locus-tag	class	description
RAM_00010	COG0592	DNA-directed DNA polymerase activity
RAM_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
RAM_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RAM_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
RAM_00030	COG0187	DNA topoisomerase II activity
RAM_00145	COG0596	Alpha beta hydrolase
RAM_00180	COG0705	Rhomboid family
RAM_00180	COG0457	Tetratricopeptide repeat
RAM_00195	COG3764	Sortase (surface protein transpeptidase)
RAM_00255	COG0515	serine threonine protein kinase
RAM_00255	COG2815	serine threonine protein kinase
RAM_00260	COG0515	serine threonine protein kinase
RAM_00265	COG0768	penicillin binding
RAM_00280	COG1716	ATPase activity
RAM_00285	COG1716	ATPase activity
RAM_00310	COG0626	cystathionine gamma-synthase activity
RAM_00330	COG2186	Transcriptional regulator
RAM_00335	COG0747	negative chemotaxis
RAM_00350	COG0444	Belongs to the ABC transporter superfamily
RAM_00355	COG4608	Belongs to the ABC transporter superfamily
RAM_00360	COG1012	belongs to the aldehyde dehydrogenase family
RAM_00365	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_00370	COG0154	amidase activity
RAM_00395	COG2301	Belongs to the HpcH HpaI aldolase family
RAM_00405	COG0702	epimerase
RAM_00410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RAM_00425	COG1309	transcriptional regulator
RAM_00435	COG2211	Major facilitator Superfamily
RAM_00470	COG1276	copper resistance
RAM_00470	COG2372	response to copper ion
RAM_00485	COG1174	glycine betaine transport
RAM_00495	COG1174	glycine betaine transport
RAM_00520	COG2226	methyltransferase
RAM_00530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RAM_00535	COG0405	Gamma-glutamyltransferase
RAM_00545	COG5433	transposase activity
RAM_00560	COG0477	Major facilitator Superfamily
RAM_00570	COG4585	Histidine kinase
RAM_00575	COG2197	response regulator
RAM_00610	COG0438	transferase activity, transferring glycosyl groups
RAM_00660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RAM_00665	COG3275	phosphorelay sensor kinase activity
RAM_00690	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_00695	COG0425	Belongs to the sulfur carrier protein TusA family
RAM_00695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RAM_00720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_00740	COG1191	sigma factor activity
RAM_00755	COG2235	arginine
RAM_00825	COG1271	oxidase subunit
RAM_00830	COG1294	oxidase, subunit
RAM_00835	COG4988	ABC transporter
RAM_00890	COG4715	Zinc finger, swim domain protein
RAM_00910	COG1072	(Pantothenic acid kinase))
RAM_00915	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RAM_00925	COG0406	alpha-ribazole phosphatase activity
RAM_00960	COG0754	glutathionylspermidine amidase activity
RAM_00970	COG0596	Alpha beta hydrolase
RAM_00975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RAM_00980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RAM_00990	COG0579	oxidoreductase
RAM_01015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RAM_01030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RAM_01060	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RAM_01070	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_01075	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_01120	COG0561	phosphatase activity
RAM_01125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_01145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RAM_01160	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_01165	COG0277	FAD linked oxidase domain protein
RAM_01175	COG1216	Glycosyl transferase, family 2
RAM_01205	COG1216	Glycosyl transferase, family 2
RAM_01230	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_01230	COG0604	alcohol dehydrogenase
RAM_01230	COG3321	synthase
RAM_01235	COG2234	aminopeptidase activity
RAM_01290	COG4565	transcriptional regulatory protein
RAM_01295	COG3290	protein histidine kinase activity
RAM_01300	COG1116	anion transmembrane transporter activity
RAM_01325	COG1672	PFAM Archaeal ATPase
RAM_01325	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RAM_01340	COG1522	sequence-specific DNA binding
RAM_01345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_01355	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_01360	COG2186	Transcriptional regulator
RAM_01375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RAM_01385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_01405	COG3469	chitinase activity
RAM_01410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RAM_01435	COG3584	3D domain protein
RAM_01435	COG3583	domain protein
RAM_01510	COG3559	Exporter of polyketide antibiotics
RAM_01515	COG1131	(ABC) transporter
RAM_01570	COG0287	Prephenate dehydrogenase
RAM_01575	COG1902	pentaerythritol trinitrate reductase activity
RAM_01575	COG0446	pyridine nucleotide-disulphide oxidoreductase
RAM_01595	COG1846	Transcriptional regulator
RAM_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RAM_01635	COG2318	DinB family
RAM_01710	COG0515	serine threonine protein kinase
RAM_01730	COG0028	Belongs to the TPP enzyme family
RAM_01750	COG3199	ATP-NAD kinase
RAM_01755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RAM_01770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_01775	COG0515	serine threonine protein kinase
RAM_01910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_01945	COG2226	methyltransferase
RAM_01985	COG2233	PERMEase
RAM_01990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RAM_02000	COG1414	Transcriptional regulator
RAM_02020	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RAM_02115	COG2515	1-aminocyclopropane-1-carboxylate deaminase
RAM_02140	COG2364	Membrane
RAM_02145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_02160	COG2733	membrane
RAM_02180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RAM_02215	COG2986	histidine ammonia-lyase
RAM_02245	COG1174	glycine betaine transport
RAM_02260	COG1846	Transcriptional regulator
RAM_02270	COG2130	NADP-dependent
RAM_02285	COG1064	alcohol dehydrogenase
RAM_02315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RAM_02330	COG0438	transferase activity, transferring glycosyl groups
RAM_02345	COG0588	phosphoglycerate mutase activity
RAM_02355	COG0667	Aldo Keto reductase
RAM_02360	COG5002	protein histidine kinase activity
RAM_02390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RAM_02415	COG4585	Histidine kinase
RAM_02430	COG0560	Phosphoserine phosphatase
RAM_02440	COG1595	DNA-templated transcription, initiation
RAM_02445	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_02460	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
RAM_02465	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RAM_02470	COG0181	hydroxymethylbilane synthase activity
RAM_02475	COG1648	precorrin-2 dehydrogenase activity
RAM_02475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RAM_02510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RAM_02515	COG0577	efflux transmembrane transporter activity
RAM_02515	COG1136	(ABC) transporter
RAM_02520	COG1136	(ABC) transporter
RAM_02520	COG0577	efflux transmembrane transporter activity
RAM_02535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RAM_02540	COG0406	alpha-ribazole phosphatase activity
RAM_02545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RAM_02550	COG0785	Cytochrome C biogenesis protein
RAM_02560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RAM_02580	COG1522	sequence-specific DNA binding
RAM_02615	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RAM_02640	COG0438	transferase activity, transferring glycosyl groups
RAM_02655	COG2226	methyltransferase
RAM_02660	COG0644	oxidoreductase
RAM_02670	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RAM_02675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RAM_02680	COG0649	NAD binding
RAM_02695	COG1034	ATP synthesis coupled electron transport
RAM_02700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RAM_02705	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RAM_02710	COG0839	Belongs to the complex I subunit 6 family
RAM_02715	COG0713	ATP synthesis coupled electron transport
RAM_02720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RAM_02730	COG1007	ATP synthesis coupled electron transport
RAM_02770	COG1013	pyruvate-flavodoxin oxidoreductase activity
RAM_02775	COG0674	pyruvate-flavodoxin oxidoreductase activity
RAM_02775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RAM_02785	COG1522	sequence-specific DNA binding
RAM_02790	COG1834	amidinotransferase
RAM_02805	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RAM_02810	COG0438	transferase activity, transferring glycosyl groups
RAM_02825	COG0367	asparagine synthase
RAM_02870	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RAM_02875	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RAM_02885	COG1215	transferase activity, transferring glycosyl groups
RAM_02895	COG4310	Domain of unknown function (DUF2172)
RAM_02910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RAM_02925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_02965	COG1666	GTP binding
RAM_02980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RAM_03000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RAM_03005	COG2030	dehydratase
RAM_03025	COG1725	Transcriptional regulator
RAM_03045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RAM_03050	COG0081	regulation of translation
RAM_03065	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RAM_03085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_03110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RAM_03135	COG0673	inositol 2-dehydrogenase activity
RAM_03195	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RAM_03200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RAM_03215	COG0546	phosphoglycolate phosphatase activity
RAM_03225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_03235	COG0477	Major facilitator Superfamily
RAM_03250	COG2124	cytochrome p450
RAM_03255	COG2124	cytochrome p450
RAM_03275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_03290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_03315	COG2124	cytochrome p450
RAM_03325	COG3959	Transketolase, thiamine diphosphate binding domain
RAM_03330	COG3958	Transketolase
RAM_03340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RAM_03355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RAM_03365	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RAM_03370	COG1522	sequence-specific DNA binding
RAM_03375	COG0477	Major facilitator Superfamily
RAM_03385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_03385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_03435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RAM_03440	COG0049	tRNA binding
RAM_03445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RAM_03455	COG0051	transcription antitermination factor activity, RNA binding
RAM_03460	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RAM_03465	COG0088	Forms part of the polypeptide exit tunnel
RAM_03470	COG0089	rRNA binding
RAM_03475	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RAM_03480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RAM_03485	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RAM_03490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RAM_03495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RAM_03500	COG0255	Belongs to the universal ribosomal protein uL29 family
RAM_03505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RAM_03510	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RAM_03515	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RAM_03520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RAM_03530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RAM_03535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RAM_03540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RAM_03545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RAM_03550	COG1841	ribosomal large subunit assembly
RAM_03555	COG0200	Binds to the 23S rRNA
RAM_03565	COG1280	lysine exporter protein (LysE YggA)
RAM_03575	COG0563	adenylate kinase activity
RAM_03590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RAM_03595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RAM_03605	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RAM_03610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RAM_03615	COG0202	RNA polymerase activity
RAM_03620	COG0203	ribosomal protein L17
RAM_03625	COG0101	tRNA pseudouridine synthase activity
RAM_03660	COG1404	Belongs to the peptidase S8 family
RAM_03670	COG1674	ftsk spoiiie
RAM_03675	COG0443	Heat shock 70 kDa protein
RAM_03705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RAM_03710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RAM_03715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RAM_03765	COG1349	DNA-binding transcription factor activity
RAM_03770	COG1070	Carbohydrate kinase
RAM_03775	COG3842	ATPase activity
RAM_03780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RAM_03790	COG0802	atpase or kinase
RAM_03800	COG0825	malonyl-CoA metabolic process
RAM_03800	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RAM_03805	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_03815	COG0456	acetyltransferase
RAM_03820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RAM_03825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RAM_03845	COG1215	transferase activity, transferring glycosyl groups
RAM_03855	COG2226	methyltransferase
RAM_03870	COG0798	PFAM Bile acid sodium symporter
RAM_03875	COG0640	Transcriptional regulator
RAM_03885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RAM_03890	COG0459	protein refolding
RAM_03950	COG0516	GMP reductase activity
RAM_03970	COG0277	FAD linked oxidase domain protein
RAM_03975	COG1012	belongs to the aldehyde dehydrogenase family
RAM_03995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RAM_03995	COG0519	Catalyzes the synthesis of GMP from XMP
RAM_04010	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_04030	COG0697	spore germination
RAM_04035	COG0583	DNA-binding transcription factor activity
RAM_04045	COG2815	serine threonine protein kinase
RAM_04045	COG0515	serine threonine protein kinase
RAM_04100	COG0045	succinate-CoA ligase (ADP-forming) activity
RAM_04125	COG0138	bifunctional purine biosynthesis protein purh
RAM_04165	COG0587	DNA-directed DNA polymerase activity
RAM_04185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RAM_04195	COG2814	Major facilitator Superfamily
RAM_04200	COG0640	Transcriptional regulator
RAM_04205	COG2814	Major facilitator Superfamily
RAM_04215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RAM_04240	COG2226	methyltransferase
RAM_04275	COG1234	tRNA 3'-trailer cleavage
RAM_04290	COG0180	Tryptophanyl-tRNA synthetase
RAM_04300	COG1295	ribonuclease BN
RAM_04310	COG1733	regulation of RNA biosynthetic process
RAM_04335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RAM_04350	COG2009	succinate dehydrogenase
RAM_04355	COG3345	alpha-galactosidase
RAM_04360	COG1082	Xylose isomerase domain protein TIM barrel
RAM_04400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RAM_04405	COG2271	Major facilitator Superfamily
RAM_04430	COG1733	regulation of RNA biosynthetic process
RAM_04440	COG1063	alcohol dehydrogenase
RAM_04455	COG0395	ABC-type sugar transport system, permease component
RAM_04490	COG1012	belongs to the aldehyde dehydrogenase family
RAM_04495	COG1012	belongs to the aldehyde dehydrogenase family
RAM_04500	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RAM_04540	COG0789	Transcriptional regulator
RAM_04545	COG0667	Aldo Keto reductase
RAM_04565	COG0475	glutathione-regulated potassium exporter activity
RAM_04570	COG0745	RESPONSE REGULATOR receiver
RAM_04575	COG2205	protein histidine kinase activity
RAM_04595	COG0402	S-adenosylhomocysteine deaminase activity
RAM_04620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RAM_04650	COG0515	serine threonine protein kinase
RAM_04675	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_04675	COG1473	amidohydrolase
RAM_04715	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RAM_04720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RAM_04725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RAM_04760	COG4770	biotin carboxylase activity
RAM_04775	COG1301	dicarboxylic acid transport
RAM_04780	COG0424	maF-like protein
RAM_04785	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_04805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_04810	COG1846	Transcriptional regulator
RAM_04820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_04835	COG4585	Histidine kinase
RAM_04855	COG1309	transcriptional regulator
RAM_04865	COG1733	regulation of RNA biosynthetic process
RAM_04875	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_04890	COG0583	DNA-binding transcription factor activity
RAM_04905	COG2226	methyltransferase
RAM_04920	COG0446	pyridine nucleotide-disulphide oxidoreductase
RAM_04920	COG1902	pentaerythritol trinitrate reductase activity
RAM_04940	COG4585	Histidine kinase
RAM_04945	COG2197	response regulator
RAM_04950	COG1388	LysM domain
RAM_04950	COG0791	NLP P60 protein
RAM_04950	COG3103	Sh3 type 3 domain protein
RAM_04965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RAM_04980	COG3537	Alpha-1,2-mannosidase
RAM_04985	COG0483	inositol monophosphate 1-phosphatase activity
RAM_04995	COG2205	protein histidine kinase activity
RAM_05000	COG2197	response regulator
RAM_05005	COG2197	response regulator
RAM_05070	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_05085	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RAM_05115	COG1316	TRANSCRIPTIONal
RAM_05120	COG1316	TRANSCRIPTIONal
RAM_05150	COG0438	transferase activity, transferring glycosyl groups
RAM_05185	COG1725	Transcriptional regulator
RAM_05200	COG0778	Nitroreductase
RAM_05200	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
RAM_05295	COG1611	Belongs to the LOG family
RAM_05315	COG1216	Glycosyl transferase, family 2
RAM_05340	COG0463	Glycosyl transferase, family 2
RAM_05345	COG1132	(ABC) transporter
RAM_05350	COG4988	ABC transporter
RAM_05355	COG1294	oxidase, subunit
RAM_05360	COG1271	oxidase subunit
RAM_05385	COG2818	Glycosylase
RAM_05390	COG1024	Enoyl-CoA hydratase
RAM_05400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RAM_05405	COG0583	DNA-binding transcription factor activity
RAM_05410	COG2814	Major facilitator Superfamily
RAM_05420	COG4122	O-methyltransferase activity
RAM_05425	COG1595	DNA-templated transcription, initiation
RAM_05435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_05440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RAM_05455	COG2239	Acts as a magnesium transporter
RAM_05465	COG0330	HflC and HflK could
RAM_05520	COG1309	transcriptional regulator
