DSA:3.40.50.12740 2 213 4.8E-64 T 14-10-2018 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 SUPERFAMILY SSF46894 139 213 9.18E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 SMART SM00421 150 207 2.7E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 SUPERFAMILY SSF52172 2 127 2.13E-30 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_39525 dab874ed789bb004bd07cb05eb16586f 217 SMART SM00448 2 117 4.7E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_09870 a27ee1d0fd3ba9f19262877e3d6d915e 127 SUPERFAMILY SSF55331 2 125 3.67E-33 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily A4R43_09870 a27ee1d0fd3ba9f19262877e3d6d915e 127 Pfam PF14552 Tautomerase enzyme 37 119 5.6E-28 T 14-10-2018 IPR037479 Tautomerase, MSAD family A4R43_09870 a27ee1d0fd3ba9f19262877e3d6d915e 127 Gene3D G3DSA:3.30.429.10 2 127 6.9E-43 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily A4R43_33190 bb48ac3eec4e1912b241361cbb6e8d9f 382 SUPERFAMILY SSF140459 110 178 7.06E-5 T 14-10-2018 A4R43_30845 89a4c3681d0d7fc1979b2705fb860aff 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 134 181 3.4E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_30845 89a4c3681d0d7fc1979b2705fb860aff 216 Gene3D G3DSA:1.10.150.240 14 83 1.5E-45 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_30845 89a4c3681d0d7fc1979b2705fb860aff 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 182 1.8E-23 T 14-10-2018 A4R43_30845 89a4c3681d0d7fc1979b2705fb860aff 216 SUPERFAMILY SSF56784 1 211 2.99E-48 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_30845 89a4c3681d0d7fc1979b2705fb860aff 216 Gene3D G3DSA:3.40.50.1000 4 190 1.5E-45 T 14-10-2018 IPR023214 HAD superfamily A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 SUPERFAMILY SSF81653 138 235 4.05E-22 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 544 2.3E-41 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 185 199 1.6E-22 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 455 466 1.6E-22 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 531 550 1.6E-22 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 478 488 1.6E-22 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 1.6E-22 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 1.6E-22 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 Gene3D G3DSA:2.70.150.20 123 239 1.8E-34 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 85 634 5.0E-170 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 SUPERFAMILY SSF81665 87 329 2.48E-9 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00941 Cadmium-transporting ATPase signature 220 234 9.9E-8 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00941 Cadmium-transporting ATPase signature 201 217 9.9E-8 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 PRINTS PR00941 Cadmium-transporting ATPase signature 120 140 9.9E-8 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 Gene3D G3DSA:3.40.50.1000 316 583 5.4E-79 T 14-10-2018 IPR023214 HAD superfamily A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 Gene3D G3DSA:3.40.1110.10 346 462 5.4E-79 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 SUPERFAMILY SSF56784 334 631 3.71E-48 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 Pfam PF00122 E1-E2 ATPase 136 314 7.4E-42 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 85 636 5.0E-147 T 14-10-2018 A4R43_07810 6dd7564d492e2125ada34f49efdf1b4b 645 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 109 594 2.4E-65 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4R43_27390 355aef824c1d403edebe97923cf35442 380 Gene3D G3DSA:3.40.50.300 14 353 1.8E-99 T 14-10-2018 A4R43_27390 355aef824c1d403edebe97923cf35442 380 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_27390 355aef824c1d403edebe97923cf35442 380 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 338 3.3E-24 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_27390 355aef824c1d403edebe97923cf35442 380 SUPERFAMILY SSF52540 19 268 8.68E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27390 355aef824c1d403edebe97923cf35442 380 SMART SM00382 53 246 1.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_27390 355aef824c1d403edebe97923cf35442 380 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 314 2.1E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_27390 355aef824c1d403edebe97923cf35442 380 Pfam PF00005 ABC transporter 45 196 3.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14970 a4a2fd6194f9024b53691b5448b701cc 862 Pfam PF00589 Phage integrase family 502 681 4.8E-16 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_14970 a4a2fd6194f9024b53691b5448b701cc 862 SUPERFAMILY SSF56349 440 687 1.06E-23 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_14970 a4a2fd6194f9024b53691b5448b701cc 862 Gene3D G3DSA:1.10.443.10 492 694 2.4E-22 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_29890 a4a2fd6194f9024b53691b5448b701cc 862 Pfam PF00589 Phage integrase family 502 681 4.8E-16 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_29890 a4a2fd6194f9024b53691b5448b701cc 862 SUPERFAMILY SSF56349 440 687 1.06E-23 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_29890 a4a2fd6194f9024b53691b5448b701cc 862 Gene3D G3DSA:1.10.443.10 492 694 2.4E-22 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_30275 a4a2fd6194f9024b53691b5448b701cc 862 Pfam PF00589 Phage integrase family 502 681 4.8E-16 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_30275 a4a2fd6194f9024b53691b5448b701cc 862 SUPERFAMILY SSF56349 440 687 1.06E-23 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_30275 a4a2fd6194f9024b53691b5448b701cc 862 Gene3D G3DSA:1.10.443.10 492 694 2.4E-22 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_11450 7f57eeb4e0ededc823e9252a2b5fb4bc 127 SUPERFAMILY SSF50475 6 125 6.83E-27 T 14-10-2018 A4R43_11450 7f57eeb4e0ededc823e9252a2b5fb4bc 127 Gene3D G3DSA:2.30.110.10 2 127 7.4E-38 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_11450 7f57eeb4e0ededc823e9252a2b5fb4bc 127 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 8 123 3.6E-25 T 14-10-2018 IPR019920 F420-binding domain, putative A4R43_11450 7f57eeb4e0ededc823e9252a2b5fb4bc 127 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 90 7.2E-10 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_04975 1adb9568015d865856adc36eb19fc626 323 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 31 313 18.901 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A4R43_04975 1adb9568015d865856adc36eb19fc626 323 Gene3D G3DSA:1.10.357.140 43 195 7.4E-18 T 14-10-2018 A4R43_04975 1adb9568015d865856adc36eb19fc626 323 Pfam PF01040 UbiA prenyltransferase family 47 295 3.3E-65 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A4R43_04975 1adb9568015d865856adc36eb19fc626 323 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 34 312 3.7E-99 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 Gene3D G3DSA:3.40.50.720 1 163 3.0E-55 T 14-10-2018 A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 PIRSF PIRSF000103 1 293 2.8E-79 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 4.7E-49 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 SUPERFAMILY SSF51735 4 164 9.68E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 Gene3D G3DSA:1.10.1040.10 164 293 1.5E-37 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 SUPERFAMILY SSF48179 164 291 2.04E-35 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 5 291 8.6E-111 T 14-10-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 A4R43_05770 eea35e845486d4c09ac73a34f48a1ca7 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 285 1.6E-35 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A4R43_20245 2090d33f06ca9e480f56632f7c3a3e37 317 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 306 1.3E-85 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A4R43_20245 2090d33f06ca9e480f56632f7c3a3e37 317 SUPERFAMILY SSF53590 4 313 8.5E-87 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like A4R43_20245 2090d33f06ca9e480f56632f7c3a3e37 317 Gene3D G3DSA:3.90.245.10 1 316 6.1E-98 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like A4R43_02655 8908d4ef2ec03a471e18e3b94e9dc2a6 325 SMART SM01092 224 322 5.7E-24 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_02655 8908d4ef2ec03a471e18e3b94e9dc2a6 325 SUPERFAMILY SSF55447 223 321 6.41E-27 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily A4R43_02655 8908d4ef2ec03a471e18e3b94e9dc2a6 325 SUPERFAMILY SSF56176 1 217 6.54E-58 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_02655 8908d4ef2ec03a471e18e3b94e9dc2a6 325 Gene3D G3DSA:3.30.390.50 221 323 1.4E-24 T 14-10-2018 A4R43_02655 8908d4ef2ec03a471e18e3b94e9dc2a6 325 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 225 321 9.0E-20 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_02655 8908d4ef2ec03a471e18e3b94e9dc2a6 325 Gene3D G3DSA:3.30.465.10 1 218 4.6E-79 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_02655 8908d4ef2ec03a471e18e3b94e9dc2a6 325 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 217 1.8E-47 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4R43_01795 471c529508e73cceef1b1f4b3258166a 387 SUPERFAMILY SSF51604 122 381 8.99E-56 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_01795 471c529508e73cceef1b1f4b3258166a 387 Gene3D G3DSA:3.20.20.120 127 385 1.2E-65 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_01795 471c529508e73cceef1b1f4b3258166a 387 Gene3D G3DSA:3.30.390.10 1 126 1.3E-54 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_01795 471c529508e73cceef1b1f4b3258166a 387 Pfam PF13378 Enolase C-terminal domain-like 164 376 4.9E-41 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_01795 471c529508e73cceef1b1f4b3258166a 387 SUPERFAMILY SSF54826 1 138 7.84E-27 T 14-10-2018 A4R43_01795 471c529508e73cceef1b1f4b3258166a 387 SMART SM00922 161 259 5.2E-17 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_27950 988435dbf9094fe685bf057464c7c658 199 Gene3D G3DSA:1.10.357.10 7 196 6.5E-56 T 14-10-2018 A4R43_27950 988435dbf9094fe685bf057464c7c658 199 SUPERFAMILY SSF46689 2 85 1.59E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_27950 988435dbf9094fe685bf057464c7c658 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.1E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_27950 988435dbf9094fe685bf057464c7c658 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.1E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_27950 988435dbf9094fe685bf057464c7c658 199 SUPERFAMILY SSF48498 80 194 4.24E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_27950 988435dbf9094fe685bf057464c7c658 199 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 84 194 1.0E-29 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_27950 988435dbf9094fe685bf057464c7c658 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.9E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20320 28d3082cd931574be4fa0f0ae8285d1f 286 Gene3D G3DSA:3.40.50.1820 6 273 2.4E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20320 28d3082cd931574be4fa0f0ae8285d1f 286 SUPERFAMILY SSF53474 22 265 5.13E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20320 28d3082cd931574be4fa0f0ae8285d1f 286 Pfam PF12697 Alpha/beta hydrolase family 53 267 1.8E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_03100 7f93c6ae39c1fdf30ace0cd12e95626f 395 SMART SM00331 179 394 1.1E-12 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03100 7f93c6ae39c1fdf30ace0cd12e95626f 395 SUPERFAMILY SSF81606 196 348 2.62E-6 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03100 7f93c6ae39c1fdf30ace0cd12e95626f 395 Gene3D G3DSA:3.60.40.10 176 394 4.6E-42 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_03100 7f93c6ae39c1fdf30ace0cd12e95626f 395 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 208 393 3.9E-32 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_32965 1b66fd4f9f0c8ebdcd4ad67a753f367d 189 Pfam PF00578 AhpC/TSA family 61 167 1.5E-17 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_32965 1b66fd4f9f0c8ebdcd4ad67a753f367d 189 Gene3D G3DSA:3.40.30.10 41 188 6.8E-37 T 14-10-2018 A4R43_32965 1b66fd4f9f0c8ebdcd4ad67a753f367d 189 SUPERFAMILY SSF52833 49 188 5.63E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_32965 1b66fd4f9f0c8ebdcd4ad67a753f367d 189 ProSitePatterns PS00194 Thioredoxin family active site. 78 96 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A4R43_29970 f6fb5e44401abdfc71dbc5e705a69374 271 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 7 258 9.9E-105 T 14-10-2018 IPR017518 Conserved hypothetical protein CHP03084 A4R43_29970 f6fb5e44401abdfc71dbc5e705a69374 271 SUPERFAMILY SSF109854 2 154 1.13E-31 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_29970 f6fb5e44401abdfc71dbc5e705a69374 271 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 225 1.7E-47 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_29970 f6fb5e44401abdfc71dbc5e705a69374 271 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 148 8.5E-29 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_29970 f6fb5e44401abdfc71dbc5e705a69374 271 Gene3D G3DSA:1.20.120.450 2 151 5.7E-19 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_38840 f702918b3f17fdb16615153bf910ebae 474 SUPERFAMILY SSF101908 61 192 1.83E-5 T 14-10-2018 A4R43_38840 f702918b3f17fdb16615153bf910ebae 474 Pfam PF08309 LVIVD repeat 70 103 0.072 T 14-10-2018 IPR013211 LVIVD A4R43_38840 f702918b3f17fdb16615153bf910ebae 474 SUPERFAMILY SSF75011 147 449 1.01E-7 T 14-10-2018 A4R43_24710 84329573bf0c781f8b1168e506f63d5b 165 Gene3D G3DSA:3.90.79.10 4 163 3.6E-23 T 14-10-2018 A4R43_24710 84329573bf0c781f8b1168e506f63d5b 165 Pfam PF00293 NUDIX domain 32 137 1.1E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_24710 84329573bf0c781f8b1168e506f63d5b 165 PRINTS PR00502 NUDIX hydrolase family signature 56 70 1.4E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_24710 84329573bf0c781f8b1168e506f63d5b 165 PRINTS PR00502 NUDIX hydrolase family signature 70 85 1.4E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_24710 84329573bf0c781f8b1168e506f63d5b 165 ProSitePatterns PS00893 Nudix box signature. 61 82 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_24710 84329573bf0c781f8b1168e506f63d5b 165 SUPERFAMILY SSF55811 33 156 4.06E-22 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_25910 c9d4d2ea689a6ac41edcfcd71151e77a 86 SUPERFAMILY SSF54285 5 84 1.03E-15 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4R43_25910 c9d4d2ea689a6ac41edcfcd71151e77a 86 Pfam PF02597 ThiS family 8 86 8.6E-14 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A4R43_25910 c9d4d2ea689a6ac41edcfcd71151e77a 86 Gene3D G3DSA:3.10.20.30 5 86 2.1E-19 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_18990 695c734ee1ed541b84f2f02f6424d33c 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 276 4.5E-33 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_18990 695c734ee1ed541b84f2f02f6424d33c 292 Gene3D G3DSA:1.10.3720.10 80 276 4.4E-33 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_18990 695c734ee1ed541b84f2f02f6424d33c 292 SUPERFAMILY SSF161098 83 266 3.4E-36 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_17715 38eae3e0017707fbed1d398a7c670973 139 PIRSF PIRSF017385 1 139 2.1E-49 T 14-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4R43_17715 38eae3e0017707fbed1d398a7c670973 139 Pfam PF12270 Cytochrome c oxidase subunit IV 1 137 1.5E-52 T 14-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4R43_32845 6997d277fca547d49c5134afaf41dbf7 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.1E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_32845 6997d277fca547d49c5134afaf41dbf7 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.1E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_32845 6997d277fca547d49c5134afaf41dbf7 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.1E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_32845 6997d277fca547d49c5134afaf41dbf7 106 SMART SM00418 3 77 6.5E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_32845 6997d277fca547d49c5134afaf41dbf7 106 Gene3D G3DSA:1.10.10.10 1 104 4.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32845 6997d277fca547d49c5134afaf41dbf7 106 Pfam PF01022 Bacterial regulatory protein, arsR family 11 55 5.0E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_32845 6997d277fca547d49c5134afaf41dbf7 106 SUPERFAMILY SSF46785 6 94 3.95E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_12715 9fafa947ba916680acc83ea81c7a781d 328 SUPERFAMILY SSF53901 35 318 1.92E-20 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12715 9fafa947ba916680acc83ea81c7a781d 328 Gene3D G3DSA:3.40.47.10 2 169 4.4E-20 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12715 9fafa947ba916680acc83ea81c7a781d 328 Gene3D G3DSA:3.40.47.10 183 320 1.4E-14 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_34900 e75f954f5ee1a4b0ebe4cca4727112df 328 Pfam PF00248 Aldo/keto reductase family 16 306 2.1E-77 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_34900 e75f954f5ee1a4b0ebe4cca4727112df 328 Gene3D G3DSA:3.20.20.100 1 326 9.0E-120 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_34900 e75f954f5ee1a4b0ebe4cca4727112df 328 SUPERFAMILY SSF51430 1 308 1.31E-97 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_38475 979c990825d0a6c7387c6dd4db7a75aa 352 PIRSF PIRSF000390 1 352 3.5E-95 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_38475 979c990825d0a6c7387c6dd4db7a75aa 352 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 346 1.0E-98 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_38475 979c990825d0a6c7387c6dd4db7a75aa 352 Gene3D G3DSA:3.40.640.10 2 236 1.1E-85 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_38475 979c990825d0a6c7387c6dd4db7a75aa 352 SUPERFAMILY SSF53383 4 350 2.61E-102 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_38475 979c990825d0a6c7387c6dd4db7a75aa 352 Gene3D G3DSA:3.90.1150.10 237 350 1.3E-22 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_37785 8c4c8fb452b92d95b4051cc5b3a52774 467 SUPERFAMILY SSF53474 53 421 1.8E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_37785 8c4c8fb452b92d95b4051cc5b3a52774 467 Pfam PF00561 alpha/beta hydrolase fold 56 417 2.7E-26 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_08035 d7f8d962b4e0f2b81dc213ae2b5db21b 327 SUPERFAMILY SSF46785 270 321 2.25E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08035 d7f8d962b4e0f2b81dc213ae2b5db21b 327 Gene3D G3DSA:1.10.10.10 250 323 1.3E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08035 d7f8d962b4e0f2b81dc213ae2b5db21b 327 Pfam PF12840 Helix-turn-helix domain 259 306 8.1E-7 T 14-10-2018 A4R43_06780 eb5d1e77acd8b43f22b8f562a13fe27f 319 SUPERFAMILY SSF161098 94 300 4.06E-17 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06780 eb5d1e77acd8b43f22b8f562a13fe27f 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 316 1.5E-34 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_06780 eb5d1e77acd8b43f22b8f562a13fe27f 319 Gene3D G3DSA:1.10.3720.10 90 309 5.1E-20 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_32115 bd6785aa6966168b949d36bf9931c31c 302 Pfam PF00892 EamA-like transporter family 162 292 6.3E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_32115 bd6785aa6966168b949d36bf9931c31c 302 SUPERFAMILY SSF103481 212 296 9.81E-11 T 14-10-2018 A4R43_32115 bd6785aa6966168b949d36bf9931c31c 302 SUPERFAMILY SSF103481 65 153 1.18E-6 T 14-10-2018 A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 SUPERFAMILY SSF52540 637 985 2.1E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 Gene3D G3DSA:1.20.120.850 756 979 3.6E-85 T 14-10-2018 A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 SMART SM00490 845 929 2.3E-21 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 Gene3D G3DSA:3.40.50.10810 525 733 6.9E-69 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 SUPERFAMILY SSF52540 513 732 4.91E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 Pfam PF00176 SNF2 family N-terminal domain 540 801 2.3E-53 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 Pfam PF00271 Helicase conserved C-terminal domain 818 929 3.9E-16 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 SMART SM00487 520 710 1.4E-31 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 Gene3D G3DSA:3.40.50.300 741 943 3.6E-85 T 14-10-2018 A4R43_16775 037ebac22c935aec1e25c68e566d5aff 988 Pfam PF12419 SNF2 Helicase protein 347 480 3.9E-36 T 14-10-2018 IPR022138 Helicase SWF/SNF-related A4R43_08560 a5797ecf4076f2f493cb17769c7d7b81 291 Pfam PF00005 ABC transporter 20 157 7.7E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_08560 a5797ecf4076f2f493cb17769c7d7b81 291 Gene3D G3DSA:3.40.50.300 1 229 7.3E-53 T 14-10-2018 A4R43_08560 a5797ecf4076f2f493cb17769c7d7b81 291 SMART SM00382 28 205 1.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08560 a5797ecf4076f2f493cb17769c7d7b81 291 SUPERFAMILY SSF52540 3 220 2.57E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33380 1d4804377aae92409874ba77a9cea686 311 Gene3D G3DSA:2.130.10.10 54 309 1.9E-38 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_33380 1d4804377aae92409874ba77a9cea686 311 SUPERFAMILY SSF50974 67 299 4.18E-26 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 A4R43_41565 3ec8df3e16c3e50b3f599338ea16b322 338 SUPERFAMILY SSF52733 2 336 7.06E-99 T 14-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_41565 3ec8df3e16c3e50b3f599338ea16b322 338 Gene3D G3DSA:3.40.50.10210 50 322 3.6E-113 T 14-10-2018 A4R43_41565 3ec8df3e16c3e50b3f599338ea16b322 338 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 7 336 2.8E-109 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_41565 3ec8df3e16c3e50b3f599338ea16b322 338 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 5 338 31.449 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_41565 3ec8df3e16c3e50b3f599338ea16b322 338 Gene3D G3DSA:1.10.1610.10 3 331 3.6E-113 T 14-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_41565 3ec8df3e16c3e50b3f599338ea16b322 338 Pfam PF02277 Phosphoribosyltransferase 3 335 4.8E-116 T 14-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4R43_30800 c4fe4870821cc67252bb442f2e633356 521 PIRSF PIRSF010361 22 502 2.8E-163 T 14-10-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane A4R43_30800 c4fe4870821cc67252bb442f2e633356 521 Pfam PF09594 Glycosyltransferase family 87 182 393 9.4E-15 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_34880 43292dfba9fc6bf39096fc9fcc37a7c5 207 Gene3D G3DSA:3.40.50.2020 1 206 5.0E-70 T 14-10-2018 A4R43_34880 43292dfba9fc6bf39096fc9fcc37a7c5 207 Pfam PF14681 Uracil phosphoribosyltransferase 5 206 1.0E-59 T 14-10-2018 A4R43_34880 43292dfba9fc6bf39096fc9fcc37a7c5 207 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 207 39.699 T 14-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4R43_34880 43292dfba9fc6bf39096fc9fcc37a7c5 207 SUPERFAMILY SSF53271 3 205 1.7E-58 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_34880 43292dfba9fc6bf39096fc9fcc37a7c5 207 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 205 4.2E-73 T 14-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4R43_21980 d65b53820d55e2380322ee462e125aa3 158 Gene3D G3DSA:2.40.280.10 3 129 1.1E-51 T 14-10-2018 IPR023620 Small protein B A4R43_21980 d65b53820d55e2380322ee462e125aa3 158 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 1.0E-52 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 A4R43_21980 d65b53820d55e2380322ee462e125aa3 158 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 1.1E-59 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 A4R43_21980 d65b53820d55e2380322ee462e125aa3 158 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site A4R43_21980 d65b53820d55e2380322ee462e125aa3 158 SUPERFAMILY SSF74982 3 133 3.66E-54 T 14-10-2018 IPR023620 Small protein B A4R43_21980 d65b53820d55e2380322ee462e125aa3 158 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 74.249 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 A4R43_21980 d65b53820d55e2380322ee462e125aa3 158 Pfam PF01668 SmpB protein 10 150 4.4E-62 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 A4R43_38935 f7203bbd2c8cfa233afb8de3729cc9cd 177 Gene3D G3DSA:3.40.50.300 1 173 3.5E-39 T 14-10-2018 A4R43_38935 f7203bbd2c8cfa233afb8de3729cc9cd 177 SUPERFAMILY SSF52540 4 168 5.09E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38935 f7203bbd2c8cfa233afb8de3729cc9cd 177 Pfam PF07931 Chloramphenicol phosphotransferase-like protein 6 168 9.4E-11 T 14-10-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 SUPERFAMILY SSF50465 313 415 7.67E-26 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 Pfam PF00009 Elongation factor Tu GTP binding domain 5 208 1.2E-38 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 PRINTS PR00315 GTP-binding elongation factor signature 6 19 8.1E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 PRINTS PR00315 GTP-binding elongation factor signature 65 73 8.1E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 PRINTS PR00315 GTP-binding elongation factor signature 85 95 8.1E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 PRINTS PR00315 GTP-binding elongation factor signature 101 112 8.1E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 PRINTS PR00315 GTP-binding elongation factor signature 138 147 8.1E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 Gene3D G3DSA:2.40.30.10 219 309 1.0E-21 T 14-10-2018 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 415 3.8E-165 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 SUPERFAMILY SSF50447 217 305 1.02E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 Gene3D G3DSA:2.40.30.10 311 415 4.5E-29 T 14-10-2018 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 Gene3D G3DSA:3.40.50.300 2 216 3.4E-64 T 14-10-2018 A4R43_39500 c6cc04254e7bbc97b6ad7d26201fd93c 420 SUPERFAMILY SSF52540 3 229 7.3E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17375 33417487e2a0f8e15fbea38a921a9829 549 SUPERFAMILY SSF52540 79 361 9.83E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17375 33417487e2a0f8e15fbea38a921a9829 549 Pfam PF00270 DEAD/DEAH box helicase 30 196 5.3E-42 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_17375 33417487e2a0f8e15fbea38a921a9829 549 Gene3D G3DSA:3.40.50.300 225 387 2.8E-40 T 14-10-2018 A4R43_17375 33417487e2a0f8e15fbea38a921a9829 549 Gene3D G3DSA:3.40.50.300 2 215 1.2E-66 T 14-10-2018 A4R43_17375 33417487e2a0f8e15fbea38a921a9829 549 Pfam PF00271 Helicase conserved C-terminal domain 240 342 1.2E-22 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_17375 33417487e2a0f8e15fbea38a921a9829 549 SMART SM00490 261 342 5.5E-25 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_17375 33417487e2a0f8e15fbea38a921a9829 549 SMART SM00487 25 227 2.2E-47 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_14220 3f22d3b3b69339d67c19bcefd88a120d 394 SUPERFAMILY SSF63999 178 301 7.59E-20 T 14-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A4R43_14220 3f22d3b3b69339d67c19bcefd88a120d 394 Pfam PF12555 Thiamine pyrophosphokinase C terminal 335 385 1.3E-17 T 14-10-2018 IPR022215 Thiamine pyrophosphokinase C-terminal A4R43_14220 3f22d3b3b69339d67c19bcefd88a120d 394 Gene3D G3DSA:3.40.50.10240 177 255 4.0E-6 T 14-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A4R43_28885 cecbf61f21bb3198f9393ac7c79e6291 539 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 13 503 8.5E-174 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 A4R43_28885 cecbf61f21bb3198f9393ac7c79e6291 539 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 52 503 3.0E-159 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 A4R43_28885 cecbf61f21bb3198f9393ac7c79e6291 539 ProSitePatterns PS01303 BCCT family of transporters signature. 321 330 - T 14-10-2018 IPR018093 BCCT transporter, conserved site A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 PIRSF PIRSF000332 388 441 200.0 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 PIRSF PIRSF000332 282 345 28.0 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 PIRSF PIRSF000332 2 229 1.3E-21 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 SUPERFAMILY SSF51905 6 408 1.4E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 Gene3D G3DSA:3.50.50.60 150 222 9.8E-15 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 209 3.5E-19 T 14-10-2018 A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 1.6E-6 T 14-10-2018 A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.6E-6 T 14-10-2018 A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 Gene3D G3DSA:3.50.50.60 310 483 2.9E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38065 7ae665f222d1ba22c9523973feb9ce39 485 Gene3D G3DSA:3.50.50.60 1 149 6.5E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_15390 7f314e04d42af749ed4aa7764859724e 300 SMART SM00382 26 204 4.3E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_15390 7f314e04d42af749ed4aa7764859724e 300 Pfam PF00005 ABC transporter 17 156 3.5E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_15390 7f314e04d42af749ed4aa7764859724e 300 SUPERFAMILY SSF52540 1 221 5.51E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15390 7f314e04d42af749ed4aa7764859724e 300 Gene3D G3DSA:3.40.50.300 1 226 3.6E-56 T 14-10-2018 A4R43_15390 7f314e04d42af749ed4aa7764859724e 300 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1080 1223 5.5E-42 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 SUPERFAMILY SSF52777 103 346 4.45E-54 T 14-10-2018 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 112 346 2.2E-54 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Gene3D G3DSA:1.10.287.1150 375 456 5.0E-28 T 14-10-2018 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Pfam PF02779 Transketolase, pyrimidine binding domain 883 1075 8.3E-52 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 1 24 3.4E-7 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 PIRSF PIRSF000157 1 1224 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 SMART SM00861 883 1076 7.9E-50 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Gene3D G3DSA:3.30.559.10 93 353 6.8E-53 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Pfam PF00676 Dehydrogenase E1 component 498 822 3.0E-57 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Gene3D G3DSA:3.40.50.12470 842 1099 3.9E-153 T 14-10-2018 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 SUPERFAMILY SSF52518 870 1082 1.47E-44 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Gene3D G3DSA:3.40.50.11610 1019 1221 3.9E-153 T 14-10-2018 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 SUPERFAMILY SSF52518 413 827 5.23E-84 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 380 1222 4.9E-296 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4R43_23050 57e11152e23ea59d14e87e8fe14431a6 1224 Gene3D G3DSA:3.40.50.970 457 824 3.0E-141 T 14-10-2018 A4R43_08470 88ab2f24e0bc357ab372ecd23a38e7b5 117 SUPERFAMILY SSF54909 22 110 1.5E-29 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_08470 88ab2f24e0bc357ab372ecd23a38e7b5 117 Gene3D G3DSA:3.30.70.1060 1 113 1.6E-36 T 14-10-2018 A4R43_08470 88ab2f24e0bc357ab372ecd23a38e7b5 117 Pfam PF03795 YCII-related domain 21 111 1.3E-18 T 14-10-2018 IPR005545 YCII-related A4R43_28775 50a80a0bc90d13da20786b238032c88f 148 SUPERFAMILY SSF160424 11 143 2.75E-16 T 14-10-2018 IPR036170 Probable antitoxin YezG superfamily A4R43_07895 b1fbdfe56dcd73e1eb643cc219f3f7c3 206 SUPERFAMILY SSF52096 34 192 1.54E-23 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_07895 b1fbdfe56dcd73e1eb643cc219f3f7c3 206 Gene3D G3DSA:3.90.226.10 8 205 3.0E-27 T 14-10-2018 A4R43_07895 b1fbdfe56dcd73e1eb643cc219f3f7c3 206 Pfam PF00378 Enoyl-CoA hydratase/isomerase 49 140 2.1E-14 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_08450 785bc925e5c668f2402378e9db3388dd 184 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 121 178 2.1E-22 T 14-10-2018 A4R43_34355 5913a8604eaa445658dd00f8661ccccc 567 Gene3D G3DSA:3.50.50.60 442 527 5.0E-20 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34355 5913a8604eaa445658dd00f8661ccccc 567 Gene3D G3DSA:3.50.50.60 183 331 9.8E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34355 5913a8604eaa445658dd00f8661ccccc 567 Gene3D G3DSA:3.50.50.60 8 161 1.1E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34355 5913a8604eaa445658dd00f8661ccccc 567 SUPERFAMILY SSF51905 7 526 3.13E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34355 5913a8604eaa445658dd00f8661ccccc 567 Pfam PF00732 GMC oxidoreductase 10 279 2.7E-12 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_34355 5913a8604eaa445658dd00f8661ccccc 567 Pfam PF05199 GMC oxidoreductase 464 521 8.2E-14 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_20280 1aa613a24a31b39a7bf69ff941af4886 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 116 8.0E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_20280 1aa613a24a31b39a7bf69ff941af4886 120 Gene3D G3DSA:3.10.180.10 1 120 2.2E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_20280 1aa613a24a31b39a7bf69ff941af4886 120 SUPERFAMILY SSF54593 4 119 2.42E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_36240 ed6258e5d622109f5ff68a58cbc1c985 209 Pfam PF06197 Protein of unknown function (DUF998) 16 196 1.1E-17 T 14-10-2018 IPR009339 Protein of unknown function DUF998 A4R43_38565 e93053dac288f511cd0459b122f02c82 603 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 6 15 - T 14-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 A4R43_38565 e93053dac288f511cd0459b122f02c82 603 Gene3D G3DSA:3.40.50.11260 374 461 3.9E-33 T 14-10-2018 A4R43_38565 e93053dac288f511cd0459b122f02c82 603 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 138 1.1E-12 T 14-10-2018 A4R43_38565 e93053dac288f511cd0459b122f02c82 603 PRINTS PR00775 90kDa heat shock protein signature 56 73 6.3E-48 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4R43_38565 e93053dac288f511cd0459b122f02c82 603 PRINTS PR00775 90kDa heat shock protein signature 153 170 6.3E-48 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4R43_38565 e93053dac288f511cd0459b122f02c82 603 PRINTS PR00775 90kDa heat shock protein signature 74 91 6.3E-48 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4R43_38565 e93053dac288f511cd0459b122f02c82 603 PRINTS PR00775 90kDa heat shock protein signature 176 194 6.3E-48 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4R43_38565 e93053dac288f511cd0459b122f02c82 603 PRINTS PR00775 90kDa heat shock protein signature 7 29 6.3E-48 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4R43_38565 e93053dac288f511cd0459b122f02c82 603 PRINTS PR00775 90kDa heat shock protein signature 103 125 6.3E-48 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4R43_38565 e93053dac288f511cd0459b122f02c82 603 SUPERFAMILY SSF110942 484 599 1.44E-31 T 14-10-2018 IPR037196 HSP90, C-terminal domain A4R43_38565 e93053dac288f511cd0459b122f02c82 603 Pfam PF00183 Hsp90 protein 201 599 1.6E-133 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A4R43_38565 e93053dac288f511cd0459b122f02c82 603 SMART SM00387 8 165 3.2E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_38565 e93053dac288f511cd0459b122f02c82 603 SUPERFAMILY SSF54211 207 460 2.05E-93 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_38565 e93053dac288f511cd0459b122f02c82 603 Gene3D G3DSA:3.30.565.10 1 208 8.8E-66 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_38565 e93053dac288f511cd0459b122f02c82 603 Gene3D G3DSA:3.30.230.80 209 373 2.8E-64 T 14-10-2018 A4R43_38565 e93053dac288f511cd0459b122f02c82 603 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 600 28.612 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A4R43_38565 e93053dac288f511cd0459b122f02c82 603 SUPERFAMILY SSF55874 1 199 1.96E-54 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_38565 e93053dac288f511cd0459b122f02c82 603 PIRSF PIRSF002583 1 602 1.6E-207 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A4R43_38565 e93053dac288f511cd0459b122f02c82 603 Gene3D G3DSA:1.20.120.790 464 600 5.8E-40 T 14-10-2018 IPR037196 HSP90, C-terminal domain A4R43_13000 ee07742c6a5e71cbbd5062130954f726 193 SUPERFAMILY SSF46689 12 70 3.89E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13000 ee07742c6a5e71cbbd5062130954f726 193 Gene3D G3DSA:1.10.10.60 8 57 8.9E-14 T 14-10-2018 A4R43_13000 ee07742c6a5e71cbbd5062130954f726 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 62 3.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13000 ee07742c6a5e71cbbd5062130954f726 193 Gene3D G3DSA:1.10.357.10 59 193 2.2E-19 T 14-10-2018 A4R43_13000 ee07742c6a5e71cbbd5062130954f726 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_19150 0f4c0881a1944f69b88ba894300290e6 124 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 122 38.043 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A4R43_19150 0f4c0881a1944f69b88ba894300290e6 124 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 2 123 2.8E-45 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A4R43_19150 0f4c0881a1944f69b88ba894300290e6 124 SUPERFAMILY SSF51230 2 123 8.9E-40 T 14-10-2018 IPR011053 Single hybrid motif A4R43_19150 0f4c0881a1944f69b88ba894300290e6 124 Gene3D G3DSA:2.40.50.100 1 122 1.7E-46 T 14-10-2018 A4R43_19150 0f4c0881a1944f69b88ba894300290e6 124 Pfam PF01597 Glycine cleavage H-protein 7 123 1.5E-40 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A4R43_19150 0f4c0881a1944f69b88ba894300290e6 124 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4R43_12290 fcc2d4fd997b00c0f01c264f1a3198e4 467 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 464 7.3E-78 T 14-10-2018 IPR007795 Type VII secretion system EccB A4R43_12290 fcc2d4fd997b00c0f01c264f1a3198e4 467 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 4 459 5.2E-81 T 14-10-2018 IPR007795 Type VII secretion system EccB A4R43_12290 fcc2d4fd997b00c0f01c264f1a3198e4 467 Gene3D G3DSA:2.40.50.900 71 147 6.9E-24 T 14-10-2018 A4R43_18205 c4e82e1aef0a50605355ff22377a10c0 370 Pfam PF01266 FAD dependent oxidoreductase 2 348 2.2E-50 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_18205 c4e82e1aef0a50605355ff22377a10c0 370 SUPERFAMILY SSF51905 1 368 5.18E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18205 c4e82e1aef0a50605355ff22377a10c0 370 Gene3D G3DSA:3.50.50.60 3 348 8.0E-74 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18205 c4e82e1aef0a50605355ff22377a10c0 370 Gene3D G3DSA:3.30.9.10 86 309 8.0E-74 T 14-10-2018 A4R43_18205 c4e82e1aef0a50605355ff22377a10c0 370 SUPERFAMILY SSF54373 219 310 3.53E-15 T 14-10-2018 A4R43_06675 2bc8b16e73443430d2fd255091241ced 148 PRINTS PR00502 NUDIX hydrolase family signature 61 76 1.7E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_06675 2bc8b16e73443430d2fd255091241ced 148 PRINTS PR00502 NUDIX hydrolase family signature 47 61 1.7E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_06675 2bc8b16e73443430d2fd255091241ced 148 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_06675 2bc8b16e73443430d2fd255091241ced 148 SUPERFAMILY SSF55811 18 142 1.21E-23 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_06675 2bc8b16e73443430d2fd255091241ced 148 Pfam PF00293 NUDIX domain 28 134 1.5E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_06675 2bc8b16e73443430d2fd255091241ced 148 Gene3D G3DSA:3.90.79.10 20 146 2.1E-20 T 14-10-2018 A4R43_13455 7548cfeccdf7da97809531321a7c1522 329 Gene3D G3DSA:1.10.10.10 5 86 1.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13455 7548cfeccdf7da97809531321a7c1522 329 SUPERFAMILY SSF53335 100 325 7.31E-22 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_13455 7548cfeccdf7da97809531321a7c1522 329 Pfam PF16864 Dimerisation domain 13 89 7.7E-11 T 14-10-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain A4R43_13455 7548cfeccdf7da97809531321a7c1522 329 Pfam PF00891 O-methyltransferase 128 311 5.0E-10 T 14-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 A4R43_13455 7548cfeccdf7da97809531321a7c1522 329 SUPERFAMILY SSF46785 11 83 2.96E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13455 7548cfeccdf7da97809531321a7c1522 329 Gene3D G3DSA:3.40.50.150 98 326 2.4E-32 T 14-10-2018 A4R43_32995 7b6111bd79dbe6908e484a0cc25f2cf3 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 57 1.4E-11 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A4R43_32995 7b6111bd79dbe6908e484a0cc25f2cf3 70 Pfam PF12728 Helix-turn-helix domain 9 58 3.2E-11 T 14-10-2018 A4R43_32995 7b6111bd79dbe6908e484a0cc25f2cf3 70 Gene3D G3DSA:1.10.1660.10 7 64 3.4E-11 T 14-10-2018 A4R43_32995 7b6111bd79dbe6908e484a0cc25f2cf3 70 SUPERFAMILY SSF46955 8 59 2.75E-11 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_28080 ce733522ff0d479d2285fb97966a76f9 299 SUPERFAMILY SSF53448 10 260 2.2E-30 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_28080 ce733522ff0d479d2285fb97966a76f9 299 Pfam PF00535 Glycosyl transferase family 2 13 136 1.1E-11 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_28080 ce733522ff0d479d2285fb97966a76f9 299 Gene3D G3DSA:3.90.550.10 4 220 9.3E-17 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_15360 baab85b5c97cb182100029f91b787fd4 193 Gene3D G3DSA:1.10.357.10 2 193 1.1E-50 T 14-10-2018 A4R43_15360 baab85b5c97cb182100029f91b787fd4 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_15360 baab85b5c97cb182100029f91b787fd4 193 SUPERFAMILY SSF46689 2 85 1.15E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_15360 baab85b5c97cb182100029f91b787fd4 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 4.2E-19 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15360 baab85b5c97cb182100029f91b787fd4 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 9.4E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15360 baab85b5c97cb182100029f91b787fd4 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 9.4E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34650 883078fdde519f89ea9f645e8d333370 253 Gene3D G3DSA:2.60.120.200 40 239 1.0E-6 T 14-10-2018 A4R43_16440 007ac3a3c8fa0b033b0b56e0b6710649 193 TIGRFAM TIGR00077 lspA: signal peptidase II 25 179 3.8E-29 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4R43_16440 007ac3a3c8fa0b033b0b56e0b6710649 193 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 25 182 15.501 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4R43_16440 007ac3a3c8fa0b033b0b56e0b6710649 193 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 114 129 1.5E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4R43_16440 007ac3a3c8fa0b033b0b56e0b6710649 193 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 157 173 1.5E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4R43_16440 007ac3a3c8fa0b033b0b56e0b6710649 193 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 72 80 1.5E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4R43_16440 007ac3a3c8fa0b033b0b56e0b6710649 193 ProSitePatterns PS00855 Signal peptidases II signature. 117 129 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4R43_16440 007ac3a3c8fa0b033b0b56e0b6710649 193 Pfam PF01252 Signal peptidase (SPase) II 33 176 7.6E-31 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4R43_31505 e2661497fe1ccec34b9dc6dfaec032ca 276 PRINTS PR00990 Ribokinase signature 32 51 6.1E-8 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_31505 e2661497fe1ccec34b9dc6dfaec032ca 276 PRINTS PR00990 Ribokinase signature 5 26 6.1E-8 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_31505 e2661497fe1ccec34b9dc6dfaec032ca 276 PRINTS PR00990 Ribokinase signature 195 206 6.1E-8 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_31505 e2661497fe1ccec34b9dc6dfaec032ca 276 Gene3D G3DSA:3.40.1190.20 1 276 2.1E-52 T 14-10-2018 IPR029056 Ribokinase-like A4R43_31505 e2661497fe1ccec34b9dc6dfaec032ca 276 Pfam PF00294 pfkB family carbohydrate kinase 3 182 1.6E-15 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_31505 e2661497fe1ccec34b9dc6dfaec032ca 276 Pfam PF00294 pfkB family carbohydrate kinase 193 266 1.8E-10 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_31505 e2661497fe1ccec34b9dc6dfaec032ca 276 SUPERFAMILY SSF53613 1 274 1.56E-43 T 14-10-2018 IPR029056 Ribokinase-like A4R43_30145 664e8c733b4750c4b729788f92e409f2 265 SUPERFAMILY SSF52540 19 248 3.47E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30145 664e8c733b4750c4b729788f92e409f2 265 Gene3D G3DSA:3.40.50.300 17 259 9.8E-60 T 14-10-2018 A4R43_30145 664e8c733b4750c4b729788f92e409f2 265 Pfam PF00005 ABC transporter 35 182 6.8E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_30145 664e8c733b4750c4b729788f92e409f2 265 SMART SM00382 43 254 1.4E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_30145 664e8c733b4750c4b729788f92e409f2 265 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 Gene3D G3DSA:3.40.50.880 1 203 1.1E-45 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 SUPERFAMILY SSF52317 1 191 3.77E-38 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 SUPERFAMILY SSF46689 214 259 4.42E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 SUPERFAMILY SSF46689 262 312 3.99E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 263 305 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 Pfam PF12833 Helix-turn-helix domain 232 311 1.6E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 Gene3D G3DSA:1.10.10.60 208 315 7.0E-26 T 14-10-2018 A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 SMART SM00342 226 309 2.0E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_07710 a25f884d2f55fa04af0c77a81de8ca04 319 Pfam PF01965 DJ-1/PfpI family 1 170 3.8E-9 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 SUPERFAMILY SSF46689 440 526 1.08E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 Gene3D G3DSA:3.40.50.300 256 401 2.9E-13 T 14-10-2018 A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 Gene3D G3DSA:3.30.450.40 1 133 7.0E-29 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 Gene3D G3DSA:1.10.10.60 483 526 4.4E-15 T 14-10-2018 A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 Pfam PF02954 Bacterial regulatory protein, Fis family 484 522 6.4E-14 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 507 527 5.1E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 490 507 5.1E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 SUPERFAMILY SSF52540 257 470 3.1E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 Gene3D G3DSA:1.10.8.60 402 476 8.0E-11 T 14-10-2018 A4R43_29820 9aa2d06c2a06cd90780eeded9c4928a9 557 Pfam PF14532 Sigma-54 interaction domain 257 358 4.3E-10 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A4R43_01255 b5c1b4f63a05e9c26b82d6bb72212036 115 SUPERFAMILY SSF53041 3 96 6.54E-8 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4R43_01255 b5c1b4f63a05e9c26b82d6bb72212036 115 Gene3D G3DSA:3.40.50.1390 2 106 7.2E-6 T 14-10-2018 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 416 2.5E-28 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 SUPERFAMILY SSF51735 9 188 4.55E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 9 413 1.5E-127 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 9 173 2.9E-52 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 PIRSF PIRSF000124 8 432 1.3E-119 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 SUPERFAMILY SSF52413 308 426 3.14E-30 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 SMART SM00984 316 417 5.0E-38 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 288 4.3E-33 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 PIRSF PIRSF500134 7 434 4.0E-140 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 SUPERFAMILY SSF48179 196 293 2.04E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 Gene3D G3DSA:3.40.50.720 2 196 1.6E-67 T 14-10-2018 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 Gene3D G3DSA:3.40.50.720 227 435 2.1E-65 T 14-10-2018 A4R43_07540 724bcdbed4d4dc8029a2ac330885b895 435 Gene3D G3DSA:1.20.5.100 197 226 4.5E-13 T 14-10-2018 A4R43_15630 2854f2b244563ac98d544411a8d90241 146 Pfam PF12802 MarR family 30 88 6.4E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_15630 2854f2b244563ac98d544411a8d90241 146 Gene3D G3DSA:1.10.10.10 1 136 9.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15630 2854f2b244563ac98d544411a8d90241 146 SUPERFAMILY SSF46785 3 135 7.44E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15630 2854f2b244563ac98d544411a8d90241 146 SMART SM00347 24 127 1.7E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 Gene3D G3DSA:1.10.630.10 11 404 4.3E-126 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 199 221 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 321 336 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 351 362 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 98 109 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 276 287 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 293 320 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 145 161 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 162 177 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00359 B-class P450 signature 342 351 1.6E-61 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 Pfam PF00067 Cytochrome P450 223 372 3.6E-25 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 SUPERFAMILY SSF48264 16 403 8.91E-100 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00385 P450 superfamily signature 351 362 1.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00385 P450 superfamily signature 241 258 1.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00385 P450 superfamily signature 342 351 1.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_03375 82971bc2560552a582c59c4c417a9f06 404 PRINTS PR00385 P450 superfamily signature 276 287 1.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_32700 5af3642e1dc9120bebfa08b3ed6abfbb 143 PIRSF PIRSF017371 1 143 2.4E-56 T 14-10-2018 IPR014488 Uncharacterised conserved protein UCP017371 A4R43_32700 5af3642e1dc9120bebfa08b3ed6abfbb 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 142 6.4E-22 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_32700 5af3642e1dc9120bebfa08b3ed6abfbb 143 SUPERFAMILY SSF55961 7 142 2.45E-19 T 14-10-2018 A4R43_32700 5af3642e1dc9120bebfa08b3ed6abfbb 143 Gene3D G3DSA:3.30.530.20 6 143 7.7E-14 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_36940 8cd5b8cc12629e050e12db8c3fe40477 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 69 6.4E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_36940 8cd5b8cc12629e050e12db8c3fe40477 304 Gene3D G3DSA:1.10.10.10 8 95 4.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36940 8cd5b8cc12629e050e12db8c3fe40477 304 Pfam PF03466 LysR substrate binding domain 96 299 2.9E-44 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_36940 8cd5b8cc12629e050e12db8c3fe40477 304 Gene3D G3DSA:3.40.190.10 171 277 2.8E-36 T 14-10-2018 A4R43_36940 8cd5b8cc12629e050e12db8c3fe40477 304 SUPERFAMILY SSF53850 97 301 1.16E-38 T 14-10-2018 A4R43_36940 8cd5b8cc12629e050e12db8c3fe40477 304 Gene3D G3DSA:3.40.190.10 99 287 2.8E-36 T 14-10-2018 A4R43_36940 8cd5b8cc12629e050e12db8c3fe40477 304 SUPERFAMILY SSF46785 10 117 1.09E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40935 82205dd050405b61f8b46171547cbc26 250 PRINTS PR00164 ABC-2 type transport system membrane protein signature 174 193 6.4E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_40935 82205dd050405b61f8b46171547cbc26 250 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 77 6.4E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_40935 82205dd050405b61f8b46171547cbc26 250 PRINTS PR00164 ABC-2 type transport system membrane protein signature 98 123 6.4E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_40935 82205dd050405b61f8b46171547cbc26 250 Pfam PF01061 ABC-2 type transporter 9 216 3.2E-25 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_40935 82205dd050405b61f8b46171547cbc26 250 PIRSF PIRSF006648 1 250 6.4E-62 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_22585 cb532909fc1e1ff40c6aa4b198b76c6e 355 Gene3D G3DSA:3.40.50.2300 155 355 8.1E-119 T 14-10-2018 A4R43_22585 cb532909fc1e1ff40c6aa4b198b76c6e 355 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 56 355 2.2E-113 T 14-10-2018 IPR013459 Rhamnose ABC transporter, substrate-binding protein RhaS GO:0015762 A4R43_22585 cb532909fc1e1ff40c6aa4b198b76c6e 355 Gene3D G3DSA:3.40.50.2300 55 339 8.1E-119 T 14-10-2018 A4R43_22585 cb532909fc1e1ff40c6aa4b198b76c6e 355 Pfam PF13407 Periplasmic binding protein domain 57 312 1.7E-52 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_22585 cb532909fc1e1ff40c6aa4b198b76c6e 355 SUPERFAMILY SSF53822 53 355 7.85E-61 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_35030 6370adaca025d2790dcea263d993c858 173 Pfam PF13302 Acetyltransferase (GNAT) domain 10 151 6.2E-22 T 14-10-2018 IPR000182 GNAT domain A4R43_35030 6370adaca025d2790dcea263d993c858 173 Gene3D G3DSA:3.40.630.30 1 167 2.6E-32 T 14-10-2018 A4R43_35030 6370adaca025d2790dcea263d993c858 173 SUPERFAMILY SSF55729 10 155 3.66E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_19100 5b96955846882ba26836de2a554883f1 407 Gene3D G3DSA:3.50.50.60 7 313 1.6E-103 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_19100 5b96955846882ba26836de2a554883f1 407 Gene3D G3DSA:3.50.50.60 115 240 1.6E-103 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 3.4E-19 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 3.4E-19 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.4E-19 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 3.4E-19 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 Pfam PF14759 Reductase C-terminal 324 399 3.9E-11 T 14-10-2018 IPR028202 Reductase, C-terminal A4R43_19100 5b96955846882ba26836de2a554883f1 407 SUPERFAMILY SSF51905 3 314 1.09E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_19100 5b96955846882ba26836de2a554883f1 407 SUPERFAMILY SSF55424 317 402 3.71E-20 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 5.9E-27 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 5.9E-27 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 5.9E-27 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 5.9E-27 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.9E-27 T 14-10-2018 A4R43_19100 5b96955846882ba26836de2a554883f1 407 Gene3D G3DSA:3.30.390.30 324 405 1.2E-16 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_19100 5b96955846882ba26836de2a554883f1 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 305 5.9E-61 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 Gene3D G3DSA:1.10.246.130 287 402 3.4E-34 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 144 162 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 472 487 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 496 513 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 70 95 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 162 181 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 412 430 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 436 454 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 301 320 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 271 287 1.7E-67 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 Gene3D G3DSA:3.60.20.40 412 595 6.0E-52 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 Pfam PF01019 Gamma-glutamyltranspeptidase 63 591 2.0E-148 T 14-10-2018 A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 SUPERFAMILY SSF56235 43 591 4.19E-152 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_04785 83013a880ea926fb4651e0912c6bd418 604 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 50 585 1.6E-125 T 14-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 A4R43_03030 4c01015befe37e1930553d0027f5ebe6 302 Gene3D G3DSA:3.40.190.10 92 284 2.8E-43 T 14-10-2018 A4R43_03030 4c01015befe37e1930553d0027f5ebe6 302 SUPERFAMILY SSF53850 88 298 1.86E-37 T 14-10-2018 A4R43_03030 4c01015befe37e1930553d0027f5ebe6 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.8E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_03030 4c01015befe37e1930553d0027f5ebe6 302 Gene3D G3DSA:1.10.10.10 1 88 2.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03030 4c01015befe37e1930553d0027f5ebe6 302 Gene3D G3DSA:3.40.190.10 170 270 2.8E-43 T 14-10-2018 A4R43_03030 4c01015befe37e1930553d0027f5ebe6 302 SUPERFAMILY SSF46785 1 110 1.03E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03030 4c01015befe37e1930553d0027f5ebe6 302 Pfam PF03466 LysR substrate binding domain 88 294 9.4E-42 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 33 476 5.8E-147 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 Gene3D G3DSA:1.20.210.10 17 537 1.4E-203 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 140 152 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 201 220 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 251 272 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 312 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 230 251 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 354 372 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 70 93 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 172 190 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 432 453 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 23 48 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 121 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 319 340 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 382 401 5.0E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 253 307 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 SUPERFAMILY SSF81442 22 531 1.14E-173 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15550 b2a554dd523b7feaa08baf79caaf0cc4 578 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 25 528 6.9E-215 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4R43_41300 1f485be98f800334dcbf7d5eadd0c150 216 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 81 103 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4R43_41300 1f485be98f800334dcbf7d5eadd0c150 216 PIRSF PIRSF000847 30 212 1.1E-46 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A4R43_41300 1f485be98f800334dcbf7d5eadd0c150 216 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 33 204 4.9E-38 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A4R43_41300 1f485be98f800334dcbf7d5eadd0c150 216 Gene3D G3DSA:1.20.120.1760 32 203 4.5E-9 T 14-10-2018 A4R43_41300 1f485be98f800334dcbf7d5eadd0c150 216 Pfam PF01066 CDP-alcohol phosphatidyltransferase 33 103 3.9E-14 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4R43_39130 d916ef9656c6fc9f295dd594b9eb4dfd 294 Gene3D G3DSA:3.40.50.1110 31 290 2.2E-67 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_39130 d916ef9656c6fc9f295dd594b9eb4dfd 294 SUPERFAMILY SSF52266 34 289 3.16E-58 T 14-10-2018 A4R43_39130 d916ef9656c6fc9f295dd594b9eb4dfd 294 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 37 277 1.7E-27 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_22895 fd8c5c68bc3ea46d670dedd84b529fe6 351 SUPERFAMILY SSF53474 43 346 2.29E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22895 fd8c5c68bc3ea46d670dedd84b529fe6 351 Gene3D G3DSA:3.40.50.1820 39 351 1.9E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_33445 6aa46cdbe053e14244ca763ce8e521c2 220 SUPERFAMILY SSF46689 24 97 5.99E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_33445 6aa46cdbe053e14244ca763ce8e521c2 220 Gene3D G3DSA:1.10.10.60 21 73 4.5E-19 T 14-10-2018 A4R43_33445 6aa46cdbe053e14244ca763ce8e521c2 220 Gene3D G3DSA:1.10.357.10 74 220 1.9E-19 T 14-10-2018 A4R43_33445 6aa46cdbe053e14244ca763ce8e521c2 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 1.1E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33445 6aa46cdbe053e14244ca763ce8e521c2 220 SUPERFAMILY SSF48498 107 219 8.43E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_33445 6aa46cdbe053e14244ca763ce8e521c2 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 2.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33445 6aa46cdbe053e14244ca763ce8e521c2 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 2.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33030 249cd2a92696fc237db5b7cffbab23b3 307 Gene3D G3DSA:3.90.226.10 7 246 3.9E-86 T 14-10-2018 A4R43_33030 249cd2a92696fc237db5b7cffbab23b3 307 SUPERFAMILY SSF52096 37 305 1.32E-73 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_33030 249cd2a92696fc237db5b7cffbab23b3 307 TIGRFAM TIGR01929 menB: naphthoate synthase 23 301 2.2E-127 T 14-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A4R43_33030 249cd2a92696fc237db5b7cffbab23b3 307 Pfam PF00378 Enoyl-CoA hydratase/isomerase 38 301 1.5E-49 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_33030 249cd2a92696fc237db5b7cffbab23b3 307 Gene3D G3DSA:1.10.12.10 247 295 6.9E-25 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_33030 249cd2a92696fc237db5b7cffbab23b3 307 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 15 306 52.347 T 14-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A4R43_36120 a1f1612689d961685842417685e6c1d9 274 Gene3D G3DSA:3.30.70.20 207 270 8.1E-16 T 14-10-2018 A4R43_36120 a1f1612689d961685842417685e6c1d9 274 SUPERFAMILY SSF54862 210 269 5.76E-9 T 14-10-2018 A4R43_36120 a1f1612689d961685842417685e6c1d9 274 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 214 268 1.4E-10 T 14-10-2018 A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 Gene3D G3DSA:3.30.9.10 127 334 2.7E-47 T 14-10-2018 A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 SUPERFAMILY SSF51905 33 393 2.2E-31 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 SUPERFAMILY SSF50022 427 501 3.01E-21 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 Gene3D G3DSA:3.50.50.60 34 376 2.7E-47 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 Gene3D G3DSA:2.102.10.10 414 503 1.2E-22 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 Pfam PF01266 FAD dependent oxidoreductase 34 375 2.4E-40 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 Pfam PF00355 Rieske [2Fe-2S] domain 433 501 2.8E-11 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 PRINTS PR00162 Rieske 2Fe-2S subunit signature 455 466 5.4E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 PRINTS PR00162 Rieske 2Fe-2S subunit signature 476 488 5.4E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4R43_06235 17e912e9ab63aac9694c14c69f34e681 503 PRINTS PR00162 Rieske 2Fe-2S subunit signature 488 500 5.4E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 SMART SM00382 351 572 3.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 SMART SM00382 32 242 1.8E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 Gene3D G3DSA:3.40.50.300 1 314 6.0E-78 T 14-10-2018 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 Gene3D G3DSA:3.40.50.300 316 581 1.6E-76 T 14-10-2018 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 546 573 0.29 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 276 6.7E-7 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 Pfam PF00005 ABC transporter 343 495 1.6E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 ProSitePatterns PS00211 ABC transporters family signature. 467 481 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 Pfam PF00005 ABC transporter 24 192 3.9E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 SUPERFAMILY SSF52540 3 264 5.33E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13460 6e170fcb94c58716fd5940ce9eb6925c 584 SUPERFAMILY SSF52540 319 566 8.61E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 Gene3D G3DSA:3.40.350.10 6 136 3.9E-29 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 SUPERFAMILY SSF55920 96 358 1.7E-74 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 SUPERFAMILY SSF53092 6 136 4.06E-24 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 295 307 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 Pfam PF00557 Metallopeptidase family M24 145 348 7.9E-63 T 14-10-2018 IPR000994 Peptidase M24 A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 137 9.4E-25 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 210 2.6E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 317 329 2.6E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 219 235 2.6E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4R43_04690 9b94d14b117ab5109f18d2f8ee759d84 365 Gene3D G3DSA:3.90.230.10 137 365 2.5E-78 T 14-10-2018 A4R43_00665 e53c653b2351935eb583500faa2f96ae 257 Pfam PF13349 Putative adhesin 39 254 5.5E-9 T 14-10-2018 IPR025164 Putative adhesin A4R43_27115 d78925e6b35fd0b2730c4dfaf739db1c 229 Pfam PF11010 Protein of unknown function (DUF2848) 27 219 8.8E-73 T 14-10-2018 IPR021269 Protein of unknown function DUF2848 A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 Pfam PF00994 Probable molybdopterin binding domain 6 140 2.9E-25 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 Gene3D G3DSA:3.90.1170.40 159 303 1.2E-43 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 Gene3D G3DSA:3.40.980.10 1 158 8.4E-50 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 SUPERFAMILY SSF54690 171 302 4.18E-37 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 Pfam PF02391 MoaE protein 172 284 4.1E-33 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 138 2.1E-26 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 SUPERFAMILY SSF53218 2 152 1.19E-38 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 SMART SM00852 5 147 5.2E-17 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_25925 e344a850dc6a8dd2dd233b68199787ff 304 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 63 76 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A4R43_08985 3a0bc7b600315500548b4d757600fcc6 342 SUPERFAMILY SSF161098 115 325 1.13E-16 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_08985 3a0bc7b600315500548b4d757600fcc6 342 Gene3D G3DSA:1.10.3720.10 110 336 1.4E-21 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_08985 3a0bc7b600315500548b4d757600fcc6 342 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 340 1.1E-39 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_17305 b346fafe3589beab889e52126c500504 209 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 208 31.995 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4R43_17305 b346fafe3589beab889e52126c500504 209 PIRSF PIRSF000495 2 209 1.1E-63 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4R43_17305 b346fafe3589beab889e52126c500504 209 Pfam PF00117 Glutamine amidotransferase class-I 6 203 1.9E-17 T 14-10-2018 IPR017926 Glutamine amidotransferase A4R43_17305 b346fafe3589beab889e52126c500504 209 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 206 3.4E-65 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4R43_17305 b346fafe3589beab889e52126c500504 209 Gene3D G3DSA:3.40.50.880 1 208 6.9E-68 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_17305 b346fafe3589beab889e52126c500504 209 SUPERFAMILY SSF52317 3 207 6.88E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_01850 f07c834e675163bc6f9b7bed59150e11 474 Gene3D G3DSA:1.20.1250.20 256 471 5.2E-16 T 14-10-2018 A4R43_01850 f07c834e675163bc6f9b7bed59150e11 474 Pfam PF07690 Major Facilitator Superfamily 20 411 2.8E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_01850 f07c834e675163bc6f9b7bed59150e11 474 SUPERFAMILY SSF103473 10 465 9.94E-59 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_01850 f07c834e675163bc6f9b7bed59150e11 474 Gene3D G3DSA:1.20.1720.10 15 225 7.7E-44 T 14-10-2018 A4R43_31425 992eb54ee9c6ea794ecffdde30dd8308 154 Pfam PF12802 MarR family 35 93 5.7E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31425 992eb54ee9c6ea794ecffdde30dd8308 154 SUPERFAMILY SSF46785 10 143 3.26E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31425 992eb54ee9c6ea794ecffdde30dd8308 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.3E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31425 992eb54ee9c6ea794ecffdde30dd8308 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.3E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31425 992eb54ee9c6ea794ecffdde30dd8308 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.3E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31425 992eb54ee9c6ea794ecffdde30dd8308 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.3E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31425 992eb54ee9c6ea794ecffdde30dd8308 154 SMART SM00347 29 129 1.0E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31425 992eb54ee9c6ea794ecffdde30dd8308 154 Gene3D G3DSA:1.10.10.10 1 145 4.7E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17830 52ac96ef8262c85f642bf6fec710c5f6 176 SUPERFAMILY SSF46689 1 70 4.39E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17830 52ac96ef8262c85f642bf6fec710c5f6 176 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 45 1.1E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17830 52ac96ef8262c85f642bf6fec710c5f6 176 Gene3D G3DSA:1.10.357.10 1 174 7.6E-36 T 14-10-2018 A4R43_17830 52ac96ef8262c85f642bf6fec710c5f6 176 SUPERFAMILY SSF48498 66 175 4.13E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_17830 52ac96ef8262c85f642bf6fec710c5f6 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 12 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17830 52ac96ef8262c85f642bf6fec710c5f6 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 43 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16960 08722cc052e323cb6757232a0667c9dd 178 Hamap MF_01114 Regulatory protein RecX [recX]. 1 165 14.541 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 A4R43_16960 08722cc052e323cb6757232a0667c9dd 178 Gene3D G3DSA:1.10.10.10 64 109 1.0E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_16960 08722cc052e323cb6757232a0667c9dd 178 Pfam PF02631 RecX family 40 160 2.7E-25 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 A4R43_16960 08722cc052e323cb6757232a0667c9dd 178 Gene3D G3DSA:1.10.10.2800 4 63 2.8E-7 T 14-10-2018 A4R43_19140 03908d35793d4bbe425577baa5a88395 333 Pfam PF04055 Radical SAM superfamily 81 234 7.2E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_19140 03908d35793d4bbe425577baa5a88395 333 TIGRFAM TIGR00510 lipA: lipoyl synthase 17 303 8.2E-98 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_19140 03908d35793d4bbe425577baa5a88395 333 Gene3D G3DSA:3.20.20.70 76 258 7.9E-15 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_19140 03908d35793d4bbe425577baa5a88395 333 SMART SM00729 71 277 1.0E-14 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_19140 03908d35793d4bbe425577baa5a88395 333 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 4.2E-7 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_19140 03908d35793d4bbe425577baa5a88395 333 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 140.621 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_19140 03908d35793d4bbe425577baa5a88395 333 SUPERFAMILY SSF102114 35 296 2.49E-61 T 14-10-2018 A4R43_19140 03908d35793d4bbe425577baa5a88395 333 PIRSF PIRSF005963 3 318 4.5E-120 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_06850 b05bae24e61ce8bc3715a9eb94a1103f 118 SUPERFAMILY SSF52091 8 112 5.49E-20 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_06850 b05bae24e61ce8bc3715a9eb94a1103f 118 Gene3D G3DSA:3.30.750.24 4 115 2.3E-25 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_06850 b05bae24e61ce8bc3715a9eb94a1103f 118 Pfam PF13466 STAS domain 16 93 8.7E-17 T 14-10-2018 IPR002645 STAS domain A4R43_06850 b05bae24e61ce8bc3715a9eb94a1103f 118 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 7 106 1.1E-19 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_17420 81b2bb2441912247837aab321a579628 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 146 4.7E-62 T 14-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 A4R43_17420 81b2bb2441912247837aab321a579628 153 SUPERFAMILY SSF46955 8 126 2.64E-29 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_17420 81b2bb2441912247837aab321a579628 153 Gene3D G3DSA:1.10.1660.10 2 131 1.8E-35 T 14-10-2018 A4R43_17420 81b2bb2441912247837aab321a579628 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 1.2E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_17420 81b2bb2441912247837aab321a579628 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 1.2E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_17420 81b2bb2441912247837aab321a579628 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 1.2E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_17420 81b2bb2441912247837aab321a579628 153 Pfam PF00376 MerR family regulatory protein 9 45 4.4E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_17420 81b2bb2441912247837aab321a579628 153 SMART SM00422 8 76 2.0E-24 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_17420 81b2bb2441912247837aab321a579628 153 Pfam PF09278 MerR, DNA binding 50 115 1.0E-20 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding A4R43_01975 64013379310df450a005afb7e2fb3d53 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 1.2E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_01975 64013379310df450a005afb7e2fb3d53 225 SMART SM00448 2 112 1.4E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_01975 64013379310df450a005afb7e2fb3d53 225 SUPERFAMILY SSF46894 118 220 1.9E-30 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_01975 64013379310df450a005afb7e2fb3d53 225 Pfam PF00072 Response regulator receiver domain 4 112 1.0E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_01975 64013379310df450a005afb7e2fb3d53 225 Gene3D G3DSA:3.40.50.2300 2 123 3.6E-37 T 14-10-2018 A4R43_01975 64013379310df450a005afb7e2fb3d53 225 SUPERFAMILY SSF52172 3 121 5.98E-40 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_01975 64013379310df450a005afb7e2fb3d53 225 Gene3D G3DSA:1.10.10.10 124 224 7.6E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01975 64013379310df450a005afb7e2fb3d53 225 SMART SM00862 144 220 4.2E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37635 13b87d0b67ff3ed06c89df37d4bc5e7d 267 Gene3D G3DSA:3.30.559.10 17 134 2.2E-7 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_37635 13b87d0b67ff3ed06c89df37d4bc5e7d 267 SUPERFAMILY SSF52777 8 249 4.08E-31 T 14-10-2018 A4R43_37635 13b87d0b67ff3ed06c89df37d4bc5e7d 267 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 172 250 5.8E-16 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A4R43_37635 13b87d0b67ff3ed06c89df37d4bc5e7d 267 Gene3D G3DSA:3.30.559.10 161 251 6.3E-19 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 372 1.3E-118 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 SMART SM01209 105 268 0.0055 T 14-10-2018 A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 Gene3D G3DSA:3.30.470.20 110 365 2.4E-87 T 14-10-2018 A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 SUPERFAMILY SSF51246 311 389 3.22E-17 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 SUPERFAMILY SSF56059 106 306 5.13E-59 T 14-10-2018 A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 Pfam PF02222 ATP-grasp domain 116 286 2.3E-49 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 SUPERFAMILY SSF52440 7 101 7.48E-22 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 Gene3D G3DSA:3.30.1490.20 121 186 2.4E-87 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 Gene3D G3DSA:3.40.50.20 7 109 1.6E-28 T 14-10-2018 A4R43_35300 8c6f7af87bc2d8003c3db6c120b447d3 394 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 9 368 38.79 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A4R43_17995 5ceda6e170109a3f3549d45ec26d4a5c 274 SUPERFAMILY SSF103481 196 273 1.7E-9 T 14-10-2018 A4R43_17995 5ceda6e170109a3f3549d45ec26d4a5c 274 SUPERFAMILY SSF103481 57 134 1.7E-7 T 14-10-2018 A4R43_17995 5ceda6e170109a3f3549d45ec26d4a5c 274 Pfam PF00892 EamA-like transporter family 1 130 2.2E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_17995 5ceda6e170109a3f3549d45ec26d4a5c 274 Pfam PF00892 EamA-like transporter family 144 272 9.2E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_09630 4178a25ac3eaa6061a56411f8a7c05fb 197 Gene3D G3DSA:3.30.1360.120 113 190 2.6E-49 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4R43_09630 4178a25ac3eaa6061a56411f8a7c05fb 197 Pfam PF04268 Sarcosine oxidase, gamma subunit family 47 189 3.2E-27 T 14-10-2018 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 A4R43_09630 4178a25ac3eaa6061a56411f8a7c05fb 197 SUPERFAMILY SSF103025 69 191 8.44E-14 T 14-10-2018 A4R43_09630 4178a25ac3eaa6061a56411f8a7c05fb 197 Gene3D G3DSA:3.30.70.1520 34 112 2.6E-49 T 14-10-2018 A4R43_37285 094b5eadd3b5ea0302222dc3458ee3ec 84 ProSitePatterns PS00012 Phosphopantetheine attachment site. 35 50 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_37285 094b5eadd3b5ea0302222dc3458ee3ec 84 SUPERFAMILY SSF47336 10 81 6.67E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37285 094b5eadd3b5ea0302222dc3458ee3ec 84 Pfam PF00550 Phosphopantetheine attachment site 14 74 6.7E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37285 094b5eadd3b5ea0302222dc3458ee3ec 84 Gene3D G3DSA:1.10.1200.10 2 83 9.4E-18 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37285 094b5eadd3b5ea0302222dc3458ee3ec 84 SMART SM00823 Phosphopantetheine attachment site 11 81 0.004 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_31360 a0728bc321ba3d5e8e2daa45134dc8ce 108 SUPERFAMILY SSF103481 6 105 1.57E-14 T 14-10-2018 A4R43_31360 a0728bc321ba3d5e8e2daa45134dc8ce 108 Gene3D G3DSA:1.10.3730.20 1 108 8.0E-31 T 14-10-2018 A4R43_31360 a0728bc321ba3d5e8e2daa45134dc8ce 108 Pfam PF00893 Small Multidrug Resistance protein 4 95 5.8E-23 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A4R43_05865 63660b742716e2436c6f8d52dd5ae7d1 156 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 10 150 3.2E-41 T 14-10-2018 A4R43_05865 63660b742716e2436c6f8d52dd5ae7d1 156 Gene3D G3DSA:1.10.10.1590 2 68 8.3E-13 T 14-10-2018 A4R43_05865 63660b742716e2436c6f8d52dd5ae7d1 156 SUPERFAMILY SSF52833 4 154 8.5E-45 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_05865 63660b742716e2436c6f8d52dd5ae7d1 156 Gene3D G3DSA:3.40.30.10 69 150 3.2E-21 T 14-10-2018 A4R43_05865 63660b742716e2436c6f8d52dd5ae7d1 156 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 109 127 - T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_05865 63660b742716e2436c6f8d52dd5ae7d1 156 PIRSF PIRSF000216 1 156 7.2E-46 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_10060 03ef8272754ac797caa822fd509adf7a 256 Gene3D G3DSA:3.40.50.150 68 241 5.5E-36 T 14-10-2018 A4R43_10060 03ef8272754ac797caa822fd509adf7a 256 Pfam PF08241 Methyltransferase domain 99 206 3.4E-20 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_10060 03ef8272754ac797caa822fd509adf7a 256 SUPERFAMILY SSF53335 77 245 1.27E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_10060 03ef8272754ac797caa822fd509adf7a 256 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 196 210 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 Gene3D G3DSA:1.20.910.10 12 222 3.3E-60 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 SUPERFAMILY SSF48613 13 216 4.03E-53 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 PIRSF PIRSF000343 2 223 6.9E-60 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 Pfam PF01126 Heme oxygenase 13 212 3.5E-46 T 14-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 PRINTS PR00088 Haem oxygenase signature 48 73 1.0E-27 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 PRINTS PR00088 Haem oxygenase signature 73 98 1.0E-27 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 PRINTS PR00088 Haem oxygenase signature 13 38 1.0E-27 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 PRINTS PR00088 Haem oxygenase signature 167 188 1.0E-27 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 PRINTS PR00088 Haem oxygenase signature 125 146 1.0E-27 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25760 124fe148e361106e41eb2e96139b2e69 223 PRINTS PR00088 Haem oxygenase signature 199 217 1.0E-27 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_25145 5e1158e3fb9501f2dbe1d702b9929cf6 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 187 5.2E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_25145 5e1158e3fb9501f2dbe1d702b9929cf6 217 Pfam PF00072 Response regulator receiver domain 9 118 1.2E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25145 5e1158e3fb9501f2dbe1d702b9929cf6 217 SUPERFAMILY SSF52172 7 133 5.27E-14 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_25145 5e1158e3fb9501f2dbe1d702b9929cf6 217 SUPERFAMILY SSF46894 138 211 1.56E-8 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_25145 5e1158e3fb9501f2dbe1d702b9929cf6 217 SMART SM00448 6 118 1.1E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25145 5e1158e3fb9501f2dbe1d702b9929cf6 217 Gene3D G3DSA:3.40.50.2300 3 138 1.5E-11 T 14-10-2018 A4R43_25145 5e1158e3fb9501f2dbe1d702b9929cf6 217 Gene3D G3DSA:1.10.10.10 139 211 5.7E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25145 5e1158e3fb9501f2dbe1d702b9929cf6 217 SMART SM00421 144 201 0.0059 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_17300 2db4ccfb113085000e217e08ce573146 244 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 243 2.2E-124 T 14-10-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 A4R43_17300 2db4ccfb113085000e217e08ce573146 244 SUPERFAMILY SSF51366 2 240 4.44E-61 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4R43_17300 2db4ccfb113085000e217e08ce573146 244 Gene3D G3DSA:3.20.20.70 1 244 7.6E-91 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17300 2db4ccfb113085000e217e08ce573146 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 241 32.665 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A4R43_17300 2db4ccfb113085000e217e08ce573146 244 Pfam PF00977 Histidine biosynthesis protein 5 234 2.2E-63 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A4R43_26715 6d93107bc4e29701737190866206e20c 276 Pfam PF02146 Sir2 family 23 185 5.3E-17 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 A4R43_26715 6d93107bc4e29701737190866206e20c 276 Gene3D G3DSA:3.30.1600.10 32 189 4.6E-40 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A4R43_26715 6d93107bc4e29701737190866206e20c 276 Gene3D G3DSA:3.40.50.1220 16 250 4.6E-40 T 14-10-2018 A4R43_26715 6d93107bc4e29701737190866206e20c 276 SUPERFAMILY SSF52467 4 272 2.99E-59 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_30015 00509d79b6afb818bee15844b8a7402d 518 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 498 1.1E-26 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_30015 00509d79b6afb818bee15844b8a7402d 518 SUPERFAMILY SSF56801 7 512 1.07E-163 T 14-10-2018 A4R43_30015 00509d79b6afb818bee15844b8a7402d 518 Gene3D G3DSA:3.30.300.310 408 513 2.8E-39 T 14-10-2018 A4R43_30015 00509d79b6afb818bee15844b8a7402d 518 Pfam PF00501 AMP-binding enzyme 16 412 5.1E-109 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_30015 00509d79b6afb818bee15844b8a7402d 518 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_30015 00509d79b6afb818bee15844b8a7402d 518 Gene3D G3DSA:3.40.50.12780 4 405 1.1E-125 T 14-10-2018 A4R43_31255 95411ff6f217b9131042a7702767a762 165 SUPERFAMILY SSF88659 96 157 2.06E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_31255 95411ff6f217b9131042a7702767a762 165 SUPERFAMILY SSF88946 5 88 1.29E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31255 95411ff6f217b9131042a7702767a762 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 156 1.5E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_31255 95411ff6f217b9131042a7702767a762 165 Pfam PF08281 Sigma-70, region 4 103 155 1.0E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_31255 95411ff6f217b9131042a7702767a762 165 Pfam PF04542 Sigma-70 region 2 9 75 1.7E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31255 95411ff6f217b9131042a7702767a762 165 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 157 7.7E-45 T 14-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4R43_31255 95411ff6f217b9131042a7702767a762 165 Gene3D G3DSA:1.10.10.10 81 162 1.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31255 95411ff6f217b9131042a7702767a762 165 Gene3D G3DSA:1.10.1740.10 3 77 3.1E-11 T 14-10-2018 A4R43_39655 f7d4c7ebea23d9abd2f5e9f976aaa866 358 SUPERFAMILY SSF52540 134 302 2.24E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39655 f7d4c7ebea23d9abd2f5e9f976aaa866 358 Gene3D G3DSA:3.40.50.300 132 338 5.8E-77 T 14-10-2018 A4R43_39655 f7d4c7ebea23d9abd2f5e9f976aaa866 358 Pfam PF02562 PhoH-like protein 135 338 4.1E-95 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 A4R43_05055 6c3626d5c729785c2addcabb45fe5704 256 SMART SM00382 32 225 3.3E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05055 6c3626d5c729785c2addcabb45fe5704 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 1.1E-104 T 14-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A4R43_05055 6c3626d5c729785c2addcabb45fe5704 256 SUPERFAMILY SSF52540 4 234 1.93E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05055 6c3626d5c729785c2addcabb45fe5704 256 Gene3D G3DSA:3.40.50.300 3 248 2.9E-51 T 14-10-2018 A4R43_05055 6c3626d5c729785c2addcabb45fe5704 256 Pfam PF00005 ABC transporter 23 174 1.3E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_41695 1ac0c489502f8af9c57eaedb6e65f7c0 574 Pfam PF00664 ABC transporter transmembrane region 27 298 7.1E-30 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_41695 1ac0c489502f8af9c57eaedb6e65f7c0 574 SMART SM00382 365 546 4.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_41695 1ac0c489502f8af9c57eaedb6e65f7c0 574 Pfam PF00005 ABC transporter 356 500 3.0E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_41695 1ac0c489502f8af9c57eaedb6e65f7c0 574 Gene3D G3DSA:1.20.1560.10 5 329 5.0E-62 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_41695 1ac0c489502f8af9c57eaedb6e65f7c0 574 Gene3D G3DSA:3.40.50.300 336 573 3.1E-62 T 14-10-2018 A4R43_41695 1ac0c489502f8af9c57eaedb6e65f7c0 574 SUPERFAMILY SSF52540 334 570 4.55E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41695 1ac0c489502f8af9c57eaedb6e65f7c0 574 SUPERFAMILY SSF90123 13 330 3.27E-61 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_14280 1a5614e5ff01e0bc22f794f14feeb78f 205 Gene3D G3DSA:3.10.180.10 2 150 3.3E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_14280 1a5614e5ff01e0bc22f794f14feeb78f 205 Pfam PF13468 Glyoxalase-like domain 4 170 1.9E-39 T 14-10-2018 IPR025870 Glyoxalase-like domain A4R43_14280 1a5614e5ff01e0bc22f794f14feeb78f 205 SUPERFAMILY SSF54593 2 139 1.18E-8 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_40910 b09a28fdc9d16753b3827eebdf1cbe2d 294 Pfam PF02219 Methylenetetrahydrofolate reductase 4 283 6.0E-93 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A4R43_40910 b09a28fdc9d16753b3827eebdf1cbe2d 294 Gene3D G3DSA:3.20.20.220 2 293 9.4E-95 T 14-10-2018 A4R43_40910 b09a28fdc9d16753b3827eebdf1cbe2d 294 SUPERFAMILY SSF51730 1 284 1.43E-87 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like A4R43_40910 b09a28fdc9d16753b3827eebdf1cbe2d 294 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 15 285 1.7E-95 T 14-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 Gene3D G3DSA:1.10.3730.40 184 337 6.5E-71 T 14-10-2018 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 5.0E-64 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 44.75 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 SUPERFAMILY SSF48179 185 330 5.1E-67 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 1.6E-73 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 SUPERFAMILY SSF51735 4 184 2.58E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 PIRSF PIRSF000116 4 211 5.1E-40 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 PIRSF PIRSF000116 204 334 5.1E-12 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 1.7E-130 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4R43_19990 0f40e2e8bdfa2cb56e9cf7c21319c822 337 Gene3D G3DSA:3.40.50.720 1 183 5.2E-76 T 14-10-2018 A4R43_13920 aec71c5756504a5e5ee9f3bac8f09737 223 Gene3D G3DSA:1.10.10.10 124 220 2.6E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13920 aec71c5756504a5e5ee9f3bac8f09737 223 Pfam PF00072 Response regulator receiver domain 3 113 7.4E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_13920 aec71c5756504a5e5ee9f3bac8f09737 223 Gene3D G3DSA:3.40.50.2300 1 121 4.9E-35 T 14-10-2018 A4R43_13920 aec71c5756504a5e5ee9f3bac8f09737 223 SMART SM00862 145 217 7.6E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_13920 aec71c5756504a5e5ee9f3bac8f09737 223 SUPERFAMILY SSF52172 2 171 3.27E-36 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_13920 aec71c5756504a5e5ee9f3bac8f09737 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 216 4.0E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_13920 aec71c5756504a5e5ee9f3bac8f09737 223 SMART SM00448 1 112 8.0E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_00810 19d3bf4ef78aa3ea0603c10839d3d592 92 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 57 4.7E-9 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4R43_00810 19d3bf4ef78aa3ea0603c10839d3d592 92 Gene3D G3DSA:3.40.1620.10 1 38 7.3E-6 T 14-10-2018 A4R43_00810 19d3bf4ef78aa3ea0603c10839d3d592 92 SUPERFAMILY SSF143120 1 45 7.46E-8 T 14-10-2018 IPR036165 YefM-like superfamily A4R43_00810 19d3bf4ef78aa3ea0603c10839d3d592 92 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 40 7.6E-6 T 14-10-2018 A4R43_09695 c2833c1c72c3d7fa1fb94522262b51e6 244 Pfam PF00376 MerR family regulatory protein 3 40 1.1E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_09695 c2833c1c72c3d7fa1fb94522262b51e6 244 SUPERFAMILY SSF46955 3 105 3.52E-24 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_09695 c2833c1c72c3d7fa1fb94522262b51e6 244 Gene3D G3DSA:1.10.1660.10 2 116 4.3E-24 T 14-10-2018 A4R43_09695 c2833c1c72c3d7fa1fb94522262b51e6 244 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 2.3E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_09695 c2833c1c72c3d7fa1fb94522262b51e6 244 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 2.3E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_09695 c2833c1c72c3d7fa1fb94522262b51e6 244 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 2.3E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_09695 c2833c1c72c3d7fa1fb94522262b51e6 244 SMART SM00422 2 71 1.0E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10605 b52a5e8f3e78d850c5ae2c2bab997343 598 Gene3D G3DSA:3.30.420.10 17 167 3.5E-12 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_10605 b52a5e8f3e78d850c5ae2c2bab997343 598 SUPERFAMILY SSF53098 21 165 1.23E-17 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_10605 b52a5e8f3e78d850c5ae2c2bab997343 598 PRINTS PR01217 Proline rich extensin signature 485 501 1.5E-9 T 14-10-2018 A4R43_10605 b52a5e8f3e78d850c5ae2c2bab997343 598 PRINTS PR01217 Proline rich extensin signature 440 452 1.5E-9 T 14-10-2018 A4R43_10605 b52a5e8f3e78d850c5ae2c2bab997343 598 PRINTS PR01217 Proline rich extensin signature 515 532 1.5E-9 T 14-10-2018 A4R43_10605 b52a5e8f3e78d850c5ae2c2bab997343 598 PRINTS PR01217 Proline rich extensin signature 455 476 1.5E-9 T 14-10-2018 A4R43_10605 b52a5e8f3e78d850c5ae2c2bab997343 598 SUPERFAMILY SSF158682 198 295 1.13E-11 T 14-10-2018 IPR029024 TerB-like A4R43_10605 b52a5e8f3e78d850c5ae2c2bab997343 598 Pfam PF05099 Tellurite resistance protein TerB 256 293 4.4E-5 T 14-10-2018 IPR007791 Co-chaperone DjlA, N-terminal A4R43_06345 0127012b440ae38c88ba3c05bb6748c3 308 SUPERFAMILY SSF161098 62 290 1.96E-46 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06345 0127012b440ae38c88ba3c05bb6748c3 308 Gene3D G3DSA:1.10.3720.10 58 306 3.4E-56 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06345 0127012b440ae38c88ba3c05bb6748c3 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 289 1.1E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_19565 a5f20811eb025f00e52b747e61b592ab 205 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 2 193 1.1E-38 T 14-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 A4R43_19565 a5f20811eb025f00e52b747e61b592ab 205 Gene3D G3DSA:3.90.550.10 1 168 5.2E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_19565 a5f20811eb025f00e52b747e61b592ab 205 Pfam PF01983 Guanylyl transferase CofC like 15 159 7.1E-6 T 14-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 A4R43_19565 a5f20811eb025f00e52b747e61b592ab 205 SUPERFAMILY SSF53448 5 195 7.5E-26 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_38270 46e0bf0330c0430b0d84a686f5598f9d 272 Gene3D G3DSA:3.40.800.10 6 262 2.0E-42 T 14-10-2018 A4R43_38270 46e0bf0330c0430b0d84a686f5598f9d 272 PRINTS PR00116 Arginase signature 157 175 2.0E-7 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_38270 46e0bf0330c0430b0d84a686f5598f9d 272 PRINTS PR00116 Arginase signature 107 134 2.0E-7 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_38270 46e0bf0330c0430b0d84a686f5598f9d 272 PRINTS PR00116 Arginase signature 83 98 2.0E-7 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_38270 46e0bf0330c0430b0d84a686f5598f9d 272 SUPERFAMILY SSF52768 59 245 2.34E-37 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily A4R43_38270 46e0bf0330c0430b0d84a686f5598f9d 272 Pfam PF00491 Arginase family 42 246 4.3E-26 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_36290 2a86722b9b6ec16ae3070141df90b99f 196 PIRSF PIRSF016661 13 195 8.6E-38 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A4R43_36290 2a86722b9b6ec16ae3070141df90b99f 196 Gene3D G3DSA:1.10.1760.20 19 190 9.8E-47 T 14-10-2018 A4R43_36290 2a86722b9b6ec16ae3070141df90b99f 196 Pfam PF02632 BioY family 48 186 1.3E-35 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A4R43_35715 3406ed4abd2ae62ec6e3d5a9047a504f 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 304 5.0E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_35715 3406ed4abd2ae62ec6e3d5a9047a504f 317 Gene3D G3DSA:1.10.3720.10 26 302 6.7E-55 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_35715 3406ed4abd2ae62ec6e3d5a9047a504f 317 SUPERFAMILY SSF161098 31 305 4.19E-49 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_17605 d41224a3e847960c500113a81a0dbf26 427 Gene3D G3DSA:3.90.1150.10 11 416 2.0E-156 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_17605 d41224a3e847960c500113a81a0dbf26 427 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 3 427 47.77 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A4R43_17605 d41224a3e847960c500113a81a0dbf26 427 Pfam PF00202 Aminotransferase class-III 26 422 1.2E-117 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_17605 d41224a3e847960c500113a81a0dbf26 427 Gene3D G3DSA:3.40.640.10 63 333 2.0E-156 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_17605 d41224a3e847960c500113a81a0dbf26 427 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 15 423 3.5E-165 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A4R43_17605 d41224a3e847960c500113a81a0dbf26 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_17605 d41224a3e847960c500113a81a0dbf26 427 SUPERFAMILY SSF53383 7 423 4.9E-119 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 SUPERFAMILY SSF55120 1 211 9.5E-64 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 277 14.289 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 Gene3D G3DSA:2.30.130.10 215 277 2.1E-25 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 11 166 1.3E-48 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 203 9.2E-61 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 167 208 7.2E-12 T 14-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 Gene3D G3DSA:3.30.2350.10 1 214 1.7E-79 T 14-10-2018 A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 SUPERFAMILY SSF88697 223 279 4.08E-12 T 14-10-2018 IPR015947 PUA-like superfamily A4R43_41130 21beb9b580cbade51ecbe851099b4856 280 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 223 277 5.6E-18 T 14-10-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_04365 4870b6c2ed5cf38141d8a62a960764da 290 SUPERFAMILY SSF50891 120 284 1.9E-32 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_04365 4870b6c2ed5cf38141d8a62a960764da 290 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 127 285 1.3E-23 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_04365 4870b6c2ed5cf38141d8a62a960764da 290 Gene3D G3DSA:2.40.100.10 115 290 1.4E-40 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_29300 56cae501065fe4ece4fb602a64e48f4f 422 Gene3D G3DSA:1.10.260.40 9 69 1.6E-12 T 14-10-2018 A4R43_29300 56cae501065fe4ece4fb602a64e48f4f 422 SUPERFAMILY SSF48452 232 406 9.63E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_29300 56cae501065fe4ece4fb602a64e48f4f 422 Pfam PF13560 Helix-turn-helix domain 9 66 4.3E-9 T 14-10-2018 A4R43_29300 56cae501065fe4ece4fb602a64e48f4f 422 SMART SM00530 8 63 5.8E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_29300 56cae501065fe4ece4fb602a64e48f4f 422 SUPERFAMILY SSF47413 9 63 2.96E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 SMART SM00898 2 109 2.4E-16 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 SUPERFAMILY SSF46946 122 191 6.62E-15 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 Gene3D G3DSA:3.20.190.10 2 123 5.3E-25 T 14-10-2018 IPR035937 MutM-like, N-terminal A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 123 199 4.3E-8 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 SUPERFAMILY SSF57716 220 260 4.56E-7 T 14-10-2018 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 Gene3D G3DSA:1.10.8.50 124 261 3.0E-27 T 14-10-2018 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 8 96 6.8E-9 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 SMART SM01232 123 213 2.4E-19 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 ProSitePatterns PS01242 Zinc finger FPG-type signature. 232 260 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A4R43_41345 d350832a691a39d42e5582e7e5ba44ec 267 SUPERFAMILY SSF81624 2 124 7.59E-25 T 14-10-2018 IPR035937 MutM-like, N-terminal A4R43_09740 55abc52b81eebd561a8530fbd27919af 257 Gene3D G3DSA:3.40.50.150 7 228 1.2E-35 T 14-10-2018 A4R43_09740 55abc52b81eebd561a8530fbd27919af 257 Pfam PF08241 Methyltransferase domain 40 126 8.2E-17 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_09740 55abc52b81eebd561a8530fbd27919af 257 SUPERFAMILY SSF53335 6 208 1.4E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_04465 f403558f84f57b857b1cee39198c9236 589 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 579 8.5E-210 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 1.5E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 1.5E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 517 531 1.5E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 473 489 1.5E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 SUPERFAMILY SSF55261 289 411 4.25E-34 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 556 2.9E-101 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 583 32.023 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 5.9E-16 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 Pfam PF02938 GAD domain 313 395 3.2E-13 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 SUPERFAMILY SSF55681 111 581 3.19E-100 T 14-10-2018 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 Gene3D G3DSA:3.30.930.10 139 574 5.2E-180 T 14-10-2018 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 SUPERFAMILY SSF50249 2 104 7.43E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_04465 f403558f84f57b857b1cee39198c9236 589 Gene3D G3DSA:2.40.50.140 1 106 6.4E-34 T 14-10-2018 A4R43_04465 f403558f84f57b857b1cee39198c9236 589 Gene3D G3DSA:3.30.1360.30 272 413 5.2E-180 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A4R43_30200 87582bc8868e6bf489885ee7a8bea993 228 SUPERFAMILY SSF46689 13 90 1.69E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_30200 87582bc8868e6bf489885ee7a8bea993 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 2.5E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_30200 87582bc8868e6bf489885ee7a8bea993 228 Gene3D G3DSA:1.10.357.10 66 204 2.9E-9 T 14-10-2018 A4R43_30200 87582bc8868e6bf489885ee7a8bea993 228 Gene3D G3DSA:1.10.10.60 3 65 6.1E-14 T 14-10-2018 A4R43_30200 87582bc8868e6bf489885ee7a8bea993 228 SUPERFAMILY SSF48498 92 196 7.11E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_00545 5cfc2c90a5e4cb6b2d4a9fda52204288 389 Gene3D G3DSA:1.10.260.160 230 321 1.7E-74 T 14-10-2018 A4R43_00545 5cfc2c90a5e4cb6b2d4a9fda52204288 389 SUPERFAMILY SSF53474 61 385 1.02E-15 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00545 5cfc2c90a5e4cb6b2d4a9fda52204288 389 PIRSF PIRSF029171 1 388 1.1E-67 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_00545 5cfc2c90a5e4cb6b2d4a9fda52204288 389 Gene3D G3DSA:3.40.50.1820 58 352 1.7E-74 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00545 5cfc2c90a5e4cb6b2d4a9fda52204288 389 Pfam PF03583 Secretory lipase 129 196 8.5E-5 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_15785 a318d4ff0e46d13d78ede7373c76f428 381 Pfam PF03631 Virulence factor BrkB 42 300 1.5E-39 T 14-10-2018 IPR017039 Virulence factor BrkB A4R43_15785 a318d4ff0e46d13d78ede7373c76f428 381 PIRSF PIRSF035875 14 321 7.0E-54 T 14-10-2018 IPR017039 Virulence factor BrkB A4R43_01660 5944087f337b1a72c008c20696e7f7a3 67 SUPERFAMILY SSF54862 5 64 6.81E-11 T 14-10-2018 A4R43_01660 5944087f337b1a72c008c20696e7f7a3 67 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 2.7E-6 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_01660 5944087f337b1a72c008c20696e7f7a3 67 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.7E-6 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_01660 5944087f337b1a72c008c20696e7f7a3 67 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.7E-6 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_01660 5944087f337b1a72c008c20696e7f7a3 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 63 1.3E-13 T 14-10-2018 A4R43_01660 5944087f337b1a72c008c20696e7f7a3 67 Gene3D G3DSA:3.30.70.20 2 66 4.1E-17 T 14-10-2018 A4R43_05005 a9f62544ad2325a896aa002815155d10 324 SUPERFAMILY SSF50129 9 141 4.87E-38 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_05005 a9f62544ad2325a896aa002815155d10 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A4R43_05005 a9f62544ad2325a896aa002815155d10 324 Gene3D G3DSA:3.40.50.720 123 268 2.6E-115 T 14-10-2018 A4R43_05005 a9f62544ad2325a896aa002815155d10 324 SUPERFAMILY SSF51735 112 262 4.17E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05005 a9f62544ad2325a896aa002815155d10 324 Gene3D G3DSA:3.90.180.10 11 320 2.6E-115 T 14-10-2018 A4R43_05005 a9f62544ad2325a896aa002815155d10 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 3.1E-10 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_05005 a9f62544ad2325a896aa002815155d10 324 SMART SM00829 12 322 1.2E-23 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_05005 a9f62544ad2325a896aa002815155d10 324 Pfam PF00107 Zinc-binding dehydrogenase 151 252 2.5E-28 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 Pfam PF00582 Universal stress protein family 157 293 1.4E-27 T 14-10-2018 IPR006016 UspA A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 Pfam PF00582 Universal stress protein family 7 146 1.5E-22 T 14-10-2018 IPR006016 UspA A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 PRINTS PR01438 Universal stress protein signature 253 265 8.4E-17 T 14-10-2018 IPR006015 Universal stress protein A A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 PRINTS PR01438 Universal stress protein signature 271 293 8.4E-17 T 14-10-2018 IPR006015 Universal stress protein A A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 PRINTS PR01438 Universal stress protein signature 154 172 8.4E-17 T 14-10-2018 IPR006015 Universal stress protein A A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 Gene3D G3DSA:3.40.50.620 151 299 8.8E-43 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 Gene3D G3DSA:3.40.50.620 3 150 3.8E-28 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 SUPERFAMILY SSF52402 156 294 2.26E-32 T 14-10-2018 A4R43_01950 dda51dfec7ab173c1738d4cc59884ffa 300 SUPERFAMILY SSF52402 7 148 9.21E-24 T 14-10-2018 A4R43_13105 f5a13a3ead351964b29ed75f8f1d3e43 319 SUPERFAMILY SSF56281 14 310 2.03E-49 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_13105 f5a13a3ead351964b29ed75f8f1d3e43 319 Gene3D G3DSA:3.60.15.10 12 240 1.1E-34 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_13105 f5a13a3ead351964b29ed75f8f1d3e43 319 SMART SM00849 33 222 6.5E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_13105 f5a13a3ead351964b29ed75f8f1d3e43 319 Pfam PF00753 Metallo-beta-lactamase superfamily 33 213 2.1E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_19370 d1b3788c92213b9d1daa36328f453f40 181 Gene3D G3DSA:2.60.130.10 1 181 1.0E-68 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4R43_19370 d1b3788c92213b9d1daa36328f453f40 181 Pfam PF00775 Dioxygenase 32 150 4.5E-17 T 14-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 A4R43_19370 d1b3788c92213b9d1daa36328f453f40 181 SUPERFAMILY SSF49482 2 180 3.4E-53 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4R43_19370 d1b3788c92213b9d1daa36328f453f40 181 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 3 181 6.3E-68 T 14-10-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 SUPERFAMILY SSF52821 4 140 7.2E-36 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 Gene3D G3DSA:3.40.250.10 1 141 1.7E-42 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 Gene3D G3DSA:3.40.250.10 142 277 1.6E-44 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 Pfam PF00581 Rhodanese-like domain 10 118 2.4E-15 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 Pfam PF00581 Rhodanese-like domain 149 266 3.0E-19 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 SUPERFAMILY SSF52821 149 276 1.83E-36 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 SMART SM00450 8 122 5.4E-20 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_32065 20c846f2e8b8e51f595d769496d31c52 278 SMART SM00450 144 271 4.6E-22 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_32880 ab14115dfc6c81f9a6b9c89d560a0d0e 508 Pfam PF00174 Oxidoreductase molybdopterin binding domain 233 380 9.7E-36 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4R43_32880 ab14115dfc6c81f9a6b9c89d560a0d0e 508 SUPERFAMILY SSF81296 397 504 6.79E-22 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_32880 ab14115dfc6c81f9a6b9c89d560a0d0e 508 Gene3D G3DSA:2.60.40.650 397 508 3.1E-23 T 14-10-2018 A4R43_32880 ab14115dfc6c81f9a6b9c89d560a0d0e 508 Gene3D G3DSA:3.90.420.10 195 396 2.3E-48 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A4R43_32880 ab14115dfc6c81f9a6b9c89d560a0d0e 508 SUPERFAMILY SSF56524 216 404 1.83E-53 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A4R43_25930 4132085f051660fe142575712c524677 144 Pfam PF01967 MoaC family 1 134 1.6E-49 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_25930 4132085f051660fe142575712c524677 144 SUPERFAMILY SSF55040 1 139 5.75E-52 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_25930 4132085f051660fe142575712c524677 144 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 1 135 1.7E-55 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_25930 4132085f051660fe142575712c524677 144 Gene3D G3DSA:3.30.70.640 1 144 1.0E-58 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4R43_28400 82200def6b0bb384ce772f4bcaf47526 531 SUPERFAMILY SSF56300 92 447 9.1E-11 T 14-10-2018 A4R43_28400 82200def6b0bb384ce772f4bcaf47526 531 Pfam PF09423 PhoD-like phosphatase 121 431 2.8E-11 T 14-10-2018 IPR018946 Alkaline phosphatase D-related A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 PRINTS PR00412 Epoxide hydrolase signature 63 78 2.1E-19 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 PRINTS PR00412 Epoxide hydrolase signature 43 61 2.1E-19 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 PRINTS PR00412 Epoxide hydrolase signature 107 120 2.1E-19 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 PRINTS PR00412 Epoxide hydrolase signature 287 309 2.1E-19 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 SUPERFAMILY SSF53474 14 312 6.29E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 Gene3D G3DSA:3.40.50.1820 16 311 1.3E-68 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 Pfam PF12697 Alpha/beta hydrolase family 39 302 6.1E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 2.4E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_27140 71edc50074d647987d7dcd4749c0a8cd 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 2.4E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_11440 e619c374882892a692cd740001de35d3 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 226 1.7E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_11440 e619c374882892a692cd740001de35d3 232 SMART SM00862 153 227 3.0E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_11440 e619c374882892a692cd740001de35d3 232 Gene3D G3DSA:3.40.50.2300 1 130 2.6E-34 T 14-10-2018 A4R43_11440 e619c374882892a692cd740001de35d3 232 SMART SM00448 7 118 3.5E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_11440 e619c374882892a692cd740001de35d3 232 Gene3D G3DSA:1.10.10.10 131 232 7.4E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11440 e619c374882892a692cd740001de35d3 232 SUPERFAMILY SSF52172 5 175 4.69E-38 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_11440 e619c374882892a692cd740001de35d3 232 Pfam PF00072 Response regulator receiver domain 10 118 8.3E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 Gene3D G3DSA:3.40.50.720 1 250 1.5E-81 T 14-10-2018 A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 187 0.002 T 14-10-2018 A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 248 5.0E-66 T 14-10-2018 A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 SUPERFAMILY SSF51735 3 249 8.11E-81 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 9.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 9.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 9.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 9.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19810 ee293f3315ed4e04fe68ce4884fc3563 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23645 1b379a62338d60e059563d1089a2222d 626 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 273 430 2.0E-11 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 Gene3D G3DSA:1.20.140.10 273 439 1.8E-48 T 14-10-2018 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 23 125 3.2E-5 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 Pfam PF01756 Acyl-CoA oxidase 487 623 3.8E-21 T 14-10-2018 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 239 3.9E-16 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 PIRSF PIRSF000168 2 626 3.4E-165 T 14-10-2018 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0071949 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858|Reactome: R-HSA-9033241 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 SUPERFAMILY SSF47203 269 450 1.54E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 SUPERFAMILY SSF56645 14 254 1.14E-52 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 Gene3D G3DSA:2.40.110.10 132 262 1.9E-48 T 14-10-2018 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 Gene3D G3DSA:1.10.540.10 20 129 2.2E-5 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 Gene3D G3DSA:1.20.140.10 485 613 7.5E-24 T 14-10-2018 A4R43_23645 1b379a62338d60e059563d1089a2222d 626 SUPERFAMILY SSF47203 480 623 5.12E-37 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_30005 4767b458d34da1d1fda84baf012783f3 196 Gene3D G3DSA:1.10.10.60 2 62 1.1E-17 T 14-10-2018 A4R43_30005 4767b458d34da1d1fda84baf012783f3 196 SUPERFAMILY SSF48498 87 190 9.53E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_30005 4767b458d34da1d1fda84baf012783f3 196 SUPERFAMILY SSF46689 8 91 6.16E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_30005 4767b458d34da1d1fda84baf012783f3 196 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_30005 4767b458d34da1d1fda84baf012783f3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_30005 4767b458d34da1d1fda84baf012783f3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_30005 4767b458d34da1d1fda84baf012783f3 196 Gene3D G3DSA:1.10.357.10 63 195 8.3E-33 T 14-10-2018 A4R43_30005 4767b458d34da1d1fda84baf012783f3 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 8.2E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03200 8b80222c3f1640c9f1bb578fbac4bd32 472 Pfam PF07690 Major Facilitator Superfamily 21 417 7.8E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_03200 8b80222c3f1640c9f1bb578fbac4bd32 472 Gene3D G3DSA:1.20.1720.10 17 227 1.0E-44 T 14-10-2018 A4R43_03200 8b80222c3f1640c9f1bb578fbac4bd32 472 SUPERFAMILY SSF103473 9 461 2.62E-53 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_03200 8b80222c3f1640c9f1bb578fbac4bd32 472 Gene3D G3DSA:1.20.1250.20 274 466 1.1E-12 T 14-10-2018 A4R43_07740 4c5dc02086d06eb0c45e79c44cf933cc 165 SUPERFAMILY SSF109854 9 158 3.05E-34 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_07740 4c5dc02086d06eb0c45e79c44cf933cc 165 Gene3D G3DSA:1.20.120.450 2 163 2.1E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_07740 4c5dc02086d06eb0c45e79c44cf933cc 165 Pfam PF04978 Protein of unknown function (DUF664) 15 159 1.5E-40 T 14-10-2018 IPR007061 Protein of unknown function DUF664 A4R43_00990 e172f8b698a467c23d8789a0a99a7665 458 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 125 164 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4R43_00990 e172f8b698a467c23d8789a0a99a7665 458 Gene3D G3DSA:3.30.70.360 204 367 1.0E-88 T 14-10-2018 A4R43_00990 e172f8b698a467c23d8789a0a99a7665 458 Pfam PF01546 Peptidase family M20/M25/M40 89 443 3.6E-23 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_00990 e172f8b698a467c23d8789a0a99a7665 458 Gene3D G3DSA:3.40.630.10 49 434 1.0E-88 T 14-10-2018 A4R43_00990 e172f8b698a467c23d8789a0a99a7665 458 Pfam PF07687 Peptidase dimerisation domain 202 354 3.8E-7 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_00990 e172f8b698a467c23d8789a0a99a7665 458 SUPERFAMILY SSF53187 16 451 8.0E-48 T 14-10-2018 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 SUPERFAMILY SSF47203 227 381 2.26E-51 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 205 1.2E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 Gene3D G3DSA:1.10.540.10 1 123 5.0E-26 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 121 7.1E-21 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 Gene3D G3DSA:2.40.110.10 124 234 4.2E-36 T 14-10-2018 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 378 1.9E-44 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 SUPERFAMILY SSF56645 1 241 1.31E-67 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_25420 b39dbd33d44c255e74615f461f5b366c 389 Gene3D G3DSA:1.20.140.10 235 385 9.4E-50 T 14-10-2018 A4R43_01740 ada7a860976af46025358924e4287192 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_01740 ada7a860976af46025358924e4287192 499 Gene3D G3DSA:3.40.605.10 26 460 1.5E-150 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_01740 ada7a860976af46025358924e4287192 499 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 483 1.1E-210 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 A4R43_01740 ada7a860976af46025358924e4287192 499 SUPERFAMILY SSF53720 7 483 3.8E-147 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_01740 ada7a860976af46025358924e4287192 499 Pfam PF00171 Aldehyde dehydrogenase family 20 479 9.7E-143 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_01740 ada7a860976af46025358924e4287192 499 Gene3D G3DSA:3.40.309.10 252 452 1.5E-150 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_40930 6683a100da81aaf2460f9c53feea4d74 237 SUPERFAMILY SSF110399 4 236 3.66E-48 T 14-10-2018 A4R43_40930 6683a100da81aaf2460f9c53feea4d74 237 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 236 2.2E-58 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A4R43_40930 6683a100da81aaf2460f9c53feea4d74 237 Gene3D G3DSA:3.20.20.70 1 237 3.1E-74 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_39575 4e0d90cbf0b0f3ec359680d1a5f962da 134 Pfam PF14534 Domain of unknown function (DUF4440) 12 121 3.9E-12 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 A4R43_39575 4e0d90cbf0b0f3ec359680d1a5f962da 134 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 5 129 2.3E-27 T 14-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 A4R43_39575 4e0d90cbf0b0f3ec359680d1a5f962da 134 SUPERFAMILY SSF54427 5 131 2.06E-33 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_39575 4e0d90cbf0b0f3ec359680d1a5f962da 134 Gene3D G3DSA:3.10.450.50 3 133 4.2E-43 T 14-10-2018 A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 Gene3D G3DSA:3.40.50.720 1 189 8.9E-57 T 14-10-2018 A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 Gene3D G3DSA:1.10.1040.50 190 479 3.0E-85 T 14-10-2018 A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 Gene3D G3DSA:3.30.750.190 290 396 3.0E-85 T 14-10-2018 A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3 185 1.4E-49 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 SUPERFAMILY SSF51735 2 186 1.11E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 SUPERFAMILY SSF48179 186 291 2.72E-23 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 283 2.2E-21 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 401 482 1.8E-14 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_21325 1a5ea2f0ddd6a46a821d7f5d8069613e 497 SUPERFAMILY SSF48179 398 482 1.36E-15 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_30095 5751bee02dbb75d1d8bf93c64f5f47fc 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 1.1E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30095 5751bee02dbb75d1d8bf93c64f5f47fc 222 SMART SM00448 6 121 2.1E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30095 5751bee02dbb75d1d8bf93c64f5f47fc 222 Pfam PF00072 Response regulator receiver domain 8 119 7.0E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30095 5751bee02dbb75d1d8bf93c64f5f47fc 222 SUPERFAMILY SSF52172 5 184 2.7E-23 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_30095 5751bee02dbb75d1d8bf93c64f5f47fc 222 SMART SM00421 151 208 9.5E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30095 5751bee02dbb75d1d8bf93c64f5f47fc 222 Gene3D G3DSA:3.40.50.12740 7 214 1.9E-43 T 14-10-2018 A4R43_14880 9feaa7352e20b903def7ef4377020c5a 321 Pfam PF00005 ABC transporter 83 243 9.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14880 9feaa7352e20b903def7ef4377020c5a 321 SMART SM00382 92 292 1.5E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14880 9feaa7352e20b903def7ef4377020c5a 321 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 292 314 8.0E-12 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4R43_14880 9feaa7352e20b903def7ef4377020c5a 321 SUPERFAMILY SSF52540 66 314 5.52E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14880 9feaa7352e20b903def7ef4377020c5a 321 Gene3D G3DSA:3.40.50.300 63 316 7.2E-62 T 14-10-2018 A4R43_20115 7b1769e18fc3e28c6b8604560bf75521 362 Gene3D G3DSA:2.40.30.10 279 361 3.6E-10 T 14-10-2018 A4R43_20115 7b1769e18fc3e28c6b8604560bf75521 362 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 359 36.579 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A4R43_20115 7b1769e18fc3e28c6b8604560bf75521 362 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 358 4.6E-89 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A4R43_20115 7b1769e18fc3e28c6b8604560bf75521 362 SUPERFAMILY SSF52402 1 243 2.14E-46 T 14-10-2018 A4R43_20115 7b1769e18fc3e28c6b8604560bf75521 362 Pfam PF03054 tRNA methyl transferase 1 358 7.5E-115 T 14-10-2018 A4R43_20115 7b1769e18fc3e28c6b8604560bf75521 362 Gene3D G3DSA:3.40.50.620 1 210 1.7E-73 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_20115 7b1769e18fc3e28c6b8604560bf75521 362 Gene3D G3DSA:2.30.30.280 212 277 1.4E-11 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A4R43_15470 9919d3bcc017e7d8790293dd160e95f9 150 Pfam PF04542 Sigma-70 region 2 13 73 5.8E-6 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_15470 9919d3bcc017e7d8790293dd160e95f9 150 Pfam PF08281 Sigma-70, region 4 96 140 1.4E-6 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_15470 9919d3bcc017e7d8790293dd160e95f9 150 SUPERFAMILY SSF88946 7 71 1.33E-6 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_15470 9919d3bcc017e7d8790293dd160e95f9 150 SUPERFAMILY SSF88659 87 143 7.66E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_15470 9919d3bcc017e7d8790293dd160e95f9 150 Gene3D G3DSA:1.10.10.10 67 146 2.1E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09585 0643e214ab5995be3316618feecf2576 217 SUPERFAMILY SSF56784 7 216 3.34E-33 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_09585 0643e214ab5995be3316618feecf2576 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 4.7E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_09585 0643e214ab5995be3316618feecf2576 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 171 4.7E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_09585 0643e214ab5995be3316618feecf2576 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 4.7E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_09585 0643e214ab5995be3316618feecf2576 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 178 191 4.7E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_09585 0643e214ab5995be3316618feecf2576 217 Gene3D G3DSA:1.10.150.240 32 91 6.1E-54 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_09585 0643e214ab5995be3316618feecf2576 217 Gene3D G3DSA:3.40.50.1000 7 201 6.1E-54 T 14-10-2018 IPR023214 HAD superfamily A4R43_09585 0643e214ab5995be3316618feecf2576 217 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 7 195 2.0E-50 T 14-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 A4R43_09585 0643e214ab5995be3316618feecf2576 217 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 9 181 4.1E-32 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_09585 0643e214ab5995be3316618feecf2576 217 Pfam PF00702 haloacid dehalogenase-like hydrolase 7 183 1.8E-6 T 14-10-2018 A4R43_36055 4f81761f7551eb95bf8695c9d1dfea56 187 PIRSF PIRSF026640 1 187 4.0E-47 T 14-10-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_36055 4f81761f7551eb95bf8695c9d1dfea56 187 Gene3D G3DSA:1.20.1250.110 20 186 4.4E-56 T 14-10-2018 A4R43_36055 4f81761f7551eb95bf8695c9d1dfea56 187 Pfam PF01817 Chorismate mutase type II 33 99 2.4E-9 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_36055 4f81761f7551eb95bf8695c9d1dfea56 187 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 29 138 7.9E-29 T 14-10-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_36055 4f81761f7551eb95bf8695c9d1dfea56 187 SMART SM00830 32 102 5.8E-10 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_36055 4f81761f7551eb95bf8695c9d1dfea56 187 SUPERFAMILY SSF48600 31 185 8.4E-34 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4R43_17860 9964fef6a475229273b1d344a04c0517 245 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 77 92 - T 14-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A4R43_17860 9964fef6a475229273b1d344a04c0517 245 Pfam PF03099 Biotin/lipoate A/B protein ligase family 69 170 1.5E-7 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A4R43_17860 9964fef6a475229273b1d344a04c0517 245 PIRSF PIRSF016262 8 224 3.3E-59 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_17860 9964fef6a475229273b1d344a04c0517 245 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 32 200 7.3E-38 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_17860 9964fef6a475229273b1d344a04c0517 245 SUPERFAMILY SSF55681 12 216 3.07E-64 T 14-10-2018 A4R43_17860 9964fef6a475229273b1d344a04c0517 245 Hamap MF_00013 Octanoyltransferase [lipB]. 11 222 33.52 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4R43_17860 9964fef6a475229273b1d344a04c0517 245 Gene3D G3DSA:3.30.930.10 5 216 3.2E-78 T 14-10-2018 A4R43_17860 9964fef6a475229273b1d344a04c0517 245 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 81 133 1.0E-17 T 14-10-2018 A4R43_16290 a2dde966214d231581d50e8051087810 301 Pfam PF13622 Thioesterase-like superfamily 45 297 4.5E-63 T 14-10-2018 A4R43_16290 a2dde966214d231581d50e8051087810 301 SUPERFAMILY SSF54637 135 299 5.82E-49 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_16290 a2dde966214d231581d50e8051087810 301 SUPERFAMILY SSF54637 23 133 2.13E-42 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_16290 a2dde966214d231581d50e8051087810 301 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 31 299 3.3E-91 T 14-10-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 A4R43_16290 a2dde966214d231581d50e8051087810 301 Gene3D G3DSA:3.10.129.90 21 300 1.5E-106 T 14-10-2018 A4R43_40965 82b82ddef7aeb867c8bebd3f18bd7957 190 SUPERFAMILY SSF46689 2 65 5.99E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_40965 82b82ddef7aeb867c8bebd3f18bd7957 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 7.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40965 82b82ddef7aeb867c8bebd3f18bd7957 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 7.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40965 82b82ddef7aeb867c8bebd3f18bd7957 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 49 3.2E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40965 82b82ddef7aeb867c8bebd3f18bd7957 190 Gene3D G3DSA:1.10.357.10 1 124 3.4E-24 T 14-10-2018 A4R43_34640 7e1020df1994448f94e48501eb8cff40 252 SUPERFAMILY SSF50494 21 249 3.5E-46 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_34640 7e1020df1994448f94e48501eb8cff40 252 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 111 125 4.0E-12 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_34640 7e1020df1994448f94e48501eb8cff40 252 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 195 207 4.0E-12 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_34640 7e1020df1994448f94e48501eb8cff40 252 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 68 83 4.0E-12 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_34640 7e1020df1994448f94e48501eb8cff40 252 Gene3D G3DSA:2.40.10.10 42 113 7.4E-14 T 14-10-2018 A4R43_34640 7e1020df1994448f94e48501eb8cff40 252 SMART SM00020 41 246 8.3E-39 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_34640 7e1020df1994448f94e48501eb8cff40 252 Gene3D G3DSA:2.40.10.10 114 250 4.5E-24 T 14-10-2018 A4R43_34640 7e1020df1994448f94e48501eb8cff40 252 Pfam PF00089 Trypsin 45 246 2.7E-35 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_36865 af933ae6bd4c0d94a502f0cd1b46bb4a 469 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 2 236 9.9E-33 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4R43_36865 af933ae6bd4c0d94a502f0cd1b46bb4a 469 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 298 419 6.5E-17 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4R43_36865 af933ae6bd4c0d94a502f0cd1b46bb4a 469 PIRSF PIRSF000538 1 466 1.5E-69 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_36865 af933ae6bd4c0d94a502f0cd1b46bb4a 469 SUPERFAMILY SSF53067 241 459 6.69E-27 T 14-10-2018 A4R43_36865 af933ae6bd4c0d94a502f0cd1b46bb4a 469 Gene3D G3DSA:3.30.420.40 234 465 4.5E-40 T 14-10-2018 A4R43_36865 af933ae6bd4c0d94a502f0cd1b46bb4a 469 Gene3D G3DSA:3.30.420.40 1 233 1.5E-55 T 14-10-2018 A4R43_36865 af933ae6bd4c0d94a502f0cd1b46bb4a 469 SUPERFAMILY SSF53067 2 234 6.47E-43 T 14-10-2018 A4R43_40605 bd8fa373349be5652161f8f829634aee 392 Gene3D G3DSA:1.20.1250.20 12 385 7.8E-49 T 14-10-2018 A4R43_40605 bd8fa373349be5652161f8f829634aee 392 SUPERFAMILY SSF103473 15 391 6.02E-55 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_40605 bd8fa373349be5652161f8f829634aee 392 Pfam PF07690 Major Facilitator Superfamily 22 352 2.0E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_40605 bd8fa373349be5652161f8f829634aee 392 PRINTS PR01035 Tetracycline resistance protein signature 54 73 7.4E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_40605 bd8fa373349be5652161f8f829634aee 392 PRINTS PR01035 Tetracycline resistance protein signature 336 359 7.4E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_40605 bd8fa373349be5652161f8f829634aee 392 PRINTS PR01035 Tetracycline resistance protein signature 143 165 7.4E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_40605 bd8fa373349be5652161f8f829634aee 392 PRINTS PR01035 Tetracycline resistance protein signature 25 41 7.4E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_04040 4c9f8ffee5c6cad38933b2c8195d0cd1 314 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A4R43_04040 4c9f8ffee5c6cad38933b2c8195d0cd1 314 PRINTS PR00069 Aldo-keto reductase signature 28 52 2.8E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_04040 4c9f8ffee5c6cad38933b2c8195d0cd1 314 PRINTS PR00069 Aldo-keto reductase signature 92 110 2.8E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_04040 4c9f8ffee5c6cad38933b2c8195d0cd1 314 PRINTS PR00069 Aldo-keto reductase signature 123 140 2.8E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_04040 4c9f8ffee5c6cad38933b2c8195d0cd1 314 SUPERFAMILY SSF51430 3 310 4.45E-81 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_04040 4c9f8ffee5c6cad38933b2c8195d0cd1 314 Gene3D G3DSA:3.20.20.100 1 314 1.9E-99 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_04040 4c9f8ffee5c6cad38933b2c8195d0cd1 314 Pfam PF00248 Aldo/keto reductase family 4 301 4.6E-65 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_29090 9fdd53bb3ad4babf5f5cb69dda37d3c7 429 Gene3D G3DSA:3.30.2320.60 2 128 8.1E-47 T 14-10-2018 A4R43_29090 9fdd53bb3ad4babf5f5cb69dda37d3c7 429 Pfam PF00498 FHA domain 357 419 2.5E-17 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4R43_29090 9fdd53bb3ad4babf5f5cb69dda37d3c7 429 SMART SM00240 355 405 3.3E-13 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4R43_29090 9fdd53bb3ad4babf5f5cb69dda37d3c7 429 Pfam PF12401 Protein of unknown function (DUF2662) 5 118 1.9E-39 T 14-10-2018 IPR022128 Domain of unknown function DUF3662 A4R43_29090 9fdd53bb3ad4babf5f5cb69dda37d3c7 429 SUPERFAMILY SSF49879 323 426 2.87E-29 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 A4R43_29090 9fdd53bb3ad4babf5f5cb69dda37d3c7 429 Gene3D G3DSA:2.60.200.20 315 428 6.4E-29 T 14-10-2018 A4R43_24035 3220a5dfcdb077e3c6957fd3cf857a39 206 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 176 8.8E-50 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4R43_24035 3220a5dfcdb077e3c6957fd3cf857a39 206 Pfam PF01386 Ribosomal L25p family 6 92 1.2E-24 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4R43_24035 3220a5dfcdb077e3c6957fd3cf857a39 206 SUPERFAMILY SSF50715 10 177 2.96E-48 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_24035 3220a5dfcdb077e3c6957fd3cf857a39 206 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 11 91 5.0E-20 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4R43_24035 3220a5dfcdb077e3c6957fd3cf857a39 206 Gene3D G3DSA:2.170.120.20 96 179 3.8E-16 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal A4R43_24035 3220a5dfcdb077e3c6957fd3cf857a39 206 Gene3D G3DSA:2.40.240.10 2 95 6.8E-26 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_24035 3220a5dfcdb077e3c6957fd3cf857a39 206 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 178 6.8E-19 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain A4R43_24035 3220a5dfcdb077e3c6957fd3cf857a39 206 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 180 25.434 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4R43_23345 1e1571b426130a1034436191f6ae99d3 600 Gene3D G3DSA:3.10.105.10 348 569 1.7E-42 T 14-10-2018 A4R43_23345 1e1571b426130a1034436191f6ae99d3 600 Gene3D G3DSA:3.40.190.10 35 346 5.5E-41 T 14-10-2018 A4R43_23345 1e1571b426130a1034436191f6ae99d3 600 SUPERFAMILY SSF53850 60 577 8.65E-78 T 14-10-2018 A4R43_23345 1e1571b426130a1034436191f6ae99d3 600 PIRSF PIRSF002741 58 587 8.1E-51 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_23345 1e1571b426130a1034436191f6ae99d3 600 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 114 510 1.5E-54 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_05985 a8736e78b282665414d977dd91036165 367 Gene3D G3DSA:3.90.1510.10 43 269 7.4E-124 T 14-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 A4R43_05985 a8736e78b282665414d977dd91036165 367 Pfam PF02595 Glycerate kinase family 4 361 7.2E-128 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_05985 a8736e78b282665414d977dd91036165 367 Gene3D G3DSA:3.40.50.10350 4 353 7.4E-124 T 14-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold A4R43_05985 a8736e78b282665414d977dd91036165 367 PIRSF PIRSF006078 2 367 3.2E-118 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_05985 a8736e78b282665414d977dd91036165 367 SUPERFAMILY SSF110738 3 360 2.35E-115 T 14-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 A4R43_05985 a8736e78b282665414d977dd91036165 367 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 4 361 5.1E-112 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_00905 74243da2cbdf46bcbcafa91f837a6721 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 8.4E-41 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_00905 74243da2cbdf46bcbcafa91f837a6721 327 SUPERFAMILY SSF53850 114 286 1.76E-11 T 14-10-2018 A4R43_00905 74243da2cbdf46bcbcafa91f837a6721 327 PIRSF PIRSF017082 1 326 1.7E-67 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_00905 74243da2cbdf46bcbcafa91f837a6721 327 Gene3D G3DSA:3.40.190.10 127 253 1.9E-75 T 14-10-2018 A4R43_00905 74243da2cbdf46bcbcafa91f837a6721 327 Gene3D G3DSA:3.40.190.150 31 318 1.9E-75 T 14-10-2018 A4R43_34205 9708bba12f29014e953412042867cc94 374 SMART SM01005 243 371 7.7E-61 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 Pfam PF01168 Alanine racemase, N-terminal domain 13 233 5.1E-66 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 Gene3D G3DSA:3.20.20.10 15 228 5.2E-127 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_34205 9708bba12f29014e953412042867cc94 374 Pfam PF00842 Alanine racemase, C-terminal domain 243 370 4.3E-42 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 Hamap MF_01201 Alanine racemase. 6 371 32.436 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 69 87 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 352 365 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 130 142 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 164 175 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 297 314 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 33 49 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 259 274 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 206 233 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 PRINTS PR00992 Alanine racemase signature 276 291 1.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 TIGRFAM TIGR00492 alr: alanine racemase 9 370 1.9E-91 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_34205 9708bba12f29014e953412042867cc94 374 SUPERFAMILY SSF50621 236 372 9.77E-46 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4R43_34205 9708bba12f29014e953412042867cc94 374 SUPERFAMILY SSF51419 13 244 6.25E-62 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_34205 9708bba12f29014e953412042867cc94 374 Gene3D G3DSA:2.40.37.10 13 370 5.2E-127 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4R43_35210 bea34918f4904423be588e2571dd28a7 319 Pfam PF00877 NlpC/P60 family 212 308 2.2E-22 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_35210 bea34918f4904423be588e2571dd28a7 319 Gene3D G3DSA:3.90.1720.10 169 312 3.7E-36 T 14-10-2018 A4R43_35210 bea34918f4904423be588e2571dd28a7 319 SUPERFAMILY SSF54001 201 307 3.29E-30 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_23120 731aba8e5b6b8cfee0e36bcb77b86a22 308 Gene3D G3DSA:2.60.200.40 136 298 1.2E-16 T 14-10-2018 A4R43_23120 731aba8e5b6b8cfee0e36bcb77b86a22 308 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 122 1.3E-26 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4R43_23120 731aba8e5b6b8cfee0e36bcb77b86a22 308 SUPERFAMILY SSF111331 2 308 1.98E-54 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A4R43_23120 731aba8e5b6b8cfee0e36bcb77b86a22 308 SMART SM00046 2 136 1.2E-12 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4R43_23120 731aba8e5b6b8cfee0e36bcb77b86a22 308 Gene3D G3DSA:3.40.50.10330 1 130 2.6E-33 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A4R43_24790 daf3120739dbf0891cbfb0e39cc4076c 560 SUPERFAMILY SSF143975 4 377 5.1E-135 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_24790 daf3120739dbf0891cbfb0e39cc4076c 560 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 556 45.924 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_24790 daf3120739dbf0891cbfb0e39cc4076c 560 Pfam PF00920 Dehydratase family 35 553 2.2E-206 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_24790 daf3120739dbf0891cbfb0e39cc4076c 560 Gene3D G3DSA:3.50.30.80 378 527 1.1E-51 T 14-10-2018 A4R43_24790 daf3120739dbf0891cbfb0e39cc4076c 560 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_24790 daf3120739dbf0891cbfb0e39cc4076c 560 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 554 8.9E-217 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_24790 daf3120739dbf0891cbfb0e39cc4076c 560 SUPERFAMILY SSF52016 378 555 2.75E-54 T 14-10-2018 A4R43_24790 daf3120739dbf0891cbfb0e39cc4076c 560 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 464 475 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_06060 20cd2a6fee9f5f1e327aa62b67cb3438 294 Gene3D G3DSA:3.60.15.10 1 291 1.1E-69 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_06060 20cd2a6fee9f5f1e327aa62b67cb3438 294 SMART SM00849 58 269 2.0E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_06060 20cd2a6fee9f5f1e327aa62b67cb3438 294 SUPERFAMILY SSF56281 59 283 2.62E-35 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_06060 20cd2a6fee9f5f1e327aa62b67cb3438 294 Pfam PF00753 Metallo-beta-lactamase superfamily 58 269 2.2E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_07765 591f706e726c8063bdf3b58cc07d45a5 303 SUPERFAMILY SSF53474 13 254 7.09E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07765 591f706e726c8063bdf3b58cc07d45a5 303 Gene3D G3DSA:3.40.50.1820 3 273 6.8E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07765 591f706e726c8063bdf3b58cc07d45a5 303 Pfam PF07859 alpha/beta hydrolase fold 44 255 1.1E-22 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 377 647 8.9E-27 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 SUPERFAMILY SSF51395 2 367 1.01E-109 T 14-10-2018 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 Gene3D G3DSA:3.50.50.60 470 622 4.1E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 399 2.5E-5 T 14-10-2018 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 616 630 2.5E-5 T 14-10-2018 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 Gene3D G3DSA:3.40.50.720 376 661 4.1E-112 T 14-10-2018 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 SUPERFAMILY SSF51971 334 519 2.35E-42 T 14-10-2018 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 SUPERFAMILY SSF51905 461 645 2.14E-19 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 498 516 5.9E-12 T 14-10-2018 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 378 397 5.9E-12 T 14-10-2018 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 615 631 5.9E-12 T 14-10-2018 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 331 9.2E-81 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4R43_26490 6fea767792c35b57a3b8aa3350fa4c8e 667 Gene3D G3DSA:3.20.20.70 3 369 3.5E-122 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_35025 fdab5a244f302deb3f59d23b1c373c66 442 Gene3D G3DSA:3.40.50.12780 8 344 6.2E-64 T 14-10-2018 A4R43_35025 fdab5a244f302deb3f59d23b1c373c66 442 Pfam PF13193 AMP-binding enzyme C-terminal domain 363 435 3.6E-15 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_35025 fdab5a244f302deb3f59d23b1c373c66 442 ProSitePatterns PS00455 Putative AMP-binding domain signature. 123 134 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_35025 fdab5a244f302deb3f59d23b1c373c66 442 SUPERFAMILY SSF56801 10 442 9.42E-92 T 14-10-2018 A4R43_35025 fdab5a244f302deb3f59d23b1c373c66 442 Pfam PF00501 AMP-binding enzyme 122 351 9.8E-43 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_35025 fdab5a244f302deb3f59d23b1c373c66 442 Gene3D G3DSA:3.30.300.30 353 442 6.4E-20 T 14-10-2018 A4R43_05710 dea999bb826540518c887b9cddd8c9dc 252 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 199 1.4E-20 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_05710 dea999bb826540518c887b9cddd8c9dc 252 Gene3D G3DSA:3.20.20.60 3 251 9.9E-52 T 14-10-2018 A4R43_05710 dea999bb826540518c887b9cddd8c9dc 252 SUPERFAMILY SSF51621 7 244 1.05E-53 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_33370 63ac88207f04a625bae7f0baf66ffed9 347 Gene3D G3DSA:3.30.360.10 128 291 1.1E-83 T 14-10-2018 A4R43_33370 63ac88207f04a625bae7f0baf66ffed9 347 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 122 3.9E-23 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_33370 63ac88207f04a625bae7f0baf66ffed9 347 SUPERFAMILY SSF55347 129 260 1.4E-15 T 14-10-2018 A4R43_33370 63ac88207f04a625bae7f0baf66ffed9 347 Gene3D G3DSA:3.40.50.720 6 323 1.1E-83 T 14-10-2018 A4R43_33370 63ac88207f04a625bae7f0baf66ffed9 347 SUPERFAMILY SSF51735 3 151 1.61E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_10680 4e9254f1cc3a575899945bf7ee0ea25f 378 SUPERFAMILY SSF53092 12 149 1.24E-23 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4R43_10680 4e9254f1cc3a575899945bf7ee0ea25f 378 Pfam PF01321 Creatinase/Prolidase N-terminal domain 19 151 1.9E-14 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A4R43_10680 4e9254f1cc3a575899945bf7ee0ea25f 378 Gene3D G3DSA:3.90.230.10 149 378 7.8E-81 T 14-10-2018 A4R43_10680 4e9254f1cc3a575899945bf7ee0ea25f 378 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 308 320 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A4R43_10680 4e9254f1cc3a575899945bf7ee0ea25f 378 Pfam PF00557 Metallopeptidase family M24 159 362 8.7E-63 T 14-10-2018 IPR000994 Peptidase M24 A4R43_10680 4e9254f1cc3a575899945bf7ee0ea25f 378 Gene3D G3DSA:3.40.350.10 6 148 5.7E-33 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4R43_10680 4e9254f1cc3a575899945bf7ee0ea25f 378 SUPERFAMILY SSF55920 150 376 3.53E-73 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like A4R43_41395 28c97503fa19c4d24d5802cdac036fe9 188 Gene3D G3DSA:1.20.1260.20 12 185 1.7E-6 T 14-10-2018 IPR038332 PPE superfamily A4R43_41395 28c97503fa19c4d24d5802cdac036fe9 188 SUPERFAMILY SSF140459 14 184 1.46E-7 T 14-10-2018 A4R43_05835 db2bc752e85e25f63f67c055895ca28e 447 SUPERFAMILY SSF103473 26 429 2.62E-34 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_05835 db2bc752e85e25f63f67c055895ca28e 447 Pfam PF07690 Major Facilitator Superfamily 52 332 4.9E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_05835 db2bc752e85e25f63f67c055895ca28e 447 Gene3D G3DSA:1.20.1250.20 27 223 1.9E-13 T 14-10-2018 A4R43_05835 db2bc752e85e25f63f67c055895ca28e 447 Gene3D G3DSA:1.20.1250.20 245 432 1.3E-9 T 14-10-2018 A4R43_11795 9691adc3d9638d92d0441afa7b3f00a3 317 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 4 276 9.6E-53 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11795 9691adc3d9638d92d0441afa7b3f00a3 317 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 235 254 3.1E-6 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11795 9691adc3d9638d92d0441afa7b3f00a3 317 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 78 94 3.1E-6 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11795 9691adc3d9638d92d0441afa7b3f00a3 317 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 116 140 3.1E-6 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11795 9691adc3d9638d92d0441afa7b3f00a3 317 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 165 183 3.1E-6 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11795 9691adc3d9638d92d0441afa7b3f00a3 317 Pfam PF02470 MlaD protein 28 100 6.4E-13 T 14-10-2018 IPR003399 Mce/MlaD A4R43_35165 77f30ad219b844ab107a6d5090696824 226 Pfam PF13305 WHG domain 96 170 3.4E-12 T 14-10-2018 IPR025996 WHG domain A4R43_35165 77f30ad219b844ab107a6d5090696824 226 SUPERFAMILY SSF46689 12 92 1.4E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35165 77f30ad219b844ab107a6d5090696824 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 67 5.6E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35165 77f30ad219b844ab107a6d5090696824 226 SUPERFAMILY SSF48498 93 190 4.0E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_35165 77f30ad219b844ab107a6d5090696824 226 Gene3D G3DSA:1.10.357.10 5 191 8.9E-42 T 14-10-2018 A4R43_16360 cb87a074a2efc291e12fa1451afca805 316 ProSitePatterns PS01125 ROK family signature. 124 151 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_16360 cb87a074a2efc291e12fa1451afca805 316 Gene3D G3DSA:3.30.420.40 116 288 1.2E-96 T 14-10-2018 A4R43_16360 cb87a074a2efc291e12fa1451afca805 316 Gene3D G3DSA:3.30.420.40 1 301 1.2E-96 T 14-10-2018 A4R43_16360 cb87a074a2efc291e12fa1451afca805 316 Pfam PF00480 ROK family 1 306 9.9E-72 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_16360 cb87a074a2efc291e12fa1451afca805 316 SUPERFAMILY SSF53067 1 307 2.68E-61 T 14-10-2018 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 Gene3D G3DSA:3.90.380.10 234 380 4.9E-27 T 14-10-2018 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 Gene3D G3DSA:3.90.380.10 173 233 1.1E-16 T 14-10-2018 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 SUPERFAMILY SSF50022 20 157 2.88E-47 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 Gene3D G3DSA:2.102.10.10 41 166 1.7E-37 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 SUPERFAMILY SSF55961 180 376 7.46E-40 T 14-10-2018 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 186 379 6.3E-41 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 Pfam PF00355 Rieske [2Fe-2S] domain 43 128 3.5E-20 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 28 53 8.1E-24 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 58 73 8.1E-24 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 79 99 8.1E-24 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 186 208 8.1E-24 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4R43_09665 05146169d1600991ac04722e6ed60e8d 380 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 101 121 8.1E-24 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4R43_22505 64229542810750ad6833c9edc0195caf 135 Gene3D G3DSA:3.30.70.1060 1 130 4.1E-30 T 14-10-2018 A4R43_22505 64229542810750ad6833c9edc0195caf 135 Pfam PF03795 YCII-related domain 1 122 1.2E-14 T 14-10-2018 IPR005545 YCII-related A4R43_22505 64229542810750ad6833c9edc0195caf 135 SUPERFAMILY SSF54909 1 127 1.45E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_08460 cd1faa3856ac41b09778059280fdfc37 314 PIRSF PIRSF016838 1 54 0.0037 T 14-10-2018 IPR028349 Protein PafC A4R43_08460 cd1faa3856ac41b09778059280fdfc37 314 PIRSF PIRSF016838 68 314 3.0E-20 T 14-10-2018 IPR028349 Protein PafC A4R43_08460 cd1faa3856ac41b09778059280fdfc37 314 Pfam PF08279 HTH domain 11 56 2.5E-12 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_08460 cd1faa3856ac41b09778059280fdfc37 314 Pfam PF13280 WYL domain 137 307 2.3E-31 T 14-10-2018 IPR026881 WYL domain A4R43_08460 cd1faa3856ac41b09778059280fdfc37 314 SUPERFAMILY SSF46785 2 59 5.18E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08460 cd1faa3856ac41b09778059280fdfc37 314 Gene3D G3DSA:1.10.10.10 1 63 1.9E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 180 1.1E-4 T 14-10-2018 A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 5.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 5.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 3.1E-53 T 14-10-2018 A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 SUPERFAMILY SSF51735 7 244 6.82E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38370 59bc2a58a90ffd50d98bb8ade7c57bd9 250 Gene3D G3DSA:3.40.50.720 6 249 3.9E-71 T 14-10-2018 A4R43_00795 adc60620bc2aa190c13fc290a52cf00f 245 Pfam PF13649 Methyltransferase domain 55 148 3.2E-19 T 14-10-2018 A4R43_00795 adc60620bc2aa190c13fc290a52cf00f 245 Gene3D G3DSA:3.40.50.150 9 209 1.7E-47 T 14-10-2018 A4R43_00795 adc60620bc2aa190c13fc290a52cf00f 245 SUPERFAMILY SSF53335 31 190 2.74E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_37205 4ffdc7d8638502d306fd8454f5e95e80 403 SUPERFAMILY SSF47203 245 384 6.47E-7 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_37205 4ffdc7d8638502d306fd8454f5e95e80 403 SUPERFAMILY SSF56645 12 215 2.23E-28 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_37205 4ffdc7d8638502d306fd8454f5e95e80 403 Gene3D G3DSA:1.10.540.10 3 118 2.1E-28 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_37205 4ffdc7d8638502d306fd8454f5e95e80 403 Gene3D G3DSA:1.20.140.10 223 403 9.2E-30 T 14-10-2018 A4R43_37205 4ffdc7d8638502d306fd8454f5e95e80 403 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 252 384 2.6E-17 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4R43_37205 4ffdc7d8638502d306fd8454f5e95e80 403 PIRSF PIRSF016578 2 400 2.3E-81 T 14-10-2018 A4R43_37205 4ffdc7d8638502d306fd8454f5e95e80 403 Gene3D G3DSA:2.40.110.10 122 215 9.7E-27 T 14-10-2018 A4R43_37205 4ffdc7d8638502d306fd8454f5e95e80 403 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 95 2.2E-5 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_33530 f2318b165a61023fedce5ce275e2ca53 116 SMART SM00345 17 76 5.9E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_33530 f2318b165a61023fedce5ce275e2ca53 116 Gene3D G3DSA:1.10.10.10 10 116 1.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_33530 f2318b165a61023fedce5ce275e2ca53 116 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 3.1E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_33530 f2318b165a61023fedce5ce275e2ca53 116 SUPERFAMILY SSF46785 6 80 3.96E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05510 9452713285efbb3bf9db4c26e4eb6af9 296 SUPERFAMILY SSF49899 36 257 4.75E-16 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_05510 9452713285efbb3bf9db4c26e4eb6af9 296 Gene3D G3DSA:2.60.120.200 45 267 1.7E-16 T 14-10-2018 A4R43_03625 be222814074dc2680b4ceb1dd0594734 331 SMART SM00382 39 246 3.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03625 be222814074dc2680b4ceb1dd0594734 331 Gene3D G3DSA:3.40.50.300 8 330 5.8E-93 T 14-10-2018 A4R43_03625 be222814074dc2680b4ceb1dd0594734 331 SUPERFAMILY SSF52540 11 259 1.41E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_03625 be222814074dc2680b4ceb1dd0594734 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 323 8.8E-27 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_03625 be222814074dc2680b4ceb1dd0594734 331 Pfam PF00005 ABC transporter 31 188 2.7E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_03625 be222814074dc2680b4ceb1dd0594734 331 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_03625 be222814074dc2680b4ceb1dd0594734 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 304 5.2E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_17330 f370d9014cd3ddf34551e75af5ecb120 316 Gene3D G3DSA:3.40.190.10 18 142 1.1E-18 T 14-10-2018 A4R43_17330 f370d9014cd3ddf34551e75af5ecb120 316 Pfam PF09084 NMT1/THI5 like 40 249 4.7E-30 T 14-10-2018 IPR015168 SsuA/THI5-like A4R43_17330 f370d9014cd3ddf34551e75af5ecb120 316 Gene3D G3DSA:3.40.190.10 143 314 2.3E-29 T 14-10-2018 A4R43_17330 f370d9014cd3ddf34551e75af5ecb120 316 SUPERFAMILY SSF53850 28 251 2.66E-41 T 14-10-2018 A4R43_34005 9d857c1097733835c7a625ff174fb2d1 251 PIRSF PIRSF001430 6 245 2.9E-51 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_34005 9d857c1097733835c7a625ff174fb2d1 251 Gene3D G3DSA:3.30.70.660 91 231 2.1E-31 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A4R43_34005 9d857c1097733835c7a625ff174fb2d1 251 Pfam PF01416 tRNA pseudouridine synthase 129 229 1.4E-21 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_34005 9d857c1097733835c7a625ff174fb2d1 251 Gene3D G3DSA:3.30.70.580 2 90 1.4E-13 T 14-10-2018 A4R43_34005 9d857c1097733835c7a625ff174fb2d1 251 SUPERFAMILY SSF55120 10 235 8.63E-51 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_03210 09eb3623d5a5e8411880ca63fdfa4de0 396 Gene3D G3DSA:3.40.640.10 31 297 5.2E-82 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_03210 09eb3623d5a5e8411880ca63fdfa4de0 396 Pfam PF00266 Aminotransferase class-V 32 387 7.8E-41 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_03210 09eb3623d5a5e8411880ca63fdfa4de0 396 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 208 228 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A4R43_03210 09eb3623d5a5e8411880ca63fdfa4de0 396 Gene3D G3DSA:3.90.1150.10 22 387 5.2E-82 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_03210 09eb3623d5a5e8411880ca63fdfa4de0 396 SUPERFAMILY SSF53383 12 394 1.51E-75 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_27315 aa9188a3d1e262887483ad5a7c333bd5 397 SUPERFAMILY SSF103473 7 384 4.84E-35 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_27315 aa9188a3d1e262887483ad5a7c333bd5 397 Pfam PF07690 Major Facilitator Superfamily 20 290 2.3E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_27315 aa9188a3d1e262887483ad5a7c333bd5 397 Gene3D G3DSA:1.20.1250.20 14 384 5.7E-31 T 14-10-2018 A4R43_22105 8cbf860e394115aead9528892578e407 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 473 4.7E-206 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22105 8cbf860e394115aead9528892578e407 474 SUPERFAMILY SSF55931 105 473 5.0E-137 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_22105 8cbf860e394115aead9528892578e407 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4R43_22105 8cbf860e394115aead9528892578e407 474 Gene3D G3DSA:3.30.590.10 107 462 1.1E-150 T 14-10-2018 A4R43_22105 8cbf860e394115aead9528892578e407 474 Gene3D G3DSA:3.10.20.70 4 106 5.7E-40 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22105 8cbf860e394115aead9528892578e407 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 3.3E-135 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22105 8cbf860e394115aead9528892578e407 474 SUPERFAMILY SSF54368 4 103 6.02E-34 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22105 8cbf860e394115aead9528892578e407 474 SMART SM01230 104 383 7.2E-151 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22105 8cbf860e394115aead9528892578e407 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4R43_22105 8cbf860e394115aead9528892578e407 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 8.6E-28 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4R43_22105 8cbf860e394115aead9528892578e407 474 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 390 402 - T 14-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_17410 825dc4e6f54f0d7dc6734f4a7d48da31 296 SMART SM00861 1 164 1.3E-23 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_17410 825dc4e6f54f0d7dc6734f4a7d48da31 296 SUPERFAMILY SSF52518 2 163 4.18E-36 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_17410 825dc4e6f54f0d7dc6734f4a7d48da31 296 SUPERFAMILY SSF52922 174 294 2.88E-13 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_17410 825dc4e6f54f0d7dc6734f4a7d48da31 296 Pfam PF02779 Transketolase, pyrimidine binding domain 1 160 6.1E-24 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_17410 825dc4e6f54f0d7dc6734f4a7d48da31 296 Gene3D G3DSA:3.40.50.920 173 296 8.0E-13 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_17410 825dc4e6f54f0d7dc6734f4a7d48da31 296 Gene3D G3DSA:3.40.50.970 1 168 7.2E-42 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 SUPERFAMILY SSF51905 142 318 7.07E-25 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 Pfam PF14759 Reductase C-terminal 325 408 1.3E-24 T 14-10-2018 IPR028202 Reductase, C-terminal A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 SUPERFAMILY SSF55424 317 409 1.3E-23 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 Gene3D G3DSA:3.50.50.60 114 239 6.0E-94 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 306 8.8E-51 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 Gene3D G3DSA:3.50.50.60 6 313 6.0E-94 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 Gene3D G3DSA:3.30.390.30 325 409 5.4E-26 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 9.7E-14 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 9.7E-14 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 9.7E-14 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 9.7E-14 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 SUPERFAMILY SSF51905 4 184 3.29E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 2.9E-21 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 2.9E-21 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.9E-21 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 2.9E-21 T 14-10-2018 A4R43_24320 be4b149db8c4aa9626861fd62c83dba6 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 2.9E-21 T 14-10-2018 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 1.8E-38 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 1.8E-38 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 1.8E-38 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 1.8E-38 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 1.8E-38 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.7E-57 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 Gene3D G3DSA:3.30.420.10 1 162 2.2E-48 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 SUPERFAMILY SSF53098 2 156 1.01E-43 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 153 2.0E-33 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 45.588 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4R43_04320 e3da0ac3959ae23a1898e91eda74e121 192 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 14-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 255 2.7E-60 T 14-10-2018 A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 SUPERFAMILY SSF51735 3 255 9.61E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 4.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 Gene3D G3DSA:3.40.50.720 1 257 2.5E-93 T 14-10-2018 A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 TIGRFAM TIGR02415 23BDH: acetoin reductases 4 257 9.0E-95 T 14-10-2018 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00650+1.1.1.304|MetaCyc: PWY-6389 A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08185 165a849953c5dbf1cde5f1d5593d6603 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16920 845efcdda8c6643c3f045788b1689933 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 270 2.6E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_16920 845efcdda8c6643c3f045788b1689933 304 SUPERFAMILY SSF161098 66 255 2.18E-36 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_16920 845efcdda8c6643c3f045788b1689933 304 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 64 163 1.6E-16 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_16920 845efcdda8c6643c3f045788b1689933 304 Gene3D G3DSA:1.10.3720.10 54 273 3.1E-45 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_19975 3ef4cc7d99f6752abf32d38e32c0620c 272 Gene3D G3DSA:3.20.20.30 115 272 6.7E-11 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_19975 3ef4cc7d99f6752abf32d38e32c0620c 272 Gene3D G3DSA:3.20.20.30 3 114 2.3E-18 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_19975 3ef4cc7d99f6752abf32d38e32c0620c 272 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 3 271 1.4E-85 T 14-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted A4R43_19975 3ef4cc7d99f6752abf32d38e32c0620c 272 Pfam PF00296 Luciferase-like monooxygenase 14 94 7.4E-17 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_19975 3ef4cc7d99f6752abf32d38e32c0620c 272 SUPERFAMILY SSF51679 3 272 6.62E-39 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_17570 c314547705324759563e6091de7423a8 239 Gene3D G3DSA:2.30.130.40 12 127 1.7E-29 T 14-10-2018 A4R43_17570 c314547705324759563e6091de7423a8 239 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 14 211 4.1E-23 T 14-10-2018 IPR003111 Lon, substrate-binding domain A4R43_17570 c314547705324759563e6091de7423a8 239 SMART SM00464 14 211 4.7E-17 T 14-10-2018 IPR003111 Lon, substrate-binding domain A4R43_17570 c314547705324759563e6091de7423a8 239 SUPERFAMILY SSF88697 14 210 4.72E-37 T 14-10-2018 IPR015947 PUA-like superfamily A4R43_40645 aef7a33450ac5df2e831f51bd1e7d6a4 153 SMART SM00347 32 135 2.9E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40645 aef7a33450ac5df2e831f51bd1e7d6a4 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.8E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40645 aef7a33450ac5df2e831f51bd1e7d6a4 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.8E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40645 aef7a33450ac5df2e831f51bd1e7d6a4 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 2.8E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40645 aef7a33450ac5df2e831f51bd1e7d6a4 153 SUPERFAMILY SSF46785 5 146 3.27E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40645 aef7a33450ac5df2e831f51bd1e7d6a4 153 Gene3D G3DSA:1.10.10.10 6 149 1.7E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40645 aef7a33450ac5df2e831f51bd1e7d6a4 153 Pfam PF12802 MarR family 38 97 4.2E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_24445 2cee2f94b6bb82696309d4621324e1cf 456 Gene3D G3DSA:3.40.50.620 142 377 5.8E-27 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_24445 2cee2f94b6bb82696309d4621324e1cf 456 SUPERFAMILY SSF52402 144 368 2.26E-12 T 14-10-2018 A4R43_19440 d6b2351f878bc8653cc8a37e9e71cecd 168 Gene3D G3DSA:1.10.10.10 86 164 1.3E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19440 d6b2351f878bc8653cc8a37e9e71cecd 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 160 1.3E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_19440 d6b2351f878bc8653cc8a37e9e71cecd 168 SUPERFAMILY SSF88946 4 92 7.06E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_19440 d6b2351f878bc8653cc8a37e9e71cecd 168 Pfam PF08281 Sigma-70, region 4 107 158 7.6E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_19440 d6b2351f878bc8653cc8a37e9e71cecd 168 SUPERFAMILY SSF88659 92 161 1.23E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_19440 d6b2351f878bc8653cc8a37e9e71cecd 168 Pfam PF04542 Sigma-70 region 2 4 75 1.6E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_19440 d6b2351f878bc8653cc8a37e9e71cecd 168 Gene3D G3DSA:1.10.1740.10 1 72 8.3E-8 T 14-10-2018 A4R43_40530 b4d64def2e186c074c2b154c17418e2f 269 Gene3D G3DSA:1.10.3720.10 1 256 1.1E-55 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_40530 b4d64def2e186c074c2b154c17418e2f 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 262 5.9E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_40530 b4d64def2e186c074c2b154c17418e2f 269 SUPERFAMILY SSF161098 3 268 8.76E-64 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_24075 8c0a327d9cf57db6917ffb78ab39c344 285 Gene3D G3DSA:1.10.8.100 218 283 9.4E-21 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A4R43_24075 8c0a327d9cf57db6917ffb78ab39c344 285 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 22 279 1.4E-73 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A4R43_24075 8c0a327d9cf57db6917ffb78ab39c344 285 Gene3D G3DSA:3.40.50.150 3 214 9.0E-59 T 14-10-2018 A4R43_24075 8c0a327d9cf57db6917ffb78ab39c344 285 SUPERFAMILY SSF53335 22 283 5.33E-65 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_24075 8c0a327d9cf57db6917ffb78ab39c344 285 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 22 282 48.947 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A4R43_24075 8c0a327d9cf57db6917ffb78ab39c344 285 Pfam PF00398 Ribosomal RNA adenine dimethylase 26 279 2.9E-43 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A4R43_24075 8c0a327d9cf57db6917ffb78ab39c344 285 SMART SM00650 38 212 5.6E-65 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A4R43_24075 8c0a327d9cf57db6917ffb78ab39c344 285 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 54 81 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A4R43_25315 9eb11cf454e700b8829bdbeacf704853 445 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 1.4E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_25315 9eb11cf454e700b8829bdbeacf704853 445 SUPERFAMILY SSF53383 99 435 5.78E-62 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_25315 9eb11cf454e700b8829bdbeacf704853 445 Pfam PF00155 Aminotransferase class I and II 111 431 5.7E-14 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_25315 9eb11cf454e700b8829bdbeacf704853 445 Gene3D G3DSA:1.10.10.10 4 74 2.5E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25315 9eb11cf454e700b8829bdbeacf704853 445 SUPERFAMILY SSF46785 5 70 1.31E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_25315 9eb11cf454e700b8829bdbeacf704853 445 Gene3D G3DSA:3.90.1150.10 114 432 1.2E-57 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_25315 9eb11cf454e700b8829bdbeacf704853 445 SMART SM00345 7 66 2.1E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_25315 9eb11cf454e700b8829bdbeacf704853 445 Gene3D G3DSA:3.40.640.10 119 333 1.2E-57 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_03060 87b9e3372584d81cd4f610897e960df0 325 Gene3D G3DSA:3.20.20.70 1 325 4.0E-93 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_03060 87b9e3372584d81cd4f610897e960df0 325 Pfam PF03060 Nitronate monooxygenase 1 317 1.7E-69 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_03060 87b9e3372584d81cd4f610897e960df0 325 SUPERFAMILY SSF51412 1 320 8.39E-44 T 14-10-2018 A4R43_14100 b74ee384aef74cac2815e8bdac94da2a 538 SMART SM00382 34 234 7.8E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14100 b74ee384aef74cac2815e8bdac94da2a 538 SMART SM00382 367 535 1.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14100 b74ee384aef74cac2815e8bdac94da2a 538 Gene3D G3DSA:3.40.50.300 10 285 3.1E-55 T 14-10-2018 A4R43_14100 b74ee384aef74cac2815e8bdac94da2a 538 Gene3D G3DSA:3.40.50.300 361 532 3.3E-34 T 14-10-2018 A4R43_14100 b74ee384aef74cac2815e8bdac94da2a 538 SUPERFAMILY SSF52540 8 257 1.42E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14100 b74ee384aef74cac2815e8bdac94da2a 538 Pfam PF00005 ABC transporter 364 494 2.3E-19 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14100 b74ee384aef74cac2815e8bdac94da2a 538 SUPERFAMILY SSF52540 365 531 2.0E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14100 b74ee384aef74cac2815e8bdac94da2a 538 Pfam PF00005 ABC transporter 25 190 1.4E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_32555 9fde08bbacae9a1cd947e3ded14f77d6 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 38 115 5.1E-14 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_32555 9fde08bbacae9a1cd947e3ded14f77d6 148 Gene3D G3DSA:2.30.110.10 29 121 1.3E-9 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_32555 9fde08bbacae9a1cd947e3ded14f77d6 148 Pfam PF04075 F420H(2)-dependent quinone reductase 38 112 4.8E-9 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_26290 0b0ac3e3a3d13c8c7316980c592c92f1 178 SUPERFAMILY SSF109854 12 172 1.57E-34 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_26290 0b0ac3e3a3d13c8c7316980c592c92f1 178 Gene3D G3DSA:1.20.120.450 4 174 1.2E-26 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_26290 0b0ac3e3a3d13c8c7316980c592c92f1 178 Pfam PF04978 Protein of unknown function (DUF664) 29 174 1.6E-34 T 14-10-2018 IPR007061 Protein of unknown function DUF664 A4R43_31960 787cf02125a4eb38595b1516da58050d 328 Gene3D G3DSA:3.40.190.10 130 255 9.1E-67 T 14-10-2018 A4R43_31960 787cf02125a4eb38595b1516da58050d 328 PIRSF PIRSF017082 1 328 4.5E-90 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_31960 787cf02125a4eb38595b1516da58050d 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 71 327 7.8E-32 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_31960 787cf02125a4eb38595b1516da58050d 328 Gene3D G3DSA:3.40.190.150 37 320 9.1E-67 T 14-10-2018 A4R43_08780 ba726cc5aaa44c946d524339daf090b3 138 Gene3D G3DSA:3.40.140.10 3 115 3.9E-28 T 14-10-2018 A4R43_08780 ba726cc5aaa44c946d524339daf090b3 138 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 4.4E-15 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A4R43_08780 ba726cc5aaa44c946d524339daf090b3 138 SUPERFAMILY SSF53927 2 123 8.53E-32 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_22380 7e78cef7afb3483be29445bc9e940dc9 264 SUPERFAMILY SSF81336 87 257 1.06E-30 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22380 7e78cef7afb3483be29445bc9e940dc9 264 Gene3D G3DSA:1.20.120.220 87 264 4.6E-28 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22380 7e78cef7afb3483be29445bc9e940dc9 264 Hamap MF_01393 ATP synthase subunit a [atpB]. 18 263 12.64 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22380 7e78cef7afb3483be29445bc9e940dc9 264 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 33 258 1.4E-37 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22380 7e78cef7afb3483be29445bc9e940dc9 264 Pfam PF00119 ATP synthase A chain 37 256 7.7E-47 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22380 7e78cef7afb3483be29445bc9e940dc9 264 PRINTS PR00123 ATP synthase A subunit signature 243 258 1.1E-15 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22380 7e78cef7afb3483be29445bc9e940dc9 264 PRINTS PR00123 ATP synthase A subunit signature 95 111 1.1E-15 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22380 7e78cef7afb3483be29445bc9e940dc9 264 PRINTS PR00123 ATP synthase A subunit signature 181 203 1.1E-15 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_37905 db951f6e7fe169206f2e025fbbfe7ee0 402 SUPERFAMILY SSF53383 3 399 3.99E-77 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_37905 db951f6e7fe169206f2e025fbbfe7ee0 402 Hamap MF_01970 Kynureninase [kynU]. 1 401 31.735 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A4R43_37905 db951f6e7fe169206f2e025fbbfe7ee0 402 Gene3D G3DSA:3.40.640.10 42 305 2.8E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_37905 db951f6e7fe169206f2e025fbbfe7ee0 402 PIRSF PIRSF038800 1 401 3.8E-133 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A4R43_37905 db951f6e7fe169206f2e025fbbfe7ee0 402 Pfam PF00266 Aminotransferase class-V 108 367 3.9E-22 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_37905 db951f6e7fe169206f2e025fbbfe7ee0 402 Gene3D G3DSA:3.90.1150.10 9 398 2.8E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 10 66 1.5E-18 T 14-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 Pfam PF04023 FeoA domain 151 225 1.9E-19 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 Gene3D G3DSA:2.30.30.90 150 228 2.8E-11 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 SMART SM00529 30 129 5.9E-40 T 14-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 Gene3D G3DSA:1.10.60.10 78 144 4.1E-26 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 SUPERFAMILY SSF47979 69 141 1.44E-23 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 69 137 2.6E-27 T 14-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 SUPERFAMILY SSF46785 9 68 2.68E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 SMART SM00899 149 226 7.9E-17 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 Gene3D G3DSA:1.10.10.10 6 76 2.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25380 1fecd5686bc7f859408363d77c603cd6 229 SUPERFAMILY SSF50037 151 225 8.93E-8 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.1E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.1E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.1E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.1E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.1E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.1E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 SUPERFAMILY SSF51735 1 250 3.74E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 248 9.1E-57 T 14-10-2018 A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 Gene3D G3DSA:3.40.50.720 2 256 3.2E-75 T 14-10-2018 A4R43_01475 7720b9e3675b0afa5ba2cab0998fd855 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_24360 430c7887dcfd83f3b40686bede7e9aaa 338 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 18 74 2.7E-5 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_24360 430c7887dcfd83f3b40686bede7e9aaa 338 Gene3D G3DSA:1.20.140.10 183 323 1.7E-21 T 14-10-2018 A4R43_24360 430c7887dcfd83f3b40686bede7e9aaa 338 SUPERFAMILY SSF56645 7 172 5.36E-10 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_24360 430c7887dcfd83f3b40686bede7e9aaa 338 SUPERFAMILY SSF47203 186 319 1.77E-25 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_24360 430c7887dcfd83f3b40686bede7e9aaa 338 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 187 299 1.2E-17 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_24360 430c7887dcfd83f3b40686bede7e9aaa 338 Gene3D G3DSA:1.10.540.10 2 91 2.4E-13 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_23980 ccd97a4d705a6e495276102d93eca4ca 457 Pfam PF13701 Transposase DDE domain group 1 6 447 1.8E-27 T 14-10-2018 IPR025668 Transposase DDE domain A4R43_02465 4c189d5e0f38164c8ccecaa7af3c1ec7 171 Gene3D G3DSA:3.90.79.10 10 142 9.0E-26 T 14-10-2018 A4R43_02465 4c189d5e0f38164c8ccecaa7af3c1ec7 171 Pfam PF00293 NUDIX domain 18 131 1.9E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_02465 4c189d5e0f38164c8ccecaa7af3c1ec7 171 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_02465 4c189d5e0f38164c8ccecaa7af3c1ec7 171 PRINTS PR00502 NUDIX hydrolase family signature 43 57 2.2E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_02465 4c189d5e0f38164c8ccecaa7af3c1ec7 171 PRINTS PR00502 NUDIX hydrolase family signature 57 72 2.2E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_02465 4c189d5e0f38164c8ccecaa7af3c1ec7 171 SUPERFAMILY SSF55811 14 138 7.58E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_16835 9bb53cc65710bb766a6d9490d4a50836 166 SUPERFAMILY SSF46785 14 131 2.14E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_16835 9bb53cc65710bb766a6d9490d4a50836 166 Gene3D G3DSA:1.10.10.10 2 83 2.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_16835 9bb53cc65710bb766a6d9490d4a50836 166 Pfam PF12840 Helix-turn-helix domain 13 63 1.6E-8 T 14-10-2018 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 Gene3D G3DSA:3.30.565.10 179 321 1.9E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 SUPERFAMILY SSF47384 96 175 1.28E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 SUPERFAMILY SSF55874 165 320 1.83E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 SMART SM00387 216 321 1.3E-35 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 Gene3D G3DSA:1.10.8.500 59 108 5.4E-10 T 14-10-2018 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 281 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 267 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 SMART SM00304 60 112 2.7E-16 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 SMART SM00388 113 175 9.9E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 SUPERFAMILY SSF158472 62 108 4.97E-12 T 14-10-2018 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 Pfam PF00512 His Kinase A (phospho-acceptor) domain 114 175 1.8E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 Pfam PF00672 HAMP domain 62 108 7.3E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 Gene3D G3DSA:1.10.287.130 109 174 8.1E-19 T 14-10-2018 A4R43_25350 a399fd09ad68fd34d53cb6ab66a4d8a7 322 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 320 2.6E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 SMART SM01134 74 235 2.5E-57 T 14-10-2018 A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 SMART SM00420 8 60 2.1E-13 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 4.1E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 4.1E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 2.1E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 Pfam PF00455 DeoR C terminal sensor domain 77 234 1.3E-40 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 Gene3D G3DSA:1.10.10.10 7 101 5.8E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 SUPERFAMILY SSF46785 8 61 1.33E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04080 133e0e9d5abfeaf58661d611832a113c 255 SUPERFAMILY SSF100950 77 235 5.65E-25 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_05030 c9a7311b89dda1fa71cf20d9c9cd9612 311 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_05030 c9a7311b89dda1fa71cf20d9c9cd9612 311 SUPERFAMILY SSF52540 4 228 3.78E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05030 c9a7311b89dda1fa71cf20d9c9cd9612 311 SMART SM00382 33 210 8.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05030 c9a7311b89dda1fa71cf20d9c9cd9612 311 Pfam PF00005 ABC transporter 25 163 4.1E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_05030 c9a7311b89dda1fa71cf20d9c9cd9612 311 Gene3D G3DSA:3.40.50.300 1 238 2.5E-57 T 14-10-2018 A4R43_19425 edaaf68180f0fa0538a29716b166d2ae 149 Pfam PF04138 GtrA-like protein 25 141 1.4E-11 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 Gene3D G3DSA:1.10.3860.10 7 422 1.6E-111 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 Pfam PF00375 Sodium:dicarboxylate symporter family 17 405 3.2E-101 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 PRINTS PR00173 Glutamate-aspartate symporter signature 82 107 6.2E-31 T 14-10-2018 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 PRINTS PR00173 Glutamate-aspartate symporter signature 52 72 6.2E-31 T 14-10-2018 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 6.2E-31 T 14-10-2018 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 6.2E-31 T 14-10-2018 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 PRINTS PR00173 Glutamate-aspartate symporter signature 11 31 6.2E-31 T 14-10-2018 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 6.2E-31 T 14-10-2018 A4R43_25425 3cb292283760310c730ffbfc1a5f76c2 447 SUPERFAMILY SSF118215 17 406 4.45E-106 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4R43_26710 13614c1b9b2c1f23d7aaec5f143695b2 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 71 1.0E-17 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4R43_26710 13614c1b9b2c1f23d7aaec5f143695b2 103 SUPERFAMILY SSF54909 1 94 1.04E-24 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_26710 13614c1b9b2c1f23d7aaec5f143695b2 103 Gene3D G3DSA:3.30.70.100 1 97 1.2E-34 T 14-10-2018 A4R43_30045 18f8722dee3a7fe30db88592e6e69860 107 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 101 6.7E-21 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_30045 18f8722dee3a7fe30db88592e6e69860 107 Gene3D G3DSA:3.90.226.10 1 105 4.4E-31 T 14-10-2018 A4R43_30045 18f8722dee3a7fe30db88592e6e69860 107 SUPERFAMILY SSF52096 6 101 1.28E-29 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 Gene3D G3DSA:1.10.8.10 146 195 5.5E-21 T 14-10-2018 A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 SUPERFAMILY SSF47781 65 134 4.73E-20 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 SUPERFAMILY SSF46929 148 198 3.27E-10 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 Gene3D G3DSA:1.10.150.20 67 137 1.4E-22 T 14-10-2018 A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 Gene3D G3DSA:2.40.50.140 1 65 1.2E-25 T 14-10-2018 A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 Pfam PF01330 RuvA N terminal domain 1 61 1.5E-19 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 Pfam PF14520 Helix-hairpin-helix domain 71 129 4.3E-15 T 14-10-2018 A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 SUPERFAMILY SSF50249 1 62 3.03E-14 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 192 3.6E-40 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 Pfam PF07499 RuvA, C-terminal domain 148 195 2.9E-12 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A4R43_04325 acbbf88e324fa20a5c929c621c0d7791 199 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 29.216 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A4R43_14670 8bc8e9ac1390be554663dcbe2393e935 643 Gene3D G3DSA:3.40.50.1820 398 643 1.2E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14670 8bc8e9ac1390be554663dcbe2393e935 643 Gene3D G3DSA:2.120.10.30 156 366 7.3E-11 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_14670 8bc8e9ac1390be554663dcbe2393e935 643 Gene3D G3DSA:2.120.10.30 39 155 1.7E-16 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_14670 8bc8e9ac1390be554663dcbe2393e935 643 Pfam PF00326 Prolyl oligopeptidase family 435 642 1.9E-43 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_14670 8bc8e9ac1390be554663dcbe2393e935 643 SUPERFAMILY SSF53474 396 642 5.08E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14670 8bc8e9ac1390be554663dcbe2393e935 643 SUPERFAMILY SSF82171 18 279 7.06E-26 T 14-10-2018 A4R43_14670 8bc8e9ac1390be554663dcbe2393e935 643 Pfam PF07676 WD40-like Beta Propeller Repeat 104 128 0.022 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_14670 8bc8e9ac1390be554663dcbe2393e935 643 Pfam PF07676 WD40-like Beta Propeller Repeat 50 77 7.0E-4 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_37150 d3830b628e78435f0856bb8eb3dabad6 453 SUPERFAMILY SSF51556 57 379 1.8E-80 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_37150 d3830b628e78435f0856bb8eb3dabad6 453 Gene3D G3DSA:3.20.20.140 56 418 4.0E-127 T 14-10-2018 A4R43_37150 d3830b628e78435f0856bb8eb3dabad6 453 ProSitePatterns PS00483 Dihydroorotase signature 2. 309 320 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_37150 d3830b628e78435f0856bb8eb3dabad6 453 Pfam PF01979 Amidohydrolase family 53 432 1.4E-27 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_37150 d3830b628e78435f0856bb8eb3dabad6 453 SUPERFAMILY SSF51338 7 447 8.65E-31 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_37150 d3830b628e78435f0856bb8eb3dabad6 453 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 24 433 5.7E-89 T 14-10-2018 A4R43_37150 d3830b628e78435f0856bb8eb3dabad6 453 Gene3D G3DSA:2.30.40.10 8 433 4.0E-127 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_06290 5359a29b5accfa2fe4dff4314df822da 167 SUPERFAMILY SSF54292 4 89 5.77E-24 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_06290 5359a29b5accfa2fe4dff4314df822da 167 Gene3D G3DSA:3.10.20.30 1 75 2.8E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_06290 5359a29b5accfa2fe4dff4314df822da 167 Gene3D G3DSA:1.10.150.120 79 167 2.0E-36 T 14-10-2018 A4R43_06290 5359a29b5accfa2fe4dff4314df822da 167 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 64 4.5E-9 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_06290 5359a29b5accfa2fe4dff4314df822da 167 SUPERFAMILY SSF47741 86 167 1.03E-27 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_06290 5359a29b5accfa2fe4dff4314df822da 167 Pfam PF01799 [2Fe-2S] binding domain 75 162 5.6E-30 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_06290 5359a29b5accfa2fe4dff4314df822da 167 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_09610 1df9905e15750797866b95a4392cb626 282 Gene3D G3DSA:3.40.50.170 86 281 2.1E-70 T 14-10-2018 A4R43_09610 1df9905e15750797866b95a4392cb626 282 Pfam PF00551 Formyl transferase 87 263 2.2E-39 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_09610 1df9905e15750797866b95a4392cb626 282 Gene3D G3DSA:3.30.70.260 2 85 1.3E-25 T 14-10-2018 A4R43_09610 1df9905e15750797866b95a4392cb626 282 SUPERFAMILY SSF53328 87 281 1.44E-62 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_09610 1df9905e15750797866b95a4392cb626 282 PIRSF PIRSF036480 2 282 3.7E-105 T 14-10-2018 A4R43_09610 1df9905e15750797866b95a4392cb626 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 87 109 5.7E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_09610 1df9905e15750797866b95a4392cb626 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 109 136 5.7E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_09610 1df9905e15750797866b95a4392cb626 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 255 280 5.7E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_09610 1df9905e15750797866b95a4392cb626 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 39 51 5.7E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_09610 1df9905e15750797866b95a4392cb626 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 233 255 5.7E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_09610 1df9905e15750797866b95a4392cb626 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 7 33 5.7E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_09610 1df9905e15750797866b95a4392cb626 282 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 2 281 44.5 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_09610 1df9905e15750797866b95a4392cb626 282 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 6 281 6.9E-94 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_09610 1df9905e15750797866b95a4392cb626 282 SUPERFAMILY SSF55021 4 81 1.67E-16 T 14-10-2018 A4R43_07225 0389cdec4a92222df31193a646247f8f 137 Pfam PF13279 Thioesterase-like superfamily 8 119 1.1E-12 T 14-10-2018 A4R43_07225 0389cdec4a92222df31193a646247f8f 137 Gene3D G3DSA:3.10.129.10 3 130 5.8E-28 T 14-10-2018 A4R43_07225 0389cdec4a92222df31193a646247f8f 137 SUPERFAMILY SSF54637 4 129 1.26E-29 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_25540 b5257abb3056911b318a76ee54feaa2c 310 Pfam PF00294 pfkB family carbohydrate kinase 29 301 3.6E-44 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_25540 b5257abb3056911b318a76ee54feaa2c 310 SUPERFAMILY SSF53613 2 303 2.81E-63 T 14-10-2018 IPR029056 Ribokinase-like A4R43_25540 b5257abb3056911b318a76ee54feaa2c 310 Gene3D G3DSA:3.40.1190.20 1 309 9.6E-75 T 14-10-2018 IPR029056 Ribokinase-like A4R43_25540 b5257abb3056911b318a76ee54feaa2c 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_29945 7e5c2f3941a2fd4d8cc4fe1a814465bd 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 3.2E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_29945 7e5c2f3941a2fd4d8cc4fe1a814465bd 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_29945 7e5c2f3941a2fd4d8cc4fe1a814465bd 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_29945 7e5c2f3941a2fd4d8cc4fe1a814465bd 215 SUPERFAMILY SSF48498 85 204 2.96E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_29945 7e5c2f3941a2fd4d8cc4fe1a814465bd 215 SUPERFAMILY SSF46689 15 76 7.98E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_29945 7e5c2f3941a2fd4d8cc4fe1a814465bd 215 Gene3D G3DSA:1.10.10.60 7 66 5.5E-16 T 14-10-2018 A4R43_29945 7e5c2f3941a2fd4d8cc4fe1a814465bd 215 Gene3D G3DSA:1.10.357.10 67 212 5.3E-26 T 14-10-2018 A4R43_29945 7e5c2f3941a2fd4d8cc4fe1a814465bd 215 Pfam PF16859 Bacterial transcriptional repressor C-terminal 84 201 4.8E-10 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_15700 3041dc4f0308fbbc07ba1b1d93bd2316 286 PIRSF PIRSF007580 1 286 1.0E-117 T 14-10-2018 IPR016516 Uncharacterised conserved protein UCP07580 A4R43_15700 3041dc4f0308fbbc07ba1b1d93bd2316 286 Pfam PF10118 Predicted metal-dependent hydrolase 12 266 5.1E-81 T 14-10-2018 IPR016516 Uncharacterised conserved protein UCP07580 A4R43_34570 71e23feebed2a143a19659f7e11fc3bb 393 Gene3D G3DSA:1.20.1250.20 8 200 2.2E-32 T 14-10-2018 A4R43_34570 71e23feebed2a143a19659f7e11fc3bb 393 Gene3D G3DSA:1.20.1250.20 201 383 5.7E-18 T 14-10-2018 A4R43_34570 71e23feebed2a143a19659f7e11fc3bb 393 SUPERFAMILY SSF103473 7 382 1.26E-61 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_34570 71e23feebed2a143a19659f7e11fc3bb 393 Pfam PF07690 Major Facilitator Superfamily 11 322 1.1E-42 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_12525 4d89af09ba3dc68c96d49702a16aa220 184 Gene3D G3DSA:3.40.30.10 50 184 2.6E-33 T 14-10-2018 A4R43_12525 4d89af09ba3dc68c96d49702a16aa220 184 SUPERFAMILY SSF52833 55 178 1.14E-28 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_12525 4d89af09ba3dc68c96d49702a16aa220 184 Pfam PF00578 AhpC/TSA family 55 163 2.7E-16 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 SUPERFAMILY SSF51905 295 424 5.57E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13025 9893b421f41f03543df250f55938c5c0 441 SUPERFAMILY SSF51905 2 217 6.91E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PIRSF PIRSF000332 2 427 1.7E-84 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 Gene3D G3DSA:3.50.50.60 2 380 1.9E-79 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13025 9893b421f41f03543df250f55938c5c0 441 Pfam PF00743 Flavin-binding monooxygenase-like 4 425 4.1E-78 T 14-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 103 115 4.7E-33 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 348 365 4.7E-33 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 132 148 4.7E-33 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 54 72 4.7E-33 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 189 204 4.7E-33 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 4 20 4.7E-33 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 302 329 4.7E-33 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_13025 9893b421f41f03543df250f55938c5c0 441 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 78 93 4.7E-33 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_12585 6e5cef074405aff441e722074311161c 340 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 260 6.7E-55 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_12585 6e5cef074405aff441e722074311161c 340 Gene3D G3DSA:3.40.50.720 9 330 1.5E-76 T 14-10-2018 A4R43_12585 6e5cef074405aff441e722074311161c 340 SUPERFAMILY SSF51735 4 330 3.4E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_30770 4a371147ae0cab351e635ff075fffc05 99 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 89 14.78 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4R43_30770 4a371147ae0cab351e635ff075fffc05 99 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 88 3.5E-19 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30770 4a371147ae0cab351e635ff075fffc05 99 SUPERFAMILY SSF54995 1 88 2.35E-25 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30770 4a371147ae0cab351e635ff075fffc05 99 Pfam PF01250 Ribosomal protein S6 1 86 1.2E-22 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30770 4a371147ae0cab351e635ff075fffc05 99 Gene3D G3DSA:3.30.70.60 1 98 5.2E-25 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A4R43_14695 c21273fc539d073714eda915ba424e31 718 Pfam PF04851 Type III restriction enzyme, res subunit 39 160 4.9E-9 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4R43_14695 c21273fc539d073714eda915ba424e31 718 Pfam PF00271 Helicase conserved C-terminal domain 456 566 5.5E-18 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_14695 c21273fc539d073714eda915ba424e31 718 SUPERFAMILY SSF52540 28 437 4.9E-131 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14695 c21273fc539d073714eda915ba424e31 718 Gene3D G3DSA:3.40.50.300 19 264 4.3E-74 T 14-10-2018 A4R43_14695 c21273fc539d073714eda915ba424e31 718 Hamap MF_00204 UvrABC system protein B [uvrB]. 26 708 42.904 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 A4R43_14695 c21273fc539d073714eda915ba424e31 718 SMART SM00490 482 568 2.1E-18 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_14695 c21273fc539d073714eda915ba424e31 718 Gene3D G3DSA:3.40.50.300 437 618 4.2E-49 T 14-10-2018 A4R43_14695 c21273fc539d073714eda915ba424e31 718 Pfam PF02151 UvrB/uvrC motif 675 708 2.9E-7 T 14-10-2018 IPR001943 UVR domain GO:0005515 A4R43_14695 c21273fc539d073714eda915ba424e31 718 Gene3D G3DSA:3.40.50.300 290 436 1.2E-51 T 14-10-2018 A4R43_14695 c21273fc539d073714eda915ba424e31 718 Gene3D G3DSA:4.10.860.10 659 710 5.1E-8 T 14-10-2018 A4R43_14695 c21273fc539d073714eda915ba424e31 718 Pfam PF12344 Ultra-violet resistance protein B 574 615 6.6E-21 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain A4R43_14695 c21273fc539d073714eda915ba424e31 718 SUPERFAMILY SSF52540 56 600 5.66E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14695 c21273fc539d073714eda915ba424e31 718 SMART SM00487 32 448 2.9E-26 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_14695 c21273fc539d073714eda915ba424e31 718 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 27 706 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 A4R43_14695 c21273fc539d073714eda915ba424e31 718 SUPERFAMILY SSF46600 662 710 8.5E-11 T 14-10-2018 IPR036876 UVR domain superfamily A4R43_05620 a850b10255dd941b8194df66985cfea1 194 SUPERFAMILY SSF55785 2 89 1.13E-11 T 14-10-2018 IPR035965 PAS domain superfamily A4R43_05620 a850b10255dd941b8194df66985cfea1 194 Gene3D G3DSA:3.30.450.20 1 101 5.0E-10 T 14-10-2018 A4R43_05620 a850b10255dd941b8194df66985cfea1 194 SMART SM00421 116 173 6.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05620 a850b10255dd941b8194df66985cfea1 194 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1 87 5.2E-9 T 14-10-2018 IPR000014 PAS domain A4R43_05620 a850b10255dd941b8194df66985cfea1 194 Pfam PF00196 Bacterial regulatory proteins, luxR family 118 172 8.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05620 a850b10255dd941b8194df66985cfea1 194 Gene3D G3DSA:1.10.10.10 111 179 3.9E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05620 a850b10255dd941b8194df66985cfea1 194 SUPERFAMILY SSF46894 112 180 7.48E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05620 a850b10255dd941b8194df66985cfea1 194 Pfam PF08448 PAS fold 2 67 1.4E-5 T 14-10-2018 IPR013656 PAS fold-4 A4R43_41260 dfdd0670f22c0eff5e1cc3189dfb223b 318 SUPERFAMILY SSF103481 218 307 1.06E-14 T 14-10-2018 A4R43_41260 dfdd0670f22c0eff5e1cc3189dfb223b 318 SUPERFAMILY SSF103481 51 151 2.09E-10 T 14-10-2018 A4R43_41260 dfdd0670f22c0eff5e1cc3189dfb223b 318 Pfam PF00892 EamA-like transporter family 15 149 4.4E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_41260 dfdd0670f22c0eff5e1cc3189dfb223b 318 Pfam PF00892 EamA-like transporter family 161 303 2.2E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_25490 805f3425c6d3c377f59b45f3ecf513d1 314 Pfam PF05239 PRC-barrel domain 6 75 8.4E-9 T 14-10-2018 IPR027275 PRC-barrel domain A4R43_25490 805f3425c6d3c377f59b45f3ecf513d1 314 SUPERFAMILY SSF50346 4 106 7.65E-21 T 14-10-2018 IPR011033 PRC-barrel-like superfamily A4R43_25490 805f3425c6d3c377f59b45f3ecf513d1 314 Pfam PF09557 Domain of unknown function (DUF2382) 198 305 2.8E-32 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 A4R43_25490 805f3425c6d3c377f59b45f3ecf513d1 314 Gene3D G3DSA:2.30.30.240 1 80 9.8E-9 T 14-10-2018 A4R43_25490 805f3425c6d3c377f59b45f3ecf513d1 314 TIGRFAM TIGR02271 TIGR02271: conserved domain 201 307 1.8E-15 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 A4R43_12710 d6cd32a054a6dda64b3907fa0077f055 80 SUPERFAMILY SSF47336 8 77 1.96E-12 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12710 d6cd32a054a6dda64b3907fa0077f055 80 Pfam PF00550 Phosphopantetheine attachment site 9 74 2.6E-8 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12710 d6cd32a054a6dda64b3907fa0077f055 80 Gene3D G3DSA:1.10.1200.10 1 79 1.7E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_03095 9e50ac7bf643b76f83dd95ca09a58fdd 132 Gene3D G3DSA:3.10.450.50 1 126 1.1E-28 T 14-10-2018 A4R43_03095 9e50ac7bf643b76f83dd95ca09a58fdd 132 Pfam PF12680 SnoaL-like domain 9 117 1.5E-14 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_03095 9e50ac7bf643b76f83dd95ca09a58fdd 132 SUPERFAMILY SSF54427 6 126 4.39E-23 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 Gene3D G3DSA:3.40.50.1220 184 346 1.3E-46 T 14-10-2018 A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 SUPERFAMILY SSF52518 363 540 6.74E-32 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 Gene3D G3DSA:3.40.50.970 360 553 2.2E-32 T 14-10-2018 A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 531 5.8E-19 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 SUPERFAMILY SSF52518 7 179 6.38E-36 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 323 2.8E-34 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 SUPERFAMILY SSF52467 182 342 3.47E-40 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 171 2.1E-32 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_12655 3f739c1488752a1d78c85c9c3f37ad7a 559 Gene3D G3DSA:3.40.50.970 2 183 5.3E-38 T 14-10-2018 A4R43_40490 f9da4bdcd86f52c40881b687acf5c315 434 Pfam PF12671 Putative amidase domain 267 410 1.2E-14 T 14-10-2018 IPR024301 Putative amidase domain A4R43_33680 63ed0416df5fea21031d0f79a3468790 382 Gene3D G3DSA:3.30.565.10 261 382 4.8E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_33680 63ed0416df5fea21031d0f79a3468790 382 Pfam PF07730 Histidine kinase 196 262 5.6E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_33680 63ed0416df5fea21031d0f79a3468790 382 SUPERFAMILY SSF55874 274 370 3.9E-7 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_32325 817a3f357ed6fdf997ed5d0da81cac23 186 Gene3D G3DSA:3.40.430.10 3 178 8.4E-30 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_32325 817a3f357ed6fdf997ed5d0da81cac23 186 Pfam PF01872 RibD C-terminal domain 7 172 1.8E-13 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_32325 817a3f357ed6fdf997ed5d0da81cac23 186 SUPERFAMILY SSF53597 8 179 2.09E-20 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_08280 50f9a17cd5da25d00d3c27c8c3f8835d 401 Pfam PF01494 FAD binding domain 7 167 1.6E-6 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_08280 50f9a17cd5da25d00d3c27c8c3f8835d 401 Gene3D G3DSA:3.30.9.50 43 275 3.5E-70 T 14-10-2018 A4R43_08280 50f9a17cd5da25d00d3c27c8c3f8835d 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 3.5E-9 T 14-10-2018 A4R43_08280 50f9a17cd5da25d00d3c27c8c3f8835d 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 3.5E-9 T 14-10-2018 A4R43_08280 50f9a17cd5da25d00d3c27c8c3f8835d 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.5E-9 T 14-10-2018 A4R43_08280 50f9a17cd5da25d00d3c27c8c3f8835d 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 3.5E-9 T 14-10-2018 A4R43_08280 50f9a17cd5da25d00d3c27c8c3f8835d 401 SUPERFAMILY SSF51905 7 371 1.58E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_08280 50f9a17cd5da25d00d3c27c8c3f8835d 401 Gene3D G3DSA:3.50.50.60 10 345 3.5E-70 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00250 dc6a45c62b56e747a308e4228be7a81e 413 SUPERFAMILY SSF53822 40 409 2.36E-80 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_00250 dc6a45c62b56e747a308e4228be7a81e 413 Gene3D G3DSA:3.40.50.2300 42 361 3.6E-81 T 14-10-2018 A4R43_00250 dc6a45c62b56e747a308e4228be7a81e 413 Pfam PF13458 Periplasmic binding protein 40 387 1.5E-61 T 14-10-2018 IPR028081 Leucine-binding protein domain A4R43_00250 dc6a45c62b56e747a308e4228be7a81e 413 Gene3D G3DSA:3.40.50.2300 159 296 3.6E-81 T 14-10-2018 A4R43_13005 d726088443213a8b9dd57ad3e27a2763 223 SUPERFAMILY SSF53335 10 178 3.61E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_13005 d726088443213a8b9dd57ad3e27a2763 223 Gene3D G3DSA:3.40.50.150 47 190 1.1E-10 T 14-10-2018 A4R43_27050 b9305ede308976dfccba7da07de9bfe5 418 Pfam PF07075 Protein of unknown function (DUF1343) 57 417 7.9E-128 T 14-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 A4R43_27050 b9305ede308976dfccba7da07de9bfe5 418 Gene3D G3DSA:3.90.1150.140 256 402 7.1E-128 T 14-10-2018 A4R43_27050 b9305ede308976dfccba7da07de9bfe5 418 Gene3D G3DSA:3.40.50.12170 38 417 7.1E-128 T 14-10-2018 A4R43_27050 b9305ede308976dfccba7da07de9bfe5 418 PIRSF PIRSF016719 6 418 3.1E-131 T 14-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 A4R43_16000 4a28b586246aa8c3a10f7775b33e613c 492 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 478 1.2E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_16000 4a28b586246aa8c3a10f7775b33e613c 492 Pfam PF00501 AMP-binding enzyme 13 392 5.5E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_16000 4a28b586246aa8c3a10f7775b33e613c 492 Gene3D G3DSA:3.30.300.310 390 490 8.6E-32 T 14-10-2018 A4R43_16000 4a28b586246aa8c3a10f7775b33e613c 492 SUPERFAMILY SSF56801 6 486 7.33E-144 T 14-10-2018 A4R43_16000 4a28b586246aa8c3a10f7775b33e613c 492 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_16000 4a28b586246aa8c3a10f7775b33e613c 492 Gene3D G3DSA:3.40.50.12780 1 389 1.2E-108 T 14-10-2018 A4R43_28145 d4ac3de9b62f38a9453579a1b540e871 174 Pfam PF04264 YceI-like domain 12 166 6.8E-32 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4R43_28145 d4ac3de9b62f38a9453579a1b540e871 174 SUPERFAMILY SSF101874 10 169 3.4E-33 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily A4R43_28145 d4ac3de9b62f38a9453579a1b540e871 174 Gene3D G3DSA:2.40.128.110 9 169 2.2E-34 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily A4R43_28145 d4ac3de9b62f38a9453579a1b540e871 174 SMART SM00867 11 168 1.3E-34 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 SUPERFAMILY SSF52743 151 573 6.28E-58 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 482 492 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 Gene3D G3DSA:3.40.50.200 136 575 3.5E-70 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 232 242 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 PRINTS PR00723 Subtilisin serine protease family (S8) signature 481 497 1.5E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 PRINTS PR00723 Subtilisin serine protease family (S8) signature 168 187 1.5E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 PRINTS PR00723 Subtilisin serine protease family (S8) signature 228 241 1.5E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 Pfam PF00082 Subtilase family 170 550 2.8E-40 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_23865 56f393f0751deab13b84b56e89ae931e 580 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 173 184 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_20225 de9107568b78c087c736b00bc51f6148 474 SMART SM00530 9 64 3.4E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_20225 de9107568b78c087c736b00bc51f6148 474 SUPERFAMILY SSF47413 4 66 1.13E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_20225 de9107568b78c087c736b00bc51f6148 474 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 312 468 1.9E-70 T 14-10-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator A4R43_20225 de9107568b78c087c736b00bc51f6148 474 Pfam PF06114 IrrE N-terminal-like domain 188 311 1.3E-18 T 14-10-2018 IPR010359 IrrE N-terminal-like domain A4R43_20225 de9107568b78c087c736b00bc51f6148 474 Pfam PF13560 Helix-turn-helix domain 7 61 6.4E-12 T 14-10-2018 A4R43_20225 de9107568b78c087c736b00bc51f6148 474 Gene3D G3DSA:1.10.260.40 5 82 3.1E-14 T 14-10-2018 A4R43_20225 de9107568b78c087c736b00bc51f6148 474 PIRSF PIRSF019251 1 473 1.5E-193 T 14-10-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 A4R43_18650 bde784ebb856de45e7918982efdb798f 402 Gene3D G3DSA:3.30.420.40 151 336 1.9E-101 T 14-10-2018 A4R43_18650 bde784ebb856de45e7918982efdb798f 402 Gene3D G3DSA:3.30.420.40 16 371 1.9E-101 T 14-10-2018 A4R43_18650 bde784ebb856de45e7918982efdb798f 402 SUPERFAMILY SSF53067 80 330 7.34E-11 T 14-10-2018 A4R43_18650 bde784ebb856de45e7918982efdb798f 402 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 9 376 33.3 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 A4R43_18650 bde784ebb856de45e7918982efdb798f 402 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 11 375 8.3E-103 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 A4R43_13180 1edecdc3caa6d9f83396767d87fd2c84 102 Gene3D G3DSA:1.10.357.10 1 100 3.3E-15 T 14-10-2018 A4R43_13180 1edecdc3caa6d9f83396767d87fd2c84 102 SUPERFAMILY SSF48498 1 100 3.56E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_13180 1edecdc3caa6d9f83396767d87fd2c84 102 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 1 98 1.4E-7 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_10600 057a8b3d7a4711dc6b4c8a285a751132 269 SMART SM00318 65 188 0.0027 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A4R43_10600 057a8b3d7a4711dc6b4c8a285a751132 269 SMART SM00894 233 269 1.4E-18 T 14-10-2018 IPR008613 Excalibur calcium-binding domain A4R43_10600 057a8b3d7a4711dc6b4c8a285a751132 269 Pfam PF05901 Excalibur calcium-binding domain 234 269 1.1E-13 T 14-10-2018 IPR008613 Excalibur calcium-binding domain A4R43_10600 057a8b3d7a4711dc6b4c8a285a751132 269 Gene3D G3DSA:2.40.50.90 63 190 3.7E-14 T 14-10-2018 IPR035437 SNase-like, OB-fold superfamily A4R43_10600 057a8b3d7a4711dc6b4c8a285a751132 269 SUPERFAMILY SSF50199 65 188 2.75E-15 T 14-10-2018 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 Gene3D G3DSA:1.10.1040.50 496 590 1.0E-32 T 14-10-2018 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 SUPERFAMILY SSF48179 493 589 7.23E-29 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 SUPERFAMILY SSF48179 188 290 4.59E-29 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 493 589 6.0E-32 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 284 4.6E-30 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 SUPERFAMILY SSF51735 310 490 1.94E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 312 490 8.5E-61 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 185 7.2E-63 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 SUPERFAMILY SSF51735 5 185 7.48E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 Gene3D G3DSA:1.10.1040.10 195 283 8.9E-31 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 Gene3D G3DSA:3.40.50.720 1 186 3.1E-65 T 14-10-2018 A4R43_22235 e7587e8c525fb27b47fdb940b3c6610b 590 Gene3D G3DSA:3.40.50.720 284 491 4.3E-66 T 14-10-2018 A4R43_25810 fba41d11a6a5df240a9349a5778089ca 920 SUPERFAMILY SSF55874 46 179 4.95E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25810 fba41d11a6a5df240a9349a5778089ca 920 Gene3D G3DSA:3.30.565.10 23 192 7.0E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_34305 2bc283a52a7855be01eed5fb9015bcf1 202 Gene3D G3DSA:1.10.10.60 1 68 8.3E-29 T 14-10-2018 A4R43_34305 2bc283a52a7855be01eed5fb9015bcf1 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.7E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34305 2bc283a52a7855be01eed5fb9015bcf1 202 SUPERFAMILY SSF48498 81 196 1.64E-27 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_34305 2bc283a52a7855be01eed5fb9015bcf1 202 SUPERFAMILY SSF46689 2 85 2.36E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_34305 2bc283a52a7855be01eed5fb9015bcf1 202 Gene3D G3DSA:1.10.357.10 72 199 1.0E-33 T 14-10-2018 A4R43_35725 c294cd6ffe5c5d9c3a1e07e25f705497 393 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_35725 c294cd6ffe5c5d9c3a1e07e25f705497 393 SUPERFAMILY SSF50331 237 389 3.64E-20 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_35725 c294cd6ffe5c5d9c3a1e07e25f705497 393 SUPERFAMILY SSF52540 4 243 1.73E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35725 c294cd6ffe5c5d9c3a1e07e25f705497 393 Pfam PF00005 ABC transporter 21 162 3.9E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_35725 c294cd6ffe5c5d9c3a1e07e25f705497 393 SMART SM00382 29 220 1.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_35725 c294cd6ffe5c5d9c3a1e07e25f705497 393 Gene3D G3DSA:3.40.50.300 4 222 4.6E-64 T 14-10-2018 A4R43_35725 c294cd6ffe5c5d9c3a1e07e25f705497 393 Gene3D G3DSA:2.40.50.140 287 373 2.6E-27 T 14-10-2018 A4R43_35725 c294cd6ffe5c5d9c3a1e07e25f705497 393 Gene3D G3DSA:2.40.50.940 223 382 2.6E-27 T 14-10-2018 A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 Gene3D G3DSA:2.180.10.10 802 1302 3.4E-34 T 14-10-2018 A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 639 662 0.0031 T 14-10-2018 IPR006530 YD repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1113 1138 4.5E-5 T 14-10-2018 IPR006530 YD repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 533 568 7.8E-6 T 14-10-2018 IPR006530 YD repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 619 659 2.7E-8 T 14-10-2018 IPR006530 YD repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 823 863 8.6E-12 T 14-10-2018 IPR006530 YD repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 865 904 1.3E-8 T 14-10-2018 IPR006530 YD repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 Gene3D G3DSA:3.90.930.1 523 683 1.6E-9 T 14-10-2018 A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 SUPERFAMILY SSF69304 454 665 6.93E-9 T 14-10-2018 A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 Pfam PF03527 RHS protein 1204 1231 6.0E-8 T 14-10-2018 IPR001826 RHS protein A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 PRINTS PR01217 Proline rich extensin signature 300 321 1.5E-10 T 14-10-2018 A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 PRINTS PR01217 Proline rich extensin signature 322 338 1.5E-10 T 14-10-2018 A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 PRINTS PR01217 Proline rich extensin signature 266 278 1.5E-10 T 14-10-2018 A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 Pfam PF05593 RHS Repeat 857 880 1.4E-4 T 14-10-2018 IPR031325 RHS repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 Pfam PF05593 RHS Repeat 865 902 4.2E-8 T 14-10-2018 IPR031325 RHS repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 Pfam PF05593 RHS Repeat 823 859 2.9E-10 T 14-10-2018 IPR031325 RHS repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 Pfam PF05593 RHS Repeat 619 655 2.5E-5 T 14-10-2018 IPR031325 RHS repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 Pfam PF05593 RHS Repeat 533 562 1.8E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_12175 6dd1a9fb1716033104d4bc6e67ea0395 1612 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1229 1302 2.7E-19 T 14-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 A4R43_16110 7b30f34e6a8662538f217448c9f113e0 259 SUPERFAMILY SSF52218 1 256 1.9E-63 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_16110 7b30f34e6a8662538f217448c9f113e0 259 Pfam PF02525 Flavodoxin-like fold 1 208 1.2E-55 T 14-10-2018 IPR003680 Flavodoxin-like fold A4R43_16110 7b30f34e6a8662538f217448c9f113e0 259 Gene3D G3DSA:3.40.50.360 1 255 8.5E-85 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_27375 3636d659a799d619dd08dd08b464c94f 322 Gene3D G3DSA:1.10.10.10 1 89 8.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27375 3636d659a799d619dd08dd08b464c94f 322 Gene3D G3DSA:3.40.190.10 91 284 9.0E-32 T 14-10-2018 A4R43_27375 3636d659a799d619dd08dd08b464c94f 322 SUPERFAMILY SSF53850 89 299 1.81E-27 T 14-10-2018 A4R43_27375 3636d659a799d619dd08dd08b464c94f 322 Gene3D G3DSA:3.40.190.10 168 270 9.0E-32 T 14-10-2018 A4R43_27375 3636d659a799d619dd08dd08b464c94f 322 Pfam PF03466 LysR substrate binding domain 88 296 2.5E-30 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_27375 3636d659a799d619dd08dd08b464c94f 322 SUPERFAMILY SSF46785 2 111 2.0E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_27375 3636d659a799d619dd08dd08b464c94f 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 SUPERFAMILY SSF53383 17 459 6.51E-98 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 74 93 7.0E-5 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 339 354 7.0E-5 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 382 401 7.0E-5 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 113 132 7.0E-5 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 Gene3D G3DSA:3.90.1150.170 26 452 2.1E-116 T 14-10-2018 A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 72 398 1.4E-35 T 14-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 287 308 - T 14-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A4R43_02750 0f756c2d1c665b6af3c535275eeb0a2d 460 Gene3D G3DSA:3.40.640.10 101 344 2.1E-116 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_08330 2bd0b17676afd78b40c5e1885ff4f302 407 Pfam PF05977 Transmembrane secretion effector 5 394 3.6E-30 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_08330 2bd0b17676afd78b40c5e1885ff4f302 407 SUPERFAMILY SSF103473 7 402 2.09E-38 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08330 2bd0b17676afd78b40c5e1885ff4f302 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 164 181 1.8E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_08330 2bd0b17676afd78b40c5e1885ff4f302 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 253 270 1.8E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_08330 2bd0b17676afd78b40c5e1885ff4f302 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 12 34 1.8E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_08330 2bd0b17676afd78b40c5e1885ff4f302 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 137 158 1.8E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_08330 2bd0b17676afd78b40c5e1885ff4f302 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 75 93 1.8E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4R43_08330 2bd0b17676afd78b40c5e1885ff4f302 407 Gene3D G3DSA:1.20.1250.20 9 395 6.6E-31 T 14-10-2018 A4R43_41570 68df6232d28a074a763fe8956c61a870 214 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 37 207 3.8E-51 T 14-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 A4R43_41570 68df6232d28a074a763fe8956c61a870 214 Gene3D G3DSA:3.40.50.300 36 208 6.6E-50 T 14-10-2018 A4R43_41570 68df6232d28a074a763fe8956c61a870 214 PIRSF PIRSF006135 35 211 3.0E-47 T 14-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 A4R43_41570 68df6232d28a074a763fe8956c61a870 214 SUPERFAMILY SSF52540 37 207 1.86E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20210 9ebc0dd4d4ead7e17877c4d2596b13e4 328 Pfam PF04389 Peptidase family M28 97 306 9.1E-47 T 14-10-2018 IPR007484 Peptidase M28 A4R43_20210 9ebc0dd4d4ead7e17877c4d2596b13e4 328 SUPERFAMILY SSF53187 41 311 5.74E-70 T 14-10-2018 A4R43_20210 9ebc0dd4d4ead7e17877c4d2596b13e4 328 Gene3D G3DSA:3.40.630.10 32 314 4.1E-82 T 14-10-2018 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 Gene3D G3DSA:3.40.630.10 153 483 4.9E-119 T 14-10-2018 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 Gene3D G3DSA:3.40.220.10 26 150 2.0E-10 T 14-10-2018 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 PRINTS PR00481 Cytosol aminopeptidase signature 357 372 8.8E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 PRINTS PR00481 Cytosol aminopeptidase signature 328 348 8.8E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 PRINTS PR00481 Cytosol aminopeptidase signature 269 290 8.8E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 PRINTS PR00481 Cytosol aminopeptidase signature 306 327 8.8E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 PRINTS PR00481 Cytosol aminopeptidase signature 247 264 8.8E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 SUPERFAMILY SSF53187 166 479 8.79E-104 T 14-10-2018 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 42 130 8.5E-7 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 171 476 6.6E-112 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 332 339 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4R43_35635 fbca64c43a7bbc2178abdc4201abd834 483 SUPERFAMILY SSF52949 37 141 4.53E-8 T 14-10-2018 A4R43_22905 c5bbd2e8a0bbffc5712a7c05c1812751 178 Gene3D G3DSA:3.40.630.30 1 159 3.9E-25 T 14-10-2018 A4R43_22905 c5bbd2e8a0bbffc5712a7c05c1812751 178 SUPERFAMILY SSF55729 6 165 4.53E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_22905 c5bbd2e8a0bbffc5712a7c05c1812751 178 Pfam PF00583 Acetyltransferase (GNAT) family 52 149 4.3E-8 T 14-10-2018 IPR000182 GNAT domain A4R43_13190 f8a71b3eaa071df0b4601ed3739d6939 259 SUPERFAMILY SSF81301 12 55 8.36E-7 T 14-10-2018 A4R43_13190 f8a71b3eaa071df0b4601ed3739d6939 259 Gene3D G3DSA:3.30.460.10 2 78 3.2E-7 T 14-10-2018 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 242 301 9.7E-26 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 SUPERFAMILY SSF47789 246 317 1.7E-23 T 14-10-2018 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 3.3E-115 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 3.2E-20 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 320 2.0E-23 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 Gene3D G3DSA:1.10.150.20 237 311 4.4E-28 T 14-10-2018 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 Gene3D G3DSA:3.30.1360.10 12 216 2.1E-84 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 SUPERFAMILY SSF56553 48 169 1.19E-42 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 34.711 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 SUPERFAMILY SSF55257 13 220 2.16E-26 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 SMART SM00662 18 225 1.6E-97 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 Gene3D G3DSA:2.170.120.12 48 168 2.1E-84 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33995 780c16ecfb99785ff6c2d32a44e81d75 357 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 1.9E-25 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 Gene3D G3DSA:2.40.30.110 280 362 1.7E-29 T 14-10-2018 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 Gene3D G3DSA:3.30.70.1400 51 137 2.0E-86 T 14-10-2018 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 SUPERFAMILY SSF103025 3 280 3.48E-99 T 14-10-2018 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 361 1.8E-109 T 14-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 Gene3D G3DSA:4.10.1250.10 237 278 1.1E-17 T 14-10-2018 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 SUPERFAMILY SSF101790 276 361 1.8E-24 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 PIRSF PIRSF006487 1 362 4.0E-97 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 265 356 3.0E-23 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 257 1.2E-91 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 Gene3D G3DSA:3.30.1360.120 4 235 2.0E-86 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4R43_19155 753a37db1936fe12d2fc2d3e08f68835 362 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 362 43.21 T 14-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4R43_31915 f78e7c448c59ddd3aa0a0f0468d676da 273 Gene3D G3DSA:1.10.260.40 1 61 4.0E-5 T 14-10-2018 A4R43_31915 f78e7c448c59ddd3aa0a0f0468d676da 273 SMART SM00530 6 61 0.0089 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_31915 f78e7c448c59ddd3aa0a0f0468d676da 273 SUPERFAMILY SSF47413 1 57 6.57E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_31915 f78e7c448c59ddd3aa0a0f0468d676da 273 Pfam PF13560 Helix-turn-helix domain 3 64 1.0E-13 T 14-10-2018 A4R43_38515 4912d232e1ad5f0052ce669d8ea795bb 144 PIRSF PIRSF001399 1 144 3.1E-48 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_38515 4912d232e1ad5f0052ce669d8ea795bb 144 Pfam PF01220 Dehydroquinase class II 4 138 8.4E-46 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_38515 4912d232e1ad5f0052ce669d8ea795bb 144 Gene3D G3DSA:3.40.50.9100 1 143 2.5E-50 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_38515 4912d232e1ad5f0052ce669d8ea795bb 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_38515 4912d232e1ad5f0052ce669d8ea795bb 144 SUPERFAMILY SSF52304 3 142 3.92E-49 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_38515 4912d232e1ad5f0052ce669d8ea795bb 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 50.892 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_38515 4912d232e1ad5f0052ce669d8ea795bb 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 139 1.0E-57 T 14-10-2018 A4R43_12990 8dc9a919015b51b22b768336e0dd9a12 110 SUPERFAMILY SSF81301 15 70 4.9E-7 T 14-10-2018 A4R43_12990 8dc9a919015b51b22b768336e0dd9a12 110 Gene3D G3DSA:3.30.460.40 9 92 5.8E-11 T 14-10-2018 A4R43_03430 468e823653e62fb572184d8e4d48083f 498 Pfam PF07690 Major Facilitator Superfamily 24 411 3.1E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_03430 468e823653e62fb572184d8e4d48083f 498 Gene3D G3DSA:1.20.1720.10 17 247 8.8E-39 T 14-10-2018 A4R43_03430 468e823653e62fb572184d8e4d48083f 498 SUPERFAMILY SSF103473 6 493 2.49E-65 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_23890 8b1a5ead912bb17a1aa82376efb9b670 541 Gene3D G3DSA:3.40.190.10 47 521 1.2E-102 T 14-10-2018 A4R43_23890 8b1a5ead912bb17a1aa82376efb9b670 541 Gene3D G3DSA:3.10.105.10 303 514 1.2E-102 T 14-10-2018 A4R43_23890 8b1a5ead912bb17a1aa82376efb9b670 541 PIRSF PIRSF002741 1 537 4.3E-77 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_23890 8b1a5ead912bb17a1aa82376efb9b670 541 SUPERFAMILY SSF53850 42 540 6.67E-98 T 14-10-2018 A4R43_23890 8b1a5ead912bb17a1aa82376efb9b670 541 Gene3D G3DSA:3.90.76.10 66 201 1.2E-102 T 14-10-2018 A4R43_23890 8b1a5ead912bb17a1aa82376efb9b670 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 462 5.7E-65 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_29305 5713e1549f4dcccb0bd21632ade5dfcd 214 SUPERFAMILY SSF56784 1 207 1.1E-35 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_29305 5713e1549f4dcccb0bd21632ade5dfcd 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 177 6.4E-11 T 14-10-2018 A4R43_29305 5713e1549f4dcccb0bd21632ade5dfcd 214 Gene3D G3DSA:3.40.50.1000 1 212 3.7E-30 T 14-10-2018 IPR023214 HAD superfamily A4R43_29305 5713e1549f4dcccb0bd21632ade5dfcd 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 172 7.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_16500 8878ec95f32e70de5e206bd5eea11cca 246 Gene3D G3DSA:3.20.20.10 1 244 1.1E-70 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_16500 8878ec95f32e70de5e206bd5eea11cca 246 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 85 99 - T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A4R43_16500 8878ec95f32e70de5e206bd5eea11cca 246 Pfam PF01168 Alanine racemase, N-terminal domain 13 240 1.0E-17 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_16500 8878ec95f32e70de5e206bd5eea11cca 246 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 11 240 26.1 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A4R43_16500 8878ec95f32e70de5e206bd5eea11cca 246 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 10 241 5.8E-44 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A4R43_16500 8878ec95f32e70de5e206bd5eea11cca 246 SUPERFAMILY SSF51419 4 239 3.92E-61 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_16500 8878ec95f32e70de5e206bd5eea11cca 246 PIRSF PIRSF004848 2 245 4.9E-61 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A4R43_02720 512708d8fab9c6b0396fa7914abd8dba 421 Gene3D G3DSA:3.40.50.2000 229 399 1.3E-113 T 14-10-2018 A4R43_02720 512708d8fab9c6b0396fa7914abd8dba 421 SUPERFAMILY SSF53756 3 415 1.51E-89 T 14-10-2018 A4R43_02720 512708d8fab9c6b0396fa7914abd8dba 421 Gene3D G3DSA:3.40.50.2000 3 401 1.3E-113 T 14-10-2018 A4R43_02720 512708d8fab9c6b0396fa7914abd8dba 421 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 237 398 6.5E-7 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_02720 512708d8fab9c6b0396fa7914abd8dba 421 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 127 1.8E-12 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_36910 4a218a1465456545241c69f5780b7d10 216 Gene3D G3DSA:3.40.225.10 2 216 3.6E-69 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_36910 4a218a1465456545241c69f5780b7d10 216 SMART SM01007 8 187 7.4E-57 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_36910 4a218a1465456545241c69f5780b7d10 216 SUPERFAMILY SSF53639 3 215 3.92E-60 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_36910 4a218a1465456545241c69f5780b7d10 216 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 187 4.9E-46 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_36995 c592a16834348999421073faa944547e 486 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 266 282 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_36995 c592a16834348999421073faa944547e 486 PIRSF PIRSF001109 1 486 5.2E-185 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_36995 c592a16834348999421073faa944547e 486 SMART SM00996 12 485 0.0 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_36995 c592a16834348999421073faa944547e 486 Gene3D G3DSA:3.40.50.1480 15 486 1.6E-234 T 14-10-2018 A4R43_36995 c592a16834348999421073faa944547e 486 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 13 478 8.6E-186 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_36995 c592a16834348999421073faa944547e 486 SUPERFAMILY SSF52283 11 486 2.95E-110 T 14-10-2018 A4R43_36995 c592a16834348999421073faa944547e 486 SUPERFAMILY SSF51735 244 406 9.87E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_36995 c592a16834348999421073faa944547e 486 SMART SM00997 244 406 1.7E-101 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_36995 c592a16834348999421073faa944547e 486 Gene3D G3DSA:3.40.50.720 247 407 1.6E-234 T 14-10-2018 A4R43_36995 c592a16834348999421073faa944547e 486 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 8 478 47.811 T 14-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A4R43_36995 c592a16834348999421073faa944547e 486 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 12 485 1.4E-142 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_36995 c592a16834348999421073faa944547e 486 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 244 406 1.6E-78 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_36995 c592a16834348999421073faa944547e 486 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 84 98 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4R43_03325 6e0ee0768e3cff0add669feff35841cd 166 SUPERFAMILY SSF69118 21 149 6.91E-25 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_03325 6e0ee0768e3cff0add669feff35841cd 166 Gene3D G3DSA:1.20.1290.10 16 153 7.2E-27 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_03325 6e0ee0768e3cff0add669feff35841cd 166 Pfam PF02627 Carboxymuconolactone decarboxylase family 19 103 1.3E-7 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_23290 7a9ff2081823f25f1d4fa462e34a5483 89 Pfam PF12005 Protein of unknown function (DUF3499) 1 85 9.7E-29 T 14-10-2018 IPR021888 Protein of unknown function DUF3499 A4R43_27900 08b10ae625b72039ccd25117e040c194 316 SUPERFAMILY SSF100939 2 257 7.46E-51 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily A4R43_27900 08b10ae625b72039ccd25117e040c194 316 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 2 256 33.13 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_27900 08b10ae625b72039ccd25117e040c194 316 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 193 6.9E-40 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A4R43_27900 08b10ae625b72039ccd25117e040c194 316 SMART SM00959 269 311 0.0041 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A4R43_27900 08b10ae625b72039ccd25117e040c194 316 PIRSF PIRSF006493 1 315 8.0E-95 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_27900 08b10ae625b72039ccd25117e040c194 316 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 258 2.3E-87 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_27900 08b10ae625b72039ccd25117e040c194 316 Gene3D G3DSA:2.40.290.10 5 180 3.5E-20 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily A4R43_27900 08b10ae625b72039ccd25117e040c194 316 SMART SM00559 53 183 6.6E-35 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A4R43_16915 695109e1818ccb81f086ca77de56a143 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 116 3.3E-14 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_16915 695109e1818ccb81f086ca77de56a143 226 SUPERFAMILY SSF161098 9 207 5.1E-35 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_16915 695109e1818ccb81f086ca77de56a143 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 222 6.1E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_16915 695109e1818ccb81f086ca77de56a143 226 Gene3D G3DSA:1.10.3720.10 6 224 1.7E-37 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_14440 d6d9f6f62be1921c96ad87354d1324e2 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 281 3.3E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_14440 d6d9f6f62be1921c96ad87354d1324e2 293 SUPERFAMILY SSF161098 13 293 8.11E-70 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_14440 d6d9f6f62be1921c96ad87354d1324e2 293 Gene3D G3DSA:1.10.3720.10 10 281 1.9E-63 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_20470 6548784e116cdaf85043473ef4eee3f0 481 Pfam PF04228 Putative neutral zinc metallopeptidase 67 263 4.4E-9 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative A4R43_20470 6548784e116cdaf85043473ef4eee3f0 481 SUPERFAMILY SSF55486 80 207 1.61E-7 T 14-10-2018 A4R43_36115 aaed84f0e61a365e6b7e51ca7b3031a1 262 Pfam PF13628 Domain of unknown function (DUF4142) 48 180 3.0E-18 T 14-10-2018 IPR025419 Domain of unknown function DUF4142 A4R43_29420 127a45ed33a77c263eae9b6b47ce8b3f 151 Pfam PF00011 Hsp20/alpha crystallin family 51 149 6.6E-24 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4R43_29420 127a45ed33a77c263eae9b6b47ce8b3f 151 Gene3D G3DSA:2.60.40.790 8 149 7.5E-37 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_29420 127a45ed33a77c263eae9b6b47ce8b3f 151 SUPERFAMILY SSF49764 15 148 5.58E-34 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_33395 72fd82e25165a9d6b980a1a5674bf75b 288 SUPERFAMILY SSF53474 13 282 8.11E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_33395 72fd82e25165a9d6b980a1a5674bf75b 288 Gene3D G3DSA:3.40.50.1820 9 284 2.4E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_33395 72fd82e25165a9d6b980a1a5674bf75b 288 Pfam PF00561 alpha/beta hydrolase fold 30 149 3.4E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22765 ad87eea3ab9185e92823380ae707c136 419 Gene3D G3DSA:1.20.1250.20 4 391 4.1E-34 T 14-10-2018 A4R43_22765 ad87eea3ab9185e92823380ae707c136 419 Pfam PF07690 Major Facilitator Superfamily 25 354 8.8E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_22765 ad87eea3ab9185e92823380ae707c136 419 SUPERFAMILY SSF103473 5 390 1.7E-39 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_35865 d695c750d2abfc8fd9328e85e0a2bd4a 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 6.7E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35865 d695c750d2abfc8fd9328e85e0a2bd4a 210 Gene3D G3DSA:1.10.357.10 8 203 7.3E-49 T 14-10-2018 A4R43_35865 d695c750d2abfc8fd9328e85e0a2bd4a 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 5.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35865 d695c750d2abfc8fd9328e85e0a2bd4a 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 5.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35865 d695c750d2abfc8fd9328e85e0a2bd4a 210 SUPERFAMILY SSF46689 12 92 2.21E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35865 d695c750d2abfc8fd9328e85e0a2bd4a 210 SUPERFAMILY SSF48498 90 201 2.48E-22 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_36905 d4d2dc230137da9f4f15f7214028ca0c 485 Gene3D G3DSA:3.30.420.40 2 236 2.6E-56 T 14-10-2018 A4R43_36905 d4d2dc230137da9f4f15f7214028ca0c 485 SUPERFAMILY SSF53067 5 248 3.14E-47 T 14-10-2018 A4R43_36905 d4d2dc230137da9f4f15f7214028ca0c 485 PIRSF PIRSF000538 3 485 2.0E-83 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4R43_36905 d4d2dc230137da9f4f15f7214028ca0c 485 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 245 1.7E-38 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4R43_36905 d4d2dc230137da9f4f15f7214028ca0c 485 Gene3D G3DSA:3.30.420.40 238 485 1.2E-48 T 14-10-2018 A4R43_36905 d4d2dc230137da9f4f15f7214028ca0c 485 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 300 436 4.6E-22 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4R43_36905 d4d2dc230137da9f4f15f7214028ca0c 485 SUPERFAMILY SSF53067 247 478 3.89E-39 T 14-10-2018 A4R43_04995 941691489b613230efa80f84448897ea 195 SUPERFAMILY SSF54534 60 190 7.07E-24 T 14-10-2018 A4R43_04995 941691489b613230efa80f84448897ea 195 Gene3D G3DSA:3.10.50.40 81 191 4.9E-28 T 14-10-2018 A4R43_04995 941691489b613230efa80f84448897ea 195 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 100 186 1.4E-18 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A4R43_05340 fbb227ecf1203087855a68d7e8378c99 407 Gene3D G3DSA:1.20.140.10 248 405 5.3E-37 T 14-10-2018 A4R43_05340 fbb227ecf1203087855a68d7e8378c99 407 SUPERFAMILY SSF47203 245 402 2.58E-41 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_05340 fbb227ecf1203087855a68d7e8378c99 407 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 129 9.4E-13 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_05340 fbb227ecf1203087855a68d7e8378c99 407 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 397 2.9E-33 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_05340 fbb227ecf1203087855a68d7e8378c99 407 Gene3D G3DSA:1.10.540.10 1 131 3.4E-48 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_05340 fbb227ecf1203087855a68d7e8378c99 407 SUPERFAMILY SSF56645 2 260 1.83E-64 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_05340 fbb227ecf1203087855a68d7e8378c99 407 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 235 2.8E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_05340 fbb227ecf1203087855a68d7e8378c99 407 Gene3D G3DSA:2.40.110.10 132 247 1.0E-49 T 14-10-2018 A4R43_39185 4e2b12d2e2ce6e60896dbd47e5526235 551 TIGRFAM TIGR01499 folC: bifunctional protein FolC 128 545 1.6E-106 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A4R43_39185 4e2b12d2e2ce6e60896dbd47e5526235 551 Gene3D G3DSA:3.40.1190.10 105 404 3.1E-96 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_39185 4e2b12d2e2ce6e60896dbd47e5526235 551 Pfam PF08245 Mur ligase middle domain 150 377 1.1E-13 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4R43_39185 4e2b12d2e2ce6e60896dbd47e5526235 551 Gene3D G3DSA:3.90.190.20 405 551 4.6E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_39185 4e2b12d2e2ce6e60896dbd47e5526235 551 SUPERFAMILY SSF53244 405 548 9.16E-26 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_39185 4e2b12d2e2ce6e60896dbd47e5526235 551 SUPERFAMILY SSF53623 111 397 1.32E-89 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_39185 4e2b12d2e2ce6e60896dbd47e5526235 551 Pfam PF02875 Mur ligase family, glutamate ligase domain 404 480 1.0E-11 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4R43_37455 75932ada7ba5295234fc76eb2364e798 158 SUPERFAMILY SSF51182 7 143 7.98E-26 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_37455 75932ada7ba5295234fc76eb2364e798 158 Gene3D G3DSA:2.60.120.10 2 156 7.2E-28 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_37455 75932ada7ba5295234fc76eb2364e798 158 SMART SM00835 3 153 0.0024 T 14-10-2018 IPR006045 Cupin 1 GO:0045735 A4R43_37455 75932ada7ba5295234fc76eb2364e798 158 Pfam PF07883 Cupin domain 42 109 3.9E-17 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_34065 8b37756a528b2f4774e4097661c1950e 105 SUPERFAMILY SSF140453 7 97 1.7E-15 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_34065 8b37756a528b2f4774e4097661c1950e 105 Pfam PF06013 Proteins of 100 residues with WXG 9 90 2.3E-13 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_34065 8b37756a528b2f4774e4097661c1950e 105 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 9 92 9.1E-15 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_34065 8b37756a528b2f4774e4097661c1950e 105 Gene3D G3DSA:1.10.287.1060 7 105 7.6E-23 T 14-10-2018 A4R43_37915 84f881c220e8949b956b5f521cb5069f 530 Pfam PF00939 Sodium:sulfate symporter transmembrane region 45 519 8.6E-71 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4R43_37915 84f881c220e8949b956b5f521cb5069f 530 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 474 490 - T 14-10-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 A4R43_37915 84f881c220e8949b956b5f521cb5069f 530 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 62 519 2.9E-80 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4R43_03355 143003f7a83a5456dfe43e72a46203f8 244 Gene3D G3DSA:3.30.450.40 9 178 7.7E-12 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_03355 143003f7a83a5456dfe43e72a46203f8 244 PIRSF PIRSF036625 1 241 1.2E-50 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4R43_03355 143003f7a83a5456dfe43e72a46203f8 244 SUPERFAMILY SSF52172 156 230 2.48E-12 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_03355 143003f7a83a5456dfe43e72a46203f8 244 Gene3D G3DSA:1.10.10.10 179 237 1.0E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03355 143003f7a83a5456dfe43e72a46203f8 244 SUPERFAMILY SSF55781 23 177 5.49E-12 T 14-10-2018 A4R43_03355 143003f7a83a5456dfe43e72a46203f8 244 SMART SM01012 176 231 4.6E-23 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_03355 143003f7a83a5456dfe43e72a46203f8 244 Pfam PF03861 ANTAR domain 179 229 2.2E-21 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_37510 989e503da8600836188225cddac3c8f8 319 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 1.7E-60 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A4R43_37510 989e503da8600836188225cddac3c8f8 319 Gene3D G3DSA:3.40.50.300 4 201 6.2E-42 T 14-10-2018 A4R43_37510 989e503da8600836188225cddac3c8f8 319 SUPERFAMILY SSF52540 13 284 6.89E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37510 989e503da8600836188225cddac3c8f8 319 PIRSF PIRSF002849 2 314 3.6E-122 T 14-10-2018 A4R43_37510 989e503da8600836188225cddac3c8f8 319 Gene3D G3DSA:1.10.8.300 202 309 6.0E-29 T 14-10-2018 A4R43_26170 ec29784894a9f8df81a6af6ef537c01b 254 SUPERFAMILY SSF110399 6 244 1.57E-82 T 14-10-2018 A4R43_26170 ec29784894a9f8df81a6af6ef537c01b 254 Hamap MF_00443 Thiazole synthase [thiG]. 7 254 40.416 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A4R43_26170 ec29784894a9f8df81a6af6ef537c01b 254 Pfam PF05690 Thiazole biosynthesis protein ThiG 10 252 7.9E-105 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A4R43_26170 ec29784894a9f8df81a6af6ef537c01b 254 Gene3D G3DSA:3.20.20.70 1 254 4.6E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_36415 00455bb39a2500aa36a944d69b7fb4db 321 Pfam PF01183 Glycosyl hydrolases family 25 7 185 2.8E-19 T 14-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 A4R43_36415 00455bb39a2500aa36a944d69b7fb4db 321 SMART SM00641 3 107 0.0011 T 14-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup A4R43_36415 00455bb39a2500aa36a944d69b7fb4db 321 SUPERFAMILY SSF51445 4 207 3.79E-33 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_36415 00455bb39a2500aa36a944d69b7fb4db 321 Gene3D G3DSA:3.20.20.80 1 207 6.9E-36 T 14-10-2018 A4R43_03560 e5f26d4ba72af640f40ac1b240ef2024 152 Gene3D G3DSA:3.10.180.10 3 152 4.6E-56 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_03560 e5f26d4ba72af640f40ac1b240ef2024 152 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 147 2.1E-12 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_03560 e5f26d4ba72af640f40ac1b240ef2024 152 SUPERFAMILY SSF54593 9 149 1.09E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_25890 15ccbdb0119b04fa469cc1582fcd5248 272 Pfam PF00149 Calcineurin-like phosphoesterase 11 224 3.2E-12 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_25890 15ccbdb0119b04fa469cc1582fcd5248 272 Gene3D G3DSA:3.60.21.10 3 259 7.6E-51 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_25890 15ccbdb0119b04fa469cc1582fcd5248 272 SUPERFAMILY SSF56300 10 255 2.31E-36 T 14-10-2018 A4R43_37200 194d6edf8f82f4b4e600b6e62fa231e2 153 Gene3D G3DSA:3.30.530.20 1 153 1.1E-38 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_37200 194d6edf8f82f4b4e600b6e62fa231e2 153 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 149 1.2E-28 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_37200 194d6edf8f82f4b4e600b6e62fa231e2 153 SUPERFAMILY SSF55961 7 151 4.84E-36 T 14-10-2018 A4R43_06550 ad28457a004ea57a4004340c3115bdd3 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06550 ad28457a004ea57a4004340c3115bdd3 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06550 ad28457a004ea57a4004340c3115bdd3 214 Gene3D G3DSA:1.10.357.10 3 203 6.0E-38 T 14-10-2018 A4R43_06550 ad28457a004ea57a4004340c3115bdd3 214 SUPERFAMILY SSF46689 5 75 4.69E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_06550 ad28457a004ea57a4004340c3115bdd3 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 3.9E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00330 8f7d5d9de255cce0cbf952d2790cb418 315 Pfam PF00682 HMGL-like 9 288 3.6E-38 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4R43_00330 8f7d5d9de255cce0cbf952d2790cb418 315 Gene3D G3DSA:3.20.20.70 4 309 1.5E-99 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_00330 8f7d5d9de255cce0cbf952d2790cb418 315 SUPERFAMILY SSF51569 6 306 6.45E-60 T 14-10-2018 A4R43_23165 c750eef0ab11d7abdced82307862a23d 334 Pfam PF03193 RsgA GTPase 99 266 3.1E-41 T 14-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 A4R43_23165 c750eef0ab11d7abdced82307862a23d 334 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 73 325 3.1E-41 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A4R43_23165 c750eef0ab11d7abdced82307862a23d 334 SUPERFAMILY SSF52540 116 322 1.86E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23165 c750eef0ab11d7abdced82307862a23d 334 Gene3D G3DSA:3.40.50.300 101 266 5.0E-39 T 14-10-2018 A4R43_25140 705343f1400005de013d9de6d7c206d0 101 SUPERFAMILY SSF46785 17 89 5.08E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_25140 705343f1400005de013d9de6d7c206d0 101 Pfam PF13601 Winged helix DNA-binding domain 17 94 8.1E-22 T 14-10-2018 IPR027395 Winged helix DNA-binding domain A4R43_25140 705343f1400005de013d9de6d7c206d0 101 Gene3D G3DSA:1.10.10.10 6 100 6.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28470 24bd27fc576db841aada69af0af90884 887 Pfam PF13604 AAA domain 142 252 2.8E-6 T 14-10-2018 A4R43_28470 24bd27fc576db841aada69af0af90884 887 SUPERFAMILY SSF56024 742 836 7.85E-10 T 14-10-2018 A4R43_28470 24bd27fc576db841aada69af0af90884 887 SUPERFAMILY SSF52540 138 215 3.29E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28470 24bd27fc576db841aada69af0af90884 887 Gene3D G3DSA:3.30.870.10 726 858 1.7E-8 T 14-10-2018 A4R43_26935 89a118f524088384d528687ef64d0520 406 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 9 109 3.5E-7 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 A4R43_26935 89a118f524088384d528687ef64d0520 406 Pfam PF07804 HipA-like C-terminal domain 137 374 1.3E-43 T 14-10-2018 IPR012893 HipA-like, C-terminal A4R43_26935 89a118f524088384d528687ef64d0520 406 Pfam PF13657 HipA N-terminal domain 10 109 5.8E-15 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 Gene3D G3DSA:3.40.50.300 158 339 1.1E-68 T 14-10-2018 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 Gene3D G3DSA:1.20.58.760 421 622 2.9E-69 T 14-10-2018 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 211 230 9.4E-5 T 14-10-2018 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 501 520 9.4E-5 T 14-10-2018 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 120 610 2.3E-226 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 Pfam PF01434 Peptidase family M41 402 609 1.1E-77 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 338 4.2E-45 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 SUPERFAMILY SSF52540 163 410 2.67E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 SUPERFAMILY SSF140990 421 614 9.42E-68 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 SMART SM00382 203 342 3.1E-25 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 646 36.085 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A4R43_26820 7545243fdb2c27bec26547a220d4a316 797 Gene3D G3DSA:1.10.8.60 341 418 5.3E-24 T 14-10-2018 A4R43_29695 c2ac27e8c31ed9f755d822ec13ada03b 988 Pfam PF00486 Transcriptional regulatory protein, C terminal 753 811 2.3E-4 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_29695 c2ac27e8c31ed9f755d822ec13ada03b 988 Gene3D G3DSA:3.10.350.10 190 240 7.4E-6 T 14-10-2018 IPR036779 LysM domain superfamily A4R43_29695 c2ac27e8c31ed9f755d822ec13ada03b 988 Pfam PF03704 Bacterial transcriptional activator domain 851 967 1.1E-6 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_29695 c2ac27e8c31ed9f755d822ec13ada03b 988 SMART SM00862 748 827 1.0E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_29695 c2ac27e8c31ed9f755d822ec13ada03b 988 Gene3D G3DSA:1.10.10.10 722 828 2.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29695 c2ac27e8c31ed9f755d822ec13ada03b 988 SMART SM01043 834 971 6.3E-8 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_29695 c2ac27e8c31ed9f755d822ec13ada03b 988 SUPERFAMILY SSF46894 735 812 9.35E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 SUPERFAMILY SSF51735 329 513 3.4E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 515 595 6.3E-12 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 Gene3D G3DSA:3.40.50.720 323 516 5.0E-60 T 14-10-2018 A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 Gene3D G3DSA:3.90.226.10 20 322 4.5E-53 T 14-10-2018 A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 SUPERFAMILY SSF48179 513 613 2.72E-15 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 SUPERFAMILY SSF52096 28 319 6.09E-41 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 Gene3D G3DSA:1.10.1040.50 517 689 1.7E-33 T 14-10-2018 A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 SUPERFAMILY SSF48179 626 686 8.5E-11 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 Pfam PF00378 Enoyl-CoA hydratase/isomerase 70 228 5.8E-24 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_13895 f8017338653490f7a3d33045f2e1b2cf 702 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 332 511 4.7E-56 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_34015 14c9db00f19c25371dca6c7fa6a62fb8 402 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 207 309 9.2E-22 T 14-10-2018 IPR021368 Type VII secretion system protein EccE A4R43_34015 14c9db00f19c25371dca6c7fa6a62fb8 402 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 9 400 6.9E-52 T 14-10-2018 IPR021368 Type VII secretion system protein EccE A4R43_35180 33812ddfcf7514c2cef74537bdb9d64f 400 Gene3D G3DSA:3.50.50.60 6 342 4.8E-61 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35180 33812ddfcf7514c2cef74537bdb9d64f 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.9E-9 T 14-10-2018 A4R43_35180 33812ddfcf7514c2cef74537bdb9d64f 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.9E-9 T 14-10-2018 A4R43_35180 33812ddfcf7514c2cef74537bdb9d64f 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 2.9E-9 T 14-10-2018 A4R43_35180 33812ddfcf7514c2cef74537bdb9d64f 400 Pfam PF01494 FAD binding domain 3 319 2.3E-10 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_35180 33812ddfcf7514c2cef74537bdb9d64f 400 Gene3D G3DSA:3.30.9.50 39 273 4.8E-61 T 14-10-2018 A4R43_35180 33812ddfcf7514c2cef74537bdb9d64f 400 SUPERFAMILY SSF51905 2 377 9.72E-47 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_05820 c2cd8198f221944fb21703cf4fedbc77 318 Pfam PF03741 Integral membrane protein TerC family 69 272 5.5E-52 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A4R43_05820 c2cd8198f221944fb21703cf4fedbc77 318 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 310 2.5E-114 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 A4R43_41160 d1deac4e022a29d058d8f97bf39a0c99 457 Pfam PF05193 Peptidase M16 inactive domain 192 369 2.9E-42 T 14-10-2018 IPR007863 Peptidase M16, C-terminal A4R43_41160 d1deac4e022a29d058d8f97bf39a0c99 457 Gene3D G3DSA:3.30.830.10 27 242 2.8E-68 T 14-10-2018 A4R43_41160 d1deac4e022a29d058d8f97bf39a0c99 457 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 58 81 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 A4R43_41160 d1deac4e022a29d058d8f97bf39a0c99 457 Gene3D G3DSA:3.30.830.10 246 454 1.3E-53 T 14-10-2018 A4R43_41160 d1deac4e022a29d058d8f97bf39a0c99 457 SUPERFAMILY SSF63411 27 230 3.48E-57 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4R43_41160 d1deac4e022a29d058d8f97bf39a0c99 457 SUPERFAMILY SSF63411 253 443 7.67E-46 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4R43_41160 d1deac4e022a29d058d8f97bf39a0c99 457 Pfam PF00675 Insulinase (Peptidase family M16) 37 184 3.3E-38 T 14-10-2018 IPR011765 Peptidase M16, N-terminal A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 SUPERFAMILY SSF53383 103 460 9.82E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 Gene3D G3DSA:1.10.10.10 17 89 3.8E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 83 2.7E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 Gene3D G3DSA:3.40.640.10 99 456 1.4E-104 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 SMART SM00345 24 83 6.3E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 SUPERFAMILY SSF46785 25 87 2.92E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 5.4E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 5.4E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23550 3d5d87c64659774edb4df5596e3cc857 463 Pfam PF00155 Aminotransferase class I and II 121 427 4.0E-20 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_26085 05767adb65a9474bf646a31a801a5dcc 197 Pfam PF01987 Mitochondrial biogenesis AIM24 10 194 1.7E-23 T 14-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A4R43_26085 05767adb65a9474bf646a31a801a5dcc 197 Gene3D G3DSA:3.60.160.10 1 197 2.2E-26 T 14-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily A4R43_26085 05767adb65a9474bf646a31a801a5dcc 197 SUPERFAMILY SSF51219 1 195 1.46E-29 T 14-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A4R43_35205 e47c09321a1bc2236e5d05f0bd9ecc0c 200 Gene3D G3DSA:3.10.180.10 2 122 2.4E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_35205 e47c09321a1bc2236e5d05f0bd9ecc0c 200 SUPERFAMILY SSF54593 2 156 2.51E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_40745 ed367e45cc079099659e60f7a46d061e 150 Gene3D G3DSA:3.30.420.10 2 148 2.5E-58 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_40745 ed367e45cc079099659e60f7a46d061e 150 SUPERFAMILY SSF53098 5 144 5.69E-57 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_40745 ed367e45cc079099659e60f7a46d061e 150 Pfam PF00075 RNase H 6 143 5.9E-51 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A4R43_40745 ed367e45cc079099659e60f7a46d061e 150 Hamap MF_00042 Ribonuclease H [rnhA]. 3 150 33.729 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 A4R43_15755 e6de1e0388ed2d0b65a43539487ca4d9 389 Gene3D G3DSA:1.10.10.10 2 78 7.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15755 e6de1e0388ed2d0b65a43539487ca4d9 389 Pfam PF00480 ROK family 87 381 5.2E-46 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_15755 e6de1e0388ed2d0b65a43539487ca4d9 389 Gene3D G3DSA:3.30.420.40 207 368 2.1E-64 T 14-10-2018 A4R43_15755 e6de1e0388ed2d0b65a43539487ca4d9 389 SUPERFAMILY SSF46785 12 76 4.49E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15755 e6de1e0388ed2d0b65a43539487ca4d9 389 SUPERFAMILY SSF53067 86 384 1.46E-41 T 14-10-2018 A4R43_15755 e6de1e0388ed2d0b65a43539487ca4d9 389 Gene3D G3DSA:3.30.420.40 92 378 2.1E-64 T 14-10-2018 A4R43_25405 444852be7dde0fde120147c21356124f 229 Gene3D G3DSA:1.10.10.60 2 49 3.4E-16 T 14-10-2018 A4R43_25405 444852be7dde0fde120147c21356124f 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 51 1.3E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25405 444852be7dde0fde120147c21356124f 229 Gene3D G3DSA:1.10.357.10 50 186 1.8E-39 T 14-10-2018 A4R43_25405 444852be7dde0fde120147c21356124f 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.5E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25405 444852be7dde0fde120147c21356124f 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.5E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25405 444852be7dde0fde120147c21356124f 229 SUPERFAMILY SSF48498 74 186 1.49E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_25405 444852be7dde0fde120147c21356124f 229 SUPERFAMILY SSF46689 5 79 3.54E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_15105 1fa7a11b82bf5862927130b35483fa2d 365 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 293 310 5.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_15105 1fa7a11b82bf5862927130b35483fa2d 365 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 29 43 5.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_15105 1fa7a11b82bf5862927130b35483fa2d 365 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 312 330 5.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_15105 1fa7a11b82bf5862927130b35483fa2d 365 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 335 355 5.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_15105 1fa7a11b82bf5862927130b35483fa2d 365 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 95 115 5.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_15105 1fa7a11b82bf5862927130b35483fa2d 365 SUPERFAMILY SSF53335 9 355 6.25E-61 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_15105 1fa7a11b82bf5862927130b35483fa2d 365 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 34 39 - T 14-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 A4R43_15105 1fa7a11b82bf5862927130b35483fa2d 365 Pfam PF01555 DNA methylase 30 349 1.8E-51 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4R43_03465 c4f038aed3fbfc7bfe2ff9aa6324e55f 260 Gene3D G3DSA:3.20.20.150 2 260 1.2E-61 T 14-10-2018 A4R43_03465 c4f038aed3fbfc7bfe2ff9aa6324e55f 260 Pfam PF01261 Xylose isomerase-like TIM barrel 25 222 1.4E-26 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_03465 c4f038aed3fbfc7bfe2ff9aa6324e55f 260 PIRSF PIRSF006241 3 260 1.2E-63 T 14-10-2018 IPR026040 Hydroxypyruvate isomerase-like A4R43_03465 c4f038aed3fbfc7bfe2ff9aa6324e55f 260 SUPERFAMILY SSF51658 8 259 9.7E-60 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_19265 f4f7fe716ef968753afe1d3c931a58c4 353 Gene3D G3DSA:3.50.50.60 2 353 2.3E-108 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_19265 f4f7fe716ef968753afe1d3c931a58c4 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.2E-8 T 14-10-2018 A4R43_19265 f4f7fe716ef968753afe1d3c931a58c4 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 4.2E-8 T 14-10-2018 A4R43_19265 f4f7fe716ef968753afe1d3c931a58c4 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.3E-16 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_19265 f4f7fe716ef968753afe1d3c931a58c4 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 138 1.3E-16 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_19265 f4f7fe716ef968753afe1d3c931a58c4 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 1.3E-16 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_19265 f4f7fe716ef968753afe1d3c931a58c4 353 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 11 208 1.0E-21 T 14-10-2018 A4R43_19265 f4f7fe716ef968753afe1d3c931a58c4 353 SUPERFAMILY SSF51905 4 350 1.11E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_14455 a432170266e5928578cc3cdb2d2202d5 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 156 1.6E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_14455 a432170266e5928578cc3cdb2d2202d5 167 SUPERFAMILY SSF88659 82 157 3.36E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_14455 a432170266e5928578cc3cdb2d2202d5 167 SUPERFAMILY SSF88946 4 69 4.71E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_14455 a432170266e5928578cc3cdb2d2202d5 167 Pfam PF08281 Sigma-70, region 4 102 153 7.4E-17 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_14455 a432170266e5928578cc3cdb2d2202d5 167 Gene3D G3DSA:1.10.1740.10 2 77 3.5E-10 T 14-10-2018 A4R43_14455 a432170266e5928578cc3cdb2d2202d5 167 Pfam PF04542 Sigma-70 region 2 12 74 3.1E-6 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_14455 a432170266e5928578cc3cdb2d2202d5 167 Gene3D G3DSA:1.10.10.10 88 160 2.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25610 30182cca8bc5e770cae917de0ad85be7 236 PIRSF PIRSF005624 30 235 1.6E-44 T 14-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 A4R43_25610 30182cca8bc5e770cae917de0ad85be7 236 Hamap MF_01389 Urease accessory protein UreG [ureG]. 36 234 41.92 T 14-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 A4R43_25610 30182cca8bc5e770cae917de0ad85be7 236 Gene3D G3DSA:3.40.50.300 38 231 3.4E-45 T 14-10-2018 A4R43_25610 30182cca8bc5e770cae917de0ad85be7 236 SUPERFAMILY SSF52540 32 234 3.79E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25610 30182cca8bc5e770cae917de0ad85be7 236 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 39 231 2.6E-78 T 14-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 A4R43_25610 30182cca8bc5e770cae917de0ad85be7 236 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 40 210 9.6E-34 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4R43_09490 a49d3c0a8b5ef2cea82eeb826283aafc 413 Pfam PF12006 Protein of unknown function (DUF3500) 77 401 9.8E-86 T 14-10-2018 IPR021889 Protein of unknown function DUF3500 A4R43_39950 263267a12f787dff381d1148d8c20995 144 SUPERFAMILY SSF159888 45 114 2.62E-12 T 14-10-2018 A4R43_39950 263267a12f787dff381d1148d8c20995 144 Pfam PF08818 Domain of unknown function (DU1801) 53 143 7.3E-9 T 14-10-2018 IPR014922 Domain of unknown function DUF1801 A4R43_39950 263267a12f787dff381d1148d8c20995 144 Gene3D G3DSA:1.10.10.810 33 110 9.0E-6 T 14-10-2018 A4R43_17445 c6cc68a30d1cd2447cb2fb846b7126ce 199 SUPERFAMILY SSF54211 88 184 3.9E-28 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_17445 c6cc68a30d1cd2447cb2fb846b7126ce 199 Gene3D G3DSA:3.30.230.40 91 199 3.3E-35 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A4R43_17445 c6cc68a30d1cd2447cb2fb846b7126ce 199 SUPERFAMILY SSF54211 3 87 7.84E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_17445 c6cc68a30d1cd2447cb2fb846b7126ce 199 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 199 41.119 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4R43_17445 c6cc68a30d1cd2447cb2fb846b7126ce 199 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 179 1.6E-59 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4R43_17445 c6cc68a30d1cd2447cb2fb846b7126ce 199 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4R43_17445 c6cc68a30d1cd2447cb2fb846b7126ce 199 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 161 173 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4R43_17445 c6cc68a30d1cd2447cb2fb846b7126ce 199 Gene3D G3DSA:3.30.230.40 1 90 3.2E-37 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A4R43_09835 ab8a7fe8ead3f1decb1d2326ea865d24 395 PRINTS PR00412 Epoxide hydrolase signature 101 119 2.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_09835 ab8a7fe8ead3f1decb1d2326ea865d24 395 PRINTS PR00412 Epoxide hydrolase signature 355 377 2.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_09835 ab8a7fe8ead3f1decb1d2326ea865d24 395 PRINTS PR00412 Epoxide hydrolase signature 130 145 2.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_09835 ab8a7fe8ead3f1decb1d2326ea865d24 395 PIRSF PIRSF001112 1 384 4.4E-110 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_09835 ab8a7fe8ead3f1decb1d2326ea865d24 395 SUPERFAMILY SSF53474 3 381 1.34E-93 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09835 ab8a7fe8ead3f1decb1d2326ea865d24 395 Gene3D G3DSA:3.40.50.1820 5 389 6.3E-138 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09835 ab8a7fe8ead3f1decb1d2326ea865d24 395 Pfam PF06441 Epoxide hydrolase N terminus 5 110 2.2E-35 T 14-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 A4R43_35915 09457fe9073fe7d642c71cc11f963eef 371 Gene3D G3DSA:1.10.10.10 275 368 2.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35915 09457fe9073fe7d642c71cc11f963eef 371 Gene3D G3DSA:3.40.50.10090 14 261 8.4E-66 T 14-10-2018 A4R43_35915 09457fe9073fe7d642c71cc11f963eef 371 Pfam PF00486 Transcriptional regulatory protein, C terminal 298 363 1.7E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_35915 09457fe9073fe7d642c71cc11f963eef 371 Pfam PF02602 Uroporphyrinogen-III synthase HemD 22 262 7.3E-39 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_35915 09457fe9073fe7d642c71cc11f963eef 371 SUPERFAMILY SSF46894 276 365 3.12E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_35915 09457fe9073fe7d642c71cc11f963eef 371 SMART SM00862 294 363 2.5E-14 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_35915 09457fe9073fe7d642c71cc11f963eef 371 Gene3D G3DSA:3.40.50.10090 40 178 8.4E-66 T 14-10-2018 A4R43_35915 09457fe9073fe7d642c71cc11f963eef 371 SUPERFAMILY SSF69618 9 264 7.19E-54 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_05330 7571fa8494e773b56b7331c8cf8a00d2 360 SUPERFAMILY SSF47203 213 353 8.54E-36 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_05330 7571fa8494e773b56b7331c8cf8a00d2 360 SUPERFAMILY SSF56645 3 188 8.6E-20 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_05330 7571fa8494e773b56b7331c8cf8a00d2 360 Gene3D G3DSA:1.20.140.10 218 357 1.9E-36 T 14-10-2018 A4R43_05330 7571fa8494e773b56b7331c8cf8a00d2 360 Gene3D G3DSA:1.10.540.10 4 119 5.5E-24 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_05330 7571fa8494e773b56b7331c8cf8a00d2 360 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 213 353 6.2E-27 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_05330 7571fa8494e773b56b7331c8cf8a00d2 360 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 108 2.3E-14 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_03885 49d557dcab302447264f86acf73f4364 215 SMART SM00421 152 209 4.5E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03885 49d557dcab302447264f86acf73f4364 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03885 49d557dcab302447264f86acf73f4364 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 4.7E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03885 49d557dcab302447264f86acf73f4364 215 SUPERFAMILY SSF52172 2 133 5.98E-34 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_03885 49d557dcab302447264f86acf73f4364 215 SUPERFAMILY SSF46894 139 212 6.12E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_03885 49d557dcab302447264f86acf73f4364 215 Pfam PF00072 Response regulator receiver domain 4 116 8.4E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_03885 49d557dcab302447264f86acf73f4364 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03885 49d557dcab302447264f86acf73f4364 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03885 49d557dcab302447264f86acf73f4364 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03885 49d557dcab302447264f86acf73f4364 215 SMART SM00448 2 115 2.1E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_03885 49d557dcab302447264f86acf73f4364 215 Gene3D G3DSA:3.40.50.12740 2 213 2.0E-66 T 14-10-2018 A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 108 6.0E-15 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 130 3.4E-27 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 53 2.2E-18 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 Gene3D G3DSA:1.20.5.710 4 58 8.6E-20 T 14-10-2018 A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 130 24.312 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 130 4.6E-47 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 Gene3D G3DSA:3.30.1390.10 59 130 1.4E-27 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 SUPERFAMILY SSF54736 58 130 1.33E-21 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4R43_33590 f018e5b775faace0182e5575b5a187ac 130 SUPERFAMILY SSF48300 5 65 6.93E-15 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_16880 3b05f919ece330569d97e87fb1345a19 115 SUPERFAMILY SSF50118 1 115 8.5E-29 T 14-10-2018 A4R43_16880 3b05f919ece330569d97e87fb1345a19 115 PIRSF PIRSF033490 1 115 2.1E-35 T 14-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A4R43_16880 3b05f919ece330569d97e87fb1345a19 115 Gene3D G3DSA:2.30.30.110 1 115 4.7E-32 T 14-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4R43_16880 3b05f919ece330569d97e87fb1345a19 115 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 112 3.4E-24 T 14-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A4R43_08085 c2584f75616e7bf8ac2d749861ca1f01 202 SUPERFAMILY SSF46689 14 83 1.8E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08085 c2584f75616e7bf8ac2d749861ca1f01 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 66 1.9E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08085 c2584f75616e7bf8ac2d749861ca1f01 202 Gene3D G3DSA:1.10.357.10 11 199 3.0E-39 T 14-10-2018 A4R43_21565 e01d1aec56a985298ec38a47a83cdbfd 212 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 A4R43_21565 e01d1aec56a985298ec38a47a83cdbfd 212 Gene3D G3DSA:3.40.50.1240 2 207 1.4E-59 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_21565 e01d1aec56a985298ec38a47a83cdbfd 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 193 3.1E-57 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_21565 e01d1aec56a985298ec38a47a83cdbfd 212 PIRSF PIRSF000709 2 122 1.6E-8 T 14-10-2018 A4R43_21565 e01d1aec56a985298ec38a47a83cdbfd 212 SMART SM00855 4 154 6.5E-16 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_21565 e01d1aec56a985298ec38a47a83cdbfd 212 SUPERFAMILY SSF53254 1 205 5.07E-57 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_12225 5ad03ceeba4b6127d2a80c5ca9e8f5ab 225 SMART SM00421 157 214 3.6E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12225 5ad03ceeba4b6127d2a80c5ca9e8f5ab 225 SUPERFAMILY SSF46894 148 220 8.84E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_12225 5ad03ceeba4b6127d2a80c5ca9e8f5ab 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.0E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12225 5ad03ceeba4b6127d2a80c5ca9e8f5ab 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.0E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12225 5ad03ceeba4b6127d2a80c5ca9e8f5ab 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.0E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12225 5ad03ceeba4b6127d2a80c5ca9e8f5ab 225 Gene3D G3DSA:1.10.10.10 105 225 1.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12225 5ad03ceeba4b6127d2a80c5ca9e8f5ab 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 210 8.6E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38655 c6b08426136d7ea6bd8e1fe48854ebb5 143 SUPERFAMILY SSF55961 5 141 9.83E-33 T 14-10-2018 A4R43_38655 c6b08426136d7ea6bd8e1fe48854ebb5 143 Gene3D G3DSA:3.30.530.20 4 143 2.7E-36 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_38655 c6b08426136d7ea6bd8e1fe48854ebb5 143 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 140 3.4E-22 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 14-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 2.0E-50 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 281 31.522 T 14-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 SUPERFAMILY SSF54913 209 280 1.33E-21 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 Pfam PF08029 HisG, C-terminal domain 206 277 4.2E-26 T 14-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 Gene3D G3DSA:3.30.70.120 209 275 5.4E-29 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 SUPERFAMILY SSF53850 1 207 2.82E-61 T 14-10-2018 A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 Pfam PF01634 ATP phosphoribosyltransferase 49 202 2.2E-39 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 Gene3D G3DSA:3.40.190.10 2 184 2.9E-59 T 14-10-2018 A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 Gene3D G3DSA:3.40.190.10 91 178 2.9E-59 T 14-10-2018 A4R43_10860 a4eef76e44adfd79d8efe549ac3ac274 281 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 192 280 3.4E-29 T 14-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4R43_01205 6e18fad8673181d45533a4e73f708d1c 1639 Gene3D G3DSA:3.90.1720.10 1253 1331 5.9E-6 T 14-10-2018 A4R43_01205 6e18fad8673181d45533a4e73f708d1c 1639 SUPERFAMILY SSF54001 1276 1311 8.83E-6 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_01205 6e18fad8673181d45533a4e73f708d1c 1639 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 263 335 1.6E-19 T 14-10-2018 IPR013491 Caudovirus, tape measure, N-terminal A4R43_01205 6e18fad8673181d45533a4e73f708d1c 1639 Gene3D G3DSA:1.10.530.10 1466 1530 3.2E-8 T 14-10-2018 A4R43_30855 4fe2517ffc12b9fbcc4781a8d5c1230d 681 Pfam PF05787 Bacterial protein of unknown function (DUF839) 89 639 1.4E-161 T 14-10-2018 IPR008557 Protein of unknown function DUF839 A4R43_30855 4fe2517ffc12b9fbcc4781a8d5c1230d 681 SUPERFAMILY SSF63829 324 609 7.19E-9 T 14-10-2018 A4R43_25200 ec765ffcf9daca6b0f900fe4a7d01e57 211 Gene3D G3DSA:1.10.357.10 7 195 6.9E-37 T 14-10-2018 A4R43_25200 ec765ffcf9daca6b0f900fe4a7d01e57 211 SUPERFAMILY SSF46689 13 85 3.99E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25200 ec765ffcf9daca6b0f900fe4a7d01e57 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 2.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25200 ec765ffcf9daca6b0f900fe4a7d01e57 211 SUPERFAMILY SSF48498 86 187 1.33E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_22275 3f153298aa29866241ae2b342f937316 219 Gene3D G3DSA:2.70.180.20 1 90 1.5E-19 T 14-10-2018 A4R43_22275 3f153298aa29866241ae2b342f937316 219 Hamap MF_00722 Endonuclease NucS [nucS]. 1 211 32.152 T 14-10-2018 IPR002793 Endonuclease NucS GO:0004519 A4R43_22275 3f153298aa29866241ae2b342f937316 219 Gene3D G3DSA:3.40.1350.10 94 205 7.1E-26 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A4R43_22275 3f153298aa29866241ae2b342f937316 219 Pfam PF01939 Endonuclease NucS 1 219 9.7E-84 T 14-10-2018 IPR002793 Endonuclease NucS GO:0004519 A4R43_09025 dbbdb59f143baf50d23724ed9ce895f2 496 Pfam PF00854 POT family 93 458 2.3E-66 T 14-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 A4R43_09025 dbbdb59f143baf50d23724ed9ce895f2 496 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 12 482 2.1E-114 T 14-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 A4R43_09025 dbbdb59f143baf50d23724ed9ce895f2 496 SUPERFAMILY SSF103473 16 486 5.49E-28 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_09025 dbbdb59f143baf50d23724ed9ce895f2 496 Gene3D G3DSA:1.20.1250.20 3 492 1.9E-125 T 14-10-2018 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 Gene3D G3DSA:3.40.50.300 65 280 1.2E-39 T 14-10-2018 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 SUPERFAMILY SSF54211 255 448 4.17E-30 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 Gene3D G3DSA:3.30.230.10 292 433 1.0E-10 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 Hamap MF_01498 DNA repair protein RadA [radA]. 22 453 41.82 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 SUPERFAMILY SSF52540 70 293 3.47E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 SMART SM00382 87 244 3.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 Pfam PF13481 AAA domain 63 222 3.9E-16 T 14-10-2018 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 TIGRFAM TIGR00416 sms: DNA repair protein RadA 4 448 7.5E-155 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 PRINTS PR01874 DNA repair protein radA signature 79 107 5.8E-74 T 14-10-2018 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 PRINTS PR01874 DNA repair protein radA signature 213 241 5.8E-74 T 14-10-2018 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 PRINTS PR01874 DNA repair protein radA signature 322 345 5.8E-74 T 14-10-2018 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 PRINTS PR01874 DNA repair protein radA signature 11 35 5.8E-74 T 14-10-2018 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 PRINTS PR01874 DNA repair protein radA signature 174 198 5.8E-74 T 14-10-2018 A4R43_26565 fe6fba4ed7fc368a87c80cc629c4cf2c 457 PRINTS PR01874 DNA repair protein radA signature 248 274 5.8E-74 T 14-10-2018 A4R43_27405 7ab4dff35fbb0020ebc6887b33456a89 334 SUPERFAMILY SSF161098 91 318 3.53E-20 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_27405 7ab4dff35fbb0020ebc6887b33456a89 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 332 1.0E-37 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_35740 9367e6fefa56429d733de5d93ab859e0 371 Gene3D G3DSA:3.20.20.80 87 345 5.0E-22 T 14-10-2018 A4R43_35740 9367e6fefa56429d733de5d93ab859e0 371 SUPERFAMILY SSF51445 84 320 1.21E-13 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_23230 2f765d9aee7013523a44e429cf643246 225 SMART SM00448 3 113 2.6E-46 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_23230 2f765d9aee7013523a44e429cf643246 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 6.4E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_23230 2f765d9aee7013523a44e429cf643246 225 Gene3D G3DSA:1.10.10.10 126 225 3.3E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23230 2f765d9aee7013523a44e429cf643246 225 Gene3D G3DSA:3.40.50.2300 1 125 2.8E-39 T 14-10-2018 A4R43_23230 2f765d9aee7013523a44e429cf643246 225 SUPERFAMILY SSF52172 3 179 9.82E-45 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_23230 2f765d9aee7013523a44e429cf643246 225 Pfam PF00072 Response regulator receiver domain 5 114 1.3E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_23230 2f765d9aee7013523a44e429cf643246 225 SMART SM00862 146 222 1.1E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 Gene3D G3DSA:2.40.110.10 130 242 4.0E-34 T 14-10-2018 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 SUPERFAMILY SSF56645 14 249 1.96E-62 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 133 145 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 278 380 2.1E-4 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 SUPERFAMILY SSF47203 238 378 3.43E-5 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 Gene3D G3DSA:1.20.140.10 243 382 3.9E-11 T 14-10-2018 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 224 8.7E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 Gene3D G3DSA:1.10.540.10 4 128 1.2E-24 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_24365 11328c43b3b33329525f24d4e9487206 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 127 2.0E-21 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_18250 739b5c514f114c652215fb2fa0c2271b 220 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 139 216 3.1E-17 T 14-10-2018 IPR039561 Peptidase M15C GO:0008233 A4R43_18250 739b5c514f114c652215fb2fa0c2271b 220 Gene3D G3DSA:3.30.1380.10 77 216 1.7E-12 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_18250 739b5c514f114c652215fb2fa0c2271b 220 SUPERFAMILY SSF55166 64 217 2.04E-22 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_27425 676a258ade35339cc14cc12faa0de50d 121 Gene3D G3DSA:3.30.1310.10 3 110 5.7E-35 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_27425 676a258ade35339cc14cc12faa0de50d 121 SUPERFAMILY SSF82607 10 102 9.02E-28 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_27425 676a258ade35339cc14cc12faa0de50d 121 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 8 102 20.62 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_27425 676a258ade35339cc14cc12faa0de50d 121 Pfam PF02575 YbaB/EbfC DNA-binding family 15 103 2.6E-32 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_27425 676a258ade35339cc14cc12faa0de50d 121 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 9 95 6.3E-24 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_27425 676a258ade35339cc14cc12faa0de50d 121 PIRSF PIRSF004555 6 119 1.4E-33 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 Gene3D G3DSA:2.60.40.10 183 274 2.5E-25 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 SUPERFAMILY SSF49785 32 174 4.25E-31 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 Pfam PF00553 Cellulose binding domain 761 860 1.4E-25 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 Gene3D G3DSA:2.60.120.260 30 175 3.2E-32 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 Gene3D G3DSA:1.50.10.10 276 752 3.2E-188 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 SMART SM00637 761 860 1.7E-38 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 Pfam PF02927 Cellulase N-terminal ig-like domain 185 266 1.7E-22 T 14-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 Pfam PF00759 Glycosyl hydrolase family 9 280 744 1.5E-98 T 14-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 825 838 - T 14-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 SUPERFAMILY SSF81296 182 273 5.67E-23 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 Gene3D G3DSA:2.60.40.290 755 861 1.4E-31 T 14-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 SUPERFAMILY SSF48208 277 748 7.29E-129 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 SUPERFAMILY SSF49384 757 860 1.53E-27 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 Pfam PF02018 Carbohydrate binding domain 36 156 3.1E-10 T 14-10-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 A4R43_06440 422f488b847ad2aaabe902f76dc43730 861 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 721 739 - T 14-10-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4R43_29565 862d2854b51b37f1cdf34ed04e3d968a 194 Gene3D G3DSA:3.40.50.10320 1 187 1.1E-29 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_29565 862d2854b51b37f1cdf34ed04e3d968a 194 SUPERFAMILY SSF102588 2 183 1.96E-31 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_35830 7b55fa1f569e15ea1dae272b2e52f518 218 SUPERFAMILY SSF47240 12 133 4.06E-8 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_35830 7b55fa1f569e15ea1dae272b2e52f518 218 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 7 189 9.2E-84 T 14-10-2018 A4R43_35830 7b55fa1f569e15ea1dae272b2e52f518 218 Gene3D G3DSA:1.20.1260.10 2 218 5.5E-78 T 14-10-2018 IPR012347 Ferritin-like A4R43_11555 a7942fc215a42787333daacf852b322d 476 SUPERFAMILY SSF51206 92 228 2.49E-22 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like A4R43_11555 a7942fc215a42787333daacf852b322d 476 Pfam PF00027 Cyclic nucleotide-binding domain 121 204 8.0E-12 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_11555 a7942fc215a42787333daacf852b322d 476 Gene3D G3DSA:2.60.120.10 93 233 4.1E-20 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_11555 a7942fc215a42787333daacf852b322d 476 SMART SM00100 101 224 1.5E-6 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_30350 5bd3668e2b00b13583d3f6aaa34b5168 86 Pfam PF00239 Resolvase, N terminal domain 1 64 6.7E-10 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4R43_30350 5bd3668e2b00b13583d3f6aaa34b5168 86 Gene3D G3DSA:3.40.50.1390 1 69 6.0E-9 T 14-10-2018 A4R43_30350 5bd3668e2b00b13583d3f6aaa34b5168 86 SUPERFAMILY SSF53041 1 61 1.57E-8 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4R43_23595 b122c094587d59e5e1032d357cefd6ff 405 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 9 339 3.7E-47 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4R43_23595 b122c094587d59e5e1032d357cefd6ff 405 Gene3D G3DSA:3.20.20.70 5 351 2.3E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_23595 b122c094587d59e5e1032d357cefd6ff 405 SUPERFAMILY SSF51395 5 353 9.53E-93 T 14-10-2018 A4R43_08580 6ec1a26bec11171eacee144d54c2e398 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08580 6ec1a26bec11171eacee144d54c2e398 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08580 6ec1a26bec11171eacee144d54c2e398 200 Gene3D G3DSA:1.10.357.10 2 196 8.8E-39 T 14-10-2018 A4R43_08580 6ec1a26bec11171eacee144d54c2e398 200 SUPERFAMILY SSF46689 4 78 1.9E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08580 6ec1a26bec11171eacee144d54c2e398 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 6.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08580 6ec1a26bec11171eacee144d54c2e398 200 Pfam PF13305 WHG domain 91 170 4.7E-6 T 14-10-2018 IPR025996 WHG domain A4R43_08580 6ec1a26bec11171eacee144d54c2e398 200 SUPERFAMILY SSF48498 84 182 3.11E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_26375 6b63236037273d16517109f099fddc4f 163 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 11 163 5.5E-58 T 14-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit A4R43_26375 6b63236037273d16517109f099fddc4f 163 SUPERFAMILY SSF117916 5 93 3.6E-23 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4R43_26375 6b63236037273d16517109f099fddc4f 163 Pfam PF01883 Iron-sulfur cluster assembly protein 9 71 5.5E-16 T 14-10-2018 IPR002744 MIP18 family-like A4R43_26375 6b63236037273d16517109f099fddc4f 163 Gene3D G3DSA:3.30.300.130 3 94 1.4E-23 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 167 178 4.0E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 178 197 4.0E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 151 167 4.0E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 Pfam PF13404 AsnC-type helix-turn-helix domain 152 191 4.9E-9 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 Pfam PF13404 AsnC-type helix-turn-helix domain 2 41 3.8E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 Gene3D G3DSA:3.30.70.920 52 138 1.1E-9 T 14-10-2018 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 Gene3D G3DSA:3.30.70.920 210 294 5.6E-6 T 14-10-2018 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 Gene3D G3DSA:1.10.10.10 152 199 2.7E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 Gene3D G3DSA:1.10.10.10 2 51 1.1E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 SUPERFAMILY SSF46785 3 46 2.73E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 SUPERFAMILY SSF46785 151 198 1.56E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 SMART SM00344 1 104 6.6E-8 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 SMART SM00344 151 255 1.8E-8 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 SUPERFAMILY SSF54909 57 136 2.55E-7 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 SUPERFAMILY SSF54909 223 294 9.12E-8 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_00720 caef0c708236dc654a556a8ed3c9f29d 301 Pfam PF01037 Lrp/AsnC ligand binding domain 67 130 5.2E-7 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_14390 d3b2dbce7356f7c9402720214ab51798 128 Pfam PF01042 Endoribonuclease L-PSP 8 125 4.3E-34 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4R43_14390 d3b2dbce7356f7c9402720214ab51798 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 5 125 2.7E-34 T 14-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 A4R43_14390 d3b2dbce7356f7c9402720214ab51798 128 SUPERFAMILY SSF55298 3 127 1.88E-40 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_14390 d3b2dbce7356f7c9402720214ab51798 128 Gene3D G3DSA:3.30.1330.40 1 128 3.5E-42 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_40885 dcbae1708554fe74bf5d07381cda3abb 385 Gene3D G3DSA:3.40.640.10 3 254 1.0E-66 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_40885 dcbae1708554fe74bf5d07381cda3abb 385 Gene3D G3DSA:3.90.1150.10 255 384 3.7E-39 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_40885 dcbae1708554fe74bf5d07381cda3abb 385 SUPERFAMILY SSF53383 22 379 5.21E-83 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_40885 dcbae1708554fe74bf5d07381cda3abb 385 PIRSF PIRSF001434 1 382 5.7E-116 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_40885 dcbae1708554fe74bf5d07381cda3abb 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 379 2.2E-93 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_27410 cd659b2ce8865a0d7c02cd42b67bd3f6 543 SUPERFAMILY SSF53850 26 542 5.07E-112 T 14-10-2018 A4R43_27410 cd659b2ce8865a0d7c02cd42b67bd3f6 543 Gene3D G3DSA:3.40.190.10 222 531 1.1E-124 T 14-10-2018 A4R43_27410 cd659b2ce8865a0d7c02cd42b67bd3f6 543 PIRSF PIRSF002741 1 542 9.4E-90 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_27410 cd659b2ce8865a0d7c02cd42b67bd3f6 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 462 1.5E-80 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_27410 cd659b2ce8865a0d7c02cd42b67bd3f6 543 Gene3D G3DSA:3.90.76.10 55 221 1.1E-124 T 14-10-2018 A4R43_27410 cd659b2ce8865a0d7c02cd42b67bd3f6 543 Gene3D G3DSA:3.10.105.10 302 518 1.1E-124 T 14-10-2018 A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 215 226 - T 14-10-2018 IPR033116 Serine proteases, trypsin family, serine active site A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 SMART SM00020 45 265 1.3E-60 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 SUPERFAMILY SSF50494 28 266 3.03E-58 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 Pfam PF00089 Trypsin 46 265 7.6E-49 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 78 83 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 Gene3D G3DSA:2.40.10.10 58 261 1.7E-72 T 14-10-2018 A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 68 83 8.9E-13 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 124 138 8.9E-13 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 214 226 8.9E-13 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_37445 9d658e5423806e9b507dea535dfdc413 272 Gene3D G3DSA:2.40.10.10 52 259 1.7E-72 T 14-10-2018 A4R43_16465 39fe033a7abdab69fe9e4ecd35a93d7a 492 SUPERFAMILY SSF116726 402 469 6.54E-9 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_16465 39fe033a7abdab69fe9e4ecd35a93d7a 492 Pfam PF02080 TrkA-C domain 408 466 9.8E-8 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4R43_16465 39fe033a7abdab69fe9e4ecd35a93d7a 492 Pfam PF00999 Sodium/hydrogen exchanger family 14 378 5.6E-49 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4R43_16465 39fe033a7abdab69fe9e4ecd35a93d7a 492 Gene3D G3DSA:3.30.70.1450 389 472 3.6E-11 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_16465 39fe033a7abdab69fe9e4ecd35a93d7a 492 Gene3D G3DSA:1.20.1530.20 8 382 1.3E-21 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 322 1.5E-48 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 Gene3D G3DSA:3.30.390.30 346 462 4.4E-35 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 SUPERFAMILY SSF51905 3 318 3.53E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 Gene3D G3DSA:3.50.50.60 156 276 1.6E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PIRSF PIRSF000350 1 445 9.4E-86 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.2E-41 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 4.2E-41 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 4.2E-41 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 4.2E-41 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 4.2E-41 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 4.2E-41 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 4.2E-41 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.3E-23 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 4.3E-23 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 4.3E-23 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 4.3E-23 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 4.3E-23 T 14-10-2018 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 3 460 2.2E-195 T 14-10-2018 IPR017817 Mycothione reductase MetaCyc: PWY-6421 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 Gene3D G3DSA:3.50.50.60 4 332 1.6E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 456 2.6E-28 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4R43_18255 cf910bd1f98c12a3127901bdc97b6968 463 SUPERFAMILY SSF55424 344 458 1.07E-32 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_14285 4f50fa8abe10c9ed77afbd065d5368b7 168 SUPERFAMILY SSF55961 1 148 6.42E-16 T 14-10-2018 A4R43_14285 4f50fa8abe10c9ed77afbd065d5368b7 168 Gene3D G3DSA:3.30.530.20 3 156 2.9E-12 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_38585 4ba88a0bb320cddd5eb2b11582945df4 196 Gene3D G3DSA:3.40.50.1000 30 188 7.2E-18 T 14-10-2018 IPR023214 HAD superfamily A4R43_38585 4ba88a0bb320cddd5eb2b11582945df4 196 Gene3D G3DSA:1.10.150.240 43 109 7.2E-18 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_38585 4ba88a0bb320cddd5eb2b11582945df4 196 SUPERFAMILY SSF56784 29 178 3.3E-8 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 330 7.4E-28 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 Gene3D G3DSA:3.40.50.970 363 544 3.4E-43 T 14-10-2018 A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 SUPERFAMILY SSF52518 10 188 2.16E-43 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 Gene3D G3DSA:3.40.50.970 4 186 1.9E-52 T 14-10-2018 A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 Gene3D G3DSA:3.40.50.1220 196 362 6.6E-38 T 14-10-2018 A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 180 2.0E-48 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 529 5.5E-25 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 SUPERFAMILY SSF52467 166 357 3.82E-37 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_22715 ffadd94f2fc11081b047781c63c47184 550 SUPERFAMILY SSF52518 368 541 3.3E-41 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_06180 bbbedccb62016b0a398130fc7dc9d27a 238 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 95 232 6.9E-15 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_06180 bbbedccb62016b0a398130fc7dc9d27a 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 79 2.4E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06180 bbbedccb62016b0a398130fc7dc9d27a 238 SUPERFAMILY SSF48498 96 235 7.29E-24 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_06180 bbbedccb62016b0a398130fc7dc9d27a 238 Gene3D G3DSA:1.10.357.10 90 238 7.5E-35 T 14-10-2018 A4R43_06180 bbbedccb62016b0a398130fc7dc9d27a 238 SUPERFAMILY SSF46689 24 87 4.1E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_06180 bbbedccb62016b0a398130fc7dc9d27a 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 6.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06180 bbbedccb62016b0a398130fc7dc9d27a 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 6.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06180 bbbedccb62016b0a398130fc7dc9d27a 238 Gene3D G3DSA:1.10.10.60 14 85 9.8E-20 T 14-10-2018 A4R43_29115 d18c49de436c9c7f5f8c9bcf50ad065a 448 Gene3D G3DSA:3.30.200.20 2 95 1.1E-32 T 14-10-2018 A4R43_29115 d18c49de436c9c7f5f8c9bcf50ad065a 448 PIRSF PIRSF000654 21 261 4.7E-21 T 14-10-2018 A4R43_29115 d18c49de436c9c7f5f8c9bcf50ad065a 448 SMART SM00220 12 270 1.1E-55 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_29115 d18c49de436c9c7f5f8c9bcf50ad065a 448 SUPERFAMILY SSF56112 9 290 1.35E-70 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_29115 d18c49de436c9c7f5f8c9bcf50ad065a 448 Pfam PF00069 Protein kinase domain 14 260 4.2E-41 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_29115 d18c49de436c9c7f5f8c9bcf50ad065a 448 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_29115 d18c49de436c9c7f5f8c9bcf50ad065a 448 Gene3D G3DSA:1.10.510.10 97 278 5.2E-50 T 14-10-2018 A4R43_17190 02bf675f7d464ec9961bd7f5104e178d 253 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 2 225 1.2E-28 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase A4R43_17190 02bf675f7d464ec9961bd7f5104e178d 253 SUPERFAMILY SSF51197 3 239 6.68E-45 T 14-10-2018 A4R43_17190 02bf675f7d464ec9961bd7f5104e178d 253 Gene3D G3DSA:2.60.120.620 2 251 2.5E-49 T 14-10-2018 A4R43_20895 1922121e84f1e5ed55bd272fec2c2fc4 216 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 65 210 8.2E-25 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_20895 1922121e84f1e5ed55bd272fec2c2fc4 216 PIRSF PIRSF001467 54 212 6.7E-22 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A4R43_20895 1922121e84f1e5ed55bd272fec2c2fc4 216 SUPERFAMILY SSF50891 63 211 2.19E-34 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_20895 1922121e84f1e5ed55bd272fec2c2fc4 216 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 172 187 2.2E-9 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_20895 1922121e84f1e5ed55bd272fec2c2fc4 216 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 77 92 2.2E-9 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_20895 1922121e84f1e5ed55bd272fec2c2fc4 216 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 145 160 2.2E-9 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4R43_20895 1922121e84f1e5ed55bd272fec2c2fc4 216 Gene3D G3DSA:2.40.100.10 53 215 6.6E-37 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_31240 eb992e307378d71ea07a5a27621678aa 125 Gene3D G3DSA:3.10.180.10 2 125 2.2E-30 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_31240 eb992e307378d71ea07a5a27621678aa 125 SUPERFAMILY SSF54593 5 122 3.38E-12 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_32045 68e08aada8bfeb98765600f769cfcff6 286 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 284 3.1E-78 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A4R43_32045 68e08aada8bfeb98765600f769cfcff6 286 SUPERFAMILY SSF50891 174 283 1.06E-10 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_32045 68e08aada8bfeb98765600f769cfcff6 286 SMART SM00797 25 286 1.8E-88 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A4R43_32045 68e08aada8bfeb98765600f769cfcff6 286 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 283 1.4E-79 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A4R43_32045 68e08aada8bfeb98765600f769cfcff6 286 Gene3D G3DSA:2.40.100.10 171 286 9.0E-40 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_28215 c93ad659952cdaf43b1a7809cfa00585 413 SUPERFAMILY SSF53720 87 148 9.4E-5 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_28215 c93ad659952cdaf43b1a7809cfa00585 413 Pfam PF05893 Acyl-CoA reductase (LuxC) 88 407 7.7E-36 T 14-10-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 PIRSF PIRSF000089 1 319 6.0E-103 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 Gene3D G3DSA:3.40.50.1220 188 319 3.1E-56 T 14-10-2018 A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 SUPERFAMILY SSF52467 192 313 2.64E-47 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 SMART SM00893 4 187 1.5E-30 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 Pfam PF01012 Electron transfer flavoprotein domain 4 174 4.0E-35 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 195 277 4.3E-36 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 258 284 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 SUPERFAMILY SSF52402 4 178 9.07E-43 T 14-10-2018 A4R43_20140 2f4be287bc6bceee68ed51467e0698bb 319 Gene3D G3DSA:3.40.50.620 1 182 2.9E-40 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_15565 cf44a2a3aaebce0bc718ed02e143d944 242 SUPERFAMILY SSF56300 1 223 8.86E-35 T 14-10-2018 A4R43_15565 cf44a2a3aaebce0bc718ed02e143d944 242 Gene3D G3DSA:3.60.21.10 1 231 3.2E-20 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_15565 cf44a2a3aaebce0bc718ed02e143d944 242 Pfam PF00149 Calcineurin-like phosphoesterase 1 203 5.3E-15 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_15565 cf44a2a3aaebce0bc718ed02e143d944 242 PIRSF PIRSF008292 1 234 8.7E-92 T 14-10-2018 IPR016538 Uncharacterised conserved protein UCP008292 A4R43_19955 26484862a034f735449904838b32497d 1111 SUPERFAMILY SSF52743 134 676 4.45E-60 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_19955 26484862a034f735449904838b32497d 1111 Pfam PF00082 Subtilase family 186 649 1.6E-38 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_19955 26484862a034f735449904838b32497d 1111 Gene3D G3DSA:3.40.50.200 165 475 2.6E-38 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_19955 26484862a034f735449904838b32497d 1111 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 266 276 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_19955 26484862a034f735449904838b32497d 1111 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 191 202 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_19955 26484862a034f735449904838b32497d 1111 Pfam PF02225 PA domain 447 515 3.1E-6 T 14-10-2018 IPR003137 PA domain A4R43_19955 26484862a034f735449904838b32497d 1111 Gene3D G3DSA:3.40.50.200 482 679 1.3E-26 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_19955 26484862a034f735449904838b32497d 1111 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 612 622 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_19955 26484862a034f735449904838b32497d 1111 PRINTS PR00723 Subtilisin serine protease family (S8) signature 611 627 1.1E-17 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_19955 26484862a034f735449904838b32497d 1111 PRINTS PR00723 Subtilisin serine protease family (S8) signature 262 275 1.1E-17 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_19955 26484862a034f735449904838b32497d 1111 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 205 1.1E-17 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 PRINTS PR00982 Lysyl-tRNA synthetase signature 821 837 2.1E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 PRINTS PR00982 Lysyl-tRNA synthetase signature 868 885 2.1E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 PRINTS PR00982 Lysyl-tRNA synthetase signature 805 815 2.1E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 PRINTS PR00982 Lysyl-tRNA synthetase signature 850 863 2.1E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 PRINTS PR00982 Lysyl-tRNA synthetase signature 994 1010 2.1E-30 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 Gene3D G3DSA:2.40.50.140 620 762 8.1E-38 T 14-10-2018 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 14 248 1.6E-32 T 14-10-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 Gene3D G3DSA:3.30.930.10 764 1112 1.0E-114 T 14-10-2018 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 SUPERFAMILY SSF50249 625 761 7.93E-33 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 266 565 3.7E-100 T 14-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 Pfam PF00152 tRNA synthetases class II (D, K and N) 769 1107 9.2E-71 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 Pfam PF01336 OB-fold nucleic acid binding domain 677 751 3.8E-10 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 631 1111 35.825 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 627 1109 1.6E-146 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4R43_36235 de808d876b88cae1f8c5475b58d66f96 1112 SUPERFAMILY SSF55681 768 1108 1.63E-100 T 14-10-2018 A4R43_12250 9a68b4ab597b5a63b3f9229bcb1c393a 705 Gene3D G3DSA:3.10.620.30 391 531 1.3E-12 T 14-10-2018 A4R43_12250 9a68b4ab597b5a63b3f9229bcb1c393a 705 Pfam PF01841 Transglutaminase-like superfamily 403 511 3.6E-18 T 14-10-2018 IPR002931 Transglutaminase-like A4R43_12250 9a68b4ab597b5a63b3f9229bcb1c393a 705 SMART SM00460 442 513 2.7E-15 T 14-10-2018 IPR002931 Transglutaminase-like A4R43_12250 9a68b4ab597b5a63b3f9229bcb1c393a 705 SUPERFAMILY SSF54001 388 514 3.11E-19 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 Gene3D G3DSA:3.40.50.300 1 239 1.1E-62 T 14-10-2018 A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 Pfam PF00005 ABC transporter 302 442 1.5E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 SUPERFAMILY SSF52540 2 234 1.44E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 Pfam PF00005 ABC transporter 19 170 1.8E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 SMART SM00382 310 491 2.0E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 SMART SM00382 28 219 1.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 SUPERFAMILY SSF52540 282 502 4.3E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31995 59580d1e11c0d6f3cc9629b757278740 533 Gene3D G3DSA:3.40.50.300 271 512 2.3E-49 T 14-10-2018 A4R43_19365 8b09be8c8a17254f9a470857ad80406b 253 SUPERFAMILY SSF53474 3 248 4.89E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_19365 8b09be8c8a17254f9a470857ad80406b 253 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 5 248 5.3E-87 T 14-10-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 A4R43_19365 8b09be8c8a17254f9a470857ad80406b 253 Gene3D G3DSA:3.40.50.1820 2 251 5.2E-64 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_19365 8b09be8c8a17254f9a470857ad80406b 253 Pfam PF00561 alpha/beta hydrolase fold 19 130 1.1E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_41195 76c1a89ab5563375126875d105e5d553 445 Pfam PF07690 Major Facilitator Superfamily 17 402 1.8E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_41195 76c1a89ab5563375126875d105e5d553 445 SUPERFAMILY SSF103473 5 442 5.89E-61 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_41195 76c1a89ab5563375126875d105e5d553 445 Gene3D G3DSA:1.20.1250.20 247 441 2.7E-18 T 14-10-2018 A4R43_41195 76c1a89ab5563375126875d105e5d553 445 Gene3D G3DSA:1.20.1250.20 6 187 2.9E-35 T 14-10-2018 A4R43_08635 9208a9ff092f533b507ce13b57ed6b77 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 63 97 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_08635 9208a9ff092f533b507ce13b57ed6b77 144 Pfam PF01047 MarR family 31 88 1.4E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_08635 9208a9ff092f533b507ce13b57ed6b77 144 Gene3D G3DSA:1.10.10.10 1 139 1.