RAM_05530	COG2197	response regulator
RAM_05535	COG4585	Histidine kinase
RAM_05570	COG0598	Magnesium transport protein CorA
RAM_05600	COG0613	PHP domain protein
RAM_05605	COG2095	MarC family integral membrane protein
RAM_05630	COG0513	Belongs to the DEAD box helicase family
RAM_05665	COG2267	carboxylic ester hydrolase activity
RAM_05670	COG1309	transcriptional regulator
RAM_05675	COG2267	carboxylic ester hydrolase activity
RAM_05695	COG0243	molybdopterin cofactor binding
RAM_05700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RAM_05710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RAM_05710	COG2146	nitrite reductase [NAD(P)H] activity
RAM_05715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RAM_05715	COG2146	nitrite reductase [NAD(P)H] activity
RAM_05740	COG2378	regulation of single-species biofilm formation
RAM_05800	COG0714	Associated with various cellular activities
RAM_05825	COG2321	neutral zinc metallopeptidase
RAM_05845	COG0612	Peptidase, M16
RAM_05865	COG1175	transmembrane transport
RAM_05870	COG0395	ABC-type sugar transport system, permease component
RAM_05875	COG1486	melibiose metabolic process
RAM_05890	COG0640	Transcriptional regulator
RAM_05905	COG3265	gluconokinase activity
RAM_05915	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RAM_05950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RAM_05960	COG0328	RNA-DNA hybrid ribonuclease activity
RAM_05960	COG0406	alpha-ribazole phosphatase activity
RAM_05970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RAM_06065	COG1012	belongs to the aldehyde dehydrogenase family
RAM_06095	COG1012	belongs to the aldehyde dehydrogenase family
RAM_06100	COG3842	ATPase activity
RAM_06105	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RAM_06110	COG1176	ABC-type spermidine putrescine transport system, permease component I
RAM_06115	COG1177	transmembrane transport
RAM_06120	COG0596	Alpha beta hydrolase
RAM_06125	COG1968	undecaprenyl-diphosphatase activity
RAM_06135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RAM_06140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RAM_06140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RAM_06150	COG2318	DinB family
RAM_06165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RAM_06165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RAM_06170	COG0653	protein targeting
RAM_06190	COG0174	glutamine synthetase
RAM_06195	COG0154	amidase activity
RAM_06200	COG1522	sequence-specific DNA binding
RAM_06210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RAM_06210	COG0519	Catalyzes the synthesis of GMP from XMP
RAM_06225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RAM_06235	COG0174	glutamine synthetase
RAM_06295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RAM_06315	COG3480	Lon protease (S16) C-terminal proteolytic domain
RAM_06325	COG1615	UPF0182 protein
RAM_06345	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RAM_06350	COG2884	Cell division ATP-binding protein ftsE
RAM_06355	COG2177	Part of the ABC transporter FtsEX involved in
RAM_06360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RAM_06385	COG2197	response regulator
RAM_06390	COG4585	Histidine kinase
RAM_06405	COG3706	GGDEF domain
RAM_06420	COG2986	histidine ammonia-lyase
RAM_06425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RAM_06435	COG0402	S-adenosylhomocysteine deaminase activity
RAM_06440	COG1228	amidohydrolase
RAM_06445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_06480	COG4585	Histidine kinase
RAM_06510	COG1131	(ABC) transporter
RAM_06515	COG1643	Atp-dependent helicase
RAM_06520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_06540	COG0791	NLP P60 protein
RAM_06540	COG3883	PFAM NLP P60 protein
RAM_06555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_06565	COG2318	DinB family
RAM_06570	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_06580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RAM_06585	COG0187	DNA topoisomerase II activity
RAM_06630	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_06635	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_06640	COG1129	ABC transporter
RAM_06645	COG1879	ABC-type sugar transport system periplasmic component
RAM_06650	COG1609	Transcriptional regulator
RAM_06655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RAM_06665	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_06685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RAM_06715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_06745	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_06755	COG0017	Asparaginyl-tRNA synthetase
RAM_06775	COG0596	Alpha beta hydrolase
RAM_06800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_06805	COG1486	melibiose metabolic process
RAM_06815	COG1053	succinate dehydrogenase
RAM_06820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_06825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RAM_06835	COG0596	Alpha beta hydrolase
RAM_06925	COG0697	spore germination
RAM_06930	COG1846	Transcriptional regulator
RAM_06965	COG3629	intracellular signal transduction
RAM_06965	COG3903	Transcriptional regulator
RAM_06975	COG2211	Major facilitator Superfamily
RAM_06980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RAM_06985	COG0411	ABC transporter
RAM_06990	COG0410	ABC transporter
RAM_07010	COG1309	transcriptional regulator
RAM_07040	COG1136	(ABC) transporter
RAM_07095	COG0477	Major facilitator Superfamily
RAM_07110	COG3387	PFAM Glycoside hydrolase 15-related
RAM_07115	COG1063	alcohol dehydrogenase
RAM_07135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_07190	COG3209	COG3209 Rhs family protein
RAM_07225	COG0604	alcohol dehydrogenase
RAM_07225	COG3321	synthase
RAM_07225	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_07255	COG2018	Roadblock/LC7 domain
RAM_07280	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_07285	COG0583	DNA-binding transcription factor activity
RAM_07290	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_07300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_07335	COG0667	Aldo Keto reductase
RAM_07345	COG1595	DNA-templated transcription, initiation
RAM_07380	COG3903	Transcriptional regulator
RAM_07380	COG3629	intracellular signal transduction
RAM_07390	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
RAM_07420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RAM_07425	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_07465	COG1234	tRNA 3'-trailer cleavage
RAM_07475	COG3852	Histidine kinase
RAM_07480	COG2272	Belongs to the type-B carboxylesterase lipase family
RAM_07535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RAM_07615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_07620	COG0765	amino acid transport
RAM_07625	COG1126	abc transporter atp-binding protein
RAM_07630	COG2964	Protein conserved in bacteria
RAM_07645	COG0596	Alpha beta hydrolase
RAM_07650	COG1131	(ABC) transporter
RAM_07680	COG2186	Transcriptional regulator
RAM_07685	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_07690	COG1129	ABC transporter
RAM_07710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_07710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_07715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_07730	COG1879	ABC-type sugar transport system periplasmic component
RAM_07765	COG3540	Alkaline phosphatase
RAM_07775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RAM_07785	COG3408	Glycogen debranching enzyme
RAM_07785	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
RAM_07790	COG1940	carbohydrate kinase activity
RAM_07810	COG4221	oxidoreductase activity
RAM_07815	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RAM_07835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_07850	COG0513	Belongs to the DEAD box helicase family
RAM_07875	COG2183	response to ionizing radiation
RAM_07890	COG2072	flavoprotein involved in K transport
RAM_07895	COG2072	flavoprotein involved in K transport
RAM_07940	COG1012	belongs to the aldehyde dehydrogenase family
RAM_07940	COG2030	dehydratase
RAM_07945	COG3396	Phenylacetate-CoA oxygenase
RAM_07950	COG3460	Phenylacetate-CoA oxygenase
RAM_07955	COG3396	Phenylacetate-CoA oxygenase
RAM_07960	COG2151	metal-sulfur cluster biosynthetic enzyme
RAM_07965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RAM_07980	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RAM_08015	COG0183	Belongs to the thiolase family
RAM_08030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_08035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RAM_08040	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RAM_08045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_08055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_08065	COG3279	Response regulator of the LytR AlgR family
RAM_08070	COG3275	phosphorelay sensor kinase activity
RAM_08080	COG1879	ABC-type sugar transport system periplasmic component
RAM_08085	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_08100	COG1609	Transcriptional regulator
RAM_08105	COG3537	Alpha-1,2-mannosidase
RAM_08110	COG3537	Alpha-1,2-mannosidase
RAM_08120	COG1846	Transcriptional regulator
RAM_08145	COG0058	SHG alpha-glucan phosphorylase activity
RAM_08170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_08190	COG1119	ATPase activity
RAM_08195	COG1024	Enoyl-CoA hydratase
RAM_08200	COG2226	methyltransferase
RAM_08220	COG3979	chitinase
RAM_08230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_08265	COG0667	Aldo Keto reductase
RAM_08270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_08275	COG3883	PFAM NLP P60 protein
RAM_08275	COG0791	NLP P60 protein
RAM_08280	COG1957	nucleoside hydrolase
RAM_08285	COG0110	maltose O-acetyltransferase activity
RAM_08370	COG3250	beta-galactosidase activity
RAM_08375	COG0386	Belongs to the glutathione peroxidase family
RAM_08385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RAM_08395	COG1307	EDD domain protein, DegV family
RAM_08405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RAM_08425	COG2197	response regulator
RAM_08440	COG0482	sulfurtransferase activity
RAM_08460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_08480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RAM_08495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RAM_08500	COG0154	amidase activity
RAM_08505	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RAM_08530	COG0673	inositol 2-dehydrogenase activity
RAM_08540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RAM_08550	COG0129	dihydroxy-acid dehydratase activity
RAM_08565	COG0440	acetolactate synthase activity
RAM_08570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RAM_08610	COG1404	Belongs to the peptidase S8 family
RAM_08615	COG0473	3-isopropylmalate dehydrogenase activity
RAM_08620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RAM_08625	COG0179	Fumarylacetoacetate (FAA) hydrolase
RAM_08645	COG3903	Transcriptional regulator
RAM_08645	COG3629	intracellular signal transduction
RAM_08700	COG0776	regulation of translation
RAM_08710	COG0420	3'-5' exonuclease activity
RAM_08715	COG0419	ATPase involved in DNA repair
RAM_08750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RAM_08755	COG0066	3-isopropylmalate dehydratase activity
RAM_08765	COG3903	Transcriptional regulator
RAM_08765	COG3629	intracellular signal transduction
RAM_08790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RAM_08800	COG0252	asparaginase activity
RAM_08810	COG1477	protein flavinylation
RAM_08825	COG0745	RESPONSE REGULATOR receiver
RAM_08830	COG2205	protein histidine kinase activity
RAM_08840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_08870	COG3345	alpha-galactosidase
RAM_08875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RAM_08880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RAM_08890	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RAM_08895	COG1461	Dihydroxyacetone kinase
RAM_08925	COG1404	Belongs to the peptidase S8 family
RAM_08930	COG5433	transposase activity
RAM_08940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RAM_09010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RAM_09035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_09045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_09050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_09060	COG0542	response to heat
RAM_09065	COG4249	Peptidase C14 caspase catalytic subunit p20
RAM_09065	COG2319	Wd-40 repeat
RAM_09070	COG3973	AAA domain
RAM_09075	COG0742	ribosomal rna small subunit methyltransferase
RAM_09080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RAM_09110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RAM_09115	COG0571	ribonuclease III activity
RAM_09125	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RAM_09145	COG3386	PFAM SMP-30 Gluconolaconase
RAM_09175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RAM_09180	COG1012	belongs to the aldehyde dehydrogenase family
RAM_09200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RAM_09200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RAM_09205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RAM_09210	COG0509	glycine decarboxylation via glycine cleavage system
RAM_09215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RAM_09220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RAM_09225	COG1760	l-serine dehydratase
RAM_09245	COG2186	Transcriptional regulator
RAM_09255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RAM_09265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_09295	COG0789	Transcriptional regulator
RAM_09305	COG2814	Major facilitator Superfamily
RAM_09310	COG0179	Fumarylacetoacetate (FAA) hydrolase
RAM_09315	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_09320	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_09330	COG1129	ABC transporter
RAM_09335	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_09340	COG2186	Transcriptional regulator
RAM_09385	COG1929	Belongs to the glycerate kinase type-1 family
RAM_09390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RAM_09400	COG1940	carbohydrate kinase activity
RAM_09405	COG1653	transport
RAM_09415	COG0395	ABC-type sugar transport system, permease component
RAM_09420	COG3345	alpha-galactosidase
RAM_09425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RAM_09430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RAM_09435	COG0183	Belongs to the thiolase family
RAM_09440	COG3485	protocatechuate 3,4-dioxygenase
RAM_09445	COG3485	protocatechuate 3,4-dioxygenase
RAM_09450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RAM_09460	COG1414	Transcriptional regulator
RAM_09465	COG0746	molybdenum cofactor guanylyltransferase activity
RAM_09470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RAM_09510	COG3706	GGDEF domain
RAM_09520	COG0667	Aldo Keto reductase
RAM_09545	COG3962	Belongs to the TPP enzyme family
RAM_09550	COG3718	enzyme involved in inositol metabolism
RAM_09560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_09580	COG1082	Xylose isomerase domain protein TIM barrel
RAM_09590	COG0673	inositol 2-dehydrogenase activity
RAM_09595	COG0367	asparagine synthase
RAM_09605	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RAM_09610	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RAM_09615	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RAM_09650	COG1254	Belongs to the acylphosphatase family
RAM_09665	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_09670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RAM_09690	COG1414	Transcriptional regulator
RAM_09730	COG3835	regulator
RAM_09750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_09755	COG3345	alpha-galactosidase
RAM_09760	COG1309	transcriptional regulator
RAM_09790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RAM_09795	COG4266	Belongs to the allantoicase family
RAM_09805	COG1832	CoA-binding protein
RAM_09830	COG1595	DNA-templated transcription, initiation
RAM_09855	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RAM_09875	COG3706	GGDEF domain
RAM_09880	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_09885	COG1309	transcriptional regulator
RAM_09895	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RAM_09905	COG1132	(ABC) transporter
RAM_09930	COG0228	four-way junction DNA binding
RAM_09950	COG0336	Belongs to the RNA methyltransferase TrmD family
RAM_09955	COG0335	large ribosomal subunit rRNA binding
RAM_09960	COG0681	Belongs to the peptidase S26 family
RAM_09965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RAM_09975	COG0792	nuclease activity
RAM_09980	COG0606	chelatase, subunit chli
RAM_10000	COG1191	sigma factor activity
RAM_10010	COG0052	Belongs to the universal ribosomal protein uS2 family
RAM_10015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RAM_10020	COG0528	UMP kinase activity
RAM_10025	COG0233	cytoplasmic translational termination
RAM_10045	COG1695	Transcriptional regulator
RAM_10050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_10055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_10060	COG1120	ATPase activity
RAM_10065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RAM_10070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RAM_10080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RAM_10130	COG0402	S-adenosylhomocysteine deaminase activity
RAM_10145	COG0402	S-adenosylhomocysteine deaminase activity
RAM_10190	COG0789	Transcriptional regulator
RAM_10210	COG3795	YCII-related domain
RAM_10230	COG1476	TRANSCRIPTIONal
RAM_10240	COG3795	YCII-related domain
RAM_10245	COG4941	Belongs to the sigma-70 factor family
RAM_10265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RAM_10275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RAM_10280	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_10310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RAM_10325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RAM_10335	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RAM_10340	COG0750	zinc metalloprotease
RAM_10345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RAM_10375	COG0454	-acetyltransferase
RAM_10375	COG0456	acetyltransferase
RAM_10410	COG2186	Transcriptional regulator
RAM_10450	COG0513	Belongs to the DEAD box helicase family
RAM_10490	COG0583	DNA-binding transcription factor activity
RAM_10500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RAM_10505	COG3022	response to hydroperoxide
RAM_10545	COG0442	prolyl-tRNA aminoacylation
RAM_10560	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RAM_10615	COG1017	nitric oxide dioxygenase activity
RAM_10615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RAM_10625	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RAM_10630	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RAM_10635	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RAM_10680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_10700	COG4152	abc transporter atp-binding protein
RAM_10705	COG1668	transmembrane transport
RAM_10715	COG3201	nicotinamide mononucleotide transporter
RAM_10720	COG1620	l-lactate permease
RAM_10730	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_10740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RAM_10870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RAM_10900	COG0477	Major facilitator Superfamily
RAM_10920	COG1960	acyl-CoA dehydrogenase activity
RAM_10930	COG1104	cysteine desulfurase activity
RAM_10940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RAM_10960	COG1113	amino acid transport
RAM_10965	COG2186	Transcriptional regulator
RAM_10970	COG0587	DNA-directed DNA polymerase activity
RAM_10975	COG0477	Major facilitator Superfamily
RAM_10995	COG0586	Pfam SNARE associated Golgi protein
RAM_11000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RAM_11015	COG1309	transcriptional regulator
RAM_11025	COG0321	lipoyl(octanoyl) transferase activity
RAM_11035	COG1090	epimerase
RAM_11050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RAM_11100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RAM_11110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RAM_11110	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RAM_11125	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RAM_11130	COG0667	Aldo Keto reductase
RAM_11170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RAM_11205	COG1845	cytochrome c oxidase, subunit III
RAM_11210	COG2010	Cytochrome c
RAM_11220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RAM_11255	COG0438	transferase activity, transferring glycosyl groups
RAM_11270	COG2124	cytochrome p450
RAM_11275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_11280	COG0659	secondary active sulfate transmembrane transporter activity
RAM_11285	COG0659	secondary active sulfate transmembrane transporter activity
RAM_11290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RAM_11310	COG0501	Belongs to the peptidase M48B family
RAM_11315	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RAM_11325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RAM_11330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RAM_11335	COG0157	Belongs to the NadC ModD family
RAM_11340	COG1404	Belongs to the peptidase S8 family
RAM_11380	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_11400	COG1674	ftsk spoiiie
RAM_11425	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RAM_11435	COG5520	Belongs to the glycosyl hydrolase 30 family
RAM_11450	COG4566	intracellular signal transduction
RAM_11455	COG2197	response regulator
RAM_11465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RAM_11475	COG0131	Imidazoleglycerol-phosphate dehydratase
RAM_11495	COG2267	carboxylic ester hydrolase activity
RAM_11500	COG2409	Drug exporters of the RND superfamily
RAM_11505	COG1309	transcriptional regulator
RAM_11510	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
RAM_11520	COG3959	Transketolase, thiamine diphosphate binding domain
RAM_11525	COG3958	Transketolase
RAM_11540	COG1960	acyl-CoA dehydrogenase activity
RAM_11555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RAM_11560	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RAM_11620	COG0107	imidazoleglycerol-phosphate synthase activity
RAM_11630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RAM_11665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RAM_11675	COG0134	indole-3-glycerol-phosphate synthase activity
RAM_11680	COG0133	tryptophan synthase activity
RAM_11685	COG0159	tryptophan synthase activity
RAM_11690	COG0789	Transcriptional regulator
RAM_11710	COG0174	glutamine synthetase
RAM_11725	COG1473	amidohydrolase
RAM_11730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RAM_11740	COG0070	glutamate synthase
RAM_11740	COG0067	glutamate synthase
RAM_11740	COG0069	glutamate synthase activity
RAM_11760	COG0596	Alpha beta hydrolase
RAM_11765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RAM_11780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_11790	COG2268	Band 7 protein
RAM_11800	COG0515	serine threonine protein kinase
RAM_11800	COG2815	serine threonine protein kinase
RAM_11885	COG0242	peptide deformylase activity
RAM_11890	COG1201	RNA secondary structure unwinding
RAM_11895	COG1349	DNA-binding transcription factor activity
RAM_11905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RAM_11920	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RAM_11925	COG2137	regulation of response to DNA damage stimulus
RAM_11945	COG0800	Aldolase
RAM_11965	COG1053	succinate dehydrogenase
RAM_12000	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_12005	COG0765	amino acid transport
RAM_12010	COG0765	amino acid transport
RAM_12015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_12020	COG1126	abc transporter atp-binding protein
RAM_12030	COG3850	Histidine kinase
RAM_12030	COG0642	Histidine kinase
RAM_12040	COG1733	regulation of RNA biosynthetic process
RAM_12105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RAM_12125	COG1196	nuclear chromosome segregation
RAM_12130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RAM_12140	COG0525	valine-tRNA ligase activity
RAM_12155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RAM_12175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RAM_12180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RAM_12200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RAM_12210	COG1505	serine-type exopeptidase activity
RAM_12245	COG2936	dipeptidyl-peptidase activity
RAM_12250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RAM_12260	COG2197	response regulator
RAM_12265	COG4585	Histidine kinase
RAM_12280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RAM_12285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RAM_12300	COG0123	including yeast histone deacetylase and acetoin utilization protein
RAM_12315	COG1960	acyl-CoA dehydrogenase activity
RAM_12320	COG1960	acyl-CoA dehydrogenase activity
RAM_12330	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_12340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_12345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_12395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_12410	COG1609	Transcriptional regulator
RAM_12425	COG0395	ABC-type sugar transport system, permease component
RAM_12430	COG2723	6-phospho-beta-galactosidase activity
RAM_12455	COG0003	Pfam Anion-transporting ATPase
RAM_12465	COG1940	carbohydrate kinase activity
RAM_12480	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_12505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RAM_12540	COG0640	Transcriptional regulator
RAM_12560	COG1946	Acyl-CoA thioesterase
RAM_12580	COG2197	response regulator
RAM_12585	COG1012	belongs to the aldehyde dehydrogenase family
RAM_12600	COG1960	acyl-CoA dehydrogenase activity
RAM_12605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_12635	COG1566	PFAM secretion protein HlyD family protein
RAM_12650	COG1309	transcriptional regulator
RAM_12655	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_12670	COG2018	Roadblock/LC7 domain
RAM_12700	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RAM_12700	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RAM_12700	COG1703	isobutyryl-CoA mutase activity
RAM_12710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_12715	COG1309	transcriptional regulator
RAM_12720	COG1960	acyl-CoA dehydrogenase activity
RAM_12725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RAM_12740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_12745	COG0748	coenzyme F420 binding
RAM_12755	COG1960	acyl-CoA dehydrogenase activity
RAM_12760	COG1960	acyl-CoA dehydrogenase activity
RAM_12765	COG2030	dehydratase
RAM_12785	COG0196	riboflavin kinase activity
RAM_12820	COG1960	acyl-CoA dehydrogenase activity
RAM_12825	COG2267	carboxylic ester hydrolase activity
RAM_12830	COG0346	lactoylglutathione lyase activity
RAM_12835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RAM_12860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RAM_12880	COG0583	DNA-binding transcription factor activity
RAM_12890	COG0446	pyridine nucleotide-disulphide oxidoreductase
RAM_12950	COG1228	amidohydrolase
RAM_12955	COG0596	Alpha beta hydrolase
RAM_12960	COG0183	Belongs to the thiolase family
RAM_12965	COG2124	cytochrome p450
RAM_12980	COG1295	ribonuclease BN
RAM_13010	COG2070	2-Nitropropane dioxygenase
RAM_13025	COG2188	Transcriptional regulator
RAM_13045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RAM_13045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RAM_13055	COG1490	D-aminoacyl-tRNA deacylase activity
RAM_13060	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_13065	COG1473	amidohydrolase
RAM_13080	COG2313	pseudouridylate synthase activity
RAM_13105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RAM_13120	COG4213	ABC transporter substrate-binding protein
RAM_13130	COG4214	carbohydrate transport
RAM_13160	COG0531	amino acid
RAM_13190	COG0366	Alpha amylase catalytic
RAM_13195	COG0366	Alpha amylase catalytic
RAM_13205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RAM_13220	COG1940	carbohydrate kinase activity
RAM_13225	COG0483	inositol monophosphate 1-phosphatase activity
RAM_13245	COG0756	dUTP diphosphatase activity
RAM_13275	COG0569	domain protein
RAM_13280	COG0531	amino acid
RAM_13285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RAM_13300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RAM_13305	COG1609	Transcriptional regulator
RAM_13315	COG1012	belongs to the aldehyde dehydrogenase family
RAM_13320	COG0028	Belongs to the TPP enzyme family
RAM_13340	COG0745	RESPONSE REGULATOR receiver
RAM_13345	COG2205	protein histidine kinase activity
RAM_13365	COG1024	Enoyl-CoA hydratase
RAM_13365	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_13370	COG0183	Belongs to the thiolase family
RAM_13395	COG0439	Biotin carboxylase
RAM_13410	COG0531	amino acid
RAM_13415	COG1309	transcriptional regulator
RAM_13425	COG2197	response regulator
RAM_13435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RAM_13450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_13460	COG3220	belongs to the UPF0276 family
RAM_13475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RAM_13505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_13510	COG0539	negative regulation of cytoplasmic translation
RAM_13520	COG2508	Transcriptional regulator
RAM_13520	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RAM_13525	COG1012	belongs to the aldehyde dehydrogenase family
RAM_13540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RAM_13550	COG3795	YCII-related domain
RAM_13560	COG4941	Belongs to the sigma-70 factor family
RAM_13570	COG1793	dna ligase
RAM_13595	COG1302	Protein conserved in bacteria
RAM_13605	COG1595	DNA-templated transcription, initiation
RAM_13640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RAM_13645	COG0640	Transcriptional regulator
RAM_13655	COG2326	polyphosphate kinase activity
RAM_13670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RAM_13675	COG1993	acr, cog1993
RAM_13680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RAM_13710	COG1672	PFAM Archaeal ATPase
RAM_13710	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RAM_13735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RAM_13760	COG2124	cytochrome p450
RAM_13780	COG2084	Dehydrogenase
RAM_13795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RAM_13805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RAM_13810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RAM_13815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RAM_13820	COG1309	transcriptional regulator
RAM_13830	COG1073	alpha beta
RAM_13840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RAM_13850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RAM_13855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RAM_13855	COG1263	PTS System
RAM_13865	COG1263	PTS System
RAM_13865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RAM_13870	COG1263	PTS System
RAM_13870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RAM_13870	COG2190	(PTS) system
RAM_13895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RAM_13900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RAM_13905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RAM_13910	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RAM_13915	COG0346	lactoylglutathione lyase activity
RAM_13930	COG0006	proline dipeptidase activity
RAM_13935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RAM_13940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RAM_13960	COG0540	Belongs to the ATCase OTCase family
RAM_13975	COG0505	Belongs to the CarA family
RAM_13980	COG0419	ATPase involved in DNA repair
RAM_13995	COG0284	orotidine-5'-phosphate decarboxylase activity
RAM_14005	COG0194	GDP metabolic process
RAM_14010	COG1758	RNA polymerase activity
RAM_14020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RAM_14045	COG0405	Gamma-glutamyltransferase
RAM_14050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RAM_14075	COG2197	response regulator
RAM_14080	COG4585	Histidine kinase
RAM_14095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_14095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_14100	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RAM_14120	COG0322	excinuclease ABC activity
RAM_14125	COG1660	Displays ATPase and GTPase activities
RAM_14135	COG1481	regulation of sporulation
RAM_14140	COG0463	Glycosyl transferase, family 2
RAM_14165	COG3250	beta-galactosidase activity
RAM_14170	COG0408	coproporphyrinogen oxidase activity
RAM_14210	COG1280	lysine exporter protein (LysE YggA)
RAM_14220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RAM_14225	COG0126	phosphoglycerate kinase activity
RAM_14230	COG0149	triose-phosphate isomerase activity
RAM_14250	COG0363	glucosamine-6-phosphate deaminase activity
RAM_14265	COG0166	Belongs to the GPI family
RAM_14270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RAM_14280	COG0109	protoheme IX farnesyltransferase activity
RAM_14390	COG0396	ATPase activity
RAM_14405	COG2151	metal-sulfur cluster biosynthetic enzyme
RAM_14415	COG1742	UPF0060 membrane protein
RAM_14425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RAM_14435	COG4585	Histidine kinase
RAM_14445	COG2226	methyltransferase
RAM_14480	COG0457	Tetratricopeptide repeat
RAM_14570	COG1132	(ABC) transporter
RAM_14580	COG4821	SIS domain
RAM_14590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_14595	COG1316	TRANSCRIPTIONal
RAM_14600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_14610	COG5001	Diguanylate cyclase
RAM_14610	COG3300	MHYT domain
RAM_14625	COG1051	belongs to the nudix hydrolase family
RAM_14635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RAM_14635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RAM_14645	COG1024	Enoyl-CoA hydratase
RAM_14670	COG1960	acyl-CoA dehydrogenase activity
RAM_14675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_14690	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_14715	COG3469	chitinase activity
RAM_14755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_14765	COG3693	PFAM glycoside hydrolase, family 10
RAM_14795	COG1309	transcriptional regulator
RAM_14800	COG0789	Transcriptional regulator
RAM_14815	COG4249	Peptidase C14 caspase catalytic subunit p20
RAM_14815	COG2319	Wd-40 repeat
RAM_14835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_14905	COG2197	response regulator
RAM_14975	COG0300	oxidoreductase activity
RAM_14985	COG1846	Transcriptional regulator
RAM_15000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_15015	COG1595	DNA-templated transcription, initiation
RAM_15035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RAM_15040	COG1799	cell septum assembly
RAM_15050	COG3599	regulation of cell shape
RAM_15060	COG0640	Transcriptional regulator
RAM_15065	COG0477	Major facilitator Superfamily
RAM_15070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RAM_15080	COG0640	Transcriptional regulator
RAM_15085	COG3263	regulation of cellular component size
RAM_15090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RAM_15100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RAM_15125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_15135	COG0248	Ppx GppA phosphatase
RAM_15180	COG1846	Transcriptional regulator
RAM_15180	COG1940	carbohydrate kinase activity
RAM_15190	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
RAM_15215	COG2010	Cytochrome c
RAM_15215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_15240	COG1309	transcriptional regulator
RAM_15245	COG4221	oxidoreductase activity
RAM_15250	COG0667	Aldo Keto reductase
RAM_15255	COG0542	response to heat
RAM_15265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RAM_15275	COG0514	ATP-dependent DNA helicase (RecQ)
RAM_15285	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_15320	COG2205	protein histidine kinase activity
RAM_15325	COG0745	RESPONSE REGULATOR receiver
RAM_15335	COG0076	glutamate decarboxylase activity
RAM_15390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RAM_15400	COG1131	(ABC) transporter
RAM_15420	COG0604	alcohol dehydrogenase
RAM_15430	COG2764	glyoxalase bleomycin resistance protein dioxygenase
RAM_15450	COG4585	Histidine kinase
RAM_15460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_15465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RAM_15470	COG2080	2 iron, 2 sulfur cluster binding
RAM_15495	COG2188	Transcriptional regulator
RAM_15505	COG1063	alcohol dehydrogenase
RAM_15520	COG2172	sigma factor antagonist activity
RAM_15525	COG1366	Belongs to the anti-sigma-factor antagonist family
RAM_15530	COG1366	Belongs to the anti-sigma-factor antagonist family
RAM_15555	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_15560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RAM_15570	COG3546	catalase activity
RAM_15580	COG0702	epimerase
RAM_15585	COG1733	regulation of RNA biosynthetic process
RAM_15615	COG1609	Transcriptional regulator
RAM_15625	COG1175	transmembrane transport
RAM_15630	COG0395	ABC-type sugar transport system, permease component
RAM_15650	COG0667	Aldo Keto reductase
RAM_15660	COG0667	Aldo Keto reductase
RAM_15670	COG2378	regulation of single-species biofilm formation
RAM_15680	COG1691	(AIR) carboxylase
RAM_15685	COG3875	lactate racemase activity
RAM_15690	COG3618	amidohydrolase
RAM_15695	COG0179	Fumarylacetoacetate (FAA) hydrolase
RAM_15700	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_15715	COG1129	ABC transporter
RAM_15755	COG1609	Transcriptional regulator