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08635 9208a9ff092f533b507ce13b57ed6b77 144 SMART SM00347 24 124 1.2E-21 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_08635 9208a9ff092f533b507ce13b57ed6b77 144 SUPERFAMILY SSF46785 7 132 1.05E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 53 65 8.1E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 37 47 8.1E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 341 347 8.1E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 24 36 8.1E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 99 111 8.1E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 370 382 8.1E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 400 504 5.6E-17 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 375 385 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 SUPERFAMILY SSF51905 24 351 3.02E-34 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 Gene3D G3DSA:3.50.50.60 25 389 2.3E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 Gene3D G3DSA:3.30.9.10 103 348 2.3E-101 T 14-10-2018 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 29 46 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 Gene3D G3DSA:1.10.8.870 409 505 8.3E-17 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4R43_25505 cd51e45fc2638a1fb98710fcedfca52d 511 Pfam PF01266 FAD dependent oxidoreductase 25 354 9.9E-48 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_23655 d8e3633273c4d023b442f6bb9ea69546 668 SUPERFAMILY SSF52833 1 126 4.78E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_23655 d8e3633273c4d023b442f6bb9ea69546 668 Pfam PF03190 Protein of unknown function, DUF255 3 163 8.1E-74 T 14-10-2018 IPR004879 Domain of unknown function DUF255 A4R43_23655 d8e3633273c4d023b442f6bb9ea69546 668 Gene3D G3DSA:3.40.30.10 1 168 2.2E-66 T 14-10-2018 A4R43_23655 d8e3633273c4d023b442f6bb9ea69546 668 SUPERFAMILY SSF48208 192 528 4.9E-71 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_23655 d8e3633273c4d023b442f6bb9ea69546 668 PIRSF PIRSF006402 1 668 5.2E-199 T 14-10-2018 IPR024705 Spermatogenesis-associated protein 20 A4R43_23655 d8e3633273c4d023b442f6bb9ea69546 668 Gene3D G3DSA:1.50.10.10 404 570 4.3E-7 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_40275 f194a65988f2b0dae243cec44aaa0ed2 261 Pfam PF00005 ABC transporter 19 167 5.4E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_40275 f194a65988f2b0dae243cec44aaa0ed2 261 SMART SM00382 27 211 6.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_40275 f194a65988f2b0dae243cec44aaa0ed2 261 SUPERFAMILY SSF52540 3 225 5.87E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_40275 f194a65988f2b0dae243cec44aaa0ed2 261 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_40275 f194a65988f2b0dae243cec44aaa0ed2 261 Gene3D G3DSA:3.40.50.300 3 250 1.4E-67 T 14-10-2018 A4R43_35995 62b4a36bc9e672a6e49103f118f8d31d 319 Gene3D G3DSA:1.10.8.300 208 315 8.3E-34 T 14-10-2018 A4R43_35995 62b4a36bc9e672a6e49103f118f8d31d 319 PIRSF PIRSF002849 1 319 1.4E-128 T 14-10-2018 A4R43_35995 62b4a36bc9e672a6e49103f118f8d31d 319 Gene3D G3DSA:3.40.50.300 1 203 3.4E-47 T 14-10-2018 A4R43_35995 62b4a36bc9e672a6e49103f118f8d31d 319 SUPERFAMILY SSF52540 7 295 6.29E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35995 62b4a36bc9e672a6e49103f118f8d31d 319 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 2.8E-63 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 886 900 1.2E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 900 916 1.2E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 916 928 1.2E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 SUPERFAMILY SSF48452 395 775 3.1E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 Pfam PF13191 AAA ATPase domain 14 177 2.6E-22 T 14-10-2018 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 Gene3D G3DSA:1.10.10.10 876 942 4.8E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 SMART SM00421 883 940 6.7E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 ProSitePatterns PS00622 LuxR-type HTH domain signature. 900 927 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 SUPERFAMILY SSF46894 875 938 6.12E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 SUPERFAMILY SSF48452 388 513 1.82E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 Gene3D G3DSA:1.25.40.10 565 875 1.8E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 Pfam PF00196 Bacterial regulatory proteins, luxR family 885 936 9.2E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 SUPERFAMILY SSF52540 14 256 4.09E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05605 3f52e8a0bda74c59c62f6ce3659740a3 956 Gene3D G3DSA:1.25.40.10 316 554 7.7E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_15385 b975a969d8c63f75dbb0439ef631e832 378 SUPERFAMILY SSF55874 227 326 1.56E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_15385 b975a969d8c63f75dbb0439ef631e832 378 Pfam PF07730 Histidine kinase 149 210 4.0E-12 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_15385 b975a969d8c63f75dbb0439ef631e832 378 Gene3D G3DSA:3.30.565.10 219 338 6.1E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_17490 004ba1df8dfe011e3dd2c54acdb0f0a9 108 SUPERFAMILY SSF82607 10 98 1.96E-12 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_17490 004ba1df8dfe011e3dd2c54acdb0f0a9 108 Pfam PF02575 YbaB/EbfC DNA-binding family 17 100 2.7E-15 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_17490 004ba1df8dfe011e3dd2c54acdb0f0a9 108 Gene3D G3DSA:3.30.1310.10 5 107 3.2E-14 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_19970 2fe3807c36669bd972b48130770a4abf 297 SUPERFAMILY SSF51679 16 292 8.1E-34 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_19970 2fe3807c36669bd972b48130770a4abf 297 Gene3D G3DSA:3.20.20.30 15 291 3.5E-29 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_19970 2fe3807c36669bd972b48130770a4abf 297 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 11 291 1.3E-77 T 14-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted A4R43_19970 2fe3807c36669bd972b48130770a4abf 297 Pfam PF00296 Luciferase-like monooxygenase 26 268 2.4E-15 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_31490 8b66de6c2e9f1f9a6c5015c9de332f6d 324 Gene3D G3DSA:3.40.50.2300 131 266 1.7E-65 T 14-10-2018 A4R43_31490 8b66de6c2e9f1f9a6c5015c9de332f6d 324 SUPERFAMILY SSF53822 25 295 1.11E-58 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_31490 8b66de6c2e9f1f9a6c5015c9de332f6d 324 Pfam PF13407 Periplasmic binding protein domain 28 287 1.1E-48 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_31490 8b66de6c2e9f1f9a6c5015c9de332f6d 324 Gene3D G3DSA:3.40.50.2300 29 285 1.7E-65 T 14-10-2018 A4R43_16765 463087fd1b15835a19fb9a7ce7d8a44a 199 Gene3D G3DSA:1.10.357.10 6 158 8.8E-30 T 14-10-2018 A4R43_16765 463087fd1b15835a19fb9a7ce7d8a44a 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16765 463087fd1b15835a19fb9a7ce7d8a44a 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16765 463087fd1b15835a19fb9a7ce7d8a44a 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 6.4E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16765 463087fd1b15835a19fb9a7ce7d8a44a 199 SUPERFAMILY SSF46689 12 81 3.85E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17140 64813704cc0b8e24c2db1b5d75b61f37 350 SUPERFAMILY SSF51735 1 346 3.95E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_17140 64813704cc0b8e24c2db1b5d75b61f37 350 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 124 1.2E-8 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_17140 64813704cc0b8e24c2db1b5d75b61f37 350 Gene3D G3DSA:3.40.50.720 1 350 1.3E-114 T 14-10-2018 A4R43_10320 96d851581c95f414f7b448e0deb1e091 332 SUPERFAMILY SSF89733 1 330 1.31E-102 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 A4R43_10320 96d851581c95f414f7b448e0deb1e091 332 Pfam PF02615 Malate/L-lactate dehydrogenase 4 326 5.3E-113 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 A4R43_10320 96d851581c95f414f7b448e0deb1e091 332 Gene3D G3DSA:1.10.1530.10 13 329 1.7E-110 T 14-10-2018 A4R43_10320 96d851581c95f414f7b448e0deb1e091 332 Gene3D G3DSA:3.30.1370.60 67 300 1.7E-110 T 14-10-2018 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Pfam PF00975 Thioesterase domain 1032 1251 7.0E-19 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 SUPERFAMILY SSF56801 453 954 2.62E-89 T 14-10-2018 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 SUPERFAMILY SSF52777 219 456 1.33E-49 T 14-10-2018 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Gene3D G3DSA:3.30.559.30 215 457 1.2E-106 T 14-10-2018 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Gene3D G3DSA:1.10.1200.10 935 1012 1.2E-19 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Gene3D G3DSA:3.40.50.1820 1020 1257 5.2E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 SUPERFAMILY SSF47336 937 1008 1.58E-14 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Gene3D G3DSA:3.30.300.30 831 934 6.6E-20 T 14-10-2018 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 SUPERFAMILY SSF52777 39 211 2.0E-33 T 14-10-2018 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Pfam PF00668 Condensation domain 36 471 1.4E-74 T 14-10-2018 IPR001242 Condensation domain A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Pfam PF00550 Phosphopantetheine attachment site 945 1007 2.7E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Gene3D G3DSA:3.30.559.10 38 402 1.2E-106 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 SMART SM00823 Phosphopantetheine attachment site 943 1012 4.7E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Pfam PF13193 AMP-binding enzyme C-terminal domain 845 915 7.5E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 SUPERFAMILY SSF53474 1017 1252 2.36E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Pfam PF00501 AMP-binding enzyme 732 836 2.9E-14 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Pfam PF00501 AMP-binding enzyme 493 723 3.2E-26 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Gene3D G3DSA:3.40.50.12780 484 726 4.9E-43 T 14-10-2018 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 Gene3D G3DSA:3.40.50.12780 727 828 1.2E-27 T 14-10-2018 A4R43_02210 f1e4bc8b52e424099e3075d017c89761 1262 SMART SM00824 Thioesterase 1033 1253 1.1E-4 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4R43_03150 74f81202cf5c1f9c9c59443cb74106f5 462 Gene3D G3DSA:1.20.1250.20 257 442 4.5E-12 T 14-10-2018 A4R43_03150 74f81202cf5c1f9c9c59443cb74106f5 462 Pfam PF07690 Major Facilitator Superfamily 17 399 4.0E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_03150 74f81202cf5c1f9c9c59443cb74106f5 462 SUPERFAMILY SSF103473 5 439 6.02E-53 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_03150 74f81202cf5c1f9c9c59443cb74106f5 462 Gene3D G3DSA:1.20.1720.10 12 246 9.6E-43 T 14-10-2018 A4R43_00030 a6aca3832e59567b3635a3dce3b7647e 872 SMART SM00028 158 191 0.42 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_00030 a6aca3832e59567b3635a3dce3b7647e 872 SMART SM00028 108 141 28.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_00030 a6aca3832e59567b3635a3dce3b7647e 872 SMART SM00028 198 231 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_00030 a6aca3832e59567b3635a3dce3b7647e 872 Gene3D G3DSA:1.25.40.10 111 342 1.3E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_00030 a6aca3832e59567b3635a3dce3b7647e 872 SUPERFAMILY SSF48452 108 226 6.94E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_00030 a6aca3832e59567b3635a3dce3b7647e 872 Pfam PF12770 CHAT domain 630 856 1.7E-30 T 14-10-2018 IPR024983 CHAT domain A4R43_12070 92e0d3e8160fbf5ef81d7f92a97505d0 441 Gene3D G3DSA:3.40.190.10 137 404 2.9E-40 T 14-10-2018 A4R43_12070 92e0d3e8160fbf5ef81d7f92a97505d0 441 Pfam PF01547 Bacterial extracellular solute-binding protein 40 340 1.1E-15 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_12070 92e0d3e8160fbf5ef81d7f92a97505d0 441 Gene3D G3DSA:3.40.190.10 42 371 2.9E-40 T 14-10-2018 A4R43_12070 92e0d3e8160fbf5ef81d7f92a97505d0 441 SUPERFAMILY SSF53850 27 417 6.73E-36 T 14-10-2018 A4R43_27770 d3a4c13ed8514cb92643a9a9c34e3b6f 330 Pfam PF00248 Aldo/keto reductase family 16 307 4.0E-65 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_27770 d3a4c13ed8514cb92643a9a9c34e3b6f 330 SUPERFAMILY SSF51430 1 308 1.83E-92 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_27770 d3a4c13ed8514cb92643a9a9c34e3b6f 330 Gene3D G3DSA:3.20.20.100 1 328 5.5E-108 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_05545 55fc3c7e9c768f376dd6f5dc2f30c8db 168 Gene3D G3DSA:3.60.21.10 1 162 2.3E-38 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_05545 55fc3c7e9c768f376dd6f5dc2f30c8db 168 SUPERFAMILY SSF56300 1 164 4.85E-34 T 14-10-2018 A4R43_05545 55fc3c7e9c768f376dd6f5dc2f30c8db 168 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 148 1.4E-28 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A4R43_05545 55fc3c7e9c768f376dd6f5dc2f30c8db 168 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 149 3.1E-28 T 14-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A4R43_39140 3473bb18245e7e8a42629197c2262854 493 SUPERFAMILY SSF52540 5 231 1.3E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39140 3473bb18245e7e8a42629197c2262854 493 SUPERFAMILY SSF52540 260 470 5.59E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39140 3473bb18245e7e8a42629197c2262854 493 SMART SM00382 28 247 6.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_39140 3473bb18245e7e8a42629197c2262854 493 SMART SM00382 278 466 3.7E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_39140 3473bb18245e7e8a42629197c2262854 493 Pfam PF00005 ABC transporter 269 417 3.6E-19 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_39140 3473bb18245e7e8a42629197c2262854 493 Gene3D G3DSA:3.40.50.300 2 238 8.3E-51 T 14-10-2018 A4R43_39140 3473bb18245e7e8a42629197c2262854 493 Gene3D G3DSA:3.40.50.300 248 484 7.5E-42 T 14-10-2018 A4R43_39140 3473bb18245e7e8a42629197c2262854 493 Pfam PF00005 ABC transporter 19 169 1.2E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_39140 3473bb18245e7e8a42629197c2262854 493 ProSitePatterns PS00211 ABC transporters family signature. 390 404 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 Gene3D G3DSA:3.40.50.720 4 270 1.1E-73 T 14-10-2018 A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 Pfam PF00106 short chain dehydrogenase 9 190 8.0E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 SUPERFAMILY SSF51735 7 250 2.08E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 5.9E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 5.9E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 5.9E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20535 5063d1454631e4a412352a1deb2a34d0 270 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 SUPERFAMILY SSF51735 10 256 2.76E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 Gene3D G3DSA:3.40.50.720 2 256 1.6E-81 T 14-10-2018 A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 2.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 193 8.8E-4 T 14-10-2018 A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 255 1.9E-63 T 14-10-2018 A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40300 b2cb37ebadc180e958013c3d28686544 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06800 ea5f2b77f83d3e836fd6c095f4285e58 455 Pfam PF03929 PepSY-associated TM region 27 391 3.6E-73 T 14-10-2018 IPR005625 PepSY-associated TM protein A4R43_22270 66057946efdf9c9666efea2736f1bf6e 560 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 45 460 3.1E-73 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_22270 66057946efdf9c9666efea2736f1bf6e 560 Gene3D G3DSA:1.20.1730.10 34 526 8.4E-108 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_22270 66057946efdf9c9666efea2736f1bf6e 560 Pfam PF00474 Sodium:solute symporter family 45 459 4.2E-49 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_22270 66057946efdf9c9666efea2736f1bf6e 560 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 160 185 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 322 3.7E-135 T 14-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 SUPERFAMILY SSF50129 1 138 2.13E-38 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 Gene3D G3DSA:3.40.50.720 120 260 2.5E-100 T 14-10-2018 A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 Pfam PF00107 Zinc-binding dehydrogenase 151 264 1.1E-26 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 SUPERFAMILY SSF51735 114 285 1.49E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 Gene3D G3DSA:3.90.180.10 13 321 2.5E-100 T 14-10-2018 A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 8.4E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_28045 8fa7c799edb9e8f68b614c0e8f578fb4 325 SMART SM00829 10 321 1.4E-35 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_09455 5a771f1740d9188bf24899911580b612 531 SUPERFAMILY SSF51905 5 359 3.98E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09455 5a771f1740d9188bf24899911580b612 531 Gene3D G3DSA:3.40.30.120 405 530 7.6E-29 T 14-10-2018 A4R43_09455 5a771f1740d9188bf24899911580b612 531 Pfam PF01494 FAD binding domain 5 354 1.5E-71 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_09455 5a771f1740d9188bf24899911580b612 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.8E-41 T 14-10-2018 A4R43_09455 5a771f1740d9188bf24899911580b612 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 341 3.8E-41 T 14-10-2018 A4R43_09455 5a771f1740d9188bf24899911580b612 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 3.8E-41 T 14-10-2018 A4R43_09455 5a771f1740d9188bf24899911580b612 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 3.8E-41 T 14-10-2018 A4R43_09455 5a771f1740d9188bf24899911580b612 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 3.8E-41 T 14-10-2018 A4R43_09455 5a771f1740d9188bf24899911580b612 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 3.8E-41 T 14-10-2018 A4R43_09455 5a771f1740d9188bf24899911580b612 531 Gene3D G3DSA:3.30.9.50 73 287 3.9E-104 T 14-10-2018 A4R43_09455 5a771f1740d9188bf24899911580b612 531 Gene3D G3DSA:3.50.50.60 6 350 3.9E-104 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_31300 9cc565d9ca1480e8a860e7384ae241ac 228 Pfam PF00188 Cysteine-rich secretory protein family 115 226 1.3E-22 T 14-10-2018 IPR014044 CAP domain A4R43_31300 9cc565d9ca1480e8a860e7384ae241ac 228 Gene3D G3DSA:3.40.33.10 26 227 1.9E-53 T 14-10-2018 IPR035940 CAP superfamily A4R43_31300 9cc565d9ca1480e8a860e7384ae241ac 228 SUPERFAMILY SSF55797 111 227 2.04E-22 T 14-10-2018 IPR035940 CAP superfamily A4R43_37160 2dcfe13131786b957ebcc7ba559eda6d 414 Pfam PF13535 ATP-grasp domain 143 295 3.9E-20 T 14-10-2018 A4R43_37160 2dcfe13131786b957ebcc7ba559eda6d 414 Gene3D G3DSA:3.30.470.20 100 413 3.1E-71 T 14-10-2018 A4R43_37160 2dcfe13131786b957ebcc7ba559eda6d 414 SUPERFAMILY SSF56059 91 317 1.38E-31 T 14-10-2018 A4R43_41670 3f14b2c027df5928c3cdea2a7ce6797d 363 Pfam PF01032 FecCD transport family 35 355 3.3E-88 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_41670 3f14b2c027df5928c3cdea2a7ce6797d 363 SUPERFAMILY SSF81345 28 356 4.97E-74 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_41670 3f14b2c027df5928c3cdea2a7ce6797d 363 Gene3D G3DSA:1.10.3470.10 25 359 1.5E-94 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_40090 b5bff504d6789e56876d405b9e17df31 216 SMART SM01110 28 201 0.0026 T 14-10-2018 IPR000675 Cutinase/acetylxylan esterase GO:0016787 A4R43_40090 b5bff504d6789e56876d405b9e17df31 216 SUPERFAMILY SSF53474 21 180 2.54E-14 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40090 b5bff504d6789e56876d405b9e17df31 216 Pfam PF01083 Cutinase 57 177 2.0E-8 T 14-10-2018 IPR000675 Cutinase/acetylxylan esterase GO:0016787 A4R43_40090 b5bff504d6789e56876d405b9e17df31 216 Gene3D G3DSA:3.40.50.1820 5 208 4.8E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27080 310ba89e919747e6ebf30034d4bd4fa2 193 Pfam PF13302 Acetyltransferase (GNAT) domain 15 152 3.2E-19 T 14-10-2018 IPR000182 GNAT domain A4R43_27080 310ba89e919747e6ebf30034d4bd4fa2 193 Gene3D G3DSA:3.40.630.30 2 193 3.3E-52 T 14-10-2018 A4R43_27080 310ba89e919747e6ebf30034d4bd4fa2 193 SUPERFAMILY SSF55729 6 177 4.21E-41 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_13665 9d975f6bc2d052aefcfaae5386520e44 212 Gene3D G3DSA:1.20.144.10 99 196 6.1E-11 T 14-10-2018 A4R43_13665 9d975f6bc2d052aefcfaae5386520e44 212 Pfam PF01569 PAP2 superfamily 100 177 2.0E-7 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_13665 9d975f6bc2d052aefcfaae5386520e44 212 SUPERFAMILY SSF48317 6 185 3.27E-16 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4R43_14770 236fac99b4015a4eab8c7ecf7624a50f 260 Pfam PF00561 alpha/beta hydrolase fold 22 142 2.5E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_14770 236fac99b4015a4eab8c7ecf7624a50f 260 Gene3D G3DSA:3.40.50.1820 2 256 5.6E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14770 236fac99b4015a4eab8c7ecf7624a50f 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 6.8E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_14770 236fac99b4015a4eab8c7ecf7624a50f 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 6.8E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_14770 236fac99b4015a4eab8c7ecf7624a50f 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 6.8E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_14770 236fac99b4015a4eab8c7ecf7624a50f 260 SUPERFAMILY SSF53474 3 254 5.99E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22645 a68ad00aa3c2b29cda5052ff0bfee0bb 265 SUPERFAMILY SSF53474 3 261 1.43E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22645 a68ad00aa3c2b29cda5052ff0bfee0bb 265 Pfam PF12697 Alpha/beta hydrolase family 7 253 2.2E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22645 a68ad00aa3c2b29cda5052ff0bfee0bb 265 Gene3D G3DSA:3.40.50.1820 1 263 1.8E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 ProSitePatterns PS00211 ABC transporters family signature. 990 1004 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 Gene3D G3DSA:3.40.50.300 855 1073 9.9E-57 T 14-10-2018 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 Gene3D G3DSA:1.20.1560.10 549 854 6.3E-13 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 Gene3D G3DSA:1.20.1560.10 13 325 4.6E-42 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 SUPERFAMILY SSF90123 21 324 5.49E-47 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 SUPERFAMILY SSF52540 866 1068 1.33E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 Pfam PF00005 ABC transporter 355 496 2.9E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 Pfam PF00664 ABC transporter transmembrane region 26 278 1.2E-23 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 SMART SM00382 360 560 3.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 SMART SM00382 897 1066 3.4E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 562 1050 3.8E-130 T 14-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 21 534 2.1E-151 T 14-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 Gene3D G3DSA:3.40.50.300 330 538 4.6E-52 T 14-10-2018 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 Pfam PF00005 ABC transporter 888 1020 8.4E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 SUPERFAMILY SSF52540 330 527 9.57E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28510 0fb81b5aed69bd1c138820b7a11bf88f 1075 SUPERFAMILY SSF90123 563 846 4.84E-25 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_33070 58977e1a666f72ec60d4ce8cee28051a 234 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 227 4.9E-51 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4R43_33070 58977e1a666f72ec60d4ce8cee28051a 234 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4R43_33070 58977e1a666f72ec60d4ce8cee28051a 234 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 227 3.6E-62 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4R43_33070 58977e1a666f72ec60d4ce8cee28051a 234 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 227 30.927 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4R43_33070 58977e1a666f72ec60d4ce8cee28051a 234 SUPERFAMILY SSF53335 3 225 2.46E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_33070 58977e1a666f72ec60d4ce8cee28051a 234 Gene3D G3DSA:3.40.50.150 19 228 8.8E-52 T 14-10-2018 A4R43_19885 bc53f045eb1eb5631c63ee1394324ebb 201 SUPERFAMILY SSF48498 86 187 1.19E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_19885 bc53f045eb1eb5631c63ee1394324ebb 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19885 bc53f045eb1eb5631c63ee1394324ebb 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19885 bc53f045eb1eb5631c63ee1394324ebb 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.9E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19885 bc53f045eb1eb5631c63ee1394324ebb 201 SUPERFAMILY SSF46689 12 92 1.23E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19885 bc53f045eb1eb5631c63ee1394324ebb 201 Gene3D G3DSA:1.10.357.10 1 201 9.0E-62 T 14-10-2018 A4R43_12330 80c206b2b4440cd7ad4bdca7a17d6fc2 194 Pfam PF15567 Immunity protein 35 86 148 7.2E-10 T 14-10-2018 IPR029082 Immunity protein 35 A4R43_20260 611732ce70f98231e0455c6f9e88573e 269 Gene3D G3DSA:1.10.260.40 7 93 8.0E-13 T 14-10-2018 A4R43_20260 611732ce70f98231e0455c6f9e88573e 269 Pfam PF13560 Helix-turn-helix domain 9 70 6.3E-12 T 14-10-2018 A4R43_20260 611732ce70f98231e0455c6f9e88573e 269 SUPERFAMILY SSF47413 4 66 4.29E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_20260 611732ce70f98231e0455c6f9e88573e 269 SMART SM00530 12 67 2.8E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_05235 669b667646eb8fa3b08bfe0891fdc05d 277 SUPERFAMILY SSF51735 2 245 1.14E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_05235 669b667646eb8fa3b08bfe0891fdc05d 277 Gene3D G3DSA:3.40.50.720 1 275 2.7E-69 T 14-10-2018 A4R43_05235 669b667646eb8fa3b08bfe0891fdc05d 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_05235 669b667646eb8fa3b08bfe0891fdc05d 277 Pfam PF00106 short chain dehydrogenase 7 202 3.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05235 669b667646eb8fa3b08bfe0891fdc05d 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05235 669b667646eb8fa3b08bfe0891fdc05d 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 8.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05235 669b667646eb8fa3b08bfe0891fdc05d 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 8.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19200 3c555bdf6c2fed21614da1286ccb9beb 163 Pfam PF07681 DoxX 26 110 5.5E-5 T 14-10-2018 IPR032808 DoxX family A4R43_08360 008548f31d6f7a99891455a5e650dc6c 534 SUPERFAMILY SSF51556 60 459 7.15E-34 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_08360 008548f31d6f7a99891455a5e650dc6c 534 Gene3D G3DSA:2.30.40.10 12 476 3.8E-89 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_08360 008548f31d6f7a99891455a5e650dc6c 534 Pfam PF07969 Amidohydrolase family 49 527 2.5E-85 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_08360 008548f31d6f7a99891455a5e650dc6c 534 Gene3D G3DSA:3.20.20.140 61 463 3.8E-89 T 14-10-2018 A4R43_08360 008548f31d6f7a99891455a5e650dc6c 534 SUPERFAMILY SSF51338 6 75 2.39E-13 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_08360 008548f31d6f7a99891455a5e650dc6c 534 Gene3D G3DSA:3.10.310.70 79 185 3.8E-89 T 14-10-2018 A4R43_39455 b062466411a0445aeca45161526fadbd 480 Pfam PF13520 Amino acid permease 34 444 3.4E-59 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_39455 b062466411a0445aeca45161526fadbd 480 Gene3D G3DSA:1.20.1740.10 29 477 3.2E-117 T 14-10-2018 A4R43_39455 b062466411a0445aeca45161526fadbd 480 PIRSF PIRSF006060 19 479 1.4E-85 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_34100 134805516397c9a5885b47d7f52a336b 160 Pfam PF00380 Ribosomal protein S9/S16 40 160 5.9E-43 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A4R43_34100 134805516397c9a5885b47d7f52a336b 160 Gene3D G3DSA:3.30.230.10 32 160 2.5E-48 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_34100 134805516397c9a5885b47d7f52a336b 160 SUPERFAMILY SSF54211 36 160 2.05E-44 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_34100 134805516397c9a5885b47d7f52a336b 160 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 31 160 32.664 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid A4R43_34100 134805516397c9a5885b47d7f52a336b 160 ProSitePatterns PS00360 Ribosomal protein S9 signature. 99 117 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A4R43_06255 26234a275a854a599bb5d8c256232d17 141 Pfam PF13581 Histidine kinase-like ATPase domain 22 130 1.1E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_06255 26234a275a854a599bb5d8c256232d17 141 Gene3D G3DSA:3.30.565.10 15 138 5.3E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27695 16502f795a8899445b3503272611f3aa 404 SUPERFAMILY SSF103473 9 403 4.71E-38 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_27695 16502f795a8899445b3503272611f3aa 404 Pfam PF05977 Transmembrane secretion effector 3 402 4.8E-24 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_27695 16502f795a8899445b3503272611f3aa 404 Gene3D G3DSA:1.20.1250.20 8 396 2.6E-31 T 14-10-2018 A4R43_12780 4c90874ff9e6ed837501bf8054808d94 122 Pfam PF00011 Hsp20/alpha crystallin family 22 117 8.7E-19 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4R43_12780 4c90874ff9e6ed837501bf8054808d94 122 Gene3D G3DSA:2.60.40.790 2 119 5.6E-24 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_12780 4c90874ff9e6ed837501bf8054808d94 122 SUPERFAMILY SSF49764 4 117 2.07E-28 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_06050 6973842e293e8c74579c6142e0bc32a2 184 Pfam PF00583 Acetyltransferase (GNAT) family 57 160 1.0E-7 T 14-10-2018 IPR000182 GNAT domain A4R43_06050 6973842e293e8c74579c6142e0bc32a2 184 SUPERFAMILY SSF55729 1 181 2.96E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_06050 6973842e293e8c74579c6142e0bc32a2 184 Gene3D G3DSA:3.40.630.30 2 184 1.2E-39 T 14-10-2018 A4R43_04050 81d0e161db1fd7110a1ae14c5f62b8fe 267 Pfam PF00005 ABC transporter 25 182 2.3E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_04050 81d0e161db1fd7110a1ae14c5f62b8fe 267 SUPERFAMILY SSF52540 5 252 5.66E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04050 81d0e161db1fd7110a1ae14c5f62b8fe 267 Gene3D G3DSA:3.40.50.300 1 267 2.0E-76 T 14-10-2018 A4R43_04050 81d0e161db1fd7110a1ae14c5f62b8fe 267 SMART SM00382 33 231 5.7E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_27640 ca3f9e39a03325da860bb14087715454 66 SUPERFAMILY SSF69047 5 63 3.01E-10 T 14-10-2018 IPR036629 YjbJ superfamily A4R43_27640 ca3f9e39a03325da860bb14087715454 66 Pfam PF05532 CsbD-like 5 56 2.1E-14 T 14-10-2018 IPR008462 CsbD-like domain A4R43_27640 ca3f9e39a03325da860bb14087715454 66 Gene3D G3DSA:1.10.1470.10 4 64 1.9E-6 T 14-10-2018 IPR036629 YjbJ superfamily A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 SUPERFAMILY SSF55073 436 582 8.63E-21 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 SUPERFAMILY SSF141868 607 853 1.11E-81 T 14-10-2018 IPR035919 EAL domain superfamily A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 SMART SM00052 600 845 1.3E-100 T 14-10-2018 IPR001633 EAL domain A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 SMART SM00065 288 428 2.4E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 Pfam PF00990 Diguanylate cyclase, GGDEF domain 431 580 1.3E-16 T 14-10-2018 IPR000160 GGDEF domain A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 SUPERFAMILY SSF55781 310 423 1.18E-12 T 14-10-2018 A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 Gene3D G3DSA:3.20.20.450 601 853 1.4E-89 T 14-10-2018 IPR035919 EAL domain superfamily A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 Pfam PF00563 EAL domain 607 840 7.0E-69 T 14-10-2018 IPR001633 EAL domain A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 Pfam PF01590 GAF domain 321 418 2.2E-5 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 Gene3D G3DSA:3.30.450.40 247 427 3.2E-13 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 428 580 3.3E-12 T 14-10-2018 IPR000160 GGDEF domain A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 SMART SM00267 420 590 3.6E-18 T 14-10-2018 IPR000160 GGDEF domain A4R43_33485 d4b1c2bb36a4e686b0392e6bee454d7f 870 Gene3D G3DSA:3.30.70.270 428 589 2.6E-27 T 14-10-2018 A4R43_03335 608501b750b2e1490cbd02031ffd6ad8 255 SUPERFAMILY SSF51182 19 179 8.43E-16 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_03335 608501b750b2e1490cbd02031ffd6ad8 255 Gene3D G3DSA:1.10.10.60 156 253 2.4E-18 T 14-10-2018 A4R43_03335 608501b750b2e1490cbd02031ffd6ad8 255 Pfam PF12833 Helix-turn-helix domain 176 251 2.0E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03335 608501b750b2e1490cbd02031ffd6ad8 255 SMART SM00342 170 251 1.7E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03335 608501b750b2e1490cbd02031ffd6ad8 255 SUPERFAMILY SSF46689 212 251 1.66E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03335 608501b750b2e1490cbd02031ffd6ad8 255 Gene3D G3DSA:2.60.120.10 5 92 8.8E-7 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 123 194 7.6E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 71 202 2.6E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 105 206 5.7E-13 T 14-10-2018 A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 120 133 1.6E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 188 1.6E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 1.6E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.6E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 195 208 1.6E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 Gene3D G3DSA:3.40.50.1000 1 223 6.7E-32 T 14-10-2018 IPR023214 HAD superfamily A4R43_26590 45391616026f88bb4aaf4dc3550eb39f 228 SUPERFAMILY SSF56784 6 212 8.87E-32 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_19515 2e90b8906234236c1b266158a6753553 324 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 15 320 5.3E-83 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4R43_19515 2e90b8906234236c1b266158a6753553 324 SUPERFAMILY SSF55326 14 148 1.44E-33 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4R43_19515 2e90b8906234236c1b266158a6753553 324 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 14 321 26.838 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4R43_19515 2e90b8906234236c1b266158a6753553 324 Gene3D G3DSA:3.30.1330.10 10 150 1.1E-43 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4R43_19515 2e90b8906234236c1b266158a6753553 324 Pfam PF00586 AIR synthase related protein, N-terminal domain 39 148 1.2E-20 T 14-10-2018 IPR016188 PurM-like, N-terminal domain A4R43_19515 2e90b8906234236c1b266158a6753553 324 SUPERFAMILY SSF56042 155 306 1.66E-30 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4R43_19515 2e90b8906234236c1b266158a6753553 324 PIRSF PIRSF005303 10 321 7.1E-88 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4R43_19515 2e90b8906234236c1b266158a6753553 324 Gene3D G3DSA:3.90.650.10 157 321 7.8E-49 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4R43_08045 a87f124533abaacd528966b18c012fe8 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 46 9.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08045 a87f124533abaacd528966b18c012fe8 189 Gene3D G3DSA:1.10.357.10 50 184 1.1E-28 T 14-10-2018 A4R43_08045 a87f124533abaacd528966b18c012fe8 189 SUPERFAMILY SSF48498 77 183 1.19E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_08045 a87f124533abaacd528966b18c012fe8 189 Gene3D G3DSA:1.10.10.60 1 49 1.6E-17 T 14-10-2018 A4R43_08045 a87f124533abaacd528966b18c012fe8 189 SUPERFAMILY SSF46689 6 72 7.7E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08045 a87f124533abaacd528966b18c012fe8 189 Pfam PF13305 WHG domain 84 160 1.4E-5 T 14-10-2018 IPR025996 WHG domain A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 Pfam PF11799 impB/mucB/samB family C-terminal domain 242 337 4.4E-13 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 Pfam PF14520 Helix-hairpin-helix domain 182 212 1.2E-5 T 14-10-2018 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 SUPERFAMILY SSF100879 242 343 3.53E-22 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 Gene3D G3DSA:3.30.70.270 76 164 3.4E-25 T 14-10-2018 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 Gene3D G3DSA:1.10.150.20 165 236 3.9E-28 T 14-10-2018 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 Gene3D G3DSA:3.30.1490.100 240 345 2.9E-20 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 Hamap MF_01113 DNA polymerase IV [dinB]. 3 345 29.122 T 14-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 SUPERFAMILY SSF56672 5 235 1.51E-65 T 14-10-2018 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 Gene3D G3DSA:2.30.40.20 14 75 2.9E-28 T 14-10-2018 A4R43_37350 55115c7b831abd4abe131dae222ecb67 345 Pfam PF00817 impB/mucB/samB family 9 152 1.3E-38 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4R43_07815 0f75e1d0f83220a0ad9dc1f9b1c42a14 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 7.7E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_07815 0f75e1d0f83220a0ad9dc1f9b1c42a14 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 7.7E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_07815 0f75e1d0f83220a0ad9dc1f9b1c42a14 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 7.7E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_07815 0f75e1d0f83220a0ad9dc1f9b1c42a14 111 SMART SM00418 21 99 5.1E-27 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_07815 0f75e1d0f83220a0ad9dc1f9b1c42a14 111 Gene3D G3DSA:1.10.10.10 7 110 3.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07815 0f75e1d0f83220a0ad9dc1f9b1c42a14 111 SUPERFAMILY SSF46785 8 102 8.11E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07815 0f75e1d0f83220a0ad9dc1f9b1c42a14 111 Pfam PF12840 Helix-turn-helix domain 22 78 1.1E-12 T 14-10-2018 A4R43_07375 fe5e0cfd140b5e3c3e9af4af94c9f4a0 470 SUPERFAMILY SSF51905 2 469 1.47E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07375 fe5e0cfd140b5e3c3e9af4af94c9f4a0 470 Pfam PF00890 FAD binding domain 6 453 1.8E-61 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_07375 fe5e0cfd140b5e3c3e9af4af94c9f4a0 470 Gene3D G3DSA:3.90.700.10 245 408 2.6E-110 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_07375 fe5e0cfd140b5e3c3e9af4af94c9f4a0 470 Gene3D G3DSA:3.50.50.60 6 467 2.6E-110 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07375 fe5e0cfd140b5e3c3e9af4af94c9f4a0 470 SUPERFAMILY SSF56425 248 404 8.58E-24 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_07375 fe5e0cfd140b5e3c3e9af4af94c9f4a0 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.5E-6 T 14-10-2018 A4R43_07375 fe5e0cfd140b5e3c3e9af4af94c9f4a0 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 416 438 1.5E-6 T 14-10-2018 A4R43_03660 ba6641978f2386e6c708374d7a213d5d 201 SUPERFAMILY SSF48498 80 189 4.45E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_03660 ba6641978f2386e6c708374d7a213d5d 201 SUPERFAMILY SSF46689 3 82 1.9E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03660 ba6641978f2386e6c708374d7a213d5d 201 Gene3D G3DSA:1.10.357.10 7 195 4.0E-32 T 14-10-2018 A4R43_03660 ba6641978f2386e6c708374d7a213d5d 201 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 83 192 1.3E-12 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_03660 ba6641978f2386e6c708374d7a213d5d 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 6.6E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32315 b04796855c263472908bdecf58c4f3bc 208 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 62 3.6E-11 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_32315 b04796855c263472908bdecf58c4f3bc 208 Gene3D G3DSA:1.20.120.450 2 81 2.1E-11 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_32315 b04796855c263472908bdecf58c4f3bc 208 SUPERFAMILY SSF109854 5 127 3.85E-16 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_32315 b04796855c263472908bdecf58c4f3bc 208 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 189 7.3E-31 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_06005 70a39fcc9d1d36d2c7f5c9671ad224fe 129 SUPERFAMILY SSF110857 4 71 1.96E-8 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily A4R43_06005 70a39fcc9d1d36d2c7f5c9671ad224fe 129 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 66 1.3E-4 T 14-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like A4R43_06005 70a39fcc9d1d36d2c7f5c9671ad224fe 129 Gene3D G3DSA:3.10.490.10 1 129 1.2E-35 T 14-10-2018 A4R43_07060 a8317c66a8ebee790672f6de6a73790f 287 SUPERFAMILY SSF51735 2 152 1.09E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07060 a8317c66a8ebee790672f6de6a73790f 287 Gene3D G3DSA:1.10.1040.10 160 287 3.2E-41 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_07060 a8317c66a8ebee790672f6de6a73790f 287 SUPERFAMILY SSF48179 175 286 5.1E-6 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_07060 a8317c66a8ebee790672f6de6a73790f 287 Gene3D G3DSA:3.40.50.720 2 159 4.6E-38 T 14-10-2018 A4R43_07060 a8317c66a8ebee790672f6de6a73790f 287 PIRSF PIRSF000103 1 287 1.4E-38 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_07060 a8317c66a8ebee790672f6de6a73790f 287 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 152 2.0E-19 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_36025 56c4da947c110c93825cd45279d647b2 427 SUPERFAMILY SSF63411 227 422 5.1E-23 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4R43_36025 56c4da947c110c93825cd45279d647b2 427 Gene3D G3DSA:3.30.830.10 226 423 3.8E-34 T 14-10-2018 A4R43_36025 56c4da947c110c93825cd45279d647b2 427 Gene3D G3DSA:3.30.830.10 2 224 1.9E-58 T 14-10-2018 A4R43_36025 56c4da947c110c93825cd45279d647b2 427 Pfam PF00675 Insulinase (Peptidase family M16) 16 131 2.6E-19 T 14-10-2018 IPR011765 Peptidase M16, N-terminal A4R43_36025 56c4da947c110c93825cd45279d647b2 427 Pfam PF05193 Peptidase M16 inactive domain 172 352 1.1E-22 T 14-10-2018 IPR007863 Peptidase M16, C-terminal A4R43_36025 56c4da947c110c93825cd45279d647b2 427 SUPERFAMILY SSF63411 3 222 9.07E-48 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4R43_28030 b49051749e9f4b3c5c0d4c6c71390483 155 Gene3D G3DSA:1.10.10.10 8 154 2.1E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28030 b49051749e9f4b3c5c0d4c6c71390483 155 Pfam PF12802 MarR family 39 100 2.6E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_28030 b49051749e9f4b3c5c0d4c6c71390483 155 SUPERFAMILY SSF46785 5 152 1.7E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_28030 b49051749e9f4b3c5c0d4c6c71390483 155 SMART SM00347 34 137 6.1E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_28030 b49051749e9f4b3c5c0d4c6c71390483 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 7.5E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_28030 b49051749e9f4b3c5c0d4c6c71390483 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 7.5E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_28030 b49051749e9f4b3c5c0d4c6c71390483 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 127 147 7.5E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_28030 b49051749e9f4b3c5c0d4c6c71390483 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 7.5E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 2.0E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 2.0E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 Gene3D G3DSA:1.20.120.530 150 287 1.2E-16 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 SUPERFAMILY SSF46785 2 82 3.16E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 SUPERFAMILY SSF48008 153 282 2.62E-16 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 Gene3D G3DSA:1.10.10.10 3 100 8.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 SMART SM00345 10 68 2.9E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 Pfam PF07729 FCD domain 156 280 1.2E-12 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 2.7E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02100 febd658f6a1e08cd89cd0d9d61323f98 290 SMART SM00895 156 281 4.8E-9 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_12040 ac030343ecfb56b35ef17fc3a2d346eb 382 Gene3D G3DSA:1.20.1250.20 2 372 6.6E-42 T 14-10-2018 A4R43_12040 ac030343ecfb56b35ef17fc3a2d346eb 382 Pfam PF07690 Major Facilitator Superfamily 10 319 3.3E-34 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_12040 ac030343ecfb56b35ef17fc3a2d346eb 382 SUPERFAMILY SSF103473 3 373 1.26E-50 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_30920 da7ad3a3bf109aa0c4fc56a8294bc568 233 Pfam PF00005 ABC transporter 30 177 9.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_30920 da7ad3a3bf109aa0c4fc56a8294bc568 233 Gene3D G3DSA:3.40.50.300 11 229 1.1E-60 T 14-10-2018 A4R43_30920 da7ad3a3bf109aa0c4fc56a8294bc568 233 SMART SM00382 38 233 8.2E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_30920 da7ad3a3bf109aa0c4fc56a8294bc568 233 SUPERFAMILY SSF52540 14 227 1.05E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30920 da7ad3a3bf109aa0c4fc56a8294bc568 233 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_08205 844d0c8ad4e5f5ccf39cb520de4ef048 231 Gene3D G3DSA:3.40.50.300 6 227 7.2E-53 T 14-10-2018 A4R43_08205 844d0c8ad4e5f5ccf39cb520de4ef048 231 Pfam PF00005 ABC transporter 27 172 1.2E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_08205 844d0c8ad4e5f5ccf39cb520de4ef048 231 SMART SM00382 35 218 2.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08205 844d0c8ad4e5f5ccf39cb520de4ef048 231 SUPERFAMILY SSF52540 24 219 1.96E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08205 844d0c8ad4e5f5ccf39cb520de4ef048 231 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_32380 f415e1c79cbc324a3c720d8c3502d977 106 SMART SM00418 10 100 7.6E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_32380 f415e1c79cbc324a3c720d8c3502d977 106 Pfam PF12840 Helix-turn-helix domain 10 64 2.2E-11 T 14-10-2018 A4R43_32380 f415e1c79cbc324a3c720d8c3502d977 106 Gene3D G3DSA:1.10.10.10 5 95 3.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32380 f415e1c79cbc324a3c720d8c3502d977 106 SUPERFAMILY SSF46785 7 88 4.24E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_27065 90f6a71bc6db689a602030bb57cf89d9 321 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 203 220 - T 14-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 A4R43_27065 90f6a71bc6db689a602030bb57cf89d9 321 SUPERFAMILY SSF53697 27 267 6.49E-62 T 14-10-2018 A4R43_27065 90f6a71bc6db689a602030bb57cf89d9 321 SUPERFAMILY SSF46934 254 296 1.21E-5 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 A4R43_27065 90f6a71bc6db689a602030bb57cf89d9 321 Pfam PF13580 SIS domain 65 179 2.3E-7 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_27065 90f6a71bc6db689a602030bb57cf89d9 321 Gene3D G3DSA:1.10.8.1080 237 315 3.0E-23 T 14-10-2018 A4R43_27065 90f6a71bc6db689a602030bb57cf89d9 321 Gene3D G3DSA:3.40.50.10490 23 236 2.5E-70 T 14-10-2018 A4R43_27065 90f6a71bc6db689a602030bb57cf89d9 321 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 21 313 35.201 T 14-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 Pfam PF00366 Ribosomal protein S17 22 89 5.4E-29 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 Gene3D G3DSA:2.40.50.140 16 95 9.2E-32 T 14-10-2018 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 ProSitePatterns PS00056 Ribosomal protein S17 signature. 68 80 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 SUPERFAMILY SSF50249 17 94 2.31E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 17 88 6.0E-30 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 PRINTS PR00973 Ribosomal protein S17 family signature 78 85 1.3E-10 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 PRINTS PR00973 Ribosomal protein S17 family signature 36 59 1.3E-10 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 PRINTS PR00973 Ribosomal protein S17 family signature 68 78 1.3E-10 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 17 88 3.8E-33 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33885 a2b182f68743492e53182246dc6a24b3 95 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 17 92 23.274 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_25360 04c463e5cd93ff64e5f9e898268a0fb9 402 Gene3D G3DSA:1.20.1250.20 5 394 6.4E-31 T 14-10-2018 A4R43_25360 04c463e5cd93ff64e5f9e898268a0fb9 402 Pfam PF05977 Transmembrane secretion effector 19 383 3.9E-17 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_25360 04c463e5cd93ff64e5f9e898268a0fb9 402 SUPERFAMILY SSF103473 10 396 1.83E-36 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_31560 fefb5aca9b84d18e6d613ad9e876ea45 490 SUPERFAMILY SSF103473 5 483 4.19E-68 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_31560 fefb5aca9b84d18e6d613ad9e876ea45 490 Gene3D G3DSA:1.20.1720.10 12 253 3.0E-43 T 14-10-2018 A4R43_31560 fefb5aca9b84d18e6d613ad9e876ea45 490 Pfam PF07690 Major Facilitator Superfamily 20 406 9.0E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_31560 fefb5aca9b84d18e6d613ad9e876ea45 490 Gene3D G3DSA:1.20.1250.20 256 471 1.1E-16 T 14-10-2018 A4R43_02780 ea8d3df6f8c4983e61a6ea1517471fd5 165 Gene3D G3DSA:2.40.480.10 42 160 5.3E-9 T 14-10-2018 IPR034871 Allene oxide cyclase superfamily GO:0009695|GO:0046423 KEGG: 00592+5.3.99.6|MetaCyc: PWY-735 A4R43_02780 ea8d3df6f8c4983e61a6ea1517471fd5 165 SUPERFAMILY SSF141493 59 156 3.92E-5 T 14-10-2018 IPR034871 Allene oxide cyclase superfamily GO:0009695|GO:0046423 KEGG: 00592+5.3.99.6|MetaCyc: PWY-735 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 SMART SM01043 93 235 6.7E-52 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 72 7.5E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 Gene3D G3DSA:1.10.10.10 1 89 1.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 SMART SM00862 16 86 1.2E-5 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 SUPERFAMILY SSF52540 245 514 4.51E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 SUPERFAMILY SSF46894 5 86 1.47E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 Gene3D G3DSA:1.25.40.10 91 255 5.3E-51 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 Gene3D G3DSA:1.25.40.10 738 1011 2.0E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 PRINTS PR00364 Disease resistance protein signature 274 289 9.1E-6 T 14-10-2018 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 PRINTS PR00364 Disease resistance protein signature 449 463 9.1E-6 T 14-10-2018 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 PRINTS PR00364 Disease resistance protein signature 343 357 9.1E-6 T 14-10-2018 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 SUPERFAMILY SSF48452 752 896 1.19E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 SUPERFAMILY SSF48452 88 252 2.02E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28325 4ec136b89ad7134692bc2e132612e61a 1026 Pfam PF03704 Bacterial transcriptional activator domain 93 235 1.3E-42 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 Gene3D G3DSA:1.20.140.160 88 242 3.7E-46 T 14-10-2018 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 SUPERFAMILY SSF88946 3 89 1.31E-26 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 17 239 1.5E-83 T 14-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 209 235 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 PRINTS PR00046 Major sigma-70 factor signature 224 235 1.9E-13 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 PRINTS PR00046 Major sigma-70 factor signature 44 57 1.9E-13 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 PRINTS PR00046 Major sigma-70 factor signature 192 204 1.9E-13 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 PRINTS PR00046 Major sigma-70 factor signature 209 224 1.9E-13 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 Gene3D G3DSA:1.10.1740.10 3 86 7.1E-30 T 14-10-2018 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 Pfam PF04539 Sigma-70 region 3 99 173 2.8E-9 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 SUPERFAMILY SSF88659 156 241 2.24E-23 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 Pfam PF04545 Sigma-70, region 4 188 237 5.9E-18 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 44 57 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 SUPERFAMILY SSF88659 90 167 1.26E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 PIRSF PIRSF000770 6 244 2.0E-58 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 Pfam PF04542 Sigma-70 region 2 17 89 1.3E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_18405 6a7fb225ef0c88333bfbb9a5f4fef233 245 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 239 1.3E-35 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 PIRSF PIRSF016578 1 352 1.2E-14 T 14-10-2018 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 Gene3D G3DSA:2.40.110.10 107 231 1.1E-19 T 14-10-2018 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 SUPERFAMILY SSF56645 9 226 2.88E-44 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 Gene3D G3DSA:1.20.140.10 232 365 1.3E-17 T 14-10-2018 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 109 214 5.0E-12 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 SUPERFAMILY SSF47203 241 363 1.32E-17 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 Gene3D G3DSA:1.10.540.10 4 105 1.5E-21 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 364 1.3E-12 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_37145 5f42ca7ba6f4c779132c8ebd5b6cc51e 368 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 104 3.6E-15 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_23480 48a5cc5414200e7286f699d119382f37 347 SUPERFAMILY SSF51430 1 318 3.14E-104 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_23480 48a5cc5414200e7286f699d119382f37 347 Gene3D G3DSA:3.20.20.100 1 339 7.4E-130 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_23480 48a5cc5414200e7286f699d119382f37 347 PRINTS PR00069 Aldo-keto reductase signature 111 129 6.1E-6 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_23480 48a5cc5414200e7286f699d119382f37 347 PRINTS PR00069 Aldo-keto reductase signature 47 71 6.1E-6 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_23480 48a5cc5414200e7286f699d119382f37 347 PRINTS PR00069 Aldo-keto reductase signature 142 159 6.1E-6 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_23480 48a5cc5414200e7286f699d119382f37 347 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 142 159 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A4R43_23480 48a5cc5414200e7286f699d119382f37 347 Pfam PF00248 Aldo/keto reductase family 16 316 7.0E-77 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_34210 c73c5b941931c038d50c470102de7657 368 SUPERFAMILY SSF53474 46 348 3.48E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_34210 c73c5b941931c038d50c470102de7657 368 Gene3D G3DSA:3.40.50.1820 51 351 1.8E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_34210 c73c5b941931c038d50c470102de7657 368 Pfam PF12697 Alpha/beta hydrolase family 82 340 1.9E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 53 73 3.5E-27 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 146 169 3.5E-27 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 97 113 3.5E-27 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 192 213 3.5E-27 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 223 247 3.5E-27 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 75 91 3.5E-27 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 SUPERFAMILY SSF56655 18 272 8.9E-53 T 14-10-2018 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 Gene3D G3DSA:3.40.190.80 164 274 4.6E-14 T 14-10-2018 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 Gene3D G3DSA:3.30.540.10 9 155 3.5E-35 T 14-10-2018 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 Pfam PF00459 Inositol monophosphatase family 19 266 1.2E-47 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_33055 2c96ea68cfe050be56e708a13f58b788 280 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 226 240 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 Gene3D G3DSA:3.30.70.260 348 419 1.1E-143 T 14-10-2018 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 Gene3D G3DSA:3.30.360.10 136 347 1.1E-143 T 14-10-2018 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 Pfam PF01842 ACT domain 355 415 1.5E-11 T 14-10-2018 IPR002912 ACT domain A4R43_22455 fee0db21618fc93e280e0343225285d9 433 PIRSF PIRSF000098 3 431 1.0E-155 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 SUPERFAMILY SSF55347 137 307 4.64E-50 T 14-10-2018 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 SUPERFAMILY SSF51735 4 158 3.67E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22455 fee0db21618fc93e280e0343225285d9 433 SUPERFAMILY SSF55021 350 423 5.09E-13 T 14-10-2018 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 Pfam PF00742 Homoserine dehydrogenase 137 320 2.1E-65 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 Gene3D G3DSA:3.40.50.720 6 339 1.1E-143 T 14-10-2018 A4R43_22455 fee0db21618fc93e280e0343225285d9 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 129 1.7E-24 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A4R43_16090 5f494dd906f7256e40da7e270af168cf 312 SUPERFAMILY SSF54637 18 174 1.33E-20 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_16090 5f494dd906f7256e40da7e270af168cf 312 Gene3D G3DSA:3.10.129.10 4 179 2.7E-62 T 14-10-2018 A4R43_16090 5f494dd906f7256e40da7e270af168cf 312 Pfam PF13452 N-terminal half of MaoC dehydratase 26 158 5.1E-19 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 A4R43_16090 5f494dd906f7256e40da7e270af168cf 312 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 234 296 2.4E-21 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A4R43_16090 5f494dd906f7256e40da7e270af168cf 312 SUPERFAMILY SSF50249 177 305 7.37E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_35940 52b56858c91bfeb59d688b9cd7525dcf 266 SUPERFAMILY SSF69618 6 264 9.55E-54 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_35940 52b56858c91bfeb59d688b9cd7525dcf 266 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 257 3.8E-40 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_35940 52b56858c91bfeb59d688b9cd7525dcf 266 Gene3D G3DSA:3.40.50.10090 37 168 2.5E-65 T 14-10-2018 A4R43_35940 52b56858c91bfeb59d688b9cd7525dcf 266 Gene3D G3DSA:3.40.50.10090 11 256 2.5E-65 T 14-10-2018 A4R43_11240 eb20c342b003eef29080c7e832834715 210 Gene3D G3DSA:1.10.357.10 67 208 2.5E-15 T 14-10-2018 A4R43_11240 eb20c342b003eef29080c7e832834715 210 SUPERFAMILY SSF46689 17 92 4.1E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11240 eb20c342b003eef29080c7e832834715 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 9.7E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11240 eb20c342b003eef29080c7e832834715 210 SUPERFAMILY SSF48498 96 205 1.51E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11240 eb20c342b003eef29080c7e832834715 210 Gene3D G3DSA:1.10.10.60 14 66 8.8E-13 T 14-10-2018 A4R43_08400 80034d04aa5f5108a435d857a5b01fb2 218 SUPERFAMILY SSF53955 31 104 5.81E-26 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_08400 80034d04aa5f5108a435d857a5b01fb2 218 Pfam PF01471 Putative peptidoglycan binding domain 160 210 5.7E-8 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_08400 80034d04aa5f5108a435d857a5b01fb2 218 Gene3D G3DSA:1.10.101.10 141 217 3.2E-10 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_08400 80034d04aa5f5108a435d857a5b01fb2 218 Gene3D G3DSA:1.10.530.10 10 108 8.3E-29 T 14-10-2018 A4R43_08400 80034d04aa5f5108a435d857a5b01fb2 218 SUPERFAMILY SSF47090 144 210 3.66E-9 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_08400 80034d04aa5f5108a435d857a5b01fb2 218 Pfam PF06737 Transglycosylase-like domain 32 101 6.7E-21 T 14-10-2018 IPR010618 Transglycosylase-like A4R43_10915 4a45ca5cab537042f4b3653e08b4d4df 288 Pfam PF12740 Chlorophyllase enzyme 68 185 4.7E-7 T 14-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 A4R43_10915 4a45ca5cab537042f4b3653e08b4d4df 288 Gene3D G3DSA:3.40.50.1820 22 287 1.8E-84 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_10915 4a45ca5cab537042f4b3653e08b4d4df 288 SUPERFAMILY SSF53474 37 277 2.49E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06535 1fc8c9e0514bfc49f20210254f574a47 138 Gene3D G3DSA:1.10.10.10 6 137 4.5E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06535 1fc8c9e0514bfc49f20210254f574a47 138 SUPERFAMILY SSF46785 5 135 6.39E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06535 1fc8c9e0514bfc49f20210254f574a47 138 Pfam PF12802 MarR family 25 82 5.4E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06535 1fc8c9e0514bfc49f20210254f574a47 138 SMART SM00347 19 118 1.5E-4 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_08495 b5cc620b595f2506d8e16e10db1f21cb 265 Gene3D G3DSA:3.40.50.720 9 243 4.8E-48 T 14-10-2018 A4R43_08495 b5cc620b595f2506d8e16e10db1f21cb 265 Pfam PF13460 NAD(P)H-binding 10 165 1.1E-7 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_08495 b5cc620b595f2506d8e16e10db1f21cb 265 Gene3D G3DSA:3.90.25.10 117 245 4.8E-48 T 14-10-2018 A4R43_08495 b5cc620b595f2506d8e16e10db1f21cb 265 SUPERFAMILY SSF51735 5 254 2.99E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22325 5dd619ead3f4824c3fb694f81b3f6afa 425 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 407 4.1E-96 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A4R43_22325 5dd619ead3f4824c3fb694f81b3f6afa 425 SUPERFAMILY SSF55205 4 417 1.96E-126 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4R43_22325 5dd619ead3f4824c3fb694f81b3f6afa 425 Gene3D G3DSA:3.65.10.10 21 230 1.8E-150 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A4R43_22325 5dd619ead3f4824c3fb694f81b3f6afa 425 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 416 2.3E-159 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_22325 5dd619ead3f4824c3fb694f81b3f6afa 425 Gene3D G3DSA:3.65.10.10 7 415 1.8E-150 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A4R43_22325 5dd619ead3f4824c3fb694f81b3f6afa 425 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 417 39.044 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 Pfam PF00005 ABC transporter 21 178 5.9E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 Pfam PF00005 ABC transporter 290 440 1.4E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 SUPERFAMILY SSF52540 272 512 8.91E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 273 0.0012 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 492 520 1.5E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 SMART SM00382 298 490 2.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 SMART SM00382 29 228 3.7E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 Gene3D G3DSA:3.40.50.300 1 273 1.3E-75 T 14-10-2018 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 Gene3D G3DSA:3.40.50.300 274 525 4.4E-82 T 14-10-2018 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_04410 dcbd120a9602e93d7d10b5d5073f7a80 526 SUPERFAMILY SSF52540 9 250 2.77E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_02420 43e5a429563167e60fa4ecaa095f32a2 326 SUPERFAMILY SSF51430 1 321 9.82E-104 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_02420 43e5a429563167e60fa4ecaa095f32a2 326 Pfam PF00248 Aldo/keto reductase family 15 315 6.1E-78 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_02420 43e5a429563167e60fa4ecaa095f32a2 326 Gene3D G3DSA:3.20.20.100 1 324 2.1E-121 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_21345 9840dfc2516faa65f45a70c9875f0539 378 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 268 309 - T 14-10-2018 IPR035595 UDP-glycosyltransferase family, conserved site Reactome: R-HSA-156588 A4R43_21345 9840dfc2516faa65f45a70c9875f0539 378 SUPERFAMILY SSF53756 1 369 8.57E-60 T 14-10-2018 A4R43_21345 9840dfc2516faa65f45a70c9875f0539 378 Gene3D G3DSA:3.40.50.2000 195 358 4.0E-80 T 14-10-2018 A4R43_21345 9840dfc2516faa65f45a70c9875f0539 378 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 262 326 8.5E-11 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 A4R43_21345 9840dfc2516faa65f45a70c9875f0539 378 Gene3D G3DSA:3.40.50.2000 1 369 4.0E-80 T 14-10-2018 A4R43_06635 6878fb3095b7e8615d8909921762d198 213 SUPERFAMILY SSF46689 10 91 4.62E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_06635 6878fb3095b7e8615d8909921762d198 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.2E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06635 6878fb3095b7e8615d8909921762d198 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 5.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06635 6878fb3095b7e8615d8909921762d198 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 5.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06635 6878fb3095b7e8615d8909921762d198 213 SUPERFAMILY SSF48498 87 212 1.56E-35 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_06635 6878fb3095b7e8615d8909921762d198 213 Gene3D G3DSA:1.10.357.10 17 213 1.3E-66 T 14-10-2018 A4R43_30245 2cbd15b95b6659044563450e6f1d1783 318 Pfam PF01464 Transglycosylase SLT domain 57 174 7.7E-6 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 A4R43_30245 2cbd15b95b6659044563450e6f1d1783 318 SUPERFAMILY SSF54001 195 300 9.32E-37 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_30245 2cbd15b95b6659044563450e6f1d1783 318 Gene3D G3DSA:1.10.530.10 43 190 2.6E-15 T 14-10-2018 A4R43_30245 2cbd15b95b6659044563450e6f1d1783 318 Gene3D G3DSA:3.90.1720.10 191 314 1.4E-37 T 14-10-2018 A4R43_30245 2cbd15b95b6659044563450e6f1d1783 318 Pfam PF00877 NlpC/P60 family 204 300 6.0E-25 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_30245 2cbd15b95b6659044563450e6f1d1783 318 SUPERFAMILY SSF53955 41 173 1.01E-18 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Pfam PF04560 RNA polymerase Rpb2, domain 7 1054 1128 9.1E-27 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Gene3D G3DSA:3.90.1800.10 1039 1093 1.7E-10 T 14-10-2018 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Gene3D G3DSA:2.40.50.150 747 873 0.0 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Gene3D G3DSA:3.90.1100.10 40 636 0.0 T 14-10-2018 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 35 1130 12.312 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Pfam PF00562 RNA polymerase Rpb2, domain 6 636 1052 3.4E-159 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Gene3D G3DSA:2.30.150.10 512 579 0.0 T 14-10-2018 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Gene3D G3DSA:2.40.270.10 38 1030 0.0 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 SUPERFAMILY SSF64484 34 1141 0.0 T 14-10-2018 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Pfam PF10385 RNA polymerase beta subunit external 1 domain 509 575 3.0E-26 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Gene3D G3DSA:3.90.1110.10 182 366 0.0 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Pfam PF04563 RNA polymerase beta subunit 49 416 5.1E-23 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Pfam PF04565 RNA polymerase Rpb2, domain 3 431 499 1.5E-28 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 251 849 0.0 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 ProSitePatterns PS01166 RNA polymerases beta chain signature. 875 887 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Pfam PF04561 RNA polymerase Rpb2, domain 2 177 372 8.5E-28 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4R43_33650 91b6b8c8ed862dd950508c263f791671 1169 Gene3D G3DSA:2.40.50.100 637 711 0.0 T 14-10-2018 A4R43_18005 64905c964a06cec1a36866c126c57b0b 265 SUPERFAMILY SSF51735 3 256 1.11E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_18005 64905c964a06cec1a36866c126c57b0b 265 Gene3D G3DSA:3.90.25.10 117 248 4.7E-61 T 14-10-2018 A4R43_18005 64905c964a06cec1a36866c126c57b0b 265 Gene3D G3DSA:3.40.50.720 6 246 4.7E-61 T 14-10-2018 A4R43_18005 64905c964a06cec1a36866c126c57b0b 265 Pfam PF13460 NAD(P)H-binding 9 68 1.1E-9 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_25745 320796b044abceb608408591a0a3a0d2 267 Gene3D G3DSA:3.40.1280.10 110 265 3.1E-46 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_25745 320796b044abceb608408591a0a3a0d2 267 SUPERFAMILY SSF55315 6 105 2.82E-11 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like A4R43_25745 320796b044abceb608408591a0a3a0d2 267 Pfam PF00588 SpoU rRNA Methylase family 122 261 1.3E-30 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4R43_25745 320796b044abceb608408591a0a3a0d2 267 SUPERFAMILY SSF75217 99 263 1.05E-39 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_13445 c356d6b9a02eb697da85a4c023e48eb4 195 SUPERFAMILY SSF48498 80 194 1.29E-15 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_13445 c356d6b9a02eb697da85a4c023e48eb4 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.1E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13445 c356d6b9a02eb697da85a4c023e48eb4 195 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 83 193 4.3E-8 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_13445 c356d6b9a02eb697da85a4c023e48eb4 195 Gene3D G3DSA:1.10.357.10 1 191 4.7E-46 T 14-10-2018 A4R43_13445 c356d6b9a02eb697da85a4c023e48eb4 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 5.9E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13445 c356d6b9a02eb697da85a4c023e48eb4 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 5.9E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13445 c356d6b9a02eb697da85a4c023e48eb4 195 SUPERFAMILY SSF46689 3 73 1.08E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 Gene3D G3DSA:3.40.190.10 84 273 1.9E-26 T 14-10-2018 A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 Gene3D G3DSA:1.10.10.10 1 77 7.2E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 Gene3D G3DSA:3.40.190.10 156 260 1.9E-26 T 14-10-2018 A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 Pfam PF03466 LysR substrate binding domain 82 283 1.5E-26 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 11 22 4.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 4.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 32 4.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 55 8.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 SUPERFAMILY SSF46785 2 75 1.4E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_21585 8587e04890a01fd7ab014190b5a3958c 309 SUPERFAMILY SSF53850 84 287 7.06E-27 T 14-10-2018 A4R43_11030 c114ac5fe9ffd5d68bc1335c16ea700d 131 Pfam PF12680 SnoaL-like domain 12 115 8.9E-13 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_11030 c114ac5fe9ffd5d68bc1335c16ea700d 131 Gene3D G3DSA:3.10.450.50 3 131 3.6E-29 T 14-10-2018 A4R43_11030 c114ac5fe9ffd5d68bc1335c16ea700d 131 SUPERFAMILY SSF54427 3 128 2.77E-25 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_35415 11a6e2d689a1389672a3ede6e0fd7d90 330 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 321 1.0E-132 T 14-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A4R43_35415 11a6e2d689a1389672a3ede6e0fd7d90 330 SUPERFAMILY SSF51735 1 322 1.34E-98 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_35415 11a6e2d689a1389672a3ede6e0fd7d90 330 Gene3D G3DSA:3.40.50.720 2 306 3.4E-123 T 14-10-2018 A4R43_35415 11a6e2d689a1389672a3ede6e0fd7d90 330 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 305 2.4E-80 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_35415 11a6e2d689a1389672a3ede6e0fd7d90 330 Gene3D G3DSA:3.90.25.10 193 314 3.4E-123 T 14-10-2018 A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 Pfam PF00072 Response regulator receiver domain 3 108 5.4E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 Gene3D G3DSA:3.40.50.12740 1 202 2.2E-43 T 14-10-2018 A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 SMART SM00448 1 120 2.7E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.9E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.9E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.9E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 SMART SM00421 146 208 1.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 SUPERFAMILY SSF52172 2 170 1.67E-18 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_27925 12ad9fddcfb6d989bb2b6ecf8cb7d97d 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 193 4.2E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 Gene3D G3DSA:3.40.47.10 264 407 4.5E-49 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 PIRSF PIRSF000447 8 420 1.3E-138 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 11 415 8.6E-150 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 Gene3D G3DSA:3.40.47.10 2 262 1.8E-75 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 254 5.5E-42 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 SMART SM00825 Beta-ketoacyl synthase 13 420 4.9E-14 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 SUPERFAMILY SSF53901 11 259 5.76E-62 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 SUPERFAMILY SSF53901 222 418 1.15E-64 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_12645 833ee9a8b93b56ca1509c5f04c6893ea 420 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 376 6.3E-36 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_08775 e39f0674ac24e687112d96eab080cf74 280 Gene3D G3DSA:3.20.20.30 1 270 6.8E-61 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_08775 e39f0674ac24e687112d96eab080cf74 280 SUPERFAMILY SSF51679 4 257 3.39E-49 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_08775 e39f0674ac24e687112d96eab080cf74 280 Pfam PF00296 Luciferase-like monooxygenase 15 211 2.0E-38 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_18400 41767f5edb4a30e91ec49f29b726964d 163 Gene3D G3DSA:2.70.70.10 9 150 2.1E-21 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_18400 41767f5edb4a30e91ec49f29b726964d 163 SUPERFAMILY SSF51261 17 148 9.42E-18 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_18400 41767f5edb4a30e91ec49f29b726964d 163 Pfam PF01551 Peptidase family M23 51 145 3.0E-15 T 14-10-2018 IPR016047 Peptidase M23 A4R43_30990 a202437a722cae8b8ed7437d5475c52d 235 SUPERFAMILY SSF69318 28 209 1.01E-6 T 14-10-2018 A4R43_13415 c0765a72758a0ff5693f78c0332fe98b 231 Pfam PF00005 ABC transporter 20 155 3.6E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_13415 c0765a72758a0ff5693f78c0332fe98b 231 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_13415 c0765a72758a0ff5693f78c0332fe98b 231 SUPERFAMILY SSF52540 4 223 6.15E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13415 c0765a72758a0ff5693f78c0332fe98b 231 Gene3D G3DSA:3.40.50.300 2 230 7.9E-48 T 14-10-2018 A4R43_13415 c0765a72758a0ff5693f78c0332fe98b 231 SMART SM00382 28 189 3.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_06575 84f1be02922d8a608f0afd5c6518cb77 251 Gene3D G3DSA:3.40.50.150 43 246 1.1E-35 T 14-10-2018 A4R43_06575 84f1be02922d8a608f0afd5c6518cb77 251 SUPERFAMILY SSF53335 46 230 4.45E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_06575 84f1be02922d8a608f0afd5c6518cb77 251 Pfam PF13649 Methyltransferase domain 62 156 6.8E-18 T 14-10-2018 A4R43_39415 4f8f2aad9f4a09d1cd5f1e2c2b547ce1 104 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 8 93 2.8E-5 T 14-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 A4R43_07380 5b3b2421781fde799208c6d858fc57ae 435 SUPERFAMILY SSF103473 12 430 1.16E-79 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_07380 5b3b2421781fde799208c6d858fc57ae 435 Gene3D G3DSA:1.20.1250.20 17 221 3.3E-45 T 14-10-2018 A4R43_07380 5b3b2421781fde799208c6d858fc57ae 435 Pfam PF07690 Major Facilitator Superfamily 32 396 8.1E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_07380 5b3b2421781fde799208c6d858fc57ae 435 Gene3D G3DSA:1.20.1250.20 246 434 4.4E-26 T 14-10-2018 A4R43_28165 f2d4e50fbe529b46c6e52fe8ef4393d3 171 SUPERFAMILY SSF48317 20 166 1.2E-32 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4R43_28165 f2d4e50fbe529b46c6e52fe8ef4393d3 171 Gene3D G3DSA:1.20.144.10 90 171 2.6E-14 T 14-10-2018 A4R43_28165 f2d4e50fbe529b46c6e52fe8ef4393d3 171 Pfam PF01569 PAP2 superfamily 64 167 2.2E-16 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_28165 f2d4e50fbe529b46c6e52fe8ef4393d3 171 SMART SM00014 61 165 5.7E-7 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_11185 649e21a4c9eb12f1733e8b8af082871f 199 Gene3D G3DSA:1.10.357.10 3 190 1.1E-58 T 14-10-2018 A4R43_11185 649e21a4c9eb12f1733e8b8af082871f 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.5E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11185 649e21a4c9eb12f1733e8b8af082871f 199 SUPERFAMILY SSF46689 1 74 2.41E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_11185 649e21a4c9eb12f1733e8b8af082871f 199 SUPERFAMILY SSF48498 85 186 2.23E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11185 649e21a4c9eb12f1733e8b8af082871f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 5.5E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11185 649e21a4c9eb12f1733e8b8af082871f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 5.5E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_11185 649e21a4c9eb12f1733e8b8af082871f 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_00560 130473ee70487baeda479f04a84d9369 417 Pfam PF07394 Protein of unknown function (DUF1501) 244 408 1.4E-25 T 14-10-2018 IPR010869 Protein of unknown function DUF1501 A4R43_17185 096efb0ee67cc2f93dfbf71b4d50f3c5 270 SUPERFAMILY SSF159713 90 243 2.09E-18 T 14-10-2018 A4R43_17185 096efb0ee67cc2f93dfbf71b4d50f3c5 270 Gene3D G3DSA:3.40.50.11590 132 245 4.4E-7 T 14-10-2018 A4R43_17185 096efb0ee67cc2f93dfbf71b4d50f3c5 270 Pfam PF04016 Putative heavy-metal chelation 135 243 6.0E-12 T 14-10-2018 IPR007161 Putative heavy-metal chelation domain A4R43_12485 c0b37fc458ee38ed8d2bae65c52eddbe 274 Pfam PF13649 Methyltransferase domain 55 149 1.2E-31 T 14-10-2018 A4R43_12485 c0b37fc458ee38ed8d2bae65c52eddbe 274 Gene3D G3DSA:3.40.50.150 32 271 2.2E-48 T 14-10-2018 A4R43_12485 c0b37fc458ee38ed8d2bae65c52eddbe 274 SUPERFAMILY SSF53335 6 221 1.67E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_24745 c0088a06c62c968f3ac6961bca4f4c2e 372 SUPERFAMILY SSF55821 17 207 1.59E-60 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A4R43_24745 c0088a06c62c968f3ac6961bca4f4c2e 372 PIRSF PIRSF004930 9 336 8.2E-105 T 14-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A4R43_24745 c0088a06c62c968f3ac6961bca4f4c2e 372 Gene3D G3DSA:3.90.870.10 10 212 7.1E-79 T 14-10-2018 A4R43_24745 c0088a06c62c968f3ac6961bca4f4c2e 372 Pfam PF03481 Putative GTP-binding controlling metal-binding 199 330 1.7E-20 T 14-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A4R43_24745 c0088a06c62c968f3ac6961bca4f4c2e 372 Pfam PF01300 Telomere recombination 24 197 5.6E-57 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 A4R43_24745 c0088a06c62c968f3ac6961bca4f4c2e 372 Gene3D G3DSA:3.40.50.11030 213 339 1.8E-23 T 14-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A4R43_24745 c0088a06c62c968f3ac6961bca4f4c2e 372 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 17 206 1.9E-57 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 62 5.3E-5 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 43 5.3E-5 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 Pfam PF07729 FCD domain 82 208 6.0E-28 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 SUPERFAMILY SSF48008 79 211 1.18E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 Gene3D G3DSA:1.20.120.530 75 214 6.5E-32 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 68 1.1E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 SUPERFAMILY SSF46785 12 76 1.57E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 SMART SM00345 14 72 4.8E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 Gene3D G3DSA:1.10.10.10 3 73 3.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01790 07e35c44af34d2dd077b18d50e4be331 236 SMART SM00895 82 208 1.3E-21 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 Gene3D G3DSA:3.40.50.300 343 408 2.2E-9 T 14-10-2018 A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 SUPERFAMILY SSF52540 352 488 6.23E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 SUPERFAMILY SSF52540 9 237 1.96E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 Pfam PF00005 ABC transporter 19 184 7.9E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 Gene3D G3DSA:3.40.50.300 3 275 3.3E-65 T 14-10-2018 A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 Gene3D G3DSA:3.40.50.300 409 489 2.9E-11 T 14-10-2018 A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 Pfam PF12848 ABC transporter 223 274 7.6E-6 T 14-10-2018 IPR032781 ABC-transporter extension domain A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 SMART SM00382 28 229 8.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 SMART SM00382 364 486 8.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_10955 db1c92fa7601c9d3c3be7d564242de0b 490 Pfam PF00005 ABC transporter 360 391 1.9E-6 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_25850 2aab2d569ae3193736e18cf5101d8c2e 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 2.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25850 2aab2d569ae3193736e18cf5101d8c2e 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 2.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25850 2aab2d569ae3193736e18cf5101d8c2e 210 SUPERFAMILY SSF46689 17 96 1.04E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25850 2aab2d569ae3193736e18cf5101d8c2e 210 Gene3D G3DSA:1.10.357.10 14 202 8.6E-21 T 14-10-2018 A4R43_25850 2aab2d569ae3193736e18cf5101d8c2e 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 2.0E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21580 1900b313335063256bda3d53513da137 320 PIRSF PIRSF037196 2 314 8.1E-101 T 14-10-2018 IPR017133 Pyoverdine chromophore biosynthesis protein PvcA A4R43_21580 1900b313335063256bda3d53513da137 320 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 42 292 2.8E-73 T 14-10-2018 IPR007817 Pyoverdine biosynthesis A4R43_02520 b04a13134b4a3642efebef440439eed7 455 SUPERFAMILY SSF51445 4 450 4.29E-155 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_02520 b04a13134b4a3642efebef440439eed7 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 398 415 7.6E-22 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_02520 b04a13134b4a3642efebef440439eed7 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 287 301 7.6E-22 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_02520 b04a13134b4a3642efebef440439eed7 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 422 434 7.6E-22 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_02520 b04a13134b4a3642efebef440439eed7 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 360 368 7.6E-22 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_02520 b04a13134b4a3642efebef440439eed7 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 377 388 7.6E-22 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_02520 b04a13134b4a3642efebef440439eed7 455 TIGRFAM TIGR03356 BGL: beta-galactosidase 5 444 5.0E-175 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 A4R43_02520 b04a13134b4a3642efebef440439eed7 455 Gene3D G3DSA:3.20.20.80 1 454 1.9E-166 T 14-10-2018 A4R43_02520 b04a13134b4a3642efebef440439eed7 455 Pfam PF00232 Glycosyl hydrolase family 1 4 450 2.6E-153 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_02520 b04a13134b4a3642efebef440439eed7 455 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A4R43_09155 3a83cc7a8b982a9cfd1098ce169459a0 345 SUPERFAMILY SSF51679 11 342 7.65E-64 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_09155 3a83cc7a8b982a9cfd1098ce169459a0 345 Pfam PF00296 Luciferase-like monooxygenase 8 317 1.4E-77 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_09155 3a83cc7a8b982a9cfd1098ce169459a0 345 Gene3D G3DSA:3.20.20.30 4 341 8.9E-78 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_07570 451a04fd6b175a6ddf68a0cce8a7c52b 67 Pfam PF09360 Iron-binding zinc finger CDGSH type 15 59 5.9E-14 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 A4R43_07570 451a04fd6b175a6ddf68a0cce8a7c52b 67 SMART SM00704 20 64 2.2E-8 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 A4R43_07570 451a04fd6b175a6ddf68a0cce8a7c52b 67 Gene3D G3DSA:3.40.5.90 7 67 1.4E-9 T 14-10-2018 A4R43_09940 0e436e630a14ddbb07f5e4dbebba4e01 261 Pfam PF12697 Alpha/beta hydrolase family 25 251 7.5E-25 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09940 0e436e630a14ddbb07f5e4dbebba4e01 261 SUPERFAMILY SSF53474 10 254 2.66E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09940 0e436e630a14ddbb07f5e4dbebba4e01 261 Gene3D G3DSA:3.40.50.1820 9 259 1.1E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_11455 1429189d087d20bb0dd2d5d5e9c14b31 237 Gene3D G3DSA:3.60.15.10 17 237 7.6E-54 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_11455 1429189d087d20bb0dd2d5d5e9c14b31 237 SMART SM00849 27 203 1.6E-29 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_11455 1429189d087d20bb0dd2d5d5e9c14b31 237 Pfam PF00753 Metallo-beta-lactamase superfamily 28 203 1.5E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_11455 1429189d087d20bb0dd2d5d5e9c14b31 237 SUPERFAMILY SSF56281 26 223 2.17E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 257 1.4E-49 T 14-10-2018 A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 SUPERFAMILY SSF51735 7 258 3.66E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.3E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.3E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.3E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.1E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 6.1E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.1E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.1E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.1E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.1E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41620 06dc1f6a811995b58d7f97be279678c8 261 Gene3D G3DSA:3.40.50.720 3 260 5.0E-71 T 14-10-2018 A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 60 403 1.5E-86 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 409 551 4.8E-22 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 Gene3D G3DSA:3.40.50.1820 255 403 2.6E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 SUPERFAMILY SSF53474 50 380 9.41E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 Gene3D G3DSA:3.40.50.1820 26 245 2.8E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 SMART SM00939 346 529 6.5E-14 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 SUPERFAMILY SSF49785 340 491 2.76E-13 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 363 461 8.5E-6 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_01750 a7316fc6af13c0a9bb8a8673f1ce5e17 558 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 56 323 5.5E-54 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4R43_26345 c7d629b46f5f7726543f230fe807b8b8 554 Gene3D G3DSA:3.50.30.80 379 525 1.6E-48 T 14-10-2018 A4R43_26345 c7d629b46f5f7726543f230fe807b8b8 554 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 6 554 45.449 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_26345 c7d629b46f5f7726543f230fe807b8b8 554 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 20 552 6.8E-217 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_26345 c7d629b46f5f7726543f230fe807b8b8 554 Pfam PF00920 Dehydratase family 36 551 3.0E-211 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_26345 c7d629b46f5f7726543f230fe807b8b8 554 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_26345 c7d629b46f5f7726543f230fe807b8b8 554 SUPERFAMILY SSF143975 3 378 1.96E-139 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_26345 c7d629b46f5f7726543f230fe807b8b8 554 SUPERFAMILY SSF52016 379 553 1.57E-52 T 14-10-2018 A4R43_26345 c7d629b46f5f7726543f230fe807b8b8 554 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 463 474 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 62 8.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 144 4.0E-5 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 Gene3D G3DSA:1.10.10.60 219 279 1.1E-10 T 14-10-2018 A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 SUPERFAMILY SSF48498 78 206 1.56E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 SUPERFAMILY SSF48498 292 407 9.67E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 SUPERFAMILY SSF46689 222 278 6.67E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 SUPERFAMILY SSF46689 10 69 1.09E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 Gene3D G3DSA:1.10.357.10 2 217 1.4E-33 T 14-10-2018 A4R43_07775 e5ec0cc168997bb7d9928def48b12a0e 412 Gene3D G3DSA:1.10.357.10 280 412 1.6E-11 T 14-10-2018 A4R43_17100 b69d1f86d657641c4edaa9bb48544ce7 503 Gene3D G3DSA:3.30.479.30 79 193 5.5E-25 T 14-10-2018 A4R43_17100 b69d1f86d657641c4edaa9bb48544ce7 503 SMART SM00244 28 203 0.0013 T 14-10-2018 IPR001107 Band 7 domain A4R43_17100 b69d1f86d657641c4edaa9bb48544ce7 503 SUPERFAMILY SSF117892 70 207 1.28E-25 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily A4R43_17100 b69d1f86d657641c4edaa9bb48544ce7 503 Pfam PF01145 SPFH domain / Band 7 family 32 218 7.6E-20 T 14-10-2018 IPR001107 Band 7 domain A4R43_17100 b69d1f86d657641c4edaa9bb48544ce7 503 Pfam PF15975 Flotillin 379 480 1.4E-10 T 14-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 A4R43_38120 2bf99a4b5277697dadf545f34b43854c 334 Gene3D G3DSA:3.20.20.140 95 333 1.3E-65 T 14-10-2018 A4R43_38120 2bf99a4b5277697dadf545f34b43854c 334 SUPERFAMILY SSF89550 99 328 6.8E-48 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4R43_38120 2bf99a4b5277697dadf545f34b43854c 334 SMART SM00481 100 179 1.2E-16 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A4R43_38120 2bf99a4b5277697dadf545f34b43854c 334 PIRSF PIRSF036978 1 334 1.5E-147 T 14-10-2018 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 A4R43_38120 2bf99a4b5277697dadf545f34b43854c 334 Pfam PF14716 Helix-hairpin-helix domain 4 69 4.7E-14 T 14-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain A4R43_38120 2bf99a4b5277697dadf545f34b43854c 334 SUPERFAMILY SSF47802 3 82 2.62E-12 T 14-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily A4R43_38120 2bf99a4b5277697dadf545f34b43854c 334 Gene3D G3DSA:1.10.150.110 1 82 3.3E-12 T 14-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily A4R43_30420 43d32e8b4469da6b396664b569491e41 296 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 163 273 8.1E-23 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 Gene3D G3DSA:1.10.1040.10 163 293 8.0E-47 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 SUPERFAMILY SSF48179 161 292 5.44E-39 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 152 180 7.4E-17 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 2 25 7.4E-17 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 227 254 7.4E-17 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 SMART SM01350 163 296 1.7E-4 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 231 243 - T 14-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 144 2.6E-34 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 3 294 1.5E-103 T 14-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 A4R43_30420 43d32e8b4469da6b396664b569491e41 296 SUPERFAMILY SSF51735 3 145 5.39E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_30420 43d32e8b4469da6b396664b569491e41 296 Gene3D G3DSA:3.40.50.720 2 162 2.6E-41 T 14-10-2018 A4R43_41480 389d4abeec8dc2fd91d7e98423c312ff 1194 Pfam PF02514 CobN/Magnesium Chelatase 98 1176 0.0 T 14-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 A4R43_41480 389d4abeec8dc2fd91d7e98423c312ff 1194 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 24 1187 0.0 T 14-10-2018 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 A4R43_11005 e131f4ec9f43dcf052775f36d1844f68 265 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 3 214 5.0E-11 T 14-10-2018 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 SUPERFAMILY SSF48452 91 245 2.85E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 SUPERFAMILY SSF46894 4 81 1.98E-8 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 PRINTS PR00364 Disease resistance protein signature 280 295 3.7E-8 T 14-10-2018 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 PRINTS PR00364 Disease resistance protein signature 355 369 3.7E-8 T 14-10-2018 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 PRINTS PR00364 Disease resistance protein signature 440 454 3.7E-8 T 14-10-2018 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 Pfam PF00931 NB-ARC domain 280 506 4.7E-10 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 78 2.8E-4 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 SUPERFAMILY SSF52540 246 497 1.55E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 Gene3D G3DSA:1.10.10.10 1 92 4.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 Pfam PF03704 Bacterial transcriptional activator domain 96 236 2.8E-29 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 Gene3D G3DSA:3.40.50.300 249 401 6.2E-32 T 14-10-2018 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 SMART SM00862 16 89 8.8E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 Gene3D G3DSA:1.25.40.10 94 248 6.4E-38 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37490 38022d92fbcb0b6a1787db14f960c922 561 SMART SM01043 96 240 1.7E-35 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_04020 680f5b39880b33f726764a900d7bb49d 386 SUPERFAMILY SSF54826 21 123 1.11E-16 T 14-10-2018 A4R43_04020 680f5b39880b33f726764a900d7bb49d 386 SUPERFAMILY SSF51604 123 382 8.25E-48 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_04020 680f5b39880b33f726764a900d7bb49d 386 SMART SM00922 147 248 1.2E-14 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_04020 680f5b39880b33f726764a900d7bb49d 386 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 33 123 1.8E-8 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_04020 680f5b39880b33f726764a900d7bb49d 386 Pfam PF13378 Enolase C-terminal domain-like 153 373 1.5E-37 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_04020 680f5b39880b33f726764a900d7bb49d 386 Gene3D G3DSA:3.20.20.120 117 381 5.6E-58 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_04020 680f5b39880b33f726764a900d7bb49d 386 Gene3D G3DSA:3.30.390.10 1 115 9.2E-21 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_29390 26841920329000ef05047d779fe6d8e0 85 Gene3D G3DSA:1.10.1660.10 1 62 3.6E-12 T 14-10-2018 A4R43_29390 26841920329000ef05047d779fe6d8e0 85 SUPERFAMILY SSF46955 2 81 1.77E-9 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_29390 26841920329000ef05047d779fe6d8e0 85 Pfam PF13411 MerR HTH family regulatory protein 2 53 6.4E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_27110 64a2f47e65ddd5da18972a8db408d92d 439 Pfam PF00083 Sugar (and other) transporter 15 218 9.0E-19 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_27110 64a2f47e65ddd5da18972a8db408d92d 439 SUPERFAMILY SSF103473 10 429 3.01E-67 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_27110 64a2f47e65ddd5da18972a8db408d92d 439 Gene3D G3DSA:1.20.1250.20 12 433 5.1E-63 T 14-10-2018 A4R43_27110 64a2f47e65ddd5da18972a8db408d92d 439 Pfam PF07690 Major Facilitator Superfamily 258 428 2.2E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_26605 8587f9c3c3cb2436a580eca30e5e13a0 478 PIRSF PIRSF016636 1 478 8.8E-148 T 14-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB A4R43_26605 8587f9c3c3cb2436a580eca30e5e13a0 478 PIRSF PIRSF500217 1 478 4.9E-150 T 14-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 A4R43_26605 8587f9c3c3cb2436a580eca30e5e13a0 478 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 152 379 1.0E-32 T 14-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT A4R43_13130 2d78edd5b9097cb4413fadbd3158c7e0 545 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 63 339 6.6E-53 T 14-10-2018 IPR026588 Choice-of-anchor A domain A4R43_39450 c366e33d9385b1f2e42d81553ff6f6b9 346 Gene3D G3DSA:3.20.20.70 1 344 4.2E-105 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_39450 c366e33d9385b1f2e42d81553ff6f6b9 346 Pfam PF03060 Nitronate monooxygenase 7 334 6.6E-80 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_39450 c366e33d9385b1f2e42d81553ff6f6b9 346 SUPERFAMILY SSF51412 4 342 1.22E-53 T 14-10-2018 A4R43_30475 b8a1a0690d8d916711c923a603ed04d8 206 Pfam PF00583 Acetyltransferase (GNAT) family 34 139 1.0E-8 T 14-10-2018 IPR000182 GNAT domain A4R43_30475 b8a1a0690d8d916711c923a603ed04d8 206 Gene3D G3DSA:3.40.630.30 15 174 8.4E-10 T 14-10-2018 A4R43_30475 b8a1a0690d8d916711c923a603ed04d8 206 SUPERFAMILY SSF55729 32 164 8.72E-12 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 Gene3D G3DSA:1.10.1740.10 7 85 3.2E-11 T 14-10-2018 A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 Pfam PF04542 Sigma-70 region 2 16 81 2.5E-14 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 Gene3D G3DSA:3.10.450.50 175 293 9.9E-9 T 14-10-2018 A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 SUPERFAMILY SSF88659 106 167 2.24E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 167 2.0E-18 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 SUPERFAMILY SSF54427 179 289 8.11E-13 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 Gene3D G3DSA:1.10.10.10 94 170 1.6E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 Pfam PF08281 Sigma-70, region 4 114 165 3.2E-6 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_17630 101539ae9d2c8daf27748c2104c26621 303 SUPERFAMILY SSF88946 16 99 6.28E-18 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_31150 17b5e0249a32035e49ea3ff62b3b155b 401 SUPERFAMILY SSF52518 40 392 4.27E-98 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_31150 17b5e0249a32035e49ea3ff62b3b155b 401 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 42 389 4.3E-127 T 14-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4R43_31150 17b5e0249a32035e49ea3ff62b3b155b 401 Gene3D G3DSA:3.40.50.970 15 389 1.2E-115 T 14-10-2018 A4R43_31150 17b5e0249a32035e49ea3ff62b3b155b 401 Pfam PF00676 Dehydrogenase E1 component 75 350 1.0E-73 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A4R43_18870 411a6558e4e4c9f1f1b5da6897284d47 349 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 25 301 3.7E-63 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_18870 411a6558e4e4c9f1f1b5da6897284d47 349 Pfam PF02470 MlaD protein 42 117 8.0E-16 T 14-10-2018 IPR003399 Mce/MlaD A4R43_18870 411a6558e4e4c9f1f1b5da6897284d47 349 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 173 283 2.2E-7 T 14-10-2018 IPR024516 Mammalian cell entry, C-terminal A4R43_04960 71d517b64aae4ee5094455ed90728835 538 Gene3D G3DSA:3.40.50.10490 218 303 1.3E-9 T 14-10-2018 A4R43_04960 71d517b64aae4ee5094455ed90728835 538 Pfam PF00342 Phosphoglucose isomerase 84 254 1.0E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04960 71d517b64aae4ee5094455ed90728835 538 SUPERFAMILY SSF53697 14 379 1.17E-76 T 14-10-2018 A4R43_04960 71d517b64aae4ee5094455ed90728835 538 PRINTS PR00662 Glucose-6-phosphate isomerase signature 88 107 5.1E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04960 71d517b64aae4ee5094455ed90728835 538 PRINTS PR00662 Glucose-6-phosphate isomerase signature 266 287 5.1E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04960 71d517b64aae4ee5094455ed90728835 538 PRINTS PR00662 Glucose-6-phosphate isomerase signature 192 210 5.1E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04960 71d517b64aae4ee5094455ed90728835 538 Gene3D G3DSA:3.40.50.10490 330 384 1.0E-10 T 14-10-2018 A4R43_04960 71d517b64aae4ee5094455ed90728835 538 Gene3D G3DSA:3.40.50.10490 52 217 1.8E-36 T 14-10-2018 A4R43_40900 91e11a5e071d85cbe5502e1bb7ebb4a7 135 Pfam PF11774 Lsr2 1 112 3.8E-41 T 14-10-2018 IPR024412 Lsr2 A4R43_40900 91e11a5e071d85cbe5502e1bb7ebb4a7 135 Gene3D G3DSA:1.20.890.50 79 117 4.2E-15 T 14-10-2018 A4R43_40900 91e11a5e071d85cbe5502e1bb7ebb4a7 135 Gene3D G3DSA:3.30.60.230 1 60 1.1E-26 T 14-10-2018 A4R43_40900 91e11a5e071d85cbe5502e1bb7ebb4a7 135 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 112 4.0E-24 T 14-10-2018 IPR024412 Lsr2 A4R43_28305 6bd09cad5253677e0e414ce51a6547ac 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 243 8.4E-49 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_28305 6bd09cad5253677e0e414ce51a6547ac 315 Gene3D G3DSA:3.40.50.720 8 296 7.3E-84 T 14-10-2018 A4R43_28305 6bd09cad5253677e0e414ce51a6547ac 315 SUPERFAMILY SSF51735 2 310 1.48E-86 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28305 6bd09cad5253677e0e414ce51a6547ac 315 Gene3D G3DSA:3.90.25.10 175 306 7.3E-84 T 14-10-2018 A4R43_09620 16ea03122ac008e854dd901ff3dff0a2 221 Gene3D G3DSA:1.20.120.530 82 221 2.9E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_09620 16ea03122ac008e854dd901ff3dff0a2 221 SMART SM00345 19 77 1.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_09620 16ea03122ac008e854dd901ff3dff0a2 221 SUPERFAMILY SSF48008 84 219 8.37E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_09620 16ea03122ac008e854dd901ff3dff0a2 221 SUPERFAMILY SSF46785 12 104 2.5E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09620 16ea03122ac008e854dd901ff3dff0a2 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 1.3E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_09620 16ea03122ac008e854dd901ff3dff0a2 221 Gene3D G3DSA:1.10.10.10 11 77 3.4E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09620 16ea03122ac008e854dd901ff3dff0a2 221 SMART SM00895 87 212 4.1E-16 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_09620 16ea03122ac008e854dd901ff3dff0a2 221 Pfam PF07729 FCD domain 89 210 4.0E-21 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06085 afdc876014a1ca09946533d591c5907f 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.8E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06085 afdc876014a1ca09946533d591c5907f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06085 afdc876014a1ca09946533d591c5907f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06085 afdc876014a1ca09946533d591c5907f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06085 afdc876014a1ca09946533d591c5907f 303 Pfam PF03466 LysR substrate binding domain 89 295 2.9E-47 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_06085 afdc876014a1ca09946533d591c5907f 303 SUPERFAMILY SSF53850 88 299 3.88E-42 T 14-10-2018 A4R43_06085 afdc876014a1ca09946533d591c5907f 303 SUPERFAMILY SSF46785 1 111 1.96E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06085 afdc876014a1ca09946533d591c5907f 303 Gene3D G3DSA:3.40.190.290 91 298 1.7E-50 T 14-10-2018 A4R43_06085 afdc876014a1ca09946533d591c5907f 303 Gene3D G3DSA:1.10.10.10 1 83 1.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 SMART SM00490 249 330 1.2E-23 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 SMART SM00341 536 609 6.4E-10 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Gene3D G3DSA:1.10.150.80 540 608 1.5E-23 T 14-10-2018 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 SMART SM00956 410 516 5.9E-43 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Pfam PF00270 DEAD/DEAH box helicase 28 184 4.1E-19 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 13 606 2.9E-232 T 14-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 SUPERFAMILY SSF52540 206 459 9.21E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 14 465 8.9E-152 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Gene3D G3DSA:3.40.50.300 4 206 1.3E-76 T 14-10-2018 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 SMART SM00487 20 216 1.1E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Pfam PF00271 Helicase conserved C-terminal domain 223 329 4.9E-17 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 SUPERFAMILY SSF47819 535 608 8.94E-22 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Pfam PF09382 RQC domain 405 518 3.9E-33 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 SUPERFAMILY SSF52540 12 195 3.94E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Pfam PF16124 RecQ zinc-binding 342 403 1.0E-17 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Gene3D G3DSA:3.40.50.300 207 339 4.4E-40 T 14-10-2018 A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Gene3D G3DSA:1.10.10.10 340 528 3.5E-47 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41730 7f00b858bbc8828a02f8590d5e0ae7e1 609 Pfam PF00570 HRDC domain 541 606 3.9E-22 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PIRSF PIRSF001100 5 318 3.8E-97 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 Gene3D G3DSA:3.20.20.40 32 317 3.2E-95 T 14-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 96 109 3.0E-39 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 244 257 3.0E-39 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 54 73 3.0E-39 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 124 139 3.0E-39 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 180 193 3.0E-39 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 279 293 3.0E-39 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 210 220 3.0E-39 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 258 278 3.0E-39 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 Pfam PF01341 Glycosyl hydrolases family 6 52 297 8.8E-66 T 14-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 SUPERFAMILY SSF51989 33 315 6.41E-81 T 14-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 A4R43_36805 c3276d2f664197b376dc2fdfdeebca69 318 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 141 150 - T 14-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 A4R43_15520 f221ca03743a05ff8cb0ee7978e94070 361 SUPERFAMILY SSF52540 57 262 8.5E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15520 f221ca03743a05ff8cb0ee7978e94070 361 Gene3D G3DSA:3.40.50.300 59 235 5.1E-24 T 14-10-2018 A4R43_15520 f221ca03743a05ff8cb0ee7978e94070 361 Pfam PF07728 AAA domain (dynein-related subfamily) 79 217 6.5E-38 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A4R43_00675 e50fee0f624bde8f96829ae540c8f70f 271 Pfam PF01061 ABC-2 type transporter 21 234 3.4E-25 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_00675 e50fee0f624bde8f96829ae540c8f70f 271 PIRSF PIRSF006648 1 270 3.7E-73 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_17325 468ce6e081fe1453a850cfc2618bde91 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 234 5.6E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_17325 468ce6e081fe1453a850cfc2618bde91 256 SUPERFAMILY SSF161098 51 237 5.89E-25 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_17325 468ce6e081fe1453a850cfc2618bde91 256 Gene3D G3DSA:1.10.3720.10 49 243 9.1E-20 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 625 1.2E-217 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 242 268 1.3E-63 T 14-10-2018 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 108 128 1.3E-63 T 14-10-2018 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 155 176 1.3E-63 T 14-10-2018 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 1.3E-63 T 14-10-2018 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 80 105 1.3E-63 T 14-10-2018 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 417 436 1.3E-63 T 14-10-2018 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 310 322 1.3E-63 T 14-10-2018 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 56 80 8.7E-10 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 416 438 8.7E-10 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 260 282 8.7E-10 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 82 102 8.7E-10 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 119 4.9E-24 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33135 9ea72fb3ba4aa2a7bcfcb8a1c21c4ab5 631 Pfam PF00361 Proton-conducting membrane transporter 132 419 3.4E-83 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 SMART SM00354 27 97 7.6E-29 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 Gene3D G3DSA:3.40.50.2300 105 342 3.8E-75 T 14-10-2018 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 ProSitePatterns PS00356 LacI-type HTH domain signature. 30 48 - T 14-10-2018 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 Gene3D G3DSA:3.40.50.2300 185 346 3.8E-75 T 14-10-2018 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 SUPERFAMILY SSF47413 28 85 1.37E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 Gene3D G3DSA:1.10.260.40 21 85 2.8E-24 T 14-10-2018 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 Pfam PF13377 Periplasmic binding protein-like domain 194 351 2.7E-35 T 14-10-2018 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 Pfam PF00356 Bacterial regulatory proteins, lacI family 30 74 3.3E-20 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_10420 cd862380d4b4397f60457754b9c6f950 353 SUPERFAMILY SSF53822 84 345 8.25E-59 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_13565 5f4d700880cc41cc71fc022282ffab56 455 Gene3D G3DSA:2.160.20.80 211 442 5.3E-12 T 14-10-2018 A4R43_13565 5f4d700880cc41cc71fc022282ffab56 455 SUPERFAMILY SSF141571 215 373 9.03E-6 T 14-10-2018 A4R43_13565 5f4d700880cc41cc71fc022282ffab56 455 Pfam PF13576 Pentapeptide repeats (9 copies) 291 336 2.5E-8 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_13565 5f4d700880cc41cc71fc022282ffab56 455 Pfam PF13576 Pentapeptide repeats (9 copies) 345 392 1.6E-10 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_09245 f811ca4ebdff915061486cbb5338242d 440 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 7 414 2.6E-136 T 14-10-2018 IPR021228 Protein of unknown function DUF2791 A4R43_09245 f811ca4ebdff915061486cbb5338242d 440 SUPERFAMILY SSF52540 47 294 1.22E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_07795 502c51e487d15063cd0baf68f731a066 40 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 40 14.392 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_07795 502c51e487d15063cd0baf68f731a066 40 SUPERFAMILY SSF57840 1 40 2.09E-11 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_07795 502c51e487d15063cd0baf68f731a066 40 Pfam PF00444 Ribosomal protein L36 1 40 2.6E-16 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_22255 94df9a89832d5b068af8f3533e8766ab 333 Gene3D G3DSA:3.40.50.10440 11 184 4.3E-62 T 14-10-2018 A4R43_22255 94df9a89832d5b068af8f3533e8766ab 333 Gene3D G3DSA:3.30.1180.20 185 333 6.6E-50 T 14-10-2018 A4R43_22255 94df9a89832d5b068af8f3533e8766ab 333 SUPERFAMILY SSF82549 10 332 1.41E-118 T 14-10-2018 A4R43_22255 94df9a89832d5b068af8f3533e8766ab 333 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 7.8E-138 T 14-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 A4R43_22255 94df9a89832d5b068af8f3533e8766ab 333 Pfam PF02733 Dak1 domain 17 328 1.9E-124 T 14-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_35555 611006e2d118570f233bda2f7d9a1837 255 Gene3D G3DSA:3.40.50.450 43 255 5.0E-67 T 14-10-2018 A4R43_35555 611006e2d118570f233bda2f7d9a1837 255 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 72 245 1.5E-41 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG A4R43_35555 611006e2d118570f233bda2f7d9a1837 255 Pfam PF03641 Possible lysine decarboxylase 114 242 1.8E-32 T 14-10-2018 IPR031100 LOG family A4R43_35555 611006e2d118570f233bda2f7d9a1837 255 SUPERFAMILY SSF102405 42 244 1.48E-62 T 14-10-2018 A4R43_23750 0c66684f3f9eadf442212f35b30c3c24 425 Pfam PF04143 Sulphur transport 77 405 1.8E-62 T 14-10-2018 IPR007272 Sulphur transport domain A4R43_39105 31d6d60350e9890e8a9149265878a683 768 Pfam PF01568 Molydopterin dinucleotide binding domain 654 759 3.8E-11 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4R43_39105 31d6d60350e9890e8a9149265878a683 768 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 766 2.3E-297 T 14-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 A4R43_39105 31d6d60350e9890e8a9149265878a683 768 SUPERFAMILY SSF53706 60 645 2.09E-145 T 14-10-2018 A4R43_39105 31d6d60350e9890e8a9149265878a683 768 Gene3D G3DSA:2.40.40.20 646 767 5.2E-5 T 14-10-2018 A4R43_39105 31d6d60350e9890e8a9149265878a683 768 Gene3D G3DSA:3.40.228.10 201 423 1.9E-76 T 14-10-2018 A4R43_39105 31d6d60350e9890e8a9149265878a683 768 Pfam PF00384 Molybdopterin oxidoreductase 125 503 1.2E-28 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_39105 31d6d60350e9890e8a9149265878a683 768 SUPERFAMILY SSF50692 650 767 1.27E-17 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_39105 31d6d60350e9890e8a9149265878a683 768 PIRSF PIRSF000144 3 768 0.0 T 14-10-2018 A4R43_39105 31d6d60350e9890e8a9149265878a683 768 Gene3D G3DSA:3.40.50.740 133 528 1.9E-76 T 14-10-2018 A4R43_34410 b384959096a6c56a6613c409b3c65685 341 Pfam PF00069 Protein kinase domain 12 203 5.6E-24 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_34410 b384959096a6c56a6613c409b3c65685 341 Gene3D G3DSA:3.30.200.20 2 91 2.1E-18 T 14-10-2018 A4R43_34410 b384959096a6c56a6613c409b3c65685 341 SUPERFAMILY SSF56112 9 297 9.85E-49 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_34410 b384959096a6c56a6613c409b3c65685 341 Gene3D G3DSA:1.10.510.10 92 254 3.3E-27 T 14-10-2018 A4R43_00285 d23cd2d08ed1b822422c23375a0be257 453 Gene3D G3DSA:3.50.50.60 6 447 6.1E-98 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00285 d23cd2d08ed1b822422c23375a0be257 453 Pfam PF00890 FAD binding domain 6 425 2.3E-48 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_00285 d23cd2d08ed1b822422c23375a0be257 453 SUPERFAMILY SSF56425 250 393 2.79E-22 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_00285 d23cd2d08ed1b822422c23375a0be257 453 Gene3D G3DSA:3.90.700.10 243 389 6.1E-98 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_00285 d23cd2d08ed1b822422c23375a0be257 453 SUPERFAMILY SSF51905 6 452 2.1E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_14815 2360e56455ac79b6c415897fc0a1c2e2 631 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 412 618 2.4E-60 T 14-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal A4R43_14815 2360e56455ac79b6c415897fc0a1c2e2 631 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 345 371 7.6E-8 T 14-10-2018 IPR023908 xxxLxxG heptad repeat A4R43_14815 2360e56455ac79b6c415897fc0a1c2e2 631 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 205 230 1.2E-6 T 14-10-2018 IPR023908 xxxLxxG heptad repeat A4R43_14815 2360e56455ac79b6c415897fc0a1c2e2 631 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 189 210 1.5E-5 T 14-10-2018 IPR023908 xxxLxxG heptad repeat A4R43_14815 2360e56455ac79b6c415897fc0a1c2e2 631 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 171 1.1E-53 T 14-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal A4R43_14815 2360e56455ac79b6c415897fc0a1c2e2 631 Pfam PF12698 ABC-2 family transporter protein 26 612 3.3E-16 T 14-10-2018 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 144 174 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 PIRSF PIRSF001365 10 300 2.9E-78 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 12 296 55.716 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 49 66 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 SUPERFAMILY SSF51569 12 298 6.28E-90 T 14-10-2018 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 PRINTS PR00146 Dihydrodipicolinate synthase signature 82 100 3.6E-26 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 3.6E-26 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 PRINTS PR00146 Dihydrodipicolinate synthase signature 114 130 3.6E-26 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 3.6E-26 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 SMART SM01130 12 298 1.9E-114 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 Gene3D G3DSA:3.20.20.70 5 300 7.6E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 294 1.9E-79 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_41240 a1e2d341305b5bd602c9fe78cabd8350 337 Pfam PF00701 Dihydrodipicolinate synthetase family 13 296 1.2E-81 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_30055 e2d6c7f86c27f203def10e43023cc933 135 Pfam PF02036 SCP-2 sterol transfer family 21 112 7.5E-6 T 14-10-2018 IPR003033 SCP2 sterol-binding domain A4R43_30055 e2d6c7f86c27f203def10e43023cc933 135 SUPERFAMILY SSF55718 29 113 2.03E-12 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_30055 e2d6c7f86c27f203def10e43023cc933 135 Gene3D G3DSA:3.30.1050.10 3 116 1.1E-12 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 Gene3D G3DSA:3.50.50.60 14 310 1.5E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 SUPERFAMILY SSF51905 4 307 4.43E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 2.3E-15 T 14-10-2018 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.3E-15 T 14-10-2018 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 2.3E-15 T 14-10-2018 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 Gene3D G3DSA:3.50.50.60 133 249 1.5E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 14 36 8.8E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 118 126 8.8E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 206 222 8.8E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 71 81 8.8E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 8.8E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 Hamap MF_01685 Ferredoxin--NADP reductase. 12 331 38.906 T 14-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A4R43_30075 04e75a87ae76119dcf52f3e43c218201 357 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 291 1.7E-22 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_31810 68740061888952f86696c0a4494fbab0 235 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 9 141 3.1E-17 T 14-10-2018 IPR018763 Protein of unknown function DUF2334 A4R43_31810 68740061888952f86696c0a4494fbab0 235 SUPERFAMILY SSF88713 36 143 6.95E-10 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4R43_31810 68740061888952f86696c0a4494fbab0 235 Gene3D G3DSA:3.20.20.370 9 226 3.0E-10 T 14-10-2018 A4R43_08115 7bf34baf2208111d55f35d1c7b9b3701 287 Gene3D G3DSA:3.40.50.720 1 156 2.7E-33 T 14-10-2018 A4R43_08115 7bf34baf2208111d55f35d1c7b9b3701 287 PIRSF PIRSF000103 1 287 1.7E-29 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_08115 7bf34baf2208111d55f35d1c7b9b3701 287 Gene3D G3DSA:1.10.1040.10 158 286 5.4E-29 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_08115 7bf34baf2208111d55f35d1c7b9b3701 287 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 154 4.7E-16 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_08115 7bf34baf2208111d55f35d1c7b9b3701 287 SUPERFAMILY SSF51735 5 157 1.14E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 Gene3D G3DSA:3.30.499.10 270 432 1.5E-43 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 Gene3D G3DSA:3.30.499.20 4 267 1.9E-74 T 14-10-2018 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 Gene3D G3DSA:3.20.19.10 457 647 1.4E-43 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 Pfam PF00694 Aconitase C-terminal domain 524 580 3.0E-21 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 Pfam PF00330 Aconitase family (aconitate hydratase) 8 407 1.0E-89 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 SUPERFAMILY SSF52016 440 645 1.75E-52 T 14-10-2018 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 639 2.4E-228 T 14-10-2018 IPR006250 Aconitase, putative A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 PRINTS PR00415 Aconitase family signature 124 139 2.1E-20 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 PRINTS PR00415 Aconitase family signature 267 281 2.1E-20 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 PRINTS PR00415 Aconitase family signature 110 123 2.1E-20 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 PRINTS PR00415 Aconitase family signature 349 362 2.1E-20 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 PRINTS PR00415 Aconitase family signature 186 199 2.1E-20 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4R43_03280 030c014a7d613a3b1d10acf0e56174e9 652 SUPERFAMILY SSF53732 2 416 3.4E-129 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 Gene3D G3DSA:3.40.50.720 1 252 6.0E-80 T 14-10-2018 A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.7E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.7E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.7E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.7E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.7E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.7E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 SUPERFAMILY SSF51735 5 247 1.39E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 1.4E-63 T 14-10-2018 A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16645 00d3ec70e04d004d49ac1418643b6e51 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06740 b0262bab8feab44c12cd77871c2b470a 268 SUPERFAMILY SSF47090 51 112 9.02E-9 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_06740 b0262bab8feab44c12cd77871c2b470a 268 Gene3D G3DSA:1.10.101.10 40 115 1.1E-7 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_06740 b0262bab8feab44c12cd77871c2b470a 268 Pfam PF01471 Putative peptidoglycan binding domain 51 93 6.9E-5 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_31780 f2ad999a18d21d1bde487795c7cfcb6f 270 SMART SM00062 32 252 4.4E-49 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_31780 f2ad999a18d21d1bde487795c7cfcb6f 270 Gene3D G3DSA:3.40.190.10 33 249 3.3E-57 T 14-10-2018 A4R43_31780 f2ad999a18d21d1bde487795c7cfcb6f 270 Gene3D G3DSA:3.40.190.10 117 210 3.3E-57 T 14-10-2018 A4R43_31780 f2ad999a18d21d1bde487795c7cfcb6f 270 SUPERFAMILY SSF53850 8 251 9.79E-52 T 14-10-2018 A4R43_31780 f2ad999a18d21d1bde487795c7cfcb6f 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 250 6.2E-51 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_11685 5ae83712b684d2f8467426d701828ea0 291 Gene3D G3DSA:3.40.50.720 3 161 8.3E-40 T 14-10-2018 A4R43_11685 5ae83712b684d2f8467426d701828ea0 291 PIRSF PIRSF000103 1 291 7.8E-38 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_11685 5ae83712b684d2f8467426d701828ea0 291 Gene3D G3DSA:1.10.1040.10 162 290 3.3E-36 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_11685 5ae83712b684d2f8467426d701828ea0 291 SUPERFAMILY SSF51735 8 157 2.5E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11685 5ae83712b684d2f8467426d701828ea0 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 156 1.3E-22 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_35450 72f67a8a916a17e581ae193edbf4a3e2 288 SUPERFAMILY SSF53448 9 265 4.02E-40 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35450 72f67a8a916a17e581ae193edbf4a3e2 288 Gene3D G3DSA:3.90.550.10 3 245 3.5E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35450 72f67a8a916a17e581ae193edbf4a3e2 288 Pfam PF00535 Glycosyl transferase family 2 11 191 3.0E-16 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_12420 815e451eb41f7ec7b6484322b78a8123 667 SUPERFAMILY SSF48452 461 580 2.66E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12420 815e451eb41f7ec7b6484322b78a8123 667 SUPERFAMILY SSF48452 551 646 3.79E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12420 815e451eb41f7ec7b6484322b78a8123 667 Gene3D G3DSA:1.25.40.10 427 664 7.9E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12420 815e451eb41f7ec7b6484322b78a8123 667 SMART SM00382 37 245 4.1E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12420 815e451eb41f7ec7b6484322b78a8123 667 Gene3D G3DSA:3.40.50.300 2 155 1.2E-15 T 14-10-2018 A4R43_12420 815e451eb41f7ec7b6484322b78a8123 667 Pfam PF00931 NB-ARC domain 39 288 2.9E-7 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_12420 815e451eb41f7ec7b6484322b78a8123 667 SUPERFAMILY SSF52540 8 272 8.89E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21630 6cad3f65cbebeb74c3df1dce497dadbc 499 SUPERFAMILY SSF51556 88 412 3.4E-41 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_21630 6cad3f65cbebeb74c3df1dce497dadbc 499 Gene3D G3DSA:2.30.40.10 42 466 1.9E-84 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_21630 6cad3f65cbebeb74c3df1dce497dadbc 499 Gene3D G3DSA:3.20.20.140 90 471 1.9E-84 T 14-10-2018 A4R43_21630 6cad3f65cbebeb74c3df1dce497dadbc 499 Pfam PF07969 Amidohydrolase family 78 116 4.1E-7 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_21630 6cad3f65cbebeb74c3df1dce497dadbc 499 Pfam PF07969 Amidohydrolase family 228 459 8.8E-15 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_21630 6cad3f65cbebeb74c3df1dce497dadbc 499 SUPERFAMILY SSF51338 35 485 2.78E-22 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_19325 8740fc2044a8fe5e5510ff3a199d87a1 148 Gene3D G3DSA:3.40.930.10 2 142 4.4E-36 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A4R43_19325 8740fc2044a8fe5e5510ff3a199d87a1 148 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 140 6.1E-32 T 14-10-2018 IPR002178 PTS EIIA type-2 domain A4R43_19325 8740fc2044a8fe5e5510ff3a199d87a1 148 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 48 64 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain A4R43_19325 8740fc2044a8fe5e5510ff3a199d87a1 148 SUPERFAMILY SSF55804 3 140 1.57E-35 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 84 179 2.0E-12 T 14-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 SUPERFAMILY SSF49899 617 814 2.22E-36 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 659 810 4.5E-29 T 14-10-2018 A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 SUPERFAMILY SSF49785 38 209 1.56E-46 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 Gene3D G3DSA:3.20.20.80 318 596 8.9E-48 T 14-10-2018 A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 SMART SM00560 675 807 1.4E-23 T 14-10-2018 IPR006558 LamG-like jellyroll fold A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 Gene3D G3DSA:2.60.120.260 42 209 2.5E-42 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 Gene3D G3DSA:2.60.40.10 211 308 2.1E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 SUPERFAMILY SSF51445 304 591 2.16E-57 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 SUPERFAMILY SSF49303 213 308 4.6E-13 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 Pfam PF00703 Glycosyl hydrolases family 2 213 307 1.8E-10 T 14-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 A4R43_22570 04cf229663f5196d1c5b4ee10daf5938 816 Gene3D G3DSA:2.60.120.200 616 813 1.0E-36 T 14-10-2018 A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 Gene3D G3DSA:2.40.50.140 244 346 1.3E-14 T 14-10-2018 A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 SUPERFAMILY SSF50331 241 345 2.13E-16 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 Gene3D G3DSA:3.40.50.300 16 239 2.5E-62 T 14-10-2018 A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 SUPERFAMILY SSF52540 15 238 1.12E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 Pfam PF03459 TOBE domain 287 345 2.6E-11 T 14-10-2018 IPR005116 Transport-associated OB, type 1 A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 SMART SM00382 25 213 5.3E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 Gene3D G3DSA:2.40.50.100 273 343 1.3E-14 T 14-10-2018 A4R43_15460 1f92771c945967bb4cbfa23354d0cc72 350 Pfam PF00005 ABC transporter 19 163 1.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_34895 489b29a21e0aab96e3244ac3a3fb70ac 311 SUPERFAMILY SSF51430 9 291 4.71E-95 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_34895 489b29a21e0aab96e3244ac3a3fb70ac 311 Gene3D G3DSA:3.20.20.100 1 310 9.7E-116 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_34895 489b29a21e0aab96e3244ac3a3fb70ac 311 Pfam PF00248 Aldo/keto reductase family 12 290 2.3E-75 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_33920 eb8e1689e0422916cfa330c3177b5f4e 133 Gene3D G3DSA:3.30.420.100 18 133 1.0E-39 T 14-10-2018 A4R43_33920 eb8e1689e0422916cfa330c3177b5f4e 133 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 19 133 1.0E-46 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33920 eb8e1689e0422916cfa330c3177b5f4e 133 SUPERFAMILY SSF53137 20 131 1.74E-45 T 14-10-2018 A4R43_33920 eb8e1689e0422916cfa330c3177b5f4e 133 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 19 133 26.956 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33920 eb8e1689e0422916cfa330c3177b5f4e 133 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 22 133 2.8E-38 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_14400 ab3e984880fe9cfd75b86d96ffb51f84 318 SUPERFAMILY SSF53613 1 285 2.03E-65 T 14-10-2018 IPR029056 Ribokinase-like A4R43_14400 ab3e984880fe9cfd75b86d96ffb51f84 318 Gene3D G3DSA:3.40.1190.20 1 298 2.8E-77 T 14-10-2018 IPR029056 Ribokinase-like A4R43_14400 ab3e984880fe9cfd75b86d96ffb51f84 318 Pfam PF00294 pfkB family carbohydrate kinase 7 283 6.4E-47 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_19485 622971a8ae150af0f7980c8ef21458b8 201 Gene3D G3DSA:1.10.357.10 61 201 3.3E-37 T 14-10-2018 A4R43_19485 622971a8ae150af0f7980c8ef21458b8 201 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 187 8.6E-29 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_19485 622971a8ae150af0f7980c8ef21458b8 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 1.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19485 622971a8ae150af0f7980c8ef21458b8 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19485 622971a8ae150af0f7980c8ef21458b8 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19485 622971a8ae150af0f7980c8ef21458b8 201 Gene3D G3DSA:1.10.10.60 11 59 5.4E-22 T 14-10-2018 A4R43_19485 622971a8ae150af0f7980c8ef21458b8 201 SUPERFAMILY SSF48498 79 196 1.7E-25 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_19485 622971a8ae150af0f7980c8ef21458b8 201 SUPERFAMILY SSF46689 12 73 1.15E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 SUPERFAMILY SSF52540 268 448 1.5E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 Gene3D G3DSA:2.40.10.120 10 182 2.2E-10 T 14-10-2018 A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 Pfam PF13365 Trypsin-like peptidase domain 26 158 5.0E-13 T 14-10-2018 A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 SMART SM00567 E-Z type HEAT repeats 860 889 220.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 SMART SM00567 E-Z type HEAT repeats 893 922 280.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 SMART SM00567 E-Z type HEAT repeats 1200 1229 23.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 SMART SM00567 E-Z type HEAT repeats 827 856 460.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 Pfam PF05729 NACHT domain 269 428 2.4E-6 T 14-10-2018 IPR007111 NACHT nucleoside triphosphatase A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 SUPERFAMILY SSF48371 892 1086 4.75E-5 T 14-10-2018 IPR016024 Armadillo-type fold A4R43_12980 d19ffbb914c6dbae2305ea68e860e1b6 1247 SUPERFAMILY SSF50494 24 165 2.1E-17 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_13580 5682f08c960c37f69692d93b09ff7c55 233 Gene3D G3DSA:3.40.50.880 3 221 1.3E-66 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_13580 5682f08c960c37f69692d93b09ff7c55 233 Pfam PF01965 DJ-1/PfpI family 8 173 7.6E-26 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_13580 5682f08c960c37f69692d93b09ff7c55 233 SUPERFAMILY SSF52317 7 196 4.42E-47 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_39600 84daa0bcbe9a01541383509dd6a3654c 462 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 5 455 1.7E-180 T 14-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 A4R43_39600 84daa0bcbe9a01541383509dd6a3654c 462 Pfam PF01979 Amidohydrolase family 51 437 4.4E-27 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_39600 84daa0bcbe9a01541383509dd6a3654c 462 SUPERFAMILY SSF51338 3 65 4.97E-10 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_39600 84daa0bcbe9a01541383509dd6a3654c 462 Gene3D G3DSA:2.30.40.10 5 455 8.6E-178 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_39600 84daa0bcbe9a01541383509dd6a3654c 462 SUPERFAMILY SSF51556 55 383 4.67E-109 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_39600 84daa0bcbe9a01541383509dd6a3654c 462 Gene3D G3DSA:3.20.20.140 55 424 8.6E-178 T 14-10-2018 A4R43_39600 84daa0bcbe9a01541383509dd6a3654c 462 SUPERFAMILY SSF51338 358 456 1.57E-33 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_08785 ebf1e606de32b7159955c9e67aa0f7a9 380 Gene3D G3DSA:3.40.50.2000 196 360 6.6E-98 T 14-10-2018 A4R43_08785 ebf1e606de32b7159955c9e67aa0f7a9 380 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 209 377 1.7E-41 T 14-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 A4R43_08785 ebf1e606de32b7159955c9e67aa0f7a9 380 SUPERFAMILY SSF53756 2 378 1.99E-78 T 14-10-2018 A4R43_08785 ebf1e606de32b7159955c9e67aa0f7a9 380 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 214 356 1.3E-18 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_08785 ebf1e606de32b7159955c9e67aa0f7a9 380 Gene3D G3DSA:3.40.50.2000 2 365 6.6E-98 T 14-10-2018 A4R43_06110 2432f9a9db952138642af150288091be 310 SUPERFAMILY SSF53850 90 291 4.68E-42 T 14-10-2018 A4R43_06110 2432f9a9db952138642af150288091be 310 Gene3D G3DSA:3.40.190.290 90 293 8.1E-50 T 14-10-2018 A4R43_06110 2432f9a9db952138642af150288091be 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06110 2432f9a9db952138642af150288091be 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06110 2432f9a9db952138642af150288091be 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06110 2432f9a9db952138642af150288091be 310 Gene3D G3DSA:1.10.10.10 1 85 8.4E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06110 2432f9a9db952138642af150288091be 310 Pfam PF03466 LysR substrate binding domain 89 287 3.5E-46 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_06110 2432f9a9db952138642af150288091be 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.8E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06110 2432f9a9db952138642af150288091be 310 SUPERFAMILY SSF46785 3 111 3.73E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01490 b1c5c2af363659f6104a31da7a01953a 211 SUPERFAMILY SSF53474 10 209 1.82E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01490 b1c5c2af363659f6104a31da7a01953a 211 Pfam PF01738 Dienelactone hydrolase family 18 192 2.3E-8 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 A4R43_01490 b1c5c2af363659f6104a31da7a01953a 211 Gene3D G3DSA:3.40.50.1820 2 210 3.9E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_17595 da05e0672de26c9bc0196a49be4e9d3c 240 PIRSF PIRSF006755 1 202 2.4E-32 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A4R43_17595 da05e0672de26c9bc0196a49be4e9d3c 240 Pfam PF13500 AAA domain 4 199 4.2E-33 T 14-10-2018 A4R43_17595 da05e0672de26c9bc0196a49be4e9d3c 240 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 217 23.064 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A4R43_17595 da05e0672de26c9bc0196a49be4e9d3c 240 Gene3D G3DSA:3.40.50.300 2 222 5.5E-55 T 14-10-2018 A4R43_17595 da05e0672de26c9bc0196a49be4e9d3c 240 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 169 1.1E-30 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A4R43_17595 da05e0672de26c9bc0196a49be4e9d3c 240 SUPERFAMILY SSF52540 3 199 2.19E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28865 24b0ab7b885cc07a4ccc4439f0faed53 325 SUPERFAMILY SSF53850 51 321 3.62E-63 T 14-10-2018 A4R43_28865 24b0ab7b885cc07a4ccc4439f0faed53 325 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 51 316 1.4E-58 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 A4R43_28865 24b0ab7b885cc07a4ccc4439f0faed53 325 Gene3D G3DSA:3.40.190.120 153 260 6.7E-96 T 14-10-2018 A4R43_28865 24b0ab7b885cc07a4ccc4439f0faed53 325 Gene3D G3DSA:3.40.190.10 53 321 6.7E-96 T 14-10-2018 A4R43_36890 f872118d814201cf447c247cb176ef50 563 SUPERFAMILY SSF82549 12 327 1.12E-102 T 14-10-2018 A4R43_36890 f872118d814201cf447c247cb176ef50 563 SMART SM01120 382 553 4.9E-49 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_36890 f872118d814201cf447c247cb176ef50 563 SUPERFAMILY SSF101473 356 553 2.62E-44 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_36890 f872118d814201cf447c247cb176ef50 563 Pfam PF02733 Dak1 domain 17 324 1.2E-106 T 14-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_36890 f872118d814201cf447c247cb176ef50 563 Pfam PF02734 DAK2 domain 383 551 1.3E-40 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_36890 f872118d814201cf447c247cb176ef50 563 Gene3D G3DSA:3.40.50.10440 12 182 4.8E-53 T 14-10-2018 A4R43_36890 f872118d814201cf447c247cb176ef50 563 Gene3D G3DSA:3.30.1180.20 184 329 2.1E-43 T 14-10-2018 A4R43_36890 f872118d814201cf447c247cb176ef50 563 Gene3D G3DSA:1.25.40.340 353 556 9.0E-48 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4R43_23815 e87d6bd77f814980e1c3f20e230fa3ba 192 Gene3D G3DSA:2.60.40.2880 105 192 3.7E-14 T 14-10-2018 IPR038468 Transport accessory protein MmpS, soluble domain superfamily A4R43_23815 e87d6bd77f814980e1c3f20e230fa3ba 192 Pfam PF05423 Mycobacterium membrane protein 104 189 9.3E-7 T 14-10-2018 IPR008693 Transport accessory protein MmpS A4R43_32850 cfa596503bcaaec5ee9610cf1e193fa0 268 SUPERFAMILY SSF53474 3 264 2.79E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_32850 cfa596503bcaaec5ee9610cf1e193fa0 268 Pfam PF12697 Alpha/beta hydrolase family 36 258 2.1E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_32850 cfa596503bcaaec5ee9610cf1e193fa0 268 Gene3D G3DSA:3.40.50.1820 1 264 1.2E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 SUPERFAMILY SSF52833 52 167 1.88E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 ProSitePatterns PS00194 Thioredoxin family active site. 82 100 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 Pfam PF00085 Thioredoxin 60 162 8.9E-25 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 Gene3D G3DSA:1.25.40.10 242 322 3.5E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 Pfam PF14561 Tetratricopeptide repeat 245 322 9.1E-18 T 14-10-2018 A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 PRINTS PR00421 Thioredoxin family signature 129 140 2.7E-5 T 14-10-2018 A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 PRINTS PR00421 Thioredoxin family signature 89 98 2.7E-5 T 14-10-2018 A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 PRINTS PR00421 Thioredoxin family signature 81 89 2.7E-5 T 14-10-2018 A4R43_20475 e5f767e01e51b62aa6fad71fb236b884 322 Gene3D G3DSA:3.40.30.10 56 167 1.9E-29 T 14-10-2018 A4R43_41505 08440b6322f850be7d41dfcaeb13f6ee 207 SUPERFAMILY SSF63965 2 204 5.89E-72 T 14-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 A4R43_41505 08440b6322f850be7d41dfcaeb13f6ee 207 Gene3D G3DSA:3.40.50.10230 1 207 9.3E-81 T 14-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 A4R43_41505 08440b6322f850be7d41dfcaeb13f6ee 207 Pfam PF02570 Precorrin-8X methylmutase 10 204 4.3E-71 T 14-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 Gene3D G3DSA:3.40.50.720 1 237 1.3E-57 T 14-10-2018 A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 7.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 7.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 7.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 7.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 7.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 6.3E-39 T 14-10-2018 A4R43_40055 de9c1b749651c25c7fdeb7121fe773b6 240 SUPERFAMILY SSF51735 3 236 1.21E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 Pfam PF00931 NB-ARC domain 16 225 1.9E-11 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SUPERFAMILY SSF48452 615 820 9.39E-40 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 PRINTS PR00364 Disease resistance protein signature 35 50 1.1E-9 T 14-10-2018 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 PRINTS PR00364 Disease resistance protein signature 120 134 1.1E-9 T 14-10-2018 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 PRINTS PR00364 Disease resistance protein signature 210 224 1.1E-9 T 14-10-2018 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 Gene3D G3DSA:3.40.50.300 2 164 7.3E-26 T 14-10-2018 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SUPERFAMILY SSF52540 11 267 3.0E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 Gene3D G3DSA:1.25.40.10 401 663 5.9E-62 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 Pfam PF13424 Tetratricopeptide repeat 498 569 2.9E-13 T 14-10-2018 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 Pfam PF13424 Tetratricopeptide repeat 738 808 3.4E-12 T 14-10-2018 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 Pfam PF13424 Tetratricopeptide repeat 659 729 5.9E-12 T 14-10-2018 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 Pfam PF13424 Tetratricopeptide repeat 578 649 5.1E-13 T 14-10-2018 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 577 610 5.1E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 457 490 230.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 657 690 0.0013 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 737 770 0.0012 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 537 570 0.055 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 777 810 2.7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 617 650 0.0015 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 697 730 0.12 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SMART SM00028 497 530 5.4E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 SUPERFAMILY SSF48452 455 623 6.7E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_15055 6bca7d99d5e21710639e0f76ee039644 827 Gene3D G3DSA:1.25.40.10 664 824 7.1E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_06315 1c84902885044f5acf924360a447637b 182 Gene3D G3DSA:1.20.1440.130 5 176 1.2E-19 T 14-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 A4R43_06315 1c84902885044f5acf924360a447637b 182 Pfam PF07884 Vitamin K epoxide reductase family 12 143 6.9E-32 T 14-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 A4R43_06315 1c84902885044f5acf924360a447637b 182 SMART SM00756 6 147 7.4E-56 T 14-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 A4R43_28750 d597a08a99191ed25feba991360ae9c8 506 SUPERFAMILY SSF53335 41 235 7.4E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_28750 d597a08a99191ed25feba991360ae9c8 506 Gene3D G3DSA:3.40.50.150 29 232 9.5E-22 T 14-10-2018 A4R43_28750 d597a08a99191ed25feba991360ae9c8 506 Pfam PF13489 Methyltransferase domain 45 203 1.6E-12 T 14-10-2018 A4R43_30865 d37770ea8f80bb3d8a621dac62cff410 246 Pfam PF01061 ABC-2 type transporter 9 209 8.4E-28 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_30865 d37770ea8f80bb3d8a621dac62cff410 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 188 207 1.6E-7 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_30865 d37770ea8f80bb3d8a621dac62cff410 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 96 121 1.6E-7 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_30865 d37770ea8f80bb3d8a621dac62cff410 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 168 187 1.6E-7 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_30865 d37770ea8f80bb3d8a621dac62cff410 246 PIRSF PIRSF006648 1 246 2.4E-48 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_30105 c93edae3870aa670cbcc3dcae4e72c8c 451 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 305 326 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 A4R43_30105 c93edae3870aa670cbcc3dcae4e72c8c 451 Pfam PF00639 PPIC-type PPIASE domain 287 363 1.3E-15 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 A4R43_30105 c93edae3870aa670cbcc3dcae4e72c8c 451 SUPERFAMILY SSF109998 126 306 6.28E-22 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily A4R43_30105 c93edae3870aa670cbcc3dcae4e72c8c 451 Gene3D G3DSA:3.10.50.40 277 368 5.5E-30 T 14-10-2018 A4R43_30105 c93edae3870aa670cbcc3dcae4e72c8c 451 Pfam PF13624 SurA N-terminal domain 105 246 6.0E-7 T 14-10-2018 A4R43_30105 c93edae3870aa670cbcc3dcae4e72c8c 451 Gene3D G3DSA:1.10.4030.30 132 382 5.5E-30 T 14-10-2018 A4R43_30105 c93edae3870aa670cbcc3dcae4e72c8c 451 SUPERFAMILY SSF54534 275 369 7.46E-19 T 14-10-2018 A4R43_39670 b2e32f882b5a292430467b21fc34bd2a 112 SUPERFAMILY SSF53927 8 88 3.72E-9 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_39670 b2e32f882b5a292430467b21fc34bd2a 112 Gene3D G3DSA:3.40.140.10 5 111 3.1E-6 T 14-10-2018 A4R43_12435 f9c5cf5c8176e10b765949f1469d0261 267 SUPERFAMILY SSF81301 5 118 7.36E-19 T 14-10-2018 A4R43_12435 f9c5cf5c8176e10b765949f1469d0261 267 SUPERFAMILY SSF81631 131 252 2.43E-25 T 14-10-2018 A4R43_12435 f9c5cf5c8176e10b765949f1469d0261 267 Gene3D G3DSA:1.20.120.330 130 265 7.0E-11 T 14-10-2018 A4R43_12435 f9c5cf5c8176e10b765949f1469d0261 267 Gene3D G3DSA:3.30.460.10 8 129 1.2E-14 T 14-10-2018 A4R43_12435 f9c5cf5c8176e10b765949f1469d0261 267 Pfam PF04439 Streptomycin adenylyltransferase 7 250 2.7E-33 T 14-10-2018 IPR007530 Aminoglycoside 6-adenylyltransferase A4R43_19145 84e81e6ceef13d88149d29cbc553a859 423 Gene3D G3DSA:3.90.1150.10 11 394 2.5E-174 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_19145 84e81e6ceef13d88149d29cbc553a859 423 PIRSF PIRSF000412 1 418 4.7E-156 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_19145 84e81e6ceef13d88149d29cbc553a859 423 Pfam PF00464 Serine hydroxymethyltransferase 8 389 5.5E-161 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_19145 84e81e6ceef13d88149d29cbc553a859 423 Gene3D G3DSA:3.40.640.10 37 287 2.5E-174 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_19145 84e81e6ceef13d88149d29cbc553a859 423 SUPERFAMILY SSF53383 4 420 4.08E-168 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_19145 84e81e6ceef13d88149d29cbc553a859 423 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_19145 84e81e6ceef13d88149d29cbc553a859 423 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 420 50.124 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_12110 df4744b24c046622201246c1b42c2ee9 299 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 8 296 6.3E-111 T 14-10-2018 IPR017685 HTH-type transcriptional regulator ArgP A4R43_12110 df4744b24c046622201246c1b42c2ee9 299 Gene3D G3DSA:1.10.10.10 1 86 4.2E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12110 df4744b24c046622201246c1b42c2ee9 299 SUPERFAMILY SSF46785 6 114 1.36E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_12110 df4744b24c046622201246c1b42c2ee9 299 Gene3D G3DSA:3.40.190.290 91 298 5.3E-79 T 14-10-2018 A4R43_12110 df4744b24c046622201246c1b42c2ee9 299 Pfam PF03466 LysR substrate binding domain 93 292 7.4E-17 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_12110 df4744b24c046622201246c1b42c2ee9 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.1E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_12110 df4744b24c046622201246c1b42c2ee9 299 SUPERFAMILY SSF53850 95 294 2.35E-23 T 14-10-2018 A4R43_08860 13ede27301003b4abdc02cefce65a204 278 SUPERFAMILY SSF51735 2 247 1.79E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_08860 13ede27301003b4abdc02cefce65a204 278 Gene3D G3DSA:3.40.50.720 3 278 5.3E-66 T 14-10-2018 A4R43_08860 13ede27301003b4abdc02cefce65a204 278 Pfam PF13460 NAD(P)H-binding 7 177 1.1E-23 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_00225 7d8f47f150a88c79fb1c3c7750ac1dad 378 Pfam PF02720 Domain of unknown function (DUF222) 9 297 8.0E-11 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_10515 434d4676327f157a107e8b66434cf630 396 Gene3D G3DSA:3.40.640.10 19 265 2.9E-127 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_10515 434d4676327f157a107e8b66434cf630 396 PIRSF PIRSF000524 1 391 3.8E-130 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A4R43_10515 434d4676327f157a107e8b66434cf630 396 Pfam PF00266 Aminotransferase class-V 9 322 4.2E-38 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_10515 434d4676327f157a107e8b66434cf630 396 Gene3D G3DSA:3.90.1150.10 14 376 2.9E-127 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_10515 434d4676327f157a107e8b66434cf630 396 SUPERFAMILY SSF53383 6 368 1.62E-107 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_40620 74ea7ab803fb86c24181683cfeba0ac5 359 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 67 1.4E-6 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_40620 74ea7ab803fb86c24181683cfeba0ac5 359 Gene3D G3DSA:3.40.50.720 2 113 1.1E-15 T 14-10-2018 A4R43_40620 74ea7ab803fb86c24181683cfeba0ac5 359 SUPERFAMILY SSF51735 2 141 5.76E-11 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 46 476 1.4E-139 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01181 Diaminopimelate decarboxylase signature 201 210 2.8E-26 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01181 Diaminopimelate decarboxylase signature 355 373 2.8E-26 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01181 Diaminopimelate decarboxylase signature 444 466 2.8E-26 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01181 Diaminopimelate decarboxylase signature 112 129 2.8E-26 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 SUPERFAMILY SSF51419 64 333 6.11E-73 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 339 434 7.0E-14 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 53 477 38.594 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 73 331 9.2E-63 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 268 285 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 94 112 1.4E-16 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 229 242 1.4E-16 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 322 341 1.4E-16 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 114 126 1.4E-16 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 434 447 1.4E-16 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 Gene3D G3DSA:2.40.37.10 51 473 1.7E-162 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 SUPERFAMILY SSF50621 306 477 3.98E-46 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 94 112 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A4R43_22460 4681964c143540e2b94e8eb9f5bb7ab0 478 Gene3D G3DSA:3.20.20.10 72 332 1.7E-162 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_31265 d45cfac860f30a9a177869aa191e6a2a 110 SUPERFAMILY SSF103481 10 108 4.97E-12 T 14-10-2018 A4R43_31265 d45cfac860f30a9a177869aa191e6a2a 110 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 109 4.0E-44 T 14-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 A4R43_31265 d45cfac860f30a9a177869aa191e6a2a 110 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 21.551 T 14-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 A4R43_23415 39f08ce146b67c571e2bb98cf5780128 349 Pfam PF13343 Bacterial extracellular solute-binding protein 84 322 9.3E-29 T 14-10-2018 A4R43_23415 39f08ce146b67c571e2bb98cf5780128 349 SUPERFAMILY SSF53850 35 344 8.4E-52 T 14-10-2018 A4R43_23415 39f08ce146b67c571e2bb98cf5780128 349 Gene3D G3DSA:3.40.190.10 38 318 1.3E-101 T 14-10-2018 A4R43_23415 39f08ce146b67c571e2bb98cf5780128 349 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 34 343 2.6E-64 T 14-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 A4R43_23415 39f08ce146b67c571e2bb98cf5780128 349 Gene3D G3DSA:3.40.190.10 135 344 1.3E-101 T 14-10-2018 A4R43_09570 bfeada8c44a1680e013dba19f261615d 606 SUPERFAMILY SSF52279 439 606 3.14E-18 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_09570 bfeada8c44a1680e013dba19f261615d 606 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 56 399 1.3E-101 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_09570 bfeada8c44a1680e013dba19f261615d 606 SUPERFAMILY SSF51445 45 435 1.47E-103 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_09570 bfeada8c44a1680e013dba19f261615d 606 Gene3D G3DSA:3.20.20.300 42 421 3.2E-126 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_09570 bfeada8c44a1680e013dba19f261615d 606 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 438 605 1.9E-15 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_09570 bfeada8c44a1680e013dba19f261615d 606 Gene3D G3DSA:3.40.50.1700 422 606 1.1E-35 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_21895 61670de2446e62485d74109448fedd04 837 Pfam PF02687 FtsX-like permease family 740 827 5.3E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_21895 61670de2446e62485d74109448fedd04 837 Pfam PF02687 FtsX-like permease family 286 380 6.7E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_21895 61670de2446e62485d74109448fedd04 837 Pfam PF12704 MacB-like periplasmic core domain 485 683 5.8E-8 T 14-10-2018 IPR025857 MacB-like periplasmic core domain A4R43_35755 869eda3774129a63cdf23462f1a0e422 219 Gene3D G3DSA:3.60.21.10 37 206 5.5E-11 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_35755 869eda3774129a63cdf23462f1a0e422 219 Pfam PF00149 Calcineurin-like phosphoesterase 30 188 3.3E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_35755 869eda3774129a63cdf23462f1a0e422 219 SUPERFAMILY SSF56300 11 206 3.64E-28 T 14-10-2018 A4R43_37815 f7aa20a9ad307ef441c71d9229959229 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 8.3E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_37815 f7aa20a9ad307ef441c71d9229959229 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.4E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_37815 f7aa20a9ad307ef441c71d9229959229 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.4E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_37815 f7aa20a9ad307ef441c71d9229959229 196 Gene3D G3DSA:1.10.357.10 4 193 2.0E-35 T 14-10-2018 A4R43_37815 f7aa20a9ad307ef441c71d9229959229 196 SUPERFAMILY SSF46689 6 78 5.49E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22310 c0868d03e020572e0f9efc6ca792315f 658 Pfam PF01642 Methylmalonyl-CoA mutase 1 487 7.5E-128 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_22310 c0868d03e020572e0f9efc6ca792315f 658 Gene3D G3DSA:3.20.20.240 1 505 4.7E-164 T 14-10-2018 A4R43_22310 c0868d03e020572e0f9efc6ca792315f 658 SUPERFAMILY SSF51703 1 489 8.24E-153 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_22310 c0868d03e020572e0f9efc6ca792315f 658 SUPERFAMILY SSF52242 503 652 5.1E-49 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_22310 c0868d03e020572e0f9efc6ca792315f 658 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 525 653 6.7E-40 T 14-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_22310 c0868d03e020572e0f9efc6ca792315f 658 Pfam PF02310 B12 binding domain 527 632 3.5E-18 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_22310 c0868d03e020572e0f9efc6ca792315f 658 Gene3D G3DSA:3.40.50.280 507 657 2.5E-49 T 14-10-2018 A4R43_22310 c0868d03e020572e0f9efc6ca792315f 658 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 1 493 9.7E-135 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_00400 b04d41e18368bf863dde21325bf942cb 253 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_00400 b04d41e18368bf863dde21325bf942cb 253 SMART SM00382 36 222 2.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_00400 b04d41e18368bf863dde21325bf942cb 253 Pfam PF00005 ABC transporter 27 173 6.2E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_00400 b04d41e18368bf863dde21325bf942cb 253 SUPERFAMILY SSF52540 8 226 1.39E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_00400 b04d41e18368bf863dde21325bf942cb 253 Gene3D G3DSA:3.40.50.300 7 250 6.4E-70 T 14-10-2018 A4R43_18910 aaef2fc762f49965791b841c81652c2d 590 Gene3D G3DSA:1.20.1730.10 6 228 1.4E-26 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_18910 aaef2fc762f49965791b841c81652c2d 590 Gene3D G3DSA:1.20.1730.10 260 544 3.2E-16 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_18910 aaef2fc762f49965791b841c81652c2d 590 Pfam PF00474 Sodium:solute symporter family 31 199 2.1E-24 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_18910 aaef2fc762f49965791b841c81652c2d 590 Pfam PF00474 Sodium:solute symporter family 300 488 4.9E-14 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_37325 e8cecbee2f98000b0480cf883a01138f 510 SUPERFAMILY SSF52096 239 510 4.68E-87 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_37325 e8cecbee2f98000b0480cf883a01138f 510 Gene3D G3DSA:3.90.226.10 259 510 5.1E-93 T 14-10-2018 A4R43_37325 e8cecbee2f98000b0480cf883a01138f 510 Pfam PF01039 Carboxyl transferase domain 23 507 4.1E-178 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_37325 e8cecbee2f98000b0480cf883a01138f 510 Gene3D G3DSA:3.90.226.10 2 252 1.2E-80 T 14-10-2018 A4R43_37325 e8cecbee2f98000b0480cf883a01138f 510 SUPERFAMILY SSF52096 21 250 5.73E-69 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_08480 cab683ed79fcc007f803a9c18323330a 222 Pfam PF12697 Alpha/beta hydrolase family 4 208 2.6E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_08480 cab683ed79fcc007f803a9c18323330a 222 SUPERFAMILY SSF53474 3 214 2.77E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08480 cab683ed79fcc007f803a9c18323330a 222 Gene3D G3DSA:3.40.50.1820 2 214 9.6E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20435 7a05fcf5479213cc1d13dc5e6c020ffd 131 SMART SM00450 18 121 1.1E-16 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_20435 7a05fcf5479213cc1d13dc5e6c020ffd 131 Gene3D G3DSA:3.40.250.10 2 124 7.2E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_20435 7a05fcf5479213cc1d13dc5e6c020ffd 131 Pfam PF00581 Rhodanese-like domain 23 117 1.3E-10 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_20435 7a05fcf5479213cc1d13dc5e6c020ffd 131 SUPERFAMILY SSF52821 8 125 8.51E-23 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_40535 6129e08f044127e7cada0d1d17fcf6d4 649 SUPERFAMILY SSF74650 4 198 7.85E-26 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A4R43_40535 6129e08f044127e7cada0d1d17fcf6d4 649 Gene3D G3DSA:2.60.40.1760 1 212 1.7E-42 T 14-10-2018 A4R43_40535 6129e08f044127e7cada0d1d17fcf6d4 649 SUPERFAMILY SSF51011 563 640 3.09E-22 T 14-10-2018 A4R43_40535 6129e08f044127e7cada0d1d17fcf6d4 649 Pfam PF13802 Galactose mutarotase-like 121 174 1.0E-6 T 14-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain A4R43_40535 6129e08f044127e7cada0d1d17fcf6d4 649 Gene3D G3DSA:2.60.40.1180 565 640 3.4E-26 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta A4R43_40535 6129e08f044127e7cada0d1d17fcf6d4 649 Gene3D G3DSA:3.20.20.80 213 562 7.1E-103 T 14-10-2018 A4R43_40535 6129e08f044127e7cada0d1d17fcf6d4 649 Pfam PF01055 Glycosyl hydrolases family 31 196 643 1.1E-113 T 14-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 A4R43_40535 6129e08f044127e7cada0d1d17fcf6d4 649 SUPERFAMILY SSF51445 203 561 8.43E-61 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_09640 0478a90782eec4c729f54b7e54851663 91 Pfam PF04267 Sarcosine oxidase, delta subunit family 3 83 2.4E-36 T 14-10-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 A4R43_09640 0478a90782eec4c729f54b7e54851663 91 Gene3D G3DSA:3.30.2270.10 1 91 3.3E-35 T 14-10-2018 IPR038561 Sarcosine oxidase subunit delta superfamily KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 A4R43_09640 0478a90782eec4c729f54b7e54851663 91 TIGRFAM TIGR01374 soxD: sarcosine oxidase, delta subunit family 3 82 1.7E-35 T 14-10-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 Hamap MF_00008 Thymidylate synthase [thyA]. 3 265 38.398 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 Pfam PF00303 Thymidylate synthase 5 265 3.8E-120 T 14-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 PRINTS PR00108 Thymidylate synthase family signature 44 65 7.6E-48 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 PRINTS PR00108 Thymidylate synthase family signature 143 158 7.6E-48 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 PRINTS PR00108 Thymidylate synthase family signature 161 187 7.6E-48 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 PRINTS PR00108 Thymidylate synthase family signature 117 136 7.6E-48 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 PRINTS PR00108 Thymidylate synthase family signature 199 216 7.6E-48 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 SUPERFAMILY SSF55831 3 265 1.83E-122 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 5 86 1.1E-38 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 88 265 5.4E-89 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 Gene3D G3DSA:3.30.572.10 3 265 1.4E-124 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_12935 edfcf58d9babdfb257cdbef039ffb1ad 265 ProSitePatterns PS00091 Thymidylate synthase active site. 128 156 - T 14-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A4R43_35675 f849238712c505607697ae083123c132 381 Hamap MF_02040 Iron-sulfur cluster carrier protein. 97 363 33.626 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A4R43_35675 f849238712c505607697ae083123c132 381 Gene3D G3DSA:3.30.300.130 6 101 2.3E-23 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4R43_35675 f849238712c505607697ae083123c132 381 SUPERFAMILY SSF117916 9 99 2.58E-25 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4R43_35675 f849238712c505607697ae083123c132 381 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 117 362 1.9E-88 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A4R43_35675 f849238712c505607697ae083123c132 381 SUPERFAMILY SSF52540 117 362 1.93E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35675 f849238712c505607697ae083123c132 381 Pfam PF01883 Iron-sulfur cluster assembly protein 11 83 4.7E-20 T 14-10-2018 IPR002744 MIP18 family-like A4R43_35675 f849238712c505607697ae083123c132 381 Gene3D G3DSA:3.40.50.300 112 361 4.6E-69 T 14-10-2018 A4R43_01380 94399541cdbab7bf1e950e1b66a13fa0 410 Gene3D G3DSA:1.20.1250.20 214 391 7.9E-17 T 14-10-2018 A4R43_01380 94399541cdbab7bf1e950e1b66a13fa0 410 Gene3D G3DSA:1.20.1250.20 14 203 4.2E-19 T 14-10-2018 A4R43_01380 94399541cdbab7bf1e950e1b66a13fa0 410 Pfam PF07690 Major Facilitator Superfamily 41 356 3.2E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_01380 94399541cdbab7bf1e950e1b66a13fa0 410 SUPERFAMILY SSF103473 16 393 2.49E-45 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 200 3.2E-4 T 14-10-2018 A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 Gene3D G3DSA:3.40.50.720 3 298 5.3E-84 T 14-10-2018 A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.7E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 2.7E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 2.7E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.7E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 2.7E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 Pfam PF00106 short chain dehydrogenase 7 211 3.3E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 SUPERFAMILY SSF51735 3 256 4.85E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_15940 91adf4bcd5afbcabced0a89f9ea65473 298 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 SUPERFAMILY SSF50331 238 361 3.97E-28 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 Pfam PF00005 ABC transporter 22 163 4.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 Gene3D G3DSA:2.40.50.140 284 345 2.7E-31 T 14-10-2018 A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 Gene3D G3DSA:2.40.50.940 224 354 2.7E-31 T 14-10-2018 A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 Gene3D G3DSA:3.40.50.300 4 223 5.2E-62 T 14-10-2018 A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 SUPERFAMILY SSF52540 5 243 3.6E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 Pfam PF08402 TOBE domain 277 353 2.4E-7 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A4R43_34200 c62d04354f3db6a110266a6df5af4e45 362 SMART SM00382 30 213 7.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 250 618 6.4E-165 T 14-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 24 246 4.9E-98 T 14-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 Gene3D G3DSA:2.170.8.10 60 409 2.8E-264 T 14-10-2018 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 SUPERFAMILY SSF53795 250 618 3.2E-149 T 14-10-2018 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 SUPERFAMILY SSF68923 15 249 7.85E-95 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 274 282 - T 14-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 13 619 48.763 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 Gene3D G3DSA:3.40.449.10 24 249 2.8E-264 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 Gene3D G3DSA:3.90.228.20 250 617 2.8E-264 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4R43_24470 4e69e28bfe18ed1f78d213c0bf24c6f8 619 PIRSF PIRSF001348 5 619 5.0E-271 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_03000 7cd9187a9d4990bad6e11f431d870bd1 130 Gene3D G3DSA:1.10.1660.10 1 124 2.4E-27 T 14-10-2018 A4R43_03000 7cd9187a9d4990bad6e11f431d870bd1 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.9E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_03000 7cd9187a9d4990bad6e11f431d870bd1 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.9E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_03000 7cd9187a9d4990bad6e11f431d870bd1 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.9E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_03000 7cd9187a9d4990bad6e11f431d870bd1 130 SUPERFAMILY SSF46955 2 115 1.14E-23 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_03000 7cd9187a9d4990bad6e11f431d870bd1 130 SMART SM00422 1 69 5.2E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_03000 7cd9187a9d4990bad6e11f431d870bd1 130 Pfam PF13411 MerR HTH family regulatory protein 2 67 4.2E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00465 7d2efcad6a01378541f690d75a1c99f2 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.9E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_00465 7d2efcad6a01378541f690d75a1c99f2 294 Gene3D G3DSA:3.40.190.10 165 267 7.2E-35 T 14-10-2018 A4R43_00465 7d2efcad6a01378541f690d75a1c99f2 294 SUPERFAMILY SSF46785 2 111 1.87E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00465 7d2efcad6a01378541f690d75a1c99f2 294 Gene3D G3DSA:3.40.190.10 92 280 7.2E-35 T 14-10-2018 A4R43_00465 7d2efcad6a01378541f690d75a1c99f2 294 SUPERFAMILY SSF53850 91 293 4.71E-32 T 14-10-2018 A4R43_00465 7d2efcad6a01378541f690d75a1c99f2 294 Pfam PF03466 LysR substrate binding domain 88 291 2.8E-32 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_00465 7d2efcad6a01378541f690d75a1c99f2 294 Gene3D G3DSA:1.10.10.10 1 91 4.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10395 a1b3cd32e743a3ab3ef130bf842dc33a 336 Gene3D G3DSA:3.40.50.720 152 281 2.0E-81 T 14-10-2018 A4R43_10395 a1b3cd32e743a3ab3ef130bf842dc33a 336 SUPERFAMILY SSF51735 142 302 1.91E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_10395 a1b3cd32e743a3ab3ef130bf842dc33a 336 SUPERFAMILY SSF50129 3 174 3.96E-44 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_10395 a1b3cd32e743a3ab3ef130bf842dc33a 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 1.9E-25 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_10395 a1b3cd32e743a3ab3ef130bf842dc33a 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_10395 a1b3cd32e743a3ab3ef130bf842dc33a 336 Pfam PF00107 Zinc-binding dehydrogenase 176 294 7.7E-16 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_10395 a1b3cd32e743a3ab3ef130bf842dc33a 336 SMART SM00829 8 334 1.2E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_10395 a1b3cd32e743a3ab3ef130bf842dc33a 336 Gene3D G3DSA:3.90.180.10 10 321 2.0E-81 T 14-10-2018 A4R43_28140 bd76b246adc5b6062880c5f122cc397c 304 Gene3D G3DSA:1.10.287.1060 1 97 1.3E-5 T 14-10-2018 A4R43_15895 0ff92df99f818fac262463078b363f1f 311 Pfam PF05175 Methyltransferase small domain 141 252 1.5E-13 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A4R43_15895 0ff92df99f818fac262463078b363f1f 311 Gene3D G3DSA:3.40.50.150 120 303 1.1E-27 T 14-10-2018 A4R43_15895 0ff92df99f818fac262463078b363f1f 311 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 206 212 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4R43_15895 0ff92df99f818fac262463078b363f1f 311 SUPERFAMILY SSF53335 111 253 4.7E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 PIRSF PIRSF037434 3 386 1.2E-74 T 14-10-2018 IPR017205 Signal transduction histidine kinase, ChrS A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 301 385 1.7E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 Pfam PF07730 Histidine kinase 191 258 1.8E-16 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 346 6.0E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 366 6.0E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 385 6.0E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 SMART SM00387 296 386 1.8E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 Gene3D G3DSA:3.30.565.10 258 386 3.8E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25670 fc30cca717e919fb163d87530bd30f86 386 SUPERFAMILY SSF55874 262 385 5.37E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_34830 117dad00f51522d9346436037adbfdf5 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 4.1E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34830 117dad00f51522d9346436037adbfdf5 213 SUPERFAMILY SSF48498 87 195 4.45E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_34830 117dad00f51522d9346436037adbfdf5 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34830 117dad00f51522d9346436037adbfdf5 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34830 117dad00f51522d9346436037adbfdf5 213 SUPERFAMILY SSF46689 9 92 1.65E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_34830 117dad00f51522d9346436037adbfdf5 213 Gene3D G3DSA:1.10.357.10 9 200 6.4E-54 T 14-10-2018 A4R43_11925 397dae687729619622640d97c9e5a854 885 Gene3D G3DSA:1.25.40.10 576 709 7.4E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 SUPERFAMILY SSF48452 750 864 4.05E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 Gene3D G3DSA:1.25.40.10 710 884 1.4E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 SMART SM01043 100 228 4.7E-41 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_11925 397dae687729619622640d97c9e5a854 885 SUPERFAMILY SSF46894 5 95 3.4E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_11925 397dae687729619622640d97c9e5a854 885 SMART SM00862 18 95 6.1E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_11925 397dae687729619622640d97c9e5a854 885 SUPERFAMILY SSF48452 97 243 4.17E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 SUPERFAMILY SSF48452 674 783 7.4E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 95 9.2E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_11925 397dae687729619622640d97c9e5a854 885 SMART SM00028 714 747 180.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 SMART SM00028 639 672 320.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 SMART SM00028 834 867 57.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 SMART SM00028 676 709 0.013 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 PRINTS PR00364 Disease resistance protein signature 267 282 4.1E-7 T 14-10-2018 A4R43_11925 397dae687729619622640d97c9e5a854 885 PRINTS PR00364 Disease resistance protein signature 423 437 4.1E-7 T 14-10-2018 A4R43_11925 397dae687729619622640d97c9e5a854 885 PRINTS PR00364 Disease resistance protein signature 346 360 4.1E-7 T 14-10-2018 A4R43_11925 397dae687729619622640d97c9e5a854 885 Gene3D G3DSA:3.40.50.300 239 391 1.6E-23 T 14-10-2018 A4R43_11925 397dae687729619622640d97c9e5a854 885 Gene3D G3DSA:1.25.40.10 99 238 9.0E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_11925 397dae687729619622640d97c9e5a854 885 Pfam PF03704 Bacterial transcriptional activator domain 112 226 7.9E-33 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_11925 397dae687729619622640d97c9e5a854 885 Gene3D G3DSA:1.10.10.10 3 98 6.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11925 397dae687729619622640d97c9e5a854 885 SUPERFAMILY SSF52540 238 491 8.37E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37850 75bb86f4a499b43b88f6f9bbd11246eb 585 Gene3D G3DSA:3.40.50.300 341 585 5.3E-66 T 14-10-2018 A4R43_37850 75bb86f4a499b43b88f6f9bbd11246eb 585 SUPERFAMILY SSF52540 339 579 1.7E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37850 75bb86f4a499b43b88f6f9bbd11246eb 585 Gene3D G3DSA:1.20.1560.10 8 333 1.3E-58 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_37850 75bb86f4a499b43b88f6f9bbd11246eb 585 Pfam PF00005 ABC transporter 361 510 2.1E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_37850 75bb86f4a499b43b88f6f9bbd11246eb 585 Pfam PF00664 ABC transporter transmembrane region 35 301 5.1E-34 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_37850 75bb86f4a499b43b88f6f9bbd11246eb 585 SMART SM00382 370 556 5.7E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_37850 75bb86f4a499b43b88f6f9bbd11246eb 585 SUPERFAMILY SSF90123 22 334 8.37E-58 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_34335 22b892bc9a38c8040eb69404436fea0d 302 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 19 64 2.5E-12 T 14-10-2018 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region A4R43_41075 a8029ae07fe98a38bc29c5d4f2b3d8ec 283 SUPERFAMILY SSF53474 38 280 2.61E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41075 a8029ae07fe98a38bc29c5d4f2b3d8ec 283 Gene3D G3DSA:3.40.50.1820 30 280 2.1E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41075 a8029ae07fe98a38bc29c5d4f2b3d8ec 283 Pfam PF00756 Putative esterase 60 241 1.3E-9 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 SUPERFAMILY SSF46785 3 71 3.6E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 Gene3D G3DSA:3.40.1410.10 74 233 4.4E-20 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 Gene3D G3DSA:1.10.10.10 2 73 4.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 SMART SM00345 8 67 1.0E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 9.8E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 Pfam PF07702 UTRA domain 92 222 7.6E-14 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 SUPERFAMILY SSF64288 55 232 1.0E-25 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 SMART SM00866 86 226 7.2E-9 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 7.9E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_07445 03b6ada6e0283cdbad5f78b97cf7dd5d 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 7.9E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_34800 5368e62e78b5bfe18fe1bbb7a6b074e4 844 Pfam PF12029 Domain of unknown function (DUF3516) 383 841 6.4E-219 T 14-10-2018 IPR021904 Protein of unknown function DUF3516 A4R43_34800 5368e62e78b5bfe18fe1bbb7a6b074e4 844 Gene3D G3DSA:3.40.50.300 35 211 1.4E-37 T 14-10-2018 A4R43_34800 5368e62e78b5bfe18fe1bbb7a6b074e4 844 SMART SM00490 286 372 5.8E-14 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_34800 5368e62e78b5bfe18fe1bbb7a6b074e4 844 Pfam PF00270 DEAD/DEAH box helicase 42 187 6.6E-9 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_34800 5368e62e78b5bfe18fe1bbb7a6b074e4 844 SUPERFAMILY SSF52540 53 381 6.6E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34800 5368e62e78b5bfe18fe1bbb7a6b074e4 844 SMART SM00487 36 219 5.7E-15 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_34800 5368e62e78b5bfe18fe1bbb7a6b074e4 844 Gene3D G3DSA:3.40.50.300 212 389 3.5E-39 T 14-10-2018 A4R43_34800 5368e62e78b5bfe18fe1bbb7a6b074e4 844 Pfam PF00271 Helicase conserved C-terminal domain 293 372 2.1E-6 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_15195 a4609b9d4cf1814c42518188249dcfee 145 SMART SM00448 8 130 2.9E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15195 a4609b9d4cf1814c42518188249dcfee 145 SUPERFAMILY SSF52172 7 134 1.42E-32 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_15195 a4609b9d4cf1814c42518188249dcfee 145 Pfam PF00072 Response regulator receiver domain 10 130 1.2E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_15195 a4609b9d4cf1814c42518188249dcfee 145 Gene3D G3DSA:3.40.50.2300 2 145 8.9E-37 T 14-10-2018 A4R43_11305 b5929a37ca8e6edce3dd4aefe43b09c7 266 SUPERFAMILY SSF53335 18 244 1.03E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_11305 b5929a37ca8e6edce3dd4aefe43b09c7 266 Pfam PF13649 Methyltransferase domain 44 136 2.4E-12 T 14-10-2018 A4R43_11305 b5929a37ca8e6edce3dd4aefe43b09c7 266 Gene3D G3DSA:3.40.50.150 28 255 1.4E-30 T 14-10-2018 A4R43_27805 f81350f1845093d961b1178c7aabec17 505 Pfam PF04434 SWIM zinc finger 63 83 8.0E-5 T 14-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A4R43_19590 6c712f03eb759c221cfa863663ca7aa3 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 1.4E-54 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4R43_19590 6c712f03eb759c221cfa863663ca7aa3 199 Pfam PF00694 Aconitase C-terminal domain 1 115 1.1E-23 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A4R43_19590 6c712f03eb759c221cfa863663ca7aa3 199 SUPERFAMILY SSF52016 1 186 7.65E-53 T 14-10-2018 A4R43_19590 6c712f03eb759c221cfa863663ca7aa3 199 Gene3D G3DSA:3.20.19.10 1 168 1.2E-66 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A4R43_19590 6c712f03eb759c221cfa863663ca7aa3 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 38.821 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4R43_03275 5bcf2c999c2cdd30fb9f537eaa8dc46c 270 PIRSF PIRSF017393 1 270 2.0E-80 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_03275 5bcf2c999c2cdd30fb9f537eaa8dc46c 270 Gene3D G3DSA:3.40.50.150 1 269 7.4E-96 T 14-10-2018 A4R43_03275 5bcf2c999c2cdd30fb9f537eaa8dc46c 270 Pfam PF04672 S-adenosyl methyltransferase 3 270 3.4E-74 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_03275 5bcf2c999c2cdd30fb9f537eaa8dc46c 270 SUPERFAMILY SSF53335 7 232 4.17E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_26525 2f8759aba5fb1755a561cbf7f3ee2a77 507 Pfam PF06738 Putative threonine/serine exporter 79 321 9.2E-66 T 14-10-2018 IPR010619 Putative threonine/serine exporter A4R43_26525 2f8759aba5fb1755a561cbf7f3ee2a77 507 Pfam PF12821 Threonine/Serine exporter, ThrE 352 473 5.5E-14 T 14-10-2018 IPR024528 Threonine/Serine exporter, ThrE A4R43_22280 26de24449da1c540c5aa16b720ac78e0 175 SUPERFAMILY SSF55811 2 173 5.69E-38 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_22280 26de24449da1c540c5aa16b720ac78e0 175 Pfam PF00293 NUDIX domain 42 149 1.2E-10 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_22280 26de24449da1c540c5aa16b720ac78e0 175 Gene3D G3DSA:3.90.79.10 1 173 9.0E-44 T 14-10-2018 A4R43_19875 7eaca3091177fffda060296af15deebf 204 SUPERFAMILY SSF56784 3 194 7.37E-31 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_19875 7eaca3091177fffda060296af15deebf 204 Gene3D G3DSA:3.40.50.1000 4 195 2.1E-52 T 14-10-2018 IPR023214 HAD superfamily A4R43_19875 7eaca3091177fffda060296af15deebf 204 Pfam PF13419 Haloacid dehalogenase-like hydrolase 74 170 4.6E-8 T 14-10-2018 A4R43_19875 7eaca3091177fffda060296af15deebf 204 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 117 133 3.2E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19875 7eaca3091177fffda060296af15deebf 204 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 86 99 3.2E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19875 7eaca3091177fffda060296af15deebf 204 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 173 3.2E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_19875 7eaca3091177fffda060296af15deebf 204 Gene3D G3DSA:1.10.150.240 14 71 2.1E-52 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_19875 7eaca3091177fffda060296af15deebf 204 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 3 162 7.7E-14 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_35225 81178c15ac3cf08c07e6320e2e481ca3 309 Gene3D G3DSA:3.20.20.70 15 309 8.7E-121 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_35225 81178c15ac3cf08c07e6320e2e481ca3 309 Pfam PF00682 HMGL-like 21 288 2.1E-39 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4R43_35225 81178c15ac3cf08c07e6320e2e481ca3 309 SUPERFAMILY SSF51569 17 303 4.21E-66 T 14-10-2018 A4R43_10980 f113e68df51158f6f7756289e5114402 394 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 342 352 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_10980 f113e68df51158f6f7756289e5114402 394 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 137 148 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A4R43_10980 f113e68df51158f6f7756289e5114402 394 Gene3D G3DSA:3.40.50.200 91 394 6.7E-71 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_10980 f113e68df51158f6f7756289e5114402 394 Pfam PF00082 Subtilase family 132 366 2.2E-44 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_10980 f113e68df51158f6f7756289e5114402 394 PRINTS PR00723 Subtilisin serine protease family (S8) signature 132 151 1.3E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_10980 f113e68df51158f6f7756289e5114402 394 PRINTS PR00723 Subtilisin serine protease family (S8) signature 169 182 1.3E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_10980 f113e68df51158f6f7756289e5114402 394 PRINTS PR00723 Subtilisin serine protease family (S8) signature 341 357 1.3E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_10980 f113e68df51158f6f7756289e5114402 394 SUPERFAMILY SSF52743 120 369 8.25E-67 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_39565 57a13b32480b5d4ff5414f78cf47cc24 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 8.2E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39565 57a13b32480b5d4ff5414f78cf47cc24 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 8.2E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39565 57a13b32480b5d4ff5414f78cf47cc24 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 8.2E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39565 57a13b32480b5d4ff5414f78cf47cc24 118 Gene3D G3DSA:1.10.10.10 4 110 3.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39565 57a13b32480b5d4ff5414f78cf47cc24 118 SUPERFAMILY SSF46785 3 100 1.17E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39565 57a13b32480b5d4ff5414f78cf47cc24 118 SMART SM00418 10 88 5.6E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39565 57a13b32480b5d4ff5414f78cf47cc24 118 Pfam PF12840 Helix-turn-helix domain 9 68 3.2E-16 T 14-10-2018 A4R43_37110 e730f4122bc1f5f71e2662ae1ce2815f 264 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 148 7.4E-24 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_37110 e730f4122bc1f5f71e2662ae1ce2815f 264 Gene3D G3DSA:1.20.120.450 2 151 9.5E-15 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_37110 e730f4122bc1f5f71e2662ae1ce2815f 264 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 225 5.6E-38 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_37110 e730f4122bc1f5f71e2662ae1ce2815f 264 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 5 258 1.4E-90 T 14-10-2018 IPR017518 Conserved hypothetical protein CHP03084 A4R43_37110 e730f4122bc1f5f71e2662ae1ce2815f 264 SUPERFAMILY SSF109854 3 153 7.85E-26 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_24215 f1aaaca584ddcd99b0b53be33918f539 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 8.9E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_24215 f1aaaca584ddcd99b0b53be33918f539 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_24215 f1aaaca584ddcd99b0b53be33918f539 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_24215 f1aaaca584ddcd99b0b53be33918f539 201 Gene3D G3DSA:1.10.357.10 1 193 5.1E-31 T 14-10-2018 A4R43_24215 f1aaaca584ddcd99b0b53be33918f539 201 SUPERFAMILY SSF48498 79 195 8.56E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_24215 f1aaaca584ddcd99b0b53be33918f539 201 SUPERFAMILY SSF46689 3 60 1.32E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 128 140 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 2.1E-29 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 SUPERFAMILY SSF47203 233 386 5.15E-57 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 385 2.7E-49 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 SUPERFAMILY SSF56645 9 247 4.45E-74 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 PIRSF PIRSF016578 7 387 8.7E-23 T 14-10-2018 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 Gene3D G3DSA:2.40.110.10 125 239 1.3E-41 T 14-10-2018 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 121 4.2E-29 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 Gene3D G3DSA:1.10.540.10 13 123 2.0E-37 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_35320 d10663de2b98a8312762eb022e8670b6 387 Gene3D G3DSA:1.20.140.10 240 387 5.6E-55 T 14-10-2018 A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 SUPERFAMILY SSF46785 5 60 3.48E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 SMART SM01134 73 234 1.2E-60 T 14-10-2018 A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 SUPERFAMILY SSF100950 77 235 2.79E-27 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.9E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 Gene3D G3DSA:1.10.10.10 8 96 1.7E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 SMART SM00420 6 58 7.1E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.7E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.7E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 Pfam PF00455 DeoR C terminal sensor domain 77 232 1.8E-45 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_05515 3797b1ea5a93785a48624ec89fdd1fac 259 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_22970 ea1cd3a4824c85867f1cc109d069494e 144 Gene3D G3DSA:2.30.110.10 3 137 2.6E-14 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_22970 ea1cd3a4824c85867f1cc109d069494e 144 SUPERFAMILY SSF50475 5 138 6.92E-16 T 14-10-2018 A4R43_22970 ea1cd3a4824c85867f1cc109d069494e 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 83 3.1E-6 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_35605 117140b12048cbc7b6409fd76801b31f 105 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 49 77 1.2E-9 T 14-10-2018 IPR019933 DivIVA domain A4R43_16520 6d6f6d7bfca483b49fe1d203d9ec7fb5 197 SUPERFAMILY SSF88946 12 111 4.12E-22 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_16520 6d6f6d7bfca483b49fe1d203d9ec7fb5 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 193 2.8E-25 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_16520 6d6f6d7bfca483b49fe1d203d9ec7fb5 197 Pfam PF08281 Sigma-70, region 4 136 189 9.4E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_16520 6d6f6d7bfca483b49fe1d203d9ec7fb5 197 Pfam PF04542 Sigma-70 region 2 38 104 4.6E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_16520 6d6f6d7bfca483b49fe1d203d9ec7fb5 197 Gene3D G3DSA:1.10.10.10 103 196 7.7E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_16520 6d6f6d7bfca483b49fe1d203d9ec7fb5 197 SUPERFAMILY SSF88659 130 193 1.24E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_16520 6d6f6d7bfca483b49fe1d203d9ec7fb5 197 Gene3D G3DSA:1.10.1740.10 18 101 1.2E-27 T 14-10-2018 A4R43_37090 50f351208692d9e5c9de3a08d876fc2d 550 SUPERFAMILY SSF51905 3 514 1.1E-47 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37090 50f351208692d9e5c9de3a08d876fc2d 550 Gene3D G3DSA:3.50.50.60 58 276 4.0E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37090 50f351208692d9e5c9de3a08d876fc2d 550 Gene3D G3DSA:3.30.410.10 126 282 4.0E-32 T 14-10-2018 A4R43_37090 50f351208692d9e5c9de3a08d876fc2d 550 Pfam PF05199 GMC oxidoreductase 450 508 1.8E-13 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_37090 50f351208692d9e5c9de3a08d876fc2d 550 Gene3D G3DSA:3.50.50.60 4 50 1.5E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37090 50f351208692d9e5c9de3a08d876fc2d 550 Gene3D G3DSA:3.50.50.60 421 516 9.0E-18 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37090 50f351208692d9e5c9de3a08d876fc2d 550 Pfam PF00732 GMC oxidoreductase 8 266 1.9E-15 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_38660 4e60c20f25257b92e6891a961aafcca6 110 SMART SM00418 11 90 2.3E-17 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_38660 4e60c20f25257b92e6891a961aafcca6 110 Gene3D G3DSA:1.10.10.10 4 110 7.9E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38660 4e60c20f25257b92e6891a961aafcca6 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.2E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_38660 4e60c20f25257b92e6891a961aafcca6 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.2E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_38660 4e60c20f25257b92e6891a961aafcca6 110 Pfam PF12840 Helix-turn-helix domain 11 67 5.4E-17 T 14-10-2018 A4R43_38660 4e60c20f25257b92e6891a961aafcca6 110 SMART SM00347 14 109 0.0066 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_38660 4e60c20f25257b92e6891a961aafcca6 110 SUPERFAMILY SSF46785 10 104 5.64E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 SMART SM00866 91 235 0.0033 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 Gene3D G3DSA:1.10.10.10 1 71 1.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 SMART SM00345 11 70 7.9E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 SUPERFAMILY SSF64288 58 234 6.0E-21 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 Gene3D G3DSA:3.40.1410.10 79 235 1.4E-19 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 2.7E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 SUPERFAMILY SSF46785 3 72 3.82E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 Pfam PF07702 UTRA domain 99 232 2.6E-12 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 8.4E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_13655 54e23a98acf44dbfee9da74fe72a8e51 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 8.4E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_04165 15b96e17d0774747679f774aec93e0bc 181 SUPERFAMILY SSF54197 40 179 4.02E-41 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_04165 15b96e17d0774747679f774aec93e0bc 181 Pfam PF01230 HIT domain 55 146 1.5E-12 T 14-10-2018 IPR001310 Histidine triad (HIT) protein A4R43_04165 15b96e17d0774747679f774aec93e0bc 181 Gene3D G3DSA:3.30.428.10 6 181 1.3E-57 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_20090 c1eec9f803af695e8e4b9cd1f259de6c 269 Pfam PF03803 Scramblase 89 262 3.8E-16 T 14-10-2018 IPR005552 Scramblase A4R43_20090 c1eec9f803af695e8e4b9cd1f259de6c 269 Pfam PF10708 Protein of unknown function (DUF2510) 7 38 1.1E-10 T 14-10-2018 IPR018929 Domain of unknown function DUF2510 A4R43_20090 c1eec9f803af695e8e4b9cd1f259de6c 269 SUPERFAMILY SSF54518 94 256 1.26E-9 T 14-10-2018 IPR025659 Tubby-like, C-terminal A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 SUPERFAMILY SSF46894 141 213 1.29E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 5.7E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 SMART SM00421 150 207 2.3E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 Pfam PF00072 Response regulator receiver domain 1 113 9.2E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 Gene3D G3DSA:3.40.50.12740 1 213 8.0E-68 T 14-10-2018 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 SUPERFAMILY SSF52172 1 130 3.98E-32 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 4.1E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 4.1E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 4.1E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_23825 b1cd280f419e34594a237eaa79081fdc 215 SMART SM00448 1 112 2.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_32110 8c2125226275a4c0205acd634ea37975 258 SUPERFAMILY SSF52540 5 245 1.73E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_32110 8c2125226275a4c0205acd634ea37975 258 SMART SM00382 29 229 3.5E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_32110 8c2125226275a4c0205acd634ea37975 258 Gene3D G3DSA:3.40.50.300 2 256 1.7E-64 T 14-10-2018 A4R43_32110 8c2125226275a4c0205acd634ea37975 258 Pfam PF00005 ABC transporter 21 176 1.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_32110 8c2125226275a4c0205acd634ea37975 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 9.8E-116 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A4R43_32110 8c2125226275a4c0205acd634ea37975 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_14830 6e8d857da85786f7a670d06fdc658769 414 Pfam PF07690 Major Facilitator Superfamily 33 262 5.0E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_14830 6e8d857da85786f7a670d06fdc658769 414 Gene3D G3DSA:1.20.1250.20 22 406 1.6E-37 T 14-10-2018 A4R43_14830 6e8d857da85786f7a670d06fdc658769 414 SUPERFAMILY SSF103473 25 409 2.88E-45 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_31800 7ab941e2ff27896796744f6afe5b1101 276 SUPERFAMILY SSF141673 4 131 4.45E-27 T 14-10-2018 A4R43_31800 7ab941e2ff27896796744f6afe5b1101 276 Pfam PF03476 MOSC N-terminal beta barrel domain 2 118 3.1E-27 T 14-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 A4R43_31800 7ab941e2ff27896796744f6afe5b1101 276 SUPERFAMILY SSF50800 2 267 8.47E-18 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A4R43_31800 7ab941e2ff27896796744f6afe5b1101 276 Pfam PF03473 MOSC domain 141 265 1.2E-29 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A4R43_38765 004f12e1d81021c083cbbb04279e2b21 198 SUPERFAMILY SSF55166 73 179 3.02E-19 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_38765 004f12e1d81021c083cbbb04279e2b21 198 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 77 180 2.7E-8 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A4R43_38765 004f12e1d81021c083cbbb04279e2b21 198 Gene3D G3DSA:3.30.1380.10 62 186 3.2E-12 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_41370 41380e427df30db494c15036bf0025d7 848 Pfam PF01841 Transglutaminase-like superfamily 447 562 1.3E-25 T 14-10-2018 IPR002931 Transglutaminase-like A4R43_41370 41380e427df30db494c15036bf0025d7 848 SUPERFAMILY SSF54001 443 573 2.1E-33 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_41370 41380e427df30db494c15036bf0025d7 848 SMART SM00460 495 564 1.5E-18 T 14-10-2018 IPR002931 Transglutaminase-like A4R43_41370 41380e427df30db494c15036bf0025d7 848 Pfam PF13559 Domain of unknown function (DUF4129) 752 810 2.8E-5 T 14-10-2018 IPR025403 Domain of unknown function DUF4129 A4R43_41370 41380e427df30db494c15036bf0025d7 848 Gene3D G3DSA:3.10.620.30 410 586 8.0E-24 T 14-10-2018 A4R43_32465 2a4e9977d88b14cf088d254918be87c7 356 Gene3D G3DSA:1.20.1090.10 170 356 2.7E-46 T 14-10-2018 A4R43_32465 2a4e9977d88b14cf088d254918be87c7 356 SUPERFAMILY SSF56796 6 354 1.7E-94 T 14-10-2018 A4R43_32465 2a4e9977d88b14cf088d254918be87c7 356 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 347 1.2E-93 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A4R43_32465 2a4e9977d88b14cf088d254918be87c7 356 Gene3D G3DSA:3.40.50.1970 2 168 3.2E-45 T 14-10-2018 A4R43_32465 2a4e9977d88b14cf088d254918be87c7 356 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 244 264 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A4R43_32465 2a4e9977d88b14cf088d254918be87c7 356 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 157 185 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A4R43_00575 52e7e242c5b1ec3a35a6a75c352b4404 456 Pfam PF00324 Amino acid permease 18 451 9.8E-104 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A4R43_00575 52e7e242c5b1ec3a35a6a75c352b4404 456 PIRSF PIRSF006060 1 454 1.5E-66 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_00575 52e7e242c5b1ec3a35a6a75c352b4404 456 Gene3D G3DSA:1.20.1740.10 13 455 2.7E-62 T 14-10-2018 A4R43_27685 967a506b2e5c9d00a147b33170dc9600 302 Pfam PF00005 ABC transporter 20 159 1.3E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_27685 967a506b2e5c9d00a147b33170dc9600 302 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_27685 967a506b2e5c9d00a147b33170dc9600 302 SUPERFAMILY SSF52540 4 219 4.05E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27685 967a506b2e5c9d00a147b33170dc9600 302 Pfam PF13732 Domain of unknown function (DUF4162) 212 289 2.6E-7 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 A4R43_27685 967a506b2e5c9d00a147b33170dc9600 302 SMART SM00382 29 206 2.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_27685 967a506b2e5c9d00a147b33170dc9600 302 Gene3D G3DSA:3.40.50.300 1 230 1.3E-56 T 14-10-2018 A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 191 0.0089 T 14-10-2018 A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 Pfam PF00106 short chain dehydrogenase 5 197 1.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 Gene3D G3DSA:3.40.50.720 3 247 2.5E-52 T 14-10-2018 A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 SUPERFAMILY SSF51735 5 220 2.91E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.2E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.2E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.2E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.2E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19030 f06d343c5c1d81deeed86034a320d074 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.2E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_27415 2e589e0c3c28e850f2a55528d8a7d488 199 Gene3D G3DSA:3.40.50.300 2 180 2.5E-19 T 14-10-2018 A4R43_27415 2e589e0c3c28e850f2a55528d8a7d488 199 SUPERFAMILY SSF52540 14 158 4.8E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29525 9c5b0f23ebfe12d269e595dc2397a42f 177 SMART SM00866 29 170 3.7E-19 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_29525 9c5b0f23ebfe12d269e595dc2397a42f 177 SUPERFAMILY SSF64288 24 175 2.57E-32 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_29525 9c5b0f23ebfe12d269e595dc2397a42f 177 Gene3D G3DSA:3.40.1410.10 12 173 3.1E-40 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_29525 9c5b0f23ebfe12d269e595dc2397a42f 177 Pfam PF07702 UTRA domain 34 167 2.5E-24 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_21085 0f05454e3f122c54f0d4e513adb4be5d 493 Pfam PF00743 Flavin-binding monooxygenase-like 9 350 4.1E-21 T 14-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4R43_21085 0f05454e3f122c54f0d4e513adb4be5d 493 Gene3D G3DSA:3.50.50.60 307 487 1.8E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21085 0f05454e3f122c54f0d4e513adb4be5d 493 Gene3D G3DSA:3.50.50.60 1 168 8.4E-61 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21085 0f05454e3f122c54f0d4e513adb4be5d 493 SUPERFAMILY SSF51905 9 474 1.28E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21085 0f05454e3f122c54f0d4e513adb4be5d 493 SUPERFAMILY SSF51905 279 477 5.05E-17 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_39020 8c8725615fef3b3ad8f2cc517b5a7ffe 820 Gene3D G3DSA:1.10.10.10 678 818 4.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39020 8c8725615fef3b3ad8f2cc517b5a7ffe 820 SMART SM00421 754 811 1.1E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39020 8c8725615fef3b3ad8f2cc517b5a7ffe 820 ProSitePatterns PS00622 LuxR-type HTH domain signature. 771 798 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39020 8c8725615fef3b3ad8f2cc517b5a7ffe 820 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 787 799 1.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39020 8c8725615fef3b3ad8f2cc517b5a7ffe 820 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 757 771 1.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39020 8c8725615fef3b3ad8f2cc517b5a7ffe 820 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 771 787 1.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39020 8c8725615fef3b3ad8f2cc517b5a7ffe 820 SUPERFAMILY SSF46894 751 813 2.01E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_39020 8c8725615fef3b3ad8f2cc517b5a7ffe 820 Pfam PF00196 Bacterial regulatory proteins, luxR family 756 808 2.4E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_24455 474961b39379c1678e0e82d6819e3c06 670 Pfam PF07693 KAP family P-loop domain 25 385 3.6E-39 T 14-10-2018 IPR011646 KAP family P-loop domain A4R43_24455 474961b39379c1678e0e82d6819e3c06 670 SUPERFAMILY SSF52540 10 323 2.36E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16355 2f77cd76f04a49198d7528663ae2a522 278 Gene3D G3DSA:3.90.79.10 14 138 3.2E-23 T 14-10-2018 A4R43_16355 2f77cd76f04a49198d7528663ae2a522 278 SUPERFAMILY SSF55811 9 146 1.9E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_16355 2f77cd76f04a49198d7528663ae2a522 278 Pfam PF00293 NUDIX domain 19 129 7.1E-21 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_33840 8006745be173ad8d160c6b2df25bd998 218 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 8 209 3.4E-89 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33840 8006745be173ad8d160c6b2df25bd998 218 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 6 212 39.628 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33840 8006745be173ad8d160c6b2df25bd998 218 Gene3D G3DSA:2.40.30.10 124 215 5.3E-14 T 14-10-2018 A4R43_33840 8006745be173ad8d160c6b2df25bd998 218 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site A4R43_33840 8006745be173ad8d160c6b2df25bd998 218 Gene3D G3DSA:2.40.50.620 37 101 9.6E-19 T 14-10-2018 A4R43_33840 8006745be173ad8d160c6b2df25bd998 218 Pfam PF00297 Ribosomal protein L3 100 187 4.9E-17 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33840 8006745be173ad8d160c6b2df25bd998 218 SUPERFAMILY SSF50447 5 213 3.18E-80 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_05350 da603e739878f8209c29b06f7b764d60 150 Gene3D G3DSA:3.10.129.10 1 149 3.4E-50 T 14-10-2018 A4R43_05350 da603e739878f8209c29b06f7b764d60 150 Pfam PF01575 MaoC like domain 10 121 4.4E-27 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_05350 da603e739878f8209c29b06f7b764d60 150 SUPERFAMILY SSF54637 12 148 2.21E-38 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_39125 2cd6127b821f7c5d5a528b8a6ec254d5 290 SUPERFAMILY SSF52266 32 287 2.33E-58 T 14-10-2018 A4R43_39125 2cd6127b821f7c5d5a528b8a6ec254d5 290 Gene3D G3DSA:3.40.50.1110 29 288 4.1E-67 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_39125 2cd6127b821f7c5d5a528b8a6ec254d5 290 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 35 276 1.4E-24 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_40080 3c951254673cea82fddcbdf0723784ab 142 SMART SM00347 26 125 2.8E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40080 3c951254673cea82fddcbdf0723784ab 142 SUPERFAMILY SSF46785 5 141 1.12E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40080 3c951254673cea82fddcbdf0723784ab 142 Pfam PF12802 MarR family 33 90 2.1E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40080 3c951254673cea82fddcbdf0723784ab 142 Gene3D G3DSA:1.10.10.10 1 142 3.1E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25435 dffb27a33e5b3c3ce70866df540545a7 141 Gene3D G3DSA:1.10.101.10 55 127 4.1E-16 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_25435 dffb27a33e5b3c3ce70866df540545a7 141 SUPERFAMILY SSF47090 60 126 3.14E-13 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_25435 dffb27a33e5b3c3ce70866df540545a7 141 Pfam PF01471 Putative peptidoglycan binding domain 66 123 2.5E-10 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_01320 065779085df726c16ea8fd5598aba2ca 114 Pfam PF00196 Bacterial regulatory proteins, luxR family 46 89 2.0E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_01320 065779085df726c16ea8fd5598aba2ca 114 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 50 66 1.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_01320 065779085df726c16ea8fd5598aba2ca 114 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 66 78 1.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_01320 065779085df726c16ea8fd5598aba2ca 114 Gene3D G3DSA:1.10.10.10 45 101 1.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01320 065779085df726c16ea8fd5598aba2ca 114 SUPERFAMILY SSF46894 48 92 5.1E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_01320 065779085df726c16ea8fd5598aba2ca 114 ProSitePatterns PS00622 LuxR-type HTH domain signature. 50 77 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_01320 065779085df726c16ea8fd5598aba2ca 114 SMART SM00421 41 90 9.0E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33075 bb2f82ba62de4f106da7a8d31f506907 427 SUPERFAMILY SSF51905 10 382 4.46E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_33075 bb2f82ba62de4f106da7a8d31f506907 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 8.5E-15 T 14-10-2018 A4R43_33075 bb2f82ba62de4f106da7a8d31f506907 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 8.5E-15 T 14-10-2018 A4R43_33075 bb2f82ba62de4f106da7a8d31f506907 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 8.5E-15 T 14-10-2018 A4R43_33075 bb2f82ba62de4f106da7a8d31f506907 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 8.5E-15 T 14-10-2018 A4R43_33075 bb2f82ba62de4f106da7a8d31f506907 427 Pfam PF01494 FAD binding domain 9 182 1.7E-14 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_33075 bb2f82ba62de4f106da7a8d31f506907 427 Gene3D G3DSA:3.50.50.60 4 388 4.3E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_33075 bb2f82ba62de4f106da7a8d31f506907 427 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 11 332 2.8E-70 T 14-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A4R43_22165 3431caf25ea472530141ba8d6a496654 222 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 19 197 8.0E-6 T 14-10-2018 IPR009830 LppX/LprAFG lipoprotein family A4R43_22165 3431caf25ea472530141ba8d6a496654 222 Pfam PF07161 LppX_LprAFG lipoprotein 31 200 1.5E-22 T 14-10-2018 IPR009830 LppX/LprAFG lipoprotein family A4R43_22165 3431caf25ea472530141ba8d6a496654 222 Gene3D G3DSA:2.50.20.20 22 215 1.5E-37 T 14-10-2018 A4R43_22165 3431caf25ea472530141ba8d6a496654 222 SUPERFAMILY SSF89392 28 203 4.32E-20 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4R43_37120 9001c20a3bcc30623002c3c087fe6cf0 516 Gene3D G3DSA:3.40.50.150 250 494 5.5E-28 T 14-10-2018 A4R43_37120 9001c20a3bcc30623002c3c087fe6cf0 516 SUPERFAMILY SSF53335 342 512 2.87E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_37120 9001c20a3bcc30623002c3c087fe6cf0 516 Pfam PF13649 Methyltransferase domain 358 449 2.5E-14 T 14-10-2018 A4R43_08405 eccc1e5dc57ea577633cdffaebcbe8a0 262 Gene3D G3DSA:3.20.20.190 15 257 2.5E-61 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A4R43_08405 eccc1e5dc57ea577633cdffaebcbe8a0 262 SUPERFAMILY SSF51695 14 253 3.35E-53 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A4R43_08405 eccc1e5dc57ea577633cdffaebcbe8a0 262 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 192 247 6.6E-9 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A4R43_08405 eccc1e5dc57ea577633cdffaebcbe8a0 262 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 20 146 8.4E-21 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A4R43_19480 d5fee5fde597d9e62cf1739713fd0691 390 Pfam PF05139 Erythromycin esterase 41 384 2.8E-50 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 A4R43_19480 d5fee5fde597d9e62cf1739713fd0691 390 Gene3D G3DSA:3.40.1660.10 5 383 6.9E-47 T 14-10-2018 A4R43_19480 d5fee5fde597d9e62cf1739713fd0691 390 Gene3D G3DSA:3.30.1870.10 43 116 6.9E-47 T 14-10-2018 A4R43_19480 d5fee5fde597d9e62cf1739713fd0691 390 Gene3D G3DSA:1.20.1440.30 117 258 6.9E-47 T 14-10-2018 A4R43_19480 d5fee5fde597d9e62cf1739713fd0691 390 SUPERFAMILY SSF159501 3 387 6.8E-66 T 14-10-2018 A4R43_12610 eb3bf4e63cb485730b181d9db77f86cc 183 Pfam PF01575 MaoC like domain 17 120 3.0E-20 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_12610 eb3bf4e63cb485730b181d9db77f86cc 183 Gene3D G3DSA:3.10.129.10 7 152 7.5E-41 T 14-10-2018 A4R43_12610 eb3bf4e63cb485730b181d9db77f86cc 183 SUPERFAMILY SSF54637 14 149 1.71E-30 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 SUPERFAMILY SSF47203 231 381 7.57E-50 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 8.8E-48 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 SUPERFAMILY SSF56645 2 246 1.28E-79 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 Gene3D G3DSA:1.20.140.10 240 383 7.3E-50 T 14-10-2018 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 Gene3D G3DSA:1.10.540.10 1 121 3.0E-39 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 221 1.0E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 Gene3D G3DSA:2.40.110.10 122 239 1.1E-36 T 14-10-2018 A4R43_22915 d45df691dc348476a2e9d24dfd10f5e8 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 2.2E-33 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_20025 9bf61fa0f12888c3b0578e7030b200a7 399 SUPERFAMILY SSF63829 105 287 4.74E-13 T 14-10-2018 A4R43_20025 9bf61fa0f12888c3b0578e7030b200a7 399 Gene3D G3DSA:2.120.10.30 63 390 8.1E-44 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_20025 9bf61fa0f12888c3b0578e7030b200a7 399 Pfam PF07995 Glucose / Sorbosone dehydrogenase 109 288 8.9E-20 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_15780 c80d1fdf693086fa9bcc2cd8ef753885 585 Gene3D G3DSA:3.40.50.300 22 189 3.7E-21 T 14-10-2018 A4R43_15780 c80d1fdf693086fa9bcc2cd8ef753885 585 Gene3D G3DSA:3.40.50.300 208 411 1.0E-13 T 14-10-2018 A4R43_15780 c80d1fdf693086fa9bcc2cd8ef753885 585 SMART SM00487 24 206 5.6E-11 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_15780 c80d1fdf693086fa9bcc2cd8ef753885 585 SUPERFAMILY SSF52540 43 388 2.8E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15780 c80d1fdf693086fa9bcc2cd8ef753885 585 Pfam PF04851 Type III restriction enzyme, res subunit 28 180 4.6E-13 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4R43_26140 08e5a7965134db34bc143c137277c33e 550 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 87 510 9.2E-211 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4R43_26140 08e5a7965134db34bc143c137277c33e 550 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 86 512 96.928 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4R43_26140 08e5a7965134db34bc143c137277c33e 550 Gene3D G3DSA:3.20.20.540 129 443 3.2E-151 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4R43_26140 08e5a7965134db34bc143c137277c33e 550 Pfam PF01964 Radical SAM ThiC family 87 507 1.7E-200 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4R43_26140 08e5a7965134db34bc143c137277c33e 550 Pfam PF13667 ThiC-associated domain 21 84 1.3E-15 T 14-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4R43_09350 c444b5215466ac6983ff60a3c5492675 399 SUPERFAMILY SSF51905 5 354 1.91E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09350 c444b5215466ac6983ff60a3c5492675 399 Gene3D G3DSA:3.30.9.50 41 274 8.4E-65 T 14-10-2018 A4R43_09350 c444b5215466ac6983ff60a3c5492675 399 Pfam PF01494 FAD binding domain 5 343 4.2E-21 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_09350 c444b5215466ac6983ff60a3c5492675 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.4E-14 T 14-10-2018 A4R43_09350 c444b5215466ac6983ff60a3c5492675 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.4E-14 T 14-10-2018 A4R43_09350 c444b5215466ac6983ff60a3c5492675 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 1.4E-14 T 14-10-2018 A4R43_09350 c444b5215466ac6983ff60a3c5492675 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 1.4E-14 T 14-10-2018 A4R43_09350 c444b5215466ac6983ff60a3c5492675 399 Gene3D G3DSA:3.50.50.60 8 345 8.4E-65 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13500 b6994f2a36a5af87346d0b430a687b4d 426 SUPERFAMILY SSF51338 4 400 2.79E-18 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_13500 b6994f2a36a5af87346d0b430a687b4d 426 SUPERFAMILY SSF51556 46 358 3.85E-22 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_13500 b6994f2a36a5af87346d0b430a687b4d 426 Gene3D G3DSA:2.30.40.10 1 61 2.3E-16 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_13500 b6994f2a36a5af87346d0b430a687b4d 426 Gene3D G3DSA:2.30.40.10 359 374 2.7E-47 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_13500 b6994f2a36a5af87346d0b430a687b4d 426 Gene3D G3DSA:3.20.20.140 75 358 2.7E-47 T 14-10-2018 A4R43_13500 b6994f2a36a5af87346d0b430a687b4d 426 Pfam PF07969 Amidohydrolase family 73 399 4.1E-35 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_00515 e433798f181c0e3328ee9e4b3f0109d3 161 Gene3D G3DSA:1.10.10.10 2 84 3.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00515 e433798f181c0e3328ee9e4b3f0109d3 161 SUPERFAMILY SSF46785 12 143 9.97E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00515 e433798f181c0e3328ee9e4b3f0109d3 161 Pfam PF12840 Helix-turn-helix domain 12 63 2.0E-14 T 14-10-2018 A4R43_00515 e433798f181c0e3328ee9e4b3f0109d3 161 SMART SM00418 11 105 0.0015 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 SUPERFAMILY SSF46977 446 595 8.5E-46 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 PIRSF PIRSF000171 1 561 3.0E-44 T 14-10-2018 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 SUPERFAMILY SSF51905 2 432 2.15E-72 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 Pfam PF00890 FAD binding domain 7 400 2.5E-112 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 595 3.0E-286 T 14-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 Gene3D G3DSA:3.50.50.60 7 411 1.6E-156 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 Gene3D G3DSA:3.90.700.10 246 349 1.6E-156 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 6.9E-6 T 14-10-2018 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 6.9E-6 T 14-10-2018 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 Gene3D G3DSA:1.20.58.100 427 541 5.4E-36 T 14-10-2018 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 595 3.6E-42 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 6.3E-5 T 14-10-2018 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.3E-5 T 14-10-2018 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 595 4.6E-248 T 14-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34735 4a29e68c4219ec0df33f8ebfb02bd09f 595 SUPERFAMILY SSF56425 236 354 2.99E-40 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_13065 a3e40d3169e252fb0099a4aaf4daa03b 306 PIRSF PIRSF007580 16 305 4.8E-95 T 14-10-2018 IPR016516 Uncharacterised conserved protein UCP07580 A4R43_13065 a3e40d3169e252fb0099a4aaf4daa03b 306 Pfam PF10118 Predicted metal-dependent hydrolase 30 285 1.2E-71 T 14-10-2018 IPR016516 Uncharacterised conserved protein UCP07580 A4R43_28945 02e62b4436798336e88a763bc5095ce0 211 SUPERFAMILY SSF46689 20 93 5.99E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_28945 02e62b4436798336e88a763bc5095ce0 211 Gene3D G3DSA:1.10.357.10 25 210 2.2E-58 T 14-10-2018 A4R43_28945 02e62b4436798336e88a763bc5095ce0 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 42 73 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_28945 02e62b4436798336e88a763bc5095ce0 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 76 9.7E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28945 02e62b4436798336e88a763bc5095ce0 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 9.6E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28945 02e62b4436798336e88a763bc5095ce0 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 9.6E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08175 31458371d317081cc7db75c698ab31c4 330 Gene3D G3DSA:1.10.10.10 6 67 1.5E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08175 31458371d317081cc7db75c698ab31c4 330 Pfam PF13280 WYL domain 142 313 1.0E-27 T 14-10-2018 IPR026881 WYL domain A4R43_08175 31458371d317081cc7db75c698ab31c4 330 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_08175 31458371d317081cc7db75c698ab31c4 330 SUPERFAMILY SSF46785 6 64 6.75E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08175 31458371d317081cc7db75c698ab31c4 330 PIRSF PIRSF016838 2 323 1.6E-20 T 14-10-2018 IPR028349 Protein PafC A4R43_08175 31458371d317081cc7db75c698ab31c4 330 Pfam PF08279 HTH domain 9 64 5.9E-16 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 2.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 Pfam PF01047 MarR family 45 98 6.0E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 Gene3D G3DSA:1.10.10.10 4 150 2.4E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 SUPERFAMILY SSF46785 41 152 2.04E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_29855 7073e7a4636df3dcc1d3e5f8dc12c038 164 SMART SM00347 29 134 1.9E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40305 aa430ac74e561c14a6e72604e56a5001 283 Pfam PF13560 Helix-turn-helix domain 5 84 6.1E-14 T 14-10-2018 A4R43_40305 aa430ac74e561c14a6e72604e56a5001 283 SMART SM00530 9 81 5.8E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_40305 aa430ac74e561c14a6e72604e56a5001 283 Gene3D G3DSA:3.30.450.180 104 278 9.7E-11 T 14-10-2018 A4R43_40305 aa430ac74e561c14a6e72604e56a5001 283 Gene3D G3DSA:1.10.260.40 24 90 1.4E-5 T 14-10-2018 A4R43_40305 aa430ac74e561c14a6e72604e56a5001 283 SUPERFAMILY SSF47413 27 78 1.13E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_12095 65fdba74102dd89b28913f0445e3b9d3 462 Gene3D G3DSA:1.10.510.10 96 280 6.7E-47 T 14-10-2018 A4R43_12095 65fdba74102dd89b28913f0445e3b9d3 462 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_12095 65fdba74102dd89b28913f0445e3b9d3 462 SUPERFAMILY SSF56112 2 355 4.05E-71 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_12095 65fdba74102dd89b28913f0445e3b9d3 462 Gene3D G3DSA:3.30.200.20 1 93 3.0E-24 T 14-10-2018 A4R43_12095 65fdba74102dd89b28913f0445e3b9d3 462 Pfam PF00069 Protein kinase domain 6 261 2.9E-47 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_12095 65fdba74102dd89b28913f0445e3b9d3 462 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 12 35 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_12095 65fdba74102dd89b28913f0445e3b9d3 462 PIRSF PIRSF000654 53 276 1.2E-26 T 14-10-2018 A4R43_12095 65fdba74102dd89b28913f0445e3b9d3 462 SMART SM00220 6 268 7.4E-59 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_03780 e20be05ef677d13093f6b5294f055b21 218 SUPERFAMILY SSF56784 2 211 1.3E-36 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_03780 e20be05ef677d13093f6b5294f055b21 218 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 2 214 1.3E-72 T 14-10-2018 IPR022468 Phosphonatase-like hydrolase A4R43_03780 e20be05ef677d13093f6b5294f055b21 218 Gene3D G3DSA:3.40.50.1000 2 192 3.4E-32 T 14-10-2018 IPR023214 HAD superfamily A4R43_03780 e20be05ef677d13093f6b5294f055b21 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 183 7.4E-17 T 14-10-2018 A4R43_03780 e20be05ef677d13093f6b5294f055b21 218 Gene3D G3DSA:1.10.150.240 19 81 3.4E-32 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_13270 f236f2d4937648250452e6a9d39bccc0 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 2.2E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13270 f236f2d4937648250452e6a9d39bccc0 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.2E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13270 f236f2d4937648250452e6a9d39bccc0 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 2.2E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13270 f236f2d4937648250452e6a9d39bccc0 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 2.2E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13270 f236f2d4937648250452e6a9d39bccc0 267 Gene3D G3DSA:3.40.50.1820 3 263 3.0E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13270 f236f2d4937648250452e6a9d39bccc0 267 Pfam PF00561 alpha/beta hydrolase fold 23 248 6.9E-22 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13270 f236f2d4937648250452e6a9d39bccc0 267 SUPERFAMILY SSF53474 3 260 5.18E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_39395 a2f1a11f1950269f25e9b3ffeeefc542 286 SUPERFAMILY SSF103481 41 140 1.44E-12 T 14-10-2018 A4R43_39395 a2f1a11f1950269f25e9b3ffeeefc542 286 Pfam PF00892 EamA-like transporter family 150 283 2.2E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_39395 a2f1a11f1950269f25e9b3ffeeefc542 286 Pfam PF00892 EamA-like transporter family 5 136 3.7E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_39395 a2f1a11f1950269f25e9b3ffeeefc542 286 SUPERFAMILY SSF103481 193 284 6.8E-11 T 14-10-2018 A4R43_02970 fb8c394f36f5c09c3fa58fb6f23bf870 437 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 346 5.0E-12 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_02970 fb8c394f36f5c09c3fa58fb6f23bf870 437 SUPERFAMILY SSF51905 1 388 9.72E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02970 fb8c394f36f5c09c3fa58fb6f23bf870 437 Gene3D G3DSA:3.50.50.60 2 393 4.9E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02970 fb8c394f36f5c09c3fa58fb6f23bf870 437 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 6.0E-7 T 14-10-2018 A4R43_02970 fb8c394f36f5c09c3fa58fb6f23bf870 437 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 367 6.0E-7 T 14-10-2018 A4R43_20830 2fc9a75f9b3f7d22f137630d73e4f94f 478 Pfam PF13520 Amino acid permease 30 444 3.8E-53 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_20830 2fc9a75f9b3f7d22f137630d73e4f94f 478 PIRSF PIRSF006060 4 478 3.4E-92 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_20830 2fc9a75f9b3f7d22f137630d73e4f94f 478 Gene3D G3DSA:1.20.1740.10 21 477 2.6E-113 T 14-10-2018 A4R43_30605 7615ed2c26746f042c4bb75ca8872153 142 Pfam PF13630 SdpI/YhfL protein family 27 90 2.5E-8 T 14-10-2018 IPR025962 SdpI/YhfL protein family A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 SUPERFAMILY SSF50129 1 181 7.61E-53 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 Gene3D G3DSA:3.90.180.10 9 330 8.1E-95 T 14-10-2018 A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 Gene3D G3DSA:3.40.50.720 159 295 8.1E-95 T 14-10-2018 A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 Pfam PF00107 Zinc-binding dehydrogenase 182 310 3.0E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 20 8.4E-7 T 14-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 SUPERFAMILY SSF51735 146 313 1.5E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 SMART SM00829 8 346 1.8E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_41770 f7f23b9ab31a8a85533b86b79f868607 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 141 6.6E-34 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_01840 346b5979916b26a55cfcc691314c0938 297 Gene3D G3DSA:1.10.10.10 110 166 8.7E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01840 346b5979916b26a55cfcc691314c0938 297 Gene3D G3DSA:3.10.450.50 173 292 1.0E-8 T 14-10-2018 A4R43_01840 346b5979916b26a55cfcc691314c0938 297 Pfam PF04542 Sigma-70 region 2 11 74 1.3E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_01840 346b5979916b26a55cfcc691314c0938 297 SUPERFAMILY SSF88659 105 163 1.38E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_01840 346b5979916b26a55cfcc691314c0938 297 SUPERFAMILY SSF88946 7 90 1.69E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_01840 346b5979916b26a55cfcc691314c0938 297 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 163 1.3E-18 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_01840 346b5979916b26a55cfcc691314c0938 297 SUPERFAMILY SSF54427 173 289 2.25E-14 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_01840 346b5979916b26a55cfcc691314c0938 297 Gene3D G3DSA:1.10.1740.10 2 100 3.9E-9 T 14-10-2018 A4R43_01840 346b5979916b26a55cfcc691314c0938 297 Pfam PF08281 Sigma-70, region 4 111 161 5.6E-9 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_21340 60d4d06b5444d9bbfc2ad6f9e29292cc 361 Pfam PF00480 ROK family 152 238 7.6E-7 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_21340 60d4d06b5444d9bbfc2ad6f9e29292cc 361 Gene3D G3DSA:3.30.420.40 88 203 7.7E-22 T 14-10-2018 A4R43_21340 60d4d06b5444d9bbfc2ad6f9e29292cc 361 Gene3D G3DSA:3.30.420.40 204 322 7.7E-22 T 14-10-2018 A4R43_21340 60d4d06b5444d9bbfc2ad6f9e29292cc 361 Pfam PF13412 Winged helix-turn-helix DNA-binding 15 58 3.8E-8 T 14-10-2018 A4R43_21340 60d4d06b5444d9bbfc2ad6f9e29292cc 361 Gene3D G3DSA:1.10.10.10 2 75 1.2E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21340 60d4d06b5444d9bbfc2ad6f9e29292cc 361 SUPERFAMILY SSF53067 102 353 6.79E-21 T 14-10-2018 A4R43_21340 60d4d06b5444d9bbfc2ad6f9e29292cc 361 SUPERFAMILY SSF46785 12 74 8.67E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_21690 c423a37f259126ec23277525674d8e04 108 Pfam PF01809 Haemolytic domain 17 82 4.8E-22 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A4R43_21690 c423a37f259126ec23277525674d8e04 108 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 19 88 3.9E-19 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A4R43_21690 c423a37f259126ec23277525674d8e04 108 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 30 82 1.0E-12 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A4R43_21690 c423a37f259126ec23277525674d8e04 108 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 15 83 20.43 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A4R43_21690 c423a37f259126ec23277525674d8e04 108 SMART SM01234 15 82 7.1E-28 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A4R43_19905 3f4fecc2b5506ea05f0fb3cfbf4aa86b 382 Pfam PF12671 Putative amidase domain 209 362 4.9E-17 T 14-10-2018 IPR024301 Putative amidase domain A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 SUPERFAMILY SSF46689 225 270 1.39E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 SUPERFAMILY SSF46689 179 222 9.86E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 Gene3D G3DSA:1.10.10.60 231 271 7.8E-11 T 14-10-2018 A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 225 266 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 Pfam PF12833 Helix-turn-helix domain 194 270 3.8E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 SMART SM00342 188 270 7.6E-26 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 Gene3D G3DSA:1.10.10.60 172 230 1.9E-14 T 14-10-2018 A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 SUPERFAMILY SSF51215 28 139 2.22E-14 T 14-10-2018 IPR037923 Transcription regulator HTH-like A4R43_23445 c87b390473e887bb1023d1ed5bb59e27 271 Pfam PF02311 AraC-like ligand binding domain 27 142 8.4E-14 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4R43_13410 296db14322d043b429cf9df96d7ca429 566 SMART SM00382 360 539 3.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_13410 296db14322d043b429cf9df96d7ca429 566 SUPERFAMILY SSF52540 325 557 8.4E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13410 296db14322d043b429cf9df96d7ca429 566 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 288 4.3E-18 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_13410 296db14322d043b429cf9df96d7ca429 566 Pfam PF00005 ABC transporter 352 489 3.4E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_13410 296db14322d043b429cf9df96d7ca429 566 Gene3D G3DSA:3.40.50.300 333 560 2.2E-44 T 14-10-2018 A4R43_13410 296db14322d043b429cf9df96d7ca429 566 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 539 561 3.3E-5 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4R43_29265 bd24123854e766d196762bf4285c206e 707 Pfam PF00931 NB-ARC domain 60 307 3.6E-6 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_29265 bd24123854e766d196762bf4285c206e 707 PRINTS PR00364 Disease resistance protein signature 237 251 4.5E-5 T 14-10-2018 A4R43_29265 bd24123854e766d196762bf4285c206e 707 PRINTS PR00364 Disease resistance protein signature 72 87 4.5E-5 T 14-10-2018 A4R43_29265 bd24123854e766d196762bf4285c206e 707 Gene3D G3DSA:3.40.50.300 36 194 9.1E-23 T 14-10-2018 A4R43_29265 bd24123854e766d196762bf4285c206e 707 Gene3D G3DSA:1.25.40.10 494 696 2.6E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_29265 bd24123854e766d196762bf4285c206e 707 SUPERFAMILY SSF52540 36 299 9.91E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29265 bd24123854e766d196762bf4285c206e 707 SUPERFAMILY SSF48452 497 680 4.74E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_29265 bd24123854e766d196762bf4285c206e 707 SMART SM00028 527 560 5.9 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_29265 bd24123854e766d196762bf4285c206e 707 SMART SM00028 649 682 26.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_29265 bd24123854e766d196762bf4285c206e 707 SMART SM00028 487 520 180.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_38190 b52aa5eb3f853e15ddaf83b22479a2f9 97 Pfam PF02467 Transcription factor WhiB 17 86 9.7E-23 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain A4R43_38190 b52aa5eb3f853e15ddaf83b22479a2f9 97 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 93 19.073 T 14-10-2018 IPR003482 Transcription factor WhiB A4R43_21135 59b7f3c3af5dc591cdf8eb994a2f4c29 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 4.3E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_21135 59b7f3c3af5dc591cdf8eb994a2f4c29 228 SUPERFAMILY SSF52172 5 178 3.17E-41 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_21135 59b7f3c3af5dc591cdf8eb994a2f4c29 228 Gene3D G3DSA:1.10.10.10 127 228 4.7E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21135 59b7f3c3af5dc591cdf8eb994a2f4c29 228 SMART SM00448 3 117 4.2E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_21135 59b7f3c3af5dc591cdf8eb994a2f4c29 228 Gene3D G3DSA:3.40.50.2300 1 126 3.1E-36 T 14-10-2018 A4R43_21135 59b7f3c3af5dc591cdf8eb994a2f4c29 228 Pfam PF00072 Response regulator receiver domain 6 118 2.1E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_21135 59b7f3c3af5dc591cdf8eb994a2f4c29 228 SMART SM00862 150 224 2.7E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_24775 723a16dbc447fcc1a009474f6080df9d 876 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 29 837 2.0E-258 T 14-10-2018 IPR018752 Uncharacterised protein family UPF0753 A4R43_24775 723a16dbc447fcc1a009474f6080df9d 876 Hamap MF_01871 UPF0753 protein . 23 852 23.038 T 14-10-2018 IPR018752 Uncharacterised protein family UPF0753 A4R43_24895 a0d58cd548fe549200e7f6873acf9c00 706 Pfam PF00589 Phage integrase family 380 550 1.8E-11 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_24895 a0d58cd548fe549200e7f6873acf9c00 706 SUPERFAMILY SSF56349 378 563 1.21E-21 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_24895 a0d58cd548fe549200e7f6873acf9c00 706 Gene3D G3DSA:1.10.443.10 366 564 1.5E-19 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_19770 c9275380bee833b36840211439a8b117 156 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 95 2.2E-20 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_19770 c9275380bee833b36840211439a8b117 156 Gene3D G3DSA:1.20.1290.10 1 146 1.8E-42 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_19770 c9275380bee833b36840211439a8b117 156 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 80 1.8E-21 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_19770 c9275380bee833b36840211439a8b117 156 SUPERFAMILY SSF69118 17 145 1.73E-39 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 PRINTS PR00046 Major sigma-70 factor signature 253 265 2.4E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 PRINTS PR00046 Major sigma-70 factor signature 289 300 2.4E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 PRINTS PR00046 Major sigma-70 factor signature 105 118 2.4E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 PRINTS PR00046 Major sigma-70 factor signature 274 289 2.4E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 PRINTS PR00046 Major sigma-70 factor signature 129 137 2.4E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 SUPERFAMILY SSF88659 154 227 1.35E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 105 118 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 Gene3D G3DSA:1.10.10.10 237 314 1.2E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 78 302 3.7E-37 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 Pfam PF04545 Sigma-70, region 4 249 302 1.9E-19 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 Gene3D G3DSA:1.10.10.10 154 231 8.3E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 SUPERFAMILY SSF88659 211 309 1.42E-26 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 Gene3D G3DSA:1.10.601.10 53 153 1.7E-49 T 14-10-2018 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 Gene3D G3DSA:1.10.601.10 14 52 5.5E-7 T 14-10-2018 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 SUPERFAMILY SSF88946 16 151 1.57E-51 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 Pfam PF00140 Sigma-70 factor, region 1.2 16 49 7.2E-13 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 Pfam PF04539 Sigma-70 region 3 160 235 4.4E-24 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 Pfam PF04542 Sigma-70 region 2 81 150 4.6E-22 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_15845 47ecc1433bc87163e441fc4d50bc0324 314 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 274 300 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_01520 3fd41a2dab20f90e48f4d2a18ec7e759 379 Gene3D G3DSA:3.40.718.10 4 350 5.5E-111 T 14-10-2018 A4R43_01520 3fd41a2dab20f90e48f4d2a18ec7e759 379 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 240 259 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4R43_01520 3fd41a2dab20f90e48f4d2a18ec7e759 379 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 326 2.1E-78 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_01520 3fd41a2dab20f90e48f4d2a18ec7e759 379 SUPERFAMILY SSF53659 2 349 3.65E-100 T 14-10-2018 A4R43_01520 3fd41a2dab20f90e48f4d2a18ec7e759 379 SMART SM01329 5 346 9.7E-133 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_05260 60a3c9efc400683058944333ff21e074 316 SUPERFAMILY SSF51197 3 311 5.97E-72 T 14-10-2018 A4R43_05260 60a3c9efc400683058944333ff21e074 316 Gene3D G3DSA:2.60.120.330 1 315 2.5E-82 T 14-10-2018 IPR027443 Isopenicillin N synthase-like A4R43_05260 60a3c9efc400683058944333ff21e074 316 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 4 126 2.4E-23 T 14-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain A4R43_05260 60a3c9efc400683058944333ff21e074 316 PRINTS PR00682 Isopenicillin N synthase signature 147 163 5.7E-7 T 14-10-2018 A4R43_05260 60a3c9efc400683058944333ff21e074 316 PRINTS PR00682 Isopenicillin N synthase signature 24 41 5.7E-7 T 14-10-2018 A4R43_05260 60a3c9efc400683058944333ff21e074 316 PRINTS PR00682 Isopenicillin N synthase signature 235 261 5.7E-7 T 14-10-2018 A4R43_05260 60a3c9efc400683058944333ff21e074 316 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 179 277 7.0E-14 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 A4R43_30975 e5da176560469c9942974a69bc6d115b 156 SUPERFAMILY SSF51064 99 154 2.48E-7 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4R43_30975 e5da176560469c9942974a69bc6d115b 156 Gene3D G3DSA:2.30.22.10 97 156 3.8E-9 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4R43_30975 e5da176560469c9942974a69bc6d115b 156 Pfam PF01025 GrpE 87 153 4.3E-8 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_12345 e7d4fa975d82fdd4945750bb780198f7 245 Gene3D G3DSA:1.10.150.130 55 165 2.4E-18 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_12345 e7d4fa975d82fdd4945750bb780198f7 245 SUPERFAMILY SSF56349 61 200 6.94E-15 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_33205 592fd28dda16d4b7b03b0db9e160a4ae 250 Pfam PF14011 EspG family 12 243 8.0E-42 T 14-10-2018 IPR025734 EspG family A4R43_09145 0fe1e88673e65043d4f08b35311b4ec7 168 Gene3D G3DSA:1.10.10.10 1 166 4.1E-53 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09145 0fe1e88673e65043d4f08b35311b4ec7 168 SUPERFAMILY SSF46785 5 144 1.08E-42 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09145 0fe1e88673e65043d4f08b35311b4ec7 168 Pfam PF01638 HxlR-like helix-turn-helix 20 105 4.2E-22 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_39305 a0f21f756f192ee04495aac217e9540d 412 Pfam PF01494 FAD binding domain 301 367 8.0E-10 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_39305 a0f21f756f192ee04495aac217e9540d 412 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 59 1.2E-6 T 14-10-2018 A4R43_39305 a0f21f756f192ee04495aac217e9540d 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 2.9E-22 T 14-10-2018 A4R43_39305 a0f21f756f192ee04495aac217e9540d 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 2.9E-22 T 14-10-2018 A4R43_39305 a0f21f756f192ee04495aac217e9540d 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 2.9E-22 T 14-10-2018 A4R43_39305 a0f21f756f192ee04495aac217e9540d 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 321 2.9E-22 T 14-10-2018 A4R43_39305 a0f21f756f192ee04495aac217e9540d 412 SUPERFAMILY SSF51905 5 404 1.38E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_39305 a0f21f756f192ee04495aac217e9540d 412 Gene3D G3DSA:3.50.50.60 3 381 2.6E-111 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07120 c9925af5204794db08c98eecf3588354 339 Pfam PF00248 Aldo/keto reductase family 16 313 8.5E-71 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_07120 c9925af5204794db08c98eecf3588354 339 PRINTS PR00069 Aldo-keto reductase signature 105 123 3.2E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_07120 c9925af5204794db08c98eecf3588354 339 PRINTS PR00069 Aldo-keto reductase signature 136 153 3.2E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_07120 c9925af5204794db08c98eecf3588354 339 PRINTS PR00069 Aldo-keto reductase signature 41 65 3.2E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_07120 c9925af5204794db08c98eecf3588354 339 SUPERFAMILY SSF51430 1 314 8.77E-96 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_07120 c9925af5204794db08c98eecf3588354 339 Gene3D G3DSA:3.20.20.100 1 325 1.1E-109 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_30980 626ac1bd5c2776da08f47089932c65ec 618 Pfam PF00350 Dynamin family 54 208 5.1E-16 T 14-10-2018 IPR022812 Dynamin superfamily A4R43_30980 626ac1bd5c2776da08f47089932c65ec 618 Gene3D G3DSA:3.40.50.300 54 294 7.6E-27 T 14-10-2018 A4R43_30980 626ac1bd5c2776da08f47089932c65ec 618 SUPERFAMILY SSF52540 42 284 5.82E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33805 057441294110af22a4d46a066fb37f77 334 Gene3D G3DSA:3.20.20.150 2 323 1.1E-99 T 14-10-2018 A4R43_33805 057441294110af22a4d46a066fb37f77 334 SUPERFAMILY SSF51658 8 318 4.32E-59 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_33805 057441294110af22a4d46a066fb37f77 334 Pfam PF07582 AP endonuclease family 2 C terminus 275 329 4.4E-24 T 14-10-2018 IPR011418 AP endonuclease, family 2, C-terminal A4R43_33805 057441294110af22a4d46a066fb37f77 334 Pfam PF01261 Xylose isomerase-like TIM barrel 22 273 6.5E-35 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_34920 631ab909f342ddf61c622329c9bb2f09 409 Pfam PF05977 Transmembrane secretion effector 9 394 5.3E-22 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_34920 631ab909f342ddf61c622329c9bb2f09 409 Gene3D G3DSA:1.20.1250.20 1 392 6.2E-31 T 14-10-2018 A4R43_34920 631ab909f342ddf61c622329c9bb2f09 409 SUPERFAMILY SSF103473 5 393 3.66E-39 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18955 90aaaa7677b233649484b35a4dd88734 412 Gene3D G3DSA:1.20.1250.20 11 387 1.1E-32 T 14-10-2018 A4R43_18955 90aaaa7677b233649484b35a4dd88734 412 SUPERFAMILY SSF103473 12 400 2.88E-35 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18955 90aaaa7677b233649484b35a4dd88734 412 Pfam PF07690 Major Facilitator Superfamily 13 357 8.5E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_25995 98da04261455ce8feb71f6c5fa84ef6e 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 261 6.1E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_25995 98da04261455ce8feb71f6c5fa84ef6e 275 Gene3D G3DSA:1.10.3720.10 53 262 4.2E-55 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_25995 98da04261455ce8feb71f6c5fa84ef6e 275 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 59 155 6.3E-23 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_25995 98da04261455ce8feb71f6c5fa84ef6e 275 SUPERFAMILY SSF161098 58 261 2.09E-43 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_25310 d87453a71ff4473e1a95aa8013d73bb4 325 Pfam PF01497 Periplasmic binding protein 64 273 2.2E-17 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_25310 d87453a71ff4473e1a95aa8013d73bb4 325 Gene3D G3DSA:3.40.50.1980 164 323 2.5E-30 T 14-10-2018 A4R43_25310 d87453a71ff4473e1a95aa8013d73bb4 325 Gene3D G3DSA:3.40.50.1980 29 163 3.9E-28 T 14-10-2018 A4R43_25310 d87453a71ff4473e1a95aa8013d73bb4 325 SUPERFAMILY SSF53807 35 318 3.22E-37 T 14-10-2018 A4R43_37235 f5ca50cb1cab7a4afd8bf235595fa244 757 Gene3D G3DSA:3.30.300.30 353 433 9.9E-7 T 14-10-2018 A4R43_37235 f5ca50cb1cab7a4afd8bf235595fa244 757 Pfam PF00668 Condensation domain 462 603 1.8E-12 T 14-10-2018 IPR001242 Condensation domain A4R43_37235 f5ca50cb1cab7a4afd8bf235595fa244 757 Gene3D G3DSA:3.40.50.620 47 322 4.9E-17 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_37235 f5ca50cb1cab7a4afd8bf235595fa244 757 Pfam PF06508 Queuosine biosynthesis protein QueC 109 164 1.9E-4 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4R43_37235 f5ca50cb1cab7a4afd8bf235595fa244 757 SUPERFAMILY SSF52777 438 600 3.34E-19 T 14-10-2018 A4R43_37235 f5ca50cb1cab7a4afd8bf235595fa244 757 SUPERFAMILY SSF52402 61 290 3.53E-19 T 14-10-2018 A4R43_37235 f5ca50cb1cab7a4afd8bf235595fa244 757 Gene3D G3DSA:3.30.559.10 434 604 8.3E-29 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_38110 111a0b31dd7c292879f18a684f4205ca 539 SMART SM00642 18 415 1.7E-117 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4R43_38110 111a0b31dd7c292879f18a684f4205ca 539 Pfam PF11941 Domain of unknown function (DUF3459) 470 535 4.0E-5 T 14-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) A4R43_38110 111a0b31dd7c292879f18a684f4205ca 539 Gene3D G3DSA:3.20.20.80 10 473 7.1E-143 T 14-10-2018 A4R43_38110 111a0b31dd7c292879f18a684f4205ca 539 Gene3D G3DSA:3.90.400.10 110 187 7.1E-143 T 14-10-2018 A4R43_38110 111a0b31dd7c292879f18a684f4205ca 539 SUPERFAMILY SSF51445 8 474 2.69E-118 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_38110 111a0b31dd7c292879f18a684f4205ca 539 Pfam PF00128 Alpha amylase, catalytic domain 33 387 2.8E-75 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4R43_33480 b080959b5b4522a7e409dc004bdd91f8 318 Pfam PF00583 Acetyltransferase (GNAT) family 197 304 5.6E-8 T 14-10-2018 IPR000182 GNAT domain A4R43_33480 b080959b5b4522a7e409dc004bdd91f8 318 SUPERFAMILY SSF55729 158 311 2.34E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_33480 b080959b5b4522a7e409dc004bdd91f8 318 Gene3D G3DSA:3.40.630.30 154 307 2.0E-17 T 14-10-2018 A4R43_03610 1af6ee82e6b78df246b4cfb631dc4498 518 Gene3D G3DSA:3.10.105.10 265 462 9.4E-83 T 14-10-2018 A4R43_03610 1af6ee82e6b78df246b4cfb631dc4498 518 Gene3D G3DSA:3.40.190.10 59 264 9.4E-83 T 14-10-2018 A4R43_03610 1af6ee82e6b78df246b4cfb631dc4498 518 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 394 6.3E-65 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_03610 1af6ee82e6b78df246b4cfb631dc4498 518 SUPERFAMILY SSF53850 34 502 2.17E-91 T 14-10-2018 A4R43_03610 1af6ee82e6b78df246b4cfb631dc4498 518 PIRSF PIRSF002741 1 514 5.5E-68 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_35335 f72613dffb9e4a026e78d0a9247eb854 308 Gene3D G3DSA:1.10.620.20 1 287 4.5E-103 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4R43_35335 f72613dffb9e4a026e78d0a9247eb854 308 SUPERFAMILY SSF47240 17 289 8.12E-45 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_35335 f72613dffb9e4a026e78d0a9247eb854 308 Pfam PF00268 Ribonucleotide reductase, small chain 22 244 2.3E-13 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_35260 19f2551c2611cdd7192c6417c706a042 242 SMART SM00448 11 122 1.2E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_35260 19f2551c2611cdd7192c6417c706a042 242 SUPERFAMILY SSF52172 12 130 6.97E-40 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_35260 19f2551c2611cdd7192c6417c706a042 242 Gene3D G3DSA:3.40.50.2300 3 130 4.2E-38 T 14-10-2018 A4R43_35260 19f2551c2611cdd7192c6417c706a042 242 SMART SM00862 152 239 1.8E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_35260 19f2551c2611cdd7192c6417c706a042 242 Gene3D G3DSA:1.10.10.10 131 242 3.0E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35260 19f2551c2611cdd7192c6417c706a042 242 Pfam PF00072 Response regulator receiver domain 13 123 1.1E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_35260 19f2551c2611cdd7192c6417c706a042 242 SUPERFAMILY SSF46894 130 240 3.4E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_35260 19f2551c2611cdd7192c6417c706a042 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 239 6.8E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_29415 0cc4023a632393089043b6970f0605b5 273 Pfam PF03861 ANTAR domain 194 246 1.1E-17 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_29415 0cc4023a632393089043b6970f0605b5 273 SMART SM01012 191 246 6.7E-19 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_29415 0cc4023a632393089043b6970f0605b5 273 SUPERFAMILY SSF55781 47 191 1.61E-16 T 14-10-2018 A4R43_29415 0cc4023a632393089043b6970f0605b5 273 PIRSF PIRSF036625 6 256 2.6E-35 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4R43_29415 0cc4023a632393089043b6970f0605b5 273 Gene3D G3DSA:3.30.450.40 15 193 3.9E-17 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_29415 0cc4023a632393089043b6970f0605b5 273 SUPERFAMILY SSF52172 177 246 5.96E-8 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_29415 0cc4023a632393089043b6970f0605b5 273 Pfam PF13185 GAF domain 45 178 8.9E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_29415 0cc4023a632393089043b6970f0605b5 273 Gene3D G3DSA:1.10.10.10 194 253 2.4E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34265 5ce9915a66733afc19b2a2fed3b8b47b 216 Pfam PF00814 Glycoprotease family 36 160 9.9E-26 T 14-10-2018 IPR000905 Gcp-like domain A4R43_34265 5ce9915a66733afc19b2a2fed3b8b47b 216 SUPERFAMILY SSF53067 2 105 7.77E-20 T 14-10-2018 A4R43_34265 5ce9915a66733afc19b2a2fed3b8b47b 216 Gene3D G3DSA:3.30.420.40 3 98 3.5E-38 T 14-10-2018 A4R43_34265 5ce9915a66733afc19b2a2fed3b8b47b 216 Gene3D G3DSA:3.30.420.40 99 171 3.5E-38 T 14-10-2018 A4R43_34265 5ce9915a66733afc19b2a2fed3b8b47b 216 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 200 1.0E-50 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 A4R43_34265 5ce9915a66733afc19b2a2fed3b8b47b 216 SUPERFAMILY SSF53067 111 198 2.59E-10 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 SUPERFAMILY SSF51197 3 315 2.54E-74 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 ProSitePatterns PS00185 Isopenicillin N synthase signature 1. 93 102 - T 14-10-2018 IPR002057 Isopenicillin N synthase, conserved site GO:0005506|GO:0009058|GO:0016491|GO:0055114 KEGG: 00311+1.21.3.1|MetaCyc: PWY-5629 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 243 269 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 151 167 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 208 229 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 29 46 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 85 106 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 270 288 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 118 134 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 306 324 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 PRINTS PR00682 Isopenicillin N synthase signature 57 76 6.3E-103 T 14-10-2018 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 181 281 8.2E-15 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 A4R43_03225 845d211b79858ac37f3c256a93d12128 325 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 6 128 8.6E-16 T 14-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain A4R43_03225 845d211b79858ac37f3c256a93d12128 325 Gene3D G3DSA:2.60.120.330 1 325 1.4E-103 T 14-10-2018 IPR027443 Isopenicillin N synthase-like A4R43_31015 bee77390a1f48545df1de319ba56f52b 88 Pfam PF13560 Helix-turn-helix domain 16 76 7.8E-11 T 14-10-2018 A4R43_31015 bee77390a1f48545df1de319ba56f52b 88 SMART SM00530 20 74 5.8E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_31015 bee77390a1f48545df1de319ba56f52b 88 Gene3D G3DSA:1.10.260.40 7 75 8.5E-30 T 14-10-2018 A4R43_31015 bee77390a1f48545df1de319ba56f52b 88 SUPERFAMILY SSF47413 10 81 5.04E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 345 359 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Gene3D G3DSA:1.10.460.10 178 618 1.5E-176 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Gene3D G3DSA:1.10.290.10 316 444 1.5E-176 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 SUPERFAMILY SSF56712 33 619 2.88E-176 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 SMART SM00436 147 235 1.4E-42 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Pfam PF13368 Topoisomerase C-terminal repeat 720 794 4.8E-13 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Pfam PF13368 Topoisomerase C-terminal repeat 866 918 2.0E-19 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Pfam PF13368 Topoisomerase C-terminal repeat 799 852 4.6E-17 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Pfam PF13368 Topoisomerase C-terminal repeat 662 714 1.1E-8 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 35 690 1.0E-248 T 14-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 429 445 4.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 205 223 4.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 350 359 4.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 121 134 4.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 541 555 4.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Gene3D G3DSA:2.70.20.10 227 525 1.5E-176 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Pfam PF01131 DNA topoisomerase 171 615 3.3E-120 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 SMART SM00493 33 147 1.5E-35 T 14-10-2018 IPR006171 TOPRIM domain A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Gene3D G3DSA:3.40.50.140 32 177 6.2E-56 T 14-10-2018 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 SMART SM00437 308 578 7.5E-118 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Pfam PF01751 Toprim domain 35 156 4.8E-28 T 14-10-2018 IPR006171 TOPRIM domain A4R43_26965 5f69ed931b301f3a4ae1d53d60db1c81 942 Hamap MF_00952 DNA topoisomerase 1 [topA]. 33 820 55.127 T 14-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A4R43_13585 b63741c4458726eedee4b320e6456913 408 SUPERFAMILY SSF53474 4 404 2.86E-75 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13585 b63741c4458726eedee4b320e6456913 408 PRINTS PR00412 Epoxide hydrolase signature 131 146 1.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_13585 b63741c4458726eedee4b320e6456913 408 PRINTS PR00412 Epoxide hydrolase signature 380 402 1.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_13585 b63741c4458726eedee4b320e6456913 408 PRINTS PR00412 Epoxide hydrolase signature 102 120 1.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_13585 b63741c4458726eedee4b320e6456913 408 PIRSF PIRSF001112 2 407 7.0E-87 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_13585 b63741c4458726eedee4b320e6456913 408 Pfam PF06441 Epoxide hydrolase N terminus 8 110 7.7E-29 T 14-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 A4R43_13585 b63741c4458726eedee4b320e6456913 408 Gene3D G3DSA:3.40.50.1820 4 406 5.2E-108 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_39380 3fd0b5f2105ac071064bbaf2b64286ea 325 Pfam PF06144 DNA polymerase III, delta subunit 11 174 6.3E-9 T 14-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 A4R43_39380 3fd0b5f2105ac071064bbaf2b64286ea 325 Gene3D G3DSA:1.20.272.10 200 324 2.9E-15 T 14-10-2018 A4R43_39380 3fd0b5f2105ac071064bbaf2b64286ea 325 SUPERFAMILY SSF48019 202 320 1.02E-12 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4R43_39380 3fd0b5f2105ac071064bbaf2b64286ea 325 Gene3D G3DSA:3.40.50.300 5 127 8.0E-13 T 14-10-2018 A4R43_39380 3fd0b5f2105ac071064bbaf2b64286ea 325 SUPERFAMILY SSF52540 11 184 3.11E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_07125 014701250868293eeb200b5ecc4e1dc4 289 SUPERFAMILY SSF51679 9 272 2.62E-54 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_07125 014701250868293eeb200b5ecc4e1dc4 289 Gene3D G3DSA:3.20.20.30 2 288 5.6E-60 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_07125 014701250868293eeb200b5ecc4e1dc4 289 Pfam PF00296 Luciferase-like monooxygenase 11 254 1.7E-41 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 SUPERFAMILY SSF48264 12 403 2.49E-89 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 Pfam PF00067 Cytochrome P450 39 370 3.2E-33 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 Gene3D G3DSA:1.10.630.10 2 404 1.2E-113 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 PRINTS PR00359 B-class P450 signature 142 157 9.0E-38 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 PRINTS PR00359 B-class P450 signature 186 208 9.0E-38 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 PRINTS PR00359 B-class P450 signature 352 363 9.0E-38 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 PRINTS PR00359 B-class P450 signature 125 141 9.0E-38 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 PRINTS PR00359 B-class P450 signature 284 311 9.0E-38 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 PRINTS PR00359 B-class P450 signature 343 352 9.0E-38 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 PRINTS PR00359 B-class P450 signature 267 278 9.0E-38 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06685 883b243ed6c03ff9e767332c46db85df 405 PRINTS PR00359 B-class P450 signature 312 327 9.0E-38 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_06915 10f31eab66eb855479a2dceac610c5e1 338 SUPERFAMILY SSF54631 210 329 7.71E-19 T 14-10-2018 A4R43_06915 10f31eab66eb855479a2dceac610c5e1 338 Pfam PF00571 CBS domain 279 330 1.2E-4 T 14-10-2018 IPR000644 CBS domain A4R43_06915 10f31eab66eb855479a2dceac610c5e1 338 Pfam PF00571 CBS domain 225 272 0.0025 T 14-10-2018 IPR000644 CBS domain A4R43_06915 10f31eab66eb855479a2dceac610c5e1 338 Gene3D G3DSA:3.90.1280.20 227 285 3.8E-20 T 14-10-2018 A4R43_06915 10f31eab66eb855479a2dceac610c5e1 338 Pfam PF01595 Domain of unknown function DUF21 11 200 1.1E-41 T 14-10-2018 IPR002550 CNNM, transmembrane domain A4R43_06915 10f31eab66eb855479a2dceac610c5e1 338 SMART SM00116 283 330 0.16 T 14-10-2018 IPR000644 CBS domain A4R43_06915 10f31eab66eb855479a2dceac610c5e1 338 SMART SM00116 228 275 5.4 T 14-10-2018 IPR000644 CBS domain A4R43_06915 10f31eab66eb855479a2dceac610c5e1 338 Gene3D G3DSA:3.10.580.10 189 326 3.8E-20 T 14-10-2018 A4R43_02995 cecee5313ed4016f75de0546f8553f45 93 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 8.4E-45 T 14-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 A4R43_02995 cecee5313ed4016f75de0546f8553f45 93 Pfam PF02426 Muconolactone delta-isomerase 1 89 5.4E-40 T 14-10-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 A4R43_02995 cecee5313ed4016f75de0546f8553f45 93 Gene3D G3DSA:3.30.70.1060 1 93 4.5E-37 T 14-10-2018 A4R43_02995 cecee5313ed4016f75de0546f8553f45 93 SUPERFAMILY SSF54909 1 91 7.24E-37 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_02995 cecee5313ed4016f75de0546f8553f45 93 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 2.0E-23 T 14-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 A4R43_02995 cecee5313ed4016f75de0546f8553f45 93 PIRSF PIRSF001486 1 93 2.6E-43 T 14-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 A4R43_05195 0670e8fa6d1aa937b5afb8ce0c7738ee 282 SUPERFAMILY SSF52096 6 265 2.57E-76 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_05195 0670e8fa6d1aa937b5afb8ce0c7738ee 282 Gene3D G3DSA:3.90.226.10 2 207 3.8E-68 T 14-10-2018 A4R43_05195 0670e8fa6d1aa937b5afb8ce0c7738ee 282 Gene3D G3DSA:1.10.12.10 209 267 1.5E-7 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_05195 0670e8fa6d1aa937b5afb8ce0c7738ee 282 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 265 3.1E-49 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_05195 0670e8fa6d1aa937b5afb8ce0c7738ee 282 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_27650 68d0680974540238ddc828a6b5228596 160 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 9 155 3.1E-52 T 14-10-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative A4R43_38035 dd933d68b51ef5fd1e887231148f66eb 288 Pfam PF13354 Beta-lactamase enzyme family 22 250 2.4E-52 T 14-10-2018 A4R43_38035 dd933d68b51ef5fd1e887231148f66eb 288 SUPERFAMILY SSF56601 15 271 1.03E-37 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_38035 dd933d68b51ef5fd1e887231148f66eb 288 Gene3D G3DSA:3.40.710.10 1 287 1.9E-68 T 14-10-2018 A4R43_34870 38235313c549dbf8326807568e2560b3 226 SUPERFAMILY SSF52200 3 107 9.16E-11 T 14-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily A4R43_34870 38235313c549dbf8326807568e2560b3 226 Gene3D G3DSA:3.40.50.10140 2 147 3.2E-15 T 14-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily A4R43_34870 38235313c549dbf8326807568e2560b3 226 Pfam PF13676 TIR domain 4 127 1.6E-16 T 14-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 A4R43_41030 575a99596a4c721040e0e33e3206f347 341 Gene3D G3DSA:3.90.1150.10 15 331 8.2E-41 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_41030 575a99596a4c721040e0e33e3206f347 341 SUPERFAMILY SSF53383 15 338 4.15E-37 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_41030 575a99596a4c721040e0e33e3206f347 341 Gene3D G3DSA:3.40.640.10 25 265 8.2E-41 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_41030 575a99596a4c721040e0e33e3206f347 341 Pfam PF00266 Aminotransferase class-V 48 281 6.7E-10 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_38570 7592666b7036bedf1712909fd37445d4 322 Pfam PF00296 Luciferase-like monooxygenase 1 290 7.2E-45 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_38570 7592666b7036bedf1712909fd37445d4 322 Gene3D G3DSA:3.20.20.30 1 319 5.1E-56 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_38570 7592666b7036bedf1712909fd37445d4 322 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 3 319 1.0E-145 T 14-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related A4R43_38570 7592666b7036bedf1712909fd37445d4 322 SUPERFAMILY SSF51679 1 318 2.36E-55 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_28530 0acc57926d7a2712c446f5e0dbb0bbb7 199 Pfam PF01169 Uncharacterized protein family UPF0016 116 189 1.8E-19 T 14-10-2018 IPR001727 Gdt1 family A4R43_28530 0acc57926d7a2712c446f5e0dbb0bbb7 199 Pfam PF01169 Uncharacterized protein family UPF0016 10 79 3.2E-14 T 14-10-2018 IPR001727 Gdt1 family A4R43_38945 10301a450c3cdb8ce5fc96f3acfa8c7a 105 Pfam PF13601 Winged helix DNA-binding domain 20 95 9.3E-23 T 14-10-2018 IPR027395 Winged helix DNA-binding domain A4R43_38945 10301a450c3cdb8ce5fc96f3acfa8c7a 105 SUPERFAMILY SSF46785 19 94 3.04E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38945 10301a450c3cdb8ce5fc96f3acfa8c7a 105 Gene3D G3DSA:1.10.10.10 1 97 1.2E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37230 aa90c7779da8e5b420fbe3d6e90dfbeb 227 Pfam PF01177 Asp/Glu/Hydantoin racemase 1 212 1.7E-45 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_37230 aa90c7779da8e5b420fbe3d6e90dfbeb 227 SUPERFAMILY SSF53681 1 101 9.81E-23 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_37230 aa90c7779da8e5b420fbe3d6e90dfbeb 227 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 192 3.1E-37 T 14-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A4R43_37230 aa90c7779da8e5b420fbe3d6e90dfbeb 227 SUPERFAMILY SSF53681 94 193 4.74E-14 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_37230 aa90c7779da8e5b420fbe3d6e90dfbeb 227 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_37230 aa90c7779da8e5b420fbe3d6e90dfbeb 227 Gene3D G3DSA:3.40.50.1860 96 204 1.1E-53 T 14-10-2018 A4R43_37230 aa90c7779da8e5b420fbe3d6e90dfbeb 227 Gene3D G3DSA:3.40.50.1860 1 209 1.1E-53 T 14-10-2018 A4R43_17200 9e1b3825d7ed1512af94e0f1b0958eea 243 SUPERFAMILY SSF53335 39 220 1.32E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_17200 9e1b3825d7ed1512af94e0f1b0958eea 243 Pfam PF05175 Methyltransferase small domain 65 200 1.2E-5 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A4R43_17200 9e1b3825d7ed1512af94e0f1b0958eea 243 Gene3D G3DSA:3.40.50.150 32 215 5.2E-16 T 14-10-2018 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 SUPERFAMILY SSF53706 4 566 3.53E-122 T 14-10-2018 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 Gene3D G3DSA:2.40.40.20 575 715 2.3E-27 T 14-10-2018 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 Gene3D G3DSA:3.40.228.10 131 330 3.3E-100 T 14-10-2018 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 Pfam PF00384 Molybdopterin oxidoreductase 56 438 4.0E-43 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 Gene3D G3DSA:2.20.25.90 1 58 9.1E-14 T 14-10-2018 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 Gene3D G3DSA:3.40.50.740 63 475 3.3E-100 T 14-10-2018 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 SMART SM00926 1 53 4.1E-9 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 49 4.7E-10 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 SUPERFAMILY SSF50692 585 715 2.94E-31 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4R43_31465 2444dc0b63212611aaba55bbbb15e03f 715 Pfam PF01568 Molydopterin dinucleotide binding domain 589 706 1.5E-22 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 Gene3D G3DSA:3.40.47.10 125 370 6.9E-130 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 ProSitePatterns PS00737 Thiolases signature 2. 322 338 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 PIRSF PIRSF000429 1 376 1.6E-115 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 SUPERFAMILY SSF53901 254 375 1.3E-38 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 374 2.1E-116 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 Gene3D G3DSA:3.40.47.10 6 259 6.9E-130 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 SUPERFAMILY SSF53901 4 253 3.39E-64 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 Pfam PF00108 Thiolase, N-terminal domain 5 245 2.8E-60 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_15930 1b74f3d7e465e5550a8a554529b991e2 376 Pfam PF02803 Thiolase, C-terminal domain 254 375 7.3E-39 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_32895 adad7b919defb1e44eba6ecb5b14bf5b 107 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 7 101 1.2E-6 T 14-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 A4R43_39630 cf615689b74496946fed3d8847d4ee65 498 Gene3D G3DSA:3.40.605.10 24 459 3.0E-153 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_39630 cf615689b74496946fed3d8847d4ee65 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_39630 cf615689b74496946fed3d8847d4ee65 498 Pfam PF00171 Aldehyde dehydrogenase family 21 478 1.6E-144 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_39630 cf615689b74496946fed3d8847d4ee65 498 Gene3D G3DSA:3.40.309.10 250 451 3.0E-153 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_39630 cf615689b74496946fed3d8847d4ee65 498 SUPERFAMILY SSF53720 3 484 6.15E-150 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_39630 cf615689b74496946fed3d8847d4ee65 498 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 482 2.4E-217 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 A4R43_04350 edc0a7d896b712e847907c50490dbe2b 172 Pfam PF00156 Phosphoribosyl transferase domain 35 148 9.2E-7 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4R43_04350 edc0a7d896b712e847907c50490dbe2b 172 SUPERFAMILY SSF53271 13 166 2.35E-38 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_04350 edc0a7d896b712e847907c50490dbe2b 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 6 172 29.016 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A4R43_04350 edc0a7d896b712e847907c50490dbe2b 172 Gene3D G3DSA:3.40.50.2020 5 171 1.2E-48 T 14-10-2018 A4R43_29335 a25dc3cfc632afcc9b25132742de187c 98 Gene3D G3DSA:3.40.30.10 16 96 7.8E-15 T 14-10-2018 A4R43_29335 a25dc3cfc632afcc9b25132742de187c 98 SUPERFAMILY SSF52833 10 80 1.06E-13 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_29335 a25dc3cfc632afcc9b25132742de187c 98 Pfam PF00462 Glutaredoxin 20 78 2.7E-12 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A4R43_20440 65435461781a3c9a63100cc04daca63b 246 Pfam PF00491 Arginase family 42 203 8.2E-25 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_20440 65435461781a3c9a63100cc04daca63b 246 PRINTS PR00116 Arginase signature 81 108 8.5E-7 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_20440 65435461781a3c9a63100cc04daca63b 246 PRINTS PR00116 Arginase signature 58 73 8.5E-7 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_20440 65435461781a3c9a63100cc04daca63b 246 PIRSF PIRSF036979 5 205 6.2E-15 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_20440 65435461781a3c9a63100cc04daca63b 246 SUPERFAMILY SSF52768 31 224 3.42E-36 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily A4R43_20440 65435461781a3c9a63100cc04daca63b 246 Gene3D G3DSA:3.40.800.10 11 214 2.1E-37 T 14-10-2018 A4R43_00415 8ab1890fc77808d7815f5ea20a2cacaa 173 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 17 161 1.6E-17 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 A4R43_17115 b398b851396f12d8292cb5e4156da29f 417 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 2 415 7.7E-103 T 14-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_17115 b398b851396f12d8292cb5e4156da29f 417 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 14 225 1.2E-35 T 14-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_17115 b398b851396f12d8292cb5e4156da29f 417 SUPERFAMILY SSF52777 3 140 3.78E-11 T 14-10-2018 A4R43_17115 b398b851396f12d8292cb5e4156da29f 417 Pfam PF06974 Protein of unknown function (DUF1298) 267 410 1.7E-25 T 14-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_17115 b398b851396f12d8292cb5e4156da29f 417 Gene3D G3DSA:3.30.559.10 1 172 4.5E-8 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_07750 ee4a3db39d61c57d09ccd359190649d7 144 Pfam PF00102 Protein-tyrosine phosphatase 51 109 1.1E-5 T 14-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 A4R43_07750 ee4a3db39d61c57d09ccd359190649d7 144 Gene3D G3DSA:3.90.190.10 32 143 3.3E-21 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like A4R43_07750 ee4a3db39d61c57d09ccd359190649d7 144 SUPERFAMILY SSF52799 47 141 8.84E-22 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like A4R43_34715 6abbde9a38e182ff15c1c3d44fbb77af 533 Gene3D G3DSA:3.40.50.720 2 94 6.1E-12 T 14-10-2018 A4R43_34715 6abbde9a38e182ff15c1c3d44fbb77af 533 Pfam PF12831 FAD dependent oxidoreductase 8 507 4.7E-110 T 14-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal A4R43_34715 6abbde9a38e182ff15c1c3d44fbb77af 533 SUPERFAMILY SSF51905 5 264 1.74E-19 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38580 8d9c85218f02c2318d36072f248f2728 316 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 14-10-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 A4R43_38580 8d9c85218f02c2318d36072f248f2728 316 Gene3D G3DSA:3.90.245.10 1 316 5.1E-92 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like A4R43_38580 8d9c85218f02c2318d36072f248f2728 316 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 305 8.1E-76 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A4R43_38580 8d9c85218f02c2318d36072f248f2728 316 SUPERFAMILY SSF53590 3 314 3.01E-80 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like A4R43_31815 2d0f3777300c4633ab8d6a3aae4ca2e5 211 Pfam PF13483 Beta-lactamase superfamily domain 6 176 1.9E-19 T 14-10-2018 A4R43_31815 2d0f3777300c4633ab8d6a3aae4ca2e5 211 SMART SM00849 7 176 3.3E-8 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_31815 2d0f3777300c4633ab8d6a3aae4ca2e5 211 Gene3D G3DSA:3.60.15.10 1 187 5.1E-35 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_31815 2d0f3777300c4633ab8d6a3aae4ca2e5 211 SUPERFAMILY SSF56281 1 195 6.42E-27 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_34580 fb84e7f80b93ddba9432aab3b9f59884 214 Gene3D G3DSA:3.40.50.150 41 213 1.4E-31 T 14-10-2018 A4R43_34580 fb84e7f80b93ddba9432aab3b9f59884 214 Pfam PF01564 Spermine/spermidine synthase domain 46 174 4.9E-7 T 14-10-2018 A4R43_34580 fb84e7f80b93ddba9432aab3b9f59884 214 SUPERFAMILY SSF53335 14 204 1.51E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_34790 ed895d0abec8dd8f6f0bef40027eaba1 394 Pfam PF07690 Major Facilitator Superfamily 19 357 6.6E-43 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_34790 ed895d0abec8dd8f6f0bef40027eaba1 394 Gene3D G3DSA:1.20.1250.20 5 197 5.3E-31 T 14-10-2018 A4R43_34790 ed895d0abec8dd8f6f0bef40027eaba1 394 SUPERFAMILY SSF103473 6 388 2.35E-60 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_34790 ed895d0abec8dd8f6f0bef40027eaba1 394 Gene3D G3DSA:1.20.1250.20 209 393 6.1E-24 T 14-10-2018 A4R43_05090 03d699f993cf0407e4993b78cf345567 409 SUPERFAMILY SSF55874 296 404 9.46E-5 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_05090 03d699f993cf0407e4993b78cf345567 409 Gene3D G3DSA:3.30.565.10 285 405 1.7E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_05090 03d699f993cf0407e4993b78cf345567 409 Pfam PF07730 Histidine kinase 210 275 2.5E-17 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_02165 62d8d84ab42071667890adef3e646b38 236 SUPERFAMILY SSF64288 61 232 2.09E-28 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_02165 62d8d84ab42071667890adef3e646b38 236 SMART SM00345 14 73 1.3E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02165 62d8d84ab42071667890adef3e646b38 236 Gene3D G3DSA:1.10.10.10 4 76 4.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02165 62d8d84ab42071667890adef3e646b38 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 1.9E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02165 62d8d84ab42071667890adef3e646b38 236 SMART SM00866 88 228 4.1E-16 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_02165 62d8d84ab42071667890adef3e646b38 236 SUPERFAMILY SSF46785 3 86 2.54E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02165 62d8d84ab42071667890adef3e646b38 236 Pfam PF07702 UTRA domain 92 228 2.6E-19 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_02165 62d8d84ab42071667890adef3e646b38 236 Gene3D G3DSA:3.40.1410.10 77 231 4.7E-33 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_31480 5a64cd23cbdfb7c2769f1975b339fff8 296 SUPERFAMILY SSF53822 19 288 9.62E-59 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_31480 5a64cd23cbdfb7c2769f1975b339fff8 296 Gene3D G3DSA:3.40.50.2300 116 247 5.5E-61 T 14-10-2018 A4R43_31480 5a64cd23cbdfb7c2769f1975b339fff8 296 Gene3D G3DSA:3.40.50.2300 28 264 5.5E-61 T 14-10-2018 A4R43_31480 5a64cd23cbdfb7c2769f1975b339fff8 296 Pfam PF13377 Periplasmic binding protein-like domain 125 286 1.0E-31 T 14-10-2018 A4R43_15185 d234308198d3d02816e66eff1bbb9634 202 Gene3D G3DSA:1.10.357.10 1 185 4.6E-48 T 14-10-2018 A4R43_15185 d234308198d3d02816e66eff1bbb9634 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15185 d234308198d3d02816e66eff1bbb9634 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15185 d234308198d3d02816e66eff1bbb9634 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 7.7E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15185 d234308198d3d02816e66eff1bbb9634 202 SUPERFAMILY SSF46689 1 73 3.74E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_15185 d234308198d3d02816e66eff1bbb9634 202 SUPERFAMILY SSF48498 76 180 7.57E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_39200 e3fa5a928b2d1b9f531b2dcaa7794ad2 513 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 44 134 9.0E-22 T 14-10-2018 IPR032093 Phospholipase D, N-terminal A4R43_39200 e3fa5a928b2d1b9f531b2dcaa7794ad2 513 Pfam PF09423 PhoD-like phosphatase 152 494 1.5E-77 T 14-10-2018 IPR018946 Alkaline phosphatase D-related A4R43_39200 e3fa5a928b2d1b9f531b2dcaa7794ad2 513 Gene3D G3DSA:3.60.21.70 158 471 3.4E-62 T 14-10-2018 IPR038607 PhoD-like superfamily A4R43_39200 e3fa5a928b2d1b9f531b2dcaa7794ad2 513 Gene3D G3DSA:2.60.40.380 37 137 5.3E-10 T 14-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 A4R43_39200 e3fa5a928b2d1b9f531b2dcaa7794ad2 513 SUPERFAMILY SSF56300 139 509 1.37E-36 T 14-10-2018 A4R43_10180 53bbdbb5c27c28fd94d0ca56dc83d18f 167 Gene3D G3DSA:3.40.630.30 1 142 3.1E-25 T 14-10-2018 A4R43_10180 53bbdbb5c27c28fd94d0ca56dc83d18f 167 Pfam PF00583 Acetyltransferase (GNAT) family 29 130 5.1E-15 T 14-10-2018 IPR000182 GNAT domain A4R43_10180 53bbdbb5c27c28fd94d0ca56dc83d18f 167 SUPERFAMILY SSF55729 1 134 1.7E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_17700 03f96f47d2a3dbc8f5f5818007b8e22a 208 Pfam PF00510 Cytochrome c oxidase subunit III 17 206 6.3E-28 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_17700 03f96f47d2a3dbc8f5f5818007b8e22a 208 Gene3D G3DSA:1.20.120.80 18 208 8.3E-54 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_17700 03f96f47d2a3dbc8f5f5818007b8e22a 208 SUPERFAMILY SSF81452 10 206 2.49E-56 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_15110 ecbf2d835c120a8f8de533ef36c6e597 106 SUPERFAMILY SSF46955 38 88 8.79E-6 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_15110 ecbf2d835c120a8f8de533ef36c6e597 106 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 38 82 5.3E-8 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A4R43_15110 ecbf2d835c120a8f8de533ef36c6e597 106 Pfam PF12728 Helix-turn-helix domain 38 86 1.1E-10 T 14-10-2018 A4R43_30960 843d86ad2ec94ac510064bb166e689b7 527 Gene3D G3DSA:3.40.50.300 51 310 6.3E-24 T 14-10-2018 A4R43_30960 843d86ad2ec94ac510064bb166e689b7 527 SUPERFAMILY SSF52540 46 245 1.53E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30960 843d86ad2ec94ac510064bb166e689b7 527 Pfam PF00350 Dynamin family 51 204 7.0E-12 T 14-10-2018 IPR022812 Dynamin superfamily A4R43_27670 722b8ddadeff6442e5ca47ce49b10656 649 Pfam PF13515 Fusaric acid resistance protein-like 348 469 1.2E-20 T 14-10-2018 A4R43_27670 722b8ddadeff6442e5ca47ce49b10656 649 Pfam PF12805 FUSC-like inner membrane protein yccS 89 235 4.8E-5 T 14-10-2018 IPR032692 Integral membrane protein YccS, N-terminal A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 Hamap MF_01685 Ferredoxin--NADP reductase. 7 327 38.949 T 14-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 293 1.9E-30 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 SUPERFAMILY SSF51905 5 310 2.14E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 3.9E-15 T 14-10-2018 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.9E-15 T 14-10-2018 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 3.9E-15 T 14-10-2018 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 9.6E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 274 292 9.6E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 9.6E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 9.6E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 9.6E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 201 217 9.6E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 Gene3D G3DSA:3.50.50.60 128 245 4.9E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23520 5e034ffe711c742e79a9ec8dc2f0acd6 328 Gene3D G3DSA:3.50.50.60 9 306 4.9E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_09050 baa38751cb794c88f03f86bf67d9b571 321 SUPERFAMILY SSF51430 1 308 2.88E-87 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_09050 baa38751cb794c88f03f86bf67d9b571 321 Pfam PF00248 Aldo/keto reductase family 15 305 4.3E-63 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_09050 baa38751cb794c88f03f86bf67d9b571 321 Gene3D G3DSA:3.20.20.100 1 320 4.7E-101 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 Pfam PF01037 Lrp/AsnC ligand binding domain 75 147 4.8E-13 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 1.2E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 SMART SM00344 7 116 7.9E-31 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 Gene3D G3DSA:1.10.10.10 1 60 1.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.6E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.6E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.6E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 SUPERFAMILY SSF54909 69 149 3.49E-14 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 Gene3D G3DSA:3.30.70.920 61 143 3.4E-20 T 14-10-2018 A4R43_40890 f6858164477af6c2f4428c3ab8903889 163 SUPERFAMILY SSF46785 6 66 8.85E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_17890 6e5598bbbdb5ef5506a6c08aaad77347 224 Pfam PF09335 SNARE associated Golgi protein 40 163 1.2E-18 T 14-10-2018 IPR032816 SNARE associated Golgi protein A4R43_00160 1acb05221bc1b6660960d0b34dfde93a 414 SUPERFAMILY SSF88659 96 156 8.18E-7 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_00160 1acb05221bc1b6660960d0b34dfde93a 414 Gene3D G3DSA:1.10.1740.10 2 74 1.9E-6 T 14-10-2018 A4R43_00160 1acb05221bc1b6660960d0b34dfde93a 414 SUPERFAMILY SSF88946 8 93 2.39E-10 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_00160 1acb05221bc1b6660960d0b34dfde93a 414 Pfam PF08281 Sigma-70, region 4 105 155 3.9E-6 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_00160 1acb05221bc1b6660960d0b34dfde93a 414 Pfam PF04542 Sigma-70 region 2 22 77 5.1E-7 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_17835 73d8a7c1b8a143cf6b4fc0d98fd1a09d 118 Gene3D G3DSA:3.10.450.50 5 113 4.3E-9 T 14-10-2018 A4R43_17835 73d8a7c1b8a143cf6b4fc0d98fd1a09d 118 SUPERFAMILY SSF54427 16 106 8.78E-10 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 Pfam PF07729 FCD domain 81 201 3.3E-27 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 SUPERFAMILY SSF46785 3 67 6.25E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 53 6.6E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 23 37 6.6E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 SUPERFAMILY SSF48008 79 208 8.63E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 SMART SM00895 81 202 5.6E-24 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 SMART SM00345 4 63 9.0E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 63 1.6E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 Gene3D G3DSA:1.10.10.10 1 66 3.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17935 776d1dedc197428c0078eb4c0d6ac318 222 Gene3D G3DSA:1.20.120.530 78 216 2.7E-31 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_38925 2296eb42a14ccc4486b31d278c04652a 181 SUPERFAMILY SSF54001 59 172 9.32E-37 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_38925 2296eb42a14ccc4486b31d278c04652a 181 Gene3D G3DSA:3.90.1720.10 9 178 3.1E-43 T 14-10-2018 A4R43_38925 2296eb42a14ccc4486b31d278c04652a 181 Pfam PF00877 NlpC/P60 family 79 166 2.2E-23 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_07435 b6b1a680b9fe2625429a1dbd740883db 281 Pfam PF05368 NmrA-like family 3 213 1.2E-23 T 14-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 A4R43_07435 b6b1a680b9fe2625429a1dbd740883db 281 SUPERFAMILY SSF51735 3 249 2.81E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07435 b6b1a680b9fe2625429a1dbd740883db 281 Gene3D G3DSA:3.90.25.10 132 262 1.5E-72 T 14-10-2018 A4R43_07435 b6b1a680b9fe2625429a1dbd740883db 281 Gene3D G3DSA:3.40.50.720 4 260 1.5E-72 T 14-10-2018 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 380 1.8E-40 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 Gene3D G3DSA:1.20.140.10 238 381 1.5E-43 T 14-10-2018 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 SUPERFAMILY SSF47203 232 381 1.14E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 SUPERFAMILY SSF56645 7 245 4.97E-84 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 PIRSF PIRSF016578 3 381 3.2E-13 T 14-10-2018 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 Gene3D G3DSA:1.10.540.10 3 123 3.5E-36 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 121 8.9E-33 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 Gene3D G3DSA:2.40.110.10 124 237 4.6E-41 T 14-10-2018 A4R43_30210 252bb60d97921fa7af0c925475fa2f79 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 220 1.4E-27 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_18030 28aae72e469da58344413e4f7127a366 936 SUPERFAMILY SSF52518 509 741 4.36E-86 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_18030 28aae72e469da58344413e4f7127a366 936 SUPERFAMILY SSF52922 744 922 7.85E-50 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_18030 28aae72e469da58344413e4f7127a366 936 Gene3D G3DSA:3.40.50.920 749 929 3.1E-60 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_18030 28aae72e469da58344413e4f7127a366 936 Gene3D G3DSA:3.40.50.970 506 746 1.8E-102 T 14-10-2018 A4R43_18030 28aae72e469da58344413e4f7127a366 936 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 34 926 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4R43_18030 28aae72e469da58344413e4f7127a366 936 SUPERFAMILY SSF52518 84 502 7.63E-132 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_18030 28aae72e469da58344413e4f7127a366 936 Gene3D G3DSA:3.40.50.970 83 505 4.3E-132 T 14-10-2018 A4R43_18030 28aae72e469da58344413e4f7127a366 936 PIRSF PIRSF000156 24 930 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4R43_18030 28aae72e469da58344413e4f7127a366 936 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 165 328 1.1E-8 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_14600 89deb3159a3b9dab1d4c2e1aefb3a4a3 291 SUPERFAMILY SSF48239 23 262 3.73E-6 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4R43_13960 c6a32a3a784c0d92d15166a3a953ec6d 297 Pfam PF13612 Transposase DDE domain 106 254 1.2E-15 T 14-10-2018 IPR025668 Transposase DDE domain A4R43_16755 c6a32a3a784c0d92d15166a3a953ec6d 297 Pfam PF13612 Transposase DDE domain 106 254 1.2E-15 T 14-10-2018 IPR025668 Transposase DDE domain A4R43_28055 c6a32a3a784c0d92d15166a3a953ec6d 297 Pfam PF13612 Transposase DDE domain 106 254 1.2E-15 T 14-10-2018 IPR025668 Transposase DDE domain A4R43_26705 104177975d4bde23454bd24bac32981f 475 SUPERFAMILY SSF63737 42 234 4.71E-35 T 14-10-2018 A4R43_26705 104177975d4bde23454bd24bac32981f 475 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 172 187 4.7E-7 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_26705 104177975d4bde23454bd24bac32981f 475 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 335 347 4.7E-7 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_26705 104177975d4bde23454bd24bac32981f 475 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 219 234 4.7E-7 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_26705 104177975d4bde23454bd24bac32981f 475 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 316 331 4.7E-7 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_26705 104177975d4bde23454bd24bac32981f 475 Gene3D G3DSA:2.60.40.1730 54 237 3.2E-26 T 14-10-2018 A4R43_26705 104177975d4bde23454bd24bac32981f 475 SUPERFAMILY SSF55486 264 463 8.06E-37 T 14-10-2018 A4R43_26705 104177975d4bde23454bd24bac32981f 475 Gene3D G3DSA:1.10.390.60 257 460 3.6E-26 T 14-10-2018 A4R43_26705 104177975d4bde23454bd24bac32981f 475 Pfam PF01433 Peptidase family M1 domain 315 456 3.2E-19 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_15420 7e1ba56079290554bcb84b1db0a15180 128 SUPERFAMILY SSF54427 3 112 1.71E-28 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_15420 7e1ba56079290554bcb84b1db0a15180 128 Gene3D G3DSA:3.10.450.50 1 113 1.3E-38 T 14-10-2018 A4R43_15420 7e1ba56079290554bcb84b1db0a15180 128 Pfam PF12680 SnoaL-like domain 3 97 1.8E-15 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_20660 c4d2d7e5f8f90d548304ad5b88ce0346 504 Gene3D G3DSA:3.40.50.300 20 108 1.4E-12 T 14-10-2018 A4R43_20660 c4d2d7e5f8f90d548304ad5b88ce0346 504 Gene3D G3DSA:3.40.50.300 214 403 1.9E-22 T 14-10-2018 A4R43_20660 c4d2d7e5f8f90d548304ad5b88ce0346 504 Pfam PF05872 Bacterial protein of unknown function (DUF853) 33 501 5.0E-193 T 14-10-2018 IPR033186 Helicase HerA-like C-terminal A4R43_20660 c4d2d7e5f8f90d548304ad5b88ce0346 504 SUPERFAMILY SSF52540 24 390 1.07E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 Gene3D G3DSA:3.40.50.80 110 248 3.5E-31 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 PRINTS PR00410 Phenol hydroxylase reductase family signature 60 67 3.9E-6 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 PRINTS PR00410 Phenol hydroxylase reductase family signature 118 137 3.9E-6 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 221 3.9E-6 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 Pfam PF00970 Oxidoreductase FAD-binding domain 12 107 9.6E-8 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 SUPERFAMILY SSF54292 235 353 2.23E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 Gene3D G3DSA:2.40.30.10 3 105 1.3E-17 T 14-10-2018 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 SUPERFAMILY SSF52343 97 243 1.83E-34 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 9 355 1.0E-152 T 14-10-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 SUPERFAMILY SSF63380 6 109 1.34E-20 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 273 345 6.6E-14 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 60 67 3.8E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 142 151 3.8E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 154 165 3.8E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 118 137 3.8E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 Gene3D G3DSA:3.10.20.30 257 356 1.6E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 Pfam PF00175 Oxidoreductase NAD-binding domain 119 227 3.5E-18 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_26370 73d1a06410f56a203cd80ec28a8d197a 356 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 303 311 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_26665 1a226d8005ee16e8677bed448b9d3ca9 297 SUPERFAMILY SSF81345 12 266 3.27E-31 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_26665 1a226d8005ee16e8677bed448b9d3ca9 297 Pfam PF00950 ABC 3 transport family 17 268 3.0E-42 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A4R43_12630 ef90d9c8c025e3f5334715fa5cdb7826 199 SUPERFAMILY SSF55729 8 157 3.8E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_12630 ef90d9c8c025e3f5334715fa5cdb7826 199 Gene3D G3DSA:3.40.630.30 1 174 7.8E-26 T 14-10-2018 A4R43_12630 ef90d9c8c025e3f5334715fa5cdb7826 199 Pfam PF13302 Acetyltransferase (GNAT) domain 39 128 2.9E-10 T 14-10-2018 IPR000182 GNAT domain A4R43_37240 998729dd0926ac8272b253996cf69aee 614 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 31 439 3.0E-106 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_37240 998729dd0926ac8272b253996cf69aee 614 Gene3D G3DSA:3.30.300.30 410 510 3.8E-28 T 14-10-2018 A4R43_37240 998729dd0926ac8272b253996cf69aee 614 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 496 1.4E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_37240 998729dd0926ac8272b253996cf69aee 614 SMART SM00823 Phosphopantetheine attachment site 524 595 4.8E-9 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37240 998729dd0926ac8272b253996cf69aee 614 ProSitePatterns PS00012 Phosphopantetheine attachment site. 550 565 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site A4R43_37240 998729dd0926ac8272b253996cf69aee 614 Gene3D G3DSA:1.10.1200.10 511 598 1.5E-21 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37240 998729dd0926ac8272b253996cf69aee 614 Gene3D G3DSA:3.40.50.12780 4 407 5.3E-110 T 14-10-2018 A4R43_37240 998729dd0926ac8272b253996cf69aee 614 Pfam PF00550 Phosphopantetheine attachment site 526 591 9.2E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_37240 998729dd0926ac8272b253996cf69aee 614 SUPERFAMILY SSF47336 517 592 5.23E-17 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37240 998729dd0926ac8272b253996cf69aee 614 SUPERFAMILY SSF56801 6 535 4.45E-137 T 14-10-2018 A4R43_37240 998729dd0926ac8272b253996cf69aee 614 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_37240 998729dd0926ac8272b253996cf69aee 614 Pfam PF00501 AMP-binding enzyme 12 414 1.9E-83 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_41355 006aed5e275022eb4f40ff4261278471 249 Pfam PF13489 Methyltransferase domain 15 194 8.3E-16 T 14-10-2018 A4R43_41355 006aed5e275022eb4f40ff4261278471 249 Gene3D G3DSA:3.40.50.150 8 248 9.5E-36 T 14-10-2018 A4R43_41355 006aed5e275022eb4f40ff4261278471 249 SUPERFAMILY SSF53335 30 194 5.58E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_15625 16802f92539ef123e96bebe8d6feaf64 150 SUPERFAMILY SSF54637 9 132 2.06E-29 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_15625 16802f92539ef123e96bebe8d6feaf64 150 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 15 129 9.9E-20 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A4R43_15625 16802f92539ef123e96bebe8d6feaf64 150 Pfam PF03061 Thioesterase superfamily 45 116 1.1E-15 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_15625 16802f92539ef123e96bebe8d6feaf64 150 Gene3D G3DSA:3.10.129.10 5 132 2.4E-34 T 14-10-2018 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 SUPERFAMILY SSF142695 212 384 4.71E-70 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 16 206 9.1E-86 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 212 408 40.587 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 Pfam PF00925 GTP cyclohydrolase II 216 382 1.1E-71 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 PIRSF PIRSF001259 9 412 1.5E-180 T 14-10-2018 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 Gene3D G3DSA:3.40.50.10990 214 386 1.9E-75 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 9 211 39.149 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 SUPERFAMILY SSF55821 14 214 8.7E-81 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A4R43_29790 cac48487b95e193696215d680d7acbe2 422 Gene3D G3DSA:3.90.870.10 3 213 8.0E-90 T 14-10-2018 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 10 404 53.678 T 14-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 207 2.1E-71 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_29790 cac48487b95e193696215d680d7acbe2 422 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 216 406 2.1E-73 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_11220 6ed6aa4a31987cfc184b68b928179e7d 400 SUPERFAMILY SSF103473 11 396 2.09E-55 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_11220 6ed6aa4a31987cfc184b68b928179e7d 400 Gene3D G3DSA:1.20.1250.20 7 392 7.6E-48 T 14-10-2018 A4R43_11220 6ed6aa4a31987cfc184b68b928179e7d 400 Pfam PF07690 Major Facilitator Superfamily 15 261 3.1E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_27470 312171b2d4f0d0c564c8d57044dbd93b 382 Gene3D G3DSA:3.30.565.10 255 380 9.0E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27470 312171b2d4f0d0c564c8d57044dbd93b 382 SUPERFAMILY SSF55874 286 378 1.51E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27470 312171b2d4f0d0c564c8d57044dbd93b 382 Pfam PF07730 Histidine kinase 180 244 1.9E-12 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_33120 4e8eafe25299cc8d6e9e9b2d1ebb6d6a 175 Pfam PF12838 4Fe-4S dicluster domain 52 110 1.4E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_33120 4e8eafe25299cc8d6e9e9b2d1ebb6d6a 175 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_33120 4e8eafe25299cc8d6e9e9b2d1ebb6d6a 175 Gene3D G3DSA:3.30.70.3270 26 172 1.5E-44 T 14-10-2018 A4R43_33120 4e8eafe25299cc8d6e9e9b2d1ebb6d6a 175 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_33120 4e8eafe25299cc8d6e9e9b2d1ebb6d6a 175 SUPERFAMILY SSF54862 26 141 2.03E-25 T 14-10-2018 A4R43_33120 4e8eafe25299cc8d6e9e9b2d1ebb6d6a 175 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 9 136 5.8E-38 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33120 4e8eafe25299cc8d6e9e9b2d1ebb6d6a 175 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 146 26.283 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_20665 b8f30423a1f3ff6f53f8dead2a7034b1 191 Gene3D G3DSA:3.30.420.10 1 170 3.3E-63 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_20665 b8f30423a1f3ff6f53f8dead2a7034b1 191 SMART SM00479 1 168 2.1E-18 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A4R43_20665 b8f30423a1f3ff6f53f8dead2a7034b1 191 SUPERFAMILY SSF53098 1 166 2.53E-37 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_20665 b8f30423a1f3ff6f53f8dead2a7034b1 191 Pfam PF00929 Exonuclease 1 157 2.4E-26 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A4R43_30955 0ef2600d93f8b72a8a656b6510fcf038 390 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 386 2.0E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_30955 0ef2600d93f8b72a8a656b6510fcf038 390 Gene3D G3DSA:3.30.565.10 251 388 1.1E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30955 0ef2600d93f8b72a8a656b6510fcf038 390 Pfam PF07730 Histidine kinase 174 239 2.6E-18 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_30955 0ef2600d93f8b72a8a656b6510fcf038 390 SUPERFAMILY SSF55874 256 385 1.51E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_40905 bd9ed2b9b05d4d4d0810f853ca4d86ec 173 Pfam PF13302 Acetyltransferase (GNAT) domain 5 145 1.1E-23 T 14-10-2018 IPR000182 GNAT domain A4R43_40905 bd9ed2b9b05d4d4d0810f853ca4d86ec 173 Gene3D G3DSA:3.40.630.30 1 157 8.6E-38 T 14-10-2018 A4R43_40905 bd9ed2b9b05d4d4d0810f853ca4d86ec 173 SUPERFAMILY SSF55729 1 149 4.48E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_24205 192b5d4c9e23e5dda94bd7a623af396f 192 SUPERFAMILY SSF46689 6 71 4.36E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_24205 192b5d4c9e23e5dda94bd7a623af396f 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 9.5E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_24205 192b5d4c9e23e5dda94bd7a623af396f 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 9.5E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_24205 192b5d4c9e23e5dda94bd7a623af396f 192 SUPERFAMILY SSF48498 80 184 4.45E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_24205 192b5d4c9e23e5dda94bd7a623af396f 192 Gene3D G3DSA:1.10.357.10 5 183 7.1E-46 T 14-10-2018 A4R43_24205 192b5d4c9e23e5dda94bd7a623af396f 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_24205 192b5d4c9e23e5dda94bd7a623af396f 192 Pfam PF13305 WHG domain 83 161 2.5E-16 T 14-10-2018 IPR025996 WHG domain A4R43_32785 0d6c6992bf31909616bf0a67a177e0c9 294 SUPERFAMILY SSF51430 18 291 5.11E-58 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_32785 0d6c6992bf31909616bf0a67a177e0c9 294 Pfam PF00248 Aldo/keto reductase family 23 291 6.0E-44 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_32785 0d6c6992bf31909616bf0a67a177e0c9 294 PRINTS PR00069 Aldo-keto reductase signature 225 249 8.4E-11 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_32785 0d6c6992bf31909616bf0a67a177e0c9 294 PRINTS PR00069 Aldo-keto reductase signature 154 171 8.4E-11 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_32785 0d6c6992bf31909616bf0a67a177e0c9 294 PRINTS PR00069 Aldo-keto reductase signature 52 76 8.4E-11 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_32785 0d6c6992bf31909616bf0a67a177e0c9 294 Gene3D G3DSA:3.20.20.100 14 294 4.0E-63 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_37870 2fd94fc5ebf0d997484ee36254e9b66d 286 Pfam PF01345 Domain of unknown function DUF11 168 239 1.0E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 A4R43_37870 2fd94fc5ebf0d997484ee36254e9b66d 286 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 174 211 4.6E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 A4R43_13675 8e813c2a22f7d91d1661ea2ae338860c 255 Pfam PF01872 RibD C-terminal domain 38 240 1.7E-36 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_13675 8e813c2a22f7d91d1661ea2ae338860c 255 SUPERFAMILY SSF53597 36 254 2.62E-40 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_13675 8e813c2a22f7d91d1661ea2ae338860c 255 Gene3D G3DSA:3.40.430.10 10 255 5.0E-65 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_30600 9bf223b84e1b62e747c3f56b142d058d 193 SUPERFAMILY SSF143456 9 188 2.35E-49 T 14-10-2018 A4R43_30600 9bf223b84e1b62e747c3f56b142d058d 193 Pfam PF02622 Uncharacterized ACR, COG1678 20 177 1.2E-37 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 A4R43_30600 9bf223b84e1b62e747c3f56b142d058d 193 Gene3D G3DSA:3.40.1740.10 3 184 7.1E-62 T 14-10-2018 A4R43_30600 9bf223b84e1b62e747c3f56b142d058d 193 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 9 190 26.406 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 A4R43_09435 92508c3e1e909de815199f051de69e51 202 SUPERFAMILY SSF48498 95 199 5.66E-15 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_09435 92508c3e1e909de815199f051de69e51 202 SUPERFAMILY SSF46689 14 80 6.16E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_09435 92508c3e1e909de815199f051de69e51 202 Gene3D G3DSA:1.10.357.10 11 202 1.2E-37 T 14-10-2018 A4R43_09435 92508c3e1e909de815199f051de69e51 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 6.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09435 92508c3e1e909de815199f051de69e51 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 6.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09435 92508c3e1e909de815199f051de69e51 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 5.4E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09435 92508c3e1e909de815199f051de69e51 202 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 96 196 3.8E-8 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_13260 a8ed7e2a1489ddde3ac570668d606a78 234 Gene3D G3DSA:1.10.357.10 13 210 5.3E-24 T 14-10-2018 A4R43_13260 a8ed7e2a1489ddde3ac570668d606a78 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 65 1.6E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13260 a8ed7e2a1489ddde3ac570668d606a78 234 SUPERFAMILY SSF46689 16 97 1.42E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13260 a8ed7e2a1489ddde3ac570668d606a78 234 SUPERFAMILY SSF48498 94 202 2.37E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_37525 0b76a25be76fe9d0d4c38f66a53846a9 407 SMART SM00220 1 242 1.3E-10 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_37525 0b76a25be76fe9d0d4c38f66a53846a9 407 SUPERFAMILY SSF56112 2 252 9.6E-36 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_37525 0b76a25be76fe9d0d4c38f66a53846a9 407 Gene3D G3DSA:1.10.510.10 1 266 4.4E-30 T 14-10-2018 A4R43_37525 0b76a25be76fe9d0d4c38f66a53846a9 407 Pfam PF00069 Protein kinase domain 2 230 1.7E-21 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_26895 378ecac88c70a8f0045b26e28eddc14b 422 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 9 419 49.463 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_26895 378ecac88c70a8f0045b26e28eddc14b 422 Pfam PF00464 Serine hydroxymethyltransferase 11 386 7.4E-155 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_26895 378ecac88c70a8f0045b26e28eddc14b 422 PIRSF PIRSF000412 2 422 1.1E-163 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_26895 378ecac88c70a8f0045b26e28eddc14b 422 Gene3D G3DSA:3.90.1150.10 14 393 3.1E-171 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_26895 378ecac88c70a8f0045b26e28eddc14b 422 SUPERFAMILY SSF53383 8 420 1.24E-166 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_26895 378ecac88c70a8f0045b26e28eddc14b 422 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 224 240 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4R43_26895 378ecac88c70a8f0045b26e28eddc14b 422 Gene3D G3DSA:3.40.640.10 39 289 3.1E-171 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_41185 80e33efcb6ecd6a1bdd72ad3314d8c8d 189 SUPERFAMILY SSF55729 5 162 1.17E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_41185 80e33efcb6ecd6a1bdd72ad3314d8c8d 189 Gene3D G3DSA:3.40.630.30 4 178 2.1E-31 T 14-10-2018 A4R43_41185 80e33efcb6ecd6a1bdd72ad3314d8c8d 189 Pfam PF00583 Acetyltransferase (GNAT) family 45 155 2.2E-8 T 14-10-2018 IPR000182 GNAT domain A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SUPERFAMILY SSF52151 555 830 1.07E-45 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Pfam PF00698 Acyl transferase domain 593 807 5.5E-32 T 14-10-2018 IPR014043 Acyl transferase A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 559 854 2.3E-35 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SUPERFAMILY SSF47336 914 993 6.66E-6 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SUPERFAMILY SSF53901 3 384 2.65E-54 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Pfam PF08659 KR domain 1193 1372 5.4E-28 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SUPERFAMILY SSF55048 665 728 1.1E-11 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 271 383 2.3E-28 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Pfam PF14765 Polyketide synthase dehydratase 1440 1719 6.6E-45 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Gene3D G3DSA:1.10.1200.10 903 1000 6.7E-13 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 263 2.6E-43 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SUPERFAMILY SSF54637 1439 1514 1.52E-5 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SUPERFAMILY SSF51735 1185 1443 2.31E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Gene3D G3DSA:3.40.50.720 1024 1422 1.6E-68 T 14-10-2018 A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SMART SM00825 Beta-ketoacyl synthase 2 439 6.6E-37 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1191 1374 1.6E-11 T 14-10-2018 A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 SMART SM00826 1400 1600 5.2E-4 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Gene3D G3DSA:3.10.129.110 1458 1719 1.5E-30 T 14-10-2018 A4R43_37300 52c896e1ee2e26c1f832ee1ee8256375 1922 Gene3D G3DSA:3.40.366.20 463 860 1.9E-92 T 14-10-2018 A4R43_06210 d2f758e4c91ec36dc10218bebb9b294c 202 Gene3D G3DSA:3.40.50.360 5 200 1.7E-17 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_06210 d2f758e4c91ec36dc10218bebb9b294c 202 Pfam PF03358 NADPH-dependent FMN reductase 6 156 1.5E-19 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4R43_06210 d2f758e4c91ec36dc10218bebb9b294c 202 SUPERFAMILY SSF52218 5 180 3.89E-25 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 SUPERFAMILY SSF51905 6 370 6.39E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 3.9E-35 T 14-10-2018 A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 340 3.9E-35 T 14-10-2018 A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 3.9E-35 T 14-10-2018 A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 3.9E-35 T 14-10-2018 A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 3.9E-35 T 14-10-2018 A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 Pfam PF01494 FAD binding domain 5 339 8.4E-71 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 Gene3D G3DSA:3.30.70.2450 180 263 2.9E-98 T 14-10-2018 A4R43_38020 ee7a3d38a0d308a8f7d57a78405f6db8 383 Gene3D G3DSA:3.50.50.60 8 337 2.9E-98 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30945 2af4ce6190fadae9e478c092179cf22b 313 SUPERFAMILY SSF52540 2 219 1.64E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30945 2af4ce6190fadae9e478c092179cf22b 313 Gene3D G3DSA:3.40.50.300 1 232 5.9E-55 T 14-10-2018 A4R43_30945 2af4ce6190fadae9e478c092179cf22b 313 Pfam PF00005 ABC transporter 18 156 3.2E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_30945 2af4ce6190fadae9e478c092179cf22b 313 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_30945 2af4ce6190fadae9e478c092179cf22b 313 SMART SM00382 26 204 3.