RAM_15760	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_15780	COG3251	PFAM MbtH domain protein
RAM_15800	COG2124	cytochrome p450
RAM_15825	COG0604	alcohol dehydrogenase
RAM_15840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_15895	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_15915	COG3250	beta-galactosidase activity
RAM_15925	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_15930	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_15940	COG1309	transcriptional regulator
RAM_15955	COG1960	acyl-CoA dehydrogenase activity
RAM_15960	COG1960	acyl-CoA dehydrogenase activity
RAM_15985	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_16000	COG0395	ABC-type sugar transport system, permease component
RAM_16005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RAM_16010	COG0515	serine threonine protein kinase
RAM_16050	COG2814	Major facilitator Superfamily
RAM_16060	COG5002	protein histidine kinase activity
RAM_16065	COG0745	RESPONSE REGULATOR receiver
RAM_16080	COG1131	(ABC) transporter
RAM_16100	COG1309	transcriptional regulator
RAM_16125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RAM_16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_16140	COG1595	DNA-templated transcription, initiation
RAM_16160	COG0596	Alpha beta hydrolase
RAM_16170	COG0477	Major facilitator Superfamily
RAM_16215	COG0366	Alpha amylase catalytic
RAM_16235	COG1175	transmembrane transport
RAM_16250	COG1349	DNA-binding transcription factor activity
RAM_16260	COG1609	Transcriptional regulator
RAM_16265	COG0515	serine threonine protein kinase
RAM_16265	COG2815	serine threonine protein kinase
RAM_16270	COG2815	serine threonine protein kinase
RAM_16270	COG0515	serine threonine protein kinase
RAM_16285	COG0437	4 iron, 4 sulfur cluster binding
RAM_16290	COG0243	molybdopterin cofactor binding
RAM_16290	COG3383	formate dehydrogenase (NAD+) activity
RAM_16295	COG0243	molybdopterin cofactor binding
RAM_16300	COG2271	Major facilitator Superfamily
RAM_16315	COG2318	DinB family
RAM_16345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RAM_16355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_16360	COG0583	DNA-binding transcription factor activity
RAM_16370	COG1053	succinate dehydrogenase
RAM_16375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RAM_16410	COG3511	phospholipase C
RAM_16450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RAM_16455	COG3938	Belongs to the proline racemase family
RAM_16465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_16465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_16475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_16485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_16490	COG0395	ABC-type sugar transport system, permease component
RAM_16495	COG1175	transmembrane transport
RAM_16545	COG0628	permease
RAM_16550	COG3507	Belongs to the glycosyl hydrolase 43 family
RAM_16560	COG1793	dna ligase
RAM_16560	COG3285	dna ligase
RAM_16575	COG2226	methyltransferase
RAM_16580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RAM_16620	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_16625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_16630	COG1024	Enoyl-CoA hydratase
RAM_16645	COG1012	belongs to the aldehyde dehydrogenase family
RAM_16715	COG3507	Belongs to the glycosyl hydrolase 43 family
RAM_16790	COG1309	transcriptional regulator
RAM_16795	COG1595	DNA-templated transcription, initiation
RAM_16810	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_16815	COG0028	Belongs to the TPP enzyme family
RAM_16830	COG2018	Roadblock/LC7 domain
RAM_16850	COG2188	Transcriptional regulator
RAM_16855	COG3525	Glycosyl hydrolase, family 20, catalytic domain
RAM_16860	COG0395	ABC-type sugar transport system, permease component
RAM_16865	COG1175	transmembrane transport
RAM_16880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RAM_16915	COG0745	RESPONSE REGULATOR receiver
RAM_16915	COG3706	GGDEF domain
RAM_16920	COG1609	Transcriptional regulator
RAM_16960	COG3591	Belongs to the peptidase S1B family
RAM_16985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_17020	COG2267	carboxylic ester hydrolase activity
RAM_17050	COG2357	RelA SpoT domain protein
RAM_17075	COG1280	lysine exporter protein (LysE YggA)
RAM_17080	COG0484	heat shock protein binding
RAM_17085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_17110	COG2409	Drug exporters of the RND superfamily
RAM_17120	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_17130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_17180	COG1024	Enoyl-CoA hydratase
RAM_17200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_17205	COG0183	Belongs to the thiolase family
RAM_17215	COG1960	acyl-CoA dehydrogenase activity
RAM_17220	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_17225	COG1024	Enoyl-CoA hydratase
RAM_17230	COG1960	acyl-CoA dehydrogenase activity
RAM_17235	COG1960	acyl-CoA dehydrogenase activity
RAM_17240	COG1960	acyl-CoA dehydrogenase activity
RAM_17255	COG1802	Transcriptional regulator
RAM_17260	COG3591	Belongs to the peptidase S1B family
RAM_17260	COG1864	DNA RNA non-specific endonuclease
RAM_17275	COG1063	alcohol dehydrogenase
RAM_17280	COG2267	carboxylic ester hydrolase activity
RAM_17300	COG1309	transcriptional regulator
RAM_17305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_17320	COG3345	alpha-galactosidase
RAM_17335	COG1175	transmembrane transport
RAM_17340	COG0395	ABC-type sugar transport system, permease component
RAM_17375	COG0477	Major facilitator Superfamily
RAM_17390	COG1940	carbohydrate kinase activity
RAM_17395	COG0531	amino acid
RAM_17400	COG3250	beta-galactosidase activity
RAM_17405	COG1940	carbohydrate kinase activity
RAM_17415	COG1609	Transcriptional regulator
RAM_17430	COG2124	cytochrome p450
RAM_17470	COG1846	Transcriptional regulator
RAM_17475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_17525	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_17555	COG0702	epimerase
RAM_17580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RAM_17595	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_17615	COG0601	transmembrane transport
RAM_17620	COG0444	Belongs to the ABC transporter superfamily
RAM_17625	COG4608	Belongs to the ABC transporter superfamily
RAM_17635	COG0477	Major facilitator Superfamily
RAM_17660	COG0477	Major facilitator Superfamily
RAM_17670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RAM_17690	COG3507	Belongs to the glycosyl hydrolase 43 family
RAM_17705	COG1231	oxidoreductase activity
RAM_17715	COG0235	Class ii aldolase
RAM_17715	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RAM_17730	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_17735	COG0701	Predicted permease
RAM_17760	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_17770	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_17780	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_17790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RAM_17825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RAM_17855	COG0501	Belongs to the peptidase M48B family
RAM_17890	COG0569	domain protein
RAM_17890	COG0475	glutathione-regulated potassium exporter activity
RAM_17925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RAM_17930	COG4279	zinc finger
RAM_17965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_17995	COG0069	glutamate synthase activity
RAM_18000	COG0745	RESPONSE REGULATOR receiver
RAM_18005	COG5002	protein histidine kinase activity
RAM_18020	COG1136	(ABC) transporter
RAM_18020	COG0577	efflux transmembrane transporter activity
RAM_18025	COG0577	efflux transmembrane transporter activity
RAM_18025	COG1136	(ABC) transporter
RAM_18040	COG2814	Major facilitator Superfamily
RAM_18045	COG0596	Alpha beta hydrolase
RAM_18055	COG4585	Histidine kinase
RAM_18085	COG4585	Histidine kinase
RAM_18125	COG4221	oxidoreductase activity
RAM_18130	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
RAM_18205	COG0745	RESPONSE REGULATOR receiver
RAM_18210	COG2205	protein histidine kinase activity
RAM_18230	COG0726	polysaccharide deacetylase
RAM_18285	COG1063	alcohol dehydrogenase
RAM_18350	COG4221	oxidoreductase activity
RAM_18355	COG2319	Wd-40 repeat
RAM_18355	COG4249	Peptidase C14 caspase catalytic subunit p20
RAM_18425	COG2197	response regulator
RAM_18430	COG0736	holo-[acyl-carrier-protein] synthase activity
RAM_18450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_18505	COG1834	amidinotransferase
RAM_18520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_18525	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RAM_18530	COG2080	2 iron, 2 sulfur cluster binding
RAM_18540	COG3345	alpha-galactosidase
RAM_18585	COG1309	transcriptional regulator
RAM_18615	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_18620	COG0583	DNA-binding transcription factor activity
RAM_18695	COG0583	DNA-binding transcription factor activity
RAM_18790	COG2205	protein histidine kinase activity
RAM_18825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_18870	COG1522	sequence-specific DNA binding
RAM_18935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_18945	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RAM_18950	COG2080	2 iron, 2 sulfur cluster binding
RAM_18985	COG0631	protein serine/threonine phosphatase activity
RAM_19035	COG3509	depolymerase
RAM_19055	COG0601	transmembrane transport
RAM_19065	COG4608	Belongs to the ABC transporter superfamily
RAM_19075	COG1609	Transcriptional regulator
RAM_19080	COG4124	Belongs to the glycosyl hydrolase 26 family
RAM_19090	COG1846	Transcriptional regulator
RAM_19090	COG1940	carbohydrate kinase activity
RAM_19100	COG1960	acyl-CoA dehydrogenase activity
RAM_19105	COG2207	Transcriptional regulator
RAM_19175	COG0745	RESPONSE REGULATOR receiver
RAM_19180	COG2205	protein histidine kinase activity
RAM_19190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RAM_19190	COG2755	lipolytic protein G-D-S-L family
RAM_19215	COG2267	carboxylic ester hydrolase activity
RAM_19220	COG2226	methyltransferase
RAM_19230	COG0640	Transcriptional regulator
RAM_19265	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RAM_19275	COG0375	protein maturation
RAM_19285	COG0409	Hydrogenase expression formation protein
RAM_19330	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RAM_19340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RAM_19380	COG3903	Transcriptional regulator
RAM_19380	COG3629	intracellular signal transduction
RAM_19385	COG0596	Alpha beta hydrolase
RAM_19390	COG1063	alcohol dehydrogenase
RAM_19395	COG1024	Enoyl-CoA hydratase
RAM_19395	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_19400	COG1733	regulation of RNA biosynthetic process
RAM_19430	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_19435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_19440	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_19445	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_19480	COG0411	ABC transporter
RAM_19490	COG1024	Enoyl-CoA hydratase
RAM_19495	COG1960	acyl-CoA dehydrogenase activity
RAM_19500	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_19505	COG1946	Acyl-CoA thioesterase
RAM_19515	COG1024	Enoyl-CoA hydratase
RAM_19520	COG1960	acyl-CoA dehydrogenase activity
RAM_19525	COG1012	belongs to the aldehyde dehydrogenase family
RAM_19535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_19540	COG0183	Belongs to the thiolase family
RAM_19580	COG1946	Acyl-CoA thioesterase
RAM_19600	COG1960	acyl-CoA dehydrogenase activity
RAM_19620	COG0183	Belongs to the thiolase family
RAM_19635	COG0183	Belongs to the thiolase family
RAM_19640	COG1024	Enoyl-CoA hydratase
RAM_19655	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_19670	COG1024	Enoyl-CoA hydratase
RAM_19680	COG1960	acyl-CoA dehydrogenase activity
RAM_19685	COG1960	acyl-CoA dehydrogenase activity
RAM_19690	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_19715	COG1960	acyl-CoA dehydrogenase activity
RAM_19730	COG1012	belongs to the aldehyde dehydrogenase family
RAM_19735	COG1960	acyl-CoA dehydrogenase activity
RAM_19740	COG1960	acyl-CoA dehydrogenase activity
RAM_19745	COG1024	Enoyl-CoA hydratase
RAM_19750	COG2188	Transcriptional regulator
RAM_19755	COG0300	oxidoreductase activity
RAM_19760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RAM_19790	COG1309	transcriptional regulator
RAM_19800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_19805	COG3629	intracellular signal transduction
RAM_19805	COG3903	Transcriptional regulator
RAM_19825	COG1017	nitric oxide dioxygenase activity
RAM_19825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RAM_19830	COG1846	Transcriptional regulator
RAM_19830	COG1940	carbohydrate kinase activity
RAM_19840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RAM_19850	COG0531	amino acid
RAM_19855	COG3387	PFAM Glycoside hydrolase 15-related
RAM_19860	COG2814	Major facilitator Superfamily
RAM_19880	COG2197	response regulator
RAM_19915	COG0628	permease
RAM_19935	COG1486	melibiose metabolic process
RAM_19940	COG0395	ABC-type sugar transport system, permease component
RAM_19960	COG1349	DNA-binding transcription factor activity
RAM_19965	COG2222	sugar isomerase
RAM_19985	COG1105	Belongs to the carbohydrate kinase PfkB family
RAM_20055	COG0596	Alpha beta hydrolase
RAM_20065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RAM_20065	COG1024	Enoyl-CoA hydratase
RAM_20070	COG3903	Transcriptional regulator
RAM_20070	COG3629	intracellular signal transduction
RAM_20080	COG1132	(ABC) transporter
RAM_20110	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_20130	COG4221	oxidoreductase activity
RAM_20135	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_20140	COG0395	ABC-type sugar transport system, permease component
RAM_20145	COG3833	ABC-type maltose transport systems, permease component
RAM_20180	COG2124	cytochrome p450
RAM_20185	COG2175	clavaminate synthase activity
RAM_20200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_20205	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_20250	COG1940	carbohydrate kinase activity
RAM_20255	COG1846	Transcriptional regulator
RAM_20255	COG1940	carbohydrate kinase activity
RAM_20270	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_20280	COG0673	inositol 2-dehydrogenase activity
RAM_20290	COG0604	alcohol dehydrogenase
RAM_20370	COG1064	alcohol dehydrogenase
RAM_20375	COG1309	transcriptional regulator
RAM_20380	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_20395	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RAM_20400	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_20420	COG2508	Transcriptional regulator
RAM_20425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_20435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_20440	COG0463	Glycosyl transferase, family 2
RAM_20450	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_20460	COG3629	intracellular signal transduction
RAM_20465	COG0583	DNA-binding transcription factor activity
RAM_20475	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_20485	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_20490	COG1846	Transcriptional regulator
RAM_20495	COG3903	Transcriptional regulator
RAM_20495	COG3629	intracellular signal transduction
RAM_20500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_20515	COG2197	response regulator
RAM_20525	COG0577	efflux transmembrane transporter activity
RAM_20525	COG1136	(ABC) transporter
RAM_20555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_20585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_20600	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_20610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RAM_20615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_20620	COG3629	intracellular signal transduction
RAM_20620	COG3903	Transcriptional regulator
RAM_20625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RAM_20645	COG3509	depolymerase
RAM_20650	COG2205	protein histidine kinase activity
RAM_20655	COG0745	RESPONSE REGULATOR receiver
RAM_20660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RAM_20670	COG0583	DNA-binding transcription factor activity
RAM_20695	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_20725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_20815	COG0395	ABC-type sugar transport system, permease component
RAM_20835	COG1609	Transcriptional regulator
RAM_20865	COG0653	protein targeting
RAM_20910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_20920	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
RAM_20940	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RAM_20945	COG1012	belongs to the aldehyde dehydrogenase family
RAM_20950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RAM_20985	COG3661	Belongs to the glycosyl hydrolase 67 family
RAM_21000	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_21040	COG2201	protein-glutamate methylesterase activity
RAM_21045	COG2201	protein-glutamate methylesterase activity
RAM_21065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RAM_21110	COG0477	Major facilitator Superfamily
RAM_21125	COG2318	DinB family
RAM_21130	COG1793	dna ligase
RAM_21160	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
RAM_21170	COG2814	Major facilitator Superfamily
RAM_21180	COG2855	membrane
RAM_21190	COG0583	DNA-binding transcription factor activity
RAM_21220	COG0439	Biotin carboxylase
RAM_21260	COG0477	Major facilitator Superfamily
RAM_21285	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_21310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RAM_21340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_21375	COG1793	dna ligase
RAM_21375	COG3285	dna ligase
RAM_21405	COG2267	carboxylic ester hydrolase activity
RAM_21440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RAM_21455	COG3634	alkyl hydroperoxide reductase activity
RAM_21475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RAM_21535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RAM_21550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RAM_21560	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_21580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_21585	COG2124	cytochrome p450
RAM_21595	COG2201	protein-glutamate methylesterase activity
RAM_21615	COG0515	serine threonine protein kinase
RAM_21615	COG2815	serine threonine protein kinase
RAM_21625	COG0326	Molecular chaperone. Has ATPase activity
RAM_21635	COG3794	PFAM blue (type 1) copper domain protein
RAM_21700	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_21715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RAM_21740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RAM_21750	COG0300	oxidoreductase activity
RAM_21755	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RAM_21755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RAM_21760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RAM_21765	COG2192	nodulation
RAM_21770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RAM_21785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RAM_21785	COG0463	Glycosyl transferase, family 2
RAM_21790	COG0297	glycogen (starch) synthase activity
RAM_21835	COG1959	2 iron, 2 sulfur cluster binding
RAM_21835	COG1295	ribonuclease BN
RAM_21860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RAM_21860	COG0723	plastoquinol--plastocyanin reductase activity
RAM_21865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RAM_21875	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_21890	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_21900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_21910	COG1982	Orn Lys Arg decarboxylase major
RAM_21930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_21955	COG0596	Alpha beta hydrolase
RAM_21980	COG3835	regulator
RAM_22005	COG3284	Transcriptional regulator
RAM_22050	COG0459	protein refolding
RAM_22080	COG0596	Alpha beta hydrolase
RAM_22085	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_22090	COG0435	Glutathione S-transferase
RAM_22100	COG2353	YceI-like domain
RAM_22105	COG1309	transcriptional regulator
RAM_22120	COG0395	ABC-type sugar transport system, permease component
RAM_22135	COG1609	Transcriptional regulator
RAM_22145	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_22155	COG2124	cytochrome p450
RAM_22165	COG1716	ATPase activity
RAM_22165	COG5001	Diguanylate cyclase
RAM_22180	COG0247	lactate metabolic process
RAM_22180	COG2181	nitrate reductase activity
RAM_22185	COG1716	ATPase activity
RAM_22195	COG0477	Major facilitator Superfamily
RAM_22205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RAM_22230	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_22240	COG4991	sh3 domain protein
RAM_22325	COG0302	gtp cyclohydrolase
RAM_22340	COG1609	Transcriptional regulator
RAM_22365	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_22380	COG1686	Belongs to the peptidase S11 family
RAM_22390	COG1609	Transcriptional regulator
RAM_22395	COG1879	ABC-type sugar transport system periplasmic component
RAM_22405	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_22410	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_22430	COG2160	L-arabinose isomerase activity
RAM_22440	COG1129	ABC transporter
RAM_22445	COG4214	carbohydrate transport
RAM_22455	COG1609	Transcriptional regulator
RAM_22465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RAM_22470	COG1414	Transcriptional regulator
RAM_22480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RAM_22485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RAM_22495	COG0137	argininosuccinate synthase activity
RAM_22540	COG0277	FAD linked oxidase domain protein
RAM_22545	COG1609	Transcriptional regulator
RAM_22555	COG1653	transport
RAM_22560	COG1175	transmembrane transport
RAM_22565	COG0395	ABC-type sugar transport system, permease component
RAM_22575	COG0673	inositol 2-dehydrogenase activity
RAM_22580	COG0673	inositol 2-dehydrogenase activity
RAM_22590	COG3866	Pectate lyase
RAM_22620	COG3903	Transcriptional regulator
RAM_22620	COG3629	intracellular signal transduction
RAM_22635	COG0589	response to stress
RAM_22640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RAM_22700	COG1090	epimerase
RAM_22735	COG0297	glycogen (starch) synthase activity
RAM_22760	COG3250	beta-galactosidase activity
RAM_22775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RAM_22820	COG0477	Major facilitator Superfamily
RAM_22825	COG3321	synthase
RAM_22825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_22830	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_22845	COG0300	oxidoreductase activity
RAM_22850	COG1819	glycosyl
RAM_22860	COG3285	dna ligase
RAM_22860	COG1793	dna ligase
RAM_22870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RAM_22885	COG2267	carboxylic ester hydrolase activity
RAM_22900	COG3903	Transcriptional regulator
RAM_22900	COG3629	intracellular signal transduction
RAM_22905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RAM_22915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RAM_22915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RAM_22915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RAM_22930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RAM_22950	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_22955	COG1609	Transcriptional regulator
RAM_22970	COG0395	ABC-type sugar transport system, permease component
RAM_22980	COG1609	Transcriptional regulator
RAM_23000	COG1278	Cold shock
RAM_23005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_23055	COG0387	Pfam Sodium calcium exchanger
RAM_23060	COG0583	DNA-binding transcription factor activity
RAM_23065	COG0028	Belongs to the TPP enzyme family
RAM_23110	COG1609	Transcriptional regulator
RAM_23115	COG1129	ABC transporter
RAM_23120	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_23125	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_23135	COG3254	rhamnose metabolic process
RAM_23145	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_23145	COG3347	Dehydrogenase
RAM_23155	COG1070	Carbohydrate kinase
RAM_23160	COG2197	response regulator
RAM_23165	COG4585	Histidine kinase
RAM_23180	COG3250	beta-galactosidase activity
RAM_23235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RAM_23240	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_23255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RAM_23270	COG0045	succinate-CoA ligase (ADP-forming) activity
RAM_23280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_23285	COG0045	succinate-CoA ligase (ADP-forming) activity
RAM_23285	COG1042	CoA-binding domain protein
RAM_23285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_23290	COG2223	nitrite transmembrane transporter activity
RAM_23295	COG1802	Transcriptional regulator
RAM_23300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RAM_23305	COG3383	formate dehydrogenase (NAD+) activity
RAM_23310	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RAM_23315	COG1034	ATP synthesis coupled electron transport
RAM_23320	COG3622	Belongs to the hyi family
RAM_23325	COG2084	Dehydrogenase
RAM_23330	COG3960	tartronate-semialdehyde synthase activity
RAM_23345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_23350	COG0590	tRNA wobble adenosine to inosine editing
RAM_23355	COG2252	PERMEase
RAM_23365	COG1929	Belongs to the glycerate kinase type-1 family
RAM_23420	COG2066	Belongs to the glutaminase family
RAM_23435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RAM_23450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_23455	COG0596	Alpha beta hydrolase
RAM_23465	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_23480	COG3285	dna ligase
RAM_23480	COG1793	dna ligase
RAM_23485	COG0183	Belongs to the thiolase family
RAM_23490	COG1733	regulation of RNA biosynthetic process
RAM_23535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_23540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_23545	COG1609	Transcriptional regulator
RAM_23555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RAM_23560	COG2267	carboxylic ester hydrolase activity
RAM_23595	COG0667	Aldo Keto reductase
RAM_23600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_23605	COG1968	undecaprenyl-diphosphatase activity
RAM_23615	COG0339	signal peptide processing
RAM_23620	COG0740	serine-type endopeptidase activity
RAM_23625	COG0039	L-malate dehydrogenase activity
RAM_23660	COG3537	Alpha-1,2-mannosidase
RAM_23700	COG0747	negative chemotaxis
RAM_23705	COG0601	transmembrane transport
RAM_23715	COG4172	Belongs to the ABC transporter superfamily
RAM_23730	COG1619	proteins homologs of microcin C7 resistance protein MccF
RAM_23735	COG4946	Tricorn protease homolog
RAM_23735	COG0823	Involved in the tonB-independent uptake of proteins
RAM_23735	COG1506	peptidase
RAM_23795	COG0477	Major facilitator Superfamily
RAM_23815	COG0640	Transcriptional regulator
RAM_23870	COG4941	Belongs to the sigma-70 factor family
RAM_23935	COG4941	Belongs to the sigma-70 factor family
RAM_23945	COG2124	cytochrome p450
RAM_23965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RAM_23980	COG1309	transcriptional regulator
RAM_23990	COG1960	acyl-CoA dehydrogenase activity
RAM_23995	COG1309	transcriptional regulator
RAM_24010	COG1396	sequence-specific DNA binding
RAM_24025	COG0640	Transcriptional regulator
RAM_24035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RAM_24060	COG1435	thymidine kinase activity
RAM_24070	COG0494	nUDIX hydrolase
RAM_24080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_24085	COG0463	Glycosyl transferase, family 2
RAM_24095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RAM_24120	COG4977	sequence-specific DNA binding
RAM_24125	COG1733	regulation of RNA biosynthetic process
RAM_24145	COG3629	intracellular signal transduction
RAM_24145	COG3903	Transcriptional regulator
RAM_24180	COG4865	methylaspartate mutase activity
RAM_24185	COG0017	Asparaginyl-tRNA synthetase
RAM_24190	COG0069	glutamate synthase activity
RAM_24205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RAM_24255	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_24280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_24305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_24365	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_24370	COG2186	Transcriptional regulator
RAM_24375	COG0395	ABC-type sugar transport system, permease component
RAM_24380	COG1175	transmembrane transport
RAM_24390	COG3293	Transposase
RAM_24410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_24420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RAM_24425	COG4865	methylaspartate mutase activity
RAM_24435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_24480	COG0789	Transcriptional regulator
RAM_24530	COG2124	cytochrome p450
RAM_24565	COG2197	response regulator
RAM_24570	COG2197	response regulator
RAM_24580	COG0823	Involved in the tonB-independent uptake of proteins
RAM_24690	COG0402	S-adenosylhomocysteine deaminase activity
RAM_24695	COG1414	Transcriptional regulator
RAM_24700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_24710	COG3485	protocatechuate 3,4-dioxygenase
RAM_24730	COG3979	chitinase
RAM_24740	COG1136	(ABC) transporter
RAM_24760	COG4221	oxidoreductase activity
RAM_24765	COG0583	DNA-binding transcription factor activity
RAM_24775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RAM_24820	COG4552	Acetyltransferase involved in intracellular survival and related
RAM_24840	COG1597	lipid kinase activity
RAM_24850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RAM_24860	COG2378	regulation of single-species biofilm formation
RAM_24870	COG1733	regulation of RNA biosynthetic process
RAM_24880	COG4221	oxidoreductase activity
RAM_24890	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RAM_24905	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RAM_24910	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RAM_24945	COG0640	Transcriptional regulator
RAM_24960	COG0697	spore germination
RAM_24965	COG1222	aaa ATPase
RAM_24990	COG0517	IMP dehydrogenase activity
RAM_24990	COG1994	Peptidase M50
RAM_25005	COG1192	Involved in chromosome partitioning
RAM_25010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RAM_25015	COG0140	phosphoribosyl-ATP diphosphatase activity
RAM_25030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RAM_25035	COG0646	methionine synthase
RAM_25035	COG1410	methionine synthase
RAM_25075	COG2814	Major facilitator Superfamily
RAM_25090	COG0488	(ABC) transporter
RAM_25095	COG0215	cysteine-tRNA ligase activity
RAM_25100	COG0789	Transcriptional regulator
RAM_25105	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RAM_25110	COG4867	von Willebrand factor, type A
RAM_25150	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RAM_25160	COG0477	Major facilitator Superfamily
RAM_25165	COG0745	RESPONSE REGULATOR receiver
RAM_25170	COG2205	protein histidine kinase activity
RAM_25185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RAM_25195	COG2304	oxidoreductase activity
RAM_25205	COG0714	Associated with various cellular activities
RAM_25210	COG0746	molybdenum cofactor guanylyltransferase activity
RAM_25215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_25220	COG3883	PFAM NLP P60 protein
RAM_25220	COG0791	NLP P60 protein
RAM_25225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RAM_25230	COG1285	pathogenesis
RAM_25240	COG1309	transcriptional regulator
RAM_25255	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
RAM_25265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RAM_25270	COG3572	ergothioneine biosynthetic process
RAM_25280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RAM_25285	COG2267	carboxylic ester hydrolase activity
RAM_25310	COG1309	transcriptional regulator
RAM_25350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RAM_25370	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RAM_25370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RAM_25390	COG0789	Transcriptional regulator
RAM_25405	COG1716	ATPase activity
RAM_25435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_25440	COG1024	Enoyl-CoA hydratase
RAM_25445	COG2267	carboxylic ester hydrolase activity
RAM_25450	COG1648	precorrin-2 dehydrogenase activity
RAM_25450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RAM_25465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RAM_25470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RAM_25480	COG0254	rRNA binding
RAM_25520	COG2211	Major facilitator Superfamily
RAM_25525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_25560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_25570	COG1116	anion transmembrane transporter activity
RAM_25575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_25580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_25585	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RAM_25610	COG1132	(ABC) transporter
RAM_25625	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RAM_25635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_25640	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_25645	COG1120	ATPase activity
RAM_25655	COG3486	L-lysine 6-monooxygenase (NADPH) activity
RAM_25690	COG0488	(ABC) transporter
RAM_25735	COG3293	Transposase
RAM_25805	COG3250	beta-galactosidase activity
RAM_25825	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_25835	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_25840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_25850	COG1116	anion transmembrane transporter activity
RAM_25850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RAM_25855	COG2205	protein histidine kinase activity
RAM_25860	COG0745	RESPONSE REGULATOR receiver
RAM_25890	COG1846	Transcriptional regulator
RAM_25895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RAM_25905	COG0028	Belongs to the TPP enzyme family
RAM_25910	COG1073	alpha beta
RAM_25915	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_25920	COG0179	Fumarylacetoacetate (FAA) hydrolase
RAM_25930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_25950	COG1129	ABC transporter
RAM_25955	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_25980	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RAM_26005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RAM_26010	COG0463	Glycosyl transferase, family 2
RAM_26045	COG4221	oxidoreductase activity
RAM_26060	COG1921	L-seryl-tRNASec selenium transferase activity
RAM_26070	COG0709	Synthesizes selenophosphate from selenide and ATP
RAM_26100	COG2367	Beta-lactamase
RAM_26105	COG2249	NAD(P)H dehydrogenase (quinone) activity
RAM_26120	COG2267	carboxylic ester hydrolase activity
RAM_26155	COG0596	Alpha beta hydrolase
RAM_26160	COG1309	transcriptional regulator
RAM_26205	COG2770	Histidine kinase
RAM_26205	COG2208	phosphoserine phosphatase activity
RAM_26215	COG2409	Drug exporters of the RND superfamily
RAM_26240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RAM_26245	COG0019	diaminopimelate decarboxylase activity
RAM_26295	COG2201	protein-glutamate methylesterase activity
RAM_26300	COG4585	Histidine kinase
RAM_26310	COG2197	response regulator
RAM_26325	COG1324	tolerance protein
RAM_26380	COG2814	Major facilitator Superfamily
RAM_26415	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RAM_26420	COG0667	Aldo Keto reductase
RAM_26445	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_26450	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RAM_26455	COG4733	cellulase activity
RAM_26455	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_26475	COG0395	ABC-type sugar transport system, permease component
RAM_26485	COG0129	dihydroxy-acid dehydratase activity
RAM_26500	COG1573	uracil-dna glycosylase
RAM_26505	COG3285	dna ligase
RAM_26505	COG1793	dna ligase
RAM_26515	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RAM_26615	COG0583	DNA-binding transcription factor activity
RAM_26620	COG0019	diaminopimelate decarboxylase activity
RAM_26645	COG0477	Major facilitator Superfamily
RAM_26650	COG0456	acetyltransferase
RAM_26660	COG4104	PAAR repeat-containing protein
RAM_26660	COG3209	COG3209 Rhs family protein
RAM_26775	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_26805	COG0456	acetyltransferase
RAM_26810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RAM_26825	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RAM_26845	COG2018	Roadblock/LC7 domain
RAM_26850	COG2205	protein histidine kinase activity
RAM_26885	COG3903	Transcriptional regulator
RAM_26885	COG3629	intracellular signal transduction
RAM_26910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_26935	COG1024	Enoyl-CoA hydratase
RAM_26935	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_26965	COG0402	S-adenosylhomocysteine deaminase activity
RAM_26970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RAM_26975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RAM_26980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RAM_26985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RAM_26990	COG1862	Preprotein translocase
RAM_26995	COG2255	four-way junction helicase activity
RAM_27000	COG0632	four-way junction helicase activity
RAM_27005	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RAM_27020	COG0217	transcriptional regulatory protein
RAM_27025	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RAM_27040	COG1396	sequence-specific DNA binding
RAM_27045	COG0644	oxidoreductase
RAM_27050	COG1960	acyl-CoA dehydrogenase activity
RAM_27070	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
RAM_27080	COG0277	FAD linked oxidase domain protein