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_25520 f47760e30849b1592747346ad7d2ab4a 305 SMART SM00382 29 208 1.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_25520 f47760e30849b1592747346ad7d2ab4a 305 Gene3D G3DSA:3.40.50.300 1 230 5.0E-61 T 14-10-2018 A4R43_25520 f47760e30849b1592747346ad7d2ab4a 305 SUPERFAMILY SSF52540 5 223 1.74E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25520 f47760e30849b1592747346ad7d2ab4a 305 Pfam PF13732 Domain of unknown function (DUF4162) 227 296 9.8E-8 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 A4R43_25520 f47760e30849b1592747346ad7d2ab4a 305 Pfam PF00005 ABC transporter 21 160 1.5E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_25520 f47760e30849b1592747346ad7d2ab4a 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_32830 9b05b1f40287481783e8a4f1e9ec96b5 72 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 18 64 1.4E-20 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A4R43_32830 9b05b1f40287481783e8a4f1e9ec96b5 72 Pfam PF12728 Helix-turn-helix domain 18 66 2.5E-15 T 14-10-2018 A4R43_32830 9b05b1f40287481783e8a4f1e9ec96b5 72 Gene3D G3DSA:1.10.1660.10 13 66 3.9E-10 T 14-10-2018 A4R43_32830 9b05b1f40287481783e8a4f1e9ec96b5 72 SUPERFAMILY SSF46955 18 66 2.38E-5 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_33985 149968de2bd2ff61d9729dba2d9fb2ab 134 PIRSF PIRSF002131 4 134 1.1E-53 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4R43_33985 149968de2bd2ff61d9729dba2d9fb2ab 134 Pfam PF00411 Ribosomal protein S11 24 133 5.2E-49 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4R43_33985 149968de2bd2ff61d9729dba2d9fb2ab 134 SUPERFAMILY SSF53137 19 134 1.4E-49 T 14-10-2018 A4R43_33985 149968de2bd2ff61d9729dba2d9fb2ab 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 134 33.885 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4R43_33985 149968de2bd2ff61d9729dba2d9fb2ab 134 Gene3D G3DSA:3.30.420.80 2 134 6.1E-54 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_33985 149968de2bd2ff61d9729dba2d9fb2ab 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site A4R43_33985 149968de2bd2ff61d9729dba2d9fb2ab 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.4E-58 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 Gene3D G3DSA:3.20.20.450 2 231 1.4E-35 T 14-10-2018 IPR035919 EAL domain superfamily A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 SUPERFAMILY SSF141868 4 224 5.75E-33 T 14-10-2018 IPR035919 EAL domain superfamily A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 SUPERFAMILY SSF54631 261 397 9.51E-6 T 14-10-2018 A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 SMART SM00052 2 229 7.5E-9 T 14-10-2018 IPR001633 EAL domain A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 Gene3D G3DSA:3.10.580.10 255 380 4.8E-5 T 14-10-2018 A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 Gene3D G3DSA:3.30.70.270 381 536 6.0E-16 T 14-10-2018 A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 SMART SM00267 378 540 1.1E-5 T 14-10-2018 IPR000160 GGDEF domain A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 SUPERFAMILY SSF55073 394 537 7.85E-14 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 Pfam PF00990 Diguanylate cyclase, GGDEF domain 394 500 1.1E-9 T 14-10-2018 IPR000160 GGDEF domain A4R43_05100 5e34cf91968e7bcbc85e9f7eb928b53c 565 Pfam PF00563 EAL domain 3 224 3.3E-35 T 14-10-2018 IPR001633 EAL domain A4R43_39620 e011b999a2f342a35a600996a4d80edd 537 Pfam PF07905 Purine catabolism regulatory protein-like family 7 129 2.1E-37 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain A4R43_39620 e011b999a2f342a35a600996a4d80edd 537 Pfam PF13556 PucR C-terminal helix-turn-helix domain 471 529 4.1E-14 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_39620 e011b999a2f342a35a600996a4d80edd 537 Gene3D G3DSA:1.10.10.2840 400 534 1.4E-9 T 14-10-2018 A4R43_25570 4a3b7efc862ab84395d0e9fc69285a38 274 Pfam PF00753 Metallo-beta-lactamase superfamily 31 216 2.7E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_25570 4a3b7efc862ab84395d0e9fc69285a38 274 Gene3D G3DSA:3.60.15.10 1 273 1.8E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_25570 4a3b7efc862ab84395d0e9fc69285a38 274 SUPERFAMILY SSF56281 2 266 1.83E-31 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_25570 4a3b7efc862ab84395d0e9fc69285a38 274 SMART SM00849 32 263 1.9E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_31175 117858d75d8ee82cb081487e4e16ad8b 251 Pfam PF00005 ABC transporter 21 169 7.6E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_31175 117858d75d8ee82cb081487e4e16ad8b 251 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_31175 117858d75d8ee82cb081487e4e16ad8b 251 SUPERFAMILY SSF52540 5 239 2.1E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31175 117858d75d8ee82cb081487e4e16ad8b 251 SMART SM00382 30 217 8.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_31175 117858d75d8ee82cb081487e4e16ad8b 251 Gene3D G3DSA:3.40.50.300 5 244 1.6E-77 T 14-10-2018 A4R43_31175 117858d75d8ee82cb081487e4e16ad8b 251 PIRSF PIRSF039085 2 245 1.9E-113 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4R43_19400 2ac1cc9f645ca30ba7f2f6dd77e64809 318 SUPERFAMILY SSF51735 99 286 3.41E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19400 2ac1cc9f645ca30ba7f2f6dd77e64809 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 316 5.3E-31 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_19400 2ac1cc9f645ca30ba7f2f6dd77e64809 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 285 3.7E-60 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_19400 2ac1cc9f645ca30ba7f2f6dd77e64809 318 Gene3D G3DSA:3.40.50.720 96 286 4.2E-114 T 14-10-2018 A4R43_19400 2ac1cc9f645ca30ba7f2f6dd77e64809 318 SUPERFAMILY SSF52283 2 130 1.15E-30 T 14-10-2018 A4R43_19400 2ac1cc9f645ca30ba7f2f6dd77e64809 318 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_19400 2ac1cc9f645ca30ba7f2f6dd77e64809 318 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_19400 2ac1cc9f645ca30ba7f2f6dd77e64809 318 Gene3D G3DSA:3.40.50.720 3 310 4.2E-114 T 14-10-2018 A4R43_33540 8ce4eee3f0709f81e578ce8b0fd4bc3d 402 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 239 252 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4R43_33540 8ce4eee3f0709f81e578ce8b0fd4bc3d 402 Pfam PF00155 Aminotransferase class I and II 35 387 1.0E-71 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_33540 8ce4eee3f0709f81e578ce8b0fd4bc3d 402 SUPERFAMILY SSF53383 7 400 3.23E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_33540 8ce4eee3f0709f81e578ce8b0fd4bc3d 402 Gene3D G3DSA:3.90.1150.10 29 393 1.7E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_33540 8ce4eee3f0709f81e578ce8b0fd4bc3d 402 Gene3D G3DSA:3.40.640.10 67 289 1.7E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_13135 f6619a8ff6abe527137ebddafe8918ec 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 2.8E-8 T 14-10-2018 A4R43_13135 f6619a8ff6abe527137ebddafe8918ec 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 2.8E-8 T 14-10-2018 A4R43_13135 f6619a8ff6abe527137ebddafe8918ec 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 2.8E-8 T 14-10-2018 A4R43_13135 f6619a8ff6abe527137ebddafe8918ec 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 74 96 2.8E-8 T 14-10-2018 A4R43_13135 f6619a8ff6abe527137ebddafe8918ec 451 Pfam PF07690 Major Facilitator Superfamily 17 306 1.9E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_13135 f6619a8ff6abe527137ebddafe8918ec 451 Gene3D G3DSA:1.20.1250.20 4 253 3.8E-37 T 14-10-2018 A4R43_13135 f6619a8ff6abe527137ebddafe8918ec 451 SUPERFAMILY SSF103473 10 448 4.05E-59 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_13135 f6619a8ff6abe527137ebddafe8918ec 451 Gene3D G3DSA:1.20.1250.20 254 450 3.9E-20 T 14-10-2018 A4R43_29380 57105be208e802fb3016b80c8ef59331 143 Pfam PF00011 Hsp20/alpha crystallin family 36 133 3.6E-22 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4R43_29380 57105be208e802fb3016b80c8ef59331 143 SUPERFAMILY SSF49764 6 133 2.88E-32 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_29380 57105be208e802fb3016b80c8ef59331 143 Gene3D G3DSA:2.60.40.790 1 134 1.1E-32 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_14415 3c9795100e41a30427ee5bf05d62bd1c 465 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 17 463 2.8E-118 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4R43_14415 3c9795100e41a30427ee5bf05d62bd1c 465 PIRSF PIRSF002746 10 465 7.6E-151 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4R43_14415 3c9795100e41a30427ee5bf05d62bd1c 465 Pfam PF02447 GntP family permease 16 461 1.8E-129 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4R43_16015 805569550e03540fb2930f8ac9f12667 294 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 162 290 1.9E-19 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16015 805569550e03540fb2930f8ac9f12667 294 Gene3D G3DSA:1.20.140.10 165 293 4.3E-26 T 14-10-2018 A4R43_16015 805569550e03540fb2930f8ac9f12667 294 SUPERFAMILY SSF47203 163 292 7.41E-29 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16015 805569550e03540fb2930f8ac9f12667 294 Gene3D G3DSA:1.10.540.10 2 107 4.3E-6 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SMART SM00862 21 92 8.5E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 PRINTS PR00364 Disease resistance protein signature 288 303 1.0E-7 T 14-10-2018 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 PRINTS PR00364 Disease resistance protein signature 367 381 1.0E-7 T 14-10-2018 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 PRINTS PR00364 Disease resistance protein signature 455 469 1.0E-7 T 14-10-2018 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SMART SM00028 867 900 0.56 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SMART SM00028 189 222 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SMART SM00028 787 820 22.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SMART SM00028 707 740 34.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SMART SM00028 827 860 7.0E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 Gene3D G3DSA:1.25.40.10 98 263 3.1E-45 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SMART SM01043 99 239 3.2E-44 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SUPERFAMILY SSF52540 254 524 5.57E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SUPERFAMILY SSF46894 14 92 2.83E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 Pfam PF00931 NB-ARC domain 286 523 2.7E-7 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 Gene3D G3DSA:1.10.10.10 1 94 2.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 Gene3D G3DSA:1.25.40.10 634 921 4.5E-46 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SUPERFAMILY SSF48452 701 900 5.61E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 SUPERFAMILY SSF48452 95 257 1.81E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 Pfam PF13424 Tetratricopeptide repeat 709 777 1.7E-8 T 14-10-2018 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 Pfam PF13424 Tetratricopeptide repeat 828 899 1.4E-12 T 14-10-2018 A4R43_12355 68e234df6fa1c4e6a9a25c4b296a54e9 921 Pfam PF03704 Bacterial transcriptional activator domain 99 239 5.9E-35 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_25560 fb3f6cb3ba9d11697f3258b0ecdf7639 404 Pfam PF01979 Amidohydrolase family 54 372 8.1E-19 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_25560 fb3f6cb3ba9d11697f3258b0ecdf7639 404 Gene3D G3DSA:2.30.40.10 8 381 1.2E-126 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25560 fb3f6cb3ba9d11697f3258b0ecdf7639 404 Gene3D G3DSA:3.20.20.140 58 347 1.2E-126 T 14-10-2018 A4R43_25560 fb3f6cb3ba9d11697f3258b0ecdf7639 404 SUPERFAMILY SSF51556 57 351 3.46E-49 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_25560 fb3f6cb3ba9d11697f3258b0ecdf7639 404 SUPERFAMILY SSF51338 5 386 7.11E-22 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 PRINTS PR00911 Glycosyl hydrolase family 11 signature 113 122 2.0E-18 T 14-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 PRINTS PR00911 Glycosyl hydrolase family 11 signature 169 174 2.0E-18 T 14-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 PRINTS PR00911 Glycosyl hydrolase family 11 signature 149 155 2.0E-18 T 14-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 PRINTS PR00911 Glycosyl hydrolase family 11 signature 174 183 2.0E-18 T 14-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 PRINTS PR00911 Glycosyl hydrolase family 11 signature 123 133 2.0E-18 T 14-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 PRINTS PR00911 Glycosyl hydrolase family 11 signature 197 205 2.0E-18 T 14-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 Pfam PF00457 Glycosyl hydrolases family 11 51 227 4.6E-76 T 14-10-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 ProSitePatterns PS00777 Glycosyl hydrolases family 11 (GH11) active site signature 2. 213 224 - T 14-10-2018 IPR033119 Glycoside hydrolase family 11, active site 2 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 123 133 - T 14-10-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 SUPERFAMILY SSF49899 41 229 8.13E-79 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_10350 ffad1dbf8999b0f7545a1bde21fb0cf0 229 Gene3D G3DSA:2.60.120.180 36 229 9.4E-83 T 14-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A4R43_08270 fba79c6b675318a019749d478b84fc40 403 Gene3D G3DSA:3.30.1540.10 226 317 6.3E-128 T 14-10-2018 A4R43_08270 fba79c6b675318a019749d478b84fc40 403 Gene3D G3DSA:3.40.50.10540 5 350 6.3E-128 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_08270 fba79c6b675318a019749d478b84fc40 403 Pfam PF02515 CoA-transferase family III 5 368 3.0E-121 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_08270 fba79c6b675318a019749d478b84fc40 403 SUPERFAMILY SSF89796 3 389 3.92E-129 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_05650 d27c9b79c2d42b036397237dae2cf0d9 573 Pfam PF00501 AMP-binding enzyme 51 451 8.3E-75 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_05650 d27c9b79c2d42b036397237dae2cf0d9 573 SUPERFAMILY SSF56801 39 549 3.53E-129 T 14-10-2018 A4R43_05650 d27c9b79c2d42b036397237dae2cf0d9 573 Gene3D G3DSA:3.30.300.310 447 553 1.1E-21 T 14-10-2018 A4R43_05650 d27c9b79c2d42b036397237dae2cf0d9 573 Gene3D G3DSA:3.40.50.12780 18 444 2.5E-114 T 14-10-2018 A4R43_05650 d27c9b79c2d42b036397237dae2cf0d9 573 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_05650 d27c9b79c2d42b036397237dae2cf0d9 573 Pfam PF13193 AMP-binding enzyme C-terminal domain 460 537 6.7E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 ProSitePatterns PS00163 Fumarate lyases signature. 270 279 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 Pfam PF00206 Lyase 51 294 7.6E-24 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 Gene3D G3DSA:1.20.200.10 5 441 3.7E-143 T 14-10-2018 A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 PRINTS PR00149 Fumarate lyase superfamily signature 89 107 3.4E-11 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 3.4E-11 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 PRINTS PR00149 Fumarate lyase superfamily signature 270 286 3.4E-11 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 3.4E-11 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 SUPERFAMILY SSF48557 3 451 9.42E-84 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 SMART SM00998 359 445 9.4E-20 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 2 444 2.3E-129 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 Gene3D G3DSA:1.10.275.60 16 224 3.7E-143 T 14-10-2018 A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 Gene3D G3DSA:1.10.40.30 357 433 3.7E-143 T 14-10-2018 A4R43_31775 d08bf8296476dd63c48e48009d82091b 467 Pfam PF10397 Adenylosuccinate lyase C-terminus 360 442 2.2E-12 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 SMART SM00387 331 441 4.6E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 Gene3D G3DSA:3.30.565.10 294 441 1.1E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 380 1.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 394 1.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 1.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 437 7.0E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 SMART SM00388 225 290 5.7E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 Gene3D G3DSA:1.10.287.130 178 290 2.6E-21 T 14-10-2018 A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 Pfam PF00512 His Kinase A (phospho-acceptor) domain 226 290 2.0E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 SUPERFAMILY SSF47384 208 291 1.16E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_23380 48923fce9f8e2f60db144ee4ced236f9 445 SUPERFAMILY SSF55874 296 438 1.83E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39120 cacd7f23ef1f191797192017f27b511e 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 116 1.2E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_39120 cacd7f23ef1f191797192017f27b511e 126 Gene3D G3DSA:3.10.180.10 6 124 2.6E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_39120 cacd7f23ef1f191797192017f27b511e 126 SUPERFAMILY SSF54593 2 118 3.16E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_18110 5961ceb858f259c14c06da056520c301 192 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 50 4.0E-10 T 14-10-2018 IPR024412 Lsr2 A4R43_18110 5961ceb858f259c14c06da056520c301 192 Pfam PF11774 Lsr2 2 81 8.4E-22 T 14-10-2018 IPR024412 Lsr2 A4R43_18110 5961ceb858f259c14c06da056520c301 192 Gene3D G3DSA:3.30.60.230 1 60 5.0E-23 T 14-10-2018 A4R43_23505 87e9ffe95451d4a5c9289d0ca64bc4b4 73 Gene3D G3DSA:1.10.287.1040 2 71 6.4E-15 T 14-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 A4R43_23505 87e9ffe95451d4a5c9289d0ca64bc4b4 73 SUPERFAMILY SSF116842 3 63 7.98E-17 T 14-10-2018 A4R43_23505 87e9ffe95451d4a5c9289d0ca64bc4b4 73 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 13.769 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4R43_23505 87e9ffe95451d4a5c9289d0ca64bc4b4 73 PIRSF PIRSF006488 1 73 4.9E-23 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4R43_23505 87e9ffe95451d4a5c9289d0ca64bc4b4 73 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 7 60 3.1E-20 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4R43_23505 87e9ffe95451d4a5c9289d0ca64bc4b4 73 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 45 4.0E-12 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4R43_23505 87e9ffe95451d4a5c9289d0ca64bc4b4 73 Pfam PF02609 Exonuclease VII small subunit 7 57 2.4E-17 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4R43_00920 264c3d8059c2fa8fa4733f6b8b28d415 329 Gene3D G3DSA:3.40.50.720 2 272 8.6E-41 T 14-10-2018 A4R43_00920 264c3d8059c2fa8fa4733f6b8b28d415 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 229 9.2E-21 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_00920 264c3d8059c2fa8fa4733f6b8b28d415 329 SUPERFAMILY SSF51735 1 306 9.34E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 291 1.5E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 402 579 1.2E-6 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 SUPERFAMILY SSF161098 28 304 5.1E-45 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 SUPERFAMILY SSF161098 321 581 6.15E-38 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 PRINTS PR00173 Glutamate-aspartate symporter signature 440 459 1.4E-6 T 14-10-2018 A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 PRINTS PR00173 Glutamate-aspartate symporter signature 559 578 1.4E-6 T 14-10-2018 A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 PRINTS PR00173 Glutamate-aspartate symporter signature 219 239 1.4E-6 T 14-10-2018 A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 Gene3D G3DSA:1.10.3720.10 323 584 4.0E-32 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_02045 27ce9b3b9943767f29aa46a33dd884a4 586 Gene3D G3DSA:1.10.3720.10 32 303 6.2E-44 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_12360 ff0f17c58740d2f5b8fb023bdf4fbefa 118 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 7 100 2.6E-6 T 14-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 SUPERFAMILY SSF52374 27 336 5.09E-70 T 14-10-2018 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 53.551 T 14-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 8.5E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 244 265 8.5E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 213 231 8.5E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 8.5E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 Gene3D G3DSA:3.40.50.620 1 329 9.9E-100 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 3 411 1.7E-211 T 14-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 38 336 2.4E-81 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A4R43_10960 8fe33e965baec5776e48afe6d7088b1d 412 Gene3D G3DSA:1.20.120.640 330 412 6.2E-29 T 14-10-2018 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 SMART SM00244 19 177 5.7E-58 T 14-10-2018 IPR001107 Band 7 domain A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 SUPERFAMILY SSF117892 51 184 6.41E-41 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 Gene3D G3DSA:3.30.479.30 48 179 1.3E-45 T 14-10-2018 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 PRINTS PR00721 Stomatin signature 197 220 1.1E-57 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 PRINTS PR00721 Stomatin signature 74 95 1.1E-57 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 PRINTS PR00721 Stomatin signature 172 193 1.1E-57 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 PRINTS PR00721 Stomatin signature 26 48 1.1E-57 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 PRINTS PR00721 Stomatin signature 153 171 1.1E-57 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 PRINTS PR00721 Stomatin signature 109 126 1.1E-57 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 PRINTS PR00721 Stomatin signature 129 152 1.1E-57 T 14-10-2018 IPR001972 Stomatin family GO:0016020 A4R43_35690 b4a868cdc4776a17ee58fd31bf476cf3 275 Pfam PF01145 SPFH domain / Band 7 family 23 193 3.8E-33 T 14-10-2018 IPR001107 Band 7 domain A4R43_10005 702a9214ea2f189c27ce41140c46519c 392 Gene3D G3DSA:2.120.10.30 40 389 5.4E-80 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_10005 702a9214ea2f189c27ce41140c46519c 392 Pfam PF07995 Glucose / Sorbosone dehydrogenase 53 329 1.2E-37 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_10005 702a9214ea2f189c27ce41140c46519c 392 SUPERFAMILY SSF50952 47 388 5.36E-31 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_26450 aff9c9367b10816948d0077784f80a9d 184 Pfam PF04542 Sigma-70 region 2 25 91 1.3E-14 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_26450 aff9c9367b10816948d0077784f80a9d 184 Gene3D G3DSA:1.10.1740.10 1 86 5.7E-27 T 14-10-2018 A4R43_26450 aff9c9367b10816948d0077784f80a9d 184 SUPERFAMILY SSF88659 112 170 1.37E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_26450 aff9c9367b10816948d0077784f80a9d 184 Pfam PF08281 Sigma-70, region 4 116 166 1.3E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_26450 aff9c9367b10816948d0077784f80a9d 184 SUPERFAMILY SSF88946 2 104 4.71E-22 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_26450 aff9c9367b10816948d0077784f80a9d 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 169 4.7E-21 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_26450 aff9c9367b10816948d0077784f80a9d 184 Gene3D G3DSA:1.10.10.10 111 174 1.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09380 071c385af222e591c9cf5b9471f9421b 328 Gene3D G3DSA:3.40.50.1980 46 168 3.3E-15 T 14-10-2018 A4R43_09380 071c385af222e591c9cf5b9471f9421b 328 SUPERFAMILY SSF53807 51 310 1.22E-40 T 14-10-2018 A4R43_09380 071c385af222e591c9cf5b9471f9421b 328 Gene3D G3DSA:3.40.50.1980 178 326 1.5E-16 T 14-10-2018 A4R43_09380 071c385af222e591c9cf5b9471f9421b 328 Pfam PF01497 Periplasmic binding protein 70 303 1.0E-18 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_03940 4ef9d7ff007ba5967b1af24b63cbf9cb 392 Gene3D G3DSA:2.130.10.10 261 390 1.5E-6 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_03940 4ef9d7ff007ba5967b1af24b63cbf9cb 392 SUPERFAMILY SSF50969 49 387 1.18E-22 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A4R43_03940 4ef9d7ff007ba5967b1af24b63cbf9cb 392 Gene3D G3DSA:2.130.10.10 43 242 6.3E-7 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_10765 ced3beffab64e405df401e00fdb50025 493 SMART SM00046 203 333 1.2E-6 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4R43_10765 ced3beffab64e405df401e00fdb50025 493 Gene3D G3DSA:3.40.50.10330 198 323 2.7E-14 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A4R43_10765 ced3beffab64e405df401e00fdb50025 493 Gene3D G3DSA:2.60.200.40 329 481 3.6E-19 T 14-10-2018 A4R43_10765 ced3beffab64e405df401e00fdb50025 493 Pfam PF00781 Diacylglycerol kinase catalytic domain 204 308 6.5E-16 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4R43_10765 ced3beffab64e405df401e00fdb50025 493 SUPERFAMILY SSF111331 203 491 2.16E-46 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A4R43_10765 ced3beffab64e405df401e00fdb50025 493 SMART SM00014 67 176 1.2E-20 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_10765 ced3beffab64e405df401e00fdb50025 493 Pfam PF01569 PAP2 superfamily 70 179 8.1E-16 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_10765 ced3beffab64e405df401e00fdb50025 493 SUPERFAMILY SSF48317 18 179 1.44E-32 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4R43_10765 ced3beffab64e405df401e00fdb50025 493 Gene3D G3DSA:1.20.144.10 23 194 3.7E-16 T 14-10-2018 A4R43_38060 662dbe56314e38b4a0cc5a31bbb3b15e 569 Pfam PF00732 GMC oxidoreductase 5 272 3.1E-12 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4R43_38060 662dbe56314e38b4a0cc5a31bbb3b15e 569 Gene3D G3DSA:3.50.50.60 180 322 1.8E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38060 662dbe56314e38b4a0cc5a31bbb3b15e 569 Gene3D G3DSA:3.50.50.60 426 516 1.5E-18 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38060 662dbe56314e38b4a0cc5a31bbb3b15e 569 SUPERFAMILY SSF51905 1 516 3.2E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38060 662dbe56314e38b4a0cc5a31bbb3b15e 569 Pfam PF05199 GMC oxidoreductase 454 511 1.1E-13 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_38060 662dbe56314e38b4a0cc5a31bbb3b15e 569 Gene3D G3DSA:3.50.50.60 3 160 1.0E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_15480 9d7b438cff79025543d962b1895ed7b5 281 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 258 3.6E-74 T 14-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted A4R43_15480 9d7b438cff79025543d962b1895ed7b5 281 SUPERFAMILY SSF51679 18 259 4.19E-56 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_15480 9d7b438cff79025543d962b1895ed7b5 281 Pfam PF00296 Luciferase-like monooxygenase 18 233 9.6E-49 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_15480 9d7b438cff79025543d962b1895ed7b5 281 Gene3D G3DSA:3.20.20.30 3 277 2.7E-62 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_27820 ede21f311b765aafbc4210f203887cff 501 Pfam PF07728 AAA domain (dynein-related subfamily) 188 370 2.6E-10 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A4R43_27820 ede21f311b765aafbc4210f203887cff 501 SUPERFAMILY SSF52540 172 422 1.83E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27820 ede21f311b765aafbc4210f203887cff 501 SMART SM00382 184 376 1.0E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 2.3E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 131 154 2.3E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 2.3E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 2.3E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 2.3E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.3E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 SUPERFAMILY SSF56655 5 261 8.25E-61 T 14-10-2018 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 Gene3D G3DSA:3.30.540.10 2 140 4.8E-33 T 14-10-2018 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 Gene3D G3DSA:3.40.190.80 143 279 3.9E-28 T 14-10-2018 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4R43_29285 6e764ded75d30b1702655595fa1c1133 292 Pfam PF00459 Inositol monophosphatase family 8 254 4.0E-52 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_07235 9085501652e9604cfd6f87eb05272b32 228 Pfam PF06197 Protein of unknown function (DUF998) 31 217 7.1E-33 T 14-10-2018 IPR009339 Protein of unknown function DUF998 A4R43_35430 6c5552fd9bc1fa287550110e5bb47b4f 833 SUPERFAMILY SSF53448 6 231 7.88E-51 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35430 6c5552fd9bc1fa287550110e5bb47b4f 833 Pfam PF13641 Glycosyltransferase like family 2 9 225 1.0E-18 T 14-10-2018 A4R43_35430 6c5552fd9bc1fa287550110e5bb47b4f 833 Pfam PF13692 Glycosyl transferases group 1 582 737 1.9E-11 T 14-10-2018 A4R43_35430 6c5552fd9bc1fa287550110e5bb47b4f 833 Gene3D G3DSA:3.40.50.2000 571 757 5.3E-23 T 14-10-2018 A4R43_35430 6c5552fd9bc1fa287550110e5bb47b4f 833 Gene3D G3DSA:3.90.550.10 2 229 6.9E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35430 6c5552fd9bc1fa287550110e5bb47b4f 833 SUPERFAMILY SSF53756 379 771 6.28E-25 T 14-10-2018 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 Gene3D G3DSA:1.10.10.1320 197 254 1.4E-8 T 14-10-2018 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 SUPERFAMILY SSF88946 8 101 6.87E-18 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 184 1.5E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 Pfam PF13490 Putative zinc-finger 198 232 2.5E-7 T 14-10-2018 IPR027383 Putative zinc-finger A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 Gene3D G3DSA:1.10.1740.10 8 120 7.3E-17 T 14-10-2018 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 PRINTS PR01217 Proline rich extensin signature 390 407 1.1E-9 T 14-10-2018 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 PRINTS PR01217 Proline rich extensin signature 373 389 1.1E-9 T 14-10-2018 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 PRINTS PR01217 Proline rich extensin signature 335 347 1.1E-9 T 14-10-2018 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 PRINTS PR01217 Proline rich extensin signature 351 372 1.1E-9 T 14-10-2018 A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 Gene3D G3DSA:1.10.10.10 121 186 9.2E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 SUPERFAMILY SSF88659 122 184 1.68E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_35280 780d383098a8bf7f495c8dff14335b6d 747 Pfam PF04542 Sigma-70 region 2 31 98 6.8E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_38480 22a1255a248715ad3b17a218f342de5d 464 SUPERFAMILY SSF53756 11 455 2.79E-67 T 14-10-2018 A4R43_38480 22a1255a248715ad3b17a218f342de5d 464 Gene3D G3DSA:3.40.50.2000 281 446 1.9E-35 T 14-10-2018 A4R43_38480 22a1255a248715ad3b17a218f342de5d 464 Gene3D G3DSA:3.40.50.2000 2 280 3.0E-20 T 14-10-2018 A4R43_38480 22a1255a248715ad3b17a218f342de5d 464 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 108 443 1.3E-24 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_09000 9694bd197f5983cec244b258ec4bd640 438 Pfam PF01546 Peptidase family M20/M25/M40 77 435 1.3E-36 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_09000 9694bd197f5983cec244b258ec4bd640 438 SUPERFAMILY SSF53187 4 435 3.43E-57 T 14-10-2018 A4R43_09000 9694bd197f5983cec244b258ec4bd640 438 Pfam PF07687 Peptidase dimerisation domain 199 328 2.0E-11 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_09000 9694bd197f5983cec244b258ec4bd640 438 SUPERFAMILY SSF55031 202 326 1.23E-8 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_09000 9694bd197f5983cec244b258ec4bd640 438 Gene3D G3DSA:3.40.630.10 3 204 6.0E-51 T 14-10-2018 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 243 259 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 Gene3D G3DSA:1.20.58.410 3 114 3.1E-26 T 14-10-2018 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 4 361 5.0E-157 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 Pfam PF00472 RF-1 domain 227 334 9.2E-38 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 SMART SM00937 83 193 2.9E-47 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 SUPERFAMILY SSF75620 28 363 1.07E-120 T 14-10-2018 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 Gene3D G3DSA:3.30.70.1660 128 355 2.3E-89 T 14-10-2018 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 362 37.192 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 Gene3D G3DSA:3.30.160.20 224 317 2.3E-89 T 14-10-2018 A4R43_21995 c8836e5234eb1f09e9657f4c2f00f620 367 Pfam PF03462 PCRF domain 29 218 4.1E-56 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 SUPERFAMILY SSF53474 5 286 3.33E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 8.6E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 8.6E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 8.6E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 8.6E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 Gene3D G3DSA:3.40.50.1820 4 287 1.0E-70 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00412 Epoxide hydrolase signature 263 285 3.3E-14 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00412 Epoxide hydrolase signature 102 115 3.3E-14 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00412 Epoxide hydrolase signature 53 68 3.3E-14 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00412 Epoxide hydrolase signature 33 51 3.3E-14 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 PRINTS PR00412 Epoxide hydrolase signature 116 129 3.3E-14 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_02695 ee88c7a7ec7c04da5bcf03171236c1c2 287 Pfam PF00561 alpha/beta hydrolase fold 27 240 4.8E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_19475 52f84ccb8576565bf4d2b90f13d6a3b4 209 Gene3D G3DSA:3.30.565.10 70 160 4.8E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_19475 52f84ccb8576565bf4d2b90f13d6a3b4 209 Gene3D G3DSA:1.10.287.130 18 69 4.8E-18 T 14-10-2018 A4R43_19475 52f84ccb8576565bf4d2b90f13d6a3b4 209 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 111 198 3.0E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_19475 52f84ccb8576565bf4d2b90f13d6a3b4 209 SUPERFAMILY SSF55874 77 199 1.22E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_19475 52f84ccb8576565bf4d2b90f13d6a3b4 209 SMART SM00387 110 204 4.5E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_37955 4d67e09927a3a2d6aa185fa9810b3676 501 Gene3D G3DSA:3.30.300.310 410 501 2.1E-25 T 14-10-2018 A4R43_37955 4d67e09927a3a2d6aa185fa9810b3676 501 Pfam PF00501 AMP-binding enzyme 16 409 2.5E-77 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_37955 4d67e09927a3a2d6aa185fa9810b3676 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 490 4.4E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_37955 4d67e09927a3a2d6aa185fa9810b3676 501 Gene3D G3DSA:2.30.38.10 303 409 9.7E-33 T 14-10-2018 A4R43_37955 4d67e09927a3a2d6aa185fa9810b3676 501 SUPERFAMILY SSF56801 16 499 9.68E-130 T 14-10-2018 A4R43_37955 4d67e09927a3a2d6aa185fa9810b3676 501 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 6 498 6.5E-137 T 14-10-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 A4R43_37955 4d67e09927a3a2d6aa185fa9810b3676 501 Gene3D G3DSA:3.40.50.980 4 231 3.2E-44 T 14-10-2018 A4R43_37955 4d67e09927a3a2d6aa185fa9810b3676 501 Gene3D G3DSA:1.10.10.2900 232 302 1.8E-27 T 14-10-2018 A4R43_36405 4e73cc9a0fbafe25d196d6eda6eebc00 131 Pfam PF01638 HxlR-like helix-turn-helix 27 113 1.1E-24 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_36405 4e73cc9a0fbafe25d196d6eda6eebc00 131 Gene3D G3DSA:1.10.10.10 4 126 3.0E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36405 4e73cc9a0fbafe25d196d6eda6eebc00 131 SUPERFAMILY SSF46785 15 123 1.26E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08070 c71a12c92cf541f2b4f5ce3ae52502ee 272 Gene3D G3DSA:3.60.10.10 1 253 1.9E-34 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_08070 c71a12c92cf541f2b4f5ce3ae52502ee 272 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 245 4.0E-14 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4R43_08070 c71a12c92cf541f2b4f5ce3ae52502ee 272 SUPERFAMILY SSF56219 1 253 1.31E-28 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_11790 9cdb0381facde7b49b8b1f6a32b443cc 354 Pfam PF02470 MlaD protein 30 104 1.3E-12 T 14-10-2018 IPR003399 Mce/MlaD A4R43_11790 9cdb0381facde7b49b8b1f6a32b443cc 354 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 8 284 2.0E-53 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11730 c07f5b1b3f93a06033f5f62f8cd4bb69 453 Pfam PF07690 Major Facilitator Superfamily 42 391 3.3E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_11730 c07f5b1b3f93a06033f5f62f8cd4bb69 453 ProSitePatterns PS00216 Sugar transport proteins signature 1. 305 321 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_11730 c07f5b1b3f93a06033f5f62f8cd4bb69 453 SUPERFAMILY SSF103473 14 437 3.79E-71 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_11730 c07f5b1b3f93a06033f5f62f8cd4bb69 453 ProSitePatterns PS00217 Sugar transport proteins signature 2. 133 158 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_11730 c07f5b1b3f93a06033f5f62f8cd4bb69 453 Gene3D G3DSA:1.20.1250.20 21 439 3.4E-72 T 14-10-2018 A4R43_23170 467f7b31ea4fcbb497f9cdfde8af969f 276 Gene3D G3DSA:2.50.20.20 40 264 4.8E-9 T 14-10-2018 A4R43_23170 467f7b31ea4fcbb497f9cdfde8af969f 276 SUPERFAMILY SSF89392 47 264 2.24E-8 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4R43_21820 1423f1097d6faa955a49503b3892a63d 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 53 3.5E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21820 1423f1097d6faa955a49503b3892a63d 196 Gene3D G3DSA:1.10.357.10 4 185 7.7E-44 T 14-10-2018 A4R43_21820 1423f1097d6faa955a49503b3892a63d 196 SUPERFAMILY SSF46689 5 62 2.1E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21820 1423f1097d6faa955a49503b3892a63d 196 SUPERFAMILY SSF48498 95 170 2.45E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_38650 452ac14caea68a0a171a5863bbfebd3b 399 Gene3D G3DSA:3.40.50.2000 211 376 4.0E-98 T 14-10-2018 A4R43_38650 452ac14caea68a0a171a5863bbfebd3b 399 Gene3D G3DSA:3.40.50.2000 3 378 4.0E-98 T 14-10-2018 A4R43_38650 452ac14caea68a0a171a5863bbfebd3b 399 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 233 371 1.8E-7 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_38650 452ac14caea68a0a171a5863bbfebd3b 399 SUPERFAMILY SSF53756 1 392 4.54E-82 T 14-10-2018 A4R43_38650 452ac14caea68a0a171a5863bbfebd3b 399 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 70 3.2E-6 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_21560 ed946783033bb233ee14fb9706d9c02c 280 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 48 277 3.1E-45 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 A4R43_21560 ed946783033bb233ee14fb9706d9c02c 280 Gene3D G3DSA:3.60.130.10 16 280 2.0E-78 T 14-10-2018 A4R43_21560 ed946783033bb233ee14fb9706d9c02c 280 SUPERFAMILY SSF51197 29 279 1.51E-49 T 14-10-2018 A4R43_02475 68170fc553a4c0aa6ddd5d0d16fa734d 417 Pfam PF07690 Major Facilitator Superfamily 215 391 2.1E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_02475 68170fc553a4c0aa6ddd5d0d16fa734d 417 Pfam PF07690 Major Facilitator Superfamily 17 202 9.2E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_02475 68170fc553a4c0aa6ddd5d0d16fa734d 417 SUPERFAMILY SSF103473 7 392 4.19E-45 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_02475 68170fc553a4c0aa6ddd5d0d16fa734d 417 Gene3D G3DSA:1.20.1250.20 206 396 2.0E-19 T 14-10-2018 A4R43_02475 68170fc553a4c0aa6ddd5d0d16fa734d 417 Gene3D G3DSA:1.20.1250.20 5 193 8.3E-23 T 14-10-2018 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 Gene3D G3DSA:2.40.110.10 124 233 4.7E-38 T 14-10-2018 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 121 1.1E-36 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 SUPERFAMILY SSF56645 5 240 1.13E-81 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 PIRSF PIRSF016578 130 384 1.8E-13 T 14-10-2018 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 PIRSF PIRSF016578 8 110 1.1E-5 T 14-10-2018 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 Gene3D G3DSA:1.10.540.10 2 123 1.3E-40 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 Gene3D G3DSA:1.20.140.10 234 386 3.1E-53 T 14-10-2018 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 216 3.2E-28 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 379 2.3E-42 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_21330 ee821780c6a0f5ff4d436df95d39fb79 386 SUPERFAMILY SSF47203 226 381 1.18E-51 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_24655 ec4063f98e6634deb8f46b7881713c96 70 Pfam PF04070 Domain of unknown function (DUF378) 6 60 4.2E-8 T 14-10-2018 IPR007211 Protein of unknown function DUF378 A4R43_02645 475720e50ca0f0494456b13fc0b2e5ab 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 5.8E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_02645 475720e50ca0f0494456b13fc0b2e5ab 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 5.8E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_02645 475720e50ca0f0494456b13fc0b2e5ab 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 1.9E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_02645 475720e50ca0f0494456b13fc0b2e5ab 228 SUPERFAMILY SSF48498 78 143 4.45E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_02645 475720e50ca0f0494456b13fc0b2e5ab 228 Gene3D G3DSA:1.10.357.10 1 159 8.0E-33 T 14-10-2018 A4R43_02645 475720e50ca0f0494456b13fc0b2e5ab 228 SUPERFAMILY SSF46689 3 73 7.98E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03945 8a02749db0538086f921ae9a850163c1 224 Pfam PF02254 TrkA-N domain 6 120 3.8E-20 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4R43_03945 8a02749db0538086f921ae9a850163c1 224 SUPERFAMILY SSF51735 3 141 2.96E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03945 8a02749db0538086f921ae9a850163c1 224 Gene3D G3DSA:3.40.50.720 4 138 4.2E-23 T 14-10-2018 A4R43_41750 096a2682a4da0a8fbcc825efa42ca74b 355 Pfam PF01513 ATP-NAD kinase 1 159 1.6E-15 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A4R43_41750 096a2682a4da0a8fbcc825efa42ca74b 355 Gene3D G3DSA:3.40.50.10330 79 171 1.7E-5 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A4R43_41750 096a2682a4da0a8fbcc825efa42ca74b 355 PIRSF PIRSF018567 1 339 3.0E-103 T 14-10-2018 IPR011391 Acetoin catabolism kinase AcoX A4R43_41750 096a2682a4da0a8fbcc825efa42ca74b 355 SUPERFAMILY SSF111331 86 142 1.83E-7 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A4R43_24185 c21e02db0ba0384c491546001d2083ed 507 Pfam PF00171 Aldehyde dehydrogenase family 31 494 1.9E-160 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_24185 c21e02db0ba0384c491546001d2083ed 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_24185 c21e02db0ba0384c491546001d2083ed 507 Gene3D G3DSA:3.40.605.10 37 492 2.5E-159 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_24185 c21e02db0ba0384c491546001d2083ed 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_24185 c21e02db0ba0384c491546001d2083ed 507 Gene3D G3DSA:3.40.309.10 266 464 2.5E-159 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_24185 c21e02db0ba0384c491546001d2083ed 507 SUPERFAMILY SSF53720 13 499 2.36E-158 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_39510 ed65cc6121472b3f427ba69372982b3a 231 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 24 230 2.2E-59 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A4R43_39510 ed65cc6121472b3f427ba69372982b3a 231 SUPERFAMILY SSF52402 14 195 3.07E-38 T 14-10-2018 A4R43_39510 ed65cc6121472b3f427ba69372982b3a 231 Gene3D G3DSA:3.40.50.620 3 231 2.3E-65 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_39510 ed65cc6121472b3f427ba69372982b3a 231 PIRSF PIRSF000857 2 231 3.0E-88 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A4R43_39510 ed65cc6121472b3f427ba69372982b3a 231 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 42 229 3.1E-72 T 14-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 A4R43_39510 ed65cc6121472b3f427ba69372982b3a 231 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 41 206 1.7E-41 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A4R43_32800 03c3d649f769b1a2dc3a3fc58a57a8cd 332 SUPERFAMILY SSF53067 129 306 6.47E-34 T 14-10-2018 A4R43_32800 03c3d649f769b1a2dc3a3fc58a57a8cd 332 Pfam PF02541 Ppx/GppA phosphatase family 17 305 3.8E-73 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4R43_32800 03c3d649f769b1a2dc3a3fc58a57a8cd 332 Gene3D G3DSA:3.30.420.40 5 300 6.5E-77 T 14-10-2018 A4R43_32800 03c3d649f769b1a2dc3a3fc58a57a8cd 332 Gene3D G3DSA:3.30.420.150 108 293 6.5E-77 T 14-10-2018 A4R43_32800 03c3d649f769b1a2dc3a3fc58a57a8cd 332 SUPERFAMILY SSF53067 2 125 1.43E-29 T 14-10-2018 A4R43_23235 eb6ea558b11f2551c5bf3579fc3a953c 261 SUPERFAMILY SSF55781 71 258 7.85E-50 T 14-10-2018 A4R43_23235 eb6ea558b11f2551c5bf3579fc3a953c 261 Gene3D G3DSA:3.30.450.40 87 261 2.3E-54 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_23235 eb6ea558b11f2551c5bf3579fc3a953c 261 Gene3D G3DSA:1.10.10.10 12 86 3.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23235 eb6ea558b11f2551c5bf3579fc3a953c 261 Pfam PF01614 Bacterial transcriptional regulator 132 254 9.6E-35 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_23235 eb6ea558b11f2551c5bf3579fc3a953c 261 SUPERFAMILY SSF46785 14 85 8.47E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_23235 eb6ea558b11f2551c5bf3579fc3a953c 261 Pfam PF09339 IclR helix-turn-helix domain 16 65 2.3E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_23235 eb6ea558b11f2551c5bf3579fc3a953c 261 SMART SM00346 14 103 1.2E-18 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_40430 69c5cc41b99b07cd88b50f4ce22d538b 136 SUPERFAMILY SSF54637 3 134 9.58E-35 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_40430 69c5cc41b99b07cd88b50f4ce22d538b 136 Pfam PF03061 Thioesterase superfamily 21 103 2.3E-11 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_40430 69c5cc41b99b07cd88b50f4ce22d538b 136 Gene3D G3DSA:3.10.129.10 2 135 3.8E-44 T 14-10-2018 A4R43_10990 68178b126720d5b5eaab0211d5bee606 361 Pfam PF13358 DDE superfamily endonuclease 173 318 2.9E-23 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain A4R43_10990 68178b126720d5b5eaab0211d5bee606 361 Pfam PF13551 Winged helix-turn helix 35 95 1.9E-14 T 14-10-2018 A4R43_10990 68178b126720d5b5eaab0211d5bee606 361 SUPERFAMILY SSF46689 25 136 8.78E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_32390 b45685f1851e95a173bf2124cd3af4d0 553 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_32390 b45685f1851e95a173bf2124cd3af4d0 553 Gene3D G3DSA:3.40.50.300 322 553 3.7E-59 T 14-10-2018 A4R43_32390 b45685f1851e95a173bf2124cd3af4d0 553 SUPERFAMILY SSF90123 6 311 1.44E-42 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_32390 b45685f1851e95a173bf2124cd3af4d0 553 SMART SM00382 345 528 5.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_32390 b45685f1851e95a173bf2124cd3af4d0 553 Gene3D G3DSA:1.20.1560.10 4 311 8.8E-39 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_32390 b45685f1851e95a173bf2124cd3af4d0 553 SUPERFAMILY SSF52540 322 544 3.55E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_32390 b45685f1851e95a173bf2124cd3af4d0 553 Pfam PF00005 ABC transporter 336 482 1.6E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_32390 b45685f1851e95a173bf2124cd3af4d0 553 Pfam PF00664 ABC transporter transmembrane region 19 278 8.4E-17 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 6.1E-17 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 6.1E-17 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 6.1E-17 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 6.1E-17 T 14-10-2018 IPR000362 Fumarate lyase family A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 SUPERFAMILY SSF158682 541 594 2.88E-7 T 14-10-2018 IPR029024 TerB-like A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 Gene3D G3DSA:1.20.200.10 142 404 1.2E-77 T 14-10-2018 A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 SUPERFAMILY SSF48557 5 454 2.04E-98 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 SUPERFAMILY SSF158682 460 529 2.35E-7 T 14-10-2018 IPR029024 TerB-like A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 Pfam PF00206 Lyase 13 339 2.9E-61 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 Gene3D G3DSA:1.10.275.10 3 141 2.0E-45 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 Pfam PF05099 Tellurite resistance protein TerB 451 524 1.6E-6 T 14-10-2018 IPR007791 Co-chaperone DjlA, N-terminal A4R43_32540 1e75c31e70999d0c9e8a02dc4691479c 628 Pfam PF10415 Fumarase C C-terminus 408 457 6.9E-7 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_15415 80bd43c74f6bc9508698e46255f60f6f 202 SUPERFAMILY SSF48498 79 195 4.08E-27 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_15415 80bd43c74f6bc9508698e46255f60f6f 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 188 3.2E-33 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_15415 80bd43c74f6bc9508698e46255f60f6f 202 SUPERFAMILY SSF46689 16 72 3.94E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_15415 80bd43c74f6bc9508698e46255f60f6f 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 9.2E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15415 80bd43c74f6bc9508698e46255f60f6f 202 Gene3D G3DSA:1.10.357.10 60 198 1.9E-35 T 14-10-2018 A4R43_15415 80bd43c74f6bc9508698e46255f60f6f 202 Gene3D G3DSA:1.10.10.60 14 59 6.7E-16 T 14-10-2018 A4R43_31750 2391042be6fbda791bf6f4f5fdb2d2ce 204 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 177 4.3E-16 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_31750 2391042be6fbda791bf6f4f5fdb2d2ce 204 SUPERFAMILY SSF56784 2 190 5.66E-31 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_31750 2391042be6fbda791bf6f4f5fdb2d2ce 204 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 3.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_31750 2391042be6fbda791bf6f4f5fdb2d2ce 204 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 7 3.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_31750 2391042be6fbda791bf6f4f5fdb2d2ce 204 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 3.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_31750 2391042be6fbda791bf6f4f5fdb2d2ce 204 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 95 108 3.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_31750 2391042be6fbda791bf6f4f5fdb2d2ce 204 Pfam PF00702 haloacid dehalogenase-like hydrolase 9 175 1.1E-10 T 14-10-2018 A4R43_31750 2391042be6fbda791bf6f4f5fdb2d2ce 204 Gene3D G3DSA:3.40.50.1000 1 192 1.5E-33 T 14-10-2018 IPR023214 HAD superfamily A4R43_01350 d14cb17287aea45999dc5d7651242d99 228 Gene3D G3DSA:1.10.357.10 24 218 1.2E-27 T 14-10-2018 A4R43_01350 d14cb17287aea45999dc5d7651242d99 228 SUPERFAMILY SSF46689 30 98 9.23E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01350 d14cb17287aea45999dc5d7651242d99 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 4.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01350 d14cb17287aea45999dc5d7651242d99 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 4.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01350 d14cb17287aea45999dc5d7651242d99 228 SUPERFAMILY SSF48498 148 220 3.15E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_01350 d14cb17287aea45999dc5d7651242d99 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 84 1.5E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16655 84b83efd7594c1297f18d5450e1a28c7 393 Gene3D G3DSA:2.40.110.10 126 234 1.5E-32 T 14-10-2018 A4R43_16655 84b83efd7594c1297f18d5450e1a28c7 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 385 2.1E-35 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16655 84b83efd7594c1297f18d5450e1a28c7 393 SUPERFAMILY SSF56645 4 244 6.81E-65 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16655 84b83efd7594c1297f18d5450e1a28c7 393 SUPERFAMILY SSF47203 231 390 3.54E-25 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16655 84b83efd7594c1297f18d5450e1a28c7 393 Gene3D G3DSA:1.20.140.10 235 392 2.9E-40 T 14-10-2018 A4R43_16655 84b83efd7594c1297f18d5450e1a28c7 393 Gene3D G3DSA:1.10.540.10 2 121 7.0E-33 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16655 84b83efd7594c1297f18d5450e1a28c7 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 122 1.2E-22 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_16655 84b83efd7594c1297f18d5450e1a28c7 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 214 5.5E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_09760 2f3fc2ee517b54ba380798a3b7c2d5a0 496 Pfam PF04616 Glycosyl hydrolases family 43 38 321 5.5E-58 T 14-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4R43_09760 2f3fc2ee517b54ba380798a3b7c2d5a0 496 Pfam PF06439 Domain of Unknown Function (DUF1080) 334 493 8.2E-7 T 14-10-2018 IPR010496 Domain of unknown function DUF1080 A4R43_09760 2f3fc2ee517b54ba380798a3b7c2d5a0 496 SUPERFAMILY SSF75005 36 321 5.76E-73 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_09760 2f3fc2ee517b54ba380798a3b7c2d5a0 496 Gene3D G3DSA:2.60.120.560 332 492 3.1E-31 T 14-10-2018 A4R43_09760 2f3fc2ee517b54ba380798a3b7c2d5a0 496 Gene3D G3DSA:2.115.10.20 36 331 4.1E-87 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_26575 f50f8ef25f00e742f7d34ab5c8c09d46 163 SMART SM01058 2 112 8.9E-34 T 14-10-2018 IPR003711 CarD-like/TRCF domain A4R43_26575 f50f8ef25f00e742f7d34ab5c8c09d46 163 Pfam PF02559 CarD-like/TRCF domain 3 111 2.5E-18 T 14-10-2018 IPR003711 CarD-like/TRCF domain A4R43_26575 f50f8ef25f00e742f7d34ab5c8c09d46 163 Gene3D G3DSA:2.30.30.840 1 60 4.7E-26 T 14-10-2018 A4R43_26575 f50f8ef25f00e742f7d34ab5c8c09d46 163 Gene3D G3DSA:1.20.58.1290 61 162 2.3E-38 T 14-10-2018 A4R43_26575 f50f8ef25f00e742f7d34ab5c8c09d46 163 SUPERFAMILY SSF141259 3 65 3.79E-14 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily A4R43_07575 a98a0aa3add9e170f86137f7d3dae738 212 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 97 103 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4R43_07575 a98a0aa3add9e170f86137f7d3dae738 212 Pfam PF05175 Methyltransferase small domain 15 159 2.1E-13 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A4R43_07575 a98a0aa3add9e170f86137f7d3dae738 212 Gene3D G3DSA:3.40.50.150 2 188 3.1E-33 T 14-10-2018 A4R43_07575 a98a0aa3add9e170f86137f7d3dae738 212 SUPERFAMILY SSF53335 5 180 2.18E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 Pfam PF00005 ABC transporter 5 147 1.2E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 Gene3D G3DSA:3.40.50.300 224 459 1.3E-37 T 14-10-2018 A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 SUPERFAMILY SSF52540 3 199 8.56E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 SUPERFAMILY SSF52540 221 451 4.99E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 Pfam PF00005 ABC transporter 251 392 1.2E-10 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 ProSitePatterns PS00211 ABC transporters family signature. 365 379 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 Gene3D G3DSA:3.40.50.300 2 218 5.3E-52 T 14-10-2018 A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 SMART SM00382 13 195 1.3E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_35095 c3e8ccd8d83dbce94a5923410534d4f1 465 SMART SM00382 259 441 7.0 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_02665 120cf628a04f964651541e02826dfbf0 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 2.9E-23 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_02665 120cf628a04f964651541e02826dfbf0 328 Gene3D G3DSA:3.40.50.720 3 123 3.5E-29 T 14-10-2018 A4R43_02665 120cf628a04f964651541e02826dfbf0 328 SUPERFAMILY SSF51735 5 134 6.29E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_02665 120cf628a04f964651541e02826dfbf0 328 SUPERFAMILY SSF55347 146 248 2.29E-16 T 14-10-2018 A4R43_02665 120cf628a04f964651541e02826dfbf0 328 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 150 235 4.4E-10 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A4R43_02665 120cf628a04f964651541e02826dfbf0 328 Gene3D G3DSA:3.30.360.10 124 326 5.7E-30 T 14-10-2018 A4R43_37900 749bceb2ce5789653bbd60e673d2bd36 308 PIRSF PIRSF000707 1 308 8.9E-97 T 14-10-2018 IPR016259 Hygromycin-B kinase A4R43_37900 749bceb2ce5789653bbd60e673d2bd36 308 Pfam PF01636 Phosphotransferase enzyme family 46 263 3.0E-26 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_37900 749bceb2ce5789653bbd60e673d2bd36 308 SUPERFAMILY SSF56112 48 263 4.96E-27 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_37900 749bceb2ce5789653bbd60e673d2bd36 308 Gene3D G3DSA:3.90.1200.10 113 286 2.4E-12 T 14-10-2018 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 SUPERFAMILY SSF51064 119 170 1.22E-13 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 SUPERFAMILY SSF58014 21 114 1.57E-19 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 Pfam PF01025 GrpE 15 169 4.3E-36 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 Hamap MF_01151 Protein GrpE [grpE]. 3 170 15.728 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 Gene3D G3DSA:3.90.20.20 3 113 4.7E-25 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 Gene3D G3DSA:2.30.22.10 116 170 1.9E-15 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 ProSitePatterns PS01071 grpE protein signature. 125 168 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 PRINTS PR00773 GrpE protein signature 70 85 1.0E-17 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 PRINTS PR00773 GrpE protein signature 122 137 1.0E-17 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 PRINTS PR00773 GrpE protein signature 149 168 1.0E-17 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_29440 1b99418bedb94e6c99eacf512e985388 184 PRINTS PR00773 GrpE protein signature 42 58 1.0E-17 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4R43_26845 71dcd2096fa5eca9d676b4242325256d 182 Gene3D G3DSA:3.40.50.2020 1 181 1.2E-66 T 14-10-2018 A4R43_26845 71dcd2096fa5eca9d676b4242325256d 182 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 175 7.5E-67 T 14-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 A4R43_26845 71dcd2096fa5eca9d676b4242325256d 182 SUPERFAMILY SSF53271 2 180 2.49E-54 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_26845 71dcd2096fa5eca9d676b4242325256d 182 Pfam PF00156 Phosphoribosyl transferase domain 14 162 2.6E-22 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4R43_38240 1f801c18c2128658bc2cb9d74b56a05d 265 Gene3D G3DSA:1.10.1530.10 233 262 7.8E-8 T 14-10-2018 A4R43_38240 1f801c18c2128658bc2cb9d74b56a05d 265 Gene3D G3DSA:1.10.1530.10 13 71 3.8E-27 T 14-10-2018 A4R43_38240 1f801c18c2128658bc2cb9d74b56a05d 265 Gene3D G3DSA:3.30.1370.60 72 148 3.8E-27 T 14-10-2018 A4R43_38240 1f801c18c2128658bc2cb9d74b56a05d 265 Pfam PF02615 Malate/L-lactate dehydrogenase 12 148 2.5E-28 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 A4R43_38240 1f801c18c2128658bc2cb9d74b56a05d 265 Gene3D G3DSA:3.30.1370.60 173 232 7.8E-8 T 14-10-2018 A4R43_38240 1f801c18c2128658bc2cb9d74b56a05d 265 SUPERFAMILY SSF89733 10 261 2.88E-38 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 A4R43_39980 c2f352e01f561ace75eb42d600e51a1b 202 PIRSF PIRSF000368 1 166 4.2E-42 T 14-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 A4R43_39980 c2f352e01f561ace75eb42d600e51a1b 202 Pfam PF04055 Radical SAM superfamily 25 105 3.3E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_39980 c2f352e01f561ace75eb42d600e51a1b 202 Gene3D G3DSA:3.20.20.70 4 193 5.5E-32 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_39980 c2f352e01f561ace75eb42d600e51a1b 202 SUPERFAMILY SSF102114 24 103 7.32E-13 T 14-10-2018 A4R43_39980 c2f352e01f561ace75eb42d600e51a1b 202 Pfam PF13353 4Fe-4S single cluster domain 16 151 1.1E-31 T 14-10-2018 A4R43_18150 86252efe84d9cd57846b09da13693f4a 415 Pfam PF13796 Putative sensor 28 199 1.1E-27 T 14-10-2018 IPR025828 Putative sensor domain A4R43_18150 86252efe84d9cd57846b09da13693f4a 415 SUPERFAMILY SSF55874 302 414 4.02E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_18150 86252efe84d9cd57846b09da13693f4a 415 Pfam PF07730 Histidine kinase 227 295 6.0E-10 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_18150 86252efe84d9cd57846b09da13693f4a 415 Gene3D G3DSA:3.30.565.10 269 415 1.0E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_21115 445a483a6c1c473f3731f48f85e1c3bd 362 SUPERFAMILY SSF160631 19 155 1.31E-13 T 14-10-2018 A4R43_21115 445a483a6c1c473f3731f48f85e1c3bd 362 Gene3D G3DSA:3.40.1580.10 15 159 1.1E-8 T 14-10-2018 IPR037883 Knr4/Smi1-like domain superfamily A4R43_21115 445a483a6c1c473f3731f48f85e1c3bd 362 SMART SM00860 23 151 3.9E-9 T 14-10-2018 IPR018958 Knr4/Smi1-like domain A4R43_21115 445a483a6c1c473f3731f48f85e1c3bd 362 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 23 107 3.1E-8 T 14-10-2018 IPR018958 Knr4/Smi1-like domain A4R43_17110 fb41d03428d3848b493a496e3b0d50bc 198 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 129 1.7E-7 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_17110 fb41d03428d3848b493a496e3b0d50bc 198 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 22 182 2.0E-16 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_17110 fb41d03428d3848b493a496e3b0d50bc 198 SUPERFAMILY SSF109854 2 135 2.24E-14 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_17110 fb41d03428d3848b493a496e3b0d50bc 198 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 13 185 2.0E-33 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_16435 b2097e68ba03d2eefee4fcfcb879c6af 303 SUPERFAMILY SSF55174 10 62 1.53E-5 T 14-10-2018 A4R43_16435 b2097e68ba03d2eefee4fcfcb879c6af 303 Gene3D G3DSA:3.30.2350.10 77 303 8.1E-68 T 14-10-2018 A4R43_16435 b2097e68ba03d2eefee4fcfcb879c6af 303 SUPERFAMILY SSF55120 73 300 6.72E-70 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_16435 b2097e68ba03d2eefee4fcfcb879c6af 303 SMART SM00363 11 74 3.2E-4 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_16435 b2097e68ba03d2eefee4fcfcb879c6af 303 Pfam PF00849 RNA pseudouridylate synthase 84 238 1.4E-32 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_16435 b2097e68ba03d2eefee4fcfcb879c6af 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 9 300 2.5E-85 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_16435 b2097e68ba03d2eefee4fcfcb879c6af 303 Gene3D G3DSA:3.10.290.10 2 63 3.1E-8 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4R43_16435 b2097e68ba03d2eefee4fcfcb879c6af 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 130 144 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_08520 95d2ebcc15f7f775ba6108599aa06f80 106 SUPERFAMILY SSF54909 1 94 2.47E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_08520 95d2ebcc15f7f775ba6108599aa06f80 106 Pfam PF03795 YCII-related domain 1 89 3.8E-15 T 14-10-2018 IPR005545 YCII-related A4R43_08520 95d2ebcc15f7f775ba6108599aa06f80 106 Gene3D G3DSA:3.30.70.1060 1 104 7.9E-24 T 14-10-2018 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 Pfam PF01728 FtsJ-like methyltransferase 63 247 3.9E-20 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 Pfam PF01479 S4 domain 6 47 1.3E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 Gene3D G3DSA:3.40.50.150 65 269 3.0E-70 T 14-10-2018 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 SMART SM00363 5 71 2.9E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 SUPERFAMILY SSF55174 5 58 2.36E-11 T 14-10-2018 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 Gene3D G3DSA:3.10.290.10 1 64 1.6E-15 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 PIRSF PIRSF005578 1 266 1.5E-94 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 241 5.7E-58 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A4R43_14235 ed0a188f2af45d500e6860ec65492991 270 SUPERFAMILY SSF53335 61 248 2.41E-22 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 SUPERFAMILY SSF52518 370 533 1.05E-36 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 Gene3D G3DSA:3.40.50.970 370 538 3.0E-38 T 14-10-2018 A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 SUPERFAMILY SSF52467 166 349 6.35E-34 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 SUPERFAMILY SSF52518 2 188 1.63E-35 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 Gene3D G3DSA:3.40.50.970 1 185 3.6E-41 T 14-10-2018 A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 333 3.1E-28 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 Gene3D G3DSA:3.40.50.1220 200 369 1.2E-38 T 14-10-2018 A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 531 1.1E-27 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_13940 5d641e121b2cda1e80335deb500afea1 549 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 181 5.2E-40 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_22935 581259ff88bc8515e79b40c02db3940f 267 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 41 256 4.3E-25 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_22935 581259ff88bc8515e79b40c02db3940f 267 SUPERFAMILY SSF52266 37 255 8.33E-58 T 14-10-2018 A4R43_22935 581259ff88bc8515e79b40c02db3940f 267 Gene3D G3DSA:3.40.50.1110 35 265 9.1E-71 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_06015 f1bb7eeaffe37bbc6cea2e3baca5bac0 160 Gene3D G3DSA:3.40.140.10 7 160 3.0E-56 T 14-10-2018 A4R43_06015 f1bb7eeaffe37bbc6cea2e3baca5bac0 160 SUPERFAMILY SSF53927 10 143 6.02E-43 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_06015 f1bb7eeaffe37bbc6cea2e3baca5bac0 160 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 105 1.7E-23 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 Gene3D G3DSA:1.10.10.10 1 91 3.0E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 SMART SM00862 16 88 2.0E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 SMART SM01043 95 235 1.7E-43 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 PRINTS PR00364 Disease resistance protein signature 456 470 6.3E-5 T 14-10-2018 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 PRINTS PR00364 Disease resistance protein signature 350 364 6.3E-5 T 14-10-2018 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 PRINTS PR00364 Disease resistance protein signature 276 291 6.3E-5 T 14-10-2018 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 Gene3D G3DSA:1.25.40.10 738 1013 1.5E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 76 1.3E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 SUPERFAMILY SSF48452 787 904 7.59E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 Gene3D G3DSA:1.25.40.10 92 262 1.9E-43 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 SUPERFAMILY SSF46894 3 78 8.79E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 SUPERFAMILY SSF48452 90 241 2.69E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 Pfam PF03704 Bacterial transcriptional activator domain 95 235 1.0E-34 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03370 e0648042e985f4fef412f482b8359f43 1043 SUPERFAMILY SSF52540 249 523 2.76E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 Gene3D G3DSA:3.30.420.40 154 308 2.9E-81 T 14-10-2018 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 SUPERFAMILY SSF53067 4 146 1.36E-19 T 14-10-2018 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 PRINTS PR00301 70kDa heat shock protein signature 277 293 1.1E-5 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 PRINTS PR00301 70kDa heat shock protein signature 107 127 1.1E-5 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 PRINTS PR00301 70kDa heat shock protein signature 166 176 1.1E-5 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 PRINTS PR00301 70kDa heat shock protein signature 2 15 1.1E-5 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 Gene3D G3DSA:3.30.420.40 4 318 2.9E-81 T 14-10-2018 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 SUPERFAMILY SSF53067 155 319 2.2E-31 T 14-10-2018 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 Pfam PF00012 Hsp70 protein 106 318 2.7E-24 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 280 294 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_32345 fa0f0feb782fa3de0d57a41cf64e6824 534 Gene3D G3DSA:3.90.640.10 192 263 2.9E-81 T 14-10-2018 A4R43_22230 51d56258ae43771340e872d747fd3030 71 SMART SM00834 1 42 3.0E-12 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4R43_22230 51d56258ae43771340e872d747fd3030 71 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 49 9.8E-15 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4R43_22230 51d56258ae43771340e872d747fd3030 71 Pfam PF09723 Zinc ribbon domain 1 40 6.3E-12 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4R43_22840 debc23a176954c5d3de4de0521779cb3 373 SUPERFAMILY SSF53474 114 348 2.95E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22840 debc23a176954c5d3de4de0521779cb3 373 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 213 314 2.4E-5 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 A4R43_22840 debc23a176954c5d3de4de0521779cb3 373 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 110 163 2.4E-8 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 A4R43_22840 debc23a176954c5d3de4de0521779cb3 373 Gene3D G3DSA:3.40.50.1820 22 354 1.3E-66 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_28905 516225ea5e7aa49e6b2c40d4efd36aa8 340 Pfam PF05425 Copper resistance protein D 231 334 2.2E-20 T 14-10-2018 IPR008457 Copper resistance protein D GO:0016021 A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 Pfam PF07729 FCD domain 80 190 4.9E-18 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 Gene3D G3DSA:1.10.10.10 3 64 1.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 SUPERFAMILY SSF48008 71 200 7.06E-20 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 SMART SM00895 74 194 2.3E-8 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 8.0E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 8.0E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 Gene3D G3DSA:1.20.120.530 68 202 1.6E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 SMART SM00345 6 64 2.7E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 62 2.0E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06340 8ca774c96584b33ff2e6add76bdfb63f 203 SUPERFAMILY SSF46785 6 68 4.58E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_23210 4583fbea5259a137c323f029d69c8ac5 227 Gene3D G3DSA:3.30.505.50 180 225 8.2E-19 T 14-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily A4R43_23210 4583fbea5259a137c323f029d69c8ac5 227 SUPERFAMILY SSF69754 3 110 3.4E-26 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like A4R43_23210 4583fbea5259a137c323f029d69c8ac5 227 Gene3D G3DSA:3.30.160.100 3 103 3.5E-24 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like A4R43_23210 4583fbea5259a137c323f029d69c8ac5 227 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 169 222 2.2E-23 T 14-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal A4R43_23210 4583fbea5259a137c323f029d69c8ac5 227 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 1.5E-21 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 A4R43_23210 4583fbea5259a137c323f029d69c8ac5 227 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 3.7E-30 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 A4R43_23210 4583fbea5259a137c323f029d69c8ac5 227 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 226 23.728 T 14-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid A4R43_36850 7049a4604d036934932f1e6bead8d152 326 Pfam PF00296 Luciferase-like monooxygenase 18 297 2.0E-36 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_36850 7049a4604d036934932f1e6bead8d152 326 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 325 6.2E-101 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 A4R43_36850 7049a4604d036934932f1e6bead8d152 326 Gene3D G3DSA:3.20.20.30 3 326 5.9E-86 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_36850 7049a4604d036934932f1e6bead8d152 326 SUPERFAMILY SSF51679 4 325 1.83E-65 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_30730 4a9646fecf0e567314b7cf31a9ede6ff 474 Gene3D G3DSA:3.40.50.300 199 474 8.0E-99 T 14-10-2018 A4R43_30730 4a9646fecf0e567314b7cf31a9ede6ff 474 Pfam PF00772 DnaB-like helicase N terminal domain 35 137 3.0E-35 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A4R43_30730 4a9646fecf0e567314b7cf31a9ede6ff 474 SUPERFAMILY SSF52540 215 459 1.62E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30730 4a9646fecf0e567314b7cf31a9ede6ff 474 SUPERFAMILY SSF48024 34 145 1.44E-38 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 A4R43_30730 4a9646fecf0e567314b7cf31a9ede6ff 474 Pfam PF03796 DnaB-like helicase C terminal domain 216 470 4.4E-99 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A4R43_30730 4a9646fecf0e567314b7cf31a9ede6ff 474 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 36 472 2.4E-159 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A4R43_30730 4a9646fecf0e567314b7cf31a9ede6ff 474 Gene3D G3DSA:1.10.860.10 29 197 1.2E-60 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A4R43_30730 4a9646fecf0e567314b7cf31a9ede6ff 474 SMART SM00382 233 430 5.2E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_21550 ef3a89e264470cad04575ea77e3aad31 417 Gene3D G3DSA:3.50.50.60 4 319 7.6E-96 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21550 ef3a89e264470cad04575ea77e3aad31 417 Gene3D G3DSA:3.30.9.40 65 269 7.6E-96 T 14-10-2018 A4R43_21550 ef3a89e264470cad04575ea77e3aad31 417 SUPERFAMILY SSF51905 3 352 2.09E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21550 ef3a89e264470cad04575ea77e3aad31 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 2.6E-6 T 14-10-2018 A4R43_21550 ef3a89e264470cad04575ea77e3aad31 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.6E-6 T 14-10-2018 A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Gene3D G3DSA:3.90.650.10 597 764 6.5E-36 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 SUPERFAMILY SSF55326 422 591 2.22E-54 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Pfam PF00586 AIR synthase related protein, N-terminal domain 480 584 3.2E-22 T 14-10-2018 IPR016188 PurM-like, N-terminal domain A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Pfam PF00586 AIR synthase related protein, N-terminal domain 107 208 3.6E-22 T 14-10-2018 IPR016188 PurM-like, N-terminal domain A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Gene3D G3DSA:3.30.1330.10 59 213 6.5E-126 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 SUPERFAMILY SSF56042 221 451 1.64E-52 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 33 761 5.3E-255 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Gene3D G3DSA:3.30.1330.10 410 588 2.5E-54 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 SUPERFAMILY SSF55326 30 212 7.78E-49 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Gene3D G3DSA:3.90.650.10 45 387 6.5E-126 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Pfam PF02769 AIR synthase related protein, C-terminal domain 222 378 4.0E-34 T 14-10-2018 IPR010918 PurM-like, C-terminal domain A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Pfam PF02769 AIR synthase related protein, C-terminal domain 598 734 1.3E-18 T 14-10-2018 IPR010918 PurM-like, C-terminal domain A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 764 303.145 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 PIRSF PIRSF001587 9 764 1.2E-283 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4R43_31865 39495da36ac3556a6fdb16ef3d277aae 764 SUPERFAMILY SSF56042 597 763 2.39E-36 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4R43_07825 a5c3ec7a73037e6ac715e107ea19ea28 394 Pfam PF01266 FAD dependent oxidoreductase 5 363 2.8E-41 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_07825 a5c3ec7a73037e6ac715e107ea19ea28 394 SUPERFAMILY SSF54373 225 325 9.02E-20 T 14-10-2018 A4R43_07825 a5c3ec7a73037e6ac715e107ea19ea28 394 Gene3D G3DSA:3.30.9.10 88 323 5.5E-107 T 14-10-2018 A4R43_07825 a5c3ec7a73037e6ac715e107ea19ea28 394 Gene3D G3DSA:3.50.50.60 6 367 5.5E-107 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07825 a5c3ec7a73037e6ac715e107ea19ea28 394 SUPERFAMILY SSF51905 4 381 1.13E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_26300 2f19396c611bc94c2b6ae6f5974165a3 268 Gene3D G3DSA:1.10.10.2280 128 268 3.0E-51 T 14-10-2018 A4R43_26300 2f19396c611bc94c2b6ae6f5974165a3 268 Pfam PF14337 Domain of unknown function (DUF4393) 113 263 3.9E-12 T 14-10-2018 IPR025506 Protein of unknown function DUF4393 A4R43_23465 439a7346fe83f0b8a89cffd89e41aab0 387 Pfam PF00149 Calcineurin-like phosphoesterase 1 219 7.3E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_23465 439a7346fe83f0b8a89cffd89e41aab0 387 Gene3D G3DSA:3.60.21.10 1 268 1.9E-83 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_23465 439a7346fe83f0b8a89cffd89e41aab0 387 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 268 355 7.0E-8 T 14-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain A4R43_23465 439a7346fe83f0b8a89cffd89e41aab0 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 245 3.7E-48 T 14-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 A4R43_23465 439a7346fe83f0b8a89cffd89e41aab0 387 SUPERFAMILY SSF56300 1 316 2.85E-54 T 14-10-2018 A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 SUPERFAMILY SSF52540 436 663 1.98E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 SMART SM00382 825 1002 0.042 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 SMART SM00382 1112 1275 0.058 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 SMART SM00382 473 653 0.23 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 Gene3D G3DSA:3.40.50.300 764 1076 5.8E-86 T 14-10-2018 A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 Gene3D G3DSA:3.40.50.300 222 357 3.8E-7 T 14-10-2018 A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 696 5.0E-253 T 14-10-2018 IPR023836 EccCa-like, Actinobacteria A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 Pfam PF01580 FtsK/SpoIIIE family 1108 1188 2.7E-6 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 Pfam PF01580 FtsK/SpoIIIE family 806 1034 2.8E-49 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 Pfam PF01580 FtsK/SpoIIIE family 445 565 3.9E-24 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 SUPERFAMILY SSF52540 762 1006 1.2E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 SUPERFAMILY SSF52540 1091 1250 2.92E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 Gene3D G3DSA:3.40.50.300 1081 1319 2.4E-55 T 14-10-2018 A4R43_12265 43701f51024da01ac5e2d4db5b712f88 1324 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 745 1315 1.4E-225 T 14-10-2018 IPR023837 EccCb-like, Actinobacteria A4R43_39410 74ec4cbe5f5d7b536c8132320e0d22e4 155 Gene3D G3DSA:3.30.1310.10 3 108 1.2E-10 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_39410 74ec4cbe5f5d7b536c8132320e0d22e4 155 SUPERFAMILY SSF82607 10 95 1.03E-10 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_39410 74ec4cbe5f5d7b536c8132320e0d22e4 155 Pfam PF02575 YbaB/EbfC DNA-binding family 15 98 1.1E-12 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_39365 34b515e86ae4ff14e53dffba95dc8ffb 795 Gene3D G3DSA:3.60.15.10 539 785 1.4E-50 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_39365 34b515e86ae4ff14e53dffba95dc8ffb 795 Pfam PF03772 Competence protein 241 502 8.5E-52 T 14-10-2018 IPR004477 ComEC/Rec2-related protein A4R43_39365 34b515e86ae4ff14e53dffba95dc8ffb 795 SMART SM00849 548 748 2.6E-6 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_39365 34b515e86ae4ff14e53dffba95dc8ffb 795 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 263 432 1.2E-19 T 14-10-2018 IPR004477 ComEC/Rec2-related protein A4R43_39365 34b515e86ae4ff14e53dffba95dc8ffb 795 Pfam PF00753 Metallo-beta-lactamase superfamily 548 726 8.9E-8 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_39365 34b515e86ae4ff14e53dffba95dc8ffb 795 Pfam PF13567 Domain of unknown function (DUF4131) 37 190 1.2E-6 T 14-10-2018 IPR025405 Domain of unknown function DUF4131 A4R43_39365 34b515e86ae4ff14e53dffba95dc8ffb 795 SUPERFAMILY SSF56281 535 786 2.49E-34 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_40415 ff3a2b346371b2508750a8299f125266 133 Pfam PF14534 Domain of unknown function (DUF4440) 11 116 3.1E-12 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 A4R43_40415 ff3a2b346371b2508750a8299f125266 133 SUPERFAMILY SSF54427 4 123 9.13E-17 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_40415 ff3a2b346371b2508750a8299f125266 133 Gene3D G3DSA:3.10.450.50 4 124 8.7E-22 T 14-10-2018 A4R43_04595 74189c9a750733a0391ea8c555776a68 312 Gene3D G3DSA:1.10.630.10 1 310 1.5E-56 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04595 74189c9a750733a0391ea8c555776a68 312 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 245 254 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_04595 74189c9a750733a0391ea8c555776a68 312 PRINTS PR00359 B-class P450 signature 57 73 1.7E-23 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_04595 74189c9a750733a0391ea8c555776a68 312 PRINTS PR00359 B-class P450 signature 12 23 1.7E-23 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_04595 74189c9a750733a0391ea8c555776a68 312 PRINTS PR00359 B-class P450 signature 116 138 1.7E-23 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_04595 74189c9a750733a0391ea8c555776a68 312 PRINTS PR00359 B-class P450 signature 203 230 1.7E-23 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_04595 74189c9a750733a0391ea8c555776a68 312 PRINTS PR00359 B-class P450 signature 74 89 1.7E-23 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_04595 74189c9a750733a0391ea8c555776a68 312 SUPERFAMILY SSF48264 5 300 1.44E-41 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00170 e5cf88855405ce163ba073d03d973cf2 249 Gene3D G3DSA:3.40.50.720 2 245 8.8E-30 T 14-10-2018 A4R43_00170 e5cf88855405ce163ba073d03d973cf2 249 Pfam PF13460 NAD(P)H-binding 7 173 2.9E-11 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_00170 e5cf88855405ce163ba073d03d973cf2 249 SUPERFAMILY SSF51735 1 208 1.92E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_36515 ec5256594f5b66c24f13d36aa81c6864 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 6.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36515 ec5256594f5b66c24f13d36aa81c6864 191 Gene3D G3DSA:1.10.357.10 53 190 5.2E-15 T 14-10-2018 A4R43_36515 ec5256594f5b66c24f13d36aa81c6864 191 SUPERFAMILY SSF46689 4 64 2.19E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_36515 ec5256594f5b66c24f13d36aa81c6864 191 Gene3D G3DSA:1.10.10.60 2 52 1.5E-17 T 14-10-2018 A4R43_36515 ec5256594f5b66c24f13d36aa81c6864 191 Pfam PF13305 WHG domain 85 166 7.7E-7 T 14-10-2018 IPR025996 WHG domain A4R43_36515 ec5256594f5b66c24f13d36aa81c6864 191 SUPERFAMILY SSF48498 84 187 1.6E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_36515 ec5256594f5b66c24f13d36aa81c6864 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 6.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36515 ec5256594f5b66c24f13d36aa81c6864 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 6.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00740 ecb029127681c87d8c759e6c6796b706 375 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 31 167 2.0E-5 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 A4R43_00740 ecb029127681c87d8c759e6c6796b706 375 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 216 317 7.0E-7 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 A4R43_00740 ecb029127681c87d8c759e6c6796b706 375 Gene3D G3DSA:3.40.50.1820 25 354 4.4E-67 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00740 ecb029127681c87d8c759e6c6796b706 375 SUPERFAMILY SSF53474 60 358 1.58E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 SMART SM00387 332 439 1.1E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 SUPERFAMILY SSF47384 207 284 2.16E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 438 1.1E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 Gene3D G3DSA:3.30.565.10 287 436 1.3E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 1.5E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 436 1.5E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 1.5E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 SUPERFAMILY SSF55874 295 439 9.3E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30090 c4d0f370febcdbb719f9c1cb5cc46480 451 Gene3D G3DSA:1.10.287.130 230 286 1.3E-29 T 14-10-2018 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 Gene3D G3DSA:3.40.50.2300 157 287 2.9E-78 T 14-10-2018 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 SUPERFAMILY SSF47413 1 59 3.1E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 Gene3D G3DSA:3.40.50.2300 63 306 2.9E-78 T 14-10-2018 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 Gene3D G3DSA:1.10.260.40 1 59 2.5E-23 T 14-10-2018 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 SMART SM00354 1 71 6.5E-28 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 Pfam PF13377 Periplasmic binding protein-like domain 167 326 4.7E-36 T 14-10-2018 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.3E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.3E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 SUPERFAMILY SSF53822 62 326 7.07E-69 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 14-10-2018 A4R43_14625 dd66260e66a06ee9b094197348d0d1cb 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.3E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_05270 9f2ebc8554c41e21f47c469d588812db 374 PIRSF PIRSF001112 1 372 1.0E-116 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_05270 9f2ebc8554c41e21f47c469d588812db 374 PRINTS PR00412 Epoxide hydrolase signature 343 365 4.2E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_05270 9f2ebc8554c41e21f47c469d588812db 374 PRINTS PR00412 Epoxide hydrolase signature 179 192 4.2E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_05270 9f2ebc8554c41e21f47c469d588812db 374 PRINTS PR00412 Epoxide hydrolase signature 165 178 4.2E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_05270 9f2ebc8554c41e21f47c469d588812db 374 PRINTS PR00412 Epoxide hydrolase signature 101 119 4.2E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_05270 9f2ebc8554c41e21f47c469d588812db 374 SUPERFAMILY SSF53474 2 368 9.15E-106 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_05270 9f2ebc8554c41e21f47c469d588812db 374 Pfam PF06441 Epoxide hydrolase N terminus 5 110 7.6E-38 T 14-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 A4R43_05270 9f2ebc8554c41e21f47c469d588812db 374 Gene3D G3DSA:3.40.50.1820 5 373 1.6E-140 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40060 317c996bcc24d4a1db5e5e1ccd6ca572 319 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_40060 317c996bcc24d4a1db5e5e1ccd6ca572 319 Pfam PF08279 HTH domain 9 64 1.9E-14 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_40060 317c996bcc24d4a1db5e5e1ccd6ca572 319 Gene3D G3DSA:1.10.10.10 1 67 1.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40060 317c996bcc24d4a1db5e5e1ccd6ca572 319 Pfam PF13280 WYL domain 141 313 1.4E-22 T 14-10-2018 IPR026881 WYL domain A4R43_40060 317c996bcc24d4a1db5e5e1ccd6ca572 319 SUPERFAMILY SSF46785 6 63 1.89E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_36375 14ee21ebb7402f9804a571a501ddbf5e 257 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 238 6.8E-109 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A4R43_36375 14ee21ebb7402f9804a571a501ddbf5e 257 Gene3D G3DSA:3.30.230.70 15 250 8.7E-59 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_36375 14ee21ebb7402f9804a571a501ddbf5e 257 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site A4R43_36375 14ee21ebb7402f9804a571a501ddbf5e 257 SUPERFAMILY SSF54211 3 183 1.42E-42 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_36375 14ee21ebb7402f9804a571a501ddbf5e 257 Hamap MF_00564 Ribonuclease PH [rph]. 12 239 42.725 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A4R43_36375 14ee21ebb7402f9804a571a501ddbf5e 257 Pfam PF03725 3' exoribonuclease family, domain 2 160 225 3.4E-10 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_36375 14ee21ebb7402f9804a571a501ddbf5e 257 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 9.1E-22 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_36375 14ee21ebb7402f9804a571a501ddbf5e 257 SUPERFAMILY SSF55666 155 241 1.44E-22 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4R43_32450 abfba687eb127e3760899f0ecbedfe09 261 SMART SM00346 8 101 0.0035 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_32450 abfba687eb127e3760899f0ecbedfe09 261 SUPERFAMILY SSF46785 12 82 1.74E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_32450 abfba687eb127e3760899f0ecbedfe09 261 Pfam PF09339 IclR helix-turn-helix domain 12 65 5.7E-6 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_32450 abfba687eb127e3760899f0ecbedfe09 261 Gene3D G3DSA:3.30.450.40 85 260 1.4E-43 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_32450 abfba687eb127e3760899f0ecbedfe09 261 Pfam PF01614 Bacterial transcriptional regulator 136 252 5.0E-17 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_32450 abfba687eb127e3760899f0ecbedfe09 261 SUPERFAMILY SSF55781 70 258 1.24E-39 T 14-10-2018 A4R43_32450 abfba687eb127e3760899f0ecbedfe09 261 Gene3D G3DSA:1.10.10.10 10 84 2.4E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03050 c257bd2d89f304342839856309dd9f4d 320 Gene3D G3DSA:3.30.565.10 193 317 5.6E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03050 c257bd2d89f304342839856309dd9f4d 320 Pfam PF13581 Histidine kinase-like ATPase domain 197 309 5.1E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_03050 c257bd2d89f304342839856309dd9f4d 320 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 13 155 1.4E-33 T 14-10-2018 IPR025847 MEDS domain A4R43_17400 05fa2e3e966642aed44a3a799ce3b31c 519 SUPERFAMILY SSF53335 116 371 2.04E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_17400 05fa2e3e966642aed44a3a799ce3b31c 519 Pfam PF02384 N-6 DNA Methylase 116 304 8.0E-29 T 14-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4R43_17400 05fa2e3e966642aed44a3a799ce3b31c 519 Gene3D G3DSA:3.40.50.150 115 342 3.7E-40 T 14-10-2018 A4R43_17400 05fa2e3e966642aed44a3a799ce3b31c 519 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 154 168 1.6E-12 T 14-10-2018 A4R43_17400 05fa2e3e966642aed44a3a799ce3b31c 519 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 249 273 1.6E-12 T 14-10-2018 A4R43_17400 05fa2e3e966642aed44a3a799ce3b31c 519 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 215 227 1.6E-12 T 14-10-2018 A4R43_17400 05fa2e3e966642aed44a3a799ce3b31c 519 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 132 148 1.6E-12 T 14-10-2018 A4R43_24220 df9aa12a9f026d836bcee1bfcb4a8ce5 207 SUPERFAMILY SSF51735 1 205 6.05E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_24220 df9aa12a9f026d836bcee1bfcb4a8ce5 207 Gene3D G3DSA:3.40.50.720 1 207 1.7E-50 T 14-10-2018 A4R43_24220 df9aa12a9f026d836bcee1bfcb4a8ce5 207 Pfam PF13460 NAD(P)H-binding 7 195 4.7E-50 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_21205 fa8ab94ce731247026015220e2d92f8e 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 5.6E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21205 fa8ab94ce731247026015220e2d92f8e 187 SUPERFAMILY SSF46689 7 87 8.21E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21205 fa8ab94ce731247026015220e2d92f8e 187 Gene3D G3DSA:1.10.357.10 1 185 1.7E-42 T 14-10-2018 A4R43_33585 19cf2eccd41925349e62d8b1e6f1e2a5 183 SUPERFAMILY SSF160369 1 168 8.24E-49 T 14-10-2018 A4R43_33585 19cf2eccd41925349e62d8b1e6f1e2a5 183 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.316 T 14-10-2018 IPR022973 Ribosomal protein L10 A4R43_33585 19cf2eccd41925349e62d8b1e6f1e2a5 183 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 14-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33585 19cf2eccd41925349e62d8b1e6f1e2a5 183 Pfam PF00466 Ribosomal protein L10 1 98 6.5E-25 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A4R43_33585 19cf2eccd41925349e62d8b1e6f1e2a5 183 Gene3D G3DSA:3.30.70.1730 1 168 2.2E-36 T 14-10-2018 A4R43_25055 fadd7ffa85f5bda053fce86bc33944f8 230 Pfam PF00072 Response regulator receiver domain 3 112 4.2E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25055 fadd7ffa85f5bda053fce86bc33944f8 230 SMART SM00862 150 225 2.0E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25055 fadd7ffa85f5bda053fce86bc33944f8 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 4.3E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25055 fadd7ffa85f5bda053fce86bc33944f8 230 Gene3D G3DSA:3.40.50.2300 1 130 2.7E-41 T 14-10-2018 A4R43_25055 fadd7ffa85f5bda053fce86bc33944f8 230 SMART SM00448 1 112 8.0E-45 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25055 fadd7ffa85f5bda053fce86bc33944f8 230 SUPERFAMILY SSF52172 1 184 8.11E-44 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_25055 fadd7ffa85f5bda053fce86bc33944f8 230 Gene3D G3DSA:1.10.10.10 131 229 5.5E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02340 f2096b16a2004fc4cd22721ea71a4318 512 Gene3D G3DSA:3.50.50.60 24 390 3.4E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_02340 f2096b16a2004fc4cd22721ea71a4318 512 Gene3D G3DSA:3.30.9.10 119 352 3.4E-43 T 14-10-2018 A4R43_02340 f2096b16a2004fc4cd22721ea71a4318 512 Pfam PF01266 FAD dependent oxidoreductase 24 390 1.7E-28 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_02340 f2096b16a2004fc4cd22721ea71a4318 512 SUPERFAMILY SSF51905 22 403 1.29E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_24845 0bb15554229aaab1653e2b4a52285bac 650 Gene3D G3DSA:1.10.8.730 332 439 9.2E-76 T 14-10-2018 A4R43_24845 0bb15554229aaab1653e2b4a52285bac 650 Gene3D G3DSA:3.40.50.300 239 581 9.2E-76 T 14-10-2018 A4R43_24845 0bb15554229aaab1653e2b4a52285bac 650 SUPERFAMILY SSF52540 212 577 6.25E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24845 0bb15554229aaab1653e2b4a52285bac 650 Pfam PF01935 Domain of unknown function DUF87 254 319 1.1E-6 T 14-10-2018 IPR002789 Helicase HerA, central domain A4R43_28310 bf0f72a569d1afdb275050242ba36f10 379 Gene3D G3DSA:3.90.1150.10 257 377 9.1E-27 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_28310 bf0f72a569d1afdb275050242ba36f10 379 PIRSF PIRSF000390 4 378 2.8E-102 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_28310 bf0f72a569d1afdb275050242ba36f10 379 Gene3D G3DSA:3.40.640.10 1 256 1.5E-87 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_28310 bf0f72a569d1afdb275050242ba36f10 379 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 371 2.4E-105 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_28310 bf0f72a569d1afdb275050242ba36f10 379 SUPERFAMILY SSF53383 7 376 3.3E-102 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_10160 8a07fca33a213d36cccac45cfdaeec6c 295 PIRSF PIRSF001365 1 295 1.3E-57 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_10160 8a07fca33a213d36cccac45cfdaeec6c 295 Gene3D G3DSA:3.20.20.70 1 294 4.3E-78 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_10160 8a07fca33a213d36cccac45cfdaeec6c 295 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 5.8E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_10160 8a07fca33a213d36cccac45cfdaeec6c 295 SUPERFAMILY SSF51569 2 290 2.93E-63 T 14-10-2018 A4R43_10160 8a07fca33a213d36cccac45cfdaeec6c 295 SMART SM01130 1 292 1.5E-56 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_10160 8a07fca33a213d36cccac45cfdaeec6c 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 9.6E-9 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_10160 8a07fca33a213d36cccac45cfdaeec6c 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 9.6E-9 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_10160 8a07fca33a213d36cccac45cfdaeec6c 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 9.6E-9 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 Pfam PF03466 LysR substrate binding domain 90 287 4.4E-27 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 SUPERFAMILY SSF53850 94 287 2.78E-26 T 14-10-2018 A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 Gene3D G3DSA:1.10.10.10 4 89 3.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 SUPERFAMILY SSF46785 3 105 1.14E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 Gene3D G3DSA:3.40.190.10 90 286 2.5E-34 T 14-10-2018 A4R43_07165 9e8991b22e06a85ace5323f6441d0109 290 Gene3D G3DSA:3.40.190.10 164 268 2.5E-34 T 14-10-2018 A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 Pfam PF00005 ABC transporter 22 187 1.3E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 SUPERFAMILY SSF52540 5 229 4.74E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 Gene3D G3DSA:3.40.50.300 11 290 1.5E-55 T 14-10-2018 A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 SUPERFAMILY SSF52540 364 543 3.76E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 Pfam PF00005 ABC transporter 367 495 1.9E-16 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 Gene3D G3DSA:3.40.50.300 313 545 1.0E-40 T 14-10-2018 A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 SMART SM00382 29 232 3.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_11505 6b55d866311df2de8744c90a06ab2b7e 545 SMART SM00382 374 541 2.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_39075 ce666850e4d5012fc462a01bdf36eb1b 275 Gene3D G3DSA:3.40.140.10 132 275 1.8E-53 T 14-10-2018 A4R43_39075 ce666850e4d5012fc462a01bdf36eb1b 275 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 273 33.889 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4R43_39075 ce666850e4d5012fc462a01bdf36eb1b 275 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 1.2E-52 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4R43_39075 ce666850e4d5012fc462a01bdf36eb1b 275 Gene3D G3DSA:3.10.20.10 28 93 2.7E-6 T 14-10-2018 A4R43_39075 ce666850e4d5012fc462a01bdf36eb1b 275 PIRSF PIRSF015626 2 275 2.1E-87 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4R43_39075 ce666850e4d5012fc462a01bdf36eb1b 275 SUPERFAMILY SSF53927 5 272 5.41E-78 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_39075 ce666850e4d5012fc462a01bdf36eb1b 275 Pfam PF02634 FdhD/NarQ family 26 272 2.4E-82 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 Pfam PF07568 Histidine kinase 302 369 1.5E-22 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 Gene3D G3DSA:3.30.450.20 138 288 2.1E-39 T 14-10-2018 A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 Gene3D G3DSA:3.30.565.10 357 503 3.4E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 SUPERFAMILY SSF55874 357 500 1.26E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 Pfam PF08448 PAS fold 179 288 2.8E-8 T 14-10-2018 IPR013656 PAS fold-4 A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 Gene3D G3DSA:3.30.450.280 1 137 5.8E-43 T 14-10-2018 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 400 501 1.3E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 Pfam PF12282 Signal transduction histidine kinase 4 152 5.8E-53 T 14-10-2018 IPR022066 Signal transduction histidine kinase, N-terminal A4R43_23130 24ae06f0c00d13288b3169c015e9fc8d 504 SMART SM00387 396 502 8.1E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_37135 690478369563b752fd70f5b5b4c1fa40 535 Gene3D G3DSA:1.20.1720.10 21 263 9.2E-39 T 14-10-2018 A4R43_37135 690478369563b752fd70f5b5b4c1fa40 535 Pfam PF07690 Major Facilitator Superfamily 28 414 3.5E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_37135 690478369563b752fd70f5b5b4c1fa40 535 SUPERFAMILY SSF103473 13 504 1.57E-56 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_37135 690478369563b752fd70f5b5b4c1fa40 535 Gene3D G3DSA:1.20.1250.20 269 510 5.3E-9 T 14-10-2018 A4R43_37135 690478369563b752fd70f5b5b4c1fa40 535 PRINTS PR01035 Tetracycline resistance protein signature 146 168 7.9E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_37135 690478369563b752fd70f5b5b4c1fa40 535 PRINTS PR01035 Tetracycline resistance protein signature 343 366 7.9E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_37135 690478369563b752fd70f5b5b4c1fa40 535 PRINTS PR01035 Tetracycline resistance protein signature 33 49 7.9E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_37135 690478369563b752fd70f5b5b4c1fa40 535 PRINTS PR01035 Tetracycline resistance protein signature 63 82 7.9E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_16950 c4a5cd09ebc6d081a886285e5ec34e1f 207 Gene3D G3DSA:3.20.20.70 2 207 1.8E-74 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_16950 c4a5cd09ebc6d081a886285e5ec34e1f 207 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 205 4.4E-74 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4R43_16950 c4a5cd09ebc6d081a886285e5ec34e1f 207 Pfam PF01081 KDPG and KHG aldolase 8 199 2.4E-67 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4R43_16950 c4a5cd09ebc6d081a886285e5ec34e1f 207 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 14-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4R43_16950 c4a5cd09ebc6d081a886285e5ec34e1f 207 SUPERFAMILY SSF51569 5 205 8.06E-67 T 14-10-2018 A4R43_16950 c4a5cd09ebc6d081a886285e5ec34e1f 207 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 36 45 - T 14-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4R43_26155 3e20c8068ffbd62b74821fed3f3c64f3 278 Gene3D G3DSA:3.40.1190.20 1 277 6.7E-90 T 14-10-2018 IPR029056 Ribokinase-like A4R43_26155 3e20c8068ffbd62b74821fed3f3c64f3 278 Pfam PF08543 Phosphomethylpyrimidine kinase 17 266 7.9E-78 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A4R43_26155 3e20c8068ffbd62b74821fed3f3c64f3 278 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 10 268 1.8E-78 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4R43_26155 3e20c8068ffbd62b74821fed3f3c64f3 278 SUPERFAMILY SSF53613 8 273 3.74E-74 T 14-10-2018 IPR029056 Ribokinase-like A4R43_36690 d83e9e249b00ab89aa349b35b3305064 106 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 16 72 3.0E-5 T 14-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component A4R43_06930 e9e2ca6c12812f1cd68932ac43d3f04f 321 Gene3D G3DSA:2.115.10.20 27 320 1.7E-83 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_06930 e9e2ca6c12812f1cd68932ac43d3f04f 321 SUPERFAMILY SSF75005 31 319 3.0E-73 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_06930 e9e2ca6c12812f1cd68932ac43d3f04f 321 Pfam PF04616 Glycosyl hydrolases family 43 41 299 2.3E-46 T 14-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4R43_06930 e9e2ca6c12812f1cd68932ac43d3f04f 321 PIRSF PIRSF026534 6 321 3.3E-97 T 14-10-2018 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 A4R43_36840 27d5ce777b2faec23b0d22387dc00e53 132 Gene3D G3DSA:3.30.565.10 5 131 5.5E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_36840 27d5ce777b2faec23b0d22387dc00e53 132 Pfam PF13581 Histidine kinase-like ATPase domain 12 127 5.8E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_36840 27d5ce777b2faec23b0d22387dc00e53 132 SUPERFAMILY SSF55874 34 125 1.17E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_20040 1203702916222d93677c99a6a3571bad 500 SMART SM00845 352 499 8.4E-56 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A4R43_20040 1203702916222d93677c99a6a3571bad 500 Gene3D G3DSA:1.10.10.410 439 499 8.8E-16 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A4R43_20040 1203702916222d93677c99a6a3571bad 500 Gene3D G3DSA:1.10.150.380 322 437 5.7E-18 T 14-10-2018 A4R43_20040 1203702916222d93677c99a6a3571bad 500 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 497 3.1E-143 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A4R43_20040 1203702916222d93677c99a6a3571bad 500 SUPERFAMILY SSF89095 352 498 4.84E-25 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A4R43_20040 1203702916222d93677c99a6a3571bad 500 Pfam PF02637 GatB domain 353 498 3.0E-39 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A4R43_20040 1203702916222d93677c99a6a3571bad 500 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 16 500 35.644 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A4R43_20040 1203702916222d93677c99a6a3571bad 500 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 165 179 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A4R43_20040 1203702916222d93677c99a6a3571bad 500 SUPERFAMILY SSF55931 19 321 1.31E-112 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_20040 1203702916222d93677c99a6a3571bad 500 Pfam PF02934 GatB/GatE catalytic domain 20 314 1.4E-105 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A4R43_22665 a6a98653f27b88f16e9809c859481b39 248 Gene3D G3DSA:3.30.450.40 79 237 7.0E-35 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_22665 a6a98653f27b88f16e9809c859481b39 248 Pfam PF01614 Bacterial transcriptional regulator 125 240 1.0E-11 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_22665 a6a98653f27b88f16e9809c859481b39 248 Gene3D G3DSA:1.10.10.10 8 78 5.9E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22665 a6a98653f27b88f16e9809c859481b39 248 SUPERFAMILY SSF46785 11 79 7.79E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22665 a6a98653f27b88f16e9809c859481b39 248 SMART SM00346 9 98 8.7E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_22665 a6a98653f27b88f16e9809c859481b39 248 SUPERFAMILY SSF55781 83 242 4.19E-34 T 14-10-2018 A4R43_22665 a6a98653f27b88f16e9809c859481b39 248 Pfam PF09339 IclR helix-turn-helix domain 14 59 7.8E-9 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_02265 6255ec071fede5196532cd3efcd49168 296 Pfam PF00296 Luciferase-like monooxygenase 15 241 4.4E-40 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_02265 6255ec071fede5196532cd3efcd49168 296 Gene3D G3DSA:3.20.20.30 1 294 3.0E-55 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_02265 6255ec071fede5196532cd3efcd49168 296 SUPERFAMILY SSF51679 13 272 8.11E-48 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_41635 c1643bfe42b1f060bd63d93d94f2fb65 361 SUPERFAMILY SSF52518 6 358 1.25E-93 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_41635 c1643bfe42b1f060bd63d93d94f2fb65 361 Gene3D G3DSA:3.40.50.970 6 356 9.7E-107 T 14-10-2018 A4R43_41635 c1643bfe42b1f060bd63d93d94f2fb65 361 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 19 355 1.1E-124 T 14-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4R43_41635 c1643bfe42b1f060bd63d93d94f2fb65 361 Pfam PF00676 Dehydrogenase E1 component 46 317 1.5E-68 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A4R43_17025 8a824adf13b2d4d91387ac6cb8b1a539 322 Gene3D G3DSA:3.40.50.1100 52 148 2.4E-90 T 14-10-2018 A4R43_17025 8a824adf13b2d4d91387ac6cb8b1a539 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 304 4.2E-67 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_17025 8a824adf13b2d4d91387ac6cb8b1a539 322 Gene3D G3DSA:3.40.50.1100 16 307 2.4E-90 T 14-10-2018 A4R43_17025 8a824adf13b2d4d91387ac6cb8b1a539 322 SUPERFAMILY SSF53686 5 308 4.45E-75 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_20305 858767f35142fc9779537498b8d1d8e5 391 SUPERFAMILY SSF103473 6 377 1.57E-45 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_20305 858767f35142fc9779537498b8d1d8e5 391 Pfam PF07690 Major Facilitator Superfamily 16 342 5.9E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_20305 858767f35142fc9779537498b8d1d8e5 391 Gene3D G3DSA:1.20.1250.20 9 380 3.4E-39 T 14-10-2018 A4R43_23775 596e159dcd5d979cf57431c38298b7c4 137 SMART SM00422 1 69 6.4E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23775 596e159dcd5d979cf57431c38298b7c4 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 8.9E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23775 596e159dcd5d979cf57431c38298b7c4 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.9E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23775 596e159dcd5d979cf57431c38298b7c4 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.9E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23775 596e159dcd5d979cf57431c38298b7c4 137 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23775 596e159dcd5d979cf57431c38298b7c4 137 SUPERFAMILY SSF46955 1 115 4.76E-23 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_23775 596e159dcd5d979cf57431c38298b7c4 137 Gene3D G3DSA:1.10.1660.10 1 124 1.1E-24 T 14-10-2018 A4R43_23775 596e159dcd5d979cf57431c38298b7c4 137 Pfam PF13411 MerR HTH family regulatory protein 1 67 7.4E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 SUPERFAMILY SSF53474 3 307 1.8E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 PIRSF PIRSF006431 1 308 1.2E-106 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 3.4E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 3.4E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 3.4E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 34 42 1.3E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 59 70 1.3E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 107 121 1.3E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 Gene3D G3DSA:3.40.50.1820 1 308 7.8E-83 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 Pfam PF00561 alpha/beta hydrolase fold 35 292 4.3E-26 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22620 ccf5a4607f86434c2a5b70ab0e216e45 308 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 6 303 5.5E-88 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 A4R43_20645 27d84dbd1565cfe46c81df2915fad54d 298 Pfam PF13365 Trypsin-like peptidase domain 109 264 2.6E-35 T 14-10-2018 A4R43_20645 27d84dbd1565cfe46c81df2915fad54d 298 PRINTS PR00834 HtrA/DegQ protease family signature 140 160 2.7E-29 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_20645 27d84dbd1565cfe46c81df2915fad54d 298 PRINTS PR00834 HtrA/DegQ protease family signature 257 274 2.7E-29 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_20645 27d84dbd1565cfe46c81df2915fad54d 298 PRINTS PR00834 HtrA/DegQ protease family signature 118 130 2.7E-29 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_20645 27d84dbd1565cfe46c81df2915fad54d 298 PRINTS PR00834 HtrA/DegQ protease family signature 235 252 2.7E-29 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_20645 27d84dbd1565cfe46c81df2915fad54d 298 Gene3D G3DSA:2.40.10.10 171 298 1.1E-42 T 14-10-2018 A4R43_20645 27d84dbd1565cfe46c81df2915fad54d 298 SUPERFAMILY SSF50494 84 297 1.47E-57 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_20645 27d84dbd1565cfe46c81df2915fad54d 298 Gene3D G3DSA:2.40.10.10 77 170 6.8E-27 T 14-10-2018 A4R43_37115 cf72bd7b917842a921c0d336afafeb44 271 SUPERFAMILY SSF53335 5 270 1.12E-52 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_37115 cf72bd7b917842a921c0d336afafeb44 271 Gene3D G3DSA:3.40.50.150 1 270 2.1E-60 T 14-10-2018 A4R43_37115 cf72bd7b917842a921c0d336afafeb44 271 Pfam PF02353 Mycolic acid cyclopropane synthetase 8 242 1.7E-20 T 14-10-2018 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 SMART SM00387 359 470 2.3E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 SUPERFAMILY SSF47384 234 317 1.31E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 316 1.5E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 Pfam PF00672 HAMP domain 179 237 2.8E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 468 6.8E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 Gene3D G3DSA:1.10.287.130 183 317 5.4E-24 T 14-10-2018 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 SMART SM00304 179 241 6.6E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 SUPERFAMILY SSF55874 306 468 4.58E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 4.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 4.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 424 4.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 SMART SM00388 249 316 3.8E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_27460 c984a0efd10ed5ef00a8197a869f22d6 475 Gene3D G3DSA:3.30.565.10 329 470 3.9E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_02815 f348c403613fe66291b3d5480b6e56de 274 Pfam PF13649 Methyltransferase domain 43 140 1.4E-15 T 14-10-2018 A4R43_02815 f348c403613fe66291b3d5480b6e56de 274 SUPERFAMILY SSF53335 21 203 9.36E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_02815 f348c403613fe66291b3d5480b6e56de 274 Gene3D G3DSA:3.40.50.150 2 220 1.0E-31 T 14-10-2018 A4R43_18055 2a472f800aa2b18116002baa14ce803a 310 SMART SM00244 78 242 8.5E-9 T 14-10-2018 IPR001107 Band 7 domain A4R43_18055 2a472f800aa2b18116002baa14ce803a 310 Pfam PF01145 SPFH domain / Band 7 family 83 256 2.0E-22 T 14-10-2018 IPR001107 Band 7 domain A4R43_18055 2a472f800aa2b18116002baa14ce803a 310 Gene3D G3DSA:3.30.479.30 108 244 8.7E-10 T 14-10-2018 A4R43_18055 2a472f800aa2b18116002baa14ce803a 310 SUPERFAMILY SSF117892 112 244 7.32E-13 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily A4R43_28990 d2cd3bf9fbc0efadf62d20e29e4af235 284 Gene3D G3DSA:3.20.20.60 1 284 1.3E-95 T 14-10-2018 A4R43_28990 d2cd3bf9fbc0efadf62d20e29e4af235 284 PIRSF PIRSF015582 1 284 1.1E-83 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like A4R43_28990 d2cd3bf9fbc0efadf62d20e29e4af235 284 SUPERFAMILY SSF51621 2 227 4.28E-68 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_28990 d2cd3bf9fbc0efadf62d20e29e4af235 284 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 5 217 3.4E-46 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 1.2E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.2E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 SUPERFAMILY SSF55729 120 275 1.28E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 Pfam PF13420 Acetyltransferase (GNAT) domain 122 270 1.6E-12 T 14-10-2018 A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 Gene3D G3DSA:3.40.630.30 118 281 2.8E-38 T 14-10-2018 A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 SMART SM00418 21 107 1.9E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 Gene3D G3DSA:1.10.10.10 7 105 1.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 Pfam PF12840 Helix-turn-helix domain 21 80 1.2E-14 T 14-10-2018 A4R43_02975 2132662950eaa3430dadd0f3149fd161 284 SUPERFAMILY SSF46785 8 91 9.56E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00410 70cc7e063350b842b04caeabdab67006 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 19 435 1.6E-140 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A4R43_10875 ef83c290eefce24f961fbab1c08821ed 233 SUPERFAMILY SSF56784 19 205 2.63E-46 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_10875 ef83c290eefce24f961fbab1c08821ed 233 Gene3D G3DSA:3.40.50.1000 19 204 4.2E-50 T 14-10-2018 IPR023214 HAD superfamily A4R43_10875 ef83c290eefce24f961fbab1c08821ed 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 202 9.1E-15 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_10875 ef83c290eefce24f961fbab1c08821ed 233 Gene3D G3DSA:1.10.150.240 32 101 4.2E-50 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_10875 ef83c290eefce24f961fbab1c08821ed 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 20 202 2.4E-27 T 14-10-2018 A4R43_36530 ccbd31bf8f4ee15d6916078c24481482 302 SUPERFAMILY SSF56112 25 284 4.67E-28 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_36530 ccbd31bf8f4ee15d6916078c24481482 302 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 36 283 2.3E-67 T 14-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 A4R43_39335 e313116bae5a07a87a98aa7a7cebcf64 245 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 223 5.4E-10 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_39335 e313116bae5a07a87a98aa7a7cebcf64 245 SUPERFAMILY SSF52266 3 235 1.45E-14 T 14-10-2018 A4R43_18315 f652c19f5946c2efe48806e5273ba3e6 132 Gene3D G3DSA:3.30.720.120 6 77 8.1E-7 T 14-10-2018 A4R43_18315 f652c19f5946c2efe48806e5273ba3e6 132 SUPERFAMILY SSF54593 9 129 1.29E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_18315 f652c19f5946c2efe48806e5273ba3e6 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 126 3.8E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_18315 f652c19f5946c2efe48806e5273ba3e6 132 Gene3D G3DSA:3.30.720.110 78 131 1.9E-17 T 14-10-2018 A4R43_00190 202d2b4e16fcfbbc9767e3e9ee3d4615 657 SUPERFAMILY SSF51735 4 155 5.66E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_00190 202d2b4e16fcfbbc9767e3e9ee3d4615 657 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 127 7.8E-11 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_00190 202d2b4e16fcfbbc9767e3e9ee3d4615 657 Gene3D G3DSA:3.30.360.10 137 282 2.1E-21 T 14-10-2018 A4R43_00190 202d2b4e16fcfbbc9767e3e9ee3d4615 657 Gene3D G3DSA:3.40.50.720 2 136 3.4E-24 T 14-10-2018 A4R43_00190 202d2b4e16fcfbbc9767e3e9ee3d4615 657 SUPERFAMILY SSF55347 137 301 2.62E-12 T 14-10-2018 A4R43_00190 202d2b4e16fcfbbc9767e3e9ee3d4615 657 Pfam PF14100 Methane oxygenase PmoA 379 651 1.9E-60 T 14-10-2018 IPR029475 Methane oxygenase PmoA A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 Gene3D G3DSA:3.30.66.10 7 88 2.3E-32 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 Gene3D G3DSA:3.90.15.10 112 232 1.6E-66 T 14-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 SUPERFAMILY SSF55869 21 82 8.11E-21 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 80 274 2.2E-22 T 14-10-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 SUPERFAMILY SSF56349 77 313 1.57E-59 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 Gene3D G3DSA:1.10.132.120 89 319 1.6E-66 T 14-10-2018 A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 278 289 8.4E-8 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 144 158 8.4E-8 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 121 140 8.4E-8 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 A4R43_10275 c05ab40c43cf3abdaa7ef8a5ff5304ea 332 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 231 245 8.4E-8 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 A4R43_21030 60dfce1eba3989210f9d44aef54cee02 612 Pfam PF00501 AMP-binding enzyme 26 469 1.5E-89 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_21030 60dfce1eba3989210f9d44aef54cee02 612 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_21030 60dfce1eba3989210f9d44aef54cee02 612 SUPERFAMILY SSF56801 13 602 3.27E-117 T 14-10-2018 A4R43_21030 60dfce1eba3989210f9d44aef54cee02 612 Gene3D G3DSA:3.40.50.12780 323 466 4.9E-38 T 14-10-2018 A4R43_21030 60dfce1eba3989210f9d44aef54cee02 612 Gene3D G3DSA:3.40.50.12780 15 316 2.5E-53 T 14-10-2018 A4R43_31095 186e8cc0fd731579fae0efb4a9c3a0b5 284 SUPERFAMILY SSF54637 53 166 2.3E-12 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_31095 186e8cc0fd731579fae0efb4a9c3a0b5 284 SUPERFAMILY SSF54637 175 281 7.47E-25 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_31095 186e8cc0fd731579fae0efb4a9c3a0b5 284 Gene3D G3DSA:3.10.129.10 32 284 9.7E-84 T 14-10-2018 A4R43_31095 186e8cc0fd731579fae0efb4a9c3a0b5 284 Pfam PF01575 MaoC like domain 186 261 8.7E-15 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_35420 ce6c0b498f09f3de30a8e8d89d0b201f 295 Gene3D G3DSA:3.40.50.720 7 283 1.4E-91 T 14-10-2018 A4R43_35420 ce6c0b498f09f3de30a8e8d89d0b201f 295 Pfam PF04321 RmlD substrate binding domain 6 294 1.2E-102 T 14-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A4R43_35420 ce6c0b498f09f3de30a8e8d89d0b201f 295 Gene3D G3DSA:3.90.25.10 169 289 1.4E-91 T 14-10-2018 A4R43_35420 ce6c0b498f09f3de30a8e8d89d0b201f 295 SUPERFAMILY SSF51735 5 293 3.27E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_35420 ce6c0b498f09f3de30a8e8d89d0b201f 295 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 6 293 9.1E-85 T 14-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A4R43_32385 d7a89a1b6fce936ce562419c30d0f499 856 SUPERFAMILY SSF158745 515 841 1.14E-22 T 14-10-2018 A4R43_32385 d7a89a1b6fce936ce562419c30d0f499 856 SMART SM01260 521 845 2.7E-5 T 14-10-2018 IPR007822 Lanthionine synthetase C-like A4R43_32385 d7a89a1b6fce936ce562419c30d0f499 856 Gene3D G3DSA:3.30.200.20 218 311 2.8E-19 T 14-10-2018 A4R43_32385 d7a89a1b6fce936ce562419c30d0f499 856 Gene3D G3DSA:1.10.510.10 312 425 2.8E-19 T 14-10-2018 A4R43_32385 d7a89a1b6fce936ce562419c30d0f499 856 SMART SM00220 225 577 7.6E-5 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_32385 d7a89a1b6fce936ce562419c30d0f499 856 SUPERFAMILY SSF56112 225 430 6.88E-22 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_32385 d7a89a1b6fce936ce562419c30d0f499 856 Pfam PF00069 Protein kinase domain 236 407 4.8E-9 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_28520 479b2903a000f5d212803dd8ac21806a 496 PIRSF PIRSF006446 1 482 9.2E-137 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A4R43_28520 479b2903a000f5d212803dd8ac21806a 496 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 470 3.8E-166 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A4R43_16715 3d289e523d5285868a9a411dedb8f7b2 521 Pfam PF13598 Domain of unknown function (DUF4139) 203 511 1.1E-51 T 14-10-2018 IPR037291 Domain of unknown function DUF4139 A4R43_16715 3d289e523d5285868a9a411dedb8f7b2 521 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 12 107 2.3E-16 T 14-10-2018 IPR025554 Domain of unknown function DUF4140 A4R43_16715 3d289e523d5285868a9a411dedb8f7b2 521 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 9 515 4.3E-98 T 14-10-2018 IPR011935 Conserved hypothetical protein CHP02231 A4R43_32195 6367e3c5ad872ba65f08ad03ac6f22a8 138 SMART SM00347 24 123 3.3E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_32195 6367e3c5ad872ba65f08ad03ac6f22a8 138 Pfam PF12802 MarR family 31 89 5.3E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_32195 6367e3c5ad872ba65f08ad03ac6f22a8 138 Gene3D G3DSA:1.10.10.10 2 138 2.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32195 6367e3c5ad872ba65f08ad03ac6f22a8 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 3.7E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_32195 6367e3c5ad872ba65f08ad03ac6f22a8 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 3.7E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_32195 6367e3c5ad872ba65f08ad03ac6f22a8 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 3.7E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_32195 6367e3c5ad872ba65f08ad03ac6f22a8 138 SUPERFAMILY SSF46785 5 136 2.68E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_34975 dbbcd76bbfbf8c4859b0b7eb5221a359 330 SUPERFAMILY SSF52540 5 325 3.62E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34975 dbbcd76bbfbf8c4859b0b7eb5221a359 330 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 323 1.8E-115 T 14-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_34975 dbbcd76bbfbf8c4859b0b7eb5221a359 330 Gene3D G3DSA:1.20.5.170 2 50 5.9E-20 T 14-10-2018 A4R43_34975 dbbcd76bbfbf8c4859b0b7eb5221a359 330 Gene3D G3DSA:1.10.287.130 263 326 7.6E-24 T 14-10-2018 A4R43_34975 dbbcd76bbfbf8c4859b0b7eb5221a359 330 Pfam PF03308 ArgK protein 22 293 1.2E-112 T 14-10-2018 A4R43_34975 dbbcd76bbfbf8c4859b0b7eb5221a359 330 Gene3D G3DSA:3.40.50.300 51 261 3.8E-81 T 14-10-2018 A4R43_25965 b5e5c40ddb2d74c499685699c4ade9de 202 Pfam PF03029 Conserved hypothetical ATP binding protein 26 194 3.0E-26 T 14-10-2018 IPR004130 GPN-loop GTPase A4R43_25965 b5e5c40ddb2d74c499685699c4ade9de 202 SUPERFAMILY SSF52540 22 194 2.18E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25965 b5e5c40ddb2d74c499685699c4ade9de 202 Gene3D G3DSA:3.40.50.300 15 197 4.6E-16 T 14-10-2018 A4R43_40000 ef96d45d724f43f1f5edc8b4e070b02d 321 Pfam PF05035 2-keto-3-deoxy-galactonokinase 12 304 9.2E-85 T 14-10-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 A4R43_40000 ef96d45d724f43f1f5edc8b4e070b02d 321 Gene3D G3DSA:3.30.420.300 1 93 2.7E-22 T 14-10-2018 A4R43_40000 ef96d45d724f43f1f5edc8b4e070b02d 321 Gene3D G3DSA:3.30.420.310 94 309 1.1E-56 T 14-10-2018 A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 Gene3D G3DSA:1.10.260.40 1 56 8.8E-21 T 14-10-2018 A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 Pfam PF13377 Periplasmic binding protein-like domain 166 322 1.2E-28 T 14-10-2018 A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 SMART SM00354 1 69 2.3E-24 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 14-10-2018 A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 SUPERFAMILY SSF47413 1 56 3.44E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 Gene3D G3DSA:3.40.50.2300 60 315 1.5E-65 T 14-10-2018 A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 7.5E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 SUPERFAMILY SSF53822 59 322 9.21E-60 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_20495 77c5e7a19b96f4d5ebcae689d7876846 328 Gene3D G3DSA:3.40.50.2300 158 320 1.5E-65 T 14-10-2018 A4R43_07105 a26967bc526a5ae69648679548c043ac 958 Gene3D G3DSA:3.30.530.20 43 185 4.6E-7 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_07105 a26967bc526a5ae69648679548c043ac 958 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 44 182 8.8E-12 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_07105 a26967bc526a5ae69648679548c043ac 958 SUPERFAMILY SSF55961 47 183 6.05E-10 T 14-10-2018 A4R43_07105 a26967bc526a5ae69648679548c043ac 958 Gene3D G3DSA:1.10.12.10 901 958 1.7E-19 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_07105 a26967bc526a5ae69648679548c043ac 958 SUPERFAMILY SSF52096 706 958 4.21E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_07105 a26967bc526a5ae69648679548c043ac 958 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 799 819 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_07105 a26967bc526a5ae69648679548c043ac 958 Pfam PF00378 Enoyl-CoA hydratase/isomerase 714 957 6.5E-52 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_07105 a26967bc526a5ae69648679548c043ac 958 SUPERFAMILY SSF53901 486 601 9.75E-16 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07105 a26967bc526a5ae69648679548c043ac 958 SUPERFAMILY SSF53901 229 464 2.49E-9 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_07105 a26967bc526a5ae69648679548c043ac 958 Gene3D G3DSA:3.90.226.10 703 900 6.8E-64 T 14-10-2018 A4R43_15000 d96c83c4f5358df073084fd78e89e8ab 319 Pfam PF00877 NlpC/P60 family 208 306 4.5E-26 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_15000 d96c83c4f5358df073084fd78e89e8ab 319 SUPERFAMILY SSF54001 198 315 2.94E-36 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_15000 d96c83c4f5358df073084fd78e89e8ab 319 Gene3D G3DSA:3.90.1720.10 136 308 1.6E-43 T 14-10-2018 A4R43_37180 3b84d5d65c509f15b3309122593e22b9 324 Gene3D G3DSA:3.40.50.1100 52 155 9.8E-107 T 14-10-2018 A4R43_37180 3b84d5d65c509f15b3309122593e22b9 324 Gene3D G3DSA:3.40.50.1100 16 309 9.8E-107 T 14-10-2018 A4R43_37180 3b84d5d65c509f15b3309122593e22b9 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 302 2.3E-65 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_37180 3b84d5d65c509f15b3309122593e22b9 324 SUPERFAMILY SSF53686 12 312 7.46E-89 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_35515 5ebfc8892094e98465d7c58a20c2f3a1 361 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 5 361 5.6E-183 T 14-10-2018 IPR019880 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase OxyQ A4R43_35515 5ebfc8892094e98465d7c58a20c2f3a1 361 Pfam PF00155 Aminotransferase class I and II 27 360 1.1E-44 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_35515 5ebfc8892094e98465d7c58a20c2f3a1 361 SUPERFAMILY SSF53383 17 361 1.18E-81 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_35515 5ebfc8892094e98465d7c58a20c2f3a1 361 Gene3D G3DSA:3.40.640.10 39 267 5.8E-85 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_35515 5ebfc8892094e98465d7c58a20c2f3a1 361 Gene3D G3DSA:3.90.1150.10 11 354 5.8E-85 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_40880 2f6a10838282daa18d25bc1d42e43410 241 SUPERFAMILY SSF55729 37 230 4.53E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_40880 2f6a10838282daa18d25bc1d42e43410 241 Gene3D G3DSA:3.40.630.30 3 238 4.2E-30 T 14-10-2018 A4R43_16250 d3651eda0e2f9785fa82904b435a78d6 200 SUPERFAMILY SSF46689 7 88 4.41E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_16250 d3651eda0e2f9785fa82904b435a78d6 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.6E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16250 d3651eda0e2f9785fa82904b435a78d6 200 Gene3D G3DSA:1.10.357.10 4 194 1.0E-31 T 14-10-2018 A4R43_16250 d3651eda0e2f9785fa82904b435a78d6 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16250 d3651eda0e2f9785fa82904b435a78d6 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_12465 57faf32f9e7ff9b7cf8c2f12fc5f9c16 312 SUPERFAMILY SSF54427 194 280 5.12E-6 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_12465 57faf32f9e7ff9b7cf8c2f12fc5f9c16 312 SUPERFAMILY SSF54427 32 156 5.93E-12 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_12465 57faf32f9e7ff9b7cf8c2f12fc5f9c16 312 Pfam PF12680 SnoaL-like domain 32 133 3.0E-6 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_12465 57faf32f9e7ff9b7cf8c2f12fc5f9c16 312 Gene3D G3DSA:3.10.450.50 23 159 1.1E-10 T 14-10-2018 A4R43_07700 df320c63cf391fdda38ca065987521c3 195 Gene3D G3DSA:1.10.357.10 12 195 2.3E-47 T 14-10-2018 A4R43_07700 df320c63cf391fdda38ca065987521c3 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07700 df320c63cf391fdda38ca065987521c3 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07700 df320c63cf391fdda38ca065987521c3 195 SUPERFAMILY SSF46689 7 84 1.8E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_07700 df320c63cf391fdda38ca065987521c3 195 SUPERFAMILY SSF48498 80 193 7.41E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_07700 df320c63cf391fdda38ca065987521c3 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.0E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40755 c9766e31304fe49130cba72a444bfbb1 476 Gene3D G3DSA:3.40.50.12780 13 373 1.1E-61 T 14-10-2018 A4R43_40755 c9766e31304fe49130cba72a444bfbb1 476 Gene3D G3DSA:3.30.300.310 374 475 2.8E-25 T 14-10-2018 A4R43_40755 c9766e31304fe49130cba72a444bfbb1 476 SUPERFAMILY SSF56801 31 473 3.01E-98 T 14-10-2018 A4R43_40755 c9766e31304fe49130cba72a444bfbb1 476 Pfam PF13193 AMP-binding enzyme C-terminal domain 387 462 1.6E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_40755 c9766e31304fe49130cba72a444bfbb1 476 Pfam PF00501 AMP-binding enzyme 39 136 5.9E-14 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_40755 c9766e31304fe49130cba72a444bfbb1 476 Pfam PF00501 AMP-binding enzyme 148 378 5.3E-26 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_25415 5e0bb317ce68304811f7d2d06c652d6b 362 SUPERFAMILY SSF50129 2 186 2.51E-51 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_25415 5e0bb317ce68304811f7d2d06c652d6b 362 SUPERFAMILY SSF51735 151 327 1.37E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_25415 5e0bb317ce68304811f7d2d06c652d6b 362 Gene3D G3DSA:3.40.50.720 167 303 1.9E-108 T 14-10-2018 A4R43_25415 5e0bb317ce68304811f7d2d06c652d6b 362 SMART SM00829 15 358 2.4E-7 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_25415 5e0bb317ce68304811f7d2d06c652d6b 362 Gene3D G3DSA:3.90.180.10 7 353 1.9E-108 T 14-10-2018 A4R43_25415 5e0bb317ce68304811f7d2d06c652d6b 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_25415 5e0bb317ce68304811f7d2d06c652d6b 362 Pfam PF00107 Zinc-binding dehydrogenase 190 309 1.3E-26 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_25415 5e0bb317ce68304811f7d2d06c652d6b 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 144 4.6E-25 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 381 7.4E-121 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 Pfam PF00108 Thiolase, N-terminal domain 5 252 6.1E-56 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 SUPERFAMILY SSF53901 261 382 3.27E-41 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 PIRSF PIRSF000429 1 383 1.4E-117 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 Gene3D G3DSA:3.40.47.10 6 266 2.7E-132 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 ProSitePatterns PS00737 Thiolases signature 2. 329 345 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 SUPERFAMILY SSF53901 4 260 6.01E-66 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 Pfam PF02803 Thiolase, C-terminal domain 260 382 3.7E-41 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_15980 9cd39307e1598bbe8ec4cfb0e3dd92d9 383 Gene3D G3DSA:3.40.47.10 127 379 2.7E-132 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_21305 1514d06a8e14db3937869065990cc5db 443 Gene3D G3DSA:1.20.1250.20 15 431 2.0E-44 T 14-10-2018 A4R43_21305 1514d06a8e14db3937869065990cc5db 443 Pfam PF00083 Sugar (and other) transporter 20 216 4.1E-19 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_21305 1514d06a8e14db3937869065990cc5db 443 SUPERFAMILY SSF103473 15 424 1.12E-50 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_22050 072eb661a1f93de2623548f35dbdc1ba 346 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 230 341 3.2E-11 T 14-10-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain A4R43_22050 072eb661a1f93de2623548f35dbdc1ba 346 Gene3D G3DSA:3.40.50.720 171 341 4.8E-24 T 14-10-2018 A4R43_22050 072eb661a1f93de2623548f35dbdc1ba 346 SUPERFAMILY SSF69572 126 337 5.36E-10 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A4R43_22050 072eb661a1f93de2623548f35dbdc1ba 346 Pfam PF00899 ThiF family 126 339 6.2E-8 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 Gene3D G3DSA:3.30.379.10 45 177 1.4E-177 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 SUPERFAMILY SSF51055 535 587 4.9E-15 T 14-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 SUPERFAMILY SSF55545 34 177 3.14E-25 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 SMART SM00495 539 584 5.2E-17 T 14-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 SUPERFAMILY SSF51445 178 522 2.62E-109 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 351 493 3.1E-25 T 14-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 178 344 6.9E-60 T 14-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 44 174 1.1E-17 T 14-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 Gene3D G3DSA:2.10.10.20 538 582 3.1E-18 T 14-10-2018 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 PRINTS PR00738 Glycosyl hydrolase family 20 signature 201 222 2.7E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 PRINTS PR00738 Glycosyl hydrolase family 20 signature 475 492 2.7E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 PRINTS PR00738 Glycosyl hydrolase family 20 signature 260 277 2.7E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 PRINTS PR00738 Glycosyl hydrolase family 20 signature 457 473 2.7E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 PRINTS PR00738 Glycosyl hydrolase family 20 signature 308 326 2.7E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 PRINTS PR00738 Glycosyl hydrolase family 20 signature 130 150 2.7E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 PRINTS PR00738 Glycosyl hydrolase family 20 signature 172 189 2.7E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 PRINTS PR00738 Glycosyl hydrolase family 20 signature 330 343 2.7E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_39435 3fe254e38fc3708a7dc43467e86b7887 587 Gene3D G3DSA:3.20.20.80 178 517 1.4E-177 T 14-10-2018 A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 Gene3D G3DSA:3.30.70.2740 388 470 2.0E-7 T 14-10-2018 A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 Pfam PF13183 4Fe-4S dicluster domain 532 605 2.5E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 Gene3D G3DSA:1.10.1060.10 513 625 2.6E-6 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 SUPERFAMILY SSF46548 486 617 8.89E-18 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 Gene3D G3DSA:3.30.465.40 7 191 1.3E-31 T 14-10-2018 A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 535 546 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 Pfam PF02913 FAD linked oxidases, C-terminal domain 263 508 3.8E-50 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 Pfam PF02754 Cysteine-rich domain 824 904 9.6E-4 T 14-10-2018 IPR004017 Cysteine-rich domain A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 SUPERFAMILY SSF55103 235 515 8.83E-48 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 SUPERFAMILY SSF56176 11 260 4.39E-51 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_01715 e1086a1ee6056481518a29a928f71f24 930 Pfam PF01565 FAD binding domain 36 172 5.0E-33 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_05070 ec9b4a5377966f4e09781cc06ba59a74 133 Pfam PF01883 Iron-sulfur cluster assembly protein 33 97 1.8E-18 T 14-10-2018 IPR002744 MIP18 family-like A4R43_05070 ec9b4a5377966f4e09781cc06ba59a74 133 SUPERFAMILY SSF117916 32 127 9.81E-27 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4R43_05070 ec9b4a5377966f4e09781cc06ba59a74 133 Gene3D G3DSA:3.30.300.130 26 128 1.2E-30 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4R43_32660 ad758a7a9082c7cea35768f08fa2260c 125 SUPERFAMILY SSF54593 6 124 2.48E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_32660 ad758a7a9082c7cea35768f08fa2260c 125 Gene3D G3DSA:3.10.180.10 4 125 5.7E-30 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_15085 9a321532a76d70f20bd4d05868e16ea9 285 Pfam PF13359 DDE superfamily endonuclease 131 278 3.5E-23 T 14-10-2018 IPR027806 Harbinger transposase-derived nuclease domain A4R43_37970 d4892d594ef0b922027c33c6121d7074 266 Gene3D G3DSA:3.20.20.30 128 266 3.0E-11 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_37970 d4892d594ef0b922027c33c6121d7074 266 Pfam PF00296 Luciferase-like monooxygenase 9 120 5.2E-19 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_37970 d4892d594ef0b922027c33c6121d7074 266 Pfam PF00296 Luciferase-like monooxygenase 134 213 5.4E-6 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_37970 d4892d594ef0b922027c33c6121d7074 266 Gene3D G3DSA:3.20.20.30 1 127 1.9E-25 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_37970 d4892d594ef0b922027c33c6121d7074 266 SUPERFAMILY SSF51679 1 265 3.24E-40 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_14480 c12108e50e4def721881edbb053760b0 151 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 14 50 7.4E-5 T 14-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 A4R43_14480 c12108e50e4def721881edbb053760b0 151 SUPERFAMILY SSF55961 7 146 3.9E-15 T 14-10-2018 A4R43_14480 c12108e50e4def721881edbb053760b0 151 Gene3D G3DSA:3.30.530.20 4 147 1.2E-12 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_20640 a07911fefef89d5804e4cfda974cc233 442 SUPERFAMILY SSF55031 206 314 2.22E-23 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_20640 a07911fefef89d5804e4cfda974cc233 442 PIRSF PIRSF037226 41 435 1.2E-124 T 14-10-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted A4R43_20640 a07911fefef89d5804e4cfda974cc233 442 Gene3D G3DSA:3.30.70.360 206 324 9.3E-122 T 14-10-2018 A4R43_20640 a07911fefef89d5804e4cfda974cc233 442 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 61 387 1.1E-73 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 A4R43_20640 a07911fefef89d5804e4cfda974cc233 442 Pfam PF07687 Peptidase dimerisation domain 209 298 1.4E-9 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_20640 a07911fefef89d5804e4cfda974cc233 442 Gene3D G3DSA:3.40.630.10 62 404 9.3E-122 T 14-10-2018 A4R43_20640 a07911fefef89d5804e4cfda974cc233 442 SUPERFAMILY SSF53187 51 419 1.14E-55 T 14-10-2018 A4R43_17390 f8f26e17f48c7a752b02b93d2cc31b6c 366 Gene3D G3DSA:3.60.21.10 96 326 1.4E-12 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_17390 f8f26e17f48c7a752b02b93d2cc31b6c 366 SMART SM00854 41 285 6.0E-82 T 14-10-2018 IPR019079 Capsule synthesis protein, CapA A4R43_17390 f8f26e17f48c7a752b02b93d2cc31b6c 366 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 42 283 8.7E-70 T 14-10-2018 IPR019079 Capsule synthesis protein, CapA A4R43_17390 f8f26e17f48c7a752b02b93d2cc31b6c 366 SUPERFAMILY SSF56300 41 324 1.19E-35 T 14-10-2018 A4R43_27910 d763753a631c2b3306c82d75cf5e8cfd 165 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 161 9.8E-58 T 14-10-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 2.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 SUPERFAMILY SSF46894 137 207 2.01E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 SUPERFAMILY SSF52172 1 128 3.98E-29 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 Gene3D G3DSA:3.40.50.12740 2 208 5.0E-60 T 14-10-2018 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 Pfam PF00072 Response regulator receiver domain 4 115 5.0E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 SMART SM00421 147 204 1.2E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20190 c3a92bebb6317cfd62523ebb116f2bdf 212 SMART SM00448 2 115 2.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 SMART SM00895 99 221 3.2E-23 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 SMART SM00345 18 77 1.3E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.6E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 SUPERFAMILY SSF46785 8 81 5.45E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 Gene3D G3DSA:1.20.120.530 96 229 1.8E-32 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 Pfam PF07729 FCD domain 99 220 4.7E-29 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 Gene3D G3DSA:1.10.10.10 4 77 1.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34245 ac9ebd8fe5a7e2959c51344b80479b58 236 SUPERFAMILY SSF48008 97 224 2.43E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_31830 45bd2bab888fff067b01c2abdbe27c3a 498 Gene3D G3DSA:3.40.605.10 14 461 5.7E-145 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_31830 45bd2bab888fff067b01c2abdbe27c3a 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_31830 45bd2bab888fff067b01c2abdbe27c3a 498 SUPERFAMILY SSF53720 9 468 2.62E-137 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_31830 45bd2bab888fff067b01c2abdbe27c3a 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_31830 45bd2bab888fff067b01c2abdbe27c3a 498 PIRSF PIRSF036492 11 498 3.5E-100 T 14-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 A4R43_31830 45bd2bab888fff067b01c2abdbe27c3a 498 Gene3D G3DSA:3.40.309.10 246 432 5.7E-145 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_31830 45bd2bab888fff067b01c2abdbe27c3a 498 Pfam PF00171 Aldehyde dehydrogenase family 11 463 7.4E-134 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_01410 a8446357f121b9dc403221d4f5bd6fd5 321 SUPERFAMILY SSF140453 82 173 8.5E-7 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_29095 e0fffd8a49e759d6807cc82183596415 154 SUPERFAMILY SSF49879 40 153 5.36E-25 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 A4R43_29095 e0fffd8a49e759d6807cc82183596415 154 SMART SM00240 81 131 5.4E-13 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4R43_29095 e0fffd8a49e759d6807cc82183596415 154 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 65 153 2.6E-15 T 14-10-2018 IPR032030 YscD, cytoplasmic domain A4R43_29095 e0fffd8a49e759d6807cc82183596415 154 Gene3D G3DSA:2.60.200.20 41 153 1.5E-25 T 14-10-2018 A4R43_02220 2263cea9487f4faed1add1bbd0778266 304 SUPERFAMILY SSF51197 19 296 3.3E-45 T 14-10-2018 A4R43_02220 2263cea9487f4faed1add1bbd0778266 304 Gene3D G3DSA:2.60.120.620 15 299 4.0E-90 T 14-10-2018 A4R43_02220 2263cea9487f4faed1add1bbd0778266 304 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 66 237 1.1E-25 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase A4R43_14630 a36c850606d8a378ced90e752113e44c 332 SUPERFAMILY SSF53822 45 325 8.75E-68 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_14630 a36c850606d8a378ced90e752113e44c 332 Pfam PF13407 Periplasmic binding protein domain 48 299 2.8E-47 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_14630 a36c850606d8a378ced90e752113e44c 332 Gene3D G3DSA:3.40.50.2300 57 299 8.9E-85 T 14-10-2018 A4R43_14630 a36c850606d8a378ced90e752113e44c 332 Gene3D G3DSA:3.40.50.2300 150 286 8.9E-85 T 14-10-2018 A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 225 323 1.0E-29 T 14-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 Pfam PF02390 Putative methyltransferase 246 307 3.6E-6 T 14-10-2018 A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 Gene3D G3DSA:3.40.50.150 211 389 1.7E-63 T 14-10-2018 A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 Gene3D G3DSA:3.40.1010.10 1 101 5.7E-17 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 5 187 6.2E-39 T 14-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 PIRSF PIRSF036428 1 389 7.4E-126 T 14-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 SUPERFAMILY SSF53335 210 380 1.04E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 SUPERFAMILY SSF53790 3 202 7.71E-33 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4R43_41535 4a862efa1a9cfc8e1d66f6ccb3bab1ba 389 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 185 4.2E-16 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4R43_08915 a9f718e1e1b2b0576cafb6415fad7243 177 SUPERFAMILY SSF48498 76 176 3.62E-14 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_08915 a9f718e1e1b2b0576cafb6415fad7243 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 9.8E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08915 a9f718e1e1b2b0576cafb6415fad7243 177 Gene3D G3DSA:1.10.357.10 1 177 2.2E-48 T 14-10-2018 A4R43_08915 a9f718e1e1b2b0576cafb6415fad7243 177 SUPERFAMILY SSF46689 2 77 2.74E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08915 a9f718e1e1b2b0576cafb6415fad7243 177 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08915 a9f718e1e1b2b0576cafb6415fad7243 177 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 5.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 Gene3D G3DSA:3.40.190.10 161 266 7.7E-19 T 14-10-2018 A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 2.1E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 Pfam PF03466 LysR substrate binding domain 103 291 3.3E-16 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 SUPERFAMILY SSF46785 4 86 1.36E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 Gene3D G3DSA:3.40.190.10 104 285 7.7E-19 T 14-10-2018 A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 SUPERFAMILY SSF53850 103 294 7.48E-19 T 14-10-2018 A4R43_40590 11c81c9a228678b2b7bb717dd76b6748 308 Gene3D G3DSA:1.10.10.10 4 89 1.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02710 213346aa15041401ff8ea317e67871cd 512 Pfam PF01235 Sodium:alanine symporter family 87 507 6.7E-126 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4R43_02710 213346aa15041401ff8ea317e67871cd 512 PRINTS PR00175 Sodium/alanine symporter signature 468 488 6.6E-41 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4R43_02710 213346aa15041401ff8ea317e67871cd 512 PRINTS PR00175 Sodium/alanine symporter signature 262 281 6.6E-41 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4R43_02710 213346aa15041401ff8ea317e67871cd 512 PRINTS PR00175 Sodium/alanine symporter signature 352 370 6.6E-41 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4R43_02710 213346aa15041401ff8ea317e67871cd 512 PRINTS PR00175 Sodium/alanine symporter signature 407 429 6.6E-41 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4R43_02710 213346aa15041401ff8ea317e67871cd 512 PRINTS PR00175 Sodium/alanine symporter signature 234 252 6.6E-41 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4R43_02710 213346aa15041401ff8ea317e67871cd 512 PRINTS PR00175 Sodium/alanine symporter signature 123 145 6.6E-41 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4R43_02710 213346aa15041401ff8ea317e67871cd 512 TIGRFAM TIGR00835 agcS: amino acid carrier protein 51 499 6.6E-108 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4R43_06160 e3f4d95118007bf12a10680aecce1e51 137 Gene3D G3DSA:1.10.10.10 4 125 1.0E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06160 e3f4d95118007bf12a10680aecce1e51 137 SUPERFAMILY SSF46785 11 124 1.04E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06160 e3f4d95118007bf12a10680aecce1e51 137 Pfam PF01638 HxlR-like helix-turn-helix 18 119 4.6E-9 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_07860 e3536bbe65f29915216927382fd1305b 328 Pfam PF00294 pfkB family carbohydrate kinase 61 318 1.5E-52 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_07860 e3536bbe65f29915216927382fd1305b 328 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 275 288 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_07860 e3536bbe65f29915216927382fd1305b 328 Gene3D G3DSA:3.30.1110.10 18 134 1.2E-88 T 14-10-2018 A4R43_07860 e3536bbe65f29915216927382fd1305b 328 Gene3D G3DSA:3.40.1190.20 15 316 1.2E-88 T 14-10-2018 IPR029056 Ribokinase-like A4R43_07860 e3536bbe65f29915216927382fd1305b 328 SUPERFAMILY SSF53613 8 320 2.49E-78 T 14-10-2018 IPR029056 Ribokinase-like A4R43_28245 175c6f13bae1f6e3a40150b80e45bc69 356 SUPERFAMILY SSF56059 112 318 3.16E-17 T 14-10-2018 A4R43_28245 175c6f13bae1f6e3a40150b80e45bc69 356 Gene3D G3DSA:3.40.50.20 1 101 2.6E-13 T 14-10-2018 A4R43_28245 175c6f13bae1f6e3a40150b80e45bc69 356 Gene3D G3DSA:3.30.470.20 105 341 3.9E-16 T 14-10-2018 A4R43_34235 ef9d77a3dccd3f462b492bfd57280594 478 Pfam PF13193 AMP-binding enzyme C-terminal domain 396 470 4.7E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_34235 ef9d77a3dccd3f462b492bfd57280594 478 ProSitePatterns PS00455 Putative AMP-binding domain signature. 137 148 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_34235 ef9d77a3dccd3f462b492bfd57280594 478 Gene3D G3DSA:3.30.300.310 383 478 1.7E-30 T 14-10-2018 A4R43_34235 ef9d77a3dccd3f462b492bfd57280594 478 Gene3D G3DSA:3.40.50.12780 5 381 2.5E-129 T 14-10-2018 A4R43_34235 ef9d77a3dccd3f462b492bfd57280594 478 SUPERFAMILY SSF56801 8 476 1.7E-127 T 14-10-2018 A4R43_34235 ef9d77a3dccd3f462b492bfd57280594 478 Pfam PF00501 AMP-binding enzyme 11 386 2.3E-85 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_24950 4edde8f9af1c1c5048509bbf8e40ac0f 301 SUPERFAMILY SSF53448 11 290 1.69E-57 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_24950 4edde8f9af1c1c5048509bbf8e40ac0f 301 Pfam PF00483 Nucleotidyl transferase 13 274 5.4E-29 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4R43_24950 4edde8f9af1c1c5048509bbf8e40ac0f 301 Gene3D G3DSA:3.90.550.10 2 300 1.5E-84 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 Pfam PF00106 short chain dehydrogenase 2 186 2.7E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 Gene3D G3DSA:3.40.50.720 1 219 6.2E-55 T 14-10-2018 A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 SUPERFAMILY SSF51735 2 247 1.2E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 176 2.8E-4 T 14-10-2018 A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 3.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 3.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 3.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13045 4a94bf49603ca03a7c6b32e294cea875 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 3.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_34710 7af08b3c0bf6db3659bfba403d6c4434 713 SUPERFAMILY SSF53067 9 495 9.55E-12 T 14-10-2018 A4R43_34710 7af08b3c0bf6db3659bfba403d6c4434 713 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 9 171 3.3E-25 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 A4R43_34710 7af08b3c0bf6db3659bfba403d6c4434 713 Pfam PF01968 Hydantoinase/oxoprolinase 196 500 8.5E-66 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 A4R43_34710 7af08b3c0bf6db3659bfba403d6c4434 713 Gene3D G3DSA:3.30.420.40 1 125 3.4E-6 T 14-10-2018 A4R43_18020 abcfade9cc7ee8d2994ba1d793232b4e 153 PIRSF PIRSF000239 1 149 1.3E-24 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_18020 abcfade9cc7ee8d2994ba1d793232b4e 153 SUPERFAMILY SSF52833 1 152 7.49E-48 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_18020 abcfade9cc7ee8d2994ba1d793232b4e 153 Gene3D G3DSA:3.40.30.10 1 153 9.3E-54 T 14-10-2018 A4R43_18020 abcfade9cc7ee8d2994ba1d793232b4e 153 Pfam PF00578 AhpC/TSA family 5 130 3.5E-39 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 Hamap MF_00195 GTPase Der [der]. 38 468 35.072 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 SUPERFAMILY SSF52540 173 469 1.24E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14135 b656d3479ee990075f2791994bc18f67 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 214 234 1.2E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 263 278 1.2E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 Gene3D G3DSA:3.40.50.300 211 383 9.3E-43 T 14-10-2018 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 Gene3D G3DSA:3.30.300.20 387 468 1.3E-24 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_14135 b656d3479ee990075f2791994bc18f67 482 SUPERFAMILY SSF52540 40 203 7.42E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14135 b656d3479ee990075f2791994bc18f67 482 Pfam PF01926 50S ribosome-binding GTPase 213 331 1.3E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 Pfam PF01926 50S ribosome-binding GTPase 41 155 2.0E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 Gene3D G3DSA:3.40.50.300 36 198 1.6E-40 T 14-10-2018 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 387 465 1.5E-24 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like A4R43_14135 b656d3479ee990075f2791994bc18f67 482 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 39 465 5.8E-155 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 SMART SM00382 37 175 0.65 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14135 b656d3479ee990075f2791994bc18f67 482 SMART SM00382 210 347 0.22 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14135 b656d3479ee990075f2791994bc18f67 482 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 39 160 7.5E-20 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 212 371 2.9E-21 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4R43_14135 b656d3479ee990075f2791994bc18f67 482 PIRSF PIRSF006485 37 473 2.4E-161 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00385 P450 superfamily signature 246 263 2.6E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00385 P450 superfamily signature 356 367 2.6E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00385 P450 superfamily signature 281 292 2.6E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00385 P450 superfamily signature 347 356 2.6E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 Pfam PF00067 Cytochrome P450 231 376 4.3E-23 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 SUPERFAMILY SSF48264 13 404 4.98E-86 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 205 227 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 137 153 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 326 341 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 356 367 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 298 325 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 281 292 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 91 102 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 347 356 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 PRINTS PR00359 B-class P450 signature 154 169 8.1E-49 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_26400 c6f9427a8c75fd9f9c8f0b780ffd5455 405 Gene3D G3DSA:1.10.630.10 1 405 7.1E-130 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_20570 94b32674722335d6f845d518284a2734 123 Pfam PF03779 SPW repeat 65 109 1.4E-10 T 14-10-2018 IPR005530 SPW repeat A4R43_22695 30cc566e7fcc79c445b4769fa8dc45a5 232 Gene3D G3DSA:1.10.10.10 21 85 8.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22695 30cc566e7fcc79c445b4769fa8dc45a5 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 2.7E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_22695 30cc566e7fcc79c445b4769fa8dc45a5 232 SUPERFAMILY SSF48008 90 225 8.11E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_22695 30cc566e7fcc79c445b4769fa8dc45a5 232 SUPERFAMILY SSF46785 19 88 2.14E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22695 30cc566e7fcc79c445b4769fa8dc45a5 232 SMART SM00345 26 84 2.4E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_22695 30cc566e7fcc79c445b4769fa8dc45a5 232 SMART SM00895 94 217 1.3E-12 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_22695 30cc566e7fcc79c445b4769fa8dc45a5 232 Gene3D G3DSA:1.20.120.530 88 231 1.1E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_22695 30cc566e7fcc79c445b4769fa8dc45a5 232 Pfam PF07729 FCD domain 94 216 3.8E-17 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_16200 1ec9a3a2a99c1b0d504543a61cbd33c0 130 Gene3D G3DSA:3.60.90.10 3 126 5.7E-39 T 14-10-2018 A4R43_16200 1ec9a3a2a99c1b0d504543a61cbd33c0 130 SUPERFAMILY SSF56276 9 119 1.77E-35 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A4R43_16200 1ec9a3a2a99c1b0d504543a61cbd33c0 130 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 6 122 26.121 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A4R43_16200 1ec9a3a2a99c1b0d504543a61cbd33c0 130 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 9 118 3.2E-35 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A4R43_16200 1ec9a3a2a99c1b0d504543a61cbd33c0 130 Pfam PF02675 S-adenosylmethionine decarboxylase 12 118 5.3E-35 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A4R43_18215 036a96fdc438bd2edc9260dddd59b681 127 Pfam PF07883 Cupin domain 31 95 2.2E-8 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_18215 036a96fdc438bd2edc9260dddd59b681 127 Gene3D G3DSA:2.60.120.10 13 124 1.0E-13 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_18215 036a96fdc438bd2edc9260dddd59b681 127 SUPERFAMILY SSF51182 11 108 6.14E-18 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_27540 99d833631cc811afc300ea4040ec7174 124 Gene3D G3DSA:3.40.50.1010 7 100 5.2E-8 T 14-10-2018 A4R43_27540 99d833631cc811afc300ea4040ec7174 124 Pfam PF01936 NYN domain 16 91 4.2E-8 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type A4R43_16130 b968ab8b2ebbcbe8f723811b7d351ff3 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 4.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16130 b968ab8b2ebbcbe8f723811b7d351ff3 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 4.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16130 b968ab8b2ebbcbe8f723811b7d351ff3 202 Gene3D G3DSA:1.10.357.10 9 202 1.5E-68 T 14-10-2018 A4R43_16130 b968ab8b2ebbcbe8f723811b7d351ff3 202 SUPERFAMILY SSF46689 22 86 1.85E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_16130 b968ab8b2ebbcbe8f723811b7d351ff3 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 71 8.2E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06590 db1441c957e769c85a5504ef9282d95e 165 Gene3D G3DSA:3.40.50.300 1 164 1.7E-57 T 14-10-2018 A4R43_06590 db1441c957e769c85a5504ef9282d95e 165 SUPERFAMILY SSF52540 3 158 9.84E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06590 db1441c957e769c85a5504ef9282d95e 165 Pfam PF01202 Shikimate kinase 11 114 4.8E-10 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4R43_06590 db1441c957e769c85a5504ef9282d95e 165 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 4 157 2.0E-52 T 14-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A4R43_15255 613b883dfd7d7c04f2b16d2a2428adf6 159 Pfam PF07883 Cupin domain 50 112 1.3E-18 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_15255 613b883dfd7d7c04f2b16d2a2428adf6 159 Gene3D G3DSA:2.60.120.10 11 153 1.5E-29 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_15255 613b883dfd7d7c04f2b16d2a2428adf6 159 SUPERFAMILY SSF51182 34 139 2.07E-25 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 SUPERFAMILY SSF50494 1 172 4.13E-45 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 Pfam PF13365 Trypsin-like peptidase domain 2 138 3.5E-29 T 14-10-2018 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 SMART SM00228 177 259 9.1E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 SUPERFAMILY SSF50156 135 257 9.99E-20 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 Pfam PF13180 PDZ domain 177 267 1.3E-15 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 Gene3D G3DSA:2.40.10.120 1 170 9.3E-53 T 14-10-2018 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 PRINTS PR00834 HtrA/DegQ protease family signature 31 51 8.7E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 PRINTS PR00834 HtrA/DegQ protease family signature 10 22 8.7E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 PRINTS PR00834 HtrA/DegQ protease family signature 131 148 8.7E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 PRINTS PR00834 HtrA/DegQ protease family signature 217 229 8.7E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 PRINTS PR00834 HtrA/DegQ protease family signature 109 126 8.7E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 PRINTS PR00834 HtrA/DegQ protease family signature 70 94 8.7E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_29465 da8263ef23ae491be4540f1958f8581f 273 Gene3D G3DSA:2.30.42.10 176 272 1.0E-24 T 14-10-2018 A4R43_23080 c17fc88ff9290fc46d356f888397920b 363 SUPERFAMILY SSF52540 3 240 6.04E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23080 c17fc88ff9290fc46d356f888397920b 363 SUPERFAMILY SSF54631 314 356 5.11E-5 T 14-10-2018 A4R43_23080 c17fc88ff9290fc46d356f888397920b 363 Pfam PF00005 ABC transporter 19 164 1.5E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23080 c17fc88ff9290fc46d356f888397920b 363 Gene3D G3DSA:3.40.50.300 1 248 1.7E-75 T 14-10-2018 A4R43_23080 c17fc88ff9290fc46d356f888397920b 363 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_23080 c17fc88ff9290fc46d356f888397920b 363 SMART SM00382 28 214 4.2E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_35795 13b5a2d98e65466d1098f2aa5d88a17c 288 SUPERFAMILY SSF89550 4 275 2.75E-42 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4R43_35795 13b5a2d98e65466d1098f2aa5d88a17c 288 SMART SM00481 6 70 9.2E-14 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A4R43_35795 13b5a2d98e65466d1098f2aa5d88a17c 288 Gene3D G3DSA:3.20.20.140 6 255 1.2E-77 T 14-10-2018 A4R43_35795 13b5a2d98e65466d1098f2aa5d88a17c 288 Pfam PF02811 PHP domain 7 137 6.7E-8 T 14-10-2018 IPR004013 PHP domain GO:0003824 A4R43_35795 13b5a2d98e65466d1098f2aa5d88a17c 288 Gene3D G3DSA:1.10.150.650 102 174 1.2E-77 T 14-10-2018 A4R43_25265 e6ae63c92661aa554840f06fb6ef917b 141 SUPERFAMILY SSF54909 1 116 5.01E-29 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_25265 e6ae63c92661aa554840f06fb6ef917b 141 Pfam PF03795 YCII-related domain 1 112 1.8E-20 T 14-10-2018 IPR005545 YCII-related A4R43_25265 e6ae63c92661aa554840f06fb6ef917b 141 Gene3D G3DSA:3.30.70.1060 1 115 1.8E-33 T 14-10-2018 A4R43_09830 1d464fc1f3bd0a22dee0f1e23dcd8174 320 Pfam PF13280 WYL domain 141 313 1.1E-30 T 14-10-2018 IPR026881 WYL domain A4R43_09830 1d464fc1f3bd0a22dee0f1e23dcd8174 320 SUPERFAMILY SSF46785 5 62 5.77E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09830 1d464fc1f3bd0a22dee0f1e23dcd8174 320 Gene3D G3DSA:1.10.10.10 4 64 4.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09830 1d464fc1f3bd0a22dee0f1e23dcd8174 320 Pfam PF08279 HTH domain 7 61 7.3E-17 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_09830 1d464fc1f3bd0a22dee0f1e23dcd8174 320 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_09830 1d464fc1f3bd0a22dee0f1e23dcd8174 320 PIRSF PIRSF016838 2 320 2.7E-25 T 14-10-2018 IPR028349 Protein PafC A4R43_19180 fadc62f43e5e921493c302b1e4f9d833 449 Gene3D G3DSA:3.30.590.10 117 448 4.5E-100 T 14-10-2018 A4R43_19180 fadc62f43e5e921493c302b1e4f9d833 449 SMART SM01230 114 367 2.4E-103 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_19180 fadc62f43e5e921493c302b1e4f9d833 449 SUPERFAMILY SSF55931 115 447 1.47E-101 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_19180 fadc62f43e5e921493c302b1e4f9d833 449 SUPERFAMILY SSF54368 3 110 1.06E-17 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_19180 fadc62f43e5e921493c302b1e4f9d833 449 Pfam PF00120 Glutamine synthetase, catalytic domain 115 442 1.9E-103 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_19180 fadc62f43e5e921493c302b1e4f9d833 449 Gene3D G3DSA:3.10.20.70 2 113 1.7E-6 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22775 22ad3c9dbdbfc934244cf60e9706bc53 326 SUPERFAMILY SSF51735 103 282 4.32E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22775 22ad3c9dbdbfc934244cf60e9706bc53 326 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_22775 22ad3c9dbdbfc934244cf60e9706bc53 326 SUPERFAMILY SSF52283 35 125 5.74E-10 T 14-10-2018 A4R43_22775 22ad3c9dbdbfc934244cf60e9706bc53 326 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 314 7.3E-6 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_22775 22ad3c9dbdbfc934244cf60e9706bc53 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 283 9.5E-48 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_22775 22ad3c9dbdbfc934244cf60e9706bc53 326 Gene3D G3DSA:3.40.50.720 26 320 1.1E-90 T 14-10-2018 A4R43_22775 22ad3c9dbdbfc934244cf60e9706bc53 326 Gene3D G3DSA:3.40.50.720 101 290 1.1E-90 T 14-10-2018 A4R43_33900 acc2a22a691aebc48e2ee2c3ec7bcdee 187 Pfam PF00673 ribosomal L5P family C-terminus 91 184 3.0E-38 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33900 acc2a22a691aebc48e2ee2c3ec7bcdee 187 Pfam PF00281 Ribosomal protein L5 31 87 8.7E-26 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33900 acc2a22a691aebc48e2ee2c3ec7bcdee 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 42.641 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33900 acc2a22a691aebc48e2ee2c3ec7bcdee 187 Gene3D G3DSA:3.30.1440.10 6 186 1.7E-76 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33900 acc2a22a691aebc48e2ee2c3ec7bcdee 187 PIRSF PIRSF002161 5 187 5.4E-61 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33900 acc2a22a691aebc48e2ee2c3ec7bcdee 187 SUPERFAMILY SSF55282 10 185 4.47E-72 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_20465 fb1c6f37f586fd483b58056bad644caf 465 SUPERFAMILY SSF55486 50 204 8.73E-7 T 14-10-2018 A4R43_20465 fb1c6f37f586fd483b58056bad644caf 465 Pfam PF04228 Putative neutral zinc metallopeptidase 63 255 6.3E-6 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative A4R43_22370 c5b91120ee7fea918a03692ff2d489cc 178 SUPERFAMILY SSF81573 74 132 1.03E-9 T 14-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A4R43_22370 c5b91120ee7fea918a03692ff2d489cc 178 Hamap MF_01398 ATP synthase subunit b [atpF]. 7 149 13.657 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4R43_22370 c5b91120ee7fea918a03692ff2d489cc 178 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 22 168 1.2E-27 T 14-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 A4R43_22370 c5b91120ee7fea918a03692ff2d489cc 178 Pfam PF00430 ATP synthase B/B' CF(0) 18 147 8.9E-29 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 SMART SM00388 230 302 4.5E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 1.5E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 1.5E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 1.5E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 1.5E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 SUPERFAMILY SSF47384 213 301 4.12E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 450 3.0E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 Gene3D G3DSA:3.30.565.10 305 452 2.0E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 SMART SM00304 177 229 4.5E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 SUPERFAMILY SSF55874 292 450 2.1E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 Pfam PF00672 HAMP domain 179 223 2.0E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 SMART SM00387 342 453 3.2E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 SUPERFAMILY SSF158472 180 226 2.09E-6 T 14-10-2018 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 301 8.3E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_25050 f19b1715f4a4814ae6e1c9490a7b55a6 454 Gene3D G3DSA:1.10.287.130 181 303 4.8E-27 T 14-10-2018 A4R43_07150 6854bf713b7e16718e0023b30584b2b2 315 Gene3D G3DSA:3.40.190.10 96 294 1.2E-22 T 14-10-2018 A4R43_07150 6854bf713b7e16718e0023b30584b2b2 315 Gene3D G3DSA:1.10.10.10 3 87 9.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07150 6854bf713b7e16718e0023b30584b2b2 315 Gene3D G3DSA:3.40.190.10 166 270 1.2E-22 T 14-10-2018 A4R43_07150 6854bf713b7e16718e0023b30584b2b2 315 Pfam PF03466 LysR substrate binding domain 90 293 1.2E-27 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_07150 6854bf713b7e16718e0023b30584b2b2 315 SUPERFAMILY SSF53850 91 298 1.05E-25 T 14-10-2018 A4R43_07150 6854bf713b7e16718e0023b30584b2b2 315 SUPERFAMILY SSF46785 5 86 1.02E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07150 6854bf713b7e16718e0023b30584b2b2 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.5E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_39935 2917ec48aaf9466ff46d086228589fd7 334 SUPERFAMILY SSF51556 5 331 1.48E-79 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_39935 2917ec48aaf9466ff46d086228589fd7 334 Pfam PF04909 Amidohydrolase 6 330 5.9E-56 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_39935 2917ec48aaf9466ff46d086228589fd7 334 Gene3D G3DSA:3.20.20.140 5 333 2.0E-90 T 14-10-2018 A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 SMART SM01002 149 297 1.5E-85 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 Gene3D G3DSA:3.40.50.720 3 353 5.1E-138 T 14-10-2018 A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 SMART SM01003 4 137 1.6E-74 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 137 1.2E-45 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 PIRSF PIRSF000183 1 370 2.2E-165 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 368 3.6E-171 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 Gene3D G3DSA:3.40.50.720 130 305 5.1E-138 T 14-10-2018 A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.1E-82 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 SUPERFAMILY SSF52283 2 359 3.57E-64 T 14-10-2018 A4R43_22985 1638860fc9c3fea42d2ee3241ca6b7fb 370 SUPERFAMILY SSF51735 137 303 1.4E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 273 0.0019 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 532 564 0.0066 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 SUPERFAMILY SSF52540 12 261 1.0E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 Gene3D G3DSA:3.40.50.300 306 578 7.7E-88 T 14-10-2018 A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 Gene3D G3DSA:3.40.50.300 10 305 3.8E-84 T 14-10-2018 A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 Pfam PF00005 ABC transporter 33 189 3.0E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 Pfam PF00005 ABC transporter 330 481 9.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 SMART SM00382 41 239 5.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 SMART SM00382 338 530 1.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_23330 42496667f77ba211ac46e41ccb7a6cb7 581 SUPERFAMILY SSF52540 308 552 1.36E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 Pfam PF07690 Major Facilitator Superfamily 26 421 1.5E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 SUPERFAMILY SSF103473 15 468 5.49E-60 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 370 390 3.4E-11 T 14-10-2018 A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 3.4E-11 T 14-10-2018 A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 135 3.4E-11 T 14-10-2018 A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 3.4E-11 T 14-10-2018 A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 Gene3D G3DSA:1.20.1250.20 273 473 5.0E-17 T 14-10-2018 A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 427 5.5E-85 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4R43_09800 b30ea81ad8ddedfb98b32284addec0f7 482 Gene3D G3DSA:1.20.1720.10 21 235 1.0E-42 T 14-10-2018 A4R43_06745 08726d24a8d0f9a8d743c9317bf1534f 97 SMART SM00886 2 95 1.2E-17 T 14-10-2018 IPR013097 Stress responsive alpha-beta barrel A4R43_06745 08726d24a8d0f9a8d743c9317bf1534f 97 SUPERFAMILY SSF54909 1 95 1.41E-22 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_06745 08726d24a8d0f9a8d743c9317bf1534f 97 Pfam PF07876 Stress responsive A/B Barrel Domain 2 94 7.7E-21 T 14-10-2018 IPR013097 Stress responsive alpha-beta barrel A4R43_06745 08726d24a8d0f9a8d743c9317bf1534f 97 Gene3D G3DSA:3.30.70.100 1 97 2.3E-30 T 14-10-2018 A4R43_18275 2dd97dc697cd0a1b17cc45d45a941dbd 279 Pfam PF13460 NAD(P)H-binding 6 179 6.8E-25 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_18275 2dd97dc697cd0a1b17cc45d45a941dbd 279 Gene3D G3DSA:3.40.50.720 2 279 4.4E-65 T 14-10-2018 A4R43_18275 2dd97dc697cd0a1b17cc45d45a941dbd 279 SUPERFAMILY SSF51735 2 275 1.01E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_34855 4ba9cee519c7bebc56fe5838c2e0aec1 206 Pfam PF08044 Domain of unknown function (DUF1707) 1 53 8.3E-23 T 14-10-2018 IPR012551 Protein of unknown function DUF1707 A4R43_16350 7c5f1f8576ff9f679c2b73e5d89a0a7d 380 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 13 294 2.7E-69 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_16350 7c5f1f8576ff9f679c2b73e5d89a0a7d 380 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 380 103.263 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_16350 7c5f1f8576ff9f679c2b73e5d89a0a7d 380 SUPERFAMILY SSF55931 3 373 3.34E-114 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_16350 7c5f1f8576ff9f679c2b73e5d89a0a7d 380 Gene3D G3DSA:3.30.590.20 2 375 1.1E-110 T 14-10-2018 A4R43_16350 7c5f1f8576ff9f679c2b73e5d89a0a7d 380 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 12 300 6.9E-104 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 3.7E-54 T 14-10-2018 A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 9.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 9.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 Gene3D G3DSA:3.40.50.720 1 252 4.4E-72 T 14-10-2018 A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.4E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.4E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.4E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.4E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.4E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 SUPERFAMILY SSF51735 5 252 4.39E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38250 20e620480c7f7769d9e2de3fdf5465f8 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_08490 017a4bff368bce76aa4506864e779805 204 Gene3D G3DSA:1.10.357.10 1 200 1.2E-38 T 14-10-2018 A4R43_08490 017a4bff368bce76aa4506864e779805 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08490 017a4bff368bce76aa4506864e779805 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08490 017a4bff368bce76aa4506864e779805 204 SUPERFAMILY SSF46689 4 77 4.24E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_08490 017a4bff368bce76aa4506864e779805 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_08490 017a4bff368bce76aa4506864e779805 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 4.1E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25340 c9b480625d2c9c8ed4ace587559a52a2 335 SUPERFAMILY SSF55347 127 299 5.07E-30 T 14-10-2018 A4R43_25340 c9b480625d2c9c8ed4ace587559a52a2 335 Gene3D G3DSA:3.40.50.720 2 123 4.8E-39 T 14-10-2018 A4R43_25340 c9b480625d2c9c8ed4ace587559a52a2 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 9.4E-25 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_25340 c9b480625d2c9c8ed4ace587559a52a2 335 Gene3D G3DSA:3.30.360.10 124 335 1.0E-42 T 14-10-2018 A4R43_25340 c9b480625d2c9c8ed4ace587559a52a2 335 SUPERFAMILY SSF51735 3 154 2.15E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_10830 eed0ce836c8a6d234c3259df00eb1f77 275 Gene3D G3DSA:3.10.330.20 2 68 1.7E-24 T 14-10-2018 A4R43_10830 eed0ce836c8a6d234c3259df00eb1f77 275 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 235 2.0E-21 T 14-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A4R43_10830 eed0ce836c8a6d234c3259df00eb1f77 275 PIRSF PIRSF017269 3 268 8.8E-84 T 14-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A4R43_10830 eed0ce836c8a6d234c3259df00eb1f77 275 Gene3D G3DSA:3.40.50.150 70 263 3.9E-61 T 14-10-2018 A4R43_10830 eed0ce836c8a6d234c3259df00eb1f77 275 SUPERFAMILY SSF53335 7 258 4.47E-73 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_10830 eed0ce836c8a6d234c3259df00eb1f77 275 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 6 55 1.7E-28 T 14-10-2018 A4R43_19295 151050e97389d2c5f10d682df73b3c39 368 Pfam PF05762 VWA domain containing CoxE-like protein 147 354 1.1E-56 T 14-10-2018 IPR008912 Uncharacterised protein family CoxE-like A4R43_19295 151050e97389d2c5f10d682df73b3c39 368 PIRSF PIRSF010256 6 365 1.5E-92 T 14-10-2018 IPR011195 Uncharacterised conserved protein UCP010256 A4R43_19295 151050e97389d2c5f10d682df73b3c39 368 Gene3D G3DSA:3.40.50.410 187 320 2.0E-7 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_19295 151050e97389d2c5f10d682df73b3c39 368 SUPERFAMILY SSF53300 189 315 1.46E-14 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_10835 0a2549e1422f20cc5eca77f1b3f65de8 363 PIRSF PIRSF006404 1 363 1.3E-67 T 14-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS A4R43_10835 0a2549e1422f20cc5eca77f1b3f65de8 363 Pfam PF13398 Peptidase M50B-like 56 146 2.3E-5 T 14-10-2018 A4R43_10835 0a2549e1422f20cc5eca77f1b3f65de8 363 SUPERFAMILY SSF54631 248 359 7.68E-6 T 14-10-2018 A4R43_04895 7e2d4e3a7a501e54c775abd0127eb312 478 PIRSF PIRSF006060 1 454 3.6E-37 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_04895 7e2d4e3a7a501e54c775abd0127eb312 478 Gene3D G3DSA:1.20.1740.10 3 453 4.3E-27 T 14-10-2018 A4R43_04895 7e2d4e3a7a501e54c775abd0127eb312 478 Pfam PF13520 Amino acid permease 3 411 1.2E-23 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_12115 3ec35907f673e68d8b1cb2c65fd475f2 142 Gene3D G3DSA:2.30.110.10 27 61 9.5E-7 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_12115 3ec35907f673e68d8b1cb2c65fd475f2 142 Gene3D G3DSA:2.30.110.10 62 140 3.9E-5 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_12115 3ec35907f673e68d8b1cb2c65fd475f2 142 SUPERFAMILY SSF50475 31 131 7.86E-7 T 14-10-2018 A4R43_33935 88713bc55d8815686facbc626b3b780a 148 Gene3D G3DSA:3.100.10.10 68 147 6.8E-22 T 14-10-2018 A4R43_33935 88713bc55d8815686facbc626b3b780a 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 142 - T 14-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33935 88713bc55d8815686facbc626b3b780a 148 SUPERFAMILY SSF52080 9 147 4.45E-38 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A4R43_33935 88713bc55d8815686facbc626b3b780a 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 4.6E-31 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P A4R43_33935 88713bc55d8815686facbc626b3b780a 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 6 148 19.23 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A4R43_33935 88713bc55d8815686facbc626b3b780a 148 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 145 1.7E-42 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_32870 0d6f439f074fcba5689e22d98b67057f 493 SUPERFAMILY SSF56801 3 493 5.1E-132 T 14-10-2018 A4R43_32870 0d6f439f074fcba5689e22d98b67057f 493 ProSitePatterns PS00455 Putative AMP-binding domain signature. 141 152 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_32870 0d6f439f074fcba5689e22d98b67057f 493 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 486 1.7E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_32870 0d6f439f074fcba5689e22d98b67057f 493 Pfam PF00501 AMP-binding enzyme 4 402 6.6E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_32870 0d6f439f074fcba5689e22d98b67057f 493 Gene3D G3DSA:3.30.300.310 398 493 1.7E-28 T 14-10-2018 A4R43_32870 0d6f439f074fcba5689e22d98b67057f 493 Gene3D G3DSA:3.40.50.12780 1 395 3.0E-101 T 14-10-2018 A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 Hamap MF_01987 Ribokinase [rbsK]. 2 287 25.587 T 14-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 Gene3D G3DSA:3.40.1190.20 1 288 8.8E-88 T 14-10-2018 IPR029056 Ribokinase-like A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 SUPERFAMILY SSF53613 1 283 4.37E-71 T 14-10-2018 IPR029056 Ribokinase-like A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 Pfam PF00294 pfkB family carbohydrate kinase 2 280 8.0E-61 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 PRINTS PR00990 Ribokinase signature 170 185 1.1E-30 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 PRINTS PR00990 Ribokinase signature 33 52 1.1E-30 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 PRINTS PR00990 Ribokinase signature 202 213 1.1E-30 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 PRINTS PR00990 Ribokinase signature 6 27 1.1E-30 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_07050 b9813533e2ad6abc4102467846a9ec85 292 PRINTS PR00990 Ribokinase signature 105 118 1.1E-30 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_18520 2b2a9ce05ea69f9ff47ec855d6537a19 272 Pfam PF13649 Methyltransferase domain 92 174 4.5E-6 T 14-10-2018 A4R43_18520 2b2a9ce05ea69f9ff47ec855d6537a19 272 SUPERFAMILY SSF53335 13 245 3.31E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_18520 2b2a9ce05ea69f9ff47ec855d6537a19 272 Gene3D G3DSA:3.40.50.150 10 272 1.5E-63 T 14-10-2018 A4R43_18520 2b2a9ce05ea69f9ff47ec855d6537a19 272 PIRSF PIRSF018249 1 272 9.8E-81 T 14-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 A4R43_02625 bb5e2e1e8bcad5bccffd62e5879f4938 155 Pfam PF07681 DoxX 19 104 2.1E-17 T 14-10-2018 IPR032808 DoxX family A4R43_40165 baf3a0f68654c61dfccda59440e95acf 362 SUPERFAMILY SSF51679 1 333 1.96E-72 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_40165 baf3a0f68654c61dfccda59440e95acf 362 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 356 2.6E-212 T 14-10-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative A4R43_40165 baf3a0f68654c61dfccda59440e95acf 362 Gene3D G3DSA:3.20.20.30 1 344 4.1E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_40165 baf3a0f68654c61dfccda59440e95acf 362 Pfam PF00296 Luciferase-like monooxygenase 1 297 1.3E-57 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_14460 f5975707217955efcc418fd1958eea75 223 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_14460 f5975707217955efcc418fd1958eea75 223 Gene3D G3DSA:3.40.50.2300 1 134 1.7E-30 T 14-10-2018 A4R43_14460 f5975707217955efcc418fd1958eea75 223 PIRSF PIRSF006171 1 223 5.4E-73 T 14-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 A4R43_14460 f5975707217955efcc418fd1958eea75 223 SMART SM00448 2 115 1.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_14460 f5975707217955efcc418fd1958eea75 223 Gene3D G3DSA:1.10.10.10 157 214 2.5E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14460 f5975707217955efcc418fd1958eea75 223 SUPERFAMILY SSF52172 2 162 3.56E-33 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_03655 665518db32d8e17e5d7c2c4b5729be69 355 SUPERFAMILY SSF56266 2 350 1.02E-98 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_03655 665518db32d8e17e5d7c2c4b5729be69 355 Pfam PF03576 Peptidase family S58 19 344 5.3E-108 T 14-10-2018 IPR005321 Peptidase S58, DmpA A4R43_03655 665518db32d8e17e5d7c2c4b5729be69 355 Gene3D G3DSA:3.60.70.12 1 355 3.5E-139 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4R43_22375 842dfba6d9c04b7cd6e3cc5cdbf40b31 83 PRINTS PR00124 ATP synthase C subunit signature 41 56 1.1E-15 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22375 842dfba6d9c04b7cd6e3cc5cdbf40b31 83 PRINTS PR00124 ATP synthase C subunit signature 58 83 1.1E-15 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22375 842dfba6d9c04b7cd6e3cc5cdbf40b31 83 PRINTS PR00124 ATP synthase C subunit signature 20 39 1.1E-15 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22375 842dfba6d9c04b7cd6e3cc5cdbf40b31 83 SUPERFAMILY SSF81333 21 81 1.83E-14 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A4R43_22375 842dfba6d9c04b7cd6e3cc5cdbf40b31 83 Gene3D G3DSA:1.20.20.10 5 83 2.2E-17 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22375 842dfba6d9c04b7cd6e3cc5cdbf40b31 83 Hamap MF_01396 ATP synthase subunit c [atpH]. 18 83 13.348 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4R43_22375 842dfba6d9c04b7cd6e3cc5cdbf40b31 83 Pfam PF00137 ATP synthase subunit C 21 81 3.3E-10 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A4R43_41795 e91c0d642780a485b7237914924496bd 304 Gene3D G3DSA:3.30.2010.10 119 193 3.5E-6 T 14-10-2018 A4R43_41795 e91c0d642780a485b7237914924496bd 304 Pfam PF01435 Peptidase family M48 122 203 3.4E-13 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4R43_23900 bf84d704f925dac10810d8b04b33b0db 406 SUPERFAMILY SSF53955 108 274 6.75E-33 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_23900 bf84d704f925dac10810d8b04b33b0db 406 Pfam PF13406 Transglycosylase SLT domain 191 247 1.9E-7 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 A4R43_23900 bf84d704f925dac10810d8b04b33b0db 406 Gene3D G3DSA:1.10.530.10 118 284 3.9E-9 T 14-10-2018 A4R43_02310 16a76b9f6f0d4e462b204cbcf237f384 251 SUPERFAMILY SSF55729 7 226 7.31E-46 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_02310 16a76b9f6f0d4e462b204cbcf237f384 251 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 68 212 3.7E-38 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 A4R43_02310 16a76b9f6f0d4e462b204cbcf237f384 251 Gene3D G3DSA:3.40.630.70 75 232 7.2E-42 T 14-10-2018 A4R43_32605 a65e204b39ebe3ec96d0ed9352a48951 182 SUPERFAMILY SSF81923 3 69 1.37E-8 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_32605 a65e204b39ebe3ec96d0ed9352a48951 182 SUPERFAMILY SSF81923 78 174 3.01E-12 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_32605 a65e204b39ebe3ec96d0ed9352a48951 182 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 50 3.0E-5 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_32605 a65e204b39ebe3ec96d0ed9352a48951 182 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 132 178 9.1E-11 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_27045 de481759075f43df6c4dc65330c941bf 616 Gene3D G3DSA:3.20.20.300 52 434 6.3E-124 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_27045 de481759075f43df6c4dc65330c941bf 616 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 68 411 2.4E-101 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_27045 de481759075f43df6c4dc65330c941bf 616 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 450 616 4.5E-14 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_27045 de481759075f43df6c4dc65330c941bf 616 Gene3D G3DSA:3.40.50.1700 435 616 2.4E-32 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_27045 de481759075f43df6c4dc65330c941bf 616 SUPERFAMILY SSF52279 451 616 1.01E-19 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_27045 de481759075f43df6c4dc65330c941bf 616 SUPERFAMILY SSF51445 57 441 4.0E-102 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_26130 251f8ca48476726dbd5b57347ace3472 719 Gene3D G3DSA:2.70.98.10 28 289 7.8E-77 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_26130 251f8ca48476726dbd5b57347ace3472 719 SUPERFAMILY SSF74650 30 288 5.81E-66 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A4R43_26130 251f8ca48476726dbd5b57347ace3472 719 Gene3D G3DSA:1.50.10.10 291 718 2.1E-156 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_26130 251f8ca48476726dbd5b57347ace3472 719 Pfam PF00723 Glycosyl hydrolases family 15 298 622 2.8E-20 T 14-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 A4R43_26130 251f8ca48476726dbd5b57347ace3472 719 Pfam PF09137 Glucodextranase, domain N 31 284 3.7E-78 T 14-10-2018 IPR015220 Glucodextranase, N-terminal KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 A4R43_26130 251f8ca48476726dbd5b57347ace3472 719 SUPERFAMILY SSF48208 298 712 1.6E-76 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 216 3.5E-5 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 SUPERFAMILY SSF54534 134 244 6.09E-22 T 14-10-2018 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 418 8.9E-35 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 Hamap MF_00303 Trigger factor [tig]. 1 424 19.553 T 14-10-2018 IPR005215 Trigger factor GO:0015031 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 Gene3D G3DSA:1.10.3120.10 117 422 8.8E-69 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 PIRSF PIRSF003095 1 435 2.4E-119 T 14-10-2018 IPR005215 Trigger factor GO:0015031 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 SUPERFAMILY SSF109998 246 435 3.27E-40 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 SUPERFAMILY SSF102735 1 131 5.23E-36 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 Gene3D G3DSA:3.30.70.1050 1 116 1.5E-32 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 Pfam PF05697 Bacterial trigger factor protein (TF) 2 145 3.0E-41 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 Gene3D G3DSA:3.10.50.40 151 243 8.8E-69 T 14-10-2018 A4R43_39040 5a0a00b731d50c87994f57af4cac0070 469 TIGRFAM TIGR00115 tig: trigger factor 12 417 2.0E-120 T 14-10-2018 IPR005215 Trigger factor GO:0015031 A4R43_32585 c8a9dcf5183227d3cf4a344de656b88b 320 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 303 7.6E-54 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_32585 c8a9dcf5183227d3cf4a344de656b88b 320 Gene3D G3DSA:3.40.50.1100 47 155 5.5E-98 T 14-10-2018 A4R43_32585 c8a9dcf5183227d3cf4a344de656b88b 320 PIRSF PIRSF006278 1 318 5.2E-79 T 14-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase A4R43_32585 c8a9dcf5183227d3cf4a344de656b88b 320 Gene3D G3DSA:3.40.50.1100 14 309 5.5E-98 T 14-10-2018 A4R43_32585 c8a9dcf5183227d3cf4a344de656b88b 320 SUPERFAMILY SSF53686 5 311 3.27E-71 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_24740 f17443fda1e4c2a5f24b90476bfa5977 412 SUPERFAMILY SSF53244 276 406 2.75E-22 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_24740 f17443fda1e4c2a5f24b90476bfa5977 412 Gene3D G3DSA:3.90.190.20 276 409 2.0E-28 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4R43_24740 f17443fda1e4c2a5f24b90476bfa5977 412 TIGRFAM TIGR01499 folC: bifunctional protein FolC 11 404 2.5E-78 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A4R43_24740 f17443fda1e4c2a5f24b90476bfa5977 412 Pfam PF08245 Mur ligase middle domain 30 252 1.8E-9 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4R43_24740 f17443fda1e4c2a5f24b90476bfa5977 412 Pfam PF02875 Mur ligase family, glutamate ligase domain 275 327 4.7E-6 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4R43_24740 f17443fda1e4c2a5f24b90476bfa5977 412 PIRSF PIRSF001563 4 410 1.5E-83 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A4R43_24740 f17443fda1e4c2a5f24b90476bfa5977 412 Gene3D G3DSA:3.40.1190.10 3 272 2.7E-66 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_24740 f17443fda1e4c2a5f24b90476bfa5977 412 SUPERFAMILY SSF53623 11 267 1.21E-59 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4R43_36595 2221f11d16375849b96b25e5cfe2a423 150 SUPERFAMILY SSF48452 9 130 2.51E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_36595 2221f11d16375849b96b25e5cfe2a423 150 Gene3D G3DSA:1.25.40.10 6 138 7.4E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03600 69860f8a5c77567b9749e4c7930924ee 287 Gene3D G3DSA:3.40.50.720 6 268 2.8E-78 T 14-10-2018 A4R43_03600 69860f8a5c77567b9749e4c7930924ee 287 Gene3D G3DSA:3.90.25.10 136 270 2.8E-78 T 14-10-2018 A4R43_03600 69860f8a5c77567b9749e4c7930924ee 287 SUPERFAMILY SSF51735 3 260 6.3E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03600 69860f8a5c77567b9749e4c7930924ee 287 Pfam PF13460 NAD(P)H-binding 9 183 1.4E-22 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 Gene3D G3DSA:2.30.170.50 1 71 2.2E-32 T 14-10-2018 A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 SUPERFAMILY SSF143800 1 66 2.43E-26 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 2.4E-33 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 Pfam PF01197 Ribosomal protein L31 1 66 1.7E-32 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 31.632 T 14-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 PRINTS PR01249 Ribosomal protein L31 signature 32 47 7.3E-22 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 PRINTS PR01249 Ribosomal protein L31 signature 47 65 7.3E-22 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_22430 4273fd0d8270df9eb3ca9da54f277ea5 75 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.3E-22 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_26955 eb04fb6b106066e73cc0d24596c0434f 687 Pfam PF07690 Major Facilitator Superfamily 44 397 4.7E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_26955 eb04fb6b106066e73cc0d24596c0434f 687 SUPERFAMILY SSF103473 29 457 6.8E-32 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_26955 eb04fb6b106066e73cc0d24596c0434f 687 SUPERFAMILY SSF52540 494 663 2.48E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26955 eb04fb6b106066e73cc0d24596c0434f 687 Gene3D G3DSA:3.40.50.300 475 667 4.8E-29 T 14-10-2018 A4R43_26955 eb04fb6b106066e73cc0d24596c0434f 687 Pfam PF02223 Thymidylate kinase 536 658 1.3E-9 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A4R43_26955 eb04fb6b106066e73cc0d24596c0434f 687 Hamap MF_00165 Thymidylate kinase [tmk]. 479 667 14.486 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4R43_26955 eb04fb6b106066e73cc0d24596c0434f 687 Gene3D G3DSA:1.20.1250.20 27 454 9.4E-28 T 14-10-2018 A4R43_39885 d328af1a952211a5a69b0b250cdff91f 258 Gene3D G3DSA:2.60.120.200 30 256 5.3E-80 T 14-10-2018 A4R43_39885 d328af1a952211a5a69b0b250cdff91f 258 SUPERFAMILY SSF49899 34 255 9.5E-59 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_39885 d328af1a952211a5a69b0b250cdff91f 258 Pfam PF08787 Alginate lyase 39 255 1.4E-38 T 14-10-2018 IPR014895 Alginate lyase 2 A4R43_28620 8cdecf9682c3fd124d319c8c9b9c1228 110 SUPERFAMILY SSF52821 4 102 5.89E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_28620 8cdecf9682c3fd124d319c8c9b9c1228 110 SMART SM00450 4 98 6.0E-21 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_28620 8cdecf9682c3fd124d319c8c9b9c1228 110 Gene3D G3DSA:3.40.250.10 5 103 7.1E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily A4R43_28620 8cdecf9682c3fd124d319c8c9b9c1228 110 Pfam PF00581 Rhodanese-like domain 19 94 3.6E-13 T 14-10-2018 IPR001763 Rhodanese-like domain A4R43_26685 fed6b1e64bb37fa48f53443ec0f38394 178 Gene3D G3DSA:1.20.120.450 2 124 9.1E-12 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_26685 fed6b1e64bb37fa48f53443ec0f38394 178 SUPERFAMILY SSF109854 6 127 4.73E-19 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_26685 fed6b1e64bb37fa48f53443ec0f38394 178 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 6 176 2.6E-39 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_26685 fed6b1e64bb37fa48f53443ec0f38394 178 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 6 141 1.1E-22 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_26685 fed6b1e64bb37fa48f53443ec0f38394 178 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 121 6.0E-13 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_19620 00c0c705bd9a07777edfe173c43e0f39 385 SUPERFAMILY SSF53901 6 225 8.37E-49 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_19620 00c0c705bd9a07777edfe173c43e0f39 385 ProSitePatterns PS00737 Thiolases signature 2. 322 338 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A4R43_19620 00c0c705bd9a07777edfe173c43e0f39 385 PIRSF PIRSF000429 1 381 1.5E-66 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_19620 00c0c705bd9a07777edfe173c43e0f39 385 Pfam PF00108 Thiolase, N-terminal domain 2 218 7.9E-22 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_19620 00c0c705bd9a07777edfe173c43e0f39 385 Gene3D G3DSA:3.40.47.10 1 383 1.2E-121 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_19620 00c0c705bd9a07777edfe173c43e0f39 385 SUPERFAMILY SSF53901 248 371 1.97E-31 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_19620 00c0c705bd9a07777edfe173c43e0f39 385 Pfam PF02803 Thiolase, C-terminal domain 259 364 4.2E-10 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_19620 00c0c705bd9a07777edfe173c43e0f39 385 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 69 87 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 A4R43_29195 dc2493240e056f360f103a4cf569f334 257 Pfam PF07070 SpoOM protein 2 215 2.2E-67 T 14-10-2018 IPR009776 Sporulation stage 0, protein M A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 SUPERFAMILY SSF51735 3 245 4.72E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 245 9.0E-53 T 14-10-2018 A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 Gene3D G3DSA:3.40.50.720 2 246 1.8E-74 T 14-10-2018 A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.8E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.8E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.8E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.8E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.8E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31515 744c3d430805707f06c2bb5005fb6b30 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.8E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_04935 e312c192e49065531a565959ef1db2e9 114 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 113 24.939 T 14-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 A4R43_04935 e312c192e49065531a565959ef1db2e9 114 Pfam PF13397 RNA polymerase-binding protein 5 108 2.5E-42 T 14-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 A4R43_04935 e312c192e49065531a565959ef1db2e9 114 ProSitePatterns PS00202 Rubredoxin signature. 51 61 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 A4R43_04935 e312c192e49065531a565959ef1db2e9 114 Gene3D G3DSA:2.20.28.270 2 81 4.4E-14 T 14-10-2018 IPR038638 RbpA superfamily A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 SUPERFAMILY SSF51735 14 259 6.22E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 Gene3D G3DSA:3.40.50.720 14 257 3.4E-74 T 14-10-2018 A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 4.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 4.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 4.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 5.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 5.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 5.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 5.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 5.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 5.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07580 f89cdaa65559482e9e6e98b809af3473 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 255 2.1E-56 T 14-10-2018 A4R43_20770 547e0b684b206fb735e33e87a5d15646 321 Gene3D G3DSA:3.90.180.10 102 304 1.1E-23 T 14-10-2018 A4R43_20770 547e0b684b206fb735e33e87a5d15646 321 SUPERFAMILY SSF51735 119 260 2.2E-19 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_20770 547e0b684b206fb735e33e87a5d15646 321 Gene3D G3DSA:3.90.180.10 2 91 6.8E-8 T 14-10-2018 A4R43_20770 547e0b684b206fb735e33e87a5d15646 321 Gene3D G3DSA:3.40.50.720 124 256 1.1E-23 T 14-10-2018 A4R43_20770 547e0b684b206fb735e33e87a5d15646 321 SUPERFAMILY SSF50129 4 152 7.39E-16 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_24175 8d59d8e4fb8273c8f278d0320c007bc4 228 SUPERFAMILY SSF50800 5 196 1.46E-52 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A4R43_24175 8d59d8e4fb8273c8f278d0320c007bc4 228 Pfam PF03473 MOSC domain 51 154 5.1E-18 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A4R43_24175 8d59d8e4fb8273c8f278d0320c007bc4 228 Gene3D G3DSA:2.40.33.20 2 228 1.5E-60 T 14-10-2018 A4R43_29460 1dddd174571e07ab2cabea0f371366f2 317 Hamap MF_00188 Protease HtpX [htpX]. 8 284 27.65 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A4R43_29460 1dddd174571e07ab2cabea0f371366f2 317 Pfam PF01435 Peptidase family M48 69 284 6.0E-38 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4R43_29460 1dddd174571e07ab2cabea0f371366f2 317 Gene3D G3DSA:3.30.2010.10 61 153 3.7E-28 T 14-10-2018 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 Gene3D G3DSA:3.10.270.10 1 283 2.9E-104 T 14-10-2018 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 PRINTS PR00093 Uricase signature 85 98 7.0E-18 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 PRINTS PR00093 Uricase signature 50 64 7.0E-18 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 PRINTS PR00093 Uricase signature 163 175 7.0E-18 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 PRINTS PR00093 Uricase signature 11 22 7.0E-18 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 PRINTS PR00093 Uricase signature 147 163 7.0E-18 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 TIGRFAM TIGR03383 urate_oxi: urate oxidase 5 280 1.6E-104 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 Pfam PF01014 Uricase 9 132 2.7E-18 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 Pfam PF01014 Uricase 141 275 2.1E-30 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 SUPERFAMILY SSF55620 3 129 4.67E-43 T 14-10-2018 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 177 280 1.0E-30 T 14-10-2018 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 SUPERFAMILY SSF55620 139 282 7.23E-55 T 14-10-2018 A4R43_06035 173d293f1602c2c1026abbb4bd72a983 283 PIRSF PIRSF000241 1 283 1.1E-97 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_08220 4c9fe9c7a8feadb329ef8c14fdabde73 403 Gene3D G3DSA:3.90.1150.10 19 355 1.4E-73 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_08220 4c9fe9c7a8feadb329ef8c14fdabde73 403 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 216 229 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4R43_08220 4c9fe9c7a8feadb329ef8c14fdabde73 403 Pfam PF00155 Aminotransferase class I and II 47 353 6.0E-40 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_08220 4c9fe9c7a8feadb329ef8c14fdabde73 403 SUPERFAMILY SSF53383 8 355 2.58E-67 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_08220 4c9fe9c7a8feadb329ef8c14fdabde73 403 Gene3D G3DSA:3.40.640.10 54 267 1.4E-73 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_19610 676c59d59b3dce98740d39379b377a42 282 Gene3D G3DSA:3.10.129.10 13 148 8.3E-24 T 14-10-2018 A4R43_19610 676c59d59b3dce98740d39379b377a42 282 Pfam PF13452 N-terminal half of MaoC dehydratase 12 130 8.0E-14 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 A4R43_19610 676c59d59b3dce98740d39379b377a42 282 Pfam PF01575 MaoC like domain 161 264 1.2E-25 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_19610 676c59d59b3dce98740d39379b377a42 282 Gene3D G3DSA:3.10.129.10 157 281 4.0E-30 T 14-10-2018 A4R43_19610 676c59d59b3dce98740d39379b377a42 282 SUPERFAMILY SSF54637 167 267 9.72E-25 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_19610 676c59d59b3dce98740d39379b377a42 282 SUPERFAMILY SSF54637 12 141 9.12E-26 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_18605 432b2f2b248eefebd2e0a4a547530729 451 SUPERFAMILY SSF51338 1 70 3.73E-8 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_18605 432b2f2b248eefebd2e0a4a547530729 451 Pfam PF01979 Amidohydrolase family 57 422 7.4E-59 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_18605 432b2f2b248eefebd2e0a4a547530729 451 SUPERFAMILY SSF51556 60 374 2.95E-89 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_18605 432b2f2b248eefebd2e0a4a547530729 451 SUPERFAMILY SSF51338 335 449 1.82E-21 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_18605 432b2f2b248eefebd2e0a4a547530729 451 Gene3D G3DSA:2.30.40.10 13 423 1.9E-117 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_18605 432b2f2b248eefebd2e0a4a547530729 451 Gene3D G3DSA:3.20.20.140 61 374 1.9E-117 T 14-10-2018 A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 Pfam PF13185 GAF domain 35 171 3.8E-15 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 SUPERFAMILY SSF52172 165 237 6.46E-9 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 SUPERFAMILY SSF55781 36 184 3.71E-21 T 14-10-2018 A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 Gene3D G3DSA:1.10.10.10 187 245 2.9E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 Pfam PF03861 ANTAR domain 185 237 3.7E-19 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 SMART SM00065 32 181 1.8E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 Gene3D G3DSA:3.30.450.40 12 186 2.2E-25 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 PIRSF PIRSF036625 5 250 4.0E-51 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4R43_12790 be060a54cbaf2151ddaa673be4a2525d 253 SMART SM01012 183 238 3.1E-21 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_13265 f19cbca839aef35c5fc1da2f1eca16ff 251 Gene3D G3DSA:1.10.10.10 102 183 1.7E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13265 f19cbca839aef35c5fc1da2f1eca16ff 251 Pfam PF04542 Sigma-70 region 2 24 92 8.6E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_13265 f19cbca839aef35c5fc1da2f1eca16ff 251 Gene3D G3DSA:1.10.1740.10 1 101 7.3E-12 T 14-10-2018 A4R43_13265 f19cbca839aef35c5fc1da2f1eca16ff 251 SUPERFAMILY SSF88946 2 96 1.78E-16 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_13265 f19cbca839aef35c5fc1da2f1eca16ff 251 SUPERFAMILY SSF88659 112 177 1.25E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_13265 f19cbca839aef35c5fc1da2f1eca16ff 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 177 1.4E-17 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_39745 415e3ed9460b85962e8ef6ab6cbc8598 129 SUPERFAMILY SSF46785 31 117 4.34E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39745 415e3ed9460b85962e8ef6ab6cbc8598 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.2E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39745 415e3ed9460b85962e8ef6ab6cbc8598 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 2.2E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39745 415e3ed9460b85962e8ef6ab6cbc8598 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 2.2E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39745 415e3ed9460b85962e8ef6ab6cbc8598 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 2.2E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39745 415e3ed9460b85962e8ef6ab6cbc8598 129 Gene3D G3DSA:1.10.10.10 25 129 1.7E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39745 415e3ed9460b85962e8ef6ab6cbc8598 129 Pfam PF01022 Bacterial regulatory protein, arsR family 52 95 2.6E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39745 415e3ed9460b85962e8ef6ab6cbc8598 129 SMART SM00418 44 122 5.5E-27 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_16215 3af5918c7dc893c9727f92df573e61cf 474 Gene3D G3DSA:1.20.1250.20 271 464 7.0E-17 T 14-10-2018 A4R43_16215 3af5918c7dc893c9727f92df573e61cf 474 Pfam PF07690 Major Facilitator Superfamily 22 413 4.4E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_16215 3af5918c7dc893c9727f92df573e61cf 474 SUPERFAMILY SSF103473 10 462 4.97E-59 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_16215 3af5918c7dc893c9727f92df573e61cf 474 Gene3D G3DSA:1.20.1720.10 17 222 8.1E-45 T 14-10-2018 A4R43_07905 b2720e156ece9e82f1e17df004d04216 639 Gene3D G3DSA:3.40.50.11460 527 639 1.6E-14 T 14-10-2018 A4R43_07905 b2720e156ece9e82f1e17df004d04216 639 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 505 3.5E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_07905 b2720e156ece9e82f1e17df004d04216 639 SUPERFAMILY SSF51735 527 638 2.17E-9 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07905 b2720e156ece9e82f1e17df004d04216 639 Gene3D G3DSA:3.40.50.12780 10 414 5.3E-115 T 14-10-2018 A4R43_07905 b2720e156ece9e82f1e17df004d04216 639 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_07905 b2720e156ece9e82f1e17df004d04216 639 Gene3D G3DSA:3.30.300.30 415 516 1.1E-26 T 14-10-2018 A4R43_07905 b2720e156ece9e82f1e17df004d04216 639 SUPERFAMILY SSF56801 8 515 4.32E-149 T 14-10-2018 A4R43_07905 b2720e156ece9e82f1e17df004d04216 639 Pfam PF00501 AMP-binding enzyme 16 421 1.3E-103 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_22580 87492e886599cecfa49cdab9efe4b5f2 388 SUPERFAMILY SSF51658 25 360 1.83E-89 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_22580 87492e886599cecfa49cdab9efe4b5f2 388 Gene3D G3DSA:3.20.20.150 3 380 1.4E-129 T 14-10-2018 A4R43_22580 87492e886599cecfa49cdab9efe4b5f2 388 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 105 327 1.0E-5 T 14-10-2018 A4R43_22580 87492e886599cecfa49cdab9efe4b5f2 388 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 7 378 4.7E-187 T 14-10-2018 IPR013457 Rhamnose isomerase-related A4R43_22580 87492e886599cecfa49cdab9efe4b5f2 388 Pfam PF06134 L-rhamnose isomerase (RhaA) 76 335 1.6E-6 T 14-10-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 A4R43_32365 6815953b01a5c7ec04174c4cce6b4470 209 Pfam PF01553 Acyltransferase 30 147 1.3E-20 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_32365 6815953b01a5c7ec04174c4cce6b4470 209 SMART SM00563 37 149 6.0E-29 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_32365 6815953b01a5c7ec04174c4cce6b4470 209 SUPERFAMILY SSF69593 31 150 2.22E-22 T 14-10-2018 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 Gene3D G3DSA:1.10.630.10 1 391 2.5E-123 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 SUPERFAMILY SSF48264 6 390 1.23E-86 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 336 345 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 334 343 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 313 328 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 129 145 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 285 312 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 343 354 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 79 90 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 268 279 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 146 161 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 PRINTS PR00359 B-class P450 signature 189 211 2.8E-55 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 Pfam PF00067 Cytochrome P450 73 255 2.1E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_28610 4da68f821914d53bd06c3b86a1515192 392 Pfam PF00067 Cytochrome P450 266 358 7.3E-18 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_31315 480378bde93c79e1ebc9ae11361ca4b9 200 SUPERFAMILY SSF48498 89 169 1.61E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_31315 480378bde93c79e1ebc9ae11361ca4b9 200 Gene3D G3DSA:1.10.357.10 62 194 1.9E-15 T 14-10-2018 A4R43_31315 480378bde93c79e1ebc9ae11361ca4b9 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.5E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31315 480378bde93c79e1ebc9ae11361ca4b9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31315 480378bde93c79e1ebc9ae11361ca4b9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31315 480378bde93c79e1ebc9ae11361ca4b9 200 SUPERFAMILY SSF46689 8 91 3.34E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31315 480378bde93c79e1ebc9ae11361ca4b9 200 Gene3D G3DSA:1.10.10.60 2 61 6.8E-19 T 14-10-2018 A4R43_31315 480378bde93c79e1ebc9ae11361ca4b9 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_07415 497159dacf6aa2251c382ea31cfe8fd8 291 SUPERFAMILY SSF161098 56 280 1.07E-49 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_07415 497159dacf6aa2251c382ea31cfe8fd8 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 285 3.4E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_07415 497159dacf6aa2251c382ea31cfe8fd8 291 SUPERFAMILY SSF160964 10 60 5.49E-5 T 14-10-2018 A4R43_07415 497159dacf6aa2251c382ea31cfe8fd8 291 Gene3D G3DSA:1.10.3720.10 52 288 2.2E-57 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_24380 a374247c568414cd25c3b9cf6d8ee8d4 206 SUPERFAMILY SSF46689 7 71 1.28E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_24380 a374247c568414cd25c3b9cf6d8ee8d4 206 Gene3D G3DSA:1.10.357.10 4 194 1.7E-22 T 14-10-2018 A4R43_24380 a374247c568414cd25c3b9cf6d8ee8d4 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 5.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09040 b34e99bb7cd9311ae6cf57f14c5b33f3 279 Pfam PF02673 Bacitracin resistance protein BacA 6 260 4.2E-83 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4R43_09040 b34e99bb7cd9311ae6cf57f14c5b33f3 279 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 265 17.273 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4R43_09040 b34e99bb7cd9311ae6cf57f14c5b33f3 279 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 258 5.3E-78 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4R43_31690 40ce8cf358a4be2ca0fbd8f24bdded86 170 Pfam PF12079 Protein of unknown function (DUF3558) 6 164 4.6E-19 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_21420 3d80234c41b7c29cfbaaedf99bfc050b 362 Gene3D G3DSA:3.40.50.2000 7 344 1.4E-90 T 14-10-2018 A4R43_21420 3d80234c41b7c29cfbaaedf99bfc050b 362 Gene3D G3DSA:3.40.50.2000 161 340 1.4E-90 T 14-10-2018 A4R43_21420 3d80234c41b7c29cfbaaedf99bfc050b 362 SUPERFAMILY SSF53756 5 357 5.39E-90 T 14-10-2018 A4R43_21420 3d80234c41b7c29cfbaaedf99bfc050b 362 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 145 3.7E-32 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_21420 3d80234c41b7c29cfbaaedf99bfc050b 362 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 356 29.955 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_21420 3d80234c41b7c29cfbaaedf99bfc050b 362 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 344 7.7E-35 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 A4R43_06640 868014ab189df3a26be6fed47257375d 284 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 8 92 2.3E-20 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4R43_06640 868014ab189df3a26be6fed47257375d 284 Gene3D G3DSA:3.40.50.10860 8 263 3.4E-76 T 14-10-2018 A4R43_06640 868014ab189df3a26be6fed47257375d 284 SUPERFAMILY SSF53223 3 104 2.59E-25 T 14-10-2018 A4R43_06640 868014ab189df3a26be6fed47257375d 284 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 3 277 27.626 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4R43_06640 868014ab189df3a26be6fed47257375d 284 Gene3D G3DSA:3.40.50.720 103 241 3.4E-76 T 14-10-2018 A4R43_06640 868014ab189df3a26be6fed47257375d 284 SUPERFAMILY SSF51735 105 271 6.62E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04505 a3eb0171640b1b69efd3fc4e6731d88c 688 Pfam PF04185 Phosphoesterase family 43 451 1.4E-96 T 14-10-2018 IPR007312 Phosphoesterase GO:0016788 A4R43_04505 a3eb0171640b1b69efd3fc4e6731d88c 688 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 686 3.7E-202 T 14-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 A4R43_04505 a3eb0171640b1b69efd3fc4e6731d88c 688 Gene3D G3DSA:3.40.720.10 38 205 1.7E-23 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A4R43_04505 a3eb0171640b1b69efd3fc4e6731d88c 688 Gene3D G3DSA:3.40.720.10 326 492 1.5E-47 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A4R43_04505 a3eb0171640b1b69efd3fc4e6731d88c 688 Pfam PF05506 Domain of unknown function (DUF756) 614 677 3.8E-8 T 14-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 A4R43_04505 a3eb0171640b1b69efd3fc4e6731d88c 688 Pfam PF05506 Domain of unknown function (DUF756) 515 597 1.4E-9 T 14-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 A4R43_33010 d5651b4e3136a0493683c3a2d98c63ba 357 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 32 317 2.6E-51 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_33010 d5651b4e3136a0493683c3a2d98c63ba 357 Gene3D G3DSA:3.40.50.1100 52 158 6.7E-67 T 14-10-2018 A4R43_33010 d5651b4e3136a0493683c3a2d98c63ba 357 SUPERFAMILY SSF53686 25 337 4.32E-71 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_33010 d5651b4e3136a0493683c3a2d98c63ba 357 Gene3D G3DSA:3.40.50.1100 36 324 6.7E-67 T 14-10-2018 A4R43_02550 16edcaad7a4554ff009c877e7c566341 1137 SUPERFAMILY SSF52518 435 608 7.66E-13 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_02550 16edcaad7a4554ff009c877e7c566341 1137 Gene3D G3DSA:3.40.920.10 716 918 4.0E-23 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A4R43_02550 16edcaad7a4554ff009c877e7c566341 1137 SUPERFAMILY SSF52518 24 201 2.06E-10 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_02550 16edcaad7a4554ff009c877e7c566341 1137 Gene3D G3DSA:3.40.50.970 14 223 3.2E-23 T 14-10-2018 A4R43_02550 16edcaad7a4554ff009c877e7c566341 1137 SUPERFAMILY SSF53323 719 915 4.58E-28 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A4R43_02550 16edcaad7a4554ff009c877e7c566341 1137 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 725 910 2.0E-24 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A4R43_02550 16edcaad7a4554ff009c877e7c566341 1137 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 455 543 9.1E-7 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_02550 16edcaad7a4554ff009c877e7c566341 1137 SUPERFAMILY SSF52922 270 394 2.92E-8 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 Pfam PF13180 PDZ domain 177 267 1.4E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 Gene3D G3DSA:2.40.10.120 1 173 1.1E-51 T 14-10-2018 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 SUPERFAMILY SSF50494 2 172 2.5E-44 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 Gene3D G3DSA:2.30.42.10 174 271 1.8E-26 T 14-10-2018 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 Pfam PF13365 Trypsin-like peptidase domain 2 138 6.8E-29 T 14-10-2018 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 SUPERFAMILY SSF50156 161 267 1.84E-22 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 PRINTS PR00834 HtrA/DegQ protease family signature 70 94 4.8E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 PRINTS PR00834 HtrA/DegQ protease family signature 31 51 4.8E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 PRINTS PR00834 HtrA/DegQ protease family signature 10 22 4.8E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 PRINTS PR00834 HtrA/DegQ protease family signature 109 126 4.8E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 PRINTS PR00834 HtrA/DegQ protease family signature 131 148 4.8E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 PRINTS PR00834 HtrA/DegQ protease family signature 217 229 4.8E-38 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_01955 08bbc5cd48f561eb1088df612e2e5e77 271 SMART SM00228 177 259 1.7E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 A4R43_07560 492c5cb350b43f7f86bbe31e19e60261 358 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 281 2.5E-66 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_07560 492c5cb350b43f7f86bbe31e19e60261 358 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 5 278 3.6E-37 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_07560 492c5cb350b43f7f86bbe31e19e60261 358 SUPERFAMILY SSF55931 2 337 2.26E-75 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_07560 492c5cb350b43f7f86bbe31e19e60261 358 Gene3D G3DSA:3.30.590.20 1 343 9.5E-89 T 14-10-2018 A4R43_07560 492c5cb350b43f7f86bbe31e19e60261 358 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 358 61.299 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_18075 96cd020e6013a2e7c1ea60cc51082ccd 327 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 233 324 7.6E-29 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_18075 96cd020e6013a2e7c1ea60cc51082ccd 327 Gene3D G3DSA:3.40.47.10 182 327 1.9E-42 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_18075 96cd020e6013a2e7c1ea60cc51082ccd 327 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 119 195 6.5E-25 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_18075 96cd020e6013a2e7c1ea60cc51082ccd 327 SUPERFAMILY SSF53901 14 324 9.66E-62 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_18075 96cd020e6013a2e7c1ea60cc51082ccd 327 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 16 324 3.9E-99 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_18075 96cd020e6013a2e7c1ea60cc51082ccd 327 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 14 326 57.383 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4R43_18075 96cd020e6013a2e7c1ea60cc51082ccd 327 Gene3D G3DSA:3.40.47.10 5 181 3.1E-63 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_11285 5f6f21a99e41e5200459b993ab079332 280 Gene3D G3DSA:1.10.12.10 222 278 7.2E-19 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_11285 5f6f21a99e41e5200459b993ab079332 280 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 120 140 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_11285 5f6f21a99e41e5200459b993ab079332 280 SUPERFAMILY SSF52096 14 279 3.73E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_11285 5f6f21a99e41e5200459b993ab079332 280 Gene3D G3DSA:3.90.226.10 4 221 1.6E-61 T 14-10-2018 A4R43_11285 5f6f21a99e41e5200459b993ab079332 280 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 279 8.8E-48 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_36810 be919e18637311929a59c65253a26da4 200 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 25 170 6.5E-17 T 14-10-2018 IPR018958 Knr4/Smi1-like domain A4R43_36810 be919e18637311929a59c65253a26da4 200 SMART SM00860 25 177 7.5E-4 T 14-10-2018 IPR018958 Knr4/Smi1-like domain A4R43_36810 be919e18637311929a59c65253a26da4 200 SUPERFAMILY SSF160631 21 171 6.8E-7 T 14-10-2018 A4R43_03545 eec75492346c5f8308304212f3dc24c8 265 Pfam PF01063 Amino-transferase class IV 28 236 2.3E-32 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A4R43_03545 eec75492346c5f8308304212f3dc24c8 265 Gene3D G3DSA:3.20.10.10 118 260 4.5E-18 T 14-10-2018 A4R43_03545 eec75492346c5f8308304212f3dc24c8 265 SUPERFAMILY SSF56752 21 244 2.62E-34 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A4R43_03545 eec75492346c5f8308304212f3dc24c8 265 Gene3D G3DSA:3.30.470.10 8 116 3.3E-6 T 14-10-2018 A4R43_39965 0ed46601a0226df9c724223aa4a0fab2 866 Pfam PF00391 PEP-utilising enzyme, mobile domain 790 860 4.0E-20 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4R43_39965 0ed46601a0226df9c724223aa4a0fab2 866 Gene3D G3DSA:3.50.30.10 763 864 1.7E-29 T 14-10-2018 A4R43_39965 0ed46601a0226df9c724223aa4a0fab2 866 SUPERFAMILY SSF52009 763 863 3.79E-26 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A4R43_39965 0ed46601a0226df9c724223aa4a0fab2 866 Gene3D G3DSA:3.30.470.20 179 311 1.6E-42 T 14-10-2018 A4R43_39965 0ed46601a0226df9c724223aa4a0fab2 866 SUPERFAMILY SSF56059 3 338 7.06E-95 T 14-10-2018 A4R43_39965 0ed46601a0226df9c724223aa4a0fab2 866 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 13 312 1.9E-91 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4R43_39965 0ed46601a0226df9c724223aa4a0fab2 866 Gene3D G3DSA:3.30.1490.20 1 178 1.5E-65 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_32575 774ae97d1099e18ed62246cf031c8d1a 190 Gene3D G3DSA:1.10.357.10 5 189 9.3E-35 T 14-10-2018 A4R43_32575 774ae97d1099e18ed62246cf031c8d1a 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32575 774ae97d1099e18ed62246cf031c8d1a 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32575 774ae97d1099e18ed62246cf031c8d1a 190 SUPERFAMILY SSF46689 10 79 1.45E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_32575 774ae97d1099e18ed62246cf031c8d1a 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 2.1E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32575 774ae97d1099e18ed62246cf031c8d1a 190 SUPERFAMILY SSF48498 111 184 1.42E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_07995 af604ffb5a3b6632535c8ac8727fc6cf 125 SUPERFAMILY SSF46955 1 104 3.59E-29 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_07995 af604ffb5a3b6632535c8ac8727fc6cf 125 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_07995 af604ffb5a3b6632535c8ac8727fc6cf 125 SMART SM00422 1 70 3.6E-33 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_07995 af604ffb5a3b6632535c8ac8727fc6cf 125 Gene3D G3DSA:1.10.1660.10 1 125 3.3E-30 T 14-10-2018 A4R43_07995 af604ffb5a3b6632535c8ac8727fc6cf 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.2E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_07995 af604ffb5a3b6632535c8ac8727fc6cf 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.2E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_07995 af604ffb5a3b6632535c8ac8727fc6cf 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.2E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_07995 af604ffb5a3b6632535c8ac8727fc6cf 125 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.9E-19 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_37270 dde0e50ac75e5c0364b2417aab75e546 138 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 14 137 2.7E-36 T 14-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 A4R43_37270 dde0e50ac75e5c0364b2417aab75e546 138 Pfam PF12680 SnoaL-like domain 23 127 1.2E-9 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_37270 dde0e50ac75e5c0364b2417aab75e546 138 SUPERFAMILY SSF54427 11 137 8.98E-34 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_37270 dde0e50ac75e5c0364b2417aab75e546 138 Gene3D G3DSA:3.10.450.50 1 138 1.9E-38 T 14-10-2018 A4R43_15445 318aa49089f6bcd0e002115247af2548 155 SUPERFAMILY SSF46785 6 65 3.28E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15445 318aa49089f6bcd0e002115247af2548 155 Gene3D G3DSA:3.30.70.920 58 140 6.8E-23 T 14-10-2018 A4R43_15445 318aa49089f6bcd0e002115247af2548 155 SUPERFAMILY SSF54909 68 141 3.0E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_15445 318aa49089f6bcd0e002115247af2548 155 Gene3D G3DSA:1.10.10.10 1 57 3.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15445 318aa49089f6bcd0e002115247af2548 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 7.7E-18 T 14-10-2018 A4R43_15445 318aa49089f6bcd0e002115247af2548 155 SMART SM00344 6 112 6.9E-37 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_15445 318aa49089f6bcd0e002115247af2548 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.9E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_15445 318aa49089f6bcd0e002115247af2548 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.9E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_15445 318aa49089f6bcd0e002115247af2548 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.9E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_15445 318aa49089f6bcd0e002115247af2548 155 Pfam PF01037 Lrp/AsnC ligand binding domain 79 138 5.3E-15 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_15445 318aa49089f6bcd0e002115247af2548 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4R43_13790 dc935918f002af810be40c8bde895701 306 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 26 225 1.4E-27 T 14-10-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain A4R43_39810 4305ec7ea729a70e7221c8ac331613c5 158 SUPERFAMILY SSF46785 19 154 1.91E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39810 4305ec7ea729a70e7221c8ac331613c5 158 Gene3D G3DSA:1.10.10.10 2 156 1.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39810 4305ec7ea729a70e7221c8ac331613c5 158 Pfam PF12802 MarR family 60 106 5.4E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_39810 4305ec7ea729a70e7221c8ac331613c5 158 SMART SM00347 38 142 5.0E-4 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_11335 ffbc1eb8238422ccebc1447146ab2ef1 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.589 T 14-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid A4R43_11335 ffbc1eb8238422ccebc1447146ab2ef1 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 2.0E-25 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_11335 ffbc1eb8238422ccebc1447146ab2ef1 101 SUPERFAMILY SSF57716 2 101 3.14E-35 T 14-10-2018 A4R43_11335 ffbc1eb8238422ccebc1447146ab2ef1 101 Gene3D G3DSA:4.10.830.10 39 101 2.0E-24 T 14-10-2018 A4R43_21810 7b37f7f8c175b7674d5a377d06e8ce40 186 Pfam PF01569 PAP2 superfamily 57 167 2.4E-19 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_21810 7b37f7f8c175b7674d5a377d06e8ce40 186 SUPERFAMILY SSF48317 16 170 9.03E-32 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4R43_21810 7b37f7f8c175b7674d5a377d06e8ce40 186 Gene3D G3DSA:1.20.144.10 86 186 1.4E-19 T 14-10-2018 A4R43_21810 7b37f7f8c175b7674d5a377d06e8ce40 186 SMART SM00014 55 167 1.8E-14 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_21515 a7310273352c980fdc7b8d78d6d0a315 684 SUPERFAMILY SSF53756 98 411 3.14E-36 T 14-10-2018 A4R43_21515 a7310273352c980fdc7b8d78d6d0a315 684 Pfam PF00534 Glycosyl transferases group 1 233 394 2.7E-22 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_21515 a7310273352c980fdc7b8d78d6d0a315 684 Gene3D G3DSA:3.40.50.2000 147 400 3.7E-35 T 14-10-2018 A4R43_21515 a7310273352c980fdc7b8d78d6d0a315 684 Gene3D G3DSA:3.40.50.2000 213 398 3.7E-35 T 14-10-2018 A4R43_34575 49b19cb2e9892201c2a5e8bc71d9a269 172 Gene3D G3DSA:3.40.1280.10 37 171 4.4E-26 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_34575 49b19cb2e9892201c2a5e8bc71d9a269 172 Pfam PF00588 SpoU rRNA Methylase family 38 166 1.3E-19 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4R43_34575 49b19cb2e9892201c2a5e8bc71d9a269 172 SUPERFAMILY SSF75217 35 168 2.16E-24 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 Pfam PF01380 SIS domain 469 598 2.4E-20 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 Pfam PF01380 SIS domain 297 421 8.4E-34 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 SUPERFAMILY SSF56235 2 243 5.32E-65 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 SUPERFAMILY SSF53697 253 620 2.04E-105 T 14-10-2018 A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 Gene3D G3DSA:3.60.20.10 2 247 3.1E-74 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 Gene3D G3DSA:3.40.50.10490 258 619 1.3E-137 T 14-10-2018 A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 620 40.581 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 Pfam PF13522 Glutamine amidotransferase domain 68 201 5.0E-20 T 14-10-2018 A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 620 7.7E-245 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4R43_34155 b1aa3dc11bf416d79462183420e28dcb 620 Gene3D G3DSA:3.40.50.10490 454 605 1.3E-137 T 14-10-2018 A4R43_39155 26552362518bd5082dc89ff3c2b54001 397 SUPERFAMILY SSF53822 95 372 5.05E-45 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_39155 26552362518bd5082dc89ff3c2b54001 397 Gene3D G3DSA:3.40.50.2300 98 359 2.4E-49 T 14-10-2018 A4R43_39155 26552362518bd5082dc89ff3c2b54001 397 Gene3D G3DSA:3.40.50.2300 200 371 2.4E-49 T 14-10-2018 A4R43_39155 26552362518bd5082dc89ff3c2b54001 397 Pfam PF13407 Periplasmic binding protein domain 98 350 1.5E-35 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_04170 18e03f19088153200f495b4bffc32aa3 182 SUPERFAMILY SSF101874 14 179 5.36E-46 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily A4R43_04170 18e03f19088153200f495b4bffc32aa3 182 Pfam PF04264 YceI-like domain 16 178 4.9E-39 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4R43_04170 18e03f19088153200f495b4bffc32aa3 182 SMART SM00867 15 179 8.2E-53 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4R43_04170 18e03f19088153200f495b4bffc32aa3 182 Gene3D G3DSA:2.40.128.110 13 181 2.8E-46 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily A4R43_22320 04d69aa292030e1379d4d2efc937fcfb 138 SUPERFAMILY SSF50475 1 136 2.48E-23 T 14-10-2018 A4R43_22320 04d69aa292030e1379d4d2efc937fcfb 138 Gene3D G3DSA:2.30.110.10 1 135 2.2E-25 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_22320 04d69aa292030e1379d4d2efc937fcfb 138 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 3 100 1.9E-6 T 14-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 Gene3D G3DSA:3.40.30.120 378 472 9.9E-31 T 14-10-2018 A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 Pfam PF01494 FAD binding domain 3 333 4.0E-94 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 SUPERFAMILY SSF51905 3 349 2.18E-68 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 Gene3D G3DSA:3.30.70.2450 171 256 2.1E-123 T 14-10-2018 A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 Gene3D G3DSA:3.50.50.60 3 331 2.1E-123 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 3.0E-47 T 14-10-2018 A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 3.0E-47 T 14-10-2018 A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 298 3.0E-47 T 14-10-2018 A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 318 3.0E-47 T 14-10-2018 A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.0E-47 T 14-10-2018 A4R43_03555 7a8bc2745bdf2416ede8d4fdd5c57a9d 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 3.0E-47 T 14-10-2018 A4R43_28975 c0985e4e7ffdfd3be9e56284b0ee6b06 727 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 38 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_28975 c0985e4e7ffdfd3be9e56284b0ee6b06 727 Gene3D G3DSA:3.30.200.20 8 91 5.1E-16 T 14-10-2018 A4R43_28975 c0985e4e7ffdfd3be9e56284b0ee6b06 727 SUPERFAMILY SSF56112 7 257 1.09E-61 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_28975 c0985e4e7ffdfd3be9e56284b0ee6b06 727 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 128 140 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_28975 c0985e4e7ffdfd3be9e56284b0ee6b06 727 Gene3D G3DSA:1.10.510.10 92 263 9.6E-39 T 14-10-2018 A4R43_28975 c0985e4e7ffdfd3be9e56284b0ee6b06 727 Gene3D G3DSA:3.30.565.40 365 476 4.4E-5 T 14-10-2018 A4R43_28975 c0985e4e7ffdfd3be9e56284b0ee6b06 727 Pfam PF00069 Protein kinase domain 9 249 4.6E-42 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 Gene3D G3DSA:2.60.40.10 639 750 2.4E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 SUPERFAMILY SSF51445 10 398 2.21E-87 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 Pfam PF14310 Fibronectin type III-like domain 668 737 1.6E-15 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 SMART SM01217 668 737 4.1E-24 T 14-10-2018 IPR026891 Fibronectin type III-like domain A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 175 191 2.4E-16 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 129 148 2.4E-16 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 276 294 2.4E-16 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 106 122 2.4E-16 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 206 222 2.4E-16 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 Gene3D G3DSA:3.20.20.300 18 372 4.9E-91 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 399 632 1.6E-49 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 SUPERFAMILY SSF52279 399 632 2.48E-46 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 31 356 2.6E-63 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_06385 25ba3bbd8b87f7d6fcb1acfcd43ee6fa 766 Gene3D G3DSA:3.40.50.1700 385 633 1.7E-65 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A4R43_12015 f4629ea1b69b8fb722c723598e4b4ef6 430 SUPERFAMILY SSF48208 22 425 5.5E-68 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_12015 f4629ea1b69b8fb722c723598e4b4ef6 430 Gene3D G3DSA:1.50.10.10 6 424 2.0E-107 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_02295 ec09d0ab9181e7cb708032a4f62b40fd 362 Pfam PF01063 Amino-transferase class IV 75 317 1.4E-33 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A4R43_02295 ec09d0ab9181e7cb708032a4f62b40fd 362 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 360 5.4E-118 T 14-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A4R43_02295 ec09d0ab9181e7cb708032a4f62b40fd 362 SUPERFAMILY SSF56752 7 358 2.22E-110 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A4R43_02295 ec09d0ab9181e7cb708032a4f62b40fd 362 ProSitePatterns PS00770 Aminotransferases class-IV signature. 238 267 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 A4R43_02295 ec09d0ab9181e7cb708032a4f62b40fd 362 Gene3D G3DSA:3.20.10.10 176 344 5.8E-127 T 14-10-2018 A4R43_02295 ec09d0ab9181e7cb708032a4f62b40fd 362 PIRSF PIRSF006468 5 362 3.5E-122 T 14-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A4R43_02295 ec09d0ab9181e7cb708032a4f62b40fd 362 Gene3D G3DSA:3.30.470.10 30 357 5.8E-127 T 14-10-2018 A4R43_35315 7a26634e365f0b926ec8fd251f0fb5d2 557 Gene3D G3DSA:3.30.300.30 453 554 6.6E-26 T 14-10-2018 A4R43_35315 7a26634e365f0b926ec8fd251f0fb5d2 557 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_35315 7a26634e365f0b926ec8fd251f0fb5d2 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 466 542 9.4E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_35315 7a26634e365f0b926ec8fd251f0fb5d2 557 Gene3D G3DSA:3.40.50.12780 11 452 5.4E-112 T 14-10-2018 A4R43_35315 7a26634e365f0b926ec8fd251f0fb5d2 557 SUPERFAMILY SSF56801 19 552 2.88E-137 T 14-10-2018 A4R43_35315 7a26634e365f0b926ec8fd251f0fb5d2 557 Pfam PF00501 AMP-binding enzyme 27 455 2.0E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00097 Anthranilate synthase component II signature 226 235 4.3E-6 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00097 Anthranilate synthase component II signature 254 265 4.3E-6 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00097 Anthranilate synthase component II signature 345 358 4.3E-6 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 8 371 6.1E-135 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 6 374 45.034 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 SUPERFAMILY SSF52317 155 371 4.13E-50 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 Gene3D G3DSA:3.50.30.20 6 157 3.0E-57 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 SMART SM01097 6 136 1.9E-84 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 223 237 1.1E-32 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 271 288 1.1E-32 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 184 198 1.1E-32 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 296 307 1.1E-32 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 254 270 1.1E-32 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 SUPERFAMILY SSF52021 7 138 1.57E-54 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 Pfam PF00117 Glutamine amidotransferase class-I 188 368 1.8E-38 T 14-10-2018 IPR017926 Glutamine amidotransferase A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00096 Glutamine amidotransferase superfamily signature 345 358 1.7E-11 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00096 Glutamine amidotransferase superfamily signature 226 235 1.7E-11 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 PRINTS PR00096 Glutamine amidotransferase superfamily signature 254 265 1.7E-11 T 14-10-2018 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 8 133 1.7E-51 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04730 fc7ccc9cbb25e17f44d504780f1cb8a0 374 Gene3D G3DSA:3.40.50.880 158 373 9.0E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_10570 b5e3549df103ee5b6536f998c500c5af 114 Gene3D G3DSA:3.10.180.10 8 113 2.6E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_10570 b5e3549df103ee5b6536f998c500c5af 114 SUPERFAMILY SSF54593 4 113 7.38E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_10570 b5e3549df103ee5b6536f998c500c5af 114 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 108 1.9E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_03230 2998cd385cee13978573b2cc29b8d3ea 229 Gene3D G3DSA:3.40.50.150 61 229 7.4E-50 T 14-10-2018 A4R43_03230 2998cd385cee13978573b2cc29b8d3ea 229 SUPERFAMILY SSF53335 5 224 4.32E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_03230 2998cd385cee13978573b2cc29b8d3ea 229 Pfam PF04989 Cephalosporin hydroxylase 51 184 6.7E-18 T 14-10-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 A4R43_35070 d0990a83871c5cf5b2b8d54afe8dad9c 336 Gene3D G3DSA:3.40.50.10470 133 324 1.6E-73 T 14-10-2018 A4R43_35070 d0990a83871c5cf5b2b8d54afe8dad9c 336 SUPERFAMILY SSF100950 8 332 2.09E-78 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_35070 d0990a83871c5cf5b2b8d54afe8dad9c 336 Pfam PF01008 Initiation factor 2 subunit family 60 324 9.1E-48 T 14-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A4R43_35070 d0990a83871c5cf5b2b8d54afe8dad9c 336 Gene3D G3DSA:1.20.120.420 39 132 1.6E-73 T 14-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4R43_03645 6714e29d89b31642cffbaae1907799ef 425 Pfam PF13378 Enolase C-terminal domain-like 175 388 7.1E-50 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_03645 6714e29d89b31642cffbaae1907799ef 425 Gene3D G3DSA:3.20.20.120 138 381 2.9E-187 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_03645 6714e29d89b31642cffbaae1907799ef 425 SUPERFAMILY SSF51604 138 397 2.18E-71 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_03645 6714e29d89b31642cffbaae1907799ef 425 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 36 138 1.0E-4 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_03645 6714e29d89b31642cffbaae1907799ef 425 SUPERFAMILY SSF54826 6 138 3.71E-26 T 14-10-2018 A4R43_03645 6714e29d89b31642cffbaae1907799ef 425 SMART SM00922 172 266 2.5E-22 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_03645 6714e29d89b31642cffbaae1907799ef 425 Gene3D G3DSA:3.30.390.10 8 418 2.9E-187 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_19115 31d907a35c06505a4ef7c2f5e300ed52 269 SMART SM00382 35 224 2.1E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_19115 31d907a35c06505a4ef7c2f5e300ed52 269 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_19115 31d907a35c06505a4ef7c2f5e300ed52 269 Pfam PF00005 ABC transporter 28 174 1.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_19115 31d907a35c06505a4ef7c2f5e300ed52 269 SUPERFAMILY SSF52540 11 237 2.07E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19115 31d907a35c06505a4ef7c2f5e300ed52 269 Gene3D G3DSA:3.40.50.300 11 263 1.2E-66 T 14-10-2018 A4R43_35120 6c4c27ff1045b31107f968fd48f76351 206 Gene3D G3DSA:3.90.950.10 1 201 4.0E-53 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4R43_35120 6c4c27ff1045b31107f968fd48f76351 206 Pfam PF02545 Maf-like protein 2 195 8.1E-41 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 A4R43_35120 6c4c27ff1045b31107f968fd48f76351 206 PIRSF PIRSF006305 1 202 6.1E-38 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 A4R43_35120 6c4c27ff1045b31107f968fd48f76351 206 Hamap MF_00528 Septum formation protein Maf [maf]. 2 200 27.276 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 A4R43_35120 6c4c27ff1045b31107f968fd48f76351 206 SUPERFAMILY SSF52972 2 195 9.16E-45 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4R43_35120 6c4c27ff1045b31107f968fd48f76351 206 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 193 4.5E-46 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 A4R43_38800 797f5bf1ce314c648ebddc5ff940b369 144 Gene3D G3DSA:2.40.50.140 1 112 6.6E-31 T 14-10-2018 A4R43_38800 797f5bf1ce314c648ebddc5ff940b369 144 SUPERFAMILY SSF50249 1 118 2.94E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_38800 797f5bf1ce314c648ebddc5ff940b369 144 Pfam PF00436 Single-strand binding protein family 1 97 1.2E-16 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A4R43_38800 797f5bf1ce314c648ebddc5ff940b369 144 PIRSF PIRSF002070 1 134 4.5E-21 T 14-10-2018 A4R43_41255 5123d8f04c3b85e1a66c12b47d919d89 197 Pfam PF03713 Domain of unknown function (DUF305) 55 196 1.8E-42 T 14-10-2018 IPR005183 Domain of unknown function DUF305 A4R43_41255 5123d8f04c3b85e1a66c12b47d919d89 197 Gene3D G3DSA:1.20.1260.10 45 197 2.2E-49 T 14-10-2018 IPR012347 Ferritin-like A4R43_36030 734946b5ec5e3b178aa98dd1ba2a0c08 458 SUPERFAMILY SSF63411 257 452 2.83E-31 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4R43_36030 734946b5ec5e3b178aa98dd1ba2a0c08 458 Gene3D G3DSA:3.30.830.10 250 443 1.6E-37 T 14-10-2018 A4R43_36030 734946b5ec5e3b178aa98dd1ba2a0c08 458 Gene3D G3DSA:3.30.830.10 39 243 1.1E-30 T 14-10-2018 A4R43_36030 734946b5ec5e3b178aa98dd1ba2a0c08 458 Pfam PF00675 Insulinase (Peptidase family M16) 84 187 1.4E-6 T 14-10-2018 IPR011765 Peptidase M16, N-terminal A4R43_36030 734946b5ec5e3b178aa98dd1ba2a0c08 458 Pfam PF05193 Peptidase M16 inactive domain 199 370 6.0E-16 T 14-10-2018 IPR007863 Peptidase M16, C-terminal A4R43_36030 734946b5ec5e3b178aa98dd1ba2a0c08 458 SUPERFAMILY SSF63411 39 241 1.1E-30 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4R43_28645 a955d101605be81edf04b9279e988a12 276 SMART SM00448 14 138 2.0E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_28645 a955d101605be81edf04b9279e988a12 276 Pfam PF04397 LytTr DNA-binding domain 175 269 3.4E-23 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A4R43_28645 a955d101605be81edf04b9279e988a12 276 SMART SM00850 173 270 2.0E-32 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A4R43_28645 a955d101605be81edf04b9279e988a12 276 Gene3D G3DSA:2.40.50.40 163 232 1.7E-8 T 14-10-2018 A4R43_28645 a955d101605be81edf04b9279e988a12 276 Gene3D G3DSA:3.40.50.2300 8 150 9.4E-26 T 14-10-2018 A4R43_28645 a955d101605be81edf04b9279e988a12 276 SUPERFAMILY SSF52172 13 149 3.98E-25 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_28645 a955d101605be81edf04b9279e988a12 276 Pfam PF00072 Response regulator receiver domain 16 139 3.5E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_13465 c9572e0001e642b801e51ee6f25ab224 526 Gene3D G3DSA:3.10.105.10 297 498 1.6E-32 T 14-10-2018 A4R43_13465 c9572e0001e642b801e51ee6f25ab224 526 Gene3D G3DSA:3.40.190.10 27 286 4.8E-61 T 14-10-2018 A4R43_13465 c9572e0001e642b801e51ee6f25ab224 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 432 1.1E-69 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_13465 c9572e0001e642b801e51ee6f25ab224 526 PIRSF PIRSF002741 1 521 1.0E-70 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_13465 c9572e0001e642b801e51ee6f25ab224 526 SUPERFAMILY SSF53850 35 519 8.32E-101 T 14-10-2018 A4R43_29010 869a2409ccafbb1b0d13c9722bb8faca 460 Gene3D G3DSA:3.90.1300.10 2 459 3.2E-124 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_29010 869a2409ccafbb1b0d13c9722bb8faca 460 Pfam PF01425 Amidase 360 442 6.0E-15 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_29010 869a2409ccafbb1b0d13c9722bb8faca 460 Pfam PF01425 Amidase 25 302 1.5E-71 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_29010 869a2409ccafbb1b0d13c9722bb8faca 460 SUPERFAMILY SSF75304 1 459 7.19E-120 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 SUPERFAMILY SSF51905 5 358 2.5E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 Gene3D G3DSA:3.50.50.60 7 336 5.9E-78 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 Pfam PF01494 FAD binding domain 4 335 1.7E-49 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 Gene3D G3DSA:3.30.70.2450 182 263 5.9E-78 T 14-10-2018 A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 5.2E-31 T 14-10-2018 A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 5.2E-31 T 14-10-2018 A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 5.2E-31 T 14-10-2018 A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.2E-31 T 14-10-2018 A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 325 5.2E-31 T 14-10-2018 A4R43_40865 83ad9b39666438f0b4cbeb8bf10d2a16 495 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 341 5.2E-31 T 14-10-2018 A4R43_10100 f9461abace45724815f3e6a99bf03aac 337 PIRSF PIRSF017082 7 332 7.8E-64 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_10100 f9461abace45724815f3e6a99bf03aac 337 Gene3D G3DSA:3.40.190.10 141 259 4.8E-69 T 14-10-2018 A4R43_10100 f9461abace45724815f3e6a99bf03aac 337 Gene3D G3DSA:3.40.190.150 46 324 4.8E-69 T 14-10-2018 A4R43_10100 f9461abace45724815f3e6a99bf03aac 337 SUPERFAMILY SSF53850 133 300 2.52E-12 T 14-10-2018 A4R43_10100 f9461abace45724815f3e6a99bf03aac 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 328 3.1E-42 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_11140 3fad2525c6bc743b625f30fe47f45eae 247 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 245 38.879 T 14-10-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 A4R43_11140 3fad2525c6bc743b625f30fe47f45eae 247 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 245 4.3E-81 T 14-10-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 A4R43_11140 3fad2525c6bc743b625f30fe47f45eae 247 SUPERFAMILY SSF56235 2 244 1.25E-18 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_11140 3fad2525c6bc743b625f30fe47f45eae 247 Gene3D G3DSA:3.60.20.10 2 247 2.4E-81 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_11140 3fad2525c6bc743b625f30fe47f45eae 247 Pfam PF13522 Glutamine amidotransferase domain 75 216 1.3E-14 T 14-10-2018 A4R43_17370 84865981c071c7cf81ae316744fbba36 307 Gene3D G3DSA:1.10.620.20 2 270 2.8E-110 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4R43_17370 84865981c071c7cf81ae316744fbba36 307 SUPERFAMILY SSF47240 6 299 4.06E-83 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_17370 84865981c071c7cf81ae316744fbba36 307 PIRSF PIRSF000346 1 306 5.5E-99 T 14-10-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 A4R43_17370 84865981c071c7cf81ae316744fbba36 307 Pfam PF03405 Fatty acid desaturase 8 302 3.2E-75 T 14-10-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 A4R43_40735 dbb0b5cbbfbc83f8c33fda1dbc3f4a5d 310 SUPERFAMILY SSF53474 136 309 1.73E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40735 dbb0b5cbbfbc83f8c33fda1dbc3f4a5d 310 Gene3D G3DSA:3.40.50.1820 16 288 1.8E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40735 dbb0b5cbbfbc83f8c33fda1dbc3f4a5d 310 SUPERFAMILY SSF53474 17 125 2.6E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40735 dbb0b5cbbfbc83f8c33fda1dbc3f4a5d 310 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 41 251 3.0E-66 T 14-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 A4R43_40735 dbb0b5cbbfbc83f8c33fda1dbc3f4a5d 310 Pfam PF10503 Esterase PHB depolymerase 44 241 6.6E-35 T 14-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 A4R43_22200 a3d9d4e530550ebc891ffd3461147062 177 Gene3D G3DSA:3.40.630.30 6 176 8.7E-42 T 14-10-2018 A4R43_22200 a3d9d4e530550ebc891ffd3461147062 177 SUPERFAMILY SSF55729 14 161 3.96E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_22200 a3d9d4e530550ebc891ffd3461147062 177 Pfam PF13302 Acetyltransferase (GNAT) domain 21 160 1.7E-29 T 14-10-2018 IPR000182 GNAT domain A4R43_22800 cb69386a7f61812818597f0c74dd1bd6 352 SUPERFAMILY SSF53659 3 351 5.76E-117 T 14-10-2018 A4R43_22800 cb69386a7f61812818597f0c74dd1bd6 352 Gene3D G3DSA:3.40.718.10 1 352 1.1E-131 T 14-10-2018 A4R43_22800 cb69386a7f61812818597f0c74dd1bd6 352 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 346 7.9E-90 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_22800 cb69386a7f61812818597f0c74dd1bd6 352 SMART SM01329 5 347 1.2E-173 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_22800 cb69386a7f61812818597f0c74dd1bd6 352 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 240 259 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4R43_22800 cb69386a7f61812818597f0c74dd1bd6 352 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 351 7.6E-155 T 14-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 A4R43_18585 6a4be468d37c6aa95d1fc24cb78a8762 182 SUPERFAMILY SSF46689 2 62 1.23E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_18585 6a4be468d37c6aa95d1fc24cb78a8762 182 SUPERFAMILY SSF48498 68 172 1.01E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_18585 6a4be468d37c6aa95d1fc24cb78a8762 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 47 4.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_18585 6a4be468d37c6aa95d1fc24cb78a8762 182 Gene3D G3DSA:1.10.357.10 1 177 1.4E-46 T 14-10-2018 A4R43_11890 7b1df54ce391aabd262f9781bb2059bc 264 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 255 2.1E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4R43_11890 7b1df54ce391aabd262f9781bb2059bc 264 Gene3D G3DSA:3.40.50.300 6 257 4.2E-59 T 14-10-2018 A4R43_11890 7b1df54ce391aabd262f9781bb2059bc 264 SUPERFAMILY SSF52540 8 255 2.23E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11890 7b1df54ce391aabd262f9781bb2059bc 264 Pfam PF00005 ABC transporter 25 185 2.2E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_11890 7b1df54ce391aabd262f9781bb2059bc 264 SMART SM00382 34 232 4.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 PIRSF PIRSF004749 1 185 3.4E-45 T 14-10-2018 IPR023635 Peptide deformylase A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 Hamap MF_00163 Peptide deformylase [def]. 2 170 28.461 T 14-10-2018 IPR023635 Peptide deformylase A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 PRINTS PR01576 Peptide deformylase signature 109 127 1.1E-31 T 14-10-2018 IPR023635 Peptide deformylase A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 PRINTS PR01576 Peptide deformylase signature 128 157 1.1E-31 T 14-10-2018 IPR023635 Peptide deformylase A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 PRINTS PR01576 Peptide deformylase signature 97 108 1.1E-31 T 14-10-2018 IPR023635 Peptide deformylase A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 PRINTS PR01576 Peptide deformylase signature 33 62 1.1E-31 T 14-10-2018 IPR023635 Peptide deformylase A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 Gene3D G3DSA:3.90.45.10 1 189 1.6E-66 T 14-10-2018 IPR036821 Peptide deformylase superfamily A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 160 5.2E-39 T 14-10-2018 IPR023635 Peptide deformylase A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 Pfam PF01327 Polypeptide deformylase 4 156 2.2E-45 T 14-10-2018 IPR023635 Peptide deformylase A4R43_26125 28c8dd7443aaaa66b0bf0df511b52d31 189 SUPERFAMILY SSF56420 3 181 3.79E-54 T 14-10-2018 IPR036821 Peptide deformylase superfamily A4R43_20910 7d9ad895401834f236c95a9158160f29 503 Pfam PF00501 AMP-binding enzyme 8 403 6.8E-99 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_20910 7d9ad895401834f236c95a9158160f29 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 485 2.5E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_20910 7d9ad895401834f236c95a9158160f29 503 SUPERFAMILY SSF56801 3 497 1.26E-152 T 14-10-2018 A4R43_20910 7d9ad895401834f236c95a9158160f29 503 Gene3D G3DSA:3.30.300.310 399 498 5.2E-36 T 14-10-2018 A4R43_20910 7d9ad895401834f236c95a9158160f29 503 Gene3D G3DSA:3.40.50.12780 1 396 8.2E-118 T 14-10-2018 A4R43_19505 c9766a4bf169be78f2b02085b289f429 173 SUPERFAMILY SSF51161 3 145 1.29E-36 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_19505 c9766a4bf169be78f2b02085b289f429 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 1.0E-5 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_19505 c9766a4bf169be78f2b02085b289f429 173 Gene3D G3DSA:2.160.10.10 2 170 2.2E-45 T 14-10-2018 A4R43_22745 9632941672ebb909833916b55096d6ac 363 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 242 332 2.1E-11 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain A4R43_22745 9632941672ebb909833916b55096d6ac 363 Pfam PF13186 Iron-sulfur cluster-binding domain 239 305 6.1E-10 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain A4R43_22745 9632941672ebb909833916b55096d6ac 363 Pfam PF13353 4Fe-4S single cluster domain 16 118 9.7E-5 T 14-10-2018 A4R43_22745 9632941672ebb909833916b55096d6ac 363 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 7 342 7.5E-163 T 14-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 A4R43_22745 9632941672ebb909833916b55096d6ac 363 Pfam PF04055 Radical SAM superfamily 16 168 3.1E-22 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_22745 9632941672ebb909833916b55096d6ac 363 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 363 162.685 T 14-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 A4R43_22745 9632941672ebb909833916b55096d6ac 363 PIRSF PIRSF037420 2 347 3.2E-105 T 14-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A4R43_22745 9632941672ebb909833916b55096d6ac 363 Gene3D G3DSA:3.20.20.70 12 299 5.7E-47 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_22745 9632941672ebb909833916b55096d6ac 363 SUPERFAMILY SSF102114 8 314 9.55E-72 T 14-10-2018 A4R43_22745 9632941672ebb909833916b55096d6ac 363 SMART SM00729 10 218 9.1E-4 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_23125 0bfe67e524624d50d081fe6f80b13709 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 17.778 T 14-10-2018 IPR003482 Transcription factor WhiB A4R43_23125 0bfe67e524624d50d081fe6f80b13709 84 Pfam PF02467 Transcription factor WhiB 3 71 1.2E-25 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 412 3.1E-65 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 207 6.1E-18 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 PRINTS PR01042 Aspartyl-tRNA synthetase signature 178 190 6.1E-18 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 PRINTS PR01042 Aspartyl-tRNA synthetase signature 333 349 6.1E-18 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 PRINTS PR01042 Aspartyl-tRNA synthetase signature 373 387 6.1E-18 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 Pfam PF01336 OB-fold nucleic acid binding domain 18 88 7.8E-11 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 418 37.292 T 14-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 Gene3D G3DSA:2.40.50.140 4 94 9.2E-20 T 14-10-2018 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 Gene3D G3DSA:3.30.930.10 98 407 4.1E-86 T 14-10-2018 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 SUPERFAMILY SSF55681 95 417 2.16E-75 T 14-10-2018 A4R43_21110 b86b22c1af67a60b32d7e7f9211cda11 418 SUPERFAMILY SSF50249 10 96 6.29E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_15040 28dbd249ca936c09c0fb122853608740 554 Gene3D G3DSA:3.40.50.300 73 276 3.5E-6 T 14-10-2018 A4R43_15040 28dbd249ca936c09c0fb122853608740 554 SUPERFAMILY SSF52540 79 311 1.03E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09375 4dd9df68bcbc41beca030a8d68a4e730 313 Pfam PF01032 FecCD transport family 2 298 1.4E-56 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_09375 4dd9df68bcbc41beca030a8d68a4e730 313 Gene3D G3DSA:1.10.3470.10 1 312 5.2E-62 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_09375 4dd9df68bcbc41beca030a8d68a4e730 313 SUPERFAMILY SSF81345 5 298 4.18E-50 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_33130 b93c016377eccaaa3d2f5957a57b6435 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 2.1E-24 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A4R43_33130 b93c016377eccaaa3d2f5957a57b6435 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 20.226 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 A4R43_20380 b6f2bb24262db4475b6f3e4b1ea93a27 227 Gene3D G3DSA:1.10.10.10 3 106 3.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20380 b6f2bb24262db4475b6f3e4b1ea93a27 227 Pfam PF03551 Transcriptional regulator PadR-like family 14 89 1.4E-13 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_20380 b6f2bb24262db4475b6f3e4b1ea93a27 227 SUPERFAMILY SSF46785 10 181 1.06E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09230 043199fd63e4e03baa4bdab912a40ea6 118 SUPERFAMILY SSF56024 1 49 2.92E-9 T 14-10-2018 A4R43_09230 043199fd63e4e03baa4bdab912a40ea6 118 Gene3D G3DSA:3.30.870.10 1 50 7.6E-6 T 14-10-2018 A4R43_15325 6d7972009630c229b098425ca569cbc6 123 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 11 116 5.2E-23 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_15325 6d7972009630c229b098425ca569cbc6 123 SUPERFAMILY SSF50475 24 98 1.59E-6 T 14-10-2018 A4R43_15325 6d7972009630c229b098425ca569cbc6 123 Pfam PF04075 F420H(2)-dependent quinone reductase 7 118 1.7E-29 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_15325 6d7972009630c229b098425ca569cbc6 123 Gene3D G3DSA:2.30.110.10 7 106 1.9E-10 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_20585 f3c3da3c0777cc4a04ed1a6f216b9cc2 149 Pfam PF00582 Universal stress protein family 4 147 4.4E-28 T 14-10-2018 IPR006016 UspA A4R43_20585 f3c3da3c0777cc4a04ed1a6f216b9cc2 149 Gene3D G3DSA:3.40.50.620 1 149 8.5E-42 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_20585 f3c3da3c0777cc4a04ed1a6f216b9cc2 149 SUPERFAMILY SSF52402 2 147 2.01E-27 T 14-10-2018 A4R43_20585 f3c3da3c0777cc4a04ed1a6f216b9cc2 149 PRINTS PR01438 Universal stress protein signature 125 147 1.9E-16 T 14-10-2018 IPR006015 Universal stress protein A A4R43_20585 f3c3da3c0777cc4a04ed1a6f216b9cc2 149 PRINTS PR01438 Universal stress protein signature 107 119 1.9E-16 T 14-10-2018 IPR006015 Universal stress protein A A4R43_20585 f3c3da3c0777cc4a04ed1a6f216b9cc2 149 PRINTS PR01438 Universal stress protein signature 4 22 1.9E-16 T 14-10-2018 IPR006015 Universal stress protein A A4R43_33270 20a8c831595e19ec77827d9423fa671e 325 Gene3D G3DSA:2.120.10.30 172 322 2.4E-11 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_33270 20a8c831595e19ec77827d9423fa671e 325 SUPERFAMILY SSF69304 83 310 2.48E-11 T 14-10-2018 A4R43_17475 cc2f49bb4aeb6c6dde1f82f882b689ab 469 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 3 460 2.5E-92 T 14-10-2018 IPR007795 Type VII secretion system EccB A4R43_17475 cc2f49bb4aeb6c6dde1f82f882b689ab 469 Gene3D G3DSA:2.40.50.900 70 149 2.4E-23 T 14-10-2018 A4R43_17475 cc2f49bb4aeb6c6dde1f82f882b689ab 469 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 465 5.2E-92 T 14-10-2018 IPR007795 Type VII secretion system EccB A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 SUPERFAMILY SSF56003 71 266 5.58E-27 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 SMART SM01008 232 310 4.6E-17 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 SUPERFAMILY SSF56003 339 731 1.86E-85 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 Gene3D G3DSA:3.30.365.10 339 565 4.2E-38 T 14-10-2018 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 Gene3D G3DSA:3.90.1170.50 207 285 1.2E-10 T 14-10-2018 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 Gene3D G3DSA:3.30.365.10 577 735 8.8E-23 T 14-10-2018 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 75 206 6.7E-16 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 340 573 2.7E-24 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 608 680 7.7E-7 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 PIRSF PIRSF036389 11 737 2.1E-180 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 Gene3D G3DSA:3.30.365.10 67 206 1.4E-23 T 14-10-2018 A4R43_27700 499b249a376775c2b97e23703afdc7a0 742 Gene3D G3DSA:3.30.365.10 351 442 4.2E-38 T 14-10-2018 A4R43_23255 dcc138cd0a760ce52b00eab1f9d95046 522 PIRSF PIRSF006060 8 509 1.2E-91 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_23255 dcc138cd0a760ce52b00eab1f9d95046 522 Pfam PF13520 Amino acid permease 30 465 3.8E-51 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_23255 dcc138cd0a760ce52b00eab1f9d95046 522 Gene3D G3DSA:1.20.1740.10 25 502 1.7E-114 T 14-10-2018 A4R43_37675 e530859581a14a71cdb511c17dcf6ccc 227 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_37675 e530859581a14a71cdb511c17dcf6ccc 227 Gene3D G3DSA:3.40.50.300 5 225 3.9E-67 T 14-10-2018 A4R43_37675 e530859581a14a71cdb511c17dcf6ccc 227 Pfam PF00005 ABC transporter 24 172 6.4E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_37675 e530859581a14a71cdb511c17dcf6ccc 227 SMART SM00382 33 220 9.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_37675 e530859581a14a71cdb511c17dcf6ccc 227 SUPERFAMILY SSF52540 19 223 1.56E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37680 aab5bf46384b406e3f14c7b22eadaa41 406 Pfam PF02687 FtsX-like permease family 311 399 4.8E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_37680 aab5bf46384b406e3f14c7b22eadaa41 406 Pfam PF12704 MacB-like periplasmic core domain 37 247 1.4E-17 T 14-10-2018 IPR025857 MacB-like periplasmic core domain A4R43_29935 9afe90b642e5c701e87715c3a0c570e3 356 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 17 151 6.4E-43 T 14-10-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 A4R43_29935 9afe90b642e5c701e87715c3a0c570e3 356 Pfam PF16169 Domain of unknown function (DUF4872) 162 345 1.5E-46 T 14-10-2018 IPR032369 Domain of unknown function DUF4872 A4R43_40665 d56d8601663071da5a471c53916170fd 176 SUPERFAMILY SSF82607 25 98 1.11E-5 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_40665 d56d8601663071da5a471c53916170fd 176 Pfam PF02575 YbaB/EbfC DNA-binding family 25 99 2.3E-8 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_40665 d56d8601663071da5a471c53916170fd 176 Gene3D G3DSA:3.30.1310.10 19 106 1.3E-5 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_39625 3d0bd2dd8dbc56c6de190625b4df1a70 432 SUPERFAMILY SSF53383 16 424 1.05E-110 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_39625 3d0bd2dd8dbc56c6de190625b4df1a70 432 Pfam PF00202 Aminotransferase class-III 25 421 2.1E-92 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_39625 3d0bd2dd8dbc56c6de190625b4df1a70 432 Gene3D G3DSA:3.90.1150.10 5 420 9.6E-126 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_39625 3d0bd2dd8dbc56c6de190625b4df1a70 432 PIRSF PIRSF000521 22 130 2.6E-10 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_39625 3d0bd2dd8dbc56c6de190625b4df1a70 432 PIRSF PIRSF000521 126 427 6.1E-40 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_39625 3d0bd2dd8dbc56c6de190625b4df1a70 432 Gene3D G3DSA:3.40.640.10 60 324 9.6E-126 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_21770 586edb74a17c8ea6b8171577bbc25831 105 Pfam PF02575 YbaB/EbfC DNA-binding family 17 84 7.7E-7 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_21770 586edb74a17c8ea6b8171577bbc25831 105 SUPERFAMILY SSF82607 13 84 8.37E-5 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_25285 976bf7269d4e13d85ed602b01d064cac 237 Gene3D G3DSA:3.10.180.10 1 129 6.2E-36 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_25285 976bf7269d4e13d85ed602b01d064cac 237 SUPERFAMILY SSF54593 6 125 3.26E-13 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_03835 2582fc958caea1c3d7bd3189f85bf41f 526 Gene3D G3DSA:3.60.21.70 148 526 3.6E-137 T 14-10-2018 IPR038607 PhoD-like superfamily A4R43_03835 2582fc958caea1c3d7bd3189f85bf41f 526 Pfam PF09423 PhoD-like phosphatase 155 495 8.7E-110 T 14-10-2018 IPR018946 Alkaline phosphatase D-related A4R43_03835 2582fc958caea1c3d7bd3189f85bf41f 526 SUPERFAMILY SSF56300 149 498 3.37E-35 T 14-10-2018 A4R43_03835 2582fc958caea1c3d7bd3189f85bf41f 526 Gene3D G3DSA:2.60.40.380 35 145 2.1E-36 T 14-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 A4R43_03835 2582fc958caea1c3d7bd3189f85bf41f 526 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 44 142 7.3E-32 T 14-10-2018 IPR032093 Phospholipase D, N-terminal A4R43_37280 c35fa1d69c2dd036a49f7da43d72f9fb 447 SUPERFAMILY SSF52777 194 444 1.67E-38 T 14-10-2018 A4R43_37280 c35fa1d69c2dd036a49f7da43d72f9fb 447 Pfam PF00668 Condensation domain 6 339 6.4E-61 T 14-10-2018 IPR001242 Condensation domain A4R43_37280 c35fa1d69c2dd036a49f7da43d72f9fb 447 SUPERFAMILY SSF52777 4 207 1.67E-31 T 14-10-2018 A4R43_37280 c35fa1d69c2dd036a49f7da43d72f9fb 447 Gene3D G3DSA:3.30.559.30 193 447 3.5E-87 T 14-10-2018 A4R43_37280 c35fa1d69c2dd036a49f7da43d72f9fb 447 Gene3D G3DSA:3.30.559.10 28 384 3.5E-87 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4R43_11255 4f567536628a9a79ae6958b06731493b 154 SMART SM00240 72 122 2.8E-17 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4R43_11255 4f567536628a9a79ae6958b06731493b 154 SUPERFAMILY SSF49879 29 143 2.49E-32 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 A4R43_11255 4f567536628a9a79ae6958b06731493b 154 Gene3D G3DSA:2.60.200.20 20 148 1.2E-40 T 14-10-2018 A4R43_11255 4f567536628a9a79ae6958b06731493b 154 Pfam PF00498 FHA domain 74 136 6.6E-19 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 20 97 7.0E-14 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 49 66 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 SUPERFAMILY SSF53706 244 758 1.18E-76 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 122 134 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Gene3D G3DSA:3.40.50.740 503 720 4.4E-26 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Gene3D G3DSA:3.40.50.740 315 386 2.9E-18 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 108 146 2.1E-15 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Gene3D G3DSA:3.10.20.740 20 147 1.6E-30 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Gene3D G3DSA:3.30.70.20 159 241 2.1E-6 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 23 674 9.7E-161 T 14-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 170 180 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Gene3D G3DSA:3.40.228.10 387 482 2.9E-18 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 SMART SM00926 253 307 6.6E-4 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 SUPERFAMILY SSF54862 100 248 1.26E-29 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 SUPERFAMILY SSF54292 20 96 8.56E-16 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Gene3D G3DSA:2.20.25.90 255 306 5.0E-10 T 14-10-2018 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Pfam PF00384 Molybdopterin oxidoreductase 533 659 1.6E-7 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 Pfam PF00384 Molybdopterin oxidoreductase 310 455 4.9E-14 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33110 039d09fe902a5cc6e3fea5207ee2b138 820 SMART SM00929 107 147 1.7E-18 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_11885 cd946f77cc1ee3965e791e56fa3f7118 71 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 3.4E-5 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_11885 cd946f77cc1ee3965e791e56fa3f7118 71 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 3.4E-5 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_11885 cd946f77cc1ee3965e791e56fa3f7118 71 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 3.4E-5 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_11885 cd946f77cc1ee3965e791e56fa3f7118 71 SUPERFAMILY SSF54862 4 60 3.29E-8 T 14-10-2018 A4R43_11885 cd946f77cc1ee3965e791e56fa3f7118 71 Gene3D G3DSA:3.30.70.20 2 62 1.8E-13 T 14-10-2018 A4R43_11885 cd946f77cc1ee3965e791e56fa3f7118 71 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 11 58 1.5E-9 T 14-10-2018 A4R43_11025 c7feba29bd75a9f5aef8b99db3d96fb9 387 SUPERFAMILY SSF103473 4 378 4.58E-52 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_11025 c7feba29bd75a9f5aef8b99db3d96fb9 387 Pfam PF07690 Major Facilitator Superfamily 8 330 3.5E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_11025 c7feba29bd75a9f5aef8b99db3d96fb9 387 Gene3D G3DSA:1.20.1250.20 3 381 3.2E-45 T 14-10-2018 A4R43_23795 d2404679d58404dc71d80bf6956a560a 236 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 206 1.1E-7 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_23795 d2404679d58404dc71d80bf6956a560a 236 SUPERFAMILY SSF53681 149 206 2.94E-5 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_23795 d2404679d58404dc71d80bf6956a560a 236 Gene3D G3DSA:3.40.50.12500 1 234 6.4E-76 T 14-10-2018 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 Pfam PF01014 Uricase 9 132 2.2E-21 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 Pfam PF01014 Uricase 143 275 1.2E-33 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 Gene3D G3DSA:3.10.270.10 1 289 2.8E-109 T 14-10-2018 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 SUPERFAMILY SSF55620 5 135 1.38E-47 T 14-10-2018 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 PIRSF PIRSF000241 2 287 1.8E-100 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 ProSitePatterns PS00366 Uricase signature. 148 175 - T 14-10-2018 IPR019842 Uricase, conserved site GO:0004846|GO:0006144|GO:0055114 KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 TIGRFAM TIGR03383 urate_oxi: urate oxidase 6 280 3.4E-107 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 PRINTS PR00093 Uricase signature 11 22 1.4E-22 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 PRINTS PR00093 Uricase signature 148 164 1.4E-22 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 PRINTS PR00093 Uricase signature 50 64 1.4E-22 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 PRINTS PR00093 Uricase signature 164 176 1.4E-22 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 PRINTS PR00093 Uricase signature 86 99 1.4E-22 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 SUPERFAMILY SSF55620 139 282 1.42E-53 T 14-10-2018 A4R43_18575 6806b7567f7c815991a7c95779d7935f 290 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 178 280 7.0E-32 T 14-10-2018 A4R43_24980 02523f19213970d583feb2ef340f9bfe 345 SUPERFAMILY SSF51735 2 338 2.08E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_24980 02523f19213970d583feb2ef340f9bfe 345 Gene3D G3DSA:3.90.25.10 212 334 3.4E-40 T 14-10-2018 A4R43_24980 02523f19213970d583feb2ef340f9bfe 345 Gene3D G3DSA:3.40.50.720 162 327 3.4E-40 T 14-10-2018 A4R43_24980 02523f19213970d583feb2ef340f9bfe 345 Gene3D G3DSA:3.40.50.720 1 143 1.8E-29 T 14-10-2018 A4R43_24980 02523f19213970d583feb2ef340f9bfe 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 266 2.4E-43 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_03345 63310dff60cebaeda298a1256088bf4a 308 Gene3D G3DSA:1.10.10.10 1 90 2.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03345 63310dff60cebaeda298a1256088bf4a 308 SUPERFAMILY SSF53850 93 291 2.17E-37 T 14-10-2018 A4R43_03345 63310dff60cebaeda298a1256088bf4a 308 Gene3D G3DSA:3.40.190.10 170 272 1.4E-43 T 14-10-2018 A4R43_03345 63310dff60cebaeda298a1256088bf4a 308 Pfam PF03466 LysR substrate binding domain 90 294 1.5E-38 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_03345 63310dff60cebaeda298a1256088bf4a 308 SUPERFAMILY SSF46785 2 111 3.83E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03345 63310dff60cebaeda298a1256088bf4a 308 Gene3D G3DSA:3.40.190.10 94 282 1.4E-43 T 14-10-2018 A4R43_03345 63310dff60cebaeda298a1256088bf4a 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_25500 f596ea50561bf56ea17506a214c4221b 214 SUPERFAMILY SSF46689 29 89 1.5E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25500 f596ea50561bf56ea17506a214c4221b 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 77 4.2E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_25500 f596ea50561bf56ea17506a214c4221b 214 Gene3D G3DSA:1.10.357.10 16 213 9.6E-18 T 14-10-2018 A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 69 2.1E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 Gene3D G3DSA:1.10.10.10 8 76 6.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 SMART SM00345 15 76 4.3E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 SMART SM00895 101 228 5.0E-17 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.5E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.5E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 SUPERFAMILY SSF46785 5 80 5.32E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 Gene3D G3DSA:1.20.120.530 99 230 6.1E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 SUPERFAMILY SSF48008 99 232 4.97E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_29050 cdfde8a855a76e24feb48a0f313b2025 250 Pfam PF07729 FCD domain 101 225 1.4E-19 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_18765 9a6155ebf7c27ceb07dc805de4896fca 60 Pfam PF01783 Ribosomal L32p protein family 2 58 1.0E-22 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18765 9a6155ebf7c27ceb07dc805de4896fca 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 57 17.034 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_18765 9a6155ebf7c27ceb07dc805de4896fca 60 SUPERFAMILY SSF57829 2 58 5.74E-17 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4R43_18765 9a6155ebf7c27ceb07dc805de4896fca 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 58 7.7E-20 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_35570 51d21d7f6308b4ef5c53d6fa3027ede5 315 Gene3D G3DSA:3.90.550.10 1 298 7.4E-117 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35570 51d21d7f6308b4ef5c53d6fa3027ede5 315 SUPERFAMILY SSF53448 26 259 1.84E-57 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35570 51d21d7f6308b4ef5c53d6fa3027ede5 315 Pfam PF00535 Glycosyl transferase family 2 27 135 1.7E-13 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_01515 6b0584e2cbdb85b40535b82288147314 420 PIRSF PIRSF036794 5 410 5.2E-89 T 14-10-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type A4R43_01515 6b0584e2cbdb85b40535b82288147314 420 SUPERFAMILY SSF159501 9 405 3.14E-117 T 14-10-2018 A4R43_01515 6b0584e2cbdb85b40535b82288147314 420 Gene3D G3DSA:1.20.1440.30 136 261 1.9E-59 T 14-10-2018 A4R43_01515 6b0584e2cbdb85b40535b82288147314 420 Gene3D G3DSA:3.40.1660.10 11 398 1.9E-59 T 14-10-2018 A4R43_01515 6b0584e2cbdb85b40535b82288147314 420 Pfam PF05139 Erythromycin esterase 56 398 9.1E-108 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 A4R43_01515 6b0584e2cbdb85b40535b82288147314 420 Gene3D G3DSA:3.30.1870.10 58 135 1.9E-59 T 14-10-2018 A4R43_38550 ae258ba5bfba834a6fb6db57b76ea099 144 Pfam PF13411 MerR HTH family regulatory protein 3 64 3.6E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38550 ae258ba5bfba834a6fb6db57b76ea099 144 Gene3D G3DSA:1.10.1660.10 1 124 2.0E-27 T 14-10-2018 A4R43_38550 ae258ba5bfba834a6fb6db57b76ea099 144 SMART SM00422 1 70 5.2E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38550 ae258ba5bfba834a6fb6db57b76ea099 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.5E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38550 ae258ba5bfba834a6fb6db57b76ea099 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.5E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38550 ae258ba5bfba834a6fb6db57b76ea099 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.5E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38550 ae258ba5bfba834a6fb6db57b76ea099 144 SUPERFAMILY SSF46955 3 113 1.68E-25 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_19850 b70d4a18a91b7cb7e5fda3efcbdf5a09 93 Pfam PF02583 Metal-sensitive transcriptional repressor 7 88 6.3E-31 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A4R43_19850 b70d4a18a91b7cb7e5fda3efcbdf5a09 93 Gene3D G3DSA:1.20.58.1000 4 93 1.8E-34 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily A4R43_34665 21397cea41e85540f56e016110944f48 346 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 29 295 7.2E-67 T 14-10-2018 IPR005274 Inner membrane protein YhjD A4R43_34665 21397cea41e85540f56e016110944f48 346 Pfam PF03631 Virulence factor BrkB 43 296 5.2E-43 T 14-10-2018 IPR017039 Virulence factor BrkB A4R43_34665 21397cea41e85540f56e016110944f48 346 PIRSF PIRSF035875 12 313 7.4E-33 T 14-10-2018 IPR017039 Virulence factor BrkB A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 SMART SM00448 31 143 2.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 231 9.8E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 Gene3D G3DSA:3.40.50.12740 32 237 8.0E-51 T 14-10-2018 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 SUPERFAMILY SSF46894 171 237 4.76E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 SMART SM00421 174 231 2.4E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 6.9E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 6.9E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 6.9E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 SUPERFAMILY SSF52172 32 154 3.7E-25 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_13865 85878c70cacbd02bbfdcd0d42ae39e4a 238 Pfam PF00072 Response regulator receiver domain 33 136 7.5E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_34930 c55d0bf32f961cd9a98320869d53151a 150 Pfam PF03358 NADPH-dependent FMN reductase 39 111 5.2E-6 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4R43_34930 c55d0bf32f961cd9a98320869d53151a 150 SUPERFAMILY SSF52218 4 148 3.87E-25 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_34930 c55d0bf32f961cd9a98320869d53151a 150 Gene3D G3DSA:3.40.50.360 3 150 8.5E-19 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_21605 f300e8c31ca02551d6ee4de0532f112e 391 SUPERFAMILY SSF56601 41 363 8.64E-74 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_21605 f300e8c31ca02551d6ee4de0532f112e 391 Gene3D G3DSA:3.40.710.10 33 387 3.8E-98 T 14-10-2018 A4R43_21605 f300e8c31ca02551d6ee4de0532f112e 391 Pfam PF00144 Beta-lactamase 44 377 1.3E-55 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_22195 f8267a80d711d9b368cf73dbd98759b3 237 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 6 212 1.2E-23 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_22195 f8267a80d711d9b368cf73dbd98759b3 237 Pfam PF07398 MDMPI C-terminal domain 139 229 7.3E-14 T 14-10-2018 IPR010872 MDMPI C-terminal A4R43_22195 f8267a80d711d9b368cf73dbd98759b3 237 SUPERFAMILY SSF109854 5 133 2.56E-8 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_22195 f8267a80d711d9b368cf73dbd98759b3 237 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 126 2.5E-14 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_27060 d24b9b14d120978ceea0dffd939a8fe4 303 Gene3D G3DSA:1.10.10.10 3 85 1.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27060 d24b9b14d120978ceea0dffd939a8fe4 303 Pfam PF01380 SIS domain 134 262 5.0E-24 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_27060 d24b9b14d120978ceea0dffd939a8fe4 303 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 80 1.6E-17 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A4R43_27060 d24b9b14d120978ceea0dffd939a8fe4 303 SUPERFAMILY SSF46689 8 79 7.53E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_27060 d24b9b14d120978ceea0dffd939a8fe4 303 SUPERFAMILY SSF53697 104 287 1.75E-44 T 14-10-2018 A4R43_27060 d24b9b14d120978ceea0dffd939a8fe4 303 Gene3D G3DSA:3.40.50.10490 102 285 2.2E-47 T 14-10-2018 A4R43_40330 0f35380f88c013646cc0566f71e92974 112 Pfam PF13564 DoxX-like family 7 107 9.9E-18 T 14-10-2018 IPR032808 DoxX family A4R43_34835 0ec1d482a14e9a0a54631e67def57c43 288 Pfam PF00171 Aldehyde dehydrogenase family 30 255 7.2E-38 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_34835 0ec1d482a14e9a0a54631e67def57c43 288 Gene3D G3DSA:3.40.605.10 2 288 1.7E-53 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_34835 0ec1d482a14e9a0a54631e67def57c43 288 SUPERFAMILY SSF53720 6 254 6.41E-44 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_28790 664c5137bbef25d21dafed1193dab2fa 279 SMART SM00530 22 94 4.7E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_28790 664c5137bbef25d21dafed1193dab2fa 279 Gene3D G3DSA:1.10.260.40 28 95 1.6E-5 T 14-10-2018 A4R43_28790 664c5137bbef25d21dafed1193dab2fa 279 Gene3D G3DSA:3.30.450.180 116 277 4.3E-13 T 14-10-2018 A4R43_28790 664c5137bbef25d21dafed1193dab2fa 279 Pfam PF13560 Helix-turn-helix domain 18 97 4.9E-17 T 14-10-2018 A4R43_28790 664c5137bbef25d21dafed1193dab2fa 279 SUPERFAMILY SSF47413 41 93 1.16E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 Hamap MF_00384 Homoserine kinase [thrB]. 5 290 28.312 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 89 100 - T 14-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 TIGRFAM TIGR00191 thrB: homoserine kinase 3 264 2.6E-63 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 Gene3D G3DSA:3.30.70.890 161 274 1.1E-30 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 SUPERFAMILY SSF55060 164 268 8.63E-24 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 Pfam PF00288 GHMP kinases N terminal domain 82 142 3.7E-11 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 PIRSF PIRSF000676 1 291 1.2E-73 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 Gene3D G3DSA:3.30.230.10 1 160 4.2E-47 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 Pfam PF08544 GHMP kinases C terminal 220 262 2.7E-6 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 SUPERFAMILY SSF54211 4 151 4.63E-30 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 PRINTS PR00958 Homoserine kinase signature 245 260 1.3E-33 T 14-10-2018 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 PRINTS PR00958 Homoserine kinase signature 129 142 1.3E-33 T 14-10-2018 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 PRINTS PR00958 Homoserine kinase signature 168 185 1.3E-33 T 14-10-2018 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 PRINTS PR00958 Homoserine kinase signature 10 25 1.3E-33 T 14-10-2018 A4R43_22445 a8280826b17b3aaea21a6c36d9c53961 292 PRINTS PR00958 Homoserine kinase signature 96 111 1.3E-33 T 14-10-2018 A4R43_08180 fa5370ea385c737a3178355c99df1bc7 109 SUPERFAMILY SSF54909 1 91 7.67E-30 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_08180 fa5370ea385c737a3178355c99df1bc7 109 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 2.2E-20 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4R43_08180 fa5370ea385c737a3178355c99df1bc7 109 Gene3D G3DSA:3.30.70.100 3 97 2.3E-23 T 14-10-2018 A4R43_03730 61fcccddf7ea4604f3f0e4b8b53475ae 505 Pfam PF01565 FAD binding domain 51 190 4.0E-37 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_03730 61fcccddf7ea4604f3f0e4b8b53475ae 505 Pfam PF02913 FAD linked oxidases, C-terminal domain 231 490 7.8E-13 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_03730 61fcccddf7ea4604f3f0e4b8b53475ae 505 SUPERFAMILY SSF56176 5 231 4.58E-57 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_03730 61fcccddf7ea4604f3f0e4b8b53475ae 505 Gene3D G3DSA:3.30.465.40 9 237 8.7E-62 T 14-10-2018 A4R43_03730 61fcccddf7ea4604f3f0e4b8b53475ae 505 SUPERFAMILY SSF55103 238 492 1.16E-24 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_12810 3fad5ce93941ecc4587e7cd4c7905286 68 Gene3D G3DSA:1.10.1470.10 4 64 3.9E-5 T 14-10-2018 IPR036629 YjbJ superfamily A4R43_12810 3fad5ce93941ecc4587e7cd4c7905286 68 SUPERFAMILY SSF69047 5 62 1.7E-7 T 14-10-2018 IPR036629 YjbJ superfamily A4R43_12810 3fad5ce93941ecc4587e7cd4c7905286 68 Pfam PF05532 CsbD-like 5 56 2.8E-15 T 14-10-2018 IPR008462 CsbD-like domain A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 637 675 6.6E-5 T 14-10-2018 IPR006530 YD repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 743 782 2.0E-6 T 14-10-2018 IPR006530 YD repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 530 565 1.8E-6 T 14-10-2018 IPR006530 YD repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 594 632 0.0014 T 14-10-2018 IPR006530 YD repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 678 715 0.0011 T 14-10-2018 IPR006530 YD repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1175 1205 1.1E-6 T 14-10-2018 IPR006530 YD repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 847 886 2.5E-7 T 14-10-2018 IPR006530 YD repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 722 761 6.8E-6 T 14-10-2018 IPR006530 YD repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Gene3D G3DSA:2.180.10.10 885 1377 1.6E-44 T 14-10-2018 A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF03527 RHS protein 1278 1305 5.8E-7 T 14-10-2018 IPR001826 RHS protein A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Gene3D G3DSA:3.90.930.1 599 749 1.1E-12 T 14-10-2018 A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Gene3D G3DSA:1.10.287.1060 88 171 1.1E-5 T 14-10-2018 A4R43_15075 0e338de10627258de433a6a480318e1e 1537 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1303 1377 3.7E-23 T 14-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF05593 RHS Repeat 847 884 1.0E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF05593 RHS Repeat 1175 1204 4.6E-7 T 14-10-2018 IPR031325 RHS repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF05593 RHS Repeat 685 715 8.3E-5 T 14-10-2018 IPR031325 RHS repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF05593 RHS Repeat 636 672 1.3E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF05593 RHS Repeat 970 1006 9.9E-5 T 14-10-2018 IPR031325 RHS repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF05593 RHS Repeat 722 758 1.3E-4 T 14-10-2018 IPR031325 RHS repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF05593 RHS Repeat 743 779 1.7E-6 T 14-10-2018 IPR031325 RHS repeat A4R43_15075 0e338de10627258de433a6a480318e1e 1537 SUPERFAMILY SSF140453 88 161 1.19E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_15075 0e338de10627258de433a6a480318e1e 1537 PRINTS PR00394 RHS protein signature 1345 1364 2.4E-9 T 14-10-2018 IPR001826 RHS protein A4R43_15075 0e338de10627258de433a6a480318e1e 1537 PRINTS PR00394 RHS protein signature 1322 1342 2.4E-9 T 14-10-2018 IPR001826 RHS protein A4R43_15075 0e338de10627258de433a6a480318e1e 1537 Pfam PF14410 HNH/ENDO VII superfamily nuclease with conserved GHE residues 1455 1515 8.6E-8 T 14-10-2018 IPR026835 UPF0720 protein yqcG A4R43_27705 f831d9b60f87c4099818323ee3d80e87 150 SUPERFAMILY SSF54292 3 88 3.91E-23 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_27705 f831d9b60f87c4099818323ee3d80e87 150 SUPERFAMILY SSF47741 85 149 3.4E-29 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_27705 f831d9b60f87c4099818323ee3d80e87 150 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 69 5.9E-6 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_27705 f831d9b60f87c4099818323ee3d80e87 150 Gene3D G3DSA:3.10.20.30 2 75 3.3E-23 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_27705 f831d9b60f87c4099818323ee3d80e87 150 Pfam PF01799 [2Fe-2S] binding domain 74 145 3.1E-26 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_27705 f831d9b60f87c4099818323ee3d80e87 150 Gene3D G3DSA:1.10.150.120 76 150 2.6E-27 T 14-10-2018 A4R43_02635 7d37b738d616b1e451717cbad710f82d 153 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_02635 7d37b738d616b1e451717cbad710f82d 153 SUPERFAMILY SSF55811 5 98 1.25E-15 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_02635 7d37b738d616b1e451717cbad710f82d 153 Gene3D G3DSA:3.90.79.10 4 110 4.1E-14 T 14-10-2018 A4R43_02635 7d37b738d616b1e451717cbad710f82d 153 Pfam PF00293 NUDIX domain 9 103 1.1E-12 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_12665 ef5d63cade01efd8c20798df103ed505 85 Pfam PF00550 Phosphopantetheine attachment site 8 75 4.2E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_12665 ef5d63cade01efd8c20798df103ed505 85 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 36 75 8.0E-6 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A4R43_12665 ef5d63cade01efd8c20798df103ed505 85 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 15.465 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A4R43_12665 ef5d63cade01efd8c20798df103ed505 85 Gene3D G3DSA:1.10.1200.10 1 84 6.0E-25 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_12665 ef5d63cade01efd8c20798df103ed505 85 SUPERFAMILY SSF47336 1 78 2.75E-22 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_00890 bb7a48e00578870a57869694ed7e0ced 386 Gene3D G3DSA:3.50.50.60 11 370 4.9E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00890 bb7a48e00578870a57869694ed7e0ced 386 SUPERFAMILY SSF51905 10 374 4.1E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00890 bb7a48e00578870a57869694ed7e0ced 386 Pfam PF01266 FAD dependent oxidoreductase 11 362 2.8E-36 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_00890 bb7a48e00578870a57869694ed7e0ced 386 Gene3D G3DSA:3.30.9.10 67 329 4.9E-97 T 14-10-2018 A4R43_40120 9277184b7130d4b5fee8113c12e4f632 190 Gene3D G3DSA:1.10.10.60 2 54 9.7E-20 T 14-10-2018 A4R43_40120 9277184b7130d4b5fee8113c12e4f632 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40120 9277184b7130d4b5fee8113c12e4f632 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40120 9277184b7130d4b5fee8113c12e4f632 190 SUPERFAMILY SSF48498 74 181 1.08E-18 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_40120 9277184b7130d4b5fee8113c12e4f632 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 179 2.8E-21 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_40120 9277184b7130d4b5fee8113c12e4f632 190 SUPERFAMILY SSF46689 6 67 2.54E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_40120 9277184b7130d4b5fee8113c12e4f632 190 Gene3D G3DSA:1.10.357.10 55 190 7.8E-22 T 14-10-2018 A4R43_40120 9277184b7130d4b5fee8113c12e4f632 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 5.6E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 6.5E-53 T 14-10-2018 A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 6.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 6.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 Gene3D G3DSA:3.40.50.720 2 243 3.9E-71 T 14-10-2018 A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 SUPERFAMILY SSF51735 3 242 2.25E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 183 1.8E-6 T 14-10-2018 A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09160 14b5cebec79952b8fcdbc20702aa8611 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_20490 a861f04c37fec3ad92ae243217a4e1b9 121 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 7.7E-24 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A4R43_20490 a861f04c37fec3ad92ae243217a4e1b9 121 Pfam PF12823 Domain of unknown function (DUF3817) 8 93 3.4E-24 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A4R43_31130 349a37d9bf79b7ae0416a05bac35eb7d 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 55 3.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31130 349a37d9bf79b7ae0416a05bac35eb7d 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 9.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31130 349a37d9bf79b7ae0416a05bac35eb7d 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 9.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31130 349a37d9bf79b7ae0416a05bac35eb7d 184 SUPERFAMILY SSF46689 3 66 2.21E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31130 349a37d9bf79b7ae0416a05bac35eb7d 184 Gene3D G3DSA:1.10.357.10 1 183 4.9E-22 T 14-10-2018 A4R43_37425 606b1ec5dd462ebce4b2399fbe01acde 310 Gene3D G3DSA:2.60.120.200 112 310 1.2E-8 T 14-10-2018 A4R43_37425 606b1ec5dd462ebce4b2399fbe01acde 310 SUPERFAMILY SSF49899 34 306 1.27E-11 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_10470 9d44b0d9d440004ff23eeff8c54205d8 543 SUPERFAMILY SSF53649 270 506 8.18E-12 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A4R43_10470 9d44b0d9d440004ff23eeff8c54205d8 543 Gene3D G3DSA:3.40.720.10 232 512 5.1E-18 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A4R43_10790 16cc29528a62bf79974acb3281193513 172 Gene3D G3DSA:3.90.79.10 2 169 3.4E-42 T 14-10-2018 A4R43_10790 16cc29528a62bf79974acb3281193513 172 ProSitePatterns PS00893 Nudix box signature. 71 92 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_10790 16cc29528a62bf79974acb3281193513 172 Pfam PF00293 NUDIX domain 35 156 5.4E-17 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_10790 16cc29528a62bf79974acb3281193513 172 PIRSF PIRSF017340 1 170 3.3E-54 T 14-10-2018 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 A4R43_10790 16cc29528a62bf79974acb3281193513 172 SUPERFAMILY SSF55811 6 148 3.93E-33 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_20480 0700be41fd51909f160001a78cd53289 96 Gene3D G3DSA:3.30.70.930 1 96 4.6E-27 T 14-10-2018 IPR029756 MTH1187/YkoF-like A4R43_20480 0700be41fd51909f160001a78cd53289 96 Pfam PF01910 Thiamine-binding protein 3 91 4.1E-30 T 14-10-2018 IPR002767 Thiamine-binding protein A4R43_20480 0700be41fd51909f160001a78cd53289 96 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 9.5E-17 T 14-10-2018 IPR002767 Thiamine-binding protein A4R43_20480 0700be41fd51909f160001a78cd53289 96 SUPERFAMILY SSF89957 1 95 3.14E-29 T 14-10-2018 IPR029756 MTH1187/YkoF-like A4R43_25990 cb7d7484cfd2768704e4026a177d408c 214 SUPERFAMILY SSF161098 10 196 2.35E-35 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_25990 cb7d7484cfd2768704e4026a177d408c 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 208 1.1E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_25990 cb7d7484cfd2768704e4026a177d408c 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 105 2.6E-25 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_25990 cb7d7484cfd2768704e4026a177d408c 214 Gene3D G3DSA:1.10.3720.10 1 211 5.9E-44 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_02135 42aa781a75c6fc4ac2bd66f88bedf058 167 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 20 159 1.1E-19 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 A4R43_00825 b6fbeda27e07e03455669ba1aed527fc 147 Gene3D G3DSA:1.20.120.450 15 146 2.8E-25 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_00825 b6fbeda27e07e03455669ba1aed527fc 147 SUPERFAMILY SSF109854 7 142 5.34E-36 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_00825 b6fbeda27e07e03455669ba1aed527fc 147 Pfam PF04978 Protein of unknown function (DUF664) 21 143 1.2E-31 T 14-10-2018 IPR007061 Protein of unknown function DUF664 A4R43_01465 0261582f34b3ac757a6f81e7d3766227 269 Pfam PF03861 ANTAR domain 179 228 9.7E-18 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_01465 0261582f34b3ac757a6f81e7d3766227 269 SMART SM01012 173 228 1.2E-15 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_01465 0261582f34b3ac757a6f81e7d3766227 269 Gene3D G3DSA:1.10.10.10 177 236 1.0E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01465 0261582f34b3ac757a6f81e7d3766227 269 SUPERFAMILY SSF52172 156 228 3.38E-7 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_36175 49e2b2ec0a90eb8b5fbf8b97b79ca755 332 SUPERFAMILY SSF54001 203 317 3.04E-36 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_36175 49e2b2ec0a90eb8b5fbf8b97b79ca755 332 Gene3D G3DSA:3.90.1720.10 171 326 1.5E-42 T 14-10-2018 A4R43_36175 49e2b2ec0a90eb8b5fbf8b97b79ca755 332 Pfam PF00877 NlpC/P60 family 222 312 1.1E-24 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_14900 c6e7c968329761625e024bf6e83899cd 203 Gene3D G3DSA:1.10.10.10 146 203 2.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14900 c6e7c968329761625e024bf6e83899cd 203 PIRSF PIRSF036382 6 203 1.6E-72 T 14-10-2018 IPR008327 Signal transduction response regulator, antiterminator A4R43_14900 c6e7c968329761625e024bf6e83899cd 203 SMART SM01012 144 199 8.6E-26 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_14900 c6e7c968329761625e024bf6e83899cd 203 Gene3D G3DSA:3.40.50.2300 7 145 2.6E-37 T 14-10-2018 A4R43_14900 c6e7c968329761625e024bf6e83899cd 203 SUPERFAMILY SSF52172 15 199 4.55E-58 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_14900 c6e7c968329761625e024bf6e83899cd 203 SMART SM00448 17 128 1.1E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_14900 c6e7c968329761625e024bf6e83899cd 203 Pfam PF00072 Response regulator receiver domain 19 128 8.5E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_14900 c6e7c968329761625e024bf6e83899cd 203 Pfam PF03861 ANTAR domain 148 199 1.2E-21 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_39725 8afb9e0ef525952e06d5075efe43379a 242 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 23 240 2.1E-48 T 14-10-2018 IPR015402 Protein of unknown function DUF1980 A4R43_39725 8afb9e0ef525952e06d5075efe43379a 242 Pfam PF09323 Domain of unknown function (DUF1980) 8 105 5.8E-8 T 14-10-2018 IPR015402 Protein of unknown function DUF1980 A4R43_23665 675811d2c10759fce6ab759a8505e695 829 SUPERFAMILY SSF56091 503 740 1.15E-11 T 14-10-2018 A4R43_23665 675811d2c10759fce6ab759a8505e695 829 SUPERFAMILY SSF56300 147 405 1.73E-41 T 14-10-2018 A4R43_23665 675811d2c10759fce6ab759a8505e695 829 Gene3D G3DSA:3.40.50.300 1 170 4.4E-45 T 14-10-2018 A4R43_23665 675811d2c10759fce6ab759a8505e695 829 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 455 768 3.5E-148 T 14-10-2018 IPR032380 Polynucleotide kinase-phosphatase, ligase domain A4R43_23665 675811d2c10759fce6ab759a8505e695 829 SUPERFAMILY SSF52540 3 130 5.23E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23665 675811d2c10759fce6ab759a8505e695 829 Gene3D G3DSA:3.30.470.30 612 829 1.3E-75 T 14-10-2018 A4R43_23665 675811d2c10759fce6ab759a8505e695 829 Pfam PF13671 AAA domain 10 135 2.1E-22 T 14-10-2018 A4R43_23665 675811d2c10759fce6ab759a8505e695 829 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 1 829 0.0 T 14-10-2018 IPR024028 Polynucleotide kinase-phosphatase, bacterial A4R43_23665 675811d2c10759fce6ab759a8505e695 829 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 771 829 7.0E-31 T 14-10-2018 IPR032390 Polynucleotide kinase-phosphatase, C-terminal A4R43_23665 675811d2c10759fce6ab759a8505e695 829 Gene3D G3DSA:3.60.21.10 171 416 7.1E-72 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_23665 675811d2c10759fce6ab759a8505e695 829 Gene3D G3DSA:3.30.470.30 425 608 4.2E-70 T 14-10-2018 A4R43_23665 675811d2c10759fce6ab759a8505e695 829 Pfam PF00149 Calcineurin-like phosphoesterase 181 381 3.7E-12 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_18170 0acd58e03cfdb195e353af7e1911bc80 232 Gene3D G3DSA:1.10.150.240 22 86 1.1E-47 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_18170 0acd58e03cfdb195e353af7e1911bc80 232 Gene3D G3DSA:3.40.50.1000 8 217 1.1E-47 T 14-10-2018 IPR023214 HAD superfamily A4R43_18170 0acd58e03cfdb195e353af7e1911bc80 232 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 188 3.1E-13 T 14-10-2018 A4R43_18170 0acd58e03cfdb195e353af7e1911bc80 232 SUPERFAMILY SSF56784 5 225 1.04E-31 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 Gene3D G3DSA:3.30.420.40 6 325 4.2E-115 T 14-10-2018 A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 Pfam PF00814 Glycoprotease family 30 318 1.1E-96 T 14-10-2018 IPR000905 Gcp-like domain A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 324 4.8E-126 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 Gene3D G3DSA:3.30.420.40 136 305 4.2E-115 T 14-10-2018 A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 8.8E-52 T 14-10-2018 IPR017861 Kae1/TsaD family A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 83 103 8.8E-52 T 14-10-2018 IPR017861 Kae1/TsaD family A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 104 123 8.8E-52 T 14-10-2018 IPR017861 Kae1/TsaD family A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 138 150 8.8E-52 T 14-10-2018 IPR017861 Kae1/TsaD family A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 162 183 8.8E-52 T 14-10-2018 IPR017861 Kae1/TsaD family A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 275 284 8.8E-52 T 14-10-2018 IPR017861 Kae1/TsaD family A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 SUPERFAMILY SSF53067 5 320 5.4E-37 T 14-10-2018 A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 ProSitePatterns PS01016 Glycoprotease family signature. 