RAM_27090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RAM_27090	COG3608	succinylglutamate desuccinylase aspartoacylase
RAM_27110	COG0438	transferase activity, transferring glycosyl groups
RAM_27135	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RAM_27140	COG0778	Nitroreductase
RAM_27165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_27170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_27180	COG0701	Predicted permease
RAM_27200	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_27210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_27225	COG1473	amidohydrolase
RAM_27240	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RAM_27265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_27275	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_27350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RAM_27355	COG0395	ABC-type sugar transport system, permease component
RAM_27360	COG1175	transmembrane transport
RAM_27375	COG2072	flavoprotein involved in K transport
RAM_27390	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_27445	COG2211	Major facilitator Superfamily
RAM_27450	COG1802	Transcriptional regulator
RAM_27490	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RAM_27530	COG3483	tryptophan 2,3-dioxygenase activity
RAM_27545	COG2197	response regulator
RAM_27550	COG4585	Histidine kinase
RAM_27560	COG1131	(ABC) transporter
RAM_27570	COG3510	cephalosporin hydroxylase
RAM_27575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_27585	COG1819	glycosyl
RAM_27595	COG1819	glycosyl
RAM_27635	COG3629	intracellular signal transduction
RAM_27640	COG1819	glycosyl
RAM_27645	COG0574	Belongs to the PEP-utilizing enzyme family
RAM_27645	COG3848	Pyruvate phosphate dikinase
RAM_27660	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_27680	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_27690	COG2867	negative regulation of translational initiation
RAM_27695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_27700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RAM_27705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RAM_27710	COG0662	Cupin 2, conserved barrel domain protein
RAM_27725	COG3104	oligopeptide transport
RAM_27730	COG2345	Transcriptional regulator
RAM_27735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_27755	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_27800	COG3209	COG3209 Rhs family protein
RAM_27830	COG0659	secondary active sulfate transmembrane transporter activity
RAM_27845	COG0589	response to stress
RAM_27865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RAM_27880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RAM_27885	COG1042	CoA-binding domain protein
RAM_27885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_27885	COG0045	succinate-CoA ligase (ADP-forming) activity
RAM_27905	COG1271	oxidase subunit
RAM_27910	COG1294	oxidase, subunit
RAM_27915	COG4988	ABC transporter
RAM_27920	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
RAM_27930	COG2239	Acts as a magnesium transporter
RAM_27965	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_27990	COG4585	Histidine kinase
RAM_27995	COG2197	response regulator
RAM_28010	COG4585	Histidine kinase
RAM_28015	COG2197	response regulator
RAM_28070	COG2197	response regulator
RAM_28105	COG0681	Belongs to the peptidase S26 family
RAM_28110	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_28180	COG0405	Gamma-glutamyltransferase
RAM_28185	COG3706	GGDEF domain
RAM_28200	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_28235	COG1216	Glycosyl transferase, family 2
RAM_28240	COG1215	transferase activity, transferring glycosyl groups
RAM_28250	COG1132	(ABC) transporter
RAM_28270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_28275	COG0596	Alpha beta hydrolase
RAM_28330	COG2814	Major facilitator Superfamily
RAM_28345	COG3629	intracellular signal transduction
RAM_28345	COG3903	Transcriptional regulator
RAM_28430	COG0330	HflC and HflK could
RAM_28520	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_28590	COG0297	glycogen (starch) synthase activity
RAM_28595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_28630	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_28635	COG1309	transcriptional regulator
RAM_28640	COG4941	Belongs to the sigma-70 factor family
RAM_28645	COG4941	Belongs to the sigma-70 factor family
RAM_28650	COG4941	Belongs to the sigma-70 factor family
RAM_28655	COG3795	YCII-related domain
RAM_28675	COG3250	beta-galactosidase activity
RAM_28680	COG0583	DNA-binding transcription factor activity
RAM_28720	COG0515	serine threonine protein kinase
RAM_28725	COG1595	DNA-templated transcription, initiation
RAM_28730	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_28785	COG0596	Alpha beta hydrolase
RAM_28790	COG0596	Alpha beta hydrolase
RAM_28800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RAM_28815	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RAM_28815	COG1672	PFAM Archaeal ATPase
RAM_28820	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_28845	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_28875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RAM_28935	COG2205	protein histidine kinase activity
RAM_28940	COG0745	RESPONSE REGULATOR receiver
RAM_28945	COG1216	Glycosyl transferase, family 2
RAM_28950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RAM_28990	COG1309	transcriptional regulator
RAM_29045	COG4941	Belongs to the sigma-70 factor family
RAM_29065	COG1335	isochorismatase
RAM_29095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_29100	COG1309	transcriptional regulator
RAM_29115	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RAM_29120	COG1414	Transcriptional regulator
RAM_29125	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_29145	COG1278	Cold shock
RAM_29165	COG0300	oxidoreductase activity
RAM_29175	COG3795	YCII-related domain
RAM_29190	COG3263	regulation of cellular component size
RAM_29200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RAM_29210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RAM_29250	COG0745	RESPONSE REGULATOR receiver
RAM_29255	COG5002	protein histidine kinase activity
RAM_29255	COG5000	phosphorelay sensor kinase activity
RAM_29270	COG1733	regulation of RNA biosynthetic process
RAM_29280	COG1846	Transcriptional regulator
RAM_29285	COG0038	chloride channel
RAM_29320	COG3383	formate dehydrogenase (NAD+) activity
RAM_29320	COG0243	molybdopterin cofactor binding
RAM_29325	COG0243	molybdopterin cofactor binding
RAM_29325	COG3383	formate dehydrogenase (NAD+) activity
RAM_29330	COG0437	4 iron, 4 sulfur cluster binding
RAM_29365	COG2116	formate transmembrane transporter activity
RAM_29375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RAM_29395	COG0531	amino acid
RAM_29400	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_29435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RAM_29440	COG2080	2 iron, 2 sulfur cluster binding
RAM_29450	COG0667	Aldo Keto reductase
RAM_29460	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_29510	COG1609	Transcriptional regulator
RAM_29520	COG1609	Transcriptional regulator
RAM_29550	COG1609	Transcriptional regulator
RAM_29570	COG2207	Transcriptional regulator
RAM_29570	COG1917	Cupin 2, conserved barrel domain protein
RAM_29750	COG3293	Transposase
RAM_29780	COG1857	crispr-associated protein
RAM_29895	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_29895	COG4733	cellulase activity
RAM_29930	COG0154	amidase activity
RAM_29935	COG0789	Transcriptional regulator
RAM_29940	COG0640	Transcriptional regulator
RAM_29970	COG0673	inositol 2-dehydrogenase activity
RAM_29995	COG1653	transport
RAM_30025	COG3842	ATPase activity
RAM_30035	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RAM_30040	COG0028	Belongs to the TPP enzyme family
RAM_30060	COG2197	response regulator
RAM_30070	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RAM_30080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RAM_30090	COG0702	epimerase
RAM_30100	COG0583	DNA-binding transcription factor activity
RAM_30110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RAM_30175	COG0300	oxidoreductase activity
RAM_30180	COG4221	oxidoreductase activity
RAM_30185	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RAM_30190	COG0406	alpha-ribazole phosphatase activity
RAM_30190	COG0328	RNA-DNA hybrid ribonuclease activity
RAM_30245	COG2318	DinB family
RAM_30250	COG0667	Aldo Keto reductase
RAM_30265	COG2267	carboxylic ester hydrolase activity
RAM_30280	COG3903	Transcriptional regulator
RAM_30280	COG3629	intracellular signal transduction
RAM_30340	COG4974	Belongs to the 'phage' integrase family
RAM_30345	COG1012	belongs to the aldehyde dehydrogenase family
RAM_30395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RAM_30435	COG2815	serine threonine protein kinase
RAM_30435	COG0515	serine threonine protein kinase
RAM_30450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RAM_30480	COG3511	phospholipase C
RAM_30535	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_30585	COG0714	Associated with various cellular activities
RAM_30595	COG3552	Protein containing von Willebrand factor type A (VWA) domain
RAM_30600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RAM_30610	COG1733	regulation of RNA biosynthetic process
RAM_30620	COG5492	domain, Protein
RAM_30635	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_30640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RAM_30650	COG1414	Transcriptional regulator
RAM_30655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RAM_30670	COG0726	polysaccharide deacetylase
RAM_30755	COG1160	GTP binding
RAM_30785	COG0475	glutathione-regulated potassium exporter activity
RAM_30790	COG2936	dipeptidyl-peptidase activity
RAM_30795	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_30805	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RAM_30840	COG0504	CTP synthase activity
RAM_30850	COG1802	Transcriptional regulator
RAM_30855	COG1953	Uracil, thiamine, allantoin
RAM_30890	COG1063	alcohol dehydrogenase
RAM_30905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RAM_30920	COG0647	UMP catabolic process
RAM_30930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RAM_30935	COG2094	Belongs to the DNA glycosylase MPG family
RAM_30955	COG0165	Argininosuccinate lyase
RAM_30960	COG0137	argininosuccinate synthase activity
RAM_30965	COG1438	arginine binding
RAM_30970	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RAM_30975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RAM_30980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RAM_30985	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RAM_30990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RAM_31010	COG0596	Alpha beta hydrolase
RAM_31020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RAM_31020	COG0072	phenylalanine-tRNA ligase activity
RAM_31025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RAM_31035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RAM_31040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RAM_31045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RAM_31090	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RAM_31095	COG2610	gluconate transmembrane transporter activity
RAM_31130	COG4565	transcriptional regulatory protein
RAM_31135	COG3290	protein histidine kinase activity
RAM_31140	COG1301	dicarboxylic acid transport
RAM_31190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_31220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_31225	COG0328	RNA-DNA hybrid ribonuclease activity
RAM_31230	COG3012	SEC-C Motif Domain Protein
RAM_31240	COG3250	beta-galactosidase activity
RAM_31245	COG2272	Belongs to the type-B carboxylesterase lipase family
RAM_31260	COG0406	alpha-ribazole phosphatase activity
RAM_31280	COG1609	Transcriptional regulator
RAM_31305	COG1506	peptidase
RAM_31305	COG4946	Tricorn protease homolog
RAM_31305	COG0823	Involved in the tonB-independent uptake of proteins
RAM_31315	COG1131	(ABC) transporter
RAM_31335	COG1024	Enoyl-CoA hydratase
RAM_31380	COG0237	dephospho-CoA kinase activity
RAM_31380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RAM_31405	COG0539	negative regulation of cytoplasmic translation
RAM_31410	COG2226	methyltransferase
RAM_31430	COG1511	domain protein
RAM_31435	COG1309	transcriptional regulator
RAM_31440	COG2207	Transcriptional regulator
RAM_31445	COG0604	alcohol dehydrogenase
RAM_31470	COG0583	DNA-binding transcription factor activity
RAM_31485	COG0559	Belongs to the binding-protein-dependent transport system permease family
RAM_31685	COG0537	adenosine 5'-monophosphoramidase activity
RAM_31760	COG4585	Histidine kinase
RAM_31765	COG2197	response regulator
RAM_31785	COG2197	response regulator
RAM_31790	COG4585	Histidine kinase
RAM_31815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RAM_31820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RAM_31840	COG1454	alcohol dehydrogenase
RAM_31850	COG1012	belongs to the aldehyde dehydrogenase family
RAM_31870	COG0596	Alpha beta hydrolase
RAM_31890	COG4977	sequence-specific DNA binding
RAM_31895	COG0596	Alpha beta hydrolase
RAM_31905	COG0300	oxidoreductase activity
RAM_31945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_31990	COG3251	PFAM MbtH domain protein
RAM_32045	COG2814	Major facilitator Superfamily
RAM_32060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RAM_32065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RAM_32075	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RAM_32080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RAM_32100	COG0768	penicillin binding
RAM_32110	COG0275	rRNA processing
RAM_32115	COG2001	Belongs to the MraZ family
RAM_32145	COG0714	Associated with various cellular activities
RAM_32155	COG1305	Transglutaminase-like
RAM_32175	COG1192	Involved in chromosome partitioning
RAM_32180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RAM_32185	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RAM_32195	COG0167	dihydroorotate dehydrogenase activity
RAM_32215	COG1396	sequence-specific DNA binding
RAM_32220	COG1546	Belongs to the CinA family
RAM_32220	COG1058	Belongs to the CinA family
RAM_32230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RAM_32235	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RAM_32265	COG1674	ftsk spoiiie
RAM_32275	COG0655	NAD(P)H dehydrogenase (quinone) activity
RAM_32295	COG1113	amino acid transport
RAM_32305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RAM_32310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RAM_32350	COG3214	Protein conserved in bacteria
RAM_32390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RAM_32395	COG0612	Peptidase, M16
RAM_32400	COG1185	polyribonucleotide nucleotidyltransferase activity
RAM_32405	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RAM_32425	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RAM_32450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RAM_32460	COG2268	Band 7 protein
RAM_32475	COG2226	methyltransferase
RAM_32510	COG0195	Participates in both transcription termination and antitermination
RAM_32515	COG0779	Required for maturation of 30S ribosomal subunits
RAM_32545	COG3226	Transcriptional regulator
RAM_32555	COG4585	Histidine kinase
RAM_32560	COG2197	response regulator
RAM_32570	COG1733	regulation of RNA biosynthetic process
RAM_32580	COG1309	transcriptional regulator
RAM_32585	COG2936	dipeptidyl-peptidase activity
RAM_32600	COG0745	RESPONSE REGULATOR receiver
RAM_32605	COG5002	protein histidine kinase activity
RAM_32615	COG3629	intracellular signal transduction
RAM_32615	COG3903	Transcriptional regulator
RAM_32635	COG0583	DNA-binding transcription factor activity
RAM_32640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_32645	COG1024	Enoyl-CoA hydratase
RAM_32655	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_32660	COG1960	acyl-CoA dehydrogenase activity
RAM_32665	COG1316	TRANSCRIPTIONal
RAM_32695	COG0583	DNA-binding transcription factor activity
RAM_32715	COG2124	cytochrome p450
RAM_32755	COG3629	intracellular signal transduction
RAM_32755	COG3903	Transcriptional regulator
RAM_32810	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RAM_32850	COG1595	DNA-templated transcription, initiation
RAM_32880	COG3507	Belongs to the glycosyl hydrolase 43 family
RAM_32895	COG4941	Belongs to the sigma-70 factor family
RAM_32900	COG3795	YCII-related domain
RAM_32905	COG2267	carboxylic ester hydrolase activity
RAM_32910	COG1309	transcriptional regulator
RAM_32915	COG0604	alcohol dehydrogenase
RAM_32940	COG0443	Heat shock 70 kDa protein
RAM_32955	COG1228	amidohydrolase
RAM_33000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RAM_33030	COG2197	response regulator
RAM_33060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RAM_33060	COG2755	lipolytic protein G-D-S-L family
RAM_33105	COG3629	intracellular signal transduction
RAM_33105	COG3903	Transcriptional regulator
RAM_33135	COG0667	Aldo Keto reductase
RAM_33165	COG1960	acyl-CoA dehydrogenase activity
RAM_33180	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_33195	COG0596	Alpha beta hydrolase
RAM_33200	COG2197	response regulator
RAM_33225	COG0477	Major facilitator Superfamily
RAM_33280	COG4585	Histidine kinase
RAM_33285	COG2197	response regulator
RAM_33310	COG0586	Pfam SNARE associated Golgi protein
RAM_33320	COG1968	undecaprenyl-diphosphatase activity
RAM_33360	COG4585	Histidine kinase
RAM_33365	COG2197	response regulator
RAM_33375	COG2201	protein-glutamate methylesterase activity
RAM_33390	COG1309	transcriptional regulator
RAM_33395	COG0702	epimerase
RAM_33405	COG0702	epimerase
RAM_33430	COG2814	Major facilitator Superfamily
RAM_33455	COG4977	sequence-specific DNA binding
RAM_33510	COG1120	ATPase activity
RAM_33515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_33635	COG0243	molybdopterin cofactor binding
RAM_33685	COG0028	Belongs to the TPP enzyme family
RAM_33690	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_33695	COG0247	lactate metabolic process
RAM_33695	COG0277	FAD linked oxidase domain protein
RAM_33725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RAM_33730	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
RAM_33740	COG1659	Linocin_M18 bacteriocin protein
RAM_33765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RAM_33785	COG4106	trans-aconitate 2-methyltransferase activity
RAM_33800	COG1595	DNA-templated transcription, initiation
RAM_33815	COG0477	Major facilitator Superfamily
RAM_33835	COG2318	DinB family
RAM_33855	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RAM_33865	COG2197	response regulator
RAM_33870	COG4585	Histidine kinase
RAM_33880	COG1131	(ABC) transporter
RAM_33885	COG0423	glycine-tRNA ligase activity
RAM_33925	COG0701	Predicted permease