103 123 - T 14-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 318 8.1E-97 T 14-10-2018 IPR017861 Kae1/TsaD family A4R43_34275 fa02b7622d6399aa4eff739b909ffa21 349 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 344 62.181 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 A4R43_02825 19d9fe60b6d124a70d521a7987bfd014 259 Pfam PF07398 MDMPI C-terminal domain 145 247 3.6E-15 T 14-10-2018 IPR010872 MDMPI C-terminal A4R43_02825 19d9fe60b6d124a70d521a7987bfd014 259 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 133 1.5E-15 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_02825 19d9fe60b6d124a70d521a7987bfd014 259 Gene3D G3DSA:1.20.120.450 1 136 2.8E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_02825 19d9fe60b6d124a70d521a7987bfd014 259 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 228 8.6E-21 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_02825 19d9fe60b6d124a70d521a7987bfd014 259 SUPERFAMILY SSF109854 2 139 4.76E-12 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_02570 79458d548e2727555c2e5fe4ef34c8f4 110 SUPERFAMILY SSF46955 25 95 9.16E-14 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_02570 79458d548e2727555c2e5fe4ef34c8f4 110 Pfam PF13411 MerR HTH family regulatory protein 25 89 4.5E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_02570 79458d548e2727555c2e5fe4ef34c8f4 110 SMART SM00422 25 93 3.2E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_02570 79458d548e2727555c2e5fe4ef34c8f4 110 Gene3D G3DSA:1.10.1660.10 16 110 4.6E-16 T 14-10-2018 A4R43_37185 cd42d7603907fe9d0e890b993d836852 240 SUPERFAMILY SSF53335 7 226 1.1E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_37185 cd42d7603907fe9d0e890b993d836852 240 Pfam PF08241 Methyltransferase domain 44 142 3.7E-22 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_23095 f9a1fbb59f001721aa3993092933e2e9 204 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 1.6E-56 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4R43_23095 f9a1fbb59f001721aa3993092933e2e9 204 Gene3D G3DSA:2.60.120.10 1 203 2.5E-68 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_23095 f9a1fbb59f001721aa3993092933e2e9 204 SUPERFAMILY SSF51182 1 197 1.97E-68 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_23095 f9a1fbb59f001721aa3993092933e2e9 204 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 177 1.0E-64 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4R43_35445 46a8091eb2e8a34ca802fb2bddf6cb09 379 Pfam PF00534 Glycosyl transferases group 1 194 347 9.9E-17 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_35445 46a8091eb2e8a34ca802fb2bddf6cb09 379 Gene3D G3DSA:3.40.50.2000 11 365 1.9E-55 T 14-10-2018 A4R43_35445 46a8091eb2e8a34ca802fb2bddf6cb09 379 SUPERFAMILY SSF53756 2 366 8.07E-66 T 14-10-2018 A4R43_35445 46a8091eb2e8a34ca802fb2bddf6cb09 379 Gene3D G3DSA:3.40.50.2000 169 349 1.9E-55 T 14-10-2018 A4R43_35445 46a8091eb2e8a34ca802fb2bddf6cb09 379 Pfam PF13439 Glycosyltransferase Family 4 13 173 8.9E-21 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_18635 028775d1bf818fd1f79e75bc2e1e2ff1 253 Gene3D G3DSA:3.30.450.40 83 253 3.5E-54 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_18635 028775d1bf818fd1f79e75bc2e1e2ff1 253 Pfam PF09339 IclR helix-turn-helix domain 13 63 2.1E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_18635 028775d1bf818fd1f79e75bc2e1e2ff1 253 Gene3D G3DSA:1.10.10.10 3 80 2.3E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18635 028775d1bf818fd1f79e75bc2e1e2ff1 253 SMART SM00346 11 98 3.5E-18 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_18635 028775d1bf818fd1f79e75bc2e1e2ff1 253 SUPERFAMILY SSF55781 68 250 5.36E-47 T 14-10-2018 A4R43_18635 028775d1bf818fd1f79e75bc2e1e2ff1 253 SUPERFAMILY SSF46785 11 80 1.37E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_18635 028775d1bf818fd1f79e75bc2e1e2ff1 253 Pfam PF01614 Bacterial transcriptional regulator 126 248 4.6E-28 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_20950 6cec26d9bb5402983b186e4fdcc3b83f 147 Gene3D G3DSA:3.30.450.30 10 135 7.3E-39 T 14-10-2018 A4R43_20950 6cec26d9bb5402983b186e4fdcc3b83f 147 SUPERFAMILY SSF103196 9 131 4.97E-28 T 14-10-2018 A4R43_20950 6cec26d9bb5402983b186e4fdcc3b83f 147 Pfam PF03259 Roadblock/LC7 domain 15 104 3.2E-18 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_20950 6cec26d9bb5402983b186e4fdcc3b83f 147 SMART SM00960 14 104 5.3E-27 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_24965 e691ee482a7cce001b77c7fb5d533207 207 Pfam PF08666 SAF domain 53 85 2.2E-4 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A4R43_24965 e691ee482a7cce001b77c7fb5d533207 207 SMART SM00858 50 110 9.5E-7 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A4R43_38445 f19f98e10c45cf8cd273ad3746695928 344 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 321 3.1E-120 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_38445 f19f98e10c45cf8cd273ad3746695928 344 Gene3D G3DSA:3.40.50.720 5 311 2.4E-132 T 14-10-2018 A4R43_38445 f19f98e10c45cf8cd273ad3746695928 344 SUPERFAMILY SSF51735 3 326 2.05E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38445 f19f98e10c45cf8cd273ad3746695928 344 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 331 50.18 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 A4R43_38445 f19f98e10c45cf8cd273ad3746695928 344 Gene3D G3DSA:3.90.25.10 195 323 2.4E-132 T 14-10-2018 A4R43_25660 bf36fcea91e6736ff234a8ed1771f3ac 275 SMART SM00382 25 203 7.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_25660 bf36fcea91e6736ff234a8ed1771f3ac 275 Gene3D G3DSA:3.40.50.300 1 232 1.8E-60 T 14-10-2018 A4R43_25660 bf36fcea91e6736ff234a8ed1771f3ac 275 Pfam PF00005 ABC transporter 17 154 5.3E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_25660 bf36fcea91e6736ff234a8ed1771f3ac 275 SUPERFAMILY SSF52540 2 223 8.81E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25660 bf36fcea91e6736ff234a8ed1771f3ac 275 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_32680 77b17509f95a416979723b4d5e9e5438 134 SMART SM00530 14 69 9.4E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_32680 77b17509f95a416979723b4d5e9e5438 134 Gene3D G3DSA:1.10.260.40 6 74 5.9E-18 T 14-10-2018 A4R43_32680 77b17509f95a416979723b4d5e9e5438 134 Pfam PF01381 Helix-turn-helix 15 67 4.8E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_32680 77b17509f95a416979723b4d5e9e5438 134 SUPERFAMILY SSF47413 8 71 5.35E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_11955 fdc3c55efce8f344155e8703bb46fd5f 343 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 91 254 2.5E-9 T 14-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal A4R43_11955 fdc3c55efce8f344155e8703bb46fd5f 343 Gene3D G3DSA:3.60.60.10 91 341 3.9E-31 T 14-10-2018 A4R43_11955 fdc3c55efce8f344155e8703bb46fd5f 343 SUPERFAMILY SSF56235 91 332 3.01E-20 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_19070 727f84a571f6f25d0532e9d83e4ad6c9 386 PIRSF PIRSF000138 19 386 1.1E-124 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 A4R43_19070 727f84a571f6f25d0532e9d83e4ad6c9 386 Pfam PF01070 FMN-dependent dehydrogenase 34 383 2.5E-125 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A4R43_19070 727f84a571f6f25d0532e9d83e4ad6c9 386 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 281 287 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 A4R43_19070 727f84a571f6f25d0532e9d83e4ad6c9 386 SUPERFAMILY SSF51395 29 381 7.94E-90 T 14-10-2018 A4R43_19070 727f84a571f6f25d0532e9d83e4ad6c9 386 Gene3D G3DSA:3.20.20.70 25 386 2.4E-132 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_38130 2d71c920764cc8f3042592f483f8702a 389 Gene3D G3DSA:3.40.50.720 6 168 1.9E-35 T 14-10-2018 A4R43_38130 2d71c920764cc8f3042592f483f8702a 389 SUPERFAMILY SSF51735 7 159 7.4E-14 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38130 2d71c920764cc8f3042592f483f8702a 389 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 8 136 5.3E-11 T 14-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A4R43_39955 c593a5338f1284e1e62e52e75d9f0b27 150 SUPERFAMILY SSF69118 13 145 1.96E-28 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_39955 c593a5338f1284e1e62e52e75d9f0b27 150 Gene3D G3DSA:1.20.1290.10 5 149 1.3E-33 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_39955 c593a5338f1284e1e62e52e75d9f0b27 150 Pfam PF02627 Carboxymuconolactone decarboxylase family 14 95 7.8E-10 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_32675 f11e55a614ac8804b378bc770e3259cb 381 TIGRFAM TIGR04188 methyltr_grsp: methyltransferase, ATP-grasp peptide maturase system 7 365 6.2E-116 T 14-10-2018 IPR026448 Methyltransferase, ATP-grasp peptide maturase system A4R43_32675 f11e55a614ac8804b378bc770e3259cb 381 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 92 211 6.6E-23 T 14-10-2018 A4R43_32675 f11e55a614ac8804b378bc770e3259cb 381 SUPERFAMILY SSF53335 5 212 1.11E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_08050 294b26ec103b648be3f60720ed1840e2 276 Gene3D G3DSA:3.40.50.1820 1 274 7.2E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08050 294b26ec103b648be3f60720ed1840e2 276 Pfam PF12697 Alpha/beta hydrolase family 12 267 2.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_08050 294b26ec103b648be3f60720ed1840e2 276 SUPERFAMILY SSF53474 3 273 3.84E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_33045 5bae530163869108033db6ab91fa012b 530 Gene3D G3DSA:1.10.390.60 255 464 2.1E-38 T 14-10-2018 A4R43_33045 5bae530163869108033db6ab91fa012b 530 Gene3D G3DSA:2.60.40.1730 47 231 6.8E-27 T 14-10-2018 A4R43_33045 5bae530163869108033db6ab91fa012b 530 SUPERFAMILY SSF63737 36 230 4.58E-34 T 14-10-2018 A4R43_33045 5bae530163869108033db6ab91fa012b 530 SUPERFAMILY SSF55486 256 469 2.49E-48 T 14-10-2018 A4R43_33045 5bae530163869108033db6ab91fa012b 530 Pfam PF01433 Peptidase family M1 domain 314 459 1.4E-26 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_33045 5bae530163869108033db6ab91fa012b 530 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 166 181 4.2E-13 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_33045 5bae530163869108033db6ab91fa012b 530 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 214 229 4.2E-13 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_33045 5bae530163869108033db6ab91fa012b 530 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 338 350 4.2E-13 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_33045 5bae530163869108033db6ab91fa012b 530 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 334 4.2E-13 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_15545 1344b34ab83c101aa56b328ceb477001 137 SMART SM00116 11 59 2.3E-5 T 14-10-2018 IPR000644 CBS domain A4R43_15545 1344b34ab83c101aa56b328ceb477001 137 SMART SM00116 77 124 1.3E-9 T 14-10-2018 IPR000644 CBS domain A4R43_15545 1344b34ab83c101aa56b328ceb477001 137 Pfam PF00571 CBS domain 77 124 1.0E-9 T 14-10-2018 IPR000644 CBS domain A4R43_15545 1344b34ab83c101aa56b328ceb477001 137 Pfam PF00571 CBS domain 4 57 7.0E-10 T 14-10-2018 IPR000644 CBS domain A4R43_15545 1344b34ab83c101aa56b328ceb477001 137 Gene3D G3DSA:3.10.580.10 1 126 3.0E-40 T 14-10-2018 A4R43_15545 1344b34ab83c101aa56b328ceb477001 137 SUPERFAMILY SSF54631 1 124 1.23E-30 T 14-10-2018 A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 SUPERFAMILY SSF52540 390 606 1.21E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 Gene3D G3DSA:3.40.50.300 616 815 6.7E-86 T 14-10-2018 A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 SMART SM00487 397 578 8.7E-30 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 Pfam PF12419 SNF2 Helicase protein 236 351 2.6E-29 T 14-10-2018 IPR022138 Helicase SWF/SNF-related A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 Pfam PF00271 Helicase conserved C-terminal domain 690 801 1.3E-17 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 Pfam PF00176 SNF2 family N-terminal domain 419 674 1.3E-52 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 Gene3D G3DSA:3.40.50.10810 402 607 1.4E-63 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 SMART SM00490 719 801 2.8E-24 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 Gene3D G3DSA:1.20.120.850 630 851 6.7E-86 T 14-10-2018 A4R43_16120 c9b8d470a9b0a8e901fb81537c08a9c5 858 SUPERFAMILY SSF52540 609 855 1.18E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_36575 e661461acbc613ce38e2a6e4433fd827 356 SUPERFAMILY SSF53822 66 347 1.24E-42 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_36575 e661461acbc613ce38e2a6e4433fd827 356 Gene3D G3DSA:3.40.50.2300 64 331 1.0E-56 T 14-10-2018 A4R43_36575 e661461acbc613ce38e2a6e4433fd827 356 SUPERFAMILY SSF47413 8 67 4.5E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_36575 e661461acbc613ce38e2a6e4433fd827 356 Gene3D G3DSA:1.10.260.40 2 63 8.1E-19 T 14-10-2018 A4R43_36575 e661461acbc613ce38e2a6e4433fd827 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 52 3.6E-10 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_36575 e661461acbc613ce38e2a6e4433fd827 356 SMART SM00354 8 79 1.7E-10 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_36575 e661461acbc613ce38e2a6e4433fd827 356 Pfam PF13377 Periplasmic binding protein-like domain 177 353 5.4E-37 T 14-10-2018 A4R43_36575 e661461acbc613ce38e2a6e4433fd827 356 Gene3D G3DSA:3.40.50.2300 169 314 1.0E-56 T 14-10-2018 A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 5.6E-5 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 99 107 5.6E-5 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 5.6E-5 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 283 3.2E-36 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 Gene3D G3DSA:3.50.50.100 6 367 1.3E-69 T 14-10-2018 A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 SUPERFAMILY SSF51905 143 303 9.54E-18 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 2.3E-8 T 14-10-2018 A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.3E-8 T 14-10-2018 A4R43_12830 614d023b620bbfca9ccc9fe3e4ef8e8c 390 SUPERFAMILY SSF51905 8 175 1.67E-30 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21730 ae35e85b620bb960108cbc1e8f890eb2 121 Pfam PF11774 Lsr2 1 102 2.0E-34 T 14-10-2018 IPR024412 Lsr2 A4R43_21730 ae35e85b620bb960108cbc1e8f890eb2 121 Gene3D G3DSA:3.30.60.230 1 52 4.5E-22 T 14-10-2018 A4R43_21730 ae35e85b620bb960108cbc1e8f890eb2 121 Gene3D G3DSA:1.20.890.50 71 110 2.3E-11 T 14-10-2018 A4R43_21730 ae35e85b620bb960108cbc1e8f890eb2 121 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 104 5.0E-18 T 14-10-2018 IPR024412 Lsr2 A4R43_06040 6d3ee4b7bf00981dffbfa24b97f74139 511 Pfam PF13556 PucR C-terminal helix-turn-helix domain 443 498 2.5E-23 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_06040 6d3ee4b7bf00981dffbfa24b97f74139 511 Pfam PF07905 Purine catabolism regulatory protein-like family 6 118 5.5E-19 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain A4R43_06040 6d3ee4b7bf00981dffbfa24b97f74139 511 Gene3D G3DSA:1.10.10.2840 374 504 5.3E-26 T 14-10-2018 A4R43_21880 a4ac8a5c0ead22f0ece9ae54f9dc6b06 513 Gene3D G3DSA:1.10.275.10 1 199 5.2E-66 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal A4R43_21880 a4ac8a5c0ead22f0ece9ae54f9dc6b06 513 SUPERFAMILY SSF48557 4 505 6.75E-183 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4R43_21880 a4ac8a5c0ead22f0ece9ae54f9dc6b06 513 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 7 510 1.7E-199 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21880 a4ac8a5c0ead22f0ece9ae54f9dc6b06 513 Pfam PF00221 Aromatic amino acid lyase 13 473 1.9E-181 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A4R43_21880 a4ac8a5c0ead22f0ece9ae54f9dc6b06 513 Gene3D G3DSA:1.20.200.10 200 512 3.9E-111 T 14-10-2018 A4R43_21880 a4ac8a5c0ead22f0ece9ae54f9dc6b06 513 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 141 157 - T 14-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 A4R43_21185 0086c8ff09c4259998343021ce46a672 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21185 0086c8ff09c4259998343021ce46a672 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21185 0086c8ff09c4259998343021ce46a672 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21185 0086c8ff09c4259998343021ce46a672 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.5E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_21185 0086c8ff09c4259998343021ce46a672 309 SUPERFAMILY SSF46785 2 85 3.24E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_21185 0086c8ff09c4259998343021ce46a672 309 SUPERFAMILY SSF53850 90 267 6.36E-25 T 14-10-2018 A4R43_21185 0086c8ff09c4259998343021ce46a672 309 Gene3D G3DSA:3.40.190.290 90 289 6.7E-33 T 14-10-2018 A4R43_21185 0086c8ff09c4259998343021ce46a672 309 Pfam PF03466 LysR substrate binding domain 88 270 1.9E-25 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_21185 0086c8ff09c4259998343021ce46a672 309 Gene3D G3DSA:1.10.10.10 1 86 3.4E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02245 fd2005569ab42f824467eb209a3377d5 338 Gene3D G3DSA:3.40.50.150 162 336 4.8E-43 T 14-10-2018 A4R43_02245 fd2005569ab42f824467eb209a3377d5 338 SUPERFAMILY SSF46785 16 81 5.44E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02245 fd2005569ab42f824467eb209a3377d5 338 Gene3D G3DSA:1.10.10.10 9 107 8.0E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02245 fd2005569ab42f824467eb209a3377d5 338 Pfam PF13649 Methyltransferase domain 164 258 6.2E-11 T 14-10-2018 A4R43_02245 fd2005569ab42f824467eb209a3377d5 338 SUPERFAMILY SSF53335 152 324 9.48E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_26455 f1b58d78d3dca5d4d9d6954e6bb369e2 184 SUPERFAMILY SSF52540 15 140 4.66E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26455 f1b58d78d3dca5d4d9d6954e6bb369e2 184 Gene3D G3DSA:3.40.50.300 6 173 4.0E-12 T 14-10-2018 A4R43_26455 f1b58d78d3dca5d4d9d6954e6bb369e2 184 Pfam PF13671 AAA domain 15 135 6.8E-11 T 14-10-2018 A4R43_00735 5d711d66eda17ad35011ddb8c2cb0457 125 Pfam PF13564 DoxX-like family 7 115 2.9E-23 T 14-10-2018 IPR032808 DoxX family A4R43_37015 c8feaa0f9a629c41c49b872f4774908e 226 Pfam PF01638 HxlR-like helix-turn-helix 17 102 1.5E-23 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_37015 c8feaa0f9a629c41c49b872f4774908e 226 Gene3D G3DSA:1.10.10.10 3 128 6.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37015 c8feaa0f9a629c41c49b872f4774908e 226 SUPERFAMILY SSF55718 113 212 7.3E-7 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_37015 c8feaa0f9a629c41c49b872f4774908e 226 SUPERFAMILY SSF46785 4 118 1.98E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_37015 c8feaa0f9a629c41c49b872f4774908e 226 Gene3D G3DSA:3.30.1050.10 129 213 2.3E-5 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_34130 3e8828a4d6f12100a9e5da05a3cbe568 98 SUPERFAMILY SSF47336 14 93 5.63E-12 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_34130 3e8828a4d6f12100a9e5da05a3cbe568 98 Gene3D G3DSA:1.10.1200.10 11 98 3.6E-10 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_34130 3e8828a4d6f12100a9e5da05a3cbe568 98 Pfam PF00550 Phosphopantetheine attachment site 18 80 5.1E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_30000 4d3f41d4b147fafab98423e555e7971d 332 Gene3D G3DSA:3.10.129.10 196 318 1.4E-22 T 14-10-2018 A4R43_30000 4d3f41d4b147fafab98423e555e7971d 332 Pfam PF01575 MaoC like domain 198 296 2.7E-4 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_30000 4d3f41d4b147fafab98423e555e7971d 332 Gene3D G3DSA:3.10.129.10 15 184 2.0E-40 T 14-10-2018 A4R43_30000 4d3f41d4b147fafab98423e555e7971d 332 SUPERFAMILY SSF54637 197 309 6.31E-15 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_30000 4d3f41d4b147fafab98423e555e7971d 332 Pfam PF13452 N-terminal half of MaoC dehydratase 22 165 7.5E-23 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 A4R43_30000 4d3f41d4b147fafab98423e555e7971d 332 SUPERFAMILY SSF54637 22 182 7.63E-21 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_24515 546436fc5067a86eedcaa7ed85f89691 682 Pfam PF00361 Proton-conducting membrane transporter 128 418 6.3E-45 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_15275 6c933fbfadde0153072de29dbce66141 277 SUPERFAMILY SSF53850 81 276 4.16E-20 T 14-10-2018 A4R43_15275 6c933fbfadde0153072de29dbce66141 277 Gene3D G3DSA:3.40.190.10 153 186 5.1E-20 T 14-10-2018 A4R43_15275 6c933fbfadde0153072de29dbce66141 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 4.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_15275 6c933fbfadde0153072de29dbce66141 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 4.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_15275 6c933fbfadde0153072de29dbce66141 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 4.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_15275 6c933fbfadde0153072de29dbce66141 277 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 57 1.6E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_15275 6c933fbfadde0153072de29dbce66141 277 Gene3D G3DSA:3.40.190.10 92 152 5.1E-20 T 14-10-2018 A4R43_15275 6c933fbfadde0153072de29dbce66141 277 SUPERFAMILY SSF46785 4 79 1.43E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15275 6c933fbfadde0153072de29dbce66141 277 Gene3D G3DSA:1.10.10.10 1 79 2.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15275 6c933fbfadde0153072de29dbce66141 277 Pfam PF03466 LysR substrate binding domain 79 276 2.2E-18 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_04370 b46c4fe6a7e1f5698038f09841dcd0bf 215 SMART SM00849 12 191 1.2E-31 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_04370 b46c4fe6a7e1f5698038f09841dcd0bf 215 SUPERFAMILY SSF56281 4 208 8.39E-47 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_04370 b46c4fe6a7e1f5698038f09841dcd0bf 215 Pfam PF00753 Metallo-beta-lactamase superfamily 11 191 1.4E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_04370 b46c4fe6a7e1f5698038f09841dcd0bf 215 Gene3D G3DSA:3.60.15.10 2 213 1.8E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_25390 18f4eba7355ad27000dfae5e89331efd 528 Gene3D G3DSA:3.20.20.140 55 486 1.2E-127 T 14-10-2018 A4R43_25390 18f4eba7355ad27000dfae5e89331efd 528 Pfam PF07969 Amidohydrolase family 45 525 1.5E-92 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_25390 18f4eba7355ad27000dfae5e89331efd 528 Gene3D G3DSA:3.10.310.70 73 188 1.2E-127 T 14-10-2018 A4R43_25390 18f4eba7355ad27000dfae5e89331efd 528 Gene3D G3DSA:2.30.40.10 9 502 1.2E-127 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25390 18f4eba7355ad27000dfae5e89331efd 528 SUPERFAMILY SSF51338 2 525 5.53E-15 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_25390 18f4eba7355ad27000dfae5e89331efd 528 SUPERFAMILY SSF51556 54 487 5.45E-34 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_36015 3597da95ab22d43443f5f3aacefb4a58 552 Pfam PF09972 Predicted membrane protein (DUF2207) 38 499 4.4E-46 T 14-10-2018 IPR018702 Protein of unknown function DUF2207, membrane A4R43_02260 b78458d070bf61140d758b070bee0b42 287 Pfam PF05373 L-proline 3-hydroxylase, C-terminal 204 284 6.7E-7 T 14-10-2018 IPR008035 L-proline 3-hydroxylase, C-terminal GO:0016706|GO:0055114 A4R43_02260 b78458d070bf61140d758b070bee0b42 287 Gene3D G3DSA:1.10.1720.10 208 285 1.8E-6 T 14-10-2018 IPR037037 L-proline 3-hydroxylase, C-terminal domain superfamily GO:0016706|GO:0055114 A4R43_02260 b78458d070bf61140d758b070bee0b42 287 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 41 180 3.5E-15 T 14-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 A4R43_02260 b78458d070bf61140d758b070bee0b42 287 SUPERFAMILY SSF51197 1 284 5.22E-41 T 14-10-2018 A4R43_02260 b78458d070bf61140d758b070bee0b42 287 Gene3D G3DSA:2.60.120.330 1 190 4.5E-45 T 14-10-2018 IPR027443 Isopenicillin N synthase-like A4R43_23135 6a984024e93cae7db7bb011246456cba 71 SUPERFAMILY SSF51230 4 71 1.3E-15 T 14-10-2018 IPR011053 Single hybrid motif A4R43_23135 6a984024e93cae7db7bb011246456cba 71 Pfam PF00364 Biotin-requiring enzyme 11 70 1.6E-12 T 14-10-2018 IPR000089 Biotin/lipoyl attachment A4R43_23135 6a984024e93cae7db7bb011246456cba 71 Gene3D G3DSA:2.40.50.100 1 70 1.2E-17 T 14-10-2018 A4R43_39800 1f2b53bf36c623750da5a4b846509f41 422 TIGRFAM TIGR00277 HDIG: HDIG domain 72 108 1.2E-7 T 14-10-2018 IPR006675 HDIG domain A4R43_39800 1f2b53bf36c623750da5a4b846509f41 422 Pfam PF01966 HD domain 71 215 7.9E-20 T 14-10-2018 IPR006674 HD domain A4R43_39800 1f2b53bf36c623750da5a4b846509f41 422 SMART SM00471 67 225 4.6E-13 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_39800 1f2b53bf36c623750da5a4b846509f41 422 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 1 418 31.192 T 14-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 A4R43_39800 1f2b53bf36c623750da5a4b846509f41 422 Pfam PF13286 Phosphohydrolase-associated domain 325 415 4.5E-21 T 14-10-2018 IPR026875 Phosphohydrolase-associated domain A4R43_39800 1f2b53bf36c623750da5a4b846509f41 422 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 30 414 5.1E-76 T 14-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 A4R43_39800 1f2b53bf36c623750da5a4b846509f41 422 SUPERFAMILY SSF109604 29 239 4.36E-55 T 14-10-2018 A4R43_06455 9fea35aa563def023323def3e3b331df 289 SUPERFAMILY SSF161098 22 289 1.78E-63 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06455 9fea35aa563def023323def3e3b331df 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 278 6.3E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_06455 9fea35aa563def023323def3e3b331df 289 Gene3D G3DSA:1.10.3720.10 17 280 3.1E-55 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_05430 da1f417e1f975bba25c72d2259191fa4 504 SMART SM00880 224 485 7.1E-62 T 14-10-2018 IPR007899 CHAD domain A4R43_05430 da1f417e1f975bba25c72d2259191fa4 504 Gene3D G3DSA:1.40.20.10 207 499 4.2E-62 T 14-10-2018 IPR038186 CHAD domain superfamily A4R43_05430 da1f417e1f975bba25c72d2259191fa4 504 SUPERFAMILY SSF55154 6 216 1.0E-39 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A4R43_05430 da1f417e1f975bba25c72d2259191fa4 504 SMART SM01118 6 205 1.7E-15 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A4R43_05430 da1f417e1f975bba25c72d2259191fa4 504 Gene3D G3DSA:2.40.320.10 5 205 1.5E-20 T 14-10-2018 A4R43_05430 da1f417e1f975bba25c72d2259191fa4 504 Pfam PF05235 CHAD domain 224 452 7.3E-55 T 14-10-2018 IPR007899 CHAD domain A4R43_05430 da1f417e1f975bba25c72d2259191fa4 504 Pfam PF01928 CYTH domain 7 197 2.3E-15 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A4R43_18210 77fe9c3acc28b94ce07dd0c1bc908af3 511 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 56 3.0E-9 T 14-10-2018 A4R43_18210 77fe9c3acc28b94ce07dd0c1bc908af3 511 SUPERFAMILY SSF51905 6 316 7.56E-30 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_39340 a4273d54669e1d02920b06f761e495a5 280 SUPERFAMILY SSF82549 3 277 1.44E-75 T 14-10-2018 A4R43_39340 a4273d54669e1d02920b06f761e495a5 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 277 6.8E-81 T 14-10-2018 IPR003797 DegV A4R43_39340 a4273d54669e1d02920b06f761e495a5 280 Gene3D G3DSA:3.40.50.10170 2 153 2.6E-43 T 14-10-2018 A4R43_39340 a4273d54669e1d02920b06f761e495a5 280 Gene3D G3DSA:3.30.1180.10 154 278 1.5E-39 T 14-10-2018 A4R43_39340 a4273d54669e1d02920b06f761e495a5 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 2.9E-85 T 14-10-2018 IPR003797 DegV A4R43_38070 3fedd548b27feeeff64f8fe9417a7a77 348 Pfam PF12833 Helix-turn-helix domain 265 342 5.7E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_38070 3fedd548b27feeeff64f8fe9417a7a77 348 SUPERFAMILY SSF46689 295 343 4.3E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38070 3fedd548b27feeeff64f8fe9417a7a77 348 SMART SM00342 259 341 3.7E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_38070 3fedd548b27feeeff64f8fe9417a7a77 348 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 36 216 5.5E-31 T 14-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal A4R43_38070 3fedd548b27feeeff64f8fe9417a7a77 348 Gene3D G3DSA:1.10.10.60 236 345 2.1E-21 T 14-10-2018 A4R43_11075 ecd3ee2cff5f6954aabf6679fd0479fc 154 Gene3D G3DSA:3.40.1280.10 1 154 1.2E-57 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_11075 ecd3ee2cff5f6954aabf6679fd0479fc 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 31.287 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 A4R43_11075 ecd3ee2cff5f6954aabf6679fd0479fc 154 PIRSF PIRSF029256 1 154 4.3E-58 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 A4R43_11075 ecd3ee2cff5f6954aabf6679fd0479fc 154 Pfam PF00588 SpoU rRNA Methylase family 3 142 6.8E-29 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4R43_11075 ecd3ee2cff5f6954aabf6679fd0479fc 154 SUPERFAMILY SSF75217 2 152 1.18E-40 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_29630 223bc35bdc8b423122867cfee371730a 214 Pfam PF01478 Type IV leader peptidase family 71 178 4.5E-8 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 199 204 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 Pfam PF02983 Alpha-lytic protease prodomain 97 151 1.9E-12 T 14-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 258 278 4.7E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 197 211 4.7E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 279 296 4.7E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 299 322 4.7E-31 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 SUPERFAMILY SSF50494 176 357 3.28E-33 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 308 319 - T 14-10-2018 IPR033116 Serine proteases, trypsin family, serine active site A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 Gene3D G3DSA:2.40.10.10 177 361 2.4E-64 T 14-10-2018 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 PIRSF PIRSF001134 1 366 1.7E-102 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11720 3ff3752f1dc2dad3d36a17741558f4db 366 Gene3D G3DSA:2.40.10.10 245 351 2.4E-64 T 14-10-2018 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00463 E-class P450 group I signature 385 408 5.5E-21 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00463 E-class P450 group I signature 239 256 5.5E-21 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00463 E-class P450 group I signature 26 45 5.5E-21 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00463 E-class P450 group I signature 375 385 5.5E-21 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00463 E-class P450 group I signature 340 364 5.5E-21 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00463 E-class P450 group I signature 259 285 5.5E-21 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 SUPERFAMILY SSF48264 3 436 1.57E-100 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 378 387 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 Pfam PF00067 Cytochrome P450 4 422 5.0E-69 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 Gene3D G3DSA:1.10.630.10 1 439 5.2E-117 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00385 P450 superfamily signature 376 385 1.9E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00385 P450 superfamily signature 302 313 1.9E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00385 P450 superfamily signature 250 267 1.9E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_00085 5f68516f027d71daa8b305455e3bd5de 441 PRINTS PR00385 P450 superfamily signature 385 396 1.9E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15175 1aa6defecfbc51b794ccd257c6f8369e 289 SUPERFAMILY SSF103481 184 286 1.02E-13 T 14-10-2018 A4R43_15175 1aa6defecfbc51b794ccd257c6f8369e 289 SUPERFAMILY SSF103481 51 141 7.06E-12 T 14-10-2018 A4R43_15175 1aa6defecfbc51b794ccd257c6f8369e 289 Pfam PF00892 EamA-like transporter family 16 138 2.9E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_15175 1aa6defecfbc51b794ccd257c6f8369e 289 Pfam PF00892 EamA-like transporter family 148 280 5.0E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_34720 1722ab2f0f3f9f7f473221d604a164f3 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 4.8E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_34720 1722ab2f0f3f9f7f473221d604a164f3 335 SUPERFAMILY SSF47413 4 59 3.94E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_34720 1722ab2f0f3f9f7f473221d604a164f3 335 Pfam PF13377 Periplasmic binding protein-like domain 178 329 5.7E-17 T 14-10-2018 A4R43_34720 1722ab2f0f3f9f7f473221d604a164f3 335 Gene3D G3DSA:3.40.50.2300 170 288 1.5E-34 T 14-10-2018 A4R43_34720 1722ab2f0f3f9f7f473221d604a164f3 335 Gene3D G3DSA:1.10.260.40 1 61 5.4E-19 T 14-10-2018 A4R43_34720 1722ab2f0f3f9f7f473221d604a164f3 335 SUPERFAMILY SSF53822 81 309 3.53E-25 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_34720 1722ab2f0f3f9f7f473221d604a164f3 335 SMART SM00354 1 74 5.5E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_34720 1722ab2f0f3f9f7f473221d604a164f3 335 Gene3D G3DSA:3.40.50.2300 91 322 1.5E-34 T 14-10-2018 A4R43_12010 c355759b48936f4d71a0451f7d526925 265 SUPERFAMILY SSF51658 3 262 5.63E-55 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_12010 c355759b48936f4d71a0451f7d526925 265 Pfam PF01261 Xylose isomerase-like TIM barrel 21 221 1.0E-29 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_12010 c355759b48936f4d71a0451f7d526925 265 Gene3D G3DSA:3.20.20.150 3 265 5.2E-61 T 14-10-2018 A4R43_17465 a59bc6839243b6f0484cf9930db762cd 263 Pfam PF00795 Carbon-nitrogen hydrolase 3 250 4.6E-34 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_17465 a59bc6839243b6f0484cf9930db762cd 263 SUPERFAMILY SSF56317 3 261 1.83E-57 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_17465 a59bc6839243b6f0484cf9930db762cd 263 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 14-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site A4R43_17465 a59bc6839243b6f0484cf9930db762cd 263 Gene3D G3DSA:3.60.110.10 2 263 1.8E-61 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_17685 e841284cefc3a121cbb691b80c8a0e8c 562 SUPERFAMILY SSF81342 23 303 2.67E-61 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4R43_17685 e841284cefc3a121cbb691b80c8a0e8c 562 Gene3D G3DSA:1.20.810.10 12 440 2.5E-93 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 A4R43_17685 e841284cefc3a121cbb691b80c8a0e8c 562 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 298 1.5E-61 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A4R43_19625 1d9f92c84410355022b75f964e480343 352 SUPERFAMILY SSF51445 45 343 8.1E-44 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_19625 1d9f92c84410355022b75f964e480343 352 ProSitePatterns PS01095 Chitinases family 18 active site. 160 168 - T 14-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A4R43_19625 1d9f92c84410355022b75f964e480343 352 SMART SM00636 46 335 0.0011 T 14-10-2018 IPR011583 Chitinase II GO:0008061 A4R43_19625 1d9f92c84410355022b75f964e480343 352 Pfam PF00704 Glycosyl hydrolases family 18 48 261 1.6E-19 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A4R43_19625 1d9f92c84410355022b75f964e480343 352 Gene3D G3DSA:3.20.20.80 43 351 1.5E-55 T 14-10-2018 A4R43_22330 a3c8df78bdb3cd1caa7d24bbe6efa8eb 192 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 179 3.2E-52 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4R43_22330 a3c8df78bdb3cd1caa7d24bbe6efa8eb 192 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 184 6.0E-58 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4R43_22330 a3c8df78bdb3cd1caa7d24bbe6efa8eb 192 SUPERFAMILY SSF89028 7 184 3.14E-57 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4R43_22330 a3c8df78bdb3cd1caa7d24bbe6efa8eb 192 Pfam PF01923 Cobalamin adenosyltransferase 8 175 9.4E-56 T 14-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4R43_22330 a3c8df78bdb3cd1caa7d24bbe6efa8eb 192 Gene3D G3DSA:1.20.1200.10 29 192 4.5E-58 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4R43_13750 6638cbb9c9f97ab4ee7d9bfab1b3bcec 204 Pfam PF13302 Acetyltransferase (GNAT) domain 37 173 2.2E-17 T 14-10-2018 IPR000182 GNAT domain A4R43_13750 6638cbb9c9f97ab4ee7d9bfab1b3bcec 204 Gene3D G3DSA:3.40.630.30 22 203 2.8E-40 T 14-10-2018 A4R43_13750 6638cbb9c9f97ab4ee7d9bfab1b3bcec 204 SUPERFAMILY SSF55729 32 197 6.83E-37 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_39310 bd43da910d62e02f22c33bb15d68ef3f 424 SUPERFAMILY SSF103473 15 419 3.01E-67 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_39310 bd43da910d62e02f22c33bb15d68ef3f 424 Pfam PF00083 Sugar (and other) transporter 18 423 2.5E-27 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_39310 bd43da910d62e02f22c33bb15d68ef3f 424 Gene3D G3DSA:1.20.1250.20 14 424 7.6E-69 T 14-10-2018 A4R43_39310 bd43da910d62e02f22c33bb15d68ef3f 424 ProSitePatterns PS00216 Sugar transport proteins signature 1. 293 310 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_10330 afb8735a6540cd982189e5dd5ca5c351 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 6.6E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_10330 afb8735a6540cd982189e5dd5ca5c351 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 6.6E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_10330 afb8735a6540cd982189e5dd5ca5c351 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 6.6E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_10330 afb8735a6540cd982189e5dd5ca5c351 163 SUPERFAMILY SSF46785 12 151 4.63E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_10330 afb8735a6540cd982189e5dd5ca5c351 163 SMART SM00347 38 136 2.9E-22 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_10330 afb8735a6540cd982189e5dd5ca5c351 163 Pfam PF01047 MarR family 45 103 3.8E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_10330 afb8735a6540cd982189e5dd5ca5c351 163 Gene3D G3DSA:1.10.10.10 10 151 2.1E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 489 2.8E-115 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 9 498 34.157 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 344 351 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 SUPERFAMILY SSF52949 22 159 2.94E-28 T 14-10-2018 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 25 146 4.6E-26 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 SUPERFAMILY SSF53187 178 496 2.51E-107 T 14-10-2018 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 Gene3D G3DSA:3.40.220.10 10 159 2.6E-27 T 14-10-2018 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 PRINTS PR00481 Cytosol aminopeptidase signature 259 276 1.1E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 PRINTS PR00481 Cytosol aminopeptidase signature 318 339 1.1E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 PRINTS PR00481 Cytosol aminopeptidase signature 340 360 1.1E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 PRINTS PR00481 Cytosol aminopeptidase signature 281 302 1.1E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 PRINTS PR00481 Cytosol aminopeptidase signature 368 383 1.1E-47 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4R43_17805 f2ead5dc0cf83a9e6e76fa0821682d88 500 Gene3D G3DSA:3.40.630.10 164 499 5.2E-128 T 14-10-2018 A4R43_32370 6cbbe4994bc1d3d0be27203d51480ae6 241 Gene3D G3DSA:3.40.630.30 14 152 7.9E-27 T 14-10-2018 A4R43_32370 6cbbe4994bc1d3d0be27203d51480ae6 241 SUPERFAMILY SSF55729 13 212 2.84E-39 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_32370 6cbbe4994bc1d3d0be27203d51480ae6 241 Pfam PF13444 Acetyltransferase (GNAT) domain 31 125 1.7E-27 T 14-10-2018 A4R43_01535 20337ea9e0db7885cb1c1139f470a9d8 196 SMART SM00947 26 187 2.3E-56 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_01535 20337ea9e0db7885cb1c1139f470a9d8 196 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_01535 20337ea9e0db7885cb1c1139f470a9d8 196 Pfam PF00484 Carbonic anhydrase 34 183 6.8E-43 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_01535 20337ea9e0db7885cb1c1139f470a9d8 196 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 38 45 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_01535 20337ea9e0db7885cb1c1139f470a9d8 196 Gene3D G3DSA:3.40.1050.10 1 196 1.2E-60 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A4R43_01535 20337ea9e0db7885cb1c1139f470a9d8 196 SUPERFAMILY SSF53056 2 194 1.7E-55 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A4R43_32230 2e938abe1bfe54b59ac645f6caea5a36 381 Gene3D G3DSA:1.10.1200.80 269 335 4.3E-10 T 14-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 A4R43_32230 2e938abe1bfe54b59ac645f6caea5a36 381 Pfam PF01207 Dihydrouridine synthase (Dus) 25 328 1.1E-99 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4R43_32230 2e938abe1bfe54b59ac645f6caea5a36 381 SUPERFAMILY SSF51395 22 332 2.93E-78 T 14-10-2018 A4R43_32230 2e938abe1bfe54b59ac645f6caea5a36 381 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 15 336 9.4E-117 T 14-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 A4R43_32230 2e938abe1bfe54b59ac645f6caea5a36 381 Gene3D G3DSA:3.20.20.70 19 264 1.4E-74 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_32230 2e938abe1bfe54b59ac645f6caea5a36 381 PIRSF PIRSF006621 12 346 3.0E-107 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4R43_33690 23bc824c67ea9ea795f34c19ad37ffe6 259 Gene3D G3DSA:3.30.1380.10 31 255 1.3E-70 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_33690 23bc824c67ea9ea795f34c19ad37ffe6 259 Pfam PF01427 D-ala-D-ala dipeptidase 187 254 6.1E-16 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4R43_33690 23bc824c67ea9ea795f34c19ad37ffe6 259 Pfam PF01427 D-ala-D-ala dipeptidase 34 156 6.4E-16 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4R43_33690 23bc824c67ea9ea795f34c19ad37ffe6 259 SUPERFAMILY SSF55166 32 254 9.81E-61 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_33690 23bc824c67ea9ea795f34c19ad37ffe6 259 PIRSF PIRSF026671 8 259 1.5E-68 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4R43_33690 23bc824c67ea9ea795f34c19ad37ffe6 259 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 33 253 32.156 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4R43_23780 5073250d6d05d4d1530283bd56aaef71 144 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 6 144 1.0E-55 T 14-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 A4R43_23780 5073250d6d05d4d1530283bd56aaef71 144 SMART SM00422 7 75 5.8E-23 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23780 5073250d6d05d4d1530283bd56aaef71 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 4.6E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23780 5073250d6d05d4d1530283bd56aaef71 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 4.6E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23780 5073250d6d05d4d1530283bd56aaef71 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 4.6E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23780 5073250d6d05d4d1530283bd56aaef71 144 Gene3D G3DSA:1.10.1660.10 2 130 5.0E-34 T 14-10-2018 A4R43_23780 5073250d6d05d4d1530283bd56aaef71 144 Pfam PF13411 MerR HTH family regulatory protein 8 73 9.5E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_23780 5073250d6d05d4d1530283bd56aaef71 144 SUPERFAMILY SSF46955 7 129 6.23E-28 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 SUPERFAMILY SSF51905 6 366 4.84E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 Gene3D G3DSA:3.50.50.60 6 337 3.0E-99 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 Gene3D G3DSA:3.40.30.120 367 429 2.0E-10 T 14-10-2018 A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 Gene3D G3DSA:3.30.9.50 72 275 3.0E-99 T 14-10-2018 A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 329 3.4E-38 T 14-10-2018 A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 3.4E-38 T 14-10-2018 A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 3.4E-38 T 14-10-2018 A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 3.4E-38 T 14-10-2018 A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 3.4E-38 T 14-10-2018 A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 3.4E-38 T 14-10-2018 A4R43_36495 c8f4b5b8a4378ea3ee7be748ed707d27 462 Pfam PF01494 FAD binding domain 5 343 4.5E-84 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 SUPERFAMILY SSF81593 323 478 1.41E-36 T 14-10-2018 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 SUPERFAMILY SSF81301 554 826 1.63E-66 T 14-10-2018 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Pfam PF08335 GlnD PII-uridylyltransferase 332 477 3.1E-34 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Pfam PF08335 GlnD PII-uridylyltransferase 840 983 3.8E-17 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Gene3D G3DSA:1.20.120.330 323 479 1.7E-41 T 14-10-2018 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Gene3D G3DSA:1.20.120.330 829 985 1.2E-32 T 14-10-2018 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 87 307 5.9E-35 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 582 816 6.8E-60 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Gene3D G3DSA:3.30.460.100 591 823 1.1E-60 T 14-10-2018 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Gene3D G3DSA:3.30.460.100 95 315 2.7E-53 T 14-10-2018 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 SUPERFAMILY SSF81593 830 984 4.24E-34 T 14-10-2018 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 83 974 16.531 T 14-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 A4R43_22115 7eeb4b5e7a57a4bdf885078e9151cfea 986 SUPERFAMILY SSF81301 71 317 6.65E-55 T 14-10-2018 A4R43_29580 a264fef842b6bbd5b85d537399333c10 187 Gene3D G3DSA:3.40.50.2020 15 176 1.5E-27 T 14-10-2018 A4R43_29580 a264fef842b6bbd5b85d537399333c10 187 Pfam PF00156 Phosphoribosyl transferase domain 24 172 3.3E-14 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4R43_29580 a264fef842b6bbd5b85d537399333c10 187 SUPERFAMILY SSF53271 8 163 8.8E-15 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_25260 8e4b6d15929426a165f3e7c164b807dc 307 SMART SM00829 11 304 1.1E-34 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_25260 8e4b6d15929426a165f3e7c164b807dc 307 Pfam PF13602 Zinc-binding dehydrogenase 199 303 6.2E-17 T 14-10-2018 A4R43_25260 8e4b6d15929426a165f3e7c164b807dc 307 Gene3D G3DSA:3.90.180.10 9 303 3.6E-79 T 14-10-2018 A4R43_25260 8e4b6d15929426a165f3e7c164b807dc 307 SUPERFAMILY SSF51735 115 244 3.29E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_25260 8e4b6d15929426a165f3e7c164b807dc 307 Gene3D G3DSA:3.40.50.720 126 255 3.6E-79 T 14-10-2018 A4R43_25260 8e4b6d15929426a165f3e7c164b807dc 307 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 1.8E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_25260 8e4b6d15929426a165f3e7c164b807dc 307 SUPERFAMILY SSF50129 2 147 1.03E-36 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_35745 48fd1ea929da338c1fac023f650a33d0 123 Gene3D G3DSA:3.10.180.10 1 123 5.6E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_35745 48fd1ea929da338c1fac023f650a33d0 123 SUPERFAMILY SSF54593 7 122 4.38E-9 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_26990 725982d066a7ea487010a2cef6914e57 764 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 22 714 1.6E-207 T 14-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A4R43_26990 725982d066a7ea487010a2cef6914e57 764 PIRSF PIRSF001265 13 722 1.7E-250 T 14-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A4R43_26990 725982d066a7ea487010a2cef6914e57 764 Pfam PF03030 Inorganic H+ pyrophosphatase 29 708 5.3E-242 T 14-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A4R43_26990 725982d066a7ea487010a2cef6914e57 764 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 17 713 24.346 T 14-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A4R43_23885 e781ae7b605c5de3cdff08ad2c7dedeb 308 Gene3D G3DSA:1.10.3720.10 85 300 8.5E-19 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23885 e781ae7b605c5de3cdff08ad2c7dedeb 308 SUPERFAMILY SSF161098 90 294 2.09E-15 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23885 e781ae7b605c5de3cdff08ad2c7dedeb 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 1.7E-34 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_31110 df7c887dc34b23febc36b1ef8c50dd05 200 Pfam PF02036 SCP-2 sterol transfer family 92 192 2.4E-11 T 14-10-2018 IPR003033 SCP2 sterol-binding domain A4R43_31110 df7c887dc34b23febc36b1ef8c50dd05 200 Gene3D G3DSA:3.30.1050.10 73 198 6.2E-20 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_31110 df7c887dc34b23febc36b1ef8c50dd05 200 SUPERFAMILY SSF55718 81 195 3.53E-20 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_32125 1fd7115aadb9a8c2af146a45493b522a 160 SUPERFAMILY SSF47413 15 80 3.1E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_32125 1fd7115aadb9a8c2af146a45493b522a 160 Pfam PF13560 Helix-turn-helix domain 17 80 7.8E-12 T 14-10-2018 A4R43_32125 1fd7115aadb9a8c2af146a45493b522a 160 Gene3D G3DSA:1.10.260.40 11 80 1.5E-14 T 14-10-2018 A4R43_32125 1fd7115aadb9a8c2af146a45493b522a 160 SMART SM00530 21 78 7.3E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_07850 f3e969a3d6a68208324e8eb6eab75a2e 432 Pfam PF14751 Domain of unknown function (DUF4474) 227 407 1.3E-9 T 14-10-2018 IPR029322 Domain of unknown function DUF4474 A4R43_07850 f3e969a3d6a68208324e8eb6eab75a2e 432 Gene3D G3DSA:1.10.287.1060 14 103 6.2E-5 T 14-10-2018 A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 Gene3D G3DSA:2.40.10.10 276 379 5.0E-23 T 14-10-2018 A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 Gene3D G3DSA:2.40.10.10 184 275 1.7E-20 T 14-10-2018 A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 Pfam PF02674 Colicin V production protein 4 146 6.3E-14 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 SUPERFAMILY SSF50494 191 372 2.1E-38 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 9.2E-12 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 PRINTS PR00834 HtrA/DegQ protease family signature 284 308 9.2E-12 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 PRINTS PR00834 HtrA/DegQ protease family signature 324 341 9.2E-12 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 PRINTS PR00834 HtrA/DegQ protease family signature 225 237 9.2E-12 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4R43_27145 71d52d4c82b7062ec0497628d1851c39 394 Pfam PF13365 Trypsin-like peptidase domain 217 353 3.9E-25 T 14-10-2018 A4R43_00345 734b22b387ae95273a9be4e717551ea1 218 Gene3D G3DSA:3.40.50.2300 1 115 3.2E-27 T 14-10-2018 A4R43_00345 734b22b387ae95273a9be4e717551ea1 218 SUPERFAMILY SSF52172 1 114 5.27E-29 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_00345 734b22b387ae95273a9be4e717551ea1 218 Gene3D G3DSA:1.10.10.10 116 215 2.3E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00345 734b22b387ae95273a9be4e717551ea1 218 Pfam PF00072 Response regulator receiver domain 1 108 4.8E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_00345 734b22b387ae95273a9be4e717551ea1 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 213 1.7E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_00345 734b22b387ae95273a9be4e717551ea1 218 SUPERFAMILY SSF46894 114 214 3.4E-24 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_00345 734b22b387ae95273a9be4e717551ea1 218 SMART SM00862 141 213 8.0E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_00345 734b22b387ae95273a9be4e717551ea1 218 SMART SM00448 1 108 2.2E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_01835 e484b75cf1a0df4fd2d2de063696523f 445 Gene3D G3DSA:3.40.50.11450 1 437 2.7E-108 T 14-10-2018 A4R43_01835 e484b75cf1a0df4fd2d2de063696523f 445 Pfam PF06722 Protein of unknown function (DUF1205) 209 304 4.1E-20 T 14-10-2018 IPR010610 Domain of unknown function DUF1205 A4R43_01835 e484b75cf1a0df4fd2d2de063696523f 445 SUPERFAMILY SSF53756 1 441 1.67E-61 T 14-10-2018 A4R43_01835 e484b75cf1a0df4fd2d2de063696523f 445 Gene3D G3DSA:3.40.50.2000 232 424 2.7E-108 T 14-10-2018 A4R43_12735 6ffce3fcc8dadd50fc1174a41ddc4722 397 Pfam PF13556 PucR C-terminal helix-turn-helix domain 333 389 1.9E-16 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_12735 6ffce3fcc8dadd50fc1174a41ddc4722 397 Gene3D G3DSA:1.10.10.2840 265 393 1.1E-22 T 14-10-2018 A4R43_30560 fa34621d382efdd50267f3c37cabf25a 361 Gene3D G3DSA:1.10.4080.10 5 347 6.7E-64 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_30560 fa34621d382efdd50267f3c37cabf25a 361 SUPERFAMILY SSF101478 3 339 7.98E-53 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_30560 fa34621d382efdd50267f3c37cabf25a 361 Pfam PF03747 ADP-ribosylglycohydrolase 9 319 8.5E-60 T 14-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 A4R43_39770 38496f20c0f7fe4076fd429b06036003 246 Pfam PF01061 ABC-2 type transporter 6 207 5.0E-14 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_39770 38496f20c0f7fe4076fd429b06036003 246 PIRSF PIRSF006648 1 244 9.3E-18 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 SUPERFAMILY SSF100950 77 230 2.09E-26 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 SMART SM00420 6 58 1.8E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 Gene3D G3DSA:1.10.10.10 8 51 1.8E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 SUPERFAMILY SSF46785 5 61 3.62E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.0E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.0E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 Pfam PF00455 DeoR C terminal sensor domain 74 229 9.3E-42 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 SMART SM01134 71 231 9.1E-55 T 14-10-2018 A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 3.7E-16 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_07400 02f55276ca2fe506700aa14f9b4fbc23 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_08190 31dfac110d35ccfc0049daf1ed7a5ddc 194 Pfam PF13560 Helix-turn-helix domain 5 60 7.1E-11 T 14-10-2018 A4R43_08190 31dfac110d35ccfc0049daf1ed7a5ddc 194 Gene3D G3DSA:1.10.260.40 4 84 2.0E-15 T 14-10-2018 A4R43_08190 31dfac110d35ccfc0049daf1ed7a5ddc 194 SUPERFAMILY SSF51182 49 178 8.35E-24 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_08190 31dfac110d35ccfc0049daf1ed7a5ddc 194 Gene3D G3DSA:2.60.120.10 93 186 2.5E-16 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_08190 31dfac110d35ccfc0049daf1ed7a5ddc 194 SMART SM00530 9 64 1.6E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_08190 31dfac110d35ccfc0049daf1ed7a5ddc 194 Pfam PF07883 Cupin domain 117 176 1.2E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_08190 31dfac110d35ccfc0049daf1ed7a5ddc 194 SUPERFAMILY SSF47413 2 69 6.76E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 232 254 4.8E-56 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 2 28 4.8E-56 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 254 279 4.8E-56 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 108 135 4.8E-56 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 34 46 4.8E-56 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 86 108 4.8E-56 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 Pfam PF00551 Formyl transferase 86 258 6.0E-37 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 SUPERFAMILY SSF55021 1 76 2.33E-12 T 14-10-2018 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 Gene3D G3DSA:3.40.50.170 84 280 4.2E-70 T 14-10-2018 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 Gene3D G3DSA:3.30.70.260 1 83 4.2E-21 T 14-10-2018 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 4 280 4.9E-99 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 SUPERFAMILY SSF53328 86 280 7.33E-59 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 PIRSF PIRSF036480 1 280 4.8E-109 T 14-10-2018 A4R43_32715 c6b9856fed60cb77a4a3e9a943a1696b 280 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 280 45.85 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 SUPERFAMILY SSF56601 44 296 4.83E-75 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 PRINTS PR00118 Beta-lactamase class A signature 78 95 1.6E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 PRINTS PR00118 Beta-lactamase class A signature 233 248 1.6E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 PRINTS PR00118 Beta-lactamase class A signature 154 178 1.6E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 PRINTS PR00118 Beta-lactamase class A signature 118 143 1.6E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 PRINTS PR00118 Beta-lactamase class A signature 180 205 1.6E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 PRINTS PR00118 Beta-lactamase class A signature 47 71 1.6E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 PRINTS PR00118 Beta-lactamase class A signature 216 231 1.6E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 ProSitePatterns PS00146 Beta-lactamase class-A active site. 80 95 - T 14-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 Pfam PF13354 Beta-lactamase enzyme family 68 273 8.4E-39 T 14-10-2018 A4R43_38770 a68e14fa6e78dd73691a88fdc38e4351 301 Gene3D G3DSA:3.40.710.10 38 300 1.4E-79 T 14-10-2018 A4R43_07755 c261a9d62476daf98bc2b95c3308be2c 194 Pfam PF07336 Putative stress-induced transcription regulator 14 129 3.0E-11 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator A4R43_07755 c261a9d62476daf98bc2b95c3308be2c 194 Pfam PF11706 CGNR zinc finger 144 187 4.0E-16 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_07755 c261a9d62476daf98bc2b95c3308be2c 194 SUPERFAMILY SSF160904 7 186 1.22E-34 T 14-10-2018 A4R43_07755 c261a9d62476daf98bc2b95c3308be2c 194 Gene3D G3DSA:1.10.3300.10 7 189 3.0E-36 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_33615 1bde478855b9113229695d58e664c435 342 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 10 294 4.1E-71 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33615 1bde478855b9113229695d58e664c435 342 Pfam PF02470 MlaD protein 36 112 3.3E-17 T 14-10-2018 IPR003399 Mce/MlaD A4R43_28970 11f48a71c915f6e4226efe04173044fe 766 Gene3D G3DSA:1.10.510.10 94 267 9.4E-39 T 14-10-2018 A4R43_28970 11f48a71c915f6e4226efe04173044fe 766 SUPERFAMILY SSF56112 8 259 2.56E-61 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_28970 11f48a71c915f6e4226efe04173044fe 766 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_28970 11f48a71c915f6e4226efe04173044fe 766 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_28970 11f48a71c915f6e4226efe04173044fe 766 Pfam PF00069 Protein kinase domain 12 251 2.8E-43 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_28970 11f48a71c915f6e4226efe04173044fe 766 Gene3D G3DSA:3.30.200.20 10 93 3.2E-16 T 14-10-2018 A4R43_15920 9fe9e735bc2304f4e7854f75c5537fac 235 Pfam PF08241 Methyltransferase domain 45 138 1.4E-21 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_15920 9fe9e735bc2304f4e7854f75c5537fac 235 Gene3D G3DSA:3.40.50.150 25 232 1.4E-47 T 14-10-2018 A4R43_15920 9fe9e735bc2304f4e7854f75c5537fac 235 SUPERFAMILY SSF53335 9 200 7.0E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_28340 125009f24c84d476f606c08925cf4796 393 SUPERFAMILY SSF51905 3 391 6.04E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_28340 125009f24c84d476f606c08925cf4796 393 Pfam PF01266 FAD dependent oxidoreductase 5 390 3.8E-68 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_06030 8c19a1770862f9bf5355de161352c289 293 Gene3D G3DSA:3.30.465.10 1 167 1.9E-50 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_06030 8c19a1770862f9bf5355de161352c289 293 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 172 279 9.2E-9 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_06030 8c19a1770862f9bf5355de161352c289 293 SMART SM01092 171 281 1.7E-16 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4R43_06030 8c19a1770862f9bf5355de161352c289 293 SUPERFAMILY SSF55447 172 285 5.76E-18 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily A4R43_06030 8c19a1770862f9bf5355de161352c289 293 SUPERFAMILY SSF56176 2 164 2.98E-48 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_06030 8c19a1770862f9bf5355de161352c289 293 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 164 5.0E-45 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4R43_06030 8c19a1770862f9bf5355de161352c289 293 Gene3D G3DSA:3.30.390.50 171 284 1.6E-19 T 14-10-2018 A4R43_20925 5de07599bcca41671062a1f3f71f75c7 330 SUPERFAMILY SSF56601 49 273 9.45E-28 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_20925 5de07599bcca41671062a1f3f71f75c7 330 Pfam PF13354 Beta-lactamase enzyme family 71 267 2.0E-35 T 14-10-2018 A4R43_20925 5de07599bcca41671062a1f3f71f75c7 330 Gene3D G3DSA:3.40.710.10 26 287 2.6E-37 T 14-10-2018 A4R43_18610 4701afd5307f7ed2f4410bf9458de9cf 156 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 55 2.2E-7 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_18610 4701afd5307f7ed2f4410bf9458de9cf 156 SUPERFAMILY SSF47741 85 151 1.7E-31 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_18610 4701afd5307f7ed2f4410bf9458de9cf 156 SUPERFAMILY SSF54292 2 79 2.1E-20 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_18610 4701afd5307f7ed2f4410bf9458de9cf 156 Gene3D G3DSA:1.10.150.120 77 156 1.3E-32 T 14-10-2018 A4R43_18610 4701afd5307f7ed2f4410bf9458de9cf 156 Gene3D G3DSA:3.10.20.30 1 76 5.6E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_18610 4701afd5307f7ed2f4410bf9458de9cf 156 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_18610 4701afd5307f7ed2f4410bf9458de9cf 156 Pfam PF01799 [2Fe-2S] binding domain 74 147 1.6E-30 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_25090 b814331d9a03490851477c8dcf519202 397 SUPERFAMILY SSF47413 4 53 4.22E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_25090 b814331d9a03490851477c8dcf519202 397 Gene3D G3DSA:1.10.260.40 2 74 1.3E-10 T 14-10-2018 A4R43_25090 b814331d9a03490851477c8dcf519202 397 SMART SM00530 8 63 3.0E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_25090 b814331d9a03490851477c8dcf519202 397 Pfam PF13560 Helix-turn-helix domain 5 65 1.1E-12 T 14-10-2018 A4R43_37485 663cf3ad1fda6bc54c64958d5dc17f86 207 SMART SM00421 122 179 5.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37485 663cf3ad1fda6bc54c64958d5dc17f86 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 127 175 1.2E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37485 663cf3ad1fda6bc54c64958d5dc17f86 207 SUPERFAMILY SSF46894 126 185 9.52E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37485 663cf3ad1fda6bc54c64958d5dc17f86 207 Gene3D G3DSA:1.10.10.10 81 188 2.7E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25120 b438120a02f3070b443457af3dc17e46 222 Gene3D G3DSA:1.10.10.60 124 222 5.6E-25 T 14-10-2018 A4R43_25120 b438120a02f3070b443457af3dc17e46 222 Pfam PF12833 Helix-turn-helix domain 141 221 2.0E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_25120 b438120a02f3070b443457af3dc17e46 222 SUPERFAMILY SSF46689 171 221 2.6E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_25120 b438120a02f3070b443457af3dc17e46 222 SMART SM00342 134 219 2.1E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_27435 4bb7bfcc954bf832b37276031422a62a 145 Pfam PF01638 HxlR-like helix-turn-helix 40 126 4.1E-28 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_27435 4bb7bfcc954bf832b37276031422a62a 145 Gene3D G3DSA:1.10.10.10 22 140 4.8E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27435 4bb7bfcc954bf832b37276031422a62a 145 SUPERFAMILY SSF46785 28 137 9.52E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 SUPERFAMILY SSF56731 117 432 2.33E-93 T 14-10-2018 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 SMART SM00766 477 606 7.3E-20 T 14-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Pfam PF01807 CHC2 zinc finger 7 100 2.5E-33 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Gene3D G3DSA:3.90.980.10 111 243 5.7E-35 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 PIRSF PIRSF002811 2 617 1.1E-150 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 SUPERFAMILY SSF57783 4 99 7.48E-32 T 14-10-2018 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Pfam PF13662 Toprim domain 263 333 1.5E-16 T 14-10-2018 IPR006171 TOPRIM domain A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Hamap MF_00974 DNA primase [dnaG]. 4 611 26.249 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Gene3D G3DSA:3.40.1360.10 244 374 3.6E-36 T 14-10-2018 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 SMART SM00400 37 91 1.5E-34 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 TIGRFAM TIGR01391 dnaG: DNA primase 5 423 1.8E-115 T 14-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Pfam PF10410 DnaB-helicase binding domain of primase 376 431 1.7E-15 T 14-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Pfam PF08278 DNA primase DnaG DnaB-binding 478 605 2.3E-25 T 14-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Gene3D G3DSA:3.90.580.10 1 101 2.1E-35 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 SMART SM00493 262 340 5.2E-16 T 14-10-2018 IPR006171 TOPRIM domain A4R43_39840 4461b6db12d009bde5ba16f283d17fd7 628 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 3.5E-35 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal A4R43_05455 09a7fcea6cfcd6508914ed9930f14b73 117 Pfam PF13466 STAS domain 23 103 1.2E-17 T 14-10-2018 IPR002645 STAS domain A4R43_05455 09a7fcea6cfcd6508914ed9930f14b73 117 SUPERFAMILY SSF52091 10 117 1.41E-23 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_05455 09a7fcea6cfcd6508914ed9930f14b73 117 Gene3D G3DSA:3.30.750.24 6 117 2.2E-30 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_05455 09a7fcea6cfcd6508914ed9930f14b73 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 9 112 9.4E-22 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_15965 f30b2497f68c6e006e95ff58bd399afd 348 Pfam PF03060 Nitronate monooxygenase 2 78 2.1E-23 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_15965 f30b2497f68c6e006e95ff58bd399afd 348 Pfam PF03060 Nitronate monooxygenase 79 336 8.4E-70 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4R43_15965 f30b2497f68c6e006e95ff58bd399afd 348 Gene3D G3DSA:3.20.20.70 1 346 3.3E-91 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_15965 f30b2497f68c6e006e95ff58bd399afd 348 SUPERFAMILY SSF51412 2 247 2.9E-56 T 14-10-2018 A4R43_26770 76884b52612ce1e85830f0212cc55ee9 303 Gene3D G3DSA:3.30.1300.10 190 302 3.2E-38 T 14-10-2018 A4R43_26770 76884b52612ce1e85830f0212cc55ee9 303 Pfam PF02569 Pantoate-beta-alanine ligase 19 287 1.4E-91 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4R43_26770 76884b52612ce1e85830f0212cc55ee9 303 Gene3D G3DSA:3.40.50.620 5 189 4.1E-71 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_26770 76884b52612ce1e85830f0212cc55ee9 303 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 22 289 2.1E-80 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4R43_26770 76884b52612ce1e85830f0212cc55ee9 303 Hamap MF_00158 Pantothenate synthetase [panC]. 16 289 37.254 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4R43_26770 76884b52612ce1e85830f0212cc55ee9 303 SUPERFAMILY SSF52374 13 290 1.23E-98 T 14-10-2018 A4R43_08350 fc2a007463956f7d9d68bcafeef3a8a3 66 Gene3D G3DSA:3.90.820.10 1 66 7.3E-30 T 14-10-2018 A4R43_08350 fc2a007463956f7d9d68bcafeef3a8a3 66 Pfam PF03621 MbtH-like protein 3 48 4.5E-21 T 14-10-2018 IPR005153 MbtH-like domain A4R43_08350 fc2a007463956f7d9d68bcafeef3a8a3 66 SMART SM00923 1 49 6.7E-20 T 14-10-2018 IPR005153 MbtH-like domain A4R43_08350 fc2a007463956f7d9d68bcafeef3a8a3 66 SUPERFAMILY SSF160582 3 64 3.79E-27 T 14-10-2018 IPR038020 MbtH-like domain superfamily A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 123 135 - T 14-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 Pfam PF00553 Cellulose binding domain 330 414 3.4E-18 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 Gene3D G3DSA:1.10.510.10 87 260 5.9E-42 T 14-10-2018 A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 SUPERFAMILY SSF49384 327 415 1.26E-19 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 Pfam PF00069 Protein kinase domain 13 252 1.3E-39 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 SUPERFAMILY SSF56112 5 278 2.46E-66 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 Gene3D G3DSA:3.30.200.20 1 86 5.9E-22 T 14-10-2018 A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 Gene3D G3DSA:2.60.40.290 328 423 9.3E-21 T 14-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A4R43_10505 6e0e3d4acbb6be240bed99faa254c126 424 SMART SM00637 330 421 3.9E-21 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.6E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 SUPERFAMILY SSF53850 88 282 2.67E-20 T 14-10-2018 A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 Gene3D G3DSA:3.40.190.10 100 276 1.4E-25 T 14-10-2018 A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 SUPERFAMILY SSF46785 1 83 6.99E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 Gene3D G3DSA:1.10.10.10 1 85 1.9E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 Gene3D G3DSA:3.40.190.10 157 262 1.4E-25 T 14-10-2018 A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 Pfam PF03466 LysR substrate binding domain 88 281 4.8E-19 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_00135 576227ee922c6d7504ab3db4c0374cb9 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-24 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_26530 e72b4aad7fd6efb3abf65c9ae3782b1a 478 Pfam PF00982 Glycosyltransferase family 20 11 472 1.2E-153 T 14-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 A4R43_26530 e72b4aad7fd6efb3abf65c9ae3782b1a 478 Gene3D G3DSA:3.40.50.2000 34 469 2.7E-165 T 14-10-2018 A4R43_26530 e72b4aad7fd6efb3abf65c9ae3782b1a 478 SUPERFAMILY SSF53756 10 472 3.45E-145 T 14-10-2018 A4R43_26530 e72b4aad7fd6efb3abf65c9ae3782b1a 478 Gene3D G3DSA:3.40.50.2000 250 458 2.7E-165 T 14-10-2018 A4R43_00475 0af108fe2b903755d19577db908221ad 334 Gene3D G3DSA:1.10.10.10 252 333 8.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00475 0af108fe2b903755d19577db908221ad 334 SUPERFAMILY SSF46894 269 329 2.24E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_00475 0af108fe2b903755d19577db908221ad 334 Pfam PF00196 Bacterial regulatory proteins, luxR family 278 329 1.2E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00475 0af108fe2b903755d19577db908221ad 334 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 278 292 1.3E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00475 0af108fe2b903755d19577db908221ad 334 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 292 308 1.3E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00475 0af108fe2b903755d19577db908221ad 334 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 308 320 1.3E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_00475 0af108fe2b903755d19577db908221ad 334 SMART SM00421 275 332 4.5E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_09530 5f4e5ce0f5a3a23f17891969928e2089 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 316 4.1E-21 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_09530 5f4e5ce0f5a3a23f17891969928e2089 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 4.1E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_09530 5f4e5ce0f5a3a23f17891969928e2089 326 SUPERFAMILY SSF52540 5 254 1.05E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09530 5f4e5ce0f5a3a23f17891969928e2089 326 Gene3D G3DSA:3.40.50.300 3 325 2.9E-88 T 14-10-2018 A4R43_09530 5f4e5ce0f5a3a23f17891969928e2089 326 SMART SM00382 34 232 8.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_09530 5f4e5ce0f5a3a23f17891969928e2089 326 Pfam PF00005 ABC transporter 25 182 9.2E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_34450 b0d512e7b9c81a4f765f9fb35c9492c7 228 Gene3D G3DSA:2.70.70.10 59 224 7.8E-48 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_34450 b0d512e7b9c81a4f765f9fb35c9492c7 228 Pfam PF01551 Peptidase family M23 122 217 6.1E-34 T 14-10-2018 IPR016047 Peptidase M23 A4R43_34450 b0d512e7b9c81a4f765f9fb35c9492c7 228 SUPERFAMILY SSF51261 97 221 3.66E-51 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_29765 c1e755519ec489d93d6824885b65d6c5 479 Pfam PF00171 Aldehyde dehydrogenase family 15 468 5.3E-157 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_29765 c1e755519ec489d93d6824885b65d6c5 479 Gene3D G3DSA:3.40.309.10 249 438 3.0E-164 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_29765 c1e755519ec489d93d6824885b65d6c5 479 Gene3D G3DSA:3.40.605.10 11 466 3.0E-164 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_29765 c1e755519ec489d93d6824885b65d6c5 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_29765 c1e755519ec489d93d6824885b65d6c5 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_29765 c1e755519ec489d93d6824885b65d6c5 479 SUPERFAMILY SSF53720 6 470 8.64E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_08260 16eb2c06b36c5e7b772e3f93456e4a1c 246 Gene3D G3DSA:3.30.450.40 78 235 2.3E-33 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_08260 16eb2c06b36c5e7b772e3f93456e4a1c 246 Pfam PF01614 Bacterial transcriptional regulator 130 220 4.3E-12 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_08260 16eb2c06b36c5e7b772e3f93456e4a1c 246 SMART SM00346 9 93 3.4E-6 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_08260 16eb2c06b36c5e7b772e3f93456e4a1c 246 Pfam PF09339 IclR helix-turn-helix domain 11 56 1.2E-7 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_08260 16eb2c06b36c5e7b772e3f93456e4a1c 246 SUPERFAMILY SSF46785 11 70 1.05E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08260 16eb2c06b36c5e7b772e3f93456e4a1c 246 Gene3D G3DSA:1.10.10.10 2 73 1.3E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08260 16eb2c06b36c5e7b772e3f93456e4a1c 246 SUPERFAMILY SSF55781 63 239 3.4E-31 T 14-10-2018 A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 SUPERFAMILY SSF46785 15 152 1.81E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 Gene3D G3DSA:1.10.10.10 4 153 1.5E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 SMART SM00347 41 141 9.9E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 131 151 2.3E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 97 2.3E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 81 2.3E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 101 117 2.3E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 Pfam PF01047 MarR family 50 105 5.8E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_31550 0a9f7801b820d1c35454742202ba3597 178 ProSitePatterns PS01117 MarR-type HTH domain signature. 80 114 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_20810 bafcada51cf64c98fd83859c7e636733 481 Gene3D G3DSA:3.40.50.12780 27 340 3.6E-30 T 14-10-2018 A4R43_20810 bafcada51cf64c98fd83859c7e636733 481 SUPERFAMILY SSF56801 53 430 3.01E-10 T 14-10-2018 A4R43_02055 8324f7e76edd7ce33512d8062a054c67 363 SUPERFAMILY SSF53659 3 356 3.65E-112 T 14-10-2018 A4R43_02055 8324f7e76edd7ce33512d8062a054c67 363 SMART SM01329 7 352 2.5E-163 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_02055 8324f7e76edd7ce33512d8062a054c67 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4R43_02055 8324f7e76edd7ce33512d8062a054c67 363 Gene3D G3DSA:3.40.718.10 6 363 3.9E-121 T 14-10-2018 A4R43_02055 8324f7e76edd7ce33512d8062a054c67 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 9 352 3.3E-92 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_15715 e9af1848986d329cde732f92df0fc140 266 SUPERFAMILY SSF53335 20 226 5.52E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_15715 e9af1848986d329cde732f92df0fc140 266 Gene3D G3DSA:3.40.50.150 28 245 4.5E-23 T 14-10-2018 A4R43_15715 e9af1848986d329cde732f92df0fc140 266 Pfam PF13489 Methyltransferase domain 37 170 7.4E-14 T 14-10-2018 A4R43_01480 90f3fda8d2dde4c8b9334c8e6200cbcf 208 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 149 203 4.4E-18 T 14-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type A4R43_01480 90f3fda8d2dde4c8b9334c8e6200cbcf 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 8.7E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01480 90f3fda8d2dde4c8b9334c8e6200cbcf 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 6.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01480 90f3fda8d2dde4c8b9334c8e6200cbcf 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 6.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01480 90f3fda8d2dde4c8b9334c8e6200cbcf 208 SUPERFAMILY SSF46689 10 74 2.41E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01480 90f3fda8d2dde4c8b9334c8e6200cbcf 208 Gene3D G3DSA:1.10.357.10 68 206 3.9E-34 T 14-10-2018 A4R43_01480 90f3fda8d2dde4c8b9334c8e6200cbcf 208 Gene3D G3DSA:1.10.10.60 8 64 1.5E-16 T 14-10-2018 A4R43_01480 90f3fda8d2dde4c8b9334c8e6200cbcf 208 SUPERFAMILY SSF48498 83 198 4.78E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_07055 b7c3bb0ccf7765473d08f5889c432394 640 SUPERFAMILY SSF56436 487 637 1.32E-21 T 14-10-2018 IPR016187 C-type lectin fold A4R43_07055 b7c3bb0ccf7765473d08f5889c432394 640 Gene3D G3DSA:3.90.1580.10 473 619 1.3E-17 T 14-10-2018 A4R43_07055 b7c3bb0ccf7765473d08f5889c432394 640 Pfam PF03781 Sulfatase-modifying factor enzyme 1 477 559 8.5E-16 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A4R43_31295 1b20655499b97d376072e13f15408002 684 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 530 565 9.5E-5 T 14-10-2018 IPR001434 Domain of unknown function DUF11 A4R43_31295 1b20655499b97d376072e13f15408002 684 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 237 264 5.7E-4 T 14-10-2018 IPR001434 Domain of unknown function DUF11 A4R43_31295 1b20655499b97d376072e13f15408002 684 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 40 67 2.8E-5 T 14-10-2018 IPR001434 Domain of unknown function DUF11 A4R43_31295 1b20655499b97d376072e13f15408002 684 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 437 466 7.2E-4 T 14-10-2018 IPR001434 Domain of unknown function DUF11 A4R43_31295 1b20655499b97d376072e13f15408002 684 Pfam PF01345 Domain of unknown function DUF11 30 117 3.4E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 A4R43_31295 1b20655499b97d376072e13f15408002 684 Pfam PF01345 Domain of unknown function DUF11 528 600 1.8E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 A4R43_28795 dac9136ed624d989755372155ed4334a 474 Pfam PF07690 Major Facilitator Superfamily 26 426 7.8E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_28795 dac9136ed624d989755372155ed4334a 474 Gene3D G3DSA:1.20.1250.20 284 474 4.3E-11 T 14-10-2018 A4R43_28795 dac9136ed624d989755372155ed4334a 474 SUPERFAMILY SSF103473 14 467 1.18E-55 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_28795 dac9136ed624d989755372155ed4334a 474 Gene3D G3DSA:1.20.1720.10 22 226 9.2E-43 T 14-10-2018 A4R43_17395 9cce710ec99a4bbc4924447f1923f9ba 295 Pfam PF00069 Protein kinase domain 13 252 1.7E-41 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_17395 9cce710ec99a4bbc4924447f1923f9ba 295 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_17395 9cce710ec99a4bbc4924447f1923f9ba 295 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_17395 9cce710ec99a4bbc4924447f1923f9ba 295 Gene3D G3DSA:1.10.510.10 89 266 1.1E-44 T 14-10-2018 A4R43_17395 9cce710ec99a4bbc4924447f1923f9ba 295 SUPERFAMILY SSF56112 5 261 4.73E-67 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_17395 9cce710ec99a4bbc4924447f1923f9ba 295 Gene3D G3DSA:3.30.200.20 1 87 5.8E-22 T 14-10-2018 A4R43_17395 9cce710ec99a4bbc4924447f1923f9ba 295 SMART SM00220 7 263 6.3E-47 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_41605 2d543a76403f6ece1bb5e5c460a268da 270 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_41605 2d543a76403f6ece1bb5e5c460a268da 270 SUPERFAMILY SSF51717 1 259 1.96E-75 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_41605 2d543a76403f6ece1bb5e5c460a268da 270 Gene3D G3DSA:3.20.20.20 1 270 1.7E-86 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_41605 2d543a76403f6ece1bb5e5c460a268da 270 Pfam PF00809 Pterin binding enzyme 1 241 6.5E-64 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4R43_41605 2d543a76403f6ece1bb5e5c460a268da 270 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 255 6.8E-82 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A4R43_03680 1b383370efbf3a2d016953338c597a83 222 SMART SM00421 144 206 7.8E-4 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03680 1b383370efbf3a2d016953338c597a83 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 188 9.4E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03680 1b383370efbf3a2d016953338c597a83 222 SMART SM00448 6 118 2.7E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_03680 1b383370efbf3a2d016953338c597a83 222 Pfam PF00072 Response regulator receiver domain 9 118 1.0E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_03680 1b383370efbf3a2d016953338c597a83 222 Gene3D G3DSA:3.40.50.2300 3 138 5.5E-13 T 14-10-2018 A4R43_03680 1b383370efbf3a2d016953338c597a83 222 SUPERFAMILY SSF46894 139 195 1.19E-10 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_03680 1b383370efbf3a2d016953338c597a83 222 Gene3D G3DSA:1.10.10.10 139 211 2.6E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03680 1b383370efbf3a2d016953338c597a83 222 SUPERFAMILY SSF52172 7 130 1.2E-15 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_19585 90ba5c6570dc00d24eb0b24d03c45e1d 215 Pfam PF00216 Bacterial DNA-binding protein 3 89 1.9E-24 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4R43_19585 90ba5c6570dc00d24eb0b24d03c45e1d 215 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 9.2E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4R43_19585 90ba5c6570dc00d24eb0b24d03c45e1d 215 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 9.2E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4R43_19585 90ba5c6570dc00d24eb0b24d03c45e1d 215 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 9.2E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4R43_19585 90ba5c6570dc00d24eb0b24d03c45e1d 215 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4R43_19585 90ba5c6570dc00d24eb0b24d03c45e1d 215 SUPERFAMILY SSF47729 3 93 2.06E-24 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4R43_19585 90ba5c6570dc00d24eb0b24d03c45e1d 215 Gene3D G3DSA:4.10.520.10 2 99 9.6E-30 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4R43_19585 90ba5c6570dc00d24eb0b24d03c45e1d 215 SMART SM00411 2 90 1.4E-32 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4R43_39250 d09d134d7249931ce4f1a8ba4848e0b4 1039 SUPERFAMILY SSF50249 418 501 3.14E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_39250 d09d134d7249931ce4f1a8ba4848e0b4 1039 Pfam PF10150 Ribonuclease E/G family 497 771 1.6E-104 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A4R43_39250 d09d134d7249931ce4f1a8ba4848e0b4 1039 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 32 82 1.3E-8 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal A4R43_39250 d09d134d7249931ce4f1a8ba4848e0b4 1039 Gene3D G3DSA:2.40.50.140 411 501 8.8E-28 T 14-10-2018 A4R43_39250 d09d134d7249931ce4f1a8ba4848e0b4 1039 SMART SM00316 416 495 5.3E-7 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_39250 d09d134d7249931ce4f1a8ba4848e0b4 1039 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 393 796 7.0E-151 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 A4R43_39250 d09d134d7249931ce4f1a8ba4848e0b4 1039 Gene3D G3DSA:1.10.10.2480 32 96 3.5E-8 T 14-10-2018 A4R43_08830 1090372b9213b8ee39e20de992f06eeb 256 SUPERFAMILY SSF53474 4 237 1.01E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08830 1090372b9213b8ee39e20de992f06eeb 256 Pfam PF12697 Alpha/beta hydrolase family 23 229 2.0E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_08830 1090372b9213b8ee39e20de992f06eeb 256 Gene3D G3DSA:3.40.50.1820 2 240 8.6E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_31160 387a2e23b972302a4166571e0249b025 484 Pfam PF01546 Peptidase family M20/M25/M40 107 479 2.8E-24 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_31160 387a2e23b972302a4166571e0249b025 484 Gene3D G3DSA:3.40.630.10 392 478 2.3E-43 T 14-10-2018 A4R43_31160 387a2e23b972302a4166571e0249b025 484 Gene3D G3DSA:3.40.630.10 18 220 6.3E-97 T 14-10-2018 A4R43_31160 387a2e23b972302a4166571e0249b025 484 Pfam PF07687 Peptidase dimerisation domain 219 376 2.0E-10 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_31160 387a2e23b972302a4166571e0249b025 484 Gene3D G3DSA:3.30.70.360 221 279 6.3E-97 T 14-10-2018 A4R43_31160 387a2e23b972302a4166571e0249b025 484 Gene3D G3DSA:3.30.70.360 321 391 2.3E-43 T 14-10-2018 A4R43_31160 387a2e23b972302a4166571e0249b025 484 SUPERFAMILY SSF53187 25 480 9.43E-46 T 14-10-2018 A4R43_02840 c758a030615b7908b89592231923940f 61 Gene3D G3DSA:1.10.10.10 1 59 2.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02840 c758a030615b7908b89592231923940f 61 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 8 24 3.6E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_02840 c758a030615b7908b89592231923940f 61 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 24 36 3.6E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_02840 c758a030615b7908b89592231923940f 61 SUPERFAMILY SSF46894 1 54 5.44E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_02840 c758a030615b7908b89592231923940f 61 Pfam PF00196 Bacterial regulatory proteins, luxR family 1 47 9.7E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_02840 c758a030615b7908b89592231923940f 61 SMART SM00421 1 48 9.6E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_40760 acc918b916f86275106d684916f51de0 481 SUPERFAMILY SSF89796 10 207 3.79E-18 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_40760 acc918b916f86275106d684916f51de0 481 Gene3D G3DSA:3.40.50.10540 221 445 3.4E-54 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_40760 acc918b916f86275106d684916f51de0 481 Gene3D G3DSA:3.40.50.10540 10 196 1.9E-12 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_40760 acc918b916f86275106d684916f51de0 481 Pfam PF02515 CoA-transferase family III 226 428 2.2E-46 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_40760 acc918b916f86275106d684916f51de0 481 Pfam PF02515 CoA-transferase family III 19 196 2.9E-11 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_40760 acc918b916f86275106d684916f51de0 481 Gene3D G3DSA:3.30.1540.10 109 195 1.9E-12 T 14-10-2018 A4R43_40760 acc918b916f86275106d684916f51de0 481 SUPERFAMILY SSF89796 224 468 7.72E-52 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_37660 7db633871699d0d635060ab21aa8e027 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 445 1.0E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_37660 7db633871699d0d635060ab21aa8e027 446 SMART SM00388 233 298 8.4E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 SUPERFAMILY SSF47384 216 296 2.35E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 Gene3D G3DSA:3.30.565.10 306 446 7.4E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_37660 7db633871699d0d635060ab21aa8e027 446 SMART SM00304 179 232 8.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 297 1.5E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 Pfam PF00672 HAMP domain 180 227 1.9E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 444 3.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 3.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 3.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 399 3.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 SUPERFAMILY SSF158472 181 228 3.27E-8 T 14-10-2018 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 Gene3D G3DSA:1.20.1480.50 140 232 7.8E-12 T 14-10-2018 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 Gene3D G3DSA:1.10.287.130 233 298 8.2E-15 T 14-10-2018 A4R43_37660 7db633871699d0d635060ab21aa8e027 446 SUPERFAMILY SSF55874 288 445 1.96E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_37660 7db633871699d0d635060ab21aa8e027 446 SMART SM00387 336 446 1.2E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_03850 f97adb7213a16028df059684b911edfc 309 SUPERFAMILY SSF51735 112 279 7.28E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_03850 f97adb7213a16028df059684b911edfc 309 Gene3D G3DSA:3.90.180.10 11 304 5.1E-54 T 14-10-2018 A4R43_03850 f97adb7213a16028df059684b911edfc 309 Pfam PF13602 Zinc-binding dehydrogenase 178 305 3.5E-15 T 14-10-2018 A4R43_03850 f97adb7213a16028df059684b911edfc 309 SUPERFAMILY SSF50129 9 141 1.19E-20 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_03850 f97adb7213a16028df059684b911edfc 309 Gene3D G3DSA:3.40.50.720 118 255 5.1E-54 T 14-10-2018 A4R43_03850 f97adb7213a16028df059684b911edfc 309 SMART SM00829 9 305 2.0E-9 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_23250 44dfc91d1bd85e6dbe51088e1c00433a 784 SUPERFAMILY SSF53474 560 633 5.26E-7 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_23250 44dfc91d1bd85e6dbe51088e1c00433a 784 Pfam PF01764 Lipase (class 3) 572 620 9.3E-5 T 14-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 A4R43_16605 d93f4c122f0a8ce9c9c2f85397ce953b 414 Pfam PF02470 MlaD protein 40 115 4.1E-15 T 14-10-2018 IPR003399 Mce/MlaD A4R43_16605 d93f4c122f0a8ce9c9c2f85397ce953b 414 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 294 5.0E-57 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 SUPERFAMILY SSF51735 3 246 5.63E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 9.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 9.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 Gene3D G3DSA:3.40.50.720 1 291 2.3E-79 T 14-10-2018 A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.8E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.8E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 8.8E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.8E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 8.8E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 215 4.8E-4 T 14-10-2018 A4R43_16650 f809812a8633b0f6238e34773b21dde3 292 Pfam PF00106 short chain dehydrogenase 7 198 2.5E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05160 33fbaa2db85843726a7afdcefc209c96 152 Pfam PF00578 AhpC/TSA family 4 125 1.7E-31 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_05160 33fbaa2db85843726a7afdcefc209c96 152 PIRSF PIRSF000239 1 152 5.7E-20 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_05160 33fbaa2db85843726a7afdcefc209c96 152 Gene3D G3DSA:3.40.30.10 1 151 4.3E-42 T 14-10-2018 A4R43_05160 33fbaa2db85843726a7afdcefc209c96 152 SUPERFAMILY SSF52833 3 148 9.68E-42 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_08555 05c2a6a164e27e3525d43453459a916d 320 Pfam PF12679 ABC-2 family transporter protein 45 186 2.7E-6 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 Pfam PF00067 Cytochrome P450 240 338 2.1E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 SUPERFAMILY SSF48264 14 361 2.23E-45 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 310 319 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 Gene3D G3DSA:1.10.630.10 4 365 7.4E-64 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00359 B-class P450 signature 317 328 3.7E-13 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00359 B-class P450 signature 70 81 3.7E-13 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00359 B-class P450 signature 241 252 3.7E-13 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00359 B-class P450 signature 133 148 3.7E-13 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00359 B-class P450 signature 308 317 3.7E-13 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00359 B-class P450 signature 116 132 3.7E-13 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00385 P450 superfamily signature 317 328 1.6E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00385 P450 superfamily signature 209 226 1.6E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00385 P450 superfamily signature 308 317 1.6E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_08295 700d147b98b3e9987c2b733c2e45da70 365 PRINTS PR00385 P450 superfamily signature 241 252 1.6E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06205 294d3996b0f9d3068ab852f783b814fb 402 SUPERFAMILY SSF103473 7 388 3.01E-68 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_06205 294d3996b0f9d3068ab852f783b814fb 402 Pfam PF07690 Major Facilitator Superfamily 18 296 3.4E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_06205 294d3996b0f9d3068ab852f783b814fb 402 Gene3D G3DSA:1.20.1250.20 11 392 4.5E-64 T 14-10-2018 A4R43_37760 ea7f5910b7169a183bd17411136b1b3a 304 Gene3D G3DSA:1.10.287.100 225 267 2.9E-16 T 14-10-2018 A4R43_37760 ea7f5910b7169a183bd17411136b1b3a 304 Pfam PF09754 PAC2 family 27 243 5.6E-44 T 14-10-2018 IPR019151 Proteasome assembly chaperone 2 A4R43_37760 ea7f5910b7169a183bd17411136b1b3a 304 SUPERFAMILY SSF159659 5 267 1.7E-87 T 14-10-2018 A4R43_37760 ea7f5910b7169a183bd17411136b1b3a 304 Gene3D G3DSA:3.40.50.10900 2 223 3.7E-72 T 14-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A4R43_37760 ea7f5910b7169a183bd17411136b1b3a 304 PIRSF PIRSF028754 6 304 4.2E-97 T 14-10-2018 IPR008492 Protein of unknown function DUF774 A4R43_22690 4abd328c6e1df2b44bff8686fcb50efd 314 Gene3D G3DSA:3.40.50.720 126 296 2.7E-87 T 14-10-2018 A4R43_22690 4abd328c6e1df2b44bff8686fcb50efd 314 SUPERFAMILY SSF51735 3 311 4.83E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22690 4abd328c6e1df2b44bff8686fcb50efd 314 PIRSF PIRSF001439 1 312 1.5E-71 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A4R43_22690 4abd328c6e1df2b44bff8686fcb50efd 314 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 9 311 1.7E-59 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A4R43_22690 4abd328c6e1df2b44bff8686fcb50efd 314 Gene3D G3DSA:3.30.1780.10 9 311 2.7E-87 T 14-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 A4R43_36815 dec403e48e03ef409f224bca34773a48 193 SUPERFAMILY SSF48498 82 185 2.58E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_36815 dec403e48e03ef409f224bca34773a48 193 Gene3D G3DSA:1.10.10.60 2 56 3.1E-13 T 14-10-2018 A4R43_36815 dec403e48e03ef409f224bca34773a48 193 Gene3D G3DSA:1.10.357.10 57 186 7.5E-19 T 14-10-2018 A4R43_36815 dec403e48e03ef409f224bca34773a48 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 60 2.3E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36815 dec403e48e03ef409f224bca34773a48 193 SUPERFAMILY SSF46689 6 83 1.13E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_05315 67d9314f50ec87685a865aa9940c5dc4 209 SUPERFAMILY SSF46689 24 99 6.16E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_05315 67d9314f50ec87685a865aa9940c5dc4 209 SUPERFAMILY SSF48498 96 207 3.26E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_05315 67d9314f50ec87685a865aa9940c5dc4 209 Gene3D G3DSA:1.10.10.60 24 67 1.6E-20 T 14-10-2018 A4R43_05315 67d9314f50ec87685a865aa9940c5dc4 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 3.0E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05315 67d9314f50ec87685a865aa9940c5dc4 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 3.0E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05315 67d9314f50ec87685a865aa9940c5dc4 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 8.9E-20 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05315 67d9314f50ec87685a865aa9940c5dc4 209 Gene3D G3DSA:1.10.357.10 68 208 9.8E-34 T 14-10-2018 A4R43_05315 67d9314f50ec87685a865aa9940c5dc4 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_03090 11120e3c0d5d5247c44ba90b5578a2bb 274 Pfam PF12833 Helix-turn-helix domain 186 260 9.2E-12 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03090 11120e3c0d5d5247c44ba90b5578a2bb 274 Gene3D G3DSA:1.10.10.60 160 265 2.4E-14 T 14-10-2018 A4R43_03090 11120e3c0d5d5247c44ba90b5578a2bb 274 SMART SM00342 180 262 2.9E-4 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_40290 b9e90ad18ae77f4006ab2f624a785614 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 303 2.7E-14 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_40290 b9e90ad18ae77f4006ab2f624a785614 340 Pfam PF01548 Transposase 4 154 5.5E-26 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_05000 b9e90ad18ae77f4006ab2f624a785614 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 303 2.7E-14 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_05000 b9e90ad18ae77f4006ab2f624a785614 340 Pfam PF01548 Transposase 4 154 5.5E-26 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 61 583 50.322 T 14-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 281 434 5.8E-48 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 Gene3D G3DSA:1.10.8.60 435 456 3.1E-60 T 14-10-2018 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 Pfam PF16450 Proteasomal ATPase OB/ID domain 103 238 7.0E-53 T 14-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 59 582 8.2E-255 T 14-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 Gene3D G3DSA:2.40.50.140 100 159 2.4E-28 T 14-10-2018 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 Gene3D G3DSA:3.40.50.300 240 434 3.1E-60 T 14-10-2018 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 Gene3D G3DSA:1.20.5.170 58 99 5.6E-16 T 14-10-2018 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 SUPERFAMILY SSF52540 239 546 2.23E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 ProSitePatterns PS00674 AAA-protein family signature. 404 422 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 SMART SM00382 277 436 4.2E-22 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10815 7c61134370ce0da1fff9cb5ba02662fd 604 Gene3D G3DSA:2.40.50.140 160 239 9.1E-25 T 14-10-2018 A4R43_38755 eacf1be0824f943fe671efd130547cc6 126 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38755 eacf1be0824f943fe671efd130547cc6 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38755 eacf1be0824f943fe671efd130547cc6 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38755 eacf1be0824f943fe671efd130547cc6 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38755 eacf1be0824f943fe671efd130547cc6 126 Gene3D G3DSA:1.10.1660.10 1 121 1.9E-29 T 14-10-2018 A4R43_38755 eacf1be0824f943fe671efd130547cc6 126 SUPERFAMILY SSF46955 1 111 1.03E-26 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_38755 eacf1be0824f943fe671efd130547cc6 126 Pfam PF13411 MerR HTH family regulatory protein 1 66 5.2E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_38755 eacf1be0824f943fe671efd130547cc6 126 SMART SM00422 1 69 6.6E-19 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_05460 4446e3274d07920d7dcdc43fef545619 121 Pfam PF01740 STAS domain 13 113 4.6E-12 T 14-10-2018 IPR002645 STAS domain A4R43_05460 4446e3274d07920d7dcdc43fef545619 121 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 6 111 2.9E-19 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_05460 4446e3274d07920d7dcdc43fef545619 121 Gene3D G3DSA:3.30.750.24 3 119 3.1E-24 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_05460 4446e3274d07920d7dcdc43fef545619 121 SUPERFAMILY SSF52091 7 115 6.47E-17 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_04560 108ca62f52b12afcdaf9301749cff542 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 308 8.9E-13 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_04560 108ca62f52b12afcdaf9301749cff542 314 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_04560 108ca62f52b12afcdaf9301749cff542 314 SUPERFAMILY SSF51735 104 282 1.75E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04560 108ca62f52b12afcdaf9301749cff542 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 282 3.6E-57 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_04560 108ca62f52b12afcdaf9301749cff542 314 Gene3D G3DSA:3.40.50.720 2 306 1.8E-126 T 14-10-2018 A4R43_04560 108ca62f52b12afcdaf9301749cff542 314 SUPERFAMILY SSF52283 1 121 4.68E-25 T 14-10-2018 A4R43_04560 108ca62f52b12afcdaf9301749cff542 314 Gene3D G3DSA:3.40.50.720 103 298 1.8E-126 T 14-10-2018 A4R43_22210 907718887c196744fbf892da8b736b2e 237 Gene3D G3DSA:2.60.120.10 1 78 1.6E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_22210 907718887c196744fbf892da8b736b2e 237 SMART SM00342 154 236 3.8E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_22210 907718887c196744fbf892da8b736b2e 237 Pfam PF02311 AraC-like ligand binding domain 16 66 2.1E-4 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4R43_22210 907718887c196744fbf892da8b736b2e 237 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 220 236 7.5E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_22210 907718887c196744fbf892da8b736b2e 237 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 205 220 7.5E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_22210 907718887c196744fbf892da8b736b2e 237 Pfam PF12833 Helix-turn-helix domain 162 235 4.5E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_22210 907718887c196744fbf892da8b736b2e 237 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 191 232 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_22210 907718887c196744fbf892da8b736b2e 237 SUPERFAMILY SSF46689 190 235 1.7E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22210 907718887c196744fbf892da8b736b2e 237 Gene3D G3DSA:1.10.10.60 139 237 1.5E-20 T 14-10-2018 A4R43_22210 907718887c196744fbf892da8b736b2e 237 SUPERFAMILY SSF51182 3 159 3.11E-15 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_01345 eaa30d8dc0c4895874e7a73547c9b24c 158 Pfam PF01799 [2Fe-2S] binding domain 75 151 7.4E-24 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_01345 eaa30d8dc0c4895874e7a73547c9b24c 158 Gene3D G3DSA:3.10.20.30 2 76 1.5E-19 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_01345 eaa30d8dc0c4895874e7a73547c9b24c 158 SUPERFAMILY SSF54292 4 90 1.17E-20 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_01345 eaa30d8dc0c4895874e7a73547c9b24c 158 SUPERFAMILY SSF47741 88 156 1.31E-25 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_01345 eaa30d8dc0c4895874e7a73547c9b24c 158 Gene3D G3DSA:1.10.150.120 77 158 2.8E-24 T 14-10-2018 A4R43_01345 eaa30d8dc0c4895874e7a73547c9b24c 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 57 4.8E-6 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_27890 7b151065d80ac2f7d315684d4d5e6689 272 SUPERFAMILY SSF53335 11 222 6.01E-55 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_27890 7b151065d80ac2f7d315684d4d5e6689 272 PIRSF PIRSF028177 1 272 2.2E-70 T 14-10-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 A4R43_27890 7b151065d80ac2f7d315684d4d5e6689 272 Gene3D G3DSA:3.40.50.150 5 269 9.9E-46 T 14-10-2018 A4R43_27890 7b151065d80ac2f7d315684d4d5e6689 272 Pfam PF04072 Leucine carboxyl methyltransferase 20 174 1.8E-20 T 14-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 A4R43_39330 1dbe401e2e90d7f4cd072b96c6d2030a 201 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 A4R43_39330 1dbe401e2e90d7f4cd072b96c6d2030a 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 196 9.2E-56 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_39330 1dbe401e2e90d7f4cd072b96c6d2030a 201 SUPERFAMILY SSF53254 3 196 3.8E-58 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_39330 1dbe401e2e90d7f4cd072b96c6d2030a 201 PIRSF PIRSF000709 1 174 5.7E-14 T 14-10-2018 A4R43_39330 1dbe401e2e90d7f4cd072b96c6d2030a 201 Gene3D G3DSA:3.40.50.1240 2 200 4.4E-69 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_39330 1dbe401e2e90d7f4cd072b96c6d2030a 201 SMART SM00855 4 157 1.1E-16 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_17625 01f4f8c22058839018db8ff6ffc2f3d2 208 Gene3D G3DSA:3.40.50.300 15 196 2.9E-13 T 14-10-2018 A4R43_17625 01f4f8c22058839018db8ff6ffc2f3d2 208 SUPERFAMILY SSF52540 41 163 8.27E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04190 79363353eb9532555309e8162ab229c4 380 Pfam PF13692 Glycosyl transferases group 1 190 330 1.7E-26 T 14-10-2018 A4R43_04190 79363353eb9532555309e8162ab229c4 380 Pfam PF13439 Glycosyltransferase Family 4 14 173 2.4E-26 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_04190 79363353eb9532555309e8162ab229c4 380 Gene3D G3DSA:3.40.50.2000 171 348 1.5E-116 T 14-10-2018 A4R43_04190 79363353eb9532555309e8162ab229c4 380 SUPERFAMILY SSF53756 4 365 4.97E-73 T 14-10-2018 A4R43_04190 79363353eb9532555309e8162ab229c4 380 Gene3D G3DSA:3.40.50.2000 11 361 1.5E-116 T 14-10-2018 A4R43_31475 5f3d8af4b9357a9312298be9d60258f2 261 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 85 4.0E-16 T 14-10-2018 IPR027805 Transposase, Helix-turn-helix domain A4R43_31475 5f3d8af4b9357a9312298be9d60258f2 261 Pfam PF13359 DDE superfamily endonuclease 104 255 5.6E-27 T 14-10-2018 IPR027806 Harbinger transposase-derived nuclease domain A4R43_35780 5f3d8af4b9357a9312298be9d60258f2 261 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 85 4.0E-16 T 14-10-2018 IPR027805 Transposase, Helix-turn-helix domain A4R43_35780 5f3d8af4b9357a9312298be9d60258f2 261 Pfam PF13359 DDE superfamily endonuclease 104 255 5.6E-27 T 14-10-2018 IPR027806 Harbinger transposase-derived nuclease domain A4R43_20865 d6e9e3c9da937679a29451a9ba1a133e 105 Pfam PF03551 Transcriptional regulator PadR-like family 31 79 5.4E-12 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_20865 d6e9e3c9da937679a29451a9ba1a133e 105 SUPERFAMILY SSF46785 7 94 3.99E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20865 d6e9e3c9da937679a29451a9ba1a133e 105 Gene3D G3DSA:1.10.10.10 3 98 4.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 249 392 8.4E-32 T 14-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 70 245 1.4E-64 T 14-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 SUPERFAMILY SSF55545 7 69 1.7E-13 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 5 66 5.1E-10 T 14-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 PRINTS PR00738 Glycosyl hydrolase family 20 signature 232 245 1.3E-42 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 PRINTS PR00738 Glycosyl hydrolase family 20 signature 374 391 1.3E-42 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 PRINTS PR00738 Glycosyl hydrolase family 20 signature 23 43 1.3E-42 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 PRINTS PR00738 Glycosyl hydrolase family 20 signature 64 81 1.3E-42 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 PRINTS PR00738 Glycosyl hydrolase family 20 signature 93 114 1.3E-42 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 PRINTS PR00738 Glycosyl hydrolase family 20 signature 164 181 1.3E-42 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 PRINTS PR00738 Glycosyl hydrolase family 20 signature 356 372 1.3E-42 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 SUPERFAMILY SSF51445 70 404 5.62E-104 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 Gene3D G3DSA:3.20.20.80 69 392 1.7E-119 T 14-10-2018 A4R43_14445 f1d6df801d131a2939d9f7907f61089b 439 Gene3D G3DSA:3.30.379.10 1 68 4.8E-13 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4R43_00025 b9a73481b1a180da4c531bb6fdb3f928 334 SUPERFAMILY SSF56601 14 313 4.28E-57 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_00025 b9a73481b1a180da4c531bb6fdb3f928 334 Pfam PF00144 Beta-lactamase 23 317 9.9E-56 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_00025 b9a73481b1a180da4c531bb6fdb3f928 334 Gene3D G3DSA:3.40.710.30 2 330 4.7E-105 T 14-10-2018 A4R43_34695 223163bd299f0e5ad2949c34883abd25 744 SMART SM00089 460 546 7.6E-13 T 14-10-2018 IPR022409 PKD/Chitinase domain A4R43_34695 223163bd299f0e5ad2949c34883abd25 744 Pfam PF00801 PKD domain 464 535 2.8E-5 T 14-10-2018 IPR000601 PKD domain A4R43_34695 223163bd299f0e5ad2949c34883abd25 744 Gene3D G3DSA:2.60.40.10 452 545 1.8E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_34695 223163bd299f0e5ad2949c34883abd25 744 SUPERFAMILY SSF49299 456 547 2.62E-17 T 14-10-2018 IPR035986 PKD domain superfamily A4R43_34695 223163bd299f0e5ad2949c34883abd25 744 Pfam PF07995 Glucose / Sorbosone dehydrogenase 228 410 1.8E-15 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_34695 223163bd299f0e5ad2949c34883abd25 744 Pfam PF07995 Glucose / Sorbosone dehydrogenase 34 188 1.4E-12 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_34695 223163bd299f0e5ad2949c34883abd25 744 Gene3D G3DSA:2.120.10.30 13 417 2.8E-68 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_34695 223163bd299f0e5ad2949c34883abd25 744 SUPERFAMILY SSF50952 19 411 1.06E-20 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_20345 6d0d27c360ac97bef5d06e78b8968cfc 291 Pfam PF12697 Alpha/beta hydrolase family 55 268 1.6E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_20345 6d0d27c360ac97bef5d06e78b8968cfc 291 SUPERFAMILY SSF53474 28 284 4.85E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20345 6d0d27c360ac97bef5d06e78b8968cfc 291 Gene3D G3DSA:3.40.50.1820 6 286 6.7E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 80 20.258 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 77 1.0E-21 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 Pfam PF01084 Ribosomal protein S18 26 75 4.2E-23 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 79 2.6E-27 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 SUPERFAMILY SSF46911 6 79 8.63E-25 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 7.0E-16 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 7.0E-16 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 7.0E-16 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 7.0E-16 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 Gene3D G3DSA:4.10.640.10 2 82 1.1E-27 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30760 17e603bbd2f06cd838e88130a50ef403 82 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 14-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 SUPERFAMILY SSF46785 4 88 6.2E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 65 1.9E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 Pfam PF03466 LysR substrate binding domain 91 288 4.8E-31 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 SUPERFAMILY SSF53850 93 292 2.33E-28 T 14-10-2018 A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 Gene3D G3DSA:3.40.190.10 165 267 1.8E-31 T 14-10-2018 A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 Gene3D G3DSA:3.40.190.10 94 286 1.8E-31 T 14-10-2018 A4R43_06810 d3495307bc926618d1a4b10d059ce902 293 Gene3D G3DSA:1.10.10.10 1 87 1.1E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09370 a676072541faa741a257b7c623d158d4 332 SUPERFAMILY SSF81345 2 322 2.35E-64 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_09370 a676072541faa741a257b7c623d158d4 332 Gene3D G3DSA:1.10.3470.10 2 328 4.4E-74 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_09370 a676072541faa741a257b7c623d158d4 332 Pfam PF01032 FecCD transport family 14 319 9.1E-70 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 160 260 1.9E-20 T 14-10-2018 A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 2.8E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 2.8E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.8E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.8E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 2.8E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 SUPERFAMILY SSF51735 4 264 1.75E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 Gene3D G3DSA:3.40.50.720 2 267 2.3E-45 T 14-10-2018 A4R43_09810 9399e4aaa21f813fce41bfa52a0a2763 270 Pfam PF00106 short chain dehydrogenase 4 133 4.7E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_01765 14730c84e7f75afebc9021e55978d8cb 141 SUPERFAMILY SSF46955 6 106 1.5E-25 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_01765 14730c84e7f75afebc9021e55978d8cb 141 Gene3D G3DSA:1.10.1660.10 1 122 4.9E-27 T 14-10-2018 A4R43_01765 14730c84e7f75afebc9021e55978d8cb 141 SMART SM00422 6 74 6.4E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_01765 14730c84e7f75afebc9021e55978d8cb 141 Pfam PF13411 MerR HTH family regulatory protein 7 72 8.5E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_01765 14730c84e7f75afebc9021e55978d8cb 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 6.0E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_01765 14730c84e7f75afebc9021e55978d8cb 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 6.0E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_01765 14730c84e7f75afebc9021e55978d8cb 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 6.0E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_02650 44ed1fc02d41c2117a5ea6b30014a024 208 Pfam PF01799 [2Fe-2S] binding domain 127 199 9.5E-28 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_02650 44ed1fc02d41c2117a5ea6b30014a024 208 Gene3D G3DSA:1.10.150.120 129 208 3.5E-30 T 14-10-2018 A4R43_02650 44ed1fc02d41c2117a5ea6b30014a024 208 Gene3D G3DSA:3.10.20.30 46 128 6.2E-31 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_02650 44ed1fc02d41c2117a5ea6b30014a024 208 SUPERFAMILY SSF54292 49 141 8.0E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_02650 44ed1fc02d41c2117a5ea6b30014a024 208 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 93 101 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_02650 44ed1fc02d41c2117a5ea6b30014a024 208 SUPERFAMILY SSF47741 138 206 7.2E-29 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_02650 44ed1fc02d41c2117a5ea6b30014a024 208 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 61 115 7.8E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_40200 01f737edcd4e595b34b37f94cb225da7 65 Gene3D G3DSA:3.30.70.20 1 64 2.9E-20 T 14-10-2018 A4R43_40200 01f737edcd4e595b34b37f94cb225da7 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.4E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_40200 01f737edcd4e595b34b37f94cb225da7 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 3.4E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_40200 01f737edcd4e595b34b37f94cb225da7 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.4E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4R43_40200 01f737edcd4e595b34b37f94cb225da7 65 SUPERFAMILY SSF54862 2 62 5.39E-15 T 14-10-2018 A4R43_40200 01f737edcd4e595b34b37f94cb225da7 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 2.0E-13 T 14-10-2018 A4R43_15310 9ffbd814da8092b4c8047f3a2dd3dab8 225 Gene3D G3DSA:3.30.300.130 1 96 5.8E-17 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4R43_15310 9ffbd814da8092b4c8047f3a2dd3dab8 225 Pfam PF01883 Iron-sulfur cluster assembly protein 4 74 4.3E-17 T 14-10-2018 IPR002744 MIP18 family-like A4R43_15310 9ffbd814da8092b4c8047f3a2dd3dab8 225 SUPERFAMILY SSF117916 2 83 7.19E-16 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4R43_14405 7b438c9ea043fbc9a5ebc3c6b6e62804 433 Gene3D G3DSA:2.40.37.20 43 433 2.6E-132 T 14-10-2018 A4R43_14405 7b438c9ea043fbc9a5ebc3c6b6e62804 433 Gene3D G3DSA:3.20.20.10 60 299 2.6E-132 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_14405 7b438c9ea043fbc9a5ebc3c6b6e62804 433 SMART SM01119 322 419 1.4E-28 T 14-10-2018 IPR026956 D-serine dehydratase-like domain A4R43_14405 7b438c9ea043fbc9a5ebc3c6b6e62804 433 Pfam PF14031 Putative serine dehydratase domain 322 418 1.8E-12 T 14-10-2018 IPR026956 D-serine dehydratase-like domain A4R43_14405 7b438c9ea043fbc9a5ebc3c6b6e62804 433 SUPERFAMILY SSF51419 60 274 3.27E-24 T 14-10-2018 IPR029066 PLP-binding barrel A4R43_14405 7b438c9ea043fbc9a5ebc3c6b6e62804 433 Pfam PF01168 Alanine racemase, N-terminal domain 59 240 1.4E-12 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4R43_28475 d886a47640bc02ca1c17243772f23b8f 214 Pfam PF14219 Domain of unknown function (DUF4328) 53 210 9.9E-42 T 14-10-2018 IPR025565 Domain of unknown function DUF4328 A4R43_10635 637e84621ef700d589bc74d0115ccfc0 463 Pfam PF00083 Sugar (and other) transporter 52 450 5.2E-48 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_10635 637e84621ef700d589bc74d0115ccfc0 463 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_10635 637e84621ef700d589bc74d0115ccfc0 463 SUPERFAMILY SSF103473 7 448 1.57E-88 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_10635 637e84621ef700d589bc74d0115ccfc0 463 Gene3D G3DSA:1.20.1250.20 13 451 2.7E-91 T 14-10-2018 A4R43_13450 6ae5513a02388da1c6fef5a89feb28b6 308 Gene3D G3DSA:3.40.50.1820 1 301 2.9E-83 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13450 6ae5513a02388da1c6fef5a89feb28b6 308 SUPERFAMILY SSF53474 19 305 2.89E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13450 6ae5513a02388da1c6fef5a89feb28b6 308 Pfam PF07859 alpha/beta hydrolase fold 76 281 1.1E-67 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_12295 38096fd69cd905162dc0bf6045db3dba 459 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 8 456 1.9E-55 T 14-10-2018 IPR006707 Type VII secretion system membrane protein EccD A4R43_12295 38096fd69cd905162dc0bf6045db3dba 459 PIRSF PIRSF017804 1 459 8.4E-79 T 14-10-2018 IPR006707 Type VII secretion system membrane protein EccD A4R43_12295 38096fd69cd905162dc0bf6045db3dba 459 Gene3D G3DSA:3.10.20.90 2 83 9.3E-8 T 14-10-2018 A4R43_12295 38096fd69cd905162dc0bf6045db3dba 459 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 5 81 4.0E-19 T 14-10-2018 IPR024962 YukD-like A4R43_39615 9bf517c4f94f83b38c34a7ea26e28bb3 124 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 48 65 - T 14-10-2018 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 A4R43_39615 9bf517c4f94f83b38c34a7ea26e28bb3 124 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 45 112 2.0E-11 T 14-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 A4R43_39615 9bf517c4f94f83b38c34a7ea26e28bb3 124 Gene3D G3DSA:3.30.350.10 26 124 1.6E-30 T 14-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 A4R43_39615 9bf517c4f94f83b38c34a7ea26e28bb3 124 SUPERFAMILY SSF55399 41 123 4.32E-24 T 14-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 A4R43_39615 9bf517c4f94f83b38c34a7ea26e28bb3 124 Pfam PF00720 Subtilisin inhibitor-like 38 110 4.6E-23 T 14-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 A4R43_39615 9bf517c4f94f83b38c34a7ea26e28bb3 124 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 48 75 2.6E-9 T 14-10-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 A4R43_39615 9bf517c4f94f83b38c34a7ea26e28bb3 124 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 99 115 2.6E-9 T 14-10-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 A4R43_10850 84799742bbc68217b6f368326798981d 311 Pfam PF13614 AAA domain 1 178 1.8E-32 T 14-10-2018 IPR025669 AAA domain A4R43_10850 84799742bbc68217b6f368326798981d 311 SUPERFAMILY SSF52540 1 263 2.38E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10850 84799742bbc68217b6f368326798981d 311 Gene3D G3DSA:3.40.50.300 4 277 5.3E-49 T 14-10-2018 A4R43_17640 1d7dcfe1e63540478f882823c9a460eb 378 Gene3D G3DSA:3.90.1720.10 180 377 8.5E-51 T 14-10-2018 A4R43_17640 1d7dcfe1e63540478f882823c9a460eb 378 SUPERFAMILY SSF54001 262 377 6.54E-43 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_17640 1d7dcfe1e63540478f882823c9a460eb 378 Pfam PF00877 NlpC/P60 family 279 375 3.1E-28 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_07405 05315462649a807a13747d42c57aa1ae 354 Pfam PF00294 pfkB family carbohydrate kinase 50 303 1.4E-28 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_07405 05315462649a807a13747d42c57aa1ae 354 SUPERFAMILY SSF53613 17 312 4.37E-52 T 14-10-2018 IPR029056 Ribokinase-like A4R43_07405 05315462649a807a13747d42c57aa1ae 354 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_07405 05315462649a807a13747d42c57aa1ae 354 Gene3D G3DSA:3.40.1190.20 15 316 3.5E-55 T 14-10-2018 IPR029056 Ribokinase-like A4R43_04180 32862e46ee0d06946f5c1378ea6dda1b 222 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4R43_04180 32862e46ee0d06946f5c1378ea6dda1b 222 Gene3D G3DSA:1.20.120.1760 7 204 4.8E-56 T 14-10-2018 A4R43_04180 32862e46ee0d06946f5c1378ea6dda1b 222 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 2.4E-10 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4R43_20800 b646a2bc9c2c457b4794d58f1ba828d3 193 Pfam PF01872 RibD C-terminal domain 7 170 1.3E-14 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_20800 b646a2bc9c2c457b4794d58f1ba828d3 193 Gene3D G3DSA:3.40.430.10 3 178 5.7E-28 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_20800 b646a2bc9c2c457b4794d58f1ba828d3 193 SUPERFAMILY SSF53597 7 179 2.62E-20 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_10870 725c8a0ce0925e0612678b26bbc5daf8 256 SUPERFAMILY SSF53335 35 218 1.51E-19 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_10870 725c8a0ce0925e0612678b26bbc5daf8 256 Pfam PF13489 Methyltransferase domain 72 198 1.5E-11 T 14-10-2018 A4R43_10870 725c8a0ce0925e0612678b26bbc5daf8 256 Gene3D G3DSA:3.40.50.150 74 234 7.5E-18 T 14-10-2018 A4R43_12270 619a70ceec9904f342af14694267d6bf 198 Gene3D G3DSA:1.10.287.1060 4 100 3.9E-10 T 14-10-2018 A4R43_12270 619a70ceec9904f342af14694267d6bf 198 SUPERFAMILY SSF140453 6 98 1.83E-7 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_25580 5901715ab7328a6a75312416a1f53417 408 Gene3D G3DSA:1.20.1250.20 9 395 9.9E-33 T 14-10-2018 A4R43_25580 5901715ab7328a6a75312416a1f53417 408 Pfam PF05977 Transmembrane secretion effector 5 394 2.2E-35 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_25580 5901715ab7328a6a75312416a1f53417 408 SUPERFAMILY SSF103473 9 396 6.41E-35 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18750 3f7913cea96b82d1d21b9b52d6a6b632 150 Pfam PF01638 HxlR-like helix-turn-helix 20 106 5.3E-19 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_18750 3f7913cea96b82d1d21b9b52d6a6b632 150 Gene3D G3DSA:1.10.10.10 4 150 1.1E-43 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18750 3f7913cea96b82d1d21b9b52d6a6b632 150 SUPERFAMILY SSF46785 6 144 5.93E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08075 3c3d01ca7560abbddd781e9f1b94a5d3 153 Pfam PF14325 Domain of unknown function (DUF4383) 11 132 7.9E-42 T 14-10-2018 IPR025492 Protein of unknown function DUF4383 A4R43_15850 dc5397f963c6b34276e4ca43df42e2a7 554 ProSitePatterns PS00163 Fumarate lyases signature. 461 470 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A4R43_15850 dc5397f963c6b34276e4ca43df42e2a7 554 PIRSF PIRSF001394 32 551 4.4E-214 T 14-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 A4R43_15850 dc5397f963c6b34276e4ca43df42e2a7 554 SUPERFAMILY SSF117457 366 540 3.79E-61 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A4R43_15850 dc5397f963c6b34276e4ca43df42e2a7 554 Pfam PF05683 Fumarase C-terminus 337 542 1.6E-92 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4R43_15850 dc5397f963c6b34276e4ca43df42e2a7 554 Pfam PF05681 Fumarate hydratase (Fumerase) 51 331 1.5E-82 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A4R43_15850 dc5397f963c6b34276e4ca43df42e2a7 554 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 377 542 7.4E-57 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4R43_15850 dc5397f963c6b34276e4ca43df42e2a7 554 Gene3D G3DSA:3.20.130.10 353 541 2.5E-59 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A4R43_28825 ecd6eb0678f82a8a787149043c799d91 193 Gene3D G3DSA:1.10.357.10 2 192 4.1E-57 T 14-10-2018 A4R43_28825 ecd6eb0678f82a8a787149043c799d91 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 1.7E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28825 ecd6eb0678f82a8a787149043c799d91 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 4.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28825 ecd6eb0678f82a8a787149043c799d91 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 4.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28825 ecd6eb0678f82a8a787149043c799d91 193 SUPERFAMILY SSF48498 83 165 5.93E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_28825 ecd6eb0678f82a8a787149043c799d91 193 SUPERFAMILY SSF46689 11 80 2.0E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38025 bc0641c3d85e77bb2b08ac47c3e9bc9a 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 4.8E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38025 bc0641c3d85e77bb2b08ac47c3e9bc9a 186 SUPERFAMILY SSF46689 2 65 1.74E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38025 bc0641c3d85e77bb2b08ac47c3e9bc9a 186 SUPERFAMILY SSF48498 79 183 8.0E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_38025 bc0641c3d85e77bb2b08ac47c3e9bc9a 186 Gene3D G3DSA:1.10.357.10 62 186 5.3E-30 T 14-10-2018 A4R43_38025 bc0641c3d85e77bb2b08ac47c3e9bc9a 186 Gene3D G3DSA:1.10.10.60 4 61 2.6E-20 T 14-10-2018 A4R43_38025 bc0641c3d85e77bb2b08ac47c3e9bc9a 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 4.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38025 bc0641c3d85e77bb2b08ac47c3e9bc9a 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 4.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06265 5234d4943237dc93b562232c3a4f60cc 207 Gene3D G3DSA:3.40.50.2020 2 200 2.4E-68 T 14-10-2018 A4R43_06265 5234d4943237dc93b562232c3a4f60cc 207 Pfam PF00156 Phosphoribosyl transferase domain 8 186 1.9E-23 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4R43_06265 5234d4943237dc93b562232c3a4f60cc 207 SUPERFAMILY SSF53271 1 205 2.1E-41 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_06265 5234d4943237dc93b562232c3a4f60cc 207 Gene3D G3DSA:3.30.1310.20 51 112 2.4E-68 T 14-10-2018 A4R43_29150 3fae8f2b75d004c9a6e7c64ca4c15aa1 327 SUPERFAMILY SSF144091 87 271 1.03E-43 T 14-10-2018 A4R43_29150 3fae8f2b75d004c9a6e7c64ca4c15aa1 327 Pfam PF01694 Rhomboid family 138 268 4.3E-31 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4R43_29150 3fae8f2b75d004c9a6e7c64ca4c15aa1 327 Gene3D G3DSA:1.20.1540.10 85 279 2.0E-39 T 14-10-2018 IPR035952 Rhomboid-like superfamily A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 SUPERFAMILY SSF46785 3 70 3.73E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 SUPERFAMILY SSF64288 55 234 2.2E-39 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 5.5E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 5.5E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 Gene3D G3DSA:1.10.10.10 1 73 1.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 3.3E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 SMART SM00345 8 67 2.9E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 Gene3D G3DSA:3.40.1410.10 74 236 1.9E-37 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 Pfam PF07702 UTRA domain 90 224 6.9E-33 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_03760 709b27f1cd53caf4b0d67da4c2898b18 243 SMART SM00866 88 227 2.0E-29 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_41475 bdb9a80672b266133dac3543a930e51d 237 Gene3D G3DSA:2.40.10.10 12 236 4.3E-49 T 14-10-2018 A4R43_41475 bdb9a80672b266133dac3543a930e51d 237 SMART SM00020 15 231 1.1E-44 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_41475 bdb9a80672b266133dac3543a930e51d 237 SUPERFAMILY SSF50494 6 234 8.31E-53 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_41475 bdb9a80672b266133dac3543a930e51d 237 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 51 56 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4R43_41475 bdb9a80672b266133dac3543a930e51d 237 Pfam PF00089 Trypsin 16 231 3.2E-43 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_41475 bdb9a80672b266133dac3543a930e51d 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 41 56 1.4E-12 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_41475 bdb9a80672b266133dac3543a930e51d 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 96 110 1.4E-12 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_41475 bdb9a80672b266133dac3543a930e51d 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 179 191 1.4E-12 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_08680 ec88a2184c9509e4b01c62b3386f61bf 189 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 60 185 4.8E-21 T 14-10-2018 IPR005247 YbhB/YbcL A4R43_08680 ec88a2184c9509e4b01c62b3386f61bf 189 Pfam PF01161 Phosphatidylethanolamine-binding protein 58 187 1.9E-24 T 14-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A4R43_08680 ec88a2184c9509e4b01c62b3386f61bf 189 Gene3D G3DSA:3.90.280.10 17 188 4.9E-38 T 14-10-2018 IPR036610 PEBP-like superfamily A4R43_08680 ec88a2184c9509e4b01c62b3386f61bf 189 SUPERFAMILY SSF49777 30 185 2.62E-27 T 14-10-2018 IPR036610 PEBP-like superfamily A4R43_18540 cd71f53242fe508db2066530f98491bb 158 SUPERFAMILY SSF51735 6 135 4.43E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_18540 cd71f53242fe508db2066530f98491bb 158 Gene3D G3DSA:3.40.50.720 4 141 2.1E-34 T 14-10-2018 A4R43_18540 cd71f53242fe508db2066530f98491bb 158 SMART SM00881 14 107 3.5E-16 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_18540 cd71f53242fe508db2066530f98491bb 158 Pfam PF13380 CoA binding domain 20 133 3.6E-35 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 SMART SM00345 10 68 7.2E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 Pfam PF07729 FCD domain 78 200 1.5E-19 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 68 9.9E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 SMART SM00895 78 202 1.2E-12 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 Gene3D G3DSA:1.10.10.10 1 67 3.0E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 5.2E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 5.2E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 SUPERFAMILY SSF48008 75 205 1.1E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 SUPERFAMILY SSF46785 7 72 9.73E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_27105 8b438a3288f4dd14a237f17ff7198c74 210 Gene3D G3DSA:1.20.120.530 68 207 4.7E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_20540 483d700ee0e80d113f2eb400ac4dc84e 197 SUPERFAMILY SSF46689 11 72 4.81E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_20540 483d700ee0e80d113f2eb400ac4dc84e 197 SUPERFAMILY SSF48498 83 196 1.61E-24 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_20540 483d700ee0e80d113f2eb400ac4dc84e 197 Gene3D G3DSA:1.10.357.10 59 197 9.7E-32 T 14-10-2018 A4R43_20540 483d700ee0e80d113f2eb400ac4dc84e 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20540 483d700ee0e80d113f2eb400ac4dc84e 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20540 483d700ee0e80d113f2eb400ac4dc84e 197 Gene3D G3DSA:1.10.10.60 5 58 2.0E-24 T 14-10-2018 A4R43_20540 483d700ee0e80d113f2eb400ac4dc84e 197 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 190 2.5E-27 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_20540 483d700ee0e80d113f2eb400ac4dc84e 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 2.9E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 SUPERFAMILY SSF51735 8 249 3.33E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 5.3E-51 T 14-10-2018 A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 Gene3D G3DSA:3.40.50.720 2 251 2.4E-68 T 14-10-2018 A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_32205 84730754d9a6c7baf9572a1d6accca25 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19360 0dddbb8d34d04e30bc0fc9d6f4bbe907 135 SUPERFAMILY SSF69118 5 123 2.09E-35 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_19360 0dddbb8d34d04e30bc0fc9d6f4bbe907 135 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 4 124 1.1E-49 T 14-10-2018 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 A4R43_19360 0dddbb8d34d04e30bc0fc9d6f4bbe907 135 Gene3D G3DSA:1.20.1290.10 5 126 3.6E-39 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_19360 0dddbb8d34d04e30bc0fc9d6f4bbe907 135 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 118 1.2E-23 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_40610 4906c8b64fb87a30cc8a7e32ac4b7895 543 Gene3D G3DSA:3.50.50.60 54 539 2.3E-186 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40610 4906c8b64fb87a30cc8a7e32ac4b7895 543 SUPERFAMILY SSF51905 54 541 1.24E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40610 4906c8b64fb87a30cc8a7e32ac4b7895 543 SUPERFAMILY SSF54373 359 487 5.49E-43 T 14-10-2018 A4R43_40610 4906c8b64fb87a30cc8a7e32ac4b7895 543 Pfam PF05199 GMC oxidoreductase 482 533 1.4E-12 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4R43_40610 4906c8b64fb87a30cc8a7e32ac4b7895 543 Gene3D G3DSA:3.30.410.10 196 479 2.3E-186 T 14-10-2018 A4R43_11230 ff77d605d14382de934c2b2a2d8b263b 118 SUPERFAMILY SSF54427 1 114 2.04E-35 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_11230 ff77d605d14382de934c2b2a2d8b263b 118 Pfam PF12680 SnoaL-like domain 8 108 4.9E-15 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_11230 ff77d605d14382de934c2b2a2d8b263b 118 Gene3D G3DSA:3.10.450.50 1 116 1.5E-37 T 14-10-2018 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 Gene3D G3DSA:3.40.50.12740 11 216 8.7E-54 T 14-10-2018 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 Pfam PF00072 Response regulator receiver domain 13 124 2.2E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 SMART SM00448 11 124 5.0E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 SMART SM00421 153 210 1.4E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 SUPERFAMILY SSF46894 141 216 6.46E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 2.3E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 SUPERFAMILY SSF52172 10 136 3.42E-25 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_13725 314c72b84ae931b7c8fa646cd8c149bc 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28505 e983958c9a8172cdf223dbc9bb57a9a2 377 Pfam PF13581 Histidine kinase-like ATPase domain 284 346 4.7E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_28505 e983958c9a8172cdf223dbc9bb57a9a2 377 Pfam PF07730 Histidine kinase 178 244 5.1E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_28505 e983958c9a8172cdf223dbc9bb57a9a2 377 Pfam PF13185 GAF domain 25 161 5.2E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_28505 e983958c9a8172cdf223dbc9bb57a9a2 377 SUPERFAMILY SSF55781 25 165 1.33E-20 T 14-10-2018 A4R43_28505 e983958c9a8172cdf223dbc9bb57a9a2 377 SUPERFAMILY SSF55874 245 377 1.31E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_28505 e983958c9a8172cdf223dbc9bb57a9a2 377 Gene3D G3DSA:3.30.450.40 5 181 1.5E-25 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_28505 e983958c9a8172cdf223dbc9bb57a9a2 377 SMART SM00065 25 171 3.1E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_28505 e983958c9a8172cdf223dbc9bb57a9a2 377 Gene3D G3DSA:3.30.565.10 258 377 8.5E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_24120 4f092a348158264da8ad942ccd2d974e 422 PRINTS PR00095 Anthranilate synthase component I signature 259 272 1.1E-10 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_24120 4f092a348158264da8ad942ccd2d974e 422 PRINTS PR00095 Anthranilate synthase component I signature 273 286 1.1E-10 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_24120 4f092a348158264da8ad942ccd2d974e 422 PRINTS PR00095 Anthranilate synthase component I signature 366 380 1.1E-10 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_24120 4f092a348158264da8ad942ccd2d974e 422 PRINTS PR00095 Anthranilate synthase component I signature 351 365 1.1E-10 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_24120 4f092a348158264da8ad942ccd2d974e 422 Gene3D G3DSA:3.60.120.10 61 419 2.3E-104 T 14-10-2018 IPR005801 ADC synthase GO:0009058 A4R43_24120 4f092a348158264da8ad942ccd2d974e 422 Pfam PF00425 chorismate binding enzyme 162 409 1.1E-74 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A4R43_24120 4f092a348158264da8ad942ccd2d974e 422 SUPERFAMILY SSF56322 77 417 6.41E-95 T 14-10-2018 IPR005801 ADC synthase GO:0009058 A4R43_24120 4f092a348158264da8ad942ccd2d974e 422 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 81 413 1.9E-99 T 14-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 419 439 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 412 8.4E-70 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 455 5.6E-139 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 444 5.2E-26 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 SUPERFAMILY SSF55424 337 454 2.06E-30 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PIRSF PIRSF000350 2 442 9.3E-70 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 Gene3D G3DSA:3.50.50.60 7 322 4.2E-108 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 SUPERFAMILY SSF51905 3 360 2.16E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 Gene3D G3DSA:3.50.50.60 144 261 4.2E-108 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 Gene3D G3DSA:3.30.390.30 336 455 2.8E-33 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 5.0E-38 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 5.0E-38 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 5.0E-38 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 5.0E-38 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 5.0E-38 T 14-10-2018 A4R43_17820 e1a77561d649507926a2b01e0a98ceff 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 317 1.2E-72 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_38440 40fb5fec7ee71db222ba4c1647ce85c0 547 SMART SM00382 358 544 5.1E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_38440 40fb5fec7ee71db222ba4c1647ce85c0 547 SUPERFAMILY SSF52540 324 545 2.61E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38440 40fb5fec7ee71db222ba4c1647ce85c0 547 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_38440 40fb5fec7ee71db222ba4c1647ce85c0 547 Pfam PF00005 ABC transporter 349 497 7.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_38440 40fb5fec7ee71db222ba4c1647ce85c0 547 SUPERFAMILY SSF90123 6 314 3.14E-65 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_38440 40fb5fec7ee71db222ba4c1647ce85c0 547 Gene3D G3DSA:3.40.50.300 323 547 3.0E-71 T 14-10-2018 A4R43_38440 40fb5fec7ee71db222ba4c1647ce85c0 547 Pfam PF00664 ABC transporter transmembrane region 18 287 7.1E-31 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_38440 40fb5fec7ee71db222ba4c1647ce85c0 547 Gene3D G3DSA:1.20.1560.10 2 314 3.1E-74 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_30830 b4c86b2816468350a132759c3a33e0a8 191 SUPERFAMILY SSF46785 2 182 5.62E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_30830 b4c86b2816468350a132759c3a33e0a8 191 Gene3D G3DSA:1.10.10.10 1 105 1.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_30830 b4c86b2816468350a132759c3a33e0a8 191 Pfam PF03551 Transcriptional regulator PadR-like family 6 93 2.8E-14 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 220 1.7E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 Gene3D G3DSA:2.40.110.10 122 237 2.7E-34 T 14-10-2018 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 SUPERFAMILY SSF47203 231 386 1.21E-49 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 2.2E-24 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 Gene3D G3DSA:1.20.140.10 238 383 1.3E-41 T 14-10-2018 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 PIRSF PIRSF016578 237 387 1.6E-10 T 14-10-2018 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 PIRSF PIRSF016578 3 226 0.055 T 14-10-2018 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 Gene3D G3DSA:1.10.540.10 1 120 5.4E-30 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 2.0E-37 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_08265 0b67719cc5a30dd008a9288d23fc52a7 388 SUPERFAMILY SSF56645 2 246 1.14E-65 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_24335 a996d0b9296995affefd6f600733deab 299 Pfam PF00106 short chain dehydrogenase 9 206 1.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 Gene3D G3DSA:3.40.50.720 9 297 1.4E-69 T 14-10-2018 A4R43_24335 a996d0b9296995affefd6f600733deab 299 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 8.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 8.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 8.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 SUPERFAMILY SSF51735 2 255 5.76E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.9E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 2.9E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 2.9E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.9E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 2.9E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24335 a996d0b9296995affefd6f600733deab 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.9E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_27175 eebb8a5e0c47dddb764e6c479d84817f 416 Gene3D G3DSA:1.20.1250.20 284 415 8.5E-8 T 14-10-2018 A4R43_27175 eebb8a5e0c47dddb764e6c479d84817f 416 Gene3D G3DSA:1.20.1250.20 25 204 1.1E-10 T 14-10-2018 A4R43_27175 eebb8a5e0c47dddb764e6c479d84817f 416 SUPERFAMILY SSF103473 28 403 3.79E-24 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_27175 eebb8a5e0c47dddb764e6c479d84817f 416 Pfam PF07690 Major Facilitator Superfamily 28 341 6.0E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_23305 4278bde9313649b2ff32c8bb5822aacb 107 Pfam PF02467 Transcription factor WhiB 39 102 7.0E-27 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain A4R43_23305 4278bde9313649b2ff32c8bb5822aacb 107 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 14 107 19.283 T 14-10-2018 IPR003482 Transcription factor WhiB A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 Gene3D G3DSA:3.40.50.12740 3 217 3.4E-68 T 14-10-2018 A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 SUPERFAMILY SSF52172 2 136 2.85E-33 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 SMART SM00448 3 118 8.8E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 Pfam PF00072 Response regulator receiver domain 5 118 1.5E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 211 8.9E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 7.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 7.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 7.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 SMART SM00421 154 211 8.4E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28780 c35ca9a525b8e9bc4905210f2bb327dd 222 SUPERFAMILY SSF46894 141 217 5.44E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_01825 abe9185baecc1a0b5504dd46b690513d 385 Gene3D G3DSA:3.90.1150.10 257 380 5.0E-22 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_01825 abe9185baecc1a0b5504dd46b690513d 385 Gene3D G3DSA:3.40.640.10 1 256 1.5E-82 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_01825 abe9185baecc1a0b5504dd46b690513d 385 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 372 2.3E-90 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_01825 abe9185baecc1a0b5504dd46b690513d 385 SUPERFAMILY SSF53383 2 377 2.31E-89 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_01825 abe9185baecc1a0b5504dd46b690513d 385 PIRSF PIRSF000390 1 380 1.1E-87 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 SMART SM00823 Phosphopantetheine attachment site 492 564 0.0025 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 Pfam PF13193 AMP-binding enzyme C-terminal domain 398 466 1.4E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 Gene3D G3DSA:3.30.300.30 384 483 7.5E-28 T 14-10-2018 A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 Gene3D G3DSA:1.10.1200.10 487 566 1.1E-13 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 Gene3D G3DSA:3.40.50.12780 4 383 3.3E-105 T 14-10-2018 A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 SUPERFAMILY SSF56801 10 475 6.28E-127 T 14-10-2018 A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 Pfam PF00550 Phosphopantetheine attachment site 495 558 6.2E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 37 414 1.3E-108 T 14-10-2018 IPR010071 Amino acid adenylation domain A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 Pfam PF00501 AMP-binding enzyme 17 389 4.3E-79 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_04585 407f4d5aeb44415e9d2c91b3d3776581 566 SUPERFAMILY SSF47336 489 560 5.47E-10 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_34940 d76408dfb2594aba6aff079caa5c2885 235 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 32 224 1.6E-31 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_34940 d76408dfb2594aba6aff079caa5c2885 235 Pfam PF02096 60Kd inner membrane protein 33 224 2.7E-27 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4R43_18685 f9e35e640094b8645a00b05eb2f38a12 242 Gene3D G3DSA:3.40.50.2300 9 138 2.8E-37 T 14-10-2018 A4R43_18685 f9e35e640094b8645a00b05eb2f38a12 242 Gene3D G3DSA:1.10.10.10 139 241 1.8E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18685 f9e35e640094b8645a00b05eb2f38a12 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 240 1.2E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_18685 f9e35e640094b8645a00b05eb2f38a12 242 Pfam PF00072 Response regulator receiver domain 19 127 2.7E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_18685 f9e35e640094b8645a00b05eb2f38a12 242 SUPERFAMILY SSF52172 17 197 2.99E-41 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_18685 f9e35e640094b8645a00b05eb2f38a12 242 SMART SM00448 17 127 3.5E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_18685 f9e35e640094b8645a00b05eb2f38a12 242 SMART SM00862 164 240 1.6E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_07135 66584ae0ebbdbf8aad3ed8017f29b03c 379 PIRSF PIRSF037434 1 379 1.5E-71 T 14-10-2018 IPR017205 Signal transduction histidine kinase, ChrS A4R43_07135 66584ae0ebbdbf8aad3ed8017f29b03c 379 SMART SM00387 289 378 9.2E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_07135 66584ae0ebbdbf8aad3ed8017f29b03c 379 Pfam PF07730 Histidine kinase 187 251 2.3E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_07135 66584ae0ebbdbf8aad3ed8017f29b03c 379 Gene3D G3DSA:3.30.565.10 251 378 9.7E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_07135 66584ae0ebbdbf8aad3ed8017f29b03c 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 6.0E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_07135 66584ae0ebbdbf8aad3ed8017f29b03c 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 339 6.0E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_07135 66584ae0ebbdbf8aad3ed8017f29b03c 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 6.0E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_07135 66584ae0ebbdbf8aad3ed8017f29b03c 379 SUPERFAMILY SSF55874 258 377 3.01E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 101 125 4.5E-22 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 126 150 4.5E-22 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 153 167 4.5E-22 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 45 71 4.5E-22 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 40 166 4.1E-30 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 PIRSF PIRSF016573 12 180 6.0E-33 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 PIRSF PIRSF016573 4 39 10.0 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 SUPERFAMILY SSF55486 40 162 3.67E-20 T 14-10-2018 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 Gene3D G3DSA:3.40.390.10 38 168 1.1E-39 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A4R43_25875 f7429f815dac164c7326e36d97b9dcec 186 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 46 161 7.0E-38 T 14-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4R43_15115 11ad2887a1211fea4e62d0a56e957a2e 396 Gene3D G3DSA:1.10.150.130 10 118 3.4E-16 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_15115 11ad2887a1211fea4e62d0a56e957a2e 396 Gene3D G3DSA:1.10.443.10 142 348 1.4E-28 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_15115 11ad2887a1211fea4e62d0a56e957a2e 396 SUPERFAMILY SSF56349 12 342 5.0E-37 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_15115 11ad2887a1211fea4e62d0a56e957a2e 396 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 12 46 4.6E-5 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4R43_15115 11ad2887a1211fea4e62d0a56e957a2e 396 Pfam PF00589 Phage integrase family 151 335 6.7E-7 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_28225 1fb2c9b43bb52c02eea1078e45fccbc0 465 Gene3D G3DSA:3.40.50.12780 6 370 7.5E-68 T 14-10-2018 A4R43_28225 1fb2c9b43bb52c02eea1078e45fccbc0 465 Pfam PF00501 AMP-binding enzyme 13 374 3.6E-56 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_28225 1fb2c9b43bb52c02eea1078e45fccbc0 465 SUPERFAMILY SSF56801 18 463 1.96E-77 T 14-10-2018 A4R43_28225 1fb2c9b43bb52c02eea1078e45fccbc0 465 Gene3D G3DSA:3.30.300.30 376 465 9.7E-7 T 14-10-2018 A4R43_28225 1fb2c9b43bb52c02eea1078e45fccbc0 465 ProSitePatterns PS00455 Putative AMP-binding domain signature. 127 138 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_14595 deeafbd4b13ed3d8748d8899cd120e50 240 Gene3D G3DSA:1.10.10.60 125 230 2.3E-17 T 14-10-2018 A4R43_14595 deeafbd4b13ed3d8748d8899cd120e50 240 Pfam PF12833 Helix-turn-helix domain 152 225 2.5E-15 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_14595 deeafbd4b13ed3d8748d8899cd120e50 240 SMART SM00342 151 224 6.3E-8 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 Gene3D G3DSA:3.40.190.290 95 293 9.6E-42 T 14-10-2018 A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 SUPERFAMILY SSF53850 92 297 1.45E-42 T 14-10-2018 A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 SUPERFAMILY SSF46785 5 114 3.81E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 Pfam PF03466 LysR substrate binding domain 91 288 8.3E-43 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 Gene3D G3DSA:1.10.10.10 1 87 9.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12045 70d564949781ba7d099a5960d97fcbf1 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 8.1E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_34150 8f560966cf6df9c64a9aee16efaec5d7 270 Pfam PF12740 Chlorophyllase enzyme 33 157 1.0E-9 T 14-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 A4R43_34150 8f560966cf6df9c64a9aee16efaec5d7 270 Gene3D G3DSA:3.40.50.1820 2 266 8.7E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_34150 8f560966cf6df9c64a9aee16efaec5d7 270 SUPERFAMILY SSF53474 28 253 4.61E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_15410 32a65c55e6c8c2742a7cf55cd9338aa0 259 Pfam PF02720 Domain of unknown function (DUF222) 3 170 3.6E-18 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_26245 4534e0884359113288ef1b5e3f11c5ab 174 Gene3D G3DSA:3.30.1330.60 47 174 4.9E-21 T 14-10-2018 IPR036737 OmpA-like domain superfamily A4R43_26245 4534e0884359113288ef1b5e3f11c5ab 174 SUPERFAMILY SSF103088 73 173 1.7E-19 T 14-10-2018 IPR036737 OmpA-like domain superfamily A4R43_26245 4534e0884359113288ef1b5e3f11c5ab 174 Pfam PF00691 OmpA family 76 167 5.4E-14 T 14-10-2018 IPR006665 OmpA-like domain A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.3E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.3E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.3E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 Gene3D G3DSA:3.40.190.290 90 294 3.6E-49 T 14-10-2018 A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 SUPERFAMILY SSF46785 1 83 5.78E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 Gene3D G3DSA:1.10.10.10 1 83 6.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 Pfam PF03466 LysR substrate binding domain 89 290 2.2E-50 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08065 eabe209bcb6da4cb7b9b37f835b9db5b 298 SUPERFAMILY SSF53850 89 292 1.97E-48 T 14-10-2018 A4R43_02275 63a6cd4f35be2e938792868786d2d031 309 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 62 174 1.4E-4 T 14-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal A4R43_02275 63a6cd4f35be2e938792868786d2d031 309 SUPERFAMILY SSF53901 6 304 4.02E-25 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_02275 63a6cd4f35be2e938792868786d2d031 309 Gene3D G3DSA:3.40.47.10 190 305 7.2E-10 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_02275 63a6cd4f35be2e938792868786d2d031 309 Gene3D G3DSA:3.40.47.10 41 179 7.2E-21 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_30235 ed72996266949fe57ca5276ca978352b 414 Pfam PF00872 Transposase, Mutator family 23 381 1.1E-116 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4R43_30235 ed72996266949fe57ca5276ca978352b 414 ProSitePatterns PS01007 Transposases, Mutator family, signature. 240 264 - T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4R43_29760 ed72996266949fe57ca5276ca978352b 414 Pfam PF00872 Transposase, Mutator family 23 381 1.1E-116 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4R43_29760 ed72996266949fe57ca5276ca978352b 414 ProSitePatterns PS01007 Transposases, Mutator family, signature. 240 264 - T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4R43_00685 45750bdb7dac93306e092e3109635f37 303 SUPERFAMILY SSF51735 114 232 9.16E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_00685 45750bdb7dac93306e092e3109635f37 303 Pfam PF13602 Zinc-binding dehydrogenase 198 301 1.8E-15 T 14-10-2018 A4R43_00685 45750bdb7dac93306e092e3109635f37 303 SUPERFAMILY SSF50129 1 149 1.73E-26 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_00685 45750bdb7dac93306e092e3109635f37 303 Gene3D G3DSA:3.40.50.720 124 252 4.2E-67 T 14-10-2018 A4R43_00685 45750bdb7dac93306e092e3109635f37 303 SMART SM00829 10 301 5.1E-11 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_00685 45750bdb7dac93306e092e3109635f37 303 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 5.9E-8 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_00685 45750bdb7dac93306e092e3109635f37 303 Gene3D G3DSA:3.90.180.10 8 300 4.2E-67 T 14-10-2018 A4R43_08920 626cc385460cfe32e978e17695c05247 263 Gene3D G3DSA:3.40.50.720 1 257 1.1E-24 T 14-10-2018 A4R43_08920 626cc385460cfe32e978e17695c05247 263 Pfam PF00106 short chain dehydrogenase 2 121 1.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08920 626cc385460cfe32e978e17695c05247 263 SUPERFAMILY SSF51735 1 190 2.23E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_02155 29fdfd7ddc0691be6aa4c9e643d20992 72 Gene3D G3DSA:3.30.1540.10 2 67 9.1E-13 T 14-10-2018 A4R43_02155 29fdfd7ddc0691be6aa4c9e643d20992 72 Pfam PF02515 CoA-transferase family III 2 71 1.2E-9 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_02155 29fdfd7ddc0691be6aa4c9e643d20992 72 SUPERFAMILY SSF89796 2 71 5.89E-10 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 Gene3D G3DSA:3.40.50.300 1 234 9.3E-56 T 14-10-2018 A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 SUPERFAMILY SSF52540 5 225 2.92E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 SMART SM00382 284 478 2.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 SMART SM00382 31 220 4.0E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 Gene3D G3DSA:3.40.50.300 269 495 1.2E-45 T 14-10-2018 A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 SUPERFAMILY SSF52540 275 490 7.0E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 Pfam PF00005 ABC transporter 276 429 1.3E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_33750 59d0b5fd4ac360317264e8db111f4895 503 Pfam PF00005 ABC transporter 22 172 3.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 Gene3D G3DSA:2.60.120.260 355 535 6.6E-42 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 SUPERFAMILY SSF49785 291 530 5.95E-60 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 303 523 1.9E-56 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 SUPERFAMILY SSF53474 6 338 3.21E-74 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 SMART SM00939 291 549 2.4E-84 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 Gene3D G3DSA:3.40.50.1820 213 354 9.2E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 24 274 2.0E-60 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 Gene3D G3DSA:3.40.50.1820 2 205 2.4E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06230 b725aa9785a1e2df804412ce12ec967c 674 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 24 505 2.5E-61 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 A4R43_00520 6a81c850b992481b4821b14c3acb2c9c 291 SUPERFAMILY SSF52096 4 278 5.63E-36 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_00520 6a81c850b992481b4821b14c3acb2c9c 291 SMART SM00245 43 268 9.5E-9 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4R43_00520 6a81c850b992481b4821b14c3acb2c9c 291 Gene3D G3DSA:3.30.750.44 9 243 4.6E-61 T 14-10-2018 A4R43_00520 6a81c850b992481b4821b14c3acb2c9c 291 Pfam PF03572 Peptidase family S41 117 266 3.0E-20 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4R43_00520 6a81c850b992481b4821b14c3acb2c9c 291 Gene3D G3DSA:3.90.226.10 69 276 4.6E-61 T 14-10-2018 A4R43_36440 4d6a9dbd9ef3f05f33265f7a09e59b01 128 Gene3D G3DSA:3.30.565.10 2 127 8.3E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_36440 4d6a9dbd9ef3f05f33265f7a09e59b01 128 Pfam PF13581 Histidine kinase-like ATPase domain 7 123 7.1E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_36440 4d6a9dbd9ef3f05f33265f7a09e59b01 128 SUPERFAMILY SSF55874 25 125 5.31E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_26030 de0b9d0a36320b3a791e89bd63e30b3c 270 SUPERFAMILY SSF117396 1 265 4.58E-80 T 14-10-2018 IPR036520 UPF0759 superfamily A4R43_26030 de0b9d0a36320b3a791e89bd63e30b3c 270 Gene3D G3DSA:3.20.20.410 1 266 1.6E-67 T 14-10-2018 IPR036520 UPF0759 superfamily A4R43_26030 de0b9d0a36320b3a791e89bd63e30b3c 270 Pfam PF01904 Protein of unknown function DUF72 16 262 3.4E-70 T 14-10-2018 IPR002763 Protein of unknown function DUF72 A4R43_25400 b232b6b0dd3be486c01f729436f8f724 512 Gene3D G3DSA:3.40.50.12780 4 399 1.6E-101 T 14-10-2018 A4R43_25400 b232b6b0dd3be486c01f729436f8f724 512 Pfam PF00501 AMP-binding enzyme 15 403 2.0E-89 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_25400 b232b6b0dd3be486c01f729436f8f724 512 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 486 1.8E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_25400 b232b6b0dd3be486c01f729436f8f724 512 SUPERFAMILY SSF56801 10 496 1.02E-133 T 14-10-2018 A4R43_25400 b232b6b0dd3be486c01f729436f8f724 512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_25400 b232b6b0dd3be486c01f729436f8f724 512 Gene3D G3DSA:3.30.300.310 400 499 3.1E-27 T 14-10-2018 A4R43_10890 4929ecefab315e3974e6679348cc7a36 370 Gene3D G3DSA:1.20.1250.20 3 368 2.4E-39 T 14-10-2018 A4R43_10890 4929ecefab315e3974e6679348cc7a36 370 Pfam PF07690 Major Facilitator Superfamily 11 248 8.1E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_10890 4929ecefab315e3974e6679348cc7a36 370 PRINTS PR01035 Tetracycline resistance protein signature 73 97 4.9E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_10890 4929ecefab315e3974e6679348cc7a36 370 PRINTS PR01035 Tetracycline resistance protein signature 321 344 4.9E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_10890 4929ecefab315e3974e6679348cc7a36 370 PRINTS PR01035 Tetracycline resistance protein signature 131 153 4.9E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_10890 4929ecefab315e3974e6679348cc7a36 370 PRINTS PR01035 Tetracycline resistance protein signature 16 32 4.9E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_10890 4929ecefab315e3974e6679348cc7a36 370 SUPERFAMILY SSF103473 6 368 1.31E-44 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_38400 10208533ac85f6280aac40e2c0e6f9c2 334 SUPERFAMILY SSF56747 127 183 5.89E-5 T 14-10-2018 A4R43_38400 10208533ac85f6280aac40e2c0e6f9c2 334 Gene3D G3DSA:3.90.920.30 21 302 5.3E-91 T 14-10-2018 A4R43_38400 10208533ac85f6280aac40e2c0e6f9c2 334 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 14 259 2.9E-67 T 14-10-2018 IPR014145 DNA ligase D, polymerase domain A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 Gene3D G3DSA:3.40.50.1220 179 331 2.3E-42 T 14-10-2018 A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 Gene3D G3DSA:3.40.50.970 1 174 1.0E-56 T 14-10-2018 A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 316 1.6E-28 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 525 9.2E-37 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 SUPERFAMILY SSF52518 2 178 1.59E-43 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 SUPERFAMILY SSF52467 182 341 8.18E-40 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 1.2E-42 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 SUPERFAMILY SSF52518 357 542 2.03E-56 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_06080 014b8e69c3b6b831127a2ea4ab11db8c 577 Gene3D G3DSA:3.40.50.970 352 573 9.3E-61 T 14-10-2018 A4R43_23745 e87242968b029fdcdd76d81c49c4c672 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A4R43_23745 e87242968b029fdcdd76d81c49c4c672 406 Pfam PF02803 Thiolase, C-terminal domain 283 404 5.7E-48 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_23745 e87242968b029fdcdd76d81c49c4c672 406 SUPERFAMILY SSF53901 3 282 4.26E-65 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_23745 e87242968b029fdcdd76d81c49c4c672 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 8.5E-58 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_23745 e87242968b029fdcdd76d81c49c4c672 406 Gene3D G3DSA:3.40.47.10 2 405 5.1E-132 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_23745 e87242968b029fdcdd76d81c49c4c672 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 5.1E-137 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_23745 e87242968b029fdcdd76d81c49c4c672 406 SUPERFAMILY SSF53901 283 404 1.9E-43 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_23745 e87242968b029fdcdd76d81c49c4c672 406 PIRSF PIRSF000429 1 406 1.4E-126 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_29575 6dc1e41cdfd7eadca9bbdac74bc6182d 379 Gene3D G3DSA:3.40.50.2000 204 369 2.8E-20 T 14-10-2018 A4R43_29575 6dc1e41cdfd7eadca9bbdac74bc6182d 379 Pfam PF13439 Glycosyltransferase Family 4 24 179 1.0E-9 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_29575 6dc1e41cdfd7eadca9bbdac74bc6182d 379 Gene3D G3DSA:3.40.50.2000 9 203 2.8E-10 T 14-10-2018 A4R43_29575 6dc1e41cdfd7eadca9bbdac74bc6182d 379 Pfam PF00534 Glycosyl transferases group 1 204 330 1.5E-15 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_29575 6dc1e41cdfd7eadca9bbdac74bc6182d 379 SUPERFAMILY SSF53756 10 377 1.06E-36 T 14-10-2018 A4R43_10225 07bb754b1a2e8358dd142ab138c08cc1 431 SUPERFAMILY SSF51735 11 131 2.21E-9 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_10225 07bb754b1a2e8358dd142ab138c08cc1 431 Gene3D G3DSA:3.40.50.720 6 137 2.2E-11 T 14-10-2018 A4R43_10225 07bb754b1a2e8358dd142ab138c08cc1 431 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 70 129 4.3E-6 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A4R43_07620 fcf961426cb97f853253eab006281f28 223 SUPERFAMILY SSF48371 5 220 2.01E-65 T 14-10-2018 IPR016024 Armadillo-type fold A4R43_07620 fcf961426cb97f853253eab006281f28 223 Pfam PF08713 DNA alkylation repair enzyme 9 196 1.8E-23 T 14-10-2018 IPR014825 DNA alkylation repair enzyme A4R43_21015 517161f630461843a585ecea79627c52 237 Pfam PF00005 ABC transporter 22 149 4.4E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_21015 517161f630461843a585ecea79627c52 237 Gene3D G3DSA:3.40.50.300 1 224 4.6E-59 T 14-10-2018 A4R43_21015 517161f630461843a585ecea79627c52 237 SMART SM00382 31 199 1.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_21015 517161f630461843a585ecea79627c52 237 SUPERFAMILY SSF52540 6 221 1.89E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_02600 36adbb63b6a2d79a87ab2d35c9a2c6bb 301 Gene3D G3DSA:3.30.1330.60 153 301 7.2E-19 T 14-10-2018 IPR036737 OmpA-like domain superfamily A4R43_02600 36adbb63b6a2d79a87ab2d35c9a2c6bb 301 Gene3D G3DSA:1.25.40.10 8 90 2.8E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_02600 36adbb63b6a2d79a87ab2d35c9a2c6bb 301 SUPERFAMILY SSF103088 196 300 2.75E-14 T 14-10-2018 IPR036737 OmpA-like domain superfamily A4R43_02600 36adbb63b6a2d79a87ab2d35c9a2c6bb 301 Pfam PF00691 OmpA family 196 292 5.5E-9 T 14-10-2018 IPR006665 OmpA-like domain A4R43_02600 36adbb63b6a2d79a87ab2d35c9a2c6bb 301 SUPERFAMILY SSF48452 14 84 1.67E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_00945 266128008865c3318182b4c5b371676f 256 Gene3D G3DSA:3.30.450.40 75 252 4.4E-36 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_00945 266128008865c3318182b4c5b371676f 256 Pfam PF09339 IclR helix-turn-helix domain 9 59 2.7E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_00945 266128008865c3318182b4c5b371676f 256 SMART SM00346 6 97 4.5E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_00945 266128008865c3318182b4c5b371676f 256 Pfam PF01614 Bacterial transcriptional regulator 132 245 2.1E-14 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_00945 266128008865c3318182b4c5b371676f 256 SUPERFAMILY SSF46785 9 80 1.84E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00945 266128008865c3318182b4c5b371676f 256 SUPERFAMILY SSF55781 72 252 5.49E-36 T 14-10-2018 A4R43_00945 266128008865c3318182b4c5b371676f 256 Gene3D G3DSA:1.10.10.10 7 69 1.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27185 78a0f2806048312fb3ee5f2bbafae9b4 137 SUPERFAMILY SSF88723 8 126 7.85E-17 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_27185 78a0f2806048312fb3ee5f2bbafae9b4 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 8 132 10.239 T 14-10-2018 IPR022907 VapC family GO:0004540 A4R43_27185 78a0f2806048312fb3ee5f2bbafae9b4 137 Pfam PF01850 PIN domain 10 118 1.4E-7 T 14-10-2018 IPR002716 PIN domain A4R43_27185 78a0f2806048312fb3ee5f2bbafae9b4 137 Gene3D G3DSA:3.40.50.1010 6 133 1.6E-26 T 14-10-2018 A4R43_36635 32d58125a1010b4021a30b065d7f8ed5 328 Gene3D G3DSA:3.40.50.2000 148 313 1.6E-9 T 14-10-2018 A4R43_36635 32d58125a1010b4021a30b065d7f8ed5 328 SUPERFAMILY SSF53756 12 328 4.81E-15 T 14-10-2018 A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 Gene3D G3DSA:1.10.3140.10 14 151 4.5E-47 T 14-10-2018 A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 PIRSF PIRSF000331 11 499 1.2E-208 T 14-10-2018 IPR004925 HpaB/PvcC/4-BUDH A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 289 487 2.3E-68 T 14-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 Gene3D G3DSA:1.20.140.10 286 476 6.9E-77 T 14-10-2018 A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 SUPERFAMILY SSF47203 270 492 1.15E-52 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 15 279 5.9E-97 T 14-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 Gene3D G3DSA:2.40.110.10 153 281 3.9E-38 T 14-10-2018 A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 PIRSF PIRSF500125 1 516 1.2E-269 T 14-10-2018 IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein A4R43_37265 0fea7deaf1d11f5eb61cc1683ff0a293 520 SUPERFAMILY SSF56645 13 280 2.01E-83 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_25975 8221d87306bfca514850dd9590128fa7 159 SMART SM00960 31 121 4.5E-30 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_25975 8221d87306bfca514850dd9590128fa7 159 SUPERFAMILY SSF103196 26 147 7.32E-33 T 14-10-2018 A4R43_25975 8221d87306bfca514850dd9590128fa7 159 Pfam PF03259 Roadblock/LC7 domain 31 120 8.8E-25 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_25975 8221d87306bfca514850dd9590128fa7 159 Gene3D G3DSA:3.30.450.30 28 152 1.1E-41 T 14-10-2018 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 Gene3D G3DSA:3.30.9.50 72 286 1.4E-91 T 14-10-2018 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 Gene3D G3DSA:3.50.50.60 8 349 1.4E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 SUPERFAMILY SSF51905 5 377 1.78E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 Gene3D G3DSA:3.40.30.120 386 501 4.6E-20 T 14-10-2018 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 Pfam PF01494 FAD binding domain 7 351 2.4E-73 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 165 180 5.6E-41 T 14-10-2018 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 5.6E-41 T 14-10-2018 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 5.6E-41 T 14-10-2018 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 340 5.6E-41 T 14-10-2018 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 5.6E-41 T 14-10-2018 A4R43_00975 0a0e9edd6b0f04ba26cf0390d5c41229 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 5.6E-41 T 14-10-2018 A4R43_23110 c80c1af491d360742929c5a2f30b2875 161 Pfam PF00583 Acetyltransferase (GNAT) family 40 137 6.6E-16 T 14-10-2018 IPR000182 GNAT domain A4R43_23110 c80c1af491d360742929c5a2f30b2875 161 SUPERFAMILY SSF55729 4 152 1.08E-35 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_23110 c80c1af491d360742929c5a2f30b2875 161 Gene3D G3DSA:3.40.630.30 2 160 7.5E-48 T 14-10-2018 A4R43_17040 6104265418abc5747e82a796b8139635 294 Gene3D G3DSA:3.20.20.220 2 294 5.8E-93 T 14-10-2018 A4R43_17040 6104265418abc5747e82a796b8139635 294 Pfam PF02219 Methylenetetrahydrofolate reductase 7 288 2.3E-88 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A4R43_17040 6104265418abc5747e82a796b8139635 294 SUPERFAMILY SSF51730 3 290 9.22E-89 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 Gene3D G3DSA:1.10.287.130 152 218 4.0E-16 T 14-10-2018 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 351 2.1E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 370 2.1E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 327 2.1E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 210 224 2.1E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 Pfam PF00512 His Kinase A (phospho-acceptor) domain 153 218 2.1E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 SUPERFAMILY SSF55874 224 370 6.02E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 Pfam PF00672 HAMP domain 99 148 2.9E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 SMART SM00388 152 219 2.6E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 Gene3D G3DSA:3.30.565.10 223 373 4.8E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 SMART SM00304 98 151 8.2E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 262 371 4.4E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 SUPERFAMILY SSF158472 99 148 1.44E-7 T 14-10-2018 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 SUPERFAMILY SSF47384 137 217 6.87E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 Gene3D G3DSA:1.20.1480.50 59 151 1.1E-9 T 14-10-2018 A4R43_13915 ef4ba58753b48d421c7f206c12da704d 379 SMART SM00387 262 373 1.0E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_07455 cc437d25178236f2fc683d21025707aa 391 Gene3D G3DSA:3.40.50.720 166 350 1.3E-109 T 14-10-2018 A4R43_07455 cc437d25178236f2fc683d21025707aa 391 SMART SM00829 8 388 2.7E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_07455 cc437d25178236f2fc683d21025707aa 391 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_07455 cc437d25178236f2fc683d21025707aa 391 SUPERFAMILY SSF50129 1 193 6.54E-57 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_07455 cc437d25178236f2fc683d21025707aa 391 SUPERFAMILY SSF51735 153 351 2.37E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07455 cc437d25178236f2fc683d21025707aa 391 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 22 1.3E-9 T 14-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated A4R43_07455 cc437d25178236f2fc683d21025707aa 391 Gene3D G3DSA:3.90.180.10 4 378 1.3E-109 T 14-10-2018 A4R43_07455 cc437d25178236f2fc683d21025707aa 391 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 139 3.8E-26 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_07455 cc437d25178236f2fc683d21025707aa 391 Pfam PF00107 Zinc-binding dehydrogenase 187 258 1.4E-12 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_32970 584eee6107555506412ce9556ad1e1c2 257 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 20 235 1.3E-41 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A4R43_26970 475d941178c27ded50de753925f1d971 282 Pfam PF13365 Trypsin-like peptidase domain 43 210 3.4E-11 T 14-10-2018 A4R43_26970 475d941178c27ded50de753925f1d971 282 Gene3D G3DSA:2.40.10.10 136 222 7.2E-10 T 14-10-2018 A4R43_26970 475d941178c27ded50de753925f1d971 282 Gene3D G3DSA:2.40.10.10 50 135 7.2E-10 T 14-10-2018 A4R43_26970 475d941178c27ded50de753925f1d971 282 SUPERFAMILY SSF50494 15 225 7.35E-17 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_20715 f993608421a42c52eb723e807e3063cd 574 SUPERFAMILY SSF48452 33 216 2.07E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_20715 f993608421a42c52eb723e807e3063cd 574 Gene3D G3DSA:1.25.40.10 8 280 4.8E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_38265 788a0f7898deec2c4a9b34adcf94b971 512 Gene3D G3DSA:3.30.70.1230 326 511 1.6E-47 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_38265 788a0f7898deec2c4a9b34adcf94b971 512 SMART SM00044 303 498 1.3E-7 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4R43_38265 788a0f7898deec2c4a9b34adcf94b971 512 Pfam PF00672 HAMP domain 255 303 1.7E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_38265 788a0f7898deec2c4a9b34adcf94b971 512 SUPERFAMILY SSF158472 256 304 2.75E-6 T 14-10-2018 A4R43_38265 788a0f7898deec2c4a9b34adcf94b971 512 Gene3D G3DSA:1.10.287.130 253 325 8.6E-7 T 14-10-2018 A4R43_38265 788a0f7898deec2c4a9b34adcf94b971 512 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 335 506 5.0E-21 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4R43_38265 788a0f7898deec2c4a9b34adcf94b971 512 SUPERFAMILY SSF55073 331 509 7.85E-46 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_38265 788a0f7898deec2c4a9b34adcf94b971 512 SMART SM00304 255 307 2.9E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_26405 b2c2b7578cdfa3f2730da511ca506fb1 269 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 173 268 3.2E-27 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_26405 b2c2b7578cdfa3f2730da511ca506fb1 269 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 170 4.9E-49 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_26405 b2c2b7578cdfa3f2730da511ca506fb1 269 SUPERFAMILY SSF48179 172 268 1.02E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_26405 b2c2b7578cdfa3f2730da511ca506fb1 269 Gene3D G3DSA:3.40.50.720 1 175 3.2E-50 T 14-10-2018 A4R43_26405 b2c2b7578cdfa3f2730da511ca506fb1 269 SUPERFAMILY SSF51735 1 172 1.4E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_26405 b2c2b7578cdfa3f2730da511ca506fb1 269 Gene3D G3DSA:1.10.1040.10 176 269 3.4E-32 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_26405 b2c2b7578cdfa3f2730da511ca506fb1 269 PIRSF PIRSF000105 1 269 1.7E-68 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A4R43_20180 27479dc09ff332571829b311dd580a73 296 SUPERFAMILY SSF55469 4 78 2.49E-7 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_20180 27479dc09ff332571829b311dd580a73 296 Gene3D G3DSA:3.40.109.10 103 192 7.9E-12 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_20180 27479dc09ff332571829b311dd580a73 296 Gene3D G3DSA:3.40.109.10 193 290 2.9E-24 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_20180 27479dc09ff332571829b311dd580a73 296 Gene3D G3DSA:3.40.109.10 1 100 3.1E-36 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_20180 27479dc09ff332571829b311dd580a73 296 SUPERFAMILY SSF55469 111 289 9.16E-11 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_40210 0929fdb19cf1e897163234dfef29b79f 217 Gene3D G3DSA:1.10.357.10 20 213 1.6E-35 T 14-10-2018 A4R43_40210 0929fdb19cf1e897163234dfef29b79f 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 68 4.1E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40210 0929fdb19cf1e897163234dfef29b79f 217 SUPERFAMILY SSF46689 8 88 2.0E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00780 f3f085f7a4626a09691e6344cc3f528f 196 Pfam PF16859 Bacterial transcriptional repressor C-terminal 90 179 3.0E-18 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_00780 f3f085f7a4626a09691e6344cc3f528f 196 SUPERFAMILY SSF46689 4 68 5.49E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00780 f3f085f7a4626a09691e6344cc3f528f 196 SUPERFAMILY SSF48498 82 182 2.88E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_00780 f3f085f7a4626a09691e6344cc3f528f 196 Gene3D G3DSA:1.10.357.10 54 192 1.4E-21 T 14-10-2018 A4R43_00780 f3f085f7a4626a09691e6344cc3f528f 196 Gene3D G3DSA:1.10.10.60 1 53 2.1E-21 T 14-10-2018 A4R43_00780 f3f085f7a4626a09691e6344cc3f528f 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 6.1E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00780 f3f085f7a4626a09691e6344cc3f528f 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 6.7E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00780 f3f085f7a4626a09691e6344cc3f528f 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 6.7E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_18950 0ca1b01b4e7207bf0b2698fba62034b3 135 Pfam PF04075 F420H(2)-dependent quinone reductase 6 132 1.4E-48 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_18950 0ca1b01b4e7207bf0b2698fba62034b3 135 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 22 132 9.9E-36 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_18950 0ca1b01b4e7207bf0b2698fba62034b3 135 Gene3D G3DSA:2.30.110.10 2 133 8.0E-52 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_04420 2a14a84eefe74f1c10fe6d210948a991 243 Pfam PF02633 Creatinine amidohydrolase 10 234 1.2E-51 T 14-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_04420 2a14a84eefe74f1c10fe6d210948a991 243 Gene3D G3DSA:3.40.50.10310 3 240 8.6E-56 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_04420 2a14a84eefe74f1c10fe6d210948a991 243 SUPERFAMILY SSF102215 6 238 1.44E-50 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00385 P450 superfamily signature 234 251 5.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00385 P450 superfamily signature 269 280 5.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00385 P450 superfamily signature 337 346 5.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00385 P450 superfamily signature 346 357 5.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 Pfam PF00067 Cytochrome P450 175 368 1.9E-25 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 Pfam PF00067 Cytochrome P450 39 127 2.8E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 188 210 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 150 165 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 269 280 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 316 331 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 346 357 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 86 97 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 337 346 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 133 149 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 PRINTS PR00359 B-class P450 signature 288 315 1.7E-62 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 Gene3D G3DSA:1.10.630.10 8 394 2.5E-127 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_11880 89844a7ef4b24e397cab746805321354 394 SUPERFAMILY SSF48264 19 394 4.45E-101 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_19795 8b035e8a0f526c59842d01aaaf7eff82 445 Pfam PF07690 Major Facilitator Superfamily 56 342 7.7E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_19795 8b035e8a0f526c59842d01aaaf7eff82 445 Gene3D G3DSA:1.20.1250.20 15 440 3.6E-66 T 14-10-2018 A4R43_19795 8b035e8a0f526c59842d01aaaf7eff82 445 SUPERFAMILY SSF103473 18 423 1.01E-62 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_19075 3a7932b760a19c93a11f293cfda30d4d 393 Pfam PF00999 Sodium/hydrogen exchanger family 14 372 2.1E-54 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4R43_19075 3a7932b760a19c93a11f293cfda30d4d 393 Gene3D G3DSA:1.20.1530.20 3 383 1.0E-61 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily A4R43_11985 447785357f90a4fab5dd537c7c9c3dee 387 Gene3D G3DSA:3.30.420.40 82 366 4.2E-83 T 14-10-2018 A4R43_11985 447785357f90a4fab5dd537c7c9c3dee 387 SUPERFAMILY SSF46785 11 71 7.93E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_11985 447785357f90a4fab5dd537c7c9c3dee 387 ProSitePatterns PS01125 ROK family signature. 210 237 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_11985 447785357f90a4fab5dd537c7c9c3dee 387 Gene3D G3DSA:3.30.420.40 200 358 4.2E-83 T 14-10-2018 A4R43_11985 447785357f90a4fab5dd537c7c9c3dee 387 Pfam PF00480 ROK family 80 371 1.8E-53 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_11985 447785357f90a4fab5dd537c7c9c3dee 387 Gene3D G3DSA:1.10.10.10 10 71 5.4E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11985 447785357f90a4fab5dd537c7c9c3dee 387 SUPERFAMILY SSF53067 75 372 1.68E-53 T 14-10-2018 A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 8.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 8.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 8.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 SUPERFAMILY SSF51735 3 261 3.01E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 Gene3D G3DSA:3.40.50.720 2 292 6.7E-70 T 14-10-2018 A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 Pfam PF00106 short chain dehydrogenase 8 201 3.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_19605 75a4929484f4d233c9e227af0cac1292 294 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 205 2.8E-4 T 14-10-2018 A4R43_30915 8aef38cbd0a6e26a3ce90a326701a7ba 586 Gene3D G3DSA:3.30.565.10 454 579 1.7E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30915 8aef38cbd0a6e26a3ce90a326701a7ba 586 Pfam PF07730 Histidine kinase 375 438 1.1E-16 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_30915 8aef38cbd0a6e26a3ce90a326701a7ba 586 SMART SM00387 486 581 0.0038 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_30915 8aef38cbd0a6e26a3ce90a326701a7ba 586 SUPERFAMILY SSF55874 478 579 7.89E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30325 052fe99f5662b6dbf77d4fbde2616ff0 189 Pfam PF07508 Recombinase 72 168 6.2E-13 T 14-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A4R43_30325 052fe99f5662b6dbf77d4fbde2616ff0 189 Gene3D G3DSA:1.10.10.2600 23 173 3.4E-8 T 14-10-2018 IPR038109 DNA-binding recombinase domain superfamily A4R43_32215 1abe1bc85b9aae45cb441dd0987c3353 304 Pfam PF00892 EamA-like transporter family 156 286 2.3E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_32215 1abe1bc85b9aae45cb441dd0987c3353 304 Pfam PF00892 EamA-like transporter family 13 143 3.3E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_32215 1abe1bc85b9aae45cb441dd0987c3353 304 SUPERFAMILY SSF103481 190 293 2.22E-10 T 14-10-2018 A4R43_32215 1abe1bc85b9aae45cb441dd0987c3353 304 SUPERFAMILY SSF103481 45 146 4.05E-11 T 14-10-2018 A4R43_01775 23a8017cc820f164fc7e18db32016806 152 SUPERFAMILY SSF54593 3 144 4.26E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_01775 23a8017cc820f164fc7e18db32016806 152 Gene3D G3DSA:3.10.180.10 2 148 9.9E-50 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_01775 23a8017cc820f164fc7e18db32016806 152 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 130 2.0E-11 T 14-10-2018 A4R43_28850 a068263b3b1e987dcb7c0dc16be1f8ee 543 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 9 530 5.1E-60 T 14-10-2018 IPR019993 RecB family nuclease, TM0106, putative A4R43_28850 a068263b3b1e987dcb7c0dc16be1f8ee 543 Pfam PF13482 RNase_H superfamily 442 530 7.0E-12 T 14-10-2018 IPR038720 YprB, ribonuclease H-like domain A4R43_28850 a068263b3b1e987dcb7c0dc16be1f8ee 543 SUPERFAMILY SSF53098 449 533 9.26E-5 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_13385 ce777ca259d776340a60780ca090030c 325 SUPERFAMILY SSF46689 261 314 5.38E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13385 ce777ca259d776340a60780ca090030c 325 SMART SM00342 226 311 1.9E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_13385 ce777ca259d776340a60780ca090030c 325 Gene3D G3DSA:1.10.10.60 206 316 4.0E-29 T 14-10-2018 A4R43_13385 ce777ca259d776340a60780ca090030c 325 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 280 295 2.1E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_13385 ce777ca259d776340a60780ca090030c 325 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 311 2.1E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_13385 ce777ca259d776340a60780ca090030c 325 SUPERFAMILY SSF51182 61 130 4.45E-5 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_13385 ce777ca259d776340a60780ca090030c 325 Pfam PF12833 Helix-turn-helix domain 232 312 2.4E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_13385 ce777ca259d776340a60780ca090030c 325 Pfam PF14525 AraC-binding-like domain 19 192 1.1E-35 T 14-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like A4R43_13670 aa9eac03979e14a9fba4282d2f05c077 345 Pfam PF03969 AFG1-like ATPase 234 335 5.5E-13 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 A4R43_13670 aa9eac03979e14a9fba4282d2f05c077 345 Pfam PF03969 AFG1-like ATPase 39 222 5.5E-44 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 A4R43_13670 aa9eac03979e14a9fba4282d2f05c077 345 SUPERFAMILY SSF52540 81 213 2.97E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13670 aa9eac03979e14a9fba4282d2f05c077 345 Gene3D G3DSA:3.40.50.300 13 201 2.8E-14 T 14-10-2018 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 SMART SM00421 152 209 2.1E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 1.4E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 Pfam PF00072 Response regulator receiver domain 4 114 4.5E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 SMART SM00448 2 115 1.3E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 SUPERFAMILY SSF46894 141 215 1.97E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 Gene3D G3DSA:3.40.50.12740 2 215 5.4E-69 T 14-10-2018 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 SUPERFAMILY SSF52172 2 132 7.54E-36 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 8.7E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 8.7E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21830 632af4dd4dbc5cc39dc129cf274a0cf9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 8.7E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_04335 5d0f5b5e84d7a328e74a0164bbbcc120 140 SMART SM01323 2 85 8.0E-25 T 14-10-2018 IPR003849 Preprotein translocase YajC A4R43_04335 5d0f5b5e84d7a328e74a0164bbbcc120 140 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 7 85 1.1E-17 T 14-10-2018 IPR003849 Preprotein translocase YajC A4R43_04335 5d0f5b5e84d7a328e74a0164bbbcc120 140 Pfam PF02699 Preprotein translocase subunit 9 82 2.2E-18 T 14-10-2018 IPR003849 Preprotein translocase YajC A4R43_02905 c0e6b9bb495d3d9cffe50afc3dbdaa03 315 Gene3D G3DSA:3.30.2010.10 115 198 6.5E-8 T 14-10-2018 A4R43_02905 c0e6b9bb495d3d9cffe50afc3dbdaa03 315 Pfam PF01435 Peptidase family M48 145 196 9.6E-7 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 Gene3D G3DSA:3.30.565.10 307 450 2.3E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 SMART SM00304 182 234 9.9E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 Gene3D G3DSA:1.10.287.130 186 304 1.2E-26 T 14-10-2018 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 SUPERFAMILY SSF158472 182 231 4.97E-7 T 14-10-2018 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 SUPERFAMILY SSF47384 218 300 2.75E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 449 1.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 SUPERFAMILY SSF55874 292 447 5.76E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 Pfam PF00672 HAMP domain 182 231 6.8E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 301 2.6E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 SMART SM00387 340 450 7.4E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 SMART SM00388 235 302 2.3E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 8.9E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 8.9E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 403 8.9E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_01980 d2b5c1ac29cf23238435c09553128721 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 8.9E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_33610 aae4c3c81b82b3de6f1307fbdbff297b 443 Pfam PF02470 MlaD protein 37 111 2.1E-9 T 14-10-2018 IPR003399 Mce/MlaD A4R43_33610 aae4c3c81b82b3de6f1307fbdbff297b 443 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 293 7.5E-55 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33610 aae4c3c81b82b3de6f1307fbdbff297b 443 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 143 427 3.6E-72 T 14-10-2018 IPR024516 Mammalian cell entry, C-terminal A4R43_32005 b20e042b6c4deadf4d367f288d18efb6 272 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 172 1.8E-51 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_32005 b20e042b6c4deadf4d367f288d18efb6 272 Gene3D G3DSA:3.40.50.720 1 176 8.4E-55 T 14-10-2018 A4R43_32005 b20e042b6c4deadf4d367f288d18efb6 272 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 175 271 9.7E-31 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_32005 b20e042b6c4deadf4d367f288d18efb6 272 PIRSF PIRSF000105 1 272 1.5E-72 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A4R43_32005 b20e042b6c4deadf4d367f288d18efb6 272 SUPERFAMILY SSF51735 1 172 1.36E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_32005 b20e042b6c4deadf4d367f288d18efb6 272 SUPERFAMILY SSF48179 175 272 2.21E-29 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_32005 b20e042b6c4deadf4d367f288d18efb6 272 Gene3D G3DSA:1.10.1040.10 177 272 4.6E-31 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_27380 b3b11692960b052f3b3f6811c88cb09e 316 Pfam PF00892 EamA-like transporter family 141 282 1.6E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_27380 b3b11692960b052f3b3f6811c88cb09e 316 Pfam PF00892 EamA-like transporter family 7 130 5.1E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_27380 b3b11692960b052f3b3f6811c88cb09e 316 SUPERFAMILY SSF103481 43 133 1.57E-11 T 14-10-2018 A4R43_27380 b3b11692960b052f3b3f6811c88cb09e 316 SUPERFAMILY SSF103481 185 287 3.4E-10 T 14-10-2018 A4R43_25870 eca3a3a1bd3323ada6717a5c21015fea 124 Pfam PF03733 Inner membrane component domain 68 118 4.7E-18 T 14-10-2018 IPR005185 Inner membrane component domain A4R43_25870 eca3a3a1bd3323ada6717a5c21015fea 124 Pfam PF03733 Inner membrane component domain 4 54 3.6E-20 T 14-10-2018 IPR005185 Inner membrane component domain A4R43_25870 eca3a3a1bd3323ada6717a5c21015fea 124 PIRSF PIRSF028777 1 124 2.1E-50 T 14-10-2018 IPR031308 Uncharacterised conserved protein UCP028777 A4R43_29800 7ebe56032131344fe03bd99a16892eee 353 SUPERFAMILY SSF47203 201 326 1.05E-26 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_29800 7ebe56032131344fe03bd99a16892eee 353 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 206 307 3.2E-18 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_29800 7ebe56032131344fe03bd99a16892eee 353 Gene3D G3DSA:1.20.140.10 200 335 2.2E-24 T 14-10-2018 A4R43_29800 7ebe56032131344fe03bd99a16892eee 353 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 2 91 1.4E-8 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_29800 7ebe56032131344fe03bd99a16892eee 353 SUPERFAMILY SSF56645 2 183 8.38E-14 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_29800 7ebe56032131344fe03bd99a16892eee 353 Gene3D G3DSA:1.10.540.10 1 97 2.6E-15 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_26410 ea3921b5ab8be0abe6e1434036a62b63 127 Gene3D G3DSA:3.10.129.10 1 127 2.0E-48 T 14-10-2018 A4R43_26410 ea3921b5ab8be0abe6e1434036a62b63 127 Pfam PF03061 Thioesterase superfamily 39 111 1.7E-10 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_26410 ea3921b5ab8be0abe6e1434036a62b63 127 SUPERFAMILY SSF54637 4 120 7.04E-27 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_26410 ea3921b5ab8be0abe6e1434036a62b63 127 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 9 120 2.4E-41 T 14-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 A4R43_26410 ea3921b5ab8be0abe6e1434036a62b63 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 9 117 1.8E-19 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A4R43_38415 4e80b22d998dd72c5f50a1b64022c064 191 Gene3D G3DSA:1.10.3300.10 8 185 6.6E-27 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_38415 4e80b22d998dd72c5f50a1b64022c064 191 Pfam PF11706 CGNR zinc finger 140 181 4.4E-16 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_38415 4e80b22d998dd72c5f50a1b64022c064 191 SUPERFAMILY SSF160904 8 181 3.4E-40 T 14-10-2018 A4R43_38415 4e80b22d998dd72c5f50a1b64022c064 191 Pfam PF07336 Putative stress-induced transcription regulator 14 135 5.2E-18 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 SUPERFAMILY SSF53474 2 354 1.59E-100 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 Gene3D G3DSA:3.40.50.1820 1 357 5.8E-137 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 PRINTS PR00412 Epoxide hydrolase signature 176 189 7.6E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 PRINTS PR00412 Epoxide hydrolase signature 98 116 7.6E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 PRINTS PR00412 Epoxide hydrolase signature 300 316 7.6E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 PRINTS PR00412 Epoxide hydrolase signature 331 353 7.6E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 PRINTS PR00412 Epoxide hydrolase signature 162 175 7.6E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 Pfam PF06441 Epoxide hydrolase N terminus 2 107 3.8E-39 T 14-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 A4R43_08230 9f548b03949fd44fc03f0bec9bfaab9f 357 PIRSF PIRSF001112 1 356 4.9E-107 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_07270 515386624e3475e665a805d4765a8d84 110 SUPERFAMILY SSF54593 11 109 2.55E-14 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_07270 515386624e3475e665a805d4765a8d84 110 Gene3D G3DSA:3.10.180.10 2 110 1.1E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_05930 540abb30f7794515b72a60eb86ffae0b 159 Pfam PF10706 Aminoglycoside-2''-adenylyltransferase 6 90 2.7E-7 T 14-10-2018 IPR019646 Aminoglycoside-2''-adenylyltransferase A4R43_05930 540abb30f7794515b72a60eb86ffae0b 159 Gene3D G3DSA:3.30.460.40 1 152 3.3E-46 T 14-10-2018 A4R43_17510 fcb9173c31e8474ac3bdcb380a764034 106 Gene3D G3DSA:1.10.287.1060 1 89 4.3E-8 T 14-10-2018 A4R43_17510 fcb9173c31e8474ac3bdcb380a764034 106 SUPERFAMILY SSF140453 2 84 2.22E-8 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_34075 95dcffcc1ac3497877624bfe5f95eef9 221 Pfam PF14230 Domain of unknown function (DUF4333) 139 212 6.7E-23 T 14-10-2018 IPR025637 Domain of unknown function DUF4333 A4R43_22130 3ccf6fa5c6ad8e8f45e7b5e3c0c344dd 284 SUPERFAMILY SSF55729 15 271 4.63E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_22130 3ccf6fa5c6ad8e8f45e7b5e3c0c344dd 284 Pfam PF08445 FR47-like protein 195 271 7.2E-9 T 14-10-2018 IPR013653 FR47-like GO:0016747 A4R43_22130 3ccf6fa5c6ad8e8f45e7b5e3c0c344dd 284 Gene3D G3DSA:3.40.630.30 61 277 1.1E-23 T 14-10-2018 A4R43_23630 f7102cb415a7ca3b962530248dfd2a63 372 SUPERFAMILY SSF51905 4 352 1.01E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23630 f7102cb415a7ca3b962530248dfd2a63 372 Pfam PF01494 FAD binding domain 4 324 2.2E-14 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_23630 f7102cb415a7ca3b962530248dfd2a63 372 Gene3D G3DSA:3.50.50.60 1 361 3.4E-102 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23630 f7102cb415a7ca3b962530248dfd2a63 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.6E-12 T 14-10-2018 A4R43_23630 f7102cb415a7ca3b962530248dfd2a63 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.6E-12 T 14-10-2018 A4R43_23630 f7102cb415a7ca3b962530248dfd2a63 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.6E-12 T 14-10-2018 A4R43_06670 30d8940e51f351cdb70888a50d498256 196 Gene3D G3DSA:1.10.357.10 55 194 2.1E-19 T 14-10-2018 A4R43_06670 30d8940e51f351cdb70888a50d498256 196 Pfam PF16859 Bacterial transcriptional repressor C-terminal 73 185 3.4E-18 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_06670 30d8940e51f351cdb70888a50d498256 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 4.6E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06670 30d8940e51f351cdb70888a50d498256 196 Gene3D G3DSA:1.10.10.60 2 53 4.5E-17 T 14-10-2018 A4R43_06670 30d8940e51f351cdb70888a50d498256 196 SUPERFAMILY SSF46689 5 69 1.59E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_06670 30d8940e51f351cdb70888a50d498256 196 SUPERFAMILY SSF48498 74 192 7.26E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_17265 41b435ec3757696684a2b41c96552334 253 Pfam PF00977 Histidine biosynthesis protein 6 237 3.3E-86 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A4R43_17265 41b435ec3757696684a2b41c96552334 253 Gene3D G3DSA:3.20.20.70 1 253 6.3E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17265 41b435ec3757696684a2b41c96552334 253 SUPERFAMILY SSF51366 4 253 2.28E-80 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4R43_17265 41b435ec3757696684a2b41c96552334 253 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 253 47.975 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A4R43_17265 41b435ec3757696684a2b41c96552334 253 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 253 9.0E-114 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A4R43_11040 13db9184e8cb3a3e8ead7d90aa0f2a6d 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 1.1E-68 T 14-10-2018 A4R43_11040 13db9184e8cb3a3e8ead7d90aa0f2a6d 255 SUPERFAMILY SSF51735 6 252 4.34E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11040 13db9184e8cb3a3e8ead7d90aa0f2a6d 255 Gene3D G3DSA:3.40.50.720 2 253 2.6E-48 T 14-10-2018 A4R43_11040 13db9184e8cb3a3e8ead7d90aa0f2a6d 255 PIRSF PIRSF000094 2 255 3.2E-88 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A4R43_20110 a1c108522f7c5ab0ac541e28824c9fc8 131 SUPERFAMILY SSF55729 18 125 1.52E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_20110 a1c108522f7c5ab0ac541e28824c9fc8 131 Gene3D G3DSA:3.40.630.30 4 131 1.2E-32 T 14-10-2018 A4R43_20110 a1c108522f7c5ab0ac541e28824c9fc8 131 Pfam PF00583 Acetyltransferase (GNAT) family 20 120 2.1E-19 T 14-10-2018 IPR000182 GNAT domain A4R43_41330 6e1c8ff5ae27151e59e61b1318834f94 349 PIRSF PIRSF000164 14 349 4.5E-95 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A4R43_41330 6e1c8ff5ae27151e59e61b1318834f94 349 Gene3D G3DSA:3.20.20.70 3 344 6.1E-121 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_41330 6e1c8ff5ae27151e59e61b1318834f94 349 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 6 347 1.2E-111 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4R43_41330 6e1c8ff5ae27151e59e61b1318834f94 349 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 3 346 46.24 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4R43_41330 6e1c8ff5ae27151e59e61b1318834f94 349 SUPERFAMILY SSF51395 12 347 1.19E-92 T 14-10-2018 A4R43_41330 6e1c8ff5ae27151e59e61b1318834f94 349 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 86 105 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A4R43_41330 6e1c8ff5ae27151e59e61b1318834f94 349 Pfam PF01180 Dihydroorotate dehydrogenase 53 348 3.6E-85 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A4R43_03630 f393e9c20b00f6b03a2eef15f2e325fc 324 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_03630 f393e9c20b00f6b03a2eef15f2e325fc 324 Gene3D G3DSA:3.40.50.300 3 323 8.9E-99 T 14-10-2018 A4R43_03630 f393e9c20b00f6b03a2eef15f2e325fc 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 317 3.5E-24 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_03630 f393e9c20b00f6b03a2eef15f2e325fc 324 SMART SM00382 34 228 6.7E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03630 f393e9c20b00f6b03a2eef15f2e325fc 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 297 1.2E-16 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4R43_03630 f393e9c20b00f6b03a2eef15f2e325fc 324 Pfam PF00005 ABC transporter 25 178 2.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_03630 f393e9c20b00f6b03a2eef15f2e325fc 324 SUPERFAMILY SSF52540 5 249 1.7E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_18625 4d3fa79ac7169ea4ff3a7317ebf4caf5 403 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 170 278 3.9E-6 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_18625 4d3fa79ac7169ea4ff3a7317ebf4caf5 403 Gene3D G3DSA:3.20.20.60 68 333 1.3E-16 T 14-10-2018 A4R43_18625 4d3fa79ac7169ea4ff3a7317ebf4caf5 403 SUPERFAMILY SSF51621 79 328 7.01E-16 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_30470 94e7aaf8c1ce8d6a954760aa896c1b31 440 Pfam PF00155 Aminotransferase class I and II 61 407 2.2E-37 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_30470 94e7aaf8c1ce8d6a954760aa896c1b31 440 Gene3D G3DSA:3.90.1150.10 36 411 2.4E-134 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_30470 94e7aaf8c1ce8d6a954760aa896c1b31 440 Gene3D G3DSA:3.40.640.10 83 305 2.4E-134 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_30470 94e7aaf8c1ce8d6a954760aa896c1b31 440 SUPERFAMILY SSF53383 23 412 6.89E-108 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_24640 2ab46c77a0849eab590b39e46c67d1f2 233 Gene3D G3DSA:1.10.10.10 124 227 3.7E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_24640 2ab46c77a0849eab590b39e46c67d1f2 233 SMART SM00448 2 113 1.9E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_24640 2ab46c77a0849eab590b39e46c67d1f2 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 2.6E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_24640 2ab46c77a0849eab590b39e46c67d1f2 233 SMART SM00862 146 221 3.8E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_24640 2ab46c77a0849eab590b39e46c67d1f2 233 SUPERFAMILY SSF52172 1 179 2.2E-40 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_24640 2ab46c77a0849eab590b39e46c67d1f2 233 Pfam PF00072 Response regulator receiver domain 4 113 2.2E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_24640 2ab46c77a0849eab590b39e46c67d1f2 233 Gene3D G3DSA:3.40.50.2300 1 121 4.4E-40 T 14-10-2018 A4R43_12615 ed51e91244996f11b8c8de2668d59ee0 256 PIRSF PIRSF000094 1 256 2.2E-71 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A4R43_12615 ed51e91244996f11b8c8de2668d59ee0 256 Gene3D G3DSA:3.40.50.720 1 254 4.5E-48 T 14-10-2018 A4R43_12615 ed51e91244996f11b8c8de2668d59ee0 256 SUPERFAMILY SSF51735 5 254 1.37E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_12615 ed51e91244996f11b8c8de2668d59ee0 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 3.2E-63 T 14-10-2018 A4R43_06470 197eb981981b02d820c7dd243a7fef92 343 Gene3D G3DSA:3.40.50.2300 87 335 2.6E-69 T 14-10-2018 A4R43_06470 197eb981981b02d820c7dd243a7fef92 343 SUPERFAMILY SSF47413 12 70 8.57E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_06470 197eb981981b02d820c7dd243a7fef92 343 Gene3D G3DSA:3.40.50.2300 176 337 2.6E-69 T 14-10-2018 A4R43_06470 197eb981981b02d820c7dd243a7fef92 343 Gene3D G3DSA:1.10.260.40 5 69 8.8E-20 T 14-10-2018 A4R43_06470 197eb981981b02d820c7dd243a7fef92 343 SMART SM00354 12 82 2.2E-21 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_06470 197eb981981b02d820c7dd243a7fef92 343 Pfam PF13377 Periplasmic binding protein-like domain 184 342 3.9E-39 T 14-10-2018 A4R43_06470 197eb981981b02d820c7dd243a7fef92 343 SUPERFAMILY SSF53822 85 342 1.34E-64 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_06470 197eb981981b02d820c7dd243a7fef92 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 9.2E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_29490 7fe95d3ccf7f3ac10e5bc4d4a0ee1b81 306 Pfam PF10977 Protein of unknown function (DUF2797) 108 214 1.9E-10 T 14-10-2018 IPR021246 Protein of unknown function DUF2797 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 PRINTS PR00173 Glutamate-aspartate symporter signature 69 94 4.6E-29 T 14-10-2018 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 PRINTS PR00173 Glutamate-aspartate symporter signature 183 202 4.6E-29 T 14-10-2018 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 PRINTS PR00173 Glutamate-aspartate symporter signature 136 158 4.6E-29 T 14-10-2018 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 PRINTS PR00173 Glutamate-aspartate symporter signature 319 338 4.6E-29 T 14-10-2018 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 4.6E-29 T 14-10-2018 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 PRINTS PR00173 Glutamate-aspartate symporter signature 284 310 4.6E-29 T 14-10-2018 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 SUPERFAMILY SSF118215 4 393 3.79E-105 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 Pfam PF00375 Sodium:dicarboxylate symporter family 4 392 3.9E-100 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4R43_14470 dab5b8d3cb713f39d0cae03ddca23255 439 Gene3D G3DSA:1.10.3860.10 1 407 1.0E-109 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4R43_06395 dbd142ecd8143b64ed606beb11d85413 429 Pfam PF13416 Bacterial extracellular solute-binding protein 56 364 1.2E-29 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_06395 dbd142ecd8143b64ed606beb11d85413 429 Gene3D G3DSA:3.40.190.10 150 420 9.9E-107 T 14-10-2018 A4R43_06395 dbd142ecd8143b64ed606beb11d85413 429 SUPERFAMILY SSF53850 21 424 1.49E-65 T 14-10-2018 A4R43_06395 dbd142ecd8143b64ed606beb11d85413 429 Gene3D G3DSA:3.40.190.10 53 386 9.9E-107 T 14-10-2018 A4R43_18190 af2eca86e0dffb0b742ed81ec674470b 298 SUPERFAMILY SSF52283 52 112 5.53E-5 T 14-10-2018 A4R43_18190 af2eca86e0dffb0b742ed81ec674470b 298 Gene3D G3DSA:3.40.50.720 27 297 1.5E-72 T 14-10-2018 A4R43_18190 af2eca86e0dffb0b742ed81ec674470b 298 Gene3D G3DSA:3.40.50.720 91 273 1.5E-72 T 14-10-2018 A4R43_18190 af2eca86e0dffb0b742ed81ec674470b 298 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 99 266 1.5E-39 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_18190 af2eca86e0dffb0b742ed81ec674470b 298 SUPERFAMILY SSF51735 93 267 1.67E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 Pfam PF04324 BFD-like [2Fe-2S] binding domain 425 471 1.5E-11 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 300 6.5E-54 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 Gene3D G3DSA:3.50.50.60 116 243 1.0E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 8.6E-19 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 8.6E-19 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.6E-19 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 8.6E-19 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 8.6E-19 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 Gene3D G3DSA:3.50.50.60 5 300 1.0E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 SUPERFAMILY SSF51905 1 199 7.69E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 Gene3D G3DSA:1.10.10.1100 417 477 1.3E-8 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 8.2E-11 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 8.2E-11 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 8.2E-11 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 8.2E-11 T 14-10-2018 A4R43_35895 21ac6cdafe56723ce3d3511ad8753ae0 479 SUPERFAMILY SSF51905 153 309 5.18E-25 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07770 6f0340da52b3ca6e6efec9dc085e8e3a 340 Gene3D G3DSA:2.60.120.10 11 303 1.6E-98 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_07770 6f0340da52b3ca6e6efec9dc085e8e3a 340 Gene3D G3DSA:2.60.120.10 25 184 1.6E-98 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_07770 6f0340da52b3ca6e6efec9dc085e8e3a 340 Pfam PF07883 Cupin domain 222 272 2.1E-12 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_07770 6f0340da52b3ca6e6efec9dc085e8e3a 340 Pfam PF07883 Cupin domain 56 108 1.2E-6 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_07770 6f0340da52b3ca6e6efec9dc085e8e3a 340 SUPERFAMILY SSF51182 10 294 2.48E-30 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_13175 2e601e639021da6e2d7f23c47e0db80e 100 SUPERFAMILY SSF46689 1 39 1.1E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13175 2e601e639021da6e2d7f23c47e0db80e 100 Gene3D G3DSA:1.10.357.10 1 98 3.5E-26 T 14-10-2018 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 SUPERFAMILY SSF51905 1 304 7.13E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 4.8E-9 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 134 158 4.8E-9 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 296 4.8E-9 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 4.8E-9 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 8.8E-12 T 14-10-2018 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 268 8.8E-12 T 14-10-2018 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 8.8E-12 T 14-10-2018 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.8E-12 T 14-10-2018 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 274 1.3E-37 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_11755 e5aae3fd8c1e1fdd152f14a81109e8f8 370 Gene3D G3DSA:3.50.50.100 2 363 1.7E-72 T 14-10-2018 A4R43_23275 8599c5eb6bcdef6c3a45f196ecdba581 361 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 202 348 5.5E-7 T 14-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 A4R43_23275 8599c5eb6bcdef6c3a45f196ecdba581 361 SUPERFAMILY SSF53697 67 348 3.6E-48 T 14-10-2018 A4R43_21080 ebba400be36b5958b12ec6597ec9f7b0 157 Gene3D G3DSA:1.10.260.40 6 73 4.0E-11 T 14-10-2018 A4R43_21080 ebba400be36b5958b12ec6597ec9f7b0 157 SUPERFAMILY SSF47413 11 73 1.97E-7 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_21080 ebba400be36b5958b12ec6597ec9f7b0 157 Pfam PF13560 Helix-turn-helix domain 12 62 6.8E-7 T 14-10-2018 A4R43_04205 90140b2125e486f44c21f244f9bcb3ac 304 Gene3D G3DSA:3.20.20.70 11 304 6.8E-152 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_04205 90140b2125e486f44c21f244f9bcb3ac 304 SUPERFAMILY SSF51366 28 277 8.95E-61 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4R43_04205 90140b2125e486f44c21f244f9bcb3ac 304 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 14 304 52.974 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04205 90140b2125e486f44c21f244f9bcb3ac 304 ProSitePatterns PS01235 PdxS/SNZ family signature. 215 233 - T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04205 90140b2125e486f44c21f244f9bcb3ac 304 PIRSF PIRSF029271 5 304 4.7E-150 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04205 90140b2125e486f44c21f244f9bcb3ac 304 Pfam PF01680 SOR/SNZ family 17 222 6.9E-107 T 14-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04205 90140b2125e486f44c21f244f9bcb3ac 304 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 19 304 4.0E-144 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 3.9E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 SMART SM00448 3 117 4.2E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 SUPERFAMILY SSF46894 145 210 5.44E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 9.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 9.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 9.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 SUPERFAMILY SSF52172 2 131 6.83E-29 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 SMART SM00421 150 207 1.3E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 Gene3D G3DSA:3.40.50.12740 3 211 2.3E-60 T 14-10-2018 A4R43_27560 36a6c0a87a400b19f7d4cbe862cfe93c 215 Pfam PF00072 Response regulator receiver domain 5 117 1.2E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25060 7e2d21cc8ebec504f09728b3fc2ef4a8 206 Pfam PF03458 UPF0126 domain 5 78 2.3E-21 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 A4R43_25060 7e2d21cc8ebec504f09728b3fc2ef4a8 206 Pfam PF03458 UPF0126 domain 90 159 7.7E-18 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 A4R43_23605 90128032054dfd5e8f1850d99c11bec2 479 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 477 1.7E-236 T 14-10-2018 IPR005991 IMP dehydrogenase-related 1 A4R43_23605 90128032054dfd5e8f1850d99c11bec2 479 SUPERFAMILY SSF54631 94 203 2.02E-16 T 14-10-2018 A4R43_23605 90128032054dfd5e8f1850d99c11bec2 479 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 474 1.5E-102 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4R43_23605 90128032054dfd5e8f1850d99c11bec2 479 SUPERFAMILY SSF51412 11 473 2.75E-90 T 14-10-2018 A4R43_23605 90128032054dfd5e8f1850d99c11bec2 479 SMART SM01240 11 475 7.3E-187 T 14-10-2018 A4R43_23605 90128032054dfd5e8f1850d99c11bec2 479 Pfam PF00571 CBS domain 99 138 8.7E-5 T 14-10-2018 IPR000644 CBS domain A4R43_23605 90128032054dfd5e8f1850d99c11bec2 479 Gene3D G3DSA:3.20.20.70 5 476 2.1E-136 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_23605 90128032054dfd5e8f1850d99c11bec2 479 PIRSF PIRSF000130 4 479 4.6E-139 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A4R43_30450 84003af2c2581ad3e104d9a0f57fd2e8 228 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 188 1.4E-39 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4R43_30450 84003af2c2581ad3e104d9a0f57fd2e8 228 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 13 210 24.295 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4R43_30450 84003af2c2581ad3e104d9a0f57fd2e8 228 Gene3D G3DSA:3.40.50.150 11 227 3.6E-54 T 14-10-2018 A4R43_30450 84003af2c2581ad3e104d9a0f57fd2e8 228 SUPERFAMILY SSF53335 21 214 6.47E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_30450 84003af2c2581ad3e104d9a0f57fd2e8 228 Pfam PF02527 rRNA small subunit methyltransferase G 23 198 2.8E-49 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 Pfam PF03466 LysR substrate binding domain 87 287 1.0E-29 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 SUPERFAMILY SSF53850 88 286 1.71E-28 T 14-10-2018 A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 SUPERFAMILY SSF46785 2 84 6.19E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 Gene3D G3DSA:3.40.190.10 164 266 2.6E-25 T 14-10-2018 A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 Gene3D G3DSA:1.10.10.10 1 85 1.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37450 d96ed9b0aff692e637bacfef70345865 288 Gene3D G3DSA:3.40.190.10 93 285 2.6E-25 T 14-10-2018 A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.9E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.9E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.9E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 Gene3D G3DSA:1.10.10.10 5 54 2.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 SUPERFAMILY SSF46785 5 64 2.13E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 Pfam PF13404 AsnC-type helix-turn-helix domain 5 45 1.5E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 SMART SM00344 5 111 2.3E-29 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 SUPERFAMILY SSF54909 64 142 6.17E-13 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 Gene3D G3DSA:3.30.70.920 55 144 4.4E-17 T 14-10-2018 A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4R43_02545 a5d973f1dc15c654a5327d7cc8ccf86a 145 Pfam PF01037 Lrp/AsnC ligand binding domain 88 139 2.4E-12 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_02880 deed6ad93cf03b1263175a8a4003358f 468 Gene3D G3DSA:1.20.1250.20 4 203 8.8E-34 T 14-10-2018 A4R43_02880 deed6ad93cf03b1263175a8a4003358f 468 SUPERFAMILY SSF103473 7 464 7.5E-55 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_02880 deed6ad93cf03b1263175a8a4003358f 468 Gene3D G3DSA:1.20.1250.20 271 465 1.5E-13 T 14-10-2018 A4R43_02880 deed6ad93cf03b1263175a8a4003358f 468 Pfam PF07690 Major Facilitator Superfamily 19 412 1.6E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_16170 3a442c1be7ec350aad1b9f861ed64f58 122 Pfam PF05331 Protein of unknown function (DUF742) 9 122 7.4E-31 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_11995 5eec2de98dc46421a0d96cb95c0a4b41 313 Gene3D G3DSA:1.10.3720.10 58 306 3.0E-59 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_11995 5eec2de98dc46421a0d96cb95c0a4b41 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 301 1.0E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_11995 5eec2de98dc46421a0d96cb95c0a4b41 313 SUPERFAMILY SSF161098 10 306 1.59E-56 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_24910 e9e6d13c29badaa0b3879f86c4d855fe 182 Pfam PF02592 Putative vitamin uptake transporter 91 165 4.8E-11 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 A4R43_38835 0169e68130a983ca5e68ae98d79d2d53 229 Gene3D G3DSA:1.20.1260.10 62 228 1.3E-55 T 14-10-2018 IPR012347 Ferritin-like A4R43_38835 0169e68130a983ca5e68ae98d79d2d53 229 Pfam PF03713 Domain of unknown function (DUF305) 69 226 2.2E-49 T 14-10-2018 IPR005183 Domain of unknown function DUF305 A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 SMART SM00855 6 189 2.7E-23 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 Gene3D G3DSA:3.40.50.1240 2 243 1.0E-81 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 PIRSF PIRSF000709 138 214 0.16 T 14-10-2018 A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 PIRSF PIRSF000709 5 114 0.0012 T 14-10-2018 A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 6 247 1.6E-111 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 207 1.4E-31 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 SUPERFAMILY SSF53254 6 223 1.56E-70 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 4 230 42.662 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A4R43_32765 77abb90cd6299fad7bec53bb611f155c 247 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 A4R43_04600 c53481d6abde9480f1047c5703f0c42a 399 Pfam PF02720 Domain of unknown function (DUF222) 17 303 3.1E-12 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.3E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 SUPERFAMILY SSF51735 2 283 4.17E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 Gene3D G3DSA:3.40.50.720 2 295 2.4E-64 T 14-10-2018 A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 202 4.8E-4 T 14-10-2018 A4R43_19860 7dada3c7b5a660ff3ee1b837f09cac47 325 Pfam PF00106 short chain dehydrogenase 8 211 3.8E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_16900 5b389c8e2b5e555f96e25f19b4a759e5 224 SUPERFAMILY SSF52172 2 117 5.55E-31 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_16900 5b389c8e2b5e555f96e25f19b4a759e5 224 SMART SM00862 145 217 5.1E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_16900 5b389c8e2b5e555f96e25f19b4a759e5 224 SUPERFAMILY SSF46894 123 217 3.12E-24 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_16900 5b389c8e2b5e555f96e25f19b4a759e5 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 4.4E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_16900 5b389c8e2b5e555f96e25f19b4a759e5 224 Gene3D G3DSA:1.10.10.10 123 224 2.1E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_16900 5b389c8e2b5e555f96e25f19b4a759e5 224 Gene3D G3DSA:3.40.50.2300 1 119 3.7E-29 T 14-10-2018 A4R43_16900 5b389c8e2b5e555f96e25f19b4a759e5 224 SMART SM00448 1 109 1.3E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_16900 5b389c8e2b5e555f96e25f19b4a759e5 224 Pfam PF00072 Response regulator receiver domain 3 109 1.7E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 Gene3D G3DSA:3.40.50.300 375 567 2.9E-70 T 14-10-2018 A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 SMART SM00490 474 553 8.6E-20 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 SMART SM00487 179 339 2.2E-25 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 Gene3D G3DSA:3.40.50.10810 175 252 2.0E-25 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 Pfam PF00176 SNF2 family N-terminal domain 200 251 7.8E-14 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 Gene3D G3DSA:3.40.50.10810 253 366 1.2E-33 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 SUPERFAMILY SSF52540 369 608 8.06E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 SUPERFAMILY SSF52540 180 367 1.31E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 Pfam PF00271 Helicase conserved C-terminal domain 445 553 5.0E-14 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 Pfam PF00176 SNF2 family N-terminal domain 254 432 1.2E-34 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4R43_08795 21d3413f506510d12e1d19a363c126ae 616 Gene3D G3DSA:1.20.120.850 389 592 2.9E-70 T 14-10-2018 A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 SUPERFAMILY SSF52374 10 179 5.91E-31 T 14-10-2018 A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 PIRSF PIRSF004491 4 315 7.5E-93 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 Pfam PF06574 FAD synthetase 9 145 1.2E-50 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 SUPERFAMILY SSF82114 178 314 4.58E-39 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 12 313 1.4E-69 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 Gene3D G3DSA:2.40.30.30 190 315 4.9E-41 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 Gene3D G3DSA:3.40.50.620 1 189 5.9E-59 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 Pfam PF01687 Riboflavin kinase 188 313 6.2E-33 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 A4R43_41135 e6125283e6903d3135c6a5af4ede062f 315 SMART SM00904 187 314 2.1E-51 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 A4R43_39685 ec5ef576d042e7911f87ba1316b3bed8 117 Pfam PF04505 Interferon-induced transmembrane protein 28 95 1.1E-21 T 14-10-2018 IPR007593 CD225/Dispanin family GO:0016021 A4R43_33675 381f48516ebbd79e321504ea297c3a43 301 SMART SM00382 28 206 2.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_33675 381f48516ebbd79e321504ea297c3a43 301 Gene3D G3DSA:3.40.50.300 1 228 1.3E-64 T 14-10-2018 A4R43_33675 381f48516ebbd79e321504ea297c3a43 301 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_33675 381f48516ebbd79e321504ea297c3a43 301 Pfam PF00005 ABC transporter 20 157 9.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_33675 381f48516ebbd79e321504ea297c3a43 301 SUPERFAMILY SSF52540 3 226 2.97E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25245 45018335b8fcf795011a8b95a2ff2f24 401 SUPERFAMILY SSF47413 3 63 4.79E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_25245 45018335b8fcf795011a8b95a2ff2f24 401 Gene3D G3DSA:1.10.260.40 1 91 1.2E-12 T 14-10-2018 A4R43_25245 45018335b8fcf795011a8b95a2ff2f24 401 SUPERFAMILY SSF48452 290 370 2.78E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_25245 45018335b8fcf795011a8b95a2ff2f24 401 Gene3D G3DSA:1.25.40.10 124 398 6.3E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_25245 45018335b8fcf795011a8b95a2ff2f24 401 Pfam PF13560 Helix-turn-helix domain 4 65 3.5E-13 T 14-10-2018 A4R43_25245 45018335b8fcf795011a8b95a2ff2f24 401 SMART SM00530 7 62 2.3E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_13170 7db88a7283e7bb2ed73be0c4c4c46862 421 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 3 141 1.3E-36 T 14-10-2018 IPR009827 Dicarboxylate carrier MatC N-terminal A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00385 P450 superfamily signature 348 359 1.6E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00385 P450 superfamily signature 237 254 1.6E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00385 P450 superfamily signature 272 283 1.6E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00385 P450 superfamily signature 339 348 1.6E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 Pfam PF00067 Cytochrome P450 180 367 9.9E-26 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 Gene3D G3DSA:1.10.630.10 4 399 2.4E-124 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 137 153 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 154 169 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 348 359 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 339 348 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 318 333 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 90 101 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 191 213 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 272 283 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 PRINTS PR00359 B-class P450 signature 290 317 1.7E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 SUPERFAMILY SSF48264 8 399 9.56E-96 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37630 6040849a7a36a90711574f20c2ea8dd8 399 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_07220 410b31ffe13375a2f42edf7c6af934cf 255 Gene3D G3DSA:1.10.10.60 142 243 5.9E-16 T 14-10-2018 A4R43_07220 410b31ffe13375a2f42edf7c6af934cf 255 Pfam PF12833 Helix-turn-helix domain 158 236 2.6E-13 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_07220 410b31ffe13375a2f42edf7c6af934cf 255 SMART SM00342 151 237 5.8E-8 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03765 5b33923dbe7563fbce6ae5ea6df7dcf4 300 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 10 254 6.4E-58 T 14-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 A4R43_03765 5b33923dbe7563fbce6ae5ea6df7dcf4 300 SUPERFAMILY SSF53850 33 257 6.26E-35 T 14-10-2018 A4R43_03765 5b33923dbe7563fbce6ae5ea6df7dcf4 300 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 40 261 2.2E-53 T 14-10-2018 A4R43_03765 5b33923dbe7563fbce6ae5ea6df7dcf4 300 Gene3D G3DSA:3.40.190.10 40 255 1.6E-54 T 14-10-2018 A4R43_03765 5b33923dbe7563fbce6ae5ea6df7dcf4 300 Gene3D G3DSA:3.40.190.10 124 230 1.6E-54 T 14-10-2018 A4R43_38385 42e722c3d45a740a04f88f6a940062ee 389 PRINTS PR01035 Tetracycline resistance protein signature 133 155 3.1E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_38385 42e722c3d45a740a04f88f6a940062ee 389 PRINTS PR01035 Tetracycline resistance protein signature 40 59 3.1E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_38385 42e722c3d45a740a04f88f6a940062ee 389 PRINTS PR01035 Tetracycline resistance protein signature 290 310 3.1E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_38385 42e722c3d45a740a04f88f6a940062ee 389 PRINTS PR01035 Tetracycline resistance protein signature 10 26 3.1E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_38385 42e722c3d45a740a04f88f6a940062ee 389 Gene3D G3DSA:1.20.1250.20 3 374 1.9E-47 T 14-10-2018 A4R43_38385 42e722c3d45a740a04f88f6a940062ee 389 Pfam PF07690 Major Facilitator Superfamily 8 329 1.3E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_38385 42e722c3d45a740a04f88f6a940062ee 389 SUPERFAMILY SSF103473 3 380 3.01E-57 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_11355 357dd05156185d52cdd8403750913580 467 SUPERFAMILY SSF53383 5 388 5.56E-86 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_11355 357dd05156185d52cdd8403750913580 467 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 37 311 1.1E-19 T 14-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A4R43_11355 357dd05156185d52cdd8403750913580 467 Gene3D G3DSA:3.90.1150.10 4 380 3.3E-91 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_11355 357dd05156185d52cdd8403750913580 467 Gene3D G3DSA:3.40.640.10 39 287 3.3E-91 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_16145 10ddef4482501bccd2497f3538fcf32e 276 Pfam PF00296 Luciferase-like monooxygenase 21 222 6.4E-50 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_16145 10ddef4482501bccd2497f3538fcf32e 276 Gene3D G3DSA:3.20.20.30 6 271 3.5E-68 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_16145 10ddef4482501bccd2497f3538fcf32e 276 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 19 251 1.3E-82 T 14-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted A4R43_16145 10ddef4482501bccd2497f3538fcf32e 276 SUPERFAMILY SSF51679 19 270 3.4E-59 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_37030 60e0943b07ce2285a51b1a7a760aec6b 471 SUPERFAMILY SSF55469 368 460 7.38E-7 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_37030 60e0943b07ce2285a51b1a7a760aec6b 471 Gene3D G3DSA:3.40.109.10 217 467 1.3E-36 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_37030 60e0943b07ce2285a51b1a7a760aec6b 471 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 295 468 2.8E-31 T 14-10-2018 IPR020051 SagB-type dehydrogenase domain A4R43_37765 26defc362a9ab208fde136c539badb18 247 SUPERFAMILY SSF51735 3 245 1.64E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37765 26defc362a9ab208fde136c539badb18 247 Gene3D G3DSA:3.40.50.720 2 245 7.4E-44 T 14-10-2018 A4R43_37765 26defc362a9ab208fde136c539badb18 247 Pfam PF00106 short chain dehydrogenase 4 192 1.7E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37765 26defc362a9ab208fde136c539badb18 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 193 2.8E-4 T 14-10-2018 A4R43_37765 26defc362a9ab208fde136c539badb18 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37765 26defc362a9ab208fde136c539badb18 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37765 26defc362a9ab208fde136c539badb18 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37765 26defc362a9ab208fde136c539badb18 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37765 26defc362a9ab208fde136c539badb18 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37765 26defc362a9ab208fde136c539badb18 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_15370 a908b756d50580cd658b99c9a04a188e 510 SMART SM00220 9 270 1.6E-52 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_15370 a908b756d50580cd658b99c9a04a188e 510 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 38 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_15370 a908b756d50580cd658b99c9a04a188e 510 Gene3D G3DSA:1.10.510.10 91 275 1.9E-44 T 14-10-2018 A4R43_15370 a908b756d50580cd658b99c9a04a188e 510 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_15370 a908b756d50580cd658b99c9a04a188e 510 Gene3D G3DSA:3.30.200.20 7 88 3.2E-28 T 14-10-2018 A4R43_15370 a908b756d50580cd658b99c9a04a188e 510 SUPERFAMILY SSF56112 6 346 1.07E-67 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_15370 a908b756d50580cd658b99c9a04a188e 510 Pfam PF00069 Protein kinase domain 9 258 2.3E-41 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_14200 ab373323bd63bcdb166b885b0baa2441 207 SUPERFAMILY SSF55811 9 179 1.08E-39 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_14200 ab373323bd63bcdb166b885b0baa2441 207 Gene3D G3DSA:3.90.79.10 5 207 7.3E-59 T 14-10-2018 A4R43_14200 ab373323bd63bcdb166b885b0baa2441 207 Pfam PF00293 NUDIX domain 48 158 2.1E-13 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 SUPERFAMILY SSF53067 1 168 1.88E-44 T 14-10-2018 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 PIRSF PIRSF000722 33 361 8.3E-95 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 PIRSF PIRSF000722 1 44 0.095 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 PRINTS PR00471 Acetate kinase family signature 145 158 1.6E-28 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 PRINTS PR00471 Acetate kinase family signature 3 14 1.6E-28 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 PRINTS PR00471 Acetate kinase family signature 268 281 1.6E-28 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 PRINTS PR00471 Acetate kinase family signature 175 196 1.6E-28 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 PRINTS PR00471 Acetate kinase family signature 290 306 1.6E-28 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 PRINTS PR00471 Acetate kinase family signature 340 352 1.6E-28 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 Pfam PF00871 Acetokinase family 55 351 2.1E-86 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 Gene3D G3DSA:3.30.420.40 168 361 1.0E-54 T 14-10-2018 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 Hamap MF_00020 Acetate kinase [ackA]. 1 361 111.21 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 TIGRFAM TIGR00016 ackA: acetate kinase 55 358 1.4E-88 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 SUPERFAMILY SSF53067 129 358 7.23E-62 T 14-10-2018 A4R43_15585 1b81e74028cc2045560f613bca1d626c 361 Gene3D G3DSA:3.30.420.40 1 167 1.2E-46 T 14-10-2018 A4R43_40660 666f00eddb494814d93fb20eae8af5d9 312 Gene3D G3DSA:3.90.920.30 23 302 4.4E-88 T 14-10-2018 A4R43_40660 666f00eddb494814d93fb20eae8af5d9 312 Pfam PF01896 DNA primase small subunit 138 259 1.5E-6 T 14-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A4R43_40660 666f00eddb494814d93fb20eae8af5d9 312 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 16 263 3.4E-69 T 14-10-2018 IPR014145 DNA ligase D, polymerase domain A4R43_19510 11c62f352fef940988123e67c24b03af 158 Pfam PF00583 Acetyltransferase (GNAT) family 30 134 2.0E-11 T 14-10-2018 IPR000182 GNAT domain A4R43_19510 11c62f352fef940988123e67c24b03af 158 Gene3D G3DSA:3.40.630.30 1 157 1.8E-31 T 14-10-2018 A4R43_19510 11c62f352fef940988123e67c24b03af 158 SUPERFAMILY SSF55729 5 144 9.09E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_30340 f74c15041ee5323bfce6f107b77f56f7 92 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 72 3.6E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_39080 4b23cace0a253e346d8bea87a825f6ee 452 SUPERFAMILY SSF103473 13 434 1.7E-46 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_39080 4b23cace0a253e346d8bea87a825f6ee 452 Pfam PF07690 Major Facilitator Superfamily 34 389 4.5E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_39080 4b23cace0a253e346d8bea87a825f6ee 452 Gene3D G3DSA:1.20.1250.20 16 432 1.3E-37 T 14-10-2018 A4R43_34595 74045abd7654ef81488641c82c6d5f43 407 Gene3D G3DSA:3.40.718.10 1 406 1.3E-216 T 14-10-2018 A4R43_34595 74045abd7654ef81488641c82c6d5f43 407 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 271 290 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4R43_34595 74045abd7654ef81488641c82c6d5f43 407 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 392 6.8E-72 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_34595 74045abd7654ef81488641c82c6d5f43 407 SMART SM01329 9 396 2.2E-134 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_34595 74045abd7654ef81488641c82c6d5f43 407 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 405 1.9E-212 T 14-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A4R43_34595 74045abd7654ef81488641c82c6d5f43 407 PIRSF PIRSF000108 1 407 5.1E-223 T 14-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A4R43_34595 74045abd7654ef81488641c82c6d5f43 407 SUPERFAMILY SSF53659 1 404 7.87E-153 T 14-10-2018 A4R43_10615 148ae9efadda78dc876e9e004bc653c9 125 Gene3D G3DSA:3.10.180.10 1 118 2.2E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_10615 148ae9efadda78dc876e9e004bc653c9 125 SUPERFAMILY SSF54593 11 117 9.11E-9 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_22315 d341d6e07950874f4e4fc8e6fff9d001 208 Pfam PF01810 LysE type translocator 15 206 6.9E-39 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_22315 d341d6e07950874f4e4fc8e6fff9d001 208 PIRSF PIRSF006324 1 208 4.3E-57 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_11235 5c2fe6a5ab15274904aa74bb81304985 188 Gene3D G3DSA:1.10.1660.10 30 102 3.3E-13 T 14-10-2018 A4R43_11235 5c2fe6a5ab15274904aa74bb81304985 188 SMART SM00422 30 102 5.0E-19 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_11235 5c2fe6a5ab15274904aa74bb81304985 188 SUPERFAMILY SSF46955 33 115 3.2E-14 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_11235 5c2fe6a5ab15274904aa74bb81304985 188 Pfam PF13411 MerR HTH family regulatory protein 33 99 7.9E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_41115 71e9d348d3fec3ee9d67828399e77ba4 65 Pfam PF04149 Domain of unknown function (DUF397) 10 62 4.0E-22 T 14-10-2018 IPR007278 Domain of unknown function DUF397 A4R43_39550 4051b0507ef5b8bba4a36566e6b4f4a4 245 Gene3D G3DSA:3.40.50.150 4 232 7.4E-34 T 14-10-2018 A4R43_39550 4051b0507ef5b8bba4a36566e6b4f4a4 245 Pfam PF08241 Methyltransferase domain 38 129 4.2E-20 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_39550 4051b0507ef5b8bba4a36566e6b4f4a4 245 SUPERFAMILY SSF53335 17 245 3.16E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_20195 437147f99f5cdf3162574b8e8c0e89fa 139 Gene3D G3DSA:2.30.110.10 3 138 1.1E-23 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_20195 437147f99f5cdf3162574b8e8c0e89fa 139 SUPERFAMILY SSF50475 7 132 3.21E-13 T 14-10-2018 A4R43_20195 437147f99f5cdf3162574b8e8c0e89fa 139 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 11 133 8.8E-17 T 14-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4R43_32235 8d7a092e1dfe9d335fa32c312d4cf0b0 333 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 10 254 1.6E-18 T 14-10-2018 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 A4R43_32235 8d7a092e1dfe9d335fa32c312d4cf0b0 333 SUPERFAMILY SSF51735 6 317 6.81E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_32235 8d7a092e1dfe9d335fa32c312d4cf0b0 333 Gene3D G3DSA:3.40.50.720 3 319 2.3E-54 T 14-10-2018 A4R43_40460 734f61243328bc24dbc906938f015864 352 Gene3D G3DSA:3.30.565.10 228 351 3.2E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_40460 734f61243328bc24dbc906938f015864 352 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 266 350 6.7E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_40460 734f61243328bc24dbc906938f015864 352 SUPERFAMILY SSF55874 245 350 1.37E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_38255 07e2ec067b82a9def200f5244c90951f 292 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 242 1.9E-10 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_38255 07e2ec067b82a9def200f5244c90951f 292 PRINTS PR00723 Subtilisin serine protease family (S8) signature 39 58 1.9E-10 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_38255 07e2ec067b82a9def200f5244c90951f 292 PRINTS PR00723 Subtilisin serine protease family (S8) signature 76 89 1.9E-10 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_38255 07e2ec067b82a9def200f5244c90951f 292 Pfam PF00082 Subtilase family 46 264 1.4E-19 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_38255 07e2ec067b82a9def200f5244c90951f 292 SUPERFAMILY SSF52743 17 271 9.03E-58 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_38255 07e2ec067b82a9def200f5244c90951f 292 Gene3D G3DSA:3.40.50.200 12 285 4.6E-72 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_16455 6da5d1012451880c8935e649916c52c3 443 Gene3D G3DSA:3.40.640.10 50 303 2.0E-96 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_16455 6da5d1012451880c8935e649916c52c3 443 SUPERFAMILY SSF53383 30 415 6.99E-81 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_16455 6da5d1012451880c8935e649916c52c3 443 Gene3D G3DSA:3.90.1150.10 30 407 2.0E-96 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_16455 6da5d1012451880c8935e649916c52c3 443 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A4R43_16455 6da5d1012451880c8935e649916c52c3 443 Pfam PF00266 Aminotransferase class-V 33 406 4.1E-75 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_10210 dd042bfb761a1b060579e534a9c11422 441 Pfam PF01566 Natural resistance-associated macrophage protein 42 302 8.1E-23 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 Gene3D G3DSA:3.40.50.10090 270 410 7.7E-31 T 14-10-2018 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 Gene3D G3DSA:3.40.1010.10 1 117 2.9E-22 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 Pfam PF02602 Uroporphyrinogen-III synthase HemD 252 482 7.8E-65 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 SUPERFAMILY SSF69618 238 489 3.66E-69 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 203 6.0E-36 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 Gene3D G3DSA:3.30.950.10 119 254 2.0E-22 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 Gene3D G3DSA:3.40.50.10090 418 504 1.3E-10 T 14-10-2018 A4R43_32930 95a3c787f2fed697b64ca43a0046fef2 510 SUPERFAMILY SSF53790 5 241 1.28E-43 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4R43_16990 c6a0263298a7a204eeab3ed03918aacb 351 Gene3D G3DSA:3.40.630.30 196 351 2.2E-28 T 14-10-2018 A4R43_16990 c6a0263298a7a204eeab3ed03918aacb 351 Gene3D G3DSA:3.30.70.260 17 94 2.9E-6 T 14-10-2018 A4R43_16990 c6a0263298a7a204eeab3ed03918aacb 351 SUPERFAMILY SSF55021 18 83 9.54E-8 T 14-10-2018 A4R43_16990 c6a0263298a7a204eeab3ed03918aacb 351 SUPERFAMILY SSF55729 206 337 2.42E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_16990 c6a0263298a7a204eeab3ed03918aacb 351 Pfam PF01842 ACT domain 20 76 6.4E-7 T 14-10-2018 IPR002912 ACT domain A4R43_36570 627b3413b4e580034b72dbfbb7d4ffb4 276 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 22 134 4.9E-32 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_36570 627b3413b4e580034b72dbfbb7d4ffb4 276 Gene3D G3DSA:2.30.110.10 1 135 2.5E-51 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_36570 627b3413b4e580034b72dbfbb7d4ffb4 276 SUPERFAMILY SSF50475 23 136 4.12E-10 T 14-10-2018 A4R43_36570 627b3413b4e580034b72dbfbb7d4ffb4 276 Pfam PF04075 F420H(2)-dependent quinone reductase 12 134 1.3E-34 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_36570 627b3413b4e580034b72dbfbb7d4ffb4 276 Gene3D G3DSA:1.20.120.520 136 276 5.8E-24 T 14-10-2018 A4R43_36570 627b3413b4e580034b72dbfbb7d4ffb4 276 Pfam PF01814 Hemerythrin HHE cation binding domain 148 273 1.1E-20 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 SUPERFAMILY SSF52540 371 531 4.73E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 Gene3D G3DSA:3.40.50.300 353 533 5.1E-31 T 14-10-2018 A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 Pfam PF00005 ABC transporter 26 193 1.0E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 Pfam PF00005 ABC transporter 370 486 9.4E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 Pfam PF12848 ABC transporter 242 303 2.3E-6 T 14-10-2018 IPR032781 ABC-transporter extension domain A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 Gene3D G3DSA:3.40.50.300 7 289 2.2E-61 T 14-10-2018 A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 SUPERFAMILY SSF52540 10 234 7.45E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 SMART SM00382 375 533 6.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 SMART SM00382 34 237 2.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10950 eba34a7032cda5bf5ffcd2bf4a0e09b8 535 ProSitePatterns PS00211 ABC transporters family signature. 458 472 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_22480 fd681a47e0ee8d197949e38586abc468 253 Pfam PF03713 Domain of unknown function (DUF305) 75 242 5.8E-45 T 14-10-2018 IPR005183 Domain of unknown function DUF305 A4R43_22480 fd681a47e0ee8d197949e38586abc468 253 Gene3D G3DSA:1.20.1260.10 68 246 6.7E-58 T 14-10-2018 IPR012347 Ferritin-like A4R43_26055 ed81423388f2f53680cd39a668d7b4df 264 Gene3D G3DSA:3.40.190.10 34 253 1.8E-80 T 14-10-2018 A4R43_26055 ed81423388f2f53680cd39a668d7b4df 264 Gene3D G3DSA:3.40.190.10 129 220 1.8E-80 T 14-10-2018 A4R43_26055 ed81423388f2f53680cd39a668d7b4df 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 264 5.3E-43 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_26055 ed81423388f2f53680cd39a668d7b4df 264 SUPERFAMILY SSF53850 9 264 7.15E-50 T 14-10-2018 A4R43_26055 ed81423388f2f53680cd39a668d7b4df 264 SMART SM00062 42 264 3.2E-43 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_12730 ee92a048d2d9ba0fc1dc270fdab1aad5 425 Gene3D G3DSA:3.40.630.10 29 420 3.4E-139 T 14-10-2018 A4R43_12730 ee92a048d2d9ba0fc1dc270fdab1aad5 425 SUPERFAMILY SSF55031 207 320 3.29E-14 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_12730 ee92a048d2d9ba0fc1dc270fdab1aad5 425 Gene3D G3DSA:3.30.70.360 207 332 3.4E-139 T 14-10-2018 A4R43_12730 ee92a048d2d9ba0fc1dc270fdab1aad5 425 Pfam PF01546 Peptidase family M20/M25/M40 100 414 7.0E-29 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_12730 ee92a048d2d9ba0fc1dc270fdab1aad5 425 Pfam PF07687 Peptidase dimerisation domain 204 316 1.8E-15 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_12730 ee92a048d2d9ba0fc1dc270fdab1aad5 425 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 24 408 3.3E-82 T 14-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A4R43_12730 ee92a048d2d9ba0fc1dc270fdab1aad5 425 SUPERFAMILY SSF53187 9 420 8.86E-54 T 14-10-2018 A4R43_24040 0b66e7b2f5ef0ae9d8c39d371d89d9ac 197 Pfam PF01195 Peptidyl-tRNA hydrolase 14 194 5.6E-52 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4R43_24040 0b66e7b2f5ef0ae9d8c39d371d89d9ac 197 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 13 195 1.1E-53 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4R43_24040 0b66e7b2f5ef0ae9d8c39d371d89d9ac 197 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 117 127 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A4R43_24040 0b66e7b2f5ef0ae9d8c39d371d89d9ac 197 Gene3D G3DSA:3.40.50.1470 9 197 1.0E-66 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 A4R43_24040 0b66e7b2f5ef0ae9d8c39d371d89d9ac 197 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 24 37 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A4R43_24040 0b66e7b2f5ef0ae9d8c39d371d89d9ac 197 SUPERFAMILY SSF53178 12 195 2.75E-63 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 A4R43_24040 0b66e7b2f5ef0ae9d8c39d371d89d9ac 197 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 11 188 33.33 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4R43_14675 96574a1d628c884a824bff3fe6a14011 351 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 311 2.8E-117 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 A4R43_14675 96574a1d628c884a824bff3fe6a14011 351 Pfam PF03741 Integral membrane protein TerC family 69 272 7.5E-51 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A4R43_27025 f64e60191a4a91ac7210accf18195cc5 384 Gene3D G3DSA:3.30.450.380 6 149 1.8E-21 T 14-10-2018 A4R43_27025 f64e60191a4a91ac7210accf18195cc5 384 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 345 8.3E-145 T 14-10-2018 IPR022399 Helicase/secretion neighbourhood ATPase A4R43_27025 f64e60191a4a91ac7210accf18195cc5 384 Gene3D G3DSA:3.40.50.300 150 351 3.1E-55 T 14-10-2018 A4R43_27025 f64e60191a4a91ac7210accf18195cc5 384 Pfam PF00437 Type II/IV secretion system protein 55 332 1.4E-70 T 14-10-2018 IPR001482 Type II/IV secretion system protein A4R43_27025 f64e60191a4a91ac7210accf18195cc5 384 SUPERFAMILY SSF52540 40 338 3.03E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31940 0f169d34d6cfa10cc414d3765c846d92 145 SUPERFAMILY SSF75620 14 104 3.65E-9 T 14-10-2018 A4R43_31940 0f169d34d6cfa10cc414d3765c846d92 145 Gene3D G3DSA:3.30.160.20 8 144 5.4E-34 T 14-10-2018 A4R43_31940 0f169d34d6cfa10cc414d3765c846d92 145 Pfam PF00472 RF-1 domain 14 139 1.7E-21 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4R43_15735 79db2f6aca896aeb1276a4f1d210b14b 396 Pfam PF07730 Histidine kinase 192 257 4.2E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_15735 79db2f6aca896aeb1276a4f1d210b14b 396 SUPERFAMILY SSF55874 287 387 1.3E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_15735 79db2f6aca896aeb1276a4f1d210b14b 396 Gene3D G3DSA:3.30.565.10 270 391 5.9E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_15875 5200a9e7492b5141d623d0a8f7283bc4 404 PIRSF PIRSF006060 1 398 4.9E-63 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_15875 5200a9e7492b5141d623d0a8f7283bc4 404 Pfam PF13520 Amino acid permease 9 354 1.5E-45 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_15875 5200a9e7492b5141d623d0a8f7283bc4 404 Gene3D G3DSA:1.20.1740.10 3 404 1.8E-80 T 14-10-2018 A4R43_26160 e161df81d4c294dfabd836c6e9788866 267 Pfam PF00520 Ion transport protein 14 223 9.5E-44 T 14-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 A4R43_26160 e161df81d4c294dfabd836c6e9788866 267 Gene3D G3DSA:1.20.120.350 3 115 8.9E-30 T 14-10-2018 IPR027359 Voltage-dependent channel domain superfamily A4R43_26160 e161df81d4c294dfabd836c6e9788866 267 Gene3D G3DSA:1.10.287.70 116 226 1.3E-31 T 14-10-2018 A4R43_26160 e161df81d4c294dfabd836c6e9788866 267 SUPERFAMILY SSF81324 12 222 6.28E-35 T 14-10-2018 A4R43_41040 1982e0180f0c2fcb85cbac307d9d005d 315 SUPERFAMILY SSF47240 173 313 2.3E-35 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_41040 1982e0180f0c2fcb85cbac307d9d005d 315 Pfam PF14530 Domain of unknown function (DUF4439) 180 314 7.2E-39 T 14-10-2018 IPR029447 Domain of unknown function DUF4439 A4R43_41040 1982e0180f0c2fcb85cbac307d9d005d 315 Gene3D G3DSA:1.20.1260.10 174 305 5.3E-41 T 14-10-2018 IPR012347 Ferritin-like A4R43_39000 63372c1798d36e736ce5ef2e789cbe7b 480 SUPERFAMILY SSF52540 35 168 8.64E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39000 63372c1798d36e736ce5ef2e789cbe7b 480 Pfam PF00350 Dynamin family 40 65 7.5E-5 T 14-10-2018 IPR022812 Dynamin superfamily A4R43_25590 ad7f8386b0e44287174e3d1cbe642a50 555 Gene3D G3DSA:1.10.4160.10 28 467 2.4E-20 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 SUPERFAMILY SSF48264 33 466 3.93E-114 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 406 415 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00385 P450 superfamily signature 277 294 2.5E-11 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00385 P450 superfamily signature 413 424 2.5E-11 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00385 P450 superfamily signature 404 413 2.5E-11 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00385 P450 superfamily signature 329 340 2.5E-11 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 Pfam PF00067 Cytochrome P450 43 457 1.2E-88 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 Gene3D G3DSA:1.10.630.10 27 466 3.2E-123 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00463 E-class P450 group I signature 286 312 3.5E-27 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00463 E-class P450 group I signature 403 413 3.5E-27 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00463 E-class P450 group I signature 49 68 3.5E-27 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00463 E-class P450 group I signature 413 436 3.5E-27 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00463 E-class P450 group I signature 368 392 3.5E-27 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_09320 9e04e4b0eb71a896260eff9688d554d2 466 PRINTS PR00463 E-class P450 group I signature 266 283 3.5E-27 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Gene3D G3DSA:3.40.50.1380 958 1101 3.3E-40 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 SUPERFAMILY SSF56059 128 400 5.83E-103 T 14-10-2018 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 SMART SM01096 422 545 2.7E-59 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 545 1.5E-36 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 SUPERFAMILY SSF56059 680 954 4.24E-91 T 14-10-2018 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 SUPERFAMILY SSF52440 1 127 3.31E-46 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 SUPERFAMILY SSF48108 396 548 1.7E-41 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1077 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Gene3D G3DSA:3.30.470.20 672 957 2.5E-101 T 14-10-2018 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 SMART SM00851 977 1068 4.1E-28 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Gene3D G3DSA:3.30.470.20 120 401 1.9E-119 T 14-10-2018 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 4.7E-67 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 882 2.3E-30 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Gene3D G3DSA:1.10.1030.10 402 551 5.8E-38 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1089 12.915 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 845 852 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Pfam PF02142 MGS-like domain 978 1068 3.8E-20 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 9.3E-61 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 9.3E-61 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 9.3E-61 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 9.3E-61 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 9.3E-61 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 9.3E-61 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 9.3E-61 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 SUPERFAMILY SSF52440 560 681 4.75E-44 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 716 730 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Gene3D G3DSA:3.40.50.20 556 669 2.3E-46 T 14-10-2018 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 Gene3D G3DSA:3.40.50.20 1 116 2.6E-47 T 14-10-2018 A4R43_04735 b9b524f693d9e9413c44e2475bf04b81 1104 SUPERFAMILY SSF52335 963 1097 2.22E-34 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A4R43_22160 891c4ffa41d3a5af44723ce3563fcb50 320 Gene3D G3DSA:3.40.50.880 3 211 3.1E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_22160 891c4ffa41d3a5af44723ce3563fcb50 320 SMART SM00342 231 314 1.3E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_22160 891c4ffa41d3a5af44723ce3563fcb50 320 SUPERFAMILY SSF52317 4 197 2.38E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_22160 891c4ffa41d3a5af44723ce3563fcb50 320 SUPERFAMILY SSF46689 220 265 1.04E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22160 891c4ffa41d3a5af44723ce3563fcb50 320 Gene3D G3DSA:1.10.10.60 217 319 2.8E-22 T 14-10-2018 A4R43_22160 891c4ffa41d3a5af44723ce3563fcb50 320 SUPERFAMILY SSF46689 268 317 2.22E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22160 891c4ffa41d3a5af44723ce3563fcb50 320 Pfam PF12833 Helix-turn-helix domain 237 315 1.0E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_22160 891c4ffa41d3a5af44723ce3563fcb50 320 Pfam PF01965 DJ-1/PfpI family 5 176 5.0E-21 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_14710 b131d2647127e79efe6c7abae2300f31 77 Gene3D G3DSA:3.30.2170.10 1 59 4.6E-12 T 14-10-2018 A4R43_14710 b131d2647127e79efe6c7abae2300f31 77 Pfam PF04493 Endonuclease V 1 49 5.8E-11 T 14-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A4R43_19530 8202eeb0851b3df5fb50e2a05e342b8b 322 SMART SM00710 269 293 1600.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_19530 8202eeb0851b3df5fb50e2a05e342b8b 322 SMART SM00710 95 116 7500.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_19530 8202eeb0851b3df5fb50e2a05e342b8b 322 SMART SM00710 141 169 37.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_19530 8202eeb0851b3df5fb50e2a05e342b8b 322 SMART SM00710 117 139 2100.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_19530 8202eeb0851b3df5fb50e2a05e342b8b 322 SMART SM00710 207 243 1000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_19530 8202eeb0851b3df5fb50e2a05e342b8b 322 Pfam PF13229 Right handed beta helix region 87 244 2.7E-8 T 14-10-2018 IPR039448 Right handed beta helix domain A4R43_19530 8202eeb0851b3df5fb50e2a05e342b8b 322 SUPERFAMILY SSF51126 14 315 2.51E-34 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_19530 8202eeb0851b3df5fb50e2a05e342b8b 322 Gene3D G3DSA:2.160.20.10 20 321 6.8E-33 T 14-10-2018 IPR012334 Pectin lyase fold A4R43_33260 db7a6e094103f38e4661c9fa4362fe2f 686 SUPERFAMILY SSF53448 4 236 3.75E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_33260 db7a6e094103f38e4661c9fa4362fe2f 686 Pfam PF13692 Glycosyl transferases group 1 520 649 2.5E-9 T 14-10-2018 A4R43_33260 db7a6e094103f38e4661c9fa4362fe2f 686 Gene3D G3DSA:3.90.550.10 1 237 2.8E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_33260 db7a6e094103f38e4661c9fa4362fe2f 686 SUPERFAMILY SSF53756 363 680 4.97E-20 T 14-10-2018 A4R43_33260 db7a6e094103f38e4661c9fa4362fe2f 686 Gene3D G3DSA:3.40.50.2000 507 654 1.4E-30 T 14-10-2018 A4R43_33260 db7a6e094103f38e4661c9fa4362fe2f 686 Pfam PF00535 Glycosyl transferase family 2 7 126 5.1E-18 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_37105 464e5d8c10c34819841c318c4a74390b 345 SUPERFAMILY SSF69118 16 178 3.4E-28 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_37105 464e5d8c10c34819841c318c4a74390b 345 Pfam PF02627 Carboxymuconolactone decarboxylase family 60 139 1.7E-7 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_37105 464e5d8c10c34819841c318c4a74390b 345 Gene3D G3DSA:1.20.1290.10 31 174 2.5E-14 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_14010 bd5245f0363b3509b7c482b27013f49d 675 Pfam PF13520 Amino acid permease 51 464 1.2E-25 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_14010 bd5245f0363b3509b7c482b27013f49d 675 Gene3D G3DSA:1.20.1740.10 49 506 1.9E-17 T 14-10-2018 A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 SMART SM00382 340 509 1.2E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 17 505 3.8E-154 T 14-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 Pfam PF00005 ABC transporter 331 463 4.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 SUPERFAMILY SSF90123 3 295 9.03E-38 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 Pfam PF00664 ABC transporter transmembrane region 49 267 3.2E-16 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 SUPERFAMILY SSF52540 308 512 5.01E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 Gene3D G3DSA:1.20.1560.10 6 302 8.3E-31 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 ProSitePatterns PS00211 ABC transporters family signature. 434 448 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_35580 6ed056290924b3f1d0db508d389894c3 516 Gene3D G3DSA:3.40.50.300 303 515 1.0E-63 T 14-10-2018 A4R43_40425 c6fbd08d1edf17086a311eaaaf9d4bd6 410 SUPERFAMILY SSF56796 3 406 1.57E-97 T 14-10-2018 A4R43_40425 c6fbd08d1edf17086a311eaaaf9d4bd6 410 Gene3D G3DSA:3.40.50.1970 1 179 1.8E-48 T 14-10-2018 A4R43_40425 c6fbd08d1edf17086a311eaaaf9d4bd6 410 Gene3D G3DSA:1.20.1090.10 180 406 1.1E-54 T 14-10-2018 A4R43_40425 c6fbd08d1edf17086a311eaaaf9d4bd6 410 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 168 196 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A4R43_40425 c6fbd08d1edf17086a311eaaaf9d4bd6 410 Pfam PF00465 Iron-containing alcohol dehydrogenase 3 399 2.9E-103 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A4R43_31665 f54356c9d25d73d675025b5923e28819 367 Gene3D G3DSA:3.20.20.190 39 366 8.0E-107 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A4R43_31665 f54356c9d25d73d675025b5923e28819 367 SUPERFAMILY SSF51695 40 365 1.15E-75 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A4R43_31665 f54356c9d25d73d675025b5923e28819 367 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 46 361 5.3E-46 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A4R43_35730 862abe06586f74cada4984dc509aefb3 89 SUPERFAMILY SSF88723 5 83 4.51E-5 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_35730 862abe06586f74cada4984dc509aefb3 89 Gene3D G3DSA:3.40.50.1010 3 83 1.5E-5 T 14-10-2018 A4R43_23960 6c7ba70b59111191aab4ecd0b71e49de 319 TIGRFAM TIGR00444 mazG: MazG family protein 101 248 6.6E-44 T 14-10-2018 IPR011551 NTP pyrophosphohydrolase MazG A4R43_23960 6c7ba70b59111191aab4ecd0b71e49de 319 Gene3D G3DSA:1.10.287.1080 255 319 2.4E-5 T 14-10-2018 A4R43_23960 6c7ba70b59111191aab4ecd0b71e49de 319 Gene3D G3DSA:1.10.287.1080 92 218 1.5E-42 T 14-10-2018 A4R43_23960 6c7ba70b59111191aab4ecd0b71e49de 319 SUPERFAMILY SSF101386 98 193 1.37E-23 T 14-10-2018 A4R43_23960 6c7ba70b59111191aab4ecd0b71e49de 319 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 117 192 9.0E-27 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A4R43_07830 d883deb512a941f9a2301084c495dc5c 430 Pfam PF00355 Rieske [2Fe-2S] domain 61 143 1.4E-15 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4R43_07830 d883deb512a941f9a2301084c495dc5c 430 SUPERFAMILY SSF50022 30 191 3.14E-38 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_07830 d883deb512a941f9a2301084c495dc5c 430 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 212 408 3.5E-34 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 A4R43_07830 d883deb512a941f9a2301084c495dc5c 430 SUPERFAMILY SSF55961 192 412 2.59E-41 T 14-10-2018 A4R43_07830 d883deb512a941f9a2301084c495dc5c 430 Gene3D G3DSA:3.90.380.10 262 414 6.1E-21 T 14-10-2018 A4R43_07830 d883deb512a941f9a2301084c495dc5c 430 Gene3D G3DSA:2.102.10.10 59 197 7.4E-35 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_07830 d883deb512a941f9a2301084c495dc5c 430 Gene3D G3DSA:3.90.380.10 198 261 5.4E-6 T 14-10-2018 A4R43_12365 4c4609295f154655436aa3e4b8633a18 227 SUPERFAMILY SSF140453 58 139 4.71E-9 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_12365 4c4609295f154655436aa3e4b8633a18 227 Gene3D G3DSA:1.10.287.1060 55 143 5.4E-8 T 14-10-2018 A4R43_12365 4c4609295f154655436aa3e4b8633a18 227 Pfam PF06013 Proteins of 100 residues with WXG 60 138 2.6E-7 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SMART SM00490 848 932 2.2E-16 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SUPERFAMILY SSF143517 1021 1178 9.55E-33 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Gene3D G3DSA:3.40.50.300 498 1009 4.0E-228 T 14-10-2018 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SMART SM00982 1031 1128 6.6E-38 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SUPERFAMILY SSF52540 371 470 1.06E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SMART SM00487 622 814 6.9E-28 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Gene3D G3DSA:3.40.50.300 564 803 4.0E-228 T 14-10-2018 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SUPERFAMILY SSF52540 804 1012 1.13E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1104 0.0 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SUPERFAMILY SSF141259 490 570 1.31E-18 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Pfam PF02559 CarD-like/TRCF domain 498 597 1.2E-31 T 14-10-2018 IPR003711 CarD-like/TRCF domain A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Gene3D G3DSA:3.40.50.11180 49 310 2.3E-60 T 14-10-2018 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Pfam PF00270 DEAD/DEAH box helicase 647 788 2.7E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SMART SM01058 497 598 1.3E-48 T 14-10-2018 IPR003711 CarD-like/TRCF domain A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Pfam PF03461 TRCF domain 1032 1113 6.4E-24 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SUPERFAMILY SSF52540 548 805 2.19E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 39 1128 27.392 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 SUPERFAMILY SSF52540 21 362 8.32E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Gene3D G3DSA:3.30.2060.10 142 228 2.3E-60 T 14-10-2018 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Gene3D G3DSA:2.30.30.840 501 563 4.0E-228 T 14-10-2018 A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Gene3D G3DSA:3.90.1150.50 1027 1146 1.4E-24 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain A4R43_23970 f1b687e4c4128faf5753198f76091728 1185 Pfam PF00271 Helicase conserved C-terminal domain 832 931 1.5E-14 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_14690 1a3a29e7b03f855b30a5eabeef3085b9 458 SUPERFAMILY SSF53474 84 413 2.98E-9 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14690 1a3a29e7b03f855b30a5eabeef3085b9 458 Gene3D G3DSA:3.40.50.1820 51 261 2.8E-12 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14690 1a3a29e7b03f855b30a5eabeef3085b9 458 Pfam PF05576 PS-10 peptidase S37 25 445 6.0E-143 T 14-10-2018 IPR008761 Peptidase S37, tripeptidyl aminopeptidase A4R43_14435 cd8fd56867db6df24b478eaccf4fa6fb 319 Gene3D G3DSA:1.10.3720.10 71 317 3.9E-56 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_14435 cd8fd56867db6df24b478eaccf4fa6fb 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 314 9.5E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_14435 cd8fd56867db6df24b478eaccf4fa6fb 319 SUPERFAMILY SSF161098 26 314 1.83E-51 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 Gene3D G3DSA:1.10.3710.10 364 455 1.2E-22 T 14-10-2018 A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 Gene3D G3DSA:1.20.272.10 257 361 6.5E-48 T 14-10-2018 A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 SMART SM00382 68 185 8.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 Pfam PF12002 MgsA AAA+ ATPase C terminal 284 449 4.8E-69 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 Pfam PF16193 AAA C-terminal domain 207 283 3.2E-28 T 14-10-2018 IPR032423 AAA C-terminal domain A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 Gene3D G3DSA:3.40.50.300 31 183 4.8E-40 T 14-10-2018 A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 SUPERFAMILY SSF48019 269 452 2.55E-74 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 Gene3D G3DSA:1.10.8.60 185 254 7.6E-14 T 14-10-2018 A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 SUPERFAMILY SSF52540 33 246 4.99E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04500 c480ec27a9c3441abcd89b8da46d4ab0 456 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 72 176 2.4E-16 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_04495 2e0318059ef7b5b93c2ef3c7b8a47433 253 PIRSF PIRSF000883 3 234 1.4E-41 T 14-10-2018 IPR011152 Phosphoesterase MJ0912 A4R43_04495 2e0318059ef7b5b93c2ef3c7b8a47433 253 SUPERFAMILY SSF56300 1 229 2.69E-40 T 14-10-2018 A4R43_04495 2e0318059ef7b5b93c2ef3c7b8a47433 253 Gene3D G3DSA:3.60.21.10 1 236 1.5E-46 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_04495 2e0318059ef7b5b93c2ef3c7b8a47433 253 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 191 1.5E-23 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 46 58 3.7E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 30 46 3.7E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 16 30 3.7E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 SUPERFAMILY SSF46894 11 63 2.41E-10 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 Pfam PF00486 Transcriptional regulatory protein, C terminal 93 158 1.3E-12 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 SMART SM00421 13 70 3.0E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 Gene3D G3DSA:1.10.10.10 65 159 1.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 SMART SM01043 165 309 2.3E-46 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 SMART SM00862 84 158 3.2E-13 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 Gene3D G3DSA:1.10.10.10 7 64 2.7E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 SUPERFAMILY SSF46894 71 158 6.8E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 Gene3D G3DSA:1.25.40.10 164 314 6.4E-44 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 Pfam PF03704 Bacterial transcriptional activator domain 165 309 5.1E-37 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 SUPERFAMILY SSF48452 163 313 1.0E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03705 0334accd841578239b2b29ad1ad58bc3 314 Pfam PF00196 Bacterial regulatory proteins, luxR family 15 63 9.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Pfam PF08310 LGFP repeat 649 697 6.6E-10 T 14-10-2018 IPR013207 LGFP A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Pfam PF08310 LGFP repeat 870 923 1.9E-20 T 14-10-2018 IPR013207 LGFP A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Pfam PF08310 LGFP repeat 755 811 3.1E-14 T 14-10-2018 IPR013207 LGFP A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Pfam PF08310 LGFP repeat 700 753 5.5E-19 T 14-10-2018 IPR013207 LGFP A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Pfam PF08310 LGFP repeat 813 868 2.8E-11 T 14-10-2018 IPR013207 LGFP A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Pfam PF08310 LGFP repeat 925 960 4.3E-6 T 14-10-2018 IPR013207 LGFP A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Pfam PF07995 Glucose / Sorbosone dehydrogenase 23 324 6.2E-37 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 SUPERFAMILY SSF49299 368 452 6.54E-13 T 14-10-2018 IPR035986 PKD domain superfamily A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Gene3D G3DSA:2.120.10.30 15 364 8.3E-61 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Pfam PF00801 PKD domain 381 445 3.0E-10 T 14-10-2018 IPR000601 PKD domain A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 Gene3D G3DSA:2.60.40.10 365 452 6.7E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 SUPERFAMILY SSF50952 19 320 1.7E-16 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_32545 0044c528cdd0284708ee883befbf49fc 963 SMART SM00089 370 454 1.6E-8 T 14-10-2018 IPR022409 PKD/Chitinase domain A4R43_17250 9a63663272ea2da89cb12a044ca749e6 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.2E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17250 9a63663272ea2da89cb12a044ca749e6 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.2E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17250 9a63663272ea2da89cb12a044ca749e6 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 2.5E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_17250 9a63663272ea2da89cb12a044ca749e6 202 SUPERFAMILY SSF46689 6 75 2.77E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17250 9a63663272ea2da89cb12a044ca749e6 202 Gene3D G3DSA:1.10.10.60 7 67 8.3E-23 T 14-10-2018 A4R43_17250 9a63663272ea2da89cb12a044ca749e6 202 Gene3D G3DSA:1.10.357.10 69 197 4.9E-41 T 14-10-2018 A4R43_17250 9a63663272ea2da89cb12a044ca749e6 202 SUPERFAMILY SSF48498 87 197 5.93E-32 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_14605 dfe0108698ff127ac8a6225050b48375 143 Pfam PF13508 Acetyltransferase (GNAT) domain 48 121 3.2E-9 T 14-10-2018 IPR000182 GNAT domain A4R43_14605 dfe0108698ff127ac8a6225050b48375 143 Gene3D G3DSA:3.40.630.30 1 139 4.7E-25 T 14-10-2018 A4R43_14605 dfe0108698ff127ac8a6225050b48375 143 SUPERFAMILY SSF55729 2 141 6.03E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_14610 79ef46860bd1cc25623dfff6838e4fa1 329 SUPERFAMILY SSF51430 9 319 1.31E-85 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_14610 79ef46860bd1cc25623dfff6838e4fa1 329 Pfam PF00248 Aldo/keto reductase family 16 316 3.7E-68 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_14610 79ef46860bd1cc25623dfff6838e4fa1 329 Gene3D G3DSA:3.20.20.100 3 327 4.7E-101 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 Gene3D G3DSA:3.40.30.120 368 448 3.6E-8 T 14-10-2018 A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 SUPERFAMILY SSF51905 1 341 5.94E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 3.4E-33 T 14-10-2018 A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 303 3.4E-33 T 14-10-2018 A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 3.4E-33 T 14-10-2018 A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.4E-33 T 14-10-2018 A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 Pfam PF01494 FAD binding domain 2 328 2.4E-75 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 Gene3D G3DSA:3.30.70.2450 180 261 2.7E-101 T 14-10-2018 A4R43_35525 fd4743bf6437ffb818bdd2753fcbe99f 448 Gene3D G3DSA:3.50.50.60 3 328 2.7E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_36035 9312b02096241cd776e646ca2b47cb61 333 Gene3D G3DSA:3.90.79.20 52 181 4.3E-9 T 14-10-2018 A4R43_36035 9312b02096241cd776e646ca2b47cb61 333 ProSitePatterns PS00893 Nudix box signature. 220 241 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_36035 9312b02096241cd776e646ca2b47cb61 333 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 43 147 1.4E-5 T 14-10-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 A4R43_36035 9312b02096241cd776e646ca2b47cb61 333 Gene3D G3DSA:3.90.79.10 183 331 9.4E-34 T 14-10-2018 A4R43_36035 9312b02096241cd776e646ca2b47cb61 333 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 150 180 2.8E-6 T 14-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 A4R43_36035 9312b02096241cd776e646ca2b47cb61 333 SUPERFAMILY SSF55811 135 303 5.15E-42 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_36035 9312b02096241cd776e646ca2b47cb61 333 Pfam PF00293 NUDIX domain 185 296 3.5E-17 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_00035 43bcce8146d3e24d2fc4f8d882f0ffec 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 210 7.5E-6 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_00035 43bcce8146d3e24d2fc4f8d882f0ffec 327 SUPERFAMILY SSF51735 1 286 3.87E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_00035 43bcce8146d3e24d2fc4f8d882f0ffec 327 Gene3D G3DSA:3.40.50.720 1 260 6.6E-23 T 14-10-2018 A4R43_07715 95c636beae0d2c79b56ac9347ade835e 484 Gene3D G3DSA:1.20.1250.20 16 216 1.6E-30 T 14-10-2018 A4R43_07715 95c636beae0d2c79b56ac9347ade835e 484 SUPERFAMILY SSF103473 16 479 3.49E-57 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_07715 95c636beae0d2c79b56ac9347ade835e 484 Pfam PF07690 Major Facilitator Superfamily 28 395 5.8E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_07715 95c636beae0d2c79b56ac9347ade835e 484 Gene3D G3DSA:1.20.1250.20 283 480 1.2E-27 T 14-10-2018 A4R43_37305 199cacec9556d1085155e9444e6b9a5f 166 SUPERFAMILY SSF54637 11 146 1.34E-23 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_37305 199cacec9556d1085155e9444e6b9a5f 166 Gene3D G3DSA:3.10.129.10 3 155 6.8E-38 T 14-10-2018 A4R43_37305 199cacec9556d1085155e9444e6b9a5f 166 Pfam PF13279 Thioesterase-like superfamily 17 141 4.3E-7 T 14-10-2018 A4R43_26050 130467a3377bb4ccb6898a5d66ec641a 323 Gene3D G3DSA:3.20.20.120 63 289 3.2E-130 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_26050 130467a3377bb4ccb6898a5d66ec641a 323 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 1 306 22.959 T 14-10-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 A4R43_26050 130467a3377bb4ccb6898a5d66ec641a 323 Gene3D G3DSA:3.30.390.10 10 310 3.2E-130 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_26050 130467a3377bb4ccb6898a5d66ec641a 323 Pfam PF13378 Enolase C-terminal domain-like 85 286 4.1E-37 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_26050 130467a3377bb4ccb6898a5d66ec641a 323 SMART SM00922 83 179 3.7E-23 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_26050 130467a3377bb4ccb6898a5d66ec641a 323 SUPERFAMILY SSF51604 69 286 8.91E-52 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_36895 40809a7af441c2600178f1e838025085 153 Gene3D G3DSA:3.40.1400.10 1 152 1.3E-47 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_36895 40809a7af441c2600178f1e838025085 153 SUPERFAMILY SSF89623 1 151 6.67E-47 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_36895 40809a7af441c2600178f1e838025085 153 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 150 5.7E-53 T 14-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 A4R43_36895 40809a7af441c2600178f1e838025085 153 PIRSF PIRSF005384 1 151 2.6E-45 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_36895 40809a7af441c2600178f1e838025085 153 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 149 3.9E-35 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_36895 40809a7af441c2600178f1e838025085 153 Pfam PF02502 Ribose/Galactose Isomerase 3 144 4.2E-44 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_16390 aa49ef5539440a5e149dc76fea1e6a52 598 Gene3D G3DSA:3.40.50.12780 324 464 1.5E-39 T 14-10-2018 A4R43_16390 aa49ef5539440a5e149dc76fea1e6a52 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_16390 aa49ef5539440a5e149dc76fea1e6a52 598 Gene3D G3DSA:3.40.50.12780 3 310 1.2E-54 T 14-10-2018 A4R43_16390 aa49ef5539440a5e149dc76fea1e6a52 598 Pfam PF00501 AMP-binding enzyme 24 466 3.0E-97 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_16390 aa49ef5539440a5e149dc76fea1e6a52 598 SUPERFAMILY SSF56801 17 596 4.19E-114 T 14-10-2018 A4R43_04100 c3ecc445db531f3d6a3ef49ce19e41c1 277 SUPERFAMILY SSF52540 12 241 6.1E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04100 c3ecc445db531f3d6a3ef49ce19e41c1 277 Pfam PF00005 ABC transporter 28 175 1.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_04100 c3ecc445db531f3d6a3ef49ce19e41c1 277 SMART SM00382 35 225 2.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_04100 c3ecc445db531f3d6a3ef49ce19e41c1 277 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_04100 c3ecc445db531f3d6a3ef49ce19e41c1 277 Gene3D G3DSA:3.40.50.300 11 264 7.5E-65 T 14-10-2018 A4R43_40410 ff11a316e9a52b1497c3d955b5bb2573 206 Gene3D G3DSA:1.10.357.10 7 197 1.9E-19 T 14-10-2018 A4R43_40410 ff11a316e9a52b1497c3d955b5bb2573 206 SUPERFAMILY SSF46689 3 80 1.95E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_40410 ff11a316e9a52b1497c3d955b5bb2573 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.4E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40410 ff11a316e9a52b1497c3d955b5bb2573 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40410 ff11a316e9a52b1497c3d955b5bb2573 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 9.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35060 028b444a81968e99a81a305d603a5a81 206 SMART SM01007 9 195 2.2E-37 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_35060 028b444a81968e99a81a305d603a5a81 206 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 16 197 2.0E-50 T 14-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A4R43_35060 028b444a81968e99a81a305d603a5a81 206 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 204 79.754 T 14-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A4R43_35060 028b444a81968e99a81a305d603a5a81 206 SUPERFAMILY SSF53639 11 196 7.06E-37 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_35060 028b444a81968e99a81a305d603a5a81 206 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 192 7.8E-35 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_35060 028b444a81968e99a81a305d603a5a81 206 Gene3D G3DSA:3.40.225.10 8 200 8.7E-43 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_14150 dbc8ea6f876080baa1521455b052b475 160 Pfam PF02080 TrkA-C domain 90 157 1.1E-13 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4R43_14150 dbc8ea6f876080baa1521455b052b475 160 SUPERFAMILY SSF116726 87 157 1.29E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_14150 dbc8ea6f876080baa1521455b052b475 160 Gene3D G3DSA:3.30.70.1450 88 159 1.6E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_14150 dbc8ea6f876080baa1521455b052b475 160 PIRSF PIRSF005028 1 160 5.0E-53 T 14-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT A4R43_34350 9652a56b54fa501775381dc10a23245f 378 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 19 308 8.0E-34 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4R43_34350 9652a56b54fa501775381dc10a23245f 378 SUPERFAMILY SSF51412 9 377 7.94E-60 T 14-10-2018 A4R43_34350 9652a56b54fa501775381dc10a23245f 378 SMART SM01240 15 376 8.7E-16 T 14-10-2018 A4R43_34350 9652a56b54fa501775381dc10a23245f 378 Gene3D G3DSA:3.20.20.70 16 377 1.1E-86 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_34350 9652a56b54fa501775381dc10a23245f 378 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 5 376 2.2E-164 T 14-10-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 Pfam PF00072 Response regulator receiver domain 7 118 8.3E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 SUPERFAMILY SSF46894 145 216 5.1E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 Gene3D G3DSA:3.40.50.2300 4 101 2.9E-7 T 14-10-2018 A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 SMART SM00421 154 211 2.1E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 SUPERFAMILY SSF52172 3 134 8.54E-15 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 211 2.6E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 Gene3D G3DSA:1.10.10.10 103 223 6.9E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 4.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 4.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38200 232f96ba9f21d6b176124e659dd47101 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 4.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_28665 82400fe1fcbc12a03be8d62243930532 361 Pfam PF00144 Beta-lactamase 42 276 6.3E-47 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_28665 82400fe1fcbc12a03be8d62243930532 361 Gene3D G3DSA:3.40.710.10 27 333 3.5E-81 T 14-10-2018 A4R43_28665 82400fe1fcbc12a03be8d62243930532 361 SUPERFAMILY SSF56601 42 329 8.95E-64 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_32030 99126fb2c7a397be303912fe4d047a44 375 SUPERFAMILY SSF103025 25 278 3.92E-52 T 14-10-2018 A4R43_32030 99126fb2c7a397be303912fe4d047a44 375 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 263 353 5.2E-9 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4R43_32030 99126fb2c7a397be303912fe4d047a44 375 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 225 289 7.9E-17 T 14-10-2018 IPR017703 YgfZ/GcvT conserved site A4R43_32030 99126fb2c7a397be303912fe4d047a44 375 SUPERFAMILY SSF101790 282 355 6.21E-5 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A4R43_32030 99126fb2c7a397be303912fe4d047a44 375 Pfam PF01571 Aminomethyltransferase folate-binding domain 25 253 1.2E-26 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A4R43_32030 99126fb2c7a397be303912fe4d047a44 375 PIRSF PIRSF006487 23 367 7.0E-23 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4R43_32030 99126fb2c7a397be303912fe4d047a44 375 Gene3D G3DSA:3.30.1360.120 23 355 9.1E-63 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4R43_05205 3764d690398b56d5a7be63da70e57652 263 SUPERFAMILY SSF109854 3 152 1.36E-38 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_05205 3764d690398b56d5a7be63da70e57652 263 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 146 3.4E-33 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_05205 3764d690398b56d5a7be63da70e57652 263 Gene3D G3DSA:1.20.120.450 4 149 2.7E-21 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_05205 3764d690398b56d5a7be63da70e57652 263 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 224 3.5E-50 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_05205 3764d690398b56d5a7be63da70e57652 263 Pfam PF08608 Wyosine base formation 184 234 1.8E-5 T 14-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4R43_05205 3764d690398b56d5a7be63da70e57652 263 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 6 257 7.8E-107 T 14-10-2018 IPR017518 Conserved hypothetical protein CHP03084 A4R43_37005 55c22952abb9f69ecc05e9add99cc485 598 Pfam PF00733 Asparagine synthase 239 587 6.3E-65 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4R43_37005 55c22952abb9f69ecc05e9add99cc485 598 Pfam PF13537 Glutamine amidotransferase domain 45 165 9.1E-36 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4R43_37005 55c22952abb9f69ecc05e9add99cc485 598 PIRSF PIRSF001589 1 598 3.0E-118 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_37005 55c22952abb9f69ecc05e9add99cc485 598 SUPERFAMILY SSF56235 1 211 3.52E-46 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_37005 55c22952abb9f69ecc05e9add99cc485 598 SUPERFAMILY SSF52402 231 576 4.19E-57 T 14-10-2018 A4R43_37005 55c22952abb9f69ecc05e9add99cc485 598 Gene3D G3DSA:3.60.20.10 3 183 1.2E-45 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_37005 55c22952abb9f69ecc05e9add99cc485 598 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 521 2.2E-102 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_40950 ac17bca41996a6d109d87e8708f660e3 342 Gene3D G3DSA:3.20.20.100 15 342 2.0E-117 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_40950 ac17bca41996a6d109d87e8708f660e3 342 SUPERFAMILY SSF51430 13 327 1.44E-89 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_40950 ac17bca41996a6d109d87e8708f660e3 342 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 283 296 2.0E-5 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 A4R43_40950 ac17bca41996a6d109d87e8708f660e3 342 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 270 282 2.0E-5 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 A4R43_40950 ac17bca41996a6d109d87e8708f660e3 342 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 126 136 2.0E-5 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 A4R43_40950 ac17bca41996a6d109d87e8708f660e3 342 Pfam PF00248 Aldo/keto reductase family 28 327 2.6E-70 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_24080 28dd14a95c4bac7afac49351fb1aae76 472 Gene3D G3DSA:1.10.530.10 391 472 6.1E-34 T 14-10-2018 A4R43_24080 28dd14a95c4bac7afac49351fb1aae76 472 Pfam PF06737 Transglycosylase-like domain 391 465 4.9E-32 T 14-10-2018 IPR010618 Transglycosylase-like A4R43_24080 28dd14a95c4bac7afac49351fb1aae76 472 Pfam PF03990 Domain of unknown function (DUF348) 133 173 1.4E-14 T 14-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A4R43_24080 28dd14a95c4bac7afac49351fb1aae76 472 Gene3D G3DSA:2.20.230.10 302 388 4.3E-21 T 14-10-2018 A4R43_24080 28dd14a95c4bac7afac49351fb1aae76 472 SUPERFAMILY SSF53955 388 471 1.31E-31 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_24080 28dd14a95c4bac7afac49351fb1aae76 472 Pfam PF07501 G5 domain 308 381 1.1E-20 T 14-10-2018 IPR011098 G5 domain A4R43_24080 28dd14a95c4bac7afac49351fb1aae76 472 SMART SM01208 304 382 3.2E-24 T 14-10-2018 IPR011098 G5 domain A4R43_18280 c176c3323c7c0326d2a55b6b54299a9e 593 SUPERFAMILY SSF55781 43 211 1.0E-29 T 14-10-2018 A4R43_18280 c176c3323c7c0326d2a55b6b54299a9e 593 Gene3D G3DSA:1.10.10.2840 455 586 1.5E-26 T 14-10-2018 A4R43_18280 c176c3323c7c0326d2a55b6b54299a9e 593 Pfam PF13556 PucR C-terminal helix-turn-helix domain 523 581 1.3E-19 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_18280 c176c3323c7c0326d2a55b6b54299a9e 593 Gene3D G3DSA:3.30.450.40 43 215 5.0E-43 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_18280 c176c3323c7c0326d2a55b6b54299a9e 593 SMART SM00065 63 214 8.8E-25 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_18280 c176c3323c7c0326d2a55b6b54299a9e 593 Pfam PF13185 GAF domain 63 205 1.5E-17 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 PRINTS PR00359 B-class P450 signature 184 200 8.3E-31 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 PRINTS PR00359 B-class P450 signature 332 343 8.3E-31 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 PRINTS PR00359 B-class P450 signature 349 376 8.3E-31 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 PRINTS PR00359 B-class P450 signature 408 419 8.3E-31 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 PRINTS PR00359 B-class P450 signature 399 408 8.3E-31 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 PRINTS PR00359 B-class P450 signature 201 216 8.3E-31 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 PRINTS PR00359 B-class P450 signature 377 392 8.3E-31 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 PRINTS PR00359 B-class P450 signature 138 149 8.3E-31 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 Pfam PF00067 Cytochrome P450 329 432 4.0E-19 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 401 410 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 Gene3D G3DSA:1.10.630.10 32 461 3.9E-109 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_29835 c86e99c18245bb7331bcf24302ff8cc7 462 SUPERFAMILY SSF48264 66 459 1.7E-81 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37755 30cfb5355ca2b92b5811b21626006da6 471 SUPERFAMILY SSF52096 21 214 2.4E-49 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_37755 30cfb5355ca2b92b5811b21626006da6 471 Pfam PF01039 Carboxyl transferase domain 39 459 1.2E-126 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_37755 30cfb5355ca2b92b5811b21626006da6 471 Gene3D G3DSA:3.90.226.10 16 218 2.1E-58 T 14-10-2018 A4R43_37755 30cfb5355ca2b92b5811b21626006da6 471 Gene3D G3DSA:3.90.226.10 219 471 2.1E-79 T 14-10-2018 A4R43_37755 30cfb5355ca2b92b5811b21626006da6 471 SUPERFAMILY SSF52096 221 459 6.42E-75 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_38790 9e2a82e8b89a878b12adaa83daac8f9d 212 SMART SM00855 2 160 3.0E-19 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_38790 9e2a82e8b89a878b12adaa83daac8f9d 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 197 4.8E-34 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_38790 9e2a82e8b89a878b12adaa83daac8f9d 212 PIRSF PIRSF000709 2 188 1.4E-6 T 14-10-2018 A4R43_38790 9e2a82e8b89a878b12adaa83daac8f9d 212 SUPERFAMILY SSF53254 2 196 8.87E-41 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_38790 9e2a82e8b89a878b12adaa83daac8f9d 212 Gene3D G3DSA:3.40.50.1240 1 206 2.1E-41 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_19095 4c3a450f6742fe3abc5dfcdec6569eb5 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 63 4.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19095 4c3a450f6742fe3abc5dfcdec6569eb5 233 SUPERFAMILY SSF46689 8 81 3.13E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19095 4c3a450f6742fe3abc5dfcdec6569eb5 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 9.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19095 4c3a450f6742fe3abc5dfcdec6569eb5 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 9.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19095 4c3a450f6742fe3abc5dfcdec6569eb5 233 Gene3D G3DSA:1.10.357.10 1 229 1.9E-63 T 14-10-2018 A4R43_19095 4c3a450f6742fe3abc5dfcdec6569eb5 233 SUPERFAMILY SSF48498 91 227 2.89E-24 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_19445 10d8890594a9fae3baea33a146b6469a 292 SMART SM00797 26 289 3.8E-95 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A4R43_19445 10d8890594a9fae3baea33a146b6469a 292 Gene3D G3DSA:2.40.100.10 174 287 8.1E-40 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_19445 10d8890594a9fae3baea33a146b6469a 292 SUPERFAMILY SSF50891 176 286 4.17E-14 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily A4R43_19445 10d8890594a9fae3baea33a146b6469a 292 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 5 283 1.3E-82 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A4R43_19445 10d8890594a9fae3baea33a146b6469a 292 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 27 283 1.5E-82 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A4R43_22770 45ef3a91e6b3559e7ea13a7728ea97c1 469 ProSitePatterns PS00571 Amidases signature. 155 186 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4R43_22770 45ef3a91e6b3559e7ea13a7728ea97c1 469 SUPERFAMILY SSF75304 6 456 4.97E-134 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_22770 45ef3a91e6b3559e7ea13a7728ea97c1 469 Pfam PF01425 Amidase 26 447 2.8E-104 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_22770 45ef3a91e6b3559e7ea13a7728ea97c1 469 Gene3D G3DSA:3.90.1300.10 2 466 1.1E-141 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_27095 b42cf8ad6d05fd83f76f3a2b838a92a1 112 SUPERFAMILY SSF51182 28 103 3.63E-20 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_27095 b42cf8ad6d05fd83f76f3a2b838a92a1 112 Pfam PF07883 Cupin domain 37 94 1.1E-13 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_27095 b42cf8ad6d05fd83f76f3a2b838a92a1 112 Gene3D G3DSA:2.60.120.10 16 107 3.6E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_34530 b778f3bf9e5e1fec611b5865aeb49697 1108 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 66 1108 12.398 T 14-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_34530 b778f3bf9e5e1fec611b5865aeb49697 1108 SMART SM00481 67 134 1.1E-23 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A4R43_34530 b778f3bf9e5e1fec611b5865aeb49697 1108 Pfam PF14579 Helix-hairpin-helix motif 849 942 2.6E-26 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_34530 b778f3bf9e5e1fec611b5865aeb49697 1108 Gene3D G3DSA:3.20.20.140 49 339 9.1E-72 T 14-10-2018 A4R43_34530 b778f3bf9e5e1fec611b5865aeb49697 1108 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 67 945 1.1E-193 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_34530 b778f3bf9e5e1fec611b5865aeb49697 1108 SUPERFAMILY SSF89550 66 275 5.49E-18 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4R43_34530 b778f3bf9e5e1fec611b5865aeb49697 1108 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 361 775 6.2E-139 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_34530 b778f3bf9e5e1fec611b5865aeb49697 1108 Pfam PF02811 PHP domain 68 234 4.4E-25 T 14-10-2018 IPR004013 PHP domain GO:0003824 A4R43_17270 2bde6f9fdf3bca595d3136da6161589c 387 Gene3D G3DSA:2.120.10.30 20 386 3.5E-78 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_17270 2bde6f9fdf3bca595d3136da6161589c 387 SUPERFAMILY SSF50956 32 384 5.49E-50 T 14-10-2018 A4R43_17270 2bde6f9fdf3bca595d3136da6161589c 387 Pfam PF02333 Phytase 220 371 5.2E-19 T 14-10-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 A4R43_17270 2bde6f9fdf3bca595d3136da6161589c 387 Pfam PF02333 Phytase 29 140 2.5E-10 T 14-10-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 A4R43_14635 2e7f94bb62775254d4ae174e7244a0d6 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 313 1.1E-46 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 3.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 3.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 3.4E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 SUPERFAMILY SSF46785 13 102 1.64E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 Gene3D G3DSA:1.20.120.530 79 215 6.7E-33 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 SMART SM00345 17 75 1.2E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 SUPERFAMILY SSF48008 82 211 1.65E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 Pfam PF07729 FCD domain 85 204 3.4E-29 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 SMART SM00895 85 205 4.2E-25 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_23785 2dccda9560483fc73d16525b1fcfcb05 218 Gene3D G3DSA:1.10.10.10 2 76 1.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 PRINTS PR00702 Acriflavin resistance protein family signature 216 239 8.6E-7 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 PRINTS PR00702 Acriflavin resistance protein family signature 269 293 8.6E-7 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 PRINTS PR00702 Acriflavin resistance protein family signature 345 368 8.6E-7 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 SUPERFAMILY SSF82866 160 374 2.75E-25 T 14-10-2018 A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 Gene3D G3DSA:1.20.1640.10 552 738 4.7E-7 T 14-10-2018 A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 Gene3D G3DSA:1.20.1640.10 180 381 1.7E-7 T 14-10-2018 A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 SUPERFAMILY SSF82866 527 740 1.02E-28 T 14-10-2018 A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 Pfam PF03176 MMPL family 45 414 1.5E-54 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_29865 72c36b1a54a7408e22a83e77435cf9d3 779 Pfam PF03176 MMPL family 506 741 6.3E-30 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_39210 6c66509120b2ab67169cc24735139858 455 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_39210 6c66509120b2ab67169cc24735139858 455 SUPERFAMILY SSF103473 4 430 3.14E-70 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_39210 6c66509120b2ab67169cc24735139858 455 Pfam PF07690 Major Facilitator Superfamily 15 266 8.3E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_39210 6c66509120b2ab67169cc24735139858 455 Gene3D G3DSA:1.20.1250.20 250 432 7.7E-29 T 14-10-2018 A4R43_39210 6c66509120b2ab67169cc24735139858 455 Gene3D G3DSA:1.20.1250.20 6 198 9.5E-44 T 14-10-2018 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 Pfam PF01264 Chorismate synthase 2 369 4.9E-113 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 SUPERFAMILY SSF103263 2 392 3.53E-131 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 TIGRFAM TIGR00033 aroC: chorismate synthase 2 374 1.1E-120 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 Gene3D G3DSA:3.60.150.10 1 395 7.6E-153 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 Hamap MF_00300 Chorismate synthase [aroC]. 2 376 33.966 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 PIRSF PIRSF001456 1 386 7.4E-122 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_04655 832bccb74c444924b28f3776bda045ec 395 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4R43_38685 848afe288a4860a29c29e12bd008cf91 158 Pfam PF00583 Acetyltransferase (GNAT) family 50 151 2.3E-6 T 14-10-2018 IPR000182 GNAT domain A4R43_38685 848afe288a4860a29c29e12bd008cf91 158 Gene3D G3DSA:3.40.630.30 2 157 2.9E-14 T 14-10-2018 A4R43_38685 848afe288a4860a29c29e12bd008cf91 158 SUPERFAMILY SSF55729 35 155 2.48E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_05240 5b0c3f2db6fb1ce75276ab46b34a2bc4 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 6.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05240 5b0c3f2db6fb1ce75276ab46b34a2bc4 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 6.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05240 5b0c3f2db6fb1ce75276ab46b34a2bc4 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.6E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05240 5b0c3f2db6fb1ce75276ab46b34a2bc4 207 SUPERFAMILY SSF46689 2 76 2.19E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_05240 5b0c3f2db6fb1ce75276ab46b34a2bc4 207 Gene3D G3DSA:1.10.357.10 2 197 3.0E-27 T 14-10-2018 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 PIRSF PIRSF001365 1 309 5.6E-71 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 Pfam PF00701 Dihydrodipicolinate synthetase family 6 303 6.4E-49 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 3.9E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 3.9E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 3.9E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 3.9E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 SUPERFAMILY SSF51569 2 308 1.15E-73 T 14-10-2018 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 SMART SM01130 5 307 1.8E-82 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_06765 73f9688120eb5ee016b7984121c78390 309 Gene3D G3DSA:3.20.20.70 1 307 7.6E-92 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_23705 a15a8f491fab03837432138139919527 400 Gene3D G3DSA:3.40.50.1100 9 308 1.2E-113 T 14-10-2018 A4R43_23705 a15a8f491fab03837432138139919527 400 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4R43_23705 a15a8f491fab03837432138139919527 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 304 1.5E-81 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_23705 a15a8f491fab03837432138139919527 400 SUPERFAMILY SSF55021 329 394 4.58E-5 T 14-10-2018 A4R43_23705 a15a8f491fab03837432138139919527 400 Gene3D G3DSA:3.40.50.1100 52 148 1.2E-113 T 14-10-2018 A4R43_23705 a15a8f491fab03837432138139919527 400 SUPERFAMILY SSF53686 6 311 5.63E-92 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_23705 a15a8f491fab03837432138139919527 400 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 23 399 5.4E-129 T 14-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4R43_15320 b71faa4bd2f3e51a12974941aea7ef87 479 Gene3D G3DSA:3.30.450.40 3 182 6.9E-35 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_15320 b71faa4bd2f3e51a12974941aea7ef87 479 Gene3D G3DSA:1.10.10.60 429 476 1.9E-10 T 14-10-2018 A4R43_15320 b71faa4bd2f3e51a12974941aea7ef87 479 Pfam PF02954 Bacterial regulatory protein, Fis family 433 472 5.9E-8 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4R43_15320 b71faa4bd2f3e51a12974941aea7ef87 479 Gene3D G3DSA:1.10.8.60 352 425 5.0E-14 T 14-10-2018 A4R43_15320 b71faa4bd2f3e51a12974941aea7ef87 479 SUPERFAMILY SSF52540 222 413 6.3E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15320 b71faa4bd2f3e51a12974941aea7ef87 479 SUPERFAMILY SSF46689 422 474 1.0E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_01590 f0d86943916736714bc840c0433feb6f 170 Pfam PF11158 Protein of unknown function (DUF2938) 13 158 3.9E-52 T 14-10-2018 IPR021329 Protein of unknown function DUF2938 A4R43_05800 bd0cbc89f4ddeb779374ceb6c4915353 410 Gene3D G3DSA:3.40.50.10540 6 404 3.6E-143 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_05800 bd0cbc89f4ddeb779374ceb6c4915353 410 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 4 410 1.3E-203 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 A4R43_05800 bd0cbc89f4ddeb779374ceb6c4915353 410 SUPERFAMILY SSF89796 4 410 3.92E-118 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_05800 bd0cbc89f4ddeb779374ceb6c4915353 410 Pfam PF02515 CoA-transferase family III 6 386 4.6E-104 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_05800 bd0cbc89f4ddeb779374ceb6c4915353 410 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 2 410 62.889 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 A4R43_05800 bd0cbc89f4ddeb779374ceb6c4915353 410 Gene3D G3DSA:3.30.1540.10 244 338 3.6E-143 T 14-10-2018 A4R43_14705 120cbd70e92c66bd3fec83efb30913be 170 SUPERFAMILY SSF159234 4 167 1.16E-46 T 14-10-2018 IPR035930 FomD-like superfamily A4R43_14705 120cbd70e92c66bd3fec83efb30913be 170 Pfam PF04167 Protein of unknown function (DUF402) 52 119 6.7E-14 T 14-10-2018 IPR007295 Domain of unknown function DUF402 A4R43_14705 120cbd70e92c66bd3fec83efb30913be 170 Gene3D G3DSA:2.40.380.10 1 163 9.1E-66 T 14-10-2018 IPR035930 FomD-like superfamily A4R43_14705 120cbd70e92c66bd3fec83efb30913be 170 PIRSF PIRSF012622 1 170 1.3E-59 T 14-10-2018 IPR014465 Uncharacterised conserved protein UCP012622 A4R43_20635 d956ccd4d1c8ddc766963b6fbcafc130 250 Pfam PF08241 Methyltransferase domain 95 190 1.1E-18 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_20635 d956ccd4d1c8ddc766963b6fbcafc130 250 SUPERFAMILY SSF53335 55 239 1.14E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_20635 d956ccd4d1c8ddc766963b6fbcafc130 250 Gene3D G3DSA:3.40.50.150 43 245 2.8E-36 T 14-10-2018 A4R43_01640 6b80e2a760e31e9d42f37db2ab7c17e7 291 Gene3D G3DSA:3.40.630.30 1 142 1.0E-11 T 14-10-2018 A4R43_01640 6b80e2a760e31e9d42f37db2ab7c17e7 291 SUPERFAMILY SSF55729 17 259 6.62E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_01640 6b80e2a760e31e9d42f37db2ab7c17e7 291 Pfam PF00583 Acetyltransferase (GNAT) family 30 108 3.1E-5 T 14-10-2018 IPR000182 GNAT domain A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 SUPERFAMILY SSF51735 5 239 5.55E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.7E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 7.7E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 7.7E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 7.7E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 7.7E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 7.7E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 Gene3D G3DSA:3.40.50.720 2 239 9.7E-54 T 14-10-2018 A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 3.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 3.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_23985 e948023794b23e9f8334e288e667d6b0 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 238 3.2E-39 T 14-10-2018 A4R43_04800 da1f75458b53ffe9df80cf7a1ced2e4b 167 Gene3D G3DSA:3.40.50.1950 7 157 8.2E-11 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A4R43_04800 da1f75458b53ffe9df80cf7a1ced2e4b 167 SUPERFAMILY SSF52507 12 148 9.55E-11 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A4R43_04800 da1f75458b53ffe9df80cf7a1ced2e4b 167 Pfam PF02441 Flavoprotein 12 108 1.4E-6 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4R43_03490 a8c2b4082753540989906696a17eee94 192 Gene3D G3DSA:3.40.430.10 1 190 1.6E-33 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_03490 a8c2b4082753540989906696a17eee94 192 Pfam PF01872 RibD C-terminal domain 3 177 2.0E-9 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_03490 a8c2b4082753540989906696a17eee94 192 SUPERFAMILY SSF53597 3 191 4.32E-19 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_13945 b013173005ee1ffcdc3f47e5a1132d5f 464 Pfam PF00171 Aldehyde dehydrogenase family 13 459 3.8E-152 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_13945 b013173005ee1ffcdc3f47e5a1132d5f 464 Gene3D G3DSA:3.40.605.10 19 453 2.4E-158 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_13945 b013173005ee1ffcdc3f47e5a1132d5f 464 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_13945 b013173005ee1ffcdc3f47e5a1132d5f 464 Gene3D G3DSA:3.40.309.10 246 428 2.4E-158 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_13945 b013173005ee1ffcdc3f47e5a1132d5f 464 SUPERFAMILY SSF53720 2 463 5.76E-154 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_13945 b013173005ee1ffcdc3f47e5a1132d5f 464 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_00865 5018c970037200957dc7d6171dbcd010 491 SUPERFAMILY SSF81606 27 221 6.54E-6 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_00865 5018c970037200957dc7d6171dbcd010 491 Gene3D G3DSA:3.60.40.10 4 228 6.5E-46 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_00865 5018c970037200957dc7d6171dbcd010 491 Gene3D G3DSA:3.30.565.10 229 374 2.3E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00865 5018c970037200957dc7d6171dbcd010 491 SMART SM00387 264 363 0.001 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_00865 5018c970037200957dc7d6171dbcd010 491 SMART SM00331 9 227 1.1E-21 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_00865 5018c970037200957dc7d6171dbcd010 491 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 38 227 1.2E-32 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_00865 5018c970037200957dc7d6171dbcd010 491 Pfam PF13581 Histidine kinase-like ATPase domain 239 356 2.6E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_00865 5018c970037200957dc7d6171dbcd010 491 Gene3D G3DSA:3.30.750.24 383 487 2.0E-11 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_00865 5018c970037200957dc7d6171dbcd010 491 SUPERFAMILY SSF55874 257 358 5.63E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_00865 5018c970037200957dc7d6171dbcd010 491 SUPERFAMILY SSF52091 400 466 7.26E-7 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_22055 9edebdfbe81a1d846e4718748539e787 445 Pfam PF03109 ABC1 family 121 236 1.1E-33 T 14-10-2018 IPR004147 UbiB domain A4R43_22055 9edebdfbe81a1d846e4718748539e787 445 SUPERFAMILY SSF56112 104 317 2.25E-29 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_22055 9edebdfbe81a1d846e4718748539e787 445 Gene3D G3DSA:1.10.510.10 252 318 1.9E-5 T 14-10-2018 A4R43_22055 9edebdfbe81a1d846e4718748539e787 445 Gene3D G3DSA:3.30.200.20 201 251 1.9E-5 T 14-10-2018 A4R43_35190 205af6861e253b88c91902df9225aadd 153 Pfam PF13577 SnoaL-like domain 5 135 1.4E-23 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_35190 205af6861e253b88c91902df9225aadd 153 Gene3D G3DSA:3.10.450.50 1 153 4.2E-39 T 14-10-2018 A4R43_35190 205af6861e253b88c91902df9225aadd 153 SUPERFAMILY SSF54427 4 142 7.36E-24 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_34170 e421b3f3f65e0c84ca119c2e84ab3a55 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 287 6.7E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_34170 e421b3f3f65e0c84ca119c2e84ab3a55 291 Gene3D G3DSA:1.10.3720.10 49 287 1.7E-54 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_34170 e421b3f3f65e0c84ca119c2e84ab3a55 291 SUPERFAMILY SSF161098 53 276 1.96E-47 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_27360 f696d0796f5e67a5a991061b1dc9e908 325 PIRSF PIRSF016838 1 324 3.2E-21 T 14-10-2018 IPR028349 Protein PafC A4R43_27360 f696d0796f5e67a5a991061b1dc9e908 325 Pfam PF13280 WYL domain 141 318 2.4E-44 T 14-10-2018 IPR026881 WYL domain A4R43_27360 f696d0796f5e67a5a991061b1dc9e908 325 Gene3D G3DSA:1.10.10.10 1 62 4.7E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27360 f696d0796f5e67a5a991061b1dc9e908 325 SUPERFAMILY SSF46785 3 59 1.03E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_27360 f696d0796f5e67a5a991061b1dc9e908 325 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_27360 f696d0796f5e67a5a991061b1dc9e908 325 Pfam PF08279 HTH domain 8 58 6.1E-10 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_20760 89ad177b8254194fb1b32692d88e26be 345 Pfam PF00534 Glycosyl transferases group 1 162 322 6.5E-28 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_20760 89ad177b8254194fb1b32692d88e26be 345 SUPERFAMILY SSF53756 15 345 9.94E-53 T 14-10-2018 A4R43_20760 89ad177b8254194fb1b32692d88e26be 345 Gene3D G3DSA:3.40.50.2000 80 340 5.2E-40 T 14-10-2018 A4R43_20760 89ad177b8254194fb1b32692d88e26be 345 Gene3D G3DSA:3.40.50.2000 151 325 5.2E-40 T 14-10-2018 A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 Gene3D G3DSA:3.30.450.40 3 180 1.3E-17 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 SUPERFAMILY SSF52172 161 233 2.83E-10 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 Pfam PF03861 ANTAR domain 182 233 1.8E-21 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 SMART SM01012 179 234 2.5E-23 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 PIRSF PIRSF036625 2 241 9.0E-48 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 SMART SM00065 30 177 1.9E-4 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 Gene3D G3DSA:1.10.10.10 181 240 7.8E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 Pfam PF13185 GAF domain 34 158 3.5E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_36835 19bff3c4573cb42076013fc3e3960092 242 SUPERFAMILY SSF55781 33 173 2.4E-17 T 14-10-2018 A4R43_00765 eeb834d6dfafd9aa2b1aeac220dc2ee4 147 Gene3D G3DSA:3.10.180.10 1 124 4.1E-13 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_00765 eeb834d6dfafd9aa2b1aeac220dc2ee4 147 SUPERFAMILY SSF54593 3 143 1.97E-11 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_00765 eeb834d6dfafd9aa2b1aeac220dc2ee4 147 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 109 1.6E-11 T 14-10-2018 A4R43_08090 83feff021d6aa89849703939ad6423e8 185 SUPERFAMILY SSF55729 8 173 6.13E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_08090 83feff021d6aa89849703939ad6423e8 185 Gene3D G3DSA:3.40.630.30 8 174 2.7E-41 T 14-10-2018 A4R43_08090 83feff021d6aa89849703939ad6423e8 185 Pfam PF13302 Acetyltransferase (GNAT) domain 11 149 1.0E-18 T 14-10-2018 IPR000182 GNAT domain A4R43_38645 9e20d77422642aed346f87bc34e1eed1 203 Gene3D G3DSA:3.40.50.150 4 185 4.8E-27 T 14-10-2018 A4R43_38645 9e20d77422642aed346f87bc34e1eed1 203 Pfam PF08241 Methyltransferase domain 40 129 2.0E-18 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_38645 9e20d77422642aed346f87bc34e1eed1 203 SUPERFAMILY SSF53335 24 191 2.05E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_10895 3d68f6a163537abb4cf43a896665dc19 507 Gene3D G3DSA:1.20.1720.10 17 233 5.4E-43 T 14-10-2018 A4R43_10895 3d68f6a163537abb4cf43a896665dc19 507 SUPERFAMILY SSF103473 10 503 6.67E-59 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_10895 3d68f6a163537abb4cf43a896665dc19 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 2.7E-8 T 14-10-2018 A4R43_10895 3d68f6a163537abb4cf43a896665dc19 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 363 383 2.7E-8 T 14-10-2018 A4R43_10895 3d68f6a163537abb4cf43a896665dc19 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 2.7E-8 T 14-10-2018 A4R43_10895 3d68f6a163537abb4cf43a896665dc19 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 80 102 2.7E-8 T 14-10-2018 A4R43_10895 3d68f6a163537abb4cf43a896665dc19 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 405 424 2.7E-8 T 14-10-2018 A4R43_10895 3d68f6a163537abb4cf43a896665dc19 507 Pfam PF07690 Major Facilitator Superfamily 22 414 1.4E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 SMART SM01008 20 124 5.5E-30 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 Gene3D G3DSA:3.90.1170.50 1 123 5.9E-26 T 14-10-2018 A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 Gene3D G3DSA:3.30.365.10 411 506 1.2E-22 T 14-10-2018 A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 515 613 6.4E-20 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 139 505 1.0E-92 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 Gene3D G3DSA:3.30.365.10 141 363 3.0E-67 T 14-10-2018 A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 SUPERFAMILY SSF54665 5 130 8.37E-31 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 20 123 6.9E-20 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 Gene3D G3DSA:3.30.365.10 530 670 4.3E-49 T 14-10-2018 A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 Gene3D G3DSA:3.30.365.10 165 258 3.0E-67 T 14-10-2018 A4R43_06280 3d8b7ad27241c8326c5baffd343579ba 681 SUPERFAMILY SSF56003 139 675 2.88E-159 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4R43_06565 3709572e76cd803da11914426443f09b 160 Gene3D G3DSA:3.30.530.20 1 159 9.2E-44 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_06565 3709572e76cd803da11914426443f09b 160 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 24 156 6.0E-22 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_06565 3709572e76cd803da11914426443f09b 160 SUPERFAMILY SSF55961 12 158 1.83E-42 T 14-10-2018 A4R43_38710 e54640404a9880b942e371c36ad53d3e 282 SUPERFAMILY SSF103481 39 124 1.09E-6 T 14-10-2018 A4R43_38710 e54640404a9880b942e371c36ad53d3e 282 SUPERFAMILY SSF103481 172 270 2.88E-8 T 14-10-2018 A4R43_38710 e54640404a9880b942e371c36ad53d3e 282 Pfam PF00892 EamA-like transporter family 5 104 2.0E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_38710 e54640404a9880b942e371c36ad53d3e 282 Pfam PF00892 EamA-like transporter family 134 263 6.6E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_02450 be18a2179939b2b3087fdb905b9582b2 389 Gene3D G3DSA:3.90.1150.10 273 377 7.3E-31 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_02450 be18a2179939b2b3087fdb905b9582b2 389 SUPERFAMILY SSF53383 18 375 3.94E-69 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_02450 be18a2179939b2b3087fdb905b9582b2 389 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 17 376 3.9E-156 T 14-10-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 A4R43_02450 be18a2179939b2b3087fdb905b9582b2 389 Gene3D G3DSA:3.40.640.10 34 271 6.8E-50 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_02450 be18a2179939b2b3087fdb905b9582b2 389 PIRSF PIRSF000525 8 378 8.9E-61 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4R43_02450 be18a2179939b2b3087fdb905b9582b2 389 Pfam PF00266 Aminotransferase class-V 146 336 2.6E-13 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_08155 4de23b98a63bfad32c2e05be1d762425 71 Gene3D G3DSA:3.90.820.10 1 69 3.2E-31 T 14-10-2018 A4R43_08155 4de23b98a63bfad32c2e05be1d762425 71 SUPERFAMILY SSF160582 3 65 4.71E-27 T 14-10-2018 IPR038020 MbtH-like domain superfamily A4R43_08155 4de23b98a63bfad32c2e05be1d762425 71 Pfam PF03621 MbtH-like protein 3 50 7.9E-23 T 14-10-2018 IPR005153 MbtH-like domain A4R43_08155 4de23b98a63bfad32c2e05be1d762425 71 SMART SM00923 1 50 8.9E-22 T 14-10-2018 IPR005153 MbtH-like domain A4R43_26415 ead002b80050c7b8a9267e420893f674 420 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 4 417 1.3E-212 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 A4R43_26415 ead002b80050c7b8a9267e420893f674 420 PIRSF PIRSF006444 1 419 3.4E-201 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 A4R43_26415 ead002b80050c7b8a9267e420893f674 420 Gene3D G3DSA:3.40.50.12780 1 315 7.6E-134 T 14-10-2018 A4R43_26415 ead002b80050c7b8a9267e420893f674 420 SUPERFAMILY SSF56801 11 413 6.41E-64 T 14-10-2018 A4R43_26415 ead002b80050c7b8a9267e420893f674 420 Pfam PF00501 AMP-binding enzyme 72 277 6.0E-13 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_26415 ead002b80050c7b8a9267e420893f674 420 Gene3D G3DSA:3.30.300.30 316 419 1.6E-31 T 14-10-2018 A4R43_26415 ead002b80050c7b8a9267e420893f674 420 Pfam PF14535 AMP-binding enzyme C-terminal domain 324 417 5.1E-27 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal A4R43_19940 a544192f6fdf40a0779a1921fb699d5e 257 Pfam PF10370 Domain of unknown function (DUF2437) 2 54 1.4E-16 T 14-10-2018 IPR018833 Domain of unknown function DUF2437 A4R43_19940 a544192f6fdf40a0779a1921fb699d5e 257 Gene3D G3DSA:3.90.850.10 55 256 1.9E-83 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_19940 a544192f6fdf40a0779a1921fb699d5e 257 Gene3D G3DSA:2.30.30.370 1 54 2.9E-28 T 14-10-2018 A4R43_19940 a544192f6fdf40a0779a1921fb699d5e 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 59 255 1.2E-64 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_19940 a544192f6fdf40a0779a1921fb699d5e 257 SUPERFAMILY SSF56529 51 255 1.23E-75 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_09385 929a3d3bf6d031d74d91ea0fccb39bb7 412 Gene3D G3DSA:1.20.1250.20 9 398 3.8E-23 T 14-10-2018 A4R43_09385 929a3d3bf6d031d74d91ea0fccb39bb7 412 Pfam PF05977 Transmembrane secretion effector 8 399 4.8E-15 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_09385 929a3d3bf6d031d74d91ea0fccb39bb7 412 SUPERFAMILY SSF103473 10 402 1.57E-28 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 SUPERFAMILY SSF158472 239 289 2.88E-8 T 14-10-2018 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 SUPERFAMILY SSF55874 356 530 8.77E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 SMART SM00304 239 291 4.8E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 462 5.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 476 5.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 520 5.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 501 5.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 SUPERFAMILY SSF47384 283 366 2.16E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 Pfam PF00672 HAMP domain 239 288 5.4E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 Gene3D G3DSA:3.30.565.10 371 523 1.1E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 SMART SM00388 299 366 3.7E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 Pfam PF00512 His Kinase A (phospho-acceptor) domain 300 366 3.5E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 413 522 8.5E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 Gene3D G3DSA:1.10.287.130 243 366 1.1E-30 T 14-10-2018 A4R43_23225 554c9dba60f9f1f999db2b8d7c6cdaa5 570 SMART SM00387 412 523 2.1E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_17880 12461a5654b8b77d317fd1f524e123be 316 SUPERFAMILY SSF51735 13 234 1.48E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_17880 12461a5654b8b77d317fd1f524e123be 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_17880 12461a5654b8b77d317fd1f524e123be 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 6.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_17880 12461a5654b8b77d317fd1f524e123be 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 6.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_17880 12461a5654b8b77d317fd1f524e123be 316 Pfam PF00106 short chain dehydrogenase 16 219 4.6E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_17880 12461a5654b8b77d317fd1f524e123be 316 Gene3D G3DSA:3.40.50.720 1 313 1.2E-72 T 14-10-2018 A4R43_12900 bd30926741964c7fa40bf30f97f8f01c 211 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 12 191 6.9E-29 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_12900 bd30926741964c7fa40bf30f97f8f01c 211 SUPERFAMILY SSF109854 2 127 1.95E-17 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_12900 bd30926741964c7fa40bf30f97f8f01c 211 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 101 3.8E-9 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_12900 bd30926741964c7fa40bf30f97f8f01c 211 Gene3D G3DSA:1.20.120.450 2 125 5.2E-8 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_38795 89aade5ac9c8748458b3febc9bfe4805 670 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 384 628 1.7E-90 T 14-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related A4R43_38795 89aade5ac9c8748458b3febc9bfe4805 670 Pfam PF05425 Copper resistance protein D 236 332 2.0E-19 T 14-10-2018 IPR008457 Copper resistance protein D GO:0016021 A4R43_01665 79e90029680e16bb70a5ae46e5529ff5 416 Gene3D G3DSA:1.20.1250.20 218 400 1.1E-16 T 14-10-2018 A4R43_01665 79e90029680e16bb70a5ae46e5529ff5 416 Gene3D G3DSA:1.20.1250.20 5 194 2.8E-31 T 14-10-2018 A4R43_01665 79e90029680e16bb70a5ae46e5529ff5 416 Pfam PF07690 Major Facilitator Superfamily 15 326 2.8E-30 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_01665 79e90029680e16bb70a5ae46e5529ff5 416 SUPERFAMILY SSF103473 5 397 1.44E-60 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18640 73cbfc3c7977417b68784e6131955ba8 164 Pfam PF13302 Acetyltransferase (GNAT) domain 3 132 5.8E-17 T 14-10-2018 IPR000182 GNAT domain A4R43_18640 73cbfc3c7977417b68784e6131955ba8 164 Gene3D G3DSA:3.40.630.30 1 163 1.5E-38 T 14-10-2018 A4R43_18640 73cbfc3c7977417b68784e6131955ba8 164 SUPERFAMILY SSF55729 1 160 9.37E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_25815 b2bb8fa2fa738a37c9303c413a0a44c6 263 Pfam PF11228 Protein of unknown function (DUF3027) 37 227 1.5E-81 T 14-10-2018 IPR021391 Protein of unknown function DUF3027 A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 SUPERFAMILY SSF46785 16 87 1.1E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 2.2E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 SMART SM00895 93 215 8.8E-25 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 Gene3D G3DSA:1.10.10.10 6 84 3.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 Gene3D G3DSA:1.20.120.530 86 228 1.3E-31 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 Pfam PF07729 FCD domain 93 214 2.5E-29 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 7.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 7.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 SMART SM00345 25 83 2.7E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_05830 534788093b46a5cdb5d1c916024c32d2 250 SUPERFAMILY SSF48008 90 222 3.14E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 Pfam PF13191 AAA ATPase domain 2 155 1.0E-15 T 14-10-2018 A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 Gene3D G3DSA:1.10.10.10 781 891 7.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 SMART SM00421 830 887 8.3E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 Pfam PF00196 Bacterial regulatory proteins, luxR family 833 886 1.2E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 833 847 9.6E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 847 863 9.6E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 863 875 9.6E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 SUPERFAMILY SSF46894 828 887 1.05E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_20820 c7bfb18408c4f7edd2d1a8e9f142a714 892 SUPERFAMILY SSF52540 3 254 4.49E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35645 9efa4d929c1e977708bde9737fe3bb69 397 Pfam PF07690 Major Facilitator Superfamily 25 267 2.6E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_35645 9efa4d929c1e977708bde9737fe3bb69 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 88 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_35645 9efa4d929c1e977708bde9737fe3bb69 397 Gene3D G3DSA:1.20.1250.20 11 393 9.8E-51 T 14-10-2018 A4R43_35645 9efa4d929c1e977708bde9737fe3bb69 397 SUPERFAMILY SSF103473 15 393 4.19E-56 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_11125 897fc5d64936fe7ee44c4d76068b2686 142 Pfam PF02308 MgtC family 14 132 3.0E-36 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A4R43_11125 897fc5d64936fe7ee44c4d76068b2686 142 PRINTS PR01837 MgtC/SapB protein signature 13 32 3.5E-45 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A4R43_11125 897fc5d64936fe7ee44c4d76068b2686 142 PRINTS PR01837 MgtC/SapB protein signature 61 83 3.5E-45 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A4R43_11125 897fc5d64936fe7ee44c4d76068b2686 142 PRINTS PR01837 MgtC/SapB protein signature 32 50 3.5E-45 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A4R43_11125 897fc5d64936fe7ee44c4d76068b2686 142 PRINTS PR01837 MgtC/SapB protein signature 88 112 3.5E-45 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A4R43_09325 5146634cda81601a898fd67419a8ad07 138 SUPERFAMILY SSF54427 4 136 8.79E-26 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_09325 5146634cda81601a898fd67419a8ad07 138 Gene3D G3DSA:3.10.450.50 3 138 2.4E-30 T 14-10-2018 A4R43_09325 5146634cda81601a898fd67419a8ad07 138 Pfam PF12680 SnoaL-like domain 6 120 5.8E-16 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_14795 5d6fbb33d663abe2e4e5f04f4e7d944e 281 Pfam PF13649 Methyltransferase domain 82 174 2.7E-19 T 14-10-2018 A4R43_14795 5d6fbb33d663abe2e4e5f04f4e7d944e 281 Gene3D G3DSA:3.40.50.150 71 278 2.6E-38 T 14-10-2018 A4R43_14795 5d6fbb33d663abe2e4e5f04f4e7d944e 281 SUPERFAMILY SSF53335 37 280 1.13E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_02180 2433745b401a8e78331c56516f0e7661 324 Pfam PF00487 Fatty acid desaturase 42 295 8.8E-32 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_25785 37594747247a19fdef093b2af8326a6e 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 3.4E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_25785 37594747247a19fdef093b2af8326a6e 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 3.4E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_25785 37594747247a19fdef093b2af8326a6e 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 3.4E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_25785 37594747247a19fdef093b2af8326a6e 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 3.4E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_25785 37594747247a19fdef093b2af8326a6e 143 Gene3D G3DSA:1.10.10.10 8 142 1.2E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25785 37594747247a19fdef093b2af8326a6e 143 Pfam PF01047 MarR family 34 91 6.5E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_25785 37594747247a19fdef093b2af8326a6e 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_25785 37594747247a19fdef093b2af8326a6e 143 SUPERFAMILY SSF46785 6 138 6.17E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_25785 37594747247a19fdef093b2af8326a6e 143 SMART SM00347 27 127 6.6E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_19305 d664d6d41bcb9f4c1b508968c213b278 286 Gene3D G3DSA:3.40.50.300 23 205 4.6E-28 T 14-10-2018 A4R43_19305 d664d6d41bcb9f4c1b508968c213b278 286 SUPERFAMILY SSF52540 31 251 1.9E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19305 d664d6d41bcb9f4c1b508968c213b278 286 SMART SM00382 35 214 9.4E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_19305 d664d6d41bcb9f4c1b508968c213b278 286 Pfam PF07728 AAA domain (dynein-related subfamily) 40 187 3.5E-12 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A4R43_18710 24b6592d883c3a7534fda1af3c8847e0 33 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 10 33 2.2E-11 T 14-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 A4R43_18710 24b6592d883c3a7534fda1af3c8847e0 33 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 10 33 2.2E-11 T 14-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 A4R43_06125 ee87b8140873387201da7e8327f886ca 244 Gene3D G3DSA:3.40.50.880 14 241 5.1E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_06125 ee87b8140873387201da7e8327f886ca 244 Pfam PF01965 DJ-1/PfpI family 26 184 1.6E-12 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_06125 ee87b8140873387201da7e8327f886ca 244 SUPERFAMILY SSF52317 25 203 2.42E-30 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_22225 2a77c8ee17b4d8d64e79235626a48f29 384 SUPERFAMILY SSF53649 46 381 4.14E-51 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A4R43_22225 2a77c8ee17b4d8d64e79235626a48f29 384 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 48 368 1.8E-32 T 14-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A4R43_22225 2a77c8ee17b4d8d64e79235626a48f29 384 Gene3D G3DSA:3.40.720.10 42 383 4.3E-40 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A4R43_29550 7ade9c02cad6ad1d11f771533a2ed01f 270 Gene3D G3DSA:3.90.1200.10 69 264 4.5E-8 T 14-10-2018 A4R43_29550 7ade9c02cad6ad1d11f771533a2ed01f 270 Pfam PF01636 Phosphotransferase enzyme family 14 214 5.3E-19 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_29550 7ade9c02cad6ad1d11f771533a2ed01f 270 SUPERFAMILY SSF56112 3 240 3.5E-31 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_24245 351f4eb46b14662a67326a704f028501 793 Gene3D G3DSA:1.20.1580.10 108 373 3.6E-157 T 14-10-2018 A4R43_24245 351f4eb46b14662a67326a704f028501 793 Gene3D G3DSA:3.40.50.300 22 474 3.6E-157 T 14-10-2018 A4R43_24245 351f4eb46b14662a67326a704f028501 793 Pfam PF00005 ABC transporter 504 711 5.0E-13 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_24245 351f4eb46b14662a67326a704f028501 793 Gene3D G3DSA:1.10.8.280 187 295 3.6E-157 T 14-10-2018 A4R43_24245 351f4eb46b14662a67326a704f028501 793 Gene3D G3DSA:3.40.50.300 498 787 4.7E-102 T 14-10-2018 A4R43_24245 351f4eb46b14662a67326a704f028501 793 SUPERFAMILY SSF52540 21 456 4.12E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24245 351f4eb46b14662a67326a704f028501 793 Gene3D G3DSA:1.20.1580.10 580 618 4.7E-102 T 14-10-2018 A4R43_24245 351f4eb46b14662a67326a704f028501 793 SUPERFAMILY SSF52540 496 764 1.89E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37715 0007a69aff24089169987b22bf5e95f2 396 Pfam PF00266 Aminotransferase class-V 21 390 5.8E-67 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_37715 0007a69aff24089169987b22bf5e95f2 396 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 394 9.0E-143 T 14-10-2018 IPR011340 Cysteine desulfurase-related A4R43_37715 0007a69aff24089169987b22bf5e95f2 396 Gene3D G3DSA:3.90.1150.10 19 394 1.1E-134 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_37715 0007a69aff24089169987b22bf5e95f2 396 Gene3D G3DSA:3.40.640.10 28 282 1.1E-134 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_37715 0007a69aff24089169987b22bf5e95f2 396 SUPERFAMILY SSF53383 3 394 5.31E-87 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 PRINTS PR00364 Disease resistance protein signature 359 373 2.2E-7 T 14-10-2018 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 PRINTS PR00364 Disease resistance protein signature 445 459 2.2E-7 T 14-10-2018 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 PRINTS PR00364 Disease resistance protein signature 281 296 2.2E-7 T 14-10-2018 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SUPERFAMILY SSF46894 2 91 1.02E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Pfam PF03704 Bacterial transcriptional activator domain 98 240 4.6E-42 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 91 8.4E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SUPERFAMILY SSF48452 771 885 5.88E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Pfam PF13374 Tetratricopeptide repeat 695 722 0.0044 T 14-10-2018 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SMART SM01043 98 240 4.8E-50 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Gene3D G3DSA:1.25.40.10 803 887 4.0E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Gene3D G3DSA:1.25.40.10 560 802 1.1E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SMART SM00862 15 91 9.7E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SUPERFAMILY SSF48452 94 260 5.42E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Pfam PF00931 NB-ARC domain 280 460 1.7E-6 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Gene3D G3DSA:1.25.40.10 95 258 5.5E-48 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Gene3D G3DSA:1.10.10.10 1 93 6.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SMART SM00028 773 806 2.8 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SMART SM00028 813 846 2.5E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SMART SM00028 733 766 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SMART SM00028 693 726 21.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SMART SM00028 853 886 46.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SUPERFAMILY SSF48452 693 805 2.75E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Pfam PF13424 Tetratricopeptide repeat 813 871 1.0E-7 T 14-10-2018 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 Pfam PF13424 Tetratricopeptide repeat 737 803 3.2E-10 T 14-10-2018 A4R43_03585 a185b7759175bf656cf5caf42b81dfcc 887 SUPERFAMILY SSF52540 254 513 2.56E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_02925 af50558f1b7fdcd567d50e333e1ddf0f 233 SUPERFAMILY SSF88659 88 163 3.36E-7 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_02925 af50558f1b7fdcd567d50e333e1ddf0f 233 Pfam PF13490 Putative zinc-finger 176 209 2.3E-8 T 14-10-2018 IPR027383 Putative zinc-finger A4R43_02925 af50558f1b7fdcd567d50e333e1ddf0f 233 Gene3D G3DSA:1.10.1740.10 3 79 5.7E-5 T 14-10-2018 A4R43_02925 af50558f1b7fdcd567d50e333e1ddf0f 233 SUPERFAMILY SSF88946 4 75 5.89E-5 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_02925 af50558f1b7fdcd567d50e333e1ddf0f 233 Gene3D G3DSA:1.10.10.1320 178 230 1.6E-5 T 14-10-2018 A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 Pfam PF07729 FCD domain 84 201 2.9E-14 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 Gene3D G3DSA:1.20.120.530 76 214 2.5E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 2.4E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 2.4E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 Gene3D G3DSA:1.10.10.10 6 71 4.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 SMART SM00895 80 202 9.1E-11 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 SUPERFAMILY SSF46785 5 74 2.73E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 5.1E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 SUPERFAMILY SSF48008 76 207 3.92E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_02380 da364a8afa716c04b45282c7ec7e13fc 235 SMART SM00345 12 70 1.3E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_19340 9b5ddc32374cfe0c8c048967dbb2ff3d 312 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 3 293 6.7E-90 T 14-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 A4R43_19340 9b5ddc32374cfe0c8c048967dbb2ff3d 312 SUPERFAMILY SSF53613 3 288 2.49E-56 T 14-10-2018 IPR029056 Ribokinase-like A4R43_19340 9b5ddc32374cfe0c8c048967dbb2ff3d 312 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 3 292 1.3E-90 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A4R43_19340 9b5ddc32374cfe0c8c048967dbb2ff3d 312 Gene3D G3DSA:3.40.1190.20 1 300 4.3E-90 T 14-10-2018 IPR029056 Ribokinase-like A4R43_19340 9b5ddc32374cfe0c8c048967dbb2ff3d 312 Pfam PF00294 pfkB family carbohydrate kinase 14 284 2.9E-39 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_19340 9b5ddc32374cfe0c8c048967dbb2ff3d 312 PIRSF PIRSF000535 1 285 5.6E-65 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A4R43_19340 9b5ddc32374cfe0c8c048967dbb2ff3d 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_29055 e980040f261cf539b89f24731186b5a5 332 SUPERFAMILY SSF52151 2 230 2.25E-24 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_29055 e980040f261cf539b89f24731186b5a5 332 Pfam PF01734 Patatin-like phospholipase 2 193 1.4E-13 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A4R43_29055 e980040f261cf539b89f24731186b5a5 332 Gene3D G3DSA:3.40.1090.10 85 239 4.2E-8 T 14-10-2018 A4R43_38560 f02c57573dc5758c83ec514e6fc1cc1a 143 SUPERFAMILY SSF50475 9 139 6.71E-36 T 14-10-2018 A4R43_38560 f02c57573dc5758c83ec514e6fc1cc1a 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 90 4.4E-16 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_38560 f02c57573dc5758c83ec514e6fc1cc1a 143 Gene3D G3DSA:2.30.110.10 7 141 3.8E-45 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_38560 f02c57573dc5758c83ec514e6fc1cc1a 143 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 139 3.0E-44 T 14-10-2018 IPR019920 F420-binding domain, putative A4R43_07890 890d17a2df8a43d5198beca16198f3fa 441 Gene3D G3DSA:3.90.226.10 151 440 2.1E-82 T 14-10-2018 A4R43_07890 890d17a2df8a43d5198beca16198f3fa 441 Gene3D G3DSA:1.20.58.1300 9 150 7.5E-47 T 14-10-2018 A4R43_07890 890d17a2df8a43d5198beca16198f3fa 441 SUPERFAMILY SSF52096 168 432 1.1E-36 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_07890 890d17a2df8a43d5198beca16198f3fa 441 Pfam PF00378 Enoyl-CoA hydratase/isomerase 284 389 1.9E-14 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 SMART SM00345 20 79 1.5E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 SUPERFAMILY SSF53383 89 449 7.09E-78 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 Gene3D G3DSA:3.90.1150.10 95 447 1.2E-77 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 Gene3D G3DSA:1.10.10.10 11 82 4.7E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 SUPERFAMILY SSF46785 17 83 5.12E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 77 1.5E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.0E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.0E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 Gene3D G3DSA:3.40.640.10 128 347 1.2E-77 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_32615 bf5d4dbd280be861292ba9dedd1867de 465 Pfam PF00155 Aminotransferase class I and II 121 445 1.9E-28 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_16155 a95eef56c674a8b677725e39d6ce0080 148 SUPERFAMILY SSF50475 13 146 1.45E-13 T 14-10-2018 A4R43_16155 a95eef56c674a8b677725e39d6ce0080 148 Gene3D G3DSA:2.30.110.10 8 148 1.9E-23 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 SMART SM00895 94 212 1.4E-18 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 SUPERFAMILY SSF48008 90 213 2.54E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 Pfam PF07729 FCD domain 94 206 1.5E-18 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 Gene3D G3DSA:1.20.120.530 89 212 7.7E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.6E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 8.3E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 8.3E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 Gene3D G3DSA:1.10.10.10 6 82 1.4E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 SUPERFAMILY SSF46785 6 88 7.18E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_18265 29f2c4a08ae503de4b8bb9facf10776c 218 SMART SM00345 15 74 1.1E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_37365 b9791f2c7f39e02a12d9c1bb058455bb 180 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 77 1.1E-9 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_37365 b9791f2c7f39e02a12d9c1bb058455bb 180 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 7 157 3.6E-24 T 14-10-2018 IPR010195 Uncharacterised peroxidase-related A4R43_37365 b9791f2c7f39e02a12d9c1bb058455bb 180 Gene3D G3DSA:1.20.1290.10 41 163 3.1E-36 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_37365 b9791f2c7f39e02a12d9c1bb058455bb 180 SUPERFAMILY SSF69118 5 160 1.28E-38 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_37365 b9791f2c7f39e02a12d9c1bb058455bb 180 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 84 7.7E-9 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 SMART SM00357 3 67 5.4E-31 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 SUPERFAMILY SSF50249 1 66 2.79E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.8E-31 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 Gene3D G3DSA:2.40.50.140 2 66 5.5E-31 T 14-10-2018 A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 PIRSF PIRSF002599 1 67 3.2E-25 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 PRINTS PR00050 Cold shock protein signature 4 19 9.5E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 PRINTS PR00050 Cold shock protein signature 40 58 9.5E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_32425 03111a3f36706e9dfddb2c9556792955 67 PRINTS PR00050 Cold shock protein signature 25 34 9.5E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_20095 6c2246e67b419cbaf1028710153d73c3 348 SMART SM00849 38 254 2.2E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_20095 6c2246e67b419cbaf1028710153d73c3 348 Pfam PF00753 Metallo-beta-lactamase superfamily 39 254 1.1E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_20095 6c2246e67b419cbaf1028710153d73c3 348 Gene3D G3DSA:3.60.15.10 18 281 5.3E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_20095 6c2246e67b419cbaf1028710153d73c3 348 SUPERFAMILY SSF56281 10 345 1.82E-50 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_10965 281f781642a5f944037415b1409e6ab4 256 SUPERFAMILY SSF89082 161 252 1.22E-12 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain A4R43_10965 281f781642a5f944037415b1409e6ab4 256 Gene3D G3DSA:1.10.490.50 161 256 2.5E-21 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain A4R43_10965 281f781642a5f944037415b1409e6ab4 256 Gene3D G3DSA:1.10.1660.10 3 141 5.9E-41 T 14-10-2018 A4R43_10965 281f781642a5f944037415b1409e6ab4 256 SMART SM00422 3 72 8.3E-31 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10965 281f781642a5f944037415b1409e6ab4 256 Pfam PF07739 TipAS antibiotic-recognition domain 132 250 7.4E-25 T 14-10-2018 IPR012925 TipAS antibiotic-recognition domain A4R43_10965 281f781642a5f944037415b1409e6ab4 256 Pfam PF13411 MerR HTH family regulatory protein 5 70 1.7E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10965 281f781642a5f944037415b1409e6ab4 256 SUPERFAMILY SSF46955 4 106 2.42E-30 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_10965 281f781642a5f944037415b1409e6ab4 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.2E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10965 281f781642a5f944037415b1409e6ab4 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.2E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10965 281f781642a5f944037415b1409e6ab4 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.2E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10965 281f781642a5f944037415b1409e6ab4 256 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 2.4E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 SMART SM00448 2 115 1.2E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 Pfam PF00072 Response regulator receiver domain 4 113 1.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 SUPERFAMILY SSF52172 1 129 3.13E-29 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_33685 1c0710f640033e1c5c26be1027790375 201 Gene3D G3DSA:3.40.50.12740 2 201 8.7E-54 T 14-10-2018 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 SMART SM00421 138 195 3.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 SUPERFAMILY SSF46894 130 201 1.12E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.2E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.2E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33685 1c0710f640033e1c5c26be1027790375 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.2E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 Gene3D G3DSA:3.30.70.1450 143 215 1.1E-7 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 Pfam PF02254 TrkA-N domain 3 116 2.9E-23 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 SUPERFAMILY SSF51735 2 140 3.66E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 Gene3D G3DSA:3.40.50.720 1 130 2.8E-30 T 14-10-2018 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 SUPERFAMILY SSF116726 143 210 2.88E-7 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 Pfam PF02080 TrkA-C domain 154 212 2.6E-9 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 9.3E-7 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 9.3E-7 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 9.3E-7 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4R43_14015 6a9876c099ccd5e725cf5b1830362403 221 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 9.3E-7 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4R43_38495 640f993f1ddb15797c7565244925a529 384 SUPERFAMILY SSF51569 4 381 9.52E-136 T 14-10-2018 A4R43_38495 640f993f1ddb15797c7565244925a529 384 Gene3D G3DSA:3.20.20.70 36 384 1.4E-136 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_38495 640f993f1ddb15797c7565244925a529 384 Pfam PF01474 Class-II DAHP synthetase family 6 173 1.5E-48 T 14-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4R43_38495 640f993f1ddb15797c7565244925a529 384 Pfam PF01474 Class-II DAHP synthetase family 178 379 1.0E-80 T 14-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4R43_30125 e36abf5b45607994cd3b5a94bb025ebc 439 Pfam PF02470 MlaD protein 47 127 5.1E-9 T 14-10-2018 IPR003399 Mce/MlaD A4R43_15695 69b2e603f1fcbc479e19daf3cc10d90d 490 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 208 9.7E-17 T 14-10-2018 A4R43_15695 69b2e603f1fcbc479e19daf3cc10d90d 490 SUPERFAMILY SSF51905 3 226 8.42E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_15695 69b2e603f1fcbc479e19daf3cc10d90d 490 Gene3D G3DSA:3.50.50.60 309 487 2.1E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_15695 69b2e603f1fcbc479e19daf3cc10d90d 490 SUPERFAMILY SSF51905 268 483 2.14E-17 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_15695 69b2e603f1fcbc479e19daf3cc10d90d 490 Gene3D G3DSA:3.50.50.60 2 169 3.5E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_15695 69b2e603f1fcbc479e19daf3cc10d90d 490 PRINTS PR00419 Adrenodoxin reductase family signature 173 187 4.7E-5 T 14-10-2018 A4R43_15695 69b2e603f1fcbc479e19daf3cc10d90d 490 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 4.7E-5 T 14-10-2018 A4R43_15695 69b2e603f1fcbc479e19daf3cc10d90d 490 PRINTS PR00419 Adrenodoxin reductase family signature 224 237 4.7E-5 T 14-10-2018 A4R43_14870 869b68c31796912e36c6208114d5fe0d 261 SUPERFAMILY SSF53474 17 256 1.62E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14870 869b68c31796912e36c6208114d5fe0d 261 Gene3D G3DSA:3.40.50.1820 13 260 3.4E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14870 869b68c31796912e36c6208114d5fe0d 261 Pfam PF00326 Prolyl oligopeptidase family 95 244 7.3E-8 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_12520 aa5eef9867c05d217c2f55ae8ab02301 470 Pfam PF04389 Peptidase family M28 232 445 2.6E-33 T 14-10-2018 IPR007484 Peptidase M28 A4R43_12520 aa5eef9867c05d217c2f55ae8ab02301 470 Gene3D G3DSA:3.50.30.30 100 223 2.0E-58 T 14-10-2018 A4R43_12520 aa5eef9867c05d217c2f55ae8ab02301 470 SUPERFAMILY SSF53187 214 455 1.63E-44 T 14-10-2018 A4R43_12520 aa5eef9867c05d217c2f55ae8ab02301 470 SUPERFAMILY SSF52025 115 214 5.49E-6 T 14-10-2018 A4R43_12520 aa5eef9867c05d217c2f55ae8ab02301 470 Pfam PF02225 PA domain 128 212 4.6E-8 T 14-10-2018 IPR003137 PA domain A4R43_12520 aa5eef9867c05d217c2f55ae8ab02301 470 Gene3D G3DSA:3.40.630.10 61 446 2.0E-58 T 14-10-2018 A4R43_00595 8797e13ba5e8444992a5ae4c8a2aa6d7 225 Gene3D G3DSA:3.30.530.20 56 222 1.2E-21 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_00595 8797e13ba5e8444992a5ae4c8a2aa6d7 225 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 74 221 4.7E-13 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_00595 8797e13ba5e8444992a5ae4c8a2aa6d7 225 SUPERFAMILY SSF55961 72 222 5.5E-24 T 14-10-2018 A4R43_17385 894eb46477d6a872fd81134c8551fbb1 316 Pfam PF12833 Helix-turn-helix domain 233 311 2.3E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_17385 894eb46477d6a872fd81134c8551fbb1 316 SMART SM00342 227 310 2.1E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_17385 894eb46477d6a872fd81134c8551fbb1 316 SUPERFAMILY SSF46689 264 313 1.72E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17385 894eb46477d6a872fd81134c8551fbb1 316 SUPERFAMILY SSF46689 213 260 1.08E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_17385 894eb46477d6a872fd81134c8551fbb1 316 Gene3D G3DSA:3.40.50.880 2 205 8.8E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_17385 894eb46477d6a872fd81134c8551fbb1 316 Gene3D G3DSA:1.10.10.60 211 314 9.7E-27 T 14-10-2018 A4R43_17385 894eb46477d6a872fd81134c8551fbb1 316 Pfam PF01965 DJ-1/PfpI family 3 171 2.3E-14 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_17385 894eb46477d6a872fd81134c8551fbb1 316 SUPERFAMILY SSF52317 3 193 3.67E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_32135 8e7f47fb1bb32119529e0e9a399374f0 414 Gene3D G3DSA:3.50.50.60 113 402 2.5E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_32135 8e7f47fb1bb32119529e0e9a399374f0 414 Gene3D G3DSA:3.50.50.60 8 88 1.4E-15 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_32135 8e7f47fb1bb32119529e0e9a399374f0 414 Pfam PF01266 FAD dependent oxidoreductase 10 397 3.5E-55 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_32135 8e7f47fb1bb32119529e0e9a399374f0 414 SUPERFAMILY SSF51971 9 401 1.88E-40 T 14-10-2018 A4R43_32135 8e7f47fb1bb32119529e0e9a399374f0 414 Gene3D G3DSA:3.30.9.10 139 359 2.5E-38 T 14-10-2018 A4R43_32135 8e7f47fb1bb32119529e0e9a399374f0 414 SUPERFAMILY SSF54373 273 360 6.02E-9 T 14-10-2018 A4R43_24225 744bf92410080d77f8a32ff2cee08c85 269 Gene3D G3DSA:3.10.450.50 131 265 1.0E-32 T 14-10-2018 A4R43_24225 744bf92410080d77f8a32ff2cee08c85 269 Gene3D G3DSA:3.10.450.50 1 130 3.4E-32 T 14-10-2018 A4R43_24225 744bf92410080d77f8a32ff2cee08c85 269 SUPERFAMILY SSF54427 3 123 7.45E-24 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_24225 744bf92410080d77f8a32ff2cee08c85 269 SUPERFAMILY SSF54427 133 254 1.38E-25 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_24225 744bf92410080d77f8a32ff2cee08c85 269 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 3 123 5.8E-9 T 14-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 A4R43_24225 744bf92410080d77f8a32ff2cee08c85 269 Pfam PF13474 SnoaL-like domain 134 254 2.7E-19 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_24225 744bf92410080d77f8a32ff2cee08c85 269 Pfam PF13474 SnoaL-like domain 7 126 6.2E-19 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_20975 14ce322045ce9bd5a509d66d57aa2e2f 70 Pfam PF02805 Metal binding domain of Ada 9 60 5.8E-6 T 14-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A4R43_20975 14ce322045ce9bd5a509d66d57aa2e2f 70 Gene3D G3DSA:3.40.10.10 6 63 5.4E-7 T 14-10-2018 IPR035451 Ada-like domain superfamily A4R43_20975 14ce322045ce9bd5a509d66d57aa2e2f 70 SUPERFAMILY SSF57884 7 67 2.22E-13 T 14-10-2018 IPR035451 Ada-like domain superfamily A4R43_28555 7c18521262c22e7f96113ccdcba073d1 262 Gene3D G3DSA:3.20.180.10 168 255 1.3E-15 T 14-10-2018 IPR037119 Haem oxygenase HugZ-like superfamily A4R43_28555 7c18521262c22e7f96113ccdcba073d1 262 Pfam PF10615 Protein of unknown function (DUF2470) 178 245 1.6E-7 T 14-10-2018 IPR019595 Domain of unknown function DUF2470 A4R43_28555 7c18521262c22e7f96113ccdcba073d1 262 SUPERFAMILY SSF50475 44 259 1.26E-18 T 14-10-2018 A4R43_27440 cff603b96adce71d479c8b16d09fe2a1 143 SUPERFAMILY SSF50475 3 139 2.62E-23 T 14-10-2018 A4R43_27440 cff603b96adce71d479c8b16d09fe2a1 143 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 137 3.0E-25 T 14-10-2018 IPR019920 F420-binding domain, putative A4R43_27440 cff603b96adce71d479c8b16d09fe2a1 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 90 5.1E-12 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_27440 cff603b96adce71d479c8b16d09fe2a1 143 Gene3D G3DSA:2.30.110.10 1 139 8.1E-26 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_17010 ebd628bddae6566d3998408cc707d799 173 Gene3D G3DSA:3.90.960.10 5 172 3.8E-36 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4R43_17010 ebd628bddae6566d3998408cc707d799 173 SUPERFAMILY SSF55826 14 159 6.93E-30 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4R43_17010 ebd628bddae6566d3998408cc707d799 173 Pfam PF04073 Aminoacyl-tRNA editing domain 34 154 2.3E-26 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4R43_12545 d2d5432b3de78b00b4b60dfc80dd195d 177 SUPERFAMILY SSF46689 1 60 5.64E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_12545 d2d5432b3de78b00b4b60dfc80dd195d 177 Gene3D G3DSA:1.10.357.10 1 176 2.6E-29 T 14-10-2018 A4R43_12545 d2d5432b3de78b00b4b60dfc80dd195d 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 46 4.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_12545 d2d5432b3de78b00b4b60dfc80dd195d 177 SUPERFAMILY SSF48498 69 174 1.22E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_39095 1bcb1a0c05120ae6abdaa988d905366a 207 Pfam PF13508 Acetyltransferase (GNAT) domain 122 176 2.0E-8 T 14-10-2018 IPR000182 GNAT domain A4R43_39095 1bcb1a0c05120ae6abdaa988d905366a 207 SUPERFAMILY SSF55729 3 197 3.04E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_39095 1bcb1a0c05120ae6abdaa988d905366a 207 Gene3D G3DSA:3.40.630.30 4 202 2.1E-37 T 14-10-2018 A4R43_25465 26d11242d60c1e93ff815e2ae19feb7b 574 TIGRFAM TIGR03767 P_acnes_RR: metallophosphoesterase, PPA1498 family 62 571 8.7E-208 T 14-10-2018 IPR022506 Metallophosphoesterase, PPA1498 A4R43_25465 26d11242d60c1e93ff815e2ae19feb7b 574 Pfam PF00149 Calcineurin-like phosphoesterase 95 469 3.5E-4 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_25465 26d11242d60c1e93ff815e2ae19feb7b 574 SUPERFAMILY SSF56300 95 509 9.18E-28 T 14-10-2018 A4R43_40455 cdf084ed2bd37c23fe34cd4f2b7e8d18 493 SUPERFAMILY SSF53822 121 481 6.39E-17 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_40455 cdf084ed2bd37c23fe34cd4f2b7e8d18 493 Gene3D G3DSA:3.40.50.2300 225 370 3.4E-14 T 14-10-2018 A4R43_40455 cdf084ed2bd37c23fe34cd4f2b7e8d18 493 Gene3D G3DSA:3.40.50.2300 121 462 3.4E-14 T 14-10-2018 A4R43_30690 4eec670c036e4b911e30bc0131736533 259 SUPERFAMILY SSF53213 4 258 1.18E-81 T 14-10-2018 A4R43_30690 4eec670c036e4b911e30bc0131736533 259 Gene3D G3DSA:3.40.830.10 1 259 9.5E-77 T 14-10-2018 A4R43_30690 4eec670c036e4b911e30bc0131736533 259 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 239 1.4E-41 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A4R43_30690 4eec670c036e4b911e30bc0131736533 259 PIRSF PIRSF006157 1 259 4.3E-84 T 14-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 A4R43_08895 ab6abfae83c8cc0b3a48a16ced8bb9de 251 SUPERFAMILY SSF52266 3 190 2.29E-38 T 14-10-2018 A4R43_08895 ab6abfae83c8cc0b3a48a16ced8bb9de 251 Gene3D G3DSA:3.40.50.1110 2 193 1.7E-29 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_08895 ab6abfae83c8cc0b3a48a16ced8bb9de 251 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 180 5.9E-27 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 5.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 5.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 5.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 Gene3D G3DSA:3.40.50.12740 2 200 2.4E-51 T 14-10-2018 A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 SMART SM00421 138 195 6.8E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 SUPERFAMILY SSF52172 2 128 2.42E-25 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 195 3.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 SMART SM00448 2 115 3.4E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 Pfam PF00072 Response regulator receiver domain 4 115 3.0E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_37045 c39129cfb2ecd2f21e780c1969d6dfd1 201 SUPERFAMILY SSF46894 129 201 1.94E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_30290 99cdb46bc723c960f62d355f84b855dd 636 Pfam PF01935 Domain of unknown function DUF87 253 316 7.7E-7 T 14-10-2018 IPR002789 Helicase HerA, central domain A4R43_30290 99cdb46bc723c960f62d355f84b855dd 636 Gene3D G3DSA:3.40.50.300 239 576 2.0E-75 T 14-10-2018 A4R43_30290 99cdb46bc723c960f62d355f84b855dd 636 Gene3D G3DSA:1.10.8.730 309 434 2.0E-75 T 14-10-2018 A4R43_30290 99cdb46bc723c960f62d355f84b855dd 636 SUPERFAMILY SSF52540 210 585 1.43E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05525 81f848ad0a3c2d06bcbe0b2989560aea 452 SUPERFAMILY SSF53067 237 448 1.4E-36 T 14-10-2018 A4R43_05525 81f848ad0a3c2d06bcbe0b2989560aea 452 SUPERFAMILY SSF53067 5 231 3.43E-41 T 14-10-2018 A4R43_05525 81f848ad0a3c2d06bcbe0b2989560aea 452 Gene3D G3DSA:3.30.420.40 2 222 7.1E-77 T 14-10-2018 A4R43_05525 81f848ad0a3c2d06bcbe0b2989560aea 452 Gene3D G3DSA:3.30.420.40 223 452 1.8E-92 T 14-10-2018 A4R43_05525 81f848ad0a3c2d06bcbe0b2989560aea 452 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 210 7.5E-23 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4R43_05525 81f848ad0a3c2d06bcbe0b2989560aea 452 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 239 425 2.6E-30 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4R43_10390 eec7e5688f269d01ff3a63bd8274cca8 253 Gene3D G3DSA:3.30.450.40 77 253 1.3E-46 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_10390 eec7e5688f269d01ff3a63bd8274cca8 253 SUPERFAMILY SSF46785 5 78 1.12E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_10390 eec7e5688f269d01ff3a63bd8274cca8 253 SMART SM00346 5 95 2.5E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_10390 eec7e5688f269d01ff3a63bd8274cca8 253 Gene3D G3DSA:1.10.10.10 1 76 3.7E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10390 eec7e5688f269d01ff3a63bd8274cca8 253 Pfam PF09339 IclR helix-turn-helix domain 7 55 7.5E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_10390 eec7e5688f269d01ff3a63bd8274cca8 253 SUPERFAMILY SSF55781 70 252 1.11E-39 T 14-10-2018 A4R43_10390 eec7e5688f269d01ff3a63bd8274cca8 253 Pfam PF01614 Bacterial transcriptional regulator 123 248 3.7E-26 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_02770 640ef15b853245bcf91fbe06699fc18b 274 SUPERFAMILY SSF117396 1 250 2.09E-59 T 14-10-2018 IPR036520 UPF0759 superfamily A4R43_02770 640ef15b853245bcf91fbe06699fc18b 274 Pfam PF01904 Protein of unknown function DUF72 13 249 2.7E-51 T 14-10-2018 IPR002763 Protein of unknown function DUF72 A4R43_02770 640ef15b853245bcf91fbe06699fc18b 274 Gene3D G3DSA:3.20.20.410 1 253 4.0E-38 T 14-10-2018 IPR036520 UPF0759 superfamily A4R43_18330 bbac9ed90b53ecdab4cc610fb58fe6af 409 SUPERFAMILY SSF50156 100 216 3.25E-12 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 A4R43_18330 bbac9ed90b53ecdab4cc610fb58fe6af 409 Pfam PF02163 Peptidase family M50 11 358 1.2E-48 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A4R43_18330 bbac9ed90b53ecdab4cc610fb58fe6af 409 Gene3D G3DSA:2.30.42.10 158 247 1.5E-10 T 14-10-2018 A4R43_32445 27bc8b05686ba76684f8359ae629342d 322 SUPERFAMILY SSF53850 5 309 2.04E-52 T 14-10-2018 A4R43_32445 27bc8b05686ba76684f8359ae629342d 322 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 88 308 2.4E-47 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_32445 27bc8b05686ba76684f8359ae629342d 322 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 111 124 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site A4R43_32445 27bc8b05686ba76684f8359ae629342d 322 Gene3D G3DSA:3.40.190.10 180 268 5.8E-72 T 14-10-2018 A4R43_32445 27bc8b05686ba76684f8359ae629342d 322 SMART SM00062 87 310 1.8E-54 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_32445 27bc8b05686ba76684f8359ae629342d 322 Gene3D G3DSA:3.40.190.10 76 311 5.8E-72 T 14-10-2018 A4R43_29915 96a76ef24b1d57a3df6d6d34a9934d1b 201 Pfam PF12696 TraM recognition site of TraD and TraG 47 125 1.5E-5 T 14-10-2018 IPR032689 TraD/TraG, TraM recognition site A4R43_29915 96a76ef24b1d57a3df6d6d34a9934d1b 201 Gene3D G3DSA:3.40.50.300 4 148 1.5E-15 T 14-10-2018 A4R43_29915 96a76ef24b1d57a3df6d6d34a9934d1b 201 SUPERFAMILY SSF52540 8 138 6.37E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10245 3b48b029dc2d297ec1fbb7d347eea0de 233 SUPERFAMILY SSF46955 121 225 4.49E-15 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_10245 3b48b029dc2d297ec1fbb7d347eea0de 233 Gene3D G3DSA:1.10.1660.10 5 109 1.8E-12 T 14-10-2018 A4R43_10245 3b48b029dc2d297ec1fbb7d347eea0de 233 SUPERFAMILY SSF46955 5 104 2.84E-10 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_10245 3b48b029dc2d297ec1fbb7d347eea0de 233 Pfam PF00376 MerR family regulatory protein 7 42 1.1E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10245 3b48b029dc2d297ec1fbb7d347eea0de 233 Pfam PF13411 MerR HTH family regulatory protein 121 189 1.3E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10245 3b48b029dc2d297ec1fbb7d347eea0de 233 SMART SM00422 4 72 2.9E-4 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10245 3b48b029dc2d297ec1fbb7d347eea0de 233 SMART SM00422 121 191 1.3E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_10245 3b48b029dc2d297ec1fbb7d347eea0de 233 Gene3D G3DSA:1.10.1660.10 115 232 6.4E-18 T 14-10-2018 A4R43_07695 6246b707b16b7751946f77ba42678190 344 Gene3D G3DSA:3.40.50.720 157 310 4.3E-109 T 14-10-2018 A4R43_07695 6246b707b16b7751946f77ba42678190 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 140 4.6E-24 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_07695 6246b707b16b7751946f77ba42678190 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_07695 6246b707b16b7751946f77ba42678190 344 Pfam PF00107 Zinc-binding dehydrogenase 183 302 4.2E-15 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_07695 6246b707b16b7751946f77ba42678190 344 SUPERFAMILY SSF50129 2 188 4.39E-44 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_07695 6246b707b16b7751946f77ba42678190 344 SUPERFAMILY SSF51735 146 308 5.42E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07695 6246b707b16b7751946f77ba42678190 344 Gene3D G3DSA:3.90.180.10 15 338 4.3E-109 T 14-10-2018 A4R43_07695 6246b707b16b7751946f77ba42678190 344 SMART SM00829 13 338 5.0E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_08845 70dd802cdf9f8d15077d5ecf5f2b7708 424 Gene3D G3DSA:1.10.1740.10 2 81 4.5E-9 T 14-10-2018 A4R43_08845 70dd802cdf9f8d15077d5ecf5f2b7708 424 SUPERFAMILY SSF88946 7 97 4.32E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08845 70dd802cdf9f8d15077d5ecf5f2b7708 424 Pfam PF04542 Sigma-70 region 2 20 79 1.0E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08845 70dd802cdf9f8d15077d5ecf5f2b7708 424 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 35 66 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_08845 70dd802cdf9f8d15077d5ecf5f2b7708 424 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 171 3.3E-15 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_08845 70dd802cdf9f8d15077d5ecf5f2b7708 424 SUPERFAMILY SSF88659 110 171 2.24E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_08845 70dd802cdf9f8d15077d5ecf5f2b7708 424 Gene3D G3DSA:1.10.10.10 125 173 2.0E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08845 70dd802cdf9f8d15077d5ecf5f2b7708 424 Pfam PF08281 Sigma-70, region 4 121 169 3.3E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_32305 a0ce0a717d6c4b693d5d6eccb20b70ca 204 Gene3D G3DSA:1.10.357.10 54 193 3.0E-27 T 14-10-2018 A4R43_32305 a0ce0a717d6c4b693d5d6eccb20b70ca 204 SUPERFAMILY SSF46689 9 76 1.49E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_32305 a0ce0a717d6c4b693d5d6eccb20b70ca 204 SUPERFAMILY SSF48498 84 193 1.26E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_32305 a0ce0a717d6c4b693d5d6eccb20b70ca 204 Gene3D G3DSA:1.10.10.60 1 53 1.5E-23 T 14-10-2018 A4R43_32305 a0ce0a717d6c4b693d5d6eccb20b70ca 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 SUPERFAMILY SSF54897 46 117 1.36E-13 T 14-10-2018 A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 Pfam PF05922 Peptidase inhibitor I9 49 116 2.8E-7 T 14-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 SUPERFAMILY SSF52743 126 386 1.22E-81 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 Gene3D G3DSA:3.40.50.200 119 393 1.4E-95 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 PRINTS PR00723 Subtilisin serine protease family (S8) signature 148 167 6.1E-19 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 199 6.1E-19 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 PRINTS PR00723 Subtilisin serine protease family (S8) signature 337 353 6.1E-19 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 Pfam PF00082 Subtilase family 149 375 4.6E-39 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 Gene3D G3DSA:3.30.70.80 39 116 1.2E-19 T 14-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 190 200 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A4R43_27985 89f4ec4cdf32e2c9a6bf33885c01c5ef 393 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 338 348 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A4R43_37805 08425c2a8089934e8b9c3b4d4201ccc7 517 Pfam PF09423 PhoD-like phosphatase 160 483 1.6E-94 T 14-10-2018 IPR018946 Alkaline phosphatase D-related A4R43_37805 08425c2a8089934e8b9c3b4d4201ccc7 517 SUPERFAMILY SSF56300 156 487 2.18E-25 T 14-10-2018 A4R43_37805 08425c2a8089934e8b9c3b4d4201ccc7 517 Gene3D G3DSA:2.60.40.380 39 148 6.2E-38 T 14-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 A4R43_37805 08425c2a8089934e8b9c3b4d4201ccc7 517 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 47 145 9.0E-32 T 14-10-2018 IPR032093 Phospholipase D, N-terminal A4R43_37805 08425c2a8089934e8b9c3b4d4201ccc7 517 Gene3D G3DSA:3.60.21.70 149 517 3.6E-115 T 14-10-2018 IPR038607 PhoD-like superfamily A4R43_39285 0bd9be276c461123ab3f09eae54f275f 428 SUPERFAMILY SSF55874 341 423 6.81E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39285 0bd9be276c461123ab3f09eae54f275f 428 Pfam PF07730 Histidine kinase 237 303 3.1E-14 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_39285 0bd9be276c461123ab3f09eae54f275f 428 SMART SM00387 336 426 8.5E-4 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_39285 0bd9be276c461123ab3f09eae54f275f 428 Gene3D G3DSA:3.30.565.10 302 424 6.3E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39285 0bd9be276c461123ab3f09eae54f275f 428 Pfam PF13796 Putative sensor 74 215 1.1E-20 T 14-10-2018 IPR025828 Putative sensor domain A4R43_29930 b0cb54e1e427e2b9a790c7424ee72405 299 PRINTS PR00412 Epoxide hydrolase signature 37 55 5.5E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_29930 b0cb54e1e427e2b9a790c7424ee72405 299 PRINTS PR00412 Epoxide hydrolase signature 224 240 5.5E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_29930 b0cb54e1e427e2b9a790c7424ee72405 299 PRINTS PR00412 Epoxide hydrolase signature 57 72 5.5E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_29930 b0cb54e1e427e2b9a790c7424ee72405 299 PRINTS PR00412 Epoxide hydrolase signature 257 279 5.5E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_29930 b0cb54e1e427e2b9a790c7424ee72405 299 Gene3D G3DSA:3.40.50.1820 1 281 1.6E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_29930 b0cb54e1e427e2b9a790c7424ee72405 299 Pfam PF12146 Serine aminopeptidase, S33 28 267 1.7E-19 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 A4R43_29930 b0cb54e1e427e2b9a790c7424ee72405 299 SUPERFAMILY SSF53474 13 281 3.13E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 Pfam PF01494 FAD binding domain 5 343 1.2E-75 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 Gene3D G3DSA:3.50.50.60 5 352 2.8E-165 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 SUPERFAMILY SSF54373 176 276 1.26E-37 T 14-10-2018 A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 SUPERFAMILY SSF51905 4 388 4.15E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.7E-26 T 14-10-2018 A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.7E-26 T 14-10-2018 A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.7E-26 T 14-10-2018 A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.7E-26 T 14-10-2018 A4R43_00060 68c93c66cd1b59c6c0d49f947b3d325d 392 Gene3D G3DSA:3.30.9.10 75 386 2.8E-165 T 14-10-2018 A4R43_19870 d4218f2732f69e06182dd2312b90bba5 133 Gene3D G3DSA:3.30.1330.40 3 133 4.5E-28 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_19870 d4218f2732f69e06182dd2312b90bba5 133 SUPERFAMILY SSF55298 29 132 4.4E-24 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_19870 d4218f2732f69e06182dd2312b90bba5 133 Pfam PF01042 Endoribonuclease L-PSP 28 132 1.4E-17 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4R43_27905 b6febbace4211ce529d72f0dd8843197 125 SUPERFAMILY SSF54197 4 124 2.38E-20 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_27905 b6febbace4211ce529d72f0dd8843197 125 Gene3D G3DSA:3.30.428.10 5 124 8.6E-18 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_27905 b6febbace4211ce529d72f0dd8843197 125 Pfam PF01230 HIT domain 23 89 1.9E-5 T 14-10-2018 IPR001310 Histidine triad (HIT) protein A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 Gene3D G3DSA:3.40.50.1820 7 291 5.9E-78 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 PRINTS PR00412 Epoxide hydrolase signature 268 290 5.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 PRINTS PR00412 Epoxide hydrolase signature 35 53 5.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 PRINTS PR00412 Epoxide hydrolase signature 101 114 5.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 SUPERFAMILY SSF53474 4 291 2.46E-66 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 3.9E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 3.9E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 3.9E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16735 c0136b54f252277c7f8deb9a91d0038e 292 Pfam PF00561 alpha/beta hydrolase fold 29 130 4.0E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16165 e36983cc01dc13ab6c8cc71ab2e9f635 207 SUPERFAMILY SSF52540 20 192 1.46E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16165 e36983cc01dc13ab6c8cc71ab2e9f635 207 Pfam PF03029 Conserved hypothetical ATP binding protein 24 191 2.7E-26 T 14-10-2018 IPR004130 GPN-loop GTPase A4R43_16165 e36983cc01dc13ab6c8cc71ab2e9f635 207 Gene3D G3DSA:3.40.50.300 15 196 6.0E-19 T 14-10-2018 A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 Gene3D G3DSA:3.30.9.30 35 278 3.0E-79 T 14-10-2018 A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 2.2E-19 T 14-10-2018 A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 2.2E-19 T 14-10-2018 A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 2.2E-19 T 14-10-2018 A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.2E-19 T 14-10-2018 A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 Gene3D G3DSA:3.50.50.60 4 349 3.0E-79 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 SUPERFAMILY SSF51905 2 369 3.02E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 Pfam PF01494 FAD binding domain 144 347 8.6E-12 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_07945 040246fa4c581eecc6fa79c6210965c7 395 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 35 3.3E-5 T 14-10-2018 A4R43_31910 51b87b925ffed6531e7684c7b3f8ca43 265 Gene3D G3DSA:3.40.50.150 1 265 7.5E-97 T 14-10-2018 A4R43_31910 51b87b925ffed6531e7684c7b3f8ca43 265 Pfam PF04672 S-adenosyl methyltransferase 3 264 8.9E-83 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_31910 51b87b925ffed6531e7684c7b3f8ca43 265 SUPERFAMILY SSF53335 7 250 1.51E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_31910 51b87b925ffed6531e7684c7b3f8ca43 265 PIRSF PIRSF017393 1 265 2.9E-89 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_36270 67dc1e8f61ca60ba42d28c8991588537 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36270 67dc1e8f61ca60ba42d28c8991588537 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36270 67dc1e8f61ca60ba42d28c8991588537 181 Pfam PF13305 WHG domain 83 160 4.3E-14 T 14-10-2018 IPR025996 WHG domain A4R43_36270 67dc1e8f61ca60ba42d28c8991588537 181 Gene3D G3DSA:1.10.357.10 1 179 8.8E-39 T 14-10-2018 A4R43_36270 67dc1e8f61ca60ba42d28c8991588537 181 SUPERFAMILY SSF46689 4 77 9.23E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_36270 67dc1e8f61ca60ba42d28c8991588537 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.7E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36270 67dc1e8f61ca60ba42d28c8991588537 181 SUPERFAMILY SSF48498 83 170 4.45E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_14750 616a62afc4248b34c60988824248cc36 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 5.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14750 616a62afc4248b34c60988824248cc36 211 Pfam PF13305 WHG domain 93 172 1.0E-13 T 14-10-2018 IPR025996 WHG domain A4R43_14750 616a62afc4248b34c60988824248cc36 211 SUPERFAMILY SSF48498 89 175 7.19E-18 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_14750 616a62afc4248b34c60988824248cc36 211 Gene3D G3DSA:1.10.357.10 3 180 3.0E-36 T 14-10-2018 A4R43_14750 616a62afc4248b34c60988824248cc36 211 SUPERFAMILY SSF46689 8 84 3.18E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_02940 234564f19bb85e2f5d94a913ce6942d2 139 Pfam PF12802 MarR family 30 87 6.1E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_02940 234564f19bb85e2f5d94a913ce6942d2 139 SUPERFAMILY SSF46785 6 135 1.72E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02940 234564f19bb85e2f5d94a913ce6942d2 139 SMART SM00347 25 123 1.1E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_02940 234564f19bb85e2f5d94a913ce6942d2 139 Gene3D G3DSA:1.10.10.10 3 137 8.9E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26805 77085e4a07010865c534bee97e3ea6d9 124 Gene3D G3DSA:3.30.1130.10 1 119 1.2E-44 T 14-10-2018 A4R43_26805 77085e4a07010865c534bee97e3ea6d9 124 TIGRFAM TIGR00526 folB_dom: FolB domain 3 120 7.9E-35 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4R43_26805 77085e4a07010865c534bee97e3ea6d9 124 SMART SM00905 5 117 6.5E-50 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4R43_26805 77085e4a07010865c534bee97e3ea6d9 124 Pfam PF02152 Dihydroneopterin aldolase 5 116 1.5E-34 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4R43_26805 77085e4a07010865c534bee97e3ea6d9 124 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 7.6E-40 T 14-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4R43_26805 77085e4a07010865c534bee97e3ea6d9 124 SUPERFAMILY SSF55620 3 119 1.06E-35 T 14-10-2018 A4R43_23860 f07cd26c440e46d09764c5ca761f6cbc 279 Gene3D G3DSA:3.40.50.150 4 277 2.2E-90 T 14-10-2018 A4R43_23860 f07cd26c440e46d09764c5ca761f6cbc 279 SUPERFAMILY SSF53335 19 259 8.32E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_23860 f07cd26c440e46d09764c5ca761f6cbc 279 Pfam PF04672 S-adenosyl methyltransferase 14 276 8.0E-75 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_23860 f07cd26c440e46d09764c5ca761f6cbc 279 PIRSF PIRSF017393 3 277 3.2E-76 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_19830 981062406796d605357c632d62f2478e 253 Pfam PF01061 ABC-2 type transporter 10 216 1.4E-22 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_19830 981062406796d605357c632d62f2478e 253 PIRSF PIRSF006648 2 253 3.4E-66 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_27100 d879b748ff923d361554cc1e1b835fdc 154 Gene3D G3DSA:3.30.300.20 1 149 2.0E-50 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_27100 d879b748ff923d361554cc1e1b835fdc 154 Pfam PF02566 OsmC-like protein 50 147 7.6E-14 T 14-10-2018 IPR003718 OsmC/Ohr family A4R43_27100 d879b748ff923d361554cc1e1b835fdc 154 SUPERFAMILY SSF82784 3 150 5.1E-43 T 14-10-2018 IPR036102 OsmC/Ohr superfamily A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 SUPERFAMILY SSF52540 737 1098 5.28E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 Pfam PF13087 AAA domain 922 1095 6.1E-20 T 14-10-2018 A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 SUPERFAMILY SSF53098 393 487 2.45E-5 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 3 484 3.4E-60 T 14-10-2018 IPR019993 RecB family nuclease, TM0106, putative A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 Gene3D G3DSA:3.40.50.300 729 911 1.9E-28 T 14-10-2018 A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 Pfam PF13604 AAA domain 745 896 3.8E-13 T 14-10-2018 A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 Pfam PF13482 RNase_H superfamily 299 484 3.9E-20 T 14-10-2018 IPR038720 YprB, ribonuclease H-like domain A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 SMART SM00382 743 1084 2.0E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 Pfam PF12705 PD-(D/E)XK nuclease superfamily 76 207 2.2E-4 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A4R43_12180 76ca5a540d557b5ae2432bf0c366907c 1128 Gene3D G3DSA:3.40.50.300 929 1113 3.1E-32 T 14-10-2018 A4R43_07245 8638bc71dd1c2fea7bc49aa7d664a3ff 413 Gene3D G3DSA:1.10.1740.10 10 85 1.8E-6 T 14-10-2018 A4R43_07245 8638bc71dd1c2fea7bc49aa7d664a3ff 413 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 168 2.3E-12 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_07245 8638bc71dd1c2fea7bc49aa7d664a3ff 413 Pfam PF08281 Sigma-70, region 4 114 165 4.0E-9 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_07245 8638bc71dd1c2fea7bc49aa7d664a3ff 413 SUPERFAMILY SSF88946 10 91 7.06E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_07245 8638bc71dd1c2fea7bc49aa7d664a3ff 413 Gene3D G3DSA:1.10.10.10 108 169 9.1E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07245 8638bc71dd1c2fea7bc49aa7d664a3ff 413 Pfam PF04542 Sigma-70 region 2 23 81 9.1E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_07245 8638bc71dd1c2fea7bc49aa7d664a3ff 413 SUPERFAMILY SSF88659 105 167 4.11E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_38900 8d10337af7b57b7d6b79eddce255a2fb 244 Gene3D G3DSA:3.60.15.10 3 212 5.5E-42 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_38900 8d10337af7b57b7d6b79eddce255a2fb 244 SMART SM00849 21 190 2.3E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_38900 8d10337af7b57b7d6b79eddce255a2fb 244 SUPERFAMILY SSF56281 4 209 1.76E-43 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_38900 8d10337af7b57b7d6b79eddce255a2fb 244 Pfam PF00753 Metallo-beta-lactamase superfamily 24 190 2.2E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 242 5.1E-65 T 14-10-2018 A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 SUPERFAMILY SSF51735 6 243 3.96E-81 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 Gene3D G3DSA:3.40.50.720 1 243 6.8E-84 T 14-10-2018 A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 183 6.0E-7 T 14-10-2018 A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.2E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.2E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.2E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.2E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28230 8cc249c81d2b26fe96ae406b3c0b1de4 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_13660 ef4aec04f52da5d8d8cab98ded09876d 540 Gene3D G3DSA:3.40.50.300 3 286 3.0E-45 T 14-10-2018 A4R43_13660 ef4aec04f52da5d8d8cab98ded09876d 540 Pfam PF00005 ABC transporter 346 476 2.8E-9 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_13660 ef4aec04f52da5d8d8cab98ded09876d 540 Pfam PF00005 ABC transporter 21 191 1.1E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_13660 ef4aec04f52da5d8d8cab98ded09876d 540 SUPERFAMILY SSF52540 336 525 1.29E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13660 ef4aec04f52da5d8d8cab98ded09876d 540 SMART SM00382 352 521 4.7E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_13660 ef4aec04f52da5d8d8cab98ded09876d 540 SMART SM00382 29 236 2.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_13660 ef4aec04f52da5d8d8cab98ded09876d 540 Gene3D G3DSA:3.40.50.300 314 533 9.7E-32 T 14-10-2018 A4R43_13660 ef4aec04f52da5d8d8cab98ded09876d 540 SUPERFAMILY SSF52540 4 249 3.42E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_03725 05f5fd118694433391b45b8624777073 410 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 79 90 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_03725 05f5fd118694433391b45b8624777073 410 Gene3D G3DSA:3.30.70.20 23 137 1.5E-5 T 14-10-2018 A4R43_03725 05f5fd118694433391b45b8624777073 410 SUPERFAMILY SSF46548 34 97 2.35E-8 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_03725 05f5fd118694433391b45b8624777073 410 Pfam PF02754 Cysteine-rich domain 291 372 6.4E-10 T 14-10-2018 IPR004017 Cysteine-rich domain A4R43_03725 05f5fd118694433391b45b8624777073 410 Pfam PF02754 Cysteine-rich domain 179 244 1.1E-8 T 14-10-2018 IPR004017 Cysteine-rich domain A4R43_03725 05f5fd118694433391b45b8624777073 410 Pfam PF13534 4Fe-4S dicluster domain 27 93 6.6E-6 T 14-10-2018 A4R43_18040 c3571133bf96e0aba437f574feea5309 536 Pfam PF02652 L-lactate permease 14 525 2.6E-136 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 A4R43_18040 c3571133bf96e0aba437f574feea5309 536 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 14 527 2.5E-133 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 A4R43_28125 cddb9e12f0d9409ce6a8404a4092e6b6 145 Pfam PF04138 GtrA-like protein 24 141 3.7E-19 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4R43_32750 1fef72221d34197a0df3c24d233bece1 415 SUPERFAMILY SSF53756 16 401 4.89E-79 T 14-10-2018 A4R43_32750 1fef72221d34197a0df3c24d233bece1 415 Gene3D G3DSA:3.40.50.2000 2 399 1.8E-125 T 14-10-2018 A4R43_32750 1fef72221d34197a0df3c24d233bece1 415 Pfam PF00534 Glycosyl transferases group 1 206 379 2.6E-32 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_32750 1fef72221d34197a0df3c24d233bece1 415 Gene3D G3DSA:3.40.50.2000 194 383 1.8E-125 T 14-10-2018 A4R43_32750 1fef72221d34197a0df3c24d233bece1 415 Pfam PF13439 Glycosyltransferase Family 4 17 198 8.3E-30 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_32750 1fef72221d34197a0df3c24d233bece1 415 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 1 403 4.5E-193 T 14-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 A4R43_32750 1fef72221d34197a0df3c24d233bece1 415 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 1 407 50.314 T 14-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 A4R43_04015 318b4cd0d74a6de9c3cadb8cedb7f948 464 Pfam PF01566 Natural resistance-associated macrophage protein 53 399 2.2E-18 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_04015 318b4cd0d74a6de9c3cadb8cedb7f948 464 Gene3D G3DSA:1.20.1740.10 270 463 3.0E-6 T 14-10-2018 A4R43_07285 3c33339e6155ecb89a28f4a4c8cc2605 295 Pfam PF00005 ABC transporter 22 158 1.2E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_07285 3c33339e6155ecb89a28f4a4c8cc2605 295 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_07285 3c33339e6155ecb89a28f4a4c8cc2605 295 SMART SM00382 30 216 1.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_07285 3c33339e6155ecb89a28f4a4c8cc2605 295 Gene3D G3DSA:3.40.50.300 1 223 1.8E-61 T 14-10-2018 A4R43_07285 3c33339e6155ecb89a28f4a4c8cc2605 295 SUPERFAMILY SSF52540 4 219 2.01E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10030 8b12ab8957ddb4a4f3bd04555ca0b9ae 440 Gene3D G3DSA:1.20.1250.20 17 438 1.2E-65 T 14-10-2018 A4R43_10030 8b12ab8957ddb4a4f3bd04555ca0b9ae 440 Pfam PF07690 Major Facilitator Superfamily 64 372 1.7E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_10030 8b12ab8957ddb4a4f3bd04555ca0b9ae 440 SUPERFAMILY SSF103473 16 434 1.19E-68 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_33845 d0db4128785e27b1a9e21558822128f4 229 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 208 33.011 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33845 d0db4128785e27b1a9e21558822128f4 229 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 1.5E-70 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33845 d0db4128785e27b1a9e21558822128f4 229 SUPERFAMILY SSF52166 1 204 1.7E-73 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_33845 d0db4128785e27b1a9e21558822128f4 229 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 6.8E-64 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A4R43_33845 d0db4128785e27b1a9e21558822128f4 229 Gene3D G3DSA:3.40.1370.10 1 207 3.8E-73 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_09595 bf8f6d4c869a9023ecd1fb89acc5e7aa 173 SUPERFAMILY SSF51735 40 136 3.05E-20 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09595 bf8f6d4c869a9023ecd1fb89acc5e7aa 173 Gene3D G3DSA:3.40.50.720 34 164 1.2E-23 T 14-10-2018 A4R43_09595 bf8f6d4c869a9023ecd1fb89acc5e7aa 173 Pfam PF00106 short chain dehydrogenase 41 125 5.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28130 b8975b4040fbf38c80f0bd5061832bb6 433 Gene3D G3DSA:3.30.43.10 9 44 5.6E-29 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_28130 b8975b4040fbf38c80f0bd5061832bb6 433 Gene3D G3DSA:3.30.465.10 45 173 5.6E-29 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_28130 b8975b4040fbf38c80f0bd5061832bb6 433 Gene3D G3DSA:3.40.462.10 174 190 5.6E-29 T 14-10-2018 IPR016170 Cytokinin dehydrogenase, C-terminal domain superfamily KEGG: 00908+1.5.99.12 A4R43_28130 b8975b4040fbf38c80f0bd5061832bb6 433 SUPERFAMILY SSF56176 14 161 7.36E-39 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_28130 b8975b4040fbf38c80f0bd5061832bb6 433 Pfam PF04030 D-arabinono-1,4-lactone oxidase 371 430 1.8E-8 T 14-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 A4R43_28130 b8975b4040fbf38c80f0bd5061832bb6 433 Pfam PF01565 FAD binding domain 11 132 9.1E-29 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_37605 4995276a91e33b408dc039406f13197f 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.3E-6 T 14-10-2018 A4R43_37605 4995276a91e33b408dc039406f13197f 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 4.3E-6 T 14-10-2018 A4R43_37605 4995276a91e33b408dc039406f13197f 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 4.3E-6 T 14-10-2018 A4R43_37605 4995276a91e33b408dc039406f13197f 435 SUPERFAMILY SSF51905 3 338 1.81E-30 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37605 4995276a91e33b408dc039406f13197f 435 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 328 1.7E-58 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_37605 4995276a91e33b408dc039406f13197f 435 Gene3D G3DSA:3.50.50.100 1 399 1.7E-110 T 14-10-2018 A4R43_37605 4995276a91e33b408dc039406f13197f 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.5E-12 T 14-10-2018 A4R43_37605 4995276a91e33b408dc039406f13197f 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 1.5E-12 T 14-10-2018 A4R43_37605 4995276a91e33b408dc039406f13197f 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.5E-12 T 14-10-2018 A4R43_37605 4995276a91e33b408dc039406f13197f 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.5E-12 T 14-10-2018 A4R43_37130 c063b28972e9aff389a0aaf9ae659b1d 139 Pfam PF00960 Neocarzinostatin family 33 138 5.1E-22 T 14-10-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 A4R43_37130 c063b28972e9aff389a0aaf9ae659b1d 139 SUPERFAMILY SSF49319 30 138 3.79E-23 T 14-10-2018 IPR027273 Neocarzinostatin-like A4R43_37130 c063b28972e9aff389a0aaf9ae659b1d 139 Gene3D G3DSA:2.60.40.230 29 139 3.2E-28 T 14-10-2018 A4R43_37130 c063b28972e9aff389a0aaf9ae659b1d 139 PRINTS PR01885 Macromomycin family signature 83 100 3.3E-14 T 14-10-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 A4R43_37130 c063b28972e9aff389a0aaf9ae659b1d 139 PRINTS PR01885 Macromomycin family signature 30 49 3.3E-14 T 14-10-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 A4R43_37130 c063b28972e9aff389a0aaf9ae659b1d 139 PRINTS PR01885 Macromomycin family signature 53 68 3.3E-14 T 14-10-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 A4R43_14860 e279b34ca7c8e138a0a40fb6a420d02a 134 SUPERFAMILY SSF54637 6 131 6.74E-26 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_14860 e279b34ca7c8e138a0a40fb6a420d02a 134 Pfam PF03061 Thioesterase superfamily 42 117 2.1E-13 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_14860 e279b34ca7c8e138a0a40fb6a420d02a 134 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 127 1.3E-24 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A4R43_14860 e279b34ca7c8e138a0a40fb6a420d02a 134 Gene3D G3DSA:3.10.129.10 3 131 7.0E-43 T 14-10-2018 A4R43_04305 f0b6e169667840c52426c6d2db99684e 207 PIRSF PIRSF005639 2 207 6.4E-72 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04305 f0b6e169667840c52426c6d2db99684e 207 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 8 200 1.1E-69 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04305 f0b6e169667840c52426c6d2db99684e 207 Pfam PF01174 SNO glutamine amidotransferase family 10 203 5.4E-57 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04305 f0b6e169667840c52426c6d2db99684e 207 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 8 202 38.532 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04305 f0b6e169667840c52426c6d2db99684e 207 SUPERFAMILY SSF52317 7 203 2.96E-47 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_04305 f0b6e169667840c52426c6d2db99684e 207 ProSitePatterns PS01236 PdxT/SNO family family signature. 45 55 - T 14-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4R43_04305 f0b6e169667840c52426c6d2db99684e 207 Gene3D G3DSA:3.40.50.880 4 207 1.1E-71 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_24150 b8ecd2f09f665bfda2b0b9e4d532fb93 325 SUPERFAMILY SSF51445 30 314 2.69E-54 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_24150 b8ecd2f09f665bfda2b0b9e4d532fb93 325 SMART SM00636 33 306 7.2E-6 T 14-10-2018 IPR011583 Chitinase II GO:0008061 A4R43_24150 b8ecd2f09f665bfda2b0b9e4d532fb93 325 Pfam PF00704 Glycosyl hydrolases family 18 35 306 8.1E-27 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A4R43_24150 b8ecd2f09f665bfda2b0b9e4d532fb93 325 Gene3D G3DSA:3.20.20.80 31 325 9.5E-75 T 14-10-2018 A4R43_40480 fefb11504e06b67fe0b4f54d62669c77 266 SUPERFAMILY SSF51735 3 229 5.76E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40480 fefb11504e06b67fe0b4f54d62669c77 266 Pfam PF00106 short chain dehydrogenase 3 130 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_40480 fefb11504e06b67fe0b4f54d62669c77 266 Gene3D G3DSA:3.40.50.720 2 258 2.1E-34 T 14-10-2018 A4R43_07470 392f8268e1d0900143af3d9556c85973 64 Pfam PF11387 Protein of unknown function (DUF2795) 13 56 2.0E-18 T 14-10-2018 IPR021527 Protein of unknown function DUF2795 A4R43_12460 a9f020afb1e1e3eb324f21c1407c36c3 172 Gene3D G3DSA:2.40.50.140 1 62 3.8E-10 T 14-10-2018 A4R43_12460 a9f020afb1e1e3eb324f21c1407c36c3 172 Pfam PF00313 'Cold-shock' DNA-binding domain 1 60 6.0E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_12460 a9f020afb1e1e3eb324f21c1407c36c3 172 SUPERFAMILY SSF50249 1 61 6.37E-8 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_27400 76a91a52f4aa18a8889d0744faf6d795 309 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 64 2.9E-10 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4R43_27400 76a91a52f4aa18a8889d0744faf6d795 309 Gene3D G3DSA:1.10.3720.10 95 304 1.8E-23 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_27400 76a91a52f4aa18a8889d0744faf6d795 309 SUPERFAMILY SSF161098 99 290 2.35E-27 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_27400 76a91a52f4aa18a8889d0744faf6d795 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 308 7.9E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 Pfam PF00550 Phosphopantetheine attachment site 584 648 1.3E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 Gene3D G3DSA:3.30.300.30 436 561 5.7E-41 T 14-10-2018 A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 SMART SM00823 Phosphopantetheine attachment site 581 652 3.8E-10 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 SUPERFAMILY SSF47336 577 655 1.23E-11 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 SMART SM01294 582 648 8.3E-7 T 14-10-2018 A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 Gene3D G3DSA:3.40.50.12780 1 434 1.8E-146 T 14-10-2018 A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 Gene3D G3DSA:1.10.1200.10 571 654 1.8E-15 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 Pfam PF00501 AMP-binding enzyme 6 442 2.1E-83 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_38620 5d66958c874e7da00f797c7986c1c89e 662 SUPERFAMILY SSF56801 2 547 7.72E-112 T 14-10-2018 A4R43_16205 cf7da242034a6c5a4b796a0d3d3a3ef0 283 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 2 282 15.6 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4R43_16205 cf7da242034a6c5a4b796a0d3d3a3ef0 283 SUPERFAMILY SSF53335 7 274 1.29E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_16205 cf7da242034a6c5a4b796a0d3d3a3ef0 283 Gene3D G3DSA:3.40.50.150 52 282 1.8E-36 T 14-10-2018 A4R43_16205 cf7da242034a6c5a4b796a0d3d3a3ef0 283 Pfam PF01564 Spermine/spermidine synthase domain 58 219 1.0E-13 T 14-10-2018 A4R43_29400 87c131173cccd835ab2b00d28d2ae342 119 Gene3D G3DSA:3.30.750.24 3 118 8.9E-29 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_29400 87c131173cccd835ab2b00d28d2ae342 119 Pfam PF01740 STAS domain 11 113 3.3E-13 T 14-10-2018 IPR002645 STAS domain A4R43_29400 87c131173cccd835ab2b00d28d2ae342 119 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 10 112 1.4E-22 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_29400 87c131173cccd835ab2b00d28d2ae342 119 SUPERFAMILY SSF52091 10 115 1.57E-21 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_20845 6f81c294361d877217b4cfb74a818647 131 Gene3D G3DSA:3.30.565.10 9 131 3.6E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_02950 e719dc517a929871586495bc4d26ece4 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 3.5E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02950 e719dc517a929871586495bc4d26ece4 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.5E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02950 e719dc517a929871586495bc4d26ece4 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.5E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02950 e719dc517a929871586495bc4d26ece4 105 Gene3D G3DSA:1.10.10.10 9 104 7.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02950 e719dc517a929871586495bc4d26ece4 105 SMART SM00418 11 88 9.9E-25 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02950 e719dc517a929871586495bc4d26ece4 105 SUPERFAMILY SSF46785 8 91 9.49E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02950 e719dc517a929871586495bc4d26ece4 105 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 4.9E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 Gene3D G3DSA:3.40.50.720 2 233 3.4E-54 T 14-10-2018 A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 6.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 6.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 6.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 6.2E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 SUPERFAMILY SSF51735 8 232 3.38E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_41805 5bd5493f434e00748ed460cc4ba704d9 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 231 3.2E-41 T 14-10-2018 A4R43_05595 9cc71ab139aed36ffa19ecd7516b0d3f 320 Gene3D G3DSA:2.60.120.10 32 265 1.6E-61 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_05595 9cc71ab139aed36ffa19ecd7516b0d3f 320 Pfam PF05726 Pirin C-terminal cupin domain 193 292 5.8E-20 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 A4R43_05595 9cc71ab139aed36ffa19ecd7516b0d3f 320 SUPERFAMILY SSF51182 35 305 2.25E-68 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_05595 9cc71ab139aed36ffa19ecd7516b0d3f 320 PIRSF PIRSF006232 19 302 5.7E-72 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 A4R43_05595 9cc71ab139aed36ffa19ecd7516b0d3f 320 Pfam PF02678 Pirin 39 141 1.3E-24 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 A4R43_22045 2302f297e76c988757c524a53fd8f088 171 Pfam PF01863 Protein of unknown function DUF45 90 146 2.3E-19 T 14-10-2018 IPR002725 Protein of unknown function DUF45 A4R43_22045 2302f297e76c988757c524a53fd8f088 171 Gene3D G3DSA:3.30.2010.10 76 156 3.2E-13 T 14-10-2018 A4R43_41755 207cfb9a030dcdfb622c2f2d783ed2ab 331 Gene3D G3DSA:3.40.50.970 2 331 4.8E-114 T 14-10-2018 A4R43_41755 207cfb9a030dcdfb622c2f2d783ed2ab 331 SUPERFAMILY SSF52518 13 330 2.24E-92 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_41755 207cfb9a030dcdfb622c2f2d783ed2ab 331 Pfam PF00676 Dehydrogenase E1 component 25 319 5.7E-89 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A4R43_03480 5fbfaf883048840b70845285f9dd8e77 168 SUPERFAMILY SSF50475 23 156 3.04E-27 T 14-10-2018 A4R43_03480 5fbfaf883048840b70845285f9dd8e77 168 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 25 108 2.0E-17 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_03480 5fbfaf883048840b70845285f9dd8e77 168 Gene3D G3DSA:2.30.110.10 21 166 1.8E-35 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_40715 9481d4cd2cc36d19bc39973c345218ff 382 Gene3D G3DSA:2.160.20.10 41 382 9.6E-8 T 14-10-2018 IPR012334 Pectin lyase fold A4R43_40715 9481d4cd2cc36d19bc39973c345218ff 382 SUPERFAMILY SSF51126 88 378 2.69E-13 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_40715 9481d4cd2cc36d19bc39973c345218ff 382 SMART SM00710 291 313 2600.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_40715 9481d4cd2cc36d19bc39973c345218ff 382 SMART SM00710 133 155 1300.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_40715 9481d4cd2cc36d19bc39973c345218ff 382 SMART SM00710 343 372 4000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_40715 9481d4cd2cc36d19bc39973c345218ff 382 SMART SM00710 186 208 92.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_40715 9481d4cd2cc36d19bc39973c345218ff 382 SMART SM00710 209 231 9200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_21940 da6e5be4e61fcfeadb30a5e6e7efc226 232 Pfam PF13796 Putative sensor 23 208 5.9E-37 T 14-10-2018 IPR025828 Putative sensor domain A4R43_21230 333029d5a5f7df5456aa24a24d3abbad 145 Gene3D G3DSA:2.30.110.10 5 142 1.1E-34 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_21230 333029d5a5f7df5456aa24a24d3abbad 145 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 24 89 3.5E-6 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_21230 333029d5a5f7df5456aa24a24d3abbad 145 SUPERFAMILY SSF50475 23 126 4.75E-16 T 14-10-2018 A4R43_20135 6af7e154aad6c3ff26ab39ba4ac71601 260 SUPERFAMILY SSF55729 23 230 1.19E-42 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_20135 6af7e154aad6c3ff26ab39ba4ac71601 260 Pfam PF13444 Acetyltransferase (GNAT) domain 41 142 4.6E-35 T 14-10-2018 A4R43_20135 6af7e154aad6c3ff26ab39ba4ac71601 260 Gene3D G3DSA:3.40.630.30 28 166 1.6E-27 T 14-10-2018 A4R43_00275 387cbe5220e857c04694154ea84f0c96 436 Gene3D G3DSA:3.30.1330.120 260 380 6.2E-58 T 14-10-2018 A4R43_00275 387cbe5220e857c04694154ea84f0c96 436 SUPERFAMILY SSF103378 5 423 3.66E-71 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 A4R43_00275 387cbe5220e857c04694154ea84f0c96 436 Pfam PF03972 MmgE/PrpD family 8 394 2.4E-60 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 A4R43_00275 387cbe5220e857c04694154ea84f0c96 436 Gene3D G3DSA:1.10.4100.10 29 392 6.2E-58 T 14-10-2018 A4R43_27385 1dba99f875fd39a5e4e5f52687888899 198 SUPERFAMILY SSF51735 1 186 1.09E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_27385 1dba99f875fd39a5e4e5f52687888899 198 Gene3D G3DSA:3.40.50.720 1 197 2.4E-41 T 14-10-2018 A4R43_27385 1dba99f875fd39a5e4e5f52687888899 198 Pfam PF13460 NAD(P)H-binding 1 174 5.0E-36 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_32795 52fa7f6bbc84e253578d37231910c5e9 229 Gene3D G3DSA:3.40.50.2300 1 121 2.0E-36 T 14-10-2018 A4R43_32795 52fa7f6bbc84e253578d37231910c5e9 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 2.9E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_32795 52fa7f6bbc84e253578d37231910c5e9 229 Pfam PF00072 Response regulator receiver domain 4 113 1.1E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_32795 52fa7f6bbc84e253578d37231910c5e9 229 SUPERFAMILY SSF46894 132 228 7.65E-32 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_32795 52fa7f6bbc84e253578d37231910c5e9 229 SMART SM00862 151 227 1.9E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_32795 52fa7f6bbc84e253578d37231910c5e9 229 SUPERFAMILY SSF52172 3 119 1.11E-40 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_32795 52fa7f6bbc84e253578d37231910c5e9 229 SMART SM00448 2 112 1.3E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_32795 52fa7f6bbc84e253578d37231910c5e9 229 Gene3D G3DSA:1.10.10.10 123 229 3.0E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37355 278ff0ec2fbb54ca809f52dd8ddd2e66 167 Gene3D G3DSA:3.30.530.20 1 166 2.3E-29 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_37355 278ff0ec2fbb54ca809f52dd8ddd2e66 167 SUPERFAMILY SSF55961 7 165 2.75E-27 T 14-10-2018 A4R43_37355 278ff0ec2fbb54ca809f52dd8ddd2e66 167 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 160 4.4E-19 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_33745 dd9adab0454151a7e9c849ef1896db0c 430 SUPERFAMILY SSF46785 13 72 8.54E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_33745 dd9adab0454151a7e9c849ef1896db0c 430 Gene3D G3DSA:1.10.10.10 19 77 2.8E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_33745 dd9adab0454151a7e9c849ef1896db0c 430 SUPERFAMILY SSF53067 207 393 3.89E-40 T 14-10-2018 A4R43_33745 dd9adab0454151a7e9c849ef1896db0c 430 Pfam PF00480 ROK family 143 387 5.5E-41 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_33745 dd9adab0454151a7e9c849ef1896db0c 430 Gene3D G3DSA:3.30.420.40 92 382 8.0E-67 T 14-10-2018 A4R43_33745 dd9adab0454151a7e9c849ef1896db0c 430 Pfam PF09339 IclR helix-turn-helix domain 18 59 2.5E-5 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_33745 dd9adab0454151a7e9c849ef1896db0c 430 Gene3D G3DSA:3.30.420.40 206 372 8.0E-67 T 14-10-2018 A4R43_33745 dd9adab0454151a7e9c849ef1896db0c 430 SUPERFAMILY SSF53067 81 207 2.16E-15 T 14-10-2018 A4R43_26075 8db39640dc0d8f748606ac66515bdadc 502 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_26075 8db39640dc0d8f748606ac66515bdadc 502 Gene3D G3DSA:1.10.510.10 95 278 2.6E-38 T 14-10-2018 A4R43_26075 8db39640dc0d8f748606ac66515bdadc 502 SMART SM00220 13 274 6.2E-45 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_26075 8db39640dc0d8f748606ac66515bdadc 502 Gene3D G3DSA:3.30.200.20 4 91 4.6E-27 T 14-10-2018 A4R43_26075 8db39640dc0d8f748606ac66515bdadc 502 SUPERFAMILY SSF56112 9 357 3.55E-62 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_26075 8db39640dc0d8f748606ac66515bdadc 502 Pfam PF00069 Protein kinase domain 13 218 4.1E-38 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_05420 37d25c8f19e9a1f3efbcb6a84ce5ea80 322 Pfam PF04679 ATP dependent DNA ligase C terminal region 220 309 3.4E-21 T 14-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A4R43_05420 37d25c8f19e9a1f3efbcb6a84ce5ea80 322 Pfam PF01068 ATP dependent DNA ligase domain 32 197 1.4E-12 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A4R43_05420 37d25c8f19e9a1f3efbcb6a84ce5ea80 322 Gene3D G3DSA:2.40.50.140 204 320 4.3E-33 T 14-10-2018 A4R43_05420 37d25c8f19e9a1f3efbcb6a84ce5ea80 322 SUPERFAMILY SSF56091 9 197 1.44E-26 T 14-10-2018 A4R43_05420 37d25c8f19e9a1f3efbcb6a84ce5ea80 322 Gene3D G3DSA:3.30.1490.70 30 197 5.4E-38 T 14-10-2018 A4R43_05420 37d25c8f19e9a1f3efbcb6a84ce5ea80 322 SUPERFAMILY SSF50249 205 318 1.63E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_05420 37d25c8f19e9a1f3efbcb6a84ce5ea80 322 Gene3D G3DSA:3.30.470.30 43 156 5.4E-38 T 14-10-2018 A4R43_37710 09a723fa27b9f3f1138ea08a855ce4a4 255 Pfam PF03704 Bacterial transcriptional activator domain 99 244 1.1E-44 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37710 09a723fa27b9f3f1138ea08a855ce4a4 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 20 92 1.5E-12 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37710 09a723fa27b9f3f1138ea08a855ce4a4 255 SUPERFAMILY SSF48452 95 251 2.51E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37710 09a723fa27b9f3f1138ea08a855ce4a4 255 SUPERFAMILY SSF46894 3 92 1.67E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37710 09a723fa27b9f3f1138ea08a855ce4a4 255 SMART SM01043 99 244 8.4E-44 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37710 09a723fa27b9f3f1138ea08a855ce4a4 255 Gene3D G3DSA:1.10.10.10 1 94 1.9E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37710 09a723fa27b9f3f1138ea08a855ce4a4 255 SMART SM00862 16 92 5.2E-13 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37710 09a723fa27b9f3f1138ea08a855ce4a4 255 Gene3D G3DSA:1.25.40.10 96 255 1.2E-45 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_25375 c9bda7b124e722ac91bc342c3a1531e6 459 Pfam PF00324 Amino acid permease 13 422 1.3E-100 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A4R43_25375 c9bda7b124e722ac91bc342c3a1531e6 459 Gene3D G3DSA:1.20.1740.10 3 456 1.7E-66 T 14-10-2018 A4R43_25375 c9bda7b124e722ac91bc342c3a1531e6 459 PIRSF PIRSF006060 1 452 2.2E-64 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_25375 c9bda7b124e722ac91bc342c3a1531e6 459 ProSitePatterns PS00218 Amino acid permeases signature. 37 67 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A4R43_14740 cbd9f1b2ab45acac8649273f765b3dd5 304 Pfam PF01121 Dephospho-CoA kinase 4 177 3.4E-59 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A4R43_14740 cbd9f1b2ab45acac8649273f765b3dd5 304 Gene3D G3DSA:3.40.50.300 1 195 6.0E-67 T 14-10-2018 A4R43_14740 cbd9f1b2ab45acac8649273f765b3dd5 304 Pfam PF04229 GrpB protein 215 281 1.0E-10 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase A4R43_14740 cbd9f1b2ab45acac8649273f765b3dd5 304 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 176 2.2E-45 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A4R43_14740 cbd9f1b2ab45acac8649273f765b3dd5 304 Gene3D G3DSA:3.30.460.10 211 296 1.7E-8 T 14-10-2018 A4R43_14740 cbd9f1b2ab45acac8649273f765b3dd5 304 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 192 25.715 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A4R43_14740 cbd9f1b2ab45acac8649273f765b3dd5 304 SUPERFAMILY SSF52540 1 194 9.04E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14740 cbd9f1b2ab45acac8649273f765b3dd5 304 SUPERFAMILY SSF81301 215 299 3.04E-10 T 14-10-2018 A4R43_40125 93be3d26aedf7bf80d5d98669c91d6cd 297 Gene3D G3DSA:3.90.1200.10 116 288 4.1E-18 T 14-10-2018 A4R43_40125 93be3d26aedf7bf80d5d98669c91d6cd 297 Pfam PF01636 Phosphotransferase enzyme family 36 259 1.9E-33 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_40125 93be3d26aedf7bf80d5d98669c91d6cd 297 SUPERFAMILY SSF56112 16 267 2.29E-46 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_40125 93be3d26aedf7bf80d5d98669c91d6cd 297 Gene3D G3DSA:3.30.200.20 12 102 9.1E-11 T 14-10-2018 A4R43_20335 5cec23ba247c03c8aef3fef5a7cd16a8 312 SUPERFAMILY SSF53474 5 294 8.11E-52 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20335 5cec23ba247c03c8aef3fef5a7cd16a8 312 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 112 126 6.0E-11 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_20335 5cec23ba247c03c8aef3fef5a7cd16a8 312 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 38 46 6.0E-11 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_20335 5cec23ba247c03c8aef3fef5a7cd16a8 312 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 64 75 6.0E-11 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_20335 5cec23ba247c03c8aef3fef5a7cd16a8 312 Pfam PF00561 alpha/beta hydrolase fold 39 294 3.8E-21 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_20335 5cec23ba247c03c8aef3fef5a7cd16a8 312 PIRSF PIRSF006431 1 312 4.0E-111 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 A4R43_20335 5cec23ba247c03c8aef3fef5a7cd16a8 312 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 10 306 1.5E-91 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 A4R43_20335 5cec23ba247c03c8aef3fef5a7cd16a8 312 Gene3D G3DSA:3.40.50.1820 1 312 1.8E-83 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_33510 ef2c2f68573bb4fa8e2b65686f45bcf2 149 Gene3D G3DSA:3.10.129.10 2 148 1.9E-49 T 14-10-2018 A4R43_33510 ef2c2f68573bb4fa8e2b65686f45bcf2 149 Hamap MF_00799 UPF0336 protein . 1 148 30.585 T 14-10-2018 IPR016709 Uncharacterised protein family UPF0336 A4R43_33510 ef2c2f68573bb4fa8e2b65686f45bcf2 149 PIRSF PIRSF018072 2 149 6.0E-53 T 14-10-2018 IPR016709 Uncharacterised protein family UPF0336 A4R43_33510 ef2c2f68573bb4fa8e2b65686f45bcf2 149 SUPERFAMILY SSF54637 8 148 3.52E-38 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_33510 ef2c2f68573bb4fa8e2b65686f45bcf2 149 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 4.9E-33 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 A4R43_12000 1830428dd547a9e9985e634158dd4095 461 SUPERFAMILY SSF53850 35 436 5.98E-38 T 14-10-2018 A4R43_12000 1830428dd547a9e9985e634158dd4095 461 Pfam PF01547 Bacterial extracellular solute-binding protein 41 345 2.0E-17 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_12000 1830428dd547a9e9985e634158dd4095 461 Gene3D G3DSA:3.40.190.10 32 459 1.7E-41 T 14-10-2018 A4R43_18630 04cdf8df04bd622cb5eede105f68313e 525 Gene3D G3DSA:3.20.20.360 1 406 2.0E-182 T 14-10-2018 A4R43_18630 04cdf8df04bd622cb5eede105f68313e 525 SUPERFAMILY SSF51645 9 524 1.07E-176 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_18630 04cdf8df04bd622cb5eede105f68313e 525 PIRSF PIRSF001363 1 525 1.6E-228 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_18630 04cdf8df04bd622cb5eede105f68313e 525 Pfam PF01274 Malate synthase 6 524 1.8E-189 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_18630 04cdf8df04bd622cb5eede105f68313e 525 ProSitePatterns PS00510 Malate synthase signature. 261 276 - T 14-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_18630 04cdf8df04bd622cb5eede105f68313e 525 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 17 524 1.3E-228 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A4R43_18630 04cdf8df04bd622cb5eede105f68313e 525 Gene3D G3DSA:1.20.1220.12 410 524 2.6E-40 T 14-10-2018 A4R43_31590 05cf4ffc8bd6e7592cef3e603330dfb0 378 Gene3D G3DSA:3.20.20.140 52 339 1.1E-122 T 14-10-2018 A4R43_31590 05cf4ffc8bd6e7592cef3e603330dfb0 378 Gene3D G3DSA:2.30.40.10 8 371 1.1E-122 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_31590 05cf4ffc8bd6e7592cef3e603330dfb0 378 PIRSF PIRSF038994 2 377 7.3E-112 T 14-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A4R43_31590 05cf4ffc8bd6e7592cef3e603330dfb0 378 SUPERFAMILY SSF51556 51 345 3.86E-92 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_31590 05cf4ffc8bd6e7592cef3e603330dfb0 378 SUPERFAMILY SSF51338 1 365 6.61E-12 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_31590 05cf4ffc8bd6e7592cef3e603330dfb0 378 Pfam PF01979 Amidohydrolase family 47 360 1.8E-23 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_31590 05cf4ffc8bd6e7592cef3e603330dfb0 378 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 19 362 2.9E-76 T 14-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A4R43_25855 62f0a6b4dbd8f0f568de5ac1dd2fa018 320 Pfam PF00268 Ribonucleotide reductase, small chain 30 279 1.6E-17 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_25855 62f0a6b4dbd8f0f568de5ac1dd2fa018 320 Gene3D G3DSA:1.10.620.20 2 294 3.0E-112 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4R43_25855 62f0a6b4dbd8f0f568de5ac1dd2fa018 320 SUPERFAMILY SSF47240 22 300 6.24E-55 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_08455 055c6a63011ddf37cbd194b4670f5e7a 132 SUPERFAMILY SSF54593 1 124 8.59E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_08455 055c6a63011ddf37cbd194b4670f5e7a 132 Gene3D G3DSA:3.10.180.10 6 121 1.0E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_08455 055c6a63011ddf37cbd194b4670f5e7a 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 117 2.4E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_34400 989a1130ce8b2e97cc476294ab369766 307 SUPERFAMILY SSF103481 44 142 2.62E-11 T 14-10-2018 A4R43_34400 989a1130ce8b2e97cc476294ab369766 307 Pfam PF00892 EamA-like transporter family 12 139 4.3E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_34400 989a1130ce8b2e97cc476294ab369766 307 Pfam PF00892 EamA-like transporter family 150 285 4.3E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_34400 989a1130ce8b2e97cc476294ab369766 307 SUPERFAMILY SSF103481 189 288 3.01E-13 T 14-10-2018 A4R43_29330 2e67e7e4c240c97da4088d31d9f9ea50 158 ProSitePatterns PS00194 Thioredoxin family active site. 66 84 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A4R43_29330 2e67e7e4c240c97da4088d31d9f9ea50 158 PRINTS PR00421 Thioredoxin family signature 113 124 5.3E-7 T 14-10-2018 A4R43_29330 2e67e7e4c240c97da4088d31d9f9ea50 158 PRINTS PR00421 Thioredoxin family signature 73 82 5.3E-7 T 14-10-2018 A4R43_29330 2e67e7e4c240c97da4088d31d9f9ea50 158 PRINTS PR00421 Thioredoxin family signature 65 73 5.3E-7 T 14-10-2018 A4R43_29330 2e67e7e4c240c97da4088d31d9f9ea50 158 SUPERFAMILY SSF52833 46 148 6.89E-33 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_29330 2e67e7e4c240c97da4088d31d9f9ea50 158 TIGRFAM TIGR01068 thioredoxin: thioredoxin 50 147 4.6E-32 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4R43_29330 2e67e7e4c240c97da4088d31d9f9ea50 158 Pfam PF00085 Thioredoxin 49 147 6.0E-28 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 A4R43_29330 2e67e7e4c240c97da4088d31d9f9ea50 158 Gene3D G3DSA:3.40.30.10 45 149 4.5E-30 T 14-10-2018 A4R43_17125 71e6d48b0287e8b7bfdb6d3b53c09ecf 295 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 115 120 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4R43_17125 71e6d48b0287e8b7bfdb6d3b53c09ecf 295 Gene3D G3DSA:2.40.10.10 81 188 2.6E-37 T 14-10-2018 A4R43_17125 71e6d48b0287e8b7bfdb6d3b53c09ecf 295 SUPERFAMILY SSF50494 87 281 3.68E-19 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_17125 71e6d48b0287e8b7bfdb6d3b53c09ecf 295 Gene3D G3DSA:2.40.10.10 189 295 9.1E-34 T 14-10-2018 A4R43_02525 55052ae6432f1b590889e61ea53fbcc2 295 SUPERFAMILY SSF161098 26 295 1.96E-61 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_02525 55052ae6432f1b590889e61ea53fbcc2 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 282 4.5E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_02525 55052ae6432f1b590889e61ea53fbcc2 295 Gene3D G3DSA:1.10.3720.10 21 285 1.1E-54 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_31755 cd789af683f2658ad21eae4752910475 344 Pfam PF01212 Beta-eliminating lyase 10 291 1.0E-74 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A4R43_31755 cd789af683f2658ad21eae4752910475 344 Gene3D G3DSA:3.90.1150.10 258 344 3.6E-20 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_31755 cd789af683f2658ad21eae4752910475 344 Gene3D G3DSA:3.40.640.10 5 257 5.2E-78 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_31755 cd789af683f2658ad21eae4752910475 344 PIRSF PIRSF017617 2 344 8.6E-106 T 14-10-2018 IPR023603 Threonine aldolase A4R43_31755 cd789af683f2658ad21eae4752910475 344 SUPERFAMILY SSF53383 9 341 1.5E-98 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_08990 bbfeecc1ffc5dc48001393acca00cb8e 607 SUPERFAMILY SSF53850 33 530 1.23E-115 T 14-10-2018 A4R43_08990 bbfeecc1ffc5dc48001393acca00cb8e 607 Gene3D G3DSA:3.10.105.10 297 518 8.6E-50 T 14-10-2018 A4R43_08990 bbfeecc1ffc5dc48001393acca00cb8e 607 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 452 1.9E-83 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_08990 bbfeecc1ffc5dc48001393acca00cb8e 607 PIRSF PIRSF002741 8 547 5.0E-93 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_08990 bbfeecc1ffc5dc48001393acca00cb8e 607 Gene3D G3DSA:3.40.190.10 18 287 3.4E-68 T 14-10-2018 A4R43_18780 d8090a8af881d9f7e4d07994d9bb659a 139 SUPERFAMILY SSF53933 49 137 7.65E-33 T 14-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 A4R43_18780 d8090a8af881d9f7e4d07994d9bb659a 139 Pfam PF00545 ribonuclease 57 135 9.0E-26 T 14-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 A4R43_18780 d8090a8af881d9f7e4d07994d9bb659a 139 Gene3D G3DSA:3.10.450.30 45 139 3.0E-35 T 14-10-2018 A4R43_11145 954af664e6593eff3a53a3a67fb49a67 441 SUPERFAMILY SSF109854 8 144 6.41E-20 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_11145 954af664e6593eff3a53a3a67fb49a67 441 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 15 432 1.7E-133 T 14-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 A4R43_11145 954af664e6593eff3a53a3a67fb49a67 441 Pfam PF03781 Sulfatase-modifying factor enzyme 1 175 433 3.1E-65 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A4R43_11145 954af664e6593eff3a53a3a67fb49a67 441 Pfam PF12867 DinB superfamily 16 148 2.3E-25 T 14-10-2018 IPR024775 DinB-like domain A4R43_11145 954af664e6593eff3a53a3a67fb49a67 441 SUPERFAMILY SSF56436 176 435 7.16E-77 T 14-10-2018 IPR016187 C-type lectin fold A4R43_11145 954af664e6593eff3a53a3a67fb49a67 441 Gene3D G3DSA:1.20.120.450 5 151 3.8E-8 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_11145 954af664e6593eff3a53a3a67fb49a67 441 Gene3D G3DSA:3.90.1580.10 163 440 5.9E-61 T 14-10-2018 A4R43_11145 954af664e6593eff3a53a3a67fb49a67 441 Hamap MF_02035 Hercynine oxygenase [egtB]. 3 435 51.763 T 14-10-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 A4R43_31855 714d9ee1b13ab9b2335dda6edaf1120c 555 SUPERFAMILY SSF90123 2 301 3.27E-52 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_31855 714d9ee1b13ab9b2335dda6edaf1120c 555 SUPERFAMILY SSF52540 315 551 9.67E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31855 714d9ee1b13ab9b2335dda6edaf1120c 555 Pfam PF00664 ABC transporter transmembrane region 9 278 1.1E-25 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_31855 714d9ee1b13ab9b2335dda6edaf1120c 555 SMART SM00382 345 529 9.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_31855 714d9ee1b13ab9b2335dda6edaf1120c 555 Gene3D G3DSA:1.20.1560.10 1 304 2.3E-52 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_31855 714d9ee1b13ab9b2335dda6edaf1120c 555 Gene3D G3DSA:3.40.50.300 314 555 1.6E-68 T 14-10-2018 A4R43_31855 714d9ee1b13ab9b2335dda6edaf1120c 555 Pfam PF00005 ABC transporter 336 483 5.1E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_05425 765e40b320e052c2b846d0ee58abf3f5 217 SUPERFAMILY SSF109755 2 216 9.0E-35 T 14-10-2018 A4R43_05425 765e40b320e052c2b846d0ee58abf3f5 217 Pfam PF01895 PhoU domain 18 103 6.4E-11 T 14-10-2018 IPR026022 PhoU domain A4R43_05425 765e40b320e052c2b846d0ee58abf3f5 217 Gene3D G3DSA:1.20.58.220 1 215 4.0E-40 T 14-10-2018 IPR038078 PhoU-like domain superfamily A4R43_14170 89656fabd9921b99a3639efe5b1861ae 287 Pfam PF02616 Segregation and condensation protein ScpA 42 262 6.3E-61 T 14-10-2018 IPR003768 Segregation and condensation protein A A4R43_20935 62e71840b4f18ac8e4a4f114691de3fa 409 SUPERFAMILY SSF51905 2 359 5.92E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_20935 62e71840b4f18ac8e4a4f114691de3fa 409 Gene3D G3DSA:3.50.50.60 4 325 3.0E-133 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_20935 62e71840b4f18ac8e4a4f114691de3fa 409 Gene3D G3DSA:3.30.9.40 66 274 3.0E-133 T 14-10-2018 A4R43_12915 834d6cb0ebf69b87f9688642a7e21eaf 347 Gene3D G3DSA:1.10.3470.10 18 345 1.8E-89 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_12915 834d6cb0ebf69b87f9688642a7e21eaf 347 Pfam PF01032 FecCD transport family 32 341 7.5E-85 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_12915 834d6cb0ebf69b87f9688642a7e21eaf 347 SUPERFAMILY SSF81345 14 341 6.93E-76 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_05500 70c0a6e91def860032030bb8060444ec 409 Pfam PF13556 PucR C-terminal helix-turn-helix domain 339 392 1.4E-10 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_05500 70c0a6e91def860032030bb8060444ec 409 Gene3D G3DSA:1.10.10.2840 270 396 7.8E-18 T 14-10-2018 A4R43_04065 01ad9730df10d25f572a04f4031772cf 518 Gene3D G3DSA:3.10.105.10 262 491 6.2E-80 T 14-10-2018 A4R43_04065 01ad9730df10d25f572a04f4031772cf 518 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 429 2.2E-57 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_04065 01ad9730df10d25f572a04f4031772cf 518 PIRSF PIRSF002741 1 515 2.5E-58 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_04065 01ad9730df10d25f572a04f4031772cf 518 Gene3D G3DSA:3.90.76.10 47 186 6.2E-80 T 14-10-2018 A4R43_04065 01ad9730df10d25f572a04f4031772cf 518 Gene3D G3DSA:3.40.190.10 187 501 6.2E-80 T 14-10-2018 A4R43_04065 01ad9730df10d25f572a04f4031772cf 518 SUPERFAMILY SSF53850 32 516 6.7E-92 T 14-10-2018 A4R43_04710 f45a62485bc1e53ba53f346addbe6983 205 Pfam PF00156 Phosphoribosyl transferase domain 16 161 2.6E-21 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4R43_04710 f45a62485bc1e53ba53f346addbe6983 205 SUPERFAMILY SSF53271 16 185 1.7E-41 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_04710 f45a62485bc1e53ba53f346addbe6983 205 Gene3D G3DSA:3.40.50.2020 9 193 2.2E-61 T 14-10-2018 A4R43_04710 f45a62485bc1e53ba53f346addbe6983 205 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 14 191 35.361 T 14-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4R43_20125 fca53f2e393c4f9991a159611349e75d 452 SUPERFAMILY SSF103473 13 447 2.22E-49 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_20125 fca53f2e393c4f9991a159611349e75d 452 Pfam PF07690 Major Facilitator Superfamily 24 377 1.9E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_36310 129a896458d5dce3c21cec7f95823956 97 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 20 91 7.1E-22 T 14-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 A4R43_36310 129a896458d5dce3c21cec7f95823956 97 SUPERFAMILY SSF54736 20 94 1.2E-23 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4R43_36310 129a896458d5dce3c21cec7f95823956 97 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 2 97 17.506 T 14-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS A4R43_36310 129a896458d5dce3c21cec7f95823956 97 Gene3D G3DSA:3.30.1390.10 4 96 2.8E-18 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4R43_10925 7a4bab8d8a84101f406c069dab0e9381 519 Gene3D G3DSA:3.40.50.12780 11 421 5.9E-107 T 14-10-2018 A4R43_10925 7a4bab8d8a84101f406c069dab0e9381 519 Gene3D G3DSA:3.30.300.310 422 519 3.2E-28 T 14-10-2018 A4R43_10925 7a4bab8d8a84101f406c069dab0e9381 519 Pfam PF00501 AMP-binding enzyme 27 423 1.2E-89 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_10925 7a4bab8d8a84101f406c069dab0e9381 519 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 508 1.3E-14 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_10925 7a4bab8d8a84101f406c069dab0e9381 519 SUPERFAMILY SSF56801 15 518 7.46E-137 T 14-10-2018 A4R43_10925 7a4bab8d8a84101f406c069dab0e9381 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_30175 8928c0fb2cf12bdf85a244e76b71f5f4 488 Pfam PF00501 AMP-binding enzyme 10 386 2.1E-105 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_30175 8928c0fb2cf12bdf85a244e76b71f5f4 488 SUPERFAMILY SSF56801 8 482 1.1E-157 T 14-10-2018 A4R43_30175 8928c0fb2cf12bdf85a244e76b71f5f4 488 Gene3D G3DSA:3.40.50.12780 2 379 9.8E-121 T 14-10-2018 A4R43_30175 8928c0fb2cf12bdf85a244e76b71f5f4 488 ProSitePatterns PS00455 Putative AMP-binding domain signature. 141 152 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_30175 8928c0fb2cf12bdf85a244e76b71f5f4 488 Gene3D G3DSA:3.30.300.310 382 485 8.2E-34 T 14-10-2018 A4R43_30175 8928c0fb2cf12bdf85a244e76b71f5f4 488 Pfam PF13193 AMP-binding enzyme C-terminal domain 395 470 4.7E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_19135 333748e5c44e1bafe0ff7198945b1633 457 SUPERFAMILY SSF143548 17 158 1.12E-47 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A4R43_19135 333748e5c44e1bafe0ff7198945b1633 457 Pfam PF03313 Serine dehydratase alpha chain 189 451 2.2E-100 T 14-10-2018 IPR005130 Serine dehydratase-like, alpha subunit A4R43_19135 333748e5c44e1bafe0ff7198945b1633 457 Pfam PF03315 Serine dehydratase beta chain 4 156 4.5E-60 T 14-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A4R43_19135 333748e5c44e1bafe0ff7198945b1633 457 Gene3D G3DSA:3.30.1330.90 11 160 3.4E-54 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A4R43_19135 333748e5c44e1bafe0ff7198945b1633 457 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 454 1.0E-206 T 14-10-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A4R43_04010 c663bc0f42a4ac209e5e11912863ac04 247 Pfam PF08241 Methyltransferase domain 37 112 2.9E-7 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_04010 c663bc0f42a4ac209e5e11912863ac04 247 Gene3D G3DSA:3.40.50.150 2 246 6.3E-43 T 14-10-2018 A4R43_04010 c663bc0f42a4ac209e5e11912863ac04 247 SUPERFAMILY SSF53335 2 139 1.28E-14 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 Gene3D G3DSA:3.40.120.10 208 320 5.3E-21 T 14-10-2018 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 320 429 2.6E-16 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 SUPERFAMILY SSF53738 42 212 5.89E-43 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 SUPERFAMILY SSF53738 299 436 4.32E-26 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 291 306 3.6E-8 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 146 160 3.6E-8 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 224 243 3.6E-8 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 Gene3D G3DSA:3.30.310.50 440 527 3.4E-7 T 14-10-2018 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 221 306 1.2E-22 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 442 524 1.4E-9 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 147 156 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 SUPERFAMILY SSF55957 426 525 1.57E-12 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 Gene3D G3DSA:3.40.120.10 41 192 8.9E-47 T 14-10-2018 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 Gene3D G3DSA:3.40.120.10 321 435 2.7E-26 T 14-10-2018 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 SUPERFAMILY SSF53738 208 307 3.53E-20 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_34945 e53d2a879c6af517a36ffbebd0f4f942 544 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 52 186 1.4E-39 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4R43_18365 7bbfd3d7d6ca5d9c7ef9c4149ad2b801 266 SUPERFAMILY SSF53335 32 194 3.84E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_18365 7bbfd3d7d6ca5d9c7ef9c4149ad2b801 266 Gene3D G3DSA:3.40.50.150 12 243 8.4E-31 T 14-10-2018 A4R43_18365 7bbfd3d7d6ca5d9c7ef9c4149ad2b801 266 Pfam PF08241 Methyltransferase domain 51 145 5.9E-18 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_32100 f8d8db43a8e9546e62b62f0d72bc1f21 306 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 5 301 1.2E-83 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A4R43_32100 f8d8db43a8e9546e62b62f0d72bc1f21 306 Gene3D G3DSA:1.10.3720.10 61 301 1.1E-28 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_32100 f8d8db43a8e9546e62b62f0d72bc1f21 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 297 2.5E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_32100 f8d8db43a8e9546e62b62f0d72bc1f21 306 SUPERFAMILY SSF161098 28 296 2.62E-29 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_38715 d0370fad103b72367439e850184deef3 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_38715 d0370fad103b72367439e850184deef3 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_38715 d0370fad103b72367439e850184deef3 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_38715 d0370fad103b72367439e850184deef3 297 SUPERFAMILY SSF46785 1 105 2.39E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38715 d0370fad103b72367439e850184deef3 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.8E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_38715 d0370fad103b72367439e850184deef3 297 Gene3D G3DSA:3.40.190.10 166 268 4.4E-36 T 14-10-2018 A4R43_38715 d0370fad103b72367439e850184deef3 297 Pfam PF03466 LysR substrate binding domain 84 292 5.7E-35 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_38715 d0370fad103b72367439e850184deef3 297 SUPERFAMILY SSF53850 85 295 6.21E-31 T 14-10-2018 A4R43_38715 d0370fad103b72367439e850184deef3 297 Gene3D G3DSA:3.40.190.10 91 278 4.4E-36 T 14-10-2018 A4R43_38715 d0370fad103b72367439e850184deef3 297 Gene3D G3DSA:1.10.10.10 1 90 5.7E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 SUPERFAMILY SSF52540 3 298 4.69E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 Gene3D G3DSA:3.40.50.300 4 275 1.4E-138 T 14-10-2018 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 360 3.0E-128 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 360 43.65 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 Pfam PF01926 50S ribosome-binding GTPase 5 129 1.7E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 9.5E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 9.5E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 9.5E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 9.5E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 Gene3D G3DSA:3.10.20.30 48 358 1.4E-138 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 PIRSF PIRSF006641 1 360 6.7E-139 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 Pfam PF06071 Protein of unknown function (DUF933) 276 359 4.8E-39 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 SUPERFAMILY SSF81271 276 360 3.49E-35 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4R43_23450 1a57868fd986c232cb362af45a900dc7 360 Gene3D G3DSA:1.10.150.300 113 198 1.4E-138 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 A4R43_01880 3d092600ccf918f9bbc37d47e091f91d 474 Gene3D G3DSA:1.20.1720.10 19 234 3.1E-43 T 14-10-2018 A4R43_01880 3d092600ccf918f9bbc37d47e091f91d 474 Gene3D G3DSA:1.20.1250.20 271 471 3.0E-17 T 14-10-2018 A4R43_01880 3d092600ccf918f9bbc37d47e091f91d 474 Pfam PF07690 Major Facilitator Superfamily 24 417 2.1E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_01880 3d092600ccf918f9bbc37d47e091f91d 474 SUPERFAMILY SSF103473 18 464 1.22E-56 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_21865 1b0ff459a2a9921fbc5cee5c6c8063d8 435 SUPERFAMILY SSF51556 48 351 1.02E-66 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_21865 1b0ff459a2a9921fbc5cee5c6c8063d8 435 Pfam PF01979 Amidohydrolase family 47 408 1.8E-40 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_21865 1b0ff459a2a9921fbc5cee5c6c8063d8 435 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 1 426 2.1E-142 T 14-10-2018 IPR010252 Formiminoglutamate deiminase A4R43_21865 1b0ff459a2a9921fbc5cee5c6c8063d8 435 Gene3D G3DSA:2.30.40.10 9 412 1.6E-142 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_21865 1b0ff459a2a9921fbc5cee5c6c8063d8 435 Gene3D G3DSA:3.20.20.140 50 421 1.6E-142 T 14-10-2018 A4R43_21865 1b0ff459a2a9921fbc5cee5c6c8063d8 435 SUPERFAMILY SSF51338 340 415 7.46E-9 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_40870 c918150a23b27f831e6a17a2ca24995d 320 Gene3D G3DSA:3.60.15.10 13 241 5.7E-35 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_40870 c918150a23b27f831e6a17a2ca24995d 320 SUPERFAMILY SSF56281 17 311 1.34E-48 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_40870 c918150a23b27f831e6a17a2ca24995d 320 Pfam PF00753 Metallo-beta-lactamase superfamily 34 222 2.8E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_40870 c918150a23b27f831e6a17a2ca24995d 320 SMART SM00849 34 223 4.4E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_29605 88f85878faccb7f99fd3540a1b7ceb95 259 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 72 246 6.1E-10 T 14-10-2018 IPR000477 Reverse transcriptase domain A4R43_29605 88f85878faccb7f99fd3540a1b7ceb95 259 SUPERFAMILY SSF56672 16 252 1.93E-9 T 14-10-2018 A4R43_34190 a8aeaba5f12c75093c4ef363da13c840 332 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_34190 a8aeaba5f12c75093c4ef363da13c840 332 Gene3D G3DSA:3.90.180.10 14 311 3.2E-95 T 14-10-2018 A4R43_34190 a8aeaba5f12c75093c4ef363da13c840 332 Pfam PF00107 Zinc-binding dehydrogenase 172 280 4.3E-14 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_34190 a8aeaba5f12c75093c4ef363da13c840 332 SUPERFAMILY SSF51735 136 293 3.71E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_34190 a8aeaba5f12c75093c4ef363da13c840 332 SUPERFAMILY SSF50129 1 170 5.93E-54 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_34190 a8aeaba5f12c75093c4ef363da13c840 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 130 3.4E-33 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_34190 a8aeaba5f12c75093c4ef363da13c840 332 Gene3D G3DSA:3.40.50.720 149 277 3.2E-95 T 14-10-2018 A4R43_39195 126fd11183d55b195c96c227b1498bc3 760 Gene3D G3DSA:1.10.439.10 25 196 1.0E-57 T 14-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 A4R43_39195 126fd11183d55b195c96c227b1498bc3 760 Gene3D G3DSA:1.10.1400.10 514 688 3.1E-202 T 14-10-2018 A4R43_39195 126fd11183d55b195c96c227b1498bc3 760 Gene3D G3DSA:3.60.20.10 217 748 3.1E-202 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_39195 126fd11183d55b195c96c227b1498bc3 760 Gene3D G3DSA:2.30.120.10 293 369 3.1E-202 T 14-10-2018 A4R43_39195 126fd11183d55b195c96c227b1498bc3 760 SUPERFAMILY SSF56235 31 755 1.05E-148 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_39195 126fd11183d55b195c96c227b1498bc3 760 Pfam PF01804 Penicillin amidase 35 747 2.9E-128 T 14-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 A4R43_32480 c280050dc8ac6abb2ae3e17df262e226 192 SUPERFAMILY SSF54637 25 159 1.59E-31 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_32480 c280050dc8ac6abb2ae3e17df262e226 192 Gene3D G3DSA:3.10.129.10 26 163 8.9E-32 T 14-10-2018 A4R43_32480 c280050dc8ac6abb2ae3e17df262e226 192 Pfam PF03061 Thioesterase superfamily 74 143 5.3E-8 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_08805 4108327d165fe6abeeada6a0dfc15ce1 374 PRINTS PR00412 Epoxide hydrolase signature 347 369 5.8E-12 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08805 4108327d165fe6abeeada6a0dfc15ce1 374 PRINTS PR00412 Epoxide hydrolase signature 102 120 5.8E-12 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08805 4108327d165fe6abeeada6a0dfc15ce1 374 PRINTS PR00412 Epoxide hydrolase signature 176 189 5.8E-12 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08805 4108327d165fe6abeeada6a0dfc15ce1 374 PRINTS PR00412 Epoxide hydrolase signature 131 146 5.8E-12 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08805 4108327d165fe6abeeada6a0dfc15ce1 374 Gene3D G3DSA:3.40.50.1820 7 374 1.2E-135 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08805 4108327d165fe6abeeada6a0dfc15ce1 374 Pfam PF06441 Epoxide hydrolase N terminus 6 111 2.4E-35 T 14-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 A4R43_08805 4108327d165fe6abeeada6a0dfc15ce1 374 SUPERFAMILY SSF53474 3 372 1.29E-95 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08805 4108327d165fe6abeeada6a0dfc15ce1 374 PIRSF PIRSF001112 1 374 1.1E-113 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_02110 c65e2b03e8b220f84807cb220109bc28 314 Pfam PF00682 HMGL-like 14 285 2.5E-35 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4R43_02110 c65e2b03e8b220f84807cb220109bc28 314 Gene3D G3DSA:3.20.20.70 10 290 7.0E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_02110 c65e2b03e8b220f84807cb220109bc28 314 SUPERFAMILY SSF51569 11 286 2.49E-60 T 14-10-2018 A4R43_40160 a2a7b956dc226fc652794a5e83a7d71a 196 Pfam PF03358 NADPH-dependent FMN reductase 1 150 3.3E-32 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4R43_40160 a2a7b956dc226fc652794a5e83a7d71a 196 SUPERFAMILY SSF52218 1 171 8.57E-25 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_40160 a2a7b956dc226fc652794a5e83a7d71a 196 Gene3D G3DSA:3.40.50.360 1 172 7.7E-47 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_40160 a2a7b956dc226fc652794a5e83a7d71a 196 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 1 194 9.8E-81 T 14-10-2018 IPR023932 Uncharacterised protein family, CE1759 A4R43_36420 1e828a3d9ed92d2b659f96a18ebe1783 171 Pfam PF12867 DinB superfamily 11 161 4.1E-17 T 14-10-2018 IPR024775 DinB-like domain A4R43_36420 1e828a3d9ed92d2b659f96a18ebe1783 171 SUPERFAMILY SSF109854 5 155 2.52E-5 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_03950 a2a4f10635cd9b692d792beafd5787f5 366 Gene3D G3DSA:1.10.600.10 45 362 3.4E-67 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_03950 a2a4f10635cd9b692d792beafd5787f5 366 SUPERFAMILY SSF48576 48 362 9.5E-36 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_04075 931b05e03e047eb9ad4be5d8610b5c12 323 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 1 318 1.4E-107 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 A4R43_04075 931b05e03e047eb9ad4be5d8610b5c12 323 Gene3D G3DSA:3.40.718.10 1 320 6.0E-131 T 14-10-2018 A4R43_04075 931b05e03e047eb9ad4be5d8610b5c12 323 SUPERFAMILY SSF53659 1 319 3.56E-104 T 14-10-2018 A4R43_04075 931b05e03e047eb9ad4be5d8610b5c12 323 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 24 314 2.5E-103 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 SUPERFAMILY SSF51735 7 248 1.76E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 Pfam PF00106 short chain dehydrogenase 7 201 1.5E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 193 2.2E-4 T 14-10-2018 A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 9.9E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.9E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 9.9E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 9.9E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 9.9E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 9.9E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 Gene3D G3DSA:3.40.50.720 1 252 9.9E-68 T 14-10-2018 A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 8.8E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 8.8E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.8E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28840 1ce4484850d9367f825e5b066aacecaf 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_33785 d74f6753365771167fd56fa6b2a68e49 479 SUPERFAMILY SSF51658 3 277 2.23E-46 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_33785 d74f6753365771167fd56fa6b2a68e49 479 Pfam PF01261 Xylose isomerase-like TIM barrel 22 231 4.0E-28 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_33785 d74f6753365771167fd56fa6b2a68e49 479 Gene3D G3DSA:3.20.20.150 2 276 1.2E-51 T 14-10-2018 A4R43_16995 eab840c21dbd959521ce9625d2bc015a 218 Gene3D G3DSA:3.10.180.10 3 126 3.0E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16995 eab840c21dbd959521ce9625d2bc015a 218 SUPERFAMILY SSF54593 4 120 5.81E-9 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_41655 b5c28a6f7e4bc60ee91e8ac6416e9d72 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.3E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_41655 b5c28a6f7e4bc60ee91e8ac6416e9d72 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.3E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_41655 b5c28a6f7e4bc60ee91e8ac6416e9d72 192 SUPERFAMILY SSF46689 3 85 8.21E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_41655 b5c28a6f7e4bc60ee91e8ac6416e9d72 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_41655 b5c28a6f7e4bc60ee91e8ac6416e9d72 192 Gene3D G3DSA:1.10.357.10 1 192 3.9E-23 T 14-10-2018 A4R43_16665 b4c02920b2918fc9de3ea255ec76e05a 336 SUPERFAMILY SSF51197 5 286 5.01E-86 T 14-10-2018 A4R43_16665 b4c02920b2918fc9de3ea255ec76e05a 336 PRINTS PR00682 Isopenicillin N synthase signature 28 45 1.3E-10 T 14-10-2018 A4R43_16665 b4c02920b2918fc9de3ea255ec76e05a 336 PRINTS PR00682 Isopenicillin N synthase signature 199 220 1.3E-10 T 14-10-2018 A4R43_16665 b4c02920b2918fc9de3ea255ec76e05a 336 PRINTS PR00682 Isopenicillin N synthase signature 235 261 1.3E-10 T 14-10-2018 A4R43_16665 b4c02920b2918fc9de3ea255ec76e05a 336 Gene3D G3DSA:2.60.120.330 2 304 7.2E-88 T 14-10-2018 IPR027443 Isopenicillin N synthase-like A4R43_16665 b4c02920b2918fc9de3ea255ec76e05a 336 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 181 275 4.6E-21 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 A4R43_16665 b4c02920b2918fc9de3ea255ec76e05a 336 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 7 129 5.2E-37 T 14-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain A4R43_21260 eedd441699c5c008ef1550644e701bd8 391 Gene3D G3DSA:3.40.440.10 6 259 8.7E-65 T 14-10-2018 A4R43_21260 eedd441699c5c008ef1550644e701bd8 391 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 391 42.807 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_21260 eedd441699c5c008ef1550644e701bd8 391 SUPERFAMILY SSF52540 4 343 2.34E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21260 eedd441699c5c008ef1550644e701bd8 391 SMART SM00788 4 385 1.8E-20 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_21260 eedd441699c5c008ef1550644e701bd8 391 Pfam PF00709 Adenylosuccinate synthetase 5 342 6.1E-75 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_21260 eedd441699c5c008ef1550644e701bd8 391 Gene3D G3DSA:3.90.170.10 275 344 4.5E-9 T 14-10-2018 A4R43_21260 eedd441699c5c008ef1550644e701bd8 391 Gene3D G3DSA:1.10.300.10 104 212 8.7E-65 T 14-10-2018 A4R43_21260 eedd441699c5c008ef1550644e701bd8 391 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4R43_19855 e92b8465145d8ec16c0c1d82056cd19b 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 9.3E-19 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19855 e92b8465145d8ec16c0c1d82056cd19b 202 SUPERFAMILY SSF46689 6 79 1.15E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19855 e92b8465145d8ec16c0c1d82056cd19b 202 Gene3D G3DSA:1.10.357.10 4 199 1.7E-39 T 14-10-2018 A4R43_19855 e92b8465145d8ec16c0c1d82056cd19b 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19855 e92b8465145d8ec16c0c1d82056cd19b 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00405 3fd65058216eb1e2623747db9f8f16fc 330 SUPERFAMILY SSF53659 7 324 5.92E-81 T 14-10-2018 A4R43_00405 3fd65058216eb1e2623747db9f8f16fc 330 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 84 318 2.9E-72 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 A4R43_00405 3fd65058216eb1e2623747db9f8f16fc 330 Gene3D G3DSA:3.40.718.10 1 325 4.4E-93 T 14-10-2018 A4R43_41055 15b5f3e068da51f27d64a4a1a579c0ad 77 Gene3D G3DSA:3.30.1230.10 1 70 1.5E-13 T 14-10-2018 IPR035931 YlxR-like superfamily A4R43_41055 15b5f3e068da51f27d64a4a1a579c0ad 77 Pfam PF04296 Protein of unknown function (DUF448) 2 64 2.2E-21 T 14-10-2018 IPR007393 Domain of unknown function DUF448 A4R43_41055 15b5f3e068da51f27d64a4a1a579c0ad 77 SUPERFAMILY SSF64376 1 68 6.41E-20 T 14-10-2018 IPR035931 YlxR-like superfamily A4R43_19380 43755e1d613b3300ab22263ac015312b 391 PIRSF PIRSF000429 1 391 1.4E-128 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.1E-134 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 SUPERFAMILY SSF53901 3 267 1.09E-78 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 Pfam PF00108 Thiolase, N-terminal domain 4 258 2.7E-70 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 Gene3D G3DSA:3.40.47.10 141 389 4.3E-146 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 Pfam PF02803 Thiolase, C-terminal domain 269 390 3.6E-41 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 SUPERFAMILY SSF53901 269 390 2.5E-40 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A4R43_19380 43755e1d613b3300ab22263ac015312b 391 Gene3D G3DSA:3.40.47.10 6 274 4.3E-146 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_36080 e05d5d6ef37275ec3c5d0993175c9b71 273 Gene3D G3DSA:1.10.510.10 82 237 9.4E-64 T 14-10-2018 A4R43_36080 e05d5d6ef37275ec3c5d0993175c9b71 273 Gene3D G3DSA:1.20.1270.240 104 261 9.4E-64 T 14-10-2018 A4R43_36080 e05d5d6ef37275ec3c5d0993175c9b71 273 PIRSF PIRSF006221 18 272 1.4E-53 T 14-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 A4R43_36080 e05d5d6ef37275ec3c5d0993175c9b71 273 Gene3D G3DSA:3.30.200.20 1 72 5.0E-12 T 14-10-2018 A4R43_36080 e05d5d6ef37275ec3c5d0993175c9b71 273 Pfam PF03881 Fructosamine kinase 40 266 2.0E-43 T 14-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 A4R43_36080 e05d5d6ef37275ec3c5d0993175c9b71 273 SUPERFAMILY SSF56112 17 262 2.04E-42 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_33500 1a46417a0858e18b462e841a7cd04790 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.5E-20 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33500 1a46417a0858e18b462e841a7cd04790 54 Pfam PF00471 Ribosomal protein L33 9 54 2.2E-22 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33500 1a46417a0858e18b462e841a7cd04790 54 Gene3D G3DSA:2.20.28.120 2 54 2.8E-24 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33500 1a46417a0858e18b462e841a7cd04790 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33500 1a46417a0858e18b462e841a7cd04790 54 SUPERFAMILY SSF57829 4 54 1.04E-19 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4R43_33500 1a46417a0858e18b462e841a7cd04790 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.517 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11695 62331eceadc7d73e16011eeabd4387ed 353 SUPERFAMILY SSF54991 247 351 4.58E-9 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 A4R43_11695 62331eceadc7d73e16011eeabd4387ed 353 Pfam PF01409 tRNA synthetases class II core domain (F) 44 235 9.0E-25 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A4R43_11695 62331eceadc7d73e16011eeabd4387ed 353 SUPERFAMILY SSF55681 20 233 4.04E-25 T 14-10-2018 A4R43_11695 62331eceadc7d73e16011eeabd4387ed 353 Gene3D G3DSA:3.30.930.10 9 247 1.9E-40 T 14-10-2018 A4R43_11695 62331eceadc7d73e16011eeabd4387ed 353 Pfam PF03147 Ferredoxin-fold anticodon binding domain 252 350 1.3E-7 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A4R43_11695 62331eceadc7d73e16011eeabd4387ed 353 Gene3D G3DSA:3.30.70.380 254 353 3.0E-7 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 A4R43_11695 62331eceadc7d73e16011eeabd4387ed 353 SMART SM00896 252 353 2.0E-6 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A4R43_11310 e709706d2f3ceca8955f3be24367cfc8 52 Pfam PF01783 Ribosomal L32p protein family 2 37 6.8E-13 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11310 e709706d2f3ceca8955f3be24367cfc8 52 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 34 1.7E-11 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_11310 e709706d2f3ceca8955f3be24367cfc8 52 SUPERFAMILY SSF57829 1 37 1.16E-9 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4R43_11310 e709706d2f3ceca8955f3be24367cfc8 52 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 51 13.004 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_13765 05714d28eeae6305bd58e618f4aecab7 367 SUPERFAMILY SSF51556 200 365 8.32E-10 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_13765 05714d28eeae6305bd58e618f4aecab7 367 Pfam PF04909 Amidohydrolase 141 365 1.9E-7 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_13765 05714d28eeae6305bd58e618f4aecab7 367 Gene3D G3DSA:3.20.20.140 3 366 6.8E-93 T 14-10-2018 A4R43_03990 a1f3444c7dd7123f43a9324d649e30ba 255 SMART SM00342 155 237 7.0E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03990 a1f3444c7dd7123f43a9324d649e30ba 255 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 192 233 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_03990 a1f3444c7dd7123f43a9324d649e30ba 255 Gene3D G3DSA:1.10.10.60 135 239 1.3E-19 T 14-10-2018 A4R43_03990 a1f3444c7dd7123f43a9324d649e30ba 255 Pfam PF12833 Helix-turn-helix domain 161 237 1.6E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_03990 a1f3444c7dd7123f43a9324d649e30ba 255 SUPERFAMILY SSF46689 138 188 4.43E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38095 bcd26284353b374d9d48ce5260d385ca 455 SUPERFAMILY SSF53850 24 451 9.83E-46 T 14-10-2018 A4R43_38095 bcd26284353b374d9d48ce5260d385ca 455 Pfam PF01547 Bacterial extracellular solute-binding protein 58 337 3.5E-27 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_38095 bcd26284353b374d9d48ce5260d385ca 455 Gene3D G3DSA:3.40.190.10 33 454 2.8E-55 T 14-10-2018 A4R43_32580 f070564ed483c6e396490bf7bacbe225 457 Pfam PF01425 Amidase 26 437 2.2E-104 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_32580 f070564ed483c6e396490bf7bacbe225 457 Gene3D G3DSA:3.90.1300.10 7 457 2.9E-127 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_32580 f070564ed483c6e396490bf7bacbe225 457 ProSitePatterns PS00571 Amidases signature. 152 183 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4R43_32580 f070564ed483c6e396490bf7bacbe225 457 SUPERFAMILY SSF75304 7 445 8.76E-118 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_17660 bf8bfa292f30cb607c41d9f71299cee4 226 Gene3D G3DSA:3.40.50.300 3 223 6.4E-64 T 14-10-2018 A4R43_17660 bf8bfa292f30cb607c41d9f71299cee4 226 Pfam PF00005 ABC transporter 22 169 1.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_17660 bf8bfa292f30cb607c41d9f71299cee4 226 SMART SM00382 30 218 1.8E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_17660 bf8bfa292f30cb607c41d9f71299cee4 226 SUPERFAMILY SSF52540 5 221 6.66E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 Gene3D G3DSA:3.40.50.720 6 347 2.3E-123 T 14-10-2018 A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 SUPERFAMILY SSF55347 129 337 3.0E-64 T 14-10-2018 A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 PIRSF PIRSF000148 2 353 2.6E-106 T 14-10-2018 A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 336 8.8E-45 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 SUPERFAMILY SSF51735 5 156 5.07E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 117 3.9E-27 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 350 9.9E-115 T 14-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 SMART SM00859 4 120 1.6E-33 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 Gene3D G3DSA:3.30.360.10 128 333 2.3E-123 T 14-10-2018 A4R43_27330 a7f12c501905d584698fe392e7a2fc28 354 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 350 31.965 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4R43_10585 16e22862d73fe267a8b1855fd33b2351 114 Gene3D G3DSA:3.40.630.30 3 113 1.4E-15 T 14-10-2018 A4R43_10585 16e22862d73fe267a8b1855fd33b2351 114 SUPERFAMILY SSF55729 2 106 1.72E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_10585 16e22862d73fe267a8b1855fd33b2351 114 Pfam PF00583 Acetyltransferase (GNAT) family 47 100 6.7E-10 T 14-10-2018 IPR000182 GNAT domain A4R43_07705 cb218a847775e38799fcede0ff54c5b6 211 Gene3D G3DSA:3.40.50.850 1 211 2.2E-50 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_07705 cb218a847775e38799fcede0ff54c5b6 211 Pfam PF00857 Isochorismatase family 7 181 1.0E-27 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4R43_07705 cb218a847775e38799fcede0ff54c5b6 211 SUPERFAMILY SSF52499 4 187 4.84E-43 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 84 91 9.8E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 145 164 9.8E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 235 243 9.8E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 182 193 9.8E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 Gene3D G3DSA:2.40.30.10 31 132 6.6E-22 T 14-10-2018 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 Pfam PF00175 Oxidoreductase NAD-binding domain 146 250 1.5E-13 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 Gene3D G3DSA:3.40.50.80 138 267 8.0E-27 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 PRINTS PR00410 Phenol hydroxylase reductase family signature 145 164 7.7E-13 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 PRINTS PR00410 Phenol hydroxylase reductase family signature 235 243 7.7E-13 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 PRINTS PR00410 Phenol hydroxylase reductase family signature 129 138 7.7E-13 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 PRINTS PR00410 Phenol hydroxylase reductase family signature 65 77 7.7E-13 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 SUPERFAMILY SSF63380 37 136 3.57E-22 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 SUPERFAMILY SSF54292 259 359 1.85E-17 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 Pfam PF00970 Oxidoreductase FAD-binding domain 50 134 6.6E-12 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 Gene3D G3DSA:3.10.20.30 268 361 2.6E-11 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_18135 e48964e5e71c179cdafcb32ef8de3ede 361 SUPERFAMILY SSF52343 134 269 5.76E-29 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_23020 3b2ae2953f824a1d58e9e6375b2221d7 199 Pfam PF14124 Domain of unknown function (DUF4291) 8 186 1.4E-71 T 14-10-2018 IPR025633 Protein of unknown function DUF4291 A4R43_25395 08a72fe43effa852266fce22aa8514bb 248 SUPERFAMILY SSF52096 2 246 5.57E-71 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_25395 08a72fe43effa852266fce22aa8514bb 248 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_25395 08a72fe43effa852266fce22aa8514bb 248 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 244 9.0E-55 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_25395 08a72fe43effa852266fce22aa8514bb 248 Gene3D G3DSA:3.90.226.10 3 247 2.4E-72 T 14-10-2018 A4R43_11840 11b7df1fc9a79c504713f5218924d324 270 Gene3D G3DSA:2.160.20.80 155 251 1.4E-18 T 14-10-2018 A4R43_11840 11b7df1fc9a79c504713f5218924d324 270 Pfam PF00805 Pentapeptide repeats (8 copies) 185 221 3.1E-11 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_11840 11b7df1fc9a79c504713f5218924d324 270 SUPERFAMILY SSF141571 57 260 3.14E-20 T 14-10-2018 A4R43_41045 6a9a7429256c1801dc5d6e08338adb62 172 Gene3D G3DSA:3.30.300.70 3 82 1.2E-16 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily A4R43_41045 6a9a7429256c1801dc5d6e08338adb62 172 Pfam PF02576 RimP N-terminal domain 12 85 2.9E-19 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A4R43_41045 6a9a7429256c1801dc5d6e08338adb62 172 Pfam PF17384 RimP C-terminal SH3 domain 88 149 1.0E-5 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A4R43_41045 6a9a7429256c1801dc5d6e08338adb62 172 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 149 20.115 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 A4R43_41045 6a9a7429256c1801dc5d6e08338adb62 172 SUPERFAMILY SSF75420 6 85 1.16E-18 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily A4R43_11510 592aee4a2c172cabd5272e72c25c09e2 117 SMART SM00418 25 103 4.1E-28 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_11510 592aee4a2c172cabd5272e72c25c09e2 117 Gene3D G3DSA:1.10.10.10 2 115 2.2E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11510 592aee4a2c172cabd5272e72c25c09e2 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 2.2E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_11510 592aee4a2c172cabd5272e72c25c09e2 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 2.2E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_11510 592aee4a2c172cabd5272e72c25c09e2 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 2.2E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_11510 592aee4a2c172cabd5272e72c25c09e2 117 Pfam PF01022 Bacterial regulatory protein, arsR family 33 77 1.3E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_11510 592aee4a2c172cabd5272e72c25c09e2 117 SUPERFAMILY SSF46785 17 101 5.88E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38785 ab253f3fddbc45a6bbbea0eb045cb8ec 392 Gene3D G3DSA:1.20.1250.20 4 189 2.7E-13 T 14-10-2018 A4R43_38785 ab253f3fddbc45a6bbbea0eb045cb8ec 392 SUPERFAMILY SSF103473 7 385 4.32E-40 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_38785 ab253f3fddbc45a6bbbea0eb045cb8ec 392 Gene3D G3DSA:1.20.1250.20 193 379 7.7E-22 T 14-10-2018 A4R43_38785 ab253f3fddbc45a6bbbea0eb045cb8ec 392 Pfam PF07690 Major Facilitator Superfamily 8 214 1.9E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_38785 ab253f3fddbc45a6bbbea0eb045cb8ec 392 Pfam PF07690 Major Facilitator Superfamily 226 388 1.0E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_36260 243d6a0660f6102e51feb7f428526d53 250 SUPERFAMILY SSF102462 154 249 3.14E-16 T 14-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A4R43_36260 243d6a0660f6102e51feb7f428526d53 250 Gene3D G3DSA:3.40.1490.10 153 248 6.2E-10 T 14-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A4R43_36260 243d6a0660f6102e51feb7f428526d53 250 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 155 247 5.2E-7 T 14-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 PRINTS PR00944 Copper ion binding protein signature 3 15 5.0E-7 T 14-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 PRINTS PR00944 Copper ion binding protein signature 28 41 5.0E-7 T 14-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 PRINTS PR00944 Copper ion binding protein signature 15 28 5.0E-7 T 14-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 PRINTS PR00944 Copper ion binding protein signature 53 66 5.0E-7 T 14-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 SUPERFAMILY SSF55008 1 66 2.23E-18 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 Pfam PF00403 Heavy-metal-associated domain 5 65 1.7E-15 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 4 66 4.1E-19 T 14-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A4R43_02890 08bc7d322c54a349a284654ce0f62094 68 Gene3D G3DSA:3.30.70.100 2 66 4.3E-20 T 14-10-2018 A4R43_24500 0c5698a1b07961b0e3238d4667b59499 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 239 263 8.2E-9 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24500 0c5698a1b07961b0e3238d4667b59499 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 328 347 8.2E-9 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24500 0c5698a1b07961b0e3238d4667b59499 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 380 406 8.2E-9 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_24500 0c5698a1b07961b0e3238d4667b59499 500 Pfam PF00361 Proton-conducting membrane transporter 126 421 2.0E-52 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_11860 3b701033d2c6a597219c31fc4ea90490 274 Gene3D G3DSA:3.90.1200.10 95 258 2.5E-13 T 14-10-2018 A4R43_11860 3b701033d2c6a597219c31fc4ea90490 274 Pfam PF01636 Phosphotransferase enzyme family 56 227 8.1E-18 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_11860 3b701033d2c6a597219c31fc4ea90490 274 SUPERFAMILY SSF56112 8 252 4.59E-25 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_24570 8bf47209d726562ed10e7d3211c1f7a2 706 Gene3D G3DSA:3.40.50.300 36 194 7.8E-23 T 14-10-2018 A4R43_24570 8bf47209d726562ed10e7d3211c1f7a2 706 SUPERFAMILY SSF48452 496 679 6.32E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_24570 8bf47209d726562ed10e7d3211c1f7a2 706 Gene3D G3DSA:1.25.40.10 493 695 1.6E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_24570 8bf47209d726562ed10e7d3211c1f7a2 706 SUPERFAMILY SSF52540 36 299 1.38E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24570 8bf47209d726562ed10e7d3211c1f7a2 706 Pfam PF00931 NB-ARC domain 58 307 6.2E-7 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_06900 ade1b25ca5a0c20fe391c5c5cc8668fb 243 PIRSF PIRSF029958 1 243 1.3E-115 T 14-10-2018 IPR008701 Necrosis inducing protein A4R43_06900 ade1b25ca5a0c20fe391c5c5cc8668fb 243 Pfam PF05630 Necrosis inducing protein (NPP1) 34 232 1.9E-62 T 14-10-2018 IPR008701 Necrosis inducing protein A4R43_26675 793c770c920f48ecd0c47f1cc3e57cc1 352 Gene3D G3DSA:3.40.50.1980 40 233 9.3E-37 T 14-10-2018 A4R43_26675 793c770c920f48ecd0c47f1cc3e57cc1 352 Pfam PF01297 Zinc-uptake complex component A periplasmic 41 348 9.3E-46 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A4R43_26675 793c770c920f48ecd0c47f1cc3e57cc1 352 SUPERFAMILY SSF53807 37 350 1.03E-57 T 14-10-2018 A4R43_28320 44a26cc1711beb9ded10a2cd24e3fa45 210 Pfam PF14273 Domain of unknown function (DUF4360) 30 209 8.8E-70 T 14-10-2018 IPR025649 Protein of unknown function DUF4360 A4R43_23810 a0cb5005f92032f7c1d0dc719f9599ff 143 Pfam PF01638 HxlR-like helix-turn-helix 39 125 3.8E-26 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_23810 a0cb5005f92032f7c1d0dc719f9599ff 143 SUPERFAMILY SSF46785 27 135 1.69E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_23810 a0cb5005f92032f7c1d0dc719f9599ff 143 Gene3D G3DSA:1.10.10.10 16 138 4.3E-42 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18960 107239f1d2389f3916cb7302608c04cb 282 SUPERFAMILY SSF51658 40 280 2.49E-40 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_18960 107239f1d2389f3916cb7302608c04cb 282 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 25 0.0012 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4R43_18960 107239f1d2389f3916cb7302608c04cb 282 Pfam PF01261 Xylose isomerase-like TIM barrel 66 236 1.5E-15 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_18960 107239f1d2389f3916cb7302608c04cb 282 Gene3D G3DSA:3.20.20.150 24 282 3.0E-69 T 14-10-2018 A4R43_00485 5480e89344b243ddb9a4945f01aad231 330 SUPERFAMILY SSF52151 30 243 8.89E-29 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_00485 5480e89344b243ddb9a4945f01aad231 330 Gene3D G3DSA:3.40.1090.10 15 127 2.7E-12 T 14-10-2018 A4R43_00485 5480e89344b243ddb9a4945f01aad231 330 Pfam PF01734 Patatin-like phospholipase 35 205 5.1E-15 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A4R43_41200 2ee817c043dc5f139257ef3fd0483b78 188 Gene3D G3DSA:3.40.50.360 6 184 1.8E-45 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_41200 2ee817c043dc5f139257ef3fd0483b78 188 SUPERFAMILY SSF52218 7 177 4.5E-41 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_41200 2ee817c043dc5f139257ef3fd0483b78 188 Pfam PF03358 NADPH-dependent FMN reductase 7 149 2.0E-34 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4R43_17940 1bc3f6104e1e17421dfa170f5a7dd872 479 ProSitePatterns PS00218 Amino acid permeases signature. 56 86 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A4R43_17940 1bc3f6104e1e17421dfa170f5a7dd872 479 Pfam PF00324 Amino acid permease 31 469 1.4E-102 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A4R43_17940 1bc3f6104e1e17421dfa170f5a7dd872 479 Gene3D G3DSA:1.20.1740.10 23 475 4.5E-54 T 14-10-2018 A4R43_17940 1bc3f6104e1e17421dfa170f5a7dd872 479 PIRSF PIRSF006060 7 476 1.2E-59 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_31390 d34548e88ea38443219c86c767b0185e 459 Pfam PF08386 TAP-like protein 358 450 5.5E-23 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_31390 d34548e88ea38443219c86c767b0185e 459 SUPERFAMILY SSF53474 78 428 8.86E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_31390 d34548e88ea38443219c86c767b0185e 459 Pfam PF00561 alpha/beta hydrolase fold 78 255 1.4E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_38990 cc843fc6a3b579929d2ddb7601002c7b 129 SUPERFAMILY SSF54593 11 127 1.15E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_38990 cc843fc6a3b579929d2ddb7601002c7b 129 Gene3D G3DSA:3.10.180.10 2 127 3.9E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_38990 cc843fc6a3b579929d2ddb7601002c7b 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 122 6.3E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_15600 94d5c5be5c97b0be3b2e8d5f975ec5cb 331 SUPERFAMILY SSF53474 39 252 2.03E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_15600 94d5c5be5c97b0be3b2e8d5f975ec5cb 331 Pfam PF12740 Chlorophyllase enzyme 89 203 6.0E-7 T 14-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 A4R43_15600 94d5c5be5c97b0be3b2e8d5f975ec5cb 331 Gene3D G3DSA:3.40.50.1820 1 318 1.3E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_28395 fb7ff44bab31640313533ebd14305248 316 Gene3D G3DSA:3.40.50.720 37 316 6.4E-64 T 14-10-2018 A4R43_28395 fb7ff44bab31640313533ebd14305248 316 Pfam PF00106 short chain dehydrogenase 43 236 7.1E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28395 fb7ff44bab31640313533ebd14305248 316 SUPERFAMILY SSF51735 40 285 2.05E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_28395 fb7ff44bab31640313533ebd14305248 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 44 61 1.8E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28395 fb7ff44bab31640313533ebd14305248 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 127 1.8E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28395 fb7ff44bab31640313533ebd14305248 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 238 1.8E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_28395 fb7ff44bab31640313533ebd14305248 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 177 1.8E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_10885 88b545f50f028af899bb8f5d6df7a334 295 Gene3D G3DSA:3.40.50.10900 24 228 1.4E-95 T 14-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A4R43_10885 88b545f50f028af899bb8f5d6df7a334 295 SUPERFAMILY SSF159659 17 264 2.35E-90 T 14-10-2018 A4R43_10885 88b545f50f028af899bb8f5d6df7a334 295 Pfam PF09754 PAC2 family 30 248 1.4E-52 T 14-10-2018 IPR019151 Proteasome assembly chaperone 2 A4R43_10885 88b545f50f028af899bb8f5d6df7a334 295 PIRSF PIRSF028754 8 294 1.4E-111 T 14-10-2018 IPR008492 Protein of unknown function DUF774 A4R43_10885 88b545f50f028af899bb8f5d6df7a334 295 Gene3D G3DSA:1.10.287.100 229 264 1.4E-95 T 14-10-2018 A4R43_28190 709729f62dab55984a6812dbfe911ce5 244 SMART SM00563 38 152 4.0E-38 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_28190 709729f62dab55984a6812dbfe911ce5 244 Pfam PF01553 Acyltransferase 24 149 1.2E-29 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_28190 709729f62dab55984a6812dbfe911ce5 244 SUPERFAMILY SSF69593 13 209 3.01E-36 T 14-10-2018 A4R43_06595 f3964450ffa56a141ee532609e4d11de 457 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 19 453 1.1E-139 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4R43_06595 f3964450ffa56a141ee532609e4d11de 457 Pfam PF02447 GntP family permease 18 453 1.1E-147 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4R43_06595 f3964450ffa56a141ee532609e4d11de 457 PIRSF PIRSF002746 11 457 6.3E-148 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4R43_21070 ff8106a518e9368f3fb75ed1d4943963 726 SUPERFAMILY SSF48619 106 186 8.42E-8 T 14-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A4R43_21070 ff8106a518e9368f3fb75ed1d4943963 726 Gene3D G3DSA:1.20.90.10 91 190 3.5E-9 T 14-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A4R43_21070 ff8106a518e9368f3fb75ed1d4943963 726 Pfam PF09056 Prokaryotic phospholipase A2 107 186 3.8E-7 T 14-10-2018 IPR015141 Phospholipase A2, prokaryotic/fungal A4R43_26460 40fac37f545fa0bf3d565a0a38d874cf 230 Pfam PF07510 Protein of unknown function (DUF1524) 116 221 7.4E-9 T 14-10-2018 IPR011089 Domain of unknown function DUF1524 A4R43_07585 9bdffa0bdfc6f568986bea91e4d4bcd2 99 Pfam PF11239 Protein of unknown function (DUF3040) 1 75 9.0E-12 T 14-10-2018 IPR021401 Protein of unknown function DUF3040 A4R43_10185 de856fe2efeb8f0a24857eadd7a2fa4e 249 SUPERFAMILY SSF52540 12 230 1.3E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10185 de856fe2efeb8f0a24857eadd7a2fa4e 249 Gene3D G3DSA:3.40.50.300 10 246 2.4E-68 T 14-10-2018 A4R43_10185 de856fe2efeb8f0a24857eadd7a2fa4e 249 SMART SM00382 40 226 7.7E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_10185 de856fe2efeb8f0a24857eadd7a2fa4e 249 Pfam PF00005 ABC transporter 31 177 2.1E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_10185 de856fe2efeb8f0a24857eadd7a2fa4e 249 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_02015 724af03d47eebceef20f35e9294699a6 259 SUPERFAMILY SSF51197 3 252 2.11E-52 T 14-10-2018 A4R43_02015 724af03d47eebceef20f35e9294699a6 259 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 15 212 1.8E-37 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase A4R43_02015 724af03d47eebceef20f35e9294699a6 259 Gene3D G3DSA:2.60.120.620 1 254 2.0E-69 T 14-10-2018 A4R43_28920 4ad391492147c777b685f8ab12958de7 436 SUPERFAMILY SSF47413 15 63 5.32E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_28920 4ad391492147c777b685f8ab12958de7 436 SMART SM00530 12 67 1.4E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_28920 4ad391492147c777b685f8ab12958de7 436 Gene3D G3DSA:1.10.260.40 1 64 9.9E-8 T 14-10-2018 A4R43_28920 4ad391492147c777b685f8ab12958de7 436 Pfam PF01381 Helix-turn-helix 15 63 7.5E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_28920 4ad391492147c777b685f8ab12958de7 436 SUPERFAMILY SSF48452 191 300 4.17E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28920 4ad391492147c777b685f8ab12958de7 436 Gene3D G3DSA:1.25.40.10 181 310 4.6E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_28600 f7944e7171023f3cb81f14b738946345 115 Pfam PF06108 Protein of unknown function (DUF952) 5 95 4.5E-24 T 14-10-2018 IPR009297 Protein of unknown function DUF952 A4R43_28600 f7944e7171023f3cb81f14b738946345 115 SUPERFAMILY SSF56399 2 110 3.16E-25 T 14-10-2018 A4R43_28600 f7944e7171023f3cb81f14b738946345 115 Gene3D G3DSA:3.20.170.20 1 114 9.1E-33 T 14-10-2018 A4R43_13955 fb20b7eabfd61ff241a6583fc115505f 490 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 30 456 5.9E-51 T 14-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 A4R43_13955 fb20b7eabfd61ff241a6583fc115505f 490 PIRSF PIRSF002744 1 487 7.2E-92 T 14-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 A4R43_13955 fb20b7eabfd61ff241a6583fc115505f 490 Gene3D G3DSA:1.10.4160.10 21 458 1.9E-32 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily A4R43_05155 b1de65695ccda11d15a63a0cafd936d4 392 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 158 304 1.1E-40 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_05155 b1de65695ccda11d15a63a0cafd936d4 392 Gene3D G3DSA:1.10.260.150 118 388 1.4E-71 T 14-10-2018 A4R43_05155 b1de65695ccda11d15a63a0cafd936d4 392 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 158 304 5.1E-44 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_06835 63b829b041e02107af9b5c14e709da9a 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 61 2.5E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06835 63b829b041e02107af9b5c14e709da9a 217 SMART SM00345 11 68 8.5E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_06835 63b829b041e02107af9b5c14e709da9a 217 Pfam PF07729 FCD domain 78 200 2.0E-26 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06835 63b829b041e02107af9b5c14e709da9a 217 SMART SM00895 78 201 3.0E-19 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_06835 63b829b041e02107af9b5c14e709da9a 217 SUPERFAMILY SSF46785 3 72 1.15E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06835 63b829b041e02107af9b5c14e709da9a 217 Gene3D G3DSA:1.20.120.530 72 214 2.4E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_06835 63b829b041e02107af9b5c14e709da9a 217 SUPERFAMILY SSF48008 74 209 3.92E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_06835 63b829b041e02107af9b5c14e709da9a 217 Gene3D G3DSA:1.10.10.10 2 69 5.3E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12575 6e68801548fa9c6f99c4b2dcfff71725 451 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 153 1.9E-9 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_12575 6e68801548fa9c6f99c4b2dcfff71725 451 SUPERFAMILY SSF53756 3 432 3.37E-77 T 14-10-2018 A4R43_12575 6e68801548fa9c6f99c4b2dcfff71725 451 Gene3D G3DSA:3.40.50.2000 3 416 2.3E-90 T 14-10-2018 A4R43_12575 6e68801548fa9c6f99c4b2dcfff71725 451 Gene3D G3DSA:3.40.50.2000 246 415 2.3E-90 T 14-10-2018 A4R43_22440 b152640cabc9717fe53941047f90b445 673 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 406 610 4.8E-21 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_22440 b152640cabc9717fe53941047f90b445 673 SUPERFAMILY SSF68912 36 74 6.28E-5 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily A4R43_22440 b152640cabc9717fe53941047f90b445 673 Gene3D G3DSA:3.40.50.300 381 664 1.3E-118 T 14-10-2018 A4R43_22440 b152640cabc9717fe53941047f90b445 673 Pfam PF07497 Rho termination factor, RNA-binding domain 300 375 3.9E-29 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 A4R43_22440 b152640cabc9717fe53941047f90b445 673 SMART SM00382 417 602 5.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_22440 b152640cabc9717fe53941047f90b445 673 Hamap MF_01884 Transcription termination factor Rho [rho]. 293 666 198.211 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4R43_22440 b152640cabc9717fe53941047f90b445 673 SUPERFAMILY SSF50249 300 375 1.7E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_22440 b152640cabc9717fe53941047f90b445 673 Pfam PF07498 Rho termination factor, N-terminal domain 36 74 3.4E-10 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A4R43_22440 b152640cabc9717fe53941047f90b445 673 TIGRFAM TIGR00767 rho: transcription termination factor Rho 36 664 4.5E-200 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4R43_22440 b152640cabc9717fe53941047f90b445 673 SUPERFAMILY SSF52540 340 618 1.78E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22440 b152640cabc9717fe53941047f90b445 673 SMART SM00357 301 368 3.3E-7 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 A4R43_22440 b152640cabc9717fe53941047f90b445 673 SMART SM00959 35 77 8.4E-9 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A4R43_22440 b152640cabc9717fe53941047f90b445 673 Gene3D G3DSA:2.40.50.140 229 379 1.9E-31 T 14-10-2018 A4R43_01245 729aa7c0f90b764ef95121f5b2c4b6a4 204 Pfam PF01471 Putative peptidoglycan binding domain 144 201 1.8E-15 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_01245 729aa7c0f90b764ef95121f5b2c4b6a4 204 SUPERFAMILY SSF47090 130 202 3.14E-19 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_01245 729aa7c0f90b764ef95121f5b2c4b6a4 204 Gene3D G3DSA:1.10.101.10 132 203 9.1E-26 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_06570 deade2b9f85ae08b0a2ba02e0647ee04 191 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 19 129 1.0E-7 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_06570 deade2b9f85ae08b0a2ba02e0647ee04 191 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 19 185 2.4E-26 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_06570 deade2b9f85ae08b0a2ba02e0647ee04 191 Gene3D G3DSA:1.20.120.450 11 64 1.2E-5 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_06570 deade2b9f85ae08b0a2ba02e0647ee04 191 SUPERFAMILY SSF109854 10 135 1.98E-13 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_06570 deade2b9f85ae08b0a2ba02e0647ee04 191 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 16 185 1.2E-17 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_26800 f7ac9ef02194aee5d3e3f5fac2fc7716 159 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 83 94 - T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4R43_26800 f7ac9ef02194aee5d3e3f5fac2fc7716 159 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 128 1.4E-34 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4R43_26800 f7ac9ef02194aee5d3e3f5fac2fc7716 159 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 128 7.4E-30 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4R43_26800 f7ac9ef02194aee5d3e3f5fac2fc7716 159 SUPERFAMILY SSF55083 1 150 1.18E-43 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4R43_26800 f7ac9ef02194aee5d3e3f5fac2fc7716 159 Gene3D G3DSA:3.30.70.560 1 153 4.7E-43 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4R43_18065 35913ae2a6c517765a903e25f2af4627 404 Pfam PF13556 PucR C-terminal helix-turn-helix domain 336 393 1.5E-19 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_18065 35913ae2a6c517765a903e25f2af4627 404 Gene3D G3DSA:1.10.10.2840 273 399 1.2E-39 T 14-10-2018 A4R43_14295 8d73052966d3745c8a612428c256c69c 215 SUPERFAMILY SSF46689 5 79 3.95E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14295 8d73052966d3745c8a612428c256c69c 215 Gene3D G3DSA:1.10.357.10 3 201 2.5E-19 T 14-10-2018 A4R43_14295 8d73052966d3745c8a612428c256c69c 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 2.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31980 70899510a789f62397a7f67db6705c26 315 Gene3D G3DSA:3.30.360.10 142 299 7.9E-13 T 14-10-2018 A4R43_31980 70899510a789f62397a7f67db6705c26 315 SUPERFAMILY SSF51735 4 138 2.23E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_31980 70899510a789f62397a7f67db6705c26 315 Gene3D G3DSA:3.40.50.720 2 141 9.5E-33 T 14-10-2018 A4R43_31980 70899510a789f62397a7f67db6705c26 315 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 123 7.4E-19 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_31980 70899510a789f62397a7f67db6705c26 315 SUPERFAMILY SSF55347 152 250 1.59E-8 T 14-10-2018 A4R43_04665 4f16795ded7cfc04ff6b271baffd80b1 368 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 4 358 61.544 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4R43_04665 4f16795ded7cfc04ff6b271baffd80b1 368 Pfam PF01761 3-dehydroquinate synthase 66 322 3.9E-94 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4R43_04665 4f16795ded7cfc04ff6b271baffd80b1 368 Gene3D G3DSA:1.20.1090.10 172 359 1.7E-67 T 14-10-2018 A4R43_04665 4f16795ded7cfc04ff6b271baffd80b1 368 Gene3D G3DSA:3.40.50.1970 1 171 4.0E-59 T 14-10-2018 A4R43_04665 4f16795ded7cfc04ff6b271baffd80b1 368 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 338 3.3E-106 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4R43_04665 4f16795ded7cfc04ff6b271baffd80b1 368 PIRSF PIRSF001455 4 346 1.8E-98 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4R43_04665 4f16795ded7cfc04ff6b271baffd80b1 368 SUPERFAMILY SSF56796 13 353 6.41E-99 T 14-10-2018 A4R43_09335 6b9d5a18bfcc2075ebca204b4ecf5088 374 SUPERFAMILY SSF53383 4 372 8.9E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_09335 6b9d5a18bfcc2075ebca204b4ecf5088 374 Gene3D G3DSA:3.90.1150.10 4 370 8.0E-116 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_09335 6b9d5a18bfcc2075ebca204b4ecf5088 374 Pfam PF00202 Aminotransferase class-III 31 315 1.4E-44 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_09335 6b9d5a18bfcc2075ebca204b4ecf5088 374 Gene3D G3DSA:3.40.640.10 61 297 8.0E-116 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_39015 898f1d1b41bf14adbd90c4eeb8b45f6a 437 Pfam PF00012 Hsp70 protein 87 355 1.0E-11 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_39015 898f1d1b41bf14adbd90c4eeb8b45f6a 437 Gene3D G3DSA:3.30.420.40 5 353 5.6E-64 T 14-10-2018 A4R43_39015 898f1d1b41bf14adbd90c4eeb8b45f6a 437 Gene3D G3DSA:3.30.420.40 170 343 5.6E-64 T 14-10-2018 A4R43_39015 898f1d1b41bf14adbd90c4eeb8b45f6a 437 Gene3D G3DSA:3.90.640.10 210 287 5.6E-64 T 14-10-2018 A4R43_39015 898f1d1b41bf14adbd90c4eeb8b45f6a 437 SUPERFAMILY SSF53067 3 159 1.21E-20 T 14-10-2018 A4R43_39015 898f1d1b41bf14adbd90c4eeb8b45f6a 437 SUPERFAMILY SSF53067 172 355 6.63E-21 T 14-10-2018 A4R43_00230 831a6b681f949503473ed8d9fbe89998 461 Pfam PF03972 MmgE/PrpD family 5 444 1.4E-115 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 A4R43_00230 831a6b681f949503473ed8d9fbe89998 461 Gene3D G3DSA:1.10.4100.10 25 424 8.8E-104 T 14-10-2018 A4R43_00230 831a6b681f949503473ed8d9fbe89998 461 SUPERFAMILY SSF103378 1 454 1.07E-110 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 A4R43_00230 831a6b681f949503473ed8d9fbe89998 461 Gene3D G3DSA:3.30.1330.120 270 408 8.8E-104 T 14-10-2018 A4R43_10645 eb83c17f2d300ac7f428b9698fa163e1 212 Pfam PF01810 LysE type translocator 16 208 2.5E-27 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_10645 eb83c17f2d300ac7f428b9698fa163e1 212 PIRSF PIRSF006324 1 210 7.9E-53 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_00355 c9df41988646cc31668e59be7fc1f6f1 446 Gene3D G3DSA:2.60.120.200 51 209 3.2E-12 T 14-10-2018 A4R43_13785 28d4f9426216b379bf256d8db1fcba55 300 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 15 212 5.4E-33 T 14-10-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain A4R43_30575 0d82dde7ef8c5744e44271bdef8a64eb 490 SUPERFAMILY SSF160424 42 130 3.79E-9 T 14-10-2018 IPR036170 Probable antitoxin YezG superfamily A4R43_30575 0d82dde7ef8c5744e44271bdef8a64eb 490 Pfam PF14021 Tuberculosis necrotizing toxin 405 487 1.4E-15 T 14-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 A4R43_02535 091568ef5071e5649e1670e0dac56590 420 Gene3D G3DSA:3.40.190.10 143 408 7.9E-62 T 14-10-2018 A4R43_02535 091568ef5071e5649e1670e0dac56590 420 Gene3D G3DSA:3.40.190.10 49 348 7.9E-62 T 14-10-2018 A4R43_02535 091568ef5071e5649e1670e0dac56590 420 SUPERFAMILY SSF53850 30 417 3.11E-51 T 14-10-2018 A4R43_02535 091568ef5071e5649e1670e0dac56590 420 Pfam PF13416 Bacterial extracellular solute-binding protein 47 353 4.4E-29 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_39690 6a909ee786de63b539d296e0bc7d2fe5 156 Pfam PF10825 Protein of unknown function (DUF2752) 59 106 1.0E-17 T 14-10-2018 IPR021215 Protein of unknown function DUF2752 A4R43_19120 5fc3282be2a7ce9cbee90579431190e7 218 Gene3D G3DSA:3.40.50.150 1 217 8.1E-76 T 14-10-2018 A4R43_19120 5fc3282be2a7ce9cbee90579431190e7 218 Pfam PF01596 O-methyltransferase 31 215 3.9E-38 T 14-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 A4R43_19120 5fc3282be2a7ce9cbee90579431190e7 218 SUPERFAMILY SSF53335 18 216 1.18E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_22400 6e88407558913236f047d23b4551c227 287 Gene3D G3DSA:1.10.8.10 6 83 4.8E-11 T 14-10-2018 A4R43_22400 6e88407558913236f047d23b4551c227 287 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 17 285 2.1E-39 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A4R43_22400 6e88407558913236f047d23b4551c227 287 Pfam PF05175 Methyltransferase small domain 112 198 3.1E-12 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A4R43_22400 6e88407558913236f047d23b4551c227 287 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 282 2.7E-64 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A4R43_22400 6e88407558913236f047d23b4551c227 287 Gene3D G3DSA:3.40.50.150 86 287 1.4E-49 T 14-10-2018 A4R43_22400 6e88407558913236f047d23b4551c227 287 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 286 38.404 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A4R43_22400 6e88407558913236f047d23b4551c227 287 SUPERFAMILY SSF53335 12 284 7.19E-44 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_22400 6e88407558913236f047d23b4551c227 287 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 191 197 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4R43_26315 514812c190ecd5f18efe2c64c41f540d 152 SUPERFAMILY SSF46785 29 149 2.17E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26315 514812c190ecd5f18efe2c64c41f540d 152 SMART SM00347 34 137 1.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_26315 514812c190ecd5f18efe2c64c41f540d 152 Gene3D G3DSA:1.10.10.10 15 151 1.0E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_26315 514812c190ecd5f18efe2c64c41f540d 152 Pfam PF12802 MarR family 40 99 2.8E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_18185 564987cf6f85b150730ddb4a6d845734 117 Gene3D G3DSA:3.10.180.10 1 117 1.7E-31 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_18185 564987cf6f85b150730ddb4a6d845734 117 SUPERFAMILY SSF54593 1 116 1.36E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_35900 14c87c0c25f8722d6a430a7513617581 447 Gene3D G3DSA:1.20.1250.20 1 212 4.9E-62 T 14-10-2018 A4R43_35900 14c87c0c25f8722d6a430a7513617581 447 SUPERFAMILY SSF103473 8 434 1.44E-46 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_35900 14c87c0c25f8722d6a430a7513617581 447 Pfam PF07690 Major Facilitator Superfamily 40 349 7.3E-22 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_35900 14c87c0c25f8722d6a430a7513617581 447 Gene3D G3DSA:1.20.1250.20 213 437 6.1E-70 T 14-10-2018 A4R43_32630 cc6539d63625cfd1021868b4a46a111d 388 SUPERFAMILY SSF53383 7 386 1.32E-105 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_32630 cc6539d63625cfd1021868b4a46a111d 388 Gene3D G3DSA:3.40.640.10 43 283 4.3E-142 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_32630 cc6539d63625cfd1021868b4a46a111d 388 Pfam PF00155 Aminotransferase class I and II 30 383 8.1E-64 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_32630 cc6539d63625cfd1021868b4a46a111d 388 Gene3D G3DSA:3.90.1150.10 19 383 4.3E-142 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_32630 cc6539d63625cfd1021868b4a46a111d 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 90 110 9.7E-11 T 14-10-2018 A4R43_32630 cc6539d63625cfd1021868b4a46a111d 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 196 219 9.7E-11 T 14-10-2018 A4R43_32630 cc6539d63625cfd1021868b4a46a111d 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 112 133 9.7E-11 T 14-10-2018 A4R43_32630 cc6539d63625cfd1021868b4a46a111d 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 160 184 9.7E-11 T 14-10-2018 A4R43_07020 6b87536d71b20bce2ab7d1d45a573d46 331 Gene3D G3DSA:3.40.50.2300 65 309 1.1E-65 T 14-10-2018 A4R43_07020 6b87536d71b20bce2ab7d1d45a573d46 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 6.2E-9 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_07020 6b87536d71b20bce2ab7d1d45a573d46 331 SMART SM00354 5 74 2.6E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4R43_07020 6b87536d71b20bce2ab7d1d45a573d46 331 Gene3D G3DSA:3.40.50.2300 163 287 1.1E-65 T 14-10-2018 A4R43_07020 6b87536d71b20bce2ab7d1d45a573d46 331 Gene3D G3DSA:1.10.260.40 1 61 3.8E-14 T 14-10-2018 A4R43_07020 6b87536d71b20bce2ab7d1d45a573d46 331 SUPERFAMILY SSF53822 65 328 6.09E-63 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_07020 6b87536d71b20bce2ab7d1d45a573d46 331 SUPERFAMILY SSF47413 5 62 4.69E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_07020 6b87536d71b20bce2ab7d1d45a573d46 331 Pfam PF13377 Periplasmic binding protein-like domain 171 327 1.7E-34 T 14-10-2018 A4R43_02605 8cadb5a9333081f544266b7f8d4f630e 151 Pfam PF01799 [2Fe-2S] binding domain 71 142 1.3E-21 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_02605 8cadb5a9333081f544266b7f8d4f630e 151 SUPERFAMILY SSF47741 71 149 1.31E-25 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_02605 8cadb5a9333081f544266b7f8d4f630e 151 Gene3D G3DSA:1.10.150.120 77 151 3.2E-22 T 14-10-2018 A4R43_02605 8cadb5a9333081f544266b7f8d4f630e 151 Gene3D G3DSA:3.10.20.30 1 74 6.7E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_02605 8cadb5a9333081f544266b7f8d4f630e 151 SUPERFAMILY SSF54292 2 76 5.24E-24 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_02605 8cadb5a9333081f544266b7f8d4f630e 151 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4R43_02605 8cadb5a9333081f544266b7f8d4f630e 151 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 55 1.0E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_16280 bdafb86e228b680600b4e5e740fe1443 68 Pfam PF04149 Domain of unknown function (DUF397) 10 60 2.4E-19 T 14-10-2018 IPR007278 Domain of unknown function DUF397 A4R43_20605 ccde9ea0a4199d1d665044503e1c5e3a 226 Gene3D G3DSA:1.10.3210.10 13 153 1.4E-16 T 14-10-2018 A4R43_20605 ccde9ea0a4199d1d665044503e1c5e3a 226 SUPERFAMILY SSF109604 20 139 9.14E-20 T 14-10-2018 A4R43_27235 961b5befd4c9a67f8c02078a6c346fa3 334 Pfam PF02374 Anion-transporting ATPase 17 176 2.7E-18 T 14-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A4R43_27235 961b5befd4c9a67f8c02078a6c346fa3 334 SUPERFAMILY SSF52540 18 238 4.18E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22575 afb16ff2c3de97e27eaa6030c35f3ca7 67 SMART SM00421 4 61 1.7E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_22575 afb16ff2c3de97e27eaa6030c35f3ca7 67 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 61 1.7E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_22575 afb16ff2c3de97e27eaa6030c35f3ca7 67 Gene3D G3DSA:1.10.10.10 1 67 1.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22575 afb16ff2c3de97e27eaa6030c35f3ca7 67 SUPERFAMILY SSF46894 6 67 5.78E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_41560 93f434a2ac8e95b7d588862ea042cf17 242 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 242 36.552 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A4R43_41560 93f434a2ac8e95b7d588862ea042cf17 242 Pfam PF02654 Cobalamin-5-phosphate synthase 2 238 2.7E-34 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A4R43_00070 6cb14467b08000e5155edab5fadf0328 108 SUPERFAMILY SSF46785 16 104 2.3E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00070 6cb14467b08000e5155edab5fadf0328 108 Pfam PF01638 HxlR-like helix-turn-helix 25 106 1.2E-10 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_00070 6cb14467b08000e5155edab5fadf0328 108 Gene3D G3DSA:1.10.10.10 12 108 1.4E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35135 745d83470cbe5e7f5066b3b8221f4221 547 SUPERFAMILY SSF52096 244 547 2.13E-87 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_35135 745d83470cbe5e7f5066b3b8221f4221 547 Gene3D G3DSA:3.90.226.10 11 276 4.6E-94 T 14-10-2018 A4R43_35135 745d83470cbe5e7f5066b3b8221f4221 547 Gene3D G3DSA:3.90.226.10 284 547 1.9E-91 T 14-10-2018 A4R43_35135 745d83470cbe5e7f5066b3b8221f4221 547 Pfam PF01039 Carboxyl transferase domain 46 545 2.9E-198 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_35135 745d83470cbe5e7f5066b3b8221f4221 547 SUPERFAMILY SSF52096 24 274 3.02E-76 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 PRINTS PR00990 Ribokinase signature 170 185 2.0E-27 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 PRINTS PR00990 Ribokinase signature 105 118 2.0E-27 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 PRINTS PR00990 Ribokinase signature 207 218 2.0E-27 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 PRINTS PR00990 Ribokinase signature 34 53 2.0E-27 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 PRINTS PR00990 Ribokinase signature 7 28 2.0E-27 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 Gene3D G3DSA:3.40.1190.20 1 289 4.3E-90 T 14-10-2018 IPR029056 Ribokinase-like A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 Hamap MF_01987 Ribokinase [rbsK]. 3 289 23.375 T 14-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 SUPERFAMILY SSF53613 1 285 2.18E-75 T 14-10-2018 IPR029056 Ribokinase-like A4R43_30640 8c395a286c3fbaa6aec6cfab92033e6d 289 Pfam PF00294 pfkB family carbohydrate kinase 4 283 1.4E-63 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_24100 ea8919644b179940b95a3b261c45a036 328 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 18 309 3.3E-95 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_24100 ea8919644b179940b95a3b261c45a036 328 Gene3D G3DSA:3.40.50.300 2 246 3.9E-64 T 14-10-2018 A4R43_24100 ea8919644b179940b95a3b261c45a036 328 SMART SM00382 30 214 2.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_24100 ea8919644b179940b95a3b261c45a036 328 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_24100 ea8919644b179940b95a3b261c45a036 328 SUPERFAMILY SSF52540 11 227 2.83E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24100 ea8919644b179940b95a3b261c45a036 328 Pfam PF00005 ABC transporter 22 164 1.5E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_24100 ea8919644b179940b95a3b261c45a036 328 Pfam PF13732 Domain of unknown function (DUF4162) 219 307 1.8E-11 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 A4R43_10095 360eba90fd5974607131c0efa4d11ad9 155 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 20 152 1.9E-18 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 A4R43_15455 53496b3316fe9f18f14f6c467e96bc3e 267 Gene3D G3DSA:1.10.3720.10 11 263 3.0E-69 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_15455 53496b3316fe9f18f14f6c467e96bc3e 267 SUPERFAMILY SSF161098 11 257 1.27E-54 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_15455 53496b3316fe9f18f14f6c467e96bc3e 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 264 5.7E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_15455 53496b3316fe9f18f14f6c467e96bc3e 267 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 33 255 8.3E-73 T 14-10-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0016020|GO:0055085 A4R43_15455 53496b3316fe9f18f14f6c467e96bc3e 267 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 56 259 7.1E-76 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 A4R43_16030 1f23e09db4694d0dd96ec34dafcacb70 181 SMART SM00903 16 161 2.0E-61 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4R43_16030 1f23e09db4694d0dd96ec34dafcacb70 181 Gene3D G3DSA:2.30.110.10 4 173 3.3E-54 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_16030 1f23e09db4694d0dd96ec34dafcacb70 181 Pfam PF01613 Flavin reductase like domain 17 160 2.5E-38 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4R43_16030 1f23e09db4694d0dd96ec34dafcacb70 181 SUPERFAMILY SSF50475 7 163 2.75E-49 T 14-10-2018 A4R43_31270 f06f0564dd5b2d34d48198d1d1a8da41 107 SUPERFAMILY SSF142906 1 104 1.31E-7 T 14-10-2018 IPR038056 YjbR-like superfamily A4R43_31270 f06f0564dd5b2d34d48198d1d1a8da41 107 Pfam PF04237 YjbR 13 100 6.3E-14 T 14-10-2018 IPR007351 Uncharacterised protein YjbR A4R43_40765 51e7f2c6d713effbdcaa3fa222005cdd 263 SUPERFAMILY SSF53335 41 204 9.67E-22 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_40765 51e7f2c6d713effbdcaa3fa222005cdd 263 Pfam PF13489 Methyltransferase domain 46 158 8.8E-10 T 14-10-2018 A4R43_40765 51e7f2c6d713effbdcaa3fa222005cdd 263 Gene3D G3DSA:3.40.50.150 32 209 1.1E-23 T 14-10-2018 A4R43_14845 e4ea00f4917607d17ad0dc686546ec3a 149 Gene3D G3DSA:3.10.180.10 2 136 1.1E-45 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_14845 e4ea00f4917607d17ad0dc686546ec3a 149 SUPERFAMILY SSF54593 1 143 4.43E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_14845 e4ea00f4917607d17ad0dc686546ec3a 149 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 130 1.2E-12 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_33265 24a3003d5868ffb9038d832a9793a8b3 263 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 66 243 3.9E-41 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 A4R43_33265 24a3003d5868ffb9038d832a9793a8b3 263 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 70 241 1.6E-53 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 A4R43_01335 a6f05a7fb67e8406bb30f343e396e270 404 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 160 341 5.7E-19 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 A4R43_00730 5b8f4a6390b055238e7621a26aa84377 111 Pfam PF12973 ChrR Cupin-like domain 25 106 2.7E-16 T 14-10-2018 IPR025979 ChrR-like cupin domain A4R43_00730 5b8f4a6390b055238e7621a26aa84377 111 SUPERFAMILY SSF51182 12 107 5.4E-19 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_00730 5b8f4a6390b055238e7621a26aa84377 111 Gene3D G3DSA:2.60.120.10 7 110 1.4E-23 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_23185 a0e7eb19c50f097cebec00625d745945 470 Pfam PF06974 Protein of unknown function (DUF1298) 320 466 1.2E-21 T 14-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_23185 a0e7eb19c50f097cebec00625d745945 470 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 5 468 1.0E-136 T 14-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_23185 a0e7eb19c50f097cebec00625d745945 470 SUPERFAMILY SSF52777 36 149 9.0E-6 T 14-10-2018 A4R43_23185 a0e7eb19c50f097cebec00625d745945 470 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 273 2.8E-71 T 14-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_22100 2239bbe0d8a6f6919113170c4b9a1d52 160 PIRSF PIRSF021697 1 159 1.8E-41 T 14-10-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane A4R43_22100 2239bbe0d8a6f6919113170c4b9a1d52 160 Pfam PF06271 RDD family 44 136 3.1E-7 T 14-10-2018 IPR010432 RDD A4R43_28420 bf5229e10116cb84de9b652285470937 227 PIRSF PIRSF003170 2 219 4.8E-30 T 14-10-2018 IPR026285 TenA_E protein A4R43_28420 bf5229e10116cb84de9b652285470937 227 SUPERFAMILY SSF48613 3 215 1.78E-68 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_28420 bf5229e10116cb84de9b652285470937 227 Pfam PF03070 TENA/THI-4/PQQC family 11 217 1.3E-45 T 14-10-2018 IPR004305 Thiaminase-2/PQQC A4R43_28420 bf5229e10116cb84de9b652285470937 227 Gene3D G3DSA:1.20.910.10 2 226 1.0E-72 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_28420 bf5229e10116cb84de9b652285470937 227 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 17 217 2.9E-44 T 14-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 A4R43_10280 9eb9b303a0bc913f73d782f8fce2481c 300 Pfam PF07859 alpha/beta hydrolase fold 80 280 5.1E-34 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_10280 9eb9b303a0bc913f73d782f8fce2481c 300 SUPERFAMILY SSF53474 25 292 4.22E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_10280 9eb9b303a0bc913f73d782f8fce2481c 300 Gene3D G3DSA:3.40.50.1820 13 300 3.3E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16535 b9a04df7a1912200e6f5bde4f14b920c 418 SUPERFAMILY SSF53335 140 405 8.67E-74 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_16535 b9a04df7a1912200e6f5bde4f14b920c 418 PIRSF PIRSF003085 6 417 8.8E-114 T 14-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 A4R43_16535 b9a04df7a1912200e6f5bde4f14b920c 418 Pfam PF02353 Mycolic acid cyclopropane synthetase 131 399 5.3E-82 T 14-10-2018 A4R43_16535 b9a04df7a1912200e6f5bde4f14b920c 418 Gene3D G3DSA:3.40.50.150 138 408 6.9E-95 T 14-10-2018 A4R43_26670 0e6b5b1c018a7b01dc19efb549beaae0 274 Gene3D G3DSA:3.40.50.300 2 254 1.9E-54 T 14-10-2018 A4R43_26670 0e6b5b1c018a7b01dc19efb549beaae0 274 Pfam PF00005 ABC transporter 26 170 5.9E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_26670 0e6b5b1c018a7b01dc19efb549beaae0 274 SUPERFAMILY SSF52540 7 234 2.66E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26670 0e6b5b1c018a7b01dc19efb549beaae0 274 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_26670 0e6b5b1c018a7b01dc19efb549beaae0 274 SMART SM00382 33 220 5.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_38435 c3bf9f901d3cf3dcf45e7d6a26c84206 619 Gene3D G3DSA:3.40.50.300 369 615 2.4E-87 T 14-10-2018 A4R43_38435 c3bf9f901d3cf3dcf45e7d6a26c84206 619 Pfam PF00664 ABC transporter transmembrane region 21 328 2.0E-50 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4R43_38435 c3bf9f901d3cf3dcf45e7d6a26c84206 619 Pfam PF00005 ABC transporter 392 540 1.7E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_38435 c3bf9f901d3cf3dcf45e7d6a26c84206 619 SMART SM00382 400 586 1.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_38435 c3bf9f901d3cf3dcf45e7d6a26c84206 619 ProSitePatterns PS00211 ABC transporters family signature. 512 526 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_38435 c3bf9f901d3cf3dcf45e7d6a26c84206 619 SUPERFAMILY SSF52540 367 608 1.78E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38435 c3bf9f901d3cf3dcf45e7d6a26c84206 619 SUPERFAMILY SSF90123 4 365 4.05E-77 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4R43_34095 0faacda3533bfa0ce0ae2001f58a9b25 150 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 2.0E-62 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_34095 0faacda3533bfa0ce0ae2001f58a9b25 150 Pfam PF00572 Ribosomal protein L13 15 138 1.2E-57 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4R43_34095 0faacda3533bfa0ce0ae2001f58a9b25 150 PIRSF PIRSF002181 4 150 1.1E-50 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4R43_34095 0faacda3533bfa0ce0ae2001f58a9b25 150 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 14-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A4R43_34095 0faacda3533bfa0ce0ae2001f58a9b25 150 SUPERFAMILY SSF52161 4 143 7.46E-61 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_34095 0faacda3533bfa0ce0ae2001f58a9b25 150 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 29.79 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4R43_34095 0faacda3533bfa0ce0ae2001f58a9b25 150 Gene3D G3DSA:3.90.1180.10 1 142 5.5E-62 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_02190 96f42e59485dafab05a33247a33c1a1d 70 SMART SM00923 1 49 1.6E-17 T 14-10-2018 IPR005153 MbtH-like domain A4R43_02190 96f42e59485dafab05a33247a33c1a1d 70 Gene3D G3DSA:3.90.820.10 1 68 7.7E-27 T 14-10-2018 A4R43_02190 96f42e59485dafab05a33247a33c1a1d 70 SUPERFAMILY SSF160582 3 65 6.67E-24 T 14-10-2018 IPR038020 MbtH-like domain superfamily A4R43_02190 96f42e59485dafab05a33247a33c1a1d 70 Pfam PF03621 MbtH-like protein 2 47 5.2E-18 T 14-10-2018 IPR005153 MbtH-like domain A4R43_20825 15fe730bf2e42633d06dd4e23afc39e3 198 Gene3D G3DSA:3.40.430.10 5 195 1.0E-40 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_20825 15fe730bf2e42633d06dd4e23afc39e3 198 Pfam PF01872 RibD C-terminal domain 5 191 5.8E-25 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_20825 15fe730bf2e42633d06dd4e23afc39e3 198 SUPERFAMILY SSF53597 5 197 4.58E-28 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_17080 6bec175f888b9f162b026b19f38b80f2 509 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 152 177 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site A4R43_17080 6bec175f888b9f162b026b19f38b80f2 509 Gene3D G3DSA:1.20.1730.10 23 495 1.3E-77 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_17080 6bec175f888b9f162b026b19f38b80f2 509 Pfam PF00474 Sodium:solute symporter family 33 431 3.7E-33 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_29785 2d0f1ae3f9e1a7aa2763aa5f9bbb38b9 147 SUPERFAMILY SSF50475 1 145 6.38E-45 T 14-10-2018 A4R43_29785 2d0f1ae3f9e1a7aa2763aa5f9bbb38b9 147 SMART SM00903 1 144 8.1E-58 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4R43_29785 2d0f1ae3f9e1a7aa2763aa5f9bbb38b9 147 Pfam PF01613 Flavin reductase like domain 1 145 3.7E-37 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4R43_29785 2d0f1ae3f9e1a7aa2763aa5f9bbb38b9 147 Gene3D G3DSA:2.30.110.10 1 147 6.5E-47 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_02910 7ce54d761bde951fbc1a4aa0b59f8b4a 121 SUPERFAMILY SSF46785 1 116 1.22E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02910 7ce54d761bde951fbc1a4aa0b59f8b4a 121 Gene3D G3DSA:1.10.10.10 1 69 9.6E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02910 7ce54d761bde951fbc1a4aa0b59f8b4a 121 Pfam PF03965 Penicillinase repressor 4 114 6.2E-28 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A4R43_02910 7ce54d761bde951fbc1a4aa0b59f8b4a 121 PIRSF PIRSF019455 1 121 1.6E-22 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A4R43_40070 de1850eb151628e02ed7203493ccca58 264 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 250 1.0E-64 T 14-10-2018 A4R43_40070 de1850eb151628e02ed7203493ccca58 264 SUPERFAMILY SSF51621 9 257 1.03E-53 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_40070 de1850eb151628e02ed7203493ccca58 264 Gene3D G3DSA:3.20.20.60 7 261 1.1E-62 T 14-10-2018 A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 8.2E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.2E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 183 0.0015 T 14-10-2018 A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 244 1.2E-62 T 14-10-2018 A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 SUPERFAMILY SSF51735 5 245 2.1E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 Gene3D G3DSA:3.40.50.720 1 249 7.0E-77 T 14-10-2018 A4R43_37220 b0be82dac65acae7ce75454823883a7e 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_14020 84fea228db140c381448f94cf674c56d 218 Pfam PF02080 TrkA-C domain 149 216 8.1E-15 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4R43_14020 84fea228db140c381448f94cf674c56d 218 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 8.4E-7 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4R43_14020 84fea228db140c381448f94cf674c56d 218 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 8.4E-7 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4R43_14020 84fea228db140c381448f94cf674c56d 218 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 8.4E-7 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4R43_14020 84fea228db140c381448f94cf674c56d 218 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 8.4E-7 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4R43_14020 84fea228db140c381448f94cf674c56d 218 Gene3D G3DSA:3.40.50.720 2 133 4.9E-31 T 14-10-2018 A4R43_14020 84fea228db140c381448f94cf674c56d 218 Gene3D G3DSA:3.30.70.1450 136 216 5.1E-18 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_14020 84fea228db140c381448f94cf674c56d 218 SUPERFAMILY SSF116726 133 216 1.31E-14 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A4R43_14020 84fea228db140c381448f94cf674c56d 218 SUPERFAMILY SSF51735 1 144 4.68E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_14020 84fea228db140c381448f94cf674c56d 218 Pfam PF02254 TrkA-N domain 3 118 8.3E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4R43_12695 0a2eb9613810e74dbd67a0b449063b00 283 SUPERFAMILY SSF48179 185 282 2.81E-25 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_12695 0a2eb9613810e74dbd67a0b449063b00 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 1.5E-23 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_12695 0a2eb9613810e74dbd67a0b449063b00 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 4.0E-46 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_12695 0a2eb9613810e74dbd67a0b449063b00 283 Gene3D G3DSA:1.10.1040.10 188 283 9.4E-24 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_12695 0a2eb9613810e74dbd67a0b449063b00 283 SUPERFAMILY SSF51735 2 185 3.73E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_12695 0a2eb9613810e74dbd67a0b449063b00 283 Gene3D G3DSA:3.40.50.720 1 187 1.6E-49 T 14-10-2018 A4R43_12695 0a2eb9613810e74dbd67a0b449063b00 283 PIRSF PIRSF000105 1 283 1.5E-66 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A4R43_08415 a796d534c5b218d01c843725fcdddc1f 231 SUPERFAMILY SSF46785 7 90 1.55E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08415 a796d534c5b218d01c843725fcdddc1f 231 Pfam PF12840 Helix-turn-helix domain 12 69 3.8E-10 T 14-10-2018 A4R43_08415 a796d534c5b218d01c843725fcdddc1f 231 Gene3D G3DSA:1.10.10.10 2 92 1.0E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08415 a796d534c5b218d01c843725fcdddc1f 231 SMART SM00418 12 89 2.5E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_07515 b69095005a588fb2b9d704bec8c5e9c9 351 Gene3D G3DSA:3.40.50.2000 2 154 3.2E-7 T 14-10-2018 A4R43_07515 b69095005a588fb2b9d704bec8c5e9c9 351 SUPERFAMILY SSF53756 3 334 1.07E-68 T 14-10-2018 A4R43_07515 b69095005a588fb2b9d704bec8c5e9c9 351 Gene3D G3DSA:3.40.50.2000 169 338 1.0E-42 T 14-10-2018 A4R43_07515 b69095005a588fb2b9d704bec8c5e9c9 351 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 124 311 1.8E-27 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 A4R43_29600 7dfa6c30fc73a5ed861f5e52f23c2c8c 185 Pfam PF03781 Sulfatase-modifying factor enzyme 1 43 183 2.1E-21 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A4R43_29600 7dfa6c30fc73a5ed861f5e52f23c2c8c 185 Gene3D G3DSA:3.90.1580.10 4 184 2.4E-32 T 14-10-2018 A4R43_29600 7dfa6c30fc73a5ed861f5e52f23c2c8c 185 SUPERFAMILY SSF56436 4 183 1.2E-39 T 14-10-2018 IPR016187 C-type lectin fold A4R43_22565 29f4626ad3a59dc82edce2b29bf3aa2c 359 Gene3D G3DSA:3.40.50.2300 178 315 6.4E-85 T 14-10-2018 A4R43_22565 29f4626ad3a59dc82edce2b29bf3aa2c 359 Gene3D G3DSA:3.40.50.2300 75 332 6.4E-85 T 14-10-2018 A4R43_22565 29f4626ad3a59dc82edce2b29bf3aa2c 359 SUPERFAMILY SSF53822 71 353 3.61E-70 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_22565 29f4626ad3a59dc82edce2b29bf3aa2c 359 Pfam PF13407 Periplasmic binding protein domain 74 333 4.7E-54 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 TIGRFAM TIGR00593 pola: DNA polymerase I 16 902 7.5E-302 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Gene3D G3DSA:1.10.150.20 187 259 1.3E-94 T 14-10-2018 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Gene3D G3DSA:3.30.70.370 638 899 5.5E-101 T 14-10-2018 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Gene3D G3DSA:3.40.50.1010 16 290 1.3E-94 T 14-10-2018 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 SUPERFAMILY SSF56672 500 902 1.02E-134 T 14-10-2018 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 15 183 2.8E-53 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 185 278 2.4E-27 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Gene3D G3DSA:1.10.150.20 684 827 5.5E-101 T 14-10-2018 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 SMART SM00482 660 867 2.2E-105 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Gene3D G3DSA:3.30.420.10 329 516 3.8E-29 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 766 777 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 629 651 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 675 698 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 718 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 850 863 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 652 667 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 729 754 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 820 836 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 788 799 7.9E-73 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 SUPERFAMILY SSF47807 184 297 1.14E-30 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 SMART SM00279 186 221 1.6E-14 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Gene3D G3DSA:1.20.1060.10 518 632 6.6E-32 T 14-10-2018 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 SUPERFAMILY SSF88723 9 183 1.82E-52 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 SUPERFAMILY SSF53098 320 494 2.12E-27 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 SMART SM00474 315 493 0.0017 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 SMART SM00475 14 274 7.2E-134 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A4R43_14855 4196818f84762bd02be64c41baf56fc0 904 Pfam PF00476 DNA polymerase family A 525 900 1.2E-139 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_09575 e5e08b09f9fa4dcd3aaf9514a3991f82 297 Gene3D G3DSA:1.10.10.10 1 85 6.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09575 e5e08b09f9fa4dcd3aaf9514a3991f82 297 Gene3D G3DSA:3.40.190.10 169 268 1.3E-56 T 14-10-2018 A4R43_09575 e5e08b09f9fa4dcd3aaf9514a3991f82 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.1E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_09575 e5e08b09f9fa4dcd3aaf9514a3991f82 297 SUPERFAMILY SSF46785 4 84 2.72E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09575 e5e08b09f9fa4dcd3aaf9514a3991f82 297 SUPERFAMILY SSF53850 92 295 4.19E-41 T 14-10-2018 A4R43_09575 e5e08b09f9fa4dcd3aaf9514a3991f82 297 Pfam PF03466 LysR substrate binding domain 93 295 6.8E-28 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_09575 e5e08b09f9fa4dcd3aaf9514a3991f82 297 Gene3D G3DSA:3.40.190.10 93 292 1.3E-56 T 14-10-2018 A4R43_07625 2658f40a0b3d80ad2fab1f27d8ae8292 190 Gene3D G3DSA:1.10.357.10 4 190 3.9E-36 T 14-10-2018 A4R43_07625 2658f40a0b3d80ad2fab1f27d8ae8292 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07625 2658f40a0b3d80ad2fab1f27d8ae8292 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07625 2658f40a0b3d80ad2fab1f27d8ae8292 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 2.4E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07625 2658f40a0b3d80ad2fab1f27d8ae8292 190 SUPERFAMILY SSF46689 5 73 1.9E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_16810 3de1e13caf228cfae9592737bc7a54a2 158 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 2.5E-49 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A4R43_16810 3de1e13caf228cfae9592737bc7a54a2 158 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 78.452 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A4R43_16810 3de1e13caf228cfae9592737bc7a54a2 158 Pfam PF03477 ATP cone domain 47 132 2.7E-14 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A4R43_38320 53304f371fb37d81c8bd13df7433d433 139 Gene3D G3DSA:3.30.70.1060 1 117 1.0E-28 T 14-10-2018 A4R43_38320 53304f371fb37d81c8bd13df7433d433 139 SUPERFAMILY SSF54909 1 118 4.29E-29 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_38320 53304f371fb37d81c8bd13df7433d433 139 Pfam PF03795 YCII-related domain 1 114 4.3E-21 T 14-10-2018 IPR005545 YCII-related A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 SUPERFAMILY SSF46894 137 202 1.19E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 SUPERFAMILY SSF52172 4 124 1.37E-20 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 Pfam PF00072 Response regulator receiver domain 7 114 3.3E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 SMART SM00421 147 204 1.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 Gene3D G3DSA:3.40.50.12740 4 204 4.1E-41 T 14-10-2018 A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 8.9E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 8.9E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 8.9E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 SMART SM00448 4 118 3.8E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_06950 48fbfbe92d0811819a3231854740e81c 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 202 7.4E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_10090 970eeeab5bda0680cdfff8ed6be5a751 502 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 19 437 1.4E-147 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 SMART SM00487 50 237 4.5E-26 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 Gene3D G3DSA:3.40.50.300 231 401 2.9E-57 T 14-10-2018 A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 Gene3D G3DSA:3.40.50.300 7 230 1.2E-74 T 14-10-2018 A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 603 679 1.4E-18 T 14-10-2018 IPR011709 Domain of unknown function DUF1605 A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 SUPERFAMILY SSF52540 52 588 1.35E-108 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 SMART SM00490 285 385 3.1E-14 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 Gene3D G3DSA:1.20.120.1080 430 530 4.8E-17 T 14-10-2018 A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 Pfam PF00271 Helicase conserved C-terminal domain 265 384 1.9E-10 T 14-10-2018 IPR001650 Helicase, C-terminal A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 Pfam PF11898 Domain of unknown function (DUF3418) 693 1275 3.2E-235 T 14-10-2018 IPR024590 RNA helicase HrpA, C-terminal A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 SMART SM00382 70 365 4.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 2 1275 0.0 T 14-10-2018 IPR010222 RNA helicase HrpA GO:0004004 A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 Pfam PF00270 DEAD/DEAH box helicase 67 211 5.8E-6 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 Pfam PF04408 Helicase associated domain (HA2) 447 538 7.3E-16 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 A4R43_19060 8eef7ad2396034286a5ee096526878d4 1282 SMART SM00847 445 540 7.0E-36 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 A4R43_35975 f85eda4f6037568cc316f46765bbda32 316 Pfam PF04228 Putative neutral zinc metallopeptidase 124 308 4.0E-12 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative A4R43_34675 90caee95fa14090a2083bda41e8528f6 416 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 81 305 4.3E-41 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A4R43_34675 90caee95fa14090a2083bda41e8528f6 416 Gene3D G3DSA:3.40.710.10 54 341 1.2E-85 T 14-10-2018 A4R43_34675 90caee95fa14090a2083bda41e8528f6 416 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 163 180 7.3E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4R43_34675 90caee95fa14090a2083bda41e8528f6 416 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 189 202 7.3E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4R43_34675 90caee95fa14090a2083bda41e8528f6 416 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 126 7.3E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4R43_34675 90caee95fa14090a2083bda41e8528f6 416 SUPERFAMILY SSF56601 8 325 2.9E-52 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_24095 3fbc154c3142408a2b6456d773374ca8 193 Gene3D G3DSA:1.10.10.10 3 92 1.9E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_24095 3fbc154c3142408a2b6456d773374ca8 193 SUPERFAMILY SSF46785 4 174 2.53E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_24095 3fbc154c3142408a2b6456d773374ca8 193 Pfam PF03551 Transcriptional regulator PadR-like family 8 82 2.2E-12 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_05380 64a44ece2da4e2a62af92e11b3596aea 68 SUPERFAMILY SSF160582 5 55 1.44E-13 T 14-10-2018 IPR038020 MbtH-like domain superfamily A4R43_05380 64a44ece2da4e2a62af92e11b3596aea 68 SMART SM00923 3 53 4.1E-9 T 14-10-2018 IPR005153 MbtH-like domain A4R43_05380 64a44ece2da4e2a62af92e11b3596aea 68 Gene3D G3DSA:3.90.820.10 1 61 2.3E-14 T 14-10-2018 A4R43_05380 64a44ece2da4e2a62af92e11b3596aea 68 Pfam PF03621 MbtH-like protein 6 52 2.3E-14 T 14-10-2018 IPR005153 MbtH-like domain A4R43_20885 0bd9559f9cdf846435e63eb71021a41a 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-10 T 14-10-2018 A4R43_20885 0bd9559f9cdf846435e63eb71021a41a 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 91 109 1.1E-10 T 14-10-2018 A4R43_20885 0bd9559f9cdf846435e63eb71021a41a 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.1E-10 T 14-10-2018 A4R43_20885 0bd9559f9cdf846435e63eb71021a41a 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 268 1.1E-10 T 14-10-2018 A4R43_20885 0bd9559f9cdf846435e63eb71021a41a 354 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 283 1.2E-36 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_20885 0bd9559f9cdf846435e63eb71021a41a 354 SUPERFAMILY SSF51905 2 289 1.19E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_20885 0bd9559f9cdf846435e63eb71021a41a 354 Gene3D G3DSA:3.50.50.100 2 342 1.7E-51 T 14-10-2018 A4R43_03435 f9a91ddd9afef33c7613c23f462d3c90 306 Pfam PF01636 Phosphotransferase enzyme family 45 216 1.9E-6 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_03435 f9a91ddd9afef33c7613c23f462d3c90 306 SUPERFAMILY SSF56112 7 291 7.99E-18 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_16370 71d52476a22991ba15d8e8b86d573eb7 379 Gene3D G3DSA:3.40.50.300 1 299 3.0E-77 T 14-10-2018 A4R43_16370 71d52476a22991ba15d8e8b86d573eb7 379 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 5 285 1.2E-52 T 14-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 A4R43_16370 71d52476a22991ba15d8e8b86d573eb7 379 Gene3D G3DSA:2.60.40.790 305 376 5.6E-12 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_16370 71d52476a22991ba15d8e8b86d573eb7 379 SUPERFAMILY SSF52540 2 230 1.37E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16370 71d52476a22991ba15d8e8b86d573eb7 379 Pfam PF02374 Anion-transporting ATPase 2 288 2.3E-59 T 14-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A4R43_27745 7323f0a87bf9f81f67fdb1ca2a90b105 260 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 233 4.3E-28 T 14-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 SMART SM00895 92 214 1.2E-23 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 Pfam PF07729 FCD domain 92 213 8.7E-27 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 SUPERFAMILY SSF46785 1 70 3.5E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 8.1E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 8.1E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 Gene3D G3DSA:1.10.10.10 2 70 6.6E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 5.1E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 Gene3D G3DSA:1.20.120.530 88 227 2.9E-32 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 SUPERFAMILY SSF48008 89 223 9.68E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_38180 2ba0605e15f38dbeec88e59ce105bebd 230 SMART SM00345 7 66 7.7E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 SUPERFAMILY SSF49478 690 759 2.24E-11 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 28 512 2.5E-78 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 SUPERFAMILY SSF49464 775 859 2.63E-11 T 14-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 SUPERFAMILY SSF103473 12 514 9.94E-70 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 Gene3D G3DSA:2.60.40.1120 606 685 2.2E-7 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 SUPERFAMILY SSF49464 607 683 1.37E-9 T 14-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 Pfam PF07690 Major Facilitator Superfamily 34 431 4.9E-53 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 Pfam PF13620 Carboxypeptidase regulatory-like domain 607 684 7.0E-12 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 Pfam PF13620 Carboxypeptidase regulatory-like domain 775 851 3.1E-12 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 Pfam PF13620 Carboxypeptidase regulatory-like domain 690 769 2.1E-12 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 PRINTS PR01036 Tetracycline resistance protein TetB signature 152 176 9.7E-5 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 PRINTS PR01036 Tetracycline resistance protein TetB signature 32 56 9.7E-5 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 PRINTS PR01036 Tetracycline resistance protein TetB signature 122 142 9.7E-5 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 Gene3D G3DSA:1.20.1720.10 29 237 1.2E-49 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 Gene3D G3DSA:2.60.40.1120 775 852 4.5E-9 T 14-10-2018 A4R43_31545 8b184337cd03c5792bfb1ac42cc846c1 865 Gene3D G3DSA:2.60.40.1120 690 770 7.7E-10 T 14-10-2018 A4R43_17145 c910292bd79a32cbc76fa5610c1b3682 171 Gene3D G3DSA:3.40.630.30 5 170 5.9E-46 T 14-10-2018 A4R43_17145 c910292bd79a32cbc76fa5610c1b3682 171 SUPERFAMILY SSF55729 9 134 1.17E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_17145 c910292bd79a32cbc76fa5610c1b3682 171 Pfam PF00583 Acetyltransferase (GNAT) family 43 128 2.8E-9 T 14-10-2018 IPR000182 GNAT domain A4R43_33630 12639678cbf5b0cba13d70977a7d8a59 404 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 301 2.2E-69 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33630 12639678cbf5b0cba13d70977a7d8a59 404 Pfam PF02470 MlaD protein 40 116 1.9E-17 T 14-10-2018 IPR003399 Mce/MlaD A4R43_33630 12639678cbf5b0cba13d70977a7d8a59 404 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 160 282 1.3E-8 T 14-10-2018 IPR024516 Mammalian cell entry, C-terminal A4R43_36345 1eedc987a38fcc9a04b78d52b8f1856d 211 SUPERFAMILY SSF144091 30 203 7.06E-28 T 14-10-2018 A4R43_36345 1eedc987a38fcc9a04b78d52b8f1856d 211 Pfam PF01694 Rhomboid family 65 201 1.2E-20 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4R43_36345 1eedc987a38fcc9a04b78d52b8f1856d 211 Gene3D G3DSA:1.20.1540.10 25 205 9.7E-14 T 14-10-2018 IPR035952 Rhomboid-like superfamily A4R43_34960 2a4c8ae4af3f6e07319940a9d1453183 650 SMART SM00220 6 264 4.4E-61 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_34960 2a4c8ae4af3f6e07319940a9d1453183 650 SUPERFAMILY SSF56112 2 268 1.48E-67 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_34960 2a4c8ae4af3f6e07319940a9d1453183 650 Gene3D G3DSA:3.30.200.20 1 89 8.3E-26 T 14-10-2018 A4R43_34960 2a4c8ae4af3f6e07319940a9d1453183 650 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_34960 2a4c8ae4af3f6e07319940a9d1453183 650 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 12 35 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_34960 2a4c8ae4af3f6e07319940a9d1453183 650 Gene3D G3DSA:1.10.510.10 93 272 3.0E-44 T 14-10-2018 A4R43_34960 2a4c8ae4af3f6e07319940a9d1453183 650 Pfam PF00069 Protein kinase domain 7 256 8.8E-48 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_13550 c694d4716739fe6d69ded62d10fadb91 346 SUPERFAMILY SSF54593 3 283 3.39E-41 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_13550 c694d4716739fe6d69ded62d10fadb91 346 Gene3D G3DSA:3.10.180.10 1 143 1.5E-50 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_13550 c694d4716739fe6d69ded62d10fadb91 346 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 120 1.4E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_13550 c694d4716739fe6d69ded62d10fadb91 346 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 144 260 3.9E-13 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_13550 c694d4716739fe6d69ded62d10fadb91 346 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 6 301 6.2E-125 T 14-10-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type A4R43_13550 c694d4716739fe6d69ded62d10fadb91 346 Gene3D G3DSA:3.10.180.10 144 282 3.5E-40 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_13550 c694d4716739fe6d69ded62d10fadb91 346 Gene3D G3DSA:4.10.1270.10 283 346 3.1E-29 T 14-10-2018 A4R43_13550 c694d4716739fe6d69ded62d10fadb91 346 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 238 259 - T 14-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 A4R43_10000 4a646aefae850fe38321a281527e7991 139 Gene3D G3DSA:3.10.180.10 6 137 1.3E-43 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_10000 4a646aefae850fe38321a281527e7991 139 SUPERFAMILY SSF54593 14 137 1.17E-15 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 Gene3D G3DSA:3.20.20.80 30 249 1.0E-52 T 14-10-2018 A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 Pfam PF00232 Glycosyl hydrolase family 1 34 239 1.2E-37 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 Pfam PF00232 Glycosyl hydrolase family 1 282 404 1.7E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 SUPERFAMILY SSF51445 34 412 4.35E-93 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 330 341 5.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 374 386 5.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 351 368 5.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 312 320 5.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 259 273 5.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_10080 66d8455e3aacfdcbe6ee320c256df9b8 440 Gene3D G3DSA:3.20.20.80 250 415 6.7E-33 T 14-10-2018 A4R43_02795 6e5707d23bb0729110fa1f7a89e2e160 584 Pfam PF00041 Fibronectin type III domain 400 476 2.9E-10 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_02795 6e5707d23bb0729110fa1f7a89e2e160 584 Gene3D G3DSA:2.60.40.10 392 485 5.0E-15 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_02795 6e5707d23bb0729110fa1f7a89e2e160 584 SUPERFAMILY SSF81995 344 405 1.49E-6 T 14-10-2018 A4R43_02795 6e5707d23bb0729110fa1f7a89e2e160 584 SMART SM00060 398 476 5.7E-9 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 A4R43_02795 6e5707d23bb0729110fa1f7a89e2e160 584 SUPERFAMILY SSF49265 394 477 1.41E-15 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A4R43_04120 4bb782cc76bbf7585d1537d90aaa1a27 274 Pfam PF13649 Methyltransferase domain 45 131 7.9E-17 T 14-10-2018 A4R43_04120 4bb782cc76bbf7585d1537d90aaa1a27 274 Gene3D G3DSA:3.40.50.150 10 178 1.8E-30 T 14-10-2018 A4R43_04120 4bb782cc76bbf7585d1537d90aaa1a27 274 SUPERFAMILY SSF53335 7 143 1.78E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_23800 af34805d4a7e49ce9439005e2898de7c 159 SUPERFAMILY SSF50475 10 147 1.34E-19 T 14-10-2018 A4R43_23800 af34805d4a7e49ce9439005e2898de7c 159 Gene3D G3DSA:2.30.110.10 8 151 3.2E-23 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_23800 af34805d4a7e49ce9439005e2898de7c 159 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 91 1.6E-5 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_00200 a85176489d0135882ffc6413f5a86338 315 Pfam PF00544 Pectate lyase 85 248 5.7E-39 T 14-10-2018 IPR002022 Pectate lyase A4R43_00200 a85176489d0135882ffc6413f5a86338 315 Gene3D G3DSA:2.160.20.10 33 315 3.4E-97 T 14-10-2018 IPR012334 Pectin lyase fold A4R43_00200 a85176489d0135882ffc6413f5a86338 315 SMART SM00710 136 158 20.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_00200 a85176489d0135882ffc6413f5a86338 315 SMART SM00710 215 237 6800.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_00200 a85176489d0135882ffc6413f5a86338 315 SMART SM00710 112 134 17.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat A4R43_00200 a85176489d0135882ffc6413f5a86338 315 SMART SM00656 48 254 1.3E-53 T 14-10-2018 IPR002022 Pectate lyase A4R43_00200 a85176489d0135882ffc6413f5a86338 315 SUPERFAMILY SSF51126 34 314 1.52E-78 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_27225 2eb59141ca6bd90e8d61f30ed7804cef 313 Gene3D G3DSA:3.40.50.1820 53 308 7.8E-68 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27225 2eb59141ca6bd90e8d61f30ed7804cef 313 Pfam PF01674 Lipase (class 2) 67 278 1.1E-13 T 14-10-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 A4R43_27225 2eb59141ca6bd90e8d61f30ed7804cef 313 SUPERFAMILY SSF53474 61 261 3.76E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_37610 9f9a5135563c883207ae8be814da0a79 245 SUPERFAMILY SSF53790 3 242 3.79E-36 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4R43_37610 9f9a5135563c883207ae8be814da0a79 245 PIRSF PIRSF036525 1 245 7.0E-100 T 14-10-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 A4R43_37610 9f9a5135563c883207ae8be814da0a79 245 Gene3D G3DSA:3.30.950.10 140 245 3.2E-43 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4R43_37610 9f9a5135563c883207ae8be814da0a79 245 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 2 242 2.2E-101 T 14-10-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 A4R43_37610 9f9a5135563c883207ae8be814da0a79 245 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 217 1.2E-30 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4R43_37610 9f9a5135563c883207ae8be814da0a79 245 Gene3D G3DSA:3.40.1010.10 1 139 7.6E-42 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4R43_25115 18848313c1ec8910290096c258e9db81 196 SMART SM00255 5 162 0.002 T 14-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 A4R43_25115 18848313c1ec8910290096c258e9db81 196 Pfam PF13676 TIR domain 9 95 4.1E-9 T 14-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 A4R43_25115 18848313c1ec8910290096c258e9db81 196 SUPERFAMILY SSF52200 2 121 9.29E-18 T 14-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily A4R43_25115 18848313c1ec8910290096c258e9db81 196 Gene3D G3DSA:3.40.50.10140 1 166 4.2E-23 T 14-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily A4R43_32865 11da8d689d188295be3f93dc2e49e9f9 226 SUPERFAMILY SSF88946 39 137 3.1E-24 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_32865 11da8d689d188295be3f93dc2e49e9f9 226 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 54 220 1.0E-25 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_32865 11da8d689d188295be3f93dc2e49e9f9 226 Gene3D G3DSA:1.10.10.10 151 222 8.8E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32865 11da8d689d188295be3f93dc2e49e9f9 226 Pfam PF04542 Sigma-70 region 2 58 125 1.1E-14 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_32865 11da8d689d188295be3f93dc2e49e9f9 226 Pfam PF08281 Sigma-70, region 4 167 217 1.7E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_32865 11da8d689d188295be3f93dc2e49e9f9 226 SUPERFAMILY SSF88659 154 221 3.36E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_32865 11da8d689d188295be3f93dc2e49e9f9 226 Gene3D G3DSA:1.10.1740.10 30 122 3.1E-23 T 14-10-2018 A4R43_17980 abd2810aeb92c6eba4e9fb876f659be7 511 SUPERFAMILY SSF103473 7 490 3.92E-63 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_17980 abd2810aeb92c6eba4e9fb876f659be7 511 Gene3D G3DSA:1.20.1720.10 12 217 7.6E-43 T 14-10-2018 A4R43_17980 abd2810aeb92c6eba4e9fb876f659be7 511 Pfam PF07690 Major Facilitator Superfamily 13 408 1.1E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_17980 abd2810aeb92c6eba4e9fb876f659be7 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 1.9E-10 T 14-10-2018 A4R43_17980 abd2810aeb92c6eba4e9fb876f659be7 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 1.9E-10 T 14-10-2018 A4R43_17980 abd2810aeb92c6eba4e9fb876f659be7 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.9E-10 T 14-10-2018 A4R43_17980 abd2810aeb92c6eba4e9fb876f659be7 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 1.9E-10 T 14-10-2018 A4R43_04545 2bad9107339e0336a7210f9be3f899fa 276 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 1 263 9.4E-66 T 14-10-2018 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+1.1.1.25+4.2.1.10+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_04545 2bad9107339e0336a7210f9be3f899fa 276 SUPERFAMILY SSF51735 96 266 1.93E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04545 2bad9107339e0336a7210f9be3f899fa 276 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 120 204 1.3E-5 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A4R43_04545 2bad9107339e0336a7210f9be3f899fa 276 Gene3D G3DSA:3.40.50.720 96 241 9.6E-81 T 14-10-2018 A4R43_04545 2bad9107339e0336a7210f9be3f899fa 276 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 1 83 1.4E-21 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4R43_04545 2bad9107339e0336a7210f9be3f899fa 276 SUPERFAMILY SSF53223 1 95 1.09E-24 T 14-10-2018 A4R43_04545 2bad9107339e0336a7210f9be3f899fa 276 Gene3D G3DSA:3.40.50.10860 1 257 9.6E-81 T 14-10-2018 A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 9.7E-57 T 14-10-2018 A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 SUPERFAMILY SSF51735 5 242 1.66E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_22700 655863f554dfb9e068ae67a0f1dbbb22 263 Gene3D G3DSA:3.40.50.720 1 250 1.0E-74 T 14-10-2018 A4R43_34045 6a175baf0e4cd1f8b98ce952e8ad2816 465 PIRSF PIRSF017804 1 463 2.5E-115 T 14-10-2018 IPR006707 Type VII secretion system membrane protein EccD A4R43_34045 6a175baf0e4cd1f8b98ce952e8ad2816 465 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 460 2.7E-87 T 14-10-2018 IPR006707 Type VII secretion system membrane protein EccD A4R43_34045 6a175baf0e4cd1f8b98ce952e8ad2816 465 Gene3D G3DSA:3.10.20.90 4 85 3.1E-14 T 14-10-2018 A4R43_34045 6a175baf0e4cd1f8b98ce952e8ad2816 465 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 84 1.3E-23 T 14-10-2018 IPR024962 YukD-like A4R43_38135 55d2c651bd4ca1905bdf849824dffd8c 234 SUPERFAMILY SSF46689 14 93 1.85E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38135 55d2c651bd4ca1905bdf849824dffd8c 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.8E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38135 55d2c651bd4ca1905bdf849824dffd8c 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.8E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38135 55d2c651bd4ca1905bdf849824dffd8c 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 3.3E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38135 55d2c651bd4ca1905bdf849824dffd8c 234 Gene3D G3DSA:1.10.357.10 11 214 4.2E-38 T 14-10-2018 A4R43_38135 55d2c651bd4ca1905bdf849824dffd8c 234 SUPERFAMILY SSF48498 94 205 3.93E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_24000 0a7b139a22fbf5b05d9b77fec36bfedb 320 Pfam PF00487 Fatty acid desaturase 59 274 5.3E-20 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_24000 0a7b139a22fbf5b05d9b77fec36bfedb 320 PRINTS PR00075 Fatty acid desaturase family 1 signature 262 276 5.1E-18 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_24000 0a7b139a22fbf5b05d9b77fec36bfedb 320 PRINTS PR00075 Fatty acid desaturase family 1 signature 82 102 5.1E-18 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_24000 0a7b139a22fbf5b05d9b77fec36bfedb 320 PRINTS PR00075 Fatty acid desaturase family 1 signature 219 240 5.1E-18 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_24000 0a7b139a22fbf5b05d9b77fec36bfedb 320 PRINTS PR00075 Fatty acid desaturase family 1 signature 59 81 5.1E-18 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_31790 3aa03c656e4c3c5fef0f605e271bde7c 251 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 22 119 1.9E-19 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_31790 3aa03c656e4c3c5fef0f605e271bde7c 251 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 228 2.0E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_31790 3aa03c656e4c3c5fef0f605e271bde7c 251 Gene3D G3DSA:1.10.3720.10 8 232 4.2E-50 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_31790 3aa03c656e4c3c5fef0f605e271bde7c 251 SUPERFAMILY SSF161098 20 215 5.63E-39 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_11065 883c29327586de96f96a7342f8bccb5b 393 Pfam PF00144 Beta-lactamase 50 378 7.4E-57 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_11065 883c29327586de96f96a7342f8bccb5b 393 Gene3D G3DSA:3.40.710.10 38 385 4.0E-68 T 14-10-2018 A4R43_11065 883c29327586de96f96a7342f8bccb5b 393 SUPERFAMILY SSF56601 40 379 6.3E-67 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_37750 f418e82b1fa30e41ce273df36f71de29 251 SMART SM00824 Thioesterase 24 245 1.0E-5 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4R43_37750 f418e82b1fa30e41ce273df36f71de29 251 Gene3D G3DSA:3.40.50.1820 2 248 1.2E-72 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_37750 f418e82b1fa30e41ce273df36f71de29 251 Pfam PF00975 Thioesterase domain 22 243 2.0E-56 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_37750 f418e82b1fa30e41ce273df36f71de29 251 SUPERFAMILY SSF53474 5 245 1.92E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06705 e35b733356e991a00fedfd870b40148a 139 SUPERFAMILY SSF103196 3 130 1.92E-33 T 14-10-2018 A4R43_06705 e35b733356e991a00fedfd870b40148a 139 Pfam PF03259 Roadblock/LC7 domain 9 101 1.1E-21 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_06705 e35b733356e991a00fedfd870b40148a 139 SMART SM00960 9 101 8.6E-26 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_06705 e35b733356e991a00fedfd870b40148a 139 Gene3D G3DSA:3.30.450.30 6 132 3.4E-40 T 14-10-2018 A4R43_27755 316da1db143d5ae61cc956063c48ed24 81 SUPERFAMILY SSF47598 4 39 1.94E-6 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4R43_30970 c8bfd4468278573a38368114918a8070 231 Gene3D G3DSA:1.10.357.10 11 230 1.3E-60 T 14-10-2018 A4R43_30970 c8bfd4468278573a38368114918a8070 231 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 88 224 2.4E-15 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_30970 c8bfd4468278573a38368114918a8070 231 SUPERFAMILY SSF48498 90 227 9.9E-25 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_30970 c8bfd4468278573a38368114918a8070 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 2.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_30970 c8bfd4468278573a38368114918a8070 231 SUPERFAMILY SSF46689 20 87 1.15E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_09190 7fd75cbbb58fabc2f99664d701c53b7d 292 SUPERFAMILY SSF51735 7 259 9.85E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09190 7fd75cbbb58fabc2f99664d701c53b7d 292 Pfam PF13460 NAD(P)H-binding 15 151 1.6E-14 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_09190 7fd75cbbb58fabc2f99664d701c53b7d 292 Gene3D G3DSA:3.90.25.10 146 267 1.7E-54 T 14-10-2018 A4R43_09190 7fd75cbbb58fabc2f99664d701c53b7d 292 Gene3D G3DSA:3.40.50.720 10 203 1.7E-54 T 14-10-2018 A4R43_11425 1bd8f3d98f7574ec78201caffc8bfe57 233 Gene3D G3DSA:3.10.520.20 1 81 1.8E-13 T 14-10-2018 A4R43_11425 1bd8f3d98f7574ec78201caffc8bfe57 233 Gene3D G3DSA:3.10.520.20 82 232 1.4E-43 T 14-10-2018 A4R43_11425 1bd8f3d98f7574ec78201caffc8bfe57 233 SUPERFAMILY SSF143631 1 230 1.36E-59 T 14-10-2018 IPR003374 ApbE-like superfamily A4R43_11425 1bd8f3d98f7574ec78201caffc8bfe57 233 Pfam PF02424 ApbE family 1 80 1.7E-12 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 A4R43_11425 1bd8f3d98f7574ec78201caffc8bfe57 233 Pfam PF02424 ApbE family 85 215 1.1E-35 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 A4R43_04520 2840d421f93632595a0a0a0c61cebcd6 132 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 2.5E-23 T 14-10-2018 IPR009293 Uncharacterised protein family UPF0478 A4R43_31460 3fd9fd0cc5c9f26329888190d716876e 215 SUPERFAMILY SSF75217 48 209 3.01E-40 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases A4R43_31460 3fd9fd0cc5c9f26329888190d716876e 215 Pfam PF00588 SpoU rRNA Methylase family 66 202 9.3E-26 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4R43_31460 3fd9fd0cc5c9f26329888190d716876e 215 Gene3D G3DSA:3.40.1280.10 46 215 5.4E-35 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4R43_23820 c586e82eca022907cf203f2e9692d67a 399 Pfam PF07730 Histidine kinase 189 252 6.8E-16 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_23820 c586e82eca022907cf203f2e9692d67a 399 SUPERFAMILY SSF55874 296 397 8.66E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_23820 c586e82eca022907cf203f2e9692d67a 399 Gene3D G3DSA:3.30.565.10 270 396 2.4E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_40105 190a891f87903626bf582be71a42d76c 115 SUPERFAMILY SSF54593 17 114 9.63E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_40105 190a891f87903626bf582be71a42d76c 115 Gene3D G3DSA:3.10.180.10 16 115 6.7E-30 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_40105 190a891f87903626bf582be71a42d76c 115 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 66 106 5.1E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_22170 5a1a3b1c593eb053a1d5097225870388 453 Pfam PF00561 alpha/beta hydrolase fold 38 427 4.2E-54 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22170 5a1a3b1c593eb053a1d5097225870388 453 SUPERFAMILY SSF53474 36 439 1.86E-25 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_18260 8f87f0fadded36473bea1dbb81553545 405 Gene3D G3DSA:1.20.1250.20 213 400 1.7E-17 T 14-10-2018 A4R43_18260 8f87f0fadded36473bea1dbb81553545 405 SUPERFAMILY SSF103473 25 399 6.02E-39 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18260 8f87f0fadded36473bea1dbb81553545 405 Pfam PF07690 Major Facilitator Superfamily 32 365 2.0E-20 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_18260 8f87f0fadded36473bea1dbb81553545 405 Gene3D G3DSA:1.20.1250.20 13 208 1.1E-11 T 14-10-2018 A4R43_18555 75a879becb8a4bab41e34033f3720c4e 81 SUPERFAMILY SSF89957 5 76 1.31E-5 T 14-10-2018 IPR029756 MTH1187/YkoF-like A4R43_20500 e60c999ba16f42e00598571e54010c56 345 SUPERFAMILY SSF51182 6 339 6.12E-51 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_20500 e60c999ba16f42e00598571e54010c56 345 Gene3D G3DSA:2.60.120.10 269 337 4.0E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_20500 e60c999ba16f42e00598571e54010c56 345 Gene3D G3DSA:2.60.120.10 5 238 2.8E-40 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_29510 bbe2a20c179441c0814a9ad9ddba5812 193 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 8 187 29.52 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_29510 bbe2a20c179441c0814a9ad9ddba5812 193 Gene3D G3DSA:1.10.286.10 4 49 4.8E-13 T 14-10-2018 A4R43_29510 bbe2a20c179441c0814a9ad9ddba5812 193 Gene3D G3DSA:3.30.1130.10 56 189 7.9E-44 T 14-10-2018 A4R43_29510 bbe2a20c179441c0814a9ad9ddba5812 193 SUPERFAMILY SSF55620 7 186 4.82E-52 T 14-10-2018 A4R43_29510 bbe2a20c179441c0814a9ad9ddba5812 193 Pfam PF01227 GTP cyclohydrolase I 16 185 3.8E-51 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4R43_11710 337b0d5ea88de0231a1900f3223fb68a 272 Gene3D G3DSA:2.60.200.20 25 101 2.1E-5 T 14-10-2018 A4R43_11710 337b0d5ea88de0231a1900f3223fb68a 272 SUPERFAMILY SSF49879 19 99 4.97E-8 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 A4R43_01545 f05e00c74811803db3a6989bc7bb2a0c 342 Pfam PF00487 Fatty acid desaturase 58 314 8.7E-44 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_01545 f05e00c74811803db3a6989bc7bb2a0c 342 PIRSF PIRSF015921 2 340 6.5E-76 T 14-10-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 A4R43_35310 d189b8820433cb8957debed46fe3aa27 569 SUPERFAMILY SSF47203 240 394 4.99E-25 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_35310 d189b8820433cb8957debed46fe3aa27 569 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 388 5.5E-18 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_35310 d189b8820433cb8957debed46fe3aa27 569 SUPERFAMILY SSF56645 13 235 2.88E-22 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_35310 d189b8820433cb8957debed46fe3aa27 569 Gene3D G3DSA:2.40.110.10 133 243 6.4E-12 T 14-10-2018 A4R43_35310 d189b8820433cb8957debed46fe3aa27 569 Gene3D G3DSA:1.20.140.10 244 391 1.2E-20 T 14-10-2018 A4R43_08935 87ba8d4d753052db09c3c80c5c01885c 254 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 3 254 2.3E-108 T 14-10-2018 IPR022292 Conserved hypothetical protein CHP03843 A4R43_23850 6882bab89f966f24dedbfdfd3de2e679 230 SMART SM00986 45 220 1.9E-28 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_23850 6882bab89f966f24dedbfdfd3de2e679 230 SUPERFAMILY SSF52141 13 225 3.6E-42 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_23850 6882bab89f966f24dedbfdfd3de2e679 230 Pfam PF03167 Uracil DNA glycosylase superfamily 45 220 1.5E-25 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_23850 6882bab89f966f24dedbfdfd3de2e679 230 Gene3D G3DSA:3.40.470.10 2 229 8.1E-63 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_23850 6882bab89f966f24dedbfdfd3de2e679 230 SMART SM00987 45 220 1.9E-28 T 14-10-2018 A4R43_22710 02c5309614d33a339c2f520906c4edcd 677 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 4 177 2.4E-53 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 A4R43_22710 02c5309614d33a339c2f520906c4edcd 677 SUPERFAMILY SSF53067 4 351 9.93E-6 T 14-10-2018 A4R43_22710 02c5309614d33a339c2f520906c4edcd 677 Pfam PF01968 Hydantoinase/oxoprolinase 198 492 1.6E-82 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 A4R43_06485 11bfa7e361fdb2f7a1bbc46226603373 214 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 28 210 5.8E-32 T 14-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal A4R43_06485 11bfa7e361fdb2f7a1bbc46226603373 214 SUPERFAMILY SSF81296 28 213 5.6E-31 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_06485 11bfa7e361fdb2f7a1bbc46226603373 214 Gene3D G3DSA:2.70.50.50 28 213 1.1E-64 T 14-10-2018 A4R43_41690 6bbc55f211e53eb8ff8616e1419b2dfe 389 Pfam PF13535 ATP-grasp domain 131 269 7.6E-8 T 14-10-2018 A4R43_41690 6bbc55f211e53eb8ff8616e1419b2dfe 389 Gene3D G3DSA:3.30.470.20 97 388 2.5E-51 T 14-10-2018 A4R43_41690 6bbc55f211e53eb8ff8616e1419b2dfe 389 SUPERFAMILY SSF56059 88 295 5.3E-26 T 14-10-2018 A4R43_16725 d010a117a4ba09700fdf70b7bcdbed23 354 Pfam PF10056 Uncharacterized conserved protein (DUF2293) 267 352 7.9E-24 T 14-10-2018 IPR018744 Domain of unknown function DUF2293 A4R43_07805 c2fd9bfd1bf1b0827e467845718ebe29 280 Pfam PF13847 Methyltransferase domain 38 141 3.6E-14 T 14-10-2018 IPR025714 Methyltransferase domain A4R43_07805 c2fd9bfd1bf1b0827e467845718ebe29 280 Gene3D G3DSA:3.40.50.150 2 257 2.1E-30 T 14-10-2018 A4R43_07805 c2fd9bfd1bf1b0827e467845718ebe29 280 SUPERFAMILY SSF53335 14 203 2.97E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_31825 ddebc37637cdb0840416c3215920e754 386 Gene3D G3DSA:1.20.1250.20 5 372 1.2E-17 T 14-10-2018 A4R43_31825 ddebc37637cdb0840416c3215920e754 386 SUPERFAMILY SSF103473 3 369 7.98E-23 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18220 5a123722044a9723932a2b5191675bd3 317 Gene3D G3DSA:1.10.510.10 210 309 5.0E-20 T 14-10-2018 A4R43_18220 5a123722044a9723932a2b5191675bd3 317 SUPERFAMILY SSF56112 93 292 3.24E-18 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_18220 5a123722044a9723932a2b5191675bd3 317 SMART SM00090 63 308 6.0E-10 T 14-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A4R43_18220 5a123722044a9723932a2b5191675bd3 317 Gene3D G3DSA:3.30.200.20 87 203 2.3E-5 T 14-10-2018 A4R43_18220 5a123722044a9723932a2b5191675bd3 317 Pfam PF01163 RIO1 family 142 297 1.9E-33 T 14-10-2018 A4R43_02415 07bb507d8309dabed42671fa0255f7f2 297 Pfam PF00892 EamA-like transporter family 156 287 2.0E-6 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_02415 07bb507d8309dabed42671fa0255f7f2 297 SUPERFAMILY SSF103481 192 289 9.94E-11 T 14-10-2018 A4R43_05635 bf05c024244428dbd96ecf495abb91b8 206 Gene3D G3DSA:3.90.870.10 1 206 2.3E-63 T 14-10-2018 A4R43_05635 bf05c024244428dbd96ecf495abb91b8 206 SUPERFAMILY SSF55821 1 204 7.32E-61 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A4R43_05635 bf05c024244428dbd96ecf495abb91b8 206 Pfam PF01300 Telomere recombination 23 198 8.6E-44 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 A4R43_05635 bf05c024244428dbd96ecf495abb91b8 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 1.1E-57 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 A4R43_04570 94447df6f816bd049729b6d49ab8e8d1 268 Gene3D G3DSA:3.40.50.150 1 268 3.5E-96 T 14-10-2018 A4R43_04570 94447df6f816bd049729b6d49ab8e8d1 268 Pfam PF04672 S-adenosyl methyltransferase 7 268 9.3E-84 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_04570 94447df6f816bd049729b6d49ab8e8d1 268 PIRSF PIRSF017393 1 268 4.1E-87 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_04570 94447df6f816bd049729b6d49ab8e8d1 268 SUPERFAMILY SSF53335 12 252 1.67E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_15425 2e98c7e28977774ab79a2854b9f7391f 273 SUPERFAMILY SSF51735 3 268 4.72E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_15425 2e98c7e28977774ab79a2854b9f7391f 273 Pfam PF05368 NmrA-like family 116 206 3.4E-6 T 14-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 A4R43_15425 2e98c7e28977774ab79a2854b9f7391f 273 Gene3D G3DSA:3.40.50.720 4 254 1.0E-59 T 14-10-2018 A4R43_15425 2e98c7e28977774ab79a2854b9f7391f 273 Gene3D G3DSA:3.90.25.10 121 256 1.0E-59 T 14-10-2018 A4R43_29110 9809cb6818bb561fe84843786957435f 489 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 466 474 - T 14-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A4R43_29110 9809cb6818bb561fe84843786957435f 489 Pfam PF00905 Penicillin binding protein transpeptidase domain 159 481 3.8E-65 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4R43_29110 9809cb6818bb561fe84843786957435f 489 SUPERFAMILY SSF56601 140 486 7.51E-74 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_29110 9809cb6818bb561fe84843786957435f 489 Gene3D G3DSA:3.90.1310.10 59 379 3.5E-141 T 14-10-2018 A4R43_29110 9809cb6818bb561fe84843786957435f 489 SUPERFAMILY SSF56519 67 121 1.31E-5 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A4R43_29110 9809cb6818bb561fe84843786957435f 489 Gene3D G3DSA:3.40.710.10 139 480 3.5E-141 T 14-10-2018 A4R43_15670 8036dc03b34a343c626abb11078b9f14 491 SUPERFAMILY SSF53720 7 483 9.16E-90 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_15670 8036dc03b34a343c626abb11078b9f14 491 Gene3D G3DSA:3.40.309.10 237 421 6.7E-193 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_15670 8036dc03b34a343c626abb11078b9f14 491 Pfam PF00171 Aldehyde dehydrogenase family 8 432 1.3E-41 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_15670 8036dc03b34a343c626abb11078b9f14 491 Gene3D G3DSA:3.40.605.10 14 486 6.7E-193 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 Gene3D G3DSA:3.30.950.10 282 403 6.1E-42 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 PIRSF PIRSF036426 4 162 1.4E-30 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 PIRSF PIRSF036426 147 403 8.6E-91 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 Gene3D G3DSA:3.40.50.720 7 133 5.9E-31 T 14-10-2018 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 168 379 1.6E-49 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 SUPERFAMILY SSF53790 166 401 2.88E-71 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 168 401 9.2E-79 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 Gene3D G3DSA:3.40.1010.10 166 281 1.2E-37 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 SUPERFAMILY SSF51735 6 108 1.36E-16 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 12 142 8.6E-20 T 14-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4R43_11295 8d4e2920b36369cbeb57a14dc1890ae9 403 Pfam PF13241 Putative NAD(P)-binding 11 118 3.1E-20 T 14-10-2018 A4R43_06730 db92023ad2c4ed161c467528d1f9cfae 299 Gene3D G3DSA:1.10.510.10 120 250 1.1E-15 T 14-10-2018 A4R43_06730 db92023ad2c4ed161c467528d1f9cfae 299 Pfam PF01636 Phosphotransferase enzyme family 26 268 6.8E-14 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_06730 db92023ad2c4ed161c467528d1f9cfae 299 SUPERFAMILY SSF56112 18 247 1.31E-19 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_06730 db92023ad2c4ed161c467528d1f9cfae 299 Gene3D G3DSA:1.20.58.840 140 274 1.1E-15 T 14-10-2018 A4R43_24630 0d502f97eb603b3a577244425b486c87 225 Pfam PF00005 ABC transporter 23 161 2.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_24630 0d502f97eb603b3a577244425b486c87 225 SUPERFAMILY SSF52540 9 219 1.81E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24630 0d502f97eb603b3a577244425b486c87 225 SMART SM00382 31 209 1.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_24630 0d502f97eb603b3a577244425b486c87 225 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_24630 0d502f97eb603b3a577244425b486c87 225 Gene3D G3DSA:3.40.50.300 9 224 2.9E-64 T 14-10-2018 A4R43_28655 233f7d0bb27e5c9fc91785a4c18334e7 279 Gene3D G3DSA:3.40.1750.20 132 198 8.0E-57 T 14-10-2018 A4R43_28655 233f7d0bb27e5c9fc91785a4c18334e7 279 SUPERFAMILY SSF52096 24 231 1.46E-37 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_28655 233f7d0bb27e5c9fc91785a4c18334e7 279 Gene3D G3DSA:3.90.226.10 26 233 8.0E-57 T 14-10-2018 A4R43_28655 233f7d0bb27e5c9fc91785a4c18334e7 279 Pfam PF01343 Peptidase family S49 92 235 4.4E-35 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A4R43_06320 a4666f35bd5c7b727207e51ef9101e76 154 SMART SM00347 32 135 4.4E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06320 a4666f35bd5c7b727207e51ef9101e76 154 Pfam PF12802 MarR family 37 98 2.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06320 a4666f35bd5c7b727207e51ef9101e76 154 Gene3D G3DSA:1.10.10.10 6 153 1.7E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06320 a4666f35bd5c7b727207e51ef9101e76 154 SUPERFAMILY SSF46785 3 149 9.26E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06320 a4666f35bd5c7b727207e51ef9101e76 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06320 a4666f35bd5c7b727207e51ef9101e76 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06320 a4666f35bd5c7b727207e51ef9101e76 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06320 a4666f35bd5c7b727207e51ef9101e76 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 2.2E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_32275 958f87e6ee536dd89fb955bbd712177f 222 Gene3D G3DSA:1.20.58.220 1 213 1.5E-58 T 14-10-2018 IPR038078 PhoU-like domain superfamily A4R43_32275 958f87e6ee536dd89fb955bbd712177f 222 PIRSF PIRSF003107 1 214 4.7E-52 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A4R43_32275 958f87e6ee536dd89fb955bbd712177f 222 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 2.5E-55 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A4R43_32275 958f87e6ee536dd89fb955bbd712177f 222 Pfam PF01895 PhoU domain 122 203 4.9E-11 T 14-10-2018 IPR026022 PhoU domain A4R43_32275 958f87e6ee536dd89fb955bbd712177f 222 Pfam PF01895 PhoU domain 18 103 5.2E-14 T 14-10-2018 IPR026022 PhoU domain A4R43_32275 958f87e6ee536dd89fb955bbd712177f 222 SUPERFAMILY SSF109755 2 214 8.27E-57 T 14-10-2018 A4R43_14190 5130fcb1100221acd3aed1286f879954 167 Pfam PF05154 TM2 domain 99 150 1.8E-9 T 14-10-2018 IPR007829 TM2 domain A4R43_14190 5130fcb1100221acd3aed1286f879954 167 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 3.5E-19 T 14-10-2018 IPR012551 Protein of unknown function DUF1707 A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 72 406 2.0E-50 T 14-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 387 406 2.2E-9 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 77 96 2.2E-9 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 117 136 2.2E-9 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 98 116 2.2E-9 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 344 359 2.2E-9 T 14-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 SUPERFAMILY SSF53383 8 473 4.29E-109 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 Gene3D G3DSA:3.40.640.10 104 349 1.4E-120 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_16450 18a671af5aefcbc961286fc912c60ac1 475 Gene3D G3DSA:3.90.1150.170 40 462 1.4E-120 T 14-10-2018 A4R43_17450 483a2e53c849866eb61e2330461c45cf 371 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 228 237 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A4R43_17450 483a2e53c849866eb61e2330461c45cf 371 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 15 362 1.2E-99 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4R43_17450 483a2e53c849866eb61e2330461c45cf 371 Gene3D G3DSA:3.90.1150.10 18 358 4.4E-130 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_17450 483a2e53c849866eb61e2330461c45cf 371 Gene3D G3DSA:3.40.640.10 55 278 4.4E-130 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_17450 483a2e53c849866eb61e2330461c45cf 371 SUPERFAMILY SSF53383 32 358 1.65E-71 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_17450 483a2e53c849866eb61e2330461c45cf 371 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 13 365 54.805 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4R43_17450 483a2e53c849866eb61e2330461c45cf 371 Pfam PF00155 Aminotransferase class I and II 33 357 2.1E-55 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_41230 c6f8194150477887a7ad7dc12442b630 415 Pfam PF01566 Natural resistance-associated macrophage protein 40 387 2.8E-114 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_41230 c6f8194150477887a7ad7dc12442b630 415 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 23 381 8.6E-88 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_41230 c6f8194150477887a7ad7dc12442b630 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 153 174 7.6E-26 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_41230 c6f8194150477887a7ad7dc12442b630 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 303 322 7.6E-26 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_41230 c6f8194150477887a7ad7dc12442b630 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 127 146 7.6E-26 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_41230 c6f8194150477887a7ad7dc12442b630 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 202 225 7.6E-26 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_41230 c6f8194150477887a7ad7dc12442b630 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 99 125 7.6E-26 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_41230 c6f8194150477887a7ad7dc12442b630 415 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 12 413 33.948 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4R43_40030 49ecc7df84b7cad263e18d04ef0ab2d6 335 ProSitePatterns PS00894 DeoR-type HTH domain signature. 27 61 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4R43_40030 49ecc7df84b7cad263e18d04ef0ab2d6 335 Pfam PF13280 WYL domain 160 328 9.8E-32 T 14-10-2018 IPR026881 WYL domain A4R43_40030 49ecc7df84b7cad263e18d04ef0ab2d6 335 Gene3D G3DSA:1.10.10.10 24 84 2.9E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40030 49ecc7df84b7cad263e18d04ef0ab2d6 335 PIRSF PIRSF016838 83 334 1.6E-19 T 14-10-2018 IPR028349 Protein PafC A4R43_40030 49ecc7df84b7cad263e18d04ef0ab2d6 335 PIRSF PIRSF016838 20 77 0.0049 T 14-10-2018 IPR028349 Protein PafC A4R43_40030 49ecc7df84b7cad263e18d04ef0ab2d6 335 SUPERFAMILY SSF46785 25 82 7.66E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40030 49ecc7df84b7cad263e18d04ef0ab2d6 335 Pfam PF08279 HTH domain 27 82 4.9E-15 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 A4R43_21390 6fb806019b46704c2b705101073532ac 248 SUPERFAMILY SSF46955 4 105 2.93E-20 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_21390 6fb806019b46704c2b705101073532ac 248 Pfam PF13411 MerR HTH family regulatory protein 4 68 1.7E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_21390 6fb806019b46704c2b705101073532ac 248 SMART SM00422 3 72 1.8E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_02755 c89317b537079b3b74ad2a4055975c44 472 SUPERFAMILY SSF56112 10 263 1.32E-59 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_02755 c89317b537079b3b74ad2a4055975c44 472 Pfam PF00069 Protein kinase domain 12 262 1.9E-34 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_02755 c89317b537079b3b74ad2a4055975c44 472 Gene3D G3DSA:1.10.510.10 92 272 7.5E-45 T 14-10-2018 A4R43_02755 c89317b537079b3b74ad2a4055975c44 472 SMART SM00220 12 271 6.1E-38 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_02755 c89317b537079b3b74ad2a4055975c44 472 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_02755 c89317b537079b3b74ad2a4055975c44 472 Gene3D G3DSA:3.30.200.20 1 90 5.8E-15 T 14-10-2018 A4R43_02755 c89317b537079b3b74ad2a4055975c44 472 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_39995 48945e83b0d71c8212a0735a83a3556d 253 SMART SM00346 9 95 3.6E-22 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_39995 48945e83b0d71c8212a0735a83a3556d 253 Gene3D G3DSA:1.10.10.10 2 73 1.1E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39995 48945e83b0d71c8212a0735a83a3556d 253 Gene3D G3DSA:3.30.450.40 79 253 6.7E-48 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_39995 48945e83b0d71c8212a0735a83a3556d 253 Pfam PF01614 Bacterial transcriptional regulator 125 246 6.9E-18 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_39995 48945e83b0d71c8212a0735a83a3556d 253 SUPERFAMILY SSF55781 71 251 3.01E-42 T 14-10-2018 A4R43_39995 48945e83b0d71c8212a0735a83a3556d 253 SUPERFAMILY SSF46785 10 77 2.0E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39995 48945e83b0d71c8212a0735a83a3556d 253 Pfam PF09339 IclR helix-turn-helix domain 11 57 4.8E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_00970 6b3b970670a8638cba44ebdd724aa733 139 Pfam PF12680 SnoaL-like domain 10 123 3.2E-16 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_00970 6b3b970670a8638cba44ebdd724aa733 139 Gene3D G3DSA:3.10.450.50 1 139 2.2E-34 T 14-10-2018 A4R43_00970 6b3b970670a8638cba44ebdd724aa733 139 SUPERFAMILY SSF54427 1 138 5.57E-30 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 Gene3D G3DSA:3.40.50.10860 8 276 1.8E-104 T 14-10-2018 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.0E-60 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.0E-60 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.0E-60 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 1.0E-60 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.0E-60 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.0E-60 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 SUPERFAMILY SSF53223 2 121 1.82E-35 T 14-10-2018 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 SUPERFAMILY SSF51735 123 280 1.26E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 4.8E-59 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.5E-33 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 35.458 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4R43_34550 9bb22174b1bcd5bd97d7d8b9a33549e4 283 Gene3D G3DSA:3.40.50.720 6 258 1.8E-104 T 14-10-2018 A4R43_23635 97f93d078800fdc9623fa9c9f0f63af5 377 Gene3D G3DSA:3.40.1660.10 13 274 1.1E-26 T 14-10-2018 A4R43_23635 97f93d078800fdc9623fa9c9f0f63af5 377 Pfam PF05139 Erythromycin esterase 41 361 7.5E-41 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 A4R43_23635 97f93d078800fdc9623fa9c9f0f63af5 377 Gene3D G3DSA:1.20.1440.30 118 262 1.1E-26 T 14-10-2018 A4R43_23635 97f93d078800fdc9623fa9c9f0f63af5 377 Gene3D G3DSA:3.30.1870.10 42 117 1.1E-26 T 14-10-2018 A4R43_23635 97f93d078800fdc9623fa9c9f0f63af5 377 SUPERFAMILY SSF159501 12 367 5.23E-58 T 14-10-2018 A4R43_10650 6ed6c1907545910e75d28a7c72b55be3 218 SUPERFAMILY SSF52266 27 216 2.6E-35 T 14-10-2018 A4R43_10650 6ed6c1907545910e75d28a7c72b55be3 218 Gene3D G3DSA:3.40.50.1110 29 216 2.4E-28 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_10650 6ed6c1907545910e75d28a7c72b55be3 218 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 33 204 4.0E-23 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_29840 615fa359e5197cf18f8125c0b04a12d5 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 90 1.2E-13 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_29840 615fa359e5197cf18f8125c0b04a12d5 106 Gene3D G3DSA:3.10.20.30 1 105 3.0E-35 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_29840 615fa359e5197cf18f8125c0b04a12d5 106 SUPERFAMILY SSF54292 3 105 1.13E-30 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_29840 615fa359e5197cf18f8125c0b04a12d5 106 PRINTS PR00355 Adrenodoxin signature 82 90 6.3E-6 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4R43_29840 615fa359e5197cf18f8125c0b04a12d5 106 PRINTS PR00355 Adrenodoxin signature 59 73 6.3E-6 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4R43_29840 615fa359e5197cf18f8125c0b04a12d5 106 PRINTS PR00355 Adrenodoxin signature 40 50 6.3E-6 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4R43_16855 18dcada244c178e759bfb7c9431b3eb4 233 Gene3D G3DSA:3.40.830.10 122 233 2.4E-24 T 14-10-2018 A4R43_16855 18dcada244c178e759bfb7c9431b3eb4 233 SUPERFAMILY SSF53213 128 231 1.7E-8 T 14-10-2018 A4R43_09685 d899595a82c0c50f1cda336003638065 472 ProSitePatterns PS00217 Sugar transport proteins signature 2. 131 156 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_09685 d899595a82c0c50f1cda336003638065 472 ProSitePatterns PS00216 Sugar transport proteins signature 1. 312 329 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_09685 d899595a82c0c50f1cda336003638065 472 SUPERFAMILY SSF103473 12 443 5.49E-61 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_09685 d899595a82c0c50f1cda336003638065 472 Gene3D G3DSA:1.20.1250.20 19 447 4.7E-61 T 14-10-2018 A4R43_09685 d899595a82c0c50f1cda336003638065 472 Pfam PF00083 Sugar (and other) transporter 22 239 9.3E-28 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_30205 7494adbc2c12b8181918542647e51172 161 Gene3D G3DSA:3.10.129.10 7 142 2.6E-34 T 14-10-2018 A4R43_30205 7494adbc2c12b8181918542647e51172 161 SUPERFAMILY SSF54637 9 134 1.5E-33 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_30205 7494adbc2c12b8181918542647e51172 161 Pfam PF03061 Thioesterase superfamily 53 119 3.5E-8 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_09390 627da511d8b8d8c1893143f68d80509c 238 SUPERFAMILY SSF53335 15 230 2.84E-22 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_09390 627da511d8b8d8c1893143f68d80509c 238 Gene3D G3DSA:3.40.50.150 25 176 1.3E-17 T 14-10-2018 A4R43_35215 58beecb87a28f97893669d4de665de4f 273 Pfam PF02237 Biotin protein ligase C terminal domain 222 269 4.0E-9 T 14-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_35215 58beecb87a28f97893669d4de665de4f 273 Gene3D G3DSA:2.30.30.100 223 271 4.6E-13 T 14-10-2018 A4R43_35215 58beecb87a28f97893669d4de665de4f 273 Gene3D G3DSA:3.30.930.10 1 222 4.8E-54 T 14-10-2018 A4R43_35215 58beecb87a28f97893669d4de665de4f 273 SUPERFAMILY SSF50037 225 269 5.49E-7 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal A4R43_35215 58beecb87a28f97893669d4de665de4f 273 Pfam PF03099 Biotin/lipoate A/B protein ligase family 44 152 6.2E-8 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A4R43_35215 58beecb87a28f97893669d4de665de4f 273 SUPERFAMILY SSF55681 20 204 1.37E-37 T 14-10-2018 A4R43_35215 58beecb87a28f97893669d4de665de4f 273 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 20 269 2.7E-37 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4R43_23855 e0b15e98ef273c6cd59151ec9ba84a29 489 SUPERFAMILY SSF53474 25 475 2.3E-73 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_23855 e0b15e98ef273c6cd59151ec9ba84a29 489 Gene3D G3DSA:3.40.50.1820 55 480 1.0E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_23855 e0b15e98ef273c6cd59151ec9ba84a29 489 Pfam PF00450 Serine carboxypeptidase 74 448 9.7E-13 T 14-10-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 A4R43_29080 ca7e7b5c447291a82ec38d06e343e978 709 Gene3D G3DSA:3.30.200.20 4 89 4.9E-14 T 14-10-2018 A4R43_29080 ca7e7b5c447291a82ec38d06e343e978 709 Gene3D G3DSA:1.10.510.10 93 266 2.4E-35 T 14-10-2018 A4R43_29080 ca7e7b5c447291a82ec38d06e343e978 709 SUPERFAMILY SSF56112 8 258 1.23E-55 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_29080 ca7e7b5c447291a82ec38d06e343e978 709 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A4R43_29080 ca7e7b5c447291a82ec38d06e343e978 709 Pfam PF00069 Protein kinase domain 12 247 1.1E-38 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 Gene3D G3DSA:3.20.20.70 1 292 4.5E-111 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 Pfam PF16499 Alpha galactosidase A 1 289 1.7E-70 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 SUPERFAMILY SSF51445 2 290 3.42E-80 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 SUPERFAMILY SSF51011 284 376 1.2E-19 T 14-10-2018 A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 Gene3D G3DSA:2.60.40.1180 293 376 1.2E-23 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 Pfam PF17450 Alpha galactosidase A C-terminal beta sandwich domain 296 355 5.2E-5 T 14-10-2018 IPR035373 Alpha galactosidase A, C-terminal beta-sandwich domain A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 PRINTS PR00740 Glycosyl hydrolase family 27 signature 29 44 5.4E-27 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 PRINTS PR00740 Glycosyl hydrolase family 27 signature 245 266 5.4E-27 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 PRINTS PR00740 Glycosyl hydrolase family 27 signature 140 158 5.4E-27 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_12120 468840ccbdb653bc3d17a853fa687d52 377 PRINTS PR00740 Glycosyl hydrolase family 27 signature 111 128 5.4E-27 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 A4R43_00155 2bbd0b75969543e689941c25a918e489 111 SUPERFAMILY SSF54909 7 110 6.97E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_00155 2bbd0b75969543e689941c25a918e489 111 Gene3D G3DSA:3.30.70.1060 1 111 2.6E-23 T 14-10-2018 A4R43_00155 2bbd0b75969543e689941c25a918e489 111 Pfam PF03795 YCII-related domain 4 110 8.4E-11 T 14-10-2018 IPR005545 YCII-related A4R43_41405 eb4227ba1e9adebaad4e8a5e656876e8 143 Gene3D G3DSA:2.40.330.20 1 139 7.0E-45 T 14-10-2018 IPR038619 MraZ superfamily A4R43_41405 eb4227ba1e9adebaad4e8a5e656876e8 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 128 1.0E-49 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A4R43_41405 eb4227ba1e9adebaad4e8a5e656876e8 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 52.077 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A4R43_41405 eb4227ba1e9adebaad4e8a5e656876e8 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 137 5.1E-19 T 14-10-2018 IPR020603 MraZ domain A4R43_41405 eb4227ba1e9adebaad4e8a5e656876e8 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 2.2E-21 T 14-10-2018 IPR020603 MraZ domain A4R43_41405 eb4227ba1e9adebaad4e8a5e656876e8 143 SUPERFAMILY SSF89447 1 135 1.94E-45 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily A4R43_41405 eb4227ba1e9adebaad4e8a5e656876e8 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 136 3.9E-37 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A4R43_12740 996c7d89b9b9ceeb44ee41e2379140a0 442 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_12740 996c7d89b9b9ceeb44ee41e2379140a0 442 SUPERFAMILY SSF103473 19 427 1.23E-58 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_12740 996c7d89b9b9ceeb44ee41e2379140a0 442 Gene3D G3DSA:1.20.1250.20 19 436 1.7E-60 T 14-10-2018 A4R43_12740 996c7d89b9b9ceeb44ee41e2379140a0 442 Pfam PF00083 Sugar (and other) transporter 22 229 6.4E-23 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_13075 7456c25395dcb608103614c4837334d1 168 SUPERFAMILY SSF55961 20 154 2.66E-19 T 14-10-2018 A4R43_13075 7456c25395dcb608103614c4837334d1 168 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 21 142 1.3E-16 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_13075 7456c25395dcb608103614c4837334d1 168 Gene3D G3DSA:3.30.530.20 22 142 8.5E-17 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_12870 b1d7b528527f47eeaaa91c2904f84c02 176 SUPERFAMILY SSF82607 33 101 8.24E-6 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_12870 b1d7b528527f47eeaaa91c2904f84c02 176 Pfam PF02575 YbaB/EbfC DNA-binding family 32 102 6.7E-7 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_21155 27847f443108f2f9c5bbba26559db14c 116 Gene3D G3DSA:2.30.110.10 7 113 2.2E-6 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_41125 b95be7782b3cf5d891f233b8fe493be1 440 Gene3D G3DSA:1.20.1250.20 3 409 2.4E-49 T 14-10-2018 A4R43_41125 b95be7782b3cf5d891f233b8fe493be1 440 Pfam PF07690 Major Facilitator Superfamily 23 247 1.8E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_41125 b95be7782b3cf5d891f233b8fe493be1 440 SUPERFAMILY SSF103473 8 406 2.09E-55 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_39190 f951e41813cd309ca9e80ff526484348 129 Pfam PF14017 Protein of unknown function (DUF4233) 17 120 6.3E-26 T 14-10-2018 IPR025327 Protein of unknown function DUF4233 A4R43_20625 19bc1105f35d7f447a88144fdd6e71e8 303 Gene3D G3DSA:1.10.1670.40 102 289 1.9E-28 T 14-10-2018 A4R43_20625 19bc1105f35d7f447a88144fdd6e71e8 303 SMART SM00478 139 298 2.5E-4 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4R43_20625 19bc1105f35d7f447a88144fdd6e71e8 303 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 136 284 3.5E-7 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4R43_20625 19bc1105f35d7f447a88144fdd6e71e8 303 SUPERFAMILY SSF48150 121 293 2.27E-26 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4R43_20625 19bc1105f35d7f447a88144fdd6e71e8 303 Gene3D G3DSA:1.10.340.30 127 246 1.9E-28 T 14-10-2018 A4R43_28895 b28c0753d9cb4154d612b11231d57bb2 258 Pfam PF07987 Domain of unkown function (DUF1775) 31 185 2.7E-41 T 14-10-2018 IPR012533 YcnI-like A4R43_28895 b28c0753d9cb4154d612b11231d57bb2 258 Gene3D G3DSA:2.60.40.2230 28 200 3.5E-43 T 14-10-2018 IPR038507 YcnI-like superfamily A4R43_03535 073f4dced7f174483bf204b64be35785 302 SUPERFAMILY SSF53850 89 270 8.01E-40 T 14-10-2018 A4R43_03535 073f4dced7f174483bf204b64be35785 302 Gene3D G3DSA:1.10.10.10 1 84 6.4E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_03535 073f4dced7f174483bf204b64be35785 302 Pfam PF03466 LysR substrate binding domain 88 270 1.2E-41 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_03535 073f4dced7f174483bf204b64be35785 302 SUPERFAMILY SSF46785 2 85 1.59E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_03535 073f4dced7f174483bf204b64be35785 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_03535 073f4dced7f174483bf204b64be35785 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_03535 073f4dced7f174483bf204b64be35785 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_03535 073f4dced7f174483bf204b64be35785 302 Gene3D G3DSA:3.40.190.290 90 285 1.8E-48 T 14-10-2018 A4R43_03535 073f4dced7f174483bf204b64be35785 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.7E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_11250 cbe8d1af7ec3cdde33cf9a6021517a38 232 Pfam PF00376 MerR family regulatory protein 8 38 2.0E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_11250 cbe8d1af7ec3cdde33cf9a6021517a38 232 Gene3D G3DSA:1.10.1660.10 11 224 1.9E-18 T 14-10-2018 A4R43_11250 cbe8d1af7ec3cdde33cf9a6021517a38 232 SUPERFAMILY SSF46955 11 73 3.66E-12 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_11250 cbe8d1af7ec3cdde33cf9a6021517a38 232 SMART SM00422 1 70 4.0E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 896 912 2.6E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 912 924 2.6E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 882 896 2.6E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 Gene3D G3DSA:1.10.10.10 876 936 4.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 SUPERFAMILY SSF52540 24 285 1.1E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 SUPERFAMILY SSF48452 747 850 4.07E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 Pfam PF00196 Bacterial regulatory proteins, luxR family 882 932 1.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 Gene3D G3DSA:1.25.40.10 587 875 4.8E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 Gene3D G3DSA:3.40.50.300 17 189 8.9E-7 T 14-10-2018 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 Pfam PF13191 AAA ATPase domain 25 165 1.4E-13 T 14-10-2018 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 SUPERFAMILY SSF46894 875 932 3.4E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_36100 02499be8e9a4cc056b9c96aae5f17af3 938 SMART SM00421 879 936 6.5E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33620 eee0bbdd7416f2d04d47fe8ee08de8ad 328 Pfam PF02470 MlaD protein 39 112 1.3E-14 T 14-10-2018 IPR003399 Mce/MlaD A4R43_33620 eee0bbdd7416f2d04d47fe8ee08de8ad 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 7.1E-11 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33620 eee0bbdd7416f2d04d47fe8ee08de8ad 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 7.1E-11 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33620 eee0bbdd7416f2d04d47fe8ee08de8ad 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 7.1E-11 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33620 eee0bbdd7416f2d04d47fe8ee08de8ad 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 7.1E-11 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33620 eee0bbdd7416f2d04d47fe8ee08de8ad 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 297 316 7.1E-11 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33620 eee0bbdd7416f2d04d47fe8ee08de8ad 328 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 289 2.1E-57 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_20205 834b880c26a9e6265bf18d5c2bf94c08 417 SUPERFAMILY SSF53756 1 395 2.92E-95 T 14-10-2018 A4R43_20205 834b880c26a9e6265bf18d5c2bf94c08 417 Gene3D G3DSA:3.40.50.2000 5 393 9.8E-101 T 14-10-2018 A4R43_20205 834b880c26a9e6265bf18d5c2bf94c08 417 Gene3D G3DSA:3.40.50.2000 195 377 9.8E-101 T 14-10-2018 A4R43_20205 834b880c26a9e6265bf18d5c2bf94c08 417 Pfam PF13439 Glycosyltransferase Family 4 15 196 5.8E-32 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_20205 834b880c26a9e6265bf18d5c2bf94c08 417 Pfam PF00534 Glycosyl transferases group 1 212 373 6.4E-42 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_39545 b17e26b0a519c6e85dffdca9e9bed5c0 132 SMART SM00422 6 74 7.6E-22 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_39545 b17e26b0a519c6e85dffdca9e9bed5c0 132 Gene3D G3DSA:1.10.1660.10 1 121 2.6E-30 T 14-10-2018 A4R43_39545 b17e26b0a519c6e85dffdca9e9bed5c0 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 9.1E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_39545 b17e26b0a519c6e85dffdca9e9bed5c0 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 9.1E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_39545 b17e26b0a519c6e85dffdca9e9bed5c0 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 9.1E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_39545 b17e26b0a519c6e85dffdca9e9bed5c0 132 SUPERFAMILY SSF46955 6 119 1.65E-28 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_39545 b17e26b0a519c6e85dffdca9e9bed5c0 132 Pfam PF13411 MerR HTH family regulatory protein 6 72 2.6E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_18455 fad02a73cfbebdcce6efc294acc9b781 171 Gene3D G3DSA:2.40.30.60 2 90 4.1E-23 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 A4R43_18455 fad02a73cfbebdcce6efc294acc9b781 171 Gene3D G3DSA:2.30.30.240 94 171 3.8E-9 T 14-10-2018 A4R43_18455 fad02a73cfbebdcce6efc294acc9b781 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 167 22.292 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A4R43_18455 fad02a73cfbebdcce6efc294acc9b781 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 167 3.5E-37 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A4R43_18455 fad02a73cfbebdcce6efc294acc9b781 171 SUPERFAMILY SSF50346 98 167 9.81E-14 T 14-10-2018 IPR011033 PRC-barrel-like superfamily A4R43_18455 fad02a73cfbebdcce6efc294acc9b781 171 Pfam PF01782 RimM N-terminal domain 4 83 5.3E-23 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 A4R43_18455 fad02a73cfbebdcce6efc294acc9b781 171 Pfam PF05239 PRC-barrel domain 95 168 2.7E-9 T 14-10-2018 IPR027275 PRC-barrel domain A4R43_18455 fad02a73cfbebdcce6efc294acc9b781 171 SUPERFAMILY SSF50447 3 90 4.94E-18 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4R43_32810 6f30434d22f4031146e1fe3c7b79fad8 257 Pfam PF01261 Xylose isomerase-like TIM barrel 15 205 7.3E-18 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_32810 6f30434d22f4031146e1fe3c7b79fad8 257 Gene3D G3DSA:3.20.20.150 1 249 5.4E-40 T 14-10-2018 A4R43_32810 6f30434d22f4031146e1fe3c7b79fad8 257 SUPERFAMILY SSF51658 2 238 3.67E-43 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_31725 45dfefdfb1b19c490e703e345e6df5f1 369 Pfam PF06013 Proteins of 100 residues with WXG 17 95 3.5E-10 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_31725 45dfefdfb1b19c490e703e345e6df5f1 369 SUPERFAMILY SSF53955 251 357 2.67E-15 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_31725 45dfefdfb1b19c490e703e345e6df5f1 369 Gene3D G3DSA:1.10.530.10 251 359 5.5E-9 T 14-10-2018 A4R43_31725 45dfefdfb1b19c490e703e345e6df5f1 369 Pfam PF01464 Transglycosylase SLT domain 279 354 3.8E-12 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 A4R43_31725 45dfefdfb1b19c490e703e345e6df5f1 369 Gene3D G3DSA:1.10.287.1060 17 110 7.6E-11 T 14-10-2018 A4R43_31725 45dfefdfb1b19c490e703e345e6df5f1 369 SUPERFAMILY SSF140453 17 110 3.14E-12 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_11540 0ae55042af3b7b464fd2658123c6ff89 133 Gene3D G3DSA:2.30.31.20 2 131 9.3E-37 T 14-10-2018 IPR038658 Sporulation-specific cell division protein SsgB superfamily A4R43_11540 0ae55042af3b7b464fd2658123c6ff89 133 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 20 117 2.6E-27 T 14-10-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4R43_27275 e8fcf3e4faccc700d2350fff9706392d 609 Pfam PF00326 Prolyl oligopeptidase family 400 607 7.2E-44 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_27275 e8fcf3e4faccc700d2350fff9706392d 609 Gene3D G3DSA:2.120.10.30 209 356 2.4E-5 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_27275 e8fcf3e4faccc700d2350fff9706392d 609 Gene3D G3DSA:2.120.10.30 36 208 1.8E-6 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_27275 e8fcf3e4faccc700d2350fff9706392d 609 Gene3D G3DSA:3.40.50.1820 360 608 1.7E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27275 e8fcf3e4faccc700d2350fff9706392d 609 SUPERFAMILY SSF53474 367 602 7.22E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27275 e8fcf3e4faccc700d2350fff9706392d 609 SUPERFAMILY SSF69304 44 347 1.83E-18 T 14-10-2018 A4R43_40785 f652ceb5a37543c63e51b7f4d1b045f3 381 Gene3D G3DSA:3.40.640.10 1 246 2.4E-69 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_40785 f652ceb5a37543c63e51b7f4d1b045f3 381 SUPERFAMILY SSF53383 3 370 2.34E-89 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_40785 f652ceb5a37543c63e51b7f4d1b045f3 381 PIRSF PIRSF000390 1 374 5.5E-90 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_40785 f652ceb5a37543c63e51b7f4d1b045f3 381 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 29 367 6.9E-97 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_40785 f652ceb5a37543c63e51b7f4d1b045f3 381 Gene3D G3DSA:3.90.1150.10 249 373 1.3E-32 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_26635 5779f7f7c53b20b99a606d00f29f04ba 289 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 120 132 5.0E-10 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4R43_26635 5779f7f7c53b20b99a606d00f29f04ba 289 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 166 185 5.0E-10 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4R43_26635 5779f7f7c53b20b99a606d00f29f04ba 289 Pfam PF10502 Signal peptidase, peptidase S26 112 188 6.7E-5 T 14-10-2018 IPR019533 Peptidase S26 A4R43_26635 5779f7f7c53b20b99a606d00f29f04ba 289 Gene3D G3DSA:2.10.109.10 80 211 8.0E-21 T 14-10-2018 A4R43_26635 5779f7f7c53b20b99a606d00f29f04ba 289 SUPERFAMILY SSF51306 89 207 7.5E-22 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4R43_26635 5779f7f7c53b20b99a606d00f29f04ba 289 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 83 187 9.0E-17 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4R43_20835 feecfbe8481e17a53028a3757987a2eb 282 PIRSF PIRSF017393 1 282 1.7E-82 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_20835 feecfbe8481e17a53028a3757987a2eb 282 Gene3D G3DSA:3.40.50.150 1 281 8.5E-98 T 14-10-2018 A4R43_20835 feecfbe8481e17a53028a3757987a2eb 282 Pfam PF04672 S-adenosyl methyltransferase 11 282 2.9E-78 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_20835 feecfbe8481e17a53028a3757987a2eb 282 SUPERFAMILY SSF53335 12 257 1.05E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_22390 f2e0190043aa189ce8fb5778876bc096 383 Pfam PF00953 Glycosyl transferase family 4 92 258 1.1E-33 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A4R43_07215 c6ca6f91157aca87e59316c972a78bc7 188 Gene3D G3DSA:1.20.1290.10 45 185 4.1E-29 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_07215 c6ca6f91157aca87e59316c972a78bc7 188 Pfam PF02627 Carboxymuconolactone decarboxylase family 53 135 1.6E-9 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_07215 c6ca6f91157aca87e59316c972a78bc7 188 SUPERFAMILY SSF69118 1 185 5.76E-30 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_25650 d93a9f6c7b226df47d84fa7515b2a6b7 504 SUPERFAMILY SSF103473 26 369 1.96E-37 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_25650 d93a9f6c7b226df47d84fa7515b2a6b7 504 Gene3D G3DSA:1.20.1250.20 15 185 3.7E-18 T 14-10-2018 A4R43_25650 d93a9f6c7b226df47d84fa7515b2a6b7 504 Pfam PF07690 Major Facilitator Superfamily 206 415 2.5E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_25650 d93a9f6c7b226df47d84fa7515b2a6b7 504 Gene3D G3DSA:1.20.1250.20 189 375 2.7E-15 T 14-10-2018 A4R43_35650 a1a9ad282df31f8fd53a1b6341905a4d 208 SUPERFAMILY SSF53335 35 205 1.75E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_35650 a1a9ad282df31f8fd53a1b6341905a4d 208 Pfam PF01596 O-methyltransferase 32 204 2.4E-23 T 14-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 A4R43_35650 a1a9ad282df31f8fd53a1b6341905a4d 208 Gene3D G3DSA:3.40.50.150 5 207 1.4E-53 T 14-10-2018 A4R43_06720 a2d916ad40bbffe77e3826c635a7f299 78 SMART SM00316 15 76 1.2E-10 T 14-10-2018 IPR022967 RNA-binding domain, S1 A4R43_06720 a2d916ad40bbffe77e3826c635a7f299 78 SUPERFAMILY SSF50249 3 74 1.87E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_06720 a2d916ad40bbffe77e3826c635a7f299 78 Pfam PF00575 S1 RNA binding domain 16 74 1.1E-7 T 14-10-2018 IPR003029 S1 domain GO:0003676 A4R43_06720 a2d916ad40bbffe77e3826c635a7f299 78 Gene3D G3DSA:2.40.50.140 18 78 1.2E-12 T 14-10-2018 A4R43_02000 d0157fdbf87a14052bdc129fcd81d9e8 121 Pfam PF01022 Bacterial regulatory protein, arsR family 31 76 1.9E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02000 d0157fdbf87a14052bdc129fcd81d9e8 121 Gene3D G3DSA:1.10.10.10 9 113 6.2E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02000 d0157fdbf87a14052bdc129fcd81d9e8 121 SMART SM00418 24 102 1.8E-26 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02000 d0157fdbf87a14052bdc129fcd81d9e8 121 SUPERFAMILY SSF46785 18 97 1.47E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02000 d0157fdbf87a14052bdc129fcd81d9e8 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 26 41 1.2E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02000 d0157fdbf87a14052bdc129fcd81d9e8 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 1.2E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_02000 d0157fdbf87a14052bdc129fcd81d9e8 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.2E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_00995 c55d5baca127b7dae285d68af473398a 418 SUPERFAMILY SSF103473 10 415 2.35E-58 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_00995 c55d5baca127b7dae285d68af473398a 418 Pfam PF07690 Major Facilitator Superfamily 47 310 1.9E-22 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_00995 c55d5baca127b7dae285d68af473398a 418 Gene3D G3DSA:1.20.1250.20 9 417 1.4E-52 T 14-10-2018 A4R43_35885 6e1b46f314f6c5ff0ac0e4a7fc6a5bca 253 SUPERFAMILY SSF56112 23 177 1.43E-8 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_35885 6e1b46f314f6c5ff0ac0e4a7fc6a5bca 253 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 3 245 1.6E-68 T 14-10-2018 IPR013402 Conserved hypothetical protein CHP02569 A4R43_35710 6a71d12adfcbe5d60af4de83d2f89f14 440 Gene3D G3DSA:3.40.190.10 153 424 2.4E-63 T 14-10-2018 A4R43_35710 6a71d12adfcbe5d60af4de83d2f89f14 440 Gene3D G3DSA:3.40.190.10 69 389 2.4E-63 T 14-10-2018 A4R43_35710 6a71d12adfcbe5d60af4de83d2f89f14 440 SUPERFAMILY SSF53850 46 411 2.72E-62 T 14-10-2018 A4R43_35710 6a71d12adfcbe5d60af4de83d2f89f14 440 Pfam PF01547 Bacterial extracellular solute-binding protein 51 337 5.3E-26 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_40375 4a4bff7bcef60c89dc5ed4d0f1e8792d 115 Pfam PF05331 Protein of unknown function (DUF742) 4 114 7.7E-35 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_39350 7a52aafe89d286131d6638cb9a9f1087 142 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 16 122 9.7E-20 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_39350 7a52aafe89d286131d6638cb9a9f1087 142 SUPERFAMILY SSF55961 3 133 1.2E-35 T 14-10-2018 A4R43_39350 7a52aafe89d286131d6638cb9a9f1087 142 Gene3D G3DSA:3.30.530.20 2 137 2.2E-35 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_24105 d2aaf7c6e1ab1e0e8089ac98cca81726 255 Pfam PF01061 ABC-2 type transporter 4 218 2.6E-29 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_24105 d2aaf7c6e1ab1e0e8089ac98cca81726 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 23 44 2.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_24105 d2aaf7c6e1ab1e0e8089ac98cca81726 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 103 128 2.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_24105 d2aaf7c6e1ab1e0e8089ac98cca81726 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 2.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_24105 d2aaf7c6e1ab1e0e8089ac98cca81726 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 2.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_24105 d2aaf7c6e1ab1e0e8089ac98cca81726 255 PIRSF PIRSF006648 1 255 5.6E-45 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_05670 a6142ff9d7f75d94ee083142a326cc4c 299 Gene3D G3DSA:3.40.50.300 2 224 2.2E-59 T 14-10-2018 A4R43_05670 a6142ff9d7f75d94ee083142a326cc4c 299 Pfam PF00005 ABC transporter 21 155 1.4E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_05670 a6142ff9d7f75d94ee083142a326cc4c 299 SUPERFAMILY SSF52540 5 215 7.26E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_05670 a6142ff9d7f75d94ee083142a326cc4c 299 SMART SM00382 29 203 1.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_05670 a6142ff9d7f75d94ee083142a326cc4c 299 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_16580 03207b6e4a40eefa1d2922515e63d595 360 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_16580 03207b6e4a40eefa1d2922515e63d595 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 352 23.302 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_16580 03207b6e4a40eefa1d2922515e63d595 360 Pfam PF00953 Glycosyl transferase family 4 88 277 2.6E-37 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A4R43_16580 03207b6e4a40eefa1d2922515e63d595 360 ProSitePatterns PS01348 MraY family signature 2. 181 192 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_16580 03207b6e4a40eefa1d2922515e63d595 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 7.0E-6 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_16580 03207b6e4a40eefa1d2922515e63d595 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 348 2.7E-89 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_21860 e0641b70d27937b67fe2f0278d6ae45e 386 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 377 40.236 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21860 e0641b70d27937b67fe2f0278d6ae45e 386 Gene3D G3DSA:3.20.20.140 56 337 6.0E-118 T 14-10-2018 A4R43_21860 e0641b70d27937b67fe2f0278d6ae45e 386 SUPERFAMILY SSF51556 55 336 6.53E-67 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_21860 e0641b70d27937b67fe2f0278d6ae45e 386 Pfam PF01979 Amidohydrolase family 53 354 5.6E-14 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_21860 e0641b70d27937b67fe2f0278d6ae45e 386 TIGRFAM TIGR01224 hutI: imidazolonepropionase 22 374 7.8E-99 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4R43_21860 e0641b70d27937b67fe2f0278d6ae45e 386 SUPERFAMILY SSF51338 317 377 7.56E-13 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_21860 e0641b70d27937b67fe2f0278d6ae45e 386 SUPERFAMILY SSF51338 4 360 9.32E-10 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_21860 e0641b70d27937b67fe2f0278d6ae45e 386 Gene3D G3DSA:2.30.40.10 19 374 6.0E-118 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_32670 28baeccf72f48cbf70e4ac82c707b485 211 Pfam PF13671 AAA domain 41 156 1.6E-7 T 14-10-2018 A4R43_32670 28baeccf72f48cbf70e4ac82c707b485 211 SUPERFAMILY SSF52540 40 209 4.37E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_32670 28baeccf72f48cbf70e4ac82c707b485 211 Gene3D G3DSA:3.40.50.300 37 209 6.4E-27 T 14-10-2018 A4R43_40180 908dcb5a49e5d05038736e44035dc11f 501 SUPERFAMILY SSF63829 302 498 4.41E-25 T 14-10-2018 A4R43_40180 908dcb5a49e5d05038736e44035dc11f 501 SUPERFAMILY SSF63829 200 328 2.16E-8 T 14-10-2018 A4R43_40180 908dcb5a49e5d05038736e44035dc11f 501 Pfam PF13360 PQQ-like domain 299 449 9.5E-5 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4R43_40180 908dcb5a49e5d05038736e44035dc11f 501 Gene3D G3DSA:2.120.10.30 3 147 2.1E-14 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_40180 908dcb5a49e5d05038736e44035dc11f 501 SUPERFAMILY SSF63829 12 205 2.42E-25 T 14-10-2018 A4R43_40180 908dcb5a49e5d05038736e44035dc11f 501 Gene3D G3DSA:2.120.10.30 298 501 2.7E-18 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_40180 908dcb5a49e5d05038736e44035dc11f 501 Gene3D G3DSA:2.120.10.30 151 281 2.2E-6 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_35140 a587d28103d58811193261b4dabdda4e 131 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 91 6.8E-19 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_35140 a587d28103d58811193261b4dabdda4e 131 Gene3D G3DSA:2.30.110.10 3 130 3.2E-36 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_35140 a587d28103d58811193261b4dabdda4e 131 SUPERFAMILY SSF50475 5 128 2.68E-30 T 14-10-2018 A4R43_35140 a587d28103d58811193261b4dabdda4e 131 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 128 8.3E-39 T 14-10-2018 IPR019920 F420-binding domain, putative A4R43_01635 52673b92308899821782e882b2881cba 496 Gene3D G3DSA:3.30.300.30 384 491 2.5E-22 T 14-10-2018 A4R43_01635 52673b92308899821782e882b2881cba 496 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 475 1.5E-14 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_01635 52673b92308899821782e882b2881cba 496 Pfam PF00501 AMP-binding enzyme 12 390 1.5E-56 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_01635 52673b92308899821782e882b2881cba 496 Gene3D G3DSA:3.40.50.12780 3 383 1.6E-69 T 14-10-2018 A4R43_01635 52673b92308899821782e882b2881cba 496 SUPERFAMILY SSF56801 5 487 3.66E-100 T 14-10-2018 A4R43_11590 056a5c99093672d4c27140d67f10eb0e 415 SUPERFAMILY SSF52266 213 408 5.65E-41 T 14-10-2018 A4R43_11590 056a5c99093672d4c27140d67f10eb0e 415 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 215 403 6.4E-21 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_11590 056a5c99093672d4c27140d67f10eb0e 415 Gene3D G3DSA:3.40.50.1110 202 409 1.5E-29 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 Pfam PF13191 AAA ATPase domain 11 141 1.3E-9 T 14-10-2018 A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 SUPERFAMILY SSF46894 835 899 9.86E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 873 885 4.8E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 843 857 4.8E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 857 873 4.8E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 SMART SM00421 840 897 6.5E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 Gene3D G3DSA:1.10.10.10 764 902 2.8E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 Gene3D G3DSA:1.25.40.10 585 740 7.2E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_05610 0a54f2cdc688e39658e68ea1bccd13cc 903 Pfam PF00196 Bacterial regulatory proteins, luxR family 842 893 3.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_19545 8a52508d1cbe404a6cf79f5c27d71231 221 Gene3D G3DSA:2.30.110.10 4 217 5.2E-66 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_19545 8a52508d1cbe404a6cf79f5c27d71231 221 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 22 163 9.1E-41 T 14-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4R43_19545 8a52508d1cbe404a6cf79f5c27d71231 221 SUPERFAMILY SSF50475 4 186 3.27E-53 T 14-10-2018 A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 Gene3D G3DSA:3.40.50.720 5 227 2.2E-60 T 14-10-2018 A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 176 0.0038 T 14-10-2018 A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 Pfam PF00106 short chain dehydrogenase 7 186 7.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 1.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 1.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_30885 5ad42136263310c5b81a055a6f8b94df 227 SUPERFAMILY SSF51735 7 215 1.0E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13815 6cac8cfa76dac612a1385432d9e86f34 214 SUPERFAMILY SSF57997 5 151 2.75E-11 T 14-10-2018 A4R43_13815 6cac8cfa76dac612a1385432d9e86f34 214 Gene3D G3DSA:3.90.20.10 59 204 4.7E-8 T 14-10-2018 A4R43_08540 334b76bff7b02766e0e217fc8714ae92 270 Pfam PF13460 NAD(P)H-binding 6 171 1.6E-15 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_08540 334b76bff7b02766e0e217fc8714ae92 270 Gene3D G3DSA:3.90.25.10 123 253 8.1E-61 T 14-10-2018 A4R43_08540 334b76bff7b02766e0e217fc8714ae92 270 SUPERFAMILY SSF51735 2 264 3.22E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_08540 334b76bff7b02766e0e217fc8714ae92 270 Gene3D G3DSA:3.40.50.720 3 251 8.1E-61 T 14-10-2018 A4R43_36245 bace0b6d020d88bbef10a3457b4c49fa 192 Gene3D G3DSA:1.20.120.450 2 167 7.2E-34 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_36245 bace0b6d020d88bbef10a3457b4c49fa 192 SUPERFAMILY SSF109854 7 165 6.87E-37 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_36245 bace0b6d020d88bbef10a3457b4c49fa 192 Pfam PF04978 Protein of unknown function (DUF664) 16 166 5.8E-44 T 14-10-2018 IPR007061 Protein of unknown function DUF664 A4R43_23770 5aff4d02d351686d8fa75f43ce6c3eb3 361 Gene3D G3DSA:3.20.20.70 5 355 7.6E-112 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_23770 5aff4d02d351686d8fa75f43ce6c3eb3 361 SUPERFAMILY SSF51395 3 351 8.55E-101 T 14-10-2018 A4R43_23770 5aff4d02d351686d8fa75f43ce6c3eb3 361 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 327 3.8E-64 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 Pfam PF00196 Bacterial regulatory proteins, luxR family 2 57 7.6E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 SMART SM00421 2 57 1.7E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 17 33 5.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 33 45 5.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 3 17 5.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 Gene3D G3DSA:3.40.50.300 65 208 4.9E-16 T 14-10-2018 A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 Gene3D G3DSA:1.10.10.10 2 60 1.