RAM_33935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RAM_33940	COG1381	Involved in DNA repair and RecF pathway recombination
RAM_33970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RAM_33985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RAM_34000	COG0537	adenosine 5'-monophosphoramidase activity
RAM_34010	COG0484	heat shock protein binding
RAM_34015	COG1420	regulation of RNA biosynthetic process
RAM_34040	COG0667	Aldo Keto reductase
RAM_34075	COG2205	protein histidine kinase activity
RAM_34080	COG0745	RESPONSE REGULATOR receiver
RAM_34085	COG1953	Uracil, thiamine, allantoin
RAM_34095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RAM_34185	COG0326	Molecular chaperone. Has ATPase activity
RAM_34200	COG1024	Enoyl-CoA hydratase
RAM_34205	COG2732	(Barnase) inhibitor
RAM_34210	COG4290	ribonuclease
RAM_34220	COG0604	alcohol dehydrogenase
RAM_34230	COG0531	amino acid
RAM_34235	COG2070	2-Nitropropane dioxygenase
RAM_34295	COG0268	Binds directly to 16S ribosomal RNA
RAM_34305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RAM_34315	COG2333	competence protein COMEC
RAM_34315	COG0658	competence protein
RAM_34325	COG1307	EDD domain protein, DegV family
RAM_34335	COG0406	alpha-ribazole phosphatase activity
RAM_34340	COG0799	negative regulation of ribosome biogenesis
RAM_34345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RAM_34355	COG0477	Major facilitator Superfamily
RAM_34360	COG0018	arginyl-trna synthetase
RAM_34380	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_34390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RAM_34395	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RAM_34400	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RAM_34405	COG1530	ribonuclease E activity
RAM_34405	COG1530	ribonuclease E activity
RAM_34425	COG1131	(ABC) transporter
RAM_34440	COG0105	UTP biosynthetic process
RAM_34450	COG2366	antibiotic biosynthetic process
RAM_34460	COG0285	dihydrofolate synthase activity
RAM_34485	COG0583	DNA-binding transcription factor activity
RAM_34490	COG0525	valine-tRNA ligase activity
RAM_34500	COG1846	Transcriptional regulator
RAM_34505	COG0477	Major facilitator Superfamily
RAM_34520	COG1316	TRANSCRIPTIONal
RAM_34540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RAM_34575	COG0740	serine-type endopeptidase activity
RAM_34580	COG0740	serine-type endopeptidase activity
RAM_34585	COG0544	peptidyl-prolyl cis-trans isomerase activity
RAM_34595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RAM_34605	COG2205	protein histidine kinase activity
RAM_34610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RAM_34670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RAM_34710	COG3903	Transcriptional regulator
RAM_34710	COG3629	intracellular signal transduction
RAM_34720	COG3537	Alpha-1,2-mannosidase
RAM_34725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RAM_34730	COG3559	Exporter of polyketide antibiotics
RAM_34735	COG1131	(ABC) transporter
RAM_34740	COG1309	transcriptional regulator
RAM_34750	COG1940	carbohydrate kinase activity
RAM_34770	COG2814	Major facilitator Superfamily
RAM_34810	COG0693	protein deglycase activity
RAM_34815	COG2208	phosphoserine phosphatase activity
RAM_34820	COG0784	Response regulator, receiver
RAM_34820	COG5002	protein histidine kinase activity
RAM_34835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RAM_34875	COG0583	DNA-binding transcription factor activity
RAM_34885	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_34895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_34910	COG1733	regulation of RNA biosynthetic process
RAM_34915	COG3345	alpha-galactosidase
RAM_34940	COG0459	protein refolding
RAM_34950	COG0698	ribose 5-phosphate isomerase
RAM_34970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RAM_34985	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RAM_35005	COG0668	transmembrane transport
RAM_35015	COG0366	Alpha amylase catalytic
RAM_35035	COG2902	Dehydrogenase
RAM_35050	COG3336	cytochrome c oxidase
RAM_35065	COG0738	Major facilitator superfamily
RAM_35080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_35085	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RAM_35105	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RAM_35145	COG0477	Major facilitator Superfamily
RAM_35150	COG0596	Alpha beta hydrolase
RAM_35170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_35195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_35245	COG2124	cytochrome p450
RAM_35280	COG1733	regulation of RNA biosynthetic process
RAM_35285	COG4941	Belongs to the sigma-70 factor family
RAM_35290	COG3795	YCII-related domain
RAM_35300	COG0009	L-threonylcarbamoyladenylate synthase
RAM_35315	COG2197	response regulator
RAM_35325	COG4977	sequence-specific DNA binding
RAM_35325	COG1917	Cupin 2, conserved barrel domain protein
RAM_35330	COG2197	response regulator
RAM_35335	COG4585	Histidine kinase
RAM_35350	COG1733	regulation of RNA biosynthetic process
RAM_35380	COG1937	Protein conserved in bacteria
RAM_35405	COG4221	oxidoreductase activity
RAM_35420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RAM_35465	COG0745	RESPONSE REGULATOR receiver
RAM_35470	COG2205	protein histidine kinase activity
RAM_35485	COG1609	Transcriptional regulator
RAM_35520	COG0367	asparagine synthase
RAM_35530	COG1940	carbohydrate kinase activity
RAM_35550	COG0583	DNA-binding transcription factor activity
RAM_35590	COG1609	Transcriptional regulator
RAM_35625	COG0531	amino acid
RAM_35630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RAM_35660	COG3835	regulator
RAM_35685	COG1021	2,3-dihydroxybenzoate-AMP ligase
RAM_35695	COG1733	regulation of RNA biosynthetic process
RAM_35705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_35710	COG0583	DNA-binding transcription factor activity
RAM_35755	COG1024	Enoyl-CoA hydratase
RAM_35815	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_35830	COG1643	Atp-dependent helicase
RAM_35845	COG3268	Saccharopine dehydrogenase
RAM_35850	COG2072	flavoprotein involved in K transport
RAM_35865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RAM_35865	COG1796	DNA polymerase
RAM_35875	COG1802	Transcriptional regulator
RAM_35900	COG3706	GGDEF domain
RAM_35910	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
RAM_35930	COG4941	Belongs to the sigma-70 factor family
RAM_35950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RAM_35965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_35975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RAM_35980	COG2318	DinB family
RAM_35985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_35995	COG0235	Class ii aldolase
RAM_35995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RAM_36015	COG1695	Transcriptional regulator
RAM_36025	COG3959	Transketolase, thiamine diphosphate binding domain
RAM_36030	COG1309	transcriptional regulator
RAM_36035	COG0247	lactate metabolic process
RAM_36035	COG0277	FAD linked oxidase domain protein
RAM_36045	COG2197	response regulator
RAM_36055	COG0410	ABC transporter
RAM_36065	COG0559	Belongs to the binding-protein-dependent transport system permease family
RAM_36070	COG0559	Belongs to the binding-protein-dependent transport system permease family
RAM_36085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_36090	COG3537	Alpha-1,2-mannosidase
RAM_36095	COG1739	Uncharacterized protein family UPF0029
RAM_36100	COG0067	glutamate synthase
RAM_36100	COG0069	glutamate synthase activity
RAM_36100	COG0070	glutamate synthase
RAM_36110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RAM_36145	COG1492	cobalamin metabolic process
RAM_36150	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RAM_36160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RAM_36165	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RAM_36170	COG2378	regulation of single-species biofilm formation
RAM_36185	COG1797	cobyrinic acid a,c-diamide synthase activity
RAM_36220	COG0778	Nitroreductase
RAM_36250	COG1131	(ABC) transporter
RAM_36260	COG1476	TRANSCRIPTIONal
RAM_36275	COG3469	chitinase activity
RAM_36295	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RAM_36320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_36330	COG0433	COG0433 Predicted ATPase
RAM_36335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RAM_36340	COG0477	Major facilitator Superfamily
RAM_36555	COG0535	radical SAM domain protein
RAM_36560	COG1960	acyl-CoA dehydrogenase activity
RAM_36570	COG0022	dehydrogenase e1 component
RAM_36575	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_36580	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_36585	COG1024	Enoyl-CoA hydratase
RAM_36605	COG0477	Major facilitator Superfamily
RAM_36635	COG2186	Transcriptional regulator
RAM_36640	COG1012	belongs to the aldehyde dehydrogenase family
RAM_36645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_36660	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_36695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RAM_36705	COG1309	transcriptional regulator
RAM_36720	COG0604	alcohol dehydrogenase
RAM_36770	COG1960	acyl-CoA dehydrogenase activity
RAM_36775	COG1960	acyl-CoA dehydrogenase activity
RAM_36785	COG2186	Transcriptional regulator
RAM_36800	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_36800	COG3321	synthase
RAM_36800	COG0604	alcohol dehydrogenase
RAM_36805	COG1960	acyl-CoA dehydrogenase activity
RAM_36810	COG1960	acyl-CoA dehydrogenase activity
RAM_36825	COG1024	Enoyl-CoA hydratase
RAM_36850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_36865	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_36895	COG1414	Transcriptional regulator
RAM_36905	COG2267	carboxylic ester hydrolase activity
RAM_36920	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_36925	COG0259	pyridoxamine-phosphate oxidase activity
RAM_36930	COG0183	Belongs to the thiolase family
RAM_36940	COG1024	Enoyl-CoA hydratase
RAM_36945	COG1960	acyl-CoA dehydrogenase activity
RAM_36970	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_36980	COG1024	Enoyl-CoA hydratase
RAM_36990	COG1024	Enoyl-CoA hydratase
RAM_37010	COG1024	Enoyl-CoA hydratase
RAM_37020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RAM_37030	COG1012	belongs to the aldehyde dehydrogenase family
RAM_37050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RAM_37085	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_37100	COG1309	transcriptional regulator
RAM_37145	COG1063	alcohol dehydrogenase
RAM_37155	COG4585	Histidine kinase
RAM_37160	COG2197	response regulator
RAM_37180	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_37185	COG2271	Major facilitator Superfamily
RAM_37220	COG0235	Class ii aldolase
RAM_37225	COG0477	Major facilitator Superfamily
RAM_37230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_37260	COG0673	inositol 2-dehydrogenase activity
RAM_37265	COG2211	Major facilitator Superfamily
RAM_37270	COG1609	Transcriptional regulator
RAM_37280	COG1653	transport
RAM_37290	COG0395	ABC-type sugar transport system, permease component
RAM_37300	COG0596	Alpha beta hydrolase
RAM_37310	COG0596	Alpha beta hydrolase
RAM_37325	COG2084	Dehydrogenase
RAM_37335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RAM_37340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RAM_37350	COG0189	ligase activity
RAM_37365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_37370	COG0625	glutathione transferase activity
RAM_37380	COG2271	Major facilitator Superfamily
RAM_37385	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RAM_37395	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_37585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RAM_37635	COG2856	Zn peptidase
RAM_37670	COG0702	epimerase
RAM_37700	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RAM_37705	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RAM_37710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_37715	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_37720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RAM_37720	COG2169	Transcriptional regulator
RAM_37790	COG4733	cellulase activity
RAM_37790	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_37820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RAM_37855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RAM_37860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RAM_37880	COG1960	acyl-CoA dehydrogenase activity
RAM_37905	COG0154	amidase activity
RAM_37920	COG0583	DNA-binding transcription factor activity
RAM_37960	COG1131	(ABC) transporter
RAM_37970	COG3345	alpha-galactosidase
RAM_38015	COG0438	transferase activity, transferring glycosyl groups
RAM_38035	COG0297	glycogen (starch) synthase activity
RAM_38040	COG0438	transferase activity, transferring glycosyl groups
RAM_38055	COG0463	Glycosyl transferase, family 2
RAM_38090	COG3250	beta-galactosidase activity
RAM_38095	COG3401	FG-GAP repeat protein
RAM_38125	COG0395	ABC-type sugar transport system, permease component
RAM_38130	COG1175	transmembrane transport
RAM_38170	COG0596	Alpha beta hydrolase
RAM_38175	COG2208	phosphoserine phosphatase activity
RAM_38175	COG2770	Histidine kinase
RAM_38185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RAM_38195	COG2226	methyltransferase
RAM_38205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RAM_38245	COG0667	Aldo Keto reductase
RAM_38250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_38270	COG0587	DNA-directed DNA polymerase activity
RAM_38275	COG4941	Belongs to the sigma-70 factor family
RAM_38280	COG3795	YCII-related domain
RAM_38290	COG1982	Orn Lys Arg decarboxylase major
RAM_38305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_38315	COG1725	Transcriptional regulator
RAM_38320	COG1131	(ABC) transporter
RAM_38340	COG3509	depolymerase
RAM_38355	COG1528	Iron-storage protein
RAM_38380	COG2018	Roadblock/LC7 domain
RAM_38405	COG1764	response to oxidative stress
RAM_38415	COG2267	carboxylic ester hydrolase activity
RAM_38430	COG0667	Aldo Keto reductase
RAM_38435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RAM_38475	COG0395	ABC-type sugar transport system, permease component
RAM_38480	COG1175	transmembrane transport
RAM_38485	COG1609	Transcriptional regulator
RAM_38510	COG0604	alcohol dehydrogenase
RAM_38540	COG1595	DNA-templated transcription, initiation
RAM_38550	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_38555	COG0129	dihydroxy-acid dehydratase activity
RAM_38560	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RAM_38620	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RAM_38655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_38665	COG2226	methyltransferase
RAM_38670	COG2508	Transcriptional regulator
RAM_38680	COG3655	Transcriptional regulator
RAM_38725	COG4981	capsule polysaccharide biosynthetic process
RAM_38750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_38755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RAM_38815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RAM_38830	COG3226	Transcriptional regulator
RAM_38890	COG0508	dehydrogenase complex catalyzes the overall conversion of
RAM_38915	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_38930	COG0745	RESPONSE REGULATOR receiver
RAM_38935	COG5002	protein histidine kinase activity
RAM_38965	COG2815	serine threonine protein kinase
RAM_38965	COG0515	serine threonine protein kinase
RAM_38985	COG0640	Transcriptional regulator
RAM_38995	COG2837	iron assimilation
RAM_39000	COG3511	phospholipase C
RAM_39015	COG0784	Response regulator, receiver
RAM_39020	COG4251	negative regulation of phosphorylation
RAM_39025	COG0745	RESPONSE REGULATOR receiver
RAM_39120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RAM_39145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_39225	COG1309	transcriptional regulator
RAM_39255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RAM_39260	COG1309	transcriptional regulator
RAM_39280	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_39285	COG3383	formate dehydrogenase (NAD+) activity
RAM_39290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_39300	COG1733	regulation of RNA biosynthetic process
RAM_39335	COG2814	Major facilitator Superfamily
RAM_39405	COG0706	membrane insertase activity
RAM_39415	COG1408	metallophosphoesterase
RAM_39425	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RAM_39430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RAM_39455	COG2018	Roadblock/LC7 domain
RAM_39475	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_39485	COG3706	GGDEF domain
RAM_39500	COG1316	TRANSCRIPTIONal
RAM_39535	COG4977	sequence-specific DNA binding
RAM_39540	COG0667	Aldo Keto reductase
RAM_39545	COG2207	Transcriptional regulator
RAM_39575	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RAM_39580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RAM_39585	COG1234	tRNA 3'-trailer cleavage
RAM_39590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RAM_39605	COG1794	racemase activity, acting on amino acids and derivatives
RAM_39610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_39640	COG3191	aminopeptidase activity
RAM_39655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RAM_39660	COG1335	isochorismatase
RAM_39665	COG0800	Aldolase
RAM_39675	COG1268	BioY protein
RAM_39705	COG3830	Belongs to the UPF0237 family
RAM_39705	COG0560	Phosphoserine phosphatase
RAM_39710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RAM_39720	COG2267	carboxylic ester hydrolase activity
RAM_39740	COG2801	Transposase and inactivated derivatives
RAM_39755	COG0626	cystathionine gamma-synthase activity
RAM_39760	COG1522	sequence-specific DNA binding
RAM_39770	COG1522	sequence-specific DNA binding
RAM_39805	COG2376	Dihydroxyacetone kinase
RAM_39835	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
RAM_39840	COG1051	belongs to the nudix hydrolase family
RAM_39855	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RAM_39860	COG4977	sequence-specific DNA binding
RAM_39865	COG1335	isochorismatase
RAM_39885	COG1280	lysine exporter protein (LysE YggA)
RAM_39890	COG1280	lysine exporter protein (LysE YggA)
RAM_39900	COG0702	epimerase
RAM_39905	COG3631	Ketosteroid isomerase-related protein
RAM_39910	COG1309	transcriptional regulator
RAM_39925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RAM_39935	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RAM_39940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RAM_39945	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RAM_39950	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RAM_39955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RAM_39960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RAM_39965	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RAM_39970	COG0356	it plays a direct role in the translocation of protons across the membrane