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 SUPERFAMILY SSF52540 68 318 1.28E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21360 6b7b2620f49a5a75f947960e68af3668 862 SUPERFAMILY SSF46894 2 59 1.02E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 375 384 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 167 183 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 384 395 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 184 199 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 308 319 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 121 132 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 325 352 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 353 368 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00359 B-class P450 signature 227 249 1.6E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 Pfam PF00067 Cytochrome P450 213 405 1.6E-27 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 377 386 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 Gene3D G3DSA:1.10.630.10 16 433 1.1E-110 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00385 P450 superfamily signature 308 319 5.7E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00385 P450 superfamily signature 384 395 5.7E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00385 P450 superfamily signature 375 384 5.7E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 PRINTS PR00385 P450 superfamily signature 273 290 5.7E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15235 f733268d092315425679c70a7e244cb7 434 SUPERFAMILY SSF48264 57 415 2.36E-87 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_31730 6fe368fe0407d7872eab8d2f4bcb0174 203 Pfam PF03734 L,D-transpeptidase catalytic domain 99 201 2.9E-13 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4R43_31730 6fe368fe0407d7872eab8d2f4bcb0174 203 Gene3D G3DSA:2.40.440.10 96 203 4.4E-20 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_31730 6fe368fe0407d7872eab8d2f4bcb0174 203 SUPERFAMILY SSF141523 98 201 1.83E-20 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_02395 c159167e097361bc077973b4dccb35a5 455 Pfam PF00083 Sugar (and other) transporter 69 450 6.8E-28 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_02395 c159167e097361bc077973b4dccb35a5 455 SUPERFAMILY SSF103473 21 450 1.15E-56 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_02395 c159167e097361bc077973b4dccb35a5 455 Gene3D G3DSA:1.20.1250.20 20 454 1.2E-61 T 14-10-2018 A4R43_31805 1713917c296206c25563da4c18b827f4 314 Pfam PF01925 Sulfite exporter TauE/SafE 9 245 4.3E-37 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A4R43_28880 0d71a69301c2c824c2fcf3d342b1a387 215 SUPERFAMILY SSF161098 12 198 5.1E-27 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_28880 0d71a69301c2c824c2fcf3d342b1a387 215 Gene3D G3DSA:1.10.3720.10 14 208 5.7E-22 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_28880 0d71a69301c2c824c2fcf3d342b1a387 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 206 8.1E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_27510 920658167672a2b11ec7d0cdb4c41a35 291 Pfam PF13560 Helix-turn-helix domain 11 72 5.1E-15 T 14-10-2018 A4R43_27510 920658167672a2b11ec7d0cdb4c41a35 291 Gene3D G3DSA:1.10.260.40 4 72 3.2E-11 T 14-10-2018 A4R43_27510 920658167672a2b11ec7d0cdb4c41a35 291 SUPERFAMILY SSF47413 8 65 3.66E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_27510 920658167672a2b11ec7d0cdb4c41a35 291 SMART SM00530 15 70 1.1E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_18060 428d08b97f95011d3e03f9a79ba0ebaa 87 Gene3D G3DSA:1.10.1220.10 2 50 6.8E-7 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A4R43_18060 428d08b97f95011d3e03f9a79ba0ebaa 87 SUPERFAMILY SSF47598 5 58 6.67E-10 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4R43_34460 1732409c8d1b8416a4bc6f511c56ea0d 99 SUPERFAMILY SSF52242 20 59 1.44E-7 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4R43_34460 1732409c8d1b8416a4bc6f511c56ea0d 99 Gene3D G3DSA:3.40.50.280 3 63 1.8E-8 T 14-10-2018 A4R43_31135 d6227b647e7843f75a8ccb61dba08de7 575 Gene3D G3DSA:3.30.950.30 5 146 2.1E-30 T 14-10-2018 IPR038461 Schlafen, AAA domain superfamily A4R43_31135 d6227b647e7843f75a8ccb61dba08de7 575 Gene3D G3DSA:1.10.10.10 494 571 9.1E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31135 d6227b647e7843f75a8ccb61dba08de7 575 Gene3D G3DSA:3.30.565.60 252 412 2.9E-34 T 14-10-2018 IPR038475 RecG, C-terminal domain superfamily A4R43_31135 d6227b647e7843f75a8ccb61dba08de7 575 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 315 409 1.5E-24 T 14-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain A4R43_31135 d6227b647e7843f75a8ccb61dba08de7 575 SUPERFAMILY SSF46785 507 568 1.33E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31135 d6227b647e7843f75a8ccb61dba08de7 575 Pfam PF04326 Putative DNA-binding domain 21 139 6.5E-12 T 14-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 A4R43_31135 d6227b647e7843f75a8ccb61dba08de7 575 Pfam PF01022 Bacterial regulatory protein, arsR family 506 549 3.9E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_07095 b3aadfbcf78bbccb18edc6dea563ccdb 333 Pfam PF05544 Proline racemase 10 332 2.4E-128 T 14-10-2018 IPR008794 Proline racemase family A4R43_07095 b3aadfbcf78bbccb18edc6dea563ccdb 333 Gene3D G3DSA:3.10.310.10 7 333 2.6E-127 T 14-10-2018 A4R43_07095 b3aadfbcf78bbccb18edc6dea563ccdb 333 PIRSF PIRSF029792 1 333 1.4E-128 T 14-10-2018 IPR008794 Proline racemase family A4R43_07095 b3aadfbcf78bbccb18edc6dea563ccdb 333 SUPERFAMILY SSF54506 1 331 4.49E-117 T 14-10-2018 A4R43_07095 b3aadfbcf78bbccb18edc6dea563ccdb 333 Gene3D G3DSA:3.10.310.10 146 310 2.6E-127 T 14-10-2018 A4R43_22080 a9e97180971613debf0f5af6b2c97f4b 124 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 93 103 - T 14-10-2018 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 A4R43_22080 a9e97180971613debf0f5af6b2c97f4b 124 Pfam PF02467 Transcription factor WhiB 34 83 1.3E-14 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain A4R43_22080 a9e97180971613debf0f5af6b2c97f4b 124 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 97 15.754 T 14-10-2018 IPR003482 Transcription factor WhiB A4R43_36205 fb2142317a6c91963d2906bdf9971b48 261 SUPERFAMILY SSF53807 17 253 1.06E-27 T 14-10-2018 A4R43_36205 fb2142317a6c91963d2906bdf9971b48 261 Gene3D G3DSA:3.40.50.1980 137 255 2.4E-7 T 14-10-2018 A4R43_36205 fb2142317a6c91963d2906bdf9971b48 261 Gene3D G3DSA:3.40.50.1980 16 123 7.2E-21 T 14-10-2018 A4R43_31600 cce06699e97d4f747e6746c83226f0ce 93 Pfam PF03795 YCII-related domain 11 82 6.3E-13 T 14-10-2018 IPR005545 YCII-related A4R43_31600 cce06699e97d4f747e6746c83226f0ce 93 SUPERFAMILY SSF54909 1 84 1.61E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_31600 cce06699e97d4f747e6746c83226f0ce 93 Gene3D G3DSA:3.30.70.1060 3 84 1.7E-11 T 14-10-2018 A4R43_15915 dd3ff235f549ac966be0af4830b6aaf4 388 Gene3D G3DSA:3.40.47.10 5 382 6.3E-79 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15915 dd3ff235f549ac966be0af4830b6aaf4 388 SUPERFAMILY SSF53901 11 223 4.8E-21 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15915 dd3ff235f549ac966be0af4830b6aaf4 388 PIRSF PIRSF000429 5 378 1.4E-16 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_15915 dd3ff235f549ac966be0af4830b6aaf4 388 SUPERFAMILY SSF53901 247 371 4.97E-17 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 SUPERFAMILY SSF50249 2 66 1.71E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 PIRSF PIRSF002599 1 68 3.1E-22 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 14-10-2018 IPR019844 Cold-shock conserved site A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 SMART SM00357 3 67 5.4E-31 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 4.6E-29 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 Gene3D G3DSA:2.40.50.140 2 67 6.8E-29 T 14-10-2018 A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 PRINTS PR00050 Cold shock protein signature 24 33 8.6E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 PRINTS PR00050 Cold shock protein signature 4 19 8.6E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_26080 bbc5b84963cc9b5ffe32f8574c341229 68 PRINTS PR00050 Cold shock protein signature 39 57 8.6E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4R43_37125 93fd8beaa51bed47900e6ee0f40e26a3 452 Gene3D G3DSA:3.40.462.20 192 410 1.4E-66 T 14-10-2018 A4R43_37125 93fd8beaa51bed47900e6ee0f40e26a3 452 Gene3D G3DSA:3.30.43.10 2 77 9.5E-10 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4R43_37125 93fd8beaa51bed47900e6ee0f40e26a3 452 SUPERFAMILY SSF56176 4 192 1.36E-39 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_37125 93fd8beaa51bed47900e6ee0f40e26a3 452 Gene3D G3DSA:3.30.465.10 93 436 1.4E-66 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4R43_37125 93fd8beaa51bed47900e6ee0f40e26a3 452 Pfam PF01565 FAD binding domain 26 161 3.0E-19 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_05645 e0597bde552b61931dd93f0c66369936 309 Gene3D G3DSA:2.120.10.30 23 230 3.7E-13 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_05645 e0597bde552b61931dd93f0c66369936 309 SUPERFAMILY SSF63829 30 289 5.56E-25 T 14-10-2018 A4R43_26150 59db21bb39c8980dcc017777dcb3dd99 94 SUPERFAMILY SSF46785 5 76 6.5E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26150 59db21bb39c8980dcc017777dcb3dd99 94 Gene3D G3DSA:1.10.10.10 1 79 1.4E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_28120 64eef79d732d167d326fd860ccfd0ec1 635 Pfam PF13641 Glycosyltransferase like family 2 176 430 9.9E-31 T 14-10-2018 A4R43_28120 64eef79d732d167d326fd860ccfd0ec1 635 SUPERFAMILY SSF53448 176 444 2.81E-27 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_28120 64eef79d732d167d326fd860ccfd0ec1 635 Gene3D G3DSA:3.90.550.60 25 418 1.7E-114 T 14-10-2018 A4R43_25985 8d2139a6b99151ff7dba9b3057156792 309 SUPERFAMILY SSF53850 60 286 1.22E-46 T 14-10-2018 A4R43_25985 8d2139a6b99151ff7dba9b3057156792 309 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 77 287 8.3E-40 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_25985 8d2139a6b99151ff7dba9b3057156792 309 Gene3D G3DSA:3.40.190.10 160 250 7.1E-58 T 14-10-2018 A4R43_25985 8d2139a6b99151ff7dba9b3057156792 309 SMART SM00062 70 292 5.2E-52 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_25985 8d2139a6b99151ff7dba9b3057156792 309 Gene3D G3DSA:3.40.190.10 64 285 7.1E-58 T 14-10-2018 A4R43_35930 04a988424f252ac17e42fe29d574d3e3 134 SUPERFAMILY SSF159238 3 134 3.14E-29 T 14-10-2018 IPR023159 SO1590-like superfamily A4R43_35930 04a988424f252ac17e42fe29d574d3e3 134 Pfam PF11528 Protein of unknown function (DUF3224) 3 132 9.3E-35 T 14-10-2018 IPR021607 Protein of unknown function DUF3224 A4R43_35930 04a988424f252ac17e42fe29d574d3e3 134 Gene3D G3DSA:2.40.350.10 1 132 1.8E-35 T 14-10-2018 IPR023159 SO1590-like superfamily A4R43_20710 d5da5fdd1d7d0485884a290511a24934 149 SUPERFAMILY SSF102712 3 103 1.7E-10 T 14-10-2018 A4R43_20710 d5da5fdd1d7d0485884a290511a24934 149 Gene3D G3DSA:3.40.140.10 1 129 5.8E-15 T 14-10-2018 A4R43_20710 d5da5fdd1d7d0485884a290511a24934 149 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 116 4.3E-14 T 14-10-2018 IPR028090 JAB domain, prokaryotic A4R43_01295 863e6dcab152a463c8884b2e86a3f701 375 Gene3D G3DSA:3.40.50.150 5 236 6.5E-44 T 14-10-2018 A4R43_01295 863e6dcab152a463c8884b2e86a3f701 375 SUPERFAMILY SSF53335 1 199 3.51E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_01295 863e6dcab152a463c8884b2e86a3f701 375 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 216 2.2E-28 T 14-10-2018 A4R43_01295 863e6dcab152a463c8884b2e86a3f701 375 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 157 172 - T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A4R43_03980 55d054a2ffee4ba6dc9faa932adae093 176 Pfam PF15561 Immunity protein 15 29 102 3.7E-9 T 14-10-2018 IPR028264 Immunity protein 15 A4R43_20230 fbf0aab6d1a4740c5b3b06d2ec73d106 420 Gene3D G3DSA:3.40.50.1100 23 324 2.3E-105 T 14-10-2018 A4R43_20230 fbf0aab6d1a4740c5b3b06d2ec73d106 420 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 314 7.6E-79 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_20230 fbf0aab6d1a4740c5b3b06d2ec73d106 420 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 327 419 8.8E-25 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4R43_20230 fbf0aab6d1a4740c5b3b06d2ec73d106 420 Gene3D G3DSA:3.40.1020.10 325 420 4.3E-8 T 14-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4R43_20230 fbf0aab6d1a4740c5b3b06d2ec73d106 420 SUPERFAMILY SSF53686 12 363 1.09E-95 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_20230 fbf0aab6d1a4740c5b3b06d2ec73d106 420 Gene3D G3DSA:3.40.50.1100 57 156 2.3E-105 T 14-10-2018 A4R43_20230 fbf0aab6d1a4740c5b3b06d2ec73d106 420 TIGRFAM TIGR02079 THD1: threonine dehydratase 13 420 2.2E-169 T 14-10-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4R43_07355 064ea5b6026b948624e699eaca9b72fa 234 SMART SM00346 18 105 5.9E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_07355 064ea5b6026b948624e699eaca9b72fa 234 SUPERFAMILY SSF46785 19 87 2.45E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07355 064ea5b6026b948624e699eaca9b72fa 234 Gene3D G3DSA:3.30.450.40 89 213 1.2E-12 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_07355 064ea5b6026b948624e699eaca9b72fa 234 Pfam PF09339 IclR helix-turn-helix domain 21 70 1.1E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_07355 064ea5b6026b948624e699eaca9b72fa 234 SUPERFAMILY SSF55781 90 233 2.68E-20 T 14-10-2018 A4R43_07355 064ea5b6026b948624e699eaca9b72fa 234 Gene3D G3DSA:1.10.10.10 18 88 4.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38080 c3143ce6b81a9c99fd1f8a721325a698 243 SUPERFAMILY SSF48498 89 238 3.67E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_38080 c3143ce6b81a9c99fd1f8a721325a698 243 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 79 1.1E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_38080 c3143ce6b81a9c99fd1f8a721325a698 243 SUPERFAMILY SSF46689 28 85 8.21E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_38080 c3143ce6b81a9c99fd1f8a721325a698 243 Gene3D G3DSA:1.10.357.10 12 242 6.9E-33 T 14-10-2018 A4R43_03120 8ef04a9bfcae4dc8c2cf69cba63f7db6 286 SUPERFAMILY SSF52091 164 274 2.75E-19 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_03120 8ef04a9bfcae4dc8c2cf69cba63f7db6 286 Gene3D G3DSA:3.30.750.24 160 278 1.1E-36 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_03120 8ef04a9bfcae4dc8c2cf69cba63f7db6 286 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 15 112 4.5E-13 T 14-10-2018 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain A4R43_03120 8ef04a9bfcae4dc8c2cf69cba63f7db6 286 Pfam PF01740 STAS domain 173 269 3.9E-9 T 14-10-2018 IPR002645 STAS domain A4R43_25595 72f142b44c702edfdb9533bc4d64acf3 368 SUPERFAMILY SSF53474 57 343 1.09E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25595 72f142b44c702edfdb9533bc4d64acf3 368 PIRSF PIRSF029171 2 368 1.9E-78 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_25595 72f142b44c702edfdb9533bc4d64acf3 368 Gene3D G3DSA:1.10.260.130 201 292 3.5E-113 T 14-10-2018 A4R43_25595 72f142b44c702edfdb9533bc4d64acf3 368 Pfam PF03583 Secretory lipase 99 364 1.1E-52 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_25595 72f142b44c702edfdb9533bc4d64acf3 368 Gene3D G3DSA:3.40.50.1820 4 358 3.5E-113 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27345 b818d93867e1160410ae10ff605d6aa4 193 Pfam PF00881 Nitroreductase family 14 60 5.4E-9 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4R43_27345 b818d93867e1160410ae10ff605d6aa4 193 Pfam PF00881 Nitroreductase family 75 155 4.4E-7 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4R43_27345 b818d93867e1160410ae10ff605d6aa4 193 SUPERFAMILY SSF55469 6 191 1.44E-39 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_27345 b818d93867e1160410ae10ff605d6aa4 193 Gene3D G3DSA:3.40.109.10 1 192 4.0E-43 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_16340 df306b87d75090f55c9e2009a41790f4 256 SUPERFAMILY SSF53474 17 246 3.38E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16340 df306b87d75090f55c9e2009a41790f4 256 Pfam PF12146 Serine aminopeptidase, S33 16 213 1.3E-17 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 A4R43_16340 df306b87d75090f55c9e2009a41790f4 256 Gene3D G3DSA:3.40.50.1820 1 246 9.3E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16340 df306b87d75090f55c9e2009a41790f4 256 PIRSF PIRSF017388 1 249 3.7E-60 T 14-10-2018 IPR012354 Esterase/lipase GO:0052689 A4R43_22110 cbc7405a4e1a714e05f508d89eaf93f5 145 Pfam PF13279 Thioesterase-like superfamily 13 121 1.4E-15 T 14-10-2018 A4R43_22110 cbc7405a4e1a714e05f508d89eaf93f5 145 SUPERFAMILY SSF54637 5 129 6.41E-28 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_22110 cbc7405a4e1a714e05f508d89eaf93f5 145 Gene3D G3DSA:3.10.129.10 2 133 1.5E-29 T 14-10-2018 A4R43_38100 0e0f781506a461f0c3927a47e728ba6b 295 Gene3D G3DSA:1.10.3720.10 54 295 3.5E-69 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_38100 0e0f781506a461f0c3927a47e728ba6b 295 SUPERFAMILY SSF161098 58 282 4.19E-60 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_38100 0e0f781506a461f0c3927a47e728ba6b 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 288 3.2E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_16930 760ad81d04cd895236169719e774ff05 637 SUPERFAMILY SSF46977 481 633 7.72E-42 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16930 760ad81d04cd895236169719e774ff05 637 Gene3D G3DSA:3.50.50.60 10 440 3.7E-147 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_16930 760ad81d04cd895236169719e774ff05 637 PIRSF PIRSF000171 1 605 2.3E-36 T 14-10-2018 A4R43_16930 760ad81d04cd895236169719e774ff05 637 SUPERFAMILY SSF56425 243 389 4.58E-33 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16930 760ad81d04cd895236169719e774ff05 637 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 393 415 1.7E-5 T 14-10-2018 A4R43_16930 760ad81d04cd895236169719e774ff05 637 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.7E-5 T 14-10-2018 A4R43_16930 760ad81d04cd895236169719e774ff05 637 Pfam PF00890 FAD binding domain 10 429 3.5E-90 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16930 760ad81d04cd895236169719e774ff05 637 Gene3D G3DSA:1.20.58.100 471 573 4.4E-30 T 14-10-2018 A4R43_16930 760ad81d04cd895236169719e774ff05 637 SUPERFAMILY SSF51905 3 471 1.2E-73 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_16930 760ad81d04cd895236169719e774ff05 637 Gene3D G3DSA:3.90.700.10 253 395 3.7E-147 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_16930 760ad81d04cd895236169719e774ff05 637 Pfam PF02910 Fumarate reductase flavoprotein C-term 487 587 1.7E-24 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_20315 679b7818028fa9f3f1b9f4834162d550 152 SUPERFAMILY SSF46785 12 145 2.21E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20315 679b7818028fa9f3f1b9f4834162d550 152 Gene3D G3DSA:1.10.10.10 11 149 6.6E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20315 679b7818028fa9f3f1b9f4834162d550 152 SMART SM00347 30 130 1.3E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20315 679b7818028fa9f3f1b9f4834162d550 152 Pfam PF01047 MarR family 41 93 5.6E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20315 679b7818028fa9f3f1b9f4834162d550 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 7.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20315 679b7818028fa9f3f1b9f4834162d550 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 7.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20315 679b7818028fa9f3f1b9f4834162d550 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 7.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20315 679b7818028fa9f3f1b9f4834162d550 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 7.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_23340 a031b9f8261c9b1b1f42e75a07f18734 338 SUPERFAMILY SSF161098 96 319 2.78E-14 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23340 a031b9f8261c9b1b1f42e75a07f18734 338 Gene3D G3DSA:1.10.3720.10 93 329 2.6E-17 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23340 a031b9f8261c9b1b1f42e75a07f18734 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 336 1.1E-37 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_19805 02a8770cd7808754db5d24fe54052fa2 339 SUPERFAMILY SSF52518 27 198 2.73E-47 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_19805 02a8770cd7808754db5d24fe54052fa2 339 SMART SM00861 33 197 3.1E-45 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_19805 02a8770cd7808754db5d24fe54052fa2 339 Pfam PF02780 Transketolase, C-terminal domain 209 330 1.3E-24 T 14-10-2018 IPR033248 Transketolase, C-terminal domain A4R43_19805 02a8770cd7808754db5d24fe54052fa2 339 SUPERFAMILY SSF52922 203 338 4.84E-29 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_19805 02a8770cd7808754db5d24fe54052fa2 339 Gene3D G3DSA:3.40.50.970 32 203 4.7E-49 T 14-10-2018 A4R43_19805 02a8770cd7808754db5d24fe54052fa2 339 Gene3D G3DSA:3.40.50.920 209 338 7.6E-31 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4R43_19805 02a8770cd7808754db5d24fe54052fa2 339 Pfam PF02779 Transketolase, pyrimidine binding domain 34 196 6.3E-34 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4R43_32905 39c5f35e094fdf6d82e1e8b72ae83684 98 Gene3D G3DSA:3.30.1310.10 6 97 1.5E-9 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_32905 39c5f35e094fdf6d82e1e8b72ae83684 98 Pfam PF02575 YbaB/EbfC DNA-binding family 17 90 1.1E-11 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_32905 39c5f35e094fdf6d82e1e8b72ae83684 98 SUPERFAMILY SSF82607 17 91 5.49E-10 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_34890 ec611bf07bba286c6e858dae68854f0b 132 Gene3D G3DSA:1.10.1660.10 1 131 3.8E-32 T 14-10-2018 A4R43_34890 ec611bf07bba286c6e858dae68854f0b 132 SMART SM00422 3 72 2.7E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_34890 ec611bf07bba286c6e858dae68854f0b 132 SUPERFAMILY SSF46955 3 116 3.36E-28 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_34890 ec611bf07bba286c6e858dae68854f0b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 7.0E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_34890 ec611bf07bba286c6e858dae68854f0b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 7.0E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_34890 ec611bf07bba286c6e858dae68854f0b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 7.0E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_34890 ec611bf07bba286c6e858dae68854f0b 132 Pfam PF13411 MerR HTH family regulatory protein 3 69 5.7E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00040 ece4a0379f9b9e001c6d11eeed21c15a 137 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 4 94 1.2E-15 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_00040 ece4a0379f9b9e001c6d11eeed21c15a 137 Gene3D G3DSA:2.30.110.10 2 118 9.4E-24 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_00040 ece4a0379f9b9e001c6d11eeed21c15a 137 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 3 119 3.1E-43 T 14-10-2018 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family KEGG: 00253+1.3.98.4|MetaCyc: PWY-7812 A4R43_00040 ece4a0379f9b9e001c6d11eeed21c15a 137 SUPERFAMILY SSF50475 7 120 2.62E-22 T 14-10-2018 A4R43_09750 ed986de0244d3687a567b96d9d35f725 347 Pfam PF01032 FecCD transport family 20 337 8.5E-87 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_09750 ed986de0244d3687a567b96d9d35f725 347 SUPERFAMILY SSF81345 10 337 1.96E-74 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_09750 ed986de0244d3687a567b96d9d35f725 347 Gene3D G3DSA:1.10.3470.10 8 343 1.8E-94 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_12750 a581c1eaad77509e7e45dff93c4bcf5e 417 SUPERFAMILY SSF55031 213 322 1.38E-14 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_12750 a581c1eaad77509e7e45dff93c4bcf5e 417 Gene3D G3DSA:3.30.70.360 211 328 8.2E-117 T 14-10-2018 A4R43_12750 a581c1eaad77509e7e45dff93c4bcf5e 417 Gene3D G3DSA:3.40.630.10 13 404 8.2E-117 T 14-10-2018 A4R43_12750 a581c1eaad77509e7e45dff93c4bcf5e 417 SUPERFAMILY SSF53187 6 409 1.4E-70 T 14-10-2018 A4R43_12750 a581c1eaad77509e7e45dff93c4bcf5e 417 Pfam PF01546 Peptidase family M20/M25/M40 74 407 1.9E-23 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_12750 a581c1eaad77509e7e45dff93c4bcf5e 417 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 10 406 4.5E-78 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A4R43_12750 a581c1eaad77509e7e45dff93c4bcf5e 417 PIRSF PIRSF001235 1 413 3.9E-106 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A4R43_04125 bfa2996a84336133b24d3c7e753ab70a 307 Gene3D G3DSA:3.40.190.10 63 271 2.4E-56 T 14-10-2018 A4R43_04125 bfa2996a84336133b24d3c7e753ab70a 307 SUPERFAMILY SSF53850 18 284 2.41E-47 T 14-10-2018 A4R43_04125 bfa2996a84336133b24d3c7e753ab70a 307 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 71 282 6.1E-42 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_04125 bfa2996a84336133b24d3c7e753ab70a 307 Gene3D G3DSA:3.40.190.10 153 252 2.4E-56 T 14-10-2018 A4R43_04125 bfa2996a84336133b24d3c7e753ab70a 307 SMART SM00062 68 290 1.5E-56 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_30525 c889ec97e02ae0019783e7ef6fbb0a80 308 SUPERFAMILY SSF53850 9 285 4.06E-47 T 14-10-2018 A4R43_30525 c889ec97e02ae0019783e7ef6fbb0a80 308 Gene3D G3DSA:3.40.190.10 159 249 4.6E-57 T 14-10-2018 A4R43_30525 c889ec97e02ae0019783e7ef6fbb0a80 308 Gene3D G3DSA:3.40.190.10 63 283 4.6E-57 T 14-10-2018 A4R43_30525 c889ec97e02ae0019783e7ef6fbb0a80 308 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 78 282 6.8E-39 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_30525 c889ec97e02ae0019783e7ef6fbb0a80 308 SMART SM00062 69 291 2.2E-46 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_13590 4af02a2713622f83216c5314c601deb0 338 SUPERFAMILY SSF46689 231 280 1.49E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13590 4af02a2713622f83216c5314c601deb0 338 SUPERFAMILY SSF46689 282 333 5.82E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13590 4af02a2713622f83216c5314c601deb0 338 SUPERFAMILY SSF52317 20 211 1.28E-50 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_13590 4af02a2713622f83216c5314c601deb0 338 Pfam PF01965 DJ-1/PfpI family 20 190 5.2E-28 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_13590 4af02a2713622f83216c5314c601deb0 338 Pfam PF12833 Helix-turn-helix domain 252 330 1.4E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_13590 4af02a2713622f83216c5314c601deb0 338 Gene3D G3DSA:3.40.50.880 17 219 5.0E-63 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_13590 4af02a2713622f83216c5314c601deb0 338 SMART SM00342 246 329 3.1E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_13590 4af02a2713622f83216c5314c601deb0 338 Gene3D G3DSA:1.10.10.60 226 337 1.3E-25 T 14-10-2018 A4R43_30740 158ba6e121d260f467ffeef7cec443ce 460 Gene3D G3DSA:1.20.1260.20 41 138 1.3E-5 T 14-10-2018 IPR038332 PPE superfamily A4R43_22545 ce0e336523b231e563a60faffe1fc6e6 305 Gene3D G3DSA:1.20.1510.10 20 215 5.0E-39 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4R43_22545 ce0e336523b231e563a60faffe1fc6e6 305 SUPERFAMILY SSF161111 18 216 1.7E-50 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4R43_22545 ce0e336523b231e563a60faffe1fc6e6 305 SUPERFAMILY SSF160240 219 294 4.32E-10 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A4R43_22545 ce0e336523b231e563a60faffe1fc6e6 305 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 295 3.5E-76 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4R43_22545 ce0e336523b231e563a60faffe1fc6e6 305 Pfam PF01545 Cation efflux family 24 214 1.1E-41 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4R43_16660 5dbab9334b60eb9f7746cc64df2f0660 357 SUPERFAMILY SSF56645 1 208 5.1E-32 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_16660 5dbab9334b60eb9f7746cc64df2f0660 357 Gene3D G3DSA:1.10.540.10 1 117 2.3E-24 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_16660 5dbab9334b60eb9f7746cc64df2f0660 357 Gene3D G3DSA:1.20.140.10 221 356 1.6E-37 T 14-10-2018 A4R43_16660 5dbab9334b60eb9f7746cc64df2f0660 357 Gene3D G3DSA:2.40.110.10 118 216 3.0E-18 T 14-10-2018 A4R43_16660 5dbab9334b60eb9f7746cc64df2f0660 357 SUPERFAMILY SSF47203 220 355 1.08E-36 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_16660 5dbab9334b60eb9f7746cc64df2f0660 357 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 347 5.1E-30 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_16660 5dbab9334b60eb9f7746cc64df2f0660 357 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 112 1.5E-11 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_10425 a346dacbf1d3d11ab2c0b7fe57fe7b7b 309 Pfam PF04616 Glycosyl hydrolases family 43 49 257 2.3E-8 T 14-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4R43_10425 a346dacbf1d3d11ab2c0b7fe57fe7b7b 309 Gene3D G3DSA:2.115.10.20 30 307 3.4E-25 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_10425 a346dacbf1d3d11ab2c0b7fe57fe7b7b 309 SUPERFAMILY SSF75005 46 296 2.22E-29 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_08200 7f8481caf25ef4a627502153bbc257f6 219 SUPERFAMILY SSF52540 4 216 1.95E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08200 7f8481caf25ef4a627502153bbc257f6 219 Gene3D G3DSA:3.40.50.300 5 217 4.6E-54 T 14-10-2018 A4R43_08200 7f8481caf25ef4a627502153bbc257f6 219 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_08200 7f8481caf25ef4a627502153bbc257f6 219 SMART SM00382 34 213 1.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08200 7f8481caf25ef4a627502153bbc257f6 219 Pfam PF00005 ABC transporter 25 166 4.3E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_03020 9a5eedf60433d9b8112ddc1442549109 130 Gene3D G3DSA:3.30.750.24 15 129 2.6E-25 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_03020 9a5eedf60433d9b8112ddc1442549109 130 Pfam PF13466 STAS domain 33 112 3.0E-12 T 14-10-2018 IPR002645 STAS domain A4R43_03020 9a5eedf60433d9b8112ddc1442549109 130 SUPERFAMILY SSF52091 20 126 1.75E-18 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_03020 9a5eedf60433d9b8112ddc1442549109 130 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 20 123 4.6E-18 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_01830 26e5b7a7aac862a4cacbbdbde82dcba7 243 SUPERFAMILY SSF53335 7 222 2.2E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_01830 26e5b7a7aac862a4cacbbdbde82dcba7 243 Pfam PF13649 Methyltransferase domain 43 134 5.5E-11 T 14-10-2018 A4R43_01830 26e5b7a7aac862a4cacbbdbde82dcba7 243 Gene3D G3DSA:3.40.50.150 11 220 1.7E-62 T 14-10-2018 A4R43_01830 26e5b7a7aac862a4cacbbdbde82dcba7 243 Gene3D G3DSA:2.20.130.10 147 204 1.7E-62 T 14-10-2018 A4R43_17020 5869d74f85cce6fe287759e478c25d55 305 SUPERFAMILY SSF103481 49 152 9.02E-8 T 14-10-2018 A4R43_17020 5869d74f85cce6fe287759e478c25d55 305 SUPERFAMILY SSF103481 202 302 8.5E-13 T 14-10-2018 A4R43_17020 5869d74f85cce6fe287759e478c25d55 305 Pfam PF00892 EamA-like transporter family 167 297 3.8E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_17020 5869d74f85cce6fe287759e478c25d55 305 Pfam PF00892 EamA-like transporter family 14 149 2.8E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_24045 628917944f614ca23841e3e124c78f18 119 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 1.5E-8 T 14-10-2018 IPR019933 DivIVA domain A4R43_24045 628917944f614ca23841e3e124c78f18 119 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 45 80 7.7E-11 T 14-10-2018 IPR019933 DivIVA domain A4R43_21320 a5c751ca44020ce984e8eb8823e0fa6d 252 SMART SM00882 7 215 2.7E-19 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_21320 a5c751ca44020ce984e8eb8823e0fa6d 252 SUPERFAMILY SSF100950 2 250 1.38E-60 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_21320 a5c751ca44020ce984e8eb8823e0fa6d 252 Pfam PF01144 Coenzyme A transferase 12 214 3.8E-25 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_21320 a5c751ca44020ce984e8eb8823e0fa6d 252 Gene3D G3DSA:3.40.1080.10 2 252 4.7E-80 T 14-10-2018 A4R43_37570 132e164486d409e6a4994d2beb347857 368 SUPERFAMILY SSF53300 202 341 2.78E-17 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_37570 132e164486d409e6a4994d2beb347857 368 Pfam PF05762 VWA domain containing CoxE-like protein 146 359 1.4E-53 T 14-10-2018 IPR008912 Uncharacterised protein family CoxE-like A4R43_37570 132e164486d409e6a4994d2beb347857 368 SMART SM00327 204 363 0.0089 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_37570 132e164486d409e6a4994d2beb347857 368 Gene3D G3DSA:3.40.50.410 200 364 2.4E-7 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_30295 cc5357c65227d12dda08f31c22599653 415 Pfam PF12666 PrgI family protein 6 94 3.9E-19 T 14-10-2018 IPR024414 Uncharacterised protein family PrgI A4R43_24830 43bf54bdcedb6cee3c9bba1fc3359063 290 Gene3D G3DSA:3.40.50.1390 86 220 1.6E-25 T 14-10-2018 A4R43_24830 43bf54bdcedb6cee3c9bba1fc3359063 290 SUPERFAMILY SSF53041 87 231 1.83E-23 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4R43_24830 43bf54bdcedb6cee3c9bba1fc3359063 290 Pfam PF00239 Resolvase, N terminal domain 88 232 9.8E-31 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4R43_24830 43bf54bdcedb6cee3c9bba1fc3359063 290 SMART SM00857 87 232 1.0E-26 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4R43_28830 cc087baf0e497d9f1e50aad1fee9d5a8 295 SUPERFAMILY SSF103481 31 133 5.95E-14 T 14-10-2018 A4R43_28830 cc087baf0e497d9f1e50aad1fee9d5a8 295 Pfam PF00892 EamA-like transporter family 149 276 5.8E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_28830 cc087baf0e497d9f1e50aad1fee9d5a8 295 Pfam PF00892 EamA-like transporter family 6 130 9.3E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_28830 cc087baf0e497d9f1e50aad1fee9d5a8 295 SUPERFAMILY SSF103481 178 280 2.88E-14 T 14-10-2018 A4R43_13225 0884ce8bb1142ea3f384e2392d2b32fb 491 Pfam PF00939 Sodium:sulfate symporter transmembrane region 29 481 1.6E-34 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 9.6E-37 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 9.6E-37 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 9.6E-37 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 9.6E-37 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.1E-51 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 Gene3D G3DSA:3.90.1170.10 2 138 5.4E-47 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 8.1E-46 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 SUPERFAMILY SSF54686 2 136 7.72E-54 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A4R43_33875 c6330d43b4988017c5c5b84a570eefa5 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 36.429 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_00725 133b84a6d27b624d83153ef0d1d5222a 311 SUPERFAMILY SSF46689 258 309 3.9E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00725 133b84a6d27b624d83153ef0d1d5222a 311 Pfam PF12833 Helix-turn-helix domain 228 306 1.4E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00725 133b84a6d27b624d83153ef0d1d5222a 311 Gene3D G3DSA:3.40.50.880 2 202 1.9E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_00725 133b84a6d27b624d83153ef0d1d5222a 311 SUPERFAMILY SSF52317 1 191 1.31E-45 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_00725 133b84a6d27b624d83153ef0d1d5222a 311 Gene3D G3DSA:1.10.10.60 206 310 3.9E-28 T 14-10-2018 A4R43_00725 133b84a6d27b624d83153ef0d1d5222a 311 SMART SM00342 222 305 7.8E-28 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_00725 133b84a6d27b624d83153ef0d1d5222a 311 Pfam PF01965 DJ-1/PfpI family 39 170 1.2E-15 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_00725 133b84a6d27b624d83153ef0d1d5222a 311 SUPERFAMILY SSF46689 208 255 1.7E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21510 300eb83082ff3477e0c3682114fe8a3a 365 Pfam PF01594 AI-2E family transporter 22 345 2.1E-57 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like A4R43_00940 5a6b0abca5adfb857dc261db7e907f51 250 Pfam PF01144 Coenzyme A transferase 6 232 1.1E-68 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_00940 5a6b0abca5adfb857dc261db7e907f51 250 Gene3D G3DSA:3.40.1080.10 2 233 3.5E-93 T 14-10-2018 A4R43_00940 5a6b0abca5adfb857dc261db7e907f51 250 SMART SM00882 4 233 8.2E-80 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_00940 5a6b0abca5adfb857dc261db7e907f51 250 SUPERFAMILY SSF100950 2 245 9.07E-83 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_00940 5a6b0abca5adfb857dc261db7e907f51 250 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 16 31 - T 14-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 A4R43_28690 b158903f5516e06e368b4e11489f7691 197 SUPERFAMILY SSF81296 30 197 1.23E-58 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_28690 b158903f5516e06e368b4e11489f7691 197 Gene3D G3DSA:2.70.50.50 30 197 1.5E-68 T 14-10-2018 A4R43_28690 b158903f5516e06e368b4e11489f7691 197 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 30 195 3.0E-39 T 14-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal A4R43_40520 2e746f0d4ec142c1446c31e87ae53c43 410 SUPERFAMILY SSF53850 38 407 4.55E-80 T 14-10-2018 A4R43_40520 2e746f0d4ec142c1446c31e87ae53c43 410 Gene3D G3DSA:3.40.190.10 39 409 4.9E-85 T 14-10-2018 A4R43_40520 2e746f0d4ec142c1446c31e87ae53c43 410 Pfam PF13416 Bacterial extracellular solute-binding protein 57 355 3.0E-46 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_02685 fa344e890611c7ccfc509475547a8cff 131 Gene3D G3DSA:3.30.750.24 12 120 5.1E-19 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_02685 fa344e890611c7ccfc509475547a8cff 131 SUPERFAMILY SSF52091 17 118 3.14E-14 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_02685 fa344e890611c7ccfc509475547a8cff 131 Pfam PF01740 STAS domain 19 116 2.5E-5 T 14-10-2018 IPR002645 STAS domain A4R43_14430 72ee0dbf7fa91f1fbf78a0cab6f21f76 431 Pfam PF13416 Bacterial extracellular solute-binding protein 62 362 3.7E-37 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_14430 72ee0dbf7fa91f1fbf78a0cab6f21f76 431 SUPERFAMILY SSF53850 21 429 1.68E-77 T 14-10-2018 A4R43_14430 72ee0dbf7fa91f1fbf78a0cab6f21f76 431 Gene3D G3DSA:3.40.190.10 60 386 7.3E-87 T 14-10-2018 A4R43_14430 72ee0dbf7fa91f1fbf78a0cab6f21f76 431 Gene3D G3DSA:3.40.190.10 159 424 7.3E-87 T 14-10-2018 A4R43_30545 900381ee92f63e9940f2ae252f7db92b 435 Gene3D G3DSA:3.30.565.10 307 435 5.4E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30545 900381ee92f63e9940f2ae252f7db92b 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 434 1.1E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_30545 900381ee92f63e9940f2ae252f7db92b 435 SUPERFAMILY SSF55874 329 434 1.22E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_29450 4fd623e28b866a00e9bc52224d203425 108 Gene3D G3DSA:1.10.1660.10 18 107 3.1E-23 T 14-10-2018 A4R43_29450 4fd623e28b866a00e9bc52224d203425 108 Pfam PF13591 MerR HTH family regulatory protein 21 101 2.1E-14 T 14-10-2018 A4R43_00600 ce59808c683887971551be4a0ba4e295 214 SUPERFAMILY SSF46689 9 82 2.41E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00600 ce59808c683887971551be4a0ba4e295 214 SUPERFAMILY SSF48498 87 212 2.89E-30 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_00600 ce59808c683887971551be4a0ba4e295 214 Gene3D G3DSA:1.10.357.10 2 213 7.3E-79 T 14-10-2018 A4R43_00600 ce59808c683887971551be4a0ba4e295 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 4.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_08750 d0525c2f28d87a27f2c57e1ee719b951 132 Gene3D G3DSA:3.10.180.10 1 121 4.6E-36 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_08750 d0525c2f28d87a27f2c57e1ee719b951 132 SUPERFAMILY SSF54593 1 121 1.19E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_08750 d0525c2f28d87a27f2c57e1ee719b951 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 118 4.1E-10 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_12815 e6fe11df6ea3c83040216fe0c8a9e3d1 334 PRINTS PR00412 Epoxide hydrolase signature 139 152 1.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_12815 e6fe11df6ea3c83040216fe0c8a9e3d1 334 PRINTS PR00412 Epoxide hydrolase signature 294 316 1.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_12815 e6fe11df6ea3c83040216fe0c8a9e3d1 334 PRINTS PR00412 Epoxide hydrolase signature 76 94 1.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_12815 e6fe11df6ea3c83040216fe0c8a9e3d1 334 Gene3D G3DSA:3.40.50.1820 48 317 2.5E-70 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12815 e6fe11df6ea3c83040216fe0c8a9e3d1 334 Pfam PF00561 alpha/beta hydrolase fold 70 305 3.3E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12815 e6fe11df6ea3c83040216fe0c8a9e3d1 334 SUPERFAMILY SSF53474 44 317 7.26E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 Pfam PF13191 AAA ATPase domain 10 167 1.5E-21 T 14-10-2018 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 Pfam PF00196 Bacterial regulatory proteins, luxR family 827 878 4.0E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 Gene3D G3DSA:1.10.10.10 800 881 2.8E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 SUPERFAMILY SSF52540 9 228 3.23E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 SMART SM00421 825 882 1.7E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 ProSitePatterns PS00622 LuxR-type HTH domain signature. 842 869 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 SUPERFAMILY SSF48452 631 792 3.11E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 842 858 1.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 828 842 1.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 858 870 1.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 Gene3D G3DSA:1.25.40.10 627 795 7.3E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_07430 9ad73cafc298ca19cb83bbfc65ddae3e 885 SUPERFAMILY SSF46894 815 878 3.3E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_40150 812ca39d6a66a78adf99ab20563bf9ce 395 SUPERFAMILY SSF89796 1 394 1.05E-130 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_40150 812ca39d6a66a78adf99ab20563bf9ce 395 Gene3D G3DSA:3.40.50.10540 3 388 1.5E-128 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_40150 812ca39d6a66a78adf99ab20563bf9ce 395 Pfam PF02515 CoA-transferase family III 4 371 1.1E-121 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_40150 812ca39d6a66a78adf99ab20563bf9ce 395 Gene3D G3DSA:3.30.1540.10 230 322 1.5E-128 T 14-10-2018 A4R43_16190 b8abfd70b667a8edcdcdbac52ce5ac2f 528 Pfam PF00474 Sodium:solute symporter family 44 453 3.0E-88 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_16190 b8abfd70b667a8edcdcdbac52ce5ac2f 528 Gene3D G3DSA:1.20.1730.10 30 524 1.8E-55 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_08655 d198c287aad5d0bfb84749d10cc6e5be 121 SUPERFAMILY SSF56784 6 109 1.97E-15 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_08655 d198c287aad5d0bfb84749d10cc6e5be 121 Gene3D G3DSA:3.40.50.1000 7 96 6.4E-20 T 14-10-2018 IPR023214 HAD superfamily A4R43_08655 d198c287aad5d0bfb84749d10cc6e5be 121 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 96 1.0E-5 T 14-10-2018 A4R43_09070 e0ce283c746c9c35d716f303db559aaa 543 SUPERFAMILY SSF53720 9 526 8.64E-126 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_09070 e0ce283c746c9c35d716f303db559aaa 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_09070 e0ce283c746c9c35d716f303db559aaa 543 Gene3D G3DSA:3.40.309.10 297 494 5.3E-201 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_09070 e0ce283c746c9c35d716f303db559aaa 543 Gene3D G3DSA:3.40.605.10 14 526 5.3E-201 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_09070 e0ce283c746c9c35d716f303db559aaa 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 11 540 1.1E-242 T 14-10-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 A4R43_09070 e0ce283c746c9c35d716f303db559aaa 543 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 292 299 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_09070 e0ce283c746c9c35d716f303db559aaa 543 Pfam PF00171 Aldehyde dehydrogenase family 55 525 2.5E-103 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_37225 80ba4b78836053a26ce6d1dfacd13d8e 260 Pfam PF00975 Thioesterase domain 19 242 9.2E-22 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_37225 80ba4b78836053a26ce6d1dfacd13d8e 260 SUPERFAMILY SSF53474 4 242 1.37E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_37225 80ba4b78836053a26ce6d1dfacd13d8e 260 Gene3D G3DSA:3.40.50.1820 4 243 4.7E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25970 66b775b431aad3b8935857ddc6008e62 263 Pfam PF05331 Protein of unknown function (DUF742) 152 262 1.5E-30 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_05630 51a50e9f7ede5ab5f9a38a781ba0a7df 129 SUPERFAMILY SSF52091 13 112 1.04E-16 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_05630 51a50e9f7ede5ab5f9a38a781ba0a7df 129 Pfam PF01740 STAS domain 16 110 1.3E-11 T 14-10-2018 IPR002645 STAS domain A4R43_05630 51a50e9f7ede5ab5f9a38a781ba0a7df 129 Gene3D G3DSA:3.30.750.24 6 118 2.8E-23 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_05630 51a50e9f7ede5ab5f9a38a781ba0a7df 129 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 17 112 1.1E-17 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_09785 239d8fbeb38d051d088cdf6801bc3eec 393 Pfam PF03583 Secretory lipase 132 391 7.3E-54 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_09785 239d8fbeb38d051d088cdf6801bc3eec 393 SUPERFAMILY SSF53474 86 364 7.21E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09785 239d8fbeb38d051d088cdf6801bc3eec 393 PIRSF PIRSF029171 1 393 3.5E-76 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_09785 239d8fbeb38d051d088cdf6801bc3eec 393 Gene3D G3DSA:1.10.260.130 229 318 2.1E-102 T 14-10-2018 A4R43_09785 239d8fbeb38d051d088cdf6801bc3eec 393 Gene3D G3DSA:3.40.50.1820 38 383 2.1E-102 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_31025 44701e0dd5e9cedcd8a6020091f65ecc 291 Pfam PF13845 Septum formation 34 129 8.9E-9 T 14-10-2018 IPR026004 Septum formation-related domain A4R43_31025 44701e0dd5e9cedcd8a6020091f65ecc 291 Pfam PF13845 Septum formation 68 268 6.0E-36 T 14-10-2018 IPR026004 Septum formation-related domain A4R43_01005 e1063cd7dec3a1483220597acb7572ef 78 SUPERFAMILY SSF47413 1 47 1.13E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_04790 e8819e91b32f8c3677988dabc999c24a 311 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 305 1.4E-68 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A4R43_04790 e8819e91b32f8c3677988dabc999c24a 311 Gene3D G3DSA:3.40.50.12230 1 310 5.4E-88 T 14-10-2018 A4R43_04790 e8819e91b32f8c3677988dabc999c24a 311 SUPERFAMILY SSF50486 205 310 2.04E-24 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 A4R43_04790 e8819e91b32f8c3677988dabc999c24a 311 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 305 31.443 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A4R43_04790 e8819e91b32f8c3677988dabc999c24a 311 SUPERFAMILY SSF53328 1 206 1.7E-55 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_04790 e8819e91b32f8c3677988dabc999c24a 311 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 6.2E-21 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_04790 e8819e91b32f8c3677988dabc999c24a 311 Pfam PF00551 Formyl transferase 2 179 1.4E-31 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4R43_17075 7bc592da0a231cfa2ed7acd1d44a6bd9 262 Gene3D G3DSA:3.20.20.30 2 241 8.6E-47 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_17075 7bc592da0a231cfa2ed7acd1d44a6bd9 262 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 9 258 8.0E-124 T 14-10-2018 IPR022480 F420-dependent oxidoreductase, MSMEG2906 A4R43_17075 7bc592da0a231cfa2ed7acd1d44a6bd9 262 Pfam PF00296 Luciferase-like monooxygenase 9 217 3.0E-34 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_17075 7bc592da0a231cfa2ed7acd1d44a6bd9 262 SUPERFAMILY SSF51679 6 217 2.06E-45 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_21210 0a6c61d2777b854b09311b21c72a00d6 394 Gene3D G3DSA:1.20.1250.20 11 196 1.0E-10 T 14-10-2018 A4R43_21210 0a6c61d2777b854b09311b21c72a00d6 394 Pfam PF07690 Major Facilitator Superfamily 237 382 1.5E-8 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_21210 0a6c61d2777b854b09311b21c72a00d6 394 Pfam PF07690 Major Facilitator Superfamily 26 222 5.9E-9 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_21210 0a6c61d2777b854b09311b21c72a00d6 394 Gene3D G3DSA:1.20.1250.20 209 391 6.2E-12 T 14-10-2018 A4R43_21210 0a6c61d2777b854b09311b21c72a00d6 394 SUPERFAMILY SSF103473 12 389 1.06E-28 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_30065 85cfbc5e702ce2300571dbf08bc64464 223 Pfam PF08281 Sigma-70, region 4 146 198 4.4E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_30065 85cfbc5e702ce2300571dbf08bc64464 223 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 200 4.0E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_30065 85cfbc5e702ce2300571dbf08bc64464 223 SUPERFAMILY SSF88946 31 135 1.37E-22 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_30065 85cfbc5e702ce2300571dbf08bc64464 223 Gene3D G3DSA:1.10.1740.10 25 113 6.8E-20 T 14-10-2018 A4R43_30065 85cfbc5e702ce2300571dbf08bc64464 223 SUPERFAMILY SSF88659 121 202 6.54E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_30065 85cfbc5e702ce2300571dbf08bc64464 223 Pfam PF04542 Sigma-70 region 2 49 113 5.1E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_30065 85cfbc5e702ce2300571dbf08bc64464 223 Gene3D G3DSA:1.10.10.10 127 203 3.7E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_24370 36b8736900a84242946ac85acd19e76c 248 SUPERFAMILY SSF51735 1 245 1.43E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_24370 36b8736900a84242946ac85acd19e76c 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 2.2E-49 T 14-10-2018 A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 5.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 5.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24370 36b8736900a84242946ac85acd19e76c 248 Gene3D G3DSA:3.40.50.720 3 248 6.8E-69 T 14-10-2018 A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24370 36b8736900a84242946ac85acd19e76c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_17485 c691408a2171beceb73f3ffe65e573c0 459 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 13 86 3.5E-19 T 14-10-2018 IPR024962 YukD-like A4R43_17485 c691408a2171beceb73f3ffe65e573c0 459 PIRSF PIRSF017804 3 459 1.4E-59 T 14-10-2018 IPR006707 Type VII secretion system membrane protein EccD A4R43_17485 c691408a2171beceb73f3ffe65e573c0 459 Gene3D G3DSA:3.10.20.90 8 87 1.7E-8 T 14-10-2018 A4R43_17485 c691408a2171beceb73f3ffe65e573c0 459 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 14 459 9.7E-55 T 14-10-2018 IPR006707 Type VII secretion system membrane protein EccD A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 Pfam PF00067 Cytochrome P450 303 380 8.6E-11 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 Gene3D G3DSA:1.10.630.10 6 408 5.3E-104 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 SUPERFAMILY SSF48264 11 408 1.83E-77 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 PRINTS PR00359 B-class P450 signature 139 155 4.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 PRINTS PR00359 B-class P450 signature 351 360 4.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 PRINTS PR00359 B-class P450 signature 194 216 4.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 PRINTS PR00359 B-class P450 signature 330 345 4.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 PRINTS PR00359 B-class P450 signature 92 103 4.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 PRINTS PR00359 B-class P450 signature 302 329 4.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 PRINTS PR00359 B-class P450 signature 360 371 4.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_24330 a3b26b84becd6ef2fefa137dac8ea69d 408 PRINTS PR00359 B-class P450 signature 156 171 4.4E-47 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_39650 b08eb29ccaf370ee67ce67290b36530a 118 Gene3D G3DSA:3.30.428.10 1 113 4.7E-33 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_39650 b08eb29ccaf370ee67ce67290b36530a 118 SUPERFAMILY SSF54197 4 110 2.63E-31 T 14-10-2018 IPR036265 HIT-like superfamily A4R43_39650 b08eb29ccaf370ee67ce67290b36530a 118 PRINTS PR00332 Histidine triad family signature 96 106 5.6E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein A4R43_39650 b08eb29ccaf370ee67ce67290b36530a 118 PRINTS PR00332 Histidine triad family signature 28 46 5.6E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein A4R43_39650 b08eb29ccaf370ee67ce67290b36530a 118 PRINTS PR00332 Histidine triad family signature 7 23 5.6E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein A4R43_39650 b08eb29ccaf370ee67ce67290b36530a 118 Pfam PF01230 HIT domain 14 110 4.2E-26 T 14-10-2018 IPR001310 Histidine triad (HIT) protein A4R43_25230 c1cb3ac1d54f64900ab8cdd7027d1331 105 Pfam PF13560 Helix-turn-helix domain 16 77 7.9E-7 T 14-10-2018 A4R43_25230 c1cb3ac1d54f64900ab8cdd7027d1331 105 SUPERFAMILY SSF47413 14 80 7.19E-7 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_25230 c1cb3ac1d54f64900ab8cdd7027d1331 105 SMART SM00530 19 78 0.0093 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_25230 c1cb3ac1d54f64900ab8cdd7027d1331 105 Gene3D G3DSA:1.10.260.40 14 104 1.8E-7 T 14-10-2018 A4R43_04310 2d2b0348b75e0040e092295d57abb953 249 Pfam PF01709 Transcriptional regulator 5 238 3.2E-89 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_04310 2d2b0348b75e0040e092295d57abb953 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 8.6E-99 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_04310 2d2b0348b75e0040e092295d57abb953 249 SUPERFAMILY SSF75625 3 247 2.22E-89 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_04310 2d2b0348b75e0040e092295d57abb953 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.702 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_04310 2d2b0348b75e0040e092295d57abb953 249 Gene3D G3DSA:3.30.70.980 132 206 5.0E-22 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_04310 2d2b0348b75e0040e092295d57abb953 249 Gene3D G3DSA:1.10.10.200 1 80 7.0E-32 T 14-10-2018 IPR017856 Integrase-like, N-terminal A4R43_04045 1d8db5f824b415d03564837b112d3dd3 274 SMART SM00382 32 224 2.0E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_04045 1d8db5f824b415d03564837b112d3dd3 274 SUPERFAMILY SSF52540 2 246 2.39E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04045 1d8db5f824b415d03564837b112d3dd3 274 Gene3D G3DSA:3.40.50.300 1 272 6.7E-88 T 14-10-2018 A4R43_04045 1d8db5f824b415d03564837b112d3dd3 274 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_04045 1d8db5f824b415d03564837b112d3dd3 274 Pfam PF00005 ABC transporter 25 175 2.2E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 Pfam PF03466 LysR substrate binding domain 90 293 3.7E-28 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 Gene3D G3DSA:3.40.190.290 94 299 2.9E-29 T 14-10-2018 A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 Gene3D G3DSA:1.10.10.10 6 85 3.0E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 6.8E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 SUPERFAMILY SSF53850 91 300 8.21E-30 T 14-10-2018 A4R43_00985 d8d2ed628483315049ddcc86ab19918b 302 SUPERFAMILY SSF46785 8 112 1.82E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 ProSitePatterns PS00321 recA signature. 215 223 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 SUPERFAMILY SSF54752 270 328 3.27E-21 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 Hamap MF_00268 Protein RecA [recA]. 7 331 52.564 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 Gene3D G3DSA:3.40.50.300 28 269 2.3E-82 T 14-10-2018 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 PRINTS PR00142 RecA protein signature 299 316 4.8E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 PRINTS PR00142 RecA protein signature 245 274 4.8E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 PRINTS PR00142 RecA protein signature 212 240 4.8E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 PRINTS PR00142 RecA protein signature 129 158 4.8E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 PRINTS PR00142 RecA protein signature 95 124 4.8E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 PRINTS PR00142 RecA protein signature 167 196 4.8E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 9.5E-173 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 SUPERFAMILY SSF52540 6 269 3.73E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 Gene3D G3DSA:3.30.250.10 270 347 1.9E-33 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 Pfam PF00154 recA bacterial DNA recombination protein 9 270 1.2E-142 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4R43_16965 d2e426c1117bdac9436432eb0b7e83b3 347 SMART SM00382 59 230 2.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_35365 e08e7fd4a7394a5b787c1f76f1147086 399 Pfam PF03583 Secretory lipase 128 395 1.2E-56 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_35365 e08e7fd4a7394a5b787c1f76f1147086 399 Gene3D G3DSA:1.10.260.130 233 324 2.8E-103 T 14-10-2018 A4R43_35365 e08e7fd4a7394a5b787c1f76f1147086 399 SUPERFAMILY SSF53474 91 364 2.1E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35365 e08e7fd4a7394a5b787c1f76f1147086 399 PIRSF PIRSF029171 2 399 7.8E-70 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4R43_35365 e08e7fd4a7394a5b787c1f76f1147086 399 Gene3D G3DSA:3.40.50.1820 38 389 2.8E-103 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_07195 da2638bf1a2f565eb8715823321da4ff 414 Pfam PF13556 PucR C-terminal helix-turn-helix domain 346 401 1.0E-14 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_07195 da2638bf1a2f565eb8715823321da4ff 414 Gene3D G3DSA:1.10.10.2840 278 407 2.8E-21 T 14-10-2018 A4R43_00540 5245e8b62feb2a961bf3113ec9d15589 341 SUPERFAMILY SSF46785 278 325 6.62E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00540 5245e8b62feb2a961bf3113ec9d15589 341 Pfam PF13556 PucR C-terminal helix-turn-helix domain 280 335 1.2E-9 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_00540 5245e8b62feb2a961bf3113ec9d15589 341 Gene3D G3DSA:1.10.10.2840 218 340 8.5E-12 T 14-10-2018 A4R43_12055 31df3b85961ab2b1d137f495b56d2dbc 423 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 6 344 4.3E-115 T 14-10-2018 IPR010839 Acyclic terpene utilisation A4R43_12835 4858bf6157b385a6a9dd806ec1bac0df 298 Pfam PF12833 Helix-turn-helix domain 184 258 4.5E-12 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_12835 4858bf6157b385a6a9dd806ec1bac0df 298 Gene3D G3DSA:1.10.10.60 166 262 6.2E-13 T 14-10-2018 A4R43_12835 4858bf6157b385a6a9dd806ec1bac0df 298 SMART SM00342 178 260 0.0027 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_18130 b984d83bef1696fe24c29cebb053ae7d 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 3.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_18130 b984d83bef1696fe24c29cebb053ae7d 231 Gene3D G3DSA:1.10.357.10 69 226 6.0E-51 T 14-10-2018 A4R43_18130 b984d83bef1696fe24c29cebb053ae7d 231 SUPERFAMILY SSF46689 21 94 1.13E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_18130 b984d83bef1696fe24c29cebb053ae7d 231 Gene3D G3DSA:1.10.10.60 19 68 1.3E-22 T 14-10-2018 A4R43_10495 ed6dbdfab48d05b9f144fec4d2b09a35 278 Gene3D G3DSA:3.40.1090.10 112 219 1.3E-14 T 14-10-2018 A4R43_10495 ed6dbdfab48d05b9f144fec4d2b09a35 278 Gene3D G3DSA:3.40.1090.10 1 64 4.0E-9 T 14-10-2018 A4R43_10495 ed6dbdfab48d05b9f144fec4d2b09a35 278 Pfam PF01734 Patatin-like phospholipase 6 197 1.5E-15 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A4R43_10495 ed6dbdfab48d05b9f144fec4d2b09a35 278 SUPERFAMILY SSF52151 4 218 2.62E-31 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4R43_35380 89261b87051458a156cccdb5c9f0f950 530 Gene3D G3DSA:3.40.50.1820 347 529 1.1E-5 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35380 89261b87051458a156cccdb5c9f0f950 530 Pfam PF06259 Alpha/beta hydrolase 304 472 4.8E-32 T 14-10-2018 IPR010427 Protein of unknown function DUF1023 A4R43_35380 89261b87051458a156cccdb5c9f0f950 530 SUPERFAMILY SSF53474 314 466 9.03E-8 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_10940 12fa6f0fa6b1fb49c17d4a65d37ea3d5 399 Gene3D G3DSA:1.20.1250.20 5 390 6.8E-35 T 14-10-2018 A4R43_10940 12fa6f0fa6b1fb49c17d4a65d37ea3d5 399 Pfam PF07690 Major Facilitator Superfamily 14 342 1.7E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_10940 12fa6f0fa6b1fb49c17d4a65d37ea3d5 399 SUPERFAMILY SSF103473 9 394 7.46E-41 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_36975 048e7424c5e83cb5edc9ccd3208a4962 219 SMART SM00448 2 113 1.4E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_36975 048e7424c5e83cb5edc9ccd3208a4962 219 Pfam PF00072 Response regulator receiver domain 4 114 9.8E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_36975 048e7424c5e83cb5edc9ccd3208a4962 219 SMART SM00862 147 218 5.4E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_36975 048e7424c5e83cb5edc9ccd3208a4962 219 SUPERFAMILY SSF52172 3 176 7.09E-36 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_36975 048e7424c5e83cb5edc9ccd3208a4962 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 218 1.5E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_36975 048e7424c5e83cb5edc9ccd3208a4962 219 Gene3D G3DSA:3.40.50.2300 1 121 1.3E-35 T 14-10-2018 A4R43_36975 048e7424c5e83cb5edc9ccd3208a4962 219 Gene3D G3DSA:1.10.10.10 126 219 1.8E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25305 b9b898cdbcf71ae40b28c49bc3d8d058 179 Pfam PF16157 Domain of unknown function (DUF4865) 1 172 3.0E-57 T 14-10-2018 IPR032349 Protein of unknown function DUF4865 A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 Gene3D G3DSA:2.80.10.50 31 81 2.1E-11 T 14-10-2018 A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 41 118 1.7E-20 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 125 186 7.8E-15 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 SUPERFAMILY SSF50370 38 178 4.73E-48 T 14-10-2018 IPR035992 Ricin B-like lectins A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 Pfam PF04616 Glycosyl hydrolases family 43 185 472 1.3E-53 T 14-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 SMART SM00458 41 178 1.1E-7 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 SUPERFAMILY SSF75005 184 489 2.75E-56 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 Gene3D G3DSA:2.115.10.20 179 480 1.8E-78 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 Gene3D G3DSA:2.80.10.50 82 126 4.2E-13 T 14-10-2018 A4R43_06925 89a23b37e88f825eb0964334b4dcdaac 492 Gene3D G3DSA:2.80.10.50 127 178 1.5E-13 T 14-10-2018 A4R43_13935 a56a2fd25d8c8f2e83dc55c7b3bac697 317 Pfam PF00491 Arginase family 36 307 4.5E-92 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_13935 a56a2fd25d8c8f2e83dc55c7b3bac697 317 Gene3D G3DSA:3.40.800.10 6 314 5.2E-115 T 14-10-2018 A4R43_13935 a56a2fd25d8c8f2e83dc55c7b3bac697 317 PIRSF PIRSF036979 14 314 4.2E-108 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_13935 a56a2fd25d8c8f2e83dc55c7b3bac697 317 SUPERFAMILY SSF52768 16 313 4.32E-101 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily A4R43_13935 a56a2fd25d8c8f2e83dc55c7b3bac697 317 PRINTS PR00116 Arginase signature 123 138 6.7E-14 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_13935 a56a2fd25d8c8f2e83dc55c7b3bac697 317 PRINTS PR00116 Arginase signature 236 265 6.7E-14 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 A4R43_13935 a56a2fd25d8c8f2e83dc55c7b3bac697 317 ProSitePatterns PS01053 Arginase family signature. 239 260 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A4R43_13935 a56a2fd25d8c8f2e83dc55c7b3bac697 317 TIGRFAM TIGR01230 agmatinase: agmatinase 33 308 4.4E-72 T 14-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A4R43_09115 b8722e9da7c1b2e8f013d4cbded82061 316 SUPERFAMILY SSF161098 23 312 4.06E-43 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_09115 b8722e9da7c1b2e8f013d4cbded82061 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 311 8.1E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_09115 b8722e9da7c1b2e8f013d4cbded82061 316 Gene3D G3DSA:1.10.3720.10 66 314 1.2E-50 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_39815 a8f5deae8f531e4539d40c762d992dc9 453 Gene3D G3DSA:1.20.1720.10 13 242 1.1E-40 T 14-10-2018 A4R43_39815 a8f5deae8f531e4539d40c762d992dc9 453 Pfam PF07690 Major Facilitator Superfamily 15 401 2.0E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_39815 a8f5deae8f531e4539d40c762d992dc9 453 SUPERFAMILY SSF103473 5 439 8.89E-54 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_39815 a8f5deae8f531e4539d40c762d992dc9 453 Gene3D G3DSA:1.20.1250.20 244 443 9.8E-10 T 14-10-2018 A4R43_00270 a05357a33d6f1a04531880fc5ef49020 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_00270 a05357a33d6f1a04531880fc5ef49020 233 SUPERFAMILY SSF52540 2 230 2.51E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_00270 a05357a33d6f1a04531880fc5ef49020 233 SMART SM00382 26 210 9.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_00270 a05357a33d6f1a04531880fc5ef49020 233 Gene3D G3DSA:3.40.50.300 1 233 4.0E-64 T 14-10-2018 A4R43_00270 a05357a33d6f1a04531880fc5ef49020 233 Pfam PF00005 ABC transporter 17 161 2.8E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_00270 a05357a33d6f1a04531880fc5ef49020 233 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 214 232 2.0E-4 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4R43_23240 50d487186e2d347c95e4fea34ad849a2 213 Hamap MF_00165 Thymidylate kinase [tmk]. 3 212 13.055 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4R43_23240 50d487186e2d347c95e4fea34ad849a2 213 Gene3D G3DSA:3.40.50.300 4 208 1.1E-52 T 14-10-2018 A4R43_23240 50d487186e2d347c95e4fea34ad849a2 213 SUPERFAMILY SSF52540 2 200 1.93E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_23240 50d487186e2d347c95e4fea34ad849a2 213 ProSitePatterns PS01331 Thymidylate kinase signature. 94 106 - T 14-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4R43_23240 50d487186e2d347c95e4fea34ad849a2 213 Pfam PF02223 Thymidylate kinase 7 187 2.0E-21 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A4R43_36580 40fe6d41a48eb0496efa4a11c2d5ffbb 491 Pfam PF04055 Radical SAM superfamily 80 253 1.1E-18 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_36580 40fe6d41a48eb0496efa4a11c2d5ffbb 491 Gene3D G3DSA:3.80.30.20 51 400 6.0E-56 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4R43_36580 40fe6d41a48eb0496efa4a11c2d5ffbb 491 SMART SM00729 73 302 6.0E-22 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4R43_36580 40fe6d41a48eb0496efa4a11c2d5ffbb 491 SUPERFAMILY SSF102114 53 477 4.58E-62 T 14-10-2018 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 Gene3D G3DSA:3.40.50.300 1 176 2.8E-6 T 14-10-2018 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 SMART SM00421 881 938 2.9E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 Gene3D G3DSA:1.10.10.10 881 936 4.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38335 12c2b8621d669a64e21675821b782b74 941 Pfam PF13191 AAA ATPase domain 2 164 8.5E-21 T 14-10-2018 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 SUPERFAMILY SSF52540 2 240 3.75E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_38335 12c2b8621d669a64e21675821b782b74 941 Gene3D G3DSA:1.25.40.10 559 873 2.1E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 ProSitePatterns PS00622 LuxR-type HTH domain signature. 898 925 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 SUPERFAMILY SSF46894 878 934 8.5E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 Pfam PF00196 Bacterial regulatory proteins, luxR family 883 934 1.2E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 884 898 4.7E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 898 914 4.7E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38335 12c2b8621d669a64e21675821b782b74 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 914 926 4.7E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30165 d9a18f2966e1c9739c175a09a4a1ba3e 470 Gene3D G3DSA:3.50.50.60 1 110 3.5E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30165 d9a18f2966e1c9739c175a09a4a1ba3e 470 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 56 9.9E-11 T 14-10-2018 A4R43_30165 d9a18f2966e1c9739c175a09a4a1ba3e 470 SUPERFAMILY SSF51905 2 468 3.02E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_36800 b19e1f768ec98767de4a2a279b482389 280 Pfam PF00722 Glycosyl hydrolases family 16 74 277 2.8E-43 T 14-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 A4R43_36800 b19e1f768ec98767de4a2a279b482389 280 SUPERFAMILY SSF49899 29 279 1.58E-74 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_36800 b19e1f768ec98767de4a2a279b482389 280 Gene3D G3DSA:2.60.120.200 38 280 5.3E-91 T 14-10-2018 A4R43_06490 4e65233cdeb0306a6f1bb2e675105de6 184 Pfam PF00857 Isochorismatase family 3 180 4.4E-23 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4R43_06490 4e65233cdeb0306a6f1bb2e675105de6 184 SUPERFAMILY SSF52499 3 182 1.11E-31 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_06490 4e65233cdeb0306a6f1bb2e675105de6 184 Gene3D G3DSA:3.40.50.850 1 184 5.2E-31 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_12800 de795331bf256e70233abe6909e3642d 226 Pfam PF02469 Fasciclin domain 99 222 3.7E-28 T 14-10-2018 IPR000782 FAS1 domain A4R43_12800 de795331bf256e70233abe6909e3642d 226 SMART SM00554 123 223 7.5E-24 T 14-10-2018 IPR000782 FAS1 domain A4R43_12800 de795331bf256e70233abe6909e3642d 226 SUPERFAMILY SSF82153 86 222 1.83E-28 T 14-10-2018 IPR036378 FAS1 domain superfamily A4R43_12800 de795331bf256e70233abe6909e3642d 226 Gene3D G3DSA:2.30.180.10 63 223 4.5E-38 T 14-10-2018 IPR036378 FAS1 domain superfamily A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 SUPERFAMILY SSF56235 1 157 1.54E-41 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 Gene3D G3DSA:3.60.20.10 1 166 1.2E-48 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 SUPERFAMILY SSF52402 190 441 9.12E-70 T 14-10-2018 A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 Pfam PF13537 Glutamine amidotransferase domain 25 140 1.8E-31 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 Gene3D G3DSA:3.40.50.620 190 473 1.3E-83 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 PIRSF PIRSF001589 1 359 7.4E-87 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 PIRSF PIRSF001589 337 465 5.3E-22 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 Pfam PF00733 Asparagine synthase 196 340 1.9E-49 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4R43_40680 10d59bb137dbbb7b6107c31073ff2761 487 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 1 340 2.5E-88 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_23555 7fecace800a3b932644a478c4a6f9d84 554 Gene3D G3DSA:3.40.190.10 274 536 3.7E-51 T 14-10-2018 A4R43_23555 7fecace800a3b932644a478c4a6f9d84 554 SUPERFAMILY SSF53850 272 539 1.09E-44 T 14-10-2018 A4R43_23555 7fecace800a3b932644a478c4a6f9d84 554 Gene3D G3DSA:3.40.190.10 347 494 3.7E-51 T 14-10-2018 A4R43_23555 7fecace800a3b932644a478c4a6f9d84 554 Pfam PF12849 PBP superfamily domain 266 525 1.1E-26 T 14-10-2018 IPR024370 PBP domain A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 Gene3D G3DSA:1.10.630.10 44 481 1.1E-106 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00465 E-class P450 group IV signature 373 387 3.2E-21 T 14-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00465 E-class P450 group IV signature 285 311 3.2E-21 T 14-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00465 E-class P450 group IV signature 389 407 3.2E-21 T 14-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00465 E-class P450 group IV signature 340 356 3.2E-21 T 14-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00465 E-class P450 group IV signature 414 430 3.2E-21 T 14-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00465 E-class P450 group IV signature 430 448 3.2E-21 T 14-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 SUPERFAMILY SSF48264 50 482 3.41E-98 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 423 432 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 Pfam PF00067 Cytochrome P450 58 203 2.0E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 Pfam PF00067 Cytochrome P450 254 456 5.6E-60 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00385 P450 superfamily signature 430 441 1.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00385 P450 superfamily signature 294 311 1.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00385 P450 superfamily signature 421 430 1.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05170 856dfa70ca84a7778835276c21dcf9c5 482 PRINTS PR00385 P450 superfamily signature 345 356 1.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_21195 f8bc8f7c04b5ed0a7eb53c949ff8bbf8 391 Pfam PF02515 CoA-transferase family III 4 368 1.4E-112 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_21195 f8bc8f7c04b5ed0a7eb53c949ff8bbf8 391 Gene3D G3DSA:3.30.1540.10 227 322 2.1E-119 T 14-10-2018 A4R43_21195 f8bc8f7c04b5ed0a7eb53c949ff8bbf8 391 SUPERFAMILY SSF89796 1 391 3.66E-122 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_21195 f8bc8f7c04b5ed0a7eb53c949ff8bbf8 391 Gene3D G3DSA:3.40.50.10540 3 385 2.1E-119 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_10400 65b3d6d3dd1caf39e8cf47edca104401 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 316 6.4E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_27325 b078a9cbce17f2a09dea896c3660f755 396 Pfam PF01139 tRNA-splicing ligase RtcB 28 396 5.5E-132 T 14-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4R43_27325 b078a9cbce17f2a09dea896c3660f755 396 Gene3D G3DSA:3.90.1860.10 2 396 6.9E-116 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4R43_27325 b078a9cbce17f2a09dea896c3660f755 396 SUPERFAMILY SSF103365 9 396 3.79E-130 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4R43_11265 52b8aef3586ca4a2cb10eee4fc60368b 205 Pfam PF01066 CDP-alcohol phosphatidyltransferase 21 85 3.1E-12 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4R43_11265 52b8aef3586ca4a2cb10eee4fc60368b 205 PIRSF PIRSF000847 16 202 7.5E-42 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A4R43_11265 52b8aef3586ca4a2cb10eee4fc60368b 205 Gene3D G3DSA:1.20.120.1760 9 128 3.3E-12 T 14-10-2018 A4R43_11265 52b8aef3586ca4a2cb10eee4fc60368b 205 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 Gene3D G3DSA:3.40.50.1980 174 298 1.2E-36 T 14-10-2018 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 Pfam PF01297 Zinc-uptake complex component A periplasmic 28 294 4.7E-69 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 Gene3D G3DSA:3.40.50.1980 25 173 2.3E-33 T 14-10-2018 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00691 Adhesin B signature 69 88 2.3E-22 T 14-10-2018 IPR006129 Adhesin B GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00691 Adhesin B signature 275 293 2.3E-22 T 14-10-2018 IPR006129 Adhesin B GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00691 Adhesin B signature 231 248 2.3E-22 T 14-10-2018 IPR006129 Adhesin B GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00691 Adhesin B signature 25 46 2.3E-22 T 14-10-2018 IPR006129 Adhesin B GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00691 Adhesin B signature 180 197 2.3E-22 T 14-10-2018 IPR006129 Adhesin B GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00690 Adhesin family signature 56 69 5.8E-25 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00690 Adhesin family signature 262 281 5.8E-25 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00690 Adhesin family signature 180 201 5.8E-25 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00690 Adhesin family signature 25 43 5.8E-25 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00690 Adhesin family signature 69 86 5.8E-25 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 PRINTS PR00690 Adhesin family signature 235 253 5.8E-25 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A4R43_03935 d864024cbf3633b95ac414e66f71309e 299 SUPERFAMILY SSF53807 12 296 2.26E-66 T 14-10-2018 A4R43_30360 c0bfaa44d2790f1ebb23bc9fabe93506 412 Pfam PF02371 Transposase IS116/IS110/IS902 family 276 359 8.8E-13 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_30360 c0bfaa44d2790f1ebb23bc9fabe93506 412 Pfam PF01548 Transposase 11 166 1.1E-34 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 325 1.3E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 343 1.3E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 1.3E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 Pfam PF00512 His Kinase A (phospho-acceptor) domain 121 188 4.7E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 SUPERFAMILY SSF55874 177 344 3.14E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 SMART SM00388 121 188 6.4E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 Gene3D G3DSA:1.10.287.130 113 193 7.8E-17 T 14-10-2018 A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 Gene3D G3DSA:3.30.565.10 194 345 1.9E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 SMART SM00387 233 345 1.3E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 236 344 7.0E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_24990 75e82884c2b9aedbf2f088891825c186 345 SUPERFAMILY SSF47384 109 188 3.34E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4R43_18975 32c835a07c07ad8fa994a074ed802bc7 386 SUPERFAMILY SSF55347 149 335 3.6E-28 T 14-10-2018 A4R43_18975 32c835a07c07ad8fa994a074ed802bc7 386 Gene3D G3DSA:3.40.50.720 4 143 1.2E-33 T 14-10-2018 A4R43_18975 32c835a07c07ad8fa994a074ed802bc7 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 53 141 1.5E-7 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_18975 32c835a07c07ad8fa994a074ed802bc7 386 SUPERFAMILY SSF51735 53 176 4.2E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_18975 32c835a07c07ad8fa994a074ed802bc7 386 Gene3D G3DSA:3.30.360.10 144 385 6.5E-63 T 14-10-2018 A4R43_25195 612e6c7b163d4a6fb96d8379ed36120f 431 SUPERFAMILY SSF140931 128 315 3.14E-27 T 14-10-2018 IPR036597 Fido-like domain superfamily A4R43_25195 612e6c7b163d4a6fb96d8379ed36120f 431 Gene3D G3DSA:1.10.3290.10 51 310 5.8E-38 T 14-10-2018 IPR036597 Fido-like domain superfamily A4R43_25195 612e6c7b163d4a6fb96d8379ed36120f 431 Pfam PF02661 Fic/DOC family 143 238 3.2E-18 T 14-10-2018 IPR003812 Fido domain A4R43_33345 6871dfdc869a93963b4ac50487b88eb8 212 SUPERFAMILY SSF51161 3 210 6.1E-33 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_33345 6871dfdc869a93963b4ac50487b88eb8 212 Gene3D G3DSA:3.40.50.20 1 88 4.3E-11 T 14-10-2018 A4R43_33345 6871dfdc869a93963b4ac50487b88eb8 212 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 5 207 5.1E-53 T 14-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like A4R43_33345 6871dfdc869a93963b4ac50487b88eb8 212 Gene3D G3DSA:2.160.10.10 89 212 5.7E-26 T 14-10-2018 A4R43_33345 6871dfdc869a93963b4ac50487b88eb8 212 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 158 191 4.7E-5 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 Pfam PF06441 Epoxide hydrolase N terminus 2 105 2.0E-34 T 14-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 Gene3D G3DSA:3.40.50.1820 1 378 4.1E-141 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 PIRSF PIRSF001112 1 378 2.0E-129 T 14-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 SUPERFAMILY SSF53474 3 375 1.02E-101 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 PRINTS PR00412 Epoxide hydrolase signature 350 372 2.2E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 PRINTS PR00412 Epoxide hydrolase signature 180 193 2.2E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 PRINTS PR00412 Epoxide hydrolase signature 166 179 2.2E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 PRINTS PR00412 Epoxide hydrolase signature 121 136 2.2E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_25130 ba1b79f23f81672c0e91c671f1fbf699 378 PRINTS PR00412 Epoxide hydrolase signature 96 114 2.2E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_07010 60e6cc6fbb33e58f746fd0baff99dcad 170 Gene3D G3DSA:2.80.10.50 36 169 1.3E-31 T 14-10-2018 A4R43_07010 60e6cc6fbb33e58f746fd0baff99dcad 170 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 119 168 1.7E-9 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_07010 60e6cc6fbb33e58f746fd0baff99dcad 170 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 36 113 1.6E-17 T 14-10-2018 IPR000772 Ricin B, lectin domain A4R43_07010 60e6cc6fbb33e58f746fd0baff99dcad 170 SUPERFAMILY SSF50370 39 168 1.87E-30 T 14-10-2018 IPR035992 Ricin B-like lectins A4R43_36820 87b163ed586a82d598ea73dd6bc334a1 500 Gene3D G3DSA:3.40.50.1820 2 500 8.8E-129 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_36820 87b163ed586a82d598ea73dd6bc334a1 500 SUPERFAMILY SSF53474 19 475 9.06E-106 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_36820 87b163ed586a82d598ea73dd6bc334a1 500 Pfam PF00135 Carboxylesterase family 19 471 1.3E-98 T 14-10-2018 IPR002018 Carboxylesterase, type B A4R43_22990 31e484a33c1f8e132ee60492b99e5e2e 235 PRINTS PR00400 Tetracycline repressor protein signature 215 229 5.9E-6 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_22990 31e484a33c1f8e132ee60492b99e5e2e 235 PRINTS PR00400 Tetracycline repressor protein signature 41 64 5.9E-6 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4R43_22990 31e484a33c1f8e132ee60492b99e5e2e 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 73 9.8E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22990 31e484a33c1f8e132ee60492b99e5e2e 235 Gene3D G3DSA:1.10.10.60 3 79 8.6E-27 T 14-10-2018 A4R43_22990 31e484a33c1f8e132ee60492b99e5e2e 235 SUPERFAMILY SSF48498 85 229 1.78E-25 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_22990 31e484a33c1f8e132ee60492b99e5e2e 235 SUPERFAMILY SSF46689 19 81 6.98E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22990 31e484a33c1f8e132ee60492b99e5e2e 235 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 87 230 2.6E-15 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_22990 31e484a33c1f8e132ee60492b99e5e2e 235 Gene3D G3DSA:1.10.357.10 80 232 1.5E-35 T 14-10-2018 A4R43_14225 47a74ceea1e2603e223aae06e48afa85 600 Gene3D G3DSA:3.40.50.300 1 233 2.2E-30 T 14-10-2018 A4R43_14225 47a74ceea1e2603e223aae06e48afa85 600 PIRSF PIRSF003128 1 579 5.7E-156 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A4R43_14225 47a74ceea1e2603e223aae06e48afa85 600 SUPERFAMILY SSF52540 2 221 2.72E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14225 47a74ceea1e2603e223aae06e48afa85 600 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 574 1.4E-172 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A4R43_14225 47a74ceea1e2603e223aae06e48afa85 600 SUPERFAMILY SSF52540 6 530 1.85E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14225 47a74ceea1e2603e223aae06e48afa85 600 Gene3D G3DSA:3.40.50.300 257 575 5.2E-54 T 14-10-2018 A4R43_14225 47a74ceea1e2603e223aae06e48afa85 600 Pfam PF02463 RecF/RecN/SMC N terminal domain 14 527 2.2E-12 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A4R43_35080 70f7d4265d6d603594ba11ed7478e6c4 248 Gene3D G3DSA:3.40.50.1580 4 245 3.4E-58 T 14-10-2018 A4R43_35080 70f7d4265d6d603594ba11ed7478e6c4 248 SUPERFAMILY SSF53167 7 242 9.69E-55 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A4R43_35080 70f7d4265d6d603594ba11ed7478e6c4 248 Pfam PF01048 Phosphorylase superfamily 19 240 4.0E-37 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4R43_40025 8509d1422fa04325f2e3d845e4fffd1a 189 SUPERFAMILY SSF109854 12 181 1.35E-13 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_40025 8509d1422fa04325f2e3d845e4fffd1a 189 Pfam PF12867 DinB superfamily 19 173 1.7E-14 T 14-10-2018 IPR024775 DinB-like domain A4R43_10610 83f23ebfe6612fede7382254a17fb905 118 Pfam PF01638 HxlR-like helix-turn-helix 19 106 2.4E-26 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_10610 83f23ebfe6612fede7382254a17fb905 118 Gene3D G3DSA:1.10.10.10 4 117 4.7E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10610 83f23ebfe6612fede7382254a17fb905 118 SUPERFAMILY SSF46785 14 111 9.26E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_34535 45db86aa14a8437a62bf618694e66697 198 Pfam PF00805 Pentapeptide repeats (8 copies) 129 167 3.1E-14 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_34535 45db86aa14a8437a62bf618694e66697 198 Gene3D G3DSA:2.160.20.100 8 198 8.4E-62 T 14-10-2018 A4R43_34535 45db86aa14a8437a62bf618694e66697 198 SUPERFAMILY SSF141571 20 196 6.57E-46 T 14-10-2018 A4R43_34535 45db86aa14a8437a62bf618694e66697 198 Pfam PF13599 Pentapeptide repeats (9 copies) 44 107 4.4E-8 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_19405 b339c70db7d93204f4dbe5cf8c65252f 352 Pfam PF02595 Glycerate kinase family 1 350 3.4E-104 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_19405 b339c70db7d93204f4dbe5cf8c65252f 352 PIRSF PIRSF006078 1 352 5.0E-103 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_19405 b339c70db7d93204f4dbe5cf8c65252f 352 Gene3D G3DSA:3.90.1510.10 26 253 7.3E-100 T 14-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 A4R43_19405 b339c70db7d93204f4dbe5cf8c65252f 352 SUPERFAMILY SSF110738 1 350 1.31E-96 T 14-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 A4R43_19405 b339c70db7d93204f4dbe5cf8c65252f 352 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 350 3.1E-100 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4R43_19405 b339c70db7d93204f4dbe5cf8c65252f 352 Gene3D G3DSA:3.40.50.10350 2 339 7.3E-100 T 14-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold A4R43_08380 c54d9317b7cce509e83745c4d646338d 206 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 53 60 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_08380 c54d9317b7cce509e83745c4d646338d 206 SUPERFAMILY SSF53056 5 198 7.85E-47 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A4R43_08380 c54d9317b7cce509e83745c4d646338d 206 Gene3D G3DSA:3.40.1050.10 1 202 2.6E-65 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A4R43_08380 c54d9317b7cce509e83745c4d646338d 206 SMART SM00947 41 199 4.5E-43 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_08380 c54d9317b7cce509e83745c4d646338d 206 Pfam PF00484 Carbonic anhydrase 48 194 3.5E-31 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4R43_03820 c3f0829de0f7e8a330338bb66a5ce313 1186 Gene3D G3DSA:2.60.120.260 842 939 7.8E-6 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_03820 c3f0829de0f7e8a330338bb66a5ce313 1186 Gene3D G3DSA:2.60.120.260 1055 1182 4.7E-12 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_03820 c3f0829de0f7e8a330338bb66a5ce313 1186 SUPERFAMILY SSF49785 1078 1180 1.03E-12 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_03820 c3f0829de0f7e8a330338bb66a5ce313 1186 Gene3D G3DSA:3.40.50.880 408 522 2.0E-5 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_00460 b1c694787e84210262de9ae684a43f51 205 Pfam PF13305 WHG domain 84 165 7.4E-15 T 14-10-2018 IPR025996 WHG domain A4R43_00460 b1c694787e84210262de9ae684a43f51 205 Gene3D G3DSA:1.10.357.10 3 183 7.8E-34 T 14-10-2018 A4R43_00460 b1c694787e84210262de9ae684a43f51 205 SUPERFAMILY SSF48498 81 173 9.37E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_00460 b1c694787e84210262de9ae684a43f51 205 SUPERFAMILY SSF46689 7 79 1.08E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_32915 dd9ea2503a14c63986a187e54a774829 271 Pfam PF06971 Putative DNA-binding protein N-terminus 50 97 4.6E-18 T 14-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 A4R43_32915 dd9ea2503a14c63986a187e54a774829 271 Pfam PF02629 CoA binding domain 126 223 2.5E-19 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_32915 dd9ea2503a14c63986a187e54a774829 271 Gene3D G3DSA:3.40.50.720 121 252 7.4E-44 T 14-10-2018 A4R43_32915 dd9ea2503a14c63986a187e54a774829 271 SMART SM00881 124 224 3.3E-16 T 14-10-2018 IPR003781 CoA-binding GO:0048037 A4R43_32915 dd9ea2503a14c63986a187e54a774829 271 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 45 253 34.417 T 14-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 A4R43_32915 dd9ea2503a14c63986a187e54a774829 271 SUPERFAMILY SSF51735 126 248 1.8E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_32915 dd9ea2503a14c63986a187e54a774829 271 SUPERFAMILY SSF46785 51 123 5.05E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_32915 dd9ea2503a14c63986a187e54a774829 271 Gene3D G3DSA:1.10.10.10 49 120 1.9E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15365 ce3f617456b6b6be51330b067a6d018f 139 Gene3D G3DSA:3.30.720.110 69 124 4.3E-25 T 14-10-2018 A4R43_15365 ce3f617456b6b6be51330b067a6d018f 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 118 9.0E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_15365 ce3f617456b6b6be51330b067a6d018f 139 Gene3D G3DSA:3.30.720.120 2 54 4.1E-17 T 14-10-2018 A4R43_15365 ce3f617456b6b6be51330b067a6d018f 139 SUPERFAMILY SSF54593 16 122 1.25E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_29850 ce30b0ba0cd375e4496cae054438c6f3 562 Gene3D G3DSA:1.20.1250.20 281 519 1.1E-19 T 14-10-2018 A4R43_29850 ce30b0ba0cd375e4496cae054438c6f3 562 SUPERFAMILY SSF103473 17 516 1.83E-68 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_29850 ce30b0ba0cd375e4496cae054438c6f3 562 PRINTS PR01036 Tetracycline resistance protein TetB signature 124 144 6.8E-8 T 14-10-2018 A4R43_29850 ce30b0ba0cd375e4496cae054438c6f3 562 PRINTS PR01036 Tetracycline resistance protein TetB signature 154 178 6.8E-8 T 14-10-2018 A4R43_29850 ce30b0ba0cd375e4496cae054438c6f3 562 PRINTS PR01036 Tetracycline resistance protein TetB signature 418 437 6.8E-8 T 14-10-2018 A4R43_29850 ce30b0ba0cd375e4496cae054438c6f3 562 PRINTS PR01036 Tetracycline resistance protein TetB signature 376 396 6.8E-8 T 14-10-2018 A4R43_29850 ce30b0ba0cd375e4496cae054438c6f3 562 Gene3D G3DSA:1.20.1720.10 31 238 1.5E-50 T 14-10-2018 A4R43_29850 ce30b0ba0cd375e4496cae054438c6f3 562 Pfam PF07690 Major Facilitator Superfamily 35 427 6.5E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_18460 a32d459990b514f1bf42647df5228b04 79 SUPERFAMILY SSF54814 18 63 2.35E-8 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4R43_18460 a32d459990b514f1bf42647df5228b04 79 Gene3D G3DSA:3.30.300.20 6 74 1.7E-5 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_18460 a32d459990b514f1bf42647df5228b04 79 Pfam PF13083 KH domain 6 66 3.8E-19 T 14-10-2018 A4R43_18460 a32d459990b514f1bf42647df5228b04 79 Hamap MF_00088 UPF0109 protein . 4 75 20.609 T 14-10-2018 IPR020627 Uncharacterised protein family UPF0109 A4R43_41485 18f2ac3dbd629c487b76af02a4157a82 79 Gene3D G3DSA:1.10.260.40 4 68 8.7E-22 T 14-10-2018 A4R43_41485 18f2ac3dbd629c487b76af02a4157a82 79 Pfam PF01381 Helix-turn-helix 12 60 7.7E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_41485 18f2ac3dbd629c487b76af02a4157a82 79 SUPERFAMILY SSF47413 3 67 9.12E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_41485 18f2ac3dbd629c487b76af02a4157a82 79 SMART SM00530 8 63 2.5E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_29000 0f74fb3581d399c219d8ffd9771f01f0 426 SUPERFAMILY SSF53383 41 417 8.11E-49 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_29000 0f74fb3581d399c219d8ffd9771f01f0 426 Gene3D G3DSA:3.40.640.10 66 308 1.2E-173 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_29000 0f74fb3581d399c219d8ffd9771f01f0 426 Pfam PF12897 Alanine-glyoxylate amino-transferase 21 424 6.9E-183 T 14-10-2018 IPR024551 Aminotransferase, putative A4R43_29000 0f74fb3581d399c219d8ffd9771f01f0 426 Gene3D G3DSA:3.90.1150.10 27 420 1.2E-173 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_39220 ae8ccc2b2a73bc9f2f66df593e5e9461 1089 Pfam PF09992 Phosphodiester glycosidase 232 386 6.7E-31 T 14-10-2018 IPR018711 Phosphodiester glycosidase A4R43_39220 ae8ccc2b2a73bc9f2f66df593e5e9461 1089 Pfam PF00149 Calcineurin-like phosphoesterase 750 914 1.1E-11 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_39220 ae8ccc2b2a73bc9f2f66df593e5e9461 1089 Gene3D G3DSA:3.60.21.10 747 995 1.3E-22 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_39220 ae8ccc2b2a73bc9f2f66df593e5e9461 1089 SUPERFAMILY SSF56300 748 983 1.82E-27 T 14-10-2018 A4R43_12155 bd6c04c3253833290819f5c998378cd2 589 Gene3D G3DSA:1.20.1260.20 29 191 7.2E-11 T 14-10-2018 IPR038332 PPE superfamily A4R43_12155 bd6c04c3253833290819f5c998378cd2 589 SUPERFAMILY SSF140459 31 189 5.23E-10 T 14-10-2018 A4R43_12155 bd6c04c3253833290819f5c998378cd2 589 Pfam PF00823 PPE family 38 177 1.1E-8 T 14-10-2018 IPR000030 PPE family A4R43_05450 ccfe97a7c70c9e8047f9f9f38dd1d4d7 132 Pfam PF00072 Response regulator receiver domain 13 123 4.9E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_05450 ccfe97a7c70c9e8047f9f9f38dd1d4d7 132 Gene3D G3DSA:3.40.50.12740 11 132 9.0E-28 T 14-10-2018 A4R43_05450 ccfe97a7c70c9e8047f9f9f38dd1d4d7 132 SUPERFAMILY SSF52172 11 127 3.98E-25 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_05450 ccfe97a7c70c9e8047f9f9f38dd1d4d7 132 SMART SM00448 11 122 1.4E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 SUPERFAMILY SSF103473 6 461 1.7E-62 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 Pfam PF07690 Major Facilitator Superfamily 19 413 9.5E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 426 4.2E-96 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 Gene3D G3DSA:1.20.1250.20 263 463 2.3E-19 T 14-10-2018 A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 1.5E-5 T 14-10-2018 A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 1.5E-5 T 14-10-2018 A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 1.5E-5 T 14-10-2018 A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 205 223 1.5E-5 T 14-10-2018 A4R43_09880 b5b5ef2827732eea82eecce2a681913c 466 Gene3D G3DSA:1.20.1720.10 16 244 5.3E-45 T 14-10-2018 A4R43_20150 b8a0f1f51e1c5e42b204c6d3c96303ab 274 Gene3D G3DSA:3.40.50.10170 1 143 2.3E-38 T 14-10-2018 A4R43_20150 b8a0f1f51e1c5e42b204c6d3c96303ab 274 Pfam PF02645 Uncharacterised protein, DegV family COG1307 1 272 2.1E-68 T 14-10-2018 IPR003797 DegV A4R43_20150 b8a0f1f51e1c5e42b204c6d3c96303ab 274 Gene3D G3DSA:3.30.1180.10 146 271 3.8E-34 T 14-10-2018 A4R43_20150 b8a0f1f51e1c5e42b204c6d3c96303ab 274 SUPERFAMILY SSF82549 1 270 2.04E-62 T 14-10-2018 A4R43_20150 b8a0f1f51e1c5e42b204c6d3c96303ab 274 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 1 270 1.5E-69 T 14-10-2018 IPR003797 DegV A4R43_32170 5f915e216c674746b2cbbd0e1d0f4a75 80 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 35 74 1.5E-6 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_32170 5f915e216c674746b2cbbd0e1d0f4a75 80 Gene3D G3DSA:3.30.530.20 7 80 5.8E-20 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_32170 5f915e216c674746b2cbbd0e1d0f4a75 80 SUPERFAMILY SSF55961 24 76 9.91E-16 T 14-10-2018 A4R43_14850 49ac5d20b4a0ff5cacca5e5edf27ca2e 147 SUPERFAMILY SSF46689 61 113 2.06E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14850 49ac5d20b4a0ff5cacca5e5edf27ca2e 147 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 62 104 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_14850 49ac5d20b4a0ff5cacca5e5edf27ca2e 147 Gene3D G3DSA:1.10.10.60 5 114 3.0E-30 T 14-10-2018 A4R43_14850 49ac5d20b4a0ff5cacca5e5edf27ca2e 147 SUPERFAMILY SSF46689 9 58 6.1E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14850 49ac5d20b4a0ff5cacca5e5edf27ca2e 147 SMART SM00342 25 108 5.8E-30 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_14850 49ac5d20b4a0ff5cacca5e5edf27ca2e 147 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 92 108 5.5E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_14850 49ac5d20b4a0ff5cacca5e5edf27ca2e 147 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 77 92 5.5E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_14850 49ac5d20b4a0ff5cacca5e5edf27ca2e 147 Pfam PF12833 Helix-turn-helix domain 31 110 1.6E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 184 502 1.2E-79 T 14-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 Gene3D G3DSA:3.20.20.80 184 526 3.5E-164 T 14-10-2018 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 SUPERFAMILY SSF55545 44 183 8.37E-25 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 47 181 2.8E-17 T 14-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 Gene3D G3DSA:3.30.379.10 48 183 3.5E-164 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 466 482 1.6E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 484 501 1.6E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 136 156 1.6E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 338 351 1.6E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 268 285 1.6E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 316 334 1.6E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 178 195 1.6E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 207 228 1.6E-47 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4R43_24165 fbd45c67f63239bf325f4c780aed8069 538 SUPERFAMILY SSF51445 184 531 2.81E-100 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_35465 ce7e37cc0bbe32e887e220afe1e0c152 302 Gene3D G3DSA:1.10.340.30 116 232 2.5E-17 T 14-10-2018 A4R43_35465 ce7e37cc0bbe32e887e220afe1e0c152 302 SUPERFAMILY SSF48150 104 281 2.51E-27 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4R43_12590 2c67d7150fdbfd753fc65c86a8b25c27 435 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 262 403 2.8E-8 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_12590 2c67d7150fdbfd753fc65c86a8b25c27 435 SUPERFAMILY SSF53756 1 429 2.71E-82 T 14-10-2018 A4R43_12590 2c67d7150fdbfd753fc65c86a8b25c27 435 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 56 1.3E-7 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_12590 2c67d7150fdbfd753fc65c86a8b25c27 435 Gene3D G3DSA:3.40.50.2000 243 414 1.2E-93 T 14-10-2018 A4R43_12590 2c67d7150fdbfd753fc65c86a8b25c27 435 Gene3D G3DSA:3.40.50.2000 2 242 1.2E-93 T 14-10-2018 A4R43_10945 8dfa9ac7c50830cb8fa89b4835a7c96d 195 SMART SM00418 14 93 3.4E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_10945 8dfa9ac7c50830cb8fa89b4835a7c96d 195 SUPERFAMILY SSF46785 12 87 9.24E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_10945 8dfa9ac7c50830cb8fa89b4835a7c96d 195 Gene3D G3DSA:1.10.10.10 10 133 7.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10945 8dfa9ac7c50830cb8fa89b4835a7c96d 195 Pfam PF12840 Helix-turn-helix domain 15 70 2.1E-12 T 14-10-2018 A4R43_33085 159961d9702fb0ef78076d2f9b8a7a3b 182 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 3.3E-70 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33085 159961d9702fb0ef78076d2f9b8a7a3b 182 SUPERFAMILY SSF56770 9 155 2.49E-67 T 14-10-2018 A4R43_33085 159961d9702fb0ef78076d2f9b8a7a3b 182 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33085 159961d9702fb0ef78076d2f9b8a7a3b 182 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 43.335 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33085 159961d9702fb0ef78076d2f9b8a7a3b 182 Gene3D G3DSA:3.40.50.12280 2 171 2.2E-75 T 14-10-2018 A4R43_33085 159961d9702fb0ef78076d2f9b8a7a3b 182 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 2.1E-24 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 Gene3D G3DSA:3.40.50.800 294 392 1.4E-13 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 Pfam PF03129 Anticodon binding domain 303 388 3.9E-5 T 14-10-2018 IPR004154 Anticodon-binding A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 Gene3D G3DSA:3.30.930.10 1 293 1.9E-96 T 14-10-2018 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 SUPERFAMILY SSF55681 3 288 6.89E-81 T 14-10-2018 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 SUPERFAMILY SSF52954 291 390 7.55E-16 T 14-10-2018 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 PRINTS PR01047 Threonyl-tRNA synthetase signature 91 119 2.0E-44 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 PRINTS PR01047 Threonyl-tRNA synthetase signature 269 282 2.0E-44 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 PRINTS PR01047 Threonyl-tRNA synthetase signature 124 147 2.0E-44 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 PRINTS PR01047 Threonyl-tRNA synthetase signature 296 308 2.0E-44 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 PRINTS PR01047 Threonyl-tRNA synthetase signature 226 254 2.0E-44 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 86 290 1.7E-29 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4R43_40230 7bcf6e388d488d22e72cb9ae2f37c6ce 392 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 3 384 2.6E-123 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4R43_16760 aa0798e71b255508f9719f1d2419a8a3 213 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 206 24.762 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 A4R43_16760 aa0798e71b255508f9719f1d2419a8a3 213 SUPERFAMILY SSF52218 1 211 1.32E-37 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_16760 aa0798e71b255508f9719f1d2419a8a3 213 Pfam PF02525 Flavodoxin-like fold 3 198 1.3E-30 T 14-10-2018 IPR003680 Flavodoxin-like fold A4R43_16760 aa0798e71b255508f9719f1d2419a8a3 213 Gene3D G3DSA:3.40.50.360 1 213 3.8E-44 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_18410 2c8c83a6749deb589592b9c84b921006 328 SUPERFAMILY SSF56349 132 324 1.82E-48 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_18410 2c8c83a6749deb589592b9c84b921006 328 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 14 327 52.618 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD A4R43_18410 2c8c83a6749deb589592b9c84b921006 328 SUPERFAMILY SSF47823 14 122 2.16E-11 T 14-10-2018 A4R43_18410 2c8c83a6749deb589592b9c84b921006 328 Gene3D G3DSA:1.10.443.10 135 321 4.9E-56 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4R43_18410 2c8c83a6749deb589592b9c84b921006 328 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 111 2.6E-13 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4R43_18410 2c8c83a6749deb589592b9c84b921006 328 Pfam PF00589 Phage integrase family 135 312 8.4E-43 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4R43_18410 2c8c83a6749deb589592b9c84b921006 328 Gene3D G3DSA:1.10.150.130 13 121 2.7E-14 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_06700 7f5d5545461f42dfd01fab1e760ab96c 119 Pfam PF05331 Protein of unknown function (DUF742) 7 119 1.2E-35 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_22640 dde24ae52ea2996948fd21d70b206433 186 SUPERFAMILY SSF48498 82 181 3.45E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_22640 dde24ae52ea2996948fd21d70b206433 186 SUPERFAMILY SSF46689 5 87 1.25E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22640 dde24ae52ea2996948fd21d70b206433 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22640 dde24ae52ea2996948fd21d70b206433 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22640 dde24ae52ea2996948fd21d70b206433 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 2.1E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22640 dde24ae52ea2996948fd21d70b206433 186 Gene3D G3DSA:1.10.357.10 1 186 6.8E-61 T 14-10-2018 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 PRINTS PR00359 B-class P450 signature 141 157 8.1E-41 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 PRINTS PR00359 B-class P450 signature 288 315 8.1E-41 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 PRINTS PR00359 B-class P450 signature 346 357 8.1E-41 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 PRINTS PR00359 B-class P450 signature 337 346 8.1E-41 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 PRINTS PR00359 B-class P450 signature 158 173 8.1E-41 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 PRINTS PR00359 B-class P450 signature 270 281 8.1E-41 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 PRINTS PR00359 B-class P450 signature 194 216 8.1E-41 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 PRINTS PR00359 B-class P450 signature 316 331 8.1E-41 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 SUPERFAMILY SSF48264 21 397 1.01E-73 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 Pfam PF00067 Cytochrome P450 269 365 2.3E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38465 7ac7479b553a094f11ce4e6bc782c541 397 Gene3D G3DSA:1.10.630.10 14 397 5.5E-97 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_35360 796bc235d52ac702e009ac86a4906943 326 SUPERFAMILY SSF53474 47 321 3.91E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35360 796bc235d52ac702e009ac86a4906943 326 Pfam PF00756 Putative esterase 58 310 8.9E-31 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A4R43_35360 796bc235d52ac702e009ac86a4906943 326 Gene3D G3DSA:3.40.50.1820 20 324 2.2E-82 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_26730 9c42493c85e43c3b27521ee13a602deb 266 Pfam PF01061 ABC-2 type transporter 23 230 2.4E-31 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_26730 9c42493c85e43c3b27521ee13a602deb 266 PIRSF PIRSF006648 1 266 2.5E-80 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_28020 650b4de9998a92fbc957ccc5e6be54f8 409 Gene3D G3DSA:1.10.260.40 13 72 3.8E-7 T 14-10-2018 A4R43_28020 650b4de9998a92fbc957ccc5e6be54f8 409 Gene3D G3DSA:1.25.40.10 156 368 1.6E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 SUPERFAMILY SSF51735 4 230 1.63E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 Gene3D G3DSA:3.40.50.720 2 239 1.0E-63 T 14-10-2018 A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 228 2.3E-50 T 14-10-2018 A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 7.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 7.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 212 7.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 7.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 176 7.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 66 77 2.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 157 2.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13365 9eaf038d159edbfac3a2ad9257dd9161 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 126 2.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_14420 fd1b5842f93611df1b62ade3717a1ac4 374 Pfam PF10282 Lactonase, 7-bladed beta-propeller 40 373 8.4E-92 T 14-10-2018 IPR019405 Lactonase, 7-bladed beta propeller A4R43_14420 fd1b5842f93611df1b62ade3717a1ac4 374 SUPERFAMILY SSF51004 85 354 1.91E-44 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily A4R43_14420 fd1b5842f93611df1b62ade3717a1ac4 374 Gene3D G3DSA:2.130.10.10 39 374 2.7E-98 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_39900 e24ff33eca329f82614dc00f7aae0c76 132 SUPERFAMILY SSF54211 6 110 8.34E-5 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4R43_39900 e24ff33eca329f82614dc00f7aae0c76 132 Gene3D G3DSA:3.30.230.10 2 115 1.6E-7 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 Gene3D G3DSA:3.40.50.1820 6 275 7.2E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 Pfam PF12697 Alpha/beta hydrolase family 27 268 6.1E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 SUPERFAMILY SSF53474 7 275 9.33E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 PRINTS PR00412 Epoxide hydrolase signature 111 124 4.5E-21 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 PRINTS PR00412 Epoxide hydrolase signature 251 273 4.5E-21 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 PRINTS PR00412 Epoxide hydrolase signature 97 110 4.5E-21 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 PRINTS PR00412 Epoxide hydrolase signature 31 49 4.5E-21 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 PRINTS PR00412 Epoxide hydrolase signature 51 66 4.5E-21 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_17985 e9dbce4105ee6dc84821319720e2eadb 277 PRINTS PR00412 Epoxide hydrolase signature 217 233 4.5E-21 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08000 6a73ed655580ec14a60300ceee5c4684 879 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 36 653 7.6E-80 T 14-10-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 A4R43_08000 6a73ed655580ec14a60300ceee5c4684 879 Gene3D G3DSA:2.60.120.610 46 213 4.3E-22 T 14-10-2018 IPR027451 Arabinofuranosyltransferase, domain 1 A4R43_08000 6a73ed655580ec14a60300ceee5c4684 879 Gene3D G3DSA:3.40.190.160 718 845 5.3E-11 T 14-10-2018 A4R43_07335 7ae5caa4778ac98f86c139eddf48657c 303 Gene3D G3DSA:3.90.25.10 164 296 5.7E-63 T 14-10-2018 A4R43_07335 7ae5caa4778ac98f86c139eddf48657c 303 Gene3D G3DSA:3.40.50.720 8 290 5.7E-63 T 14-10-2018 A4R43_07335 7ae5caa4778ac98f86c139eddf48657c 303 SUPERFAMILY SSF51735 8 266 2.52E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07335 7ae5caa4778ac98f86c139eddf48657c 303 Pfam PF05368 NmrA-like family 8 242 2.5E-39 T 14-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 A4R43_08820 e12a4823e89e6545b66c8dd54cf6433c 294 Pfam PF13460 NAD(P)H-binding 7 191 1.2E-20 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_08820 e12a4823e89e6545b66c8dd54cf6433c 294 Gene3D G3DSA:3.40.50.720 5 272 6.6E-56 T 14-10-2018 A4R43_08820 e12a4823e89e6545b66c8dd54cf6433c 294 Gene3D G3DSA:3.90.25.10 144 268 6.6E-56 T 14-10-2018 A4R43_08820 e12a4823e89e6545b66c8dd54cf6433c 294 SUPERFAMILY SSF51735 2 245 4.27E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11420 2af77422e199af91eae5b77e1a58dbb6 387 Gene3D G3DSA:3.20.20.300 63 386 5.3E-98 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A4R43_11420 2af77422e199af91eae5b77e1a58dbb6 387 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 71 382 1.4E-66 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4R43_11420 2af77422e199af91eae5b77e1a58dbb6 387 SUPERFAMILY SSF51445 90 383 2.63E-58 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_35595 37cdfaeb995a2bcc36b1f8fddcddd3b0 112 Gene3D G3DSA:1.10.10.10 1 105 4.8E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35595 37cdfaeb995a2bcc36b1f8fddcddd3b0 112 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 9.9E-23 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_35595 37cdfaeb995a2bcc36b1f8fddcddd3b0 112 SUPERFAMILY SSF46785 3 105 2.78E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20455 adc7ee95fa04c9873ce50b1d3e400c9a 410 SUPERFAMILY SSF52266 202 405 7.66E-45 T 14-10-2018 A4R43_20455 adc7ee95fa04c9873ce50b1d3e400c9a 410 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 207 400 3.4E-24 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_20455 adc7ee95fa04c9873ce50b1d3e400c9a 410 Gene3D G3DSA:3.40.50.1110 193 410 4.6E-34 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_24170 d3d41f1c12f2ba726381c8613970680f 191 SUPERFAMILY SSF46689 9 77 5.64E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_24170 d3d41f1c12f2ba726381c8613970680f 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_24170 d3d41f1c12f2ba726381c8613970680f 191 Gene3D G3DSA:1.10.10.60 3 53 9.0E-21 T 14-10-2018 A4R43_24170 d3d41f1c12f2ba726381c8613970680f 191 SUPERFAMILY SSF48498 86 189 3.16E-14 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_24170 d3d41f1c12f2ba726381c8613970680f 191 Gene3D G3DSA:1.10.357.10 54 191 7.7E-28 T 14-10-2018 A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 Pfam PF00005 ABC transporter 32 176 1.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 SUPERFAMILY SSF52540 263 502 5.59E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 Gene3D G3DSA:3.40.50.300 2 249 7.3E-59 T 14-10-2018 A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 SMART SM00382 39 224 2.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 SMART SM00382 290 491 5.6 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 Pfam PF00005 ABC transporter 281 442 6.1E-12 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 SUPERFAMILY SSF52540 13 236 2.6E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34755 a538176a00f2e05c312d4ea5e18e9a03 520 Gene3D G3DSA:3.40.50.300 262 510 8.6E-34 T 14-10-2018 A4R43_16040 253bf00c42cf9e3d0d374f2c26e1f1fd 282 Gene3D G3DSA:3.40.50.1820 2 279 2.3E-83 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16040 253bf00c42cf9e3d0d374f2c26e1f1fd 282 Pfam PF00561 alpha/beta hydrolase fold 28 266 1.0E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16040 253bf00c42cf9e3d0d374f2c26e1f1fd 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 4.5E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16040 253bf00c42cf9e3d0d374f2c26e1f1fd 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 4.5E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16040 253bf00c42cf9e3d0d374f2c26e1f1fd 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 4.5E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16040 253bf00c42cf9e3d0d374f2c26e1f1fd 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 4.5E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16040 253bf00c42cf9e3d0d374f2c26e1f1fd 282 SUPERFAMILY SSF53474 4 278 1.11E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41550 9716bfee7d6619b5cd1e590f22b6e02c 445 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 192 4.6E-17 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4R43_41550 9716bfee7d6619b5cd1e590f22b6e02c 445 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 269 430 9.3E-21 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A4R43_41550 9716bfee7d6619b5cd1e590f22b6e02c 445 SUPERFAMILY SSF52540 5 198 4.39E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41550 9716bfee7d6619b5cd1e590f22b6e02c 445 Gene3D G3DSA:3.40.50.300 44 194 2.8E-22 T 14-10-2018 A4R43_41550 9716bfee7d6619b5cd1e590f22b6e02c 445 SUPERFAMILY SSF52317 253 442 7.12E-28 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_41550 9716bfee7d6619b5cd1e590f22b6e02c 445 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 440 6.0E-117 T 14-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 A4R43_41550 9716bfee7d6619b5cd1e590f22b6e02c 445 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 4 432 40.392 T 14-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 A4R43_41550 9716bfee7d6619b5cd1e590f22b6e02c 445 Gene3D G3DSA:3.40.50.880 251 415 4.5E-8 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_40805 a5caf50abc210ce88cfbb39dd9656281 427 Gene3D G3DSA:3.40.630.10 10 264 2.2E-23 T 14-10-2018 A4R43_40805 a5caf50abc210ce88cfbb39dd9656281 427 Pfam PF01546 Peptidase family M20/M25/M40 105 413 1.8E-12 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_40805 a5caf50abc210ce88cfbb39dd9656281 427 SUPERFAMILY SSF53187 10 416 5.99E-26 T 14-10-2018 A4R43_17035 b0712a59c983dcf2a2378c03a18d2b48 557 Pfam PF05960 Bacterial protein of unknown function (DUF885) 24 553 1.6E-157 T 14-10-2018 IPR010281 Protein of unknown function DUF885 A4R43_01585 67706252f6663cca047c06fb11deca63 327 SUPERFAMILY SSF103481 213 312 3.14E-11 T 14-10-2018 A4R43_01585 67706252f6663cca047c06fb11deca63 327 Pfam PF00892 EamA-like transporter family 176 308 3.7E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_01585 67706252f6663cca047c06fb11deca63 327 Pfam PF00892 EamA-like transporter family 32 165 7.9E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_01585 67706252f6663cca047c06fb11deca63 327 SUPERFAMILY SSF103481 66 167 1.11E-10 T 14-10-2018 A4R43_40340 55f465011203b46e3ddee0a9031606df 185 Gene3D G3DSA:1.10.357.10 2 184 7.1E-11 T 14-10-2018 A4R43_40340 55f465011203b46e3ddee0a9031606df 185 SUPERFAMILY SSF46689 7 66 1.41E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_40380 dd539eae203dcd09120924cae6112b8f 198 SUPERFAMILY SSF52540 17 192 1.97E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_40380 dd539eae203dcd09120924cae6112b8f 198 Pfam PF03029 Conserved hypothetical ATP binding protein 23 190 3.6E-23 T 14-10-2018 IPR004130 GPN-loop GTPase A4R43_40380 dd539eae203dcd09120924cae6112b8f 198 Gene3D G3DSA:3.40.50.300 12 194 7.8E-14 T 14-10-2018 A4R43_25125 122dc8901450830bb76f538ae6e8c55e 397 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 71 82 7.5E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_25125 122dc8901450830bb76f538ae6e8c55e 397 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 41 49 7.5E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_25125 122dc8901450830bb76f538ae6e8c55e 397 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 124 138 7.5E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4R43_25125 122dc8901450830bb76f538ae6e8c55e 397 Pfam PF00561 alpha/beta hydrolase fold 39 157 1.5E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_25125 122dc8901450830bb76f538ae6e8c55e 397 SUPERFAMILY SSF53474 13 342 5.88E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25125 122dc8901450830bb76f538ae6e8c55e 397 Gene3D G3DSA:3.40.50.1820 21 396 2.2E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_34780 7e35b4058aad9393045c67a83e22365c 365 SUPERFAMILY SSF57997 72 290 4.51E-6 T 14-10-2018 A4R43_34780 7e35b4058aad9393045c67a83e22365c 365 Gene3D G3DSA:1.20.120.20 122 279 2.6E-8 T 14-10-2018 A4R43_22040 c1a94ed5f59764d41098e93650800295 447 Pfam PF10103 Zincin-like metallopeptidase 59 409 5.1E-118 T 14-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 A4R43_22040 c1a94ed5f59764d41098e93650800295 447 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 59 412 4.1E-118 T 14-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 A4R43_22040 c1a94ed5f59764d41098e93650800295 447 Gene3D G3DSA:1.20.150.30 58 192 5.3E-6 T 14-10-2018 A4R43_22040 c1a94ed5f59764d41098e93650800295 447 SUPERFAMILY SSF55486 58 413 8.79E-115 T 14-10-2018 A4R43_29350 6a0df0c2c38aa24029c1f73d4b2aacc9 149 Pfam PF00011 Hsp20/alpha crystallin family 39 137 1.6E-21 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4R43_29350 6a0df0c2c38aa24029c1f73d4b2aacc9 149 SUPERFAMILY SSF49764 10 137 5.23E-32 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_29350 6a0df0c2c38aa24029c1f73d4b2aacc9 149 Gene3D G3DSA:2.60.40.790 1 138 9.8E-30 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_03670 c7189ef9d374fed4cfdc21d7f34e9f1a 294 Gene3D G3DSA:1.10.12.10 222 277 1.3E-5 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_03670 c7189ef9d374fed4cfdc21d7f34e9f1a 294 SUPERFAMILY SSF52096 1 277 3.27E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_03670 c7189ef9d374fed4cfdc21d7f34e9f1a 294 Gene3D G3DSA:3.90.226.10 1 215 7.0E-65 T 14-10-2018 A4R43_03670 c7189ef9d374fed4cfdc21d7f34e9f1a 294 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 276 3.0E-48 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_08870 570a263138dabc188d072e336eeb297d 180 Gene3D G3DSA:3.40.50.360 1 179 9.3E-48 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_08870 570a263138dabc188d072e336eeb297d 180 SUPERFAMILY SSF52218 2 175 2.33E-37 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_08870 570a263138dabc188d072e336eeb297d 180 Pfam PF03358 NADPH-dependent FMN reductase 7 136 1.1E-31 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4R43_03385 8bbfcd4dbad33eed09d400fd9d6b6f93 109 Gene3D G3DSA:1.10.1660.10 10 81 1.1E-15 T 14-10-2018 A4R43_03385 8bbfcd4dbad33eed09d400fd9d6b6f93 109 SMART SM00422 15 83 3.7E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_03385 8bbfcd4dbad33eed09d400fd9d6b6f93 109 SUPERFAMILY SSF46955 15 102 2.33E-12 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_03385 8bbfcd4dbad33eed09d400fd9d6b6f93 109 Pfam PF13411 MerR HTH family regulatory protein 15 79 3.3E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00635 ae510eb2d305994c4c88414d94ceb2eb 160 Gene3D G3DSA:1.20.1290.10 14 147 9.5E-40 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_00635 ae510eb2d305994c4c88414d94ceb2eb 160 SUPERFAMILY SSF69118 19 144 2.22E-36 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_00635 ae510eb2d305994c4c88414d94ceb2eb 160 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 95 2.4E-20 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_00635 ae510eb2d305994c4c88414d94ceb2eb 160 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 79 1.1E-22 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 Gene3D G3DSA:3.40.50.880 1 196 6.6E-51 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 SUPERFAMILY SSF46689 255 304 1.36E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 SMART SM00342 218 301 2.6E-28 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 Gene3D G3DSA:1.10.10.60 202 306 1.3E-27 T 14-10-2018 A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 Pfam PF12833 Helix-turn-helix domain 224 302 1.6E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 Pfam PF01965 DJ-1/PfpI family 3 163 8.4E-16 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 255 297 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 SUPERFAMILY SSF52317 1 184 1.35E-43 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_21165 fcfcb49f0a156f0c0e76714f87e8bc17 306 SUPERFAMILY SSF46689 202 251 1.34E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_09975 3236a203d65af0ae65549863abf1108f 208 Pfam PF01865 Protein of unknown function DUF47 40 206 3.1E-22 T 14-10-2018 IPR018445 Putative phosphate transport regulator A4R43_09975 3236a203d65af0ae65549863abf1108f 208 Gene3D G3DSA:1.20.58.220 12 208 2.8E-50 T 14-10-2018 IPR038078 PhoU-like domain superfamily A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 SUPERFAMILY SSF50952 199 510 2.48E-13 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 Gene3D G3DSA:2.60.120.260 659 791 1.8E-33 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 Pfam PF16990 Carbohydrate binding module (family 35) 660 788 1.3E-11 T 14-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 SMART SM00758 29 169 3.7E-26 T 14-10-2018 IPR011658 PA14 domain A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 Pfam PF07691 PA14 domain 30 167 5.4E-21 T 14-10-2018 IPR011658 PA14 domain A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 Gene3D G3DSA:2.60.120.560 792 984 1.4E-33 T 14-10-2018 A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 Pfam PF06439 Domain of Unknown Function (DUF1080) 792 982 5.6E-31 T 14-10-2018 IPR010496 Domain of unknown function DUF1080 A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 SUPERFAMILY SSF49785 659 786 2.19E-22 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 SUPERFAMILY SSF56988 87 194 4.84E-10 T 14-10-2018 A4R43_10620 1e7005caea5d883be1266bfe34d6eb5a 985 Gene3D G3DSA:2.60.120.380 75 162 6.6E-10 T 14-10-2018 A4R43_14080 04f5cef3683a1905bba6907d9e87ce3e 253 Pfam PF00480 ROK family 8 166 1.0E-13 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_14080 04f5cef3683a1905bba6907d9e87ce3e 253 SUPERFAMILY SSF53067 7 248 4.23E-29 T 14-10-2018 A4R43_14080 04f5cef3683a1905bba6907d9e87ce3e 253 Gene3D G3DSA:3.30.420.40 2 104 1.6E-21 T 14-10-2018 A4R43_14080 04f5cef3683a1905bba6907d9e87ce3e 253 Gene3D G3DSA:3.30.420.40 111 250 3.7E-34 T 14-10-2018 A4R43_04095 f38003e59db70e25a1d5cebbeb73b8e3 265 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 32 259 1.7E-78 T 14-10-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 A4R43_04095 f38003e59db70e25a1d5cebbeb73b8e3 265 SUPERFAMILY SSF110710 10 263 6.28E-90 T 14-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like A4R43_33200 d41c4f2be0c1535f415ad0d172c8e34e 187 SUPERFAMILY SSF82607 10 93 3.01E-8 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_33200 d41c4f2be0c1535f415ad0d172c8e34e 187 Pfam PF02575 YbaB/EbfC DNA-binding family 14 95 2.5E-11 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_33200 d41c4f2be0c1535f415ad0d172c8e34e 187 Gene3D G3DSA:3.30.1310.10 6 108 4.3E-7 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_26520 b2775bbda0fea7467ed898da1c632310 361 SUPERFAMILY SSF55931 4 360 2.62E-86 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_26520 b2775bbda0fea7467ed898da1c632310 361 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 361 72.043 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_26520 b2775bbda0fea7467ed898da1c632310 361 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 9 289 4.0E-76 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_26520 b2775bbda0fea7467ed898da1c632310 361 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 10 286 7.8E-55 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_26520 b2775bbda0fea7467ed898da1c632310 361 Gene3D G3DSA:3.30.590.20 4 361 6.5E-112 T 14-10-2018 A4R43_17055 cc0b8fc7c174e40a607fc1dd22c87c53 186 SUPERFAMILY SSF160904 5 181 2.88E-37 T 14-10-2018 A4R43_17055 cc0b8fc7c174e40a607fc1dd22c87c53 186 Gene3D G3DSA:1.10.3300.10 3 183 5.3E-24 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_17055 cc0b8fc7c174e40a607fc1dd22c87c53 186 Pfam PF11706 CGNR zinc finger 140 182 5.9E-16 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_17055 cc0b8fc7c174e40a607fc1dd22c87c53 186 Pfam PF07336 Putative stress-induced transcription regulator 13 123 1.2E-12 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator A4R43_22535 c71648d609eb956d11f44724ac89f3b8 281 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 125 137 - T 14-10-2018 IPR033140 Lipase, GDXG, putative serine active site A4R43_22535 c71648d609eb956d11f44724ac89f3b8 281 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 59 75 - T 14-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 A4R43_22535 c71648d609eb956d11f44724ac89f3b8 281 Pfam PF07859 alpha/beta hydrolase fold 59 256 6.7E-52 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_22535 c71648d609eb956d11f44724ac89f3b8 281 Gene3D G3DSA:3.40.50.1820 2 280 1.8E-78 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22535 c71648d609eb956d11f44724ac89f3b8 281 SUPERFAMILY SSF53474 24 280 6.01E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_21665 5d6c6fbb03477c1c6b5a85fb727a7374 98 Gene3D G3DSA:3.40.50.300 10 94 2.0E-12 T 14-10-2018 A4R43_21665 5d6c6fbb03477c1c6b5a85fb727a7374 98 SUPERFAMILY SSF52540 13 85 2.12E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12540 369e7fabaff5daf697aefc7d7cdd831a 405 Gene3D G3DSA:1.10.606.20 22 403 1.1E-75 T 14-10-2018 A4R43_12540 369e7fabaff5daf697aefc7d7cdd831a 405 SUPERFAMILY SSF48317 7 396 9.68E-68 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4R43_12540 369e7fabaff5daf697aefc7d7cdd831a 405 Pfam PF01569 PAP2 superfamily 272 397 2.0E-13 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_36380 091d031bcc9d9a6d91c7b65b8ca8d4ee 200 Gene3D G3DSA:3.90.950.10 1 199 1.7E-71 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4R43_36380 091d031bcc9d9a6d91c7b65b8ca8d4ee 200 SUPERFAMILY SSF52972 3 197 5.76E-64 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4R43_36380 091d031bcc9d9a6d91c7b65b8ca8d4ee 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 194 1.5E-48 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A4R43_36380 091d031bcc9d9a6d91c7b65b8ca8d4ee 200 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 198 48.023 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A4R43_36380 091d031bcc9d9a6d91c7b65b8ca8d4ee 200 Pfam PF01725 Ham1 family 4 193 4.2E-57 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A4R43_20700 93d6acdf83bef195e58b7300179b6ae0 343 SUPERFAMILY SSF81301 5 130 7.44E-7 T 14-10-2018 A4R43_20700 93d6acdf83bef195e58b7300179b6ae0 343 Gene3D G3DSA:3.30.460.10 19 138 3.6E-5 T 14-10-2018 A4R43_35440 f663d9bffb65bbbeb25cf1f5afe02ace 373 Pfam PF00534 Glycosyl transferases group 1 186 334 2.4E-22 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_35440 f663d9bffb65bbbeb25cf1f5afe02ace 373 Pfam PF13439 Glycosyltransferase Family 4 16 171 1.1E-10 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_35440 f663d9bffb65bbbeb25cf1f5afe02ace 373 Gene3D G3DSA:3.40.50.2000 13 351 2.5E-48 T 14-10-2018 A4R43_35440 f663d9bffb65bbbeb25cf1f5afe02ace 373 SUPERFAMILY SSF53756 6 353 1.78E-60 T 14-10-2018 A4R43_35440 f663d9bffb65bbbeb25cf1f5afe02ace 373 Gene3D G3DSA:3.40.50.2000 171 338 2.5E-48 T 14-10-2018 A4R43_10335 f769fb07e8b37e88ee513f160df9d753 135 SUPERFAMILY SSF82784 3 133 1.7E-40 T 14-10-2018 IPR036102 OsmC/Ohr superfamily A4R43_10335 f769fb07e8b37e88ee513f160df9d753 135 Gene3D G3DSA:3.30.300.20 42 135 1.5E-31 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_10335 f769fb07e8b37e88ee513f160df9d753 135 Pfam PF02566 OsmC-like protein 36 132 5.1E-21 T 14-10-2018 IPR003718 OsmC/Ohr family A4R43_10335 f769fb07e8b37e88ee513f160df9d753 135 Gene3D G3DSA:2.20.25.10 1 41 3.1E-15 T 14-10-2018 A4R43_10335 f769fb07e8b37e88ee513f160df9d753 135 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 134 6.5E-51 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 A4R43_08395 34638a63ed698863fd9e4a6ab48a5183 474 Pfam PF11700 Vacuole effluxer Atg22 like 17 466 2.0E-89 T 14-10-2018 IPR024671 Autophagy-related protein 22-like A4R43_08395 34638a63ed698863fd9e4a6ab48a5183 474 SUPERFAMILY SSF103473 18 461 2.62E-36 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08395 34638a63ed698863fd9e4a6ab48a5183 474 Gene3D G3DSA:1.20.1250.20 188 465 5.4E-19 T 14-10-2018 A4R43_08395 34638a63ed698863fd9e4a6ab48a5183 474 Gene3D G3DSA:1.20.1250.20 4 187 7.0E-8 T 14-10-2018 A4R43_13555 1616d66eb05da7fd9e89886ff69771b9 252 SUPERFAMILY SSF47090 42 114 3.4E-20 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_13555 1616d66eb05da7fd9e89886ff69771b9 252 Pfam PF08291 Peptidase M15 124 237 3.2E-30 T 14-10-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 A4R43_13555 1616d66eb05da7fd9e89886ff69771b9 252 SUPERFAMILY SSF55166 123 248 1.69E-21 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_13555 1616d66eb05da7fd9e89886ff69771b9 252 Pfam PF01471 Putative peptidoglycan binding domain 54 112 3.1E-16 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_13555 1616d66eb05da7fd9e89886ff69771b9 252 Gene3D G3DSA:3.30.1380.10 124 252 3.8E-54 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_13555 1616d66eb05da7fd9e89886ff69771b9 252 Gene3D G3DSA:1.10.101.10 40 123 7.3E-32 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_04645 2f92569ef3647b2f742f31b248d0fb89 208 Gene3D G3DSA:1.10.10.1320 3 65 3.1E-23 T 14-10-2018 A4R43_04645 2f92569ef3647b2f742f31b248d0fb89 208 Pfam PF13490 Putative zinc-finger 12 37 1.3E-7 T 14-10-2018 IPR027383 Putative zinc-finger A4R43_02115 9ceded232194107af0897dd28b3b7ef9 310 Gene3D G3DSA:3.40.50.720 98 277 1.0E-92 T 14-10-2018 A4R43_02115 9ceded232194107af0897dd28b3b7ef9 310 Gene3D G3DSA:3.40.50.720 9 301 1.0E-92 T 14-10-2018 A4R43_02115 9ceded232194107af0897dd28b3b7ef9 310 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_02115 9ceded232194107af0897dd28b3b7ef9 310 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 303 1.9E-27 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_02115 9ceded232194107af0897dd28b3b7ef9 310 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 126 279 2.0E-47 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_02115 9ceded232194107af0897dd28b3b7ef9 310 SUPERFAMILY SSF52283 5 121 1.49E-26 T 14-10-2018 A4R43_02115 9ceded232194107af0897dd28b3b7ef9 310 SUPERFAMILY SSF51735 101 280 3.12E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_21380 e39a6bedc9bd972dc583fc59c489d9a5 191 Pfam PF01872 RibD C-terminal domain 5 183 5.2E-25 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_21380 e39a6bedc9bd972dc583fc59c489d9a5 191 Gene3D G3DSA:3.40.430.10 2 189 3.1E-36 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_21380 e39a6bedc9bd972dc583fc59c489d9a5 191 SUPERFAMILY SSF53597 4 190 2.38E-23 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_00440 924f80a15037ebee247cae2812c944ef 151 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 5 150 1.9E-32 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_00440 924f80a15037ebee247cae2812c944ef 151 PIRSF PIRSF005384 3 151 1.7E-43 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_00440 924f80a15037ebee247cae2812c944ef 151 Gene3D G3DSA:3.40.1400.10 2 151 1.4E-45 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_00440 924f80a15037ebee247cae2812c944ef 151 Pfam PF02502 Ribose/Galactose Isomerase 5 145 2.6E-43 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_00440 924f80a15037ebee247cae2812c944ef 151 SUPERFAMILY SSF89623 3 149 4.19E-47 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4R43_00440 924f80a15037ebee247cae2812c944ef 151 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 3 150 2.4E-60 T 14-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 A4R43_36145 e210e696fabca769c4badd620d0467a1 362 Pfam PF09362 Domain of unknown function (DUF1996) 98 340 7.5E-26 T 14-10-2018 IPR018535 Domain of unknown function DUF1996 A4R43_19185 8a5d70ec42201bf6437fd6bd119be9e6 481 Gene3D G3DSA:1.20.1740.10 29 473 1.0E-53 T 14-10-2018 A4R43_19185 8a5d70ec42201bf6437fd6bd119be9e6 481 PIRSF PIRSF006060 13 478 9.2E-68 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_19185 8a5d70ec42201bf6437fd6bd119be9e6 481 Pfam PF13520 Amino acid permease 33 448 3.3E-43 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_19185 8a5d70ec42201bf6437fd6bd119be9e6 481 TIGRFAM TIGR00908 2A0305: ethanolamine permease 22 469 5.3E-166 T 14-10-2018 IPR004757 Ethanolamine permease A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 Gene3D G3DSA:2.40.10.10 255 353 1.0E-75 T 14-10-2018 A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 Gene3D G3DSA:2.60.120.380 378 478 4.0E-8 T 14-10-2018 A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 Pfam PF02983 Alpha-lytic protease prodomain 113 170 1.8E-15 T 14-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 Gene3D G3DSA:3.30.300.50 30 113 2.3E-7 T 14-10-2018 IPR035070 Streptogrisin prodomain A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 SUPERFAMILY SSF50494 194 359 1.27E-32 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 331 345 3.8E-43 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 288 305 3.8E-43 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 307 330 3.8E-43 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 267 287 3.8E-43 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 211 225 3.8E-43 T 14-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 Gene3D G3DSA:3.30.300.50 114 180 2.1E-7 T 14-10-2018 IPR035070 Streptogrisin prodomain A4R43_11740 c97bdf24fdaefdeaab8f52e05529788b 478 Gene3D G3DSA:2.40.10.10 190 364 1.0E-75 T 14-10-2018 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 SUPERFAMILY SSF56059 3 221 9.12E-59 T 14-10-2018 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 Gene3D G3DSA:3.30.1490.20 21 96 3.7E-70 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 PIRSF PIRSF001554 1 373 5.8E-127 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 372 36.397 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 SUPERFAMILY SSF52210 224 371 3.27E-41 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 Gene3D G3DSA:3.40.50.261 224 372 7.9E-46 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 Gene3D G3DSA:3.30.470.20 3 212 3.7E-70 T 14-10-2018 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 241 265 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 Pfam PF08442 ATP-grasp domain 2 186 3.6E-55 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 Pfam PF00549 CoA-ligase 248 344 1.9E-12 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4R43_05760 909d1846c0665a3b6ba29993dd63d324 373 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 371 4.8E-116 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4R43_23420 1f3e854c9c6ea335f7adaaa0f246cb0d 101 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 2 93 20.514 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 A4R43_23420 1f3e854c9c6ea335f7adaaa0f246cb0d 101 SUPERFAMILY SSF55248 1 94 1.83E-28 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 A4R43_23420 1f3e854c9c6ea335f7adaaa0f246cb0d 101 Gene3D G3DSA:3.30.1360.20 4 99 1.1E-28 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 A4R43_23420 1f3e854c9c6ea335f7adaaa0f246cb0d 101 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 92 1.5E-27 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 A4R43_24565 45ec4d72b5a6463be2fce627bb6921ac 290 SUPERFAMILY SSF53335 31 270 5.09E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_24565 45ec4d72b5a6463be2fce627bb6921ac 290 PIRSF PIRSF017393 11 279 1.6E-66 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_24565 45ec4d72b5a6463be2fce627bb6921ac 290 Gene3D G3DSA:3.40.50.150 12 281 8.1E-77 T 14-10-2018 A4R43_24565 45ec4d72b5a6463be2fce627bb6921ac 290 Pfam PF04672 S-adenosyl methyltransferase 23 265 6.4E-61 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_22515 e9270cc8afa68bcbf7d90dffa24a1a88 199 Pfam PF01810 LysE type translocator 11 196 4.7E-32 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_22515 e9270cc8afa68bcbf7d90dffa24a1a88 199 PIRSF PIRSF006324 1 199 2.8E-42 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_03350 54d4fb3428a277e7ecaebf67984dacb5 302 Gene3D G3DSA:3.40.50.1100 51 144 7.2E-84 T 14-10-2018 A4R43_03350 54d4fb3428a277e7ecaebf67984dacb5 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 295 3.1E-63 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_03350 54d4fb3428a277e7ecaebf67984dacb5 302 Gene3D G3DSA:3.40.50.1100 12 299 7.2E-84 T 14-10-2018 A4R43_03350 54d4fb3428a277e7ecaebf67984dacb5 302 SUPERFAMILY SSF53686 8 299 3.01E-72 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_03350 54d4fb3428a277e7ecaebf67984dacb5 302 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 43 56 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4R43_13395 bcbf2c51704f8bd845c98b14da83400a 130 Gene3D G3DSA:3.10.450.50 1 127 2.9E-32 T 14-10-2018 A4R43_13395 bcbf2c51704f8bd845c98b14da83400a 130 SUPERFAMILY SSF54427 1 128 1.38E-34 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_13395 bcbf2c51704f8bd845c98b14da83400a 130 Pfam PF12680 SnoaL-like domain 8 113 8.3E-14 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_11815 60f558723e57a8ffca0e7221dd41e45f 268 Pfam PF02405 Permease MlaE 46 257 4.3E-60 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_14925 238b18e5b59dfc315b209896adb20564 299 Pfam PF01555 DNA methylase 14 90 3.5E-11 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4R43_14925 238b18e5b59dfc315b209896adb20564 299 Gene3D G3DSA:3.40.50.150 13 115 2.3E-13 T 14-10-2018 A4R43_14925 238b18e5b59dfc315b209896adb20564 299 SUPERFAMILY SSF53335 25 110 3.41E-15 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_14925 238b18e5b59dfc315b209896adb20564 299 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 62 80 2.4E-5 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_14925 238b18e5b59dfc315b209896adb20564 299 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 85 105 2.4E-5 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_14925 238b18e5b59dfc315b209896adb20564 299 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 43 60 2.4E-5 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4R43_28515 4949b46e70159b2d1112c5e464c5a6af 335 PIRSF PIRSF000267 1 333 3.0E-107 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4R43_28515 4949b46e70159b2d1112c5e464c5a6af 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 214 9.3E-69 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4R43_28515 4949b46e70159b2d1112c5e464c5a6af 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 2.1E-102 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4R43_11515 c76987bb060feadc9ad1fab7937a00cb 501 SUPERFAMILY SSF53474 71 458 1.08E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_11515 c76987bb060feadc9ad1fab7937a00cb 501 Pfam PF08386 TAP-like protein 370 470 6.7E-28 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_11515 c76987bb060feadc9ad1fab7937a00cb 501 Gene3D G3DSA:3.40.50.1820 308 460 8.6E-8 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 SUPERFAMILY SSF48264 16 397 7.6E-78 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 359 370 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 165 180 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 204 226 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 283 294 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 350 359 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 300 327 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 102 113 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 148 164 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 PRINTS PR00359 B-class P450 signature 328 343 1.3E-46 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 Gene3D G3DSA:1.10.630.10 2 408 3.9E-124 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_15925 c8a9da7dc9e7542960ce730399900240 408 Pfam PF00067 Cytochrome P450 287 375 1.2E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_24190 35057224cc198f67dd35aa9a0ef33ed9 489 Gene3D G3DSA:1.10.10.10 314 397 4.2E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_24190 35057224cc198f67dd35aa9a0ef33ed9 489 Gene3D G3DSA:3.30.450.40 32 215 3.2E-50 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_24190 35057224cc198f67dd35aa9a0ef33ed9 489 Pfam PF01590 GAF domain 97 212 1.1E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_24190 35057224cc198f67dd35aa9a0ef33ed9 489 SMART SM00862 321 386 1.0E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_13125 ab14d62619f6cb131e4c3e6aff343b08 203 SUPERFAMILY SSF46689 4 78 6.16E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_13125 ab14d62619f6cb131e4c3e6aff343b08 203 Gene3D G3DSA:1.10.357.10 1 201 1.0E-50 T 14-10-2018 A4R43_13125 ab14d62619f6cb131e4c3e6aff343b08 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 58 2.0E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_13125 ab14d62619f6cb131e4c3e6aff343b08 203 SUPERFAMILY SSF48498 90 201 1.67E-22 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_13125 ab14d62619f6cb131e4c3e6aff343b08 203 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 91 201 1.1E-25 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_12995 c34d1db6619681653e12544dafcfc43a 165 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 143 7.1E-29 T 14-10-2018 IPR019920 F420-binding domain, putative A4R43_12995 c34d1db6619681653e12544dafcfc43a 165 SUPERFAMILY SSF50475 5 149 7.14E-38 T 14-10-2018 A4R43_12995 c34d1db6619681653e12544dafcfc43a 165 Gene3D G3DSA:2.30.110.10 10 156 3.8E-43 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_12995 c34d1db6619681653e12544dafcfc43a 165 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 99 3.2E-19 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_09470 a8c858451faf15e10af7de4937801e23 466 Pfam PF07690 Major Facilitator Superfamily 11 266 2.0E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_09470 a8c858451faf15e10af7de4937801e23 466 Gene3D G3DSA:1.20.1250.20 250 453 3.4E-13 T 14-10-2018 A4R43_09470 a8c858451faf15e10af7de4937801e23 466 Gene3D G3DSA:1.20.1720.10 7 203 4.4E-24 T 14-10-2018 A4R43_09470 a8c858451faf15e10af7de4937801e23 466 SUPERFAMILY SSF103473 28 454 4.45E-40 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_09465 9433634b73a513c020e21edb8aebe39a 182 SUPERFAMILY SSF48498 62 176 7.42E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_09465 9433634b73a513c020e21edb8aebe39a 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 42 9.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09465 9433634b73a513c020e21edb8aebe39a 182 SUPERFAMILY SSF46689 4 63 1.39E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_09465 9433634b73a513c020e21edb8aebe39a 182 Gene3D G3DSA:1.10.357.10 2 179 6.8E-28 T 14-10-2018 A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 SUPERFAMILY SSF53474 34 299 1.34E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 1.4E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 1.4E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 PRINTS PR00412 Epoxide hydrolase signature 120 133 4.2E-15 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 PRINTS PR00412 Epoxide hydrolase signature 53 71 4.2E-15 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 PRINTS PR00412 Epoxide hydrolase signature 73 88 4.2E-15 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 PRINTS PR00412 Epoxide hydrolase signature 275 297 4.2E-15 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 Pfam PF00561 alpha/beta hydrolase fold 47 165 2.7E-19 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_28360 40a1f85020441f7c00bdd851d74e1bdb 309 Gene3D G3DSA:3.40.50.1820 2 299 1.1E-68 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09300 e98d578a37c60a9f664128a829aa1a11 112 Gene3D G3DSA:1.10.10.10 1 112 5.8E-40 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09300 e98d578a37c60a9f664128a829aa1a11 112 Pfam PF01638 HxlR-like helix-turn-helix 13 101 6.8E-27 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_09300 e98d578a37c60a9f664128a829aa1a11 112 SUPERFAMILY SSF46785 3 109 4.0E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_29825 d929f06a31899a6f792181ae755ecdb7 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 51 6.3E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_29825 d929f06a31899a6f792181ae755ecdb7 190 Gene3D G3DSA:1.10.357.10 1 189 2.9E-21 T 14-10-2018 A4R43_29825 d929f06a31899a6f792181ae755ecdb7 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_29825 d929f06a31899a6f792181ae755ecdb7 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_29825 d929f06a31899a6f792181ae755ecdb7 190 SUPERFAMILY SSF46689 2 70 7.28E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14250 3bc384daa8c832b450acda8d6db41b76 621 Gene3D G3DSA:1.25.40.10 441 620 1.2E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_14250 3bc384daa8c832b450acda8d6db41b76 621 SUPERFAMILY SSF48452 446 601 8.35E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_10310 271e615fdd8435e87f5216cc3dd4ff8d 175 Gene3D G3DSA:3.40.430.10 1 166 2.7E-35 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_10310 271e615fdd8435e87f5216cc3dd4ff8d 175 Pfam PF01872 RibD C-terminal domain 3 162 9.1E-20 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_10310 271e615fdd8435e87f5216cc3dd4ff8d 175 SUPERFAMILY SSF53597 4 155 3.27E-23 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_30500 4fb41fcb9c1006b7f317679915caf085 216 Pfam PF08281 Sigma-70, region 4 121 173 2.9E-17 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_30500 4fb41fcb9c1006b7f317679915caf085 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 176 9.5E-34 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_30500 4fb41fcb9c1006b7f317679915caf085 216 Pfam PF04542 Sigma-70 region 2 26 92 7.6E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_30500 4fb41fcb9c1006b7f317679915caf085 216 SUPERFAMILY SSF88946 6 106 2.35E-29 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_30500 4fb41fcb9c1006b7f317679915caf085 216 SUPERFAMILY SSF88659 114 178 8.04E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_30500 4fb41fcb9c1006b7f317679915caf085 216 Gene3D G3DSA:1.10.10.10 104 180 2.9E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_30500 4fb41fcb9c1006b7f317679915caf085 216 Gene3D G3DSA:1.10.1740.10 4 103 1.6E-28 T 14-10-2018 A4R43_14145 2ae7d34b8bd88adbb2e8e913285abf15 197 Gene3D G3DSA:3.40.50.300 9 188 3.6E-27 T 14-10-2018 A4R43_14145 2ae7d34b8bd88adbb2e8e913285abf15 197 SUPERFAMILY SSF52540 9 189 5.81E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14145 2ae7d34b8bd88adbb2e8e913285abf15 197 Pfam PF13238 AAA domain 12 141 2.8E-10 T 14-10-2018 A4R43_09030 8340c2b305f06dc4ae4d67df44a4ccf7 683 Gene3D G3DSA:1.10.1370.10 147 612 1.8E-251 T 14-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 A4R43_09030 8340c2b305f06dc4ae4d67df44a4ccf7 683 Gene3D G3DSA:1.10.1370.40 36 674 1.8E-251 T 14-10-2018 A4R43_09030 8340c2b305f06dc4ae4d67df44a4ccf7 683 SUPERFAMILY SSF55486 12 679 5.59E-172 T 14-10-2018 A4R43_09030 8340c2b305f06dc4ae4d67df44a4ccf7 683 Pfam PF01432 Peptidase family M3 231 679 3.3E-122 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A4R43_27015 60905ad654790ee2f45e328c49cce00a 178 Pfam PF00482 Type II secretion system (T2SS), protein F 43 161 1.0E-16 T 14-10-2018 IPR018076 Type II secretion system F domain A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 Gene3D G3DSA:3.30.470.20 139 188 2.0E-13 T 14-10-2018 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 SUPERFAMILY SSF56059 2 245 1.65E-74 T 14-10-2018 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 SUPERFAMILY SSF52009 702 808 4.58E-24 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 190 240 8.1E-11 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 53 185 6.9E-47 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 Gene3D G3DSA:3.50.30.10 704 809 2.8E-27 T 14-10-2018 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 Gene3D G3DSA:3.30.1490.20 48 138 1.4E-34 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 Gene3D G3DSA:3.30.1490.20 1 47 1.8E-7 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 Gene3D G3DSA:3.30.470.20 189 240 3.0E-12 T 14-10-2018 A4R43_01915 c07b893229e3ecc7a31e8b2763e34fd6 822 Pfam PF00391 PEP-utilising enzyme, mobile domain 732 803 1.5E-19 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4R43_35990 e113a71da7c0354b0bae0c5562de63f3 378 Pfam PF14258 Domain of unknown function (DUF4350) 51 112 1.4E-8 T 14-10-2018 IPR025646 Domain of unknown function DUF4350 A4R43_32780 a085a896687ba1c1e1ad347604cc4b96 189 SUPERFAMILY SSF46894 132 189 8.5E-6 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_32780 a085a896687ba1c1e1ad347604cc4b96 189 SMART SM00421 129 183 0.0019 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32780 a085a896687ba1c1e1ad347604cc4b96 189 Gene3D G3DSA:1.10.10.10 31 189 1.5E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_39390 922db1f388b71e081c899b9983ab8032 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 3.0E-20 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_39390 922db1f388b71e081c899b9983ab8032 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.314 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_39390 922db1f388b71e081c899b9983ab8032 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 7.8E-22 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_39390 922db1f388b71e081c899b9983ab8032 86 Pfam PF01649 Ribosomal protein S20 2 84 5.1E-26 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_39390 922db1f388b71e081c899b9983ab8032 86 SUPERFAMILY SSF46992 3 86 1.7E-27 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_39390 922db1f388b71e081c899b9983ab8032 86 Gene3D G3DSA:1.20.58.110 1 86 9.9E-28 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_38845 1933c66db10e9e9289757f555e3e4979 533 Gene3D G3DSA:3.20.20.80 17 465 1.8E-152 T 14-10-2018 A4R43_38845 1933c66db10e9e9289757f555e3e4979 533 Gene3D G3DSA:3.90.400.10 117 189 1.8E-152 T 14-10-2018 A4R43_38845 1933c66db10e9e9289757f555e3e4979 533 SMART SM00642 25 410 4.4E-111 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4R43_38845 1933c66db10e9e9289757f555e3e4979 533 Pfam PF11941 Domain of unknown function (DUF3459) 456 532 1.5E-10 T 14-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) A4R43_38845 1933c66db10e9e9289757f555e3e4979 533 SUPERFAMILY SSF51445 16 470 4.64E-121 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_38845 1933c66db10e9e9289757f555e3e4979 533 Pfam PF00128 Alpha amylase, catalytic domain 40 386 5.9E-80 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4R43_34745 f6bff7e65846ef9ec286231a227c5a21 148 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 26 129 1.4E-28 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34745 f6bff7e65846ef9ec286231a227c5a21 148 SUPERFAMILY SSF81343 23 132 5.72E-27 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34745 f6bff7e65846ef9ec286231a227c5a21 148 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 25 127 1.9E-22 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34745 f6bff7e65846ef9ec286231a227c5a21 148 Gene3D G3DSA:1.20.1300.10 26 137 5.8E-18 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_26950 0ba530759de78648de84f19e2e407b22 397 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 37 215 9.6E-58 T 14-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_26950 0ba530759de78648de84f19e2e407b22 397 SUPERFAMILY SSF52540 6 219 1.78E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26950 0ba530759de78648de84f19e2e407b22 397 Pfam PF13177 DNA polymerase III, delta subunit 36 180 2.2E-35 T 14-10-2018 A4R43_26950 0ba530759de78648de84f19e2e407b22 397 SMART SM00382 40 181 2.7E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26950 0ba530759de78648de84f19e2e407b22 397 Gene3D G3DSA:3.40.50.300 2 180 6.3E-45 T 14-10-2018 A4R43_00510 63cc87fdbe8f81643a3ff0530c855361 456 Pfam PF00144 Beta-lactamase 10 331 1.1E-67 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_00510 63cc87fdbe8f81643a3ff0530c855361 456 Gene3D G3DSA:3.40.710.10 5 348 2.6E-76 T 14-10-2018 A4R43_00510 63cc87fdbe8f81643a3ff0530c855361 456 SUPERFAMILY SSF56601 6 345 3.15E-78 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_04290 b659d43db71aab4fc5c99ef1ed05abaa 185 SMART SM00530 14 69 1.2E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_04290 b659d43db71aab4fc5c99ef1ed05abaa 185 SUPERFAMILY SSF51182 62 181 4.84E-19 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_04290 b659d43db71aab4fc5c99ef1ed05abaa 185 Gene3D G3DSA:1.10.260.40 2 79 3.8E-17 T 14-10-2018 A4R43_04290 b659d43db71aab4fc5c99ef1ed05abaa 185 Gene3D G3DSA:2.60.120.10 98 185 6.0E-15 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_04290 b659d43db71aab4fc5c99ef1ed05abaa 185 SUPERFAMILY SSF47413 10 73 2.56E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_04290 b659d43db71aab4fc5c99ef1ed05abaa 185 Pfam PF01381 Helix-turn-helix 15 68 2.3E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 Pfam PF03466 LysR substrate binding domain 89 288 2.2E-31 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 SUPERFAMILY SSF46785 4 88 9.09E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 SUPERFAMILY SSF53850 89 292 4.96E-32 T 14-10-2018 A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 Gene3D G3DSA:3.40.190.10 164 269 7.8E-46 T 14-10-2018 A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 Gene3D G3DSA:1.10.10.10 1 86 6.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.3E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 7.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 7.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 7.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_10105 7472be3735a566e82fc6b0ce89aad541 297 Gene3D G3DSA:3.40.190.10 90 287 7.8E-46 T 14-10-2018 A4R43_40750 239996640b0850113f24c880c9ba63fa 266 Pfam PF11251 Protein of unknown function (DUF3050) 28 251 1.3E-77 T 14-10-2018 IPR024423 Protein of unknown function DUF3050 A4R43_40750 239996640b0850113f24c880c9ba63fa 266 Gene3D G3DSA:1.20.910.10 14 256 2.5E-32 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_22830 d89c43c7f94c3032359a2e295cd1464e 242 Gene3D G3DSA:3.60.40.10 13 239 1.5E-30 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_22830 d89c43c7f94c3032359a2e295cd1464e 242 SUPERFAMILY SSF81606 18 239 6.41E-29 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_22830 d89c43c7f94c3032359a2e295cd1464e 242 SMART SM00332 6 236 2.7E-5 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_22830 d89c43c7f94c3032359a2e295cd1464e 242 Pfam PF13672 Protein phosphatase 2C 23 197 1.6E-5 T 14-10-2018 A4R43_22830 d89c43c7f94c3032359a2e295cd1464e 242 SMART SM00331 25 238 0.0016 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_31235 06e8fe5a348b6b5b4f126b987ab9e1de 178 SMART SM00986 10 173 4.6E-10 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_31235 06e8fe5a348b6b5b4f126b987ab9e1de 178 SMART SM00987 10 173 4.6E-10 T 14-10-2018 A4R43_31235 06e8fe5a348b6b5b4f126b987ab9e1de 178 Pfam PF03167 Uracil DNA glycosylase superfamily 13 162 2.1E-25 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_31235 06e8fe5a348b6b5b4f126b987ab9e1de 178 Gene3D G3DSA:3.40.470.10 9 174 2.1E-62 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_31235 06e8fe5a348b6b5b4f126b987ab9e1de 178 SUPERFAMILY SSF52141 11 166 6.21E-41 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_29140 ab32c768882e583bb4023f40597df36f 88 Pfam PF06781 Cell division protein CrgA 1 88 2.7E-39 T 14-10-2018 IPR009619 Cell division protein CrgA A4R43_29140 ab32c768882e583bb4023f40597df36f 88 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 88 23.955 T 14-10-2018 IPR009619 Cell division protein CrgA A4R43_41225 168096eddc105b07aa1764eb73ab803b 130 SUPERFAMILY SSF55021 3 61 2.2E-9 T 14-10-2018 A4R43_41225 168096eddc105b07aa1764eb73ab803b 130 SUPERFAMILY SSF55021 64 127 6.11E-17 T 14-10-2018 A4R43_41225 168096eddc105b07aa1764eb73ab803b 130 PIRSF PIRSF008459 2 130 6.0E-29 T 14-10-2018 IPR016540 Uncharacterised conserved protein UCP008459 A4R43_41225 168096eddc105b07aa1764eb73ab803b 130 Gene3D G3DSA:3.30.2130.10 2 130 3.0E-41 T 14-10-2018 A4R43_41225 168096eddc105b07aa1764eb73ab803b 130 Pfam PF13840 ACT domain 61 122 3.9E-19 T 14-10-2018 IPR027795 CASTOR, ACT domain A4R43_06045 f4f371b94f5135a017e411d7e1620301 254 Pfam PF00440 Bacterial regulatory proteins, tetR family 60 104 4.8E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06045 f4f371b94f5135a017e411d7e1620301 254 SUPERFAMILY SSF46689 50 113 2.05E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_06045 f4f371b94f5135a017e411d7e1620301 254 Gene3D G3DSA:1.10.357.10 109 247 1.1E-26 T 14-10-2018 A4R43_06045 f4f371b94f5135a017e411d7e1620301 254 Gene3D G3DSA:1.10.10.60 30 108 1.0E-11 T 14-10-2018 A4R43_06045 f4f371b94f5135a017e411d7e1620301 254 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 119 246 1.1E-7 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4R43_06045 f4f371b94f5135a017e411d7e1620301 254 SUPERFAMILY SSF48498 118 248 1.87E-18 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_23975 b98c53e886e3d010b20355f792a33a4b 407 SUPERFAMILY SSF50952 51 397 5.89E-32 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_23975 b98c53e886e3d010b20355f792a33a4b 407 Pfam PF07995 Glucose / Sorbosone dehydrogenase 60 402 1.8E-74 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_23975 b98c53e886e3d010b20355f792a33a4b 407 Gene3D G3DSA:2.120.10.30 40 407 2.3E-88 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_30440 5c651cc5e4c9e9686974a6fe25bb0227 387 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 32 256 1.3E-54 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_30440 5c651cc5e4c9e9686974a6fe25bb0227 387 Pfam PF02096 60Kd inner membrane protein 32 257 3.2E-52 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4R43_07635 7b155f6008469993833040b7c5ec94f6 460 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 103 437 4.9E-24 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A4R43_07635 7b155f6008469993833040b7c5ec94f6 460 SUPERFAMILY SSF53756 8 451 5.93E-63 T 14-10-2018 A4R43_07635 7b155f6008469993833040b7c5ec94f6 460 Gene3D G3DSA:3.40.50.2000 2 271 9.5E-19 T 14-10-2018 A4R43_07635 7b155f6008469993833040b7c5ec94f6 460 Gene3D G3DSA:3.40.50.2000 272 440 8.3E-35 T 14-10-2018 A4R43_19260 99fe68b5f9db943332a677087df323f9 107 Gene3D G3DSA:3.30.70.1060 1 107 4.9E-35 T 14-10-2018 A4R43_19260 99fe68b5f9db943332a677087df323f9 107 SUPERFAMILY SSF54909 1 105 4.29E-29 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_19260 99fe68b5f9db943332a677087df323f9 107 Pfam PF03795 YCII-related domain 1 105 2.7E-20 T 14-10-2018 IPR005545 YCII-related A4R43_29610 4796efe888623ad818e889fc483bf5a1 237 SUPERFAMILY SSF52402 15 234 7.06E-59 T 14-10-2018 A4R43_29610 4796efe888623ad818e889fc483bf5a1 237 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 15 232 46.358 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4R43_29610 4796efe888623ad818e889fc483bf5a1 237 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 18 219 7.4E-56 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4R43_29610 4796efe888623ad818e889fc483bf5a1 237 PIRSF PIRSF006293 13 237 5.2E-71 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4R43_29610 4796efe888623ad818e889fc483bf5a1 237 Pfam PF06508 Queuosine biosynthesis protein QueC 17 225 1.8E-60 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4R43_29610 4796efe888623ad818e889fc483bf5a1 237 Gene3D G3DSA:3.40.50.620 14 234 5.3E-69 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_39460 15483d49a1f6a04917ca1ed23bea6b57 336 Pfam PF12697 Alpha/beta hydrolase family 61 305 7.0E-21 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_39460 15483d49a1f6a04917ca1ed23bea6b57 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 100 5.7E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_39460 15483d49a1f6a04917ca1ed23bea6b57 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 130 143 5.7E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_39460 15483d49a1f6a04917ca1ed23bea6b57 336 Gene3D G3DSA:3.40.50.1820 44 322 1.2E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_39460 15483d49a1f6a04917ca1ed23bea6b57 336 PRINTS PR00412 Epoxide hydrolase signature 65 83 1.7E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_39460 15483d49a1f6a04917ca1ed23bea6b57 336 PRINTS PR00412 Epoxide hydrolase signature 85 100 1.7E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_39460 15483d49a1f6a04917ca1ed23bea6b57 336 PRINTS PR00412 Epoxide hydrolase signature 288 310 1.7E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_39460 15483d49a1f6a04917ca1ed23bea6b57 336 SUPERFAMILY SSF53474 56 312 5.64E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03015 d842f56c18561251c0b21806f49ede87 147 SUPERFAMILY SSF55874 44 129 6.32E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03015 d842f56c18561251c0b21806f49ede87 147 Gene3D G3DSA:3.30.565.10 13 133 2.5E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03015 d842f56c18561251c0b21806f49ede87 147 Pfam PF13581 Histidine kinase-like ATPase domain 25 113 1.8E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 2.8E-25 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 Pfam PF00120 Glutamine synthetase, catalytic domain 107 441 3.5E-127 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 SMART SM01230 106 357 2.4E-126 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 Gene3D G3DSA:3.30.590.10 109 445 2.1E-122 T 14-10-2018 A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 SUPERFAMILY SSF54368 8 104 6.41E-28 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 442 3.4E-136 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 SUPERFAMILY SSF55931 108 444 8.63E-118 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4R43_22150 7fe7b1af2c2a06f7f5e2dfa461a6559a 447 Gene3D G3DSA:3.10.20.70 2 108 1.2E-33 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_26775 073770ded1c3d2cdebc0c649e6d047e9 300 SUPERFAMILY SSF51735 9 173 5.04E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_26775 073770ded1c3d2cdebc0c649e6d047e9 300 SUPERFAMILY SSF48179 176 273 5.44E-25 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_26775 073770ded1c3d2cdebc0c649e6d047e9 300 Gene3D G3DSA:3.40.50.720 6 173 9.8E-37 T 14-10-2018 A4R43_26775 073770ded1c3d2cdebc0c649e6d047e9 300 Pfam PF10727 Rossmann-like domain 2 123 1.4E-45 T 14-10-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain A4R43_26775 073770ded1c3d2cdebc0c649e6d047e9 300 Gene3D G3DSA:1.10.1040.20 175 274 3.7E-18 T 14-10-2018 IPR037108 TM1727-like, C-terminal domain superfamily A4R43_26775 073770ded1c3d2cdebc0c649e6d047e9 300 Pfam PF10728 Domain of unknown function (DUF2520) 146 269 1.3E-42 T 14-10-2018 IPR018931 Domain of unknown function DUF2520 A4R43_37360 1888f6ad3a5ee5ff570ef54fbe0e6be0 453 Pfam PF00561 alpha/beta hydrolase fold 103 177 5.7E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_37360 1888f6ad3a5ee5ff570ef54fbe0e6be0 453 SUPERFAMILY SSF53474 34 383 3.46E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03745 2a179747c7880441aeae24a1f27187a4 474 Gene3D G3DSA:3.40.309.10 251 437 1.9E-160 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_03745 2a179747c7880441aeae24a1f27187a4 474 SUPERFAMILY SSF53720 2 471 3.01E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_03745 2a179747c7880441aeae24a1f27187a4 474 Pfam PF00171 Aldehyde dehydrogenase family 20 468 1.5E-151 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_03745 2a179747c7880441aeae24a1f27187a4 474 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_03745 2a179747c7880441aeae24a1f27187a4 474 Gene3D G3DSA:3.40.605.10 24 462 1.9E-160 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_03745 2a179747c7880441aeae24a1f27187a4 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_28330 c47f007b76b9a8129e02f1ee5c9dffe4 168 Gene3D G3DSA:3.10.450.50 1 128 4.7E-28 T 14-10-2018 A4R43_28330 c47f007b76b9a8129e02f1ee5c9dffe4 168 SUPERFAMILY SSF54427 4 107 1.17E-13 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_28330 c47f007b76b9a8129e02f1ee5c9dffe4 168 Pfam PF12680 SnoaL-like domain 6 100 2.2E-6 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_36970 984cac045102f97405dec613ecee7685 409 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 245 404 8.7E-45 T 14-10-2018 IPR000160 GGDEF domain A4R43_36970 984cac045102f97405dec613ecee7685 409 SUPERFAMILY SSF55073 253 402 4.71E-44 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_36970 984cac045102f97405dec613ecee7685 409 Gene3D G3DSA:3.30.70.270 237 404 2.0E-51 T 14-10-2018 A4R43_36970 984cac045102f97405dec613ecee7685 409 SMART SM00267 236 404 2.0E-57 T 14-10-2018 IPR000160 GGDEF domain A4R43_36970 984cac045102f97405dec613ecee7685 409 Pfam PF00990 Diguanylate cyclase, GGDEF domain 247 400 1.3E-41 T 14-10-2018 IPR000160 GGDEF domain A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 Pfam PF03466 LysR substrate binding domain 105 286 6.7E-12 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 SUPERFAMILY SSF53850 106 286 1.14E-12 T 14-10-2018 A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 SUPERFAMILY SSF46785 2 80 1.15E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 Gene3D G3DSA:3.40.190.10 114 289 4.6E-12 T 14-10-2018 A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 Gene3D G3DSA:1.10.10.10 4 85 3.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 Gene3D G3DSA:3.40.190.10 164 268 4.6E-12 T 14-10-2018 A4R43_14865 a7dda2d6a0a43937b08d84b9014d01f0 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.0E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17070 2d9a2ebff7bfb4549696d61da6f974e0 316 Gene3D G3DSA:1.10.600.10 9 291 6.7E-82 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_17070 2d9a2ebff7bfb4549696d61da6f974e0 316 Pfam PF00494 Squalene/phytoene synthase 28 284 2.8E-61 T 14-10-2018 A4R43_17070 2d9a2ebff7bfb4549696d61da6f974e0 316 SUPERFAMILY SSF48576 18 296 1.35E-71 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_17070 2d9a2ebff7bfb4549696d61da6f974e0 316 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 167 192 - T 14-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A4R43_31645 816b2732979bd9e9823a7e5aad93b1b6 214 Pfam PF07510 Protein of unknown function (DUF1524) 109 208 1.7E-9 T 14-10-2018 IPR011089 Domain of unknown function DUF1524 A4R43_31620 64d0bb8979ffa1ffbc6543f5fd008e60 343 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 6.3E-73 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_31620 64d0bb8979ffa1ffbc6543f5fd008e60 343 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 340 1.9E-79 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_31620 64d0bb8979ffa1ffbc6543f5fd008e60 343 Gene3D G3DSA:3.20.20.70 1 343 2.9E-128 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_31620 64d0bb8979ffa1ffbc6543f5fd008e60 343 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_31620 64d0bb8979ffa1ffbc6543f5fd008e60 343 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_31620 64d0bb8979ffa1ffbc6543f5fd008e60 343 PIRSF PIRSF001359 6 341 8.2E-64 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_31620 64d0bb8979ffa1ffbc6543f5fd008e60 343 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 339 4.8E-140 T 14-10-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A4R43_31620 64d0bb8979ffa1ffbc6543f5fd008e60 343 SUPERFAMILY SSF51569 4 340 4.4E-97 T 14-10-2018 A4R43_23840 70bb7ebf2845cc243481f0e6a38e4c7f 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 337 2.3E-45 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_23840 70bb7ebf2845cc243481f0e6a38e4c7f 440 SUPERFAMILY SSF51905 3 348 4.32E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_23840 70bb7ebf2845cc243481f0e6a38e4c7f 440 Gene3D G3DSA:3.50.50.100 1 408 2.3E-114 T 14-10-2018 A4R43_23840 70bb7ebf2845cc243481f0e6a38e4c7f 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 4.8E-9 T 14-10-2018 A4R43_23840 70bb7ebf2845cc243481f0e6a38e4c7f 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.8E-9 T 14-10-2018 A4R43_23840 70bb7ebf2845cc243481f0e6a38e4c7f 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 4.8E-9 T 14-10-2018 A4R43_11630 9b50127fa302fd1fcf0f3fcbcf3a669d 299 Pfam PF00005 ABC transporter 18 156 1.1E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_11630 9b50127fa302fd1fcf0f3fcbcf3a669d 299 SMART SM00382 26 204 1.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_11630 9b50127fa302fd1fcf0f3fcbcf3a669d 299 SUPERFAMILY SSF52540 2 219 1.9E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_11630 9b50127fa302fd1fcf0f3fcbcf3a669d 299 Gene3D G3DSA:3.40.50.300 1 229 1.2E-55 T 14-10-2018 A4R43_11630 9b50127fa302fd1fcf0f3fcbcf3a669d 299 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_34445 e5724045d4e311bcb5cc4de7c38ab55c 791 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 290 3.2E-79 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A4R43_34445 e5724045d4e311bcb5cc4de7c38ab55c 791 SUPERFAMILY SSF52540 16 681 1.5E-175 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34445 e5724045d4e311bcb5cc4de7c38ab55c 791 Gene3D G3DSA:1.10.486.10 402 585 5.4E-123 T 14-10-2018 A4R43_34445 e5724045d4e311bcb5cc4de7c38ab55c 791 Gene3D G3DSA:1.10.10.160 121 200 3.2E-99 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily A4R43_34445 e5724045d4e311bcb5cc4de7c38ab55c 791 Gene3D G3DSA:3.40.50.300 299 672 5.4E-123 T 14-10-2018 A4R43_34445 e5724045d4e311bcb5cc4de7c38ab55c 791 Pfam PF13361 UvrD-like helicase C-terminal domain 296 652 4.5E-64 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4R43_34445 e5724045d4e311bcb5cc4de7c38ab55c 791 Gene3D G3DSA:3.40.50.300 20 291 3.2E-99 T 14-10-2018 A4R43_34445 e5724045d4e311bcb5cc4de7c38ab55c 791 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 16 783 2.5E-289 T 14-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 SUPERFAMILY SSF52540 257 474 1.64E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 Gene3D G3DSA:1.25.40.10 101 262 1.8E-49 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 96 2.5E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 SMART SM01043 103 248 5.5E-49 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 Gene3D G3DSA:3.40.50.300 263 411 1.2E-6 T 14-10-2018 A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 Gene3D G3DSA:1.10.10.10 1 98 5.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 SMART SM00382 288 422 2.6E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 Pfam PF13191 AAA ATPase domain 265 328 2.0E-12 T 14-10-2018 A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 Pfam PF03704 Bacterial transcriptional activator domain 103 248 2.3E-40 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 SUPERFAMILY SSF46894 5 96 2.3E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 SUPERFAMILY SSF48452 99 263 3.45E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_15280 cbf21f095ab98b7443b56af4d969b414 1006 SMART SM00862 16 96 1.0E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_16555 d8ddd0af7a962e90f966888df7e40854 268 Gene3D G3DSA:3.10.20.310 77 144 1.7E-8 T 14-10-2018 A4R43_16555 d8ddd0af7a962e90f966888df7e40854 268 Pfam PF08478 POTRA domain, FtsQ-type 78 145 2.6E-17 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type A4R43_16555 d8ddd0af7a962e90f966888df7e40854 268 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 50 268 17.147 T 14-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 A4R43_16555 d8ddd0af7a962e90f966888df7e40854 268 Pfam PF03799 Cell division protein FtsQ 153 252 1.2E-10 T 14-10-2018 IPR005548 Cell division protein FtsQ/DivIB A4R43_28185 bd32f4f521a23db55c62c70afba4e8a6 271 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 14-10-2018 A4R43_28185 bd32f4f521a23db55c62c70afba4e8a6 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 267 5.3E-51 T 14-10-2018 A4R43_28185 bd32f4f521a23db55c62c70afba4e8a6 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 240 2.9E-25 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A4R43_28185 bd32f4f521a23db55c62c70afba4e8a6 271 Gene3D G3DSA:3.30.1240.10 86 196 4.4E-59 T 14-10-2018 A4R43_28185 bd32f4f521a23db55c62c70afba4e8a6 271 Gene3D G3DSA:3.40.50.1000 6 268 4.4E-59 T 14-10-2018 IPR023214 HAD superfamily A4R43_28185 bd32f4f521a23db55c62c70afba4e8a6 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 267 1.1E-40 T 14-10-2018 IPR000150 Cof family GO:0016787 A4R43_28185 bd32f4f521a23db55c62c70afba4e8a6 271 SUPERFAMILY SSF56784 4 271 5.47E-58 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_18025 1d0a601cc279a9ea6ff50862b079e976 138 Pfam PF11253 Protein of unknown function (DUF3052) 13 136 4.4E-54 T 14-10-2018 IPR021412 Protein of unknown function DUF3052 A4R43_34165 b220fd0092ffc97c4cf1a79ecc8a7c09 484 Gene3D G3DSA:3.40.190.10 69 430 7.2E-68 T 14-10-2018 A4R43_34165 b220fd0092ffc97c4cf1a79ecc8a7c09 484 Gene3D G3DSA:3.40.190.10 173 470 7.2E-68 T 14-10-2018 A4R43_34165 b220fd0092ffc97c4cf1a79ecc8a7c09 484 SUPERFAMILY SSF53850 49 479 2.59E-57 T 14-10-2018 A4R43_34165 b220fd0092ffc97c4cf1a79ecc8a7c09 484 Pfam PF01547 Bacterial extracellular solute-binding protein 65 381 4.2E-25 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_31355 2a0b2af5c17b05cb2f83310dfb1e3609 765 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 392 403 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_31355 2a0b2af5c17b05cb2f83310dfb1e3609 765 SUPERFAMILY SSF46548 281 420 4.19E-21 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_31355 2a0b2af5c17b05cb2f83310dfb1e3609 765 Pfam PF13183 4Fe-4S dicluster domain 296 406 1.4E-13 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_31355 2a0b2af5c17b05cb2f83310dfb1e3609 765 Pfam PF02754 Cysteine-rich domain 604 690 1.3E-16 T 14-10-2018 IPR004017 Cysteine-rich domain A4R43_31355 2a0b2af5c17b05cb2f83310dfb1e3609 765 Pfam PF02754 Cysteine-rich domain 474 565 7.0E-14 T 14-10-2018 IPR004017 Cysteine-rich domain A4R43_12415 681bd5e0cff959a076def264bf1ea715 383 SUPERFAMILY SSF53756 13 154 3.03E-5 T 14-10-2018 A4R43_03960 9b457d8689c84dfc827652ef7a3a589e 188 SUPERFAMILY SSF46689 5 72 2.94E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_03960 9b457d8689c84dfc827652ef7a3a589e 188 SUPERFAMILY SSF48498 80 184 1.26E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_03960 9b457d8689c84dfc827652ef7a3a589e 188 Pfam PF16925 Bacterial transcriptional repressor C-terminal 90 179 1.0E-6 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4R43_03960 9b457d8689c84dfc827652ef7a3a589e 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03960 9b457d8689c84dfc827652ef7a3a589e 188 Gene3D G3DSA:1.10.357.10 3 187 7.0E-52 T 14-10-2018 A4R43_03960 9b457d8689c84dfc827652ef7a3a589e 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 6.7E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03960 9b457d8689c84dfc827652ef7a3a589e 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 6.7E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14685 ad26e46f035f07bf6a467f3eb854071b 320 Pfam PF12679 ABC-2 family transporter protein 62 318 2.5E-11 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A4R43_37865 e31397741e6b40e881939a73b8181e52 360 Gene3D G3DSA:1.10.3470.10 35 359 4.8E-82 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_37865 e31397741e6b40e881939a73b8181e52 360 Pfam PF01032 FecCD transport family 49 352 9.1E-77 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_37865 e31397741e6b40e881939a73b8181e52 360 SUPERFAMILY SSF81345 30 352 7.19E-66 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_15155 a8d384f0a0ca67c247cceaa1bb85081c 363 SUPERFAMILY SSF55874 244 362 1.58E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_15155 a8d384f0a0ca67c247cceaa1bb85081c 363 Pfam PF07730 Histidine kinase 171 236 3.9E-20 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_15155 a8d384f0a0ca67c247cceaa1bb85081c 363 Gene3D G3DSA:3.30.565.10 238 363 1.2E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_41660 f11fbc209281e91a03fff1bc7c37befe 405 Pfam PF00246 Zinc carboxypeptidase 24 184 4.6E-13 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_41660 f11fbc209281e91a03fff1bc7c37befe 405 SUPERFAMILY SSF53187 17 264 6.28E-25 T 14-10-2018 A4R43_41660 f11fbc209281e91a03fff1bc7c37befe 405 Gene3D G3DSA:3.40.630.10 12 209 4.8E-24 T 14-10-2018 A4R43_23100 63e90dfca01e52326ae9f98f47884f87 160 SUPERFAMILY SSF54637 14 146 3.45E-25 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_23100 63e90dfca01e52326ae9f98f47884f87 160 Gene3D G3DSA:3.10.129.10 4 147 5.3E-44 T 14-10-2018 A4R43_23100 63e90dfca01e52326ae9f98f47884f87 160 Pfam PF14539 Domain of unknown function (DUF4442) 11 144 1.5E-56 T 14-10-2018 IPR027961 Protein of unknown function DUF4442 A4R43_05440 50c88e70cad381e2c80f6193d4519de5 137 Gene3D G3DSA:3.30.565.10 10 134 3.7E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_05440 50c88e70cad381e2c80f6193d4519de5 137 SUPERFAMILY SSF55874 47 127 7.53E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_05440 50c88e70cad381e2c80f6193d4519de5 137 Pfam PF13581 Histidine kinase-like ATPase domain 19 125 1.3E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_20015 8300ba8b95942fdc45b147a407f2b2cf 193 Pfam PF07681 DoxX 37 122 1.9E-16 T 14-10-2018 IPR032808 DoxX family A4R43_15765 0723b4d194ff71cb79c798ab6f572acd 257 SUPERFAMILY SSF52540 4 232 2.66E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_15765 0723b4d194ff71cb79c798ab6f572acd 257 SMART SM00382 30 220 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_15765 0723b4d194ff71cb79c798ab6f572acd 257 Pfam PF00005 ABC transporter 21 172 7.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_15765 0723b4d194ff71cb79c798ab6f572acd 257 Gene3D G3DSA:3.40.50.300 3 244 7.2E-61 T 14-10-2018 A4R43_29795 afaa00c460b08d300f4c4e8c8de22b30 266 SUPERFAMILY SSF52096 3 254 4.54E-76 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_29795 afaa00c460b08d300f4c4e8c8de22b30 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 254 3.3E-48 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_29795 afaa00c460b08d300f4c4e8c8de22b30 266 Gene3D G3DSA:3.90.226.10 1 244 1.1E-77 T 14-10-2018 A4R43_29795 afaa00c460b08d300f4c4e8c8de22b30 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_36200 3e4eb6f7e338f5bb1219c551df5da4cd 468 Pfam PF00773 RNB domain 46 352 1.1E-47 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 A4R43_36200 3e4eb6f7e338f5bb1219c551df5da4cd 468 SMART SM00955 46 364 2.5E-67 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 A4R43_36200 3e4eb6f7e338f5bb1219c551df5da4cd 468 SUPERFAMILY SSF50249 10 407 2.28E-93 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_19705 66d9f1289785c5f2793577c7ea6a5cb9 297 SUPERFAMILY SSF52540 6 218 1.18E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_19705 66d9f1289785c5f2793577c7ea6a5cb9 297 Gene3D G3DSA:3.40.50.300 1 227 2.9E-53 T 14-10-2018 A4R43_19705 66d9f1289785c5f2793577c7ea6a5cb9 297 SMART SM00382 30 206 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_19705 66d9f1289785c5f2793577c7ea6a5cb9 297 Pfam PF00005 ABC transporter 22 159 1.1E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_36010 8e647d5506ffd051def7f2d9d356eb9c 279 Pfam PF06271 RDD family 18 148 2.5E-17 T 14-10-2018 IPR010432 RDD A4R43_11945 be064490080e89a12c5490142392920e 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 255 3.1E-29 T 14-10-2018 A4R43_11945 be064490080e89a12c5490142392920e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11945 be064490080e89a12c5490142392920e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11945 be064490080e89a12c5490142392920e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11945 be064490080e89a12c5490142392920e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11945 be064490080e89a12c5490142392920e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_11945 be064490080e89a12c5490142392920e 261 SUPERFAMILY SSF51735 5 255 4.27E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_11945 be064490080e89a12c5490142392920e 261 Gene3D G3DSA:3.40.50.720 1 260 1.1E-42 T 14-10-2018 A4R43_21500 d7034c5bc2880550169f481b3d13a948 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 50 4.4E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21500 d7034c5bc2880550169f481b3d13a948 186 SUPERFAMILY SSF46689 2 68 7.48E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21500 d7034c5bc2880550169f481b3d13a948 186 ProSitePatterns PS01081 TetR-type HTH domain signature. 16 46 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_21500 d7034c5bc2880550169f481b3d13a948 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 4 17 1.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21500 d7034c5bc2880550169f481b3d13a948 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 48 1.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21500 d7034c5bc2880550169f481b3d13a948 186 Gene3D G3DSA:1.10.357.10 1 186 9.0E-45 T 14-10-2018 A4R43_02915 0704bc9ec82a9ce944f58ad932d8bb08 193 Pfam PF03713 Domain of unknown function (DUF305) 44 191 1.1E-50 T 14-10-2018 IPR005183 Domain of unknown function DUF305 A4R43_02915 0704bc9ec82a9ce944f58ad932d8bb08 193 Gene3D G3DSA:1.20.1260.10 32 193 5.1E-55 T 14-10-2018 IPR012347 Ferritin-like A4R43_13525 59cb01d107f22c1a4c49e38a0be9a0dd 476 Gene3D G3DSA:3.40.309.10 253 442 1.4E-180 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_13525 59cb01d107f22c1a4c49e38a0be9a0dd 476 Gene3D G3DSA:3.40.605.10 7 470 1.4E-180 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_13525 59cb01d107f22c1a4c49e38a0be9a0dd 476 Pfam PF00171 Aldehyde dehydrogenase family 11 472 2.6E-168 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_13525 59cb01d107f22c1a4c49e38a0be9a0dd 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_13525 59cb01d107f22c1a4c49e38a0be9a0dd 476 SUPERFAMILY SSF53720 3 475 8.51E-171 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_18360 1f06e09b6a046086678674873199f6f5 203 Gene3D G3DSA:1.10.10.10 48 146 6.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18360 1f06e09b6a046086678674873199f6f5 203 Pfam PF03551 Transcriptional regulator PadR-like family 59 127 6.5E-20 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_18360 1f06e09b6a046086678674873199f6f5 203 SUPERFAMILY SSF46785 45 138 4.27E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38875 0c10fa6d041037f79445448e9a22ff29 165 Pfam PF17174 Domain of unknown function (DUF5130) 20 155 5.5E-36 T 14-10-2018 IPR033437 Protein of unknown function DUF5130 A4R43_38875 0c10fa6d041037f79445448e9a22ff29 165 Gene3D G3DSA:3.10.310.50 44 164 4.7E-7 T 14-10-2018 A4R43_34805 ae00fe12dd1e77565780ee14bdebddc2 168 Gene3D G3DSA:3.40.50.1820 1 123 1.0E-8 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_34805 ae00fe12dd1e77565780ee14bdebddc2 168 SUPERFAMILY SSF53474 1 104 3.19E-5 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41150 7b541a325bd5541e56b0f4b9a69f0a9b 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.434 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_41150 7b541a325bd5541e56b0f4b9a69f0a9b 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 8.4E-39 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_41150 7b541a325bd5541e56b0f4b9a69f0a9b 89 SUPERFAMILY SSF47060 3 89 1.21E-34 T 14-10-2018 IPR009068 S15/NS1, RNA-binding A4R43_41150 7b541a325bd5541e56b0f4b9a69f0a9b 89 Pfam PF00312 Ribosomal protein S15 8 88 4.1E-36 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_41150 7b541a325bd5541e56b0f4b9a69f0a9b 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_41150 7b541a325bd5541e56b0f4b9a69f0a9b 89 SMART SM01387 8 88 6.7E-50 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_41150 7b541a325bd5541e56b0f4b9a69f0a9b 89 Gene3D G3DSA:1.10.287.10 1 89 3.0E-33 T 14-10-2018 A4R43_41150 7b541a325bd5541e56b0f4b9a69f0a9b 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 6.0E-21 T 14-10-2018 A4R43_07155 c190a85288bbaff242cce459b14b459b 386 SUPERFAMILY SSF103473 8 378 1.12E-47 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_07155 c190a85288bbaff242cce459b14b459b 386 Pfam PF07690 Major Facilitator Superfamily 22 322 1.4E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_07155 c190a85288bbaff242cce459b14b459b 386 Gene3D G3DSA:1.20.1250.20 14 376 1.9E-39 T 14-10-2018 A4R43_35100 7539e5f08a24b3559b7ff7cccc7fc0f4 343 Gene3D G3DSA:3.40.50.2300 138 335 1.1E-60 T 14-10-2018 A4R43_35100 7539e5f08a24b3559b7ff7cccc7fc0f4 343 Gene3D G3DSA:3.40.50.2300 48 293 1.1E-60 T 14-10-2018 A4R43_35100 7539e5f08a24b3559b7ff7cccc7fc0f4 343 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 50 324 1.7E-37 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A4R43_35100 7539e5f08a24b3559b7ff7cccc7fc0f4 343 SUPERFAMILY SSF53822 39 249 3.7E-8 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 Pfam PF13177 DNA polymerase III, delta subunit 19 177 7.8E-39 T 14-10-2018 A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 SUPERFAMILY SSF48019 246 363 5.1E-21 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 Gene3D G3DSA:3.40.50.300 12 178 1.2E-92 T 14-10-2018 A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 Gene3D G3DSA:1.10.8.60 7 237 1.2E-92 T 14-10-2018 A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 SMART SM00382 36 180 4.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 235 364 7.1E-16 T 14-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 SUPERFAMILY SSF52540 31 221 6.49E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 Gene3D G3DSA:1.20.272.10 244 366 3.9E-5 T 14-10-2018 A4R43_27445 878148963b6b51d5e90d6a825a0be99f 760 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 4 362 3.6E-111 T 14-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 A4R43_07475 579c7e77e25486e8d821d9e7fd76ec4c 328 Gene3D G3DSA:3.90.25.10 190 311 3.3E-96 T 14-10-2018 A4R43_07475 579c7e77e25486e8d821d9e7fd76ec4c 328 SUPERFAMILY SSF51735 6 314 8.93E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07475 579c7e77e25486e8d821d9e7fd76ec4c 328 Gene3D G3DSA:3.40.50.720 8 298 3.3E-96 T 14-10-2018 A4R43_07475 579c7e77e25486e8d821d9e7fd76ec4c 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 244 1.6E-46 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_33440 518e305d6f992165dda430aab52c7575 198 SUPERFAMILY SSF46689 3 70 2.86E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_33440 518e305d6f992165dda430aab52c7575 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 8.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33440 518e305d6f992165dda430aab52c7575 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 8.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33440 518e305d6f992165dda430aab52c7575 198 Gene3D G3DSA:1.10.357.10 51 198 1.4E-14 T 14-10-2018 A4R43_33440 518e305d6f992165dda430aab52c7575 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 8.0E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_33440 518e305d6f992165dda430aab52c7575 198 SUPERFAMILY SSF48498 88 198 5.09E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_33440 518e305d6f992165dda430aab52c7575 198 Gene3D G3DSA:1.10.10.60 2 50 2.5E-17 T 14-10-2018 A4R43_03970 858aa6e7759445ef4020c9ff72c0ad81 241 SMART SM00020 38 235 7.7E-19 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_03970 858aa6e7759445ef4020c9ff72c0ad81 241 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 110 124 4.0E-6 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_03970 858aa6e7759445ef4020c9ff72c0ad81 241 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 63 78 4.0E-6 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_03970 858aa6e7759445ef4020c9ff72c0ad81 241 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 193 205 4.0E-6 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_03970 858aa6e7759445ef4020c9ff72c0ad81 241 Gene3D G3DSA:2.40.10.10 39 111 2.8E-11 T 14-10-2018 A4R43_03970 858aa6e7759445ef4020c9ff72c0ad81 241 Gene3D G3DSA:2.40.10.10 112 239 7.3E-17 T 14-10-2018 A4R43_03970 858aa6e7759445ef4020c9ff72c0ad81 241 Pfam PF00089 Trypsin 42 235 2.8E-29 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_03970 858aa6e7759445ef4020c9ff72c0ad81 241 SUPERFAMILY SSF50494 12 239 1.05E-37 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_40285 1d9f168ec7982a80932c3a18cdee9377 113 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 106 7.4E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_40285 1d9f168ec7982a80932c3a18cdee9377 113 SUPERFAMILY SSF54593 6 112 2.42E-14 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_40285 1d9f168ec7982a80932c3a18cdee9377 113 Gene3D G3DSA:3.10.180.10 3 110 9.9E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_20915 3067eb81df1c45f73605362d7ee09d67 366 Pfam PF01699 Sodium/calcium exchanger protein 33 186 2.0E-12 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A4R43_20915 3067eb81df1c45f73605362d7ee09d67 366 Pfam PF01699 Sodium/calcium exchanger protein 222 363 3.5E-13 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 TIGRFAM TIGR00498 lexA: repressor LexA 15 217 4.3E-61 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 SUPERFAMILY SSF51306 97 216 8.2E-34 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 Gene3D G3DSA:1.10.10.10 15 82 3.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 Pfam PF01726 LexA DNA binding domain 15 77 4.3E-20 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 173 185 9.9E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 134 144 9.9E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 145 156 9.9E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 SUPERFAMILY SSF46785 17 81 2.27E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 Pfam PF00717 Peptidase S24-like 137 201 1.5E-13 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 Hamap MF_00015 LexA repressor [lexA]. 16 218 30.09 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A4R43_09770 12ffb10c68cbe0331c84ca7801c0e9de 218 Gene3D G3DSA:2.10.109.10 103 218 9.4E-38 T 14-10-2018 A4R43_26755 96d41f15b6f0ed845a58f35083ccd84b 115 Pfam PF11774 Lsr2 1 113 3.2E-45 T 14-10-2018 IPR024412 Lsr2 A4R43_26755 96d41f15b6f0ed845a58f35083ccd84b 115 Gene3D G3DSA:3.30.60.230 1 60 5.4E-29 T 14-10-2018 A4R43_26755 96d41f15b6f0ed845a58f35083ccd84b 115 Gene3D G3DSA:1.20.890.50 81 115 2.9E-17 T 14-10-2018 A4R43_26755 96d41f15b6f0ed845a58f35083ccd84b 115 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 113 8.0E-25 T 14-10-2018 IPR024412 Lsr2 A4R43_04630 38aac22e870b8728911b00d830f8c66c 138 Pfam PF00355 Rieske [2Fe-2S] domain 50 125 6.8E-18 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4R43_04630 38aac22e870b8728911b00d830f8c66c 138 PRINTS PR00162 Rieske 2Fe-2S subunit signature 98 110 6.5E-9 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4R43_04630 38aac22e870b8728911b00d830f8c66c 138 PRINTS PR00162 Rieske 2Fe-2S subunit signature 111 123 6.5E-9 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4R43_04630 38aac22e870b8728911b00d830f8c66c 138 PRINTS PR00162 Rieske 2Fe-2S subunit signature 79 90 6.5E-9 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4R43_04630 38aac22e870b8728911b00d830f8c66c 138 Gene3D G3DSA:2.102.10.10 41 138 3.0E-27 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_04630 38aac22e870b8728911b00d830f8c66c 138 SUPERFAMILY SSF50022 46 136 2.88E-29 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_02175 6ae064f683890e0bc2bb8b30ba8dfe16 659 Pfam PF14518 Iron-containing redox enzyme 456 632 6.3E-19 T 14-10-2018 A4R43_02175 6ae064f683890e0bc2bb8b30ba8dfe16 659 SMART SM01236 485 594 1.2E-29 T 14-10-2018 A4R43_02175 6ae064f683890e0bc2bb8b30ba8dfe16 659 Gene3D G3DSA:1.20.910.10 466 638 5.4E-9 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_14825 c105e90d54e1661226680001c978b6ec 341 Pfam PF07676 WD40-like Beta Propeller Repeat 241 256 0.0079 T 14-10-2018 IPR011659 WD40-like Beta Propeller A4R43_14825 c105e90d54e1661226680001c978b6ec 341 SUPERFAMILY SSF82171 189 328 1.31E-12 T 14-10-2018 A4R43_14825 c105e90d54e1661226680001c978b6ec 341 Gene3D G3DSA:2.120.10.30 188 341 3.1E-13 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_18665 6ed4790b42099d9834da49f9644c82db 129 SUPERFAMILY SSF54593 3 117 6.08E-12 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_18665 6ed4790b42099d9834da49f9644c82db 129 Gene3D G3DSA:3.10.180.10 2 128 6.1E-29 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 Hamap MF_00104 Ribonuclease 3 [rnc]. 16 232 29.082 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 Gene3D G3DSA:1.10.1520.10 11 162 3.9E-43 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 Gene3D G3DSA:3.30.160.20 169 238 2.9E-20 T 14-10-2018 A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 Pfam PF00035 Double-stranded RNA binding motif 170 235 2.0E-14 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 Pfam PF14622 Ribonuclease-III-like 25 153 6.8E-33 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 SUPERFAMILY SSF69065 16 172 1.69E-42 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 SUPERFAMILY SSF54768 124 236 3.3E-24 T 14-10-2018 A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 SMART SM00535 27 163 2.1E-45 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 ProSitePatterns PS00517 Ribonuclease III family signature. 49 57 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 SMART SM00358 170 236 2.6E-21 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain A4R43_18760 3f6f5a586c48d545a831e879ae14c1ce 248 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 25 234 4.2E-67 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A4R43_16505 644a5abd2382cf2c1ff9b8f5457d52f1 235 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 15 232 6.8E-54 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase A4R43_16505 644a5abd2382cf2c1ff9b8f5457d52f1 235 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 8 231 4.7E-70 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase A4R43_16505 644a5abd2382cf2c1ff9b8f5457d52f1 235 Gene3D G3DSA:3.60.140.10 1 234 3.7E-75 T 14-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily A4R43_16505 644a5abd2382cf2c1ff9b8f5457d52f1 235 SUPERFAMILY SSF64438 3 232 6.04E-71 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A4R43_05220 e4a4bdbc24e4eff90a4f7e32f9584a12 532 SUPERFAMILY SSF52096 232 513 2.78E-77 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_05220 e4a4bdbc24e4eff90a4f7e32f9584a12 532 Pfam PF01039 Carboxyl transferase domain 48 519 2.7E-137 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_05220 e4a4bdbc24e4eff90a4f7e32f9584a12 532 Gene3D G3DSA:3.90.226.10 268 532 4.0E-88 T 14-10-2018 A4R43_05220 e4a4bdbc24e4eff90a4f7e32f9584a12 532 SUPERFAMILY SSF52096 22 267 1.61E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_05220 e4a4bdbc24e4eff90a4f7e32f9584a12 532 Gene3D G3DSA:3.90.226.10 1 267 2.0E-83 T 14-10-2018 A4R43_30965 715aa193d87ef376760d20d00346c2a5 394 Gene3D G3DSA:3.50.50.60 8 338 4.5E-59 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30965 715aa193d87ef376760d20d00346c2a5 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.2E-7 T 14-10-2018 A4R43_30965 715aa193d87ef376760d20d00346c2a5 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 1.2E-7 T 14-10-2018 A4R43_30965 715aa193d87ef376760d20d00346c2a5 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.2E-7 T 14-10-2018 A4R43_30965 715aa193d87ef376760d20d00346c2a5 394 ProSitePatterns PS00217 Sugar transport proteins signature 2. 294 319 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_30965 715aa193d87ef376760d20d00346c2a5 394 Pfam PF01494 FAD binding domain 5 161 1.9E-7 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_30965 715aa193d87ef376760d20d00346c2a5 394 SUPERFAMILY SSF51905 1 362 1.34E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_30965 715aa193d87ef376760d20d00346c2a5 394 Gene3D G3DSA:3.30.9.50 41 269 4.5E-59 T 14-10-2018 A4R43_28010 174b60d8b0ffea3a9752b1520199ccd5 97 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 84 7.4E-33 T 14-10-2018 IPR018735 Protein of unknown function DUF2277 A4R43_10140 59f8805007d637365c9c0077cacdfddb 523 SUPERFAMILY SSF53300 333 519 3.56E-18 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_10140 59f8805007d637365c9c0077cacdfddb 523 Pfam PF00092 von Willebrand factor type A domain 336 508 4.3E-8 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_10140 59f8805007d637365c9c0077cacdfddb 523 Gene3D G3DSA:3.40.50.410 334 520 8.0E-21 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_10140 59f8805007d637365c9c0077cacdfddb 523 Pfam PF13531 Bacterial extracellular solute-binding protein 32 285 8.0E-21 T 14-10-2018 A4R43_10140 59f8805007d637365c9c0077cacdfddb 523 SUPERFAMILY SSF53850 31 312 1.68E-11 T 14-10-2018 A4R43_10140 59f8805007d637365c9c0077cacdfddb 523 SMART SM00327 333 516 1.5E-9 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_12100 8525c4e3ddaa80ccb5388834f3c87c01 134 Pfam PF13564 DoxX-like family 20 116 1.5E-16 T 14-10-2018 IPR032808 DoxX family A4R43_11245 f3cc5355f8b820f396bc855e6984576f 157 SUPERFAMILY SSF103256 1 136 2.48E-46 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 A4R43_11245 f3cc5355f8b820f396bc855e6984576f 157 Gene3D G3DSA:3.10.690.10 1 140 9.8E-47 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 A4R43_11245 f3cc5355f8b820f396bc855e6984576f 157 Pfam PF02577 Bifunctional nuclease 6 127 1.7E-44 T 14-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 A4R43_11760 9e67299544b9a980720dc9f2ad31b314 65 Pfam PF04024 PspC domain 6 62 2.0E-20 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A4R43_07685 50f5b57eb1f37461318f08430d3d1114 332 Gene3D G3DSA:3.40.50.620 194 298 4.4E-7 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_07685 50f5b57eb1f37461318f08430d3d1114 332 Pfam PF02698 DUF218 domain 159 306 2.8E-32 T 14-10-2018 IPR003848 Domain of unknown function DUF218 A4R43_35955 4e71435e1b38169c96fd4cb24d8471d7 1058 Pfam PF13361 UvrD-like helicase C-terminal domain 313 697 3.7E-18 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4R43_35955 4e71435e1b38169c96fd4cb24d8471d7 1058 SUPERFAMILY SSF52540 15 716 3.17E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_35955 4e71435e1b38169c96fd4cb24d8471d7 1058 Gene3D G3DSA:1.10.10.160 120 227 3.8E-45 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily A4R43_35955 4e71435e1b38169c96fd4cb24d8471d7 1058 Gene3D G3DSA:3.40.50.300 328 711 8.2E-34 T 14-10-2018 A4R43_35955 4e71435e1b38169c96fd4cb24d8471d7 1058 Pfam PF12705 PD-(D/E)XK nuclease superfamily 799 1047 4.0E-39 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A4R43_35955 4e71435e1b38169c96fd4cb24d8471d7 1058 Gene3D G3DSA:1.10.486.10 422 597 8.2E-34 T 14-10-2018 A4R43_35955 4e71435e1b38169c96fd4cb24d8471d7 1058 Gene3D G3DSA:3.40.50.300 20 304 3.8E-45 T 14-10-2018 A4R43_35955 4e71435e1b38169c96fd4cb24d8471d7 1058 Pfam PF00580 UvrD/REP helicase N-terminal domain 29 307 1.7E-35 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A4R43_31000 e890f14837d2ae780274e55312223b71 204 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_31000 e890f14837d2ae780274e55312223b71 204 SUPERFAMILY SSF52540 10 200 2.84E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31000 e890f14837d2ae780274e55312223b71 204 Pfam PF00005 ABC transporter 20 155 2.4E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_31000 e890f14837d2ae780274e55312223b71 204 Gene3D G3DSA:3.40.50.300 2 203 1.7E-43 T 14-10-2018 A4R43_31000 e890f14837d2ae780274e55312223b71 204 SMART SM00382 27 202 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_18115 7feef480003f9c1f9f0b7c6c4143825b 460 SUPERFAMILY SSF52467 286 458 9.35E-73 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_18115 7feef480003f9c1f9f0b7c6c4143825b 460 PIRSF PIRSF000204 1 459 3.1E-187 T 14-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 A4R43_18115 7feef480003f9c1f9f0b7c6c4143825b 460 Gene3D G3DSA:3.40.50.1220 277 460 9.1E-84 T 14-10-2018 A4R43_18115 7feef480003f9c1f9f0b7c6c4143825b 460 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 455 2.1E-178 T 14-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 A4R43_25370 19b85fa263249c8988303ebc8228dfb9 346 SUPERFAMILY SSF51735 138 306 4.99E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_25370 19b85fa263249c8988303ebc8228dfb9 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4R43_25370 19b85fa263249c8988303ebc8228dfb9 346 Gene3D G3DSA:3.90.180.10 1 343 3.5E-85 T 14-10-2018 A4R43_25370 19b85fa263249c8988303ebc8228dfb9 346 SUPERFAMILY SSF50129 1 170 5.53E-45 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_25370 19b85fa263249c8988303ebc8228dfb9 346 SMART SM00829 10 342 1.1E-5 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_25370 19b85fa263249c8988303ebc8228dfb9 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 127 2.4E-27 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_25370 19b85fa263249c8988303ebc8228dfb9 346 Pfam PF00107 Zinc-binding dehydrogenase 178 303 3.8E-25 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_12960 0cb053a55195cf76a0c8c035a1f07b49 365 Gene3D G3DSA:3.40.50.2300 159 293 5.2E-58 T 14-10-2018 A4R43_12960 0cb053a55195cf76a0c8c035a1f07b49 365 Pfam PF13407 Periplasmic binding protein domain 56 306 4.5E-45 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_12960 0cb053a55195cf76a0c8c035a1f07b49 365 Gene3D G3DSA:3.40.50.2300 59 301 5.2E-58 T 14-10-2018 A4R43_12960 0cb053a55195cf76a0c8c035a1f07b49 365 SUPERFAMILY SSF53822 54 333 1.46E-49 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_00295 755170b3717447f4ae7912836f1d83d1 263 Gene3D G3DSA:1.10.10.10 16 90 5.8E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_00295 755170b3717447f4ae7912836f1d83d1 263 SUPERFAMILY SSF46785 19 89 5.35E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_00295 755170b3717447f4ae7912836f1d83d1 263 SMART SM00346 16 106 1.2E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_00295 755170b3717447f4ae7912836f1d83d1 263 Pfam PF09339 IclR helix-turn-helix domain 21 69 2.5E-9 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_00295 755170b3717447f4ae7912836f1d83d1 263 Pfam PF01614 Bacterial transcriptional regulator 134 257 1.1E-31 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_00295 755170b3717447f4ae7912836f1d83d1 263 SUPERFAMILY SSF55781 75 257 1.49E-50 T 14-10-2018 A4R43_00295 755170b3717447f4ae7912836f1d83d1 263 Gene3D G3DSA:3.30.450.40 91 260 1.9E-55 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_19090 b86807f583211431129fd194fb26b816 215 Pfam PF13460 NAD(P)H-binding 7 199 2.6E-19 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_19090 b86807f583211431129fd194fb26b816 215 SUPERFAMILY SSF51735 1 213 8.28E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_19090 b86807f583211431129fd194fb26b816 215 Gene3D G3DSA:3.40.50.720 1 213 7.7E-39 T 14-10-2018 A4R43_28710 eac696ea083699a803779abcd45e2bc0 456 SUPERFAMILY SSF53187 52 453 1.69E-56 T 14-10-2018 A4R43_28710 eac696ea083699a803779abcd45e2bc0 456 Gene3D G3DSA:3.50.30.30 114 237 1.0E-87 T 14-10-2018 A4R43_28710 eac696ea083699a803779abcd45e2bc0 456 Pfam PF02225 PA domain 137 222 4.3E-7 T 14-10-2018 IPR003137 PA domain A4R43_28710 eac696ea083699a803779abcd45e2bc0 456 Gene3D G3DSA:3.40.630.10 74 442 1.0E-87 T 14-10-2018 A4R43_28710 eac696ea083699a803779abcd45e2bc0 456 Pfam PF04389 Peptidase family M28 254 441 5.7E-34 T 14-10-2018 IPR007484 Peptidase M28 A4R43_28710 eac696ea083699a803779abcd45e2bc0 456 SUPERFAMILY SSF52025 131 187 3.53E-6 T 14-10-2018 A4R43_18160 7b6643133bb125653d8d55e5c7e14194 136 PIRSF PIRSF004681 1 136 1.3E-26 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 A4R43_18160 7b6643133bb125653d8d55e5c7e14194 136 Gene3D G3DSA:2.60.120.460 1 135 1.6E-28 T 14-10-2018 IPR035917 YjbQ-like superfamily A4R43_18160 7b6643133bb125653d8d55e5c7e14194 136 SUPERFAMILY SSF111038 2 133 3.66E-31 T 14-10-2018 IPR035917 YjbQ-like superfamily A4R43_18160 7b6643133bb125653d8d55e5c7e14194 136 Pfam PF01894 Uncharacterised protein family UPF0047 18 130 2.8E-22 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 A4R43_18160 7b6643133bb125653d8d55e5c7e14194 136 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 5 123 3.2E-20 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 A4R43_04680 40e65ffc7e65461e609d0cbbd2e96897 503 Gene3D G3DSA:2.115.10.20 47 169 1.8E-11 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_04680 40e65ffc7e65461e609d0cbbd2e96897 503 Gene3D G3DSA:2.115.10.20 170 264 8.6E-9 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_04680 40e65ffc7e65461e609d0cbbd2e96897 503 SUPERFAMILY SSF75005 136 249 9.85E-20 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_35425 81e6266e2935fc19923757630442bba0 361 Pfam PF13692 Glycosyl transferases group 1 201 325 4.1E-19 T 14-10-2018 A4R43_35425 81e6266e2935fc19923757630442bba0 361 Gene3D G3DSA:3.40.50.2000 177 339 4.8E-49 T 14-10-2018 A4R43_35425 81e6266e2935fc19923757630442bba0 361 SUPERFAMILY SSF53756 8 357 1.41E-55 T 14-10-2018 A4R43_35425 81e6266e2935fc19923757630442bba0 361 Gene3D G3DSA:3.40.50.2000 14 355 4.8E-49 T 14-10-2018 A4R43_35425 81e6266e2935fc19923757630442bba0 361 Pfam PF13439 Glycosyltransferase Family 4 21 180 3.9E-11 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_39035 847eb3860875b352a5b69cf44a6b9c14 593 Gene3D G3DSA:2.40.30.10 308 404 5.3E-18 T 14-10-2018 A4R43_39035 847eb3860875b352a5b69cf44a6b9c14 593 Pfam PF00487 Fatty acid desaturase 41 270 1.1E-22 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_39035 847eb3860875b352a5b69cf44a6b9c14 593 SUPERFAMILY SSF63380 305 410 2.33E-23 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_39035 847eb3860875b352a5b69cf44a6b9c14 593 Gene3D G3DSA:3.40.50.80 413 573 3.0E-19 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_39035 847eb3860875b352a5b69cf44a6b9c14 593 Pfam PF00175 Oxidoreductase NAD-binding domain 421 492 6.4E-7 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4R43_39035 847eb3860875b352a5b69cf44a6b9c14 593 Pfam PF00970 Oxidoreductase FAD-binding domain 312 406 6.2E-11 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4R43_39035 847eb3860875b352a5b69cf44a6b9c14 593 SUPERFAMILY SSF52343 397 567 2.36E-21 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 Gene3D G3DSA:3.30.420.40 264 346 3.8E-5 T 14-10-2018 A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 Pfam PF00480 ROK family 92 258 1.4E-32 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 Gene3D G3DSA:3.30.420.40 78 205 3.6E-28 T 14-10-2018 A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 Pfam PF12802 MarR family 12 63 8.7E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 Gene3D G3DSA:1.10.10.10 2 77 7.3E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 SUPERFAMILY SSF53067 83 343 4.31E-40 T 14-10-2018 A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 ProSitePatterns PS01125 ROK family signature. 210 237 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 SUPERFAMILY SSF46785 10 73 1.5E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_30805 a6f06a2fe8a4e6bc956ee50281ce042f 352 Gene3D G3DSA:3.30.420.40 206 263 1.0E-20 T 14-10-2018 A4R43_10920 56e5eae3dbc54f0794a8130dfc864af1 197 SUPERFAMILY SSF46689 11 65 9.75E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_10920 56e5eae3dbc54f0794a8130dfc864af1 197 Gene3D G3DSA:1.10.357.10 3 196 2.6E-8 T 14-10-2018 A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 Pfam PF13183 4Fe-4S dicluster domain 526 604 6.1E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 SUPERFAMILY SSF46548 511 609 1.83E-8 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 590 601 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 SUPERFAMILY SSF55103 250 490 3.76E-50 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 Pfam PF02913 FAD linked oxidases, C-terminal domain 247 486 1.1E-48 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 Pfam PF01565 FAD binding domain 39 174 1.2E-37 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 Pfam PF02754 Cysteine-rich domain 702 775 0.0064 T 14-10-2018 IPR004017 Cysteine-rich domain A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 SUPERFAMILY SSF56176 2 247 6.95E-55 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_37895 98ace8a629c4c6c1cecaa62d474095e1 926 Gene3D G3DSA:3.30.70.2740 370 448 1.3E-7 T 14-10-2018 A4R43_00365 540a203cb5f2d60bdacc821bb59bd6d6 198 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 191 6.9E-17 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_00365 540a203cb5f2d60bdacc821bb59bd6d6 198 SUPERFAMILY SSF109854 13 138 1.98E-14 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_00365 540a203cb5f2d60bdacc821bb59bd6d6 198 Gene3D G3DSA:1.20.120.450 5 136 2.8E-7 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_00365 540a203cb5f2d60bdacc821bb59bd6d6 198 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 13 191 2.0E-34 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 A4R43_00365 540a203cb5f2d60bdacc821bb59bd6d6 198 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 133 7.8E-10 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 521 6.7E-30 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 321 7.5E-29 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 SUPERFAMILY SSF52467 157 347 3.89E-40 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 5.8E-54 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 Gene3D G3DSA:3.40.50.970 1 177 6.9E-60 T 14-10-2018 A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 SUPERFAMILY SSF52518 2 186 1.09E-53 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 Gene3D G3DSA:3.40.50.1220 183 344 9.5E-41 T 14-10-2018 A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 SUPERFAMILY SSF52518 358 522 4.47E-42 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_27960 66792856dc7f6cf408ef3b10040c2b06 524 Gene3D G3DSA:3.40.50.970 357 524 1.6E-41 T 14-10-2018 A4R43_26215 4030a3edf7a7b3f97fe64bcbace82e5c 329 SUPERFAMILY SSF53067 8 117 3.13E-16 T 14-10-2018 A4R43_26215 4030a3edf7a7b3f97fe64bcbace82e5c 329 Gene3D G3DSA:3.30.420.40 9 121 8.5E-56 T 14-10-2018 A4R43_26215 4030a3edf7a7b3f97fe64bcbace82e5c 329 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 10 312 3.8E-25 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A4R43_26215 4030a3edf7a7b3f97fe64bcbace82e5c 329 Gene3D G3DSA:3.30.420.40 122 278 8.5E-56 T 14-10-2018 A4R43_26215 4030a3edf7a7b3f97fe64bcbace82e5c 329 SUPERFAMILY SSF53067 122 313 4.07E-29 T 14-10-2018 A4R43_10625 ccbc5e4e7eb28eab32922c5b11b82528 401 Gene3D G3DSA:3.20.20.140 57 357 1.1E-136 T 14-10-2018 A4R43_10625 ccbc5e4e7eb28eab32922c5b11b82528 401 SUPERFAMILY SSF51556 56 361 1.06E-85 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_10625 ccbc5e4e7eb28eab32922c5b11b82528 401 SUPERFAMILY SSF51338 4 399 3.11E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_10625 ccbc5e4e7eb28eab32922c5b11b82528 401 Pfam PF01979 Amidohydrolase family 52 385 1.2E-42 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_10625 ccbc5e4e7eb28eab32922c5b11b82528 401 Gene3D G3DSA:2.30.40.10 8 398 1.1E-136 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_11690 472d03600fc15d4427f241238729cb15 206 Gene3D G3DSA:3.40.50.150 20 186 9.0E-18 T 14-10-2018 A4R43_11690 472d03600fc15d4427f241238729cb15 206 SUPERFAMILY SSF53335 19 177 2.09E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_11690 472d03600fc15d4427f241238729cb15 206 Pfam PF13649 Methyltransferase domain 40 136 2.8E-10 T 14-10-2018 A4R43_09440 0006e7422d5a3dbe4b9597e84d4c809b 391 SUPERFAMILY SSF103473 15 388 8.5E-44 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_09440 0006e7422d5a3dbe4b9597e84d4c809b 391 Gene3D G3DSA:1.20.1250.20 204 390 1.3E-22 T 14-10-2018 A4R43_09440 0006e7422d5a3dbe4b9597e84d4c809b 391 Gene3D G3DSA:1.20.1250.20 1 185 4.3E-18 T 14-10-2018 A4R43_09440 0006e7422d5a3dbe4b9597e84d4c809b 391 ProSitePatterns PS00216 Sugar transport proteins signature 1. 266 283 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_09440 0006e7422d5a3dbe4b9597e84d4c809b 391 Pfam PF07690 Major Facilitator Superfamily 252 386 5.7E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_09440 0006e7422d5a3dbe4b9597e84d4c809b 391 Pfam PF07690 Major Facilitator Superfamily 3 243 1.6E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_16800 8cd802a4dc76a2e3c5a56ab78bfae657 676 Pfam PF14082 Domain of unknown function (DUF4263) 489 634 1.9E-12 T 14-10-2018 IPR025359 Protein of unknown function DUF4263 A4R43_40360 db1bbe73ecdc2c113b3805091b2563ff 132 SUPERFAMILY SSF48619 44 131 5.11E-15 T 14-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A4R43_40360 db1bbe73ecdc2c113b3805091b2563ff 132 Gene3D G3DSA:1.20.90.10 28 132 7.6E-9 T 14-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A4R43_33125 c658a78c799ed347dfef742dd89ec060 287 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 35 183 1.2E-33 T 14-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33125 c658a78c799ed347dfef742dd89ec060 287 Gene3D G3DSA:1.20.120.1200 22 186 2.2E-43 T 14-10-2018 A4R43_21145 ff734da64d0c7157bfd011b685b369fe 193 Pfam PF00583 Acetyltransferase (GNAT) family 111 171 2.3E-7 T 14-10-2018 IPR000182 GNAT domain A4R43_21145 ff734da64d0c7157bfd011b685b369fe 193 SUPERFAMILY SSF55729 1 189 3.78E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_21145 ff734da64d0c7157bfd011b685b369fe 193 Gene3D G3DSA:3.40.630.30 2 193 3.4E-46 T 14-10-2018 A4R43_22520 232d741bf2cee61bf66590c6fc826294 349 SUPERFAMILY SSF51430 8 321 1.7E-97 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_22520 232d741bf2cee61bf66590c6fc826294 349 Gene3D G3DSA:3.20.20.100 7 345 8.6E-118 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_22520 232d741bf2cee61bf66590c6fc826294 349 PRINTS PR00069 Aldo-keto reductase signature 255 279 2.9E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_22520 232d741bf2cee61bf66590c6fc826294 349 PRINTS PR00069 Aldo-keto reductase signature 113 131 2.9E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_22520 232d741bf2cee61bf66590c6fc826294 349 Pfam PF00248 Aldo/keto reductase family 20 321 6.2E-75 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_11080 0ebe685ae5ec86bfa03fcd0db49f5df6 327 SMART SM00327 88 291 6.6E-21 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_11080 0ebe685ae5ec86bfa03fcd0db49f5df6 327 Pfam PF13519 von Willebrand factor type A domain 91 203 5.5E-17 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_11080 0ebe685ae5ec86bfa03fcd0db49f5df6 327 Gene3D G3DSA:3.40.50.410 90 289 1.0E-42 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_11080 0ebe685ae5ec86bfa03fcd0db49f5df6 327 SUPERFAMILY SSF53300 85 289 2.09E-28 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_11080 0ebe685ae5ec86bfa03fcd0db49f5df6 327 Pfam PF07584 Aerotolerance regulator N-terminal 5 78 2.2E-10 T 14-10-2018 IPR024163 Aerotolerance regulator, N-terminal A4R43_18355 60723dcc2bc9b150a0568b5e97581bba 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 366 1.6E-98 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 A4R43_18355 60723dcc2bc9b150a0568b5e97581bba 368 Gene3D G3DSA:1.10.150.530 18 76 5.0E-10 T 14-10-2018 A4R43_18355 60723dcc2bc9b150a0568b5e97581bba 368 SUPERFAMILY SSF102114 111 340 6.54E-19 T 14-10-2018 A4R43_18355 60723dcc2bc9b150a0568b5e97581bba 368 PIRSF PIRSF006004 12 368 1.8E-120 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 A4R43_18355 60723dcc2bc9b150a0568b5e97581bba 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 368 66.546 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 A4R43_18355 60723dcc2bc9b150a0568b5e97581bba 368 Gene3D G3DSA:3.20.20.70 82 355 1.7E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_18355 60723dcc2bc9b150a0568b5e97581bba 368 Pfam PF04055 Radical SAM superfamily 122 295 2.3E-23 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4R43_32160 4bf58a4abec9a28c5e960f156279ba3c 667 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 16 191 1.3E-21 T 14-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal A4R43_32160 4bf58a4abec9a28c5e960f156279ba3c 667 Gene3D G3DSA:1.50.10.10 236 610 5.7E-35 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4R43_32160 4bf58a4abec9a28c5e960f156279ba3c 667 SUPERFAMILY SSF48208 211 653 1.28E-62 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_21575 45d86bb531a800159211348c50c390f2 440 Pfam PF00266 Aminotransferase class-V 31 404 9.0E-67 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_21575 45d86bb531a800159211348c50c390f2 440 SUPERFAMILY SSF53383 27 412 5.5E-73 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_21575 45d86bb531a800159211348c50c390f2 440 Gene3D G3DSA:3.90.1150.10 27 405 3.9E-90 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_21575 45d86bb531a800159211348c50c390f2 440 Gene3D G3DSA:3.40.640.10 47 300 3.9E-90 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_09140 59863ddff5b574145e64452497cbd1f2 291 SUPERFAMILY SSF53697 4 288 3.56E-40 T 14-10-2018 A4R43_09140 59863ddff5b574145e64452497cbd1f2 291 Gene3D G3DSA:3.40.50.10490 5 152 4.1E-21 T 14-10-2018 A4R43_09140 59863ddff5b574145e64452497cbd1f2 291 Gene3D G3DSA:3.40.50.10490 246 290 8.4E-6 T 14-10-2018 A4R43_09140 59863ddff5b574145e64452497cbd1f2 291 Gene3D G3DSA:3.40.50.10490 153 243 1.1E-14 T 14-10-2018 A4R43_29990 6f1858176bc830b8b88e80f9fc96234b 395 PIRSF PIRSF000429 9 383 2.4E-23 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_29990 6f1858176bc830b8b88e80f9fc96234b 395 SUPERFAMILY SSF53901 241 386 5.12E-22 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_29990 6f1858176bc830b8b88e80f9fc96234b 395 SUPERFAMILY SSF53901 21 238 1.13E-22 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_29990 6f1858176bc830b8b88e80f9fc96234b 395 Gene3D G3DSA:3.40.47.10 4 393 2.7E-99 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_11370 38e449d092c3e844b78dde7f321f179f 670 Gene3D G3DSA:2.60.40.2300 543 670 7.3E-44 T 14-10-2018 IPR038445 Neutral ceramidase, C-terminal domain superfamily KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119 A4R43_11370 38e449d092c3e844b78dde7f321f179f 670 Pfam PF17048 Neutral/alkaline non-lysosomal ceramidase, C-terminal 510 669 4.4E-55 T 14-10-2018 IPR031331 Neutral/alkaline non-lysosomal ceramidase, C-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119 A4R43_11370 38e449d092c3e844b78dde7f321f179f 670 Pfam PF04734 Neutral/alkaline non-lysosomal ceramidase, N-terminal 33 508 3.2E-176 T 14-10-2018 IPR031329 Neutral/alkaline non-lysosomal ceramidase, N-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119|Reactome: R-HSA-1660662 A4R43_16705 7451a38dc797aed6c51e4c426ae78d5d 285 SUPERFAMILY SSF51261 65 149 4.29E-30 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_16705 7451a38dc797aed6c51e4c426ae78d5d 285 Pfam PF01551 Peptidase family M23 57 149 3.0E-24 T 14-10-2018 IPR016047 Peptidase M23 A4R43_16705 7451a38dc797aed6c51e4c426ae78d5d 285 Gene3D G3DSA:2.70.70.10 29 173 2.6E-31 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_03925 904fb059846660baa37d36a323157b4b 236 SMART SM00382 32 201 2.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03925 904fb059846660baa37d36a323157b4b 236 Pfam PF00005 ABC transporter 23 162 1.5E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_03925 904fb059846660baa37d36a323157b4b 236 Gene3D G3DSA:3.40.50.300 1 232 5.1E-58 T 14-10-2018 A4R43_03925 904fb059846660baa37d36a323157b4b 236 SUPERFAMILY SSF52540 6 225 2.88E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21505 13a6a5540cb6065dbc0850599a9ca93b 730 Pfam PF03176 MMPL family 395 709 4.7E-30 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_21505 13a6a5540cb6065dbc0850599a9ca93b 730 Pfam PF03176 MMPL family 49 365 3.5E-43 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_21505 13a6a5540cb6065dbc0850599a9ca93b 730 SUPERFAMILY SSF82866 120 341 6.15E-30 T 14-10-2018 A4R43_21505 13a6a5540cb6065dbc0850599a9ca93b 730 Gene3D G3DSA:1.20.1640.10 146 352 1.6E-6 T 14-10-2018 A4R43_21505 13a6a5540cb6065dbc0850599a9ca93b 730 SUPERFAMILY SSF82866 495 700 3.14E-25 T 14-10-2018 A4R43_08215 dbd7510a20a221c29b18a471e3abeccb 292 SUPERFAMILY SSF53850 90 277 2.35E-23 T 14-10-2018 A4R43_08215 dbd7510a20a221c29b18a471e3abeccb 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.8E-13 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_08215 dbd7510a20a221c29b18a471e3abeccb 292 SUPERFAMILY SSF46785 3 110 1.13E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08215 dbd7510a20a221c29b18a471e3abeccb 292 Gene3D G3DSA:3.40.190.290 175 280 7.5E-10 T 14-10-2018 A4R43_08215 dbd7510a20a221c29b18a471e3abeccb 292 Pfam PF03466 LysR substrate binding domain 89 272 4.8E-21 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_08215 dbd7510a20a221c29b18a471e3abeccb 292 Gene3D G3DSA:3.40.190.10 82 174 1.3E-12 T 14-10-2018 A4R43_08215 dbd7510a20a221c29b18a471e3abeccb 292 Gene3D G3DSA:1.10.10.10 2 81 7.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_24685 8d2b2b0121b5c890dfcf19edc7686976 697 TIGRFAM TIGR04364 methyltran_FxLD: methyltransferase, FxLD system 294 696 1.1E-134 T 14-10-2018 IPR027573 Methyltransferase, FxLD system A4R43_24685 8d2b2b0121b5c890dfcf19edc7686976 697 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 9 258 5.5E-49 T 14-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain A4R43_24685 8d2b2b0121b5c890dfcf19edc7686976 697 SUPERFAMILY SSF53335 295 495 2.17E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_24685 8d2b2b0121b5c890dfcf19edc7686976 697 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 299 506 2.2E-44 T 14-10-2018 A4R43_24685 8d2b2b0121b5c890dfcf19edc7686976 697 Gene3D G3DSA:3.40.50.150 282 515 2.9E-68 T 14-10-2018 A4R43_24685 8d2b2b0121b5c890dfcf19edc7686976 697 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 6 258 4.3E-32 T 14-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain A4R43_14395 dbc2fabe2c8c147fb1f9639cfaeaafe3 253 Gene3D G3DSA:3.30.450.40 74 249 1.7E-56 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_14395 dbc2fabe2c8c147fb1f9639cfaeaafe3 253 Pfam PF09339 IclR helix-turn-helix domain 4 53 6.9E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_14395 dbc2fabe2c8c147fb1f9639cfaeaafe3 253 Gene3D G3DSA:1.10.10.10 2 73 2.3E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14395 dbc2fabe2c8c147fb1f9639cfaeaafe3 253 SUPERFAMILY SSF46785 3 72 8.63E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14395 dbc2fabe2c8c147fb1f9639cfaeaafe3 253 SUPERFAMILY SSF55781 57 245 7.19E-50 T 14-10-2018 A4R43_14395 dbc2fabe2c8c147fb1f9639cfaeaafe3 253 Pfam PF01614 Bacterial transcriptional regulator 117 239 5.4E-32 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_14395 dbc2fabe2c8c147fb1f9639cfaeaafe3 253 SMART SM00346 2 89 1.4E-20 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_01755 f9f09f63c190b0e7e139925d3222a831 293 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 217 231 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4R43_01755 f9f09f63c190b0e7e139925d3222a831 293 Pfam PF01636 Phosphotransferase enzyme family 24 249 2.0E-35 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_01755 f9f09f63c190b0e7e139925d3222a831 293 Gene3D G3DSA:3.30.200.20 6 94 1.1E-11 T 14-10-2018 A4R43_01755 f9f09f63c190b0e7e139925d3222a831 293 SUPERFAMILY SSF56112 11 256 4.26E-45 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_01755 f9f09f63c190b0e7e139925d3222a831 293 Gene3D G3DSA:3.90.1200.10 103 269 3.7E-22 T 14-10-2018 A4R43_33515 16965f7bfa59ecdf1ad3ff663f88adf6 136 Gene3D G3DSA:3.10.129.10 1 135 3.1E-43 T 14-10-2018 A4R43_33515 16965f7bfa59ecdf1ad3ff663f88adf6 136 SUPERFAMILY SSF54637 4 126 1.17E-25 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_33515 16965f7bfa59ecdf1ad3ff663f88adf6 136 Pfam PF01575 MaoC like domain 13 118 4.9E-24 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_11565 f5faefdf08e652eeb1f3dd2ae7bc59af 340 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 98 112 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4R43_11565 f5faefdf08e652eeb1f3dd2ae7bc59af 340 Pfam PF00348 Polyprenyl synthetase 60 289 7.0E-56 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A4R43_11565 f5faefdf08e652eeb1f3dd2ae7bc59af 340 Gene3D G3DSA:1.10.600.10 12 340 1.0E-105 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_11565 f5faefdf08e652eeb1f3dd2ae7bc59af 340 SUPERFAMILY SSF48576 24 339 6.19E-74 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_11035 68f808fbedaaafdbe55dc3858fcbf378 238 Pfam PF12867 DinB superfamily 99 224 2.7E-10 T 14-10-2018 IPR024775 DinB-like domain A4R43_11035 68f808fbedaaafdbe55dc3858fcbf378 238 SUPERFAMILY SSF109854 100 222 7.17E-10 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_11035 68f808fbedaaafdbe55dc3858fcbf378 238 Gene3D G3DSA:1.20.120.450 97 224 2.5E-7 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_11035 68f808fbedaaafdbe55dc3858fcbf378 238 Pfam PF00805 Pentapeptide repeats (8 copies) 8 32 9.2E-4 T 14-10-2018 IPR001646 Pentapeptide repeat A4R43_40995 e82dabf64536a4fa071d9cdf67147740 480 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 60 219 2.3E-10 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4R43_06580 d49c20105ff72482985d50d8117a5c74 316 Pfam PF07070 SpoOM protein 2 217 1.5E-80 T 14-10-2018 IPR009776 Sporulation stage 0, protein M A4R43_32460 c39a6445fa1d39c52a17a23c4a8b57de 479 Pfam PF00171 Aldehyde dehydrogenase family 12 473 6.7E-162 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_32460 c39a6445fa1d39c52a17a23c4a8b57de 479 Gene3D G3DSA:3.40.309.10 253 444 1.4E-171 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_32460 c39a6445fa1d39c52a17a23c4a8b57de 479 SUPERFAMILY SSF53720 3 477 3.01E-160 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_32460 c39a6445fa1d39c52a17a23c4a8b57de 479 Gene3D G3DSA:3.40.605.10 6 472 1.4E-171 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_32460 c39a6445fa1d39c52a17a23c4a8b57de 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_23515 a2ea9b6360fabbf0cd3c59edc72843ed 296 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 51 66 1.4E-9 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_23515 a2ea9b6360fabbf0cd3c59edc72843ed 296 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 106 120 1.4E-9 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_23515 a2ea9b6360fabbf0cd3c59edc72843ed 296 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 191 203 1.4E-9 T 14-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4R43_23515 a2ea9b6360fabbf0cd3c59edc72843ed 296 SMART SM00020 24 243 3.8E-44 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_23515 a2ea9b6360fabbf0cd3c59edc72843ed 296 Gene3D G3DSA:2.40.10.10 18 248 7.8E-46 T 14-10-2018 A4R43_23515 a2ea9b6360fabbf0cd3c59edc72843ed 296 Pfam PF00089 Trypsin 27 243 4.8E-41 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_23515 a2ea9b6360fabbf0cd3c59edc72843ed 296 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 61 66 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4R43_23515 a2ea9b6360fabbf0cd3c59edc72843ed 296 SUPERFAMILY SSF50494 7 247 3.35E-52 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_41515 0da00ecd81e5db7fcb834792d320ef00 1011 Gene3D G3DSA:2.60.120.940 696 880 1.6E-22 T 14-10-2018 A4R43_41515 0da00ecd81e5db7fcb834792d320ef00 1011 Gene3D G3DSA:2.60.120.610 1 166 3.7E-36 T 14-10-2018 IPR027451 Arabinofuranosyltransferase, domain 1 A4R43_41515 0da00ecd81e5db7fcb834792d320ef00 1011 Pfam PF14896 EmbC C-terminal domain 751 999 1.0E-50 T 14-10-2018 IPR032731 Arabinosyltransferase, C-terminal A4R43_41515 0da00ecd81e5db7fcb834792d320ef00 1011 Pfam PF14896 EmbC C-terminal domain 657 718 1.1E-8 T 14-10-2018 IPR032731 Arabinosyltransferase, C-terminal A4R43_41515 0da00ecd81e5db7fcb834792d320ef00 1011 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 1 616 3.9E-224 T 14-10-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 A4R43_26235 78492cde61b8adda1e7bf29020de945d 419 SUPERFAMILY SSF140459 28 122 1.23E-5 T 14-10-2018 A4R43_26235 78492cde61b8adda1e7bf29020de945d 419 Gene3D G3DSA:1.20.1260.20 27 131 2.3E-5 T 14-10-2018 IPR038332 PPE superfamily A4R43_09725 299dc04b07be5948a91e67dad8cd6514 306 Gene3D G3DSA:3.40.50.720 130 255 7.7E-89 T 14-10-2018 A4R43_09725 299dc04b07be5948a91e67dad8cd6514 306 SUPERFAMILY SSF51735 119 240 2.9E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09725 299dc04b07be5948a91e67dad8cd6514 306 Gene3D G3DSA:3.90.180.10 9 303 7.7E-89 T 14-10-2018 A4R43_09725 299dc04b07be5948a91e67dad8cd6514 306 Pfam PF13602 Zinc-binding dehydrogenase 189 304 1.1E-17 T 14-10-2018 A4R43_09725 299dc04b07be5948a91e67dad8cd6514 306 SMART SM00829 10 304 7.0E-33 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4R43_09725 299dc04b07be5948a91e67dad8cd6514 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 5.7E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_09725 299dc04b07be5948a91e67dad8cd6514 306 SUPERFAMILY SSF50129 1 151 1.98E-37 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_12130 eb6a9c4d8034cc9b324dc7de21413d2d 222 Pfam PF13628 Domain of unknown function (DUF4142) 69 201 2.0E-19 T 14-10-2018 IPR025419 Domain of unknown function DUF4142 A4R43_12280 782d483c8d80394f14e5d3ecaec4f55c 126 SUPERFAMILY SSF82607 17 97 1.44E-10 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_12280 782d483c8d80394f14e5d3ecaec4f55c 126 Gene3D G3DSA:3.30.1310.10 20 92 2.2E-11 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_12280 782d483c8d80394f14e5d3ecaec4f55c 126 Pfam PF02575 YbaB/EbfC DNA-binding family 17 94 2.7E-13 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_14895 ca5f2dddebfecc78d90bc902f44fc2b8 393 Gene3D G3DSA:3.40.50.2300 57 366 3.4E-75 T 14-10-2018 A4R43_14895 ca5f2dddebfecc78d90bc902f44fc2b8 393 Pfam PF13458 Periplasmic binding protein 57 385 1.8E-39 T 14-10-2018 IPR028081 Leucine-binding protein domain A4R43_14895 ca5f2dddebfecc78d90bc902f44fc2b8 393 SUPERFAMILY SSF53822 57 387 1.48E-66 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_14895 ca5f2dddebfecc78d90bc902f44fc2b8 393 Gene3D G3DSA:3.40.50.2300 172 297 3.4E-75 T 14-10-2018 A4R43_09980 e49e31d5f1ae0cf93dd955b0a992a351 333 Pfam PF01384 Phosphate transporter family 22 321 8.2E-78 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A4R43_29655 52df7987e5f09da4325b075ae4674391 482 Gene3D G3DSA:3.40.50.300 227 450 1.8E-53 T 14-10-2018 A4R43_29655 52df7987e5f09da4325b075ae4674391 482 SUPERFAMILY SSF52540 108 408 5.93E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29655 52df7987e5f09da4325b075ae4674391 482 Pfam PF00437 Type II/IV secretion system protein 131 410 3.5E-44 T 14-10-2018 IPR001482 Type II/IV secretion system protein A4R43_29655 52df7987e5f09da4325b075ae4674391 482 Gene3D G3DSA:3.30.450.380 39 224 1.4E-17 T 14-10-2018 A4R43_17765 4c2902faa259fd91aa4ef3928ffa6c13 216 Pfam PF11241 Protein of unknown function (DUF3043) 36 214 6.4E-60 T 14-10-2018 IPR021403 Protein of unknown function DUF3043 A4R43_16785 9782aa6a4bd4a99b01efa64d19e11874 265 Pfam PF13460 NAD(P)H-binding 8 137 3.2E-18 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_16785 9782aa6a4bd4a99b01efa64d19e11874 265 SUPERFAMILY SSF51735 2 216 6.05E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_16785 9782aa6a4bd4a99b01efa64d19e11874 265 Gene3D G3DSA:3.40.50.720 4 258 2.5E-41 T 14-10-2018 A4R43_41465 bf1b477d6066cc775eaf6964c4e07a30 168 Gene3D G3DSA:1.10.10.10 25 164 8.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41465 bf1b477d6066cc775eaf6964c4e07a30 168 SMART SM00347 37 139 7.1E-4 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_41465 bf1b477d6066cc775eaf6964c4e07a30 168 SUPERFAMILY SSF46785 6 154 1.09E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_41465 bf1b477d6066cc775eaf6964c4e07a30 168 Pfam PF12802 MarR family 61 103 2.9E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_36645 ead93fcc54b31b2f3c5cea59f545f41d 225 Pfam PF02709 N-terminal domain of galactosyltransferase 140 176 2.3E-10 T 14-10-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 A4R43_36645 ead93fcc54b31b2f3c5cea59f545f41d 225 Gene3D G3DSA:3.90.550.10 1 221 1.2E-18 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_36645 ead93fcc54b31b2f3c5cea59f545f41d 225 SUPERFAMILY SSF53448 3 196 2.25E-21 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_08240 3c34808c1439839b85130823f99f485f 512 Gene3D G3DSA:1.20.1250.20 257 491 5.5E-17 T 14-10-2018 A4R43_08240 3c34808c1439839b85130823f99f485f 512 Gene3D G3DSA:1.20.1720.10 10 229 1.4E-44 T 14-10-2018 A4R43_08240 3c34808c1439839b85130823f99f485f 512 Pfam PF07690 Major Facilitator Superfamily 13 408 2.4E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_08240 3c34808c1439839b85130823f99f485f 512 SUPERFAMILY SSF103473 9 489 2.09E-63 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08240 3c34808c1439839b85130823f99f485f 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 1.9E-9 T 14-10-2018 A4R43_08240 3c34808c1439839b85130823f99f485f 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.9E-9 T 14-10-2018 A4R43_08240 3c34808c1439839b85130823f99f485f 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 1.9E-9 T 14-10-2018 A4R43_08240 3c34808c1439839b85130823f99f485f 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 1.9E-9 T 14-10-2018 A4R43_32835 da4f6e74a66d748c2c9e966e078181d7 349 Gene3D G3DSA:3.40.50.720 2 319 2.5E-40 T 14-10-2018 A4R43_32835 da4f6e74a66d748c2c9e966e078181d7 349 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 2.4E-21 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_32835 da4f6e74a66d748c2c9e966e078181d7 349 SUPERFAMILY SSF51735 1 317 3.86E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_27580 4bcb63e712d08c045041cef3decc596b 225 Pfam PF00072 Response regulator receiver domain 4 112 3.0E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27580 4bcb63e712d08c045041cef3decc596b 225 SUPERFAMILY SSF52172 3 126 6.83E-42 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_27580 4bcb63e712d08c045041cef3decc596b 225 SUPERFAMILY SSF46894 129 223 8.79E-29 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_27580 4bcb63e712d08c045041cef3decc596b 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 222 4.5E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_27580 4bcb63e712d08c045041cef3decc596b 225 Gene3D G3DSA:1.10.10.10 128 225 1.4E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27580 4bcb63e712d08c045041cef3decc596b 225 Gene3D G3DSA:3.40.50.2300 2 127 4.9E-39 T 14-10-2018 A4R43_27580 4bcb63e712d08c045041cef3decc596b 225 SMART SM00448 2 112 5.4E-45 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_27580 4bcb63e712d08c045041cef3decc596b 225 SMART SM00862 146 222 7.4E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 SUPERFAMILY SSF55874 290 414 3.8E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 PIRSF PIRSF037434 14 421 3.3E-71 T 14-10-2018 IPR017205 Signal transduction histidine kinase, ChrS A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 395 7.7E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 414 7.7E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 7.7E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 Gene3D G3DSA:3.30.565.10 283 415 2.4E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 414 3.1E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 SMART SM00387 320 417 5.1E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_35040 c50439c5dbd0d8bc9e9787283c925ffb 424 Pfam PF07730 Histidine kinase 216 281 6.2E-16 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_41555 62ec3c9280f29384b7c534f670f955f5 335 Pfam PF00155 Aminotransferase class I and II 17 327 1.2E-28 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_41555 62ec3c9280f29384b7c534f670f955f5 335 Gene3D G3DSA:3.40.640.10 28 239 8.2E-78 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_41555 62ec3c9280f29384b7c534f670f955f5 335 Gene3D G3DSA:3.90.1150.10 16 331 8.2E-78 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_41555 62ec3c9280f29384b7c534f670f955f5 335 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 191 204 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4R43_41555 62ec3c9280f29384b7c534f670f955f5 335 SUPERFAMILY SSF53383 13 333 2.81E-55 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_09540 b20ad8aee424391fc509d73220c8294a 314 SUPERFAMILY SSF161098 93 293 1.09E-15 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_09540 b20ad8aee424391fc509d73220c8294a 314 Gene3D G3DSA:1.10.3720.10 88 307 1.8E-19 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_09540 b20ad8aee424391fc509d73220c8294a 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 310 6.9E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_20505 5d07325b3da7ef175891e2bc521da991 254 Pfam PF00005 ABC transporter 22 177 8.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_20505 5d07325b3da7ef175891e2bc521da991 254 SUPERFAMILY SSF52540 5 232 5.83E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20505 5d07325b3da7ef175891e2bc521da991 254 Gene3D G3DSA:3.40.50.300 2 243 2.9E-53 T 14-10-2018 A4R43_20505 5d07325b3da7ef175891e2bc521da991 254 SMART SM00382 30 225 1.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_03455 c3e319c4578ab6716d06eb9284dc827d 388 SUPERFAMILY SSF53383 6 369 4.03E-104 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_03455 c3e319c4578ab6716d06eb9284dc827d 388 Gene3D G3DSA:3.90.1150.10 14 375 5.1E-125 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_03455 c3e319c4578ab6716d06eb9284dc827d 388 Pfam PF00266 Aminotransferase class-V 9 333 2.3E-33 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_03455 c3e319c4578ab6716d06eb9284dc827d 388 Gene3D G3DSA:3.40.640.10 19 265 5.1E-125 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_03455 c3e319c4578ab6716d06eb9284dc827d 388 PIRSF PIRSF000524 1 388 6.4E-129 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A4R43_10450 89ac48b06766f1447741266c041d00e9 139 Pfam PF14216 Domain of unknown function (DUF4326) 58 128 2.4E-14 T 14-10-2018 IPR025475 Protein of unknown function DUF4326) A4R43_10840 c468d2146d017e4dc477849a398dd2fc 304 Pfam PF12705 PD-(D/E)XK nuclease superfamily 25 277 1.8E-36 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A4R43_10840 c468d2146d017e4dc477849a398dd2fc 304 SUPERFAMILY SSF52980 45 213 2.95E-9 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4R43_10840 c468d2146d017e4dc477849a398dd2fc 304 Gene3D G3DSA:3.90.320.10 18 281 3.1E-8 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A4R43_02075 cb048b0b51c80d2e7f89349af1225ceb 356 SMART SM01329 2 347 2.4E-143 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_02075 cb048b0b51c80d2e7f89349af1225ceb 356 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 343 7.6E-91 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4R43_02075 cb048b0b51c80d2e7f89349af1225ceb 356 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 236 255 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4R43_02075 cb048b0b51c80d2e7f89349af1225ceb 356 SUPERFAMILY SSF53659 2 351 3.84E-102 T 14-10-2018 A4R43_02075 cb048b0b51c80d2e7f89349af1225ceb 356 Gene3D G3DSA:3.40.718.10 1 355 2.0E-117 T 14-10-2018 A4R43_22705 6056a2b2626493bf43269edd98380e50 563 Pfam PF02538 Hydantoinase B/oxoprolinase 4 511 1.2E-137 T 14-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 A4R43_33520 6f4dd359e4cb743f44db6150c87703ee 300 Gene3D G3DSA:3.40.50.1110 45 300 2.9E-78 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_33520 6f4dd359e4cb743f44db6150c87703ee 300 SUPERFAMILY SSF52266 46 299 7.33E-67 T 14-10-2018 A4R43_33520 6f4dd359e4cb743f44db6150c87703ee 300 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 51 290 2.0E-29 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_27215 81c252694a74c2782cdd0a05b72706f2 151 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 149 2.8E-33 T 14-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4R43_27215 81c252694a74c2782cdd0a05b72706f2 151 SUPERFAMILY SSF55298 1 150 8.95E-56 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_27215 81c252694a74c2782cdd0a05b72706f2 151 Gene3D G3DSA:3.30.1330.40 1 151 3.2E-60 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_05480 acc7daf89ae3af80b61c2d7c200df532 125 Pfam PF13466 STAS domain 23 99 3.1E-10 T 14-10-2018 IPR002645 STAS domain A4R43_05480 acc7daf89ae3af80b61c2d7c200df532 125 SUPERFAMILY SSF52091 15 114 1.43E-14 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_05480 acc7daf89ae3af80b61c2d7c200df532 125 Gene3D G3DSA:3.30.750.24 9 118 1.0E-19 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 Gene3D G3DSA:3.40.190.290 90 289 4.4E-48 T 14-10-2018 A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.5E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 SUPERFAMILY SSF46785 2 83 3.94E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 SUPERFAMILY SSF53850 88 289 1.18E-40 T 14-10-2018 A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 Gene3D G3DSA:1.10.10.10 1 85 1.4E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.5E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.5E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.5E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_15180 2a0b35bb6eface64d7d5346c7cb07575 291 Pfam PF03466 LysR substrate binding domain 88 288 1.0E-44 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_17515 2923c6f7a6e813a7308965a22cf547ab 100 SUPERFAMILY SSF140453 4 98 1.7E-8 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_17515 2923c6f7a6e813a7308965a22cf547ab 100 Gene3D G3DSA:1.10.287.1060 4 99 5.8E-12 T 14-10-2018 A4R43_06855 5f4dfc008de9b18ed93198bdb40c4a8b 264 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 69 150 7.0E-12 T 14-10-2018 IPR025847 MEDS domain A4R43_06855 5f4dfc008de9b18ed93198bdb40c4a8b 264 Gene3D G3DSA:3.30.750.24 167 251 6.2E-6 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_39425 5e3d66593748790deb1705d90d1fd372 196 SUPERFAMILY SSF53335 23 181 3.91E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_39425 5e3d66593748790deb1705d90d1fd372 196 Pfam PF08241 Methyltransferase domain 52 146 1.5E-19 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_39425 5e3d66593748790deb1705d90d1fd372 196 Gene3D G3DSA:3.40.50.150 4 194 2.0E-33 T 14-10-2018 A4R43_14570 7c0c0806b7690f9516d4767468144001 226 Gene3D G3DSA:3.40.50.1240 24 226 2.2E-44 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_14570 7c0c0806b7690f9516d4767468144001 226 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 26 221 2.1E-44 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_14570 7c0c0806b7690f9516d4767468144001 226 SUPERFAMILY SSF53254 26 224 9.72E-44 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_14570 7c0c0806b7690f9516d4767468144001 226 SMART SM00855 25 183 2.1E-11 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 Gene3D G3DSA:1.10.3860.10 2 427 1.1E-106 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 Pfam PF00375 Sodium:dicarboxylate symporter family 16 413 1.6E-94 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 SUPERFAMILY SSF118215 16 413 2.75E-87 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 PRINTS PR00173 Glutamate-aspartate symporter signature 11 31 7.9E-25 T 14-10-2018 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 7.9E-25 T 14-10-2018 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 PRINTS PR00173 Glutamate-aspartate symporter signature 86 111 7.9E-25 T 14-10-2018 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 7.9E-25 T 14-10-2018 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 7.9E-25 T 14-10-2018 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 PRINTS PR00173 Glutamate-aspartate symporter signature 364 384 7.9E-25 T 14-10-2018 A4R43_35115 75966d0d04b9a22fb5b6f764beeeb81a 450 PRINTS PR00173 Glutamate-aspartate symporter signature 53 73 7.9E-25 T 14-10-2018 A4R43_38235 d5c7213a13992dcc6d2dcc3a3d0b0a42 255 Pfam PF14011 EspG family 10 248 5.3E-40 T 14-10-2018 IPR025734 EspG family A4R43_29700 314b4e37c9b9685b5e31373252838b4f 145 Gene3D G3DSA:1.10.10.10 9 135 3.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29700 314b4e37c9b9685b5e31373252838b4f 145 SUPERFAMILY SSF46785 16 122 2.06E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_29700 314b4e37c9b9685b5e31373252838b4f 145 Pfam PF01638 HxlR-like helix-turn-helix 22 122 4.9E-11 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 SUPERFAMILY SSF46894 133 209 7.82E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 SUPERFAMILY SSF52172 1 122 3.27E-20 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 SMART SM00421 145 202 6.6E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 Pfam PF00072 Response regulator receiver domain 5 114 3.8E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 1.0E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 3.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 3.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 3.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 SMART SM00448 3 114 1.2E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_19470 3ae456fd458b362e8c03c2fbe4c825fa 228 Gene3D G3DSA:3.40.50.12740 3 208 1.7E-45 T 14-10-2018 A4R43_07075 700a47eac7ce2b427ca17eaf26e15dbd 383 Pfam PF01266 FAD dependent oxidoreductase 6 357 1.3E-57 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4R43_07075 700a47eac7ce2b427ca17eaf26e15dbd 383 Gene3D G3DSA:3.50.50.60 6 365 2.9E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07075 700a47eac7ce2b427ca17eaf26e15dbd 383 SUPERFAMILY SSF54373 217 319 1.83E-9 T 14-10-2018 A4R43_07075 700a47eac7ce2b427ca17eaf26e15dbd 383 SUPERFAMILY SSF51905 5 375 1.81E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_07075 700a47eac7ce2b427ca17eaf26e15dbd 383 Gene3D G3DSA:3.30.9.10 87 321 2.9E-81 T 14-10-2018 A4R43_15330 05ffbc5e9c7bccd4bd85597a34e4f697 201 SUPERFAMILY SSF46689 10 73 4.09E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_15330 05ffbc5e9c7bccd4bd85597a34e4f697 201 Gene3D G3DSA:1.10.357.10 9 199 2.8E-23 T 14-10-2018 A4R43_15330 05ffbc5e9c7bccd4bd85597a34e4f697 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.4E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15330 05ffbc5e9c7bccd4bd85597a34e4f697 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.4E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_15330 05ffbc5e9c7bccd4bd85597a34e4f697 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 6.5E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16610 40b34aff098524ec4866ba9a622069f0 386 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 303 1.1E-60 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16610 40b34aff098524ec4866ba9a622069f0 386 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 171 292 1.2E-7 T 14-10-2018 IPR024516 Mammalian cell entry, C-terminal A4R43_16610 40b34aff098524ec4866ba9a622069f0 386 Pfam PF02470 MlaD protein 43 116 1.6E-15 T 14-10-2018 IPR003399 Mce/MlaD A4R43_04455 dff41d3f9295ecbcfaae9e3397582d4b 173 Pfam PF13302 Acetyltransferase (GNAT) domain 12 147 2.1E-12 T 14-10-2018 IPR000182 GNAT domain A4R43_04455 dff41d3f9295ecbcfaae9e3397582d4b 173 SUPERFAMILY SSF55729 9 157 1.45E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_04455 dff41d3f9295ecbcfaae9e3397582d4b 173 Gene3D G3DSA:3.40.630.30 8 170 1.3E-25 T 14-10-2018 A4R43_37035 849f992e69be5d5257bdb598ae0da411 375 Pfam PF07730 Histidine kinase 181 244 3.4E-12 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_37035 849f992e69be5d5257bdb598ae0da411 375 SUPERFAMILY SSF55874 261 367 2.37E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_37035 849f992e69be5d5257bdb598ae0da411 375 Gene3D G3DSA:3.30.565.10 245 370 2.4E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_31500 f6f1dd2697740a83519aa34ed0ac76a7 272 Gene3D G3DSA:3.40.50.300 3 246 8.1E-53 T 14-10-2018 A4R43_31500 f6f1dd2697740a83519aa34ed0ac76a7 272 Pfam PF00005 ABC transporter 25 180 3.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_31500 f6f1dd2697740a83519aa34ed0ac76a7 272 SUPERFAMILY SSF52540 7 237 2.47E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31500 f6f1dd2697740a83519aa34ed0ac76a7 272 SMART SM00382 33 236 1.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_18230 696e122b15ed693e303d56c2fc7514f1 239 Gene3D G3DSA:3.40.50.10320 2 238 1.7E-74 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_18230 696e122b15ed693e303d56c2fc7514f1 239 SUPERFAMILY SSF102588 13 236 1.23E-45 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_18230 696e122b15ed693e303d56c2fc7514f1 239 Pfam PF02585 GlcNAc-PI de-N-acetylase 17 145 3.3E-24 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4R43_26825 770affb8659a2103f21783707632d803 264 Pfam PF14011 EspG family 2 254 5.4E-65 T 14-10-2018 IPR025734 EspG family A4R43_03890 7236a0a7b8b73fcdbb9ded095d3994ba 385 Gene3D G3DSA:3.30.565.10 255 379 1.9E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03890 7236a0a7b8b73fcdbb9ded095d3994ba 385 Pfam PF07730 Histidine kinase 181 244 5.6E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_03890 7236a0a7b8b73fcdbb9ded095d3994ba 385 SUPERFAMILY SSF55874 281 379 3.01E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_19665 1e4db67375544bb9e90907a9a6ec96b5 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 8.0E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19665 1e4db67375544bb9e90907a9a6ec96b5 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19665 1e4db67375544bb9e90907a9a6ec96b5 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19665 1e4db67375544bb9e90907a9a6ec96b5 198 SUPERFAMILY SSF46689 5 76 8.72E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19665 1e4db67375544bb9e90907a9a6ec96b5 198 Gene3D G3DSA:1.10.357.10 5 153 3.7E-25 T 14-10-2018 A4R43_11990 66129c62bd224ceafab617fa9746d275 288 SUPERFAMILY SSF161098 9 288 3.08E-63 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_11990 66129c62bd224ceafab617fa9746d275 288 Gene3D G3DSA:1.10.3720.10 3 278 4.5E-57 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_11990 66129c62bd224ceafab617fa9746d275 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 275 1.9E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_21175 d0412f19ffa6391f1572a08457c7a243 259 Gene3D G3DSA:2.60.40.10 141 258 2.2E-17 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_21175 d0412f19ffa6391f1572a08457c7a243 259 Pfam PF16158 Ig-like domain from next to BRCA1 gene 153 244 7.3E-16 T 14-10-2018 IPR032350 Next to BRCA1, central domain A4R43_17680 cc1cd7b02cb33508b494f3e0726f31ff 91 SUPERFAMILY SSF54909 2 77 4.61E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_17680 cc1cd7b02cb33508b494f3e0726f31ff 91 Gene3D G3DSA:3.30.70.920 3 78 1.4E-18 T 14-10-2018 A4R43_17680 cc1cd7b02cb33508b494f3e0726f31ff 91 Pfam PF01037 Lrp/AsnC ligand binding domain 9 76 5.8E-15 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_24265 46ac46f61af52d62e7bb46632ebeab4e 152 Gene3D G3DSA:1.10.10.60 42 89 4.1E-8 T 14-10-2018 A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 Pfam PF00085 Thioredoxin 5 103 2.5E-34 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 PIRSF PIRSF000077 1 107 4.2E-45 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 PRINTS PR00421 Thioredoxin family signature 31 40 2.3E-8 T 14-10-2018 A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 PRINTS PR00421 Thioredoxin family signature 23 31 2.3E-8 T 14-10-2018 A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 PRINTS PR00421 Thioredoxin family signature 71 82 2.3E-8 T 14-10-2018 A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 SUPERFAMILY SSF52833 4 107 5.74E-39 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 4.0E-40 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4R43_30485 1a0900f9067f4a82f0c17b73363a98ad 107 Gene3D G3DSA:3.40.30.10 1 106 4.7E-39 T 14-10-2018 A4R43_20750 31970d7866054179307871b31ee9e1be 214 SUPERFAMILY SSF142695 11 179 8.11E-55 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_20750 31970d7866054179307871b31ee9e1be 214 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 6 203 36.083 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_20750 31970d7866054179307871b31ee9e1be 214 Gene3D G3DSA:3.40.50.10990 7 181 6.5E-64 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_20750 31970d7866054179307871b31ee9e1be 214 Pfam PF00925 GTP cyclohydrolase II 12 177 5.7E-59 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4R43_05060 38f799dcc262c03c62da1a9a46da5876 428 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 15 426 3.4E-172 T 14-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A4R43_05060 38f799dcc262c03c62da1a9a46da5876 428 SUPERFAMILY SSF53383 12 421 5.68E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_05060 38f799dcc262c03c62da1a9a46da5876 428 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 235 254 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A4R43_05060 38f799dcc262c03c62da1a9a46da5876 428 Gene3D G3DSA:3.40.640.10 45 314 9.8E-169 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_05060 38f799dcc262c03c62da1a9a46da5876 428 Gene3D G3DSA:3.90.1150.10 17 417 9.8E-169 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_05060 38f799dcc262c03c62da1a9a46da5876 428 Pfam PF00266 Aminotransferase class-V 34 414 2.4E-138 T 14-10-2018 IPR000192 Aminotransferase class V domain A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 SUPERFAMILY SSF53300 469 605 9.05E-22 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 Gene3D G3DSA:3.40.50.410 469 639 1.7E-22 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 Gene3D G3DSA:3.40.50.300 2 202 6.5E-59 T 14-10-2018 A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 SMART SM00382 27 205 1.2E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 Pfam PF01078 Magnesium chelatase, subunit ChlI 114 182 2.6E-7 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 Gene3D G3DSA:1.10.8.80 247 337 2.9E-31 T 14-10-2018 A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 4 630 3.7E-241 T 14-10-2018 IPR012804 Cobaltochelatase subunit, putative A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 SUPERFAMILY SSF52540 2 327 6.63E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 Pfam PF13519 von Willebrand factor type A domain 469 575 1.4E-14 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_41540 397d1c73d95f46402546f77ca92e9c96 650 SMART SM00327 466 643 2.5E-19 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_41315 67f5de4310178dea85d58cda000d4fbb 286 Pfam PF04012 PspA/IM30 family 3 241 1.8E-48 T 14-10-2018 IPR007157 PspA/IM30 A4R43_12105 5cfc3435b999b896bf8a9fe38219231d 202 Pfam PF01810 LysE type translocator 16 199 9.3E-40 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_02470 d974881d3b9d477a327134eb5af3fa78 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 2.1E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_02470 d974881d3b9d477a327134eb5af3fa78 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 2.1E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_02470 d974881d3b9d477a327134eb5af3fa78 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 2.1E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_02470 d974881d3b9d477a327134eb5af3fa78 234 Gene3D G3DSA:3.40.50.1000 82 231 2.1E-23 T 14-10-2018 IPR023214 HAD superfamily A4R43_02470 d974881d3b9d477a327134eb5af3fa78 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 99 199 6.4E-9 T 14-10-2018 A4R43_02470 d974881d3b9d477a327134eb5af3fa78 234 SUPERFAMILY SSF56784 8 225 3.08E-24 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 Gene3D G3DSA:1.10.150.130 407 501 6.1E-7 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 Pfam PF08281 Sigma-70, region 4 102 154 3.9E-6 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 425 488 2.5E-7 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 33 64 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 SUPERFAMILY SSF56349 411 590 3.49E-12 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 Gene3D G3DSA:1.10.1740.10 4 80 1.0E-6 T 14-10-2018 A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 156 1.2E-13 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 SUPERFAMILY SSF88659 96 156 3.55E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 SUPERFAMILY SSF88946 10 96 7.06E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 Pfam PF04542 Sigma-70 region 2 23 78 4.1E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08525 b485f35f6d48ec1cf8051ee4b99065f7 653 Gene3D G3DSA:1.10.10.10 109 158 3.4E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_01785 513fe3ae0ec4b8dac1ef37d230d0b55d 158 SUPERFAMILY SSF54637 10 156 3.89E-38 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_01785 513fe3ae0ec4b8dac1ef37d230d0b55d 158 Pfam PF01575 MaoC like domain 17 131 3.8E-23 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_01785 513fe3ae0ec4b8dac1ef37d230d0b55d 158 Gene3D G3DSA:3.10.129.10 2 155 1.7E-44 T 14-10-2018 A4R43_40040 666f71440463acb86e66e2c10e642e38 354 SUPERFAMILY SSF51004 270 350 2.41E-7 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily A4R43_01275 1d7d27d61a84dc5c657daeda80575bf0 293 SUPERFAMILY SSF47413 9 68 6.68E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_01275 1d7d27d61a84dc5c657daeda80575bf0 293 Gene3D G3DSA:1.10.260.40 4 69 4.7E-7 T 14-10-2018 A4R43_23950 9cedd2b4e615e16466c1ee168e175301 198 SUPERFAMILY SSF53335 7 198 1.7E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_23950 9cedd2b4e615e16466c1ee168e175301 198 Gene3D G3DSA:3.40.50.150 10 190 5.2E-29 T 14-10-2018 A4R43_23950 9cedd2b4e615e16466c1ee168e175301 198 Pfam PF13649 Methyltransferase domain 38 133 4.6E-17 T 14-10-2018 A4R43_24835 bd850c55c867c843635e0ffdc513d5ec 281 SUPERFAMILY SSF56349 107 250 6.12E-5 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4R43_28565 ffb7dddbb21d6bcbed76e06570ce0e38 266 Pfam PF02517 CAAX protease self-immunity 162 249 5.7E-14 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A4R43_22810 764ccde6f1ffdb9524e628b30618bbfc 418 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_22810 764ccde6f1ffdb9524e628b30618bbfc 418 SUPERFAMILY SSF53383 10 413 9.0E-130 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_22810 764ccde6f1ffdb9524e628b30618bbfc 418 PIRSF PIRSF000521 108 415 3.4E-44 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_22810 764ccde6f1ffdb9524e628b30618bbfc 418 PIRSF PIRSF000521 7 114 1.5E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_22810 764ccde6f1ffdb9524e628b30618bbfc 418 Pfam PF00202 Aminotransferase class-III 12 410 5.1E-117 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_22810 764ccde6f1ffdb9524e628b30618bbfc 418 Gene3D G3DSA:3.40.640.10 48 311 1.0E-150 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_22810 764ccde6f1ffdb9524e628b30618bbfc 418 Gene3D G3DSA:3.90.1150.10 8 407 1.0E-150 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_05280 80d65aca0bdb2f935bc57bba6b0aa035 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 1.9E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05280 80d65aca0bdb2f935bc57bba6b0aa035 211 SUPERFAMILY SSF46689 23 96 5.64E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_05280 80d65aca0bdb2f935bc57bba6b0aa035 211 Gene3D G3DSA:1.10.357.10 17 210 6.6E-57 T 14-10-2018 A4R43_05280 80d65aca0bdb2f935bc57bba6b0aa035 211 SUPERFAMILY SSF48498 96 208 2.14E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_05280 80d65aca0bdb2f935bc57bba6b0aa035 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05280 80d65aca0bdb2f935bc57bba6b0aa035 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_34565 a0e7fa071fc2b4866e7a6ee0edd34949 105 Gene3D G3DSA:1.10.10.10 5 98 7.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34565 a0e7fa071fc2b4866e7a6ee0edd34949 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 3.2E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_34565 a0e7fa071fc2b4866e7a6ee0edd34949 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 3.2E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_34565 a0e7fa071fc2b4866e7a6ee0edd34949 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 3.2E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_34565 a0e7fa071fc2b4866e7a6ee0edd34949 105 SMART SM00418 21 98 2.5E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_34565 a0e7fa071fc2b4866e7a6ee0edd34949 105 SUPERFAMILY SSF46785 8 98 1.95E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_34565 a0e7fa071fc2b4866e7a6ee0edd34949 105 Pfam PF12840 Helix-turn-helix domain 22 77 1.0E-12 T 14-10-2018 A4R43_08485 2461ab71352a98bde25e04a48356393b 445 SUPERFAMILY SSF103473 7 442 3.53E-65 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08485 2461ab71352a98bde25e04a48356393b 445 Gene3D G3DSA:1.20.1250.20 256 443 1.1E-13 T 14-10-2018 A4R43_08485 2461ab71352a98bde25e04a48356393b 445 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 83 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_08485 2461ab71352a98bde25e04a48356393b 445 Gene3D G3DSA:1.20.1720.10 14 245 2.7E-46 T 14-10-2018 A4R43_08485 2461ab71352a98bde25e04a48356393b 445 Pfam PF07690 Major Facilitator Superfamily 18 400 6.4E-51 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_37940 10b75ed21c17f295cd5d189cbd6635d0 139 Pfam PF01042 Endoribonuclease L-PSP 22 135 2.0E-14 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4R43_37940 10b75ed21c17f295cd5d189cbd6635d0 139 SUPERFAMILY SSF55298 10 136 2.04E-24 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_37940 10b75ed21c17f295cd5d189cbd6635d0 139 Gene3D G3DSA:3.30.1330.40 10 138 1.5E-24 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_31580 eb919dbfeb622b6456ba92f8dfb87526 219 Pfam PF09335 SNARE associated Golgi protein 39 165 2.2E-22 T 14-10-2018 IPR032816 SNARE associated Golgi protein A4R43_37460 0dc6124920b9066f2a16d019552b8537 393 SUPERFAMILY SSF53474 13 340 9.97E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_37460 0dc6124920b9066f2a16d019552b8537 393 Pfam PF00561 alpha/beta hydrolase fold 44 156 1.6E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_37460 0dc6124920b9066f2a16d019552b8537 393 Gene3D G3DSA:3.40.50.1820 21 348 2.0E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38105 548ea680f9ef5fa38578ab79a42dc598 295 SUPERFAMILY SSF161098 20 295 1.12E-59 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_38105 548ea680f9ef5fa38578ab79a42dc598 295 Gene3D G3DSA:1.10.3720.10 15 285 3.3E-57 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_38105 548ea680f9ef5fa38578ab79a42dc598 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 280 3.8E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_04435 ef886d11d2f48d11f4250f2f4e1cbf29 289 Gene3D G3DSA:3.20.20.140 1 286 8.6E-51 T 14-10-2018 A4R43_04435 ef886d11d2f48d11f4250f2f4e1cbf29 289 SUPERFAMILY SSF51556 1 287 2.72E-43 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_04435 ef886d11d2f48d11f4250f2f4e1cbf29 289 Pfam PF04909 Amidohydrolase 72 278 8.2E-32 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_22120 32163c2e4c86d3b7d1abefd36106ff6c 376 Pfam PF01384 Phosphate transporter family 21 316 1.7E-79 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A4R43_18285 43ae5a6b39cdb7517f7bcaf4f782dd61 448 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_18285 43ae5a6b39cdb7517f7bcaf4f782dd61 448 Gene3D G3DSA:1.20.1250.20 12 441 1.3E-68 T 14-10-2018 A4R43_18285 43ae5a6b39cdb7517f7bcaf4f782dd61 448 SUPERFAMILY SSF103473 7 432 1.7E-65 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18285 43ae5a6b39cdb7517f7bcaf4f782dd61 448 Pfam PF00083 Sugar (and other) transporter 18 431 1.0E-29 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 9.7E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 SMART SM00448 4 116 8.0E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 SMART SM00421 151 208 7.1E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 Pfam PF00072 Response regulator receiver domain 6 117 7.8E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 Gene3D G3DSA:3.40.50.12740 4 213 8.4E-62 T 14-10-2018 A4R43_30665 f02351fa227f4e0a28dcd591294d1c31 216 SUPERFAMILY SSF52172 1 182 1.66E-32 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_35790 cf1b402a48a4a7023d6546112fe04ceb 186 Pfam PF03703 Bacterial PH domain 81 155 6.1E-14 T 14-10-2018 IPR005182 Domain of unknown function DUF304 A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 Gene3D G3DSA:1.20.1720.10 19 226 3.2E-49 T 14-10-2018 A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 424 1.4E-70 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 Pfam PF07690 Major Facilitator Superfamily 23 414 4.9E-55 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 SUPERFAMILY SSF103473 7 492 3.92E-71 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 82 104 3.8E-10 T 14-10-2018 A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 3.8E-10 T 14-10-2018 A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 3.8E-10 T 14-10-2018 A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 405 424 3.8E-10 T 14-10-2018 A4R43_22995 54c1af11ec7fb54a87750818b5efc414 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 342 362 3.8E-10 T 14-10-2018 A4R43_21100 d5835dec3cb898f8ed48b7df830c9999 73 Pfam PF12277 Protein of unknown function (DUF3618) 2 47 1.1E-18 T 14-10-2018 IPR022062 Protein of unknown function DUF3618 A4R43_28415 71cdd71433a8541410ea619dc536ce94 211 Pfam PF14016 Protein of unknown function (DUF4232) 75 209 1.6E-33 T 14-10-2018 IPR025326 Protein of unknown function DUF4232 A4R43_10270 17c66bb9c98f4aeb35c4aaeb27cf5d39 272 SUPERFAMILY SSF49899 49 271 1.67E-18 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_10270 17c66bb9c98f4aeb35c4aaeb27cf5d39 272 Pfam PF00722 Glycosyl hydrolases family 16 113 268 7.9E-8 T 14-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 A4R43_10270 17c66bb9c98f4aeb35c4aaeb27cf5d39 272 Gene3D G3DSA:2.60.120.200 27 272 5.3E-24 T 14-10-2018 A4R43_24735 927729a1f2ea59ed5ec487293e7a63a5 339 Pfam PF03741 Integral membrane protein TerC family 85 292 3.5E-46 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A4R43_24735 927729a1f2ea59ed5ec487293e7a63a5 339 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 20 329 4.2E-106 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 A4R43_14105 e5210e1d6da42bf8fcbd177cba9a03af 432 Gene3D G3DSA:1.10.10.10 22 85 5.1E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_14105 e5210e1d6da42bf8fcbd177cba9a03af 432 SUPERFAMILY SSF46785 25 81 3.2E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_14105 e5210e1d6da42bf8fcbd177cba9a03af 432 ProSitePatterns PS01125 ROK family signature. 225 252 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_14105 e5210e1d6da42bf8fcbd177cba9a03af 432 SUPERFAMILY SSF53067 90 405 4.75E-60 T 14-10-2018 A4R43_14105 e5210e1d6da42bf8fcbd177cba9a03af 432 Pfam PF00480 ROK family 93 404 6.7E-57 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4R43_14105 e5210e1d6da42bf8fcbd177cba9a03af 432 Gene3D G3DSA:3.30.420.40 215 389 4.0E-95 T 14-10-2018 A4R43_14105 e5210e1d6da42bf8fcbd177cba9a03af 432 Gene3D G3DSA:3.30.420.40 97 399 4.0E-95 T 14-10-2018 A4R43_29495 a65f60a32ebb2ffee36a44c0919fb37d 231 Gene3D G3DSA:3.40.50.300 9 228 7.8E-27 T 14-10-2018 A4R43_29495 a65f60a32ebb2ffee36a44c0919fb37d 231 SUPERFAMILY SSF52540 12 227 1.59E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29495 a65f60a32ebb2ffee36a44c0919fb37d 231 Pfam PF02223 Thymidylate kinase 20 169 7.2E-12 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A4R43_30570 091f100170999fb2d8c11cc54857b200 707 SUPERFAMILY SSF101478 383 681 3.66E-17 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_30570 091f100170999fb2d8c11cc54857b200 707 Pfam PF03747 ADP-ribosylglycohydrolase 414 665 6.4E-18 T 14-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 A4R43_30570 091f100170999fb2d8c11cc54857b200 707 Pfam PF15567 Immunity protein 35 4 97 1.8E-23 T 14-10-2018 IPR029082 Immunity protein 35 A4R43_30570 091f100170999fb2d8c11cc54857b200 707 Gene3D G3DSA:1.10.4080.10 378 688 1.2E-20 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_22000 abfe11b26f69e5ba12aeec7979d7272f 166 Pfam PF03551 Transcriptional regulator PadR-like family 11 81 9.2E-8 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_22000 abfe11b26f69e5ba12aeec7979d7272f 166 Gene3D G3DSA:1.10.10.10 6 88 6.3E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22000 abfe11b26f69e5ba12aeec7979d7272f 166 SUPERFAMILY SSF46785 8 162 4.73E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22780 a266a87d5d79a9cf5510c78598d279ea 246 PIRSF PIRSF015736 5 245 6.1E-58 T 14-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase A4R43_22780 a266a87d5d79a9cf5510c78598d279ea 246 Gene3D G3DSA:3.40.50.12500 14 246 3.5E-59 T 14-10-2018 A4R43_30585 eeed484a20d6429d04c0030238aeb741 2537 SUPERFAMILY SSF56399 1051 1212 1.07E-11 T 14-10-2018 A4R43_30585 eeed484a20d6429d04c0030238aeb741 2537 Pfam PF15644 Papain fold toxin 1, glutamine deamidase 1348 1457 3.5E-9 T 14-10-2018 IPR028908 Tox-PL domain A4R43_30585 eeed484a20d6429d04c0030238aeb741 2537 Pfam PF15644 Papain fold toxin 1, glutamine deamidase 1899 2001 3.6E-13 T 14-10-2018 IPR028908 Tox-PL domain A4R43_30585 eeed484a20d6429d04c0030238aeb741 2537 SUPERFAMILY SSF81301 2317 2471 5.72E-7 T 14-10-2018 A4R43_30585 eeed484a20d6429d04c0030238aeb741 2537 Gene3D G3DSA:3.90.176.10 1527 1730 9.0E-30 T 14-10-2018 A4R43_30585 eeed484a20d6429d04c0030238aeb741 2537 Gene3D G3DSA:3.90.176.10 990 1214 3.3E-36 T 14-10-2018 A4R43_30585 eeed484a20d6429d04c0030238aeb741 2537 SUPERFAMILY SSF56399 1572 1729 1.19E-6 T 14-10-2018 A4R43_33220 989ce7352623387abc2aa0be03f80d65 144 Pfam PF00934 PE family 46 131 7.6E-5 T 14-10-2018 IPR000084 PE-PGRS family, N-terminal A4R43_17210 95fb2932170e61a8968d4384a280c04a 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 250 2.5E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_17210 95fb2932170e61a8968d4384a280c04a 260 SUPERFAMILY SSF161098 52 240 1.7E-14 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_17210 95fb2932170e61a8968d4384a280c04a 260 Gene3D G3DSA:1.10.3720.10 48 256 5.0E-13 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_11405 2c32462ccc2a132f6b2358dbb1df87ba 250 Gene3D G3DSA:3.30.450.40 84 250 2.5E-53 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_11405 2c32462ccc2a132f6b2358dbb1df87ba 250 SMART SM00346 10 98 2.0E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_11405 2c32462ccc2a132f6b2358dbb1df87ba 250 Pfam PF01614 Bacterial transcriptional regulator 127 245 3.3E-28 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4R43_11405 2c32462ccc2a132f6b2358dbb1df87ba 250 SUPERFAMILY SSF55781 73 248 7.19E-45 T 14-10-2018 A4R43_11405 2c32462ccc2a132f6b2358dbb1df87ba 250 Pfam PF09339 IclR helix-turn-helix domain 13 63 5.8E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4R43_11405 2c32462ccc2a132f6b2358dbb1df87ba 250 Gene3D G3DSA:1.10.10.10 6 77 3.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11405 2c32462ccc2a132f6b2358dbb1df87ba 250 SUPERFAMILY SSF46785 12 82 3.47E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08390 03d4ed3fa9ee497ed62712b4cf796f98 252 SUPERFAMILY SSF52540 31 166 4.51E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_08390 03d4ed3fa9ee497ed62712b4cf796f98 252 Gene3D G3DSA:3.40.50.300 24 168 1.4E-19 T 14-10-2018 A4R43_08390 03d4ed3fa9ee497ed62712b4cf796f98 252 Pfam PF00265 Thymidine kinase 31 196 9.9E-20 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A4R43_36790 5dce8bfc4991a4f35e5241cf7e8f32b7 548 Pfam PF13408 Recombinase zinc beta ribbon domain 330 381 6.6E-7 T 14-10-2018 IPR025827 Recombinase zinc beta ribbon domain A4R43_36790 5dce8bfc4991a4f35e5241cf7e8f32b7 548 SUPERFAMILY SSF53041 1 149 8.11E-23 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4R43_36790 5dce8bfc4991a4f35e5241cf7e8f32b7 548 Pfam PF07508 Recombinase 203 308 4.1E-11 T 14-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A4R43_36790 5dce8bfc4991a4f35e5241cf7e8f32b7 548 Gene3D G3DSA:1.10.10.2600 136 332 1.8E-9 T 14-10-2018 IPR038109 DNA-binding recombinase domain superfamily A4R43_36790 5dce8bfc4991a4f35e5241cf7e8f32b7 548 Pfam PF00239 Resolvase, N terminal domain 1 148 8.3E-26 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4R43_36790 5dce8bfc4991a4f35e5241cf7e8f32b7 548 Gene3D G3DSA:3.40.50.1390 1 132 8.5E-26 T 14-10-2018 A4R43_36790 5dce8bfc4991a4f35e5241cf7e8f32b7 548 SMART SM00857 1 150 5.6E-30 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4R43_31965 fe6e62098fafa3bf832e5a41658a823e 180 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 29 172 4.8E-23 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 A4R43_20675 ee8e973954cfdeac719e0821c08b2b33 348 Gene3D G3DSA:2.40.440.10 191 332 3.3E-95 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_20675 ee8e973954cfdeac719e0821c08b2b33 348 Gene3D G3DSA:2.60.40.3710 99 344 3.3E-95 T 14-10-2018 A4R43_20675 ee8e973954cfdeac719e0821c08b2b33 348 Pfam PF03734 L,D-transpeptidase catalytic domain 197 317 2.4E-17 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4R43_20675 ee8e973954cfdeac719e0821c08b2b33 348 Gene3D G3DSA:2.60.40.3780 1 90 3.5E-29 T 14-10-2018 A4R43_20675 ee8e973954cfdeac719e0821c08b2b33 348 SUPERFAMILY SSF141523 191 317 6.28E-28 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 343 352 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 94 105 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 195 217 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 322 337 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 141 157 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 158 173 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 352 363 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 294 321 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00359 B-class P450 signature 276 287 3.2E-53 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00385 P450 superfamily signature 241 258 8.1E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00385 P450 superfamily signature 343 352 8.1E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00385 P450 superfamily signature 352 363 8.1E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 PRINTS PR00385 P450 superfamily signature 276 287 8.1E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 Pfam PF00067 Cytochrome P450 32 372 2.6E-24 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 Gene3D G3DSA:1.10.630.10 15 404 1.8E-118 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38425 672539bbf3029cb3962c2b715375b56b 404 SUPERFAMILY SSF48264 21 404 5.5E-91 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_36725 407720e8447ab00fb22a3fff3bba820d 653 Gene3D G3DSA:2.60.120.200 153 362 2.0E-15 T 14-10-2018 A4R43_36725 407720e8447ab00fb22a3fff3bba820d 653 SUPERFAMILY SSF49899 157 363 9.93E-14 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A4R43_36725 407720e8447ab00fb22a3fff3bba820d 653 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 198 358 1.7E-10 T 14-10-2018 A4R43_23005 4ba53c854c377470b262cd42c1e68e68 294 Pfam PF12730 ABC-2 family transporter protein 4 196 6.7E-7 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A4R43_39255 e308c7bafbedb83812780007e134dd5a 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 1.3E-34 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39255 e308c7bafbedb83812780007e134dd5a 104 SUPERFAMILY SSF141091 4 102 1.96E-32 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39255 e308c7bafbedb83812780007e134dd5a 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 14-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_39255 e308c7bafbedb83812780007e134dd5a 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 8.8E-26 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_39255 e308c7bafbedb83812780007e134dd5a 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 104 22.106 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_13140 f9a24d118d0bb81cc88383fbdcbe2ad2 137 Pfam PF02082 Transcriptional regulator 1 72 2.3E-18 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type A4R43_13140 f9a24d118d0bb81cc88383fbdcbe2ad2 137 SUPERFAMILY SSF46785 1 125 9.12E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13140 f9a24d118d0bb81cc88383fbdcbe2ad2 137 Gene3D G3DSA:1.10.10.10 1 129 1.7E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13985 b36e025ad56ad38985feb0314a84d67d 386 Pfam PF01757 Acyltransferase family 5 347 1.7E-25 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A4R43_07985 61f8df914f6267ffa6579579d2fc6ef4 290 Pfam PF13560 Helix-turn-helix domain 7 87 2.7E-17 T 14-10-2018 A4R43_07985 61f8df914f6267ffa6579579d2fc6ef4 290 SMART SM00530 11 84 6.3E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_07985 61f8df914f6267ffa6579579d2fc6ef4 290 Gene3D G3DSA:1.10.260.40 2 82 3.8E-8 T 14-10-2018 A4R43_07985 61f8df914f6267ffa6579579d2fc6ef4 290 SUPERFAMILY SSF47413 32 81 1.33E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_07985 61f8df914f6267ffa6579579d2fc6ef4 290 Gene3D G3DSA:3.30.450.180 110 277 1.4E-18 T 14-10-2018 A4R43_13620 f51bb618173de4c1a4deda8b4ee6f881 126 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 9 121 17.292 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4R43_13620 f51bb618173de4c1a4deda8b4ee6f881 126 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 11 116 5.3E-21 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4R43_07520 3c3f0a843189a8b26504ed3c8ec5718c 190 SUPERFAMILY SSF53697 2 185 1.62E-43 T 14-10-2018 A4R43_07520 3c3f0a843189a8b26504ed3c8ec5718c 190 Pfam PF13580 SIS domain 14 140 1.8E-24 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4R43_07520 3c3f0a843189a8b26504ed3c8ec5718c 190 Gene3D G3DSA:3.40.50.10490 1 185 1.7E-61 T 14-10-2018 A4R43_21835 53b4de994a925aca0daf5da53d06ff2e 522 Pfam PF07730 Histidine kinase 182 246 2.2E-8 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_21835 53b4de994a925aca0daf5da53d06ff2e 522 SUPERFAMILY SSF55874 268 376 1.38E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_21835 53b4de994a925aca0daf5da53d06ff2e 522 Gene3D G3DSA:3.30.565.10 251 376 2.2E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_35150 906cfa9ce767771855a69ab3aa149e0b 136 Pfam PF12680 SnoaL-like domain 19 118 1.0E-13 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_35150 906cfa9ce767771855a69ab3aa149e0b 136 Gene3D G3DSA:3.10.450.50 3 133 1.5E-36 T 14-10-2018 A4R43_35150 906cfa9ce767771855a69ab3aa149e0b 136 SUPERFAMILY SSF54427 3 132 3.99E-28 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_29190 1ab01dee1efd8369ce7bc91c99e88a1b 316 SUPERFAMILY SSF53686 3 311 2.88E-97 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_29190 1ab01dee1efd8369ce7bc91c99e88a1b 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 303 8.5E-85 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_29190 1ab01dee1efd8369ce7bc91c99e88a1b 316 Gene3D G3DSA:3.40.50.1100 13 307 3.4E-116 T 14-10-2018 A4R43_29190 1ab01dee1efd8369ce7bc91c99e88a1b 316 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4R43_29190 1ab01dee1efd8369ce7bc91c99e88a1b 316 Gene3D G3DSA:3.40.50.1100 50 146 3.4E-116 T 14-10-2018 A4R43_34340 f4f424ad9bb177c9b53bc774692de4de 131 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 34 122 9.0E-29 T 14-10-2018 IPR035165 Protein of unknown function DUF5319 A4R43_34340 f4f424ad9bb177c9b53bc774692de4de 131 Pfam PF17252 Family of unknown function (DUF5319) 7 126 7.6E-51 T 14-10-2018 IPR035165 Protein of unknown function DUF5319 A4R43_18795 ca1efc6bba5cbb76effef17c832c84bf 709 Pfam PF13538 UvrD-like helicase C-terminal domain 660 700 8.6E-9 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain A4R43_18795 ca1efc6bba5cbb76effef17c832c84bf 709 Gene3D G3DSA:3.40.50.300 180 372 9.8E-9 T 14-10-2018 A4R43_18795 ca1efc6bba5cbb76effef17c832c84bf 709 Gene3D G3DSA:3.40.50.300 562 708 3.2E-14 T 14-10-2018 A4R43_18795 ca1efc6bba5cbb76effef17c832c84bf 709 SUPERFAMILY SSF52540 184 706 8.09E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_18795 ca1efc6bba5cbb76effef17c832c84bf 709 Gene3D G3DSA:3.40.50.300 473 535 8.8E-7 T 14-10-2018 A4R43_18795 ca1efc6bba5cbb76effef17c832c84bf 709 Pfam PF13245 AAA domain 197 534 8.6E-10 T 14-10-2018 A4R43_16695 a0629d6591a736b6318b38800a72610a 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 255 2.5E-58 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_16695 a0629d6591a736b6318b38800a72610a 333 SUPERFAMILY SSF51735 11 326 7.02E-89 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_16695 a0629d6591a736b6318b38800a72610a 333 Gene3D G3DSA:3.90.25.10 179 308 1.1E-116 T 14-10-2018 A4R43_16695 a0629d6591a736b6318b38800a72610a 333 Gene3D G3DSA:3.40.50.720 13 255 1.1E-116 T 14-10-2018 A4R43_16695 a0629d6591a736b6318b38800a72610a 333 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 11 326 3.4E-116 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 A4R43_24595 b76319d7e9561ecd766f40f6562990c9 150 Gene3D G3DSA:3.90.79.10 11 142 1.8E-19 T 14-10-2018 A4R43_24595 b76319d7e9561ecd766f40f6562990c9 150 Pfam PF00293 NUDIX domain 14 124 1.6E-11 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_24595 b76319d7e9561ecd766f40f6562990c9 150 SUPERFAMILY SSF55811 7 129 8.8E-20 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_11085 bccce4faca87b1eab94229c14d76348a 315 Pfam PF01882 Protein of unknown function DUF58 54 138 4.8E-17 T 14-10-2018 IPR002881 Domain of unknown function DUF58 A4R43_29590 1d2d14676ff396fd4cb2b76eccfb2f85 349 Gene3D G3DSA:3.90.550.10 46 309 8.7E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_29590 1d2d14676ff396fd4cb2b76eccfb2f85 349 SUPERFAMILY SSF53448 48 303 1.22E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_29590 1d2d14676ff396fd4cb2b76eccfb2f85 349 Pfam PF00535 Glycosyl transferase family 2 52 163 1.0E-19 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_01270 2e3b7e937dd467e454802014c1d48e14 126 Pfam PF04149 Domain of unknown function (DUF397) 14 66 1.0E-5 T 14-10-2018 IPR007278 Domain of unknown function DUF397 A4R43_16310 111f9ed5c054a3942fce652be5089bbe 416 Gene3D G3DSA:3.20.20.80 54 406 2.1E-138 T 14-10-2018 A4R43_16310 111f9ed5c054a3942fce652be5089bbe 416 Pfam PF00704 Glycosyl hydrolases family 18 52 403 1.4E-73 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A4R43_16310 111f9ed5c054a3942fce652be5089bbe 416 SMART SM00636 50 403 5.5E-109 T 14-10-2018 IPR011583 Chitinase II GO:0008061 A4R43_16310 111f9ed5c054a3942fce652be5089bbe 416 SUPERFAMILY SSF51445 46 413 3.71E-81 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_16310 111f9ed5c054a3942fce652be5089bbe 416 ProSitePatterns PS01095 Chitinases family 18 active site. 185 193 - T 14-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A4R43_16310 111f9ed5c054a3942fce652be5089bbe 416 Gene3D G3DSA:3.10.50.10 318 378 2.1E-138 T 14-10-2018 IPR029070 Chitinase insertion domain superfamily A4R43_16310 111f9ed5c054a3942fce652be5089bbe 416 SUPERFAMILY SSF54556 315 374 6.34E-15 T 14-10-2018 IPR029070 Chitinase insertion domain superfamily A4R43_18515 f07fea8f09179dc283b9e6388115bf3d 265 SUPERFAMILY SSF53474 2 262 6.17E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_18515 f07fea8f09179dc283b9e6388115bf3d 265 Gene3D G3DSA:3.40.50.1820 1 262 8.1E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13720 f3d63f0c84924d94d12195acd46191ad 319 SUPERFAMILY SSF48452 74 284 1.52E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_13720 f3d63f0c84924d94d12195acd46191ad 319 Gene3D G3DSA:1.25.40.10 37 319 1.2E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_35390 ebc95e376111decd2624b78ac31fcc28 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 19 84 6.9E-14 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 A4R43_35390 ebc95e376111decd2624b78ac31fcc28 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 196 264 7.5E-17 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 A4R43_35390 ebc95e376111decd2624b78ac31fcc28 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 102 170 6.1E-11 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 A4R43_04025 3a7acd79d28e081504ae803c932292ab 313 Gene3D G3DSA:3.40.50.720 34 305 1.2E-90 T 14-10-2018 A4R43_04025 3a7acd79d28e081504ae803c932292ab 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_04025 3a7acd79d28e081504ae803c932292ab 313 Gene3D G3DSA:3.40.50.720 103 279 1.2E-90 T 14-10-2018 A4R43_04025 3a7acd79d28e081504ae803c932292ab 313 SUPERFAMILY SSF51735 103 282 6.84E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_04025 3a7acd79d28e081504ae803c932292ab 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 281 3.3E-45 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_04025 3a7acd79d28e081504ae803c932292ab 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 311 8.2E-30 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4R43_04025 3a7acd79d28e081504ae803c932292ab 313 SUPERFAMILY SSF52283 12 136 9.07E-34 T 14-10-2018 A4R43_04025 3a7acd79d28e081504ae803c932292ab 313 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4R43_41275 8d6fe04697a3a3f4eb354adac8c4a5de 157 Gene3D G3DSA:1.20.90.10 44 156 9.2E-41 T 14-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A4R43_41275 8d6fe04697a3a3f4eb354adac8c4a5de 157 Pfam PF09056 Prokaryotic phospholipase A2 52 155 1.3E-38 T 14-10-2018 IPR015141 Phospholipase A2, prokaryotic/fungal A4R43_41275 8d6fe04697a3a3f4eb354adac8c4a5de 157 SUPERFAMILY SSF48619 47 155 2.95E-31 T 14-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.711 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 Gene3D G3DSA:3.30.1550.10 5 75 8.0E-33 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 SUPERFAMILY SSF54747 5 75 1.44E-28 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 SUPERFAMILY SSF46906 70 143 3.79E-27 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 Gene3D G3DSA:1.10.10.250 76 143 3.9E-31 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 71 4.0E-13 T 14-10-2018 A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 3.0E-27 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 1.3E-27 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 SMART SM00649 12 143 4.0E-85 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4R43_33560 54634363dec0911207a7a79b2b2b0050 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 7.6E-63 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_00650 3db82210b85f9a558550a16495cf3fba 120 Pfam PF13411 MerR HTH family regulatory protein 1 66 6.3E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00650 3db82210b85f9a558550a16495cf3fba 120 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00650 3db82210b85f9a558550a16495cf3fba 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.1E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00650 3db82210b85f9a558550a16495cf3fba 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.1E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00650 3db82210b85f9a558550a16495cf3fba 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.1E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_00650 3db82210b85f9a558550a16495cf3fba 120 SUPERFAMILY SSF46955 1 113 1.39E-28 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_00650 3db82210b85f9a558550a16495cf3fba 120 Gene3D G3DSA:1.10.1660.10 1 120 1.2E-31 T 14-10-2018 A4R43_00650 3db82210b85f9a558550a16495cf3fba 120 SMART SM00422 1 69 1.2E-21 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_19525 76514fa341aa84f836870d5875d823c9 187 Pfam PF12028 Protein of unknown function (DUF3515) 21 181 3.9E-45 T 14-10-2018 IPR021903 Protein of unknown function DUF3515 A4R43_19460 205e248e4470a8763e16231c6e08f77a 415 Pfam PF07690 Major Facilitator Superfamily 33 377 9.3E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_19460 205e248e4470a8763e16231c6e08f77a 415 Gene3D G3DSA:1.20.1250.20 25 415 2.0E-65 T 14-10-2018 A4R43_19460 205e248e4470a8763e16231c6e08f77a 415 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_19460 205e248e4470a8763e16231c6e08f77a 415 SUPERFAMILY SSF103473 10 413 4.32E-70 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_37140 66c82c04e1959398a2b12898f6331481 349 Gene3D G3DSA:3.10.310.10 144 303 2.4E-34 T 14-10-2018 A4R43_37140 66c82c04e1959398a2b12898f6331481 349 SUPERFAMILY SSF54506 151 315 2.83E-27 T 14-10-2018 A4R43_37140 66c82c04e1959398a2b12898f6331481 349 SUPERFAMILY SSF54506 16 132 4.24E-14 T 14-10-2018 A4R43_37140 66c82c04e1959398a2b12898f6331481 349 Gene3D G3DSA:3.10.310.10 45 143 2.4E-34 T 14-10-2018 A4R43_37140 66c82c04e1959398a2b12898f6331481 349 Pfam PF04303 PrpF protein 46 315 5.3E-23 T 14-10-2018 IPR007400 PrpF protein A4R43_29940 6c09fcfe783ff4ce31f6c73384f10a66 531 Gene3D G3DSA:1.20.1250.20 270 496 9.6E-21 T 14-10-2018 A4R43_29940 6c09fcfe783ff4ce31f6c73384f10a66 531 Gene3D G3DSA:1.20.1720.10 19 211 9.1E-35 T 14-10-2018 A4R43_29940 6c09fcfe783ff4ce31f6c73384f10a66 531 SUPERFAMILY SSF103473 13 502 4.45E-57 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_29940 6c09fcfe783ff4ce31f6c73384f10a66 531 Pfam PF07690 Major Facilitator Superfamily 23 412 1.6E-43 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_41180 70ebb607d5348a9c91cd4cdd57c19422 164 Pfam PF04138 GtrA-like protein 38 151 1.9E-11 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4R43_21075 dd4048e69ccbb422ee15d4c3a5ac46a5 556 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 156 327 2.0E-40 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_21075 dd4048e69ccbb422ee15d4c3a5ac46a5 556 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 425 509 1.2E-17 T 14-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4R43_21075 dd4048e69ccbb422ee15d4c3a5ac46a5 556 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 156 327 2.9E-33 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_21075 dd4048e69ccbb422ee15d4c3a5ac46a5 556 Gene3D G3DSA:3.30.70.2390 425 521 1.7E-9 T 14-10-2018 A4R43_21075 dd4048e69ccbb422ee15d4c3a5ac46a5 556 Gene3D G3DSA:1.10.260.150 108 424 2.5E-67 T 14-10-2018 A4R43_31555 c2410bdb1b948004f43c46cadb64f9e1 174 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 54 3.0E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31555 c2410bdb1b948004f43c46cadb64f9e1 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 2.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31555 c2410bdb1b948004f43c46cadb64f9e1 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 2.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31555 c2410bdb1b948004f43c46cadb64f9e1 174 SUPERFAMILY SSF46689 3 67 7.48E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31555 c2410bdb1b948004f43c46cadb64f9e1 174 Gene3D G3DSA:1.10.357.10 3 173 1.9E-31 T 14-10-2018 A4R43_25110 a73d62c886fce1e6aa00450d0f80df68 571 Pfam PF13614 AAA domain 29 177 3.9E-9 T 14-10-2018 IPR025669 AAA domain A4R43_25110 a73d62c886fce1e6aa00450d0f80df68 571 Gene3D G3DSA:3.40.50.300 28 274 4.2E-34 T 14-10-2018 A4R43_25110 a73d62c886fce1e6aa00450d0f80df68 571 SUPERFAMILY SSF52540 29 256 2.98E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30670 d8da84d0556148230171f3d58097bebf 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 283 376 6.9E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_30670 d8da84d0556148230171f3d58097bebf 380 Gene3D G3DSA:3.30.565.10 245 376 3.0E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30670 d8da84d0556148230171f3d58097bebf 380 SUPERFAMILY SSF55874 276 375 4.06E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_31105 43d7aaeb5c7611f49e382a090354a821 153 SUPERFAMILY SSF55718 45 152 1.88E-19 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_31105 43d7aaeb5c7611f49e382a090354a821 153 Pfam PF02036 SCP-2 sterol transfer family 48 148 1.5E-12 T 14-10-2018 IPR003033 SCP2 sterol-binding domain A4R43_31105 43d7aaeb5c7611f49e382a090354a821 153 Gene3D G3DSA:3.30.1050.10 35 150 1.6E-20 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_14800 b06560baf486975402293832f218cff2 296 SUPERFAMILY SSF55729 97 285 2.44E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_14800 b06560baf486975402293832f218cff2 296 Gene3D G3DSA:3.40.630.30 129 285 1.4E-17 T 14-10-2018 A4R43_14800 b06560baf486975402293832f218cff2 296 Pfam PF00583 Acetyltransferase (GNAT) family 184 278 8.1E-5 T 14-10-2018 IPR000182 GNAT domain A4R43_29775 552122cc78d9ce10af83a65b8d98eeed 260 SUPERFAMILY SSF56281 19 247 3.41E-39 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_29775 552122cc78d9ce10af83a65b8d98eeed 260 Pfam PF00753 Metallo-beta-lactamase superfamily 35 238 1.6E-25 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_29775 552122cc78d9ce10af83a65b8d98eeed 260 SMART SM00849 35 244 6.5E-24 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_29775 552122cc78d9ce10af83a65b8d98eeed 260 Gene3D G3DSA:3.60.15.10 5 260 9.3E-70 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_40020 b8d94e582eb8c8ec7fd63e3f9f69d82d 153 Gene3D G3DSA:3.10.180.10 1 153 1.5E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_40020 b8d94e582eb8c8ec7fd63e3f9f69d82d 153 SUPERFAMILY SSF54593 10 152 5.47E-7 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_32290 96ebfb0f40266b760103be80b06a810f 213 SUPERFAMILY SSF55073 54 202 1.8E-38 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_32290 96ebfb0f40266b760103be80b06a810f 213 SMART SM00267 38 201 3.1E-39 T 14-10-2018 IPR000160 GGDEF domain A4R43_32290 96ebfb0f40266b760103be80b06a810f 213 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 50 200 2.3E-37 T 14-10-2018 IPR000160 GGDEF domain A4R43_32290 96ebfb0f40266b760103be80b06a810f 213 Gene3D G3DSA:3.30.70.270 35 201 2.0E-45 T 14-10-2018 A4R43_32290 96ebfb0f40266b760103be80b06a810f 213 Pfam PF00990 Diguanylate cyclase, GGDEF domain 51 196 1.9E-33 T 14-10-2018 IPR000160 GGDEF domain A4R43_27200 7298f342c0ee63d69cefd30f9caf40ba 261 Gene3D G3DSA:3.90.79.10 15 247 1.3E-65 T 14-10-2018 A4R43_27200 7298f342c0ee63d69cefd30f9caf40ba 261 SUPERFAMILY SSF55811 14 218 4.59E-15 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_20060 5cef3b1ad4420ebad9caddc5337bc233 217 SUPERFAMILY SSF55021 3 70 1.37E-6 T 14-10-2018 A4R43_30230 424b63e23a10029f3add3fa7b1e95db5 302 Pfam PF13586 Transposase DDE domain 199 295 2.9E-18 T 14-10-2018 IPR025668 Transposase DDE domain A4R43_30230 424b63e23a10029f3add3fa7b1e95db5 302 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 12 82 8.7E-23 T 14-10-2018 IPR025161 Putative transposase IS4/IS5 family A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 851 0.0 T 14-10-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 SUPERFAMILY SSF55486 213 460 1.29E-77 T 14-10-2018 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 Pfam PF01433 Peptidase family M1 domain 217 450 1.7E-57 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 Pfam PF11838 ERAP1-like C-terminal domain 534 842 7.1E-62 T 14-10-2018 IPR024571 ERAP1-like C-terminal domain A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 Gene3D G3DSA:1.10.390.60 210 455 2.2E-70 T 14-10-2018 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 SUPERFAMILY SSF63737 6 202 1.57E-39 T 14-10-2018 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 268 278 5.0E-22 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 185 200 5.0E-22 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 137 152 5.0E-22 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 302 317 5.0E-22 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 321 333 5.0E-22 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4R43_38880 22589ec298c6bb647605f12d2b5a144c 855 Gene3D G3DSA:2.60.40.1730 18 202 2.6E-28 T 14-10-2018 A4R43_10010 d0edd24b689a16e2d65f447b988a0a84 601 SMART SM00065 78 228 8.4E-23 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_10010 d0edd24b689a16e2d65f447b988a0a84 601 Gene3D G3DSA:3.30.450.40 53 232 6.1E-38 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_10010 d0edd24b689a16e2d65f447b988a0a84 601 Pfam PF13556 PucR C-terminal helix-turn-helix domain 532 590 2.8E-16 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_10010 d0edd24b689a16e2d65f447b988a0a84 601 Pfam PF13185 GAF domain 78 219 9.8E-21 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_10010 d0edd24b689a16e2d65f447b988a0a84 601 Gene3D G3DSA:1.10.10.2840 462 594 4.8E-18 T 14-10-2018 A4R43_10010 d0edd24b689a16e2d65f447b988a0a84 601 SUPERFAMILY SSF55781 57 227 1.72E-29 T 14-10-2018 A4R43_36845 6eaf4a51c5417cdfd247f2eec5167cdc 478 SUPERFAMILY SSF48208 170 458 7.85E-41 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_36845 6eaf4a51c5417cdfd247f2eec5167cdc 478 Gene3D G3DSA:1.50.10.20 142 478 1.0E-74 T 14-10-2018 A4R43_36845 6eaf4a51c5417cdfd247f2eec5167cdc 478 Pfam PF03663 Glycosyl hydrolase family 76 159 475 2.4E-40 T 14-10-2018 IPR005198 Glycoside hydrolase, family 76 A4R43_13085 3ba512a84d06df21f9f975ae35c3df7f 194 SUPERFAMILY SSF54427 13 142 2.33E-25 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_13085 3ba512a84d06df21f9f975ae35c3df7f 194 Pfam PF07366 SnoaL-like polyketide cyclase 28 142 2.9E-14 T 14-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 A4R43_13085 3ba512a84d06df21f9f975ae35c3df7f 194 Gene3D G3DSA:3.10.450.50 9 143 1.4E-22 T 14-10-2018 A4R43_24795 114d3e5d032828dc29970bca4e18d5ff 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24795 114d3e5d032828dc29970bca4e18d5ff 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 32 49 2.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24795 114d3e5d032828dc29970bca4e18d5ff 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24795 114d3e5d032828dc29970bca4e18d5ff 261 PIRSF PIRSF000094 1 257 3.0E-73 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A4R43_24795 114d3e5d032828dc29970bca4e18d5ff 261 Gene3D G3DSA:3.40.50.720 1 253 9.1E-44 T 14-10-2018 A4R43_24795 114d3e5d032828dc29970bca4e18d5ff 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 5.6E-65 T 14-10-2018 A4R43_24795 114d3e5d032828dc29970bca4e18d5ff 261 SUPERFAMILY SSF51735 3 252 8.0E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13160 43f43a5d2795301e2d196b62c9aaee50 403 Gene3D G3DSA:3.40.50.10540 5 395 5.2E-120 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_13160 43f43a5d2795301e2d196b62c9aaee50 403 Pfam PF02515 CoA-transferase family III 6 379 1.1E-111 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_13160 43f43a5d2795301e2d196b62c9aaee50 403 SUPERFAMILY SSF89796 5 403 7.59E-119 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_13160 43f43a5d2795301e2d196b62c9aaee50 403 Gene3D G3DSA:3.30.1540.10 230 328 5.2E-120 T 14-10-2018 A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.9E-16 T 14-10-2018 A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 286 3.9E-16 T 14-10-2018 A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 3.9E-16 T 14-10-2018 A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 302 3.9E-16 T 14-10-2018 A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 SUPERFAMILY SSF51905 5 362 4.32E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 Pfam PF01494 FAD binding domain 5 162 1.0E-12 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 Pfam PF01494 FAD binding domain 268 333 7.5E-13 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 Gene3D G3DSA:3.50.50.60 6 335 3.0E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00490 cc249e1c88f63e8cee04375d76fddd66 383 Gene3D G3DSA:3.30.9.30 37 262 3.0E-82 T 14-10-2018 A4R43_34140 653684117c057c2571aded24bc7761ed 813 SUPERFAMILY SSF140453 169 244 1.96E-5 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_34140 653684117c057c2571aded24bc7761ed 813 Gene3D G3DSA:1.10.287.1060 163 252 3.0E-6 T 14-10-2018 A4R43_41460 d4c7855b37596433cab37f83378abade 807 SUPERFAMILY SSF53187 223 515 2.22E-46 T 14-10-2018 A4R43_41460 d4c7855b37596433cab37f83378abade 807 Gene3D G3DSA:3.40.630.10 220 528 1.8E-60 T 14-10-2018 A4R43_41460 d4c7855b37596433cab37f83378abade 807 SMART SM00631 225 523 4.7E-25 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_41460 d4c7855b37596433cab37f83378abade 807 Gene3D G3DSA:2.60.120.380 669 741 5.2E-8 T 14-10-2018 A4R43_41460 d4c7855b37596433cab37f83378abade 807 Pfam PF00246 Zinc carboxypeptidase 236 516 1.3E-42 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_37995 703f3b6673c5840001de2ed27350ab5e 149 Gene3D G3DSA:1.10.260.40 3 142 1.5E-40 T 14-10-2018 A4R43_37995 703f3b6673c5840001de2ed27350ab5e 149 SUPERFAMILY SSF47413 42 83 1.83E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_03300 398df58ada12fe482cb88092b341270b 243 Gene3D G3DSA:2.160.20.10 28 243 1.0E-71 T 14-10-2018 IPR012334 Pectin lyase fold A4R43_03300 398df58ada12fe482cb88092b341270b 243 SUPERFAMILY SSF51126 33 200 4.71E-52 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_03300 398df58ada12fe482cb88092b341270b 243 Pfam PF03211 Pectate lyase 19 215 3.5E-73 T 14-10-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 A4R43_06715 8d30f20d7170ddaa3ca3dfdb891c10ed 373 ProSitePatterns PS00876 Indoleamine 2,3-dioxygenase signature 1. 247 257 - T 14-10-2018 IPR000898 Indoleamine 2,3-dioxygenase GO:0020037 Reactome: R-HSA-71240 A4R43_06715 8d30f20d7170ddaa3ca3dfdb891c10ed 373 Gene3D G3DSA:1.20.58.480 137 370 1.1E-52 T 14-10-2018 A4R43_06715 8d30f20d7170ddaa3ca3dfdb891c10ed 373 Pfam PF01231 Indoleamine 2,3-dioxygenase 6 338 8.1E-89 T 14-10-2018 IPR000898 Indoleamine 2,3-dioxygenase GO:0020037 Reactome: R-HSA-71240 A4R43_06715 8d30f20d7170ddaa3ca3dfdb891c10ed 373 SUPERFAMILY SSF140959 7 369 3.14E-91 T 14-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A4R43_10730 384e92e4b0e3b2cc4fe0e8f004c9737b 107 Pfam PF02416 mttA/Hcf106 family 6 51 2.3E-18 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A4R43_10730 384e92e4b0e3b2cc4fe0e8f004c9737b 107 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 73 20.743 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4R43_10730 384e92e4b0e3b2cc4fe0e8f004c9737b 107 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 1.6E-18 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4R43_09020 9299255c20fac0b3a080361939016888 329 SUPERFAMILY SSF51735 5 156 3.63E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_09020 9299255c20fac0b3a080361939016888 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 56.47 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A4R43_09020 9299255c20fac0b3a080361939016888 329 PIRSF PIRSF000102 2 328 4.5E-59 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4R43_09020 9299255c20fac0b3a080361939016888 329 Gene3D G3DSA:3.40.50.720 1 155 1.1E-51 T 14-10-2018 A4R43_09020 9299255c20fac0b3a080361939016888 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 146 2.7E-30 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_09020 9299255c20fac0b3a080361939016888 329 SUPERFAMILY SSF56327 157 326 3.24E-60 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4R43_09020 9299255c20fac0b3a080361939016888 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 14-10-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4R43_09020 9299255c20fac0b3a080361939016888 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 324 3.8E-32 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A4R43_09020 9299255c20fac0b3a080361939016888 329 Gene3D G3DSA:3.90.110.10 156 329 1.1E-65 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4R43_09020 9299255c20fac0b3a080361939016888 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 8.0E-143 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A4R43_28875 98dd2fb790833ca187cfad2ac00774d7 393 SUPERFAMILY SSF52540 20 259 6.86E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_28875 98dd2fb790833ca187cfad2ac00774d7 393 Gene3D G3DSA:3.40.50.300 19 299 1.1E-72 T 14-10-2018 A4R43_28875 98dd2fb790833ca187cfad2ac00774d7 393 SUPERFAMILY SSF54631 269 384 2.32E-8 T 14-10-2018 A4R43_28875 98dd2fb790833ca187cfad2ac00774d7 393 Pfam PF00005 ABC transporter 38 183 5.3E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_28875 98dd2fb790833ca187cfad2ac00774d7 393 SMART SM00382 46 242 1.7E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_28875 98dd2fb790833ca187cfad2ac00774d7 393 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_39160 08a873622de98a7a49a5890f1aa24e5b 283 Pfam PF01261 Xylose isomerase-like TIM barrel 27 212 2.2E-23 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_39160 08a873622de98a7a49a5890f1aa24e5b 283 SUPERFAMILY SSF51658 2 257 2.49E-52 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_39160 08a873622de98a7a49a5890f1aa24e5b 283 Gene3D G3DSA:3.20.20.150 1 281 6.4E-67 T 14-10-2018 A4R43_09930 cc89d8190edbd2849dbd9582deafba15 394 Pfam PF00425 chorismate binding enzyme 121 380 1.7E-71 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A4R43_09930 cc89d8190edbd2849dbd9582deafba15 394 Gene3D G3DSA:3.60.120.10 12 391 1.9E-117 T 14-10-2018 IPR005801 ADC synthase GO:0009058 A4R43_09930 cc89d8190edbd2849dbd9582deafba15 394 PRINTS PR00095 Anthranilate synthase component I signature 337 351 3.0E-5 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_09930 cc89d8190edbd2849dbd9582deafba15 394 PRINTS PR00095 Anthranilate synthase component I signature 322 336 3.0E-5 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_09930 cc89d8190edbd2849dbd9582deafba15 394 PRINTS PR00095 Anthranilate synthase component I signature 229 242 3.0E-5 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4R43_09930 cc89d8190edbd2849dbd9582deafba15 394 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 118 388 3.3E-78 T 14-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A4R43_09930 cc89d8190edbd2849dbd9582deafba15 394 SUPERFAMILY SSF56322 111 390 2.35E-87 T 14-10-2018 IPR005801 ADC synthase GO:0009058 A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 Pfam PF01029 NusB family 5 115 7.9E-22 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 220 234 3.9E-20 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 263 3.9E-20 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 366 382 3.9E-20 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 417 434 3.9E-20 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 328 3.9E-20 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 SUPERFAMILY SSF53335 132 434 2.5E-52 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 Pfam PF01189 16S rRNA methyltransferase RsmB/F 249 433 4.6E-47 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 SUPERFAMILY SSF48013 1 147 2.45E-28 T 14-10-2018 IPR035926 NusB-like superfamily A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 Gene3D G3DSA:1.10.940.10 1 130 1.8E-36 T 14-10-2018 IPR035926 NusB-like superfamily A4R43_04795 68dc0106707d94ac15060b55f6d27d0c 438 Gene3D G3DSA:3.40.50.150 139 434 4.3E-57 T 14-10-2018 A4R43_05720 8b454094ad109b2f2eb9fa629a9f00a8 264 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 147 167 - T 14-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site A4R43_05720 8b454094ad109b2f2eb9fa629a9f00a8 264 SUPERFAMILY SSF56317 2 256 4.06E-66 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_05720 8b454094ad109b2f2eb9fa629a9f00a8 264 Pfam PF00795 Carbon-nitrogen hydrolase 4 249 5.8E-44 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_05720 8b454094ad109b2f2eb9fa629a9f00a8 264 Gene3D G3DSA:3.60.110.10 1 264 4.2E-71 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_21290 b4c745af10f9b33e4854bd166404529e 382 Pfam PF13556 PucR C-terminal helix-turn-helix domain 315 359 3.6E-17 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_21290 b4c745af10f9b33e4854bd166404529e 382 Gene3D G3DSA:1.10.10.2840 249 374 5.2E-21 T 14-10-2018 A4R43_18240 e9e681abba8b9e723d7042cf7e4468bb 141 SUPERFAMILY SSF55729 10 140 1.61E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_18240 e9e681abba8b9e723d7042cf7e4468bb 141 Pfam PF13673 Acetyltransferase (GNAT) domain 68 140 1.2E-15 T 14-10-2018 IPR000182 GNAT domain A4R43_18240 e9e681abba8b9e723d7042cf7e4468bb 141 Gene3D G3DSA:3.40.630.30 2 141 3.3E-36 T 14-10-2018 A4R43_16620 2cfe8d419503ddcd0abae54485c1ec19 343 Pfam PF02470 MlaD protein 40 112 1.0E-14 T 14-10-2018 IPR003399 Mce/MlaD A4R43_16620 2cfe8d419503ddcd0abae54485c1ec19 343 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 3.4E-10 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16620 2cfe8d419503ddcd0abae54485c1ec19 343 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 3.4E-10 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16620 2cfe8d419503ddcd0abae54485c1ec19 343 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 3.4E-10 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16620 2cfe8d419503ddcd0abae54485c1ec19 343 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 297 316 3.4E-10 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16620 2cfe8d419503ddcd0abae54485c1ec19 343 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 3.4E-10 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16620 2cfe8d419503ddcd0abae54485c1ec19 343 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 3.4E-10 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16620 2cfe8d419503ddcd0abae54485c1ec19 343 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 291 3.9E-61 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 Gene3D G3DSA:3.40.50.12740 2 212 2.0E-65 T 14-10-2018 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 Pfam PF00072 Response regulator receiver domain 4 116 8.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 SMART SM00421 149 206 6.6E-27 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 8.0E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 SMART SM00448 2 116 1.5E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 SUPERFAMILY SSF46894 140 211 1.9E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_32435 74df87c34a3bd8298ec1100487f1f510 212 SUPERFAMILY SSF52172 1 135 5.12E-31 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_28490 4caa1dae07135d3b50229fa0394fc8c6 560 SUPERFAMILY SSF48371 225 559 5.75E-5 T 14-10-2018 IPR016024 Armadillo-type fold A4R43_21250 2e801224ee048b65113ea005e923f74d 328 Gene3D G3DSA:1.10.510.10 166 312 2.7E-12 T 14-10-2018 A4R43_21250 2e801224ee048b65113ea005e923f74d 328 SUPERFAMILY SSF56112 86 309 5.05E-17 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_21250 2e801224ee048b65113ea005e923f74d 328 SUPERFAMILY SSF46565 29 76 1.1E-6 T 14-10-2018 IPR036869 Chaperone J-domain superfamily A4R43_31785 137dcb4ef2cb0138f3cbb7117ad89608 255 SUPERFAMILY SSF53850 1 243 4.47E-60 T 14-10-2018 A4R43_31785 137dcb4ef2cb0138f3cbb7117ad89608 255 Gene3D G3DSA:3.40.190.10 112 204 4.0E-60 T 14-10-2018 A4R43_31785 137dcb4ef2cb0138f3cbb7117ad89608 255 SMART SM00062 27 246 5.6E-51 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_31785 137dcb4ef2cb0138f3cbb7117ad89608 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 243 9.2E-55 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_31785 137dcb4ef2cb0138f3cbb7117ad89608 255 Gene3D G3DSA:3.40.190.10 28 242 4.0E-60 T 14-10-2018 A4R43_07080 d7d39141397c959712d30e9b0a9b9376 89 Gene3D G3DSA:3.10.20.440 2 88 2.8E-18 T 14-10-2018 A4R43_07080 d7d39141397c959712d30e9b0a9b9376 89 SUPERFAMILY SSF54292 6 84 3.68E-16 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_07080 d7d39141397c959712d30e9b0a9b9376 89 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 83 5.8E-23 T 14-10-2018 A4R43_31035 f50d845b638c576a3f50a0b55eaaf444 547 Gene3D G3DSA:1.20.1730.10 33 475 5.0E-31 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_31035 f50d845b638c576a3f50a0b55eaaf444 547 Pfam PF00474 Sodium:solute symporter family 43 448 4.7E-17 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_36550 a2fbf0ef7319c694d1afe9b8c3fd76bc 211 SUPERFAMILY SSF46689 18 89 2.33E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_36550 a2fbf0ef7319c694d1afe9b8c3fd76bc 211 Gene3D G3DSA:1.10.10.60 12 68 2.3E-14 T 14-10-2018 A4R43_36550 a2fbf0ef7319c694d1afe9b8c3fd76bc 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_36550 a2fbf0ef7319c694d1afe9b8c3fd76bc 211 Gene3D G3DSA:1.10.357.10 69 201 7.1E-9 T 14-10-2018 A4R43_23410 1160b0c59655dc511f0c8d36070ea61e 523 SUPERFAMILY SSF161098 5 245 5.34E-42 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23410 1160b0c59655dc511f0c8d36070ea61e 523 Gene3D G3DSA:1.10.3720.10 7 248 1.4E-47 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23410 1160b0c59655dc511f0c8d36070ea61e 523 Gene3D G3DSA:1.10.3720.10 265 519 1.0E-37 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23410 1160b0c59655dc511f0c8d36070ea61e 523 SUPERFAMILY SSF161098 264 516 3.49E-34 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23410 1160b0c59655dc511f0c8d36070ea61e 523 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 243 8.3E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_23410 1160b0c59655dc511f0c8d36070ea61e 523 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 342 514 1.5E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_27005 976edc730c15f7f481ee6bdc63b86a98 111 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 2 106 1.1E-24 T 14-10-2018 IPR021202 Apoptosis inhibitor Rv3654c-like A4R43_27005 976edc730c15f7f481ee6bdc63b86a98 111 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 2 46 3.4E-5 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal A4R43_17970 9eb0b43853633eb6ec5e907c04fd84ee 277 SUPERFAMILY SSF53474 27 273 4.09E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_17970 9eb0b43853633eb6ec5e907c04fd84ee 277 Gene3D G3DSA:3.40.50.1820 1 273 1.9E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_17970 9eb0b43853633eb6ec5e907c04fd84ee 277 Pfam PF12697 Alpha/beta hydrolase family 44 257 8.4E-15 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_17970 9eb0b43853633eb6ec5e907c04fd84ee 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 127 140 3.9E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_17970 9eb0b43853633eb6ec5e907c04fd84ee 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 3.9E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_17970 9eb0b43853633eb6ec5e907c04fd84ee 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 3.9E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_40595 7a27a78cf3dbc4f9e9f276e066d5566e 285 Pfam PF00753 Metallo-beta-lactamase superfamily 22 188 2.3E-14 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_40595 7a27a78cf3dbc4f9e9f276e066d5566e 285 SUPERFAMILY SSF56281 23 256 2.03E-40 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_40595 7a27a78cf3dbc4f9e9f276e066d5566e 285 Gene3D G3DSA:3.60.15.10 4 239 3.6E-37 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_40595 7a27a78cf3dbc4f9e9f276e066d5566e 285 SMART SM00849 22 215 7.1E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00385 P450 superfamily signature 302 313 4.3E-9 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00385 P450 superfamily signature 377 386 4.3E-9 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00385 P450 superfamily signature 250 267 4.3E-9 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00385 P450 superfamily signature 386 397 4.3E-9 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 SUPERFAMILY SSF48264 3 437 3.67E-107 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 Pfam PF00067 Cytochrome P450 5 422 1.1E-77 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00463 E-class P450 group I signature 376 386 1.9E-26 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00463 E-class P450 group I signature 259 285 1.9E-26 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00463 E-class P450 group I signature 26 45 1.9E-26 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00463 E-class P450 group I signature 239 256 1.9E-26 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00463 E-class P450 group I signature 386 409 1.9E-26 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 PRINTS PR00463 E-class P450 group I signature 341 365 1.9E-26 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_04575 db93774689b42f1c8c5e058a7238595f 445 Gene3D G3DSA:1.10.630.10 1 441 1.8E-128 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_17295 71f1270f78a99996f268f91dad269d3c 127 Gene3D G3DSA:2.30.110.10 2 126 1.7E-19 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_17295 71f1270f78a99996f268f91dad269d3c 127 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 1 126 2.1E-43 T 14-10-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative A4R43_17295 71f1270f78a99996f268f91dad269d3c 127 SUPERFAMILY SSF50475 5 126 1.25E-18 T 14-10-2018 A4R43_17295 71f1270f78a99996f268f91dad269d3c 127 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 87 7.0E-9 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_32185 43159a03c6989ac2760595bce1940e59 166 Gene3D G3DSA:3.30.565.10 8 118 1.9E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_17795 43e1b8d00b19a0d2f84488dfae5ede67 200 Pfam PF04167 Protein of unknown function (DUF402) 88 146 8.2E-12 T 14-10-2018 IPR007295 Domain of unknown function DUF402 A4R43_17795 43e1b8d00b19a0d2f84488dfae5ede67 200 Gene3D G3DSA:2.40.380.10 2 194 1.8E-60 T 14-10-2018 IPR035930 FomD-like superfamily A4R43_17795 43e1b8d00b19a0d2f84488dfae5ede67 200 SUPERFAMILY SSF159234 10 196 1.44E-29 T 14-10-2018 IPR035930 FomD-like superfamily A4R43_35400 31500ff9b1086213d45b667b0fb1a5c6 234 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 13 230 5.5E-56 T 14-10-2018 IPR017523 Conserved hypothetical protein CHP03089 A4R43_35400 31500ff9b1086213d45b667b0fb1a5c6 234 SUPERFAMILY SSF56801 5 231 1.31E-19 T 14-10-2018 A4R43_35400 31500ff9b1086213d45b667b0fb1a5c6 234 Gene3D G3DSA:3.40.50.12780 6 234 2.2E-10 T 14-10-2018 A4R43_17000 4d89c61068afa5de9789f832492216c3 254 SUPERFAMILY SSF109854 8 140 1.74E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_17000 4d89c61068afa5de9789f832492216c3 254 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 17 227 5.6E-18 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4R43_17000 4d89c61068afa5de9789f832492216c3 254 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 25 133 2.5E-13 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_17000 4d89c61068afa5de9789f832492216c3 254 Pfam PF07398 MDMPI C-terminal domain 147 238 2.3E-10 T 14-10-2018 IPR010872 MDMPI C-terminal A4R43_41490 55a74d1e9d5b9606a19dd995985d6638 284 PIRSF PIRSF006648 16 267 7.0E-20 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_41490 55a74d1e9d5b9606a19dd995985d6638 284 Pfam PF01061 ABC-2 type transporter 31 220 8.9E-19 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_27020 ca93031f92c2f07e7c793ab161024c97 208 Pfam PF00482 Type II secretion system (T2SS), protein F 50 162 6.8E-9 T 14-10-2018 IPR018076 Type II secretion system F domain A4R43_00535 1160a7b221f3bc3a5a2d815dfa8f78bf 298 Pfam PF07859 alpha/beta hydrolase fold 69 272 6.6E-69 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_00535 1160a7b221f3bc3a5a2d815dfa8f78bf 298 Gene3D G3DSA:3.40.50.1820 1 297 5.1E-88 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00535 1160a7b221f3bc3a5a2d815dfa8f78bf 298 SUPERFAMILY SSF53474 28 278 7.25E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_04855 b5cabc886c32ddbf330c345e69dee72b 328 Gene3D G3DSA:3.40.50.12300 1 311 4.6E-95 T 14-10-2018 IPR038136 Gluconeogenesis factor superfamily A4R43_04855 b5cabc886c32ddbf330c345e69dee72b 328 Pfam PF01933 Uncharacterised protein family UPF0052 4 276 2.8E-71 T 14-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 A4R43_04855 b5cabc886c32ddbf330c345e69dee72b 328 SUPERFAMILY SSF142338 2 307 2.09E-83 T 14-10-2018 A4R43_04855 b5cabc886c32ddbf330c345e69dee72b 328 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 4 273 4.1E-85 T 14-10-2018 IPR010119 Gluconeogenesis factor A4R43_04855 b5cabc886c32ddbf330c345e69dee72b 328 Hamap MF_00973 Gluconeogenesis factor. 1 312 30.783 T 14-10-2018 IPR010119 Gluconeogenesis factor A4R43_08435 15cbb366d1956b1e6784e263486fc73f 276 Gene3D G3DSA:3.40.50.150 6 269 4.4E-44 T 14-10-2018 A4R43_08435 15cbb366d1956b1e6784e263486fc73f 276 Pfam PF08241 Methyltransferase domain 58 154 8.2E-23 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_08435 15cbb366d1956b1e6784e263486fc73f 276 SUPERFAMILY SSF53335 25 254 1.01E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_26220 046c5310c5563bf45e14b63c472043a2 220 Pfam PF11361 Protein of unknown function (DUF3159) 12 197 5.5E-51 T 14-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 A4R43_40235 af2a10ae42d16458fe715281a2721e00 298 SUPERFAMILY SSF56112 34 277 4.46E-23 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_40235 af2a10ae42d16458fe715281a2721e00 298 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 44 272 5.6E-14 T 14-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 A4R43_40235 af2a10ae42d16458fe715281a2721e00 298 Gene3D G3DSA:3.90.1200.10 148 249 1.2E-8 T 14-10-2018 A4R43_11750 724f6b149d4de934adf34776eb1f07d9 235 SUPERFAMILY SSF49879 35 91 1.83E-6 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 A4R43_13730 6a8a47362d9ed40c45f9a57d6b28ad8a 357 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 30 38 - T 14-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A4R43_13730 6a8a47362d9ed40c45f9a57d6b28ad8a 357 SUPERFAMILY SSF50249 198 335 2.23E-10 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_13730 6a8a47362d9ed40c45f9a57d6b28ad8a 357 Gene3D G3DSA:3.30.470.30 9 195 3.3E-40 T 14-10-2018 A4R43_13730 6a8a47362d9ed40c45f9a57d6b28ad8a 357 Pfam PF01068 ATP dependent DNA ligase domain 12 195 2.7E-32 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A4R43_13730 6a8a47362d9ed40c45f9a57d6b28ad8a 357 Pfam PF04679 ATP dependent DNA ligase C terminal region 216 327 6.2E-14 T 14-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A4R43_13730 6a8a47362d9ed40c45f9a57d6b28ad8a 357 SUPERFAMILY SSF56091 7 195 2.64E-42 T 14-10-2018 A4R43_13730 6a8a47362d9ed40c45f9a57d6b28ad8a 357 Gene3D G3DSA:2.40.50.140 197 334 7.8E-24 T 14-10-2018 A4R43_28525 07c350fde120b7b47767180ae15334e2 106 Gene3D G3DSA:3.30.70.120 1 106 1.8E-36 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4R43_28525 07c350fde120b7b47767180ae15334e2 106 SUPERFAMILY SSF54913 4 105 8.9E-34 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4R43_28525 07c350fde120b7b47767180ae15334e2 106 Pfam PF03091 CutA1 divalent ion tolerance protein 6 103 5.9E-34 T 14-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 A4R43_25440 ff2376e5d5f0c3b1a86c2cd511b33ba5 374 Gene3D G3DSA:3.60.60.10 82 367 2.2E-35 T 14-10-2018 A4R43_25440 ff2376e5d5f0c3b1a86c2cd511b33ba5 374 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 105 350 1.0E-16 T 14-10-2018 IPR005079 Peptidase C45 A4R43_25440 ff2376e5d5f0c3b1a86c2cd511b33ba5 374 SUPERFAMILY SSF56235 160 275 2.01E-14 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_28985 1bd355da0faafde6e8f7e82d4c915e09 352 SUPERFAMILY SSF51621 26 288 3.45E-53 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_28985 1bd355da0faafde6e8f7e82d4c915e09 352 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 30 194 5.7E-30 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_28985 1bd355da0faafde6e8f7e82d4c915e09 352 Gene3D G3DSA:3.20.20.60 1 349 7.0E-119 T 14-10-2018 A4R43_28985 1bd355da0faafde6e8f7e82d4c915e09 352 PIRSF PIRSF015582 14 348 1.3E-84 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like A4R43_24620 7206f62c8bb0da0c9d61a2fd0b60f99a 455 PIRSF PIRSF004810 1 451 5.6E-120 T 14-10-2018 IPR014047 Chromate transporter, long chain A4R43_24620 7206f62c8bb0da0c9d61a2fd0b60f99a 455 Pfam PF02417 Chromate transporter 252 443 6.7E-33 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A4R43_24620 7206f62c8bb0da0c9d61a2fd0b60f99a 455 Pfam PF02417 Chromate transporter 17 178 4.3E-32 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A4R43_24620 7206f62c8bb0da0c9d61a2fd0b60f99a 455 TIGRFAM TIGR00937 2A51: chromate efflux transporter 24 390 8.6E-65 T 14-10-2018 IPR014047 Chromate transporter, long chain A4R43_39595 e431193a1c90ed68ebb94e4fd9f815d8 332 Pfam PF00296 Luciferase-like monooxygenase 9 305 1.3E-50 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_39595 e431193a1c90ed68ebb94e4fd9f815d8 332 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 329 5.8E-171 T 14-10-2018 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 A4R43_39595 e431193a1c90ed68ebb94e4fd9f815d8 332 Gene3D G3DSA:3.20.20.30 1 329 6.4E-66 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_39595 e431193a1c90ed68ebb94e4fd9f815d8 332 SUPERFAMILY SSF51679 2 324 1.57E-52 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_09920 91346d72b561564273684e4cd9f85aa9 222 SUPERFAMILY SSF52499 2 212 6.41E-63 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_09920 91346d72b561564273684e4cd9f85aa9 222 PRINTS PR01398 Isochorismatase signature 188 205 2.0E-34 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 A4R43_09920 91346d72b561564273684e4cd9f85aa9 222 PRINTS PR01398 Isochorismatase signature 61 78 2.0E-34 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 A4R43_09920 91346d72b561564273684e4cd9f85aa9 222 PRINTS PR01398 Isochorismatase signature 78 97 2.0E-34 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 A4R43_09920 91346d72b561564273684e4cd9f85aa9 222 PRINTS PR01398 Isochorismatase signature 2 14 2.0E-34 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 A4R43_09920 91346d72b561564273684e4cd9f85aa9 222 PRINTS PR01398 Isochorismatase signature 170 188 2.0E-34 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 A4R43_09920 91346d72b561564273684e4cd9f85aa9 222 Pfam PF00857 Isochorismatase family 32 206 5.6E-41 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4R43_09920 91346d72b561564273684e4cd9f85aa9 222 Gene3D G3DSA:3.40.50.850 1 209 1.3E-77 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_07565 92a0bdbacd75e08bba49f6e4926b6ead 328 Pfam PF14518 Iron-containing redox enzyme 133 305 3.2E-44 T 14-10-2018 A4R43_07565 92a0bdbacd75e08bba49f6e4926b6ead 328 SMART SM01236 165 270 1.8E-32 T 14-10-2018 A4R43_07565 92a0bdbacd75e08bba49f6e4926b6ead 328 SUPERFAMILY SSF48613 128 303 2.82E-10 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_07565 92a0bdbacd75e08bba49f6e4926b6ead 328 Gene3D G3DSA:1.20.910.10 118 322 1.8E-26 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4R43_28575 dc0f74271092122f30145eadbf71edc2 183 Pfam PF10517 Electron transfer DM13 78 181 3.7E-29 T 14-10-2018 IPR019545 DM13 domain A4R43_21545 c684f3d98ed7f9c74bc5c51eb84aa23d 391 SUPERFAMILY SSF103473 5 381 1.57E-57 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_21545 c684f3d98ed7f9c74bc5c51eb84aa23d 391 PRINTS PR01035 Tetracycline resistance protein signature 40 59 3.1E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_21545 c684f3d98ed7f9c74bc5c51eb84aa23d 391 PRINTS PR01035 Tetracycline resistance protein signature 71 95 3.1E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_21545 c684f3d98ed7f9c74bc5c51eb84aa23d 391 PRINTS PR01035 Tetracycline resistance protein signature 158 178 3.1E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_21545 c684f3d98ed7f9c74bc5c51eb84aa23d 391 PRINTS PR01035 Tetracycline resistance protein signature 98 119 3.1E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4R43_21545 c684f3d98ed7f9c74bc5c51eb84aa23d 391 Pfam PF07690 Major Facilitator Superfamily 8 317 5.6E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_21545 c684f3d98ed7f9c74bc5c51eb84aa23d 391 Gene3D G3DSA:1.20.1250.20 3 373 4.0E-46 T 14-10-2018 A4R43_16325 bed6152a2c720b62e598713126e4093d 357 Pfam PF00793 DAHP synthetase I family 50 346 2.8E-86 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4R43_16325 bed6152a2c720b62e598713126e4093d 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 12 357 6.7E-142 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4R43_16325 bed6152a2c720b62e598713126e4093d 357 SUPERFAMILY SSF51569 16 356 3.98E-121 T 14-10-2018 A4R43_16325 bed6152a2c720b62e598713126e4093d 357 Gene3D G3DSA:3.20.20.70 8 357 4.8E-141 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_16325 bed6152a2c720b62e598713126e4093d 357 PIRSF PIRSF001361 4 357 1.4E-147 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4R43_41375 7750b73bfa1d327decebe7a8293221cc 424 Pfam PF01882 Protein of unknown function DUF58 201 280 9.7E-20 T 14-10-2018 IPR002881 Domain of unknown function DUF58 A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 SUPERFAMILY SSF52172 2 176 7.21E-17 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 SMART SM00448 1 120 9.6E-7 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 Pfam PF00072 Response regulator receiver domain 4 108 6.7E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 197 2.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 SMART SM00421 148 205 8.7E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_33455 fa8f5a6d5d706a3842fe9cca55031e15 214 Gene3D G3DSA:3.40.50.12740 1 207 1.4E-43 T 14-10-2018 A4R43_16420 febb6a8c1d8fd47cad62dd92d8faf6da 328 Pfam PF13404 AsnC-type helix-turn-helix domain 5 44 8.6E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4R43_16420 febb6a8c1d8fd47cad62dd92d8faf6da 328 Gene3D G3DSA:1.10.10.10 5 49 2.1E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12640 0f48f623e5c557a064423064a52c6dd8 471 ProSitePatterns PS00455 Putative AMP-binding domain signature. 126 137 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_12640 0f48f623e5c557a064423064a52c6dd8 471 Gene3D G3DSA:3.30.300.30 363 467 4.6E-7 T 14-10-2018 A4R43_12640 0f48f623e5c557a064423064a52c6dd8 471 SUPERFAMILY SSF56801 3 457 1.13E-72 T 14-10-2018 A4R43_12640 0f48f623e5c557a064423064a52c6dd8 471 Gene3D G3DSA:3.40.50.12780 1 362 1.8E-62 T 14-10-2018 A4R43_12640 0f48f623e5c557a064423064a52c6dd8 471 Pfam PF00501 AMP-binding enzyme 7 362 8.4E-48 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 SMART SM00421 151 208 2.9E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 Gene3D G3DSA:3.40.50.2300 2 136 1.3E-5 T 14-10-2018 A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 SUPERFAMILY SSF46894 144 213 2.24E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 Gene3D G3DSA:1.10.10.10 143 216 9.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 SUPERFAMILY SSF52172 3 125 1.48E-5 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 3.6E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 3.6E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 3.6E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_38595 1167f8715654a5b792cab4e6abb099f5 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 3.6E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_01695 fd4d6db2116eb9a605e6d0c4fde2f095 645 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 302 1.6E-51 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_01695 fd4d6db2116eb9a605e6d0c4fde2f095 645 SUPERFAMILY SSF56281 328 625 1.37E-54 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_01695 fd4d6db2116eb9a605e6d0c4fde2f095 645 Pfam PF00753 Metallo-beta-lactamase superfamily 359 557 1.4E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_01695 fd4d6db2116eb9a605e6d0c4fde2f095 645 Gene3D G3DSA:3.90.850.10 5 303 1.0E-79 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_01695 fd4d6db2116eb9a605e6d0c4fde2f095 645 SMART SM00849 358 557 1.3E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_01695 fd4d6db2116eb9a605e6d0c4fde2f095 645 SUPERFAMILY SSF56529 71 303 1.15E-59 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_08365 171d79dcf2192160f986b18305ff0297 530 Gene3D G3DSA:3.60.110.10 222 502 3.1E-20 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_08365 171d79dcf2192160f986b18305ff0297 530 SUPERFAMILY SSF56317 227 494 6.28E-42 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4R43_08365 171d79dcf2192160f986b18305ff0297 530 Pfam PF00795 Carbon-nitrogen hydrolase 295 469 7.0E-23 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4R43_08365 171d79dcf2192160f986b18305ff0297 530 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 22 498 16.736 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4R43_08365 171d79dcf2192160f986b18305ff0297 530 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 75 460 1.9E-76 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4R43_01530 f9adf7b79db2bd4a72e9bbfbc92f7705 498 Pfam PF00916 Sulfate permease family 14 381 2.1E-58 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4R43_21735 02f19e9085d2d78c3b997924a0e60356 413 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 14 225 3.0E-43 T 14-10-2018 A4R43_21735 02f19e9085d2d78c3b997924a0e60356 413 TIGRFAM TIGR04364 methyltran_FxLD: methyltransferase, FxLD system 11 412 4.3E-126 T 14-10-2018 IPR027573 Methyltransferase, FxLD system A4R43_21735 02f19e9085d2d78c3b997924a0e60356 413 SUPERFAMILY SSF53335 8 226 9.33E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_21735 02f19e9085d2d78c3b997924a0e60356 413 Gene3D G3DSA:3.40.50.150 2 231 8.2E-63 T 14-10-2018 A4R43_16615 cb0b793bfcc7e48f822f080eb728bf43 397 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 302 2.9E-68 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16615 cb0b793bfcc7e48f822f080eb728bf43 397 Pfam PF02470 MlaD protein 38 112 6.5E-14 T 14-10-2018 IPR003399 Mce/MlaD A4R43_34330 d974efff63e7ef4971973ed77398a943 190 Pfam PF04542 Sigma-70 region 2 26 98 1.4E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_34330 d974efff63e7ef4971973ed77398a943 190 Gene3D G3DSA:1.10.1740.10 7 96 2.3E-14 T 14-10-2018 A4R43_34330 d974efff63e7ef4971973ed77398a943 190 Gene3D G3DSA:1.10.10.10 126 188 1.7E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_34330 d974efff63e7ef4971973ed77398a943 190 SUPERFAMILY SSF88659 113 185 5.05E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_34330 d974efff63e7ef4971973ed77398a943 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 184 2.5E-27 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_34330 d974efff63e7ef4971973ed77398a943 190 SUPERFAMILY SSF88946 9 111 2.83E-19 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_34330 d974efff63e7ef4971973ed77398a943 190 Pfam PF08281 Sigma-70, region 4 129 180 8.2E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_10150 51056a91cb0d560269ac5a4946932ba5 474 Gene3D G3DSA:3.90.1150.10 101 465 9.5E-82 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_10150 51056a91cb0d560269ac5a4946932ba5 474 SMART SM00345 9 66 1.7E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_10150 51056a91cb0d560269ac5a4946932ba5 474 Pfam PF00155 Aminotransferase class I and II 123 446 1.9E-18 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_10150 51056a91cb0d560269ac5a4946932ba5 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 1.0E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_10150 51056a91cb0d560269ac5a4946932ba5 474 Gene3D G3DSA:1.10.10.10 3 74 2.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10150 51056a91cb0d560269ac5a4946932ba5 474 Gene3D G3DSA:3.40.640.10 138 360 9.5E-82 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_10150 51056a91cb0d560269ac5a4946932ba5 474 SUPERFAMILY SSF53383 93 465 9.99E-73 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_10150 51056a91cb0d560269ac5a4946932ba5 474 SUPERFAMILY SSF46785 6 70 3.18E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38365 bfe64bbe83365450116b6cc414af8758 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 11 158 3.6E-22 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4R43_38365 bfe64bbe83365450116b6cc414af8758 293 Gene3D G3DSA:3.40.50.720 8 162 7.4E-40 T 14-10-2018 A4R43_38365 bfe64bbe83365450116b6cc414af8758 293 SUPERFAMILY SSF51735 9 163 1.15E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38365 bfe64bbe83365450116b6cc414af8758 293 PIRSF PIRSF000103 1 293 4.3E-41 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4R43_38365 bfe64bbe83365450116b6cc414af8758 293 Gene3D G3DSA:1.10.1040.10 164 292 1.2E-42 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_39005 54c1710fc9d22644537bdced985f869e 612 SUPERFAMILY SSF52540 24 270 1.48E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39005 54c1710fc9d22644537bdced985f869e 612 Gene3D G3DSA:3.40.50.300 109 278 1.9E-8 T 14-10-2018 A4R43_39005 54c1710fc9d22644537bdced985f869e 612 Gene3D G3DSA:3.40.50.300 19 98 4.2E-9 T 14-10-2018 A4R43_39005 54c1710fc9d22644537bdced985f869e 612 Pfam PF00350 Dynamin family 43 195 1.7E-10 T 14-10-2018 IPR022812 Dynamin superfamily A4R43_39145 30fc2fe006f438b4dc988222468059f3 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 325 5.6E-46 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_35170 27120fadd11ebf7820e73da6931a0f88 265 SUPERFAMILY SSF54637 3 104 1.9E-16 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_35170 27120fadd11ebf7820e73da6931a0f88 265 Gene3D G3DSA:3.10.129.90 1 264 1.3E-75 T 14-10-2018 A4R43_35170 27120fadd11ebf7820e73da6931a0f88 265 SUPERFAMILY SSF54637 149 264 2.31E-6 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_35170 27120fadd11ebf7820e73da6931a0f88 265 Pfam PF13622 Thioesterase-like superfamily 23 261 2.8E-41 T 14-10-2018 A4R43_19010 e0125a01e98a3386a001b31d1d764d0c 269 SUPERFAMILY SSF51658 3 265 1.7E-52 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_19010 e0125a01e98a3386a001b31d1d764d0c 269 Pfam PF01261 Xylose isomerase-like TIM barrel 24 219 1.0E-25 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_19010 e0125a01e98a3386a001b31d1d764d0c 269 Gene3D G3DSA:3.20.20.150 1 268 3.4E-61 T 14-10-2018 A4R43_26380 14989484747bb74f83e929582a299ba6 276 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 52 276 4.4E-74 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 A4R43_26380 14989484747bb74f83e929582a299ba6 276 PIRSF PIRSF037834 34 276 3.8E-87 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 A4R43_26380 14989484747bb74f83e929582a299ba6 276 SUPERFAMILY SSF47240 45 270 7.7E-65 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_26380 14989484747bb74f83e929582a299ba6 276 Gene3D G3DSA:1.20.1260.10 36 276 1.3E-88 T 14-10-2018 IPR012347 Ferritin-like A4R43_26380 14989484747bb74f83e929582a299ba6 276 Pfam PF05138 Phenylacetic acid catabolic protein 40 276 9.3E-79 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 A4R43_23575 e111ac4326f7e2dd4f4097027748d5b4 270 Pfam PF16158 Ig-like domain from next to BRCA1 gene 165 253 6.6E-18 T 14-10-2018 IPR032350 Next to BRCA1, central domain A4R43_23575 e111ac4326f7e2dd4f4097027748d5b4 270 Gene3D G3DSA:2.60.40.10 152 259 2.8E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_11130 baa525fe38da005ebdf8de81f9d9d13b 537 Pfam PF08386 TAP-like protein 424 521 2.3E-17 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_11130 baa525fe38da005ebdf8de81f9d9d13b 537 Pfam PF00561 alpha/beta hydrolase fold 101 260 1.1E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_11130 baa525fe38da005ebdf8de81f9d9d13b 537 SUPERFAMILY SSF53474 98 498 1.49E-25 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14055 26c9ace76ce0dd0eb401d58acaa786ee 162 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 4 146 31.617 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 A4R43_14055 26c9ace76ce0dd0eb401d58acaa786ee 162 TIGRFAM TIGR00576 dut: dUTP diphosphatase 7 145 5.9E-49 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 A4R43_14055 26c9ace76ce0dd0eb401d58acaa786ee 162 SUPERFAMILY SSF51283 6 145 1.83E-47 T 14-10-2018 IPR036157 dUTPase-like superfamily A4R43_14055 26c9ace76ce0dd0eb401d58acaa786ee 162 Pfam PF00692 dUTPase 16 145 1.1E-31 T 14-10-2018 IPR029054 dUTPase-like A4R43_14055 26c9ace76ce0dd0eb401d58acaa786ee 162 Gene3D G3DSA:2.70.40.10 2 150 4.9E-52 T 14-10-2018 IPR036157 dUTPase-like superfamily A4R43_36745 97c487362cff5052b8286439019df0e9 110 Gene3D G3DSA:1.20.5.340 15 109 2.2E-6 T 14-10-2018 A4R43_09735 b0277999559077ede6ed19fcaa8fd529 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 3.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_09735 b0277999559077ede6ed19fcaa8fd529 190 SUPERFAMILY SSF46689 4 74 1.44E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_09735 b0277999559077ede6ed19fcaa8fd529 190 Gene3D G3DSA:1.10.357.10 1 188 1.4E-13 T 14-10-2018 A4R43_26700 a72ac6eac777be8f1781ad66e9c141e2 254 Pfam PF12697 Alpha/beta hydrolase family 17 240 7.9E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_26700 a72ac6eac777be8f1781ad66e9c141e2 254 SUPERFAMILY SSF53474 7 248 6.32E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_26700 a72ac6eac777be8f1781ad66e9c141e2 254 Gene3D G3DSA:3.40.50.1820 3 250 1.9E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_04555 be654507112c00b22ee9426c5a0de1df 402 Gene3D G3DSA:3.60.10.10 32 400 1.0E-15 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_04555 be654507112c00b22ee9426c5a0de1df 402 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 38 389 2.1E-23 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4R43_04555 be654507112c00b22ee9426c5a0de1df 402 SUPERFAMILY SSF56219 33 396 3.02E-17 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_30695 caf6db70e37c27e79db263172edfa24f 195 Pfam PF03551 Transcriptional regulator PadR-like family 16 80 4.4E-7 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_30695 caf6db70e37c27e79db263172edfa24f 195 SUPERFAMILY SSF46785 4 172 8.49E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_30695 caf6db70e37c27e79db263172edfa24f 195 Gene3D G3DSA:1.10.10.10 3 88 1.9E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35845 7c6b72568a3adcc5c3235e3e94f378bc 111 Pfam PF16170 Domain of unknown function (DUF4873) 9 99 4.2E-36 T 14-10-2018 IPR032371 Domain of unknown function DUF4873 A4R43_29645 520e32c2144bcb3f47032943aa259a60 237 SMART SM00858 71 134 0.0021 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 SMART SM00883 4 96 1.6E-53 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 Pfam PF00166 Chaperonin 10 Kd subunit 4 96 7.9E-36 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 Gene3D G3DSA:2.30.33.40 1 97 1.8E-38 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 Hamap MF_00580 10 kDa chaperonin [groS]. 4 97 25.959 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 SUPERFAMILY SSF50129 3 97 9.04E-35 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 PRINTS PR00297 10kDa chaperonin signature 62 74 7.1E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 PRINTS PR00297 10kDa chaperonin signature 5 20 7.1E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 PRINTS PR00297 10kDa chaperonin signature 83 96 7.1E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_34290 0fc8f8054d09cf37da15b826273e7948 97 PRINTS PR00297 10kDa chaperonin signature 27 48 7.1E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4R43_20940 67f07bcded200805f54d4fb78458f917 211 Pfam PF03029 Conserved hypothetical ATP binding protein 24 190 2.7E-22 T 14-10-2018 IPR004130 GPN-loop GTPase A4R43_20940 67f07bcded200805f54d4fb78458f917 211 Gene3D G3DSA:3.40.50.300 15 197 1.7E-17 T 14-10-2018 A4R43_20940 67f07bcded200805f54d4fb78458f917 211 SUPERFAMILY SSF52540 19 192 9.59E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_34315 cb7b7a563abd9f3eae74447eab939b52 340 Gene3D G3DSA:3.40.50.280 215 329 5.3E-6 T 14-10-2018 A4R43_34315 cb7b7a563abd9f3eae74447eab939b52 340 SMART SM00422 14 83 4.6E-4 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_34315 cb7b7a563abd9f3eae74447eab939b52 340 SUPERFAMILY SSF46955 16 81 2.88E-10 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_34315 cb7b7a563abd9f3eae74447eab939b52 340 Gene3D G3DSA:1.10.1660.10 10 83 4.6E-17 T 14-10-2018 A4R43_34315 cb7b7a563abd9f3eae74447eab939b52 340 Pfam PF13411 MerR HTH family regulatory protein 17 79 2.0E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_37655 66f647a44d65ad346353e41d7228012e 221 Gene3D G3DSA:3.40.50.2300 1 118 2.2E-33 T 14-10-2018 A4R43_37655 66f647a44d65ad346353e41d7228012e 221 SMART SM00448 1 112 7.3E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_37655 66f647a44d65ad346353e41d7228012e 221 SUPERFAMILY SSF52172 1 175 3.32E-36 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_37655 66f647a44d65ad346353e41d7228012e 221 SMART SM00862 145 216 8.7E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37655 66f647a44d65ad346353e41d7228012e 221 Gene3D G3DSA:1.10.10.10 119 218 3.6E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37655 66f647a44d65ad346353e41d7228012e 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.4E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37655 66f647a44d65ad346353e41d7228012e 221 Pfam PF00072 Response regulator receiver domain 3 112 2.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_02680 06b44918ef1a918cc4dccc138de0d302 340 Pfam PF00535 Glycosyl transferase family 2 48 166 8.5E-14 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_02680 06b44918ef1a918cc4dccc138de0d302 340 SUPERFAMILY SSF53448 47 286 1.73E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_02680 06b44918ef1a918cc4dccc138de0d302 340 Gene3D G3DSA:3.90.550.10 8 330 3.3E-103 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_36945 6ef85b87b2bc47554b266ab4b1ae8036 155 Pfam PF14108 Domain of unknown function (DUF4281) 5 128 6.7E-39 T 14-10-2018 IPR025461 ABA DEFICIENT 4-like A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 Gene3D G3DSA:1.10.150.240 28 86 1.1E-47 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 Gene3D G3DSA:3.40.50.1000 16 208 1.1E-47 T 14-10-2018 IPR023214 HAD superfamily A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 5.6E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 13 24 5.6E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 171 5.6E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 5.6E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 105 183 4.7E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 83 187 2.6E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 SUPERFAMILY SSF56784 15 217 2.67E-52 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 TIGRFAM TIGR01454 AHBA_synth_RP: AHBA synthesis associated protein 16 221 1.2E-106 T 14-10-2018 IPR006351 3-amino-5-hydroxybenzoic acid synthesis-related A4R43_38535 722a2d1e4551e126e2b4072a77160e4e 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 188 6.0E-33 T 14-10-2018 A4R43_39560 14f67705c249da68c0d5244c81ade559 268 SMART SM00530 5 78 8.2E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_39560 14f67705c249da68c0d5244c81ade559 268 SUPERFAMILY SSF47413 25 77 1.33E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_39560 14f67705c249da68c0d5244c81ade559 268 Gene3D G3DSA:3.30.450.180 104 264 1.7E-9 T 14-10-2018 A4R43_39560 14f67705c249da68c0d5244c81ade559 268 Pfam PF13560 Helix-turn-helix domain 2 81 2.7E-19 T 14-10-2018 A4R43_39560 14f67705c249da68c0d5244c81ade559 268 Gene3D G3DSA:1.10.260.40 21 92 3.1E-8 T 14-10-2018 A4R43_02700 9f913b66c051fc451bfff9a30852781b 503 Pfam PF00561 alpha/beta hydrolase fold 82 449 1.4E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02700 9f913b66c051fc451bfff9a30852781b 503 SUPERFAMILY SSF53474 81 464 7.21E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_39930 a40d7d07d1aa8d30948abfb4100bae9e 374 SUPERFAMILY SSF51905 5 352 3.05E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_39930 a40d7d07d1aa8d30948abfb4100bae9e 374 Pfam PF01494 FAD binding domain 4 342 6.2E-32 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_39930 a40d7d07d1aa8d30948abfb4100bae9e 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.5E-22 T 14-10-2018 A4R43_39930 a40d7d07d1aa8d30948abfb4100bae9e 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 6.5E-22 T 14-10-2018 A4R43_39930 a40d7d07d1aa8d30948abfb4100bae9e 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 6.5E-22 T 14-10-2018 A4R43_39930 a40d7d07d1aa8d30948abfb4100bae9e 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 328 344 6.5E-22 T 14-10-2018 A4R43_39930 a40d7d07d1aa8d30948abfb4100bae9e 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 6.5E-22 T 14-10-2018 A4R43_39930 a40d7d07d1aa8d30948abfb4100bae9e 374 Gene3D G3DSA:3.50.50.60 4 358 3.0E-71 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_21445 fba171571fbf051762b568310112af02 336 Pfam PF00487 Fatty acid desaturase 57 281 9.8E-19 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_21445 fba171571fbf051762b568310112af02 336 PRINTS PR00075 Fatty acid desaturase family 1 signature 216 237 3.1E-17 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_21445 fba171571fbf051762b568310112af02 336 PRINTS PR00075 Fatty acid desaturase family 1 signature 56 78 3.1E-17 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_21445 fba171571fbf051762b568310112af02 336 PRINTS PR00075 Fatty acid desaturase family 1 signature 79 99 3.1E-17 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_21445 fba171571fbf051762b568310112af02 336 PRINTS PR00075 Fatty acid desaturase family 1 signature 259 273 3.1E-17 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_35615 5152d46df4a71e9ccef18f15da306ec7 186 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 11 184 3.0E-78 T 14-10-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 A4R43_35615 5152d46df4a71e9ccef18f15da306ec7 186 Gene3D G3DSA:1.10.340.30 9 186 6.5E-74 T 14-10-2018 A4R43_35615 5152d46df4a71e9ccef18f15da306ec7 186 SUPERFAMILY SSF48150 10 185 6.67E-69 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4R43_35615 5152d46df4a71e9ccef18f15da306ec7 186 Pfam PF03352 Methyladenine glycosylase 14 184 6.2E-69 T 14-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 A4R43_24665 dc71e7aa0dcd96453d9d4d72988f3559 143 Pfam PF09828 Chromate resistance exported protein 3 131 2.5E-49 T 14-10-2018 IPR018634 Chromate resistance exported protein A4R43_05950 bc255aee036a2dbeb880d721df9e3c56 318 Pfam PF07859 alpha/beta hydrolase fold 90 291 2.6E-51 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_05950 bc255aee036a2dbeb880d721df9e3c56 318 Gene3D G3DSA:3.40.50.1820 7 317 3.7E-77 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_05950 bc255aee036a2dbeb880d721df9e3c56 318 SUPERFAMILY SSF53474 58 317 4.89E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_33100 0892e4a3fa6dfb7e0d6a1c88d49f77bb 286 Gene3D G3DSA:1.10.10.1590 49 118 1.2E-21 T 14-10-2018 A4R43_33100 0892e4a3fa6dfb7e0d6a1c88d49f77bb 286 SUPERFAMILY SSF52833 50 217 4.36E-42 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_33100 0892e4a3fa6dfb7e0d6a1c88d49f77bb 286 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 58 209 1.2E-43 T 14-10-2018 A4R43_33100 0892e4a3fa6dfb7e0d6a1c88d49f77bb 286 Gene3D G3DSA:3.40.30.10 119 225 1.7E-20 T 14-10-2018 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 SUPERFAMILY SSF53671 2 305 2.23E-102 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 140 1.7E-47 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 Gene3D G3DSA:3.40.50.1370 130 290 8.0E-120 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 45 52 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 220 230 3.4E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 43 57 3.4E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 116 130 3.4E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 76 89 3.4E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 282 293 3.4E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 Gene3D G3DSA:3.40.50.1370 9 300 8.0E-120 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 301 2.7E-53 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 303 5.1E-117 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 304 77.234 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 8.9E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 45 64 8.9E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 8.9E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_14310 d723079c9d274876425b12e54fa7c90d 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 8.9E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4R43_16305 a7d538461d6f611fbbe2b98838491284 221 PIRSF PIRSF028451 2 217 3.9E-35 T 14-10-2018 IPR015996 Uncharacterised conserved protein UCP028451 A4R43_16305 a7d538461d6f611fbbe2b98838491284 221 Pfam PF09365 Conserved hypothetical protein (DUF2461) 10 208 6.3E-50 T 14-10-2018 IPR012808 Conserved hypothetical protein CHP02453 A4R43_16305 a7d538461d6f611fbbe2b98838491284 221 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 7 212 6.6E-38 T 14-10-2018 IPR012808 Conserved hypothetical protein CHP02453 A4R43_21270 be92ceda2c3601475ecfda4ba49fb132 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.9E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21270 be92ceda2c3601475ecfda4ba49fb132 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.9E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21270 be92ceda2c3601475ecfda4ba49fb132 199 Gene3D G3DSA:1.10.357.10 1 198 3.0E-37 T 14-10-2018 A4R43_21270 be92ceda2c3601475ecfda4ba49fb132 199 SUPERFAMILY SSF46689 2 82 1.39E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21270 be92ceda2c3601475ecfda4ba49fb132 199 SUPERFAMILY SSF48498 86 190 8.9E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_21270 be92ceda2c3601475ecfda4ba49fb132 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.9E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 SUPERFAMILY SSF51905 2 344 4.2E-65 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 Gene3D G3DSA:3.50.50.60 1 178 1.2E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 315 331 7.7E-48 T 14-10-2018 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 315 7.7E-48 T 14-10-2018 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.7E-48 T 14-10-2018 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 141 156 7.7E-48 T 14-10-2018 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 295 7.7E-48 T 14-10-2018 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 264 279 7.7E-48 T 14-10-2018 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 Gene3D G3DSA:3.40.30.120 377 468 3.0E-29 T 14-10-2018 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 Pfam PF01494 FAD binding domain 2 329 5.7E-87 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 Gene3D G3DSA:3.50.50.60 250 376 3.1E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_00220 78b5c5b2a8783df0dad7cf2813fa7b11 470 Gene3D G3DSA:3.30.70.2450 179 249 7.7E-14 T 14-10-2018 A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 SUPERFAMILY SSF52540 264 474 2.41E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 Pfam PF00005 ABC transporter 267 420 1.0E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 Pfam PF00005 ABC transporter 17 167 2.8E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 ProSitePatterns PS00211 ABC transporters family signature. 393 407 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 Gene3D G3DSA:3.40.50.300 253 489 8.9E-46 T 14-10-2018 A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 SMART SM00382 275 469 3.1E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 SMART SM00382 26 224 7.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 SUPERFAMILY SSF52540 3 223 4.07E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_22600 46edf9838e40ea3780e5a0e3e18936d0 492 Gene3D G3DSA:3.40.50.300 1 242 2.8E-54 T 14-10-2018 A4R43_22820 4d52de0531f8f6adddbfbcde9cdfeea9 466 Gene3D G3DSA:1.10.45.10 421 460 2.2E-11 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4R43_22820 4d52de0531f8f6adddbfbcde9cdfeea9 466 Pfam PF02913 FAD linked oxidases, C-terminal domain 223 458 1.2E-51 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4R43_22820 4d52de0531f8f6adddbfbcde9cdfeea9 466 Gene3D G3DSA:3.30.70.2740 344 420 3.2E-12 T 14-10-2018 A4R43_22820 4d52de0531f8f6adddbfbcde9cdfeea9 466 SUPERFAMILY SSF55103 224 462 2.45E-51 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4R43_22820 4d52de0531f8f6adddbfbcde9cdfeea9 466 Gene3D G3DSA:3.30.465.40 11 228 2.3E-64 T 14-10-2018 A4R43_22820 4d52de0531f8f6adddbfbcde9cdfeea9 466 SUPERFAMILY SSF56176 9 218 1.64E-61 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4R43_22820 4d52de0531f8f6adddbfbcde9cdfeea9 466 Pfam PF01565 FAD binding domain 45 183 2.9E-38 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4R43_27875 7f364021b5cdc7cdcc99a6decfd99972 254 Pfam PF01925 Sulfite exporter TauE/SafE 9 250 2.1E-41 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A4R43_00915 654576261ac28ca9341a24a0fb53211a 494 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 17 435 8.7E-127 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A4R43_03170 e3fa2ba0337ee9ad990c70fdb4a0550b 138 Gene3D G3DSA:3.10.450.50 2 119 6.2E-23 T 14-10-2018 A4R43_03170 e3fa2ba0337ee9ad990c70fdb4a0550b 138 Pfam PF12680 SnoaL-like domain 7 106 1.8E-17 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_03170 e3fa2ba0337ee9ad990c70fdb4a0550b 138 SUPERFAMILY SSF54427 4 118 4.93E-24 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_05295 3615c48cb251043e750db545920d96bb 518 Pfam PF01039 Carboxyl transferase domain 30 495 4.1E-69 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4R43_05295 3615c48cb251043e750db545920d96bb 518 SUPERFAMILY SSF52096 235 504 7.46E-49 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_05295 3615c48cb251043e750db545920d96bb 518 Gene3D G3DSA:3.90.226.10 4 263 7.2E-61 T 14-10-2018 A4R43_05295 3615c48cb251043e750db545920d96bb 518 Gene3D G3DSA:3.90.226.10 264 508 4.1E-54 T 14-10-2018 A4R43_05295 3615c48cb251043e750db545920d96bb 518 SUPERFAMILY SSF52096 5 260 3.8E-48 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_02670 4a614041b5632c716070427621b6992e 367 SUPERFAMILY SSF51735 163 299 8.54E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_02670 4a614041b5632c716070427621b6992e 367 Pfam PF00107 Zinc-binding dehydrogenase 179 270 6.4E-13 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4R43_02670 4a614041b5632c716070427621b6992e 367 SUPERFAMILY SSF50129 16 134 1.04E-5 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_02670 4a614041b5632c716070427621b6992e 367 Gene3D G3DSA:3.90.180.10 95 346 2.7E-28 T 14-10-2018 A4R43_02670 4a614041b5632c716070427621b6992e 367 Gene3D G3DSA:3.40.50.720 146 306 2.7E-28 T 14-10-2018 A4R43_11400 4106280463d65a479c71b9feac532116 261 SUPERFAMILY SSF56529 4 260 1.03E-80 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_11400 4106280463d65a479c71b9feac532116 261 Gene3D G3DSA:3.90.850.10 3 260 1.2E-88 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_11400 4106280463d65a479c71b9feac532116 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 80 258 2.7E-17 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_04565 674a69548c1823cbab8b79f016f103a1 272 Gene3D G3DSA:3.40.710.10 2 270 4.8E-75 T 14-10-2018 A4R43_04565 674a69548c1823cbab8b79f016f103a1 272 Pfam PF00144 Beta-lactamase 15 251 3.5E-34 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_04565 674a69548c1823cbab8b79f016f103a1 272 SUPERFAMILY SSF56601 6 265 2.09E-55 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_36755 cffb18cf89577c729efd37dd00c546ea 141 SUPERFAMILY SSF47413 9 77 1.48E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_36755 cffb18cf89577c729efd37dd00c546ea 141 Gene3D G3DSA:1.10.260.40 1 76 1.6E-7 T 14-10-2018 A4R43_38905 5b65cd004b3d33c4b258905146ddfd3b 254 SUPERFAMILY SSF142823 10 248 1.57E-40 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A4R43_38905 5b65cd004b3d33c4b258905146ddfd3b 254 Gene3D G3DSA:3.90.1560.10 20 252 1.3E-34 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A4R43_38905 5b65cd004b3d33c4b258905146ddfd3b 254 Pfam PF04029 2-phosphosulpholactate phosphatase 29 245 8.0E-21 T 14-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 Gene3D G3DSA:1.10.10.10 85 162 5.2E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 Gene3D G3DSA:1.10.1740.10 3 78 3.1E-10 T 14-10-2018 A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 SUPERFAMILY SSF54427 170 276 2.36E-8 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 SUPERFAMILY SSF88659 99 159 3.18E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 159 4.0E-17 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 Pfam PF08281 Sigma-70, region 4 107 157 2.8E-7 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 Gene3D G3DSA:3.10.450.50 163 278 1.1E-5 T 14-10-2018 A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 SUPERFAMILY SSF88946 2 91 1.18E-16 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_06540 647ca82ec77b238a60afd74d0d316716 285 Pfam PF04542 Sigma-70 region 2 11 75 3.8E-14 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_24600 cfcacdd041bac09be82c7d5cfa4a65c4 161 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 156 1.0E-23 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A4R43_24600 cfcacdd041bac09be82c7d5cfa4a65c4 161 Gene3D G3DSA:3.30.479.10 1 160 3.6E-24 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A4R43_24600 cfcacdd041bac09be82c7d5cfa4a65c4 161 SUPERFAMILY SSF55620 3 157 3.56E-25 T 14-10-2018 A4R43_16910 427ee48539a684b1b8fe92378527aa09 280 SUPERFAMILY SSF53850 8 260 3.34E-56 T 14-10-2018 A4R43_16910 427ee48539a684b1b8fe92378527aa09 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 260 2.6E-50 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_16910 427ee48539a684b1b8fe92378527aa09 280 SMART SM00062 43 267 6.4E-65 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_16910 427ee48539a684b1b8fe92378527aa09 280 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 66 79 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site A4R43_16910 427ee48539a684b1b8fe92378527aa09 280 Gene3D G3DSA:3.40.190.10 133 225 1.6E-64 T 14-10-2018 A4R43_16910 427ee48539a684b1b8fe92378527aa09 280 Gene3D G3DSA:3.40.190.10 37 259 1.6E-64 T 14-10-2018 A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 SUPERFAMILY SSF56112 18 332 3.24E-68 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 Gene3D G3DSA:1.10.510.10 24 288 3.5E-65 T 14-10-2018 A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 SMART SM00220 30 284 5.5E-59 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 146 158 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 PRINTS PR01217 Proline rich extensin signature 306 322 5.3E-10 T 14-10-2018 A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 PRINTS PR01217 Proline rich extensin signature 279 300 5.3E-10 T 14-10-2018 A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 PRINTS PR01217 Proline rich extensin signature 393 418 5.3E-10 T 14-10-2018 A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 PRINTS PR01217 Proline rich extensin signature 333 350 5.3E-10 T 14-10-2018 A4R43_17950 cbee923c305844586291cd2a1c0cfa0a 482 Pfam PF00069 Protein kinase domain 30 272 1.8E-45 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_32355 1ce052123931bc7a3c5de25b88687482 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32355 1ce052123931bc7a3c5de25b88687482 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32355 1ce052123931bc7a3c5de25b88687482 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_32355 1ce052123931bc7a3c5de25b88687482 202 Gene3D G3DSA:1.10.357.10 5 184 1.3E-27 T 14-10-2018 A4R43_32355 1ce052123931bc7a3c5de25b88687482 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.1E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32355 1ce052123931bc7a3c5de25b88687482 202 SUPERFAMILY SSF46689 6 87 1.31E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31920 d297f9e51425a3a0b42c1c303dcc9b74 71 Pfam PF04149 Domain of unknown function (DUF397) 9 62 2.0E-20 T 14-10-2018 IPR007278 Domain of unknown function DUF397 A4R43_03425 2af1198a2236f8ea0e211018ab4f4017 210 SUPERFAMILY SSF53335 10 191 1.07E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_03425 2af1198a2236f8ea0e211018ab4f4017 210 Gene3D G3DSA:3.40.50.150 7 208 2.1E-49 T 14-10-2018 A4R43_03425 2af1198a2236f8ea0e211018ab4f4017 210 Pfam PF13649 Methyltransferase domain 51 141 5.8E-18 T 14-10-2018 A4R43_08300 114ecc3e87946fd454b72a7268986b22 296 SUPERFAMILY SSF110849 4 84 2.44E-9 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A4R43_08300 114ecc3e87946fd454b72a7268986b22 296 Pfam PF02195 ParB-like nuclease domain 9 83 3.9E-10 T 14-10-2018 IPR003115 ParB/Sulfiredoxin A4R43_08300 114ecc3e87946fd454b72a7268986b22 296 SMART SM00470 1 84 3.4E-8 T 14-10-2018 IPR003115 ParB/Sulfiredoxin A4R43_24825 cd9a94d464e0652a9d54f125925c872c 401 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 355 8.6E-25 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_24825 cd9a94d464e0652a9d54f125925c872c 401 Pfam PF01548 Transposase 9 163 4.6E-42 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_23015 cd9a94d464e0652a9d54f125925c872c 401 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 355 8.6E-25 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_23015 cd9a94d464e0652a9d54f125925c872c 401 Pfam PF01548 Transposase 9 163 4.6E-42 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_17230 8b875f62b42e847e22afb91d42d592d0 414 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 21 403 4.7E-185 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4R43_17230 8b875f62b42e847e22afb91d42d592d0 414 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 67 392 1.0E-51 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_17230 8b875f62b42e847e22afb91d42d592d0 414 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 16 405 51.515 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4R43_17230 8b875f62b42e847e22afb91d42d592d0 414 Gene3D G3DSA:3.40.50.1100 68 398 7.9E-183 T 14-10-2018 A4R43_17230 8b875f62b42e847e22afb91d42d592d0 414 Gene3D G3DSA:3.40.50.1100 24 220 7.9E-183 T 14-10-2018 A4R43_17230 8b875f62b42e847e22afb91d42d592d0 414 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 95 109 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4R43_17230 8b875f62b42e847e22afb91d42d592d0 414 PIRSF PIRSF001413 1 410 6.7E-159 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4R43_17230 8b875f62b42e847e22afb91d42d592d0 414 SUPERFAMILY SSF53686 17 404 2.36E-146 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_09495 ee21a54541d7ba384fa7e7884d949ad8 319 Pfam PF03631 Virulence factor BrkB 36 291 4.8E-66 T 14-10-2018 IPR017039 Virulence factor BrkB A4R43_09495 ee21a54541d7ba384fa7e7884d949ad8 319 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 29 289 8.6E-33 T 14-10-2018 IPR017039 Virulence factor BrkB A4R43_09495 ee21a54541d7ba384fa7e7884d949ad8 319 PIRSF PIRSF035875 11 313 9.6E-85 T 14-10-2018 IPR017039 Virulence factor BrkB A4R43_18475 846ccec1199b23397b38d65414540eb1 246 Pfam PF02517 CAAX protease self-immunity 148 236 2.2E-12 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A4R43_10300 936f910efb8ba3e8b8e732a9ebde7ad7 174 Pfam PF12840 Helix-turn-helix domain 5 60 1.9E-13 T 14-10-2018 A4R43_10300 936f910efb8ba3e8b8e732a9ebde7ad7 174 Gene3D G3DSA:1.10.10.10 1 73 5.3E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_10300 936f910efb8ba3e8b8e732a9ebde7ad7 174 SMART SM00418 2 80 1.3E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_10300 936f910efb8ba3e8b8e732a9ebde7ad7 174 SUPERFAMILY SSF46785 3 76 5.56E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_10300 936f910efb8ba3e8b8e732a9ebde7ad7 174 Gene3D G3DSA:1.20.1270.400 76 167 6.4E-22 T 14-10-2018 A4R43_38885 8dae2696dfc2b0557074265ad2f63dd2 207 Gene3D G3DSA:3.40.30.10 1 205 3.7E-72 T 14-10-2018 A4R43_38885 8dae2696dfc2b0557074265ad2f63dd2 207 SUPERFAMILY SSF52833 8 176 2.81E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_38885 8dae2696dfc2b0557074265ad2f63dd2 207 Pfam PF01323 DSBA-like thioredoxin domain 8 163 8.3E-9 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 A4R43_39590 090ad294ead80592100db525c1b63441 77 Gene3D G3DSA:3.40.50.1010 1 71 5.6E-9 T 14-10-2018 A4R43_39590 090ad294ead80592100db525c1b63441 77 SUPERFAMILY SSF88723 3 65 3.01E-8 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_35410 a74c537c7aeef368d979360d015d0581 529 Gene3D G3DSA:1.10.260.150 73 380 7.6E-64 T 14-10-2018 A4R43_35410 a74c537c7aeef368d979360d015d0581 529 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 118 291 1.0E-32 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_35410 a74c537c7aeef368d979360d015d0581 529 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 118 291 6.3E-39 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_35410 a74c537c7aeef368d979360d015d0581 529 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 395 479 1.2E-11 T 14-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4R43_06190 20d4acfe0870b953d6fb0fe0911d27c1 165 Gene3D G3DSA:3.30.530.20 3 159 4.4E-42 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_06190 20d4acfe0870b953d6fb0fe0911d27c1 165 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 131 1.1E-19 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_06190 20d4acfe0870b953d6fb0fe0911d27c1 165 SUPERFAMILY SSF55961 4 155 1.96E-21 T 14-10-2018 A4R43_09310 c1f044bdba32633fe37c503f556d9471 344 Gene3D G3DSA:1.10.600.10 13 344 2.1E-102 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_09310 c1f044bdba32633fe37c503f556d9471 344 SUPERFAMILY SSF48576 40 343 1.25E-76 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_09310 c1f044bdba32633fe37c503f556d9471 344 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 222 234 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4R43_09310 c1f044bdba32633fe37c503f556d9471 344 Pfam PF00348 Polyprenyl synthetase 59 294 2.8E-53 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A4R43_09310 c1f044bdba32633fe37c503f556d9471 344 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 97 111 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4R43_30030 8010dd015dacde6d3cf38984c4f683be 478 Pfam PF08388 Group II intron, maturase-specific domain 359 437 2.3E-20 T 14-10-2018 IPR013597 Group II intron, maturase-specific A4R43_30030 8010dd015dacde6d3cf38984c4f683be 478 SUPERFAMILY SSF56672 64 431 1.78E-38 T 14-10-2018 A4R43_30030 8010dd015dacde6d3cf38984c4f683be 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 424 4.4E-107 T 14-10-2018 IPR030931 Group II intron reverse transcriptase/maturase A4R43_30030 8010dd015dacde6d3cf38984c4f683be 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 108 336 1.1E-37 T 14-10-2018 IPR000477 Reverse transcriptase domain A4R43_39880 5dbfde7e1c5205e6d3c5609d852fa11e 578 Gene3D G3DSA:1.10.510.10 85 261 3.9E-44 T 14-10-2018 A4R43_39880 5dbfde7e1c5205e6d3c5609d852fa11e 578 Pfam PF00069 Protein kinase domain 7 250 4.3E-41 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_39880 5dbfde7e1c5205e6d3c5609d852fa11e 578 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 122 134 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4R43_39880 5dbfde7e1c5205e6d3c5609d852fa11e 578 Gene3D G3DSA:3.30.200.20 1 84 1.3E-18 T 14-10-2018 A4R43_39880 5dbfde7e1c5205e6d3c5609d852fa11e 578 SUPERFAMILY SSF56112 3 262 3.37E-64 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_39880 5dbfde7e1c5205e6d3c5609d852fa11e 578 SMART SM00220 6 255 2.9E-50 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4R43_09450 b1688565395bd1f3983f4bac91c2711e 410 Gene3D G3DSA:1.20.1250.20 2 410 8.1E-71 T 14-10-2018 A4R43_09450 b1688565395bd1f3983f4bac91c2711e 410 SUPERFAMILY SSF103473 3 407 1.57E-64 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_09450 b1688565395bd1f3983f4bac91c2711e 410 Pfam PF00083 Sugar (and other) transporter 11 409 1.0E-45 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_28635 58704606179c8a498abd80d8f65c7e6e 596 Gene3D G3DSA:1.20.1730.10 279 562 3.3E-17 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_28635 58704606179c8a498abd80d8f65c7e6e 596 Gene3D G3DSA:1.20.1730.10 24 246 2.7E-28 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_28635 58704606179c8a498abd80d8f65c7e6e 596 Pfam PF00474 Sodium:solute symporter family 299 500 6.7E-17 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_28635 58704606179c8a498abd80d8f65c7e6e 596 Pfam PF00474 Sodium:solute symporter family 35 193 2.5E-24 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_32685 5d91172d31ac61688d0b94cfd49b2ae7 235 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 51 168 7.0E-5 T 14-10-2018 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 A4R43_32685 5d91172d31ac61688d0b94cfd49b2ae7 235 Gene3D G3DSA:1.20.5.1230 3 202 1.4E-5 T 14-10-2018 A4R43_23790 e3c26397c358a1780a245cb938eb2394 470 Gene3D G3DSA:1.10.4160.10 8 469 9.4E-115 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily A4R43_23790 e3c26397c358a1780a245cb938eb2394 470 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 24 458 4.7E-98 T 14-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 A4R43_12080 80fbe85b0b93decc28422ded1da4a078 470 Pfam PF13768 von Willebrand factor type A domain 55 210 1.4E-11 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_12080 80fbe85b0b93decc28422ded1da4a078 470 Gene3D G3DSA:3.40.50.410 50 232 3.4E-102 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_12080 80fbe85b0b93decc28422ded1da4a078 470 SMART SM00327 51 227 7.9E-7 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_12080 80fbe85b0b93decc28422ded1da4a078 470 Gene3D G3DSA:2.60.40.3670 17 314 3.4E-102 T 14-10-2018 A4R43_12080 80fbe85b0b93decc28422ded1da4a078 470 SUPERFAMILY SSF53300 55 214 1.93E-20 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_12080 80fbe85b0b93decc28422ded1da4a078 470 Gene3D G3DSA:1.20.120.1690 329 428 7.1E-19 T 14-10-2018 A4R43_02800 b9caf22c3e4db31cdaf6e0fb99b42504 356 Gene3D G3DSA:3.40.50.720 147 325 1.4E-96 T 14-10-2018 A4R43_02800 b9caf22c3e4db31cdaf6e0fb99b42504 356 SUPERFAMILY SSF50129 11 191 1.32E-33 T 14-10-2018 IPR011032 GroES-like superfamily A4R43_02800 b9caf22c3e4db31cdaf6e0fb99b42504 356 Gene3D G3DSA:3.90.180.10 15 349 1.4E-96 T 14-10-2018 A4R43_02800 b9caf22c3e4db31cdaf6e0fb99b42504 356 SUPERFAMILY SSF51735 174 313 1.54E-10 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_02800 b9caf22c3e4db31cdaf6e0fb99b42504 356 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 138 8.7E-13 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4R43_02800 b9caf22c3e4db31cdaf6e0fb99b42504 356 Pfam PF16912 Glucose dehydrogenase C-terminus 145 350 5.3E-63 T 14-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 A4R43_16410 908a448613653af37f28929619c0b655 550 Pfam PF05960 Bacterial protein of unknown function (DUF885) 28 542 3.5E-150 T 14-10-2018 IPR010281 Protein of unknown function DUF885 A4R43_35815 f10aee2c0a4c5ad0bc68ad65f79888dd 299 Gene3D G3DSA:3.40.50.1820 34 297 5.0E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35815 f10aee2c0a4c5ad0bc68ad65f79888dd 299 SUPERFAMILY SSF53474 28 296 3.16E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35815 f10aee2c0a4c5ad0bc68ad65f79888dd 299 PRINTS PR00412 Epoxide hydrolase signature 72 87 3.0E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_35815 f10aee2c0a4c5ad0bc68ad65f79888dd 299 PRINTS PR00412 Epoxide hydrolase signature 238 254 3.0E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_35815 f10aee2c0a4c5ad0bc68ad65f79888dd 299 PRINTS PR00412 Epoxide hydrolase signature 270 292 3.0E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_35815 f10aee2c0a4c5ad0bc68ad65f79888dd 299 PRINTS PR00412 Epoxide hydrolase signature 118 131 3.0E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_35815 f10aee2c0a4c5ad0bc68ad65f79888dd 299 Pfam PF12697 Alpha/beta hydrolase family 48 285 6.8E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_29130 b89ff675f317847fe57c5425114bb203 438 SUPERFAMILY SSF51971 1 307 1.53E-53 T 14-10-2018 A4R43_29130 b89ff675f317847fe57c5425114bb203 438 Gene3D G3DSA:3.50.50.60 39 312 1.2E-143 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_29130 b89ff675f317847fe57c5425114bb203 438 PRINTS PR00419 Adrenodoxin reductase family signature 22 35 4.9E-8 T 14-10-2018 A4R43_29130 b89ff675f317847fe57c5425114bb203 438 PRINTS PR00419 Adrenodoxin reductase family signature 136 150 4.9E-8 T 14-10-2018 A4R43_29130 b89ff675f317847fe57c5425114bb203 438 PRINTS PR00419 Adrenodoxin reductase family signature 65 75 4.9E-8 T 14-10-2018 A4R43_29130 b89ff675f317847fe57c5425114bb203 438 SUPERFAMILY SSF51971 297 433 3.83E-8 T 14-10-2018 A4R43_29130 b89ff675f317847fe57c5425114bb203 438 PIRSF PIRSF000362 1 438 5.4E-161 T 14-10-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4R43_29130 b89ff675f317847fe57c5425114bb203 438 Gene3D G3DSA:3.40.50.720 1 433 1.2E-143 T 14-10-2018 A4R43_29130 b89ff675f317847fe57c5425114bb203 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 163 5.6E-7 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_23955 581d9fea1b7ca5d6b8af9ddfca6c77d1 245 Gene3D G3DSA:1.10.530.10 84 243 3.4E-8 T 14-10-2018 A4R43_23955 581d9fea1b7ca5d6b8af9ddfca6c77d1 245 SUPERFAMILY SSF53955 60 240 8.86E-32 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_09710 54ef8ae8fb2d19bbb57cfcec13cb424e 288 Gene3D G3DSA:3.20.20.30 5 284 5.1E-52 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_09710 54ef8ae8fb2d19bbb57cfcec13cb424e 288 SUPERFAMILY SSF51679 8 260 6.28E-46 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_09710 54ef8ae8fb2d19bbb57cfcec13cb424e 288 Pfam PF00296 Luciferase-like monooxygenase 14 252 4.8E-39 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_22885 2f09580324b36816f388fd70d5ce860e 96 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 84 2.0E-10 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4R43_22885 2f09580324b36816f388fd70d5ce860e 96 SUPERFAMILY SSF143011 2 86 4.32E-19 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A4R43_22885 2f09580324b36816f388fd70d5ce860e 96 Gene3D G3DSA:3.30.2310.20 1 94 4.2E-20 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A4R43_07115 693680f3e6dcde1533b54ee219ce10b7 190 SUPERFAMILY SSF46689 9 89 1.45E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_07115 693680f3e6dcde1533b54ee219ce10b7 190 Gene3D G3DSA:1.10.357.10 4 190 7.3E-47 T 14-10-2018 A4R43_07115 693680f3e6dcde1533b54ee219ce10b7 190 SUPERFAMILY SSF48498 87 189 3.89E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_07115 693680f3e6dcde1533b54ee219ce10b7 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 4.9E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07115 693680f3e6dcde1533b54ee219ce10b7 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07115 693680f3e6dcde1533b54ee219ce10b7 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40770 192fbd219728fb5d2ad678121b4891eb 519 Pfam PF00501 AMP-binding enzyme 30 418 2.1E-53 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_40770 192fbd219728fb5d2ad678121b4891eb 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_40770 192fbd219728fb5d2ad678121b4891eb 519 SUPERFAMILY SSF56801 29 506 1.44E-71 T 14-10-2018 A4R43_40770 192fbd219728fb5d2ad678121b4891eb 519 Gene3D G3DSA:3.40.50.12780 15 415 7.7E-60 T 14-10-2018 A4R43_40770 192fbd219728fb5d2ad678121b4891eb 519 Gene3D G3DSA:3.30.300.30 422 510 3.1E-6 T 14-10-2018 A4R43_21805 e0484d21ab28b7655a67c494b0ed648c 303 Gene3D G3DSA:3.40.50.300 1 227 9.6E-54 T 14-10-2018 A4R43_21805 e0484d21ab28b7655a67c494b0ed648c 303 SUPERFAMILY SSF52540 2 220 1.3E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21805 e0484d21ab28b7655a67c494b0ed648c 303 SMART SM00382 26 204 1.3E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_21805 e0484d21ab28b7655a67c494b0ed648c 303 Pfam PF00005 ABC transporter 17 156 7.1E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_04990 e07e9db9e7fff729c35b2fc5b0647202 738 Pfam PF13538 UvrD-like helicase C-terminal domain 680 726 5.7E-9 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain A4R43_04990 e07e9db9e7fff729c35b2fc5b0647202 738 Gene3D G3DSA:3.40.50.300 415 580 5.6E-8 T 14-10-2018 A4R43_04990 e07e9db9e7fff729c35b2fc5b0647202 738 SUPERFAMILY SSF52540 179 732 5.21E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04990 e07e9db9e7fff729c35b2fc5b0647202 738 Pfam PF02562 PhoH-like protein 493 568 1.6E-4 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 A4R43_04990 e07e9db9e7fff729c35b2fc5b0647202 738 Gene3D G3DSA:3.40.50.300 593 734 3.9E-11 T 14-10-2018 A4R43_04990 e07e9db9e7fff729c35b2fc5b0647202 738 Gene3D G3DSA:3.40.50.300 178 405 5.4E-10 T 14-10-2018 A4R43_00705 023894e40483e2be693c6b1a8e8f2754 179 Gene3D G3DSA:1.10.150.20 125 179 2.9E-8 T 14-10-2018 A4R43_00705 023894e40483e2be693c6b1a8e8f2754 179 SUPERFAMILY SSF47789 127 177 8.24E-6 T 14-10-2018 A4R43_03160 5a06c489d2ddbf76c898a470fb337fd6 218 Gene3D G3DSA:2.70.50.50 36 217 6.5E-56 T 14-10-2018 A4R43_03160 5a06c489d2ddbf76c898a470fb337fd6 218 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 36 215 8.2E-29 T 14-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal A4R43_03160 5a06c489d2ddbf76c898a470fb337fd6 218 SUPERFAMILY SSF81296 36 218 3.5E-27 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_07205 c58d7fa18b0164ac56b09a7d0bba153e 117 Pfam PF07883 Cupin domain 32 99 1.4E-18 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_07205 c58d7fa18b0164ac56b09a7d0bba153e 117 SUPERFAMILY SSF51182 7 103 7.76E-25 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_07205 c58d7fa18b0164ac56b09a7d0bba153e 117 Gene3D G3DSA:2.60.120.10 7 114 7.9E-23 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_34215 970b8b0ac542f5b66d1bf722f1d59de0 150 Gene3D G3DSA:3.40.50.300 1 144 4.8E-32 T 14-10-2018 A4R43_34215 970b8b0ac542f5b66d1bf722f1d59de0 150 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 127 7.1E-30 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A4R43_34215 970b8b0ac542f5b66d1bf722f1d59de0 150 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 134 1.3E-21 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A4R43_34215 970b8b0ac542f5b66d1bf722f1d59de0 150 SUPERFAMILY SSF52540 18 126 1.4E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 SUPERFAMILY SSF52096 17 191 4.8E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 190 38.156 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 PRINTS PR00127 Clp protease catalytic subunit P signature 87 104 1.2E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 PRINTS PR00127 Clp protease catalytic subunit P signature 16 31 1.2E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 PRINTS PR00127 Clp protease catalytic subunit P signature 165 184 1.2E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 PRINTS PR00127 Clp protease catalytic subunit P signature 108 127 1.2E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 PRINTS PR00127 Clp protease catalytic subunit P signature 56 76 1.2E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 Pfam PF00574 Clp protease 15 189 7.0E-75 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4R43_39045 6c0fef23b593f590648ef59ce93a193f 198 Gene3D G3DSA:3.90.226.10 2 191 5.9E-71 T 14-10-2018 A4R43_30895 5f61614d8628085ac32e143e5ced3dd6 359 SUPERFAMILY SSF55874 257 357 1.36E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_30895 5f61614d8628085ac32e143e5ced3dd6 359 Pfam PF07730 Histidine kinase 166 230 1.6E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_30895 5f61614d8628085ac32e143e5ced3dd6 359 Gene3D G3DSA:3.30.565.10 239 357 2.2E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_25705 09f27420af7191336403763902a54ac0 230 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_25705 09f27420af7191336403763902a54ac0 230 Gene3D G3DSA:3.40.50.300 4 229 5.3E-64 T 14-10-2018 A4R43_25705 09f27420af7191336403763902a54ac0 230 SUPERFAMILY SSF52540 5 219 8.82E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25705 09f27420af7191336403763902a54ac0 230 PRINTS PR00364 Disease resistance protein signature 33 48 4.7E-5 T 14-10-2018 A4R43_25705 09f27420af7191336403763902a54ac0 230 PRINTS PR00364 Disease resistance protein signature 116 130 4.7E-5 T 14-10-2018 A4R43_25705 09f27420af7191336403763902a54ac0 230 PRINTS PR00364 Disease resistance protein signature 204 218 4.7E-5 T 14-10-2018 A4R43_25705 09f27420af7191336403763902a54ac0 230 Pfam PF00005 ABC transporter 21 169 2.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_25705 09f27420af7191336403763902a54ac0 230 SMART SM00382 30 217 4.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_33835 dc57976063a8487d190660090454db65 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.4E-46 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33835 dc57976063a8487d190660090454db65 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33835 dc57976063a8487d190660090454db65 101 SUPERFAMILY SSF54999 5 100 1.07E-36 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A4R43_33835 dc57976063a8487d190660090454db65 101 SMART SM01403 7 101 3.0E-55 T 14-10-2018 IPR027486 Ribosomal protein S10 domain A4R43_33835 dc57976063a8487d190660090454db65 101 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.7E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33835 dc57976063a8487d190660090454db65 101 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.7E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33835 dc57976063a8487d190660090454db65 101 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.7E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33835 dc57976063a8487d190660090454db65 101 Gene3D G3DSA:3.30.70.600 1 101 4.5E-36 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A4R43_33835 dc57976063a8487d190660090454db65 101 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 1.1E-34 T 14-10-2018 IPR027486 Ribosomal protein S10 domain A4R43_33835 dc57976063a8487d190660090454db65 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 101 24.494 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_24340 5608922fb8db1ff4bcaca271743b9ccd 304 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 22 271 2.0E-47 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region A4R43_24340 5608922fb8db1ff4bcaca271743b9ccd 304 Gene3D G3DSA:2.120.10.30 12 302 1.3E-42 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_24340 5608922fb8db1ff4bcaca271743b9ccd 304 SUPERFAMILY SSF63829 12 291 1.34E-47 T 14-10-2018 A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 Gene3D G3DSA:3.20.20.100 12 279 1.0E-78 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 PRINTS PR00069 Aldo-keto reductase signature 109 127 1.1E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 PRINTS PR00069 Aldo-keto reductase signature 45 69 1.1E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 PRINTS PR00069 Aldo-keto reductase signature 173 202 1.1E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 PRINTS PR00069 Aldo-keto reductase signature 140 157 1.1E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 PRINTS PR00069 Aldo-keto reductase signature 209 233 1.1E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 Pfam PF00248 Aldo/keto reductase family 211 274 9.7E-14 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 Pfam PF00248 Aldo/keto reductase family 19 205 1.4E-43 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_38345 6996e8dad5c0a3971176729176755aa1 280 SUPERFAMILY SSF51430 13 274 7.07E-73 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_17345 1f1ed328ef2a70e3e7e37ef16eb34df9 194 SUPERFAMILY SSF52540 14 186 9.81E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17345 1f1ed328ef2a70e3e7e37ef16eb34df9 194 Pfam PF03029 Conserved hypothetical ATP binding protein 18 186 3.9E-26 T 14-10-2018 IPR004130 GPN-loop GTPase A4R43_17345 1f1ed328ef2a70e3e7e37ef16eb34df9 194 Gene3D G3DSA:3.40.50.300 10 190 3.6E-16 T 14-10-2018 A4R43_21790 c303372b0677ee443c084787bb8691ff 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 259 6.3E-50 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_21790 c303372b0677ee443c084787bb8691ff 278 SUPERFAMILY SSF53850 10 263 5.66E-52 T 14-10-2018 A4R43_21790 c303372b0677ee443c084787bb8691ff 278 Gene3D G3DSA:3.40.190.10 39 256 7.2E-64 T 14-10-2018 A4R43_21790 c303372b0677ee443c084787bb8691ff 278 Gene3D G3DSA:3.40.190.10 131 223 7.2E-64 T 14-10-2018 A4R43_21790 c303372b0677ee443c084787bb8691ff 278 SMART SM00062 41 265 6.1E-59 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4R43_39180 f360489575b5bf3b4a04cbbfb4209e87 200 Pfam PF13649 Methyltransferase domain 25 111 1.4E-16 T 14-10-2018 A4R43_39180 f360489575b5bf3b4a04cbbfb4209e87 200 SUPERFAMILY SSF53335 6 150 1.47E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_39180 f360489575b5bf3b4a04cbbfb4209e87 200 Gene3D G3DSA:3.40.50.150 2 136 7.2E-30 T 14-10-2018 A4R43_28350 d134f0679152f8f6a160281ba726fc9c 320 Pfam PF12079 Protein of unknown function (DUF3558) 12 160 5.1E-9 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_28350 d134f0679152f8f6a160281ba726fc9c 320 Pfam PF12079 Protein of unknown function (DUF3558) 172 315 1.3E-13 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_01990 26061d11c55a13c423551c487d4608a8 224 SUPERFAMILY SSF46785 6 106 1.39E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_01990 26061d11c55a13c423551c487d4608a8 224 Pfam PF01638 HxlR-like helix-turn-helix 17 103 1.2E-18 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_01990 26061d11c55a13c423551c487d4608a8 224 Gene3D G3DSA:1.10.10.10 3 140 5.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13210 d7af4c20ce932786ea7991ef947d202e 123 Pfam PF05331 Protein of unknown function (DUF742) 12 120 1.5E-32 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_36830 18a88939b61a7fa53d3fd768c19cd418 336 Pfam PF03631 Virulence factor BrkB 32 281 1.3E-40 T 14-10-2018 IPR017039 Virulence factor BrkB A4R43_01210 5ff38250280b029d9c4e94baf95ce24f 301 Pfam PF05709 Phage tail protein 32 244 1.3E-9 T 14-10-2018 IPR008841 Siphovirus-type tail component A4R43_09120 b61cbba6f87c7e5cc071bd60099c30ab 467 SUPERFAMILY SSF53850 19 457 8.03E-38 T 14-10-2018 A4R43_09120 b61cbba6f87c7e5cc071bd60099c30ab 467 Pfam PF01547 Bacterial extracellular solute-binding protein 74 373 6.8E-18 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_09120 b61cbba6f87c7e5cc071bd60099c30ab 467 Gene3D G3DSA:3.40.190.10 89 415 1.9E-38 T 14-10-2018 A4R43_09120 b61cbba6f87c7e5cc071bd60099c30ab 467 Gene3D G3DSA:3.40.190.10 184 449 1.9E-38 T 14-10-2018 A4R43_03805 533feb17ee30612184da0d33376348c4 359 Gene3D G3DSA:1.10.10.2120 25 97 6.5E-61 T 14-10-2018 A4R43_03805 533feb17ee30612184da0d33376348c4 359 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 120 282 4.2E-15 T 14-10-2018 IPR005079 Peptidase C45 A4R43_03805 533feb17ee30612184da0d33376348c4 359 Gene3D G3DSA:3.60.60.10 13 342 6.5E-61 T 14-10-2018 A4R43_30930 7ff4978d8c4dbda1434a003d89630c41 220 SUPERFAMILY SSF53335 2 219 5.63E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_30930 7ff4978d8c4dbda1434a003d89630c41 220 Pfam PF02390 Putative methyltransferase 48 210 8.2E-55 T 14-10-2018 A4R43_30930 7ff4978d8c4dbda1434a003d89630c41 220 Gene3D G3DSA:3.40.50.150 11 220 6.4E-69 T 14-10-2018 A4R43_30930 7ff4978d8c4dbda1434a003d89630c41 220 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 39 219 1.2E-48 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4R43_30930 7ff4978d8c4dbda1434a003d89630c41 220 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 5 220 30.136 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4R43_30170 a6efbeee3a5af8f34d349125c19fbd27 596 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 570 2.6E-256 T 14-10-2018 IPR021941 Protein of unknown function DUF3556, transmembrane A4R43_04240 5463260ed52d1c75c81a434fc271e241 275 Pfam PF02517 CAAX protease self-immunity 127 212 2.6E-16 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A4R43_19745 5f7e9dc558c72dca307e9bca6fbc61af 109 Gene3D G3DSA:1.10.10.10 6 109 2.5E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19745 5f7e9dc558c72dca307e9bca6fbc61af 109 Pfam PF01638 HxlR-like helix-turn-helix 20 107 1.6E-29 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_19745 5f7e9dc558c72dca307e9bca6fbc61af 109 SUPERFAMILY SSF46785 10 107 1.47E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15770 05687c22266e9982357893e87564dd97 378 Gene3D G3DSA:3.40.50.2300 51 339 9.7E-94 T 14-10-2018 A4R43_15770 05687c22266e9982357893e87564dd97 378 Pfam PF13407 Periplasmic binding protein domain 54 314 1.2E-55 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_15770 05687c22266e9982357893e87564dd97 378 SUPERFAMILY SSF53822 50 351 5.01E-57 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_15770 05687c22266e9982357893e87564dd97 378 Gene3D G3DSA:3.40.50.2300 154 357 9.7E-94 T 14-10-2018 A4R43_34605 946e90284e7563bee5bba19dbb9cac57 243 Gene3D G3DSA:3.60.15.10 1 243 4.9E-60 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_34605 946e90284e7563bee5bba19dbb9cac57 243 SMART SM00849 19 210 3.5E-4 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_34605 946e90284e7563bee5bba19dbb9cac57 243 SUPERFAMILY SSF56281 3 243 9.3E-47 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_34605 946e90284e7563bee5bba19dbb9cac57 243 Pfam PF12706 Beta-lactamase superfamily domain 52 211 2.5E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_16085 7dbde9f4fe86df3a9a08ca207854d99b 132 Gene3D G3DSA:3.10.129.10 3 127 2.6E-27 T 14-10-2018 A4R43_16085 7dbde9f4fe86df3a9a08ca207854d99b 132 SUPERFAMILY SSF54637 4 129 6.34E-13 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_40005 58eeb12da14ef22051847e74ff9e6a60 201 SUPERFAMILY SSF51569 3 194 1.15E-47 T 14-10-2018 A4R43_40005 58eeb12da14ef22051847e74ff9e6a60 201 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 116 129 - T 14-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4R43_40005 58eeb12da14ef22051847e74ff9e6a60 201 Pfam PF01081 KDPG and KHG aldolase 5 174 1.9E-26 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4R43_40005 58eeb12da14ef22051847e74ff9e6a60 201 Gene3D G3DSA:3.20.20.70 1 197 4.0E-51 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_16955 78fab0af6d5fe39769146ae2d7975962 253 SUPERFAMILY SSF54593 13 181 5.5E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16955 78fab0af6d5fe39769146ae2d7975962 253 Gene3D G3DSA:3.10.180.10 7 130 6.4E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16955 78fab0af6d5fe39769146ae2d7975962 253 Gene3D G3DSA:3.10.180.10 136 253 1.3E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16955 78fab0af6d5fe39769146ae2d7975962 253 SUPERFAMILY SSF54593 142 253 1.19E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_16955 78fab0af6d5fe39769146ae2d7975962 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 123 1.4E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_16955 78fab0af6d5fe39769146ae2d7975962 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 147 248 1.1E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_22655 685327fbbcc34451953a0689db1d1805 799 SUPERFAMILY SSF48452 247 328 3.54E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_22655 685327fbbcc34451953a0689db1d1805 799 Gene3D G3DSA:1.25.40.10 242 311 7.7E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_22655 685327fbbcc34451953a0689db1d1805 799 Pfam PF13414 TPR repeat 251 290 1.1E-6 T 14-10-2018 A4R43_24200 ec923827f589b4d2ff286eb015edd66a 270 SUPERFAMILY SSF52266 5 190 1.45E-34 T 14-10-2018 A4R43_24200 ec923827f589b4d2ff286eb015edd66a 270 Gene3D G3DSA:3.40.50.1110 4 192 6.4E-31 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_24200 ec923827f589b4d2ff286eb015edd66a 270 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 8 181 5.1E-29 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_12950 c5fe28d7c5a152db642be0834c78e403 654 SUPERFAMILY SSF48452 447 586 3.8E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12950 c5fe28d7c5a152db642be0834c78e403 654 Pfam PF00931 NB-ARC domain 37 275 2.9E-9 T 14-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A4R43_12950 c5fe28d7c5a152db642be0834c78e403 654 Gene3D G3DSA:1.25.40.10 417 653 3.1E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12950 c5fe28d7c5a152db642be0834c78e403 654 Gene3D G3DSA:3.40.50.300 1 164 5.8E-11 T 14-10-2018 A4R43_12950 c5fe28d7c5a152db642be0834c78e403 654 SUPERFAMILY SSF52540 11 268 9.11E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21555 09c3476385d39e51f1d04c220d5a978d 378 SUPERFAMILY SSF51679 1 367 1.57E-54 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_21555 09c3476385d39e51f1d04c220d5a978d 378 Gene3D G3DSA:3.20.20.30 5 364 2.1E-66 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_21555 09c3476385d39e51f1d04c220d5a978d 378 Pfam PF00296 Luciferase-like monooxygenase 19 336 3.7E-47 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_04000 51528fd0271a8a0bc349e500029f86a4 129 SUPERFAMILY SSF55298 4 129 5.18E-28 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_04000 51528fd0271a8a0bc349e500029f86a4 129 Gene3D G3DSA:3.30.1330.40 3 129 1.4E-29 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_04000 51528fd0271a8a0bc349e500029f86a4 129 Pfam PF01042 Endoribonuclease L-PSP 18 129 4.0E-22 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4R43_07035 f671e69e9fad583de24bacdabf4f74f5 422 Pfam PF01547 Bacterial extracellular solute-binding protein 50 332 2.8E-39 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_07035 f671e69e9fad583de24bacdabf4f74f5 422 Gene3D G3DSA:3.40.190.10 18 420 8.1E-73 T 14-10-2018 A4R43_07035 f671e69e9fad583de24bacdabf4f74f5 422 SUPERFAMILY SSF53850 19 420 4.35E-69 T 14-10-2018 A4R43_37830 00c702a0254248fa14ba8551d350b803 449 Gene3D G3DSA:3.50.50.60 5 441 3.3E-139 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37830 00c702a0254248fa14ba8551d350b803 449 SUPERFAMILY SSF51905 15 240 1.1E-17 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37830 00c702a0254248fa14ba8551d350b803 449 SUPERFAMILY SSF51905 210 436 9.47E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37830 00c702a0254248fa14ba8551d350b803 449 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 15 357 8.0E-111 T 14-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A4R43_06330 6d67fddcc99e259a8d786786ed46e0a9 194 Pfam PF05331 Protein of unknown function (DUF742) 85 193 1.2E-26 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_05025 e2a1d58bf93fc71beb9d377aab86cdc3 273 PIRSF PIRSF006648 21 272 3.7E-21 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_05025 e2a1d58bf93fc71beb9d377aab86cdc3 273 Pfam PF01061 ABC-2 type transporter 61 242 5.4E-14 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_27190 6c0c1c5202d6f26accba7319a3020326 90 SUPERFAMILY SSF143120 5 44 2.22E-6 T 14-10-2018 IPR036165 YefM-like superfamily A4R43_27190 6c0c1c5202d6f26accba7319a3020326 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 42 4.2E-5 T 14-10-2018 A4R43_27190 6c0c1c5202d6f26accba7319a3020326 90 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 41 6.7E-6 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4R43_13390 bb9d7aa40e6edcf8eb2b3e41bf719742 255 Pfam PF17409 MoaF C-terminal domain 137 245 1.2E-35 T 14-10-2018 IPR035348 MoaF, C-terminal domain A4R43_13390 bb9d7aa40e6edcf8eb2b3e41bf719742 255 Pfam PF10703 MoaF N-terminal domain 7 106 5.2E-16 T 14-10-2018 IPR024724 Molybdenum cofactor biosynthesis protein F, N-terminal A4R43_32020 94d63b76b013197a0e907c3e2864da82 318 Pfam PF06089 L-asparaginase II 6 315 4.1E-109 T 14-10-2018 IPR010349 L-asparaginase II A4R43_36390 cc0a925ae04b78ed4c06c6ce55e9291a 157 PIRSF PIRSF000239 2 154 2.1E-21 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_36390 cc0a925ae04b78ed4c06c6ce55e9291a 157 SUPERFAMILY SSF52833 4 153 2.78E-48 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_36390 cc0a925ae04b78ed4c06c6ce55e9291a 157 Pfam PF00578 AhpC/TSA family 8 134 1.6E-40 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_36390 cc0a925ae04b78ed4c06c6ce55e9291a 157 Gene3D G3DSA:3.40.30.10 5 154 6.1E-50 T 14-10-2018 A4R43_03450 7d289dc99ab0dd7f784d037d086b301c 438 Pfam PF03600 Citrate transporter 264 415 4.3E-8 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A4R43_03450 7d289dc99ab0dd7f784d037d086b301c 438 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 149 2.1E-57 T 14-10-2018 IPR009827 Dicarboxylate carrier MatC N-terminal A4R43_30520 201616623b4eebd90bf35f0925884488 214 SUPERFAMILY SSF161098 10 196 1.09E-33 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_30520 201616623b4eebd90bf35f0925884488 214 Gene3D G3DSA:1.10.3720.10 2 211 9.3E-41 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_30520 201616623b4eebd90bf35f0925884488 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 210 1.8E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_30520 201616623b4eebd90bf35f0925884488 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 104 2.1E-23 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_09590 e94202919baa984ba05bf2f87d0b65df 282 Pfam PF00561 alpha/beta hydrolase fold 52 151 6.1E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09590 e94202919baa984ba05bf2f87d0b65df 282 Gene3D G3DSA:3.40.50.1820 2 278 1.6E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_09590 e94202919baa984ba05bf2f87d0b65df 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 227 241 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09590 e94202919baa984ba05bf2f87d0b65df 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09590 e94202919baa984ba05bf2f87d0b65df 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09590 e94202919baa984ba05bf2f87d0b65df 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 77 92 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_09590 e94202919baa984ba05bf2f87d0b65df 282 SUPERFAMILY SSF53474 22 266 2.57E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38275 de77ddba712cb01285f01a79ac5ae2e7 236 Pfam PF00881 Nitroreductase family 51 233 6.4E-25 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4R43_38275 de77ddba712cb01285f01a79ac5ae2e7 236 Gene3D G3DSA:3.40.109.10 6 234 1.1E-53 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_38275 de77ddba712cb01285f01a79ac5ae2e7 236 SUPERFAMILY SSF55469 46 233 3.66E-24 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_38275 de77ddba712cb01285f01a79ac5ae2e7 236 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 67 232 3.0E-34 T 14-10-2018 IPR020051 SagB-type dehydrogenase domain A4R43_06975 a1442421aa9e37d0f400d920fe24aa82 145 SUPERFAMILY SSF46955 14 130 3.59E-29 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily A4R43_06975 a1442421aa9e37d0f400d920fe24aa82 145 Pfam PF13411 MerR HTH family regulatory protein 15 80 7.2E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_06975 a1442421aa9e37d0f400d920fe24aa82 145 SMART SM00422 14 84 5.7E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_06975 a1442421aa9e37d0f400d920fe24aa82 145 ProSitePatterns PS00552 MerR-type HTH domain signature. 17 39 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4R43_06975 a1442421aa9e37d0f400d920fe24aa82 145 Gene3D G3DSA:1.10.1660.10 13 137 1.8E-31 T 14-10-2018 A4R43_32570 793b84fc91e69cfe29d0a21e41a06dd2 282 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 18 252 1.7E-47 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 A4R43_14725 0c51e89bf5d08be6dc5bf3dacbc9c247 502 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 61 221 2.3E-17 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4R43_06140 13e04daf09328d64429a954c0c6ad58c 207 SUPERFAMILY SSF46689 7 89 4.39E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_06140 13e04daf09328d64429a954c0c6ad58c 207 Gene3D G3DSA:1.10.357.10 8 201 5.7E-40 T 14-10-2018 A4R43_06140 13e04daf09328d64429a954c0c6ad58c 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_06140 13e04daf09328d64429a954c0c6ad58c 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.4E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06140 13e04daf09328d64429a954c0c6ad58c 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 6.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_06140 13e04daf09328d64429a954c0c6ad58c 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_16720 28c7447e1dd5294e700906e4fe5de6fe 310 Gene3D G3DSA:3.40.710.10 72 302 2.8E-21 T 14-10-2018 A4R43_16720 28c7447e1dd5294e700906e4fe5de6fe 310 SUPERFAMILY SSF56601 78 292 2.29E-14 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_06065 8d4be7c6033f34408d4520a330ef93af 380 Gene3D G3DSA:3.40.50.1820 1 284 4.5E-76 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06065 8d4be7c6033f34408d4520a330ef93af 380 Pfam PF00135 Carboxylesterase family 3 262 1.3E-60 T 14-10-2018 IPR002018 Carboxylesterase, type B A4R43_06065 8d4be7c6033f34408d4520a330ef93af 380 Gene3D G3DSA:3.40.50.1820 285 376 5.1E-9 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06065 8d4be7c6033f34408d4520a330ef93af 380 SUPERFAMILY SSF53474 3 366 1.95E-77 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22755 6cb5bee27858a6816406cbda3c22a113 324 Pfam PF00248 Aldo/keto reductase family 15 308 1.3E-78 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_22755 6cb5bee27858a6816406cbda3c22a113 324 Gene3D G3DSA:3.20.20.100 3 320 1.5E-115 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_22755 6cb5bee27858a6816406cbda3c22a113 324 SUPERFAMILY SSF51430 1 311 9.43E-102 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_35610 fba3fb092d056e7e0e4247f51064f0c4 150 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 141 1.8E-9 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_35610 fba3fb092d056e7e0e4247f51064f0c4 150 Gene3D G3DSA:3.30.530.20 5 147 1.2E-14 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_35610 fba3fb092d056e7e0e4247f51064f0c4 150 SUPERFAMILY SSF55961 1 144 6.11E-21 T 14-10-2018 A4R43_30745 7dbec0da59c4fe7f4a0ed1917cabfbf2 215 Pfam PF12079 Protein of unknown function (DUF3558) 18 210 1.9E-25 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_14245 adca3b1c170951ed19bd96a4290264d7 328 PIRSF PIRSF000915 2 248 3.6E-61 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4R43_14245 adca3b1c170951ed19bd96a4290264d7 328 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 13 231 6.3E-34 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4R43_14245 adca3b1c170951ed19bd96a4290264d7 328 Gene3D G3DSA:3.40.50.1000 10 234 1.1E-75 T 14-10-2018 IPR023214 HAD superfamily A4R43_14245 adca3b1c170951ed19bd96a4290264d7 328 Pfam PF13344 Haloacid dehalogenase-like hydrolase 12 112 6.3E-25 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4R43_14245 adca3b1c170951ed19bd96a4290264d7 328 Pfam PF13242 HAD-hyrolase-like 188 254 5.5E-12 T 14-10-2018 A4R43_14245 adca3b1c170951ed19bd96a4290264d7 328 Gene3D G3DSA:3.40.50.1000 77 188 1.1E-75 T 14-10-2018 IPR023214 HAD superfamily A4R43_14245 adca3b1c170951ed19bd96a4290264d7 328 SUPERFAMILY SSF56784 9 240 1.1E-53 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_13515 f99eb980ed5fab85359f16ee08bd61bb 307 SUPERFAMILY SSF53474 54 303 4.99E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13515 f99eb980ed5fab85359f16ee08bd61bb 307 Gene3D G3DSA:3.40.50.1820 1 305 5.8E-79 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13515 f99eb980ed5fab85359f16ee08bd61bb 307 Pfam PF07859 alpha/beta hydrolase fold 80 279 5.7E-52 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4R43_27665 1520d2bb80254802423cbb1922b2ecc7 78 Pfam PF14013 MT0933-like antitoxin protein 10 55 2.8E-14 T 14-10-2018 IPR028037 Antitoxin Rv0909/MT0933 A4R43_32635 c0102208c15e21302807296d22842c33 428 Pfam PF04286 Protein of unknown function (DUF445) 64 426 4.6E-108 T 14-10-2018 IPR007383 Protein of unknown function DUF445 A4R43_09915 7890b14666b186c5c4f448cce5e1c7b1 80 SUPERFAMILY SSF47336 5 77 1.1E-11 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_09915 7890b14666b186c5c4f448cce5e1c7b1 80 Pfam PF00550 Phosphopantetheine attachment site 9 72 8.4E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_09915 7890b14666b186c5c4f448cce5e1c7b1 80 Gene3D G3DSA:1.10.1200.10 4 78 6.6E-24 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_38315 09256fd465f8026178f8a4974fd420f7 235 Gene3D G3DSA:3.30.530.20 2 154 1.2E-16 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_38315 09256fd465f8026178f8a4974fd420f7 235 SUPERFAMILY SSF55961 5 127 1.1E-17 T 14-10-2018 A4R43_08370 b74f218f8f4e026437019222813de917 257 Pfam PF00535 Glycosyl transferase family 2 16 180 9.8E-31 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_08370 b74f218f8f4e026437019222813de917 257 SUPERFAMILY SSF53448 13 228 2.01E-43 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_08370 b74f218f8f4e026437019222813de917 257 Gene3D G3DSA:3.90.550.10 3 249 2.3E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_27790 aceae7b5f4774cede7e8208cbfa5636f 331 SUPERFAMILY SSF53187 42 278 1.62E-27 T 14-10-2018 A4R43_27790 aceae7b5f4774cede7e8208cbfa5636f 331 Gene3D G3DSA:3.40.630.10 34 303 3.8E-27 T 14-10-2018 A4R43_27790 aceae7b5f4774cede7e8208cbfa5636f 331 Pfam PF00246 Zinc carboxypeptidase 43 162 7.1E-16 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_26930 5f55f3d874154b4ee6abdf5c7a36eca2 495 Pfam PF03235 Protein of unknown function DUF262 28 104 1.4E-14 T 14-10-2018 IPR004919 Domain of unknown function DUF262 A4R43_38815 662e11cdc3232369bfb6978d24eae8af 1645 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 78 1641 0.0 T 14-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 A4R43_38815 662e11cdc3232369bfb6978d24eae8af 1645 SUPERFAMILY SSF51735 975 1247 5.58E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38815 662e11cdc3232369bfb6978d24eae8af 1645 PIRSF PIRSF036761 3 1645 0.0 T 14-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 A4R43_38815 662e11cdc3232369bfb6978d24eae8af 1645 SUPERFAMILY SSF53223 789 986 1.21E-22 T 14-10-2018 A4R43_07360 888ce0b7fd29192a87a0781ba960262d 133 SUPERFAMILY SSF54427 8 132 7.83E-25 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_07360 888ce0b7fd29192a87a0781ba960262d 133 Gene3D G3DSA:3.10.450.50 5 132 8.8E-21 T 14-10-2018 A4R43_07360 888ce0b7fd29192a87a0781ba960262d 133 Pfam PF13577 SnoaL-like domain 8 127 1.2E-14 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_36560 b81c36369738e0039edbe64629f212e5 249 Gene3D G3DSA:3.40.50.150 2 249 1.2E-93 T 14-10-2018 A4R43_36560 b81c36369738e0039edbe64629f212e5 249 Pfam PF13649 Methyltransferase domain 42 135 4.3E-11 T 14-10-2018 A4R43_36560 b81c36369738e0039edbe64629f212e5 249 SUPERFAMILY SSF53335 11 245 3.47E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_36560 b81c36369738e0039edbe64629f212e5 249 PIRSF PIRSF034653 2 249 5.5E-107 T 14-10-2018 IPR017031 Predicted S-adenosyl-L-methionine dependent methyltransferase, YjhP-type A4R43_08940 706c4f2849016b90f28830b4f1e65e23 191 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 180 6.7E-81 T 14-10-2018 IPR021441 Protein of unknown function DUF3090 A4R43_08940 706c4f2849016b90f28830b4f1e65e23 191 Pfam PF11290 Protein of unknown function (DUF3090) 6 176 4.9E-71 T 14-10-2018 IPR021441 Protein of unknown function DUF3090 A4R43_29030 c464e9389031fa4103fe814bf68a2814 255 SMART SM00382 26 223 1.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_29030 c464e9389031fa4103fe814bf68a2814 255 Gene3D G3DSA:3.40.50.300 1 255 1.9E-80 T 14-10-2018 A4R43_29030 c464e9389031fa4103fe814bf68a2814 255 Pfam PF00005 ABC transporter 18 175 6.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_29030 c464e9389031fa4103fe814bf68a2814 255 SUPERFAMILY SSF52540 2 248 7.55E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_29030 c464e9389031fa4103fe814bf68a2814 255 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_37195 b7134354f823723f6423f432efd25a7d 480 Pfam PF13416 Bacterial extracellular solute-binding protein 28 343 2.0E-29 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_37195 b7134354f823723f6423f432efd25a7d 480 Gene3D G3DSA:3.40.190.10 27 386 6.8E-65 T 14-10-2018 A4R43_37195 b7134354f823723f6423f432efd25a7d 480 SUPERFAMILY SSF53850 6 411 2.05E-43 T 14-10-2018 A4R43_37195 b7134354f823723f6423f432efd25a7d 480 Gene3D G3DSA:3.40.190.10 133 415 6.8E-65 T 14-10-2018 A4R43_26330 817ab264573f3f579db96b976cafd05d 323 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_26330 817ab264573f3f579db96b976cafd05d 323 SUPERFAMILY SSF52540 4 226 1.07E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_26330 817ab264573f3f579db96b976cafd05d 323 Gene3D G3DSA:3.40.50.300 2 235 5.9E-64 T 14-10-2018 A4R43_26330 817ab264573f3f579db96b976cafd05d 323 SMART SM00382 29 212 1.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_26330 817ab264573f3f579db96b976cafd05d 323 Pfam PF00005 ABC transporter 21 163 1.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_26330 817ab264573f3f579db96b976cafd05d 323 Pfam PF13732 Domain of unknown function (DUF4162) 217 306 1.4E-7 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 A4R43_26330 817ab264573f3f579db96b976cafd05d 323 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 308 2.1E-112 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4R43_24240 b33f292286aef4b324e941d95b7facf5 226 Gene3D G3DSA:3.10.180.10 13 104 2.3E-12 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_24240 b33f292286aef4b324e941d95b7facf5 226 Gene3D G3DSA:3.10.180.10 111 226 1.5E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_24240 b33f292286aef4b324e941d95b7facf5 226 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 115 221 4.5E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_24240 b33f292286aef4b324e941d95b7facf5 226 SUPERFAMILY SSF54593 114 222 8.25E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_24240 b33f292286aef4b324e941d95b7facf5 226 SUPERFAMILY SSF54593 23 97 1.51E-7 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_09845 5a2ad447dc865d3c666513bc51e446f5 263 Pfam PF14011 EspG family 17 254 3.1E-30 T 14-10-2018 IPR025734 EspG family A4R43_10720 8e42fe7cca3b3ec7e7b0cb532826be6a 296 SUPERFAMILY SSF111331 5 288 7.85E-69 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A4R43_10720 8e42fe7cca3b3ec7e7b0cb532826be6a 296 Gene3D G3DSA:3.40.50.10330 2 125 7.1E-27 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A4R43_10720 8e42fe7cca3b3ec7e7b0cb532826be6a 296 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 126 1.9E-23 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4R43_10720 8e42fe7cca3b3ec7e7b0cb532826be6a 296 Gene3D G3DSA:2.60.200.40 126 282 9.6E-42 T 14-10-2018 A4R43_10720 8e42fe7cca3b3ec7e7b0cb532826be6a 296 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 287 4.6E-41 T 14-10-2018 IPR005218 Diacylglycerol/lipid kinase A4R43_35850 69ece2629dc206dbefe3fbd14540db1d 255 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 1.9E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35850 69ece2629dc206dbefe3fbd14540db1d 255 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 58 1.9E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_35850 69ece2629dc206dbefe3fbd14540db1d 255 SUPERFAMILY SSF48498 114 224 1.13E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_35850 69ece2629dc206dbefe3fbd14540db1d 255 Gene3D G3DSA:1.10.357.10 29 233 7.7E-38 T 14-10-2018 A4R43_35850 69ece2629dc206dbefe3fbd14540db1d 255 SUPERFAMILY SSF46689 31 112 3.35E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_35850 69ece2629dc206dbefe3fbd14540db1d 255 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 90 5.3E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_12090 e917dd45fc3ce14f58100eee4db5974e 454 Gene3D G3DSA:2.40.10.120 2 177 1.4E-6 T 14-10-2018 A4R43_12090 e917dd45fc3ce14f58100eee4db5974e 454 SUPERFAMILY SSF50494 5 175 1.7E-13 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_12090 e917dd45fc3ce14f58100eee4db5974e 454 Pfam PF13365 Trypsin-like peptidase domain 5 147 1.7E-11 T 14-10-2018 A4R43_09415 b7af4960dd4008a64d802dd63ed710d5 162 Gene3D G3DSA:3.50.30.40 4 162 2.8E-60 T 14-10-2018 A4R43_09415 b7af4960dd4008a64d802dd63ed710d5 162 TIGRFAM TIGR01935 NOT-MenG: RraA family 9 157 4.3E-62 T 14-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 A4R43_09415 b7af4960dd4008a64d802dd63ed710d5 162 SUPERFAMILY SSF89562 9 161 3.66E-47 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily A4R43_09415 b7af4960dd4008a64d802dd63ed710d5 162 Pfam PF03737 Aldolase/RraA 9 157 1.9E-42 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A4R43_20030 8419b604846a20b804f7475119bf7a6b 250 SUPERFAMILY SSF51182 13 144 1.78E-12 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_20030 8419b604846a20b804f7475119bf7a6b 250 Gene3D G3DSA:2.60.120.10 1 109 1.5E-9 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_07820 7e26912a49cd893b71a010ee788f87f7 309 SUPERFAMILY SSF53850 87 301 3.26E-35 T 14-10-2018 A4R43_07820 7e26912a49cd893b71a010ee788f87f7 309 Gene3D G3DSA:3.40.190.10 92 286 2.4E-42 T 14-10-2018 A4R43_07820 7e26912a49cd893b71a010ee788f87f7 309 Gene3D G3DSA:1.10.10.10 3 88 3.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_07820 7e26912a49cd893b71a010ee788f87f7 309 SUPERFAMILY SSF46785 4 112 2.93E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_07820 7e26912a49cd893b71a010ee788f87f7 309 Gene3D G3DSA:3.40.190.10 170 272 2.4E-42 T 14-10-2018 A4R43_07820 7e26912a49cd893b71a010ee788f87f7 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.1E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_07820 7e26912a49cd893b71a010ee788f87f7 309 Pfam PF03466 LysR substrate binding domain 88 297 5.6E-40 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_01405 76f9a5d994f34b49d045e90847716726 372 Gene3D G3DSA:3.40.710.10 30 366 1.7E-82 T 14-10-2018 A4R43_01405 76f9a5d994f34b49d045e90847716726 372 SUPERFAMILY SSF56601 39 354 1.13E-69 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_01405 76f9a5d994f34b49d045e90847716726 372 Pfam PF00144 Beta-lactamase 44 353 3.7E-56 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_00105 3a37da31e92ce29292cc2ed8b1a91192 167 Pfam PF07681 DoxX 31 104 4.5E-7 T 14-10-2018 IPR032808 DoxX family A4R43_05290 5287679cb2cdbcb33de2f174f1d03647 238 Pfam PF00106 short chain dehydrogenase 1 169 8.7E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05290 5287679cb2cdbcb33de2f174f1d03647 238 Gene3D G3DSA:3.40.50.720 1 230 9.5E-47 T 14-10-2018 A4R43_05290 5287679cb2cdbcb33de2f174f1d03647 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 115 143 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_05290 5287679cb2cdbcb33de2f174f1d03647 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 166 4.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05290 5287679cb2cdbcb33de2f174f1d03647 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 102 118 4.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05290 5287679cb2cdbcb33de2f174f1d03647 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 147 4.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05290 5287679cb2cdbcb33de2f174f1d03647 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 56 67 4.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_05290 5287679cb2cdbcb33de2f174f1d03647 238 SUPERFAMILY SSF51735 1 226 2.77E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_36265 4ae2e8fd458717fd8bff19eb1c90e45e 134 SUPERFAMILY SSF82784 1 131 6.54E-21 T 14-10-2018 IPR036102 OsmC/Ohr superfamily A4R43_36265 4ae2e8fd458717fd8bff19eb1c90e45e 134 Gene3D G3DSA:3.30.300.20 2 132 1.7E-20 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta A4R43_36265 4ae2e8fd458717fd8bff19eb1c90e45e 134 Pfam PF02566 OsmC-like protein 29 128 2.6E-15 T 14-10-2018 IPR003718 OsmC/Ohr family A4R43_00715 fa604d0d882883c33f957ac896b61f39 561 SUPERFAMILY SSF51338 17 95 1.06E-10 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_00715 fa604d0d882883c33f957ac896b61f39 561 Gene3D G3DSA:3.20.20.140 77 513 7.9E-113 T 14-10-2018 A4R43_00715 fa604d0d882883c33f957ac896b61f39 561 Gene3D G3DSA:3.10.310.70 95 209 7.9E-113 T 14-10-2018 A4R43_00715 fa604d0d882883c33f957ac896b61f39 561 Gene3D G3DSA:2.30.40.10 25 531 7.9E-113 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_00715 fa604d0d882883c33f957ac896b61f39 561 SUPERFAMILY SSF51556 76 514 2.76E-37 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_00715 fa604d0d882883c33f957ac896b61f39 561 Pfam PF07969 Amidohydrolase family 73 552 9.3E-93 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_09550 60f259b221ca1441e7d6b9b9e9957632 206 SUPERFAMILY SSF46689 5 76 7.7E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_09550 60f259b221ca1441e7d6b9b9e9957632 206 Gene3D G3DSA:1.10.357.10 3 201 3.1E-27 T 14-10-2018 A4R43_09550 60f259b221ca1441e7d6b9b9e9957632 206 SUPERFAMILY SSF48498 95 193 8.22E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_08645 cc0fb078e8f1306286e212cd9fb8b0c5 277 Gene3D G3DSA:3.90.226.10 5 210 8.6E-72 T 14-10-2018 A4R43_08645 cc0fb078e8f1306286e212cd9fb8b0c5 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_08645 cc0fb078e8f1306286e212cd9fb8b0c5 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 265 3.0E-48 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_08645 cc0fb078e8f1306286e212cd9fb8b0c5 277 SUPERFAMILY SSF52096 8 264 2.34E-69 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 SUPERFAMILY SSF48264 43 427 2.62E-85 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 Gene3D G3DSA:1.10.630.10 42 428 7.6E-111 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 370 379 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 368 377 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 116 127 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 182 197 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 165 181 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 301 312 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 377 388 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 347 362 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 319 346 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00359 B-class P450 signature 219 241 1.8E-52 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 Pfam PF00067 Cytochrome P450 72 227 1.6E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 Pfam PF00067 Cytochrome P450 231 398 3.3E-19 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00385 P450 superfamily signature 377 388 9.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00385 P450 superfamily signature 263 280 9.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00385 P450 superfamily signature 368 377 9.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_05625 962a8ee9cef849ae009c5b6cec4ea884 428 PRINTS PR00385 P450 superfamily signature 301 312 9.6E-7 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_06825 e3532afbb4d80a50ea4f3b2e4baee325 312 Gene3D G3DSA:3.40.190.10 114 239 1.4E-62 T 14-10-2018 A4R43_06825 e3532afbb4d80a50ea4f3b2e4baee325 312 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 311 3.0E-29 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_06825 e3532afbb4d80a50ea4f3b2e4baee325 312 Gene3D G3DSA:3.40.190.150 24 304 1.4E-62 T 14-10-2018 A4R43_06825 e3532afbb4d80a50ea4f3b2e4baee325 312 PIRSF PIRSF017082 1 312 3.7E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A4R43_06825 e3532afbb4d80a50ea4f3b2e4baee325 312 SUPERFAMILY SSF53850 108 278 7.19E-6 T 14-10-2018 A4R43_04945 0ce81e90fc4fa2ff029cadcdbdcc2e96 259 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 248 5.0E-72 T 14-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 A4R43_04945 0ce81e90fc4fa2ff029cadcdbdcc2e96 259 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 240 1.5E-73 T 14-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 A4R43_04945 0ce81e90fc4fa2ff029cadcdbdcc2e96 259 SUPERFAMILY SSF100950 5 251 4.55E-64 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_04945 0ce81e90fc4fa2ff029cadcdbdcc2e96 259 Gene3D G3DSA:3.40.50.1360 1 250 1.1E-87 T 14-10-2018 A4R43_00555 646f65ffaf3a80006ed8c725d472463b 398 Pfam PF08811 Protein of unknown function (DUF1800) 13 395 8.3E-87 T 14-10-2018 IPR014917 Protein of unknown function DUF1800 A4R43_36300 2d0e91de28a06261bce6b873400bca4d 190 Pfam PF00857 Isochorismatase family 4 185 5.3E-34 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4R43_36300 2d0e91de28a06261bce6b873400bca4d 190 SUPERFAMILY SSF52499 4 185 1.13E-48 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_36300 2d0e91de28a06261bce6b873400bca4d 190 Gene3D G3DSA:3.40.50.850 3 184 2.9E-62 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4R43_16860 0d0cb65c0fb2d44c9f27ce0924a2efa3 444 Pfam PF03993 Domain of Unknown Function (DUF349) 286 359 1.0E-21 T 14-10-2018 IPR007139 Protein of unknown function DUF349 A4R43_16860 0d0cb65c0fb2d44c9f27ce0924a2efa3 444 Pfam PF03993 Domain of Unknown Function (DUF349) 209 281 1.2E-21 T 14-10-2018 IPR007139 Protein of unknown function DUF349 A4R43_16860 0d0cb65c0fb2d44c9f27ce0924a2efa3 444 Pfam PF03993 Domain of Unknown Function (DUF349) 132 205 1.4E-13 T 14-10-2018 IPR007139 Protein of unknown function DUF349 A4R43_24235 ec97079a108219cddff8ba5671e57797 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 6.3E-13 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_24235 ec97079a108219cddff8ba5671e57797 136 SUPERFAMILY SSF54593 2 134 9.26E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_24235 ec97079a108219cddff8ba5671e57797 136 Gene3D G3DSA:3.10.180.10 2 136 1.0E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_29560 6404bdcc3207b2096c667df2fe995345 203 Gene3D G3DSA:3.90.1200.10 44 200 1.0E-8 T 14-10-2018 A4R43_29560 6404bdcc3207b2096c667df2fe995345 203 Pfam PF01636 Phosphotransferase enzyme family 1 144 2.5E-7 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_29560 6404bdcc3207b2096c667df2fe995345 203 SUPERFAMILY SSF56112 1 156 2.38E-11 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_13205 5e4b2adc080af3d5464a5a35cf536ea3 196 Pfam PF03029 Conserved hypothetical ATP binding protein 22 189 2.6E-27 T 14-10-2018 IPR004130 GPN-loop GTPase A4R43_13205 5e4b2adc080af3d5464a5a35cf536ea3 196 SUPERFAMILY SSF52540 17 188 4.34E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_13205 5e4b2adc080af3d5464a5a35cf536ea3 196 Gene3D G3DSA:3.40.50.300 12 192 4.7E-16 T 14-10-2018 A4R43_06520 a3ddbdb0eee4f875f0c9b549bb0b3c04 167 SUPERFAMILY SSF52540 5 161 1.23E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_06520 a3ddbdb0eee4f875f0c9b549bb0b3c04 167 Gene3D G3DSA:3.40.50.300 4 167 2.5E-25 T 14-10-2018 A4R43_35510 b1de8a9cca311125714cae455a7fef57 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_35510 b1de8a9cca311125714cae455a7fef57 106 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_35510 b1de8a9cca311125714cae455a7fef57 106 Gene3D G3DSA:3.30.70.20 2 106 4.4E-47 T 14-10-2018 A4R43_35510 b1de8a9cca311125714cae455a7fef57 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.0E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4R43_35510 b1de8a9cca311125714cae455a7fef57 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.0E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4R43_35510 b1de8a9cca311125714cae455a7fef57 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.0E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4R43_35510 b1de8a9cca311125714cae455a7fef57 106 SUPERFAMILY SSF54862 3 85 1.76E-21 T 14-10-2018 A4R43_20685 cf60a5e2fa94ad6afbeda292d6cab730 518 SUPERFAMILY SSF52200 17 119 5.23E-6 T 14-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily A4R43_20685 cf60a5e2fa94ad6afbeda292d6cab730 518 Pfam PF13676 TIR domain 17 131 7.4E-14 T 14-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 A4R43_20685 cf60a5e2fa94ad6afbeda292d6cab730 518 Gene3D G3DSA:3.40.50.10140 16 153 1.1E-10 T 14-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily A4R43_22760 2f723c3e4dc690a090c5bf6a57729d6e 172 Gene3D G3DSA:1.10.10.10 4 79 4.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22760 2f723c3e4dc690a090c5bf6a57729d6e 172 SUPERFAMILY SSF46785 10 80 1.79E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_22760 2f723c3e4dc690a090c5bf6a57729d6e 172 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 3.9E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_22760 2f723c3e4dc690a090c5bf6a57729d6e 172 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 3.9E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_22760 2f723c3e4dc690a090c5bf6a57729d6e 172 Pfam PF12840 Helix-turn-helix domain 10 64 1.4E-15 T 14-10-2018 A4R43_22760 2f723c3e4dc690a090c5bf6a57729d6e 172 SMART SM00418 8 101 7.9E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_20220 174a96fc7e13be56f4bef1e11ada07c3 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 12 251 3.1E-107 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A4R43_20220 174a96fc7e13be56f4bef1e11ada07c3 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 252 427 7.5E-83 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A4R43_20220 174a96fc7e13be56f4bef1e11ada07c3 428 PIRSF PIRSF001362 2 428 5.6E-239 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A4R43_20220 174a96fc7e13be56f4bef1e11ada07c3 428 Gene3D G3DSA:3.20.20.60 9 411 4.3E-169 T 14-10-2018 A4R43_20220 174a96fc7e13be56f4bef1e11ada07c3 428 ProSitePatterns PS00161 Isocitrate lyase signature. 189 194 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 A4R43_20220 174a96fc7e13be56f4bef1e11ada07c3 428 Pfam PF00463 Isocitrate lyase family 252 426 1.1E-43 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A4R43_20220 174a96fc7e13be56f4bef1e11ada07c3 428 Pfam PF00463 Isocitrate lyase family 15 251 3.2E-53 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A4R43_20220 174a96fc7e13be56f4bef1e11ada07c3 428 SUPERFAMILY SSF51621 9 427 1.12E-158 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_16385 2b9ccc65967f33d6ffaa38a1b1d82a9a 132 Gene3D G3DSA:3.30.530.20 12 77 3.3E-5 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_16385 2b9ccc65967f33d6ffaa38a1b1d82a9a 132 SUPERFAMILY SSF55961 9 124 1.19E-8 T 14-10-2018 A4R43_38865 4221c6261be820e2e240d1f06c3d4681 200 SUPERFAMILY SSF51161 33 194 8.92E-8 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_38865 4221c6261be820e2e240d1f06c3d4681 200 Gene3D G3DSA:2.160.10.10 15 200 6.0E-6 T 14-10-2018 A4R43_10555 4c83eea06bdfa67ee28e1fca7b023733 141 SUPERFAMILY SSF54427 8 141 1.32E-23 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_10555 4c83eea06bdfa67ee28e1fca7b023733 141 Gene3D G3DSA:3.10.450.50 1 141 4.7E-26 T 14-10-2018 A4R43_10555 4c83eea06bdfa67ee28e1fca7b023733 141 Pfam PF12680 SnoaL-like domain 32 127 2.8E-12 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_12840 7666d59c14a3bc2fa2ec5e25d3629a6c 264 Pfam PF12697 Alpha/beta hydrolase family 30 257 2.1E-25 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12840 7666d59c14a3bc2fa2ec5e25d3629a6c 264 SUPERFAMILY SSF53474 4 260 6.57E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12840 7666d59c14a3bc2fa2ec5e25d3629a6c 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 5.1E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12840 7666d59c14a3bc2fa2ec5e25d3629a6c 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 210 224 5.1E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12840 7666d59c14a3bc2fa2ec5e25d3629a6c 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 5.1E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12840 7666d59c14a3bc2fa2ec5e25d3629a6c 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 5.1E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_12840 7666d59c14a3bc2fa2ec5e25d3629a6c 264 Gene3D G3DSA:3.40.50.1820 1 262 6.1E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06000 295d381c743e20fd32d70da549e274c2 274 PIRSF PIRSF006241 8 272 6.6E-75 T 14-10-2018 IPR026040 Hydroxypyruvate isomerase-like A4R43_06000 295d381c743e20fd32d70da549e274c2 274 SUPERFAMILY SSF51658 13 268 9.3E-64 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_06000 295d381c743e20fd32d70da549e274c2 274 Gene3D G3DSA:3.20.20.150 6 272 7.6E-70 T 14-10-2018 A4R43_06000 295d381c743e20fd32d70da549e274c2 274 Pfam PF01261 Xylose isomerase-like TIM barrel 29 228 5.4E-30 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 SUPERFAMILY SSF100934 508 574 6.28E-5 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 Pfam PF00012 Hsp70 protein 79 577 1.6E-218 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 114 134 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 362 381 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 307 323 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 339 359 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 174 184 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 PRINTS PR00301 70kDa heat shock protein signature 443 459 1.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 Gene3D G3DSA:3.90.640.10 200 288 9.2E-147 T 14-10-2018 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 SUPERFAMILY SSF100920 358 514 6.41E-60 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 Gene3D G3DSA:3.30.420.40 162 339 9.2E-147 T 14-10-2018 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 Gene3D G3DSA:1.20.1270.10 481 581 2.3E-31 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 SUPERFAMILY SSF53067 162 356 2.95E-63 T 14-10-2018 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 Gene3D G3DSA:3.30.420.40 5 350 9.2E-147 T 14-10-2018 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 615 36.062 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 Gene3D G3DSA:2.60.34.10 351 478 4.0E-59 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 577 1.0E-276 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 SUPERFAMILY SSF53067 4 160 2.73E-57 T 14-10-2018 A4R43_31395 aaf1d73028c2150a79781f5b71a35c45 626 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4R43_02945 63702616c9478ad8b1363fc61446147f 356 PIRSF PIRSF005508 4 356 3.5E-139 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A4R43_02945 63702616c9478ad8b1363fc61446147f 356 Pfam PF01758 Sodium Bile acid symporter family 60 256 1.1E-64 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A4R43_02945 63702616c9478ad8b1363fc61446147f 356 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 15 343 1.6E-133 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A4R43_02945 63702616c9478ad8b1363fc61446147f 356 Gene3D G3DSA:1.20.1530.20 10 349 7.6E-28 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily A4R43_00130 112072400b33645c7b9f916aa6cfaa1e 150 Gene3D G3DSA:2.60.120.10 2 149 8.3E-27 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_00130 112072400b33645c7b9f916aa6cfaa1e 150 SMART SM00835 6 131 0.0096 T 14-10-2018 IPR006045 Cupin 1 GO:0045735 A4R43_00130 112072400b33645c7b9f916aa6cfaa1e 150 Pfam PF07883 Cupin domain 41 105 4.1E-16 T 14-10-2018 IPR013096 Cupin 2, conserved barrel A4R43_00130 112072400b33645c7b9f916aa6cfaa1e 150 SUPERFAMILY SSF51182 11 133 1.49E-23 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_08650 acd95169d566c1135a4f851b5d33d76b 484 SUPERFAMILY SSF53720 12 476 7.07E-144 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_08650 acd95169d566c1135a4f851b5d33d76b 484 Pfam PF00171 Aldehyde dehydrogenase family 23 473 5.9E-144 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_08650 acd95169d566c1135a4f851b5d33d76b 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_08650 acd95169d566c1135a4f851b5d33d76b 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4R43_08650 acd95169d566c1135a4f851b5d33d76b 484 Gene3D G3DSA:3.40.309.10 254 441 1.8E-145 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_08650 acd95169d566c1135a4f851b5d33d76b 484 Gene3D G3DSA:3.40.605.10 26 459 1.8E-145 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_28460 26500f1f4be096c259a3d725985a15eb 159 SMART SM00894 67 104 0.0094 T 14-10-2018 IPR008613 Excalibur calcium-binding domain A4R43_28460 26500f1f4be096c259a3d725985a15eb 159 Pfam PF05901 Excalibur calcium-binding domain 68 104 8.5E-5 T 14-10-2018 IPR008613 Excalibur calcium-binding domain A4R43_15510 9e0f6d6f9e23397d81560191b7150211 385 SUPERFAMILY SSF53300 205 367 1.59E-21 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_15510 9e0f6d6f9e23397d81560191b7150211 385 Gene3D G3DSA:3.40.50.410 200 354 8.8E-7 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4R43_15510 9e0f6d6f9e23397d81560191b7150211 385 SMART SM00327 206 365 0.0018 T 14-10-2018 IPR002035 von Willebrand factor, type A A4R43_15510 9e0f6d6f9e23397d81560191b7150211 385 Pfam PF05762 VWA domain containing CoxE-like protein 146 362 3.5E-55 T 14-10-2018 IPR008912 Uncharacterised protein family CoxE-like A4R43_13035 b37049bf7c8d9b106e318edf699ab33c 293 SUPERFAMILY SSF53474 2 288 1.94E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13035 b37049bf7c8d9b106e318edf699ab33c 293 Gene3D G3DSA:3.40.50.1820 5 253 1.1E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13035 b37049bf7c8d9b106e318edf699ab33c 293 Pfam PF12146 Serine aminopeptidase, S33 32 252 1.6E-11 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 A4R43_13035 b37049bf7c8d9b106e318edf699ab33c 293 Gene3D G3DSA:1.10.10.800 141 216 1.1E-38 T 14-10-2018 A4R43_10085 681307439ee4651ade5f44992c92738d 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 57 6.6E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_10085 681307439ee4651ade5f44992c92738d 184 Gene3D G3DSA:1.10.357.10 2 182 2.0E-24 T 14-10-2018 A4R43_10085 681307439ee4651ade5f44992c92738d 184 SUPERFAMILY SSF46689 3 75 1.28E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_30135 e14cfe1d8b98a282fcdb92040f99818a 476 Pfam PF02470 MlaD protein 44 119 1.4E-14 T 14-10-2018 IPR003399 Mce/MlaD A4R43_23905 caf914a6210deaba3c3f91f21a7c7982 368 Gene3D G3DSA:1.10.530.10 102 268 2.4E-7 T 14-10-2018 A4R43_23905 caf914a6210deaba3c3f91f21a7c7982 368 SUPERFAMILY SSF53955 94 261 2.67E-34 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_23905 caf914a6210deaba3c3f91f21a7c7982 368 Pfam PF13406 Transglycosylase SLT domain 181 225 4.6E-6 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 A4R43_36860 5dc53d3fc55b94efe0f2171eaeb9b278 114 Pfam PF01638 HxlR-like helix-turn-helix 18 100 1.0E-25 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_36860 5dc53d3fc55b94efe0f2171eaeb9b278 114 Gene3D G3DSA:1.10.10.10 2 106 1.0E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_36860 5dc53d3fc55b94efe0f2171eaeb9b278 114 SUPERFAMILY SSF46785 5 100 3.47E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 SUPERFAMILY SSF51905 228 422 1.16E-8 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 40 406 4.4E-8 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 Gene3D G3DSA:3.50.50.60 114 317 2.3E-13 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 SUPERFAMILY SSF51905 35 258 3.48E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 Gene3D G3DSA:3.50.50.60 22 100 7.8E-8 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 62 1.9E-8 T 14-10-2018 A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 189 198 1.9E-8 T 14-10-2018 A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 388 395 1.9E-8 T 14-10-2018 A4R43_37375 6ecb0bd54b64dc6cdbf19e82cae4c658 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 227 252 1.9E-8 T 14-10-2018 A4R43_16220 1ddcf4411d20c6c6f046965f2daa25a9 117 Pfam PF12823 Domain of unknown function (DUF3817) 22 108 5.1E-25 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A4R43_16220 1ddcf4411d20c6c6f046965f2daa25a9 117 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 25 107 2.9E-28 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A4R43_12385 b48445853efd6a1e6758f1671da249bf 406 SUPERFAMILY SSF103473 17 397 1.27E-48 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_12385 b48445853efd6a1e6758f1671da249bf 406 Pfam PF07690 Major Facilitator Superfamily 28 338 4.1E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_12385 b48445853efd6a1e6758f1671da249bf 406 Gene3D G3DSA:1.20.1250.20 17 203 3.2E-22 T 14-10-2018 A4R43_12385 b48445853efd6a1e6758f1671da249bf 406 Gene3D G3DSA:1.20.1250.20 214 397 9.5E-11 T 14-10-2018 A4R43_21680 0099231517c46393c8c57ff03033134b 325 Pfam PF04545 Sigma-70, region 4 125 172 7.1E-9 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4R43_21680 0099231517c46393c8c57ff03033134b 325 Gene3D G3DSA:1.10.10.10 122 176 2.4E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_21680 0099231517c46393c8c57ff03033134b 325 SUPERFAMILY SSF88946 17 81 7.46E-5 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_21680 0099231517c46393c8c57ff03033134b 325 SUPERFAMILY SSF88659 123 177 3.74E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_21985 d71db7fbed6cc9ff03c2b8e61cdfdfca 299 PIRSF PIRSF003097 1 299 8.1E-76 T 14-10-2018 IPR004513 Cell division protein FtsX GO:0016021 A4R43_21985 d71db7fbed6cc9ff03c2b8e61cdfdfca 299 Pfam PF02687 FtsX-like permease family 203 288 9.1E-6 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_21985 d71db7fbed6cc9ff03c2b8e61cdfdfca 299 Gene3D G3DSA:3.30.70.3040 43 159 2.9E-34 T 14-10-2018 A4R43_06350 7e49014bca436eb02de2cceca344980f 291 Gene3D G3DSA:1.10.3720.10 3 282 2.0E-60 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06350 7e49014bca436eb02de2cceca344980f 291 SUPERFAMILY SSF161098 7 291 9.81E-52 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06350 7e49014bca436eb02de2cceca344980f 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 284 3.6E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_18375 27b73df86ef905af3c1e5a20071dc13f 295 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 250 276 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 A4R43_18375 27b73df86ef905af3c1e5a20071dc13f 295 Pfam PF01148 Cytidylyltransferase family 38 291 9.4E-55 T 14-10-2018 A4R43_31050 9303ea118085d7eedf34de9b79461fc9 119 Gene3D G3DSA:3.30.70.1060 2 116 5.5E-27 T 14-10-2018 A4R43_31050 9303ea118085d7eedf34de9b79461fc9 119 SUPERFAMILY SSF54909 6 111 2.25E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_31050 9303ea118085d7eedf34de9b79461fc9 119 Pfam PF03795 YCII-related domain 12 113 4.2E-15 T 14-10-2018 IPR005545 YCII-related A4R43_36475 8e9bab2cf50545211fdd4aebc559d515 197 Pfam PF02698 DUF218 domain 40 156 2.7E-17 T 14-10-2018 IPR003848 Domain of unknown function DUF218 A4R43_32255 d084e05b0e8bd3f8f60ea82e954a92da 272 SUPERFAMILY SSF46894 1 79 1.5E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_32255 d084e05b0e8bd3f8f60ea82e954a92da 272 Pfam PF03704 Bacterial transcriptional activator domain 108 253 1.1E-42 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_32255 d084e05b0e8bd3f8f60ea82e954a92da 272 SUPERFAMILY SSF48452 106 269 2.81E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32255 d084e05b0e8bd3f8f60ea82e954a92da 272 SMART SM00862 15 101 1.7E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_32255 d084e05b0e8bd3f8f60ea82e954a92da 272 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 77 8.2E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_32255 d084e05b0e8bd3f8f60ea82e954a92da 272 Gene3D G3DSA:1.10.10.10 1 102 3.4E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_32255 d084e05b0e8bd3f8f60ea82e954a92da 272 Gene3D G3DSA:1.25.40.10 107 266 7.2E-48 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_32255 d084e05b0e8bd3f8f60ea82e954a92da 272 SMART SM01043 108 253 1.5E-49 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_23485 b71157ab77c49e9feb92903618e9039b 332 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 24 301 1.9E-97 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A4R43_23485 b71157ab77c49e9feb92903618e9039b 332 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 22 305 36.835 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A4R43_23485 b71157ab77c49e9feb92903618e9039b 332 Gene3D G3DSA:3.40.1010.20 118 214 4.3E-110 T 14-10-2018 A4R43_23485 b71157ab77c49e9feb92903618e9039b 332 Gene3D G3DSA:3.40.1010.20 27 300 4.3E-110 T 14-10-2018 A4R43_23485 b71157ab77c49e9feb92903618e9039b 332 Gene3D G3DSA:3.40.50.11270 33 117 4.3E-110 T 14-10-2018 A4R43_23485 b71157ab77c49e9feb92903618e9039b 332 Pfam PF02401 LytB protein 24 301 1.9E-89 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A4R43_28060 22c07a390648750939a2a6d4540e4ab7 187 Pfam PF10759 Protein of unknown function (DUF2587) 37 187 1.3E-78 T 14-10-2018 IPR019695 Bacterial proteasome activator GO:0061136 A4R43_41120 9cb87c09fd69688afb421f8bd1d5078f 439 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 407 1.6E-93 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4R43_41120 9cb87c09fd69688afb421f8bd1d5078f 439 Pfam PF01554 MatE 20 180 2.5E-26 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4R43_41120 9cb87c09fd69688afb421f8bd1d5078f 439 Pfam PF01554 MatE 237 385 1.3E-16 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4R43_41120 9cb87c09fd69688afb421f8bd1d5078f 439 PIRSF PIRSF006603 4 438 6.2E-52 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4R43_34740 b655bdf9d9d9fe61ea23385495e6d6aa 138 SUPERFAMILY SSF81343 10 133 1.63E-31 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34740 b655bdf9d9d9fe61ea23385495e6d6aa 138 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 9 119 1.5E-15 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_34740 b655bdf9d9d9fe61ea23385495e6d6aa 138 Gene3D G3DSA:1.20.1300.10 17 131 2.7E-23 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_39755 01d02d80f76f7d9cff43ae8aca50730c 221 Gene3D G3DSA:2.40.260.10 69 220 2.9E-14 T 14-10-2018 IPR023365 Sortase domain superfamily A4R43_39755 01d02d80f76f7d9cff43ae8aca50730c 221 SUPERFAMILY SSF63817 68 218 2.94E-11 T 14-10-2018 IPR023365 Sortase domain superfamily A4R43_39755 01d02d80f76f7d9cff43ae8aca50730c 221 Pfam PF04203 Sortase family 118 218 1.7E-9 T 14-10-2018 IPR005754 Sortase family A4R43_38705 64153fe89650013ce586e84eaf01dab7 478 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4R43_38705 64153fe89650013ce586e84eaf01dab7 478 SUPERFAMILY SSF103473 12 462 4.19E-59 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_38705 64153fe89650013ce586e84eaf01dab7 478 Gene3D G3DSA:1.20.1250.20 279 466 8.1E-17 T 14-10-2018 A4R43_38705 64153fe89650013ce586e84eaf01dab7 478 Pfam PF07690 Major Facilitator Superfamily 29 417 7.6E-49 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_38705 64153fe89650013ce586e84eaf01dab7 478 Gene3D G3DSA:1.20.1720.10 21 226 8.3E-41 T 14-10-2018 A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 Gene3D G3DSA:3.40.1410.10 82 248 1.0E-49 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 Gene3D G3DSA:1.10.10.10 4 81 2.4E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 SUPERFAMILY SSF46785 2 82 4.59E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 Pfam PF07702 UTRA domain 115 245 8.6E-32 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 SMART SM00345 14 73 6.2E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.4E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 SUPERFAMILY SSF64288 61 251 6.77E-36 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 5.2E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 5.2E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_31520 0c2f38e4f1122e5ae7fc30536d868a81 253 SMART SM00866 105 245 2.1E-26 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_33635 5792fdb353146d74e4fab7d941436c38 422 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 292 2.2E-56 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_33635 5792fdb353146d74e4fab7d941436c38 422 Pfam PF02470 MlaD protein 39 114 6.0E-14 T 14-10-2018 IPR003399 Mce/MlaD A4R43_38300 53afbcb28627219fefbecd74447bee9c 477 PIRSF PIRSF006060 27 477 6.3E-92 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_38300 53afbcb28627219fefbecd74447bee9c 477 Pfam PF13520 Amino acid permease 41 444 1.6E-54 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_38300 53afbcb28627219fefbecd74447bee9c 477 Gene3D G3DSA:1.20.1740.10 36 476 3.0E-120 T 14-10-2018 A4R43_34560 95cbd70102538b7128deb75fb1a27a15 390 Gene3D G3DSA:1.20.1250.20 3 374 1.7E-46 T 14-10-2018 A4R43_34560 95cbd70102538b7128deb75fb1a27a15 390 SUPERFAMILY SSF103473 3 375 3.14E-56 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_34560 95cbd70102538b7128deb75fb1a27a15 390 Pfam PF07690 Major Facilitator Superfamily 8 342 6.1E-40 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_03750 8c699007c502ceac8fe10737c11b8804 349 SUPERFAMILY SSF51679 1 348 5.89E-61 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_03750 8c699007c502ceac8fe10737c11b8804 349 Gene3D G3DSA:3.20.20.30 1 349 1.6E-75 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_03750 8c699007c502ceac8fe10737c11b8804 349 Pfam PF00296 Luciferase-like monooxygenase 11 308 2.9E-56 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_10660 0b438e918732e753bd94bc65a4163d07 116 Pfam PF04237 YjbR 24 100 2.7E-11 T 14-10-2018 IPR007351 Uncharacterised protein YjbR A4R43_10660 0b438e918732e753bd94bc65a4163d07 116 SUPERFAMILY SSF142906 23 107 2.22E-8 T 14-10-2018 IPR038056 YjbR-like superfamily A4R43_03550 e7fc1cab432a8608995b0552ffbf4417 169 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 154 6.0E-51 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_03550 e7fc1cab432a8608995b0552ffbf4417 169 Gene3D G3DSA:3.30.1060.10 1 167 1.2E-69 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_03550 e7fc1cab432a8608995b0552ffbf4417 169 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 160 34.37 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_03550 e7fc1cab432a8608995b0552ffbf4417 169 SUPERFAMILY SSF55068 3 162 4.71E-65 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_03550 e7fc1cab432a8608995b0552ffbf4417 169 Pfam PF01625 Peptide methionine sulfoxide reductase 8 154 7.8E-57 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4R43_38115 1cb76f95842dacdd555fe20dd219cc96 616 Pfam PF04294 VanW like protein 409 540 5.0E-41 T 14-10-2018 IPR007391 Vancomycin resistance VanW A4R43_38115 1cb76f95842dacdd555fe20dd219cc96 616 Pfam PF12229 Putative peptidoglycan binding domain 263 364 8.4E-9 T 14-10-2018 IPR022029 Putative peptidoglycan binding domain A4R43_05590 d9e5049aa09345896709611647c57d56 99 Gene3D G3DSA:3.40.630.30 6 96 7.4E-22 T 14-10-2018 A4R43_05590 d9e5049aa09345896709611647c57d56 99 SUPERFAMILY SSF55729 7 94 2.42E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_05590 d9e5049aa09345896709611647c57d56 99 Pfam PF14542 GCN5-related N-acetyl-transferase 15 91 1.6E-21 T 14-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase A4R43_22510 68b7190377f81857df3cb19e03860828 222 SUPERFAMILY SSF56037 46 189 1.78E-30 T 14-10-2018 A4R43_22510 68b7190377f81857df3cb19e03860828 222 SMART SM00873 56 203 8.6E-13 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4R43_22510 68b7190377f81857df3cb19e03860828 222 Pfam PF03483 B3/4 domain 57 189 2.0E-22 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4R43_22510 68b7190377f81857df3cb19e03860828 222 Gene3D G3DSA:3.50.40.10 59 198 2.2E-6 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A4R43_25720 aaa7b093c9e9d289ba247654cf8b542b 219 SMART SM00862 145 217 2.1E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25720 aaa7b093c9e9d289ba247654cf8b542b 219 SUPERFAMILY SSF52172 2 171 1.51E-33 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_25720 aaa7b093c9e9d289ba247654cf8b542b 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 1.7E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_25720 aaa7b093c9e9d289ba247654cf8b542b 219 SMART SM00448 1 112 2.0E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_25720 aaa7b093c9e9d289ba247654cf8b542b 219 Gene3D G3DSA:3.40.50.2300 1 120 3.7E-30 T 14-10-2018 A4R43_25720 aaa7b093c9e9d289ba247654cf8b542b 219 Gene3D G3DSA:1.10.10.10 122 218 2.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_25720 aaa7b093c9e9d289ba247654cf8b542b 219 Pfam PF00072 Response regulator receiver domain 3 113 1.5E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_17425 6325dafb91ede846b5a426c4b4d20157 422 Pfam PF13185 GAF domain 30 174 2.4E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_17425 6325dafb91ede846b5a426c4b4d20157 422 SUPERFAMILY SSF81606 220 420 1.05E-8 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_17425 6325dafb91ede846b5a426c4b4d20157 422 SUPERFAMILY SSF55781 31 182 2.18E-14 T 14-10-2018 A4R43_17425 6325dafb91ede846b5a426c4b4d20157 422 SMART SM00065 30 183 2.7E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_17425 6325dafb91ede846b5a426c4b4d20157 422 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 230 420 2.2E-43 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_17425 6325dafb91ede846b5a426c4b4d20157 422 Gene3D G3DSA:3.30.450.40 17 177 9.9E-20 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_17425 6325dafb91ede846b5a426c4b4d20157 422 Gene3D G3DSA:3.60.40.10 178 419 4.6E-54 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_17425 6325dafb91ede846b5a426c4b4d20157 422 SMART SM00331 205 420 4.9E-33 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A4R43_25710 b1f9d6706c1655d709c44db1997fd8c4 367 Gene3D G3DSA:1.10.101.10 123 185 2.7E-8 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_25710 b1f9d6706c1655d709c44db1997fd8c4 367 SUPERFAMILY SSF47090 131 182 2.55E-8 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_25710 b1f9d6706c1655d709c44db1997fd8c4 367 Gene3D G3DSA:2.40.420.20 291 366 3.6E-9 T 14-10-2018 A4R43_25710 b1f9d6706c1655d709c44db1997fd8c4 367 Pfam PF01471 Putative peptidoglycan binding domain 132 180 3.5E-8 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_12475 8a3ad295ee6719ae6ed1dda167613d2f 228 Pfam PF00975 Thioesterase domain 5 223 3.1E-38 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_12475 8a3ad295ee6719ae6ed1dda167613d2f 228 Gene3D G3DSA:3.40.50.1820 3 227 5.0E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12475 8a3ad295ee6719ae6ed1dda167613d2f 228 SUPERFAMILY SSF53474 4 224 6.15E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_19520 1dc8b8c98c2c8c7296aaed52965f0215 77 SUPERFAMILY SSF54909 2 75 3.35E-14 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_19520 1dc8b8c98c2c8c7296aaed52965f0215 77 Gene3D G3DSA:3.30.70.920 2 73 1.3E-18 T 14-10-2018 A4R43_19520 1dc8b8c98c2c8c7296aaed52965f0215 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 1.5E-12 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4R43_37555 efbf82f4045ed3ee4ea6a0795cab0a39 1034 Pfam PF13569 Domain of unknown function (DUF4132) 762 944 7.0E-58 T 14-10-2018 IPR025406 Domain of unknown function DUF4132 A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 4.1E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 4.1E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 4.1E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 4.1E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 4.1E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 Pfam PF00106 short chain dehydrogenase 13 198 3.2E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 Gene3D G3DSA:3.40.50.720 9 284 3.2E-65 T 14-10-2018 A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 2.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 2.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 2.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_21045 79cc01ca54af7daf9377d63c9c42f4ea 303 SUPERFAMILY SSF51735 10 261 4.35E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 Gene3D G3DSA:3.20.20.120 102 344 1.7E-147 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 SUPERFAMILY SSF51604 95 360 1.97E-80 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 5 107 9.4E-27 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 SUPERFAMILY SSF54826 1 112 3.84E-32 T 14-10-2018 A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 SMART SM00922 125 230 2.6E-23 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 Pfam PF13378 Enolase C-terminal domain-like 129 355 1.3E-64 T 14-10-2018 IPR029065 Enolase C-terminal domain-like A4R43_40010 296b426ee2b2ff862f6006989c355dc9 382 Gene3D G3DSA:3.30.390.10 11 374 1.7E-147 T 14-10-2018 IPR029017 Enolase-like, N-terminal A4R43_15775 0c302d60b198d8260e20a672d5541246 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 303 2.7E-14 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_15775 0c302d60b198d8260e20a672d5541246 340 Pfam PF01548 Transposase 4 154 2.0E-25 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_13965 0c302d60b198d8260e20a672d5541246 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 303 2.7E-14 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4R43_13965 0c302d60b198d8260e20a672d5541246 340 Pfam PF01548 Transposase 4 154 2.0E-25 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 SUPERFAMILY SSF89550 6 276 2.55E-29 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 Gene3D G3DSA:3.20.20.140 1 296 2.7E-97 T 14-10-2018 A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 SMART SM00481 7 74 5.2E-33 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 322 761 4.7E-162 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 Pfam PF02811 PHP domain 8 200 1.6E-50 T 14-10-2018 IPR004013 PHP domain GO:0003824 A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 Gene3D G3DSA:1.10.10.1600 455 544 2.3E-15 T 14-10-2018 A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 Pfam PF14579 Helix-hairpin-helix motif 841 927 1.4E-25 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1072 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4R43_17930 ae94fe8085d72cca0755fa44b96ae329 1196 Gene3D G3DSA:1.10.150.870 816 918 1.2E-5 T 14-10-2018 A4R43_13830 53d5b625ca7248188d48e3bd87077341 359 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 19 359 45.647 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4R43_13830 53d5b625ca7248188d48e3bd87077341 359 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 22 358 2.7E-120 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4R43_13830 53d5b625ca7248188d48e3bd87077341 359 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 35 44 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4R43_13830 53d5b625ca7248188d48e3bd87077341 359 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 152 168 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4R43_13830 53d5b625ca7248188d48e3bd87077341 359 Gene3D G3DSA:3.20.20.210 9 359 4.0E-142 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_13830 53d5b625ca7248188d48e3bd87077341 359 SUPERFAMILY SSF51726 21 358 2.75E-103 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_13830 53d5b625ca7248188d48e3bd87077341 359 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 19 358 3.0E-127 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4R43_25475 a37b52f46d29ef5f11e8d94e3b7429c6 417 Gene3D G3DSA:3.90.70.10 242 416 4.1E-11 T 14-10-2018 A4R43_25475 a37b52f46d29ef5f11e8d94e3b7429c6 417 Pfam PF13529 Peptidase_C39 like family 221 372 4.7E-31 T 14-10-2018 IPR039564 Peptidase C39-like A4R43_13780 5b5306fc9b0231d035933196d6b21ef4 140 Pfam PF01641 SelR domain 17 137 3.1E-52 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A4R43_13780 5b5306fc9b0231d035933196d6b21ef4 140 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 13 139 6.5E-49 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A4R43_13780 5b5306fc9b0231d035933196d6b21ef4 140 Gene3D G3DSA:2.170.150.20 2 140 4.2E-59 T 14-10-2018 A4R43_13780 5b5306fc9b0231d035933196d6b21ef4 140 SUPERFAMILY SSF51316 12 139 1.31E-55 T 14-10-2018 IPR011057 Mss4-like superfamily A4R43_06610 deb90b2b399256383f33c6d2008e754e 433 Pfam PF07690 Major Facilitator Superfamily 52 382 5.0E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_06610 deb90b2b399256383f33c6d2008e754e 433 SUPERFAMILY SSF103473 8 423 1.28E-59 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_06610 deb90b2b399256383f33c6d2008e754e 433 Gene3D G3DSA:1.20.1250.20 12 426 1.0E-61 T 14-10-2018 A4R43_29680 19938c77a624409f277d01b8f6c4225a 152 Pfam PF07811 TadE-like protein 14 56 1.3E-9 T 14-10-2018 IPR012495 TadE-like A4R43_03520 94366bf4cd3eec6a02ca241a01ee0638 143 Pfam PF00583 Acetyltransferase (GNAT) family 44 121 1.3E-12 T 14-10-2018 IPR000182 GNAT domain A4R43_03520 94366bf4cd3eec6a02ca241a01ee0638 143 Gene3D G3DSA:3.40.630.30 39 143 3.9E-27 T 14-10-2018 A4R43_03520 94366bf4cd3eec6a02ca241a01ee0638 143 SUPERFAMILY SSF55729 16 143 3.21E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_03565 ced8426ef42a482e4344093a09b395af 174 Pfam PF13302 Acetyltransferase (GNAT) domain 4 146 1.1E-21 T 14-10-2018 IPR000182 GNAT domain A4R43_03565 ced8426ef42a482e4344093a09b395af 174 Gene3D G3DSA:3.40.630.30 1 164 1.7E-29 T 14-10-2018 A4R43_03565 ced8426ef42a482e4344093a09b395af 174 SUPERFAMILY SSF55729 2 155 1.48E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_39505 59ead2ac5743c4c92980e12615f79880 306 PIRSF PIRSF002936 7 306 2.5E-133 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4R43_39505 59ead2ac5743c4c92980e12615f79880 306 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 36 260 5.7E-46 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A4R43_39505 59ead2ac5743c4c92980e12615f79880 306 SUPERFAMILY SSF52402 10 214 1.12E-64 T 14-10-2018 A4R43_39505 59ead2ac5743c4c92980e12615f79880 306 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 15 306 1.9E-139 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4R43_39505 59ead2ac5743c4c92980e12615f79880 306 Gene3D G3DSA:3.40.50.620 13 216 1.7E-57 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_10345 1e0461fb1fe301d9c5b1f5f389170ed3 212 PIRSF PIRSF006324 1 211 2.4E-56 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_10345 1e0461fb1fe301d9c5b1f5f389170ed3 212 Pfam PF01810 LysE type translocator 15 208 4.8E-41 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_07145 384e474d7f4ed48f6cdf7ff23e6a2248 466 Pfam PF00561 alpha/beta hydrolase fold 69 435 5.6E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_07145 384e474d7f4ed48f6cdf7ff23e6a2248 466 SUPERFAMILY SSF53474 49 435 2.65E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03135 cdbc456a437e8ecb5390f92b969e6967 312 Pfam PF04199 Putative cyclase 87 241 5.6E-23 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_03135 cdbc456a437e8ecb5390f92b969e6967 312 Gene3D G3DSA:3.50.30.50 57 312 1.2E-24 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_03135 cdbc456a437e8ecb5390f92b969e6967 312 SUPERFAMILY SSF102198 93 311 2.75E-22 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_03615 cc701e05f398600ae82b2f4cd64657fe 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 305 1.9E-37 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_03615 cc701e05f398600ae82b2f4cd64657fe 309 SUPERFAMILY SSF161098 89 290 2.29E-15 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_03615 cc701e05f398600ae82b2f4cd64657fe 309 Gene3D G3DSA:1.10.3720.10 84 298 1.5E-21 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_25455 7500323c42d69ae3f29837ed9febe469 103 Gene3D G3DSA:1.10.8.50 1 103 1.5E-32 T 14-10-2018 A4R43_36670 b25941d849e933e1bd6ab062e76d60b8 204 Pfam PF06810 Phage minor structural protein GP20 79 176 1.4E-7 T 14-10-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069 A4R43_02305 678d8a8ac812c4d8b3d150e62eca0eb1 263 SMART SM00824 Thioesterase 31 249 1.2E-5 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4R43_02305 678d8a8ac812c4d8b3d150e62eca0eb1 263 Gene3D G3DSA:3.40.50.1820 27 258 6.1E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02305 678d8a8ac812c4d8b3d150e62eca0eb1 263 SUPERFAMILY SSF53474 10 249 5.13E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02305 678d8a8ac812c4d8b3d150e62eca0eb1 263 Pfam PF00975 Thioesterase domain 29 244 2.0E-41 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_35275 a4a780867ff4a88ccf4de530f58338ad 168 Pfam PF04138 GtrA-like protein 13 143 2.1E-17 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.9E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.9E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.9E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.9E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.9E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.9E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_07370 78333d03e1b093517d41351eaef389cb 264 Gene3D G3DSA:3.40.50.720 11 248 1.4E-74 T 14-10-2018 A4R43_07370 78333d03e1b093517d41351eaef389cb 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 180 8.4E-4 T 14-10-2018 A4R43_07370 78333d03e1b093517d41351eaef389cb 264 SUPERFAMILY SSF51735 13 247 9.87E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 8.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.8E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07370 78333d03e1b093517d41351eaef389cb 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 246 3.0E-61 T 14-10-2018 A4R43_27710 31c0545b83de6f97f1cc4e8e008a6f1d 220 SUPERFAMILY SSF48498 82 195 1.16E-15 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_27710 31c0545b83de6f97f1cc4e8e008a6f1d 220 Gene3D G3DSA:1.10.357.10 8 203 5.2E-44 T 14-10-2018 A4R43_27710 31c0545b83de6f97f1cc4e8e008a6f1d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_27710 31c0545b83de6f97f1cc4e8e008a6f1d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_27710 31c0545b83de6f97f1cc4e8e008a6f1d 220 SUPERFAMILY SSF46689 13 87 9.98E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_27710 31c0545b83de6f97f1cc4e8e008a6f1d 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.9E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_32055 8040f6c5a4f825e29c72b1a4ff444aea 204 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 40 203 32.339 T 14-10-2018 IPR022939 Uncharacterised protein family UPF0678 A4R43_32055 8040f6c5a4f825e29c72b1a4ff444aea 204 SUPERFAMILY SSF50814 43 202 5.11E-42 T 14-10-2018 IPR012674 Calycin A4R43_32055 8040f6c5a4f825e29c72b1a4ff444aea 204 Pfam PF08768 Domain of unknown function (DUF1794) 48 201 1.1E-47 T 14-10-2018 IPR014878 Domain of unknown function DUF1794 A4R43_32055 8040f6c5a4f825e29c72b1a4ff444aea 204 Gene3D G3DSA:2.40.128.20 10 204 4.8E-75 T 14-10-2018 IPR012674 Calycin A4R43_35005 d4161b1786eb37da1511626e075870f7 253 SUPERFAMILY SSF54593 14 126 1.88E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_35005 d4161b1786eb37da1511626e075870f7 253 Gene3D G3DSA:3.10.180.10 9 124 5.0E-31 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_35005 d4161b1786eb37da1511626e075870f7 253 Gene3D G3DSA:3.10.180.10 130 252 4.9E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_35005 d4161b1786eb37da1511626e075870f7 253 SUPERFAMILY SSF54593 137 249 6.36E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_14890 a2ea3185882b8262d2f0314f3ff3c8ad 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 318 2.0E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_18570 992fe0e57d5bdd1648cd80fe68223217 104 SUPERFAMILY SSF49472 1 104 3.01E-34 T 14-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4R43_18570 992fe0e57d5bdd1648cd80fe68223217 104 Gene3D G3DSA:2.60.40.180 1 104 5.8E-37 T 14-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4R43_18570 992fe0e57d5bdd1648cd80fe68223217 104 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 104 2.1E-32 T 14-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4R43_18570 992fe0e57d5bdd1648cd80fe68223217 104 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 14-10-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4R43_18570 992fe0e57d5bdd1648cd80fe68223217 104 Pfam PF00576 HIUase/Transthyretin family 4 103 1.2E-31 T 14-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4R43_13820 4df3688364f1c6cc09fa49e367eed2cc 230 Pfam PF06778 Chlorite dismutase 34 220 2.9E-74 T 14-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase A4R43_13820 4df3688364f1c6cc09fa49e367eed2cc 230 SUPERFAMILY SSF54909 4 229 3.49E-79 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_13820 4df3688364f1c6cc09fa49e367eed2cc 230 Gene3D G3DSA:3.30.70.1100 126 229 6.6E-37 T 14-10-2018 A4R43_15635 57d5b2b1edf4a10dba057bae9ab299ef 196 Gene3D G3DSA:3.40.30.10 7 196 3.3E-64 T 14-10-2018 A4R43_15635 57d5b2b1edf4a10dba057bae9ab299ef 196 SUPERFAMILY SSF52833 8 156 4.92E-14 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_07680 27c5b040160e1f5968c558ad5b3e11d4 294 SUPERFAMILY SSF48317 28 210 3.11E-16 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4R43_07680 27c5b040160e1f5968c558ad5b3e11d4 294 Gene3D G3DSA:1.20.144.10 120 220 1.3E-10 T 14-10-2018 A4R43_07680 27c5b040160e1f5968c558ad5b3e11d4 294 Pfam PF01569 PAP2 superfamily 99 209 1.8E-13 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4R43_30430 7041b0399a5c1d92416c945842661337 201 Gene3D G3DSA:1.10.3300.10 30 199 5.2E-28 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_30430 7041b0399a5c1d92416c945842661337 201 Pfam PF11706 CGNR zinc finger 155 198 6.0E-22 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_30430 7041b0399a5c1d92416c945842661337 201 Pfam PF07336 Putative stress-induced transcription regulator 23 150 1.5E-14 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator A4R43_30430 7041b0399a5c1d92416c945842661337 201 SUPERFAMILY SSF160904 16 197 1.96E-40 T 14-10-2018 A4R43_30410 9198d2e9be001b434b82566aa333e3b4 171 Pfam PF05258 Protein of unknown function (DUF721) 59 146 3.6E-23 T 14-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 A4R43_12845 6ef93811c2a7bb5b8a7d11984d4b9cac 271 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 59 255 2.0E-18 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_12845 6ef93811c2a7bb5b8a7d11984d4b9cac 271 SUPERFAMILY SSF52266 55 267 4.89E-34 T 14-10-2018 A4R43_30385 a41e707f1dfb7fe27075b7a4315a7947 166 Pfam PF01814 Hemerythrin HHE cation binding domain 5 117 5.8E-11 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 A4R43_30385 a41e707f1dfb7fe27075b7a4315a7947 166 Gene3D G3DSA:1.20.120.520 1 140 3.2E-10 T 14-10-2018 A4R43_16525 72bf5370347bda4667d6f48990c538bf 249 Pfam PF07103 Protein of unknown function (DUF1365) 6 229 3.2E-52 T 14-10-2018 IPR010775 Protein of unknown function DUF1365 A4R43_01045 1a82e1fa607849e97d79105626c1a1c4 286 Pfam PF10065 Uncharacterized conserved protein (DUF2303) 49 277 1.5E-60 T 14-10-2018 IPR019276 Protein of unkown function DUF2303 A4R43_05555 37937465ce2c54f73c384009d92424fd 274 Pfam PF05139 Erythromycin esterase 50 118 5.5E-13 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 A4R43_05555 37937465ce2c54f73c384009d92424fd 274 Pfam PF05139 Erythromycin esterase 135 265 4.4E-12 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 A4R43_05555 37937465ce2c54f73c384009d92424fd 274 Gene3D G3DSA:3.30.1870.10 52 119 8.0E-23 T 14-10-2018 A4R43_05555 37937465ce2c54f73c384009d92424fd 274 Gene3D G3DSA:1.20.1440.30 136 154 3.1E-11 T 14-10-2018 A4R43_05555 37937465ce2c54f73c384009d92424fd 274 SUPERFAMILY SSF159501 10 272 2.44E-42 T 14-10-2018 A4R43_05555 37937465ce2c54f73c384009d92424fd 274 Gene3D G3DSA:3.40.1660.10 9 51 8.0E-23 T 14-10-2018 A4R43_05555 37937465ce2c54f73c384009d92424fd 274 Gene3D G3DSA:3.40.1660.10 155 267 3.1E-11 T 14-10-2018 A4R43_20735 d298f55b6bdd067718ec616e21a063ea 226 Gene3D G3DSA:3.40.50.10310 2 225 7.4E-58 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_20735 d298f55b6bdd067718ec616e21a063ea 226 Pfam PF02633 Creatinine amidohydrolase 10 218 8.6E-56 T 14-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_20735 d298f55b6bdd067718ec616e21a063ea 226 SUPERFAMILY SSF102215 10 224 1.44E-54 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_12425 e0af19812aafe52190cbaa1b1c127956 140 SUPERFAMILY SSF55729 14 119 5.58E-10 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_12425 e0af19812aafe52190cbaa1b1c127956 140 Gene3D G3DSA:3.40.630.30 9 124 1.2E-13 T 14-10-2018 A4R43_40775 708ae8d0dc5a969eff74b98b2b2298f8 444 Gene3D G3DSA:3.50.50.60 3 439 5.5E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_40775 708ae8d0dc5a969eff74b98b2b2298f8 444 SUPERFAMILY SSF54373 284 381 1.39E-5 T 14-10-2018 A4R43_40775 708ae8d0dc5a969eff74b98b2b2298f8 444 Pfam PF01593 Flavin containing amine oxidoreductase 14 430 8.2E-37 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4R43_40775 708ae8d0dc5a969eff74b98b2b2298f8 444 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 5.0E-5 T 14-10-2018 A4R43_40775 708ae8d0dc5a969eff74b98b2b2298f8 444 PRINTS PR00419 Adrenodoxin reductase family signature 29 42 5.0E-5 T 14-10-2018 A4R43_40775 708ae8d0dc5a969eff74b98b2b2298f8 444 SUPERFAMILY SSF51905 4 433 8.1E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37530 75d6f90ec470ef754710dc70bdd7adb6 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 3.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_37530 75d6f90ec470ef754710dc70bdd7adb6 204 Gene3D G3DSA:1.10.357.10 6 192 2.3E-60 T 14-10-2018 A4R43_37530 75d6f90ec470ef754710dc70bdd7adb6 204 SUPERFAMILY SSF46689 1 64 2.29E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_00470 279c7b873809f87a48946961bc54dae2 305 SUPERFAMILY SSF103481 200 301 5.36E-16 T 14-10-2018 A4R43_00470 279c7b873809f87a48946961bc54dae2 305 SUPERFAMILY SSF103481 54 159 3.66E-14 T 14-10-2018 A4R43_00470 279c7b873809f87a48946961bc54dae2 305 Pfam PF00892 EamA-like transporter family 22 154 1.6E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_00470 279c7b873809f87a48946961bc54dae2 305 Pfam PF00892 EamA-like transporter family 164 296 9.3E-24 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_26905 d20d013c51f596aa9129ca8211545d04 510 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 47 500 5.8E-73 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4R43_26905 d20d013c51f596aa9129ca8211545d04 510 Pfam PF00939 Sodium:sulfate symporter transmembrane region 37 498 5.9E-65 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4R43_19215 4dfa85596b721277bfb979b021941a66 297 SUPERFAMILY SSF51658 33 291 1.06E-50 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_19215 4dfa85596b721277bfb979b021941a66 297 Pfam PF01261 Xylose isomerase-like TIM barrel 36 241 9.7E-29 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_19215 4dfa85596b721277bfb979b021941a66 297 Gene3D G3DSA:3.20.20.150 3 291 4.8E-68 T 14-10-2018 A4R43_08440 cdc207dd710b86d69514b157543e699e 216 Gene3D G3DSA:3.40.50.150 8 214 1.2E-44 T 14-10-2018 A4R43_08440 cdc207dd710b86d69514b157543e699e 216 Pfam PF13649 Methyltransferase domain 51 141 2.5E-17 T 14-10-2018 A4R43_08440 cdc207dd710b86d69514b157543e699e 216 SUPERFAMILY SSF53335 10 190 2.32E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_14660 3586bf1e4f171814e9c94842353636d8 110 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 53 79 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4R43_14660 3586bf1e4f171814e9c94842353636d8 110 Pfam PF13744 Helix-turn-helix domain 41 98 7.1E-15 T 14-10-2018 IPR039554 HigA2-like, helix-turn-helix domain A4R43_14660 3586bf1e4f171814e9c94842353636d8 110 Gene3D G3DSA:1.10.260.40 18 100 5.6E-20 T 14-10-2018 A4R43_14660 3586bf1e4f171814e9c94842353636d8 110 SUPERFAMILY SSF47413 31 104 1.21E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_14660 3586bf1e4f171814e9c94842353636d8 110 SMART SM00530 42 98 1.4E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_34750 e5abb51ce6626713fd6320204d687dd9 384 Gene3D G3DSA:3.40.50.2300 76 344 4.7E-91 T 14-10-2018 A4R43_34750 e5abb51ce6626713fd6320204d687dd9 384 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 79 351 1.2E-49 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A4R43_34750 e5abb51ce6626713fd6320204d687dd9 384 SUPERFAMILY SSF53822 114 297 1.88E-8 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_34750 e5abb51ce6626713fd6320204d687dd9 384 Gene3D G3DSA:3.40.50.2300 180 376 4.7E-91 T 14-10-2018 A4R43_12965 76ae9c8a35b9bf4b31bb845d0e484ab4 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 307 2.4E-43 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_37065 7092524a27cbabdd3fd945bf03c8ea82 313 Pfam PF08012 Protein of unknown function (DUF1702) 1 305 8.4E-128 T 14-10-2018 IPR012964 Protein of unknown function DUF1702 A4R43_07950 8a60a4047c7639b4424b1ee9f0c9ffe4 211 Pfam PF13649 Methyltransferase domain 50 143 2.0E-26 T 14-10-2018 A4R43_07950 8a60a4047c7639b4424b1ee9f0c9ffe4 211 Gene3D G3DSA:3.40.50.150 2 195 7.5E-43 T 14-10-2018 A4R43_07950 8a60a4047c7639b4424b1ee9f0c9ffe4 211 SUPERFAMILY SSF53335 12 194 3.84E-44 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_05490 67cef58ae287d9155f70bd531f3d5b45 309 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_05490 67cef58ae287d9155f70bd531f3d5b45 309 SUPERFAMILY SSF55120 83 295 2.72E-49 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_05490 67cef58ae287d9155f70bd531f3d5b45 309 Pfam PF00849 RNA pseudouridylate synthase 99 245 1.4E-16 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4R43_05490 67cef58ae287d9155f70bd531f3d5b45 309 Gene3D G3DSA:3.30.2350.10 83 296 4.1E-42 T 14-10-2018 A4R43_24195 f4d2c363d6036bdf558fcdc3b38e7ed2 271 Pfam PF12697 Alpha/beta hydrolase family 25 260 1.3E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_24195 f4d2c363d6036bdf558fcdc3b38e7ed2 271 Gene3D G3DSA:3.40.50.1820 4 270 6.9E-52 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_24195 f4d2c363d6036bdf558fcdc3b38e7ed2 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 4.3E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_24195 f4d2c363d6036bdf558fcdc3b38e7ed2 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 214 228 4.3E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_24195 f4d2c363d6036bdf558fcdc3b38e7ed2 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 4.3E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_24195 f4d2c363d6036bdf558fcdc3b38e7ed2 271 SUPERFAMILY SSF53474 8 269 2.68E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_31535 e0dcf380dc2e37c481dd2feae4183c3d 215 Pfam PF09335 SNARE associated Golgi protein 38 165 1.1E-20 T 14-10-2018 IPR032816 SNARE associated Golgi protein A4R43_05265 529fa885ed05a6de81b2da1285a5ee60 147 SUPERFAMILY SSF53927 3 145 3.49E-35 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_05265 529fa885ed05a6de81b2da1285a5ee60 147 Gene3D G3DSA:3.40.140.10 1 146 1.0E-33 T 14-10-2018 A4R43_05265 529fa885ed05a6de81b2da1285a5ee60 147 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 98 2.9E-17 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A4R43_00340 43cc1a4a020ed39828e11ca917398d85 446 Gene3D G3DSA:1.20.1250.20 10 438 4.5E-76 T 14-10-2018 A4R43_00340 43cc1a4a020ed39828e11ca917398d85 446 SUPERFAMILY SSF103473 16 435 2.49E-76 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_00340 43cc1a4a020ed39828e11ca917398d85 446 Pfam PF07690 Major Facilitator Superfamily 32 401 5.8E-49 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_03595 68fb551950892f0df505d933c9433982 305 Pfam PF00892 EamA-like transporter family 11 135 1.8E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_03595 68fb551950892f0df505d933c9433982 305 Pfam PF00892 EamA-like transporter family 145 278 3.1E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_03595 68fb551950892f0df505d933c9433982 305 SUPERFAMILY SSF103481 181 284 6.67E-15 T 14-10-2018 A4R43_03595 68fb551950892f0df505d933c9433982 305 SUPERFAMILY SSF103481 46 139 3.27E-12 T 14-10-2018 A4R43_01605 c58eefa63acccfffae2cfe2e9e7e7a1e 194 Pfam PF02441 Flavoprotein 12 189 7.2E-28 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4R43_01605 c58eefa63acccfffae2cfe2e9e7e7a1e 194 Gene3D G3DSA:3.40.50.1950 9 194 3.5E-34 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A4R43_01605 c58eefa63acccfffae2cfe2e9e7e7a1e 194 SUPERFAMILY SSF52507 11 181 5.23E-34 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 922 24.002 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 1 916 0.0 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 SUPERFAMILY SSF53383 442 918 5.49E-99 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 SUPERFAMILY SSF53383 1 413 6.3E-93 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 Gene3D G3DSA:3.90.1150.10 731 870 3.4E-40 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 Gene3D G3DSA:3.40.640.10 67 328 5.6E-101 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 Gene3D G3DSA:3.40.640.10 489 707 2.1E-57 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 Pfam PF02347 Glycine cleavage system P-protein 443 699 4.8E-10 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4R43_19160 19837515fa1adfaf78cf6f47716241c3 924 Pfam PF02347 Glycine cleavage system P-protein 1 413 8.6E-167 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4R43_13615 7434f2a9662bb3510c295b60ae266692 472 Gene3D G3DSA:3.90.1150.10 340 463 9.2E-29 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_13615 7434f2a9662bb3510c295b60ae266692 472 Gene3D G3DSA:3.40.640.10 112 338 5.5E-62 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_13615 7434f2a9662bb3510c295b60ae266692 472 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 279 300 - T 14-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A4R43_13615 7434f2a9662bb3510c295b60ae266692 472 Gene3D G3DSA:3.90.1150.170 19 111 4.4E-7 T 14-10-2018 A4R43_13615 7434f2a9662bb3510c295b60ae266692 472 SUPERFAMILY SSF53383 45 462 1.36E-92 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_13615 7434f2a9662bb3510c295b60ae266692 472 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 74 394 5.4E-45 T 14-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A4R43_15665 7a39b32ece6c016284a7804295421e19 775 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 689 748 3.6E-13 T 14-10-2018 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 A4R43_15665 7a39b32ece6c016284a7804295421e19 775 SUPERFAMILY SSF49863 686 774 3.92E-17 T 14-10-2018 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 A4R43_15665 7a39b32ece6c016284a7804295421e19 775 SUPERFAMILY SSF48230 53 375 7.02E-71 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 A4R43_15665 7a39b32ece6c016284a7804295421e19 775 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 415 674 2.1E-71 T 14-10-2018 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 A4R43_15665 7a39b32ece6c016284a7804295421e19 775 SUPERFAMILY SSF74650 414 681 3.72E-72 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A4R43_15665 7a39b32ece6c016284a7804295421e19 775 Gene3D G3DSA:2.60.220.10 684 775 6.2E-18 T 14-10-2018 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 A4R43_15665 7a39b32ece6c016284a7804295421e19 775 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 51 363 2.9E-68 T 14-10-2018 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical A4R43_15665 7a39b32ece6c016284a7804295421e19 775 Gene3D G3DSA:2.70.98.10 413 683 5.9E-84 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4R43_15665 7a39b32ece6c016284a7804295421e19 775 Gene3D G3DSA:1.50.10.100 33 387 5.4E-92 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 A4R43_16405 891f9c36f39deb71ac6219f2131c8b2a 274 PIRSF PIRSF006648 2 273 2.2E-63 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_16405 891f9c36f39deb71ac6219f2131c8b2a 274 Pfam PF01061 ABC-2 type transporter 21 227 2.6E-29 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_13595 c5e998ae0095b9cbf9a3fb944abf0fba 392 Pfam PF09594 Glycosyltransferase family 87 58 289 4.0E-49 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_21315 8024dbcf23ae3630ef1291d9fa58364a 299 Gene3D G3DSA:3.30.30.40 112 149 1.1E-87 T 14-10-2018 A4R43_21315 8024dbcf23ae3630ef1291d9fa58364a 299 Pfam PF01144 Coenzyme A transferase 1 220 1.4E-31 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_21315 8024dbcf23ae3630ef1291d9fa58364a 299 SUPERFAMILY SSF100950 2 286 8.84E-79 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_21315 8024dbcf23ae3630ef1291d9fa58364a 299 Gene3D G3DSA:3.40.1080.10 2 282 1.1E-87 T 14-10-2018 A4R43_21315 8024dbcf23ae3630ef1291d9fa58364a 299 SMART SM00882 1 221 4.3E-44 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_04535 88091f72014e8f4dce8741148b38bd24 163 SUPERFAMILY SSF53098 17 152 4.55E-33 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_04535 88091f72014e8f4dce8741148b38bd24 163 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 20 151 5.3E-27 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4R43_04535 88091f72014e8f4dce8741148b38bd24 163 Gene3D G3DSA:3.30.420.140 16 160 5.7E-41 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 A4R43_04535 88091f72014e8f4dce8741148b38bd24 163 SMART SM00732 17 119 5.5E-22 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A4R43_04535 88091f72014e8f4dce8741148b38bd24 163 Pfam PF03652 Holliday junction resolvase 18 151 1.8E-40 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4R43_04535 88091f72014e8f4dce8741148b38bd24 163 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 17 154 21.902 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4R43_34965 6fbe1af5ebc3688a44235ab51d3c022a 607 SUPERFAMILY SSF51703 3 525 6.28E-153 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_34965 6fbe1af5ebc3688a44235ab51d3c022a 607 Gene3D G3DSA:3.20.20.240 42 477 1.0E-170 T 14-10-2018 A4R43_34965 6fbe1af5ebc3688a44235ab51d3c022a 607 Gene3D G3DSA:3.40.50.280 478 607 1.1E-45 T 14-10-2018 A4R43_34965 6fbe1af5ebc3688a44235ab51d3c022a 607 Pfam PF01642 Methylmalonyl-CoA mutase 44 519 1.4E-136 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4R43_34965 6fbe1af5ebc3688a44235ab51d3c022a 607 TIGRFAM TIGR00642 mmCoA_mut_beta: methylmalonyl-CoA mutase, small subunit 2 606 4.8E-186 T 14-10-2018 IPR004608 Methylmalonyl-CoA mutase, beta chain GO:0004494|GO:0019652|GO:0031419 KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 A4R43_11010 ff48406d9f5accb13ec7ef868cbe7d31 243 Pfam PF00149 Calcineurin-like phosphoesterase 3 185 1.6E-19 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_11010 ff48406d9f5accb13ec7ef868cbe7d31 243 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 243 32.805 T 14-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 A4R43_11010 ff48406d9f5accb13ec7ef868cbe7d31 243 Gene3D G3DSA:3.60.21.10 1 242 1.5E-62 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_11010 ff48406d9f5accb13ec7ef868cbe7d31 243 SUPERFAMILY SSF56300 3 241 9.7E-46 T 14-10-2018 A4R43_21775 9068260b30d63f737f1042a00a2015d6 370 SUPERFAMILY SSF54001 252 368 2.94E-31 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_21775 9068260b30d63f737f1042a00a2015d6 370 Gene3D G3DSA:3.90.1720.10 234 362 3.9E-35 T 14-10-2018 A4R43_21775 9068260b30d63f737f1042a00a2015d6 370 Pfam PF00877 NlpC/P60 family 270 363 4.9E-19 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_06805 7a35a7a4681d098a56f0ba5bfff748f0 238 Pfam PF02517 CAAX protease self-immunity 115 225 7.9E-12 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A4R43_06805 7a35a7a4681d098a56f0ba5bfff748f0 238 PIRSF PIRSF026622 7 237 2.6E-27 T 14-10-2018 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type A4R43_08625 b0615df89a0a94d9cb3886ea50c7adac 165 Gene3D G3DSA:1.10.10.10 4 156 9.3E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08625 b0615df89a0a94d9cb3886ea50c7adac 165 SUPERFAMILY SSF46785 8 121 5.08E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08625 b0615df89a0a94d9cb3886ea50c7adac 165 Pfam PF01638 HxlR-like helix-turn-helix 20 106 3.6E-14 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_28425 2f513a7c9aeffc5c07d21f5f44806354 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 201 2.2E-48 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_28425 2f513a7c9aeffc5c07d21f5f44806354 204 SMART SM00855 2 161 7.5E-22 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_28425 2f513a7c9aeffc5c07d21f5f44806354 204 Gene3D G3DSA:3.40.50.1240 1 201 2.3E-42 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_28425 2f513a7c9aeffc5c07d21f5f44806354 204 SUPERFAMILY SSF53254 2 199 3.68E-47 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_28425 2f513a7c9aeffc5c07d21f5f44806354 204 PIRSF PIRSF000709 2 153 5.7E-5 T 14-10-2018 A4R43_15505 099752452db09cad3fb6f79e27eafa35 271 SUPERFAMILY SSF56601 44 244 7.63E-24 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_15505 099752452db09cad3fb6f79e27eafa35 271 Pfam PF13354 Beta-lactamase enzyme family 105 240 3.0E-7 T 14-10-2018 A4R43_15505 099752452db09cad3fb6f79e27eafa35 271 Gene3D G3DSA:3.40.710.10 40 268 5.7E-30 T 14-10-2018 A4R43_20130 b65396af9923350067cd5c8d16921c6e 293 Pfam PF01553 Acyltransferase 90 202 1.0E-17 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_20130 b65396af9923350067cd5c8d16921c6e 293 SMART SM00563 93 205 3.1E-22 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_20130 b65396af9923350067cd5c8d16921c6e 293 SUPERFAMILY SSF69593 53 220 1.44E-18 T 14-10-2018 A4R43_21905 d058cfbe957b1be13e44703872618239 93 Gene3D G3DSA:1.20.58.1000 4 93 9.1E-35 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily A4R43_21905 d058cfbe957b1be13e44703872618239 93 Pfam PF02583 Metal-sensitive transcriptional repressor 7 88 9.1E-31 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A4R43_01710 e9e119ffb257131c3185b0a985de250a 270 PIRSF PIRSF000105 1 270 9.3E-74 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A4R43_01710 e9e119ffb257131c3185b0a985de250a 270 Gene3D G3DSA:1.10.1040.10 180 270 1.8E-29 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4R43_01710 e9e119ffb257131c3185b0a985de250a 270 SUPERFAMILY SSF51735 1 170 3.38E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_01710 e9e119ffb257131c3185b0a985de250a 270 Gene3D G3DSA:3.40.50.720 1 176 2.7E-53 T 14-10-2018 A4R43_01710 e9e119ffb257131c3185b0a985de250a 270 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 173 269 1.8E-29 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_01710 e9e119ffb257131c3185b0a985de250a 270 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 170 7.6E-53 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A4R43_01710 e9e119ffb257131c3185b0a985de250a 270 SUPERFAMILY SSF48179 173 270 8.5E-29 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4R43_21900 bb0530c8a1c49ecc331c30d4775bf0b8 249 SUPERFAMILY SSF52540 6 224 1.05E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21900 bb0530c8a1c49ecc331c30d4775bf0b8 249 Pfam PF00005 ABC transporter 25 171 7.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_21900 bb0530c8a1c49ecc331c30d4775bf0b8 249 SMART SM00382 34 220 7.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_21900 bb0530c8a1c49ecc331c30d4775bf0b8 249 Gene3D G3DSA:3.40.50.300 3 244 1.5E-67 T 14-10-2018 A4R43_21900 bb0530c8a1c49ecc331c30d4775bf0b8 249 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_33570 db967ae27392338115aac0eb756a91a0 334 SUPERFAMILY SSF53807 35 327 7.85E-23 T 14-10-2018 A4R43_33570 db967ae27392338115aac0eb756a91a0 334 Gene3D G3DSA:3.40.50.1980 33 172 4.8E-38 T 14-10-2018 A4R43_33570 db967ae27392338115aac0eb756a91a0 334 Gene3D G3DSA:3.40.50.1980 179 329 9.7E-41 T 14-10-2018 A4R43_33570 db967ae27392338115aac0eb756a91a0 334 Pfam PF01497 Periplasmic binding protein 58 307 1.0E-29 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_40485 a7d6444e9abe02d86836467588ac9087 125 Gene3D G3DSA:3.30.750.24 6 118 1.5E-23 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_40485 a7d6444e9abe02d86836467588ac9087 125 Pfam PF13466 STAS domain 22 100 1.1E-10 T 14-10-2018 IPR002645 STAS domain A4R43_40485 a7d6444e9abe02d86836467588ac9087 125 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 12 112 1.3E-18 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_40485 a7d6444e9abe02d86836467588ac9087 125 SUPERFAMILY SSF52091 12 117 8.63E-18 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_37245 c4763cb70cb118b7b805941c0362e6ad 616 SUPERFAMILY SSF52402 235 591 1.49E-66 T 14-10-2018 A4R43_37245 c4763cb70cb118b7b805941c0362e6ad 616 Gene3D G3DSA:3.60.20.10 3 179 1.7E-64 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_37245 c4763cb70cb118b7b805941c0362e6ad 616 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 540 1.9E-143 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_37245 c4763cb70cb118b7b805941c0362e6ad 616 SUPERFAMILY SSF56235 1 223 4.2E-65 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4R43_37245 c4763cb70cb118b7b805941c0362e6ad 616 Pfam PF13537 Glutamine amidotransferase domain 49 166 1.3E-46 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4R43_37245 c4763cb70cb118b7b805941c0362e6ad 616 Pfam PF00733 Asparagine synthase 242 581 5.6E-76 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4R43_37245 c4763cb70cb118b7b805941c0362e6ad 616 PIRSF PIRSF001589 1 600 7.1E-164 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 SUPERFAMILY SSF46785 19 90 1.51E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 SUPERFAMILY SSF64288 72 251 2.36E-55 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 83 2.0E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 SMART SM00866 104 244 1.3E-46 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 SMART SM00345 27 84 5.0E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 Gene3D G3DSA:3.40.1410.10 87 252 2.8E-61 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 1.1E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 1.1E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 Pfam PF07702 UTRA domain 105 244 4.3E-46 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4R43_26205 53595b5576713a89aeab061b5cbef45c 252 Gene3D G3DSA:1.10.10.10 10 86 5.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_23220 7425dd8fd500707f672f79bdc5647b77 578 Pfam PF10646 Sporulation and spore germination 176 285 8.3E-8 T 14-10-2018 IPR019606 GerMN domain A4R43_23220 7425dd8fd500707f672f79bdc5647b77 578 SUPERFAMILY SSF50969 336 545 1.41E-6 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A4R43_23220 7425dd8fd500707f672f79bdc5647b77 578 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 327 577 1.6E-48 T 14-10-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal A4R43_06310 d488270466d4a487b76c29e504ed231a 251 Pfam PF13462 Thioredoxin 74 229 7.2E-27 T 14-10-2018 IPR012336 Thioredoxin-like fold A4R43_06310 d488270466d4a487b76c29e504ed231a 251 SUPERFAMILY SSF52833 64 229 1.63E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_06310 d488270466d4a487b76c29e504ed231a 251 Gene3D G3DSA:3.40.30.10 53 249 2.1E-43 T 14-10-2018 A4R43_05880 fa50ec1a1472fc51c01a83f54c55e07f 351 SUPERFAMILY SSF140453 5 99 8.11E-5 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_05110 06727be054344f7ce095271da8016d8c 524 SUPERFAMILY SSF109604 31 274 1.71E-47 T 14-10-2018 A4R43_05110 06727be054344f7ce095271da8016d8c 524 Pfam PF01966 HD domain 66 148 7.7E-12 T 14-10-2018 IPR006674 HD domain A4R43_05110 06727be054344f7ce095271da8016d8c 524 SMART SM00471 62 264 7.2E-12 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_05110 06727be054344f7ce095271da8016d8c 524 Gene3D G3DSA:1.10.3210.10 3 317 1.7E-64 T 14-10-2018 A4R43_05110 06727be054344f7ce095271da8016d8c 524 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 30 511 3.2E-62 T 14-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 A4R43_36965 7c65ade587ff0bd330151e1bdc520841 404 Pfam PF07690 Major Facilitator Superfamily 226 399 7.3E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_36965 7c65ade587ff0bd330151e1bdc520841 404 SUPERFAMILY SSF103473 15 394 2.75E-29 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_36965 7c65ade587ff0bd330151e1bdc520841 404 Gene3D G3DSA:1.20.1250.20 12 391 4.2E-22 T 14-10-2018 A4R43_09900 c8e0f86b033cc5decf71d69dd5469cc9 332 Pfam PF01032 FecCD transport family 21 326 3.4E-78 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_09900 c8e0f86b033cc5decf71d69dd5469cc9 332 SUPERFAMILY SSF81345 12 326 1.28E-67 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_09900 c8e0f86b033cc5decf71d69dd5469cc9 332 Gene3D G3DSA:1.10.3470.10 10 329 6.4E-81 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_11610 f08485ac41c75dcb6ef1538e7e3bcff8 168 Pfam PF00582 Universal stress protein family 15 166 3.2E-20 T 14-10-2018 IPR006016 UspA A4R43_11610 f08485ac41c75dcb6ef1538e7e3bcff8 168 PRINTS PR01438 Universal stress protein signature 126 138 7.4E-15 T 14-10-2018 IPR006015 Universal stress protein A A4R43_11610 f08485ac41c75dcb6ef1538e7e3bcff8 168 PRINTS PR01438 Universal stress protein signature 144 166 7.4E-15 T 14-10-2018 IPR006015 Universal stress protein A A4R43_11610 f08485ac41c75dcb6ef1538e7e3bcff8 168 PRINTS PR01438 Universal stress protein signature 13 31 7.4E-15 T 14-10-2018 IPR006015 Universal stress protein A A4R43_11610 f08485ac41c75dcb6ef1538e7e3bcff8 168 Gene3D G3DSA:3.40.50.620 3 166 2.9E-26 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_11610 f08485ac41c75dcb6ef1538e7e3bcff8 168 SUPERFAMILY SSF52402 15 167 1.0E-25 T 14-10-2018 A4R43_32655 ed7bb3636e1162364c3c2b7140782fc5 157 Pfam PF11706 CGNR zinc finger 111 154 1.3E-18 T 14-10-2018 IPR021005 Zinc finger, CGNR A4R43_32655 ed7bb3636e1162364c3c2b7140782fc5 157 Pfam PF07336 Putative stress-induced transcription regulator 11 102 1.0E-6 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator A4R43_32655 ed7bb3636e1162364c3c2b7140782fc5 157 SUPERFAMILY SSF160904 6 153 8.89E-33 T 14-10-2018 A4R43_32655 ed7bb3636e1162364c3c2b7140782fc5 157 Gene3D G3DSA:1.10.3300.10 3 155 1.5E-23 T 14-10-2018 IPR023286 ABATE domain superfamily A4R43_22475 9e58f49b11408166611dea8aa9afb777 276 Pfam PF11303 Protein of unknown function (DUF3105) 82 208 1.5E-43 T 14-10-2018 IPR021454 Protein of unknown function DUF3105 A4R43_35805 fb6c6483fc85bc7d53ddc9932c53978a 288 Pfam PF12705 PD-(D/E)XK nuclease superfamily 16 264 6.9E-35 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A4R43_27250 5709b1a83f44e0001326bdaaab38ce74 718 Gene3D G3DSA:1.10.3810.10 59 267 8.8E-69 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_27250 5709b1a83f44e0001326bdaaab38ce74 718 Gene3D G3DSA:3.40.710.10 290 714 2.1E-62 T 14-10-2018 A4R43_27250 5709b1a83f44e0001326bdaaab38ce74 718 SUPERFAMILY SSF53955 55 273 1.01E-67 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_27250 5709b1a83f44e0001326bdaaab38ce74 718 SUPERFAMILY SSF56601 234 709 1.49E-68 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_27250 5709b1a83f44e0001326bdaaab38ce74 718 Pfam PF00905 Penicillin binding protein transpeptidase domain 361 647 8.9E-16 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4R43_27250 5709b1a83f44e0001326bdaaab38ce74 718 Pfam PF00912 Transglycosylase 66 252 3.9E-61 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_37470 b29a4310bcc36680cb9ccbe475dae103 300 Gene3D G3DSA:3.40.50.620 9 210 1.2E-59 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_37470 b29a4310bcc36680cb9ccbe475dae103 300 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 11 300 5.5E-138 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4R43_37470 b29a4310bcc36680cb9ccbe475dae103 300 PIRSF PIRSF002936 2 300 3.2E-138 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4R43_37470 b29a4310bcc36680cb9ccbe475dae103 300 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 32 253 1.1E-48 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A4R43_37470 b29a4310bcc36680cb9ccbe475dae103 300 SUPERFAMILY SSF52402 7 208 6.52E-68 T 14-10-2018 A4R43_03635 1ac12c797983fd5e3c04c57e924a849a 238 Pfam PF01925 Sulfite exporter TauE/SafE 11 230 2.4E-21 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A4R43_08690 224cf5b38e1fb8e04fc983f83af9d548 381 SUPERFAMILY SSF88946 3 85 1.26E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08690 224cf5b38e1fb8e04fc983f83af9d548 381 Pfam PF04542 Sigma-70 region 2 5 70 2.0E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_08690 224cf5b38e1fb8e04fc983f83af9d548 381 SUPERFAMILY SSF88659 92 149 2.18E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_08690 224cf5b38e1fb8e04fc983f83af9d548 381 Gene3D G3DSA:1.10.1740.10 3 69 8.2E-6 T 14-10-2018 A4R43_08690 224cf5b38e1fb8e04fc983f83af9d548 381 Gene3D G3DSA:1.10.10.10 90 152 6.9E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08690 224cf5b38e1fb8e04fc983f83af9d548 381 Pfam PF08281 Sigma-70, region 4 98 148 7.2E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_21405 00d361f581eb2cdb3482950597282c36 142 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 12 113 4.0E-13 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A4R43_21405 00d361f581eb2cdb3482950597282c36 142 Gene3D G3DSA:3.30.1380.10 3 118 1.1E-17 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_21405 00d361f581eb2cdb3482950597282c36 142 SUPERFAMILY SSF55166 8 117 1.57E-21 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_07025 b0ec88e224e380c765bc643503c34eb3 299 Gene3D G3DSA:1.10.3720.10 52 294 5.1E-67 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_07025 b0ec88e224e380c765bc643503c34eb3 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 284 6.6E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_07025 b0ec88e224e380c765bc643503c34eb3 299 SUPERFAMILY SSF161098 56 283 4.32E-59 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 Gene3D G3DSA:2.40.10.480 389 479 1.7E-10 T 14-10-2018 A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 Pfam PF13360 PQQ-like domain 84 232 1.6E-16 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 Pfam PF13360 PQQ-like domain 281 477 6.2E-16 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 Gene3D G3DSA:2.140.10.10 31 388 7.8E-76 T 14-10-2018 A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 SUPERFAMILY SSF50998 38 480 1.83E-84 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 SMART SM00564 136 168 0.03 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 SMART SM00564 256 298 0.49 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 SMART SM00564 447 479 1.1E-4 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 SMART SM00564 180 227 0.26 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 SMART SM00564 387 422 0.0015 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 SMART SM00564 337 371 190.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4R43_37700 cc75306e804d8094f1324e46964b65a8 533 SMART SM00564 88 119 8.9E-5 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4R43_22635 2f0591e2c27e206a7f29696741873c85 551 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 89 238 4.4E-7 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4R43_41835 1bcbbe905e8ec601ca691e45edbd969a 169 Pfam PF04978 Protein of unknown function (DUF664) 17 165 1.4E-44 T 14-10-2018 IPR007061 Protein of unknown function DUF664 A4R43_41835 1bcbbe905e8ec601ca691e45edbd969a 169 SUPERFAMILY SSF109854 4 164 7.48E-41 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_41835 1bcbbe905e8ec601ca691e45edbd969a 169 Gene3D G3DSA:1.20.120.450 7 168 1.2E-32 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_18560 98dd6360ec7c628beca1191e45ec6e22 131 Pfam PF13309 HTH domain 58 119 1.0E-19 T 14-10-2018 IPR039445 Transcriptional regulator DauR-like, HTH domain A4R43_24375 ccb9d21ad5c6d02ac15f92af25e86594 127 SUPERFAMILY SSF54593 7 126 3.49E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_24375 ccb9d21ad5c6d02ac15f92af25e86594 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 123 2.6E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_24375 ccb9d21ad5c6d02ac15f92af25e86594 127 Gene3D G3DSA:3.10.180.10 1 126 8.1E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_01680 5c4fa892cb4bc70928ddd308204951d2 160 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 156 7.5E-10 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_01680 5c4fa892cb4bc70928ddd308204951d2 160 Gene3D G3DSA:3.30.530.20 6 159 3.1E-39 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_01680 5c4fa892cb4bc70928ddd308204951d2 160 SUPERFAMILY SSF55961 8 157 2.24E-35 T 14-10-2018 A4R43_17635 1b061862a8afd1e04ed6b635f5cf9283 375 Gene3D G3DSA:3.40.50.2000 1 356 4.5E-121 T 14-10-2018 A4R43_17635 1b061862a8afd1e04ed6b635f5cf9283 375 Gene3D G3DSA:3.40.50.2000 162 355 4.5E-121 T 14-10-2018 A4R43_17635 1b061862a8afd1e04ed6b635f5cf9283 375 Pfam PF13439 Glycosyltransferase Family 4 9 164 1.4E-10 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_17635 1b061862a8afd1e04ed6b635f5cf9283 375 Pfam PF00534 Glycosyl transferases group 1 173 348 2.3E-38 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_17635 1b061862a8afd1e04ed6b635f5cf9283 375 SUPERFAMILY SSF53756 1 366 2.65E-74 T 14-10-2018 A4R43_23910 01560f4e43fd4b137f7b5f79d616890c 175 Pfam PF04417 Protein of unknown function (DUF501) 34 155 1.4E-36 T 14-10-2018 IPR007511 Protein of unknown function DUF501 A4R43_24725 6b71c2a64a8ce2970183743fd876f860 165 SUPERFAMILY SSF52402 6 130 6.28E-5 T 14-10-2018 A4R43_36880 8ccd75e25f6e3bb3523f3594014ee94d 209 SUPERFAMILY SSF53254 2 202 3.68E-53 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_36880 8ccd75e25f6e3bb3523f3594014ee94d 209 SMART SM00855 4 159 5.4E-18 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_36880 8ccd75e25f6e3bb3523f3594014ee94d 209 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 199 9.1E-49 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_36880 8ccd75e25f6e3bb3523f3594014ee94d 209 Gene3D G3DSA:3.40.50.1240 2 197 3.0E-49 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_36880 8ccd75e25f6e3bb3523f3594014ee94d 209 PIRSF PIRSF000709 3 173 5.3E-8 T 14-10-2018 A4R43_18085 eca73be6f5452a2e29a063805f7041c9 410 SUPERFAMILY SSF53901 4 253 1.98E-64 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_18085 eca73be6f5452a2e29a063805f7041c9 410 PIRSF PIRSF000447 1 410 2.6E-139 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4R43_18085 eca73be6f5452a2e29a063805f7041c9 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 9.7E-55 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4R43_18085 eca73be6f5452a2e29a063805f7041c9 410 SMART SM00825 Beta-ketoacyl synthase 6 401 6.6E-12 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4R43_18085 eca73be6f5452a2e29a063805f7041c9 410 Gene3D G3DSA:3.40.47.10 261 409 1.7E-44 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_18085 eca73be6f5452a2e29a063805f7041c9 410 SUPERFAMILY SSF53901 215 408 1.83E-63 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_18085 eca73be6f5452a2e29a063805f7041c9 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 367 1.6E-33 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4R43_18085 eca73be6f5452a2e29a063805f7041c9 410 Gene3D G3DSA:3.40.47.10 1 257 8.4E-75 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_41140 ec6c59eb1d598f3a36febe6ec9de3a87 159 SUPERFAMILY SSF47413 21 62 1.75E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_15690 efe983304cbe1814c571576b84565bc6 274 Gene3D G3DSA:3.40.50.720 3 236 2.6E-55 T 14-10-2018 A4R43_15690 efe983304cbe1814c571576b84565bc6 274 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 170 3.6E-18 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_15690 efe983304cbe1814c571576b84565bc6 274 SUPERFAMILY SSF51735 1 243 3.04E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_16480 712a098158910b41e68db13ae1f7f7de 220 SUPERFAMILY SSF57884 187 209 4.18E-5 T 14-10-2018 IPR035451 Ada-like domain superfamily A4R43_18655 5028debcb51038d845471d438cb4759d 525 Gene3D G3DSA:1.20.1730.10 23 521 1.2E-86 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_18655 5028debcb51038d845471d438cb4759d 525 Pfam PF00474 Sodium:solute symporter family 33 443 4.3E-23 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_05980 be98dff09dd4daec96be3ffb0ac72c39 116 Pfam PF13564 DoxX-like family 7 108 7.0E-25 T 14-10-2018 IPR032808 DoxX family A4R43_03900 16669545bdea8a9ca2d1135a6d2b1cf7 809 Pfam PF02687 FtsX-like permease family 712 802 1.1E-12 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_03900 16669545bdea8a9ca2d1135a6d2b1cf7 809 Pfam PF02687 FtsX-like permease family 269 360 1.2E-12 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_03900 16669545bdea8a9ca2d1135a6d2b1cf7 809 Pfam PF12704 MacB-like periplasmic core domain 10 210 8.3E-10 T 14-10-2018 IPR025857 MacB-like periplasmic core domain A4R43_03900 16669545bdea8a9ca2d1135a6d2b1cf7 809 Pfam PF12704 MacB-like periplasmic core domain 457 653 9.0E-10 T 14-10-2018 IPR025857 MacB-like periplasmic core domain A4R43_25025 4656a146436a7b7483754ff50d6f33bc 364 Gene3D G3DSA:3.90.420.10 212 364 3.6E-27 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A4R43_25025 4656a146436a7b7483754ff50d6f33bc 364 Pfam PF00174 Oxidoreductase molybdopterin binding domain 233 363 6.0E-22 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4R43_25025 4656a146436a7b7483754ff50d6f33bc 364 SUPERFAMILY SSF56524 232 363 5.76E-32 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A4R43_25025 4656a146436a7b7483754ff50d6f33bc 364 PRINTS PR00407 Eukaryotic molybdopterin domain signature 318 334 1.9E-8 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 A4R43_25025 4656a146436a7b7483754ff50d6f33bc 364 PRINTS PR00407 Eukaryotic molybdopterin domain signature 270 285 1.9E-8 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 A4R43_25025 4656a146436a7b7483754ff50d6f33bc 364 PRINTS PR00407 Eukaryotic molybdopterin domain signature 335 348 1.9E-8 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 A4R43_25025 4656a146436a7b7483754ff50d6f33bc 364 PRINTS PR00407 Eukaryotic molybdopterin domain signature 351 364 1.9E-8 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 A4R43_25025 4656a146436a7b7483754ff50d6f33bc 364 SUPERFAMILY SSF81342 22 151 1.88E-6 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4R43_07350 2a068bf829ea8b7e29983fc437fd75ba 167 SUPERFAMILY SSF55729 3 145 2.74E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_07350 2a068bf829ea8b7e29983fc437fd75ba 167 Gene3D G3DSA:3.40.630.30 4 153 6.0E-26 T 14-10-2018 A4R43_07350 2a068bf829ea8b7e29983fc437fd75ba 167 Pfam PF13673 Acetyltransferase (GNAT) domain 38 144 8.1E-12 T 14-10-2018 IPR000182 GNAT domain A4R43_01355 9c1de24ee105722b1b56c64e8c3a3d32 406 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 131 348 3.8E-20 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 A4R43_32360 82560ba013d0505cb7bce77af036cd0e 209 Pfam PF09335 SNARE associated Golgi protein 39 163 4.6E-16 T 14-10-2018 IPR032816 SNARE associated Golgi protein A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 Pfam PF00232 Glycosyl hydrolase family 1 266 383 4.6E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 Pfam PF00232 Glycosyl hydrolase family 1 2 223 4.6E-37 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 PRINTS PR00131 Glycosyl hydrolase family 1 signature 354 366 2.4E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 PRINTS PR00131 Glycosyl hydrolase family 1 signature 242 256 2.4E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 PRINTS PR00131 Glycosyl hydrolase family 1 signature 331 348 2.4E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 PRINTS PR00131 Glycosyl hydrolase family 1 signature 298 306 2.4E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 PRINTS PR00131 Glycosyl hydrolase family 1 signature 310 321 2.4E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 SUPERFAMILY SSF51445 2 384 1.31E-102 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_24285 baf7d8c02934987704eaf6d3211f51b9 385 Gene3D G3DSA:3.20.20.80 1 385 8.2E-103 T 14-10-2018 A4R43_07390 559ed60c20a96158012625cd1c473861 387 SUPERFAMILY SSF63433 3 94 2.62E-23 T 14-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4R43_07390 559ed60c20a96158012625cd1c473861 387 SUPERFAMILY SSF56529 96 385 3.66E-89 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_07390 559ed60c20a96158012625cd1c473861 387 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 2 386 4.2E-127 T 14-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4R43_07390 559ed60c20a96158012625cd1c473861 387 Gene3D G3DSA:2.30.30.230 1 91 4.0E-19 T 14-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4R43_07390 559ed60c20a96158012625cd1c473861 387 Gene3D G3DSA:3.90.850.10 92 387 3.5E-106 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_07390 559ed60c20a96158012625cd1c473861 387 Pfam PF09298 Fumarylacetoacetase N-terminal 12 94 3.3E-18 T 14-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4R43_07390 559ed60c20a96158012625cd1c473861 387 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 100 383 2.8E-54 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_26105 5138e4dbc5a65c63e224378456d021c7 319 Pfam PF01066 CDP-alcohol phosphatidyltransferase 12 75 1.5E-13 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4R43_26105 5138e4dbc5a65c63e224378456d021c7 319 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 53 75 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4R43_26105 5138e4dbc5a65c63e224378456d021c7 319 Pfam PF08009 CDP-alcohol phosphatidyltransferase 2 196 230 1.4E-5 T 14-10-2018 IPR012616 CDP-alcohol phosphatidyltransferase, C-terminal A4R43_26105 5138e4dbc5a65c63e224378456d021c7 319 Gene3D G3DSA:1.20.120.1760 3 185 3.3E-15 T 14-10-2018 A4R43_26105 5138e4dbc5a65c63e224378456d021c7 319 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 17 181 5.6E-34 T 14-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 A4R43_32760 ada86a5589adf8dbcab3c032998b3a15 289 Pfam PF14257 Domain of unknown function (DUF4349) 8 271 2.5E-65 T 14-10-2018 IPR025645 Domain of unknown function DUF4349 A4R43_04060 c1555c3cd0e74e2a8326fa7687f7b2d8 311 SUPERFAMILY SSF161098 91 287 1.02E-12 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_04060 c1555c3cd0e74e2a8326fa7687f7b2d8 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 304 2.2E-33 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_04060 c1555c3cd0e74e2a8326fa7687f7b2d8 311 Gene3D G3DSA:1.10.3720.10 85 297 1.0E-15 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_04900 0cb5e5a37c29bef7c10341bd0640324f 197 SUPERFAMILY SSF55729 6 194 1.75E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_04900 0cb5e5a37c29bef7c10341bd0640324f 197 Pfam PF13673 Acetyltransferase (GNAT) domain 121 192 4.4E-9 T 14-10-2018 IPR000182 GNAT domain A4R43_04900 0cb5e5a37c29bef7c10341bd0640324f 197 Gene3D G3DSA:3.40.630.30 3 197 1.1E-39 T 14-10-2018 A4R43_23195 beef952101ca4d2cec22db850e96ab67 128 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 23 106 6.1E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_23195 beef952101ca4d2cec22db850e96ab67 128 Gene3D G3DSA:3.40.50.1000 2 127 2.1E-30 T 14-10-2018 IPR023214 HAD superfamily A4R43_23195 beef952101ca4d2cec22db850e96ab67 128 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 35 111 2.9E-14 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_23195 beef952101ca4d2cec22db850e96ab67 128 SUPERFAMILY SSF56784 4 122 8.27E-25 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_23195 beef952101ca4d2cec22db850e96ab67 128 Pfam PF00702 haloacid dehalogenase-like hydrolase 23 106 8.0E-10 T 14-10-2018 A4R43_03215 4d31d2de1a66497dcf9d484b9f101ee9 444 Gene3D G3DSA:3.90.1150.10 34 436 1.0E-135 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_03215 4d31d2de1a66497dcf9d484b9f101ee9 444 SUPERFAMILY SSF53383 32 438 4.61E-82 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_03215 4d31d2de1a66497dcf9d484b9f101ee9 444 PIRSF PIRSF000521 1 442 1.1E-161 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_03215 4d31d2de1a66497dcf9d484b9f101ee9 444 Pfam PF00202 Aminotransferase class-III 28 437 2.3E-76 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4R43_03215 4d31d2de1a66497dcf9d484b9f101ee9 444 TIGRFAM TIGR03251 LAT_fam: L-lysine 6-transaminase 11 437 5.7E-197 T 14-10-2018 IPR017657 L-lysine 6-transaminase GO:0017000|GO:0030170|GO:0045484 MetaCyc: PWY-5298 A4R43_03215 4d31d2de1a66497dcf9d484b9f101ee9 444 Gene3D G3DSA:3.40.640.10 65 347 1.0E-135 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_01310 5a1563cea71fb5416971d1287eae0bf2 117 SUPERFAMILY SSF54593 8 117 7.14E-8 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_01310 5a1563cea71fb5416971d1287eae0bf2 117 Gene3D G3DSA:3.10.180.10 2 117 5.0E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 Gene3D G3DSA:3.10.150.10 1 116 3.0E-14 T 14-10-2018 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 SUPERFAMILY SSF55979 239 349 1.26E-13 T 14-10-2018 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 SUPERFAMILY SSF55979 1 106 5.76E-11 T 14-10-2018 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 SUPERFAMILY SSF55979 120 227 1.26E-8 T 14-10-2018 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 SMART SM00480 17 346 2.0E-9 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 Gene3D G3DSA:3.10.150.10 237 352 9.5E-17 T 14-10-2018 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 27 108 1.4E-9 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 Pfam PF02767 DNA polymerase III beta subunit, central domain 121 227 5.8E-12 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 Gene3D G3DSA:3.10.150.10 117 229 4.3E-16 T 14-10-2018 A4R43_27180 6f883af96ee82ebe8512853508d43b48 362 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 240 349 2.9E-12 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4R43_11570 6121ac4b42fd63fca8920a7d5e3eeb80 227 Pfam PF01063 Amino-transferase class IV 3 195 8.9E-22 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A4R43_11570 6121ac4b42fd63fca8920a7d5e3eeb80 227 SUPERFAMILY SSF56752 5 198 1.57E-27 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A4R43_11570 6121ac4b42fd63fca8920a7d5e3eeb80 227 Gene3D G3DSA:3.20.10.10 103 221 5.3E-15 T 14-10-2018 A4R43_17195 e170ada06718ad828bcb75bb32396a85 341 SUPERFAMILY SSF53686 28 295 1.83E-44 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_17195 e170ada06718ad828bcb75bb32396a85 341 Gene3D G3DSA:3.40.50.1100 135 290 2.4E-43 T 14-10-2018 A4R43_17195 e170ada06718ad828bcb75bb32396a85 341 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 268 6.6E-27 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_17195 e170ada06718ad828bcb75bb32396a85 341 Gene3D G3DSA:3.40.50.1100 29 134 2.4E-43 T 14-10-2018 A4R43_04925 48797d59dd778954a2ba51daf454c1e2 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 254 59.305 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04925 48797d59dd778954a2ba51daf454c1e2 261 Pfam PF00121 Triosephosphate isomerase 6 252 2.9E-89 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04925 48797d59dd778954a2ba51daf454c1e2 261 Gene3D G3DSA:3.20.20.70 1 261 7.5E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_04925 48797d59dd778954a2ba51daf454c1e2 261 SUPERFAMILY SSF51351 2 254 1.57E-90 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04925 48797d59dd778954a2ba51daf454c1e2 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 170 180 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_04925 48797d59dd778954a2ba51daf454c1e2 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 246 9.4E-54 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_30150 2dd8b04c9a532377e9ff64b1bc318aeb 290 Pfam PF02405 Permease MlaE 67 277 7.2E-52 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_27535 a9abbf01d556c22a8fb8cbae03bbb42d 248 SUPERFAMILY SSF81923 98 234 2.85E-25 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_27535 a9abbf01d556c22a8fb8cbae03bbb42d 248 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 110 157 4.0E-9 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_27535 a9abbf01d556c22a8fb8cbae03bbb42d 248 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 187 236 1.4E-12 T 14-10-2018 IPR004176 Clp, N-terminal A4R43_27535 a9abbf01d556c22a8fb8cbae03bbb42d 248 Gene3D G3DSA:1.10.1780.10 95 244 5.6E-37 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4R43_41705 1fd0fa9185ea3978796aebab8e2c4167 187 Gene3D G3DSA:3.40.630.30 3 167 3.7E-43 T 14-10-2018 A4R43_41705 1fd0fa9185ea3978796aebab8e2c4167 187 Pfam PF13302 Acetyltransferase (GNAT) domain 12 154 9.8E-32 T 14-10-2018 IPR000182 GNAT domain A4R43_41705 1fd0fa9185ea3978796aebab8e2c4167 187 SUPERFAMILY SSF55729 6 160 2.71E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_29170 a343c01a2bcbac4feade6b2c779f827e 174 SUPERFAMILY SSF55724 36 173 6.28E-44 T 14-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich A4R43_29170 a343c01a2bcbac4feade6b2c779f827e 174 Gene3D G3DSA:3.40.1000.10 32 174 3.5E-47 T 14-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich A4R43_29170 a343c01a2bcbac4feade6b2c779f827e 174 Pfam PF09449 Domain of unknown function (DUF2020) 42 173 2.7E-37 T 14-10-2018 IPR018567 Domain of unknown function DUF2020 A4R43_10340 05454e5c423a42cc88a14427ce7e4d93 378 Gene3D G3DSA:1.10.10.2840 253 377 2.3E-17 T 14-10-2018 A4R43_10340 05454e5c423a42cc88a14427ce7e4d93 378 Pfam PF13556 PucR C-terminal helix-turn-helix domain 314 363 7.8E-14 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_40085 3df81b1bed60e9af8e5515a2bef150cd 120 Gene3D G3DSA:3.10.180.10 3 119 4.7E-13 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_40085 3df81b1bed60e9af8e5515a2bef150cd 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 6.2E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_40085 3df81b1bed60e9af8e5515a2bef150cd 120 SUPERFAMILY SSF54593 1 118 1.88E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_35220 2dcdbc0616871de38b718cae760c821a 184 Pfam PF03703 Bacterial PH domain 80 155 1.7E-18 T 14-10-2018 IPR005182 Domain of unknown function DUF304 A4R43_28300 63236d2eb1711f986b93a11058c30fb5 400 Pfam PF13579 Glycosyl transferase 4-like domain 15 136 5.0E-17 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_28300 63236d2eb1711f986b93a11058c30fb5 400 Gene3D G3DSA:3.40.50.2000 6 385 5.6E-55 T 14-10-2018 A4R43_28300 63236d2eb1711f986b93a11058c30fb5 400 Pfam PF00534 Glycosyl transferases group 1 205 365 1.1E-18 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_28300 63236d2eb1711f986b93a11058c30fb5 400 SUPERFAMILY SSF53756 2 389 1.07E-54 T 14-10-2018 A4R43_28300 63236d2eb1711f986b93a11058c30fb5 400 Gene3D G3DSA:3.40.50.2000 191 370 5.6E-55 T 14-10-2018 A4R43_36365 10fe051a9b4d6b3f93f53d29d0761c6c 255 Gene3D G3DSA:3.60.15.10 1 255 4.2E-66 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_36365 10fe051a9b4d6b3f93f53d29d0761c6c 255 SMART SM00849 18 205 9.4E-4 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_36365 10fe051a9b4d6b3f93f53d29d0761c6c 255 Pfam PF12706 Beta-lactamase superfamily domain 44 223 1.4E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_36365 10fe051a9b4d6b3f93f53d29d0761c6c 255 SUPERFAMILY SSF56281 2 237 2.17E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_29060 8762a7389de665807203beac4f33d077 350 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 25 348 3.9E-75 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_29060 8762a7389de665807203beac4f33d077 350 Gene3D G3DSA:3.40.640.10 5 243 1.4E-61 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_29060 8762a7389de665807203beac4f33d077 350 SUPERFAMILY SSF53383 46 349 3.74E-70 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_29060 8762a7389de665807203beac4f33d077 350 Gene3D G3DSA:3.90.1150.10 245 350 3.6E-22 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_29060 8762a7389de665807203beac4f33d077 350 PIRSF PIRSF001434 2 350 2.7E-94 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4R43_07295 93ffe7fa2033940f36763fe26aca56a4 475 Pfam PF08386 TAP-like protein 373 475 4.3E-24 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_07295 93ffe7fa2033940f36763fe26aca56a4 475 SUPERFAMILY SSF53474 71 463 1.08E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16300 329c2ef4494fd57f764f8ebe087a20ce 365 SUPERFAMILY SSF50939 97 287 3.34E-5 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_20590 be6ea2856826f26f12e0189cbf320c90 368 Pfam PF16701 Adenylate cyclase regulatory domain 19 132 7.3E-11 T 14-10-2018 IPR032026 Adenylate cyclase regulatory domain A4R43_20590 be6ea2856826f26f12e0189cbf320c90 368 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 170 317 1.9E-13 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4R43_20590 be6ea2856826f26f12e0189cbf320c90 368 SMART SM00044 120 306 0.0038 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4R43_20590 be6ea2856826f26f12e0189cbf320c90 368 Gene3D G3DSA:3.30.70.1230 150 321 4.3E-43 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_20590 be6ea2856826f26f12e0189cbf320c90 368 SUPERFAMILY SSF55073 164 317 5.18E-33 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_06120 d567b8c165bc451d77fc7ab6cc5180ae 142 SMART SM00347 29 128 7.6E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06120 d567b8c165bc451d77fc7ab6cc5180ae 142 Pfam PF12802 MarR family 34 88 2.4E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06120 d567b8c165bc451d77fc7ab6cc5180ae 142 Gene3D G3DSA:1.10.10.10 2 139 4.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_06120 d567b8c165bc451d77fc7ab6cc5180ae 142 SUPERFAMILY SSF46785 5 137 1.46E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_31700 7a3d2f150c2c2bda34f11fc4fdf0c8cf 240 Pfam PF14011 EspG family 1 234 4.9E-60 T 14-10-2018 IPR025734 EspG family A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 SUPERFAMILY SSF51735 26 274 1.6E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 122 7.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 28 45 7.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 172 7.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 201 7.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 238 258 7.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 220 7.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 169 197 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 27 213 2.6E-4 T 14-10-2018 A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 201 8.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 170 8.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 111 122 8.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 33 273 1.6E-64 T 14-10-2018 A4R43_07365 fd782c52ab588b3518311d4f987c7f47 277 Gene3D G3DSA:3.40.50.720 18 276 8.8E-80 T 14-10-2018 A4R43_36410 bbdc75af6ea09d31aa8d171e4fdd3be2 471 Pfam PF07690 Major Facilitator Superfamily 15 408 1.9E-51 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_36410 bbdc75af6ea09d31aa8d171e4fdd3be2 471 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 420 4.5E-74 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4R43_36410 bbdc75af6ea09d31aa8d171e4fdd3be2 471 SUPERFAMILY SSF103473 5 465 4.05E-63 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_36410 bbdc75af6ea09d31aa8d171e4fdd3be2 471 Gene3D G3DSA:1.20.1720.10 10 223 3.2E-45 T 14-10-2018 A4R43_36410 bbdc75af6ea09d31aa8d171e4fdd3be2 471 Gene3D G3DSA:1.20.1250.20 257 468 2.0E-17 T 14-10-2018 A4R43_05955 c70282d59322298624da17568d9fe840 322 SUPERFAMILY SSF51679 3 306 4.45E-54 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_05955 c70282d59322298624da17568d9fe840 322 Pfam PF00296 Luciferase-like monooxygenase 5 297 6.7E-49 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_05955 c70282d59322298624da17568d9fe840 322 Gene3D G3DSA:3.20.20.30 3 318 1.8E-68 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_40970 ae6291bc35a81231cb848cd1f31604da 287 Gene3D G3DSA:3.90.25.10 136 267 1.9E-87 T 14-10-2018 A4R43_40970 ae6291bc35a81231cb848cd1f31604da 287 Pfam PF13460 NAD(P)H-binding 7 182 2.4E-23 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_40970 ae6291bc35a81231cb848cd1f31604da 287 SUPERFAMILY SSF51735 2 271 7.14E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_40970 ae6291bc35a81231cb848cd1f31604da 287 Gene3D G3DSA:3.40.50.720 4 266 1.9E-87 T 14-10-2018 A4R43_06215 057f396c21fa71f75554754412b0cc61 285 Gene3D G3DSA:3.40.50.720 1 282 3.1E-81 T 14-10-2018 A4R43_06215 057f396c21fa71f75554754412b0cc61 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 176 204 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_06215 057f396c21fa71f75554754412b0cc61 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 189 208 3.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06215 057f396c21fa71f75554754412b0cc61 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 128 3.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06215 057f396c21fa71f75554754412b0cc61 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 177 3.1E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06215 057f396c21fa71f75554754412b0cc61 285 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 50 279 4.0E-53 T 14-10-2018 A4R43_06215 057f396c21fa71f75554754412b0cc61 285 SUPERFAMILY SSF51735 40 281 1.79E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_06215 057f396c21fa71f75554754412b0cc61 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 42 59 4.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06215 057f396c21fa71f75554754412b0cc61 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 208 4.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06215 057f396c21fa71f75554754412b0cc61 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 227 4.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06215 057f396c21fa71f75554754412b0cc61 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 128 4.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06215 057f396c21fa71f75554754412b0cc61 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 244 264 4.5E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_39355 baecae71f7ab5ce9cf93715149b79ef5 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 6 21 5.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39355 baecae71f7ab5ce9cf93715149b79ef5 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 5.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39355 baecae71f7ab5ce9cf93715149b79ef5 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 5.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39355 baecae71f7ab5ce9cf93715149b79ef5 116 SMART SM00418 4 82 2.5E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_39355 baecae71f7ab5ce9cf93715149b79ef5 116 SUPERFAMILY SSF46785 3 105 6.3E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_39355 baecae71f7ab5ce9cf93715149b79ef5 116 Pfam PF12840 Helix-turn-helix domain 3 62 4.1E-14 T 14-10-2018 A4R43_39355 baecae71f7ab5ce9cf93715149b79ef5 116 Gene3D G3DSA:1.10.10.10 2 103 5.0E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27040 bc583fa044e15b8ec5b8d2a0eaf2fa98 272 Gene3D G3DSA:1.20.1440.100 26 101 1.0E-66 T 14-10-2018 A4R43_27040 bc583fa044e15b8ec5b8d2a0eaf2fa98 272 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 14 213 1.6E-60 T 14-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like A4R43_27040 bc583fa044e15b8ec5b8d2a0eaf2fa98 272 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 200 1.2E-33 T 14-10-2018 A4R43_27040 bc583fa044e15b8ec5b8d2a0eaf2fa98 272 SUPERFAMILY SSF56784 11 223 2.21E-27 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_27040 bc583fa044e15b8ec5b8d2a0eaf2fa98 272 Gene3D G3DSA:3.40.50.1000 15 226 1.0E-66 T 14-10-2018 IPR023214 HAD superfamily A4R43_27040 bc583fa044e15b8ec5b8d2a0eaf2fa98 272 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 14 201 7.0E-19 T 14-10-2018 A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 Pfam PF00106 short chain dehydrogenase 6 193 1.0E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.0E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.0E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.0E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.0E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.0E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 SUPERFAMILY SSF51735 5 236 1.41E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 Gene3D G3DSA:3.40.50.720 6 248 7.2E-66 T 14-10-2018 A4R43_37880 b09fd9c3349e0843f76c883a9ac284bf 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_37055 892133cc47b38ee3def95fee3c19cb9d 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 103 5.7E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_37055 892133cc47b38ee3def95fee3c19cb9d 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 103 119 5.7E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4R43_37055 892133cc47b38ee3def95fee3c19cb9d 290 Gene3D G3DSA:1.10.10.60 18 71 2.4E-15 T 14-10-2018 A4R43_37055 892133cc47b38ee3def95fee3c19cb9d 290 Pfam PF12833 Helix-turn-helix domain 42 119 7.6E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_37055 892133cc47b38ee3def95fee3c19cb9d 290 SUPERFAMILY SSF46689 72 123 6.27E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_37055 892133cc47b38ee3def95fee3c19cb9d 290 Gene3D G3DSA:1.10.10.60 72 123 1.6E-14 T 14-10-2018 A4R43_37055 892133cc47b38ee3def95fee3c19cb9d 290 SUPERFAMILY SSF46689 20 70 1.7E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_37055 892133cc47b38ee3def95fee3c19cb9d 290 SMART SM00342 36 119 2.4E-31 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 SMART SM00421 138 195 5.5E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 SUPERFAMILY SSF52172 2 129 7.97E-33 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 SUPERFAMILY SSF46894 131 201 3.4E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 SMART SM00448 2 115 5.8E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 Pfam PF00072 Response regulator receiver domain 4 116 3.9E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_39785 127a4dd556ad19b0669c80c9f3572f4f 201 Gene3D G3DSA:3.40.50.12740 2 200 5.0E-60 T 14-10-2018 A4R43_04110 6d4a534e174b2bc17f303efff3301e6f 690 Pfam PF01032 FecCD transport family 24 338 1.5E-68 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_04110 6d4a534e174b2bc17f303efff3301e6f 690 Pfam PF01032 FecCD transport family 376 681 7.6E-83 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_04110 6d4a534e174b2bc17f303efff3301e6f 690 SUPERFAMILY SSF81345 360 681 2.48E-72 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_04110 6d4a534e174b2bc17f303efff3301e6f 690 SUPERFAMILY SSF81345 11 337 7.06E-56 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_04110 6d4a534e174b2bc17f303efff3301e6f 690 Gene3D G3DSA:1.10.3470.10 361 686 5.3E-87 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_04110 6d4a534e174b2bc17f303efff3301e6f 690 Gene3D G3DSA:1.10.3470.10 10 344 4.1E-75 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_17535 51418a67ef23c4015d18067fefb35807 144 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 103 6.2E-19 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A4R43_17535 51418a67ef23c4015d18067fefb35807 144 Gene3D G3DSA:3.40.140.10 1 134 2.1E-29 T 14-10-2018 A4R43_17535 51418a67ef23c4015d18067fefb35807 144 SUPERFAMILY SSF53927 3 130 3.01E-26 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_37720 f7a7a5c8929a0e273264dcd833ca1df7 383 Pfam PF00144 Beta-lactamase 14 363 4.5E-59 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_37720 f7a7a5c8929a0e273264dcd833ca1df7 383 Gene3D G3DSA:3.40.710.10 8 375 3.4E-91 T 14-10-2018 A4R43_37720 f7a7a5c8929a0e273264dcd833ca1df7 383 SUPERFAMILY SSF56601 6 374 3.29E-74 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_18970 9a0933cff694b4034d4590d0d2865c9e 332 SUPERFAMILY SSF51126 62 278 1.47E-5 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor A4R43_17665 dcce55aeb59d659126da5e4349e0d7c0 174 Gene3D G3DSA:1.10.10.10 1 88 3.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17665 dcce55aeb59d659126da5e4349e0d7c0 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 3.8E-15 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_17665 dcce55aeb59d659126da5e4349e0d7c0 174 SUPERFAMILY SSF46785 5 168 1.63E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15910 e11f46fbb1c74dfc6a69ba8f6e7540b4 351 Gene3D G3DSA:3.40.47.10 2 350 4.2E-53 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_15910 e11f46fbb1c74dfc6a69ba8f6e7540b4 351 PIRSF PIRSF000429 1 350 4.3E-18 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_15910 e11f46fbb1c74dfc6a69ba8f6e7540b4 351 SUPERFAMILY SSF53901 24 331 9.6E-17 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_08700 63be20c8c1d8f34b5d63b842e9fd2ab4 352 Pfam PF01757 Acyltransferase family 8 327 6.9E-19 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 SUPERFAMILY SSF51445 17 467 1.5E-153 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 TIGRFAM TIGR03356 BGL: beta-galactosidase 18 457 3.4E-172 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 Gene3D G3DSA:3.20.20.80 11 467 6.7E-170 T 14-10-2018 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 14-10-2018 IPR018120 Glycoside hydrolase family 1, active site A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 Pfam PF00232 Glycosyl hydrolase family 1 17 465 3.8E-146 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 4.6E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 298 312 4.6E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 4.6E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 4.6E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 4.6E-21 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4R43_06450 a993db5d3b788e3bcc7c4a7b2e8b5484 472 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 22 36 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A4R43_10695 dbd839f63eafcc9454cc235a49fafd5b 120 Pfam PF14230 Domain of unknown function (DUF4333) 46 112 4.2E-17 T 14-10-2018 IPR025637 Domain of unknown function DUF4333 A4R43_09705 30176192e9168105168cf9ecb1c433c1 99 Pfam PF07561 Domain of Unknown Function (DUF1540) 62 92 0.006 T 14-10-2018 IPR011437 Domain of unknown function DUF1540 A4R43_09705 30176192e9168105168cf9ecb1c433c1 99 Pfam PF07561 Domain of Unknown Function (DUF1540) 11 43 2.6E-4 T 14-10-2018 IPR011437 Domain of unknown function DUF1540 A4R43_32980 ea5c246368f6c971d3e51e6f75ab9f20 324 Pfam PF01578 Cytochrome C assembly protein 110 318 4.1E-48 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A4R43_32980 ea5c246368f6c971d3e51e6f75ab9f20 324 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 87 321 7.1E-75 T 14-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 A4R43_01120 2b625b69b3fcaf7aa6cd0f365eed6885 152 Pfam PF05119 Phage terminase, small subunit 46 137 4.4E-19 T 14-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family A4R43_01120 2b625b69b3fcaf7aa6cd0f365eed6885 152 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 37 143 6.6E-19 T 14-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family A4R43_06980 83272c1ee246af5f796c56ff4d16df6e 317 SUPERFAMILY SSF51735 28 278 6.13E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_06980 83272c1ee246af5f796c56ff4d16df6e 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 101 112 1.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06980 83272c1ee246af5f796c56ff4d16df6e 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 220 1.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06980 83272c1ee246af5f796c56ff4d16df6e 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 32 49 1.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_06980 83272c1ee246af5f796c56ff4d16df6e 317 Gene3D G3DSA:3.40.50.720 23 315 1.3E-69 T 14-10-2018 A4R43_06980 83272c1ee246af5f796c56ff4d16df6e 317 Pfam PF00106 short chain dehydrogenase 31 225 6.0E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_03045 88c576f2eb1f3ac17a44962e692c8567 148 SUPERFAMILY SSF50475 38 148 2.44E-6 T 14-10-2018 A4R43_03045 88c576f2eb1f3ac17a44962e692c8567 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 37 145 6.3E-31 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_03045 88c576f2eb1f3ac17a44962e692c8567 148 Gene3D G3DSA:2.30.110.10 3 147 8.6E-51 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_03045 88c576f2eb1f3ac17a44962e692c8567 148 Pfam PF04075 F420H(2)-dependent quinone reductase 17 146 2.2E-40 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_37840 2104b900ecdbec6daf4db824462c1c02 64 SUPERFAMILY SSF160582 1 64 2.48E-31 T 14-10-2018 IPR038020 MbtH-like domain superfamily A4R43_37840 2104b900ecdbec6daf4db824462c1c02 64 Gene3D G3DSA:3.90.820.10 1 64 7.4E-36 T 14-10-2018 A4R43_37840 2104b900ecdbec6daf4db824462c1c02 64 Pfam PF03621 MbtH-like protein 1 52 1.6E-30 T 14-10-2018 IPR005153 MbtH-like domain A4R43_37840 2104b900ecdbec6daf4db824462c1c02 64 SMART SM00923 3 53 8.0E-34 T 14-10-2018 IPR005153 MbtH-like domain A4R43_23295 1c76d603fb114ea9ccbd363d9840d22b 153 SUPERFAMILY SSF55486 34 151 4.03E-25 T 14-10-2018 A4R43_23295 1c76d603fb114ea9ccbd363d9840d22b 153 Pfam PF06262 Zincin-like metallopeptidase 60 150 6.8E-11 T 14-10-2018 IPR010428 Zincin-like metallopeptidase A4R43_23295 1c76d603fb114ea9ccbd363d9840d22b 153 Gene3D G3DSA:3.30.2010.20 32 152 1.3E-12 T 14-10-2018 IPR038555 Zincin-like metallopeptidase superfamily A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 Gene3D G3DSA:3.30.540.10 3 140 6.2E-33 T 14-10-2018 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 SUPERFAMILY SSF56655 6 262 1.7E-60 T 14-10-2018 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 Gene3D G3DSA:3.40.190.80 142 276 2.7E-28 T 14-10-2018 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 Pfam PF00459 Inositol monophosphatase family 8 250 2.5E-52 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 1.0E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 1.0E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 131 154 1.0E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.0E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 1.0E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 1.0E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4R43_24590 c6d4970e2d42433b70676233fd79ce7a 291 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4R43_16515 a2631db81af4e7935ac64af194569d03 253 Pfam PF13490 Putative zinc-finger 7 37 6.0E-7 T 14-10-2018 IPR027383 Putative zinc-finger A4R43_16515 a2631db81af4e7935ac64af194569d03 253 Gene3D G3DSA:1.10.10.1320 1 72 9.9E-25 T 14-10-2018 A4R43_16515 a2631db81af4e7935ac64af194569d03 253 Pfam PF10099 Anti-sigma-K factor rskA 58 246 9.1E-34 T 14-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00463 E-class P450 group I signature 43 62 9.8E-24 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00463 E-class P450 group I signature 258 275 9.8E-24 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00463 E-class P450 group I signature 405 428 9.8E-24 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00463 E-class P450 group I signature 395 405 9.8E-24 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00463 E-class P450 group I signature 278 304 9.8E-24 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00463 E-class P450 group I signature 360 384 9.8E-24 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 SUPERFAMILY SSF48264 12 455 1.7E-113 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 Gene3D G3DSA:1.10.630.10 14 457 6.9E-123 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00385 P450 superfamily signature 405 416 3.5E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00385 P450 superfamily signature 321 332 3.5E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00385 P450 superfamily signature 269 286 3.5E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 PRINTS PR00385 P450 superfamily signature 396 405 3.5E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 Pfam PF00067 Cytochrome P450 16 437 6.3E-84 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_37080 ac80c48cc98685e60d218a475578e8e6 458 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 398 407 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_04510 79ebb276d3050d106069d9e96912117c 278 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 273 24.168 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_04510 79ebb276d3050d106069d9e96912117c 278 Pfam PF01259 SAICAR synthetase 4 248 4.4E-93 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_04510 79ebb276d3050d106069d9e96912117c 278 Gene3D G3DSA:3.30.200.20 1 84 4.4E-27 T 14-10-2018 A4R43_04510 79ebb276d3050d106069d9e96912117c 278 SUPERFAMILY SSF56104 1 276 4.58E-91 T 14-10-2018 A4R43_04510 79ebb276d3050d106069d9e96912117c 278 Gene3D G3DSA:3.30.470.20 85 229 1.5E-54 T 14-10-2018 A4R43_04510 79ebb276d3050d106069d9e96912117c 278 ProSitePatterns PS01058 SAICAR synthetase signature 2. 185 193 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4R43_04510 79ebb276d3050d106069d9e96912117c 278 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 276 5.0E-65 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A4R43_13405 f243bf6347fb4af7dfa0848c8bec68dc 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 272 2.0E-23 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_19285 1a5f9a76e795bbe380b264c586d1679f 179 Gene3D G3DSA:3.10.20.30 1 74 1.3E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_19285 1a5f9a76e795bbe380b264c586d1679f 179 Gene3D G3DSA:1.10.150.120 75 171 2.0E-35 T 14-10-2018 A4R43_19285 1a5f9a76e795bbe380b264c586d1679f 179 Pfam PF01799 [2Fe-2S] binding domain 73 145 9.6E-31 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4R43_19285 1a5f9a76e795bbe380b264c586d1679f 179 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 57 1.2E-5 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_19285 1a5f9a76e795bbe380b264c586d1679f 179 SUPERFAMILY SSF47741 84 155 7.07E-34 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4R43_19285 1a5f9a76e795bbe380b264c586d1679f 179 SUPERFAMILY SSF54292 2 78 1.02E-21 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_15540 1008da72281a73b8475da144d019521a 211 Pfam PF03167 Uracil DNA glycosylase superfamily 39 205 8.4E-39 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_15540 1008da72281a73b8475da144d019521a 211 Gene3D G3DSA:3.40.470.10 2 211 2.1E-59 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_15540 1008da72281a73b8475da144d019521a 211 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 9 206 1.3E-75 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 A4R43_15540 1008da72281a73b8475da144d019521a 211 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 25 198 2.8E-39 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 A4R43_15540 1008da72281a73b8475da144d019521a 211 SMART SM00986 39 205 5.5E-38 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_15540 1008da72281a73b8475da144d019521a 211 SUPERFAMILY SSF52141 14 209 1.31E-51 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4R43_15540 1008da72281a73b8475da144d019521a 211 SMART SM00987 39 205 5.5E-38 T 14-10-2018 A4R43_32280 b131ee07d879198225a9bf4f47a72311 478 Gene3D G3DSA:1.10.260.150 157 456 1.0E-66 T 14-10-2018 A4R43_32280 b131ee07d879198225a9bf4f47a72311 478 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 201 365 5.1E-41 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_32280 b131ee07d879198225a9bf4f47a72311 478 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 200 366 3.7E-48 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A4R43_27055 d3dbaebb25de4c43ea84a7e1d13a0438 578 Pfam PF00144 Beta-lactamase 85 406 5.3E-71 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_27055 d3dbaebb25de4c43ea84a7e1d13a0438 578 SUPERFAMILY SSF56601 82 406 6.04E-84 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_27055 d3dbaebb25de4c43ea84a7e1d13a0438 578 Gene3D G3DSA:3.40.710.10 36 416 8.8E-88 T 14-10-2018 A4R43_32755 bc8cdb502dae5965cc7576beb2eac438 170 Gene3D G3DSA:3.30.1460.10 2 135 6.0E-7 T 14-10-2018 A4R43_32755 bc8cdb502dae5965cc7576beb2eac438 170 SUPERFAMILY SSF69635 3 128 5.89E-30 T 14-10-2018 A4R43_32755 bc8cdb502dae5965cc7576beb2eac438 170 Pfam PF10722 Putative bacterial sensory transduction regulator 6 126 7.9E-25 T 14-10-2018 IPR019660 Putative sensory transduction regulator YbjN A4R43_02870 f3b9ed0334e9d71a32f4fee085b3cb65 140 Pfam PF14342 Domain of unknown function (DUF4396) 1 130 6.7E-43 T 14-10-2018 IPR025509 Domain of unknown function DUF4396 A4R43_38355 b967425895fcf09b405d3fb1f3c66924 144 Gene3D G3DSA:3.30.750.24 8 122 5.1E-28 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_38355 b967425895fcf09b405d3fb1f3c66924 144 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 13 111 8.5E-20 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_38355 b967425895fcf09b405d3fb1f3c66924 144 Pfam PF01740 STAS domain 24 111 8.4E-10 T 14-10-2018 IPR002645 STAS domain A4R43_38355 b967425895fcf09b405d3fb1f3c66924 144 SUPERFAMILY SSF52091 13 117 6.08E-18 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_33115 59e7806b3611663766e84f8beac72832 443 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 21 353 24.534 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33115 59e7806b3611663766e84f8beac72832 443 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 231 244 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33115 59e7806b3611663766e84f8beac72832 443 Pfam PF00146 NADH dehydrogenase 28 346 1.0E-125 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_17435 b46bb2ca710255433bd4594f6f25075e 103 SUPERFAMILY SSF52091 5 101 1.1E-22 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_17435 b46bb2ca710255433bd4594f6f25075e 103 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 5 101 2.0E-20 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4R43_17435 b46bb2ca710255433bd4594f6f25075e 103 Gene3D G3DSA:3.30.750.24 4 103 3.9E-27 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_17435 b46bb2ca710255433bd4594f6f25075e 103 Pfam PF13466 STAS domain 20 95 1.5E-19 T 14-10-2018 IPR002645 STAS domain A4R43_32190 eb4f2557eee247c6d45139423365b3c2 193 Gene3D G3DSA:3.40.50.1820 3 182 7.6E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_32190 eb4f2557eee247c6d45139423365b3c2 193 SUPERFAMILY SSF53474 7 144 5.21E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_30020 6ce5767e6f8c634cba41228f64397733 489 Pfam PF01609 Transposase DDE domain 160 429 2.0E-16 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4R43_30020 6ce5767e6f8c634cba41228f64397733 489 SUPERFAMILY SSF53098 226 454 2.05E-9 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_38530 11333750ce03f8d06ed96bcc7472b7e9 357 Gene3D G3DSA:3.40.50.720 1 122 2.6E-20 T 14-10-2018 A4R43_38530 11333750ce03f8d06ed96bcc7472b7e9 357 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 116 3.1E-15 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4R43_38530 11333750ce03f8d06ed96bcc7472b7e9 357 Gene3D G3DSA:3.30.360.10 126 351 6.5E-28 T 14-10-2018 A4R43_38530 11333750ce03f8d06ed96bcc7472b7e9 357 SUPERFAMILY SSF51735 3 154 1.6E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38530 11333750ce03f8d06ed96bcc7472b7e9 357 SUPERFAMILY SSF55347 139 321 4.91E-21 T 14-10-2018 A4R43_28345 b6a779bf445ffa5066e781417a0e5184 315 Pfam PF12079 Protein of unknown function (DUF3558) 11 164 2.5E-12 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_28345 b6a779bf445ffa5066e781417a0e5184 315 Pfam PF12079 Protein of unknown function (DUF3558) 172 312 2.2E-8 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_19840 73c47eb6d224a47a2c5dfc0c0336e13a 411 Gene3D G3DSA:3.40.710.30 7 411 1.0E-129 T 14-10-2018 A4R43_19840 73c47eb6d224a47a2c5dfc0c0336e13a 411 SUPERFAMILY SSF56601 13 406 1.34E-73 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_19840 73c47eb6d224a47a2c5dfc0c0336e13a 411 Pfam PF00144 Beta-lactamase 23 403 1.9E-71 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_10655 6ffe5a3d254c23d928fd9d422be7c088 214 SUPERFAMILY SSF46689 22 101 2.41E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_10655 6ffe5a3d254c23d928fd9d422be7c088 214 Gene3D G3DSA:1.10.357.10 68 210 1.5E-31 T 14-10-2018 A4R43_10655 6ffe5a3d254c23d928fd9d422be7c088 214 Gene3D G3DSA:1.10.10.60 19 67 1.3E-13 T 14-10-2018 A4R43_10655 6ffe5a3d254c23d928fd9d422be7c088 214 SUPERFAMILY SSF48498 98 208 1.94E-22 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_28570 a35f62b7a3c5b51787e0468b543dbf4a 250 Pfam PF05988 Bacterial protein of unknown function (DUF899) 5 202 2.1E-58 T 14-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like A4R43_08235 6e4cb6e3e32cf49d6638a5c967148f0c 150 Gene3D G3DSA:1.10.10.10 5 141 1.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08235 6e4cb6e3e32cf49d6638a5c967148f0c 150 SUPERFAMILY SSF46785 7 139 4.08E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08235 6e4cb6e3e32cf49d6638a5c967148f0c 150 SMART SM00347 27 127 9.5E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_08235 6e4cb6e3e32cf49d6638a5c967148f0c 150 Pfam PF12802 MarR family 34 91 5.0E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_08235 6e4cb6e3e32cf49d6638a5c967148f0c 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 100 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_20250 82c20cefd70211bb195a6f9264cedc09 378 SUPERFAMILY SSF53955 87 210 6.75E-10 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_20250 82c20cefd70211bb195a6f9264cedc09 378 Gene3D G3DSA:3.90.1720.10 178 368 4.0E-36 T 14-10-2018 A4R43_20250 82c20cefd70211bb195a6f9264cedc09 378 SUPERFAMILY SSF54001 249 364 8.34E-31 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_20250 82c20cefd70211bb195a6f9264cedc09 378 Pfam PF00877 NlpC/P60 family 267 364 7.6E-22 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A4R43_03390 96477979f36ce6e297eff323bb956a33 143 Gene3D G3DSA:2.60.40.790 1 133 4.6E-31 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_03390 96477979f36ce6e297eff323bb956a33 143 SUPERFAMILY SSF49764 5 132 4.19E-32 T 14-10-2018 IPR008978 HSP20-like chaperone A4R43_03390 96477979f36ce6e297eff323bb956a33 143 Pfam PF00011 Hsp20/alpha crystallin family 36 132 1.1E-19 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4R43_24385 e3ea26d62cad9fa8b4da60658dd83264 224 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 75 217 1.3E-19 T 14-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase A4R43_07535 3c3b66ab7f14fb046635ce9d7407e0a8 311 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 152 265 2.1E-26 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 A4R43_07535 3c3b66ab7f14fb046635ce9d7407e0a8 311 SUPERFAMILY SSF53756 4 304 8.47E-59 T 14-10-2018 A4R43_07535 3c3b66ab7f14fb046635ce9d7407e0a8 311 Gene3D G3DSA:3.40.50.2000 145 307 4.2E-39 T 14-10-2018 A4R43_07535 3c3b66ab7f14fb046635ce9d7407e0a8 311 Gene3D G3DSA:3.40.50.2000 3 69 7.1E-7 T 14-10-2018 A4R43_13335 47d7ed3a472bf64b6c2a2bef6d1de2ae 119 Gene3D G3DSA:1.10.10.10 1 118 2.1E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_13335 47d7ed3a472bf64b6c2a2bef6d1de2ae 119 Pfam PF01638 HxlR-like helix-turn-helix 20 110 1.7E-24 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_13335 47d7ed3a472bf64b6c2a2bef6d1de2ae 119 SUPERFAMILY SSF46785 5 114 1.04E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 ProSitePatterns PS00079 Multicopper oxidases signature 1. 499 519 - T 14-10-2018 IPR033138 Multicopper oxidases, conserved site A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 SUPERFAMILY SSF49503 50 214 2.41E-21 T 14-10-2018 IPR008972 Cupredoxin A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 Pfam PF07732 Multicopper oxidase 82 140 1.3E-10 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 SUPERFAMILY SSF49503 217 349 2.29E-22 T 14-10-2018 IPR008972 Cupredoxin A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 Pfam PF07731 Multicopper oxidase 418 520 4.0E-23 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 Gene3D G3DSA:2.60.40.420 388 522 4.8E-41 T 14-10-2018 IPR008972 Cupredoxin A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 SUPERFAMILY SSF49503 400 519 1.96E-29 T 14-10-2018 IPR008972 Cupredoxin A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 Gene3D G3DSA:2.60.40.420 211 387 8.3E-53 T 14-10-2018 IPR008972 Cupredoxin A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 ProSitePatterns PS00080 Multicopper oxidases signature 2. 504 515 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 Gene3D G3DSA:2.60.40.420 41 120 1.4E-15 T 14-10-2018 IPR008972 Cupredoxin A4R43_19750 4841dd196e66c7eef2329202b724dee9 522 Gene3D G3DSA:2.60.40.420 121 210 1.4E-22 T 14-10-2018 IPR008972 Cupredoxin A4R43_04360 c81e637cad5b106a9fda4e2468e346c1 259 Gene3D G3DSA:1.10.12.10 203 259 9.4E-15 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_04360 c81e637cad5b106a9fda4e2468e346c1 259 Gene3D G3DSA:3.90.226.10 1 201 3.6E-63 T 14-10-2018 A4R43_04360 c81e637cad5b106a9fda4e2468e346c1 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 1.3E-45 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_04360 c81e637cad5b106a9fda4e2468e346c1 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A4R43_04360 c81e637cad5b106a9fda4e2468e346c1 259 SUPERFAMILY SSF52096 5 257 5.41E-69 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_15680 dc40908226aedbc580daa8c7fcc55f90 316 PIRSF PIRSF001365 6 311 5.4E-48 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_15680 dc40908226aedbc580daa8c7fcc55f90 316 SMART SM01130 10 306 1.8E-55 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_15680 dc40908226aedbc580daa8c7fcc55f90 316 Pfam PF00701 Dihydrodipicolinate synthetase family 11 304 4.9E-42 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_15680 dc40908226aedbc580daa8c7fcc55f90 316 SUPERFAMILY SSF51569 9 304 8.79E-57 T 14-10-2018 A4R43_15680 dc40908226aedbc580daa8c7fcc55f90 316 Gene3D G3DSA:3.20.20.70 3 308 2.2E-75 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_15680 dc40908226aedbc580daa8c7fcc55f90 316 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 10 307 42.105 T 14-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 A4R43_14120 f566ccae8a96ddba43a3ad38c72d46c8 219 SUPERFAMILY SSF48498 101 206 3.62E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_14120 f566ccae8a96ddba43a3ad38c72d46c8 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 73 4.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14120 f566ccae8a96ddba43a3ad38c72d46c8 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 7.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14120 f566ccae8a96ddba43a3ad38c72d46c8 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 7.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14120 f566ccae8a96ddba43a3ad38c72d46c8 219 SUPERFAMILY SSF46689 18 95 3.23E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14120 f566ccae8a96ddba43a3ad38c72d46c8 219 Gene3D G3DSA:1.10.357.10 70 208 5.7E-15 T 14-10-2018 A4R43_14120 f566ccae8a96ddba43a3ad38c72d46c8 219 Gene3D G3DSA:1.10.10.60 5 69 1.0E-13 T 14-10-2018 A4R43_39700 d48a5eeaf18db0fb7b81dcfd129eb40f 155 Pfam PF04505 Interferon-induced transmembrane protein 56 120 3.4E-13 T 14-10-2018 IPR007593 CD225/Dispanin family GO:0016021 A4R43_15530 9f5a1ad63e8dd8e8e72e1d8c8906c4c3 435 Pfam PF04434 SWIM zinc finger 66 86 1.4E-5 T 14-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A4R43_06830 2c376f335912cd5473ed8e3812ce9e25 486 SUPERFAMILY SSF51905 1 486 1.03E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_06830 2c376f335912cd5473ed8e3812ce9e25 486 SUPERFAMILY SSF56425 290 432 6.63E-27 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_06830 2c376f335912cd5473ed8e3812ce9e25 486 Gene3D G3DSA:3.50.50.60 4 484 5.3E-117 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_06830 2c376f335912cd5473ed8e3812ce9e25 486 Pfam PF00890 FAD binding domain 5 469 2.1E-50 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_06830 2c376f335912cd5473ed8e3812ce9e25 486 Gene3D G3DSA:3.90.700.10 258 428 5.3E-117 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4R43_09260 5b4edae95b7fab54a620dc9884fdedd8 1222 SUPERFAMILY SSF53335 76 494 2.72E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_09260 5b4edae95b7fab54a620dc9884fdedd8 1222 Gene3D G3DSA:3.40.50.150 195 507 5.9E-37 T 14-10-2018 A4R43_09260 5b4edae95b7fab54a620dc9884fdedd8 1222 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 378 384 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4R43_09260 5b4edae95b7fab54a620dc9884fdedd8 1222 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 212 228 1.2E-6 T 14-10-2018 A4R43_09260 5b4edae95b7fab54a620dc9884fdedd8 1222 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 243 257 1.2E-6 T 14-10-2018 A4R43_09260 5b4edae95b7fab54a620dc9884fdedd8 1222 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 375 387 1.2E-6 T 14-10-2018 A4R43_16485 bf9473900eb3d5621d5f6bed818994e3 286 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 7.3E-15 T 14-10-2018 IPR019933 DivIVA domain A4R43_16485 bf9473900eb3d5621d5f6bed818994e3 286 Pfam PF05103 DivIVA protein 3 67 2.1E-12 T 14-10-2018 IPR007793 DivIVA family A4R43_20780 7f5deba94b26decaf5d185f506d8caad 308 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 41 54 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4R43_20780 7f5deba94b26decaf5d185f506d8caad 308 SUPERFAMILY SSF53686 11 298 3.67E-70 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_20780 7f5deba94b26decaf5d185f506d8caad 308 Gene3D G3DSA:3.40.50.1100 31 299 2.9E-85 T 14-10-2018 A4R43_20780 7f5deba94b26decaf5d185f506d8caad 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 31 295 1.3E-68 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_20780 7f5deba94b26decaf5d185f506d8caad 308 Gene3D G3DSA:3.40.50.1100 49 139 2.9E-85 T 14-10-2018 A4R43_41595 6200c7ac455766a430ac58a7e6b08877 296 Gene3D G3DSA:3.40.50.1820 1 285 2.7E-72 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41595 6200c7ac455766a430ac58a7e6b08877 296 SUPERFAMILY SSF53474 3 281 3.54E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_41595 6200c7ac455766a430ac58a7e6b08877 296 Pfam PF12146 Serine aminopeptidase, S33 31 268 5.0E-18 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 A4R43_31445 ec0eec7ec7da093d60d957c81ec2fdea 187 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 23 184 9.9E-36 T 14-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_31445 ec0eec7ec7da093d60d957c81ec2fdea 187 SUPERFAMILY SSF53271 17 184 3.15E-32 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_31445 ec0eec7ec7da093d60d957c81ec2fdea 187 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 187 24.026 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4R43_31445 ec0eec7ec7da093d60d957c81ec2fdea 187 Gene3D G3DSA:3.40.50.2020 5 187 2.9E-48 T 14-10-2018 A4R43_31445 ec0eec7ec7da093d60d957c81ec2fdea 187 Pfam PF00156 Phosphoribosyl transferase domain 51 166 1.1E-11 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4R43_19880 868d09349b210ea857259a2a6c38ecf5 111 SUPERFAMILY SSF46785 7 90 1.52E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19880 868d09349b210ea857259a2a6c38ecf5 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 8.7E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_19880 868d09349b210ea857259a2a6c38ecf5 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 8.7E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_19880 868d09349b210ea857259a2a6c38ecf5 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 8.7E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_19880 868d09349b210ea857259a2a6c38ecf5 111 SMART SM00418 17 99 2.7E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_19880 868d09349b210ea857259a2a6c38ecf5 111 Gene3D G3DSA:1.10.10.10 11 103 9.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19880 868d09349b210ea857259a2a6c38ecf5 111 Pfam PF12840 Helix-turn-helix domain 17 75 4.4E-7 T 14-10-2018 A4R43_38405 17bce16f47553f49a78a44126e81d4a0 725 Gene3D G3DSA:1.10.600.10 1 331 1.3E-92 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_38405 17bce16f47553f49a78a44126e81d4a0 725 Gene3D G3DSA:1.10.600.10 363 692 6.5E-90 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_38405 17bce16f47553f49a78a44126e81d4a0 725 SUPERFAMILY SSF48576 3 331 1.58E-64 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_38405 17bce16f47553f49a78a44126e81d4a0 725 SUPERFAMILY SSF48576 369 683 2.79E-62 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 Gene3D G3DSA:3.30.70.141 1 135 2.2E-56 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 SUPERFAMILY SSF54919 3 135 3.01E-53 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 Pfam PF00334 Nucleoside diphosphate kinase 3 134 2.3E-52 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 SMART SM00562 2 135 3.5E-69 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 135 33.241 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.0E-43 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.0E-43 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 1.0E-43 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 1.0E-43 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_39205 ddb4c8e1160c116242d63473faefcbc2 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 1.0E-43 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4R43_26305 1bb3dc8b95375ba2a2c85ce66b5b8d0b 203 Gene3D G3DSA:3.40.50.1820 1 202 1.2E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_26305 1bb3dc8b95375ba2a2c85ce66b5b8d0b 203 SUPERFAMILY SSF53474 8 201 8.63E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_26305 1bb3dc8b95375ba2a2c85ce66b5b8d0b 203 Pfam PF02230 Phospholipase/Carboxylesterase 13 201 6.2E-10 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 A4R43_25160 b6d917895086794c95b68b75c7e07e87 399 Pfam PF12704 MacB-like periplasmic core domain 32 240 5.4E-16 T 14-10-2018 IPR025857 MacB-like periplasmic core domain A4R43_25160 b6d917895086794c95b68b75c7e07e87 399 Pfam PF02687 FtsX-like permease family 304 392 1.0E-9 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_20420 86b19e039f58e013f61f3e9cec298871 259 Gene3D G3DSA:3.90.226.10 1 198 8.8E-68 T 14-10-2018 A4R43_20420 86b19e039f58e013f61f3e9cec298871 259 SUPERFAMILY SSF52096 3 255 1.42E-76 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_20420 86b19e039f58e013f61f3e9cec298871 259 Gene3D G3DSA:1.10.12.10 199 259 8.1E-16 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_20420 86b19e039f58e013f61f3e9cec298871 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 251 2.5E-63 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_10525 790e92f0a2f760064b5b8a71aba100ca 387 PIRSF PIRSF029347 1 387 6.8E-147 T 14-10-2018 IPR014555 RecF-like A4R43_10525 790e92f0a2f760064b5b8a71aba100ca 387 Gene3D G3DSA:3.40.50.300 1 102 1.3E-9 T 14-10-2018 A4R43_10525 790e92f0a2f760064b5b8a71aba100ca 387 Pfam PF13175 AAA ATPase domain 2 49 1.3E-9 T 14-10-2018 A4R43_10525 790e92f0a2f760064b5b8a71aba100ca 387 SUPERFAMILY SSF52540 2 351 3.49E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10525 790e92f0a2f760064b5b8a71aba100ca 387 Gene3D G3DSA:3.40.50.300 241 365 1.4E-8 T 14-10-2018 A4R43_10525 790e92f0a2f760064b5b8a71aba100ca 387 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 208 343 7.7E-19 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4R43_33780 f72312284d16bc3048e66aa192da83e4 282 Gene3D G3DSA:1.10.357.140 7 157 1.4E-12 T 14-10-2018 A4R43_33780 f72312284d16bc3048e66aa192da83e4 282 Pfam PF01040 UbiA prenyltransferase family 36 164 1.4E-17 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A4R43_00245 02799f34dcfca93d861b8ccaddfcfee2 401 Gene3D G3DSA:3.30.1540.10 238 330 5.3E-128 T 14-10-2018 A4R43_00245 02799f34dcfca93d861b8ccaddfcfee2 401 SUPERFAMILY SSF89796 11 400 5.36E-127 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_00245 02799f34dcfca93d861b8ccaddfcfee2 401 Gene3D G3DSA:3.40.50.10540 13 390 5.3E-128 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_00245 02799f34dcfca93d861b8ccaddfcfee2 401 Pfam PF02515 CoA-transferase family III 13 379 1.7E-125 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_16625 44cf7a1eeaf6369fd98985e14b070282 344 Pfam PF02470 MlaD protein 38 110 2.4E-16 T 14-10-2018 IPR003399 Mce/MlaD A4R43_16625 44cf7a1eeaf6369fd98985e14b070282 344 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 291 4.5E-66 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_10500 8875bd21d3c52f5058ae31a925c1e19c 193 Gene3D G3DSA:3.40.430.10 8 184 2.5E-31 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_10500 8875bd21d3c52f5058ae31a925c1e19c 193 Pfam PF01872 RibD C-terminal domain 8 169 1.2E-11 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_10500 8875bd21d3c52f5058ae31a925c1e19c 193 SUPERFAMILY SSF53597 8 170 2.66E-18 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_24355 64a3ff0f6f770bb9b3bdd60e2e382acc 348 Pfam PF00144 Beta-lactamase 3 328 5.0E-57 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_24355 64a3ff0f6f770bb9b3bdd60e2e382acc 348 SUPERFAMILY SSF56601 4 338 1.89E-59 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_24355 64a3ff0f6f770bb9b3bdd60e2e382acc 348 Gene3D G3DSA:3.40.710.30 2 346 3.0E-92 T 14-10-2018 A4R43_10935 8451da41b6ff405764fc3d40756b9122 274 SUPERFAMILY SSF56300 4 255 8.51E-26 T 14-10-2018 A4R43_10935 8451da41b6ff405764fc3d40756b9122 274 Pfam PF00149 Calcineurin-like phosphoesterase 5 239 3.2E-15 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_17220 b4fe38063d3e30fdaf8d20385d803aac 511 Gene3D G3DSA:3.40.190.10 196 492 9.1E-88 T 14-10-2018 A4R43_17220 b4fe38063d3e30fdaf8d20385d803aac 511 Gene3D G3DSA:3.10.105.10 269 482 9.1E-88 T 14-10-2018 A4R43_17220 b4fe38063d3e30fdaf8d20385d803aac 511 PIRSF PIRSF002741 4 510 9.5E-65 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4R43_17220 b4fe38063d3e30fdaf8d20385d803aac 511 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 399 1.0E-65 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain A4R43_17220 b4fe38063d3e30fdaf8d20385d803aac 511 Gene3D G3DSA:3.90.76.10 53 195 9.1E-88 T 14-10-2018 A4R43_17220 b4fe38063d3e30fdaf8d20385d803aac 511 SUPERFAMILY SSF53850 35 507 1.07E-100 T 14-10-2018 A4R43_41400 94593596966a815cb9d4f31a24cd9b7a 248 Pfam PF14011 EspG family 5 243 1.3E-57 T 14-10-2018 IPR025734 EspG family A4R43_08120 a104b9b37c05063a61f19560f55e4f83 111 SUPERFAMILY SSF46785 4 105 3.03E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08120 a104b9b37c05063a61f19560f55e4f83 111 Pfam PF01638 HxlR-like helix-turn-helix 16 104 1.8E-31 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_08120 a104b9b37c05063a61f19560f55e4f83 111 Gene3D G3DSA:1.10.10.10 1 110 1.8E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20020 4e46ff8183ae6a6bebb5491e7ffd1873 302 SUPERFAMILY SSF52283 33 115 3.95E-6 T 14-10-2018 A4R43_20020 4e46ff8183ae6a6bebb5491e7ffd1873 302 Gene3D G3DSA:3.40.50.720 92 274 5.0E-74 T 14-10-2018 A4R43_20020 4e46ff8183ae6a6bebb5491e7ffd1873 302 Gene3D G3DSA:3.40.50.720 19 298 5.0E-74 T 14-10-2018 A4R43_20020 4e46ff8183ae6a6bebb5491e7ffd1873 302 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 101 267 1.4E-44 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4R43_20020 4e46ff8183ae6a6bebb5491e7ffd1873 302 SUPERFAMILY SSF51735 94 268 7.05E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_20020 4e46ff8183ae6a6bebb5491e7ffd1873 302 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 207 223 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4R43_15660 5484059e713a44d3325ffb89bc2eda17 254 SUPERFAMILY SSF53335 35 251 1.22E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_15660 5484059e713a44d3325ffb89bc2eda17 254 Pfam PF08241 Methyltransferase domain 52 139 6.9E-8 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_15660 5484059e713a44d3325ffb89bc2eda17 254 Gene3D G3DSA:3.40.50.150 26 161 3.3E-15 T 14-10-2018 A4R43_13755 732535e3ae3441ca824406d6df85b8c0 220 Pfam PF09335 SNARE associated Golgi protein 59 176 1.5E-23 T 14-10-2018 IPR032816 SNARE associated Golgi protein A4R43_33350 285304305d2f028a74bafe9839733482 371 Gene3D G3DSA:3.40.640.10 1 244 2.2E-89 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_33350 285304305d2f028a74bafe9839733482 371 SUPERFAMILY SSF53383 2 365 6.34E-102 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_33350 285304305d2f028a74bafe9839733482 371 PIRSF PIRSF000390 1 369 1.2E-109 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_33350 285304305d2f028a74bafe9839733482 371 Gene3D G3DSA:3.90.1150.10 245 367 2.8E-27 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_33350 285304305d2f028a74bafe9839733482 371 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 6 361 1.3E-112 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_23390 fb4761eb79caca3cdabd907a93516a86 369 Pfam PF03888 MucB/RseB N-terminal domain 159 220 2.9E-5 T 14-10-2018 IPR033434 MucB/RseB, N-terminal A4R43_23390 fb4761eb79caca3cdabd907a93516a86 369 SUPERFAMILY SSF89392 102 255 7.45E-14 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4R43_23390 fb4761eb79caca3cdabd907a93516a86 369 Gene3D G3DSA:2.50.20.10 79 254 4.0E-20 T 14-10-2018 A4R43_23690 93ad515194bd0eb99955189b4935ab5c 268 SUPERFAMILY SSF56281 59 241 1.4E-25 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_23690 93ad515194bd0eb99955189b4935ab5c 268 SMART SM00849 73 234 1.0E-5 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_23690 93ad515194bd0eb99955189b4935ab5c 268 Gene3D G3DSA:3.60.15.10 35 234 2.6E-12 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_31705 a2eb51a4e06c5e597cfc9937000c7c1b 218 Gene3D G3DSA:1.20.120.450 1 153 1.3E-14 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_31705 a2eb51a4e06c5e597cfc9937000c7c1b 218 SUPERFAMILY SSF109854 2 151 3.97E-11 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_31705 a2eb51a4e06c5e597cfc9937000c7c1b 218 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 149 1.5E-20 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4R43_03255 eb9aacf16a72c8f57aaae4f736026fbd 266 Pfam PF12697 Alpha/beta hydrolase family 23 261 1.0E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_03255 eb9aacf16a72c8f57aaae4f736026fbd 266 Gene3D G3DSA:3.40.50.1820 1 264 1.1E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03255 eb9aacf16a72c8f57aaae4f736026fbd 266 SUPERFAMILY SSF53474 1 262 8.24E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_35950 44ea118fc0183c7a36d639a1a429a88c 103 Gene3D G3DSA:1.10.10.10 2 100 4.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_35950 44ea118fc0183c7a36d639a1a429a88c 103 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 6 79 9.1E-16 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4R43_35950 44ea118fc0183c7a36d639a1a429a88c 103 SUPERFAMILY SSF46767 3 78 1.7E-14 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 SUPERFAMILY SSF118215 21 413 3.66E-106 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 306 329 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 Pfam PF00375 Sodium:dicarboxylate symporter family 21 412 7.6E-99 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 PRINTS PR00173 Glutamate-aspartate symporter signature 56 76 2.0E-30 T 14-10-2018 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 PRINTS PR00173 Glutamate-aspartate symporter signature 156 178 2.0E-30 T 14-10-2018 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 2.0E-30 T 14-10-2018 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 PRINTS PR00173 Glutamate-aspartate symporter signature 86 111 2.0E-30 T 14-10-2018 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 2.0E-30 T 14-10-2018 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 2.0E-30 T 14-10-2018 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 2.0E-30 T 14-10-2018 A4R43_01800 f099292dcda63763d64a3b161e71c6a7 447 Gene3D G3DSA:1.10.3860.10 12 430 1.2E-110 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4R43_13570 9f0c6ce5f46c4f4d6e83aeed58647346 325 SUPERFAMILY SSF50952 24 315 1.96E-36 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4R43_13570 9f0c6ce5f46c4f4d6e83aeed58647346 325 Pfam PF07995 Glucose / Sorbosone dehydrogenase 40 315 2.4E-55 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4R43_13570 9f0c6ce5f46c4f4d6e83aeed58647346 325 Gene3D G3DSA:2.120.10.30 18 322 1.9E-90 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_38995 184047802b62a5e256684655bb4c29c3 332 Gene3D G3DSA:3.40.50.2300 34 316 3.4E-95 T 14-10-2018 A4R43_38995 184047802b62a5e256684655bb4c29c3 332 Gene3D G3DSA:3.40.50.2300 134 332 3.4E-95 T 14-10-2018 A4R43_38995 184047802b62a5e256684655bb4c29c3 332 SUPERFAMILY SSF53822 32 331 7.85E-56 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_38995 184047802b62a5e256684655bb4c29c3 332 Pfam PF13407 Periplasmic binding protein domain 34 290 5.7E-47 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_13475 77bc79d4c7c2021bc32be81588ec77ce 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 270 1.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_13475 77bc79d4c7c2021bc32be81588ec77ce 283 SUPERFAMILY SSF161098 66 251 3.92E-20 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_13475 77bc79d4c7c2021bc32be81588ec77ce 283 Gene3D G3DSA:1.10.3720.10 61 265 5.2E-15 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_13475 77bc79d4c7c2021bc32be81588ec77ce 283 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 47 3.5E-5 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4R43_06405 ad45bd81a1dd0dbb95bf7fa3fe20f1c4 270 Gene3D G3DSA:1.10.3720.10 2 261 2.3E-61 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06405 ad45bd81a1dd0dbb95bf7fa3fe20f1c4 270 SUPERFAMILY SSF161098 5 267 2.22E-66 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06405 ad45bd81a1dd0dbb95bf7fa3fe20f1c4 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 249 3.4E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_05150 c043ab657b9e7332b5c4b5b61d9874cd 411 Pfam PF02353 Mycolic acid cyclopropane synthetase 140 407 6.6E-84 T 14-10-2018 A4R43_05150 c043ab657b9e7332b5c4b5b61d9874cd 411 SUPERFAMILY SSF53335 146 409 8.44E-70 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_05150 c043ab657b9e7332b5c4b5b61d9874cd 411 PIRSF PIRSF003085 27 411 6.4E-115 T 14-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 A4R43_05150 c043ab657b9e7332b5c4b5b61d9874cd 411 Gene3D G3DSA:3.40.50.150 144 411 2.8E-95 T 14-10-2018 A4R43_37060 0523a95b4c2ae106f4f1ab1197d1254a 332 Pfam PF08012 Protein of unknown function (DUF1702) 5 323 3.0E-135 T 14-10-2018 IPR012964 Protein of unknown function DUF1702 A4R43_40435 6b775cb30744d9ac37379f9d346ded0b 342 Pfam PF02720 Domain of unknown function (DUF222) 1 255 3.6E-10 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_32475 f93531f967c49fd7ccc0768586824d6b 380 Pfam PF00149 Calcineurin-like phosphoesterase 157 322 1.3E-13 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_32475 f93531f967c49fd7ccc0768586824d6b 380 SUPERFAMILY SSF56300 157 377 3.14E-40 T 14-10-2018 A4R43_32475 f93531f967c49fd7ccc0768586824d6b 380 Gene3D G3DSA:3.60.21.10 155 354 6.9E-27 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_10155 d6581abeeb01bf2009dcaa2929c96d7e 308 SUPERFAMILY SSF103481 199 298 2.62E-11 T 14-10-2018 A4R43_10155 d6581abeeb01bf2009dcaa2929c96d7e 308 SUPERFAMILY SSF103481 56 152 4.84E-8 T 14-10-2018 A4R43_10155 d6581abeeb01bf2009dcaa2929c96d7e 308 Pfam PF00892 EamA-like transporter family 164 295 5.4E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_10155 d6581abeeb01bf2009dcaa2929c96d7e 308 Pfam PF00892 EamA-like transporter family 21 151 9.9E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_30715 daef8a1b2bc0ebe398e4bc8fcbbf2d46 430 Gene3D G3DSA:3.30.460.10 22 148 1.6E-6 T 14-10-2018 A4R43_30715 daef8a1b2bc0ebe398e4bc8fcbbf2d46 430 SUPERFAMILY SSF81301 3 142 8.5E-17 T 14-10-2018 A4R43_21370 0b6c82c2cd695b4e91f98f729843ca70 285 Pfam PF15575 Immunity protein 49 57 271 1.9E-48 T 14-10-2018 IPR029074 Immunity protein 49 A4R43_21930 6e8a22e2a7e37fa8ecb5078ae6829d90 123 Gene3D G3DSA:3.10.180.10 3 118 3.3E-30 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_21930 6e8a22e2a7e37fa8ecb5078ae6829d90 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 115 2.6E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_21930 6e8a22e2a7e37fa8ecb5078ae6829d90 123 SUPERFAMILY SSF54593 6 119 1.88E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_09410 12a49c853a9e36fb469e4058c503733a 496 SUPERFAMILY SSF75005 222 471 6.11E-8 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_09410 12a49c853a9e36fb469e4058c503733a 496 Gene3D G3DSA:2.115.10.20 220 491 5.4E-7 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_41100 6ca99be729e6da908de9a7a96f6bb70c 196 SUPERFAMILY SSF46785 11 168 4.43E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_41100 6ca99be729e6da908de9a7a96f6bb70c 196 Pfam PF12840 Helix-turn-helix domain 15 67 5.5E-13 T 14-10-2018 A4R43_41100 6ca99be729e6da908de9a7a96f6bb70c 196 Gene3D G3DSA:1.10.10.10 13 128 9.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41100 6ca99be729e6da908de9a7a96f6bb70c 196 SMART SM00418 14 107 2.7E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4R43_30070 82a23b7242656b2f0bda8e937f61af35 106 Pfam PF00037 4Fe-4S binding domain 34 56 8.1E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4R43_30070 82a23b7242656b2f0bda8e937f61af35 106 SUPERFAMILY SSF54862 1 70 5.73E-18 T 14-10-2018 A4R43_30070 82a23b7242656b2f0bda8e937f61af35 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.6E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4R43_30070 82a23b7242656b2f0bda8e937f61af35 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.6E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4R43_30070 82a23b7242656b2f0bda8e937f61af35 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.6E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4R43_30070 82a23b7242656b2f0bda8e937f61af35 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4R43_30070 82a23b7242656b2f0bda8e937f61af35 106 Gene3D G3DSA:3.30.70.20 2 106 1.3E-38 T 14-10-2018 A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 303 325 4.5E-23 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 360 374 4.5E-23 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 141 160 4.5E-23 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 375 389 4.5E-23 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 263 484 2.3E-45 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 292 469 8.6E-37 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 SUPERFAMILY SSF56601 115 491 1.34E-53 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 Gene3D G3DSA:3.40.710.10 280 487 7.0E-54 T 14-10-2018 A4R43_26860 525a7baa4e243be320b2de81faf3d069 494 Gene3D G3DSA:3.40.710.10 100 173 3.0E-10 T 14-10-2018 A4R43_25960 03ddb233c1d448c995838a235c885d30 138 Pfam PF03259 Roadblock/LC7 domain 11 100 1.0E-21 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_25960 03ddb233c1d448c995838a235c885d30 138 SUPERFAMILY SSF103196 3 127 2.62E-32 T 14-10-2018 A4R43_25960 03ddb233c1d448c995838a235c885d30 138 SMART SM00960 10 100 1.1E-31 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_25960 03ddb233c1d448c995838a235c885d30 138 Gene3D G3DSA:3.30.450.30 7 131 2.2E-41 T 14-10-2018 A4R43_40015 49aba7ee6fe4125e093b1200e2d6c5b1 436 Pfam PF07690 Major Facilitator Superfamily 26 392 2.3E-55 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_40015 49aba7ee6fe4125e093b1200e2d6c5b1 436 Gene3D G3DSA:1.20.1250.20 236 433 3.2E-28 T 14-10-2018 A4R43_40015 49aba7ee6fe4125e093b1200e2d6c5b1 436 PIRSF PIRSF002808 3 435 4.5E-37 T 14-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 A4R43_40015 49aba7ee6fe4125e093b1200e2d6c5b1 436 SUPERFAMILY SSF103473 15 429 2.62E-78 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_40015 49aba7ee6fe4125e093b1200e2d6c5b1 436 Gene3D G3DSA:1.20.1250.20 11 206 8.8E-49 T 14-10-2018 A4R43_34725 22f40ec0928085371adf0655c8bd5083 335 Gene3D G3DSA:2.115.10.20 154 279 1.1E-10 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_34725 22f40ec0928085371adf0655c8bd5083 335 SUPERFAMILY SSF75005 80 266 1.74E-21 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_34725 22f40ec0928085371adf0655c8bd5083 335 Gene3D G3DSA:2.115.10.20 61 153 3.8E-11 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A4R43_06465 e3d6181242a73fa517034b4502426021 414 Gene3D G3DSA:3.40.190.10 39 340 3.7E-65 T 14-10-2018 A4R43_06465 e3d6181242a73fa517034b4502426021 414 Pfam PF13416 Bacterial extracellular solute-binding protein 36 344 1.4E-31 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_06465 e3d6181242a73fa517034b4502426021 414 Gene3D G3DSA:3.40.190.10 134 400 3.7E-65 T 14-10-2018 A4R43_06465 e3d6181242a73fa517034b4502426021 414 SUPERFAMILY SSF53850 19 412 6.21E-44 T 14-10-2018 A4R43_37210 7c9ccd43619bad47da8e9d6fc99ba903 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 522 6.8E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_37210 7c9ccd43619bad47da8e9d6fc99ba903 547 Gene3D G3DSA:3.40.50.12780 6 431 1.4E-123 T 14-10-2018 A4R43_37210 7c9ccd43619bad47da8e9d6fc99ba903 547 SUPERFAMILY SSF56801 19 534 1.02E-159 T 14-10-2018 A4R43_37210 7c9ccd43619bad47da8e9d6fc99ba903 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_37210 7c9ccd43619bad47da8e9d6fc99ba903 547 Pfam PF00501 AMP-binding enzyme 25 437 1.0E-112 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_37210 7c9ccd43619bad47da8e9d6fc99ba903 547 Gene3D G3DSA:3.30.300.30 432 535 7.8E-31 T 14-10-2018 A4R43_15345 7c07a39e7dabc169e1fe5ca1540fb02a 237 Gene3D G3DSA:2.60.120.620 24 233 2.9E-7 T 14-10-2018 A4R43_15345 7c07a39e7dabc169e1fe5ca1540fb02a 237 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 65 236 1.2E-78 T 14-10-2018 IPR018655 Protein of unknown function DUF2086 A4R43_09165 6afdd306f0edfd73993cbdf116ceee2a 349 SUPERFAMILY SSF56726 187 261 3.92E-5 T 14-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A4R43_09165 6afdd306f0edfd73993cbdf116ceee2a 349 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 192 258 6.0E-7 T 14-10-2018 IPR024534 Domain of unknown function DUF2220 A4R43_17050 414a22d419d84b6a95b1adb9c59c77b4 227 Pfam PF03591 AzlC protein 22 151 2.8E-24 T 14-10-2018 IPR011606 Branched-chain amino acid transport, permease A4R43_34610 680f71cf3be6dd3eec525a6fdd5703a8 268 Gene3D G3DSA:3.60.10.10 1 267 4.4E-71 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_34610 680f71cf3be6dd3eec525a6fdd5703a8 268 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 256 4.9E-13 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4R43_34610 680f71cf3be6dd3eec525a6fdd5703a8 268 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 5 262 6.7E-67 T 14-10-2018 A4R43_34610 680f71cf3be6dd3eec525a6fdd5703a8 268 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 263 5.7E-69 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A4R43_34610 680f71cf3be6dd3eec525a6fdd5703a8 268 SUPERFAMILY SSF56219 2 264 3.93E-68 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_40145 835292f08075a17d5b89bae9488fe008 269 SUPERFAMILY SSF51621 6 217 1.36E-54 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_40145 835292f08075a17d5b89bae9488fe008 269 Gene3D G3DSA:3.20.20.60 3 268 3.6E-77 T 14-10-2018 A4R43_40145 835292f08075a17d5b89bae9488fe008 269 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 7 205 8.9E-30 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_40145 835292f08075a17d5b89bae9488fe008 269 PIRSF PIRSF015582 4 269 5.3E-69 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like A4R43_29955 762a78a086431be5b5de210675371423 126 SUPERFAMILY SSF54637 1 100 2.55E-21 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_29955 762a78a086431be5b5de210675371423 126 Pfam PF03061 Thioesterase superfamily 15 66 5.8E-9 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4R43_29955 762a78a086431be5b5de210675371423 126 Gene3D G3DSA:3.10.129.10 1 104 3.2E-23 T 14-10-2018 A4R43_41425 844f2e4dd5192aef25d82c1d15422b25 346 Gene3D G3DSA:3.20.20.140 1 345 3.7E-145 T 14-10-2018 A4R43_41425 844f2e4dd5192aef25d82c1d15422b25 346 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 11 333 1.0E-113 T 14-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A4R43_41425 844f2e4dd5192aef25d82c1d15422b25 346 SUPERFAMILY SSF51556 4 337 3.4E-106 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_28855 832bd51ad07be93b75b7ef973b8a24dd 273 Gene3D G3DSA:2.80.10.50 134 271 1.1E-9 T 14-10-2018 A4R43_28855 832bd51ad07be93b75b7ef973b8a24dd 273 SUPERFAMILY SSF50370 135 270 1.11E-11 T 14-10-2018 IPR035992 Ricin B-like lectins A4R43_15290 8bd05baad82542eb67013a4c5d227db3 298 PRINTS PR00075 Fatty acid desaturase family 1 signature 38 60 7.7E-17 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_15290 8bd05baad82542eb67013a4c5d227db3 298 PRINTS PR00075 Fatty acid desaturase family 1 signature 241 255 7.7E-17 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_15290 8bd05baad82542eb67013a4c5d227db3 298 PRINTS PR00075 Fatty acid desaturase family 1 signature 61 81 7.7E-17 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_15290 8bd05baad82542eb67013a4c5d227db3 298 PRINTS PR00075 Fatty acid desaturase family 1 signature 198 219 7.7E-17 T 14-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4R43_15290 8bd05baad82542eb67013a4c5d227db3 298 Pfam PF00487 Fatty acid desaturase 44 253 9.5E-19 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_33945 e9a8b470ef9c7d835c991c229f49ec59 206 Pfam PF01810 LysE type translocator 14 202 1.5E-23 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_33945 e9a8b470ef9c7d835c991c229f49ec59 206 PIRSF PIRSF006324 1 206 6.6E-46 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_41455 4ab1d26ebbe0dc5ff6033d070a5aa245 242 SUPERFAMILY SSF56784 8 241 8.86E-36 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_41455 4ab1d26ebbe0dc5ff6033d070a5aa245 242 Gene3D G3DSA:1.10.150.240 20 112 4.7E-49 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_41455 4ab1d26ebbe0dc5ff6033d070a5aa245 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 206 1.2E-14 T 14-10-2018 A4R43_41455 4ab1d26ebbe0dc5ff6033d070a5aa245 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 212 5.6E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4R43_41455 4ab1d26ebbe0dc5ff6033d070a5aa245 242 Gene3D G3DSA:3.40.50.1000 12 239 4.7E-49 T 14-10-2018 IPR023214 HAD superfamily A4R43_14490 7bc5a5202fd28aa80d5d58c4f0f5c817 225 SUPERFAMILY SSF56281 26 221 6.36E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_14490 7bc5a5202fd28aa80d5d58c4f0f5c817 225 Pfam PF00753 Metallo-beta-lactamase superfamily 34 190 4.4E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_14490 7bc5a5202fd28aa80d5d58c4f0f5c817 225 SMART SM00849 36 204 3.6E-28 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_14490 7bc5a5202fd28aa80d5d58c4f0f5c817 225 Gene3D G3DSA:3.60.15.10 24 222 2.9E-47 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_03320 e7f783ed926046d6126519c8526db53e 147 Gene3D G3DSA:3.10.450.50 2 145 2.1E-43 T 14-10-2018 A4R43_03320 e7f783ed926046d6126519c8526db53e 147 SUPERFAMILY SSF54427 9 143 2.17E-40 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_03320 e7f783ed926046d6126519c8526db53e 147 Pfam PF07366 SnoaL-like polyketide cyclase 14 139 5.5E-37 T 14-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 A4R43_16745 ef98f822f7ccb4fddddd7a3faadccb14 304 Pfam PF04228 Putative neutral zinc metallopeptidase 104 296 5.1E-18 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative A4R43_15050 2758dee96845d1701d57a60b251c2a96 252 Pfam PF01048 Phosphorylase superfamily 3 182 9.9E-23 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4R43_15050 2758dee96845d1701d57a60b251c2a96 252 SUPERFAMILY SSF53167 2 182 8.12E-29 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A4R43_15050 2758dee96845d1701d57a60b251c2a96 252 Gene3D G3DSA:3.40.50.1580 1 196 2.3E-39 T 14-10-2018 A4R43_20650 21e4bcb9edf257b54146c5d007649266 196 SUPERFAMILY SSF46785 1 106 2.69E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20650 21e4bcb9edf257b54146c5d007649266 196 Gene3D G3DSA:1.10.10.10 1 87 9.0E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20650 21e4bcb9edf257b54146c5d007649266 196 Pfam PF12840 Helix-turn-helix domain 11 68 2.2E-13 T 14-10-2018 A4R43_24180 3936df42a2a4d7076b2918d8e05383e6 114 Pfam PF05610 Protein of unknown function (DUF779) 14 112 2.1E-48 T 14-10-2018 IPR008497 Protein of unknown function DUF779 A4R43_24180 3936df42a2a4d7076b2918d8e05383e6 114 PIRSF PIRSF009151 1 114 8.7E-59 T 14-10-2018 IPR008497 Protein of unknown function DUF779 A4R43_03185 7b1a9d4213959d657f821e38b24004be 334 SUPERFAMILY SSF51430 36 289 2.62E-46 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_03185 7b1a9d4213959d657f821e38b24004be 334 Pfam PF00248 Aldo/keto reductase family 41 288 3.5E-30 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_03185 7b1a9d4213959d657f821e38b24004be 334 Gene3D G3DSA:3.20.20.100 24 287 1.5E-41 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_02730 f6d0d726065f8a831c1ad7caf54b8bb1 150 SUPERFAMILY SSF46785 11 110 1.18E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02730 f6d0d726065f8a831c1ad7caf54b8bb1 150 Pfam PF12802 MarR family 19 78 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_02730 f6d0d726065f8a831c1ad7caf54b8bb1 150 Gene3D G3DSA:1.10.10.10 2 84 2.2E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15270 13695709a0aad6624f30107910318ad0 341 Pfam PF13814 Replication-relaxation 37 225 1.4E-47 T 14-10-2018 IPR025855 Plasmid replication-relaxation A4R43_01965 7fe946a791fc8c90089f8b6e20f0058a 150 Pfam PF14016 Protein of unknown function (DUF4232) 9 137 7.3E-25 T 14-10-2018 IPR025326 Protein of unknown function DUF4232 A4R43_40710 302fef906d8ce878502c6abea1e33594 368 SUPERFAMILY SSF53756 26 284 4.87E-8 T 14-10-2018 A4R43_14140 f5b6d54ba52e7c7e72be59f1eebf7a9f 231 SUPERFAMILY SSF69593 20 213 3.53E-32 T 14-10-2018 A4R43_14140 f5b6d54ba52e7c7e72be59f1eebf7a9f 231 Pfam PF01553 Acyltransferase 37 147 6.9E-19 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_14140 f5b6d54ba52e7c7e72be59f1eebf7a9f 231 SMART SM00563 52 162 4.5E-22 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_04670 86d4ebfebc6fa1af6d6128d82e704c41 143 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 143 61.951 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_04670 86d4ebfebc6fa1af6d6128d82e704c41 143 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 3 140 2.0E-39 T 14-10-2018 A4R43_04670 86d4ebfebc6fa1af6d6128d82e704c41 143 Gene3D G3DSA:3.40.50.9100 1 143 8.2E-58 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_04670 86d4ebfebc6fa1af6d6128d82e704c41 143 SUPERFAMILY SSF52304 2 141 5.23E-55 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_04670 86d4ebfebc6fa1af6d6128d82e704c41 143 PIRSF PIRSF001399 1 143 3.8E-57 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_04670 86d4ebfebc6fa1af6d6128d82e704c41 143 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 2 140 6.9E-56 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_04670 86d4ebfebc6fa1af6d6128d82e704c41 143 Pfam PF01220 Dehydroquinase class II 2 138 5.4E-54 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4R43_15375 95ec7b6f37e795777373727cc6af305a 108 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 91 6.9E-28 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A4R43_15375 95ec7b6f37e795777373727cc6af305a 108 Pfam PF12823 Domain of unknown function (DUF3817) 7 93 1.6E-26 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A4R43_34070 efb10734d9fe6581deeaffe63dba0c80 94 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 88 2.6E-22 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_34070 efb10734d9fe6581deeaffe63dba0c80 94 Gene3D G3DSA:1.10.287.1060 2 94 1.4E-23 T 14-10-2018 A4R43_34070 efb10734d9fe6581deeaffe63dba0c80 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 2.4E-18 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_34070 efb10734d9fe6581deeaffe63dba0c80 94 SUPERFAMILY SSF140453 3 93 8.89E-23 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_07465 47b0ed211e09f03c974533bc691cbeb5 156 Pfam PF14325 Domain of unknown function (DUF4383) 24 147 1.4E-43 T 14-10-2018 IPR025492 Protein of unknown function DUF4383 A4R43_10740 4a80f1bb72c9dfa062390ee958331cf7 322 Pfam PF13280 WYL domain 147 311 1.1E-30 T 14-10-2018 IPR026881 WYL domain A4R43_10740 4a80f1bb72c9dfa062390ee958331cf7 322 PIRSF PIRSF016838 1 322 1.1E-116 T 14-10-2018 IPR028349 Protein PafC A4R43_35200 c2fa281ad0d860ea068e01f7376f3713 266 Pfam PF10974 Protein of unknown function (DUF2804) 109 263 4.1E-24 T 14-10-2018 IPR021243 Protein of unknown function DUF2804 A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 Pfam PF00106 short chain dehydrogenase 5 193 3.0E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.6E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.6E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.6E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.6E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.3E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.3E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.3E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 Gene3D G3DSA:3.40.50.720 2 241 7.7E-66 T 14-10-2018 A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 SUPERFAMILY SSF51735 2 229 4.6E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_08585 7f83ec2b445e8bc99355c66af91d735d 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_05965 dfb2701fd71e4cda61e3b92dcc81756a 208 SUPERFAMILY SSF46689 2 52 5.99E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_05965 dfb2701fd71e4cda61e3b92dcc81756a 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 4 34 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_05965 dfb2701fd71e4cda61e3b92dcc81756a 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 38 1.7E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_05965 dfb2701fd71e4cda61e3b92dcc81756a 208 Gene3D G3DSA:1.10.357.10 1 147 1.1E-16 T 14-10-2018 A4R43_28960 a556004d1c331b8265281acd4cf0dd62 216 Gene3D G3DSA:3.40.50.720 2 216 6.9E-47 T 14-10-2018 A4R43_28960 a556004d1c331b8265281acd4cf0dd62 216 Pfam PF13460 NAD(P)H-binding 7 192 3.4E-42 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_28960 a556004d1c331b8265281acd4cf0dd62 216 SUPERFAMILY SSF51735 1 204 1.17E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_08285 3ee64d1aef874bb5fc21e92c53f21623 477 SUPERFAMILY SSF103473 19 469 7.06E-44 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08285 3ee64d1aef874bb5fc21e92c53f21623 477 Pfam PF07690 Major Facilitator Superfamily 23 357 1.0E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_08285 3ee64d1aef874bb5fc21e92c53f21623 477 Gene3D G3DSA:1.20.1250.20 266 475 8.3E-15 T 14-10-2018 A4R43_08285 3ee64d1aef874bb5fc21e92c53f21623 477 Gene3D G3DSA:1.20.1250.20 14 206 2.6E-24 T 14-10-2018 A4R43_05695 4a1062060ad367b5fdd5a9cbf4982630 141 Gene3D G3DSA:3.30.530.20 2 141 6.9E-32 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_05695 4a1062060ad367b5fdd5a9cbf4982630 141 SUPERFAMILY SSF55961 6 139 3.67E-28 T 14-10-2018 A4R43_05695 4a1062060ad367b5fdd5a9cbf4982630 141 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 137 3.0E-11 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A4R43_08570 f2ae90ee5899a99aff98ab201caa161b 129 Pfam PF00089 Trypsin 6 124 1.2E-14 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4R43_08570 f2ae90ee5899a99aff98ab201caa161b 129 SUPERFAMILY SSF50494 6 129 3.25E-21 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_08570 f2ae90ee5899a99aff98ab201caa161b 129 Gene3D G3DSA:2.40.10.10 2 129 2.5E-18 T 14-10-2018 A4R43_22615 e71c368f69eeb6e15aca89f5d87a06a8 256 Gene3D G3DSA:3.40.50.720 3 256 3.0E-52 T 14-10-2018 A4R43_22615 e71c368f69eeb6e15aca89f5d87a06a8 256 SUPERFAMILY SSF51735 2 210 6.78E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_22615 e71c368f69eeb6e15aca89f5d87a06a8 256 Pfam PF13460 NAD(P)H-binding 70 166 4.6E-8 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_04450 68d235780cab1f872a20ecd59b129805 217 Pfam PF07978 NIPSNAP 6 102 3.9E-18 T 14-10-2018 IPR012577 NIPSNAP A4R43_04450 68d235780cab1f872a20ecd59b129805 217 Gene3D G3DSA:3.30.70.100 2 104 2.8E-15 T 14-10-2018 A4R43_04450 68d235780cab1f872a20ecd59b129805 217 SUPERFAMILY SSF54909 5 101 7.84E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_11470 d99ce020881fa1bc18f65fd5cba5f5ec 336 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 8 305 1.1E-20 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A4R43_11470 d99ce020881fa1bc18f65fd5cba5f5ec 336 Gene3D G3DSA:3.30.420.40 5 304 2.7E-56 T 14-10-2018 A4R43_11470 d99ce020881fa1bc18f65fd5cba5f5ec 336 Gene3D G3DSA:3.30.420.40 117 293 2.7E-56 T 14-10-2018 A4R43_11470 d99ce020881fa1bc18f65fd5cba5f5ec 336 SUPERFAMILY SSF53067 119 312 3.46E-32 T 14-10-2018 A4R43_11470 d99ce020881fa1bc18f65fd5cba5f5ec 336 SUPERFAMILY SSF53067 1 115 1.4E-14 T 14-10-2018 A4R43_00710 3d3b1f2f015c18885bda17316150d19a 430 SUPERFAMILY SSF103473 14 425 6.8E-60 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_00710 3d3b1f2f015c18885bda17316150d19a 430 Pfam PF00083 Sugar (and other) transporter 19 218 7.6E-20 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_00710 3d3b1f2f015c18885bda17316150d19a 430 Pfam PF00083 Sugar (and other) transporter 271 416 8.8E-7 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4R43_00710 3d3b1f2f015c18885bda17316150d19a 430 Gene3D G3DSA:1.20.1250.20 15 429 5.7E-58 T 14-10-2018 A4R43_38590 5cb92d9edab5187ff27d582c25e82ebc 348 Pfam PF00296 Luciferase-like monooxygenase 4 311 2.4E-42 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_38590 5cb92d9edab5187ff27d582c25e82ebc 348 TIGRFAM TIGR04020 seco_metab_LLM: natural product biosynthesis luciferase-like monooxygenase domain 5 336 2.4E-137 T 14-10-2018 IPR024011 Natural product biosynthesis luciferase-like monooxygenase domain A4R43_38590 5cb92d9edab5187ff27d582c25e82ebc 348 SUPERFAMILY SSF51679 3 332 4.06E-68 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_38590 5cb92d9edab5187ff27d582c25e82ebc 348 Gene3D G3DSA:3.20.20.30 3 335 1.2E-89 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_41525 e99bdfd21b6c7f237bc17932817c38a3 555 Gene3D G3DSA:3.75.10.10 210 553 1.3E-86 T 14-10-2018 A4R43_41525 e99bdfd21b6c7f237bc17932817c38a3 555 Pfam PF03068 Protein-arginine deiminase (PAD) 167 550 3.0E-68 T 14-10-2018 IPR013530 Protein-arginine deiminase, C-terminal GO:0004668|GO:0005509|GO:0005737 MetaCyc: PWY-4921|Reactome: R-HSA-3247509 A4R43_41525 e99bdfd21b6c7f237bc17932817c38a3 555 SUPERFAMILY SSF55909 234 551 8.04E-53 T 14-10-2018 A4R43_30880 bf2d68c0fb9b0ca99e97c12550e1e570 441 SUPERFAMILY SSF103473 10 439 4.84E-88 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_30880 bf2d68c0fb9b0ca99e97c12550e1e570 441 Pfam PF07690 Major Facilitator Superfamily 24 394 1.3E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_30880 bf2d68c0fb9b0ca99e97c12550e1e570 441 Gene3D G3DSA:1.20.1250.20 8 439 2.4E-84 T 14-10-2018 A4R43_18695 815319a6de3b84548e1dcfcc41b0d003 174 Pfam PF02669 K+-transporting ATPase, c chain 1 169 3.6E-48 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A4R43_18695 815319a6de3b84548e1dcfcc41b0d003 174 PIRSF PIRSF001296 1 174 2.6E-44 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A4R43_13740 928314bbc912b967deb1c897be8d54f9 256 SUPERFAMILY SSF56219 16 256 7.98E-32 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_13740 928314bbc912b967deb1c897be8d54f9 256 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 24 246 1.0E-14 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4R43_13740 928314bbc912b967deb1c897be8d54f9 256 Gene3D G3DSA:3.60.10.10 20 256 5.8E-54 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4R43_18300 79d5bdc5675c2e5b92ccf8ec0832add5 589 Pfam PF00905 Penicillin binding protein transpeptidase domain 318 580 9.2E-41 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4R43_18300 79d5bdc5675c2e5b92ccf8ec0832add5 589 Gene3D G3DSA:3.40.710.10 297 587 1.2E-56 T 14-10-2018 A4R43_18300 79d5bdc5675c2e5b92ccf8ec0832add5 589 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 30 135 5.6E-12 T 14-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 A4R43_18300 79d5bdc5675c2e5b92ccf8ec0832add5 589 SUPERFAMILY SSF56601 298 585 1.59E-55 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_00300 d7ace69eefbb31b7f8bc625d25ef7c6a 160 SUPERFAMILY SSF54427 2 141 3.93E-34 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_00300 d7ace69eefbb31b7f8bc625d25ef7c6a 160 Gene3D G3DSA:3.10.450.50 1 156 1.6E-40 T 14-10-2018 A4R43_00300 d7ace69eefbb31b7f8bc625d25ef7c6a 160 Pfam PF13577 SnoaL-like domain 3 128 1.2E-29 T 14-10-2018 IPR037401 SnoaL-like domain A4R43_02460 6dd16e3851c362e42ded042efebebcfc 255 SMART SM01007 8 224 1.6E-23 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_02460 6dd16e3851c362e42ded042efebebcfc 255 Gene3D G3DSA:3.40.225.10 1 226 2.1E-35 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_02460 6dd16e3851c362e42ded042efebebcfc 255 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 223 1.4E-25 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4R43_02460 6dd16e3851c362e42ded042efebebcfc 255 SUPERFAMILY SSF53639 2 225 1.02E-29 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4R43_16635 935f801e617f636dab0d9098b7519b34 284 Pfam PF02405 Permease MlaE 67 271 1.5E-59 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_04005 00e422358e17f9fce2847a33a51ae27f 297 Gene3D G3DSA:3.40.50.1820 52 293 1.3E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_04005 00e422358e17f9fce2847a33a51ae27f 297 SUPERFAMILY SSF53474 29 294 1.0E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_04005 00e422358e17f9fce2847a33a51ae27f 297 Pfam PF12697 Alpha/beta hydrolase family 60 280 5.8E-15 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_10800 79180b6b0d4bd2a451c1c4b393429b6e 312 Pfam PF00248 Aldo/keto reductase family 40 290 1.5E-17 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_10800 79180b6b0d4bd2a451c1c4b393429b6e 312 SUPERFAMILY SSF51430 39 295 2.23E-31 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_10800 79180b6b0d4bd2a451c1c4b393429b6e 312 Gene3D G3DSA:3.20.20.100 2 286 1.6E-34 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_20325 056091046f3aa429d01c6ac3a5a95b64 185 SUPERFAMILY SSF48498 81 184 2.97E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_20325 056091046f3aa429d01c6ac3a5a95b64 185 SUPERFAMILY SSF46689 2 74 3.74E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_20325 056091046f3aa429d01c6ac3a5a95b64 185 Gene3D G3DSA:1.10.357.10 3 185 2.7E-40 T 14-10-2018 A4R43_20325 056091046f3aa429d01c6ac3a5a95b64 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 1.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_20325 056091046f3aa429d01c6ac3a5a95b64 185 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 184 2.3E-9 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_31020 a853100d878be05115a008ef664458dd 538 Pfam PF00561 alpha/beta hydrolase fold 108 281 2.1E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_31020 a853100d878be05115a008ef664458dd 538 SUPERFAMILY SSF53474 98 500 7.32E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_31020 a853100d878be05115a008ef664458dd 538 Pfam PF08386 TAP-like protein 430 524 5.7E-19 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_30185 9ae4b43f7ca65ea92cce78025994a7d7 331 ProSitePatterns PS01007 Transposases, Mutator family, signature. 158 182 - T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4R43_30185 9ae4b43f7ca65ea92cce78025994a7d7 331 Pfam PF00872 Transposase, Mutator family 109 300 9.6E-61 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4R43_30185 9ae4b43f7ca65ea92cce78025994a7d7 331 Pfam PF00872 Transposase, Mutator family 18 101 9.5E-19 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4R43_32075 7141ca221e1759a96be8db46ad1399fb 143 Gene3D G3DSA:3.40.30.10 24 140 1.3E-11 T 14-10-2018 A4R43_32075 7141ca221e1759a96be8db46ad1399fb 143 SUPERFAMILY SSF52833 30 140 4.23E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_32075 7141ca221e1759a96be8db46ad1399fb 143 Pfam PF00085 Thioredoxin 54 125 1.1E-6 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 A4R43_03410 24ffdc607dc92fc62a24f49f68b5f5ac 658 Gene3D G3DSA:1.20.1740.10 56 504 8.9E-10 T 14-10-2018 A4R43_41085 45123a9d47300c8b4904d3531d2702f9 342 SUPERFAMILY SSF53335 135 299 1.7E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_41085 45123a9d47300c8b4904d3531d2702f9 342 Pfam PF01170 Putative RNA methylase family UPF0020 135 262 9.1E-5 T 14-10-2018 IPR000241 Putative RNA methylase domain A4R43_25010 98b09ca0ca382d35b2606f9c73d95b2c 217 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 42 166 2.6E-30 T 14-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated A4R43_25010 98b09ca0ca382d35b2606f9c73d95b2c 217 SUPERFAMILY SSF53448 8 204 7.31E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_25010 98b09ca0ca382d35b2606f9c73d95b2c 217 Gene3D G3DSA:3.90.550.10 3 213 1.6E-52 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.496 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 3.2E-67 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 PIRSF PIRSF002133 1 124 2.3E-54 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 3.0E-43 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 Gene3D G3DSA:2.40.50.140 1 124 5.6E-63 T 14-10-2018 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.3E-58 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.3E-58 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.3E-58 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.3E-58 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.3E-58 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.3E-58 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33815 ae29109f2b576bfb7d58bbbf9de7a324 124 SUPERFAMILY SSF50249 2 123 3.86E-52 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4R43_19270 27521e749fc446561abbfcb3fd5aef14 289 Gene3D G3DSA:3.30.530.20 1 159 4.9E-47 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_19270 27521e749fc446561abbfcb3fd5aef14 289 SUPERFAMILY SSF55961 2 146 2.04E-35 T 14-10-2018 A4R43_19270 27521e749fc446561abbfcb3fd5aef14 289 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 146 2.7E-22 T 14-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G A4R43_34915 b707005d7f6c01bab14ba56c4c56ef45 229 Pfam PF07161 LppX_LprAFG lipoprotein 34 225 5.2E-51 T 14-10-2018 IPR009830 LppX/LprAFG lipoprotein family A4R43_34915 b707005d7f6c01bab14ba56c4c56ef45 229 Gene3D G3DSA:2.50.20.20 25 226 1.5E-60 T 14-10-2018 A4R43_34915 b707005d7f6c01bab14ba56c4c56ef45 229 SUPERFAMILY SSF89392 31 226 1.26E-40 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4R43_34915 b707005d7f6c01bab14ba56c4c56ef45 229 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 21 211 7.0E-21 T 14-10-2018 IPR009830 LppX/LprAFG lipoprotein family A4R43_41590 8fea4cb3ae5ebe7bb1458fee8949b92a 70 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 22 70 6.3E-14 T 14-10-2018 IPR012667 Cobalt transporter subunit CbtB, putative A4R43_16240 d0befd379e84807c28aeec29a708dfd7 380 Gene3D G3DSA:3.40.50.10540 7 326 9.1E-119 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_16240 d0befd379e84807c28aeec29a708dfd7 380 Pfam PF02515 CoA-transferase family III 8 351 3.9E-80 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_16240 d0befd379e84807c28aeec29a708dfd7 380 Gene3D G3DSA:3.30.1540.10 220 308 9.1E-119 T 14-10-2018 A4R43_16240 d0befd379e84807c28aeec29a708dfd7 380 SUPERFAMILY SSF89796 5 379 1.44E-115 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_28180 fb2dcae4e6710c5bf02a67ccafc88f40 295 Gene3D G3DSA:3.20.20.30 1 293 3.0E-60 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_28180 fb2dcae4e6710c5bf02a67ccafc88f40 295 Pfam PF00296 Luciferase-like monooxygenase 21 235 9.2E-46 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_28180 fb2dcae4e6710c5bf02a67ccafc88f40 295 SUPERFAMILY SSF51679 20 293 1.11E-51 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_26100 e5a17e6e6bb4d8140c64f5c9c680090a 233 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 23 232 35.044 T 14-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A4R43_26100 e5a17e6e6bb4d8140c64f5c9c680090a 233 Pfam PF02666 Phosphatidylserine decarboxylase 65 226 1.1E-27 T 14-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A4R43_26100 e5a17e6e6bb4d8140c64f5c9c680090a 233 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 42 230 3.8E-48 T 14-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A4R43_19550 37d7cd937d6083461515f67b4aeaa24a 161 Gene3D G3DSA:2.60.120.10 6 153 1.7E-22 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_19550 37d7cd937d6083461515f67b4aeaa24a 161 SUPERFAMILY SSF51182 15 148 1.34E-28 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_19550 37d7cd937d6083461515f67b4aeaa24a 161 Pfam PF05995 Cysteine dioxygenase type I 25 148 1.1E-22 T 14-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 A4R43_12725 50691eb84d85b75c720675d3db373769 267 SUPERFAMILY SSF52540 2 235 1.04E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_12725 50691eb84d85b75c720675d3db373769 267 Pfam PF00005 ABC transporter 20 170 3.0E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_12725 50691eb84d85b75c720675d3db373769 267 Gene3D G3DSA:3.40.50.300 1 259 1.4E-60 T 14-10-2018 A4R43_12725 50691eb84d85b75c720675d3db373769 267 SMART SM00382 29 251 3.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_08945 457257c9e8c3ab4d8d9c87e795029baf 645 SUPERFAMILY SSF53474 372 631 8.33E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08945 457257c9e8c3ab4d8d9c87e795029baf 645 Gene3D G3DSA:3.40.50.1820 364 644 7.4E-77 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08945 457257c9e8c3ab4d8d9c87e795029baf 645 Pfam PF00326 Prolyl oligopeptidase family 425 632 3.6E-44 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_08945 457257c9e8c3ab4d8d9c87e795029baf 645 SUPERFAMILY SSF69322 86 397 2.22E-13 T 14-10-2018 A4R43_34360 2a703abaf0be130bf4c71deaf3debe95 842 Pfam PF12770 CHAT domain 601 824 1.5E-23 T 14-10-2018 IPR024983 CHAT domain A4R43_34360 2a703abaf0be130bf4c71deaf3debe95 842 Gene3D G3DSA:1.25.40.10 50 356 2.9E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_34360 2a703abaf0be130bf4c71deaf3debe95 842 SUPERFAMILY SSF48452 125 362 8.85E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_21375 09838563ccee71c84c8cda0bb093250b 242 Gene3D G3DSA:1.10.10.60 142 222 7.1E-12 T 14-10-2018 A4R43_21375 09838563ccee71c84c8cda0bb093250b 242 Pfam PF12833 Helix-turn-helix domain 149 219 6.1E-12 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_21375 09838563ccee71c84c8cda0bb093250b 242 SMART SM00342 146 219 8.2E-4 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_11600 c6f5ea67505b155424c7444455856dce 454 SUPERFAMILY SSF103473 13 453 1.15E-15 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_11600 c6f5ea67505b155424c7444455856dce 454 Gene3D G3DSA:1.20.1250.20 17 448 9.0E-11 T 14-10-2018 A4R43_25825 c1c3c45783682682fd90c195c1e8b96e 732 SUPERFAMILY SSF103473 302 692 3.4E-26 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_25825 c1c3c45783682682fd90c195c1e8b96e 732 Pfam PF07690 Major Facilitator Superfamily 310 658 5.5E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_25825 c1c3c45783682682fd90c195c1e8b96e 732 Gene3D G3DSA:1.20.1250.20 300 690 7.9E-18 T 14-10-2018 A4R43_21000 6d5fb072a6a3e61b8a8782a77295be95 138 SUPERFAMILY SSF103196 3 129 6.98E-38 T 14-10-2018 A4R43_21000 6d5fb072a6a3e61b8a8782a77295be95 138 SMART SM00960 10 100 6.4E-31 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_21000 6d5fb072a6a3e61b8a8782a77295be95 138 Pfam PF03259 Roadblock/LC7 domain 9 100 8.9E-26 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_21000 6d5fb072a6a3e61b8a8782a77295be95 138 Gene3D G3DSA:3.30.450.30 6 131 4.3E-42 T 14-10-2018 A4R43_02035 d66c1ea7885d6200d46503659ab39ccd 230 Gene3D G3DSA:1.10.10.10 8 74 8.8E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_02035 d66c1ea7885d6200d46503659ab39ccd 230 SMART SM00345 15 73 3.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02035 d66c1ea7885d6200d46503659ab39ccd 230 SMART SM00895 83 209 3.0E-22 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_02035 d66c1ea7885d6200d46503659ab39ccd 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 64 8.5E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4R43_02035 d66c1ea7885d6200d46503659ab39ccd 230 Pfam PF07729 FCD domain 83 208 6.2E-24 T 14-10-2018 IPR011711 GntR, C-terminal A4R43_02035 d66c1ea7885d6200d46503659ab39ccd 230 SUPERFAMILY SSF48008 79 211 1.28E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_02035 d66c1ea7885d6200d46503659ab39ccd 230 Gene3D G3DSA:1.20.120.530 77 214 6.8E-31 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4R43_02035 d66c1ea7885d6200d46503659ab39ccd 230 SUPERFAMILY SSF46785 9 77 2.09E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19195 fc35e09a6aa2e59d87df1a8458493406 271 Pfam PF04909 Amidohydrolase 54 269 3.0E-43 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_19195 fc35e09a6aa2e59d87df1a8458493406 271 Gene3D G3DSA:3.20.20.140 3 269 3.1E-65 T 14-10-2018 A4R43_19195 fc35e09a6aa2e59d87df1a8458493406 271 SUPERFAMILY SSF51556 5 269 2.66E-62 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_01105 fc4522425d08f5662d61b32ca3b8e5c8 376 Pfam PF06067 Domain of unknown function (DUF932) 125 336 1.6E-42 T 14-10-2018 IPR026325 Protein of unknown function DUF932 A4R43_01105 fc4522425d08f5662d61b32ca3b8e5c8 376 TIGRFAM TIGR03299 LGT_TIGR03299: phage/plasmid-like protein TIGR03299 16 369 5.0E-51 T 14-10-2018 IPR017686 Phage/plasmid-like protein A4R43_15650 8a63a972d532ae95d3d324ca2e54c2e8 191 Pfam PF03713 Domain of unknown function (DUF305) 45 185 8.6E-36 T 14-10-2018 IPR005183 Domain of unknown function DUF305 A4R43_15650 8a63a972d532ae95d3d324ca2e54c2e8 191 Gene3D G3DSA:1.20.1260.10 34 188 6.1E-42 T 14-10-2018 IPR012347 Ferritin-like A4R43_32180 d9f5d928a4c419eb882f341b0869c2b9 508 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 192 207 - T 14-10-2018 IPR019826 Carboxylesterase type B, active site A4R43_32180 d9f5d928a4c419eb882f341b0869c2b9 508 Gene3D G3DSA:3.40.50.1820 24 508 3.5E-142 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_32180 d9f5d928a4c419eb882f341b0869c2b9 508 SUPERFAMILY SSF53474 27 479 1.09E-116 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_32180 d9f5d928a4c419eb882f341b0869c2b9 508 Pfam PF00135 Carboxylesterase family 28 478 4.4E-112 T 14-10-2018 IPR002018 Carboxylesterase, type B A4R43_09840 f6e8cd7810351c943121f870ff17ac76 126 SUPERFAMILY SSF82607 6 85 3.92E-5 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_09840 f6e8cd7810351c943121f870ff17ac76 126 Pfam PF02575 YbaB/EbfC DNA-binding family 7 85 1.7E-9 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 Pfam PF00106 short chain dehydrogenase 26 213 1.5E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 SUPERFAMILY SSF51735 21 259 1.96E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 Gene3D G3DSA:3.40.50.720 18 290 1.7E-56 T 14-10-2018 A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 4.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 4.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 4.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 3.1E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 3.1E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 3.1E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 3.1E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 27 44 3.1E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_13080 c9b5ec4610295c3a20e3035428168fcc 296 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 26 201 9.7E-4 T 14-10-2018 A4R43_02510 bec77f10d3abffd7bef6a4048cf7b314 143 Pfam PF01047 MarR family 35 86 6.8E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_02510 bec77f10d3abffd7bef6a4048cf7b314 143 SUPERFAMILY SSF46785 8 138 4.06E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_02510 bec77f10d3abffd7bef6a4048cf7b314 143 SMART SM00347 28 127 8.6E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_02510 bec77f10d3abffd7bef6a4048cf7b314 143 Gene3D G3DSA:1.10.10.10 4 141 6.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11745 61565e41f7f3c7bf66f7924658902e30 509 SUPERFAMILY SSF75304 28 503 7.59E-118 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_11745 61565e41f7f3c7bf66f7924658902e30 509 Pfam PF01425 Amidase 52 487 1.3E-106 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_11745 61565e41f7f3c7bf66f7924658902e30 509 Gene3D G3DSA:3.90.1300.10 24 509 7.3E-163 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_32960 00ad0e92a452840694ad4654e2d5fd0c 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 189 5.2E-34 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_32960 00ad0e92a452840694ad4654e2d5fd0c 208 SUPERFAMILY SSF53254 2 192 7.49E-35 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_32960 00ad0e92a452840694ad4654e2d5fd0c 208 SMART SM00855 4 156 1.1E-14 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4R43_32960 00ad0e92a452840694ad4654e2d5fd0c 208 Gene3D G3DSA:3.40.50.1240 1 199 2.1E-28 T 14-10-2018 IPR029033 Histidine phosphatase superfamily A4R43_14065 ab2862d9b42432792cea01fdf17f02cf 102 Pfam PF13834 Domain of unknown function (DUF4193) 1 102 5.1E-43 T 14-10-2018 IPR025242 Protein of unknown function DUF4193 A4R43_30080 8966361211686a2ff444103429bc475e 327 Pfam PF00268 Ribonucleotide reductase, small chain 33 287 7.3E-18 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_30080 8966361211686a2ff444103429bc475e 327 SUPERFAMILY SSF47240 28 287 1.62E-47 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_30080 8966361211686a2ff444103429bc475e 327 Gene3D G3DSA:1.10.620.20 5 300 3.0E-103 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4R43_07745 944c9ac4cfc79d2014b91a226a8e36d5 195 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 49 187 5.0E-20 T 14-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase A4R43_28385 ae624dca25ec1bc1f950b52a8de0a62b 116 Gene3D G3DSA:3.30.2010.20 2 115 2.6E-41 T 14-10-2018 IPR038555 Zincin-like metallopeptidase superfamily A4R43_28385 ae624dca25ec1bc1f950b52a8de0a62b 116 Pfam PF06262 Zincin-like metallopeptidase 29 115 2.4E-32 T 14-10-2018 IPR010428 Zincin-like metallopeptidase A4R43_28385 ae624dca25ec1bc1f950b52a8de0a62b 116 SUPERFAMILY SSF55486 4 115 6.38E-38 T 14-10-2018 A4R43_19660 f03abc7c1e5852a7d81227c7d4ba6a46 718 Pfam PF03176 MMPL family 451 685 1.1E-35 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_19660 f03abc7c1e5852a7d81227c7d4ba6a46 718 Pfam PF03176 MMPL family 45 362 4.6E-60 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_19660 f03abc7c1e5852a7d81227c7d4ba6a46 718 Gene3D G3DSA:1.20.1640.10 179 336 2.1E-9 T 14-10-2018 A4R43_19660 f03abc7c1e5852a7d81227c7d4ba6a46 718 SUPERFAMILY SSF82866 457 685 1.44E-30 T 14-10-2018 A4R43_19660 f03abc7c1e5852a7d81227c7d4ba6a46 718 Gene3D G3DSA:1.20.1640.10 481 683 2.0E-7 T 14-10-2018 A4R43_19660 f03abc7c1e5852a7d81227c7d4ba6a46 718 Gene3D G3DSA:1.20.1640.10 337 387 2.1E-9 T 14-10-2018 A4R43_19660 f03abc7c1e5852a7d81227c7d4ba6a46 718 SUPERFAMILY SSF82866 125 332 3.79E-31 T 14-10-2018 A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 Gene3D G3DSA:3.40.50.1820 4 272 4.9E-66 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 1.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 1.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 SUPERFAMILY SSF53474 5 272 7.25E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 Pfam PF00561 alpha/beta hydrolase fold 15 124 4.0E-22 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 PRINTS PR00412 Epoxide hydrolase signature 97 110 3.7E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 PRINTS PR00412 Epoxide hydrolase signature 20 38 3.7E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_08545 c3e6e635cc4c3cf969c8fdabccf95fbc 275 PRINTS PR00412 Epoxide hydrolase signature 83 96 3.7E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_40980 bc97cd66ff4e3d517764cb016fdca556 285 Pfam PF13359 DDE superfamily endonuclease 131 278 1.5E-22 T 14-10-2018 IPR027806 Harbinger transposase-derived nuclease domain A4R43_07490 bf3edbbce9897397cb1eef54a0fc4b11 295 Pfam PF13641 Glycosyltransferase like family 2 5 211 6.2E-14 T 14-10-2018 A4R43_07490 bf3edbbce9897397cb1eef54a0fc4b11 295 SUPERFAMILY SSF53448 4 229 1.97E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_07490 bf3edbbce9897397cb1eef54a0fc4b11 295 Gene3D G3DSA:3.90.550.10 2 214 9.5E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_18480 8dc0e24d16f10da891185f7bda62ff7f 354 Gene3D G3DSA:3.20.20.140 47 316 2.8E-50 T 14-10-2018 A4R43_18480 8dc0e24d16f10da891185f7bda62ff7f 354 SUPERFAMILY SSF51556 45 315 2.19E-55 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_18480 8dc0e24d16f10da891185f7bda62ff7f 354 Pfam PF01979 Amidohydrolase family 41 340 1.2E-14 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_18480 8dc0e24d16f10da891185f7bda62ff7f 354 Gene3D G3DSA:2.30.40.10 37 352 2.8E-50 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_17840 90e117f13f825baa4cd4cfdbe1346540 355 SUPERFAMILY SSF56601 38 324 2.71E-17 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_17840 90e117f13f825baa4cd4cfdbe1346540 355 Gene3D G3DSA:3.40.710.10 32 333 2.8E-36 T 14-10-2018 A4R43_17840 90e117f13f825baa4cd4cfdbe1346540 355 Pfam PF13354 Beta-lactamase enzyme family 55 271 2.0E-13 T 14-10-2018 A4R43_13635 a79901ead92afef6885c058088d71d26 698 SUPERFAMILY SSF82171 25 386 4.45E-40 T 14-10-2018 A4R43_13635 a79901ead92afef6885c058088d71d26 698 SUPERFAMILY SSF53474 446 689 2.03E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13635 a79901ead92afef6885c058088d71d26 698 Pfam PF00326 Prolyl oligopeptidase family 490 691 5.1E-48 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4R43_13635 a79901ead92afef6885c058088d71d26 698 Gene3D G3DSA:3.40.50.1820 444 689 7.1E-66 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13635 a79901ead92afef6885c058088d71d26 698 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 108 392 1.2E-38 T 14-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 A4R43_13635 a79901ead92afef6885c058088d71d26 698 Gene3D G3DSA:2.140.10.30 10 434 8.2E-86 T 14-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily A4R43_26510 0af07b0fe427de7ab6f00b7d2f235c41 265 PRINTS PR01543 Arylamine N-acetyltransferase signature 50 73 3.4E-6 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4R43_26510 0af07b0fe427de7ab6f00b7d2f235c41 265 PRINTS PR01543 Arylamine N-acetyltransferase signature 74 96 3.4E-6 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4R43_26510 0af07b0fe427de7ab6f00b7d2f235c41 265 PRINTS PR01543 Arylamine N-acetyltransferase signature 26 49 3.4E-6 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4R43_26510 0af07b0fe427de7ab6f00b7d2f235c41 265 Gene3D G3DSA:2.40.128.150 90 181 1.1E-79 T 14-10-2018 A4R43_26510 0af07b0fe427de7ab6f00b7d2f235c41 265 Pfam PF00797 N-acetyltransferase 29 253 8.0E-52 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4R43_26510 0af07b0fe427de7ab6f00b7d2f235c41 265 Gene3D G3DSA:3.30.2140.10 10 247 1.1E-79 T 14-10-2018 A4R43_26510 0af07b0fe427de7ab6f00b7d2f235c41 265 SUPERFAMILY SSF54001 6 246 1.96E-63 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_17120 5beaaa8f29c53f4e9e52f5b4b1d83c0e 463 SUPERFAMILY SSF51569 5 462 6.37E-192 T 14-10-2018 A4R43_17120 5beaaa8f29c53f4e9e52f5b4b1d83c0e 463 Pfam PF01474 Class-II DAHP synthetase family 31 458 5.1E-187 T 14-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4R43_17120 5beaaa8f29c53f4e9e52f5b4b1d83c0e 463 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 27 462 1.1E-211 T 14-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4R43_17120 5beaaa8f29c53f4e9e52f5b4b1d83c0e 463 Gene3D G3DSA:3.20.20.70 222 463 9.7E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_17120 5beaaa8f29c53f4e9e52f5b4b1d83c0e 463 Gene3D G3DSA:3.20.20.70 57 221 5.9E-52 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_23065 dd76cd7ca45ec632e2d5a91bf9d6f7ec 297 SUPERFAMILY SSF53850 34 295 1.33E-41 T 14-10-2018 A4R43_23065 dd76cd7ca45ec632e2d5a91bf9d6f7ec 297 Gene3D G3DSA:3.40.190.10 36 295 3.8E-64 T 14-10-2018 A4R43_23065 dd76cd7ca45ec632e2d5a91bf9d6f7ec 297 Gene3D G3DSA:3.40.190.120 134 236 3.8E-64 T 14-10-2018 A4R43_23065 dd76cd7ca45ec632e2d5a91bf9d6f7ec 297 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 34 291 7.3E-37 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 A4R43_21910 59d734a913479d45d509a33d7afc3e48 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4R43_21910 59d734a913479d45d509a33d7afc3e48 68 Gene3D G3DSA:3.30.70.100 3 66 8.9E-20 T 14-10-2018 A4R43_21910 59d734a913479d45d509a33d7afc3e48 68 Pfam PF00403 Heavy-metal-associated domain 5 64 3.4E-14 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4R43_21910 59d734a913479d45d509a33d7afc3e48 68 SUPERFAMILY SSF55008 1 66 2.09E-18 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A4R43_23995 b2edbd2e1ace6b1d760e69b0abe46f6d 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 2.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_23995 b2edbd2e1ace6b1d760e69b0abe46f6d 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 2.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_23995 b2edbd2e1ace6b1d760e69b0abe46f6d 198 SUPERFAMILY SSF46689 3 76 5.82E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_23995 b2edbd2e1ace6b1d760e69b0abe46f6d 198 Gene3D G3DSA:1.10.357.10 1 191 4.2E-48 T 14-10-2018 A4R43_23995 b2edbd2e1ace6b1d760e69b0abe46f6d 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 52 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4R43_23995 b2edbd2e1ace6b1d760e69b0abe46f6d 198 SUPERFAMILY SSF48498 87 187 1.63E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_23995 b2edbd2e1ace6b1d760e69b0abe46f6d 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 1.9E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21050 44e5fce96f7606d2b93ed6081a590515 396 Pfam PF07690 Major Facilitator Superfamily 15 191 2.1E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_21050 44e5fce96f7606d2b93ed6081a590515 396 Pfam PF07690 Major Facilitator Superfamily 230 388 3.8E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_21050 44e5fce96f7606d2b93ed6081a590515 396 Gene3D G3DSA:1.20.1250.20 9 385 3.8E-24 T 14-10-2018 A4R43_21050 44e5fce96f7606d2b93ed6081a590515 396 SUPERFAMILY SSF103473 15 383 7.59E-27 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_03115 4e293e5837ae470d339ab90f02bf6fbb 132 Gene3D G3DSA:3.30.750.24 5 119 4.5E-26 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_03115 4e293e5837ae470d339ab90f02bf6fbb 132 Pfam PF01740 STAS domain 22 99 1.2E-9 T 14-10-2018 IPR002645 STAS domain A4R43_03115 4e293e5837ae470d339ab90f02bf6fbb 132 SUPERFAMILY SSF52091 9 116 5.49E-18 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_13600 fb171f6b6440ebafb7b446a122d3e8d2 428 Gene3D G3DSA:3.30.590.10 123 426 2.0E-67 T 14-10-2018 A4R43_13600 fb171f6b6440ebafb7b446a122d3e8d2 428 Pfam PF00120 Glutamine synthetase, catalytic domain 128 371 6.5E-51 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_13600 fb171f6b6440ebafb7b446a122d3e8d2 428 SMART SM01230 126 358 2.8E-52 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4R43_13600 fb171f6b6440ebafb7b446a122d3e8d2 428 SUPERFAMILY SSF55931 127 423 4.02E-59 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_15045 e34e299738e1326ccc64b8a3c1a48dff 241 Gene3D G3DSA:1.10.10.10 155 227 2.9E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_15045 e34e299738e1326ccc64b8a3c1a48dff 241 SUPERFAMILY SSF55811 7 154 2.98E-31 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_15045 e34e299738e1326ccc64b8a3c1a48dff 241 SUPERFAMILY SSF46785 158 229 1.5E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_15045 e34e299738e1326ccc64b8a3c1a48dff 241 Gene3D G3DSA:3.90.79.10 9 154 2.9E-42 T 14-10-2018 A4R43_15045 e34e299738e1326ccc64b8a3c1a48dff 241 Pfam PF00293 NUDIX domain 18 128 2.1E-17 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_23060 55d73a84dd6cdb44f1b2e05a97930cb6 173 SUPERFAMILY SSF55729 1 157 1.74E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_23060 55d73a84dd6cdb44f1b2e05a97930cb6 173 Gene3D G3DSA:3.40.630.30 1 173 3.7E-44 T 14-10-2018 A4R43_23060 55d73a84dd6cdb44f1b2e05a97930cb6 173 Pfam PF00583 Acetyltransferase (GNAT) family 48 129 7.5E-8 T 14-10-2018 IPR000182 GNAT domain A4R43_35630 71773ea7046ad5d0e1eb31b359078cab 78 Pfam PF11314 Protein of unknown function (DUF3117) 27 75 4.5E-28 T 14-10-2018 IPR021465 Protein of unknown function DUF3117 A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 Pfam PF00106 short chain dehydrogenase 8 194 5.6E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 SUPERFAMILY SSF51735 3 254 3.42E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.9E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.9E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.9E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 Gene3D G3DSA:3.40.50.720 1 262 2.8E-58 T 14-10-2018 A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4R43_31605 c2b9a1dc88553e5fa45bef02058ba740 294 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 182 1.2E-4 T 14-10-2018 A4R43_09895 555043913d1c864a681142a0d6dd63ba 315 SUPERFAMILY SSF81345 2 310 2.48E-60 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_09895 555043913d1c864a681142a0d6dd63ba 315 Pfam PF01032 FecCD transport family 5 310 4.2E-70 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_09895 555043913d1c864a681142a0d6dd63ba 315 Gene3D G3DSA:1.10.3470.10 1 314 5.3E-73 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_22785 2416ba2b6e83b130c7e97c6725c4f24d 237 PIRSF PIRSF015736 2 237 7.8E-57 T 14-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase A4R43_22785 2416ba2b6e83b130c7e97c6725c4f24d 237 Gene3D G3DSA:3.40.50.12500 1 234 1.4E-61 T 14-10-2018 A4R43_22785 2416ba2b6e83b130c7e97c6725c4f24d 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 51 214 7.5E-7 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4R43_17560 7153e3f5ebb7cdd49531a6b6f8d7b53f 344 Pfam PF02445 Quinolinate synthetase A protein 31 336 5.5E-108 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4R43_17560 7153e3f5ebb7cdd49531a6b6f8d7b53f 344 SUPERFAMILY SSF142754 28 337 2.09E-99 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4R43_17560 7153e3f5ebb7cdd49531a6b6f8d7b53f 344 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 29 337 2.2E-86 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4R43_17560 7153e3f5ebb7cdd49531a6b6f8d7b53f 344 Gene3D G3DSA:3.40.50.10800 31 318 8.5E-108 T 14-10-2018 A4R43_17560 7153e3f5ebb7cdd49531a6b6f8d7b53f 344 Gene3D G3DSA:3.40.50.10800 196 293 8.5E-108 T 14-10-2018 A4R43_17560 7153e3f5ebb7cdd49531a6b6f8d7b53f 344 Gene3D G3DSA:3.40.50.10800 111 336 8.5E-108 T 14-10-2018 A4R43_00455 bcc22c955bde43724532fdfcfd7f9824 135 SUPERFAMILY SSF55298 16 134 1.15E-25 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_00455 bcc22c955bde43724532fdfcfd7f9824 135 Gene3D G3DSA:3.30.1330.40 7 135 1.1E-29 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_00455 bcc22c955bde43724532fdfcfd7f9824 135 Pfam PF01042 Endoribonuclease L-PSP 26 133 6.5E-19 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4R43_07670 4bd24c2320e2154632aa773821f13b0b 524 Gene3D G3DSA:3.40.309.10 264 457 1.5E-145 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_07670 4bd24c2320e2154632aa773821f13b0b 524 Pfam PF00171 Aldehyde dehydrogenase family 33 488 2.7E-135 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_07670 4bd24c2320e2154632aa773821f13b0b 524 Gene3D G3DSA:3.40.605.10 32 486 1.5E-145 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_07670 4bd24c2320e2154632aa773821f13b0b 524 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_07670 4bd24c2320e2154632aa773821f13b0b 524 SUPERFAMILY SSF53720 27 489 1.07E-137 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_02095 288e034fbe9a0912bad6f2fd99d43758 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 2 77 2.5E-13 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4R43_02095 288e034fbe9a0912bad6f2fd99d43758 98 SUPERFAMILY SSF54909 2 96 1.9E-30 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_02095 288e034fbe9a0912bad6f2fd99d43758 98 Gene3D G3DSA:3.30.70.100 1 96 1.4E-39 T 14-10-2018 A4R43_19965 867525830adfc2b6821aba1c5f8f0a77 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19965 867525830adfc2b6821aba1c5f8f0a77 188 SUPERFAMILY SSF48498 83 187 6.47E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_19965 867525830adfc2b6821aba1c5f8f0a77 188 SUPERFAMILY SSF46689 5 84 8.48E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19965 867525830adfc2b6821aba1c5f8f0a77 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19965 867525830adfc2b6821aba1c5f8f0a77 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_19965 867525830adfc2b6821aba1c5f8f0a77 188 Gene3D G3DSA:1.10.357.10 1 188 4.1E-55 T 14-10-2018 A4R43_16375 2752a10c4a5a108ae6f97e28dad7c1b5 145 SUPERFAMILY SSF55961 1 145 5.16E-33 T 14-10-2018 A4R43_16375 2752a10c4a5a108ae6f97e28dad7c1b5 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 9.2E-17 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_16375 2752a10c4a5a108ae6f97e28dad7c1b5 145 Gene3D G3DSA:3.30.530.20 2 144 1.0E-39 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_35695 2455d96e5e55545a2832b7246ee8b5bf 127 Pfam PF13828 Domain of unknown function (DUF4190) 49 111 1.7E-16 T 14-10-2018 IPR025241 Domain of unknown function DUF4190 A4R43_06170 08ca8b00c4257610f5e7200fa72a4b0f 148 Pfam PF01047 MarR family 41 98 5.2E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06170 08ca8b00c4257610f5e7200fa72a4b0f 148 SMART SM00347 34 134 2.1E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_06170 08ca8b00c4257610f5e7200fa72a4b0f 148 SUPERFAMILY SSF46785 9 145 6.03E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_06170 08ca8b00c4257610f5e7200fa72a4b0f 148 Gene3D G3DSA:1.10.10.10 14 145 1.2E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08960 2eb775212166249c99d310a18ca5c75d 198 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 102 7.8E-10 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4R43_08960 2eb775212166249c99d310a18ca5c75d 198 SUPERFAMILY SSF50475 7 130 3.14E-12 T 14-10-2018 A4R43_08960 2eb775212166249c99d310a18ca5c75d 198 Gene3D G3DSA:2.30.110.10 2 132 2.9E-18 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_34910 0bf159afc415cc439d91b6bf0c5bd9ed 502 Gene3D G3DSA:1.20.1720.10 15 223 1.3E-44 T 14-10-2018 A4R43_34910 0bf159afc415cc439d91b6bf0c5bd9ed 502 Gene3D G3DSA:1.20.1250.20 269 496 8.4E-9 T 14-10-2018 A4R43_34910 0bf159afc415cc439d91b6bf0c5bd9ed 502 SUPERFAMILY SSF103473 4 496 1.31E-51 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_34910 0bf159afc415cc439d91b6bf0c5bd9ed 502 Pfam PF07690 Major Facilitator Superfamily 19 251 5.2E-30 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_19430 769cb14939cb42b5408684c51c9ea902 114 Pfam PF02656 Domain of unknown function (DUF202) 13 79 6.4E-16 T 14-10-2018 IPR003807 Domain of unknown function DUF202 A4R43_35590 3a4c73f29f0d472a25067546453b0645 388 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 251 6.1E-94 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A4R43_35590 3a4c73f29f0d472a25067546453b0645 388 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 262 371 1.0E-27 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A4R43_27000 44ffb989d48ce63b2369206a1ffe61e4 211 SMART SM00943 22 182 1.5E-7 T 14-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4R43_27000 44ffb989d48ce63b2369206a1ffe61e4 211 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 24 175 9.2E-9 T 14-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4R43_17770 26ffe647c061e52dc6f0990eac84fbd4 329 Gene3D G3DSA:3.20.20.100 1 324 1.2E-113 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_17770 26ffe647c061e52dc6f0990eac84fbd4 329 Pfam PF00248 Aldo/keto reductase family 15 315 1.2E-74 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_17770 26ffe647c061e52dc6f0990eac84fbd4 329 PRINTS PR00069 Aldo-keto reductase signature 106 124 2.0E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_17770 26ffe647c061e52dc6f0990eac84fbd4 329 PRINTS PR00069 Aldo-keto reductase signature 137 154 2.0E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_17770 26ffe647c061e52dc6f0990eac84fbd4 329 PRINTS PR00069 Aldo-keto reductase signature 40 64 2.0E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4R43_17770 26ffe647c061e52dc6f0990eac84fbd4 329 SUPERFAMILY SSF51430 1 316 1.44E-97 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_10075 a917064496559e1fd7b1537fb66f7170 192 SUPERFAMILY SSF48498 86 190 2.17E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_10075 a917064496559e1fd7b1537fb66f7170 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 2.6E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_10075 a917064496559e1fd7b1537fb66f7170 192 Gene3D G3DSA:1.10.357.10 2 192 3.0E-54 T 14-10-2018 A4R43_10075 a917064496559e1fd7b1537fb66f7170 192 SUPERFAMILY SSF46689 10 83 5.34E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_10075 a917064496559e1fd7b1537fb66f7170 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_10075 a917064496559e1fd7b1537fb66f7170 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40570 30e2c75276c2789baf010dffedbbdf81 203 Pfam PF13302 Acetyltransferase (GNAT) domain 42 146 2.3E-9 T 14-10-2018 IPR000182 GNAT domain A4R43_40570 30e2c75276c2789baf010dffedbbdf81 203 SUPERFAMILY SSF55729 13 170 8.58E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_40570 30e2c75276c2789baf010dffedbbdf81 203 Gene3D G3DSA:3.40.630.30 9 192 3.5E-22 T 14-10-2018 A4R43_36090 508141ba66e73a1c65a086672f91f7fe 312 Pfam PF03186 CobD/Cbib protein 9 288 1.9E-58 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4R43_36090 508141ba66e73a1c65a086672f91f7fe 312 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 310 65.983 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4R43_09215 08af6ef51520e01da04fd4e96748e763 130 Gene3D G3DSA:3.40.960.10 9 128 1.0E-33 T 14-10-2018 A4R43_09215 08af6ef51520e01da04fd4e96748e763 130 SUPERFAMILY SSF52980 1 120 3.27E-29 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4R43_09215 08af6ef51520e01da04fd4e96748e763 130 Pfam PF03852 DNA mismatch endonuclease Vsr 1 61 1.9E-11 T 14-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 A4R43_11050 e0eb2f75712b147a370568dc7ae264a8 217 SUPERFAMILY SSF52172 2 180 3.95E-35 T 14-10-2018 IPR011006 CheY-like superfamily A4R43_11050 e0eb2f75712b147a370568dc7ae264a8 217 Gene3D G3DSA:1.10.10.10 115 216 4.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_11050 e0eb2f75712b147a370568dc7ae264a8 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 215 1.1E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_11050 e0eb2f75712b147a370568dc7ae264a8 217 SMART SM00448 1 109 3.9E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_11050 e0eb2f75712b147a370568dc7ae264a8 217 Pfam PF00072 Response regulator receiver domain 3 109 1.2E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4R43_11050 e0eb2f75712b147a370568dc7ae264a8 217 SMART SM00862 143 215 6.8E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_11050 e0eb2f75712b147a370568dc7ae264a8 217 Gene3D G3DSA:3.40.50.2300 1 114 3.8E-31 T 14-10-2018 A4R43_25820 0c5ab8281bfd76beb468357953ad06b3 256 SUPERFAMILY SSF50969 45 207 2.59E-6 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A4R43_25820 0c5ab8281bfd76beb468357953ad06b3 256 Pfam PF05096 Glutamine cyclotransferase 14 251 7.5E-85 T 14-10-2018 IPR007788 Glutaminyl-peptide cyclotransferase GO:0016603|GO:0017186 MetaCyc: PWY-7942 A4R43_30590 d2c1bd7dbbc12f2f080a52d62ca7e620 112 SUPERFAMILY SSF140453 11 106 6.02E-5 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_30590 d2c1bd7dbbc12f2f080a52d62ca7e620 112 Gene3D G3DSA:1.10.287.1060 9 106 4.8E-9 T 14-10-2018 A4R43_12140 0995fc0bc60f1eec45895effdf1edfbd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.5E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12140 0995fc0bc60f1eec45895effdf1edfbd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.5E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12140 0995fc0bc60f1eec45895effdf1edfbd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.5E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12140 0995fc0bc60f1eec45895effdf1edfbd 219 Gene3D G3DSA:1.10.10.10 105 219 2.4E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_12140 0995fc0bc60f1eec45895effdf1edfbd 219 SMART SM00421 156 213 1.4E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12140 0995fc0bc60f1eec45895effdf1edfbd 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 8.0E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4R43_12140 0995fc0bc60f1eec45895effdf1edfbd 219 SUPERFAMILY SSF46894 143 219 8.5E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37640 33ddc23f16b903fecf8addfe3e004651 74 SUPERFAMILY SSF47336 4 74 5.5E-8 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_37640 33ddc23f16b903fecf8addfe3e004651 74 Gene3D G3DSA:1.10.1200.10 1 74 5.7E-6 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_16905 de0ed671c38247193ccd6b4b50f6378d 251 SUPERFAMILY SSF52540 10 244 3.1E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_16905 de0ed671c38247193ccd6b4b50f6378d 251 Pfam PF00005 ABC transporter 26 174 4.0E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_16905 de0ed671c38247193ccd6b4b50f6378d 251 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_16905 de0ed671c38247193ccd6b4b50f6378d 251 SMART SM00382 35 222 1.6E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_16905 de0ed671c38247193ccd6b4b50f6378d 251 Gene3D G3DSA:3.40.50.300 8 251 1.4E-78 T 14-10-2018 A4R43_16905 de0ed671c38247193ccd6b4b50f6378d 251 PIRSF PIRSF039085 7 250 3.1E-110 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4R43_13285 82e4c82a56870dd12f23e9964c6125fc 151 SUPERFAMILY SSF55729 1 150 8.86E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_13285 82e4c82a56870dd12f23e9964c6125fc 151 Gene3D G3DSA:3.40.630.30 1 151 1.6E-37 T 14-10-2018 A4R43_13285 82e4c82a56870dd12f23e9964c6125fc 151 Pfam PF00583 Acetyltransferase (GNAT) family 35 129 2.2E-11 T 14-10-2018 IPR000182 GNAT domain A4R43_34385 68df8b8d1507561017682978258fb6a9 422 Pfam PF04024 PspC domain 32 82 4.4E-11 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A4R43_34385 68df8b8d1507561017682978258fb6a9 422 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 329 419 2.8E-9 T 14-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF A4R43_09755 9fd1fb12f4ca2bc341779464f68cf7de 332 Pfam PF01497 Periplasmic binding protein 52 304 2.0E-37 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_09755 9fd1fb12f4ca2bc341779464f68cf7de 332 Gene3D G3DSA:3.40.50.1980 154 330 1.3E-54 T 14-10-2018 A4R43_09755 9fd1fb12f4ca2bc341779464f68cf7de 332 Gene3D G3DSA:3.40.50.1980 27 144 1.6E-33 T 14-10-2018 A4R43_09755 9fd1fb12f4ca2bc341779464f68cf7de 332 SUPERFAMILY SSF53807 47 326 2.71E-42 T 14-10-2018 A4R43_24115 e1e9518701d73172705fd5aed852605a 327 Pfam PF13810 Domain of unknown function (DUF4185) 20 322 5.2E-110 T 14-10-2018 IPR025442 Domain of unknown function DUF4185 A4R43_24115 e1e9518701d73172705fd5aed852605a 327 SUPERFAMILY SSF110296 23 196 1.28E-5 T 14-10-2018 A4R43_33760 fe8d45e64afcf6e483e4037af8b3b1e1 352 Gene3D G3DSA:3.40.50.2300 58 333 3.4E-74 T 14-10-2018 A4R43_33760 fe8d45e64afcf6e483e4037af8b3b1e1 352 SUPERFAMILY SSF53822 56 346 1.26E-55 T 14-10-2018 IPR028082 Periplasmic binding protein-like I A4R43_33760 fe8d45e64afcf6e483e4037af8b3b1e1 352 Pfam PF13407 Periplasmic binding protein domain 58 312 4.7E-40 T 14-10-2018 IPR025997 Periplasmic binding protein A4R43_33760 fe8d45e64afcf6e483e4037af8b3b1e1 352 Gene3D G3DSA:3.40.50.2300 160 345 3.4E-74 T 14-10-2018 A4R43_00445 d6953c1b505e3100ad86cc6e2cab6b71 243 Gene3D G3DSA:3.20.20.70 1 242 1.2E-67 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_00445 d6953c1b505e3100ad86cc6e2cab6b71 243 SUPERFAMILY SSF51351 1 234 5.24E-65 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_00445 d6953c1b505e3100ad86cc6e2cab6b71 243 Pfam PF00121 Triosephosphate isomerase 1 231 2.8E-58 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4R43_14590 41820fd8a867a1403b2310a85e8e210b 327 Gene3D G3DSA:3.40.50.1100 23 323 5.2E-100 T 14-10-2018 A4R43_14590 41820fd8a867a1403b2310a85e8e210b 327 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 31 318 6.7E-73 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4R43_14590 41820fd8a867a1403b2310a85e8e210b 327 SUPERFAMILY SSF53686 19 325 3.14E-84 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4R43_14590 41820fd8a867a1403b2310a85e8e210b 327 Gene3D G3DSA:3.40.50.1100 66 159 5.2E-100 T 14-10-2018 A4R43_06220 f2fbbf81d4e9de85341e2bd0b29f634b 132 Pfam PF14325 Domain of unknown function (DUF4383) 4 121 3.6E-26 T 14-10-2018 IPR025492 Protein of unknown function DUF4383 A4R43_22740 0dbfb8eab25e171010abf6dc4682680f 85 Gene3D G3DSA:1.10.10.1150 2 84 7.1E-26 T 14-10-2018 A4R43_22740 0dbfb8eab25e171010abf6dc4682680f 85 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 22 82 7.0E-12 T 14-10-2018 IPR008792 Coenzyme PQQ synthesis D A4R43_22740 0dbfb8eab25e171010abf6dc4682680f 85 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 5 82 1.3E-22 T 14-10-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 A4R43_22185 c38400eed9ce2b018c8cc9993e5e7006 386 SUPERFAMILY SSF63825 149 366 6.8E-11 T 14-10-2018 A4R43_22185 c38400eed9ce2b018c8cc9993e5e7006 386 Pfam PF05787 Bacterial protein of unknown function (DUF839) 117 147 1.6E-7 T 14-10-2018 IPR008557 Protein of unknown function DUF839 A4R43_22185 c38400eed9ce2b018c8cc9993e5e7006 386 Pfam PF05787 Bacterial protein of unknown function (DUF839) 150 240 8.6E-12 T 14-10-2018 IPR008557 Protein of unknown function DUF839 A4R43_13745 a2ddbd72b45b6289a42caf6d158f11cb 340 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 17 262 5.6E-66 T 14-10-2018 IPR014145 DNA ligase D, polymerase domain A4R43_13745 a2ddbd72b45b6289a42caf6d158f11cb 340 Gene3D G3DSA:3.90.920.30 24 300 7.2E-85 T 14-10-2018 A4R43_13690 39429ea603264f584d066755ed2accc3 154 Pfam PF03780 Asp23 family, cell envelope-related function 29 138 8.4E-30 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 A4R43_28760 f037cf329e7e284031479be5b285c10c 535 Gene3D G3DSA:3.40.50.2000 333 509 7.2E-41 T 14-10-2018 A4R43_28760 f037cf329e7e284031479be5b285c10c 535 SUPERFAMILY SSF53756 152 529 1.21E-63 T 14-10-2018 A4R43_28760 f037cf329e7e284031479be5b285c10c 535 Gene3D G3DSA:3.40.50.2000 151 330 4.7E-8 T 14-10-2018 A4R43_28760 f037cf329e7e284031479be5b285c10c 535 Pfam PF13439 Glycosyltransferase Family 4 162 318 3.1E-9 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4R43_28760 f037cf329e7e284031479be5b285c10c 535 Pfam PF00534 Glycosyl transferases group 1 341 500 6.4E-29 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 A4R43_17530 1b8b39c09e10c6d4d57a2ef6009bdd93 216 Gene3D G3DSA:3.40.430.10 1 211 7.5E-50 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_17530 1b8b39c09e10c6d4d57a2ef6009bdd93 216 SUPERFAMILY SSF53597 2 212 5.24E-40 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_17530 1b8b39c09e10c6d4d57a2ef6009bdd93 216 Pfam PF01872 RibD C-terminal domain 2 206 6.5E-39 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_03700 74aa6cbb510fd15abb986cc806907c34 220 Gene3D G3DSA:2.40.10.10 37 103 8.8E-15 T 14-10-2018 A4R43_03700 74aa6cbb510fd15abb986cc806907c34 220 SUPERFAMILY SSF50494 35 183 7.7E-18 T 14-10-2018 IPR009003 Peptidase S1, PA clan A4R43_03700 74aa6cbb510fd15abb986cc806907c34 220 Gene3D G3DSA:2.40.10.10 104 168 8.8E-15 T 14-10-2018 A4R43_21130 94c49ff55fa6755f164bec7638ba3c13 249 Pfam PF12730 ABC-2 family transporter protein 3 170 3.0E-8 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A4R43_20785 75a2a82537b450fc162dae20017fdf94 415 SUPERFAMILY SSF53448 21 251 3.45E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_20785 75a2a82537b450fc162dae20017fdf94 415 Pfam PF00535 Glycosyl transferase family 2 25 164 5.2E-24 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_20785 75a2a82537b450fc162dae20017fdf94 415 Pfam PF04138 GtrA-like protein 292 408 3.1E-10 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4R43_20785 75a2a82537b450fc162dae20017fdf94 415 Gene3D G3DSA:3.90.550.10 11 266 7.0E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 ProSitePatterns PS00756 Protein secY signature 2. 173 190 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 SUPERFAMILY SSF103491 2 425 2.09E-120 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 180 203 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 112 135 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 71 91 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 312 334 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 367 385 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 179 4.1E-98 T 14-10-2018 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 PIRSF PIRSF004557 1 435 1.4E-117 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 430 4.1E-129 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 434 28.345 T 14-10-2018 IPR026593 Protein translocase subunit SecY A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 Pfam PF00344 SecY translocase 72 418 9.5E-114 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_33950 e0fb6923006ba7cb13223da91bc083b2 435 Gene3D G3DSA:1.10.3370.10 1 430 8.6E-158 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4R43_36500 88b8cfff3b15c54aa4a56552d79b5d97 526 Pfam PF00561 alpha/beta hydrolase fold 99 493 2.0E-28 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_36500 88b8cfff3b15c54aa4a56552d79b5d97 526 SUPERFAMILY SSF53474 97 494 4.93E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25700 413dcc40564c752479c41a90abe1a67d 396 Pfam PF02687 FtsX-like permease family 303 391 4.1E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_25700 413dcc40564c752479c41a90abe1a67d 396 Pfam PF12704 MacB-like periplasmic core domain 30 238 4.3E-16 T 14-10-2018 IPR025857 MacB-like periplasmic core domain A4R43_33290 9d54d8aa96f5c9f0dd66a7ebfae8b0f4 243 Pfam PF13489 Methyltransferase domain 34 201 3.6E-15 T 14-10-2018 A4R43_33290 9d54d8aa96f5c9f0dd66a7ebfae8b0f4 243 SUPERFAMILY SSF53335 28 218 9.26E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_33290 9d54d8aa96f5c9f0dd66a7ebfae8b0f4 243 Gene3D G3DSA:3.40.50.150 32 223 9.7E-21 T 14-10-2018 A4R43_24815 5ed60187036de8b613db68fb2769d363 1032 Pfam PF01526 Tn3 transposase DDE domain 605 991 1.1E-130 T 14-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 A4R43_24815 5ed60187036de8b613db68fb2769d363 1032 Pfam PF13700 Domain of unknown function (DUF4158) 4 163 1.1E-29 T 14-10-2018 IPR025296 Domain of unknown function DUF4158 A4R43_39240 6dcca1fa63cc03702554363512901c88 275 Pfam PF01061 ABC-2 type transporter 28 238 3.1E-24 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_39240 6dcca1fa63cc03702554363512901c88 275 PIRSF PIRSF006648 9 273 9.6E-29 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39240 6dcca1fa63cc03702554363512901c88 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 1.6E-15 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39240 6dcca1fa63cc03702554363512901c88 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 44 65 1.6E-15 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39240 6dcca1fa63cc03702554363512901c88 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 217 236 1.6E-15 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39240 6dcca1fa63cc03702554363512901c88 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 161 185 1.6E-15 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39240 6dcca1fa63cc03702554363512901c88 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 124 149 1.6E-15 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_07835 ad9d6735329a5966e5916bb0411e851c 475 Gene3D G3DSA:3.40.605.10 15 465 2.5E-165 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_07835 ad9d6735329a5966e5916bb0411e851c 475 Gene3D G3DSA:3.40.309.10 247 435 2.5E-165 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_07835 ad9d6735329a5966e5916bb0411e851c 475 Pfam PF00171 Aldehyde dehydrogenase family 13 466 1.5E-159 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_07835 ad9d6735329a5966e5916bb0411e851c 475 SUPERFAMILY SSF53720 4 471 4.06E-159 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_03025 c05f5b079987835dd02137302a2d41f6 403 Gene3D G3DSA:1.20.1250.20 7 191 4.7E-14 T 14-10-2018 A4R43_03025 c05f5b079987835dd02137302a2d41f6 403 SUPERFAMILY SSF103473 8 383 4.97E-41 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_03025 c05f5b079987835dd02137302a2d41f6 403 Gene3D G3DSA:1.20.1250.20 198 384 4.7E-18 T 14-10-2018 A4R43_03025 c05f5b079987835dd02137302a2d41f6 403 Pfam PF07690 Major Facilitator Superfamily 18 324 1.3E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_30550 b35a7bde3a6f5781e4cf4c4bdb9a62da 286 SUPERFAMILY SSF53335 72 279 5.27E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_30550 b35a7bde3a6f5781e4cf4c4bdb9a62da 286 Pfam PF13489 Methyltransferase domain 80 265 1.7E-8 T 14-10-2018 A4R43_30550 b35a7bde3a6f5781e4cf4c4bdb9a62da 286 Gene3D G3DSA:3.40.50.150 53 274 2.6E-15 T 14-10-2018 A4R43_25665 8fcec54ba64ea9dd1dc794fa9fbf3a9c 271 Pfam PF01061 ABC-2 type transporter 21 227 2.0E-23 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_25665 8fcec54ba64ea9dd1dc794fa9fbf3a9c 271 PIRSF PIRSF006648 7 270 5.5E-26 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_31735 ec9ca6ed1bc7fb0c82f3a51691549d1b 391 SUPERFAMILY SSF53383 9 385 1.6E-96 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_31735 ec9ca6ed1bc7fb0c82f3a51691549d1b 391 Gene3D G3DSA:3.40.640.10 7 386 1.1E-119 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_31735 ec9ca6ed1bc7fb0c82f3a51691549d1b 391 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4R43_31735 ec9ca6ed1bc7fb0c82f3a51691549d1b 391 Pfam PF00155 Aminotransferase class I and II 34 380 9.3E-56 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4R43_13735 95af28fef3c97b038265ee0fa3142276 505 SUPERFAMILY SSF53474 107 491 5.61E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13735 95af28fef3c97b038265ee0fa3142276 505 Pfam PF08386 TAP-like protein 404 503 1.0E-20 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_32600 b6d813f782a1d1d78aa5f182e6e34e35 69 SUPERFAMILY SSF88659 39 67 2.32E-5 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_18425 ec3413404da2e63e18e78039311138c4 126 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 11 110 7.1E-21 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 A4R43_18425 ec3413404da2e63e18e78039311138c4 126 Hamap MF_00048 UPF0102 protein YraN [yraN]. 12 122 20.845 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 A4R43_18425 ec3413404da2e63e18e78039311138c4 126 Pfam PF02021 Uncharacterised protein family UPF0102 19 109 3.4E-26 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 A4R43_18425 ec3413404da2e63e18e78039311138c4 126 Gene3D G3DSA:3.40.1350.10 18 126 4.8E-28 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A4R43_18425 ec3413404da2e63e18e78039311138c4 126 SUPERFAMILY SSF52980 18 111 6.97E-20 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4R43_17240 919afd655ffb833b3be0134d61815e8d 171 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 15 99 8.6E-14 T 14-10-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp A4R43_17240 919afd655ffb833b3be0134d61815e8d 171 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 110 168 1.6E-12 T 14-10-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 Pfam PF03466 LysR substrate binding domain 90 287 8.9E-36 T 14-10-2018 IPR005119 LysR, substrate-binding A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 9.8E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 Gene3D G3DSA:3.40.190.290 92 290 2.5E-36 T 14-10-2018 A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 SUPERFAMILY SSF53850 93 288 1.76E-34 T 14-10-2018 A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 Gene3D G3DSA:1.10.10.10 1 89 4.0E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 SUPERFAMILY SSF46785 4 85 1.88E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17135 7dae024c458f0c8938bc8d36080b42a5 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4R43_17360 0a23340544d6fff8a1c8ce7c730051b9 209 SUPERFAMILY SSF53474 3 201 1.38E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_17360 0a23340544d6fff8a1c8ce7c730051b9 209 Pfam PF12697 Alpha/beta hydrolase family 7 199 5.9E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_17360 0a23340544d6fff8a1c8ce7c730051b9 209 Gene3D G3DSA:3.40.50.1820 1 205 1.5E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_37040 c2c202b29225a34e20de308806ef0eb6 252 Pfam PF07730 Histidine kinase 176 234 1.5E-12 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_11560 0680c24186bd07041345767f6f56d79c 471 SUPERFAMILY SSF51206 87 220 1.19E-19 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like A4R43_11560 0680c24186bd07041345767f6f56d79c 471 Gene3D G3DSA:2.60.120.10 74 228 6.1E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_11560 0680c24186bd07041345767f6f56d79c 471 Pfam PF00027 Cyclic nucleotide-binding domain 119 206 4.9E-11 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain A4R43_19740 a701789d0cf29bb95b969d8486c6d13d 260 SUPERFAMILY SSF52218 2 237 3.28E-57 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_19740 a701789d0cf29bb95b969d8486c6d13d 260 Pfam PF02525 Flavodoxin-like fold 1 197 2.0E-49 T 14-10-2018 IPR003680 Flavodoxin-like fold A4R43_19740 a701789d0cf29bb95b969d8486c6d13d 260 Gene3D G3DSA:3.40.50.360 1 254 3.7E-77 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_08840 f7f9c204a0b7852e24a6d17b09376ad1 339 Gene3D G3DSA:3.20.20.100 3 332 7.5E-107 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_08840 f7f9c204a0b7852e24a6d17b09376ad1 339 Pfam PF00248 Aldo/keto reductase family 18 311 1.4E-66 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_08840 f7f9c204a0b7852e24a6d17b09376ad1 339 SUPERFAMILY SSF51430 4 311 3.93E-88 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_13930 e54c9225632af77d5198451acd4dafe4 484 Gene3D G3DSA:1.20.1730.10 22 475 4.4E-74 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_13930 e54c9225632af77d5198451acd4dafe4 484 Pfam PF00474 Sodium:solute symporter family 32 418 1.3E-37 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_13910 a41f63ed87545278a8744f9430d5920a 342 Pfam PF06224 Winged helix DNA-binding domain 26 331 1.8E-56 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 A4R43_27310 28a99c298569e9ea16f33d1315165062 150 Gene3D G3DSA:1.10.10.10 6 85 1.2E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_27310 28a99c298569e9ea16f33d1315165062 150 Gene3D G3DSA:3.30.1490.190 87 149 1.0E-13 T 14-10-2018 A4R43_27310 28a99c298569e9ea16f33d1315165062 150 Pfam PF01475 Ferric uptake regulator family 15 105 2.5E-18 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4R43_27310 28a99c298569e9ea16f33d1315165062 150 SUPERFAMILY SSF46785 9 137 1.02E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_13150 bc82145f708ca1f234008258a0c9cb77 559 Pfam PF05960 Bacterial protein of unknown function (DUF885) 24 555 2.7E-141 T 14-10-2018 IPR010281 Protein of unknown function DUF885 A4R43_32695 2c199045911d0d60204b59515c1283fe 184 SUPERFAMILY SSF55826 30 179 2.62E-25 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4R43_32695 2c199045911d0d60204b59515c1283fe 184 Pfam PF04073 Aminoacyl-tRNA editing domain 48 168 1.3E-20 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4R43_32695 2c199045911d0d60204b59515c1283fe 184 Gene3D G3DSA:3.90.960.10 27 179 2.3E-25 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4R43_05550 6997b935e1d66e478213a90b6ad21974 153 Pfam PF00293 NUDIX domain 4 145 5.0E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_05550 6997b935e1d66e478213a90b6ad21974 153 Gene3D G3DSA:3.90.79.10 3 153 9.1E-20 T 14-10-2018 A4R43_05550 6997b935e1d66e478213a90b6ad21974 153 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4R43_05550 6997b935e1d66e478213a90b6ad21974 153 SUPERFAMILY SSF55811 4 152 2.17E-20 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_27655 38d7930da133d6fd52bd2a0016e55712 412 PIRSF PIRSF005962 19 412 3.8E-110 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 A4R43_27655 38d7930da133d6fd52bd2a0016e55712 412 SUPERFAMILY SSF55031 203 316 2.75E-30 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4R43_27655 38d7930da133d6fd52bd2a0016e55712 412 SUPERFAMILY SSF53187 20 410 1.11E-73 T 14-10-2018 A4R43_27655 38d7930da133d6fd52bd2a0016e55712 412 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 32 397 2.0E-104 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 A4R43_27655 38d7930da133d6fd52bd2a0016e55712 412 Pfam PF07687 Peptidase dimerisation domain 205 299 7.5E-11 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain A4R43_27655 38d7930da133d6fd52bd2a0016e55712 412 Gene3D G3DSA:3.30.70.360 201 315 8.0E-129 T 14-10-2018 A4R43_27655 38d7930da133d6fd52bd2a0016e55712 412 Pfam PF01546 Peptidase family M20/M25/M40 89 406 4.2E-31 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 A4R43_27655 38d7930da133d6fd52bd2a0016e55712 412 Gene3D G3DSA:3.40.630.10 32 395 8.0E-129 T 14-10-2018 A4R43_05405 715487c1bcdd7c10d379c8436e857d36 85 Pfam PF12277 Protein of unknown function (DUF3618) 13 54 3.0E-12 T 14-10-2018 IPR022062 Protein of unknown function DUF3618 A4R43_12685 a8e38504f2f60a3ab4b5bbf323a453f2 292 Pfam PF09851 Short C-terminal domain 263 289 1.6E-6 T 14-10-2018 IPR018649 SHOCT domain A4R43_12685 a8e38504f2f60a3ab4b5bbf323a453f2 292 Pfam PF14472 Domain of unknown function (DUF4429) 141 226 7.7E-20 T 14-10-2018 IPR027860 Domain of unknown function DUF4429 A4R43_12685 a8e38504f2f60a3ab4b5bbf323a453f2 292 Pfam PF14472 Domain of unknown function (DUF4429) 12 105 1.3E-14 T 14-10-2018 IPR027860 Domain of unknown function DUF4429 A4R43_40370 e5fbb72f801850444a1103fcde813e1a 122 SMART SM00960 1 90 9.3E-21 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_40370 e5fbb72f801850444a1103fcde813e1a 122 Gene3D G3DSA:3.30.450.30 1 120 1.6E-37 T 14-10-2018 A4R43_40370 e5fbb72f801850444a1103fcde813e1a 122 SUPERFAMILY SSF103196 2 119 1.88E-22 T 14-10-2018 A4R43_40370 e5fbb72f801850444a1103fcde813e1a 122 Pfam PF03259 Roadblock/LC7 domain 3 89 8.4E-21 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain A4R43_06840 85b5bae252a38b70a54c4cbdae1fa1c6 260 SUPERFAMILY SSF54060 41 253 1.41E-54 T 14-10-2018 A4R43_06840 85b5bae252a38b70a54c4cbdae1fa1c6 260 Pfam PF04231 Endonuclease I 44 253 3.1E-41 T 14-10-2018 IPR007346 Endonuclease I GO:0004518 A4R43_37590 8fa425a12a5e34a5070d6d9da6766297 281 Pfam PF13349 Putative adhesin 20 227 1.5E-7 T 14-10-2018 IPR025164 Putative adhesin A4R43_33375 54e578ca37093864d1c58c214353b23a 403 Pfam PF16169 Domain of unknown function (DUF4872) 195 331 9.1E-10 T 14-10-2018 IPR032369 Domain of unknown function DUF4872 A4R43_33375 54e578ca37093864d1c58c214353b23a 403 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 17 157 1.2E-23 T 14-10-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 A4R43_35785 730251eaff603f6268f830f14c214718 133 Gene3D G3DSA:3.90.79.10 1 126 1.9E-30 T 14-10-2018 A4R43_35785 730251eaff603f6268f830f14c214718 133 SUPERFAMILY SSF55811 3 127 3.11E-31 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_35785 730251eaff603f6268f830f14c214718 133 PRINTS PR00502 NUDIX hydrolase family signature 48 63 9.5E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_35785 730251eaff603f6268f830f14c214718 133 PRINTS PR00502 NUDIX hydrolase family signature 34 48 9.5E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4R43_35785 730251eaff603f6268f830f14c214718 133 Pfam PF00293 NUDIX domain 6 108 2.5E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_38525 0304b5679d3353f22dfc3d20ea759b72 391 Gene3D G3DSA:3.40.640.10 14 253 8.2E-81 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_38525 0304b5679d3353f22dfc3d20ea759b72 391 Gene3D G3DSA:3.90.1150.10 254 390 1.5E-34 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_38525 0304b5679d3353f22dfc3d20ea759b72 391 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 27 377 1.7E-111 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_38525 0304b5679d3353f22dfc3d20ea759b72 391 SUPERFAMILY SSF53383 13 388 9.46E-99 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_38525 0304b5679d3353f22dfc3d20ea759b72 391 PIRSF PIRSF000390 9 390 2.7E-110 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_10110 8fa7dbba5c781ca738a665150b45e902 305 PIRSF PIRSF001365 11 305 1.2E-57 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_10110 8fa7dbba5c781ca738a665150b45e902 305 SUPERFAMILY SSF51569 14 302 4.4E-66 T 14-10-2018 A4R43_10110 8fa7dbba5c781ca738a665150b45e902 305 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 8 303 1.2E-120 T 14-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 A4R43_10110 8fa7dbba5c781ca738a665150b45e902 305 SMART SM01130 13 304 1.7E-68 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_10110 8fa7dbba5c781ca738a665150b45e902 305 Pfam PF00701 Dihydrodipicolinate synthetase family 15 302 6.7E-49 T 14-10-2018 IPR002220 DapA-like GO:0016829 A4R43_10110 8fa7dbba5c781ca738a665150b45e902 305 Gene3D G3DSA:3.20.20.70 5 305 1.9E-94 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_10110 8fa7dbba5c781ca738a665150b45e902 305 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 13 304 42.88 T 14-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 A4R43_16630 87661b31741311d15de28644a2f31adb 438 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 151 421 2.9E-73 T 14-10-2018 IPR024516 Mammalian cell entry, C-terminal A4R43_16630 87661b31741311d15de28644a2f31adb 438 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 19 302 2.1E-58 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_16630 87661b31741311d15de28644a2f31adb 438 Pfam PF02470 MlaD protein 44 119 4.7E-11 T 14-10-2018 IPR003399 Mce/MlaD A4R43_04830 5e00ae83df43081006a052dd4a66b7e3 149 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 62 116 0.008 T 14-10-2018 IPR020535 Low molecular weight antigen Cfp6 A4R43_04830 5e00ae83df43081006a052dd4a66b7e3 149 Pfam PF10756 Bacterial PH domain 71 139 2.6E-18 T 14-10-2018 IPR019692 Protein of unknown function DUF2581 A4R43_06075 10c21d4834e0c3c973b1fd651acf5bd1 89 Gene3D G3DSA:3.40.30.10 5 85 1.4E-15 T 14-10-2018 A4R43_06075 10c21d4834e0c3c973b1fd651acf5bd1 89 Pfam PF00462 Glutaredoxin 9 65 1.6E-10 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A4R43_06075 10c21d4834e0c3c973b1fd651acf5bd1 89 SUPERFAMILY SSF52833 7 69 5.9E-11 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_00935 30d1e2d952dcc18fefba435a6c1e6fb9 212 SUPERFAMILY SSF100950 4 210 4.19E-71 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_00935 30d1e2d952dcc18fefba435a6c1e6fb9 212 Pfam PF01144 Coenzyme A transferase 7 200 2.9E-43 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_00935 30d1e2d952dcc18fefba435a6c1e6fb9 212 Gene3D G3DSA:3.40.1080.10 1 211 4.6E-98 T 14-10-2018 A4R43_00935 30d1e2d952dcc18fefba435a6c1e6fb9 212 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 1.7E-95 T 14-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 A4R43_00935 30d1e2d952dcc18fefba435a6c1e6fb9 212 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 14-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 A4R43_00935 30d1e2d952dcc18fefba435a6c1e6fb9 212 SMART SM00882 6 202 4.5E-75 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_22295 ce4ff9e9e7f0744f16b0615462c60621 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 256 2.7E-48 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_22295 ce4ff9e9e7f0744f16b0615462c60621 257 Gene3D G3DSA:1.10.12.10 201 257 6.7E-16 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_22295 ce4ff9e9e7f0744f16b0615462c60621 257 SUPERFAMILY SSF52096 3 256 8.3E-68 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_22295 ce4ff9e9e7f0744f16b0615462c60621 257 Gene3D G3DSA:3.90.226.10 6 198 4.6E-52 T 14-10-2018 A4R43_27035 983856dc24ec8ce4ef6475bc576677c6 362 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 15 355 3.9E-85 T 14-10-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like A4R43_27035 983856dc24ec8ce4ef6475bc576677c6 362 SUPERFAMILY SSF52540 125 335 4.25E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27035 983856dc24ec8ce4ef6475bc576677c6 362 Gene3D G3DSA:3.40.50.300 124 356 3.8E-23 T 14-10-2018 A4R43_26505 12e20a4345b8bce2d460f7e26bca23ab 272 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 268 5.6E-49 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4R43_26505 12e20a4345b8bce2d460f7e26bca23ab 272 Gene3D G3DSA:3.10.310.10 9 266 3.1E-66 T 14-10-2018 A4R43_26505 12e20a4345b8bce2d460f7e26bca23ab 272 PIRSF PIRSF016184 1 272 6.9E-56 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4R43_26505 12e20a4345b8bce2d460f7e26bca23ab 272 Gene3D G3DSA:3.10.310.10 115 264 3.1E-66 T 14-10-2018 A4R43_26505 12e20a4345b8bce2d460f7e26bca23ab 272 Pfam PF02567 Phenazine biosynthesis-like protein 9 268 4.6E-60 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4R43_26505 12e20a4345b8bce2d460f7e26bca23ab 272 SUPERFAMILY SSF54506 5 267 4.01E-55 T 14-10-2018 A4R43_35295 6b33cd6de88260b76fdab573ffe0a8c0 387 Pfam PF09594 Glycosyltransferase family 87 73 302 5.5E-47 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_11550 0e3554b67f4f6a486da030d27b1ab2f8 254 Pfam PF14023 Protein of unknown function (DUF4239) 49 245 5.5E-7 T 14-10-2018 IPR025333 Protein of unknown function DUF4239 A4R43_20990 02c26a67eca5566658528a102a3c20e9 201 SUPERFAMILY SSF52540 17 175 1.32E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20990 02c26a67eca5566658528a102a3c20e9 201 Gene3D G3DSA:3.40.50.300 10 191 7.9E-15 T 14-10-2018 A4R43_20990 02c26a67eca5566658528a102a3c20e9 201 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 2.7E-27 T 14-10-2018 IPR004130 GPN-loop GTPase A4R43_25795 0abb9e666d2c06603d38e05cd4778f70 76 Pfam PF10745 Protein of unknown function (DUF2530) 1 74 1.6E-22 T 14-10-2018 IPR019681 Protein of unknown function DUF2530 A4R43_39775 3318d8374e3e816527ad8c66df3519ac 376 Pfam PF07730 Histidine kinase 191 259 3.4E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_39775 3318d8374e3e816527ad8c66df3519ac 376 Gene3D G3DSA:3.30.565.10 255 371 4.3E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_39775 3318d8374e3e816527ad8c66df3519ac 376 SUPERFAMILY SSF55874 272 370 1.76E-7 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_37165 93ce336f73b8e5aec12c40140a8c8476 273 SUPERFAMILY SSF56059 87 242 1.86E-7 T 14-10-2018 A4R43_37165 93ce336f73b8e5aec12c40140a8c8476 273 Gene3D G3DSA:3.40.50.20 18 116 5.6E-7 T 14-10-2018 A4R43_35055 15ae6f6ee9046ea5ccd713c35eea295b 197 Gene3D G3DSA:2.60.120.10 2 156 1.6E-45 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_35055 15ae6f6ee9046ea5ccd713c35eea295b 197 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 171 34.654 T 14-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 A4R43_35055 15ae6f6ee9046ea5ccd713c35eea295b 197 Pfam PF03079 ARD/ARD' family 29 163 9.2E-27 T 14-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A4R43_35055 15ae6f6ee9046ea5ccd713c35eea295b 197 SUPERFAMILY SSF51182 8 180 6.58E-28 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_13275 f63a51502e5f4e753aedd0944d69c49a 277 SUPERFAMILY SSF53474 51 253 1.15E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13275 f63a51502e5f4e753aedd0944d69c49a 277 Gene3D G3DSA:3.40.50.1820 18 276 1.8E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_23915 60ccb6b537c658bf5dbc7b869027f8e7 173 Pfam PF04977 Septum formation initiator 64 138 1.9E-15 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC A4R43_19720 a0e471c692953e3a38d71062066d401a 143 Gene3D G3DSA:3.30.1490.190 86 143 2.7E-13 T 14-10-2018 A4R43_19720 a0e471c692953e3a38d71062066d401a 143 SUPERFAMILY SSF46785 6 136 6.34E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19720 a0e471c692953e3a38d71062066d401a 143 Gene3D G3DSA:1.10.10.10 3 84 2.0E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19720 a0e471c692953e3a38d71062066d401a 143 Pfam PF01475 Ferric uptake regulator family 14 128 3.3E-17 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4R43_33180 8aefaf4b6e23b0b348bce76132a98ec5 148 Pfam PF02575 YbaB/EbfC DNA-binding family 14 95 2.3E-11 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_33180 8aefaf4b6e23b0b348bce76132a98ec5 148 Gene3D G3DSA:3.30.1310.10 6 108 2.3E-7 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_33180 8aefaf4b6e23b0b348bce76132a98ec5 148 SUPERFAMILY SSF82607 10 93 1.57E-8 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_07045 f8848fbf836e7f684d8722bc50af55e8 435 Gene3D G3DSA:1.10.4080.10 92 429 2.6E-15 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_07045 f8848fbf836e7f684d8722bc50af55e8 435 Pfam PF03747 ADP-ribosylglycohydrolase 100 399 8.3E-52 T 14-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 A4R43_07045 f8848fbf836e7f684d8722bc50af55e8 435 SUPERFAMILY SSF101478 96 410 3.4E-36 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A4R43_40320 69bcd7603a1f886764ce1d83d1db172a 278 Pfam PF13649 Methyltransferase domain 51 146 9.7E-23 T 14-10-2018 A4R43_40320 69bcd7603a1f886764ce1d83d1db172a 278 SUPERFAMILY SSF53335 13 277 2.01E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_40320 69bcd7603a1f886764ce1d83d1db172a 278 Gene3D G3DSA:3.40.50.150 2 277 6.7E-44 T 14-10-2018 A4R43_15025 e36c4e0eb4781205af592b7cf2cfb88d 360 SUPERFAMILY SSF55874 261 358 2.82E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_15025 e36c4e0eb4781205af592b7cf2cfb88d 360 Gene3D G3DSA:3.30.565.10 241 359 1.0E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_15025 e36c4e0eb4781205af592b7cf2cfb88d 360 SUPERFAMILY SSF47336 163 231 5.89E-5 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_15025 e36c4e0eb4781205af592b7cf2cfb88d 360 Pfam PF07730 Histidine kinase 180 244 1.6E-18 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_16430 07a535d0e11fb49249a45078f1e1a6a8 150 Pfam PF07617 Protein of unknown function (DUF1579) 9 92 1.4E-9 T 14-10-2018 IPR011473 Protein of unknown function DUF1579 A4R43_38760 7d69802c5542270694c54f04845fa2b6 699 SUPERFAMILY SSF52266 475 694 5.55E-5 T 14-10-2018 A4R43_38760 7d69802c5542270694c54f04845fa2b6 699 Gene3D G3DSA:3.40.50.1110 470 694 1.3E-6 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_38760 7d69802c5542270694c54f04845fa2b6 699 Pfam PF01757 Acyltransferase family 23 348 8.4E-27 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A4R43_38015 f550012daa852e1887ab3549e832f149 255 SUPERFAMILY SSF53474 4 244 2.54E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38015 f550012daa852e1887ab3549e832f149 255 Pfam PF12697 Alpha/beta hydrolase family 17 240 8.1E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_38015 f550012daa852e1887ab3549e832f149 255 Gene3D G3DSA:3.40.50.1820 2 247 3.2E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01735 bcfdfd87143a3b6077a4df97dd81d9d0 526 Pfam PF13556 PucR C-terminal helix-turn-helix domain 459 517 6.2E-15 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_01735 bcfdfd87143a3b6077a4df97dd81d9d0 526 Gene3D G3DSA:1.10.10.2840 389 521 2.5E-12 T 14-10-2018 A4R43_01735 bcfdfd87143a3b6077a4df97dd81d9d0 526 Pfam PF07905 Purine catabolism regulatory protein-like family 7 128 1.2E-31 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain A4R43_40790 285544a299a1ac276851055fc714b8c8 387 Gene3D G3DSA:3.40.640.10 6 262 1.6E-71 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4R43_40790 285544a299a1ac276851055fc714b8c8 387 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 30 379 2.3E-100 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_40790 285544a299a1ac276851055fc714b8c8 387 PIRSF PIRSF000390 4 386 5.4E-97 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4R43_40790 285544a299a1ac276851055fc714b8c8 387 SUPERFAMILY SSF53383 28 382 5.3E-91 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4R43_40790 285544a299a1ac276851055fc714b8c8 387 Gene3D G3DSA:3.90.1150.10 264 386 1.1E-32 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4R43_04380 b3552fffa9f9345eb131bff47aa6c686 382 Pfam PF07907 YibE/F-like protein 128 366 6.5E-73 T 14-10-2018 IPR012507 YibE/F-like A4R43_20385 8068dba62c6272b77ed9736c253b7afc 326 Gene3D G3DSA:3.40.50.300 2 246 3.1E-64 T 14-10-2018 A4R43_20385 8068dba62c6272b77ed9736c253b7afc 326 Pfam PF13732 Domain of unknown function (DUF4162) 223 310 2.1E-6 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 A4R43_20385 8068dba62c6272b77ed9736c253b7afc 326 SMART SM00382 34 224 6.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_20385 8068dba62c6272b77ed9736c253b7afc 326 SUPERFAMILY SSF52540 5 232 1.41E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_20385 8068dba62c6272b77ed9736c253b7afc 326 Pfam PF00005 ABC transporter 27 168 1.3E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_35910 8ca69d2eed397e72e0cf546f903cd397 113 Pfam PF13806 Rieske-like [2Fe-2S] domain 8 110 7.5E-37 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 A4R43_35910 8ca69d2eed397e72e0cf546f903cd397 113 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 8 110 1.1E-34 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 A4R43_35910 8ca69d2eed397e72e0cf546f903cd397 113 SUPERFAMILY SSF50022 8 111 4.06E-36 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_35910 8ca69d2eed397e72e0cf546f903cd397 113 Gene3D G3DSA:2.102.10.10 2 111 7.9E-39 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4R43_11620 27e9e928ad0d449b46dee539c603777f 287 SUPERFAMILY SSF100939 1 259 1.28E-55 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily A4R43_11620 27e9e928ad0d449b46dee539c603777f 287 PIRSF PIRSF006493 1 287 2.5E-94 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_11620 27e9e928ad0d449b46dee539c603777f 287 SMART SM00559 52 180 7.1E-34 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A4R43_11620 27e9e928ad0d449b46dee539c603777f 287 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 256 9.9E-93 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_11620 27e9e928ad0d449b46dee539c603777f 287 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 254 33.561 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4R43_11620 27e9e928ad0d449b46dee539c603777f 287 Gene3D G3DSA:2.40.290.10 2 180 3.1E-19 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily A4R43_11620 27e9e928ad0d449b46dee539c603777f 287 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 190 5.4E-39 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A4R43_32300 e48c31c6aabc571e3837506cf7983715 212 SMART SM00563 28 147 4.2E-34 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_32300 e48c31c6aabc571e3837506cf7983715 212 Pfam PF01553 Acyltransferase 16 144 8.2E-25 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_32300 e48c31c6aabc571e3837506cf7983715 212 SUPERFAMILY SSF69593 5 206 1.07E-52 T 14-10-2018 A4R43_15640 6ceb3c153aeb2b1411c3bb1dddf4bb5f 289 PIRSF PIRSF006487 105 241 2.3E-6 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4R43_15640 6ceb3c153aeb2b1411c3bb1dddf4bb5f 289 Pfam PF09347 Domain of unknown function (DUF1989) 47 221 6.7E-65 T 14-10-2018 IPR018959 Protein of unknown function DUF1989 A4R43_13925 75533e308d1d72e59459d8fac0b90db0 498 Gene3D G3DSA:1.10.10.2840 373 497 1.1E-22 T 14-10-2018 A4R43_13925 75533e308d1d72e59459d8fac0b90db0 498 Pfam PF13556 PucR C-terminal helix-turn-helix domain 437 494 4.0E-23 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_13925 75533e308d1d72e59459d8fac0b90db0 498 Pfam PF07905 Purine catabolism regulatory protein-like family 38 137 6.1E-22 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain A4R43_40615 71f3837cae06c0ed520f52fc15710db9 159 SUPERFAMILY SSF69118 20 151 3.0E-28 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_40615 71f3837cae06c0ed520f52fc15710db9 159 Gene3D G3DSA:1.20.1290.10 16 153 3.1E-27 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4R43_40615 71f3837cae06c0ed520f52fc15710db9 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 102 1.4E-5 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4R43_21615 abf3806d0f6c64acd8f97b65b63e645d 163 SUPERFAMILY SSF56645 5 114 7.59E-14 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_21615 abf3806d0f6c64acd8f97b65b63e645d 163 Gene3D G3DSA:1.10.540.10 1 69 7.1E-12 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_22500 f3037780f43b5b640f46f5ecde15dbbb 408 SUPERFAMILY SSF88659 107 164 7.2E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_22500 f3037780f43b5b640f46f5ecde15dbbb 408 Pfam PF08281 Sigma-70, region 4 113 162 1.6E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4R43_22500 f3037780f43b5b640f46f5ecde15dbbb 408 Pfam PF04542 Sigma-70 region 2 9 74 2.7E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_22500 f3037780f43b5b640f46f5ecde15dbbb 408 Gene3D G3DSA:1.10.10.10 118 167 1.0E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_22500 f3037780f43b5b640f46f5ecde15dbbb 408 SUPERFAMILY SSF88946 9 85 2.2E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4R43_22500 f3037780f43b5b640f46f5ecde15dbbb 408 Gene3D G3DSA:1.10.1740.10 4 74 2.0E-6 T 14-10-2018 A4R43_22500 f3037780f43b5b640f46f5ecde15dbbb 408 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 165 1.2E-12 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4R43_01945 750495c919416ffa09347207ec4b7cbb 167 Pfam PF14016 Protein of unknown function (DUF4232) 32 160 1.7E-23 T 14-10-2018 IPR025326 Protein of unknown function DUF4232 A4R43_15490 40c30aeebaa7fb1282beb09ba1f7a1ce 111 Pfam PF11338 Protein of unknown function (DUF3140) 11 99 2.9E-27 T 14-10-2018 IPR021487 Protein of unknown function DUF3140 A4R43_25730 9e9522d5a83f19984ff8a0fa5f9a1081 290 Pfam PF11268 Protein of unknown function (DUF3071) 1 169 1.5E-59 T 14-10-2018 IPR021421 Protein of unknown function DUF3071 A4R43_33905 c16c63b9d9b10c37e0d1715740f92182 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.417 T 14-10-2018 IPR023053 Ribosomal protein S14, type Z A4R43_33905 c16c63b9d9b10c37e0d1715740f92182 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 14-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4R43_33905 c16c63b9d9b10c37e0d1715740f92182 61 SUPERFAMILY SSF57716 4 61 2.71E-21 T 14-10-2018 A4R43_33905 c16c63b9d9b10c37e0d1715740f92182 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 3.4E-25 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4R43_33905 c16c63b9d9b10c37e0d1715740f92182 61 Gene3D G3DSA:4.10.830.10 1 61 2.3E-31 T 14-10-2018 A4R43_10405 ed815ccfd458f3cc796a4d95c80afea8 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 311 2.7E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_30155 6d64bade5ff17a5af717fc60d0e12d97 247 Pfam PF02405 Permease MlaE 26 235 3.3E-58 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_09110 777a6239431a1b7a042b660058b7a256 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 298 1.3E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_09110 777a6239431a1b7a042b660058b7a256 311 SUPERFAMILY SSF161098 38 311 1.87E-57 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_09110 777a6239431a1b7a042b660058b7a256 311 Gene3D G3DSA:1.10.3720.10 32 303 7.2E-55 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06860 f0f56ba3a90ba10e09b69d3df8d63f08 244 Pfam PF01925 Sulfite exporter TauE/SafE 6 235 3.0E-30 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A4R43_23070 d0dec49c075c52063ecc6ea68f2e316c 233 SUPERFAMILY SSF161098 22 202 4.45E-32 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_23070 d0dec49c075c52063ecc6ea68f2e316c 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 213 1.5E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_23070 d0dec49c075c52063ecc6ea68f2e316c 233 Gene3D G3DSA:1.10.3720.10 20 213 1.7E-24 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_15805 3f9d192b570fa5972b5ebe7db562d2f4 214 PIRSF PIRSF035170 7 206 5.6E-46 T 14-10-2018 IPR009218 Predicted HD phosphohydrolase A4R43_15805 3f9d192b570fa5972b5ebe7db562d2f4 214 Gene3D G3DSA:1.10.3210.10 12 171 4.0E-10 T 14-10-2018 A4R43_15805 3f9d192b570fa5972b5ebe7db562d2f4 214 SUPERFAMILY SSF109604 18 194 3.07E-26 T 14-10-2018 A4R43_03690 f9f9df168ec27f365b2e362bb5fd1149 369 SUPERFAMILY SSF55874 244 364 1.02E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03690 f9f9df168ec27f365b2e362bb5fd1149 369 Gene3D G3DSA:3.30.565.10 239 365 6.2E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_38930 49df96570bb435bc518b1a4e88f1aa75 269 Gene3D G3DSA:3.40.50.150 8 266 7.8E-32 T 14-10-2018 A4R43_38930 49df96570bb435bc518b1a4e88f1aa75 269 Pfam PF13649 Methyltransferase domain 42 139 1.6E-14 T 14-10-2018 A4R43_38930 49df96570bb435bc518b1a4e88f1aa75 269 SUPERFAMILY SSF53335 11 267 2.26E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_17585 7d6a5e6a8f6a96665a1e3469ac4e55b2 65 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 28 63 1.0E-9 T 14-10-2018 A4R43_20850 25bcde790e51748f8fca105f7bd5d039 313 Gene3D G3DSA:3.40.50.1820 42 299 4.2E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20850 25bcde790e51748f8fca105f7bd5d039 313 SUPERFAMILY SSF53474 34 287 4.17E-10 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20850 25bcde790e51748f8fca105f7bd5d039 313 SUPERFAMILY SSF53474 148 311 2.03E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25770 9d420d6911679b1140bec54d88adc70f 249 Gene3D G3DSA:2.40.128.150 81 171 1.4E-73 T 14-10-2018 A4R43_25770 9d420d6911679b1140bec54d88adc70f 249 Pfam PF00797 N-acetyltransferase 17 244 6.5E-57 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4R43_25770 9d420d6911679b1140bec54d88adc70f 249 Gene3D G3DSA:3.30.2140.10 2 241 1.4E-73 T 14-10-2018 A4R43_25770 9d420d6911679b1140bec54d88adc70f 249 SUPERFAMILY SSF54001 2 246 7.6E-66 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_25770 9d420d6911679b1140bec54d88adc70f 249 PRINTS PR01543 Arylamine N-acetyltransferase signature 65 87 2.9E-10 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4R43_25770 9d420d6911679b1140bec54d88adc70f 249 PRINTS PR01543 Arylamine N-acetyltransferase signature 41 64 2.9E-10 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4R43_25770 9d420d6911679b1140bec54d88adc70f 249 PRINTS PR01543 Arylamine N-acetyltransferase signature 17 40 2.9E-10 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4R43_40385 f11b0cd943752fbe725fd4a2223b45b4 428 PRINTS PR00359 B-class P450 signature 164 186 1.5E-6 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40385 f11b0cd943752fbe725fd4a2223b45b4 428 PRINTS PR00359 B-class P450 signature 304 313 1.5E-6 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40385 f11b0cd943752fbe725fd4a2223b45b4 428 PRINTS PR00359 B-class P450 signature 242 253 1.5E-6 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40385 f11b0cd943752fbe725fd4a2223b45b4 428 PRINTS PR00359 B-class P450 signature 68 79 1.5E-6 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40385 f11b0cd943752fbe725fd4a2223b45b4 428 PRINTS PR00359 B-class P450 signature 114 130 1.5E-6 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4R43_40385 f11b0cd943752fbe725fd4a2223b45b4 428 Gene3D G3DSA:1.10.630.10 1 372 2.0E-73 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_40385 f11b0cd943752fbe725fd4a2223b45b4 428 SUPERFAMILY SSF48264 3 366 3.01E-51 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_38695 bf35fadc8d14f115324d91c981b511a6 231 Gene3D G3DSA:3.10.200.10 6 228 1.0E-45 T 14-10-2018 IPR036398 Alpha carbonic anhydrase domain superfamily A4R43_38695 bf35fadc8d14f115324d91c981b511a6 231 SUPERFAMILY SSF51069 18 225 3.01E-42 T 14-10-2018 IPR036398 Alpha carbonic anhydrase domain superfamily A4R43_38695 bf35fadc8d14f115324d91c981b511a6 231 SMART SM01057 5 229 2.0E-32 T 14-10-2018 IPR001148 Alpha carbonic anhydrase domain A4R43_38695 bf35fadc8d14f115324d91c981b511a6 231 Pfam PF00194 Eukaryotic-type carbonic anhydrase 17 227 3.5E-25 T 14-10-2018 IPR001148 Alpha carbonic anhydrase domain A4R43_02120 11f67eeb5e0829b51431fc7ac4031b84 196 Pfam PF03737 Aldolase/RraA 16 162 2.7E-41 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A4R43_02120 11f67eeb5e0829b51431fc7ac4031b84 196 SUPERFAMILY SSF89562 13 172 4.32E-40 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily A4R43_02120 11f67eeb5e0829b51431fc7ac4031b84 196 Gene3D G3DSA:3.50.30.100 7 184 2.5E-49 T 14-10-2018 A4R43_30320 1f3d7ec0f60f862310edd48c7ed29db4 293 SUPERFAMILY SSF53335 29 108 1.49E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_30320 1f3d7ec0f60f862310edd48c7ed29db4 293 Gene3D G3DSA:3.40.50.150 26 100 2.6E-10 T 14-10-2018 A4R43_30320 1f3d7ec0f60f862310edd48c7ed29db4 293 Pfam PF01555 DNA methylase 34 77 6.4E-7 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4R43_39030 c127370a8397084126c803cd9508874b 753 Gene3D G3DSA:3.40.390.10 269 383 4.0E-5 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A4R43_39030 c127370a8397084126c803cd9508874b 753 SUPERFAMILY SSF55486 275 394 1.27E-6 T 14-10-2018 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 PRINTS PR00143 Citrate synthase signature 330 344 1.0E-23 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 PRINTS PR00143 Citrate synthase signature 198 226 1.0E-23 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 PRINTS PR00143 Citrate synthase signature 310 326 1.0E-23 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 PRINTS PR00143 Citrate synthase signature 176 191 1.0E-23 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 PRINTS PR00143 Citrate synthase signature 251 271 1.0E-23 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 Pfam PF00285 Citrate synthase, C-terminal domain 23 359 3.8E-81 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 Gene3D G3DSA:1.10.230.10 225 327 2.4E-61 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 Gene3D G3DSA:1.10.580.10 82 359 2.4E-61 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 ProSitePatterns PS00480 Citrate synthase signature. 258 270 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 SUPERFAMILY SSF48256 17 370 4.19E-93 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 A4R43_25635 d28056eaf28f65dd79bc4f05b94dcd8b 382 Gene3D G3DSA:1.10.580.10 16 74 1.8E-11 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4R43_33245 8d4eb88af087e28afac0b313cffe38a3 257 SUPERFAMILY SSF52096 2 240 5.51E-56 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_33245 8d4eb88af087e28afac0b313cffe38a3 257 Gene3D G3DSA:3.90.226.10 1 247 9.1E-55 T 14-10-2018 A4R43_33245 8d4eb88af087e28afac0b313cffe38a3 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 6 223 6.3E-40 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_31325 f07838d02c6e25821425079b0d137375 153 Pfam PF05331 Protein of unknown function (DUF742) 41 153 8.6E-33 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_09715 52123d4528fcee8bbefd7ac79d71a840 114 Pfam PF00583 Acetyltransferase (GNAT) family 4 80 4.6E-10 T 14-10-2018 IPR000182 GNAT domain A4R43_09715 52123d4528fcee8bbefd7ac79d71a840 114 SUPERFAMILY SSF55729 2 87 1.05E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_09715 52123d4528fcee8bbefd7ac79d71a840 114 Gene3D G3DSA:3.40.630.30 1 92 2.1E-18 T 14-10-2018 A4R43_07420 cdcf554c9749d432b0c58c75a52093d8 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 261 1.6E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_07420 cdcf554c9749d432b0c58c75a52093d8 268 SUPERFAMILY SSF161098 8 268 2.49E-69 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_07420 cdcf554c9749d432b0c58c75a52093d8 268 Gene3D G3DSA:1.10.3720.10 2 255 3.1E-61 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_28235 1868dea300d4b336accba13e70315d61 79 Gene3D G3DSA:1.10.1200.10 1 79 2.9E-16 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_28235 1868dea300d4b336accba13e70315d61 79 SUPERFAMILY SSF47336 3 77 1.7E-10 T 14-10-2018 IPR036736 ACP-like superfamily A4R43_28235 1868dea300d4b336accba13e70315d61 79 Pfam PF00550 Phosphopantetheine attachment site 6 65 1.3E-4 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4R43_30380 8406c7a8e3033eeec6b29fb5eab3866d 77 Pfam PF05532 CsbD-like 11 60 8.5E-14 T 14-10-2018 IPR008462 CsbD-like domain A4R43_30380 8406c7a8e3033eeec6b29fb5eab3866d 77 SUPERFAMILY SSF69047 9 64 1.05E-8 T 14-10-2018 IPR036629 YjbJ superfamily A4R43_23140 efa53ee9208edc56ec9e672cff24b2fb 107 Pfam PF13490 Putative zinc-finger 15 48 2.5E-6 T 14-10-2018 IPR027383 Putative zinc-finger A4R43_23140 efa53ee9208edc56ec9e672cff24b2fb 107 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 14 87 6.5E-28 T 14-10-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA A4R43_23140 efa53ee9208edc56ec9e672cff24b2fb 107 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 9 87 1.1E-25 T 14-10-2018 IPR014295 Anti-sigma factor A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 Gene3D G3DSA:1.10.10.60 218 259 9.8E-18 T 14-10-2018 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 Gene3D G3DSA:1.10.10.60 16 58 4.4E-19 T 14-10-2018 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 SUPERFAMILY SSF46689 11 79 1.6E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 6.1E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 6.1E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 Gene3D G3DSA:1.10.357.10 261 395 2.4E-28 T 14-10-2018 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 Gene3D G3DSA:1.10.357.10 60 198 2.3E-19 T 14-10-2018 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 Pfam PF00440 Bacterial regulatory proteins, tetR family 223 269 8.2E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 67 8.2E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_21035 3dbbdb856704359c51e30cb456fc1707 395 SUPERFAMILY SSF46689 218 294 2.92E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31060 176bd38ceda0b55220d17fd5212d5a4b 398 Gene3D G3DSA:3.40.50.300 8 236 7.7E-9 T 14-10-2018 A4R43_31060 176bd38ceda0b55220d17fd5212d5a4b 398 Pfam PF13191 AAA ATPase domain 19 209 2.7E-22 T 14-10-2018 A4R43_31060 176bd38ceda0b55220d17fd5212d5a4b 398 SUPERFAMILY SSF52540 6 292 9.11E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_31060 176bd38ceda0b55220d17fd5212d5a4b 398 Gene3D G3DSA:1.10.10.10 320 385 1.4E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_09235 925e13d568ff981c85594cf6b3265165 261 Pfam PF13359 DDE superfamily endonuclease 104 255 5.7E-27 T 14-10-2018 IPR027806 Harbinger transposase-derived nuclease domain A4R43_09235 925e13d568ff981c85594cf6b3265165 261 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 85 3.9E-16 T 14-10-2018 IPR027805 Transposase, Helix-turn-helix domain A4R43_17170 3a43601853ff1dec8ffdc5207f9015de 134 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 18 100 2.2E-13 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_17170 3a43601853ff1dec8ffdc5207f9015de 134 Pfam PF04075 F420H(2)-dependent quinone reductase 11 97 8.3E-8 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_17170 3a43601853ff1dec8ffdc5207f9015de 134 Gene3D G3DSA:2.30.110.10 9 109 7.7E-11 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_01035 dbae22d9560c3a80694efa8d36c21348 254 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 8 204 3.2E-56 T 14-10-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 A4R43_01035 dbae22d9560c3a80694efa8d36c21348 254 Pfam PF03837 RecT family 24 204 1.6E-49 T 14-10-2018 IPR018330 RecT family GO:0003677|GO:0006259 A4R43_10165 7bbea420e2cc8ea9e4e50587cb70f6c3 253 Gene3D G3DSA:3.30.70.1230 6 167 1.5E-5 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_10165 7bbea420e2cc8ea9e4e50587cb70f6c3 253 SUPERFAMILY SSF55073 11 136 1.1E-5 T 14-10-2018 IPR029787 Nucleotide cyclase A4R43_21490 1943fe36ee1012e5cdcc415843d98283 145 SUPERFAMILY SSF52091 37 135 3.34E-12 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_21490 1943fe36ee1012e5cdcc415843d98283 145 Gene3D G3DSA:3.30.750.24 25 137 9.9E-22 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_24975 1bf480969ce3335926723692e5fd0937 166 Gene3D G3DSA:3.40.980.10 6 164 2.3E-45 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4R43_24975 1bf480969ce3335926723692e5fd0937 166 SUPERFAMILY SSF53218 10 159 1.3E-33 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4R43_24975 1bf480969ce3335926723692e5fd0937 166 Pfam PF00994 Probable molybdopterin binding domain 13 149 6.5E-26 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_24975 1bf480969ce3335926723692e5fd0937 166 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 10 149 1.1E-28 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_24975 1bf480969ce3335926723692e5fd0937 166 SMART SM00852 12 156 3.9E-19 T 14-10-2018 IPR001453 MoaB/Mog domain A4R43_21190 e1e93cfe5a38f87a9867b942f7d3b75b 265 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 106 2.5E-17 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_21190 e1e93cfe5a38f87a9867b942f7d3b75b 265 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 110 207 4.7E-12 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_21190 e1e93cfe5a38f87a9867b942f7d3b75b 265 Gene3D G3DSA:3.20.20.60 5 265 5.1E-77 T 14-10-2018 A4R43_21190 e1e93cfe5a38f87a9867b942f7d3b75b 265 SUPERFAMILY SSF51621 10 219 8.03E-56 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_21190 e1e93cfe5a38f87a9867b942f7d3b75b 265 PIRSF PIRSF015582 4 265 8.2E-72 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like A4R43_10530 96b751cbf9d114c4e5530b1a7de84021 117 SUPERFAMILY SSF142906 3 115 3.53E-41 T 14-10-2018 IPR038056 YjbR-like superfamily A4R43_10530 96b751cbf9d114c4e5530b1a7de84021 117 Gene3D G3DSA:3.90.1150.30 2 117 8.3E-45 T 14-10-2018 IPR038056 YjbR-like superfamily A4R43_10530 96b751cbf9d114c4e5530b1a7de84021 117 Pfam PF04237 YjbR 11 101 5.4E-31 T 14-10-2018 IPR007351 Uncharacterised protein YjbR A4R43_04295 f0c12a62a55f43fb8a2f95b30ffadee1 234 Pfam PF03591 AzlC protein 19 155 9.5E-36 T 14-10-2018 IPR011606 Branched-chain amino acid transport, permease A4R43_23325 a41bf048ec0af36991f6a668cc898d0e 277 Gene3D G3DSA:3.40.50.10320 4 277 7.5E-97 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_23325 a41bf048ec0af36991f6a668cc898d0e 277 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 9 276 38.487 T 14-10-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 A4R43_23325 a41bf048ec0af36991f6a668cc898d0e 277 SUPERFAMILY SSF102588 6 265 7.06E-63 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_23325 a41bf048ec0af36991f6a668cc898d0e 277 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 10 275 2.0E-102 T 14-10-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 A4R43_23325 a41bf048ec0af36991f6a668cc898d0e 277 Pfam PF02585 GlcNAc-PI de-N-acetylase 10 160 1.5E-25 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4R43_37960 1ef83d2affbbc71f8dc05818f50339b8 246 Gene3D G3DSA:3.40.50.10310 1 244 2.9E-55 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_37960 1ef83d2affbbc71f8dc05818f50339b8 246 Pfam PF02633 Creatinine amidohydrolase 5 238 3.8E-52 T 14-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_37960 1ef83d2affbbc71f8dc05818f50339b8 246 SUPERFAMILY SSF102215 1 241 3.01E-47 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4R43_19345 747c7e04ff0264bfacef744be840fd94 253 SMART SM00420 6 58 2.2E-12 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_19345 747c7e04ff0264bfacef744be840fd94 253 SUPERFAMILY SSF46785 4 60 3.03E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_19345 747c7e04ff0264bfacef744be840fd94 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.4E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_19345 747c7e04ff0264bfacef744be840fd94 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.4E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_19345 747c7e04ff0264bfacef744be840fd94 253 SUPERFAMILY SSF100950 75 235 2.72E-27 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_19345 747c7e04ff0264bfacef744be840fd94 253 SMART SM01134 73 234 8.8E-69 T 14-10-2018 A4R43_19345 747c7e04ff0264bfacef744be840fd94 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 3.4E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4R43_19345 747c7e04ff0264bfacef744be840fd94 253 Pfam PF00455 DeoR C terminal sensor domain 76 232 2.6E-50 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain A4R43_39175 119330d3c7d666135f927ee8c71ea886 350 Pfam PF02720 Domain of unknown function (DUF222) 1 255 2.0E-9 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_32975 8797f9e031269ce9f22dfc6e3de098ab 533 Pfam PF05140 ResB-like family 35 521 1.4E-129 T 14-10-2018 IPR007816 ResB-like domain A4R43_09425 7a5bd82f90d1fb3b03c8da2f5bbbe8cd 289 Pfam PF01636 Phosphotransferase enzyme family 25 240 9.7E-6 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_09425 7a5bd82f90d1fb3b03c8da2f5bbbe8cd 289 SUPERFAMILY SSF56112 2 254 1.44E-14 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_33525 aeeae41268507c0f8e50dfdd06107c54 311 Pfam PF10756 Bacterial PH domain 207 281 5.0E-5 T 14-10-2018 IPR019692 Protein of unknown function DUF2581 A4R43_00265 4388aac844c362fff53b00c7dd35aae7 247 SMART SM00382 31 217 1.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_00265 4388aac844c362fff53b00c7dd35aae7 247 Gene3D G3DSA:3.40.50.300 4 242 1.3E-57 T 14-10-2018 A4R43_00265 4388aac844c362fff53b00c7dd35aae7 247 Pfam PF00005 ABC transporter 22 166 2.3E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_00265 4388aac844c362fff53b00c7dd35aae7 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 217 239 1.6E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4R43_00265 4388aac844c362fff53b00c7dd35aae7 247 SUPERFAMILY SSF52540 6 240 1.21E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_10195 ce910860f6e30f7ad4d500f68bd60254 147 SUPERFAMILY SSF47413 27 84 4.36E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_10195 ce910860f6e30f7ad4d500f68bd60254 147 Gene3D G3DSA:1.10.260.40 4 135 6.1E-50 T 14-10-2018 A4R43_05075 56be647b6ee6ddceec1a02d42d418f43 238 Pfam PF00117 Glutamine amidotransferase class-I 42 220 1.1E-10 T 14-10-2018 IPR017926 Glutamine amidotransferase A4R43_05075 56be647b6ee6ddceec1a02d42d418f43 238 Gene3D G3DSA:3.40.50.880 5 229 1.6E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_05075 56be647b6ee6ddceec1a02d42d418f43 238 SUPERFAMILY SSF52317 7 228 1.42E-35 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_14110 5c33384d12c7af6cfa01e2ff2d7fd40a 187 SUPERFAMILY SSF46689 16 69 1.99E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14110 5c33384d12c7af6cfa01e2ff2d7fd40a 187 SUPERFAMILY SSF48498 83 156 3.2E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_14110 5c33384d12c7af6cfa01e2ff2d7fd40a 187 Gene3D G3DSA:1.10.357.10 5 186 6.2E-37 T 14-10-2018 A4R43_14110 5c33384d12c7af6cfa01e2ff2d7fd40a 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 57 3.9E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_22205 4b88fcbb3d34733faf9aeec52af811e6 251 SUPERFAMILY SSF53474 10 220 5.92E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_22205 4b88fcbb3d34733faf9aeec52af811e6 251 Gene3D G3DSA:3.40.50.1820 11 221 6.5E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_23085 d439963f9ec4d5cf71a06568acfb89eb 460 Gene3D G3DSA:3.40.50.150 86 300 3.6E-53 T 14-10-2018 A4R43_23085 d439963f9ec4d5cf71a06568acfb89eb 460 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 199 205 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4R43_23085 d439963f9ec4d5cf71a06568acfb89eb 460 SUPERFAMILY SSF53335 143 261 8.76E-9 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_23085 d439963f9ec4d5cf71a06568acfb89eb 460 Pfam PF01861 Protein of unknown function DUF43 93 272 2.8E-24 T 14-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal A4R43_04890 92e3bef4d84455032bf30c89dd686276 209 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 5 180 1.2E-32 T 14-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 A4R43_04890 92e3bef4d84455032bf30c89dd686276 209 Gene3D G3DSA:1.10.3630.10 3 114 2.8E-9 T 14-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily A4R43_34545 90b8fce5de3b26f80ed37422de355098 300 Pfam PF04657 Putative inner membrane exporter, YdcZ 150 283 2.6E-17 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ A4R43_34545 90b8fce5de3b26f80ed37422de355098 300 Pfam PF04657 Putative inner membrane exporter, YdcZ 1 133 2.2E-25 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ A4R43_39235 4507db3faeebc890a349cffe884b187f 266 PRINTS PR00164 ABC-2 type transport system membrane protein signature 187 206 1.9E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39235 4507db3faeebc890a349cffe884b187f 266 PRINTS PR00164 ABC-2 type transport system membrane protein signature 112 137 1.9E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39235 4507db3faeebc890a349cffe884b187f 266 PRINTS PR00164 ABC-2 type transport system membrane protein signature 207 226 1.9E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39235 4507db3faeebc890a349cffe884b187f 266 PRINTS PR00164 ABC-2 type transport system membrane protein signature 34 55 1.9E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_39235 4507db3faeebc890a349cffe884b187f 266 Pfam PF01061 ABC-2 type transporter 24 228 1.2E-17 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_39235 4507db3faeebc890a349cffe884b187f 266 PIRSF PIRSF006648 20 265 1.0E-20 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_03875 1c6ead73a64820e71aa1ea818038797d 384 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 175 276 2.6E-14 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_03875 1c6ead73a64820e71aa1ea818038797d 384 SUPERFAMILY SSF52266 169 372 2.17E-23 T 14-10-2018 A4R43_03875 1c6ead73a64820e71aa1ea818038797d 384 Gene3D G3DSA:2.60.120.260 9 162 9.6E-42 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily A4R43_03875 1c6ead73a64820e71aa1ea818038797d 384 Gene3D G3DSA:3.40.50.1110 169 377 8.2E-66 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_10125 c7d16d7e93403f628d80a9b95a0b9ffc 304 Pfam PF03547 Membrane transport protein 156 297 3.3E-14 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4R43_10125 c7d16d7e93403f628d80a9b95a0b9ffc 304 Pfam PF03547 Membrane transport protein 9 132 2.3E-8 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4R43_18660 dd86724b53e4fe5a848809e11dbb4308 263 Pfam PF11580 Protein of unknown function (DUF3239) 90 207 1.9E-29 T 14-10-2018 IPR021632 Protein of unknown function DUF3239 A4R43_18660 dd86724b53e4fe5a848809e11dbb4308 263 Gene3D G3DSA:2.40.410.10 86 220 1.2E-25 T 14-10-2018 IPR023124 DUF3239 domain superfamily A4R43_31905 3ef30b987a1fdba0bc6200f160b65e8e 126 SUPERFAMILY SSF55718 32 124 2.05E-7 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A4R43_31905 3ef30b987a1fdba0bc6200f160b65e8e 126 Gene3D G3DSA:3.30.1050.40 1 126 3.1E-52 T 14-10-2018 A4R43_04940 a3301236c45849fe0aad3b83b6694fee 369 SUPERFAMILY SSF55874 273 367 4.01E-7 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_04940 a3301236c45849fe0aad3b83b6694fee 369 Gene3D G3DSA:3.30.565.10 245 367 5.4E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_04940 a3301236c45849fe0aad3b83b6694fee 369 Pfam PF07730 Histidine kinase 175 238 1.9E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_30255 72207ff33fbb745e9ce3a3e11a24c1b3 838 Gene3D G3DSA:3.40.50.300 602 759 4.0E-16 T 14-10-2018 A4R43_30255 72207ff33fbb745e9ce3a3e11a24c1b3 838 Pfam PF01935 Domain of unknown function DUF87 424 499 1.3E-7 T 14-10-2018 IPR002789 Helicase HerA, central domain A4R43_30255 72207ff33fbb745e9ce3a3e11a24c1b3 838 SUPERFAMILY SSF52540 402 756 2.76E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_30255 72207ff33fbb745e9ce3a3e11a24c1b3 838 Pfam PF12696 TraM recognition site of TraD and TraG 685 754 1.1E-5 T 14-10-2018 IPR032689 TraD/TraG, TraM recognition site A4R43_30255 72207ff33fbb745e9ce3a3e11a24c1b3 838 Gene3D G3DSA:3.40.50.300 415 561 1.7E-11 T 14-10-2018 A4R43_35765 79b1c29a220f4ed06899054eb44035d3 357 SUPERFAMILY SSF144083 292 354 9.94E-20 T 14-10-2018 A4R43_35765 79b1c29a220f4ed06899054eb44035d3 357 SUPERFAMILY SSF143865 27 289 1.24E-70 T 14-10-2018 A4R43_35765 79b1c29a220f4ed06899054eb44035d3 357 Gene3D G3DSA:1.20.58.340 169 279 7.3E-34 T 14-10-2018 A4R43_35765 79b1c29a220f4ed06899054eb44035d3 357 Gene3D G3DSA:1.20.58.340 280 357 7.3E-25 T 14-10-2018 A4R43_35765 79b1c29a220f4ed06899054eb44035d3 357 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 52 357 7.4E-63 T 14-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A4R43_35765 79b1c29a220f4ed06899054eb44035d3 357 Pfam PF01544 CorA-like Mg2+ transporter protein 59 353 1.7E-66 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4R43_35765 79b1c29a220f4ed06899054eb44035d3 357 Gene3D G3DSA:3.30.460.20 26 168 1.6E-30 T 14-10-2018 A4R43_31375 7f1daac0ea431d9cd8ed88b82200a376 177 Pfam PF01161 Phosphatidylethanolamine-binding protein 42 171 1.5E-34 T 14-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A4R43_31375 7f1daac0ea431d9cd8ed88b82200a376 177 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 41 171 2.9E-34 T 14-10-2018 IPR005247 YbhB/YbcL A4R43_31375 7f1daac0ea431d9cd8ed88b82200a376 177 Gene3D G3DSA:3.90.280.10 2 175 1.7E-51 T 14-10-2018 IPR036610 PEBP-like superfamily A4R43_31375 7f1daac0ea431d9cd8ed88b82200a376 177 SUPERFAMILY SSF49777 17 174 6.28E-45 T 14-10-2018 IPR036610 PEBP-like superfamily A4R43_16080 bbbb7430f407ccbfe52028529dd28b4f 388 SUPERFAMILY SSF53901 6 233 2.59E-22 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_16080 bbbb7430f407ccbfe52028529dd28b4f 388 Gene3D G3DSA:3.40.47.10 2 387 3.1E-94 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_16080 bbbb7430f407ccbfe52028529dd28b4f 388 PIRSF PIRSF000429 1 378 1.3E-19 T 14-10-2018 IPR002155 Thiolase GO:0016747 A4R43_16080 bbbb7430f407ccbfe52028529dd28b4f 388 SUPERFAMILY SSF53901 262 383 1.02E-13 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 A4R43_16080 bbbb7430f407ccbfe52028529dd28b4f 388 Pfam PF00108 Thiolase, N-terminal domain 24 226 2.0E-6 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A4R43_00645 453621bd3a8ccc40504e2ddacf69380d 308 SUPERFAMILY SSF54593 4 219 5.19E-8 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_00645 453621bd3a8ccc40504e2ddacf69380d 308 Gene3D G3DSA:3.10.180.10 4 169 3.7E-10 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_00645 453621bd3a8ccc40504e2ddacf69380d 308 Pfam PF13468 Glyoxalase-like domain 6 211 2.9E-23 T 14-10-2018 IPR025870 Glyoxalase-like domain A4R43_24695 f9150dac26d21e51534d682e11a2ae5f 991 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 723 979 8.7E-48 T 14-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain A4R43_24695 f9150dac26d21e51534d682e11a2ae5f 991 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 724 980 7.6E-19 T 14-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain A4R43_24695 f9150dac26d21e51534d682e11a2ae5f 991 Pfam PF04738 Lantibiotic dehydratase, C terminus 11 653 1.1E-200 T 14-10-2018 IPR006827 Lantibiotic dehydratase, N-terminal A4R43_41725 c0b5f638e8306aa8b7039ff1a61bf57f 144 Gene3D G3DSA:3.10.180.10 2 144 3.5E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_41725 c0b5f638e8306aa8b7039ff1a61bf57f 144 SUPERFAMILY SSF54593 8 143 5.79E-8 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_24255 6135f26de4ac8b4483379f415662ad55 107 Pfam PF11855 Protein of unknown function (DUF3375) 55 91 1.2E-8 T 14-10-2018 IPR021804 Protein of unknown function DUF3375 A4R43_24255 6135f26de4ac8b4483379f415662ad55 107 Pfam PF11855 Protein of unknown function (DUF3375) 9 56 5.5E-14 T 14-10-2018 IPR021804 Protein of unknown function DUF3375 A4R43_34770 8ab47a5ab5a568aeff778c85c52a9f69 132 Gene3D G3DSA:3.40.140.10 2 131 1.0E-41 T 14-10-2018 A4R43_34770 8ab47a5ab5a568aeff778c85c52a9f69 132 Pfam PF08211 Cytidine and deoxycytidylate deaminase zinc-binding region 9 59 2.0E-8 T 14-10-2018 IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 A4R43_34770 8ab47a5ab5a568aeff778c85c52a9f69 132 SUPERFAMILY SSF53927 7 130 1.09E-35 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4R43_27505 4f4af26fae9a2caf2ea7e60691efefa0 283 PIRSF PIRSF017393 1 283 8.9E-79 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_27505 4f4af26fae9a2caf2ea7e60691efefa0 283 Pfam PF04672 S-adenosyl methyltransferase 10 282 6.9E-76 T 14-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4R43_27505 4f4af26fae9a2caf2ea7e60691efefa0 283 SUPERFAMILY SSF53335 12 254 1.1E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_27505 4f4af26fae9a2caf2ea7e60691efefa0 283 Gene3D G3DSA:3.40.50.150 1 282 5.5E-96 T 14-10-2018 A4R43_28740 bb3cbd599c1b0b441af6844ebbf394f3 549 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 128 231 6.2E-6 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4R43_22175 df959603ef5b544a7c00d2286f62a91a 510 Pfam PF00561 alpha/beta hydrolase fold 95 483 1.7E-48 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_22175 df959603ef5b544a7c00d2286f62a91a 510 SUPERFAMILY SSF53474 88 493 4.02E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_24140 afbbe16162b080d6a68af61915673d68 525 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 332 524 2.2E-17 T 14-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 A4R43_24140 afbbe16162b080d6a68af61915673d68 525 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 50 296 1.1E-11 T 14-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 A4R43_27930 194e51f26e82bee9309fac875be95e38 407 Pfam PF07730 Histidine kinase 217 282 4.9E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_27930 194e51f26e82bee9309fac875be95e38 407 Pfam PF13796 Putative sensor 14 188 6.6E-15 T 14-10-2018 IPR025828 Putative sensor domain A4R43_27930 194e51f26e82bee9309fac875be95e38 407 SUPERFAMILY SSF55874 293 402 5.31E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_27930 194e51f26e82bee9309fac875be95e38 407 Gene3D G3DSA:3.30.565.10 286 405 4.4E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_12195 335d7928b2d4c99a2f11f6344cc49db7 185 Gene3D G3DSA:3.40.1000.10 12 159 6.7E-6 T 14-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich A4R43_20080 092b51046c43d57692564b99e308d292 322 SUPERFAMILY SSF51726 47 317 4.06E-25 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_20080 092b51046c43d57692564b99e308d292 322 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 3 313 3.6E-12 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4R43_20080 092b51046c43d57692564b99e308d292 322 Gene3D G3DSA:3.20.20.210 54 318 1.3E-23 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_31970 164a079e5d7a2ed87a6d2388e009cf29 504 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 437 6.9E-141 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A4R43_25915 28928b3b9b575d9e6b9f4d2dbfbe1193 276 SUPERFAMILY SSF51695 33 271 1.7E-15 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A4R43_25915 28928b3b9b575d9e6b9f4d2dbfbe1193 276 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 233 268 1.2E-10 T 14-10-2018 A4R43_22155 9d872fdb9abaa4efab97ffbf9cb96856 432 SUPERFAMILY SSF103473 12 421 9.55E-58 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_22155 9d872fdb9abaa4efab97ffbf9cb96856 432 Pfam PF07690 Major Facilitator Superfamily 27 383 1.5E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_22155 9d872fdb9abaa4efab97ffbf9cb96856 432 Gene3D G3DSA:1.20.1250.20 6 422 2.3E-48 T 14-10-2018 A4R43_18905 386861bbee931ba791dd255500c92b4b 124 Pfam PF04341 Protein of unknown function, DUF485 22 107 1.6E-34 T 14-10-2018 IPR007436 Protein of unknown function DUF485 A4R43_24400 67930c47c931a6b167e8cc2a61c8f68a 118 Gene3D G3DSA:1.10.10.60 8 55 1.0E-6 T 14-10-2018 A4R43_04985 8f9fbc613ef106c4e2e636afe31a24a3 114 SUPERFAMILY SSF46785 8 109 5.82E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_04985 8f9fbc613ef106c4e2e636afe31a24a3 114 Gene3D G3DSA:1.10.10.10 3 111 2.3E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_04985 8f9fbc613ef106c4e2e636afe31a24a3 114 Pfam PF01638 HxlR-like helix-turn-helix 18 106 5.4E-25 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_41025 2d85b225ae50f8dc1439cc1cee76145f 504 PIRSF PIRSF026631 17 491 2.4E-60 T 14-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 A4R43_41025 2d85b225ae50f8dc1439cc1cee76145f 504 Pfam PF03703 Bacterial PH domain 414 473 1.8E-6 T 14-10-2018 IPR005182 Domain of unknown function DUF304 A4R43_41025 2d85b225ae50f8dc1439cc1cee76145f 504 Pfam PF03703 Bacterial PH domain 73 147 3.7E-10 T 14-10-2018 IPR005182 Domain of unknown function DUF304 A4R43_16025 189955fe3cc56f5b51ac038bc4b7bfa4 339 PIRSF PIRSF015921 8 339 4.1E-76 T 14-10-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 A4R43_16025 189955fe3cc56f5b51ac038bc4b7bfa4 339 Pfam PF00487 Fatty acid desaturase 59 317 4.0E-41 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_33140 0c41b7bd3ed6e884bffa9149ee78b7cb 516 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 137 156 3.4E-28 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33140 0c41b7bd3ed6e884bffa9149ee78b7cb 516 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 3.4E-28 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33140 0c41b7bd3ed6e884bffa9149ee78b7cb 516 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 3.4E-28 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33140 0c41b7bd3ed6e884bffa9149ee78b7cb 516 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 3.4E-28 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33140 0c41b7bd3ed6e884bffa9149ee78b7cb 516 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 244 268 3.4E-28 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33140 0c41b7bd3ed6e884bffa9149ee78b7cb 516 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 5 511 2.4E-161 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_33140 0c41b7bd3ed6e884bffa9149ee78b7cb 516 Pfam PF00361 Proton-conducting membrane transporter 131 425 8.1E-58 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_39660 f75c1a7c46bd1129172561ad2d1199c0 195 SUPERFAMILY SSF55486 5 148 5.86E-37 T 14-10-2018 A4R43_39660 f75c1a7c46bd1129172561ad2d1199c0 195 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 14-10-2018 IPR020549 Endoribonuclease YbeY, conserved site A4R43_39660 f75c1a7c46bd1129172561ad2d1199c0 195 Pfam PF02130 Uncharacterized protein family UPF0054 18 148 4.0E-36 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4R43_39660 f75c1a7c46bd1129172561ad2d1199c0 195 Gene3D G3DSA:3.40.390.30 1 157 1.2E-35 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 A4R43_39660 f75c1a7c46bd1129172561ad2d1199c0 195 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 2.3E-31 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4R43_39660 f75c1a7c46bd1129172561ad2d1199c0 195 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 20.296 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4R43_41000 9d6fd13db963623673e4a2a4f77f862e 215 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 199 1.1E-34 T 14-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 A4R43_41000 9d6fd13db963623673e4a2a4f77f862e 215 Gene3D G3DSA:1.10.3630.10 2 196 7.2E-8 T 14-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily A4R43_10705 93c36d66d9a43e98a261589628e41688 241 Pfam PF14230 Domain of unknown function (DUF4333) 155 231 1.1E-20 T 14-10-2018 IPR025637 Domain of unknown function DUF4333 A4R43_25750 d68898e106cc9f8807d618e294bea996 498 Gene3D G3DSA:3.30.590.20 41 470 1.7E-58 T 14-10-2018 A4R43_25750 d68898e106cc9f8807d618e294bea996 498 PIRSF PIRSF012666 1 498 3.1E-208 T 14-10-2018 IPR016602 Uncharacterised conserved protein UCP012666 A4R43_25750 d68898e106cc9f8807d618e294bea996 498 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 195 250 2.0E-4 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4R43_25750 d68898e106cc9f8807d618e294bea996 498 SUPERFAMILY SSF55931 38 464 4.61E-53 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 PRINTS PR00412 Epoxide hydrolase signature 26 44 1.3E-10 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 PRINTS PR00412 Epoxide hydrolase signature 104 117 1.3E-10 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 PRINTS PR00412 Epoxide hydrolase signature 238 260 1.3E-10 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 PRINTS PR00412 Epoxide hydrolase signature 46 61 1.3E-10 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 6.1E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 6.1E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 6.1E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 6.1E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 Gene3D G3DSA:3.40.50.1820 4 267 6.7E-68 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 Pfam PF12697 Alpha/beta hydrolase family 22 253 2.4E-19 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_25320 f3f74cb5eceee371ee717d28205a5629 276 SUPERFAMILY SSF53474 3 261 4.9E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_06400 4e07802f8258b306ed333ed6aba35ad6 312 SUPERFAMILY SSF161098 68 295 4.58E-58 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_06400 4e07802f8258b306ed333ed6aba35ad6 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 300 8.4E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_06400 4e07802f8258b306ed333ed6aba35ad6 312 Gene3D G3DSA:1.10.3720.10 64 307 1.1E-66 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_05335 733d804a5b5abf72915da439da7e182e 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 106 5.6E-12 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_05335 733d804a5b5abf72915da439da7e182e 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 216 373 3.6E-18 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4R43_05335 733d804a5b5abf72915da439da7e182e 392 SUPERFAMILY SSF47203 216 375 1.05E-16 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4R43_05335 733d804a5b5abf72915da439da7e182e 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 110 193 1.7E-18 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4R43_05335 733d804a5b5abf72915da439da7e182e 392 Gene3D G3DSA:2.40.110.10 110 220 4.2E-36 T 14-10-2018 A4R43_05335 733d804a5b5abf72915da439da7e182e 392 Gene3D G3DSA:1.10.540.10 2 105 1.1E-17 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_05335 733d804a5b5abf72915da439da7e182e 392 SUPERFAMILY SSF56645 15 229 4.58E-63 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_05335 733d804a5b5abf72915da439da7e182e 392 Gene3D G3DSA:1.20.140.10 221 380 1.5E-28 T 14-10-2018 A4R43_06130 1c90dddedb57fd1c8d4a320924ee6a3f 292 Gene3D G3DSA:3.20.20.30 1 286 4.0E-65 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_06130 1c90dddedb57fd1c8d4a320924ee6a3f 292 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 11 234 2.9E-91 T 14-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c A4R43_06130 1c90dddedb57fd1c8d4a320924ee6a3f 292 Pfam PF00296 Luciferase-like monooxygenase 1 231 1.5E-40 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_06130 1c90dddedb57fd1c8d4a320924ee6a3f 292 SUPERFAMILY SSF51679 1 289 1.24E-53 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_00290 afed1c64cd7e7867cb6dc26d48209899 488 SUPERFAMILY SSF51556 61 416 9.87E-58 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_00290 afed1c64cd7e7867cb6dc26d48209899 488 Gene3D G3DSA:3.20.20.140 60 455 6.5E-99 T 14-10-2018 A4R43_00290 afed1c64cd7e7867cb6dc26d48209899 488 Gene3D G3DSA:2.30.40.10 6 470 6.5E-99 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_00290 afed1c64cd7e7867cb6dc26d48209899 488 SUPERFAMILY SSF51338 5 485 4.98E-29 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_00290 afed1c64cd7e7867cb6dc26d48209899 488 Pfam PF01979 Amidohydrolase family 383 468 3.2E-11 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4R43_07100 ea54d6c51361be1fa526e2bb472854a0 203 Gene3D G3DSA:1.10.357.10 2 194 3.9E-31 T 14-10-2018 A4R43_07100 ea54d6c51361be1fa526e2bb472854a0 203 SUPERFAMILY SSF46689 2 75 1.15E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_07100 ea54d6c51361be1fa526e2bb472854a0 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 6.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07100 ea54d6c51361be1fa526e2bb472854a0 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 6.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_07100 ea54d6c51361be1fa526e2bb472854a0 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.8E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_28550 d9566ce470e5cfeeb1908b5d75972aa6 390 SUPERFAMILY SSF51182 6 385 1.62E-94 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_28550 d9566ce470e5cfeeb1908b5d75972aa6 390 Pfam PF04209 homogentisate 1,2-dioxygenase 10 383 2.0E-16 T 14-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 A4R43_28550 d9566ce470e5cfeeb1908b5d75972aa6 390 Gene3D G3DSA:2.60.120.10 266 363 1.3E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_28550 d9566ce470e5cfeeb1908b5d75972aa6 390 Gene3D G3DSA:2.60.120.10 82 173 7.6E-9 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_24810 9008b81b36984dd1ba7c206bf89a4c46 127 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 26 91 6.7E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_11865 2079d963a3a486187f8a3e5c96daca4e 274 SUPERFAMILY SSF141523 152 273 9.55E-19 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_11865 2079d963a3a486187f8a3e5c96daca4e 274 Pfam PF03734 L,D-transpeptidase catalytic domain 158 265 5.4E-12 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4R43_11865 2079d963a3a486187f8a3e5c96daca4e 274 Gene3D G3DSA:2.40.440.10 149 274 7.4E-19 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_17740 db36f547fc27dffaf0cb313fc15bb1fe 273 Gene3D G3DSA:3.40.50.300 9 237 1.1E-63 T 14-10-2018 A4R43_17740 db36f547fc27dffaf0cb313fc15bb1fe 273 Pfam PF00005 ABC transporter 30 168 9.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_17740 db36f547fc27dffaf0cb313fc15bb1fe 273 SUPERFAMILY SSF52540 12 235 2.87E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_17740 db36f547fc27dffaf0cb313fc15bb1fe 273 SMART SM00382 38 218 1.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_02360 5402ed3bd7dae4b93e7fda1b7e52c2ef 255 SUPERFAMILY SSF109854 85 237 1.54E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_02360 5402ed3bd7dae4b93e7fda1b7e52c2ef 255 Pfam PF12867 DinB superfamily 93 240 6.9E-11 T 14-10-2018 IPR024775 DinB-like domain A4R43_21200 7c94077bb612209a1c33ca3c538abaca 444 Pfam PF02447 GntP family permease 3 443 1.1E-70 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 Pfam PF00023 Ankyrin repeat 29 59 8.4E-5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 SUPERFAMILY SSF48403 3 190 5.81E-41 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 PRINTS PR01415 Ankyrin repeat signature 29 44 9.6E-7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 PRINTS PR01415 Ankyrin repeat signature 148 162 9.6E-7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 SMART SM00248 94 123 2100.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 SMART SM00248 127 161 3.5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 SMART SM00248 61 90 3200.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 SMART SM00248 28 57 0.033 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 Gene3D G3DSA:1.25.40.20 1 191 1.6E-46 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4R43_07645 79754ff06beeff337e9a126b5fe68cc9 193 Pfam PF12796 Ankyrin repeats (3 copies) 76 163 6.7E-9 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain A4R43_36385 a081d2993e67a25ea0623fedd6d66d03 998 Pfam PF05729 NACHT domain 273 431 1.9E-21 T 14-10-2018 IPR007111 NACHT nucleoside triphosphatase A4R43_36385 a081d2993e67a25ea0623fedd6d66d03 998 SUPERFAMILY SSF52540 267 404 3.34E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_36385 a081d2993e67a25ea0623fedd6d66d03 998 Gene3D G3DSA:3.80.10.10 764 982 2.5E-11 T 14-10-2018 IPR032675 Leucine-rich repeat domain superfamily A4R43_36385 a081d2993e67a25ea0623fedd6d66d03 998 SUPERFAMILY SSF52058 781 938 2.38E-9 T 14-10-2018 A4R43_36385 a081d2993e67a25ea0623fedd6d66d03 998 Gene3D G3DSA:3.40.50.300 200 401 1.3E-6 T 14-10-2018 A4R43_06365 fccb81f653a1317ae5cd21af54031aee 288 Pfam PF14100 Methane oxygenase PmoA 11 282 2.6E-70 T 14-10-2018 IPR029475 Methane oxygenase PmoA A4R43_37520 b9bca87acfc04d9667a5022505363e68 698 Gene3D G3DSA:3.10.620.30 382 526 4.3E-15 T 14-10-2018 A4R43_37520 b9bca87acfc04d9667a5022505363e68 698 Pfam PF01841 Transglutaminase-like superfamily 388 505 2.5E-19 T 14-10-2018 IPR002931 Transglutaminase-like A4R43_37520 b9bca87acfc04d9667a5022505363e68 698 SMART SM00460 436 507 1.4E-10 T 14-10-2018 IPR002931 Transglutaminase-like A4R43_37520 b9bca87acfc04d9667a5022505363e68 698 SUPERFAMILY SSF54001 380 510 6.05E-23 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_09720 0f736a6e774913b37bafa7ecb52744cc 232 Pfam PF08241 Methyltransferase domain 45 138 1.5E-23 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_09720 0f736a6e774913b37bafa7ecb52744cc 232 Gene3D G3DSA:3.40.50.150 3 210 3.3E-46 T 14-10-2018 A4R43_09720 0f736a6e774913b37bafa7ecb52744cc 232 SUPERFAMILY SSF53335 3 210 1.41E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_00895 52e69e5894d3a7a7a6370f38dc9d786c 683 Pfam PF01968 Hydantoinase/oxoprolinase 202 488 8.6E-93 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 A4R43_00895 52e69e5894d3a7a7a6370f38dc9d786c 683 SUPERFAMILY SSF53067 1 315 7.25E-7 T 14-10-2018 A4R43_00895 52e69e5894d3a7a7a6370f38dc9d786c 683 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 180 1.9E-50 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 A4R43_00195 494944019ddd98e97ec97711f978ea51 436 Gene3D G3DSA:3.40.190.10 32 433 1.1E-74 T 14-10-2018 A4R43_00195 494944019ddd98e97ec97711f978ea51 436 Pfam PF13416 Bacterial extracellular solute-binding protein 56 366 1.0E-33 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_00195 494944019ddd98e97ec97711f978ea51 436 SUPERFAMILY SSF53850 25 427 1.71E-74 T 14-10-2018 A4R43_26120 85816d560861113c7002a3261df0f3b7 103 Pfam PF11662 Protein of unknown function (DUF3263) 22 93 2.4E-36 T 14-10-2018 IPR021678 Protein of unknown function DUF3263 A4R43_04485 63a29694e4ac2575941b0f3a2612a39e 179 Gene3D G3DSA:1.10.357.10 1 169 3.2E-36 T 14-10-2018 A4R43_04485 63a29694e4ac2575941b0f3a2612a39e 179 SUPERFAMILY SSF46689 2 58 9.75E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_04485 63a29694e4ac2575941b0f3a2612a39e 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 45 2.8E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_01920 2b39551ef1e7542f05ef583e1398dd56 170 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 29 128 2.8E-18 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_01920 2b39551ef1e7542f05ef583e1398dd56 170 Gene3D G3DSA:2.30.110.10 24 128 1.6E-10 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_01920 2b39551ef1e7542f05ef583e1398dd56 170 Pfam PF04075 F420H(2)-dependent quinone reductase 30 95 2.0E-7 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_03365 d25b72fd1bf931fedc29d7e999e32b38 247 Pfam PF01061 ABC-2 type transporter 6 211 9.5E-25 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_03365 d25b72fd1bf931fedc29d7e999e32b38 247 PIRSF PIRSF006648 1 247 1.1E-60 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_41735 0bdf8054cfc67768c97625571a7d917e 340 PIRSF PIRSF015921 3 340 2.7E-77 T 14-10-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 A4R43_41735 0bdf8054cfc67768c97625571a7d917e 340 Pfam PF00487 Fatty acid desaturase 58 314 2.6E-40 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_10510 81cd8d07ccd8071feb3a1346ac541c42 640 Gene3D G3DSA:3.90.226.10 386 640 1.7E-62 T 14-10-2018 A4R43_10510 81cd8d07ccd8071feb3a1346ac541c42 640 SUPERFAMILY SSF52096 385 640 1.14E-65 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_10510 81cd8d07ccd8071feb3a1346ac541c42 640 Pfam PF00378 Enoyl-CoA hydratase/isomerase 393 639 4.0E-36 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_10510 81cd8d07ccd8071feb3a1346ac541c42 640 Gene3D G3DSA:3.30.1540.10 231 322 6.4E-129 T 14-10-2018 A4R43_10510 81cd8d07ccd8071feb3a1346ac541c42 640 Gene3D G3DSA:3.40.50.10540 4 378 6.4E-129 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_10510 81cd8d07ccd8071feb3a1346ac541c42 640 Pfam PF02515 CoA-transferase family III 5 371 1.0E-126 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4R43_10510 81cd8d07ccd8071feb3a1346ac541c42 640 SUPERFAMILY SSF89796 2 379 4.84E-131 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily A4R43_32775 4bf5f729261e65861344f00466533a6d 288 SUPERFAMILY SSF54427 204 286 7.02E-5 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_17500 13bd3139204a893b8bb16c2bccb9360a 243 SUPERFAMILY SSF140453 6 101 5.36E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_09960 616edc5ccf317648b659acdf40b32388 209 Pfam PF02293 AmiS/UreI family transporter 1 165 3.8E-59 T 14-10-2018 IPR003211 AmiS/UreI transporter GO:0016020 A4R43_09960 616edc5ccf317648b659acdf40b32388 209 Gene3D G3DSA:1.25.40.600 1 167 2.7E-47 T 14-10-2018 IPR038523 AmiS/UreI transporter superfamily A4R43_21180 4e99f44d265a9d9b72b36836878700a2 188 SUPERFAMILY SSF52540 9 187 6.57E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21180 4e99f44d265a9d9b72b36836878700a2 188 Pfam PF13671 AAA domain 14 141 1.3E-9 T 14-10-2018 A4R43_21180 4e99f44d265a9d9b72b36836878700a2 188 Gene3D G3DSA:3.40.50.300 6 188 1.2E-23 T 14-10-2018 A4R43_20840 801970cf699599da71c4f9f148ec6a1e 148 SMART SM00347 28 128 5.3E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20840 801970cf699599da71c4f9f148ec6a1e 148 Gene3D G3DSA:1.10.10.10 9 142 2.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20840 801970cf699599da71c4f9f148ec6a1e 148 Pfam PF12802 MarR family 36 92 1.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20840 801970cf699599da71c4f9f148ec6a1e 148 SUPERFAMILY SSF46785 16 140 3.61E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_38725 db5f6872cbca32489d091e8060472138 373 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 14 347 1.2E-13 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4R43_38725 db5f6872cbca32489d091e8060472138 373 SUPERFAMILY SSF51726 11 372 5.49E-72 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_38725 db5f6872cbca32489d091e8060472138 373 Gene3D G3DSA:3.20.20.210 4 373 5.6E-117 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4R43_27220 9cebdbe0f1d24568e02378f0fb66e78c 71 Pfam PF13783 Domain of unknown function (DUF4177) 24 62 5.5E-6 T 14-10-2018 IPR025234 Protein of unknown function DUF4177 A4R43_02885 d7d67d844c0194bbb4c863f25bd5efe5 93 Gene3D G3DSA:1.20.58.1000 4 93 1.4E-35 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily A4R43_02885 d7d67d844c0194bbb4c863f25bd5efe5 93 Pfam PF02583 Metal-sensitive transcriptional repressor 7 89 2.6E-32 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A4R43_39085 cf55376fca0d6716ed62aaacd5af663f 837 Pfam PF00246 Zinc carboxypeptidase 99 371 1.7E-24 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_39085 cf55376fca0d6716ed62aaacd5af663f 837 SMART SM00631 92 372 1.1E-7 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4R43_39085 cf55376fca0d6716ed62aaacd5af663f 837 SUPERFAMILY SSF53187 92 368 4.63E-42 T 14-10-2018 A4R43_12445 13b9dc1cde34f78f464c1fd8298906a9 130 Gene3D G3DSA:1.10.510.10 1 86 2.8E-7 T 14-10-2018 A4R43_12445 13b9dc1cde34f78f464c1fd8298906a9 130 SUPERFAMILY SSF56112 2 116 2.29E-6 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_15575 ebe0c440f2f6c681f353ffe5f8b51665 184 SUPERFAMILY SSF81301 7 139 8.66E-28 T 14-10-2018 A4R43_15575 ebe0c440f2f6c681f353ffe5f8b51665 184 Pfam PF14907 Uncharacterised nucleotidyltransferase 8 176 3.5E-9 T 14-10-2018 IPR039498 Uncharacterised nucleotidyltransferase A4R43_15575 ebe0c440f2f6c681f353ffe5f8b51665 184 Gene3D G3DSA:3.30.460.40 2 138 1.4E-13 T 14-10-2018 A4R43_13490 7b0c394ae47a4f01c22fadd1f2e9c495 311 Gene3D G3DSA:3.20.20.100 7 305 6.8E-42 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_13490 7b0c394ae47a4f01c22fadd1f2e9c495 311 SUPERFAMILY SSF51430 10 299 7.07E-43 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4R43_13490 7b0c394ae47a4f01c22fadd1f2e9c495 311 Pfam PF00248 Aldo/keto reductase family 15 295 1.1E-27 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4R43_11850 758af0f58e60db7a35d63ed33ff439c7 416 SUPERFAMILY SSF56112 139 321 1.08E-16 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_11850 758af0f58e60db7a35d63ed33ff439c7 416 Gene3D G3DSA:3.90.1200.10 193 355 1.0E-5 T 14-10-2018 A4R43_38305 b9f3a1d0cb7a31440e01064b82c4697d 180 Gene3D G3DSA:3.40.630.30 1 160 3.2E-45 T 14-10-2018 A4R43_38305 b9f3a1d0cb7a31440e01064b82c4697d 180 SUPERFAMILY SSF55729 1 148 2.74E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_38305 b9f3a1d0cb7a31440e01064b82c4697d 180 Pfam PF00583 Acetyltransferase (GNAT) family 36 134 2.2E-16 T 14-10-2018 IPR000182 GNAT domain A4R43_06885 488bd6b7fee3fb7b2a2acd259f02eaca 153 Pfam PF03780 Asp23 family, cell envelope-related function 30 138 1.5E-31 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 A4R43_28695 5a8185f9480175b30d55c9f851c34d27 136 Pfam PF15585 Immunity protein 7 1 129 1.8E-40 T 14-10-2018 IPR028965 Immunity protein 7 A4R43_09130 071b777e2d80ce095e64ceb57315025e 277 PIRSF PIRSF001359 1 276 4.5E-72 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_09130 071b777e2d80ce095e64ceb57315025e 277 Gene3D G3DSA:3.20.20.70 1 277 8.0E-90 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4R43_09130 071b777e2d80ce095e64ceb57315025e 277 SUPERFAMILY SSF51569 2 275 1.47E-81 T 14-10-2018 A4R43_09130 071b777e2d80ce095e64ceb57315025e 277 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 275 3.9E-84 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_09130 071b777e2d80ce095e64ceb57315025e 277 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 271 3.7E-68 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4R43_06910 878e2670a2e42dcd14497c58fb189c3a 166 Pfam PF00583 Acetyltransferase (GNAT) family 54 134 2.4E-13 T 14-10-2018 IPR000182 GNAT domain A4R43_06910 878e2670a2e42dcd14497c58fb189c3a 166 Gene3D G3DSA:3.40.630.30 5 148 1.1E-28 T 14-10-2018 A4R43_06910 878e2670a2e42dcd14497c58fb189c3a 166 SUPERFAMILY SSF55729 1 143 7.62E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_00235 7885378a5d0477e3662668680c2d414a 273 SUPERFAMILY SSF102198 15 270 1.83E-40 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_00235 7885378a5d0477e3662668680c2d414a 273 Gene3D G3DSA:3.50.30.50 7 273 6.4E-49 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_00235 7885378a5d0477e3662668680c2d414a 273 Pfam PF04199 Putative cyclase 19 206 8.0E-28 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A4R43_06545 0522282ac5d9233a284cbfbd23cd5261 304 SUPERFAMILY SSF51735 1 301 2.05E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_06545 0522282ac5d9233a284cbfbd23cd5261 304 Gene3D G3DSA:3.40.50.720 2 302 1.6E-53 T 14-10-2018 A4R43_06545 0522282ac5d9233a284cbfbd23cd5261 304 Pfam PF13460 NAD(P)H-binding 7 208 1.7E-18 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_11920 2531faa69701a5bee6d869c1cc062eaf 159 SUPERFAMILY SSF54427 44 156 3.55E-10 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_11920 2531faa69701a5bee6d869c1cc062eaf 159 Gene3D G3DSA:3.10.450.50 17 157 3.0E-7 T 14-10-2018 A4R43_05180 6491485619bebc24257d648207164a60 361 SUPERFAMILY SSF47240 24 332 4.06E-94 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_05180 6491485619bebc24257d648207164a60 361 PIRSF PIRSF000355 13 361 2.3E-127 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05180 6491485619bebc24257d648207164a60 361 Pfam PF00268 Ribonucleotide reductase, small chain 41 328 6.4E-84 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4R43_05180 6491485619bebc24257d648207164a60 361 Gene3D G3DSA:1.10.620.20 19 354 6.8E-106 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4R43_10520 5f64b29b478f5eef2aeeb1a1f9b3a511 437 Pfam PF03600 Citrate transporter 263 431 2.1E-8 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A4R43_10520 5f64b29b478f5eef2aeeb1a1f9b3a511 437 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 149 3.5E-55 T 14-10-2018 IPR009827 Dicarboxylate carrier MatC N-terminal A4R43_27940 2f8fbcacd006e42dff77432cbb479211 64 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 7 63 3.0E-24 T 14-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 A4R43_27940 2f8fbcacd006e42dff77432cbb479211 64 SUPERFAMILY SSF52777 15 62 2.89E-5 T 14-10-2018 A4R43_06185 d2456d21358a87fe0d274f9f364c0ad1 489 Pfam PF03055 Retinal pigment epithelial membrane protein 50 487 3.5E-94 T 14-10-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 A4R43_22660 e6b04ea6ad873c0563d447b1156477b0 378 SUPERFAMILY SSF56601 41 367 1.34E-74 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_22660 e6b04ea6ad873c0563d447b1156477b0 378 Gene3D G3DSA:3.40.710.10 26 377 2.6E-102 T 14-10-2018 A4R43_22660 e6b04ea6ad873c0563d447b1156477b0 378 Pfam PF00144 Beta-lactamase 49 366 4.7E-60 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_25845 e047a664aa23812acc846b9c48edcbc4 204 Gene3D G3DSA:1.10.150.240 16 80 1.1E-24 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4R43_25845 e047a664aa23812acc846b9c48edcbc4 204 SUPERFAMILY SSF56784 5 199 1.45E-34 T 14-10-2018 IPR036412 HAD-like superfamily A4R43_25845 e047a664aa23812acc846b9c48edcbc4 204 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 155 9.0E-12 T 14-10-2018 A4R43_25845 e047a664aa23812acc846b9c48edcbc4 204 Gene3D G3DSA:3.40.50.1000 6 190 1.1E-24 T 14-10-2018 IPR023214 HAD superfamily A4R43_12670 46d30c361d090f0fa73efd07f58f1a81 236 Pfam PF11139 Sap, sulfolipid-1-addressing protein 11 212 2.8E-20 T 14-10-2018 IPR021315 Glycolipid exporter Gap/Sap A4R43_09520 2dfc60901aec4faa4c357ff88468e664 156 Hamap MF_00775 UPF0311 protein . 6 156 23.392 T 14-10-2018 IPR020915 Uncharacterised protein family UPF0311 A4R43_09520 2dfc60901aec4faa4c357ff88468e664 156 Pfam PF11578 Protein of unknown function (DUF3237) 6 154 6.9E-39 T 14-10-2018 IPR020915 Uncharacterised protein family UPF0311 A4R43_09520 2dfc60901aec4faa4c357ff88468e664 156 Gene3D G3DSA:2.40.160.20 3 155 7.0E-48 T 14-10-2018 A4R43_34625 77eafdff5bba48c0de1ff0e2917a43c9 196 Gene3D G3DSA:3.40.430.10 2 191 4.4E-33 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_34625 77eafdff5bba48c0de1ff0e2917a43c9 196 Pfam PF01872 RibD C-terminal domain 102 187 1.3E-9 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_34625 77eafdff5bba48c0de1ff0e2917a43c9 196 SUPERFAMILY SSF53597 2 194 1.27E-25 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_29685 02d851aace91aa884355297548347238 129 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 3 46 8.7E-5 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal A4R43_09220 e075098503651d87637d99e84fd12d43 268 Pfam PF01695 IstB-like ATP binding protein 72 243 8.6E-61 T 14-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 A4R43_09220 e075098503651d87637d99e84fd12d43 268 SMART SM00382 111 244 4.8E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_09220 e075098503651d87637d99e84fd12d43 268 Gene3D G3DSA:3.40.50.300 74 257 1.2E-46 T 14-10-2018 A4R43_09220 e075098503651d87637d99e84fd12d43 268 SUPERFAMILY SSF52540 80 241 1.05E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09220 e075098503651d87637d99e84fd12d43 268 PIRSF PIRSF003073 13 260 2.0E-86 T 14-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein A4R43_23260 77004f402d44fe4eb2cf8f18bf8c446a 307 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 288 8.6E-41 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4R43_23260 77004f402d44fe4eb2cf8f18bf8c446a 307 Pfam PF01545 Cation efflux family 11 212 1.3E-32 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4R43_23260 77004f402d44fe4eb2cf8f18bf8c446a 307 Gene3D G3DSA:1.20.1510.10 7 217 7.6E-30 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4R43_23260 77004f402d44fe4eb2cf8f18bf8c446a 307 SUPERFAMILY SSF161111 6 219 3.01E-37 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4R43_18675 1e33722f20c432ad80eaa7ce9a0c8854 95 SUPERFAMILY SSF54975 7 93 3.49E-25 T 14-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4R43_18675 1e33722f20c432ad80eaa7ce9a0c8854 95 Gene3D G3DSA:3.30.70.100 5 94 6.0E-26 T 14-10-2018 A4R43_18675 1e33722f20c432ad80eaa7ce9a0c8854 95 Pfam PF00708 Acylphosphatase 11 92 1.1E-22 T 14-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4R43_18675 1e33722f20c432ad80eaa7ce9a0c8854 95 ProSitePatterns PS00150 Acylphosphatase signature 1. 14 24 - T 14-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4R43_08800 319dd3c4a44583cbcc99a063fdc31db3 163 Gene3D G3DSA:3.40.630.30 3 163 6.2E-24 T 14-10-2018 A4R43_08800 319dd3c4a44583cbcc99a063fdc31db3 163 Pfam PF13302 Acetyltransferase (GNAT) domain 6 138 8.1E-15 T 14-10-2018 IPR000182 GNAT domain A4R43_08800 319dd3c4a44583cbcc99a063fdc31db3 163 SUPERFAMILY SSF55729 5 161 3.48E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_03110 74339754833a60fcf73932197bce4666 144 Gene3D G3DSA:3.30.565.10 16 141 1.6E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03110 74339754833a60fcf73932197bce4666 144 SMART SM00387 44 144 3.9E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_03110 74339754833a60fcf73932197bce4666 144 SUPERFAMILY SSF55874 40 138 5.11E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_03110 74339754833a60fcf73932197bce4666 144 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 45 138 3.1E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_38780 a7b92a4df14a8ce3e36adb576d12dfe1 135 Pfam PF03995 Peptidase inhibitor family I36 46 111 1.1E-8 T 14-10-2018 A4R43_35505 71f8c5c0232a4e7805c268e51ded1c29 249 Pfam PF00583 Acetyltransferase (GNAT) family 146 228 2.1E-14 T 14-10-2018 IPR000182 GNAT domain A4R43_35505 71f8c5c0232a4e7805c268e51ded1c29 249 Gene3D G3DSA:3.40.630.30 11 239 1.2E-23 T 14-10-2018 A4R43_35505 71f8c5c0232a4e7805c268e51ded1c29 249 SUPERFAMILY SSF55729 118 237 4.29E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_19910 b3d91aabcf0ffc132a7e4f0f7a6231f7 222 Pfam PF10935 Protein of unknown function (DUF2637) 16 133 8.2E-15 T 14-10-2018 IPR021235 Protein of unknown function DUF2637 A4R43_24210 1bbd7ec2172bb2533881c7adafdc4032 179 Gene3D G3DSA:3.40.430.10 2 174 1.8E-38 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_24210 1bbd7ec2172bb2533881c7adafdc4032 179 SUPERFAMILY SSF53597 2 177 3.67E-27 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_24210 1bbd7ec2172bb2533881c7adafdc4032 179 Pfam PF01872 RibD C-terminal domain 2 168 2.3E-23 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_13610 3186706987f116cd4076ad229e5d5868 424 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 335 3.4E-107 T 14-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A4R43_13610 3186706987f116cd4076ad229e5d5868 424 SUPERFAMILY SSF51905 5 231 1.11E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_13610 3186706987f116cd4076ad229e5d5868 424 Gene3D G3DSA:3.50.50.60 2 414 1.4E-116 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_28160 776f36c59fdfdf78f3895c22abca4378 310 Gene3D G3DSA:1.10.357.140 38 181 5.5E-10 T 14-10-2018 A4R43_28160 776f36c59fdfdf78f3895c22abca4378 310 Pfam PF01040 UbiA prenyltransferase family 44 277 1.1E-18 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A4R43_24670 80d58dc84713ec63cc4be7f60e78fca6 201 Pfam PF04234 CopC domain 40 128 1.3E-16 T 14-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 A4R43_24670 80d58dc84713ec63cc4be7f60e78fca6 201 Gene3D G3DSA:2.60.40.1220 39 135 7.1E-14 T 14-10-2018 A4R43_24670 80d58dc84713ec63cc4be7f60e78fca6 201 SUPERFAMILY SSF81296 38 128 5.95E-16 T 14-10-2018 IPR014756 Immunoglobulin E-set A4R43_40895 11943aca411de14e20c1446f8e0ad5fd 449 Pfam PF00561 alpha/beta hydrolase fold 102 158 2.7E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_40895 11943aca411de14e20c1446f8e0ad5fd 449 SUPERFAMILY SSF53474 33 376 7.5E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_32500 694e6feb3ff821bc890a8fa979cd277c 111 PRINTS PR01217 Proline rich extensin signature 35 56 3.9E-11 T 14-10-2018 A4R43_32500 694e6feb3ff821bc890a8fa979cd277c 111 PRINTS PR01217 Proline rich extensin signature 57 73 3.9E-11 T 14-10-2018 A4R43_32500 694e6feb3ff821bc890a8fa979cd277c 111 PRINTS PR01217 Proline rich extensin signature 76 93 3.9E-11 T 14-10-2018 A4R43_32500 694e6feb3ff821bc890a8fa979cd277c 111 PRINTS PR01217 Proline rich extensin signature 19 31 3.9E-11 T 14-10-2018 A4R43_31330 254b3c2e56815e61bba0d604f3794e8d 390 Gene3D G3DSA:1.20.1250.20 7 203 1.4E-14 T 14-10-2018 A4R43_31330 254b3c2e56815e61bba0d604f3794e8d 390 Gene3D G3DSA:1.20.1250.20 219 390 3.7E-15 T 14-10-2018 A4R43_31330 254b3c2e56815e61bba0d604f3794e8d 390 SUPERFAMILY SSF103473 8 386 7.06E-36 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_31330 254b3c2e56815e61bba0d604f3794e8d 390 Pfam PF07690 Major Facilitator Superfamily 19 360 7.6E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_17735 ff2b238f671c22abeeab54270fdfbbe4 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 258 2.3E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_17735 ff2b238f671c22abeeab54270fdfbbe4 273 Gene3D G3DSA:1.10.3720.10 64 260 2.1E-27 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_17735 ff2b238f671c22abeeab54270fdfbbe4 273 SUPERFAMILY SSF161098 65 251 7.46E-33 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_36485 b4479d0d19d7262460b0f8c0e68cc6e1 90 Pfam PF04226 Transglycosylase associated protein 35 83 1.6E-14 T 14-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 A4R43_19020 d0f2b7b703024df4d28d45852ea087fc 305 SUPERFAMILY SSF63829 2 297 6.98E-43 T 14-10-2018 A4R43_19020 d0f2b7b703024df4d28d45852ea087fc 305 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 35 218 1.0E-15 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region A4R43_19020 d0f2b7b703024df4d28d45852ea087fc 305 Gene3D G3DSA:2.120.10.30 3 305 1.3E-59 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4R43_00695 f36f6eb5b15cf1433cc9794478ccc5c3 258 SUPERFAMILY SSF53474 15 256 1.86E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_00695 f36f6eb5b15cf1433cc9794478ccc5c3 258 Gene3D G3DSA:3.40.50.1820 7 257 2.4E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_28365 d5f4014cc9488ef1e69e30052c5e700c 150 Pfam PF03994 Domain of Unknown Function (DUF350) 25 78 4.0E-15 T 14-10-2018 IPR007140 Protein of unknown function DUF350 A4R43_28365 d5f4014cc9488ef1e69e30052c5e700c 150 Pfam PF03994 Domain of Unknown Function (DUF350) 95 148 9.6E-13 T 14-10-2018 IPR007140 Protein of unknown function DUF350 A4R43_12755 7003cc3230911cd53d3a67dcbf6fbabc 314 SUPERFAMILY SSF56601 29 293 2.94E-55 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_12755 7003cc3230911cd53d3a67dcbf6fbabc 314 Pfam PF00144 Beta-lactamase 25 291 1.8E-22 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_12755 7003cc3230911cd53d3a67dcbf6fbabc 314 Gene3D G3DSA:3.40.710.10 8 301 9.6E-50 T 14-10-2018 A4R43_03035 fe871600d8581a1ce74e31c442a7a730 301 Pfam PF12697 Alpha/beta hydrolase family 46 283 2.6E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_03035 fe871600d8581a1ce74e31c442a7a730 301 SUPERFAMILY SSF53474 16 294 5.82E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_03035 fe871600d8581a1ce74e31c442a7a730 301 Gene3D G3DSA:3.40.50.1820 23 294 2.0E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08110 c8948c14c76c7b3193d1f551e9dbd1c0 490 Gene3D G3DSA:1.20.1250.20 266 484 8.3E-13 T 14-10-2018 A4R43_08110 c8948c14c76c7b3193d1f551e9dbd1c0 490 Pfam PF07690 Major Facilitator Superfamily 24 410 3.2E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4R43_08110 c8948c14c76c7b3193d1f551e9dbd1c0 490 SUPERFAMILY SSF103473 7 485 5.49E-52 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_08110 c8948c14c76c7b3193d1f551e9dbd1c0 490 Gene3D G3DSA:1.20.1720.10 15 244 2.1E-36 T 14-10-2018 A4R43_10910 46a7b231e6434b3aa1a097f4424f09cf 652 Pfam PF07693 KAP family P-loop domain 205 286 2.8E-6 T 14-10-2018 IPR011646 KAP family P-loop domain A4R43_10910 46a7b231e6434b3aa1a097f4424f09cf 652 Pfam PF07693 KAP family P-loop domain 570 625 1.8E-10 T 14-10-2018 IPR011646 KAP family P-loop domain A4R43_10910 46a7b231e6434b3aa1a097f4424f09cf 652 SUPERFAMILY SSF52949 98 171 3.73E-6 T 14-10-2018 A4R43_10910 46a7b231e6434b3aa1a097f4424f09cf 652 Gene3D G3DSA:3.40.220.10 96 175 4.7E-7 T 14-10-2018 A4R43_25015 1b55995512cba99ec56eeadc42f1c8f1 200 SUPERFAMILY SSF53335 47 187 1.16E-14 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_25015 1b55995512cba99ec56eeadc42f1c8f1 200 Gene3D G3DSA:3.40.50.150 47 199 2.1E-14 T 14-10-2018 A4R43_31670 b758e34075f6ebb5cc66a2cd74c89de7 674 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 139 580 4.4E-57 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A4R43_31670 b758e34075f6ebb5cc66a2cd74c89de7 674 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 41 666 7.2E-123 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ A4R43_31840 2880184e36fe7d7438ea64c9624c4eb3 144 SUPERFAMILY SSF141523 38 142 3.4E-22 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_31840 2880184e36fe7d7438ea64c9624c4eb3 144 Pfam PF03734 L,D-transpeptidase catalytic domain 39 142 6.5E-17 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4R43_31840 2880184e36fe7d7438ea64c9624c4eb3 144 Gene3D G3DSA:2.40.440.10 36 144 1.3E-22 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A4R43_21925 277a79c2175e644d3f008016d5033d68 158 Gene3D G3DSA:3.40.50.450 5 156 5.5E-10 T 14-10-2018 A4R43_21925 277a79c2175e644d3f008016d5033d68 158 SUPERFAMILY SSF102405 1 155 2.11E-16 T 14-10-2018 A4R43_13295 4a29630aecc2d4217e8c352bf415ab7b 105 SUPERFAMILY SSF49503 23 94 2.03E-8 T 14-10-2018 IPR008972 Cupredoxin A4R43_13295 4a29630aecc2d4217e8c352bf415ab7b 105 Gene3D G3DSA:2.60.40.420 14 101 1.3E-7 T 14-10-2018 IPR008972 Cupredoxin A4R43_37250 c7001480ff67e061cf1982133aa31a54 485 SUPERFAMILY SSF51905 7 364 9.91E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_37250 c7001480ff67e061cf1982133aa31a54 485 Gene3D G3DSA:3.50.50.60 3 380 3.4E-18 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_04815 807352ac2ce27ace7cf7557197d29001 216 Gene3D G3DSA:2.40.30.20 1 88 3.7E-28 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_04815 807352ac2ce27ace7cf7557197d29001 216 PIRSF PIRSF000498 1 204 3.1E-70 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04815 807352ac2ce27ace7cf7557197d29001 216 SUPERFAMILY SSF63380 2 89 3.74E-25 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_04815 807352ac2ce27ace7cf7557197d29001 216 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 189 1.3E-60 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04815 807352ac2ce27ace7cf7557197d29001 216 Gene3D G3DSA:2.40.30.20 101 198 1.1E-32 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4R43_04815 807352ac2ce27ace7cf7557197d29001 216 Pfam PF00677 Lumazine binding domain 3 86 1.0E-23 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04815 807352ac2ce27ace7cf7557197d29001 216 Pfam PF00677 Lumazine binding domain 99 180 1.3E-23 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4R43_04815 807352ac2ce27ace7cf7557197d29001 216 SUPERFAMILY SSF63380 92 192 6.89E-29 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4R43_27245 9916d5279ecbfab830defe9185a2589e 104 Pfam PF02467 Transcription factor WhiB 8 70 1.7E-22 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain A4R43_27245 9916d5279ecbfab830defe9185a2589e 104 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 75 17.612 T 14-10-2018 IPR003482 Transcription factor WhiB A4R43_26445 5a51e9f33e136fed59662358683feb30 236 Pfam PF13490 Putative zinc-finger 3 37 1.8E-5 T 14-10-2018 IPR027383 Putative zinc-finger A4R43_30625 6f49f67d87069386a8c1cd32d24197b6 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.8E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_30625 6f49f67d87069386a8c1cd32d24197b6 246 SUPERFAMILY SSF46689 5 76 1.07E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_30625 6f49f67d87069386a8c1cd32d24197b6 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.0E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_30625 6f49f67d87069386a8c1cd32d24197b6 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.0E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_30625 6f49f67d87069386a8c1cd32d24197b6 246 Gene3D G3DSA:1.10.357.10 1 243 9.9E-60 T 14-10-2018 A4R43_30625 6f49f67d87069386a8c1cd32d24197b6 246 SUPERFAMILY SSF48498 89 239 1.51E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_39720 a26f5a9660bb3f19b9595f843cdb08fa 336 Pfam PF03773 Predicted permease 52 328 1.3E-46 T 14-10-2018 IPR005524 Predicted permease DUF318 A4R43_26890 719bcfe64af35a133495d34fde241d7a 286 Gene3D G3DSA:3.40.630.30 8 285 4.7E-24 T 14-10-2018 A4R43_26890 719bcfe64af35a133495d34fde241d7a 286 Pfam PF00583 Acetyltransferase (GNAT) family 190 273 3.2E-7 T 14-10-2018 IPR000182 GNAT domain A4R43_26890 719bcfe64af35a133495d34fde241d7a 286 SUPERFAMILY SSF55729 85 280 2.7E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_41020 e483504fd288f7de4429101e1bf6e7ed 164 Pfam PF03703 Bacterial PH domain 74 152 4.8E-17 T 14-10-2018 IPR005182 Domain of unknown function DUF304 A4R43_35090 4a0372cddecb542a6db9a13416178568 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 319 1.7E-25 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_27855 9e1af6eb01f2aa58aa242940e411f03c 369 Gene3D G3DSA:1.20.1260.20 53 206 6.5E-7 T 14-10-2018 IPR038332 PPE superfamily A4R43_27855 9e1af6eb01f2aa58aa242940e411f03c 369 SUPERFAMILY SSF140459 57 204 1.8E-5 T 14-10-2018 A4R43_00280 c4e5eb19d3fcd631477b7564cddc78dc 212 Gene3D G3DSA:3.40.50.12500 14 210 1.3E-15 T 14-10-2018 A4R43_29005 9297ae0ddbbf3ca5a644f6a465f36328 409 Pfam PF05977 Transmembrane secretion effector 8 389 1.0E-38 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_29005 9297ae0ddbbf3ca5a644f6a465f36328 409 Gene3D G3DSA:1.20.1250.20 8 389 7.3E-39 T 14-10-2018 A4R43_29005 9297ae0ddbbf3ca5a644f6a465f36328 409 SUPERFAMILY SSF103473 11 392 6.8E-47 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_07665 feae975f17394483daac80d31a27af2d 393 Pfam PF07969 Amidohydrolase family 131 386 2.6E-24 T 14-10-2018 IPR013108 Amidohydrolase 3 A4R43_07665 feae975f17394483daac80d31a27af2d 393 SUPERFAMILY SSF51338 2 392 2.28E-12 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_07665 feae975f17394483daac80d31a27af2d 393 Gene3D G3DSA:2.30.40.10 3 386 7.7E-110 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4R43_07665 feae975f17394483daac80d31a27af2d 393 SUPERFAMILY SSF51556 50 357 5.3E-73 T 14-10-2018 IPR032466 Metal-dependent hydrolase A4R43_07665 feae975f17394483daac80d31a27af2d 393 Gene3D G3DSA:3.20.20.140 51 347 7.7E-110 T 14-10-2018 A4R43_01435 0fd3237b4f96271468f223a1f87e2440 397 SUPERFAMILY SSF140459 29 152 3.14E-5 T 14-10-2018 A4R43_05310 0bf16c5d5e96e70069a9a3d112325a2c 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 265 2.7E-48 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_05310 0bf16c5d5e96e70069a9a3d112325a2c 272 Gene3D G3DSA:1.10.12.10 211 266 4.1E-6 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A4R43_05310 0bf16c5d5e96e70069a9a3d112325a2c 272 SUPERFAMILY SSF52096 10 267 4.64E-72 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_05310 0bf16c5d5e96e70069a9a3d112325a2c 272 Gene3D G3DSA:3.90.226.10 3 209 6.0E-63 T 14-10-2018 A4R43_09055 5904c9bbf544947282c5f5ae6b043ab5 330 SUPERFAMILY SSF101898 103 328 7.59E-18 T 14-10-2018 A4R43_09055 5904c9bbf544947282c5f5ae6b043ab5 330 Gene3D G3DSA:2.130.10.10 172 327 3.7E-10 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_30270 dc4fada0c3308150f6bdcb9c9ed2e722 194 Gene3D G3DSA:1.10.10.60 10 70 2.1E-5 T 14-10-2018 A4R43_14975 dc4fada0c3308150f6bdcb9c9ed2e722 194 Gene3D G3DSA:1.10.10.60 10 70 2.1E-5 T 14-10-2018 A4R43_29895 dc4fada0c3308150f6bdcb9c9ed2e722 194 Gene3D G3DSA:1.10.10.60 10 70 2.1E-5 T 14-10-2018 A4R43_20805 c43a5a59d9550a7f0940d601ab74d476 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 27 120 2.0E-29 T 14-10-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4R43_20805 c43a5a59d9550a7f0940d601ab74d476 137 Gene3D G3DSA:2.30.31.20 3 134 7.7E-40 T 14-10-2018 IPR038658 Sporulation-specific cell division protein SsgB superfamily A4R43_11165 46c79a0a55c6e92e9bb5c27cce3d7d9e 250 Pfam PF14011 EspG family 9 239 5.1E-46 T 14-10-2018 IPR025734 EspG family A4R43_31495 b1fbc9ab2a901dde7332e8527fd4095b 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 319 6.3E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_40325 faf9659cee902147898441b91a2d1b91 202 Gene3D G3DSA:1.10.10.60 4 62 1.8E-16 T 14-10-2018 A4R43_40325 faf9659cee902147898441b91a2d1b91 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 9.4E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40325 faf9659cee902147898441b91a2d1b91 202 SUPERFAMILY SSF48498 85 200 1.53E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_40325 faf9659cee902147898441b91a2d1b91 202 SUPERFAMILY SSF46689 13 81 1.36E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_40325 faf9659cee902147898441b91a2d1b91 202 Gene3D G3DSA:1.10.357.10 63 202 3.7E-10 T 14-10-2018 A4R43_40325 faf9659cee902147898441b91a2d1b91 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40325 faf9659cee902147898441b91a2d1b91 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03070 83e9c9e91af22c999c6016ca479c6737 200 SUPERFAMILY SSF48498 74 194 1.87E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_03070 83e9c9e91af22c999c6016ca479c6737 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 50 2.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_03070 83e9c9e91af22c999c6016ca479c6737 200 Gene3D G3DSA:1.10.357.10 2 195 2.0E-29 T 14-10-2018 A4R43_03070 83e9c9e91af22c999c6016ca479c6737 200 SUPERFAMILY SSF46689 5 74 8.21E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_14715 5d1693d7726bf70fb98c6a99fe938ef2 303 SMART SM00382 28 214 2.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_14715 5d1693d7726bf70fb98c6a99fe938ef2 303 Pfam PF00005 ABC transporter 20 157 2.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_14715 5d1693d7726bf70fb98c6a99fe938ef2 303 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_14715 5d1693d7726bf70fb98c6a99fe938ef2 303 SUPERFAMILY SSF52540 2 221 3.12E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14715 5d1693d7726bf70fb98c6a99fe938ef2 303 Gene3D G3DSA:3.40.50.300 1 227 1.5E-67 T 14-10-2018 A4R43_23470 8ebf64bffc936342acc8a4ebeb856445 315 Pfam PF02646 RmuC family 48 275 3.7E-39 T 14-10-2018 IPR003798 DNA recombination RmuC A4R43_38010 54e1425dd20b10648d6b6a536df84b05 401 SUPERFAMILY SSF51905 2 366 6.39E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38010 54e1425dd20b10648d6b6a536df84b05 401 Gene3D G3DSA:3.50.50.60 5 345 1.1E-74 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4R43_38010 54e1425dd20b10648d6b6a536df84b05 401 Gene3D G3DSA:3.30.9.30 36 274 1.1E-74 T 14-10-2018 A4R43_38010 54e1425dd20b10648d6b6a536df84b05 401 Pfam PF01494 FAD binding domain 2 343 1.1E-25 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 A4R43_38010 54e1425dd20b10648d6b6a536df84b05 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 4.8E-19 T 14-10-2018 A4R43_38010 54e1425dd20b10648d6b6a536df84b05 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 4.8E-19 T 14-10-2018 A4R43_38010 54e1425dd20b10648d6b6a536df84b05 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 4.8E-19 T 14-10-2018 A4R43_38010 54e1425dd20b10648d6b6a536df84b05 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 4.8E-19 T 14-10-2018 A4R43_01620 56539cd13476e6ca0d2359936299840f 240 Gene3D G3DSA:3.40.50.1820 2 237 1.2E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01620 56539cd13476e6ca0d2359936299840f 240 SUPERFAMILY SSF53474 4 234 1.79E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01620 56539cd13476e6ca0d2359936299840f 240 Pfam PF00975 Thioesterase domain 5 232 2.6E-22 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4R43_07980 e3df6c99b617707a1b4611f9d953f654 285 Pfam PF13359 DDE superfamily endonuclease 131 278 3.5E-23 T 14-10-2018 IPR027806 Harbinger transposase-derived nuclease domain A4R43_29965 6429a30deb76855059c2be74505edac6 593 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 8 360 6.5E-135 T 14-10-2018 IPR010839 Acyclic terpene utilisation A4R43_01305 67823662b53b76e27319cfffd8fee754 490 SUPERFAMILY SSF53041 6 156 2.62E-20 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4R43_01305 67823662b53b76e27319cfffd8fee754 490 SMART SM00857 5 156 4.2E-30 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4R43_01305 67823662b53b76e27319cfffd8fee754 490 Pfam PF00239 Resolvase, N terminal domain 7 155 2.9E-19 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4R43_01305 67823662b53b76e27319cfffd8fee754 490 Gene3D G3DSA:3.40.50.1390 3 162 2.4E-29 T 14-10-2018 A4R43_01305 67823662b53b76e27319cfffd8fee754 490 Pfam PF07508 Recombinase 188 276 6.2E-13 T 14-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A4R43_29480 41d08369f05bb369f211d8ae459e9ba9 183 Gene3D G3DSA:3.90.79.10 9 142 1.1E-16 T 14-10-2018 A4R43_29480 41d08369f05bb369f211d8ae459e9ba9 183 Pfam PF00293 NUDIX domain 19 135 6.1E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4R43_29480 41d08369f05bb369f211d8ae459e9ba9 183 SUPERFAMILY SSF55811 19 134 2.44E-17 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_16330 65cb3af3292e43f17b91c4232ba98d42 166 Hamap MF_00977 3'-5' exoribonuclease. 1 159 43.242 T 14-10-2018 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 A4R43_16330 65cb3af3292e43f17b91c4232ba98d42 166 Pfam PF16473 3' exoribonuclease, RNase T-like 2 155 4.1E-18 T 14-10-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain A4R43_16330 65cb3af3292e43f17b91c4232ba98d42 166 SUPERFAMILY SSF53098 4 154 2.78E-5 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_16330 65cb3af3292e43f17b91c4232ba98d42 166 Gene3D G3DSA:3.30.420.10 1 163 6.9E-64 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4R43_17525 b884341e8d47598c6ba703294a0a46d0 437 Gene3D G3DSA:1.10.287.1060 27 110 1.8E-6 T 14-10-2018 A4R43_17525 b884341e8d47598c6ba703294a0a46d0 437 SUPERFAMILY SSF140459 10 112 9.15E-7 T 14-10-2018 A4R43_17645 795ead925c928b191ca5b62e4b175e81 204 SUPERFAMILY SSF109854 5 151 1.03E-8 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_17645 795ead925c928b191ca5b62e4b175e81 204 Gene3D G3DSA:1.20.120.450 4 149 1.7E-5 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_03400 6e44d1fc4f2bd2754376f5cc05dd9521 476 SUPERFAMILY SSF48371 85 395 9.12E-5 T 14-10-2018 IPR016024 Armadillo-type fold A4R43_29135 d541e5a5b3fc9d0f470113805b2c6c25 292 Pfam PF04203 Sortase family 101 271 3.9E-26 T 14-10-2018 IPR005754 Sortase family A4R43_29135 d541e5a5b3fc9d0f470113805b2c6c25 292 SUPERFAMILY SSF63817 71 272 3.77E-25 T 14-10-2018 IPR023365 Sortase domain superfamily A4R43_23215 c2a2c481b22628744f658de5a46ee6a7 218 Gene3D G3DSA:3.40.50.2020 36 217 1.0E-11 T 14-10-2018 A4R43_23215 c2a2c481b22628744f658de5a46ee6a7 218 SUPERFAMILY SSF53271 36 211 8.66E-14 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like A4R43_36720 869ea27e30403aad1b6a486f5e0651c9 1014 Gene3D G3DSA:2.60.40.10 589 681 1.0E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold A4R43_25385 35c73f561d69b8b11d1fe55babbe1ffd 149 Gene3D G3DSA:3.40.630.30 1 146 4.7E-32 T 14-10-2018 A4R43_25385 35c73f561d69b8b11d1fe55babbe1ffd 149 SUPERFAMILY SSF55729 2 143 2.48E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_25385 35c73f561d69b8b11d1fe55babbe1ffd 149 Pfam PF00583 Acetyltransferase (GNAT) family 59 131 3.6E-11 T 14-10-2018 IPR000182 GNAT domain A4R43_23155 01a24f50eb99ff51f0570b4a1cde69c9 202 SUPERFAMILY SSF53474 2 199 2.93E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_23155 01a24f50eb99ff51f0570b4a1cde69c9 202 Gene3D G3DSA:3.40.50.1820 22 197 6.9E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08905 885fdda3f876375bfc424bb1709a26d8 142 Gene3D G3DSA:2.40.50.140 81 141 4.5E-19 T 14-10-2018 A4R43_08905 885fdda3f876375bfc424bb1709a26d8 142 SUPERFAMILY SSF141322 76 139 1.27E-5 T 14-10-2018 A4R43_08905 885fdda3f876375bfc424bb1709a26d8 142 Pfam PF01957 NfeD-like C-terminal, partner-binding 5 139 2.1E-20 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain A4R43_08165 cb761f97002a39160c9b4c5e820e7e97 354 Pfam PF06224 Winged helix DNA-binding domain 32 351 2.5E-69 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 A4R43_04905 bc749432f707c301302bf9f8741637eb 214 PIRSF PIRSF006324 1 212 5.5E-52 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_04905 bc749432f707c301302bf9f8741637eb 214 Pfam PF01810 LysE type translocator 17 210 4.1E-28 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_31010 c4203d28993fe8fa1d2391211917f0ae 196 Pfam PF14436 Bacterial EndoU nuclease 9 76 2.4E-9 T 14-10-2018 IPR029501 Bacterial EndoU nuclease A4R43_23365 3e53e781186c0683efa825dcb0202c6c 99 Pfam PF03795 YCII-related domain 1 82 7.7E-8 T 14-10-2018 IPR005545 YCII-related A4R43_23365 3e53e781186c0683efa825dcb0202c6c 99 SUPERFAMILY SSF54909 1 82 4.29E-11 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_28915 f895767856a9dc7468081eec0baac303 295 Pfam PF01636 Phosphotransferase enzyme family 38 239 2.8E-18 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_28915 f895767856a9dc7468081eec0baac303 295 Gene3D G3DSA:3.90.1200.10 105 246 2.6E-8 T 14-10-2018 A4R43_28915 f895767856a9dc7468081eec0baac303 295 SUPERFAMILY SSF56112 5 260 1.21E-37 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_21220 214963b0d4cbe383c7d44afbaaf17181 111 SUPERFAMILY SSF54909 6 67 2.55E-9 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel A4R43_21220 214963b0d4cbe383c7d44afbaaf17181 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 6 67 4.8E-6 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4R43_31120 45d0aaaedc5641d2c20aa4a995a9d3b4 452 Gene3D G3DSA:2.160.20.100 220 376 4.4E-11 T 14-10-2018 A4R43_31120 45d0aaaedc5641d2c20aa4a995a9d3b4 452 SUPERFAMILY SSF141571 229 361 2.35E-6 T 14-10-2018 A4R43_34370 29e4ef0b0c65dcccdea21f3db6f14978 482 Gene3D G3DSA:3.40.605.10 33 464 7.8E-145 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4R43_34370 29e4ef0b0c65dcccdea21f3db6f14978 482 Pfam PF00171 Aldehyde dehydrogenase family 23 473 9.1E-136 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4R43_34370 29e4ef0b0c65dcccdea21f3db6f14978 482 SUPERFAMILY SSF53720 11 476 5.76E-134 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4R43_34370 29e4ef0b0c65dcccdea21f3db6f14978 482 Gene3D G3DSA:3.40.309.10 256 445 7.8E-145 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4R43_34370 29e4ef0b0c65dcccdea21f3db6f14978 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4R43_14575 ead9ae8bffe42ab13a82968aca608024 261 Pfam PF03649 Uncharacterised protein family (UPF0014) 29 254 3.2E-52 T 14-10-2018 IPR005226 UPF0014 family A4R43_34220 d081c38c2502ed6479fc17e475fbb057 315 Pfam PF05448 Acetyl xylan esterase (AXE1) 4 310 2.2E-100 T 14-10-2018 IPR008391 Acetyl xylan esterase A4R43_34220 d081c38c2502ed6479fc17e475fbb057 315 SUPERFAMILY SSF53474 6 301 3.21E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_34220 d081c38c2502ed6479fc17e475fbb057 315 Gene3D G3DSA:3.40.50.1820 5 314 3.7E-76 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_26135 5676a53f9e6e78a16d087563f2eb42dc 203 Pfam PF01810 LysE type translocator 15 199 1.7E-39 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_26135 5676a53f9e6e78a16d087563f2eb42dc 203 PIRSF PIRSF006324 1 202 8.9E-49 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_10050 7cdbc1ebc14248b856a317fa937584e7 593 SUPERFAMILY SSF81853 41 410 1.57E-53 T 14-10-2018 A4R43_10050 7cdbc1ebc14248b856a317fa937584e7 593 Pfam PF09492 Pectic acid lyase 166 384 4.2E-12 T 14-10-2018 IPR012669 Pectic acid lyase A4R43_10050 7cdbc1ebc14248b856a317fa937584e7 593 Gene3D G3DSA:1.50.10.20 76 440 2.4E-66 T 14-10-2018 A4R43_12680 5ff33da8f9fb6d9ff9f1cddb8b067ef3 271 PIRSF PIRSF006648 2 271 8.3E-68 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_12680 5ff33da8f9fb6d9ff9f1cddb8b067ef3 271 Pfam PF01061 ABC-2 type transporter 21 226 5.0E-25 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_06875 9806f43dce1c0267ad6eff76dc945cd7 123 Pfam PF03780 Asp23 family, cell envelope-related function 4 117 5.4E-17 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 A4R43_01110 8b97b9a97b70894ebf3a48cbca8a1099 222 Gene3D G3DSA:3.40.50.620 1 182 8.8E-8 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_01110 8b97b9a97b70894ebf3a48cbca8a1099 222 SUPERFAMILY SSF52402 1 178 7.54E-11 T 14-10-2018 A4R43_33810 cf023e789b105d114380e6cf1f96f2a0 282 Pfam PF01261 Xylose isomerase-like TIM barrel 69 233 1.1E-12 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_33810 cf023e789b105d114380e6cf1f96f2a0 282 SUPERFAMILY SSF51658 48 280 3.8E-37 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_33810 cf023e789b105d114380e6cf1f96f2a0 282 Gene3D G3DSA:3.20.20.150 40 282 2.1E-66 T 14-10-2018 A4R43_12470 ef9321bde560c45121b1184125346742 316 Pfam PF00892 EamA-like transporter family 17 145 3.4E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_12470 ef9321bde560c45121b1184125346742 316 Pfam PF00892 EamA-like transporter family 158 293 1.8E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4R43_12470 ef9321bde560c45121b1184125346742 316 SUPERFAMILY SSF103481 198 297 1.44E-17 T 14-10-2018 A4R43_12470 ef9321bde560c45121b1184125346742 316 SUPERFAMILY SSF103481 47 149 3.73E-10 T 14-10-2018 A4R43_40850 54117bdaeae1f546c34d87c1e8b40ecb 189 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 79 185 2.2E-9 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A4R43_40850 54117bdaeae1f546c34d87c1e8b40ecb 189 SUPERFAMILY SSF46689 2 73 3.84E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_40850 54117bdaeae1f546c34d87c1e8b40ecb 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 54 1.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_40850 54117bdaeae1f546c34d87c1e8b40ecb 189 Gene3D G3DSA:1.10.357.10 2 189 5.3E-39 T 14-10-2018 A4R43_40850 54117bdaeae1f546c34d87c1e8b40ecb 189 SUPERFAMILY SSF48498 77 186 4.3E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_22305 d7f0c37c8b6577766b64fa760b0f2ab7 217 Gene3D G3DSA:3.40.50.300 2 209 1.8E-27 T 14-10-2018 A4R43_22305 d7f0c37c8b6577766b64fa760b0f2ab7 217 SUPERFAMILY SSF52540 20 157 2.09E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_37545 d364ab39f6c9192b2c9050fec1e24b59 242 Pfam PF11209 Protein of unknown function (DUF2993) 64 215 2.6E-7 T 14-10-2018 IPR021373 Protein of unknown function DUF2993 A4R43_31290 6ae9ef4afd92fc6f476da72d8cc4b55e 193 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 34.632 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A4R43_31290 6ae9ef4afd92fc6f476da72d8cc4b55e 193 Pfam PF00692 dUTPase 71 176 4.4E-10 T 14-10-2018 IPR029054 dUTPase-like A4R43_31290 6ae9ef4afd92fc6f476da72d8cc4b55e 193 Gene3D G3DSA:2.70.40.10 1 186 2.4E-59 T 14-10-2018 IPR036157 dUTPase-like superfamily A4R43_31290 6ae9ef4afd92fc6f476da72d8cc4b55e 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 3.3E-64 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A4R43_31290 6ae9ef4afd92fc6f476da72d8cc4b55e 193 SUPERFAMILY SSF51283 2 184 9.95E-56 T 14-10-2018 IPR036157 dUTPase-like superfamily A4R43_35925 9c68f3e3970101c40955ffff3d268b8d 363 Pfam PF06224 Winged helix DNA-binding domain 53 351 9.7E-36 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 A4R43_41470 c9fbe8b98aec2a418db48c97ee101a1d 166 Gene3D G3DSA:2.30.110.10 10 149 5.9E-14 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_41470 c9fbe8b98aec2a418db48c97ee101a1d 166 SUPERFAMILY SSF50475 14 144 3.34E-13 T 14-10-2018 A4R43_29620 c0970aae4242ff96780d1372bf0c244f 317 SUPERFAMILY SSF48452 61 260 3.4E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_29620 c0970aae4242ff96780d1372bf0c244f 317 Gene3D G3DSA:1.25.40.10 58 315 1.3E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_12820 7a9ae4c0420e8215d1ea67c22ba1da63 178 Pfam PF13564 DoxX-like family 17 114 7.5E-14 T 14-10-2018 IPR032808 DoxX family A4R43_08025 5a66e2e48144f65ad41c622ed2442829 369 SUPERFAMILY SSF55874 248 364 7.46E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_08025 5a66e2e48144f65ad41c622ed2442829 369 Gene3D G3DSA:3.30.565.10 244 365 5.8E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_08025 5a66e2e48144f65ad41c622ed2442829 369 Pfam PF07730 Histidine kinase 165 230 1.1E-16 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4R43_08025 5a66e2e48144f65ad41c622ed2442829 369 SMART SM00387 279 367 4.9E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4R43_22285 718108939b5dc9de75b4b368d5895b25 310 SUPERFAMILY SSF69318 29 287 4.19E-10 T 14-10-2018 A4R43_15960 152e471e074b0bf3528d32516d895744 238 SUPERFAMILY SSF100950 3 234 3.43E-46 T 14-10-2018 IPR037171 NagB/RpiA transferase-like A4R43_15960 152e471e074b0bf3528d32516d895744 238 Gene3D G3DSA:3.40.1080.10 3 231 4.4E-41 T 14-10-2018 A4R43_15960 152e471e074b0bf3528d32516d895744 238 SMART SM00882 7 198 8.2E-4 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A4R43_36005 d025d6a23abfc4839f2f4b9892bc1ae0 335 Pfam PF01944 Stage II sporulation protein M 111 283 1.3E-33 T 14-10-2018 IPR002798 Stage II sporulation protein M-like A4R43_04770 ab15992a1c988025383291d486bbf6bd 708 Hamap MF_00983 Probable primosomal protein N' [priA]. 64 707 19.811 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A4R43_04770 ab15992a1c988025383291d486bbf6bd 708 Gene3D G3DSA:3.40.50.300 200 364 9.0E-26 T 14-10-2018 A4R43_04770 ab15992a1c988025383291d486bbf6bd 708 SUPERFAMILY SSF52540 223 300 8.86E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_04770 ab15992a1c988025383291d486bbf6bd 708 Gene3D G3DSA:1.10.8.630 57 168 6.2E-17 T 14-10-2018 A4R43_40705 13f19e0a1c26572813c4ab4f1e65192f 311 Pfam PF01636 Phosphotransferase enzyme family 63 252 1.4E-12 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase A4R43_40705 13f19e0a1c26572813c4ab4f1e65192f 311 SUPERFAMILY SSF56112 29 288 8.89E-23 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_14955 1cbdd9234716be44bcad28ae81ad4040 596 Pfam PF12846 AAA-like domain 231 548 3.3E-12 T 14-10-2018 A4R43_14955 1cbdd9234716be44bcad28ae81ad4040 596 SUPERFAMILY SSF52540 190 558 2.62E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_14955 1cbdd9234716be44bcad28ae81ad4040 596 Gene3D G3DSA:1.10.8.730 313 417 3.1E-77 T 14-10-2018 A4R43_14955 1cbdd9234716be44bcad28ae81ad4040 596 Gene3D G3DSA:3.40.50.300 222 559 3.1E-77 T 14-10-2018 A4R43_19045 8c15431be035566d50384f3e95a6515f 539 Gene3D G3DSA:3.30.300.310 444 539 1.4E-31 T 14-10-2018 A4R43_19045 8c15431be035566d50384f3e95a6515f 539 Pfam PF00501 AMP-binding enzyme 58 448 2.9E-64 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4R43_19045 8c15431be035566d50384f3e95a6515f 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 14-10-2018 IPR020845 AMP-binding, conserved site A4R43_19045 8c15431be035566d50384f3e95a6515f 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 532 8.0E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4R43_19045 8c15431be035566d50384f3e95a6515f 539 Gene3D G3DSA:3.40.50.12780 50 439 2.2E-80 T 14-10-2018 A4R43_19045 8c15431be035566d50384f3e95a6515f 539 SUPERFAMILY SSF56801 57 539 3.14E-116 T 14-10-2018 A4R43_04470 8a1c248143211dce79a0c54fae38af2f 313 Pfam PF04087 Domain of unknown function (DUF389) 145 288 1.8E-27 T 14-10-2018 IPR005240 Protein of unknown function DUF389 A4R43_14780 4cf70ca6dd218a34e23afa56881c859b 347 Pfam PF13489 Methyltransferase domain 114 260 1.3E-20 T 14-10-2018 A4R43_14780 4cf70ca6dd218a34e23afa56881c859b 347 SUPERFAMILY SSF53335 79 282 1.47E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_14780 4cf70ca6dd218a34e23afa56881c859b 347 Gene3D G3DSA:3.40.50.150 81 271 4.9E-24 T 14-10-2018 A4R43_09015 4df233794a0141eb8772614fa7fc934c 699 Pfam PF13515 Fusaric acid resistance protein-like 380 505 1.6E-12 T 14-10-2018 A4R43_38895 a0f3c89dbc4f1fad837354ce92ff6785 275 Pfam PF02517 CAAX protease self-immunity 131 223 1.3E-12 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A4R43_08835 599924b4847ade7d99e461e5737b1f74 184 Gene3D G3DSA:1.10.10.10 1 99 7.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_08835 599924b4847ade7d99e461e5737b1f74 184 SUPERFAMILY SSF46785 5 179 1.49E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08835 599924b4847ade7d99e461e5737b1f74 184 Pfam PF03551 Transcriptional regulator PadR-like family 9 85 2.7E-14 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4R43_29040 069c91cf88cd46075d529881e3ac819c 315 SUPERFAMILY SSF161098 89 298 1.03E-17 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_29040 069c91cf88cd46075d529881e3ac819c 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 6.8E-31 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_29040 069c91cf88cd46075d529881e3ac819c 315 Gene3D G3DSA:1.10.3720.10 89 308 6.8E-20 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_27775 9c6245513a962bce3ba36a46e4e485be 143 Gene3D G3DSA:3.30.530.20 2 143 6.8E-13 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_27775 9c6245513a962bce3ba36a46e4e485be 143 SUPERFAMILY SSF55961 3 142 8.94E-20 T 14-10-2018 A4R43_27775 9c6245513a962bce3ba36a46e4e485be 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 141 1.6E-18 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_08720 c9faa897c5f21f07f96acd71e90dcfe7 188 SUPERFAMILY SSF56645 18 152 4.65E-22 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4R43_08720 c9faa897c5f21f07f96acd71e90dcfe7 188 Gene3D G3DSA:1.10.540.10 6 115 1.1E-21 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4R43_08720 c9faa897c5f21f07f96acd71e90dcfe7 188 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 118 2.8E-7 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A4R43_19175 a4a0c1b9441b3c14f54b88356c416eba 239 SUPERFAMILY SSF52317 38 235 3.28E-37 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_19175 a4a0c1b9441b3c14f54b88356c416eba 239 Gene3D G3DSA:3.40.50.880 9 239 8.1E-68 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_19175 a4a0c1b9441b3c14f54b88356c416eba 239 Pfam PF07722 Peptidase C26 12 220 6.7E-60 T 14-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A4R43_37745 13a7b62b780a53085fdea04022bef507 322 SUPERFAMILY SSF53474 11 297 1.69E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_37745 13a7b62b780a53085fdea04022bef507 322 Gene3D G3DSA:3.40.50.1820 6 317 6.8E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_18860 b68ce3a0a39a0efd3d0da5f5a847943b 330 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 291 2.6E-56 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_18860 b68ce3a0a39a0efd3d0da5f5a847943b 330 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 3.0E-12 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_18860 b68ce3a0a39a0efd3d0da5f5a847943b 330 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 297 316 3.0E-12 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_18860 b68ce3a0a39a0efd3d0da5f5a847943b 330 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 3.0E-12 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_18860 b68ce3a0a39a0efd3d0da5f5a847943b 330 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 3.0E-12 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_18860 b68ce3a0a39a0efd3d0da5f5a847943b 330 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 3.0E-12 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_18860 b68ce3a0a39a0efd3d0da5f5a847943b 330 Pfam PF02470 MlaD protein 39 112 3.3E-14 T 14-10-2018 IPR003399 Mce/MlaD A4R43_36960 166f7eae9494c4573e3a7ad26289cf1e 287 SUPERFAMILY SSF53335 29 230 2.02E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_36960 166f7eae9494c4573e3a7ad26289cf1e 287 Gene3D G3DSA:3.40.50.150 9 272 1.8E-62 T 14-10-2018 A4R43_10580 ca4c017d1a2586701a8b0b6eb4bd31a3 163 Gene3D G3DSA:3.10.180.10 30 159 4.3E-6 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_10580 ca4c017d1a2586701a8b0b6eb4bd31a3 163 SUPERFAMILY SSF54593 30 137 1.69E-9 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_11835 b9578ee56d30b28cbda6246503329d41 201 Gene3D G3DSA:1.10.357.10 14 198 3.4E-15 T 14-10-2018 A4R43_11835 b9578ee56d30b28cbda6246503329d41 201 SUPERFAMILY SSF48498 91 189 2.07E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4R43_11835 b9578ee56d30b28cbda6246503329d41 201 SUPERFAMILY SSF46689 17 85 1.74E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_19225 c32cd1e208201c42b44007416726f474 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 329 1.1E-52 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_27290 0e10c93d13f62c1848ebc54468d91f67 183 Gene3D G3DSA:3.40.50.360 1 182 5.2E-36 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_27290 0e10c93d13f62c1848ebc54468d91f67 183 Pfam PF03358 NADPH-dependent FMN reductase 1 138 2.3E-22 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4R43_27290 0e10c93d13f62c1848ebc54468d91f67 183 SUPERFAMILY SSF52218 1 173 1.84E-29 T 14-10-2018 IPR029039 Flavoprotein-like superfamily A4R43_01260 a9c6f901feb838bc825896fe63cab24f 161 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 4 132 7.0E-8 T 14-10-2018 IPR024412 Lsr2 A4R43_01260 a9c6f901feb838bc825896fe63cab24f 161 Gene3D G3DSA:3.30.60.230 1 58 4.9E-15 T 14-10-2018 A4R43_01260 a9c6f901feb838bc825896fe63cab24f 161 Pfam PF11774 Lsr2 4 144 3.1E-18 T 14-10-2018 IPR024412 Lsr2 A4R43_34225 a7612e7492e6b4f4aa54a87859a4b35b 465 Pfam PF01425 Amidase 24 448 4.6E-92 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_34225 a7612e7492e6b4f4aa54a87859a4b35b 465 SUPERFAMILY SSF75304 2 456 1.96E-129 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_34225 a7612e7492e6b4f4aa54a87859a4b35b 465 Gene3D G3DSA:3.90.1300.10 1 464 3.3E-133 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_38280 d682b7d975b0486b2a9a78d3f10c617a 442 Gene3D G3DSA:1.10.10.2840 267 396 4.4E-22 T 14-10-2018 A4R43_38280 d682b7d975b0486b2a9a78d3f10c617a 442 Pfam PF13556 PucR C-terminal helix-turn-helix domain 335 392 2.3E-18 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_12690 20adea332058666347f349e3b65ab91b 276 Pfam PF02517 CAAX protease self-immunity 125 217 3.8E-12 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A4R43_41170 7726ca3183b70eafbf4423089f99a0b3 153 Gene3D G3DSA:1.25.40.10 66 152 1.3E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_41170 7726ca3183b70eafbf4423089f99a0b3 153 SUPERFAMILY SSF48452 107 147 4.55E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_02225 2d087c1852e3a8c8bceac08c51b34428 255 Pfam PF12867 DinB superfamily 93 240 6.0E-11 T 14-10-2018 IPR024775 DinB-like domain A4R43_02225 2d087c1852e3a8c8bceac08c51b34428 255 SUPERFAMILY SSF109854 92 211 4.94E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A4R43_10175 86c20b76839a3a29e69e0281f22d4c7c 390 SUPERFAMILY SSF53448 126 234 4.41E-6 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_00870 a0427005ea3c718d43cd762aa1af3bf1 479 Gene3D G3DSA:1.20.1740.10 12 460 1.8E-34 T 14-10-2018 A4R43_00870 a0427005ea3c718d43cd762aa1af3bf1 479 Pfam PF13520 Amino acid permease 19 429 4.0E-24 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_00870 a0427005ea3c718d43cd762aa1af3bf1 479 PIRSF PIRSF006060 1 473 4.6E-48 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4R43_01390 d89d3d054b3743ab503057515176095d 311 PRINTS PR00990 Ribokinase signature 43 62 4.6E-9 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_01390 d89d3d054b3743ab503057515176095d 311 PRINTS PR00990 Ribokinase signature 16 37 4.6E-9 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_01390 d89d3d054b3743ab503057515176095d 311 PRINTS PR00990 Ribokinase signature 177 192 4.6E-9 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_01390 d89d3d054b3743ab503057515176095d 311 PRINTS PR00990 Ribokinase signature 221 232 4.6E-9 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A4R43_01390 d89d3d054b3743ab503057515176095d 311 Pfam PF00294 pfkB family carbohydrate kinase 13 294 1.7E-42 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB A4R43_01390 d89d3d054b3743ab503057515176095d 311 Gene3D G3DSA:3.40.1190.20 10 302 2.3E-59 T 14-10-2018 IPR029056 Ribokinase-like A4R43_01390 d89d3d054b3743ab503057515176095d 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 48 72 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_01390 d89d3d054b3743ab503057515176095d 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4R43_01390 d89d3d054b3743ab503057515176095d 311 SUPERFAMILY SSF53613 12 296 2.65E-53 T 14-10-2018 IPR029056 Ribokinase-like A4R43_37315 fdca605632f33e5ef518dde4c01d954b 357 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 179 1.1E-24 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4R43_37315 fdca605632f33e5ef518dde4c01d954b 357 Gene3D G3DSA:3.40.50.720 2 335 5.1E-69 T 14-10-2018 A4R43_37315 fdca605632f33e5ef518dde4c01d954b 357 SUPERFAMILY SSF51735 3 328 5.9E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_14555 b7cc1639a1459027e6b80cd9100003e6 303 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 53 115 1.1E-13 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4R43_14555 b7cc1639a1459027e6b80cd9100003e6 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 270 5.5E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_14555 b7cc1639a1459027e6b80cd9100003e6 303 SUPERFAMILY SSF161098 53 257 5.36E-42 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_14555 b7cc1639a1459027e6b80cd9100003e6 303 Gene3D G3DSA:1.10.3720.10 39 274 1.3E-52 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_01525 0d85a752fa7bc7fc73f61a914ead700d 213 Gene3D G3DSA:2.160.10.10 7 190 9.1E-34 T 14-10-2018 A4R43_01525 0d85a752fa7bc7fc73f61a914ead700d 213 SUPERFAMILY SSF51161 11 140 5.54E-24 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_06820 a4440b72d1d067749590f0af172bc0b5 160 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 18 154 3.5E-15 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 A4R43_01400 80316103228f6bca4ae347ae07222e8c 361 Gene3D G3DSA:3.40.50.1820 44 359 1.7E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_01400 80316103228f6bca4ae347ae07222e8c 361 Pfam PF00756 Putative esterase 83 321 2.8E-28 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A4R43_01400 80316103228f6bca4ae347ae07222e8c 361 SUPERFAMILY SSF53474 73 330 4.23E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_25950 26933b13d361d2ab10891ac50a6d74ec 747 Pfam PF13625 Helicase conserved C-terminal domain 463 585 2.6E-40 T 14-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A4R43_27240 b5f74129fa01684fdfad53239ee981eb 375 SUPERFAMILY SSF52540 15 291 4.01E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_27240 b5f74129fa01684fdfad53239ee981eb 375 Pfam PF02374 Anion-transporting ATPase 16 294 6.2E-26 T 14-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A4R43_00910 cb204f310413885a3fc3c1b4911d98da 159 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 15 146 9.7E-9 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 A4R43_05945 45ce513076fe9d1d06829f9e45f02bf9 317 Pfam PF13556 PucR C-terminal helix-turn-helix domain 263 308 2.1E-10 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A4R43_05945 45ce513076fe9d1d06829f9e45f02bf9 317 Gene3D G3DSA:1.10.10.2840 186 314 1.3E-13 T 14-10-2018 A4R43_18095 778cc82e10f3d21303d42fb6ea623581 158 Pfam PF11343 Protein of unknown function (DUF3145) 1 156 5.5E-73 T 14-10-2018 IPR021491 Protein of unknown function DUF3145 A4R43_16140 3b155bb090b5e87f350b9ab24f96038d 329 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 6 328 3.4E-90 T 14-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related A4R43_16140 3b155bb090b5e87f350b9ab24f96038d 329 Gene3D G3DSA:3.20.20.30 3 328 9.6E-75 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_16140 3b155bb090b5e87f350b9ab24f96038d 329 SUPERFAMILY SSF51679 5 327 3.93E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_16140 3b155bb090b5e87f350b9ab24f96038d 329 Pfam PF00296 Luciferase-like monooxygenase 8 301 2.9E-56 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_04130 5145d54091e2c8cde0083ca28b5a8587 487 Pfam PF01425 Amidase 53 467 2.4E-85 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_04130 5145d54091e2c8cde0083ca28b5a8587 487 SUPERFAMILY SSF75304 3 484 9.42E-123 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_04130 5145d54091e2c8cde0083ca28b5a8587 487 ProSitePatterns PS00571 Amidases signature. 141 172 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4R43_04130 5145d54091e2c8cde0083ca28b5a8587 487 Gene3D G3DSA:3.90.1300.10 3 487 8.9E-157 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4R43_28585 61142fb185b469273aacc4c552b24731 183 Pfam PF00210 Ferritin-like domain 14 149 9.9E-33 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A4R43_28585 61142fb185b469273aacc4c552b24731 183 SUPERFAMILY SSF47240 10 155 3.86E-42 T 14-10-2018 IPR009078 Ferritin-like superfamily A4R43_28585 61142fb185b469273aacc4c552b24731 183 Gene3D G3DSA:1.20.1260.10 4 182 4.6E-49 T 14-10-2018 IPR012347 Ferritin-like A4R43_35395 7506ab51bec5bfda77a3a87671a96b69 146 Pfam PF07681 DoxX 10 91 7.7E-18 T 14-10-2018 IPR032808 DoxX family A4R43_05895 637001a46ab7c3ac93c64d448cc4fffb 507 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 433 5.7E-58 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_05895 637001a46ab7c3ac93c64d448cc4fffb 507 Pfam PF00474 Sodium:solute symporter family 34 433 1.2E-81 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4R43_05895 637001a46ab7c3ac93c64d448cc4fffb 507 Gene3D G3DSA:1.20.1730.10 20 483 8.5E-58 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily A4R43_12050 5ccbf085ff7167b567474c57828c5686 427 Pfam PF03600 Citrate transporter 13 371 5.8E-44 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A4R43_12050 5ccbf085ff7167b567474c57828c5686 427 TIGRFAM TIGR00784 citMHS: citrate transporter 1 426 1.3E-150 T 14-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 A4R43_40545 e223d60270f454136cd3b7b0f2627696 141 Gene3D G3DSA:2.30.110.10 1 140 5.2E-57 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_40545 e223d60270f454136cd3b7b0f2627696 141 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 28 138 1.0E-38 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_40545 e223d60270f454136cd3b7b0f2627696 141 Pfam PF04075 F420H(2)-dependent quinone reductase 11 138 1.4E-47 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_40545 e223d60270f454136cd3b7b0f2627696 141 SUPERFAMILY SSF50475 30 133 1.96E-6 T 14-10-2018 A4R43_06355 ea953a3dd57cfd49a303f290d6357135 543 Gene3D G3DSA:3.40.190.10 89 221 2.2E-14 T 14-10-2018 A4R43_06355 ea953a3dd57cfd49a303f290d6357135 543 SUPERFAMILY SSF53850 25 541 1.45E-49 T 14-10-2018 A4R43_06355 ea953a3dd57cfd49a303f290d6357135 543 Pfam PF13416 Bacterial extracellular solute-binding protein 124 416 4.9E-9 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4R43_14475 27657106437a29487580eb69ba724962 290 SUPERFAMILY SSF53474 37 285 1.33E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14475 27657106437a29487580eb69ba724962 290 Pfam PF12697 Alpha/beta hydrolase family 56 279 4.6E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_14475 27657106437a29487580eb69ba724962 290 Gene3D G3DSA:3.40.50.1820 6 288 5.1E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_23675 3d3677390966b1b28599cbf414d8aeb3 299 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 9 289 55.877 T 14-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 A4R43_23675 3d3677390966b1b28599cbf414d8aeb3 299 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 155 3.2E-28 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4R43_23675 3d3677390966b1b28599cbf414d8aeb3 299 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 6 288 1.1E-156 T 14-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 A4R43_23675 3d3677390966b1b28599cbf414d8aeb3 299 Gene3D G3DSA:3.40.50.10320 5 295 1.4E-84 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_23675 3d3677390966b1b28599cbf414d8aeb3 299 SUPERFAMILY SSF102588 4 288 1.31E-80 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4R43_12025 30427c71fc67aad65e90c7aab6e7b646 476 Pfam PF09362 Domain of unknown function (DUF1996) 313 453 6.3E-15 T 14-10-2018 IPR018535 Domain of unknown function DUF1996 A4R43_40635 ca40e5add5293aeaf24e209c087f0479 150 Gene3D G3DSA:1.10.10.10 1 150 2.0E-49 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_40635 ca40e5add5293aeaf24e209c087f0479 150 SUPERFAMILY SSF46785 6 144 1.55E-40 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40635 ca40e5add5293aeaf24e209c087f0479 150 Pfam PF01638 HxlR-like helix-turn-helix 19 105 3.9E-24 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_25690 f03f2f03335eacd10655f6b7c0bf2ad7 372 Pfam PF09594 Glycosyltransferase family 87 55 286 5.7E-54 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_40405 8b2963166130c9d38a7a4de34f45f9e1 221 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 213 3.4E-26 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A4R43_40405 8b2963166130c9d38a7a4de34f45f9e1 221 Gene3D G3DSA:3.90.226.10 5 221 1.6E-53 T 14-10-2018 A4R43_40405 8b2963166130c9d38a7a4de34f45f9e1 221 SUPERFAMILY SSF52096 9 217 4.83E-43 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4R43_04030 6228737eb918ab1f939ca0250bae9fb2 389 SUPERFAMILY SSF50939 20 383 1.51E-46 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_04030 6228737eb918ab1f939ca0250bae9fb2 389 Gene3D G3DSA:2.120.10.10 16 291 2.7E-35 T 14-10-2018 A4R43_04030 6228737eb918ab1f939ca0250bae9fb2 389 Pfam PF13088 BNR repeat-like domain 33 364 1.4E-63 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 A4R43_13470 18db386b6b1a34785c3b8bfa34eb7ef6 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 312 6.9E-36 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_13470 18db386b6b1a34785c3b8bfa34eb7ef6 314 Gene3D G3DSA:1.10.3720.10 85 305 5.0E-22 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_13470 18db386b6b1a34785c3b8bfa34eb7ef6 314 SUPERFAMILY SSF161098 91 298 1.96E-19 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_20790 028f7dbe1d155433949bd68acb4cc11d 618 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 72 231 8.8E-26 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4R43_20430 d40ee49e790c736552263ba3a531354b 180 Gene3D G3DSA:2.60.120.10 23 168 8.6E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold A4R43_20430 d40ee49e790c736552263ba3a531354b 180 Pfam PF05995 Cysteine dioxygenase type I 53 163 7.9E-18 T 14-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 A4R43_20430 d40ee49e790c736552263ba3a531354b 180 SUPERFAMILY SSF51182 24 163 2.97E-28 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily A4R43_12315 ef46c4d564ada51570287d5805ef7d6d 78 Gene3D G3DSA:1.10.260.40 1 33 1.0E-6 T 14-10-2018 A4R43_35750 d3c73735297312509176f537db0c5882 279 SUPERFAMILY SSF110849 92 147 7.98E-9 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A4R43_34540 d314ec6204ef7a7a8e2302535fe12ca7 797 SUPERFAMILY SSF160424 12 143 2.35E-18 T 14-10-2018 IPR036170 Probable antitoxin YezG superfamily A4R43_34540 d314ec6204ef7a7a8e2302535fe12ca7 797 Pfam PF14021 Tuberculosis necrotizing toxin 703 787 5.4E-28 T 14-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 A4R43_21595 6cb770b947477a7a17d071a369cc43e2 247 SUPERFAMILY SSF51735 4 203 4.2E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_21595 6cb770b947477a7a17d071a369cc43e2 247 Gene3D G3DSA:3.40.50.720 4 246 7.2E-43 T 14-10-2018 A4R43_21595 6cb770b947477a7a17d071a369cc43e2 247 Pfam PF13460 NAD(P)H-binding 9 133 3.7E-20 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_27865 c62440ed42ba777069c2c30d39a4ccc5 214 SUPERFAMILY SSF53474 7 213 8.5E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_27865 c62440ed42ba777069c2c30d39a4ccc5 214 Pfam PF01738 Dienelactone hydrolase family 22 212 4.6E-22 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 A4R43_27865 c62440ed42ba777069c2c30d39a4ccc5 214 Gene3D G3DSA:3.40.50.1820 5 211 5.0E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_34875 dbd5ef0567485dd71bb6ad1ddb0a675a 427 Gene3D G3DSA:1.10.260.40 3 71 2.4E-12 T 14-10-2018 A4R43_34875 dbd5ef0567485dd71bb6ad1ddb0a675a 427 Pfam PF13560 Helix-turn-helix domain 8 57 1.9E-13 T 14-10-2018 A4R43_34875 dbd5ef0567485dd71bb6ad1ddb0a675a 427 SUPERFAMILY SSF47413 6 55 1.98E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4R43_34875 dbd5ef0567485dd71bb6ad1ddb0a675a 427 SMART SM00530 11 68 7.9E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4R43_34875 dbd5ef0567485dd71bb6ad1ddb0a675a 427 SUPERFAMILY SSF48452 188 374 1.14E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_29870 db7922c7f3e5e083389a6ede8c521c16 101 Gene3D G3DSA:1.10.10.10 1 61 3.3E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_29870 db7922c7f3e5e083389a6ede8c521c16 101 SUPERFAMILY SSF46785 9 59 5.27E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_36355 05b070733be92cc6947f2206c46df5eb 218 Gene3D G3DSA:1.20.1540.10 28 209 3.3E-13 T 14-10-2018 IPR035952 Rhomboid-like superfamily A4R43_36355 05b070733be92cc6947f2206c46df5eb 218 Pfam PF01694 Rhomboid family 72 203 3.4E-22 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4R43_36355 05b070733be92cc6947f2206c46df5eb 218 SUPERFAMILY SSF144091 33 205 9.42E-26 T 14-10-2018 A4R43_32590 9992bd3f2fec249c819d212e5b982af8 202 Pfam PF06197 Protein of unknown function (DUF998) 6 192 1.3E-17 T 14-10-2018 IPR009339 Protein of unknown function DUF998 A4R43_17285 6cce96a68ac0de7081bb70cc811ac13d 169 Gene3D G3DSA:3.30.1310.10 15 115 1.3E-7 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_17285 6cce96a68ac0de7081bb70cc811ac13d 169 SUPERFAMILY SSF82607 28 110 1.27E-6 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_17285 6cce96a68ac0de7081bb70cc811ac13d 169 Pfam PF02575 YbaB/EbfC DNA-binding family 26 107 8.5E-10 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_11680 a6888e49a7c69db8a98765bc53cd1f8b 161 Pfam PF09350 Domain of unknown function (DUF1992) 14 84 3.1E-22 T 14-10-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain A4R43_20755 fcef3fc1beb92b83ca67e3e14ef021d5 259 Gene3D G3DSA:3.40.50.150 4 130 1.7E-11 T 14-10-2018 A4R43_20755 fcef3fc1beb92b83ca67e3e14ef021d5 259 Pfam PF13649 Methyltransferase domain 40 122 2.2E-6 T 14-10-2018 A4R43_20755 fcef3fc1beb92b83ca67e3e14ef021d5 259 SUPERFAMILY SSF53335 18 123 1.47E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_20485 417ab23e48ae0179a4cb3a6eac5f4f7e 166 SMART SM00347 46 147 5.3E-21 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20485 417ab23e48ae0179a4cb3a6eac5f4f7e 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 3.8E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20485 417ab23e48ae0179a4cb3a6eac5f4f7e 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 3.8E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20485 417ab23e48ae0179a4cb3a6eac5f4f7e 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 3.8E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_20485 417ab23e48ae0179a4cb3a6eac5f4f7e 166 SUPERFAMILY SSF46785 28 160 1.39E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_20485 417ab23e48ae0179a4cb3a6eac5f4f7e 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4R43_20485 417ab23e48ae0179a4cb3a6eac5f4f7e 166 Gene3D G3DSA:1.10.10.10 22 166 1.5E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_20485 417ab23e48ae0179a4cb3a6eac5f4f7e 166 Pfam PF12802 MarR family 51 111 4.5E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40035 af9d06cc797a0b0081c286c0498999c2 437 Pfam PF00135 Carboxylesterase family 4 304 2.5E-63 T 14-10-2018 IPR002018 Carboxylesterase, type B A4R43_40035 af9d06cc797a0b0081c286c0498999c2 437 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 170 185 - T 14-10-2018 IPR019826 Carboxylesterase type B, active site A4R43_40035 af9d06cc797a0b0081c286c0498999c2 437 Gene3D G3DSA:3.40.50.1820 1 434 3.4E-89 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_40035 af9d06cc797a0b0081c286c0498999c2 437 SUPERFAMILY SSF53474 3 420 1.52E-76 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_20655 a950bd0abf6a4beed532c4aee486d8df 125 Gene3D G3DSA:2.40.350.10 1 125 2.8E-36 T 14-10-2018 IPR023159 SO1590-like superfamily A4R43_20655 a950bd0abf6a4beed532c4aee486d8df 125 SUPERFAMILY SSF159238 3 124 1.83E-30 T 14-10-2018 IPR023159 SO1590-like superfamily A4R43_20655 a950bd0abf6a4beed532c4aee486d8df 125 Pfam PF11528 Protein of unknown function (DUF3224) 5 122 7.8E-32 T 14-10-2018 IPR021607 Protein of unknown function DUF3224 A4R43_13860 374065ef640a072cb14f8c9b18f8f686 202 Pfam PF13785 Domain of unknown function (DUF4178) 59 191 3.2E-33 T 14-10-2018 IPR025235 Domain of unknown function DUF4178 A4R43_11170 73a7d8671b93438d7417494cb9644ccb 452 SUPERFAMILY SSF140459 18 166 1.8E-6 T 14-10-2018 A4R43_11170 73a7d8671b93438d7417494cb9644ccb 452 Gene3D G3DSA:1.10.287.1060 12 98 1.7E-6 T 14-10-2018 A4R43_11170 73a7d8671b93438d7417494cb9644ccb 452 Pfam PF06013 Proteins of 100 residues with WXG 14 90 1.5E-7 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_38545 21c890e378d2b6f66fcf9dd857d079ab 472 SUPERFAMILY SSF53474 71 442 1.29E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_38545 21c890e378d2b6f66fcf9dd857d079ab 472 Pfam PF08386 TAP-like protein 375 466 1.0E-26 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4R43_37775 69f74bc96b0c1a6491664f36f83e9772 300 Gene3D G3DSA:2.70.70.10 31 189 2.7E-32 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_37775 69f74bc96b0c1a6491664f36f83e9772 300 SUPERFAMILY SSF51261 61 158 2.14E-29 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_37775 69f74bc96b0c1a6491664f36f83e9772 300 Pfam PF01551 Peptidase family M23 65 158 7.9E-25 T 14-10-2018 IPR016047 Peptidase M23 A4R43_40225 48f00c56c6aac3af98e8cfd655f234f7 164 Gene3D G3DSA:2.40.33.20 6 159 5.1E-9 T 14-10-2018 A4R43_40225 48f00c56c6aac3af98e8cfd655f234f7 164 SUPERFAMILY SSF50800 31 159 2.46E-19 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A4R43_07485 9ae9308ef891145a25d07a8f70b9c408 275 Pfam PF00535 Glycosyl transferase family 2 4 125 3.3E-21 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_07485 9ae9308ef891145a25d07a8f70b9c408 275 Gene3D G3DSA:3.90.550.10 1 214 4.3E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_07485 9ae9308ef891145a25d07a8f70b9c408 275 SUPERFAMILY SSF53448 2 225 1.31E-42 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_10550 09f703905289f29b171531b057cc3f83 653 Pfam PF01757 Acyltransferase family 8 305 4.3E-22 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A4R43_17580 589e888659ed9c7dd3174f92a4b86bf1 202 Pfam PF10821 Protein of unknown function (DUF2567) 52 198 3.6E-10 T 14-10-2018 IPR021213 Protein of unknown function DUF2567 A4R43_20695 12bfd0db407a111e8c978f1b4acd10e4 279 SUPERFAMILY SSF55874 135 230 2.87E-5 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_20695 12bfd0db407a111e8c978f1b4acd10e4 279 Gene3D G3DSA:3.30.750.24 2 93 1.3E-5 T 14-10-2018 IPR036513 STAS domain superfamily A4R43_31615 5e41f95cc419adf921084c048845c6b7 188 Gene3D G3DSA:1.10.3210.10 11 173 1.0E-40 T 14-10-2018 A4R43_31615 5e41f95cc419adf921084c048845c6b7 188 Pfam PF13328 HD domain 32 170 6.9E-20 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_31615 5e41f95cc419adf921084c048845c6b7 188 SUPERFAMILY SSF109604 20 169 2.95E-39 T 14-10-2018 A4R43_31615 5e41f95cc419adf921084c048845c6b7 188 SMART SM00471 47 148 2.7E-6 T 14-10-2018 IPR003607 HD/PDEase domain A4R43_12275 ca3702002c4884958939713cce5c5a02 91 SUPERFAMILY SSF140453 2 87 4.05E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_35435 609711e19867a086fa6a2716e33b5dd3 297 SUPERFAMILY SSF53448 1 219 5.16E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_35435 609711e19867a086fa6a2716e33b5dd3 297 Pfam PF00535 Glycosyl transferase family 2 2 155 8.1E-20 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_35435 609711e19867a086fa6a2716e33b5dd3 297 Gene3D G3DSA:3.90.550.10 1 202 4.6E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_28220 645b9430e43c20d7db3f7613b901396f 350 Pfam PF04443 Acyl-protein synthetase, LuxE 20 346 1.8E-46 T 14-10-2018 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 A4R43_28220 645b9430e43c20d7db3f7613b901396f 350 Gene3D G3DSA:3.40.50.12780 2 312 1.4E-15 T 14-10-2018 A4R43_28220 645b9430e43c20d7db3f7613b901396f 350 SUPERFAMILY SSF56801 153 315 2.88E-7 T 14-10-2018 A4R43_00150 dd392d71714f001d0b02e771511d3806 208 Gene3D G3DSA:3.40.430.10 2 190 2.2E-42 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_00150 dd392d71714f001d0b02e771511d3806 208 SUPERFAMILY SSF53597 2 192 2.75E-30 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_00150 dd392d71714f001d0b02e771511d3806 208 Pfam PF01872 RibD C-terminal domain 2 187 6.0E-30 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_12920 bca7efb4538b816bd4593d216cb6b9d5 313 Gene3D G3DSA:3.40.50.1980 138 311 6.1E-44 T 14-10-2018 A4R43_12920 bca7efb4538b816bd4593d216cb6b9d5 313 Pfam PF01497 Periplasmic binding protein 48 277 2.9E-23 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain A4R43_12920 bca7efb4538b816bd4593d216cb6b9d5 313 Gene3D G3DSA:3.40.50.1980 25 136 1.5E-22 T 14-10-2018 A4R43_12920 bca7efb4538b816bd4593d216cb6b9d5 313 SUPERFAMILY SSF53807 30 305 9.03E-52 T 14-10-2018 A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 Pfam PF00106 short chain dehydrogenase 12 197 1.5E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.3E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.3E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.3E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.3E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.3E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 Gene3D G3DSA:3.40.50.720 8 270 2.2E-56 T 14-10-2018 A4R43_24350 7d5a797063f76c72a9eb4b80f543dbfa 279 SUPERFAMILY SSF51735 10 253 7.3E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_38750 a1b45050b6abf6feaa2d56bc170332a9 382 SUPERFAMILY SSF56601 12 379 9.06E-77 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_38750 a1b45050b6abf6feaa2d56bc170332a9 382 Gene3D G3DSA:3.40.710.30 8 382 2.3E-114 T 14-10-2018 A4R43_38750 a1b45050b6abf6feaa2d56bc170332a9 382 Pfam PF00144 Beta-lactamase 19 362 2.3E-66 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_15760 987e64dfa8f1fd55c41d50006ee779a5 482 Pfam PF02653 Branched-chain amino acid transport system / permease component 79 466 5.4E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_24325 075a586e30d6f78c39d62be1c301140c 106 SUPERFAMILY SSF54292 3 99 6.97E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4R43_24325 075a586e30d6f78c39d62be1c301140c 106 PRINTS PR00355 Adrenodoxin signature 59 73 9.5E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4R43_24325 075a586e30d6f78c39d62be1c301140c 106 PRINTS PR00355 Adrenodoxin signature 40 50 9.5E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4R43_24325 075a586e30d6f78c39d62be1c301140c 106 PRINTS PR00355 Adrenodoxin signature 83 91 9.5E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4R43_24325 075a586e30d6f78c39d62be1c301140c 106 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 40 50 - T 14-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4R43_24325 075a586e30d6f78c39d62be1c301140c 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 90 4.0E-11 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4R43_24325 075a586e30d6f78c39d62be1c301140c 106 Gene3D G3DSA:3.10.20.30 2 106 1.5E-29 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_39360 5448dd863cd5357dc346fe0186946b04 196 SUPERFAMILY SSF55166 67 167 1.73E-13 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_39360 5448dd863cd5357dc346fe0186946b04 196 Gene3D G3DSA:3.30.1380.10 47 186 2.1E-7 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4R43_39360 5448dd863cd5357dc346fe0186946b04 196 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 76 158 1.8E-5 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A4R43_16415 38db58b7cd94041672c927f774520204 549 Pfam PF05960 Bacterial protein of unknown function (DUF885) 23 543 5.0E-149 T 14-10-2018 IPR010281 Protein of unknown function DUF885 A4R43_06815 bbacf77ce940195b07a6b32f34eca945 497 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 438 6.9E-140 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A4R43_24110 611ddb121f5e401253c5f18196bb78d6 204 SUPERFAMILY SSF51445 7 191 1.05E-21 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily A4R43_24110 611ddb121f5e401253c5f18196bb78d6 204 Pfam PF01183 Glycosyl hydrolases family 25 10 183 5.4E-16 T 14-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 A4R43_24110 611ddb121f5e401253c5f18196bb78d6 204 Gene3D G3DSA:3.20.20.80 7 190 7.2E-21 T 14-10-2018 A4R43_36925 3a365157b7ffd068e3ad3c4ae6efa139 322 SUPERFAMILY SSF52317 7 197 7.16E-39 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_36925 3a365157b7ffd068e3ad3c4ae6efa139 322 SUPERFAMILY SSF46689 268 317 1.54E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_36925 3a365157b7ffd068e3ad3c4ae6efa139 322 Gene3D G3DSA:1.10.10.60 215 319 1.2E-23 T 14-10-2018 A4R43_36925 3a365157b7ffd068e3ad3c4ae6efa139 322 SMART SM00342 231 314 9.8E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_36925 3a365157b7ffd068e3ad3c4ae6efa139 322 Gene3D G3DSA:3.40.50.880 4 209 4.2E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_36925 3a365157b7ffd068e3ad3c4ae6efa139 322 SUPERFAMILY SSF46689 217 264 3.34E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_36925 3a365157b7ffd068e3ad3c4ae6efa139 322 Pfam PF12833 Helix-turn-helix domain 237 316 3.7E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4R43_36925 3a365157b7ffd068e3ad3c4ae6efa139 322 Pfam PF01965 DJ-1/PfpI family 84 176 3.4E-10 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4R43_08535 5cfd065c2191083bb8e41d20e8fe1b82 123 SUPERFAMILY SSF46785 7 105 4.8E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_08535 5cfd065c2191083bb8e41d20e8fe1b82 123 Pfam PF01638 HxlR-like helix-turn-helix 21 104 2.2E-26 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_08535 5cfd065c2191083bb8e41d20e8fe1b82 123 Gene3D G3DSA:1.10.10.10 2 120 4.8E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_41775 ab0e9ab68c84fb935425d92abe09e470 421 Gene3D G3DSA:3.30.450.40 37 220 1.1E-54 T 14-10-2018 IPR029016 GAF-like domain superfamily A4R43_41775 ab0e9ab68c84fb935425d92abe09e470 421 Pfam PF01590 GAF domain 109 217 7.1E-8 T 14-10-2018 IPR003018 GAF domain GO:0005515 A4R43_06010 fe1580f87c184b8ddd6f403a01232f67 481 Pfam PF00860 Permease family 40 434 1.3E-27 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A4R43_31470 881e745522629d6bea1e31b9d0899845 337 SUPERFAMILY SSF48208 34 289 9.35E-21 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4R43_31470 881e745522629d6bea1e31b9d0899845 337 Pfam PF03663 Glycosyl hydrolase family 76 46 306 7.4E-22 T 14-10-2018 IPR005198 Glycoside hydrolase, family 76 A4R43_31470 881e745522629d6bea1e31b9d0899845 337 Gene3D G3DSA:1.50.10.20 4 337 8.2E-82 T 14-10-2018 A4R43_02935 e4bcbeaf42429783078dfd0aec11d8c6 302 SUPERFAMILY SSF53474 3 302 8.54E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_02935 e4bcbeaf42429783078dfd0aec11d8c6 302 Pfam PF12697 Alpha/beta hydrolase family 51 285 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_02935 e4bcbeaf42429783078dfd0aec11d8c6 302 Gene3D G3DSA:1.10.10.800 138 226 3.3E-75 T 14-10-2018 A4R43_02935 e4bcbeaf42429783078dfd0aec11d8c6 302 Gene3D G3DSA:3.40.50.1820 12 284 3.3E-75 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_16815 1ceda6f5008e9dd95b3f0ea66e72c851 84 Gene3D G3DSA:3.10.350.10 27 79 1.1E-6 T 14-10-2018 IPR036779 LysM domain superfamily A4R43_16815 1ceda6f5008e9dd95b3f0ea66e72c851 84 Pfam PF01476 LysM domain 32 78 8.6E-5 T 14-10-2018 IPR018392 LysM domain A4R43_19615 a9dc308899111c5adad1b123e63e8624 143 Gene3D G3DSA:3.30.530.20 2 143 2.2E-16 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_19615 a9dc308899111c5adad1b123e63e8624 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 142 1.2E-18 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_19615 a9dc308899111c5adad1b123e63e8624 143 SUPERFAMILY SSF55961 1 142 6.09E-24 T 14-10-2018 A4R43_39730 2921988f8e0599428e93754b381e8522 226 SUPERFAMILY SSF51735 1 216 4.29E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_39730 2921988f8e0599428e93754b381e8522 226 Gene3D G3DSA:3.40.50.720 1 217 1.7E-23 T 14-10-2018 A4R43_39730 2921988f8e0599428e93754b381e8522 226 Pfam PF13460 NAD(P)H-binding 8 205 1.0E-16 T 14-10-2018 IPR016040 NAD(P)-binding domain A4R43_29220 e80f59a4e173208b776ff74313a77395 152 Gene3D G3DSA:1.10.10.60 42 89 3.0E-6 T 14-10-2018 A4R43_11900 7731acafb7e2c67c32f61977c72e610a 283 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 267 5.2E-27 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_41825 44c561d293c2334e11a82b0f0224e8a7 415 SUPERFAMILY SSF53448 13 232 2.34E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_41825 44c561d293c2334e11a82b0f0224e8a7 415 Pfam PF04138 GtrA-like protein 288 405 1.1E-11 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4R43_41825 44c561d293c2334e11a82b0f0224e8a7 415 Gene3D G3DSA:3.90.550.10 6 251 2.1E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_41825 44c561d293c2334e11a82b0f0224e8a7 415 Pfam PF00535 Glycosyl transferase family 2 24 191 6.7E-20 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4R43_30140 9bea82d0332f598793d17214dbc90378 409 Pfam PF02470 MlaD protein 26 102 1.1E-5 T 14-10-2018 IPR003399 Mce/MlaD A4R43_04910 bc381ff5d27fc46109984da51bf13090 391 Pfam PF06224 Winged helix DNA-binding domain 30 369 1.3E-57 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 A4R43_10055 6d565903965b5a53f10e0b59451eef7f 116 Pfam PF13564 DoxX-like family 10 108 3.4E-16 T 14-10-2018 IPR032808 DoxX family A4R43_18945 44ad4184d43fd4950c4e4dc8f8a106a7 258 Pfam PF01553 Acyltransferase 59 185 5.3E-24 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_18945 44ad4184d43fd4950c4e4dc8f8a106a7 258 SUPERFAMILY SSF69593 34 248 1.31E-40 T 14-10-2018 A4R43_18945 44ad4184d43fd4950c4e4dc8f8a106a7 258 SMART SM00563 71 189 3.1E-30 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4R43_07885 9e97b858bdf6702a3d2bad6bb53b484a 397 SUPERFAMILY SSF52540 6 252 1.44E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_07885 9e97b858bdf6702a3d2bad6bb53b484a 397 Pfam PF13191 AAA ATPase domain 3 167 6.8E-17 T 14-10-2018 A4R43_05410 a5f763cde1f9bcc0c09dd80fe68105ca 88 Pfam PF14019 Protein of unknown function (DUF4235) 6 82 6.7E-26 T 14-10-2018 IPR025329 Protein of unknown function DUF4235 A4R43_20350 8e430340008ba451dcb0b45f7e4b8aca 239 Gene3D G3DSA:3.30.530.20 2 151 3.4E-13 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_20350 8e430340008ba451dcb0b45f7e4b8aca 239 SUPERFAMILY SSF55961 5 125 3.47E-13 T 14-10-2018 A4R43_06515 a47c4f6072739d70790535f719ceb399 244 Pfam PF13649 Methyltransferase domain 40 132 3.0E-12 T 14-10-2018 A4R43_06515 a47c4f6072739d70790535f719ceb399 244 Gene3D G3DSA:2.20.25.570 140 202 5.3E-38 T 14-10-2018 A4R43_06515 a47c4f6072739d70790535f719ceb399 244 SUPERFAMILY SSF53335 11 236 1.25E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_06515 a47c4f6072739d70790535f719ceb399 244 Gene3D G3DSA:3.40.50.150 37 234 5.3E-38 T 14-10-2018 A4R43_11520 85fead8d13f36942987b893660daeea5 227 Gene3D G3DSA:1.10.10.1320 4 61 5.3E-14 T 14-10-2018 A4R43_11520 85fead8d13f36942987b893660daeea5 227 Pfam PF13490 Putative zinc-finger 8 37 2.3E-9 T 14-10-2018 IPR027383 Putative zinc-finger A4R43_13240 0874b02137030f8948ee632412fde54a 388 SUPERFAMILY SSF56300 163 383 3.01E-32 T 14-10-2018 A4R43_13240 0874b02137030f8948ee632412fde54a 388 Pfam PF00149 Calcineurin-like phosphoesterase 162 328 6.4E-8 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_13240 0874b02137030f8948ee632412fde54a 388 Gene3D G3DSA:3.60.21.10 162 348 9.6E-16 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like A4R43_15080 faecd96db5b667cff78c654254174c28 155 Pfam PF14022 Protein of unknown function (DUF4238) 11 111 7.0E-8 T 14-10-2018 IPR025332 Protein of unknown function DUF4238 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00385 P450 superfamily signature 310 321 1.3E-13 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00385 P450 superfamily signature 391 402 1.3E-13 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00385 P450 superfamily signature 270 287 1.3E-13 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00385 P450 superfamily signature 382 391 1.3E-13 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 384 393 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 Gene3D G3DSA:1.10.630.10 27 445 3.6E-95 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 Pfam PF00067 Cytochrome P450 21 437 1.0E-61 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 SUPERFAMILY SSF48264 20 444 1.31E-93 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00463 E-class P450 group I signature 259 276 6.1E-19 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00463 E-class P450 group I signature 349 373 6.1E-19 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00463 E-class P450 group I signature 47 66 6.1E-19 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00463 E-class P450 group I signature 309 327 6.1E-19 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00463 E-class P450 group I signature 381 391 6.1E-19 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_10975 e9ba368398d2fc2c780a43c9046fedac 445 PRINTS PR00463 E-class P450 group I signature 391 414 6.1E-19 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4R43_12905 5af31adf4d58fbbd9ec5a25b7e5a16b8 264 Pfam PF00005 ABC transporter 22 169 2.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4R43_12905 5af31adf4d58fbbd9ec5a25b7e5a16b8 264 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4R43_12905 5af31adf4d58fbbd9ec5a25b7e5a16b8 264 Gene3D G3DSA:3.40.50.300 6 259 4.2E-72 T 14-10-2018 A4R43_12905 5af31adf4d58fbbd9ec5a25b7e5a16b8 264 SMART SM00382 30 219 5.1E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain A4R43_12905 5af31adf4d58fbbd9ec5a25b7e5a16b8 264 SUPERFAMILY SSF52540 5 233 2.45E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_09250 5610584fc75345251103a60ff277f45f 879 Pfam PF08665 PglZ domain 478 644 9.9E-10 T 14-10-2018 IPR013973 PglZ domain A4R43_01330 6bb416f587d1bfc2755b8e57eaa0313d 405 SUPERFAMILY SSF48371 63 347 1.73E-5 T 14-10-2018 IPR016024 Armadillo-type fold A4R43_01330 6bb416f587d1bfc2755b8e57eaa0313d 405 Gene3D G3DSA:1.25.10.10 143 274 2.8E-5 T 14-10-2018 IPR011989 Armadillo-like helical A4R43_01330 6bb416f587d1bfc2755b8e57eaa0313d 405 Gene3D G3DSA:1.25.10.10 1 132 4.5E-8 T 14-10-2018 IPR011989 Armadillo-like helical A4R43_18855 5a11983a4537cb8573cb873a2be320ce 334 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 295 9.9E-65 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_18855 5a11983a4537cb8573cb873a2be320ce 334 Pfam PF02470 MlaD protein 39 113 4.5E-16 T 14-10-2018 IPR003399 Mce/MlaD A4R43_19690 ae4e72258795de4fa9085bd328f5fdb4 152 Pfam PF11066 Protein of unknown function (DUF2867) 19 139 1.2E-5 T 14-10-2018 IPR021295 Protein of unknown function DUF2867 A4R43_25605 cabb2ef201f9f28a770329cdf5beecc5 236 Hamap MF_01384 Urease accessory protein UreD [ureD]. 1 231 17.187 T 14-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 A4R43_25605 cabb2ef201f9f28a770329cdf5beecc5 236 Pfam PF01774 UreD urease accessory protein 42 226 3.2E-23 T 14-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 A4R43_40875 feb2a6f3172ea1cb7ea6e627cbc3c15c 132 Pfam PF09656 Putative transmembrane protein (PGPGW) 3 54 2.8E-15 T 14-10-2018 IPR019099 Uncharacterised protein family PGPGW, transmembrane A4R43_35045 24808e7bc5e85dd3e632510739ed522e 127 Pfam PF08044 Domain of unknown function (DUF1707) 1 53 2.9E-19 T 14-10-2018 IPR012551 Protein of unknown function DUF1707 A4R43_24410 87747a1dd808606d73619f21bbac1d8c 267 Gene3D G3DSA:3.40.960.10 155 261 7.5E-7 T 14-10-2018 A4R43_16460 9f28b6b69d7d540b672e3fe6d7f17840 216 Gene3D G3DSA:2.70.70.10 31 207 2.5E-27 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_16460 9f28b6b69d7d540b672e3fe6d7f17840 216 SUPERFAMILY SSF51261 36 147 1.88E-16 T 14-10-2018 IPR011055 Duplicated hybrid motif A4R43_16460 9f28b6b69d7d540b672e3fe6d7f17840 216 Pfam PF01551 Peptidase family M23 60 146 1.1E-14 T 14-10-2018 IPR016047 Peptidase M23 A4R43_31370 1dd09a4ff214ff7fd4b10d1647a0189d 306 SUPERFAMILY SSF56601 14 295 6.76E-62 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_31370 1dd09a4ff214ff7fd4b10d1647a0189d 306 Gene3D G3DSA:3.40.710.10 6 303 2.8E-74 T 14-10-2018 A4R43_31370 1dd09a4ff214ff7fd4b10d1647a0189d 306 Pfam PF00144 Beta-lactamase 20 248 1.3E-45 T 14-10-2018 IPR001466 Beta-lactamase-related A4R43_00805 5cf7f3d426c71231b24c73cb82ad95b1 134 SUPERFAMILY SSF88723 32 128 1.11E-11 T 14-10-2018 IPR029060 PIN-like domain superfamily A4R43_00805 5cf7f3d426c71231b24c73cb82ad95b1 134 Gene3D G3DSA:3.40.50.1010 7 134 5.5E-21 T 14-10-2018 A4R43_13905 2b8a07669a8c1059ad6adafc8244ed65 549 Gene3D G3DSA:1.10.640.10 92 318 7.9E-15 T 14-10-2018 IPR037120 Haem peroxidase domain superfamily, animal type A4R43_13905 2b8a07669a8c1059ad6adafc8244ed65 549 SUPERFAMILY SSF48113 75 537 1.08E-57 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A4R43_13905 2b8a07669a8c1059ad6adafc8244ed65 549 Pfam PF03098 Animal haem peroxidase 116 295 9.0E-14 T 14-10-2018 IPR019791 Haem peroxidase, animal type A4R43_33255 f047ce643e8c179458a789a29c7a3f40 264 Pfam PF02274 Amidinotransferase 53 263 4.9E-13 T 14-10-2018 A4R43_33255 f047ce643e8c179458a789a29c7a3f40 264 SUPERFAMILY SSF55909 1 264 4.91E-51 T 14-10-2018 A4R43_33255 f047ce643e8c179458a789a29c7a3f40 264 Gene3D G3DSA:3.75.10.10 8 261 9.8E-55 T 14-10-2018 A4R43_11175 9813fb088aaa22638ebd75e29fdb0bf2 212 Pfam PF12079 Protein of unknown function (DUF3558) 17 206 2.0E-26 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_36315 1b105715cdcc53822b9eb2270ba7db0f 185 Pfam PF09438 Domain of unknown function (DUF2017) 6 183 7.1E-63 T 14-10-2018 IPR018561 Domain of unknown function DUF2017 A4R43_17355 c727966995eac6a142ae88c235f0799c 366 Pfam PF12706 Beta-lactamase superfamily domain 119 314 2.2E-50 T 14-10-2018 IPR001279 Metallo-beta-lactamase A4R43_17355 c727966995eac6a142ae88c235f0799c 366 Gene3D G3DSA:3.60.15.10 89 356 3.5E-84 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_17355 c727966995eac6a142ae88c235f0799c 366 SUPERFAMILY SSF56281 99 331 1.1E-35 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4R43_04315 7372ad281abfddcb79414b4bfede841b 173 Pfam PF14081 Domain of unknown function (DUF4262) 25 146 3.9E-33 T 14-10-2018 IPR025358 Protein of unknown function DUF4262 A4R43_35130 9732d9eb4e0f297cd9814ad1ebdc1a9a 72 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 6 65 2.0E-21 T 14-10-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit A4R43_24250 8773ae0f35833224d4070129b474f44f 104 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 2 98 2.6E-33 T 14-10-2018 IPR024534 Domain of unknown function DUF2220 A4R43_22595 086a69d15825e1353f25fc21f0f1ec5f 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 321 2.7E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_21705 ecd49fd2383993543eddbb1ad3e23b5e 687 SUPERFAMILY SSF52540 217 664 1.25E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_21705 ecd49fd2383993543eddbb1ad3e23b5e 687 Gene3D G3DSA:3.40.50.300 488 673 2.6E-17 T 14-10-2018 A4R43_21705 ecd49fd2383993543eddbb1ad3e23b5e 687 Gene3D G3DSA:3.40.50.300 207 346 5.0E-9 T 14-10-2018 A4R43_21705 ecd49fd2383993543eddbb1ad3e23b5e 687 Pfam PF01935 Domain of unknown function DUF87 216 322 7.0E-10 T 14-10-2018 IPR002789 Helicase HerA, central domain A4R43_16185 89e4cecb9dee57419e42567f06548952 126 Pfam PF04341 Protein of unknown function, DUF485 35 121 1.2E-31 T 14-10-2018 IPR007436 Protein of unknown function DUF485 A4R43_31990 2a62aee883deae5884733b20aa001729 348 Pfam PF02361 Cobalt transport protein 1 206 1.5E-12 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A4R43_37020 342adfa31eaa042195f88a443aba2ef6 272 SMART SM01043 121 266 1.6E-44 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37020 342adfa31eaa042195f88a443aba2ef6 272 Gene3D G3DSA:1.10.10.10 12 117 1.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_37020 342adfa31eaa042195f88a443aba2ef6 272 SUPERFAMILY SSF46894 22 114 4.54E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4R43_37020 342adfa31eaa042195f88a443aba2ef6 272 Pfam PF00486 Transcriptional regulatory protein, C terminal 41 114 2.4E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4R43_37020 342adfa31eaa042195f88a443aba2ef6 272 Gene3D G3DSA:1.25.40.10 119 272 2.2E-44 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_37020 342adfa31eaa042195f88a443aba2ef6 272 Pfam PF03704 Bacterial transcriptional activator domain 121 266 7.0E-40 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain A4R43_37020 342adfa31eaa042195f88a443aba2ef6 272 SUPERFAMILY SSF48452 116 268 2.04E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_23440 6c8c97ee36f687bd0d1d09a71132f63f 205 Pfam PF01810 LysE type translocator 14 197 2.9E-18 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4R43_35290 44bd23140f10dc2f83ebd30937c7eaae 450 Pfam PF09594 Glycosyltransferase family 87 99 341 4.0E-50 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_18050 11c6eeca1ea8ff008faea0dcd6c9b587 263 Pfam PF05552 Conserved TM helix 11 54 6.5E-12 T 14-10-2018 IPR008910 Conserved TM helix A4R43_18050 11c6eeca1ea8ff008faea0dcd6c9b587 263 Pfam PF05552 Conserved TM helix 101 145 1.4E-10 T 14-10-2018 IPR008910 Conserved TM helix A4R43_36660 99cd893948a9c397ab15a931e8b37d87 504 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 70 435 4.4E-12 T 14-10-2018 IPR021145 Portal protein A4R43_34440 57ce88731e4274d1aa92496a3f17eb0c 135 Pfam PF08044 Domain of unknown function (DUF1707) 11 63 1.7E-19 T 14-10-2018 IPR012551 Protein of unknown function DUF1707 A4R43_20065 6f6e899b3202ad0ecd55786e55d14394 344 Gene3D G3DSA:3.20.20.30 7 307 2.9E-62 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_20065 6f6e899b3202ad0ecd55786e55d14394 344 Pfam PF00296 Luciferase-like monooxygenase 12 193 2.2E-48 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4R43_20065 6f6e899b3202ad0ecd55786e55d14394 344 SUPERFAMILY SSF51679 12 296 1.83E-57 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A4R43_20065 6f6e899b3202ad0ecd55786e55d14394 344 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 4 306 1.0E-79 T 14-10-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted A4R43_40050 5bd86a5dcace7b22b2b60bab088f5c0a 183 SUPERFAMILY SSF46785 18 164 1.41E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40050 5bd86a5dcace7b22b2b60bab088f5c0a 183 Pfam PF12802 MarR family 56 108 8.9E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40050 5bd86a5dcace7b22b2b60bab088f5c0a 183 SMART SM00347 47 150 4.8E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_40050 5bd86a5dcace7b22b2b60bab088f5c0a 183 Gene3D G3DSA:1.10.10.10 7 165 2.3E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_19845 0b4a70ff41b8ce0082f9319ad2753e77 205 Gene3D G3DSA:3.40.50.150 2 198 1.1E-34 T 14-10-2018 A4R43_19845 0b4a70ff41b8ce0082f9319ad2753e77 205 Pfam PF08241 Methyltransferase domain 46 140 5.9E-22 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_19845 0b4a70ff41b8ce0082f9319ad2753e77 205 SUPERFAMILY SSF53335 3 162 4.85E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_27155 f228837e9e99dd700664aedb52f4cff0 195 Gene3D G3DSA:3.40.30.10 49 189 2.5E-18 T 14-10-2018 A4R43_27155 f228837e9e99dd700664aedb52f4cff0 195 Pfam PF00578 AhpC/TSA family 66 173 4.9E-8 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4R43_27155 f228837e9e99dd700664aedb52f4cff0 195 SUPERFAMILY SSF52833 48 176 1.52E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily A4R43_01810 5845d00ea9a744ac546d0dffcdcddfdc 456 Pfam PF03559 NDP-hexose 2,3-dehydratase 29 224 9.8E-67 T 14-10-2018 IPR005212 NDP-hexose 2,3-dehydratase KEGG: 00523+4.2.1.159 A4R43_01810 5845d00ea9a744ac546d0dffcdcddfdc 456 Pfam PF03559 NDP-hexose 2,3-dehydratase 257 455 8.6E-55 T 14-10-2018 IPR005212 NDP-hexose 2,3-dehydratase KEGG: 00523+4.2.1.159 A4R43_01810 5845d00ea9a744ac546d0dffcdcddfdc 456 Gene3D G3DSA:3.90.79.40 308 456 3.3E-38 T 14-10-2018 IPR038153 NDP-hexose 2,3-dehydratase-like superfamily KEGG: 00523+4.2.1.159 A4R43_01810 5845d00ea9a744ac546d0dffcdcddfdc 456 Gene3D G3DSA:3.90.79.40 80 231 1.2E-51 T 14-10-2018 IPR038153 NDP-hexose 2,3-dehydratase-like superfamily KEGG: 00523+4.2.1.159 A4R43_26555 4a791b4edce5c4f48ba9f76090498d05 212 Gene3D G3DSA:3.90.70.10 54 210 1.4E-6 T 14-10-2018 A4R43_26555 4a791b4edce5c4f48ba9f76090498d05 212 Pfam PF13529 Peptidase_C39 like family 47 186 9.5E-20 T 14-10-2018 IPR039564 Peptidase C39-like A4R43_26555 4a791b4edce5c4f48ba9f76090498d05 212 SUPERFAMILY SSF54001 43 206 4.9E-8 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_04185 084ee28c6792c282549c98ab05f3adf7 305 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 7 288 2.5E-67 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A4R43_17495 ce25ba5f4cbb5719827a60ac93b5ed30 376 Gene3D G3DSA:1.10.287.1060 20 107 2.6E-5 T 14-10-2018 A4R43_17495 ce25ba5f4cbb5719827a60ac93b5ed30 376 SUPERFAMILY SSF140453 21 108 9.94E-7 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_01770 5ac1ff23d909df4f02939a38546c78b5 298 SUPERFAMILY SSF48239 32 295 3.46E-10 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4R43_12910 7aa84da65c432b7a6e64224a49cf7746 349 SUPERFAMILY SSF81345 12 342 5.89E-62 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_12910 7aa84da65c432b7a6e64224a49cf7746 349 Gene3D G3DSA:1.10.3470.10 16 348 8.3E-83 T 14-10-2018 IPR037294 ABC transporter, BtuC-like A4R43_12910 7aa84da65c432b7a6e64224a49cf7746 349 Pfam PF01032 FecCD transport family 29 342 4.8E-75 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4R43_00180 3e4e72dae15414de5eeb63730c074a51 301 SUPERFAMILY SSF161098 61 289 1.23E-52 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_00180 3e4e72dae15414de5eeb63730c074a51 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 294 2.0E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_00180 3e4e72dae15414de5eeb63730c074a51 301 Gene3D G3DSA:1.10.3720.10 57 297 2.2E-61 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_27365 5efcec90638ac4f06ea945e62261f64b 305 Gene3D G3DSA:3.40.50.720 3 273 1.1E-39 T 14-10-2018 A4R43_27365 5efcec90638ac4f06ea945e62261f64b 305 Pfam PF00106 short chain dehydrogenase 8 211 3.5E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4R43_27365 5efcec90638ac4f06ea945e62261f64b 305 SUPERFAMILY SSF51735 5 263 2.59E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_35670 46baf73efd7bb0a91b8354c435fb25c0 136 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 5 83 7.1E-18 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 A4R43_35670 46baf73efd7bb0a91b8354c435fb25c0 136 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 131 14.41 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 A4R43_35670 46baf73efd7bb0a91b8354c435fb25c0 136 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 3.0E-9 T 14-10-2018 A4R43_35670 46baf73efd7bb0a91b8354c435fb25c0 136 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 3.0E-9 T 14-10-2018 A4R43_35670 46baf73efd7bb0a91b8354c435fb25c0 136 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 3.0E-9 T 14-10-2018 A4R43_35670 46baf73efd7bb0a91b8354c435fb25c0 136 Pfam PF02416 mttA/Hcf106 family 5 47 1.9E-6 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A4R43_28210 488e9b0d8869a60dec48ea06965840c0 323 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 31 305 1.6E-19 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A4R43_28015 abdb892855c30f52bec8091b71e82126 165 SUPERFAMILY SSF55729 3 155 1.21E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_28015 abdb892855c30f52bec8091b71e82126 165 Gene3D G3DSA:3.40.630.30 1 154 1.5E-14 T 14-10-2018 A4R43_21800 404f713c6b4c9e2739a1a56dfa92276a 270 SUPERFAMILY SSF81324 14 108 4.87E-9 T 14-10-2018 A4R43_21800 404f713c6b4c9e2739a1a56dfa92276a 270 Gene3D G3DSA:1.20.120.350 12 130 7.1E-20 T 14-10-2018 IPR027359 Voltage-dependent channel domain superfamily A4R43_24425 739e65d4229fb72cb08917b91ce89dac 656 SUPERFAMILY SSF52540 56 233 3.83E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_24425 739e65d4229fb72cb08917b91ce89dac 656 Gene3D G3DSA:3.40.50.300 73 180 4.1E-7 T 14-10-2018 A4R43_03695 452dfd5aba933e1c6bb579ec5ed6d499 168 SUPERFAMILY SSF55961 18 165 1.14E-20 T 14-10-2018 A4R43_03695 452dfd5aba933e1c6bb579ec5ed6d499 168 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 19 163 5.0E-15 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase A4R43_03695 452dfd5aba933e1c6bb579ec5ed6d499 168 Gene3D G3DSA:3.30.530.20 17 167 1.2E-35 T 14-10-2018 IPR023393 START-like domain superfamily A4R43_37800 3a1670fc0aabd3120887b1bb36e252bc 220 Gene3D G3DSA:2.30.30.40 34 109 3.1E-7 T 14-10-2018 A4R43_25615 e69e066228d16c8d52537c259beced23 221 Gene3D G3DSA:1.10.4190.10 2 191 2.7E-21 T 14-10-2018 IPR038277 UreF domain superfamily A4R43_25615 e69e066228d16c8d52537c259beced23 221 Pfam PF01730 UreF 33 171 3.9E-17 T 14-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 A4R43_39920 db0ea52cab5c99775a7038c5789fea09 316 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 81 312 3.2E-66 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A4R43_39920 db0ea52cab5c99775a7038c5789fea09 316 Gene3D G3DSA:3.90.850.10 67 313 5.5E-73 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_39920 db0ea52cab5c99775a7038c5789fea09 316 SUPERFAMILY SSF56529 77 315 4.06E-66 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A4R43_34035 671d03cfb0abd9db6e494ddfdf17e686 414 SUPERFAMILY SSF140453 92 169 3.92E-7 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_34035 671d03cfb0abd9db6e494ddfdf17e686 414 Gene3D G3DSA:1.10.287.1060 90 174 1.2E-8 T 14-10-2018 A4R43_34035 671d03cfb0abd9db6e494ddfdf17e686 414 Pfam PF06013 Proteins of 100 residues with WXG 93 167 9.2E-7 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like A4R43_06625 eaf8d818f3efcd8ec68c98dcde2e683f 158 SUPERFAMILY SSF53335 2 141 2.11E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_06625 eaf8d818f3efcd8ec68c98dcde2e683f 158 Gene3D G3DSA:3.40.50.150 1 154 5.7E-13 T 14-10-2018 A4R43_08515 be3619a23a44ee5e66ccb65a735090d7 303 Gene3D G3DSA:3.90.70.10 9 167 2.5E-5 T 14-10-2018 A4R43_32225 b585ddda9c445f8de71157f20947d14a 123 SUPERFAMILY SSF88659 86 122 3.49E-5 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4R43_38210 d476f5d547bb9ac293470245cddb7aca 178 Pfam PF12079 Protein of unknown function (DUF3558) 15 171 1.8E-11 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_35235 cb1499b678bdebd9e9e2b6016f1b7ecb 101 Gene3D G3DSA:1.10.287.1060 2 101 3.9E-6 T 14-10-2018 A4R43_35235 cb1499b678bdebd9e9e2b6016f1b7ecb 101 SUPERFAMILY SSF140453 4 100 1.14E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_23965 4d2a81b3e1dce162f7efd70a42319924 320 SUPERFAMILY SSF56601 61 247 8.25E-5 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4R43_17900 5dd08911dae36df57be8ae61414572bd 507 Pfam PF00561 alpha/beta hydrolase fold 77 448 5.2E-26 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_17900 5dd08911dae36df57be8ae61414572bd 507 SUPERFAMILY SSF53474 74 463 8.82E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_12550 3af140af7c300dc7355f04c9f57eb5bd 584 Pfam PF03068 Protein-arginine deiminase (PAD) 172 580 5.2E-75 T 14-10-2018 IPR013530 Protein-arginine deiminase, C-terminal GO:0004668|GO:0005509|GO:0005737 MetaCyc: PWY-4921|Reactome: R-HSA-3247509 A4R43_12550 3af140af7c300dc7355f04c9f57eb5bd 584 SUPERFAMILY SSF55909 220 579 1.37E-56 T 14-10-2018 A4R43_12550 3af140af7c300dc7355f04c9f57eb5bd 584 Gene3D G3DSA:3.75.10.10 214 583 1.8E-91 T 14-10-2018 A4R43_05250 ab74bbde46dbc992f68cfacf7076e426 175 Pfam PF12079 Protein of unknown function (DUF3558) 4 169 9.1E-15 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_19800 6f8afcd2606234102f8ced39ccb2016c 274 SUPERFAMILY SSF52518 5 270 1.18E-77 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold A4R43_19800 6f8afcd2606234102f8ced39ccb2016c 274 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 11 270 5.7E-44 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4R43_19800 6f8afcd2606234102f8ced39ccb2016c 274 Gene3D G3DSA:3.40.50.970 2 274 4.8E-86 T 14-10-2018 A4R43_30825 5accc110efc629bb240c34ff259c176f 134 Pfam PF17249 Family of unknown function (DUF5318) 1 128 7.2E-66 T 14-10-2018 IPR035169 Protein of unknown function DUF5318 A4R43_41290 9c67d7c14800cf6636d86e7475e8c42d 170 SUPERFAMILY SSF55729 8 126 1.11E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_41290 9c67d7c14800cf6636d86e7475e8c42d 170 Pfam PF00583 Acetyltransferase (GNAT) family 45 112 3.1E-12 T 14-10-2018 IPR000182 GNAT domain A4R43_41290 9c67d7c14800cf6636d86e7475e8c42d 170 Gene3D G3DSA:3.40.630.30 9 144 6.7E-26 T 14-10-2018 A4R43_20930 34e1a8b9c48f7ebb77883566e396a69d 123 Gene3D G3DSA:2.170.150.40 10 118 7.4E-39 T 14-10-2018 A4R43_20930 34e1a8b9c48f7ebb77883566e396a69d 123 Pfam PF04248 Domain of unknown function (DUF427) 25 113 4.7E-32 T 14-10-2018 IPR007361 Domain of unknown function DUF427 A4R43_33305 5a7ee6bb99be39db5e5c792a406bbbbb 138 Pfam PF12079 Protein of unknown function (DUF3558) 2 133 2.1E-19 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_20620 9b50cfa06d1190c6c8268c4283b60cba 237 Pfam PF13398 Peptidase M50B-like 24 226 2.9E-58 T 14-10-2018 A4R43_26570 2cff8cdc8a7d23626f597ce03d6a019f 256 SUPERFAMILY SSF110087 173 208 3.53E-5 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily A4R43_03575 e043810ec277e9fea185048c08cbe6ad 112 Gene3D G3DSA:2.30.110.10 9 107 6.3E-9 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4R43_03575 e043810ec277e9fea185048c08cbe6ad 112 Pfam PF04075 F420H(2)-dependent quinone reductase 19 76 1.3E-5 T 14-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 A4R43_33170 df7ec7845a946c2e38f9b34ffb799c86 346 SUPERFAMILY SSF140453 99 162 7.98E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_32080 45223b36b02dd5c66d716113c9ca5181 264 Pfam PF11209 Protein of unknown function (DUF2993) 8 249 2.3E-45 T 14-10-2018 IPR021373 Protein of unknown function DUF2993 A4R43_15810 2e2eccbab06a84b8df3aac44e6c9c4c1 305 Gene3D G3DSA:3.40.1790.10 1 305 1.2E-109 T 14-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A4R43_15810 2e2eccbab06a84b8df3aac44e6c9c4c1 305 SUPERFAMILY SSF110581 3 304 2.62E-94 T 14-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A4R43_15810 2e2eccbab06a84b8df3aac44e6c9c4c1 305 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 9 305 37.792 T 14-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A4R43_15810 2e2eccbab06a84b8df3aac44e6c9c4c1 305 Pfam PF04227 Indigoidine synthase A like protein 10 302 2.8E-109 T 14-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A4R43_21240 c14e5390c2638abf0a7f6e36416afb36 135 Gene3D G3DSA:3.10.180.10 2 135 4.9E-36 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_21240 c14e5390c2638abf0a7f6e36416afb36 135 SUPERFAMILY SSF54593 2 133 2.15E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4R43_21240 c14e5390c2638abf0a7f6e36416afb36 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 130 4.9E-15 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4R43_15215 02a40172d8b655e6cfc955e7d281ffe2 151 Pfam PF03780 Asp23 family, cell envelope-related function 24 134 1.6E-30 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 A4R43_41390 17688f9f46ddae4221d830269dce0007 123 Pfam PF12079 Protein of unknown function (DUF3558) 1 120 4.3E-13 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_29345 498f2464bf07559f1eda071c6ae8f54b 70 Pfam PF11146 Protein of unknown function (DUF2905) 9 67 1.1E-17 T 14-10-2018 IPR021320 Protein of unknown function DUF2905 A4R43_06175 78c080ac3b42b3e1478f7ffcd911eddc 127 Pfam PF17240 Family of unknown function (DUF5313) 3 125 8.8E-46 T 14-10-2018 IPR035197 Protein of unknown function DUF5313 A4R43_27750 2373f26cac40f5e6f4112772e2782cd3 141 SUPERFAMILY SSF55729 11 139 5.58E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_27750 2373f26cac40f5e6f4112772e2782cd3 141 Pfam PF00583 Acetyltransferase (GNAT) family 8 121 1.1E-15 T 14-10-2018 IPR000182 GNAT domain A4R43_27750 2373f26cac40f5e6f4112772e2782cd3 141 Gene3D G3DSA:3.40.630.30 5 141 2.8E-30 T 14-10-2018 A4R43_17945 de78b63c348e947b6a0da42472a0c07e 295 Pfam PF06089 L-asparaginase II 1 276 2.2E-101 T 14-10-2018 IPR010349 L-asparaginase II A4R43_15795 d737949c09f2073c61166887ca8eb78d 82 Pfam PF11238 Protein of unknown function (DUF3039) 20 76 4.9E-29 T 14-10-2018 IPR021400 Protein of unknown function DUF3039 A4R43_05775 5cc4ee7bbf9ec5374954c9b5365c9f7c 381 Pfam PF02720 Domain of unknown function (DUF222) 9 297 5.3E-11 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_35680 c9a6b6f48e8bcce4d2366a919b5a1456 170 Pfam PF06210 Protein of unknown function (DUF1003) 41 141 3.7E-39 T 14-10-2018 IPR010406 Protein of unknown function DUF1003 A4R43_26780 0f19527729ea7f53d1cc58ddb36a59e6 377 Pfam PF13367 Protease prsW family 58 255 6.8E-53 T 14-10-2018 IPR026898 Protease PrsW GO:0008233 A4R43_28070 ab43b276a5e151d8a721a5b7f7968441 316 Pfam PF01061 ABC-2 type transporter 39 277 3.8E-20 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_01415 a3bc4909c67826f82729fd6eec941de9 106 Gene3D G3DSA:1.10.287.1060 5 100 1.3E-5 T 14-10-2018 A4R43_01415 a3bc4909c67826f82729fd6eec941de9 106 SUPERFAMILY SSF140453 8 100 5.36E-6 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_01415 a3bc4909c67826f82729fd6eec941de9 106 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 8 98 4.2E-9 T 14-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 A4R43_25275 defe43d680c3ecf26e1c440111300090 488 Pfam PF13546 DDE superfamily endonuclease 22 269 1.3E-53 T 14-10-2018 IPR038721 Transposase IS701-like, DDE domain A4R43_25275 defe43d680c3ecf26e1c440111300090 488 SUPERFAMILY SSF53098 73 394 1.21E-9 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_12925 defe43d680c3ecf26e1c440111300090 488 Pfam PF13546 DDE superfamily endonuclease 22 269 1.3E-53 T 14-10-2018 IPR038721 Transposase IS701-like, DDE domain A4R43_12925 defe43d680c3ecf26e1c440111300090 488 SUPERFAMILY SSF53098 73 394 1.21E-9 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily A4R43_25780 edbd95ba2901c126ac13f84e62e147cc 412 Gene3D G3DSA:1.20.1250.20 2 388 5.7E-44 T 14-10-2018 A4R43_25780 edbd95ba2901c126ac13f84e62e147cc 412 Pfam PF05977 Transmembrane secretion effector 4 392 7.5E-55 T 14-10-2018 IPR010290 Transmembrane secretion effector A4R43_25780 edbd95ba2901c126ac13f84e62e147cc 412 SUPERFAMILY SSF103473 2 397 3.14E-47 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_18270 cbc02a9208c73648fe95f7de267165e7 125 Gene3D G3DSA:1.10.10.10 10 123 2.0E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_18270 cbc02a9208c73648fe95f7de267165e7 125 Pfam PF01638 HxlR-like helix-turn-helix 32 111 2.1E-22 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type A4R43_18270 cbc02a9208c73648fe95f7de267165e7 125 SUPERFAMILY SSF46785 17 120 2.66E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_40365 abb07f2909e1b5657e78132d1b17af77 422 Gene3D G3DSA:3.30.565.10 175 323 7.4E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_40365 abb07f2909e1b5657e78132d1b17af77 422 SUPERFAMILY SSF55874 198 324 4.32E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_32240 639a701b22002b050ba8210ab1538a3b 322 Pfam PF03756 A-factor biosynthesis hotdog domain 37 167 4.2E-27 T 14-10-2018 IPR005509 A-factor biosynthesis hotdog domain A4R43_32240 639a701b22002b050ba8210ab1538a3b 322 Pfam PF03756 A-factor biosynthesis hotdog domain 204 317 4.2E-14 T 14-10-2018 IPR005509 A-factor biosynthesis hotdog domain A4R43_14025 8ba8856ff0c81ea9bad523c1a5836af7 411 SUPERFAMILY SSF48452 48 157 3.8E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_14025 8ba8856ff0c81ea9bad523c1a5836af7 411 Gene3D G3DSA:1.25.40.10 20 189 2.4E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_00140 9884f7f0b0cf6c58cb202b4c0123ea2a 253 Pfam PF01925 Sulfite exporter TauE/SafE 7 246 5.9E-22 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A4R43_36330 a341a9abd17310c707aa77ace8cbcf63 92 Gene3D G3DSA:3.10.20.30 1 90 3.4E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily A4R43_36330 a341a9abd17310c707aa77ace8cbcf63 92 Pfam PF02597 ThiS family 5 90 1.7E-19 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A4R43_36330 a341a9abd17310c707aa77ace8cbcf63 92 SUPERFAMILY SSF54285 1 90 1.16E-23 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4R43_38810 3e6cd7cea3c5890498092d1260f45249 1028 SUPERFAMILY SSF48452 219 327 1.26E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4R43_14645 550164c789aa7c4d55be52f4292dfadc 192 SUPERFAMILY SSF46785 116 188 7.79E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_11780 f59ccd53babe9a768283d5ba6b2c0d8e 415 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 299 1.1E-49 T 14-10-2018 IPR005693 Virulence factor Mce protein A4R43_11780 f59ccd53babe9a768283d5ba6b2c0d8e 415 Pfam PF02470 MlaD protein 45 107 3.3E-10 T 14-10-2018 IPR003399 Mce/MlaD A4R43_20390 7052efa88de2a841d215b8c5220fd24f 258 PIRSF PIRSF006648 1 256 1.3E-57 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A4R43_20390 7052efa88de2a841d215b8c5220fd24f 258 Pfam PF01061 ABC-2 type transporter 10 219 6.6E-31 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4R43_08910 4f6aa7063e76790b343af8b897cea1c5 268 Pfam PF11296 Protein of unknown function (DUF3097) 6 263 3.9E-120 T 14-10-2018 IPR021447 Protein of unknown function DUF3097 A4R43_13845 e9e37d860e690457622c538ec8ef31fd 140 Pfam PF03994 Domain of Unknown Function (DUF350) 14 68 3.9E-16 T 14-10-2018 IPR007140 Protein of unknown function DUF350 A4R43_13845 e9e37d860e690457622c538ec8ef31fd 140 Pfam PF03994 Domain of Unknown Function (DUF350) 85 139 2.2E-14 T 14-10-2018 IPR007140 Protein of unknown function DUF350 A4R43_19695 1c6331540b27ffb6e7c99045282be246 182 Pfam PF06353 Protein of unknown function (DUF1062) 35 165 1.1E-39 T 14-10-2018 IPR009412 Protein of unknown function DUF1062 A4R43_33215 779d577299a246c5f07fe45a63760d81 204 Pfam PF12079 Protein of unknown function (DUF3558) 10 199 2.4E-24 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_31640 3d479477cec892a1ca21336967d7ebeb 212 SUPERFAMILY SSF46689 7 81 8.72E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31640 3d479477cec892a1ca21336967d7ebeb 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31640 3d479477cec892a1ca21336967d7ebeb 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_31640 3d479477cec892a1ca21336967d7ebeb 212 Gene3D G3DSA:1.10.357.10 3 203 2.1E-28 T 14-10-2018 A4R43_31640 3d479477cec892a1ca21336967d7ebeb 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 8.9E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4R43_14215 c4398edd2f824e98b87b821b843b9967 315 Pfam PF11382 Copper transport outer membrane protein, MctB 2 308 6.0E-98 T 14-10-2018 IPR021522 Copper transporter MctB GO:0016020|GO:0055070 A4R43_29035 79d0347f112d97c4f34052c09703aae0 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 267 2.5E-33 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_29035 79d0347f112d97c4f34052c09703aae0 273 Gene3D G3DSA:1.10.3720.10 57 263 5.4E-24 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_29035 79d0347f112d97c4f34052c09703aae0 273 SUPERFAMILY SSF161098 61 248 7.98E-28 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_29145 dcd8f6d9339ed805a55d91be662e360b 142 Pfam PF10756 Bacterial PH domain 62 139 4.9E-11 T 14-10-2018 IPR019692 Protein of unknown function DUF2581 A4R43_18805 8854acda0496dc4cdb726b30667819fe 331 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 90 114 8.3E-5 T 14-10-2018 A4R43_18805 8854acda0496dc4cdb726b30667819fe 331 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 163 187 7.5E-5 T 14-10-2018 A4R43_18805 8854acda0496dc4cdb726b30667819fe 331 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 277 304 9.5E-8 T 14-10-2018 A4R43_18805 8854acda0496dc4cdb726b30667819fe 331 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 238 267 2.3E-9 T 14-10-2018 A4R43_18805 8854acda0496dc4cdb726b30667819fe 331 Gene3D G3DSA:2.130.10.30 39 188 5.5E-37 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II A4R43_18805 8854acda0496dc4cdb726b30667819fe 331 Gene3D G3DSA:2.130.10.30 189 331 7.5E-44 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II A4R43_18805 8854acda0496dc4cdb726b30667819fe 331 SUPERFAMILY SSF50985 56 305 7.76E-45 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II A4R43_01485 0ad8b760c2d040b02d39460e1a980e82 136 Gene3D G3DSA:1.10.490.110 1 130 8.1E-17 T 14-10-2018 A4R43_01485 0ad8b760c2d040b02d39460e1a980e82 136 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 3 126 1.1E-34 T 14-10-2018 IPR018727 Protein of unknown function DUF2267 A4R43_37070 a637a9c83055eb9b9cb2ae2a9caa6141 641 Pfam PF07593 ASPIC and UnbV 562 620 2.1E-11 T 14-10-2018 IPR011519 ASPIC/UnbV A4R43_37070 a637a9c83055eb9b9cb2ae2a9caa6141 641 SUPERFAMILY SSF69318 71 538 3.14E-49 T 14-10-2018 A4R43_13650 4a823c3169fb41707f49cbf9312fd6db 454 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 59 439 1.6E-139 T 14-10-2018 IPR018721 Protein of unknown function DUF2252 A4R43_34135 96cf006139001fdd5cc879b41eff3787 102 Gene3D G3DSA:1.10.287.1060 3 96 2.1E-6 T 14-10-2018 A4R43_34135 96cf006139001fdd5cc879b41eff3787 102 SUPERFAMILY SSF140453 5 98 2.35E-7 T 14-10-2018 IPR036689 ESAT-6-like superfamily A4R43_19435 d9d50947bd1f2d2280de9a1741d5059b 102 Pfam PF02656 Domain of unknown function (DUF202) 4 67 2.5E-11 T 14-10-2018 IPR003807 Domain of unknown function DUF202 A4R43_18430 b0b727ed9d366e0f4c68349fc47d8e8c 107 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 4.5E-53 T 14-10-2018 IPR019592 Protein of unknown function DUF2469 A4R43_35985 5c8582f0bdc3d7285006f5ac37e1f47e 211 Pfam PF13559 Domain of unknown function (DUF4129) 123 193 1.2E-15 T 14-10-2018 IPR025403 Domain of unknown function DUF4129 A4R43_25740 412d9485fb94742ae1c9b203dd341abb 188 Pfam PF10801 Protein of unknown function (DUF2537) 104 183 3.3E-23 T 14-10-2018 IPR024244 Protein of unknown function DUF2537 A4R43_39990 4115b57d299178b2c55a258851587e5d 493 SUPERFAMILY SSF47781 409 475 4.0E-8 T 14-10-2018 IPR010994 RuvA domain 2-like A4R43_39990 4115b57d299178b2c55a258851587e5d 493 Pfam PF12836 Helix-hairpin-helix motif 418 473 3.3E-6 T 14-10-2018 A4R43_10190 1bab44eaa4a6e8248da58c5e96ff33f9 824 Pfam PF02687 FtsX-like permease family 275 371 1.6E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_24760 0acd39f15741c920790c6e5f27eec5a6 99 Gene3D G3DSA:1.10.10.10 5 89 1.4E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4R43_24760 0acd39f15741c920790c6e5f27eec5a6 99 Pfam PF12802 MarR family 9 59 1.9E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4R43_24760 0acd39f15741c920790c6e5f27eec5a6 99 SUPERFAMILY SSF46785 9 65 9.64E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4R43_29405 da2f24b4307ba5c2ed21a5472a265161 177 SUPERFAMILY SSF55874 47 129 9.72E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_29405 da2f24b4307ba5c2ed21a5472a265161 177 Gene3D G3DSA:3.30.565.10 17 138 1.5E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4R43_26115 830d4b5277c8b246dd170e8e741103b3 219 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 121 211 4.4E-13 T 14-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4R43_26115 830d4b5277c8b246dd170e8e741103b3 219 Gene3D G3DSA:3.30.70.2390 120 209 1.0E-30 T 14-10-2018 A4R43_27765 3451e5354f5e28f390f6f932cfc3b119 205 PIRSF PIRSF020606 1 200 9.6E-63 T 14-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 A4R43_27765 3451e5354f5e28f390f6f932cfc3b119 205 Pfam PF09997 Predicted membrane protein (DUF2238) 38 177 3.3E-51 T 14-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 A4R43_39150 41b3ee986252ec3274612500014aa486 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 306 5.3E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_01905 c4072c14f78e21bde34fe246c4b7ca56 208 Gene3D G3DSA:3.40.50.720 4 142 1.3E-20 T 14-10-2018 A4R43_01905 c4072c14f78e21bde34fe246c4b7ca56 208 SUPERFAMILY SSF51735 8 141 2.63E-18 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily A4R43_01905 c4072c14f78e21bde34fe246c4b7ca56 208 Pfam PF02254 TrkA-N domain 8 126 3.4E-19 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4R43_04035 2493bb5debec53c66f7da68f98212f79 255 SUPERFAMILY SSF51621 6 252 2.43E-64 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4R43_04035 2493bb5debec53c66f7da68f98212f79 255 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 240 5.2E-37 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4R43_04035 2493bb5debec53c66f7da68f98212f79 255 Gene3D G3DSA:3.20.20.60 2 254 1.4E-71 T 14-10-2018 A4R43_05845 ff9b9b7b5083179300078815db6ff293 281 Pfam PF14339 Domain of unknown function (DUF4394) 43 273 8.8E-61 T 14-10-2018 IPR025507 Domain of unknown function DUF4394 A4R43_35840 84310a1550ec8fee22e5b78d26556abd 417 Pfam PF07786 Protein of unknown function (DUF1624) 28 194 1.5E-6 T 14-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 A4R43_35840 84310a1550ec8fee22e5b78d26556abd 417 Pfam PF04235 Protein of unknown function (DUF418) 297 405 4.8E-7 T 14-10-2018 IPR007349 Domain of unknown function DUF418 A4R43_26240 cde1ac4c5b40b6cee97f47943d284e32 238 Pfam PF14011 EspG family 13 229 1.8E-28 T 14-10-2018 IPR025734 EspG family A4R43_39975 b58903fd4f44f2a44be6d11d9a7a7a56 71 Pfam PF11211 Protein of unknown function (DUF2997) 6 51 1.1E-15 T 14-10-2018 IPR021375 Protein of unknown function DUF2997 A4R43_21170 c487a957c6a180b84e58ed4274f4c5bf 272 SUPERFAMILY SSF47090 56 116 7.85E-6 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_21170 c487a957c6a180b84e58ed4274f4c5bf 272 Gene3D G3DSA:1.10.101.10 50 127 3.5E-6 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_35270 b9d4a864c41f47700282f0d5772f9167 186 Pfam PF04138 GtrA-like protein 27 157 1.0E-23 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4R43_41585 2dcbafee1c9139dc921be0c6717e3ac4 248 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 3 235 1.3E-72 T 14-10-2018 IPR012666 Cobalt transporter subunit CbtA, putative A4R43_29210 29add6d58385269c0488f561367b5a02 404 SUPERFAMILY SSF54001 268 379 5.89E-9 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4R43_33005 59df989d24ccf866e75ad5d9b02b7e1f 95 Pfam PF14012 Protein of unknown function (DUF4229) 16 76 2.9E-14 T 14-10-2018 IPR025323 Protein of unknown function DUF4229 A4R43_36715 cdc411216f2c856369bc78c4780e31a2 1170 SUPERFAMILY SSF58104 534 762 7.06E-5 T 14-10-2018 A4R43_13800 ce6b97ba1ecfc53b2c8f6967df043c09 266 SUPERFAMILY SSF51658 23 210 1.91E-16 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_13800 ce6b97ba1ecfc53b2c8f6967df043c09 266 Gene3D G3DSA:3.20.20.150 2 265 6.7E-83 T 14-10-2018 A4R43_13800 ce6b97ba1ecfc53b2c8f6967df043c09 266 Pfam PF05114 Protein of unknown function (DUF692) 5 264 2.0E-83 T 14-10-2018 IPR007801 Uncharacterised protein family UPF0276 A4R43_34765 c0cedb16fb09a6c97a99ced9c8e89fa6 413 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 337 4.7E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_01150 dac22c25fc5e39b30ecb060f66c7d60d 329 Pfam PF17236 Family of unknown function (DUF5309) 22 318 1.9E-47 T 14-10-2018 IPR035198 Protein of unknown function DUF5309 A4R43_16825 f756dd70650f0d27a812c82b0fdd9110 337 SUPERFAMILY SSF101898 38 270 8.63E-11 T 14-10-2018 A4R43_26660 af5f5fba4ece0891441761b19db6022e 437 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 151 367 3.4E-22 T 14-10-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain A4R43_28935 51fa7d216b42cc9cc7ac47c2826b586b 413 Pfam PF13347 MFS/sugar transport protein 57 354 1.3E-21 T 14-10-2018 A4R43_28935 51fa7d216b42cc9cc7ac47c2826b586b 413 Gene3D G3DSA:1.20.1250.20 16 411 1.1E-43 T 14-10-2018 A4R43_28935 51fa7d216b42cc9cc7ac47c2826b586b 413 SUPERFAMILY SSF103473 20 410 2.22E-47 T 14-10-2018 IPR036259 MFS transporter superfamily A4R43_01455 4c7fe316aa72c055e015bfe077aff8b8 386 Pfam PF04230 Polysaccharide pyruvyl transferase 15 311 2.6E-13 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase A4R43_33755 210c3ca847b3967a368a56e02e065cb6 341 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 328 8.6E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_35660 331a67c33814435963ac3eb5714b7ed5 218 Pfam PF13490 Putative zinc-finger 18 46 2.8E-5 T 14-10-2018 IPR027383 Putative zinc-finger A4R43_35660 331a67c33814435963ac3eb5714b7ed5 218 Gene3D G3DSA:1.10.10.1320 10 101 1.2E-5 T 14-10-2018 A4R43_02140 a8d196f6f9b002736818fd4eb43b931c 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 2.2E-129 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A4R43_04475 c3286d9f056044348a76b4a46d29cd7c 383 SUPERFAMILY SSF56112 30 309 5.51E-12 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily A4R43_14655 a91cc1ce22e0372ea9fcc38f10d6717f 218 Pfam PF08808 RES domain 32 196 3.1E-20 T 14-10-2018 IPR014914 RES domain A4R43_14655 a91cc1ce22e0372ea9fcc38f10d6717f 218 SMART SM00953 54 190 3.6E-5 T 14-10-2018 IPR014914 RES domain A4R43_01450 83ecf3ff9d9bd5add4c97c80017e90bc 216 SUPERFAMILY SSF53597 30 213 1.64E-21 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_01450 83ecf3ff9d9bd5add4c97c80017e90bc 216 Gene3D G3DSA:3.40.430.10 29 210 1.1E-24 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4R43_01450 83ecf3ff9d9bd5add4c97c80017e90bc 216 Pfam PF01872 RibD C-terminal domain 30 203 2.7E-16 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4R43_07960 484d87b26f9b46c697b376fa6baef99f 392 Pfam PF15892 BNR repeat-containing family member 25 285 3.4E-43 T 14-10-2018 IPR039469 BNR repeat-containing family member A4R43_40495 9fe10de313aa91d75a5f83ab101f8183 100 Gene3D G3DSA:1.10.287.1060 1 91 2.3E-5 T 14-10-2018 A4R43_27675 9dba90e1424636a57b1f2760da5583bc 233 Gene3D G3DSA:3.40.50.1110 48 233 7.8E-23 T 14-10-2018 IPR036514 SGNH hydrolase superfamily A4R43_27675 9dba90e1424636a57b1f2760da5583bc 233 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 51 225 1.2E-18 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4R43_27675 9dba90e1424636a57b1f2760da5583bc 233 SUPERFAMILY SSF52266 46 231 6.41E-27 T 14-10-2018 A4R43_00430 f5da0597e52cca65a0ca6a204a539458 319 Pfam PF01261 Xylose isomerase-like TIM barrel 43 256 4.8E-28 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4R43_00430 f5da0597e52cca65a0ca6a204a539458 319 SUPERFAMILY SSF51658 21 312 6.15E-43 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily A4R43_00430 f5da0597e52cca65a0ca6a204a539458 319 Gene3D G3DSA:3.20.20.150 7 315 8.4E-91 T 14-10-2018 A4R43_16265 7809e10dbea612c6d71ab5363f27014f 132 SUPERFAMILY SSF55298 6 132 8.95E-33 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_16265 7809e10dbea612c6d71ab5363f27014f 132 Gene3D G3DSA:3.30.1330.40 4 132 4.2E-37 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4R43_16265 7809e10dbea612c6d71ab5363f27014f 132 Pfam PF01042 Endoribonuclease L-PSP 16 130 4.8E-26 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4R43_30395 bf0253b3c45d50314208206e289fc4b1 265 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 145 263 2.9E-43 T 14-10-2018 IPR021949 Domain of unknown function DUF3566. transmembrane A4R43_13330 693cff87b95455168c20f1771e748577 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 8.4E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13330 693cff87b95455168c20f1771e748577 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 8.4E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13330 693cff87b95455168c20f1771e748577 262 Pfam PF00561 alpha/beta hydrolase fold 24 143 1.1E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_13330 693cff87b95455168c20f1771e748577 262 SUPERFAMILY SSF53474 3 262 2.7E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_13330 693cff87b95455168c20f1771e748577 262 Gene3D G3DSA:3.40.50.1820 3 262 9.4E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_14035 ec8cd5f995f4db6a1fd1852e62a2a150 125 Gene3D G3DSA:2.40.50.140 37 125 3.6E-5 T 14-10-2018 A4R43_14035 ec8cd5f995f4db6a1fd1852e62a2a150 125 PIRSF PIRSF006910 1 124 4.5E-54 T 14-10-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted A4R43_30735 c658603ec897e898ce8bcc3582878815 264 Pfam PF14011 EspG family 22 256 1.2E-40 T 14-10-2018 IPR025734 EspG family A4R43_29500 a88d6fca484a8d2c68a62ff81e50914c 327 SUPERFAMILY SSF53167 121 321 3.4E-12 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A4R43_22095 c0215a742e066b769e08b233a8b49a6e 242 Pfam PF13829 Domain of unknown function (DUF4191) 19 233 6.5E-85 T 14-10-2018 IPR025445 Protein of unknown function DUF4191 A4R43_22095 c0215a742e066b769e08b233a8b49a6e 242 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 27 227 4.0E-70 T 14-10-2018 A4R43_41335 e30f7dffa4aee73c71d99db2716d21a0 189 SUPERFAMILY SSF55729 5 178 6.67E-46 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4R43_41335 e30f7dffa4aee73c71d99db2716d21a0 189 Gene3D G3DSA:3.40.630.30 6 187 1.3E-50 T 14-10-2018 A4R43_41335 e30f7dffa4aee73c71d99db2716d21a0 189 Pfam PF13302 Acetyltransferase (GNAT) domain 12 154 2.2E-31 T 14-10-2018 IPR000182 GNAT domain A4R43_25830 4004a8968a218176c98d769a45c05443 165 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 26 89 1.0E-6 T 14-10-2018 IPR024495 Protein of unknown function DUF2771 A4R43_25830 4004a8968a218176c98d769a45c05443 165 Pfam PF10969 Protein of unknown function (DUF2771) 22 134 8.3E-22 T 14-10-2018 IPR024495 Protein of unknown function DUF2771 A4R43_16230 d931e54aaf22083bfd931a0efc2ff013 275 Gene3D G3DSA:1.10.530.10 114 273 2.0E-8 T 14-10-2018 A4R43_16230 d931e54aaf22083bfd931a0efc2ff013 275 SUPERFAMILY SSF53955 99 266 2.11E-33 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily A4R43_26830 72b6872e87a34057aa11fd2b3d72d68c 266 Pfam PF14011 EspG family 8 251 4.7E-65 T 14-10-2018 IPR025734 EspG family A4R43_31740 d42885028126ae49f8fbea141755125a 113 Pfam PF13564 DoxX-like family 5 104 5.7E-16 T 14-10-2018 IPR032808 DoxX family A4R43_32665 f2adeb07c35d7928c86fe2adb1d46c64 118 Pfam PF13453 Transcription factor zinc-finger 1 32 1.1E-10 T 14-10-2018 IPR027392 Transcription factor zinc-finger A4R43_40130 a5f0d05a41e825aaeb98388c0ec77e08 513 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 66 227 4.2E-19 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4R43_12530 ccbdf6a95a2fd13058b27552d583cf2d 286 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 10 216 5.5E-16 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A4R43_11810 c159ec249caa025599e960bd0a993880 283 Pfam PF02405 Permease MlaE 64 269 1.2E-55 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_29105 645e15f5f0c3c8996dd642dc4db24b9a 482 Pfam PF01098 Cell cycle protein 87 453 3.0E-91 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4R43_05685 dd7464810315ba46eba0ca99d822e3da 90 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 85 17.092 T 14-10-2018 IPR003482 Transcription factor WhiB A4R43_05685 dd7464810315ba46eba0ca99d822e3da 90 Pfam PF02467 Transcription factor WhiB 12 80 1.9E-23 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain A4R43_29320 afdca458a17bac9e944a0cdfbd29e186 105 Gene3D G3DSA:1.10.490.110 12 99 2.2E-6 T 14-10-2018 A4R43_29320 afdca458a17bac9e944a0cdfbd29e186 105 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 15 95 2.6E-16 T 14-10-2018 IPR018727 Protein of unknown function DUF2267 A4R43_29180 4b3bddc50db973dfdeb86df602c0fb4d 147 Pfam PF14081 Domain of unknown function (DUF4262) 16 135 2.3E-27 T 14-10-2018 IPR025358 Protein of unknown function DUF4262 A4R43_02300 91f661371e5877243c2793f53c52a325 336 Pfam PF00487 Fatty acid desaturase 58 300 3.6E-34 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A4R43_23160 9545f0d92b30dd2e604fade5ac817ac9 256 Gene3D G3DSA:3.90.1680.10 1 238 3.8E-69 T 14-10-2018 IPR036590 SOS response associated peptidase-like A4R43_23160 9545f0d92b30dd2e604fade5ac817ac9 256 Pfam PF02586 SOS response associated peptidase (SRAP) 1 228 2.3E-69 T 14-10-2018 IPR003738 SOS response associated peptidase (SRAP) A4R43_23160 9545f0d92b30dd2e604fade5ac817ac9 256 SUPERFAMILY SSF143081 2 237 1.11E-64 T 14-10-2018 IPR036590 SOS response associated peptidase-like A4R43_23625 ca5538a6441ddc731e11f982d9943e08 225 Pfam PF03006 Haemolysin-III related 16 216 5.8E-40 T 14-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 A4R43_23625 ca5538a6441ddc731e11f982d9943e08 225 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 18 222 1.8E-57 T 14-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 A4R43_16380 872a3a6846152c3f96888e763b0b915d 262 Pfam PF00149 Calcineurin-like phosphoesterase 1 233 2.9E-9 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4R43_16380 872a3a6846152c3f96888e763b0b915d 262 SUPERFAMILY SSF56300 1 253 3.04E-31 T 14-10-2018 A4R43_18845 879b036d0f8ef1d1dd7400971c141f6b 286 Pfam PF02405 Permease MlaE 69 273 2.6E-59 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_28390 6eb57bcb4405a2f2eac2a68714d2a03d 156 Pfam PF06803 Protein of unknown function (DUF1232) 66 100 2.0E-10 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 A4R43_36020 e8df12d088835635082c09fb4824f377 425 Pfam PF09972 Predicted membrane protein (DUF2207) 22 396 2.1E-19 T 14-10-2018 IPR018702 Protein of unknown function DUF2207, membrane A4R43_27135 54599eb5d4c83ce40479cb3bed34e198 163 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 35 149 1.5E-33 T 14-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III A4R43_25220 3302b1835c1278cc0ddc742f8bc136cc 520 Gene3D G3DSA:3.40.50.300 256 510 2.7E-31 T 14-10-2018 A4R43_25220 3302b1835c1278cc0ddc742f8bc136cc 520 SUPERFAMILY SSF52540 245 498 3.72E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4R43_25220 3302b1835c1278cc0ddc742f8bc136cc 520 Pfam PF01580 FtsK/SpoIIIE family 278 360 3.9E-7 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4R43_25170 02833d2bedf9f7fd4fcc691baff390d6 306 Gene3D G3DSA:2.40.420.20 226 304 1.4E-12 T 14-10-2018 A4R43_25170 02833d2bedf9f7fd4fcc691baff390d6 306 SUPERFAMILY SSF47090 63 122 4.08E-11 T 14-10-2018 IPR036365 PGBD-like superfamily A4R43_25170 02833d2bedf9f7fd4fcc691baff390d6 306 Pfam PF01471 Putative peptidoglycan binding domain 75 122 3.4E-10 T 14-10-2018 IPR002477 Peptidoglycan binding-like A4R43_25170 02833d2bedf9f7fd4fcc691baff390d6 306 Gene3D G3DSA:1.10.101.10 61 125 2.9E-11 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4R43_05210 621777a82cedd2f6743d06a360e5a05c 563 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 7 335 2.1E-130 T 14-10-2018 IPR010839 Acyclic terpene utilisation A4R43_20740 6bfb9aa1e9b06ad1fcdda6a0d7a4e7f5 346 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 21 309 4.7E-32 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A4R43_22550 61a7ca110cdbab7391ceaad42becfdc7 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 311 1.8E-44 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_24490 0261373e63c3cf37f82d1443a1b169b2 126 Pfam PF17240 Family of unknown function (DUF5313) 8 123 1.6E-20 T 14-10-2018 IPR035197 Protein of unknown function DUF5313 A4R43_24505 60215702c141b070b1d2c52f90a5bf21 220 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 22 182 1.0E-17 T 14-10-2018 A4R43_00495 7a5af3d843c9d9dffa02b0be5c548db1 199 Gene3D G3DSA:1.10.357.10 1 197 1.2E-15 T 14-10-2018 A4R43_00495 7a5af3d843c9d9dffa02b0be5c548db1 199 SUPERFAMILY SSF46689 3 66 4.93E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_31285 cffd6eb87486989abdd2d2f11161bacf 400 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 114 346 3.7E-41 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 A4R43_21265 ec6582930eb5b75066771905c7956144 207 Gene3D G3DSA:3.90.79.10 2 129 2.9E-21 T 14-10-2018 A4R43_21265 ec6582930eb5b75066771905c7956144 207 SUPERFAMILY SSF55811 7 134 1.96E-16 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4R43_10360 e2fff60c5e6d94703c59f212690e5d27 315 Pfam PF01136 Peptidase family U32 132 218 7.0E-8 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A4R43_20410 80a6891972e6e310721bf8f42fa07035 392 Gene3D G3DSA:3.40.50.150 84 255 6.8E-33 T 14-10-2018 A4R43_20410 80a6891972e6e310721bf8f42fa07035 392 SUPERFAMILY SSF53335 82 203 1.46E-13 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_04400 6cdb522d26ca7311d1c382f44bfb065c 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 314 1.7E-36 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4R43_04400 6cdb522d26ca7311d1c382f44bfb065c 320 SUPERFAMILY SSF161098 94 297 2.75E-19 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_04400 6cdb522d26ca7311d1c382f44bfb065c 320 Gene3D G3DSA:1.10.3720.10 87 308 1.8E-23 T 14-10-2018 IPR035906 MetI-like superfamily A4R43_30610 3aa737a2ed610fa7947d257db6fc7068 338 Pfam PF13449 Esterase-like activity of phytase 46 324 2.3E-71 T 14-10-2018 IPR027372 Phytase-like domain A4R43_30610 3aa737a2ed610fa7947d257db6fc7068 338 SUPERFAMILY SSF50956 37 245 9.02E-6 T 14-10-2018 A4R43_39295 32723bbfbc9374ef9f78cb69791881ec 629 Pfam PF02687 FtsX-like permease family 95 190 1.7E-7 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4R43_39070 7e3cd784c2977de6ab3e73c6bd61c075 290 Gene3D G3DSA:3.40.50.1820 49 284 3.9E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_39070 7e3cd784c2977de6ab3e73c6bd61c075 290 Pfam PF00756 Putative esterase 54 224 2.5E-6 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A4R43_39070 7e3cd784c2977de6ab3e73c6bd61c075 290 SUPERFAMILY SSF53474 45 284 1.05E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_11380 b8bf3181de2e453d8162cf7a735d0fc4 309 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 15 248 1.2E-54 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 A4R43_40350 d7189f0df0b24f9865840771aa8b4496 230 Gene3D G3DSA:3.40.109.10 12 229 3.2E-54 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_40350 d7189f0df0b24f9865840771aa8b4496 230 SUPERFAMILY SSF55469 32 228 5.5E-41 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4R43_40350 d7189f0df0b24f9865840771aa8b4496 230 Pfam PF00881 Nitroreductase family 40 208 1.1E-19 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4R43_11905 a556bc0a133d1f755628c86e9a78e73a 361 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 332 1.4E-42 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_39790 764d5283f75131b179f9bca6411617e2 217 Pfam PF02698 DUF218 domain 50 195 2.0E-23 T 14-10-2018 IPR003848 Domain of unknown function DUF218 A4R43_26060 e25f3a5e5b787d17f15529ff9084b410 72 Pfam PF04024 PspC domain 11 68 1.9E-18 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A4R43_13625 2b7923a4cc2a4ea3f1c6f859a525613f 111 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 106 3.3E-24 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4R43_13625 2b7923a4cc2a4ea3f1c6f859a525613f 111 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 111 16.945 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4R43_13700 8d628152713245a7d3f50d1a60622a36 129 Pfam PF03780 Asp23 family, cell envelope-related function 21 118 1.6E-13 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 A4R43_16885 af58c9e51b60d0ae4556b9a3d0fd0447 74 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 39 4.9E-5 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A4R43_35770 fa4a898d95f61c722cc96be6084605bb 167 Pfam PF01575 MaoC like domain 12 118 1.3E-15 T 14-10-2018 IPR002539 MaoC-like dehydratase domain A4R43_35770 fa4a898d95f61c722cc96be6084605bb 167 Gene3D G3DSA:3.10.129.10 1 150 1.6E-45 T 14-10-2018 A4R43_35770 fa4a898d95f61c722cc96be6084605bb 167 SUPERFAMILY SSF54637 2 151 1.12E-45 T 14-10-2018 IPR029069 HotDog domain superfamily A4R43_11700 a596bfca415e2faee5a2a60524e957d8 255 Pfam PF05331 Protein of unknown function (DUF742) 147 255 1.8E-33 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_14885 73b394c52ce651c47ebb8737ce550907 374 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 327 6.6E-47 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_07610 76081eb70689572088e73332fd537b02 287 Pfam PF03780 Asp23 family, cell envelope-related function 221 281 6.1E-9 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 A4R43_21350 c2648c97f1f4e3bf28c73c0ba40ead81 95 Pfam PF14117 Domain of unknown function (DUF4287) 2 64 2.7E-26 T 14-10-2018 IPR025629 Protein of unknown function DUF4287 A4R43_28275 8c2dad8f8fe035ebc77eabb9875e893d 241 Gene3D G3DSA:1.10.287.470 132 183 8.1E-6 T 14-10-2018 A4R43_24850 7a75a00b3376f4cc5643c552ec1ac27c 410 Pfam PF12666 PrgI family protein 3 82 1.2E-13 T 14-10-2018 IPR024414 Uncharacterised protein family PrgI A4R43_05675 d3c0adf4feda99465222f8ee59ef3aff 221 SUPERFAMILY SSF49482 66 219 1.16E-43 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4R43_05675 d3c0adf4feda99465222f8ee59ef3aff 221 Gene3D G3DSA:2.60.130.10 64 220 3.0E-56 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4R43_05675 d3c0adf4feda99465222f8ee59ef3aff 221 Pfam PF00775 Dioxygenase 74 219 5.2E-19 T 14-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 A4R43_21845 8d2315b9482ee67ea0be6822fc010230 237 Gene3D G3DSA:3.40.50.1820 4 233 2.7E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_21845 8d2315b9482ee67ea0be6822fc010230 237 SUPERFAMILY SSF53474 4 232 4.02E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_21845 8d2315b9482ee67ea0be6822fc010230 237 Pfam PF01738 Dienelactone hydrolase family 16 232 7.4E-28 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 A4R43_02090 8c699cbcda072f72de4d95176bcbfb15 430 TIGRFAM TIGR00784 citMHS: citrate transporter 1 430 4.6E-138 T 14-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 A4R43_02090 8c699cbcda072f72de4d95176bcbfb15 430 Pfam PF03600 Citrate transporter 13 373 1.1E-43 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A4R43_17615 e8b2c1f2f126bf579014c000ea93000c 153 Pfam PF13787 Protein of unknown function with HXXEE motif 10 105 3.4E-16 T 14-10-2018 IPR025671 Protein of unknown function with HXXEE motif A4R43_18930 3ecd75febfd794d6c566ba7b170c0de7 290 SUPERFAMILY SSF50199 37 198 2.88E-7 T 14-10-2018 A4R43_32730 a020c789dffe99b42d6846979185637c 165 Pfam PF10698 Protein of unknown function (DUF2505) 6 162 6.2E-44 T 14-10-2018 IPR019639 Protein of unknown function DUF2505 A4R43_26745 4cf71c8205c982ab98c63cbbd932eed8 251 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 225 245 5.6E-6 T 14-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 A4R43_14070 6dcdd9cf4939caf82c20a228b471c506 225 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 81 170 1.6E-10 T 14-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4R43_17670 86e3288500b612e1a0355f594534890f 440 Pfam PF05991 YacP-like NYN domain 320 437 2.1E-19 T 14-10-2018 IPR010298 Protein of unknown function DUF901 A4R43_20945 3080491e53f34e3969f0aeee0150e3c2 113 Pfam PF05331 Protein of unknown function (DUF742) 3 111 5.1E-31 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_14050 7d42ea7394d9d4ec1e5f0dee6b183070 225 Pfam PF12502 Protein of unknown function (DUF3710) 48 216 1.3E-58 T 14-10-2018 IPR022183 Protein of unknown function DUF3710 A4R43_15220 ee47628220fe385b3f0f3f80c911bfd1 110 Pfam PF03780 Asp23 family, cell envelope-related function 4 98 3.7E-12 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 A4R43_40140 da5588a76c1de0a9cad3f2298cb22f4d 448 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 438 1.5E-45 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A4R43_24625 e4c1397a8f1bdcdde41c741bca0f797c 259 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 12 251 2.8E-51 T 14-10-2018 IPR005226 UPF0014 family A4R43_24625 e4c1397a8f1bdcdde41c741bca0f797c 259 Pfam PF03649 Uncharacterised protein family (UPF0014) 11 246 7.4E-63 T 14-10-2018 IPR005226 UPF0014 family A4R43_30660 c2e721e099793236cd15ee3798ad7421 197 Pfam PF08044 Domain of unknown function (DUF1707) 1 51 1.2E-19 T 14-10-2018 IPR012551 Protein of unknown function DUF1707 A4R43_08430 5b3dd8d0ecf0fbc0a1e51b42c5e1288f 176 Pfam PF14136 Domain of unknown function (DUF4303) 18 165 3.2E-38 T 14-10-2018 IPR025409 Protein of unknown function DUF4303 A4R43_18470 a40f5fa68abc3d9340ffc54bd8041cd9 252 Pfam PF02517 CAAX protease self-immunity 144 237 6.0E-14 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A4R43_35820 9a48cf1cd0ab149577135b75af6fd9bb 389 SUPERFAMILY SSF50998 39 370 9.42E-9 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4R43_35820 9a48cf1cd0ab149577135b75af6fd9bb 389 Gene3D G3DSA:2.130.10.10 1 205 1.6E-5 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_41610 17365c2fa0bec4ba7b4cb3df04e9f323 338 Pfam PF02720 Domain of unknown function (DUF222) 1 255 3.5E-12 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_05495 8b04ac3b286f47a51c641ef87bfd871e 127 Pfam PF14534 Domain of unknown function (DUF4440) 12 115 1.8E-13 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 A4R43_05495 8b04ac3b286f47a51c641ef87bfd871e 127 Gene3D G3DSA:3.10.450.50 9 126 9.4E-33 T 14-10-2018 A4R43_05495 8b04ac3b286f47a51c641ef87bfd871e 127 SUPERFAMILY SSF54427 9 123 2.06E-21 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_22025 ef6b7e38ea694f80292e6949415432ef 997 Pfam PF03699 Uncharacterised protein family (UPF0182) 20 825 1.6E-267 T 14-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 A4R43_22025 ef6b7e38ea694f80292e6949415432ef 997 Hamap MF_01600 UPF0182 protein . 11 901 17.932 T 14-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 A4R43_29675 a2c1d0962db5a6370a6789a4010e4faf 132 Pfam PF07811 TadE-like protein 7 47 4.5E-10 T 14-10-2018 IPR012495 TadE-like A4R43_16780 6cf4aa8af1c9c0f2a3782a0db422810c 241 Pfam PF04434 SWIM zinc finger 111 134 6.8E-5 T 14-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A4R43_32405 16e346398d3623bb9a2b41969888a7fa 205 Pfam PF12079 Protein of unknown function (DUF3558) 12 200 6.2E-29 T 14-10-2018 IPR024520 Protein of unknown function DUF3558 A4R43_12945 8dfdb2715ecef26aae5deb072d87ca7c 556 SUPERFAMILY SSF53756 114 333 2.41E-8 T 14-10-2018 A4R43_00175 6523817e94d1d0c839bdc2fc6d78b6b2 378 Pfam PF02720 Domain of unknown function (DUF222) 9 297 9.9E-12 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_18200 82a70ca68fdb5a5a53cc3c4cc7b5c36e 247 Pfam PF03883 Peroxide stress protein YaaA 2 213 2.2E-36 T 14-10-2018 IPR005583 Peroxide stress protein YaaA A4R43_33605 0a372c37b4818039f6ee82f4625d14ad 282 Pfam PF02405 Permease MlaE 65 267 2.1E-60 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_30110 bb1d0c8bc614a415a616f77769109441 765 SUPERFAMILY SSF82866 541 731 2.22E-13 T 14-10-2018 A4R43_30110 bb1d0c8bc614a415a616f77769109441 765 SUPERFAMILY SSF82866 193 394 2.88E-17 T 14-10-2018 A4R43_30110 bb1d0c8bc614a415a616f77769109441 765 Pfam PF03176 MMPL family 194 327 1.2E-5 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4R43_24510 274f415322fb6de967f7bcb97971023d 315 Pfam PF00146 NADH dehydrogenase 14 304 1.5E-40 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4R43_10855 aa53344226efe3b689f0a12817d04a1e 314 Pfam PF03547 Membrane transport protein 162 305 6.2E-18 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4R43_10855 aa53344226efe3b689f0a12817d04a1e 314 Pfam PF03547 Membrane transport protein 5 135 7.5E-9 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4R43_16640 58a9092c315943a60cc44375ec586575 261 Pfam PF02405 Permease MlaE 41 251 1.5E-66 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_22070 851577c8217e6eae280a466ede8420fc 297 Pfam PF08241 Methyltransferase domain 57 159 4.9E-16 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4R43_22070 851577c8217e6eae280a466ede8420fc 297 Gene3D G3DSA:3.40.50.150 3 270 4.8E-28 T 14-10-2018 A4R43_22070 851577c8217e6eae280a466ede8420fc 297 SUPERFAMILY SSF53335 25 204 1.17E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4R43_05850 62a304f0465cc62e4d4fbb7f54520a8c 68 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 7 64 4.1E-18 T 14-10-2018 IPR021074 Formate dehydrogenase, delta subunit A4R43_33390 661bdcf160a088f98453e7aed6901e86 292 Pfam PF00483 Nucleotidyl transferase 2 237 3.7E-62 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4R43_33390 661bdcf160a088f98453e7aed6901e86 292 SUPERFAMILY SSF53448 1 286 2.93E-85 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_33390 661bdcf160a088f98453e7aed6901e86 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 9.2E-138 T 14-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A4R43_33390 661bdcf160a088f98453e7aed6901e86 292 Gene3D G3DSA:3.90.550.10 1 291 1.1E-76 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4R43_27500 ba9b2c10616ec2eb4b6552e899825e88 83 Pfam PF04149 Domain of unknown function (DUF397) 23 76 2.9E-17 T 14-10-2018 IPR007278 Domain of unknown function DUF397 A4R43_31975 4faa4b7b4d63ea711bacdacd5c767291 211 Pfam PF14021 Tuberculosis necrotizing toxin 110 210 3.8E-32 T 14-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 A4R43_08345 2d291244a061b142dedf4aec7c8afd81 509 SUPERFAMILY SSF52402 52 219 1.4E-8 T 14-10-2018 A4R43_21485 3e9b8575d4b9af2c878f1491584886f6 150 Pfam PF03780 Asp23 family, cell envelope-related function 26 136 9.9E-31 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 A4R43_40780 42b43cbdbc1d3d1922c808bdc1b8ab0d 324 Pfam PF01040 UbiA prenyltransferase family 41 291 1.5E-20 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A4R43_20995 427d407c6cde7cc6bd3540e639094563 120 Pfam PF05331 Protein of unknown function (DUF742) 11 120 9.3E-34 T 14-10-2018 IPR007995 Protein of unknown function DUF742 A4R43_14520 da0a211e8d6f1adaada5664d10934739 322 Gene3D G3DSA:3.90.920.30 18 293 5.0E-77 T 14-10-2018 A4R43_37515 1f2f1ef33cfb4b246bce28ada27daa38 372 Pfam PF01882 Protein of unknown function DUF58 187 263 1.7E-23 T 14-10-2018 IPR002881 Domain of unknown function DUF58 A4R43_24130 4ae130b44f817150cf6d71c7a63aab59 191 Gene3D G3DSA:1.10.357.10 29 188 4.9E-12 T 14-10-2018 A4R43_24130 4ae130b44f817150cf6d71c7a63aab59 191 SUPERFAMILY SSF46689 20 73 7.56E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4R43_22880 c3daaa1b3fd2df26f70c9d82253a400b 221 Gene3D G3DSA:3.40.50.620 58 160 2.6E-11 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4R43_22880 c3daaa1b3fd2df26f70c9d82253a400b 221 Pfam PF02698 DUF218 domain 35 147 1.2E-16 T 14-10-2018 IPR003848 Domain of unknown function DUF218 A4R43_33430 2a5f50042af59b04e4fab2bc7a145205 325 Pfam PF03640 Secreted repeat of unknown function 64 102 9.2E-14 T 14-10-2018 IPR005297 Lipoprotein repeat A4R43_33430 2a5f50042af59b04e4fab2bc7a145205 325 Pfam PF03640 Secreted repeat of unknown function 122 162 3.8E-15 T 14-10-2018 IPR005297 Lipoprotein repeat A4R43_33430 2a5f50042af59b04e4fab2bc7a145205 325 Pfam PF03640 Secreted repeat of unknown function 248 289 4.6E-14 T 14-10-2018 IPR005297 Lipoprotein repeat A4R43_33430 2a5f50042af59b04e4fab2bc7a145205 325 Pfam PF03640 Secreted repeat of unknown function 192 229 1.8E-12 T 14-10-2018 IPR005297 Lipoprotein repeat A4R43_30795 db506e4d3a9b769a1298e80f6a62b10d 443 PIRSF PIRSF010361 3 437 9.9E-70 T 14-10-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane A4R43_30795 db506e4d3a9b769a1298e80f6a62b10d 443 Pfam PF09594 Glycosyltransferase family 87 92 335 6.1E-8 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_08970 6933410dc4e39839b7c25019e3e5ba81 506 Pfam PF09594 Glycosyltransferase family 87 193 418 6.0E-5 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_30250 83b185fd05a8bd3f19737c516a8e6bf3 347 Pfam PF13814 Replication-relaxation 46 229 3.1E-40 T 14-10-2018 IPR025855 Plasmid replication-relaxation A4R43_34240 e5848ebf51af87163c535d5badb7b2e3 414 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 149 4.6E-61 T 14-10-2018 IPR009827 Dicarboxylate carrier MatC N-terminal A4R43_36045 8dbbf52eb17d5aede9d4cf1ebcca063a 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 1.6E-11 T 14-10-2018 IPR003743 C4-type zinc ribbon domain A4R43_10745 852d79ae317bd38149a45c34fe895a42 327 Pfam PF13280 WYL domain 146 320 3.4E-27 T 14-10-2018 IPR026881 WYL domain A4R43_10220 c5e0d0d57918e7ebdc4ac0e288432f49 429 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 146 5.1E-33 T 14-10-2018 IPR009827 Dicarboxylate carrier MatC N-terminal A4R43_05360 aa304e77f7cc5fab4ba6147725d10f98 233 Pfam PF06197 Protein of unknown function (DUF998) 21 207 6.0E-23 T 14-10-2018 IPR009339 Protein of unknown function DUF998 A4R43_36130 9a48c2d5f1cbe0b5c28d4cd8eb319d98 242 Pfam PF03640 Secreted repeat of unknown function 129 168 3.3E-10 T 14-10-2018 IPR005297 Lipoprotein repeat A4R43_36130 9a48c2d5f1cbe0b5c28d4cd8eb319d98 242 Pfam PF03640 Secreted repeat of unknown function 185 227 4.8E-13 T 14-10-2018 IPR005297 Lipoprotein repeat A4R43_05130 c6923f40e4c577b5bd2463b1be1dc39f 422 Pfam PF09594 Glycosyltransferase family 87 155 389 8.1E-9 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A4R43_26790 74b5dbe1d50a5386b263b121c6b41808 153 Pfam PF11377 Protein of unknown function (DUF3180) 9 141 1.3E-40 T 14-10-2018 IPR021517 Protein of unknown function DUF3180 A4R43_21400 aee69aab63d5091935dc5bd248948904 317 SUPERFAMILY SSF50969 89 290 3.14E-9 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A4R43_30355 8643bf793064ac4a8bc4a63b73af4c1e 97 Gene3D G3DSA:3.40.50.1390 21 94 3.2E-8 T 14-10-2018 A4R43_21855 a8548be49275e56b9b8973ac1608b198 253 SUPERFAMILY SSF158791 76 165 1.24E-5 T 14-10-2018 A4R43_30675 589fec9841a7b744bb7645eb0a481d45 384 Pfam PF01594 AI-2E family transporter 23 345 1.5E-63 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like A4R43_20905 9f33805caad76ec05a3fe023c488b15b 275 Pfam PF01758 Sodium Bile acid symporter family 1 177 2.7E-33 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A4R43_20905 9f33805caad76ec05a3fe023c488b15b 275 Gene3D G3DSA:1.20.1530.20 1 268 4.5E-74 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily A4R43_18840 a1909a9e777e2ad09667a354d90b1355 262 Pfam PF02405 Permease MlaE 41 251 9.0E-66 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_22125 06a7c3872801ca172544b3665143aad0 251 Pfam PF00117 Glutamine amidotransferase class-I 45 186 5.5E-14 T 14-10-2018 IPR017926 Glutamine amidotransferase A4R43_22125 06a7c3872801ca172544b3665143aad0 251 Gene3D G3DSA:3.40.50.880 1 232 8.1E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_22125 06a7c3872801ca172544b3665143aad0 251 SUPERFAMILY SSF52317 19 192 9.48E-36 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like A4R43_28105 4ff122e1583ae269295f8219a9367916 260 Pfam PF14011 EspG family 8 252 1.4E-56 T 14-10-2018 IPR025734 EspG family A4R43_19985 2d80f406342290db009c21f96da42fd1 75 Pfam PF04149 Domain of unknown function (DUF397) 26 64 3.8E-4 T 14-10-2018 IPR007278 Domain of unknown function DUF397 A4R43_00260 f497c8e7749293df215959d803d7491e 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 327 5.7E-41 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_26545 bdf81bb1aa3c918420aa86bef4c1c999 359 SUPERFAMILY SSF110296 5 357 3.92E-64 T 14-10-2018 A4R43_26545 bdf81bb1aa3c918420aa86bef4c1c999 359 Gene3D G3DSA:2.130.10.10 1 358 1.4E-124 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4R43_34995 90e6354757858e4db1a5c09a3ae2ba02 140 Pfam PF13772 AIG2-like family 49 130 1.8E-21 T 14-10-2018 A4R43_34995 90e6354757858e4db1a5c09a3ae2ba02 140 Gene3D G3DSA:3.10.490.10 1 138 4.6E-36 T 14-10-2018 A4R43_34995 90e6354757858e4db1a5c09a3ae2ba02 140 SUPERFAMILY SSF110857 2 109 7.19E-13 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily A4R43_32410 429a5ac05dc7fb010dd2af42379ac923 409 SUPERFAMILY SSF140459 15 160 4.45E-5 T 14-10-2018 A4R43_28405 89a0e0a141b3228d48981a0225d964f5 443 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 37 434 5.5E-115 T 14-10-2018 IPR018721 Protein of unknown function DUF2252 A4R43_16970 fcc10c8d80d62e1460b25c68490e9279 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 9.2E-27 T 14-10-2018 IPR021408 Protein of unknown function DUF3046 A4R43_41365 5a53c19448c8714ab9a665855503185b 134 Pfam PF11239 Protein of unknown function (DUF3040) 1 85 3.4E-30 T 14-10-2018 IPR021401 Protein of unknown function DUF3040 A4R43_04300 0dbe07b3fa19fa8938e872e27122dd76 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 9 102 2.0E-12 T 14-10-2018 IPR008407 Branched-chain amino acid transport, AzlD A4R43_13235 a7d32d9cbc9bdd2fb2c87e2896559eab 369 Pfam PF02720 Domain of unknown function (DUF222) 12 286 1.1E-11 T 14-10-2018 IPR003870 Domain of unknown function DUF222 A4R43_18525 e667d94e4fcf1b43c916af4d4e0dee41 206 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 172 192 6.3E-8 T 14-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 A4R43_31380 99bc25f0c8ab248e19e139c2adce4d9a 257 Pfam PF13349 Putative adhesin 103 255 1.1E-12 T 14-10-2018 IPR025164 Putative adhesin A4R43_24650 a15981ebd2c3c9ef570d8ede485a7f49 277 Pfam PF07485 Domain of Unknown Function (DUF1259) 152 269 1.9E-45 T 14-10-2018 IPR011094 Uncharacterised protein family, LppY/LpqO A4R43_24650 a15981ebd2c3c9ef570d8ede485a7f49 277 Pfam PF07485 Domain of Unknown Function (DUF1259) 10 130 1.7E-38 T 14-10-2018 IPR011094 Uncharacterised protein family, LppY/LpqO A4R43_08020 148aff410bdcead2c39fab55e33b7179 459 SUPERFAMILY SSF53474 61 432 4.78E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold A4R43_08020 148aff410bdcead2c39fab55e33b7179 459 Pfam PF00561 alpha/beta hydrolase fold 68 431 9.9E-25 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4R43_16600 efd3b6935d94870f0c581425cdb10bb4 158 SUPERFAMILY SSF54427 64 157 2.22E-5 T 14-10-2018 IPR032710 NTF2-like domain superfamily A4R43_38615 4d13af18838c68d4b6718b133868393d 214 Pfam PF01184 GPR1/FUN34/yaaH family 30 202 7.1E-25 T 14-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 A4R43_22340 a9c3a11321ada80592069e3935616d91 143 Pfam PF10739 Protein of unknown function (DUF2550) 12 137 2.5E-44 T 14-10-2018 IPR019675 Protein of unknown function DUF2550 A4R43_13835 7d86f6041a00a7c9a1659f886a29ee08 187 Pfam PF11452 Protein of unknown function (DUF3000) 8 178 1.1E-69 T 14-10-2018 IPR021555 Protein of unknown function DUF3000 A4R43_28315 57f87536c16b78fe0e94c209ac4952cc 209 Pfam PF14273 Domain of unknown function (DUF4360) 30 209 1.2E-68 T 14-10-2018 IPR025649 Protein of unknown function DUF4360 A4R43_31080 b5b97028c1b4f99845a029e7b650e947 178 Pfam PF07681 DoxX 6 99 1.2E-10 T 14-10-2018 IPR032808 DoxX family A4R43_03510 51df8ef7ed0cd1343c8480f59b8eabc6 392 Pfam PF05816 Toxic anion resistance protein (TelA) 54 376 9.1E-72 T 14-10-2018 IPR008863 Toxic anion resistance A4R43_36825 70500fd478c2a9c52161ea104dba27c8 711 Gene3D G3DSA:2.60.60.30 477 637 2.0E-5 T 14-10-2018 A4R43_06990 d7603cf6b55767b18fe36cd04ff1fd5d 514 Pfam PF03806 AbgT putative transporter family 19 513 1.1E-165 T 14-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 A4R43_09100 e20a46d2740b218303dafa1f6dbf36da 594 Pfam PF17128 Domain of unknown function (DUF5107) 54 340 4.5E-32 T 14-10-2018 IPR033396 Domain of unknown function DUF5107 A4R43_17045 3f57852e12292292c0c0a251a7ef7554 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 4 99 4.2E-9 T 14-10-2018 IPR008407 Branched-chain amino acid transport, AzlD A4R43_34760 bbfac85fbd18404dd240fa5d26983233 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 327 8.6E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_34555 540f73bdaa7ae96a021cb228960e9f64 101 Pfam PF11222 Protein of unknown function (DUF3017) 22 94 2.7E-21 T 14-10-2018 IPR021385 Protein of unknown function DUF3017 A4R43_15820 9c6dd4472d1f580b4ed1cccffb1a9dac 112 Pfam PF11298 Protein of unknown function (DUF3099) 20 88 8.2E-31 T 14-10-2018 IPR021449 Protein of unknown function DUF3099 A4R43_27485 0b61a157ffff5ced136a1a9bc062e5c2 136 Pfam PF13115 YtkA-like 39 116 1.5E-9 T 14-10-2018 IPR032693 YtkA-like domain A4R43_15560 5ed9c4ca8bc4d833df477408c3272df6 343 Pfam PF06081 Aromatic acid exporter family member 1 12 147 2.1E-11 T 14-10-2018 IPR010343 Aromatic acid exporter family member 1 A4R43_33600 212a4c42abe3e470d5352d4c704f0657 263 Pfam PF02405 Permease MlaE 42 253 6.6E-65 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4R43_28630 8b5e4edb2fd16fba898d8b40169d79cf 113 Pfam PF04341 Protein of unknown function, DUF485 16 102 8.1E-37 T 14-10-2018 IPR007436 Protein of unknown function DUF485 A4R43_12350 ac47721a061ab9071e6239c768e99997 62 Pfam PF12728 Helix-turn-helix domain 5 50 1.4E-7 T 14-10-2018 A4R43_26065 5f305660c16d0e3db97b51ab923a0231 275 Pfam PF13359 DDE superfamily endonuclease 127 267 2.3E-21 T 14-10-2018 IPR027806 Harbinger transposase-derived nuclease domain A4R43_26480 46d939572bdd5a3742397570604b8ae7 265 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 15 234 2.4E-31 T 14-10-2018 A4R43_03080 23fb9d0564cfbf87bb5eae4689890213 185 Pfam PF14016 Protein of unknown function (DUF4232) 43 181 2.2E-25 T 14-10-2018 IPR025326 Protein of unknown function DUF4232 A4R43_41830 29b366661759bcf1e43636dc4190ee00 608 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 82 236 1.2E-31 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4R43_27370 bad01ac8469d04018cc0efe77d292b8a 184 Pfam PF09335 SNARE associated Golgi protein 17 142 1.7E-14 T 14-10-2018 IPR032816 SNARE associated Golgi protein A4R43_03340 5892492521da79746ee6b07c2b242fe3 257 Pfam PF01925 Sulfite exporter TauE/SafE 5 250 6.1E-25 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A4R43_15800 2a832d3c63d864858bcbb0f804ec79d1 269 Pfam PF07070 SpoOM protein 2 218 5.7E-60 T 14-10-2018 IPR009776 Sporulation stage 0, protein M A4R43_10460 6a343e0e8b95c3977a2e1b18eaffc765 152 Pfam PF06803 Protein of unknown function (DUF1232) 95 130 2.7E-13 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 A4R43_35775 3aad5425f5031204f4ac924ed39e82cd 365 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 10 364 8.1E-108 T 14-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 A4R43_23400 a31cd5092a7fbd325e59a144c011b238 285 Pfam PF12679 ABC-2 family transporter protein 16 224 2.2E-13 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A4R43_30635 0df9cbae7e1a58faa9b0e4abcd4951e2 609 Pfam PF10101 Predicted membrane protein (DUF2339) 103 499 7.7E-18 T 14-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane A4R43_30635 0df9cbae7e1a58faa9b0e4abcd4951e2 609 Pfam PF10101 Predicted membrane protein (DUF2339) 409 596 9.4E-11 T 14-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane A4R43_17750 3b3784aa0f2bd72b02904caa29b98be3 226 Pfam PF05893 Acyl-CoA reductase (LuxC) 110 208 1.2E-11 T 14-10-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 A4R43_35230 a05b3dcf71fb06ef1dd27d1aa3accf32 156 Pfam PF02575 YbaB/EbfC DNA-binding family 21 98 2.2E-9 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4R43_35230 a05b3dcf71fb06ef1dd27d1aa3accf32 156 Gene3D G3DSA:3.30.1310.10 8 104 8.7E-6 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_35230 a05b3dcf71fb06ef1dd27d1aa3accf32 156 SUPERFAMILY SSF82607 24 97 2.35E-6 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4R43_12635 a63bfea4d3b955fa325c9f8c3a33c586 169 Pfam PF13276 HTH-like domain 102 153 7.2E-16 T 14-10-2018 IPR025948 HTH-like domain A4R43_38050 764ea8ca2e414aaeca576121c9b4e85c 62 Pfam PF17227 Family of unknown function (DUF5302) 12 62 7.3E-24 T 14-10-2018 IPR035172 Protein of unknown function DUF5302 A4R43_02335 2f77184aaab436e8d67bb8ed4908ba5f 606 Gene3D G3DSA:3.50.30.30 358 465 1.1E-7 T 14-10-2018 A4R43_01285 32597dc46819d2e3c10e71537a12cd2e 113 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 40 78 1.5E-7 T 14-10-2018 IPR026496 Putative ATP-grasp target RiPP A4R43_04210 cea0c822d14064988fcf9afb3a5a88f9 237 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 81 231 1.1E-17 T 14-10-2018 IPR023840 Type VII secretion system Rv3446c A4R43_28700 84b44ca6fcf9e060595bf5a15a505212 97 Pfam PF05360 yiaA/B two helix domain 15 67 3.7E-18 T 14-10-2018 IPR008024 YiaAB two helix A4R43_36085 40ce06d888c47ee3755350c6066d303f 299 Pfam PF02104 SURF1 family 21 227 1.0E-24 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4R43_38175 c399947702b856246662de8a877994d7 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 325 1.5E-41 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4R43_01900 f2c401f3b9b93845920c9bb2a1ce2e55 452 Pfam PF02386 Cation transport protein 43 431 2.8E-54 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A4R43_27530 f7de1ab9e8f3b810c79df2dd4156b6cb 277 Pfam PF02517 CAAX protease self-immunity 133 221 4.0E-12 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A4R43_28615 824b0918b5733a5cdce655c17f378a6b 292 Pfam PF14219 Domain of unknown function (DUF4328) 97 255 8.2E-36 T 14-10-2018 IPR025565 Domain of unknown function DUF4328 A4R43_33320 20906cfc5649000394fa0655fab67ff4 473 Pfam PF13440 Polysaccharide biosynthesis protein 35 325 6.1E-61 T 14-10-2018 A4R43_28730 b410e47a2339bb7d00e68a9fc9ebaabf 377 Pfam PF01757 Acyltransferase family 22 338 1.6E-25 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A4R43_22470 08e8b7f07d6121d3b1471f8576eab4d3 230 Pfam PF11303 Protein of unknown function (DUF3105) 76 202 5.1E-43 T 14-10-2018 IPR021454 Protein of unknown function DUF3105 A4R43_28295 e0ef41f60f85b2b416f576cbfa96f04c 216 Gene3D G3DSA:2.160.10.10 3 173 2.3E-38 T 14-10-2018 A4R43_28295 e0ef41f60f85b2b416f576cbfa96f04c 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 113 146 1.5E-8 T 14-10-2018 IPR001451 Hexapeptide repeat A4R43_28295 e0ef41f60f85b2b416f576cbfa96f04c 216 SUPERFAMILY SSF51161 42 174 8.46E-37 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily A4R43_04650 a7afe3f50a95fd86a8cc85fcbd02b5d9 204 Pfam PF01478 Type IV leader peptidase family 65 171 9.9E-13 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A4R43_40045 fafbd3d25dbf0b660434c6623297669d 286 SUPERFAMILY SSF89372 34 212 6.41E-7 T 14-10-2018 A4R43_15570 71618dd4ef56d5d6133ffaea13dc1df5 87 Pfam PF04972 BON domain 13 75 4.0E-7 T 14-10-2018 IPR007055 BON domain A4R43_35835 4931a0ff5cd1579c408569cb79d9e30b 76 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 2.8E-28 T 14-10-2018 IPR021456 Protein of unknown function DUF3107 A4R43_18120 406b2c97866e6e16832bf2abc41b02ac 101 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 6 89 2.1E-31 T 14-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 A4R43_16490 0dae7525e24039b0d6c984083f00600b 94 Pfam PF02325 YGGT family 9 90 3.4E-13 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020