RAM_39980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RAM_39995	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_40000	COG0463	Glycosyl transferase, family 2
RAM_40020	COG0254	rRNA binding
RAM_40030	COG0083	homoserine kinase activity
RAM_40035	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RAM_40040	COG0460	homoserine dehydrogenase
RAM_40045	COG0019	diaminopimelate decarboxylase activity
RAM_40050	COG0018	arginyl-trna synthetase
RAM_40085	COG0596	Alpha beta hydrolase
RAM_40170	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RAM_40185	COG3629	intracellular signal transduction
RAM_40185	COG3903	Transcriptional regulator
RAM_40190	COG2124	cytochrome p450
RAM_40190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RAM_40210	COG3345	alpha-galactosidase
RAM_40215	COG3693	PFAM glycoside hydrolase, family 10
RAM_40235	COG3693	PFAM glycoside hydrolase, family 10
RAM_40305	COG5433	transposase activity
RAM_40360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_40365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_40385	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_40395	COG0145	ligase activity
RAM_40415	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
RAM_40430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RAM_40445	COG0154	amidase activity
RAM_40475	COG0473	3-isopropylmalate dehydrogenase activity
RAM_40495	COG0667	Aldo Keto reductase
RAM_40515	COG0028	Belongs to the TPP enzyme family
RAM_40540	COG4585	Histidine kinase
RAM_40545	COG2197	response regulator
RAM_40550	COG2409	Drug exporters of the RND superfamily
RAM_40555	COG3537	Alpha-1,2-mannosidase
RAM_40560	COG1024	Enoyl-CoA hydratase
RAM_40560	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_40565	COG0183	Belongs to the thiolase family
RAM_40570	COG1309	transcriptional regulator
RAM_40610	COG1960	acyl-CoA dehydrogenase activity
RAM_40615	COG1960	acyl-CoA dehydrogenase activity
RAM_40680	COG4221	oxidoreductase activity
RAM_40710	COG1960	acyl-CoA dehydrogenase activity
RAM_40720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_40750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RAM_40765	COG0346	lactoylglutathione lyase activity
RAM_40785	COG2226	methyltransferase
RAM_40790	COG2508	Transcriptional regulator
RAM_40790	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RAM_40805	COG0686	Belongs to the AlaDH PNT family
RAM_40815	COG2205	protein histidine kinase activity
RAM_40825	COG0745	RESPONSE REGULATOR receiver
RAM_40840	COG1132	(ABC) transporter
RAM_40855	COG0567	Dehydrogenase, E1 component
RAM_40855	COG0508	dehydrogenase complex catalyzes the overall conversion of
RAM_40865	COG1216	Glycosyl transferase, family 2
RAM_40870	COG2223	nitrite transmembrane transporter activity
RAM_40880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_40895	COG1174	glycine betaine transport
RAM_40900	COG1174	glycine betaine transport
RAM_40905	COG1125	glycine betaine transport
RAM_40905	COG0517	IMP dehydrogenase activity
RAM_40920	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RAM_40930	COG1846	Transcriptional regulator
RAM_40945	COG0406	alpha-ribazole phosphatase activity
RAM_40960	COG1597	lipid kinase activity
RAM_40980	COG1595	DNA-templated transcription, initiation
RAM_40985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RAM_40995	COG2135	peptidase activity
RAM_41025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RAM_41030	COG1011	Hydrolase
RAM_41045	COG0653	protein targeting
RAM_41050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RAM_41060	COG5401	PFAM Sporulation and spore germination
RAM_41065	COG5000	phosphorelay sensor kinase activity
RAM_41065	COG5002	protein histidine kinase activity
RAM_41070	COG0745	RESPONSE REGULATOR receiver
RAM_41080	COG1414	Transcriptional regulator
RAM_41150	COG0531	amino acid
RAM_41160	COG3903	Transcriptional regulator
RAM_41160	COG3629	intracellular signal transduction
RAM_41165	COG1482	cell wall glycoprotein biosynthetic process
RAM_41175	COG2835	tetraacyldisaccharide 4'-kinase activity
RAM_41180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RAM_41220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_41235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RAM_41240	COG0601	transmembrane transport
RAM_41250	COG0747	negative chemotaxis
RAM_41270	COG0180	Tryptophanyl-tRNA synthetase
RAM_41280	COG2205	protein histidine kinase activity
RAM_41285	COG0745	RESPONSE REGULATOR receiver
RAM_41295	COG1131	(ABC) transporter
RAM_41305	COG3842	ATPase activity
RAM_41310	COG4149	molybdate abc transporter
RAM_41320	COG2154	pterin-4-alpha-carbinolamine dehydratase
RAM_41350	COG0012	GTP binding
RAM_41365	COG0419	ATPase involved in DNA repair
RAM_41370	COG0420	3'-5' exonuclease activity
RAM_41385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RAM_41395	COG1570	exodeoxyribonuclease VII activity
RAM_41405	COG1722	exodeoxyribonuclease VII activity
RAM_41420	COG0492	ferredoxin-NADP+ reductase activity
RAM_41425	COG0114	fumarate hydratase activity
RAM_41435	COG1793	dna ligase
RAM_41450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_41475	COG1228	amidohydrolase
RAM_41480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RAM_41505	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
RAM_41535	COG1331	Highly conserved protein containing a thioredoxin domain
RAM_41550	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_41555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RAM_41565	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_41575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RAM_41580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_41590	COG3185	4-Hydroxyphenylpyruvate dioxygenase
RAM_41620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RAM_41655	COG0183	Belongs to the thiolase family
RAM_41715	COG3629	intracellular signal transduction
RAM_41715	COG3903	Transcriptional regulator
RAM_41720	COG2723	6-phospho-beta-galactosidase activity
RAM_41730	COG1175	transmembrane transport
RAM_41745	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_41750	COG0667	Aldo Keto reductase
RAM_41760	COG0477	Major facilitator Superfamily
RAM_41795	COG2207	Transcriptional regulator
RAM_41810	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_41825	COG2205	protein histidine kinase activity
RAM_41830	COG0148	phosphopyruvate hydratase activity
RAM_41840	COG1132	(ABC) transporter
RAM_41940	COG1595	DNA-templated transcription, initiation
RAM_41945	COG0515	serine threonine protein kinase
RAM_41945	COG2815	serine threonine protein kinase
RAM_41980	COG1191	sigma factor activity
RAM_42050	COG1515	deoxyribonuclease V activity
RAM_42065	COG4608	Belongs to the ABC transporter superfamily
RAM_42070	COG0444	Belongs to the ABC transporter superfamily
RAM_42110	COG0148	phosphopyruvate hydratase activity
RAM_42135	COG0672	)-iron permease
RAM_42140	COG2822	iron ion transport
RAM_42145	COG2837	iron assimilation
RAM_42175	COG1131	(ABC) transporter
RAM_42225	COG0586	Pfam SNARE associated Golgi protein
RAM_42235	COG4585	Histidine kinase
RAM_42240	COG2197	response regulator
RAM_42245	COG2133	pyrroloquinoline quinone binding
RAM_42270	COG1051	belongs to the nudix hydrolase family
RAM_42275	COG1309	transcriptional regulator
RAM_42290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RAM_42320	COG0193	aminoacyl-tRNA hydrolase activity
RAM_42335	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_42340	COG0488	(ABC) transporter
RAM_42350	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RAM_42355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RAM_42360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RAM_42365	COG3583	domain protein
RAM_42370	COG0084	hydrolase, TatD family'
RAM_42375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RAM_42430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RAM_42435	COG0515	serine threonine protein kinase
RAM_42435	COG2815	serine threonine protein kinase
RAM_42455	COG2258	MOSC domain
RAM_42470	COG1595	DNA-templated transcription, initiation
RAM_42515	COG5001	Diguanylate cyclase
RAM_42520	COG2124	cytochrome p450
RAM_42525	COG1192	Involved in chromosome partitioning
RAM_42550	COG0745	RESPONSE REGULATOR receiver
RAM_42555	COG2205	protein histidine kinase activity
RAM_42560	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RAM_42565	COG1181	Belongs to the D-alanine--D-alanine ligase family
RAM_42575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_42580	COG1733	regulation of RNA biosynthetic process
RAM_42585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RAM_42590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_42590	COG2226	methyltransferase
RAM_42590	COG3433	isochorismatase activity
RAM_42605	COG1280	lysine exporter protein (LysE YggA)
RAM_42615	COG0515	serine threonine protein kinase
RAM_42675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_42685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RAM_42690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RAM_42715	COG0315	cyclic pyranopterin monophosphate synthase activity
RAM_42715	COG0521	Mo-molybdopterin cofactor biosynthetic process
RAM_42735	COG5002	protein histidine kinase activity
RAM_42740	COG0745	RESPONSE REGULATOR receiver
RAM_42760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RAM_42785	COG1349	DNA-binding transcription factor activity
RAM_42800	COG2860	membrane
RAM_42805	COG2197	response regulator
RAM_42810	COG2264	protein methyltransferase activity
RAM_42820	COG0477	Major facilitator Superfamily
RAM_42830	COG0667	Aldo Keto reductase
RAM_42835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_42850	COG2815	serine threonine protein kinase
RAM_42850	COG0515	serine threonine protein kinase
RAM_42855	COG0483	inositol monophosphate 1-phosphatase activity
RAM_42865	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_42880	COG0297	glycogen (starch) synthase activity
RAM_42900	COG3285	dna ligase
RAM_42900	COG1793	dna ligase
RAM_42910	COG0583	DNA-binding transcription factor activity
RAM_42920	COG2755	lipolytic protein G-D-S-L family
RAM_42920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RAM_42980	COG0444	Belongs to the ABC transporter superfamily
RAM_42985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RAM_42990	COG0601	transmembrane transport
RAM_43000	COG0747	negative chemotaxis
RAM_43030	COG3469	chitinase activity
RAM_43045	COG4336	lyase activity
RAM_43050	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RAM_43055	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RAM_43060	COG1984	allophanate hydrolase subunit 2
RAM_43100	COG1321	iron dependent repressor
RAM_43120	COG1024	Enoyl-CoA hydratase
RAM_43125	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_43150	COG1169	isochorismate synthase
RAM_43165	COG2182	Extracellular solute-binding protein
RAM_43170	COG1175	transmembrane transport
RAM_43175	COG0395	ABC-type sugar transport system, permease component
RAM_43200	COG1595	DNA-templated transcription, initiation
RAM_43215	COG0277	FAD linked oxidase domain protein
RAM_43240	COG4152	abc transporter atp-binding protein
RAM_43255	COG0415	Belongs to the DNA photolyase family
RAM_43275	COG1960	acyl-CoA dehydrogenase activity
RAM_43300	COG2017	converts alpha-aldose to the beta-anomer
RAM_43310	COG1309	transcriptional regulator
RAM_43335	COG0259	pyridoxamine-phosphate oxidase activity
RAM_43355	COG0829	nickel cation binding
RAM_43360	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RAM_43370	COG0804	urea catabolic process
RAM_43375	COG0832	Belongs to the urease beta subunit family
RAM_43380	COG0831	urea catabolic process
RAM_43415	COG2197	response regulator
RAM_43420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RAM_43435	COG5650	phosphatidylinositol metabolic process
RAM_43440	COG1228	amidohydrolase
RAM_43445	COG0577	efflux transmembrane transporter activity
RAM_43445	COG1136	(ABC) transporter
RAM_43450	COG0577	efflux transmembrane transporter activity
RAM_43450	COG1136	(ABC) transporter
RAM_43465	COG0745	RESPONSE REGULATOR receiver
RAM_43470	COG2205	protein histidine kinase activity
RAM_43495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RAM_43520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RAM_43525	COG2814	Major facilitator Superfamily
RAM_43540	COG2252	PERMEase
RAM_43565	COG2814	Major facilitator Superfamily
RAM_43575	COG1278	Cold shock
RAM_43595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RAM_43600	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_43610	COG1595	DNA-templated transcription, initiation
RAM_43620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_43660	COG0384	phenazine biosynthesis protein PhzF
RAM_43665	COG3304	Inner membrane component domain
RAM_43670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RAM_43705	COG1846	Transcriptional regulator
RAM_43710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RAM_43720	COG1388	LysM domain
RAM_43770	COG2018	Roadblock/LC7 domain
RAM_43785	COG2018	Roadblock/LC7 domain
RAM_43790	COG0642	Histidine kinase
RAM_43795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RAM_43800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_43805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_43810	COG1116	anion transmembrane transporter activity
RAM_43850	COG3142	Participates in the control of copper homeostasis
RAM_43870	COG1061	Type III restriction enzyme res subunit
RAM_43890	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_43905	COG0459	protein refolding
RAM_43915	COG1278	Cold shock
RAM_43945	COG2261	transglycosylase associated protein
RAM_43955	COG0688	phosphatidylethanolamine metabolic process
RAM_43965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_43980	COG0242	peptide deformylase activity
RAM_43990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_43995	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RAM_44000	COG0351	phosphomethylpyrimidine kinase
RAM_44020	COG2022	thiamine diphosphate biosynthetic process
RAM_44035	COG0352	thiamine-phosphate diphosphorylase activity
RAM_44045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RAM_44050	COG0477	Major facilitator Superfamily
RAM_44060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RAM_44065	COG2971	BadF BadG BcrA BcrD
RAM_44075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RAM_44105	COG3629	intracellular signal transduction
RAM_44105	COG3903	Transcriptional regulator
RAM_44110	COG5285	phytanoyl-CoA dioxygenase
RAM_44115	COG1917	Cupin 2, conserved barrel domain protein
RAM_44130	COG1752	Esterase of the alpha-beta hydrolase superfamily
RAM_44140	COG1733	regulation of RNA biosynthetic process
RAM_44145	COG4399	Belongs to the UPF0754 family
RAM_44160	COG5416	Lipopolysaccharide assembly protein A domain
RAM_44220	COG1733	regulation of RNA biosynthetic process
RAM_44260	COG0346	lactoylglutathione lyase activity
RAM_44270	COG1832	CoA-binding protein
RAM_44315	COG0745	RESPONSE REGULATOR receiver
RAM_44320	COG2205	protein histidine kinase activity
RAM_44325	COG1492	cobalamin metabolic process
RAM_44330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RAM_44340	COG1309	transcriptional regulator
RAM_44350	COG1620	l-lactate permease
RAM_44360	COG4941	Belongs to the sigma-70 factor family
RAM_44365	COG3795	YCII-related domain
RAM_44370	COG3795	YCII-related domain
RAM_44390	COG2205	protein histidine kinase activity
RAM_44430	COG1595	DNA-templated transcription, initiation
RAM_44470	COG0789	Transcriptional regulator
RAM_44490	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RAM_44525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RAM_44535	COG1329	Transcriptional regulator
RAM_44540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RAM_44545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RAM_44565	COG0215	cysteine-tRNA ligase activity
RAM_44605	COG0235	Class ii aldolase
RAM_44620	COG4399	Belongs to the UPF0754 family
RAM_44625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RAM_44630	COG1121	(ABC) transporter
RAM_44635	COG0803	Belongs to the bacterial solute-binding protein 9 family
RAM_44640	COG1609	Transcriptional regulator
RAM_44675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_44685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RAM_44760	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
RAM_44775	COG1396	sequence-specific DNA binding
RAM_44780	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
RAM_44785	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
RAM_44815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RAM_44825	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RAM_44830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RAM_44835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RAM_44860	COG0789	Transcriptional regulator
RAM_44875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RAM_44880	COG0302	gtp cyclohydrolase
RAM_44885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_44915	COG0037	tRNA processing
RAM_44930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RAM_44940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RAM_44945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RAM_45035	COG2188	Transcriptional regulator
RAM_45050	COG1674	ftsk spoiiie
RAM_45090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RAM_45095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RAM_45125	COG1754	DNA topoisomerase type I activity
RAM_45125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RAM_45145	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RAM_45150	COG1205	dead DEAH box helicase
RAM_45150	COG1111	helicase
RAM_45195	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_45200	COG3876	Protein conserved in bacteria
RAM_45205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RAM_45210	COG1737	Transcriptional regulator
RAM_45215	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RAM_45220	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RAM_45230	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
RAM_45240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_45260	COG3104	oligopeptide transport
RAM_45265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RAM_45275	COG0596	Alpha beta hydrolase
RAM_45365	COG2272	Belongs to the type-B carboxylesterase lipase family
RAM_45375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_45415	COG2894	cell division
RAM_45425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RAM_45435	COG1408	metallophosphoesterase
RAM_45440	COG2226	methyltransferase
RAM_45475	COG0463	Glycosyl transferase, family 2
RAM_45480	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RAM_45490	COG2192	nodulation
RAM_45505	COG0076	glutamate decarboxylase activity
RAM_45510	COG0783	Belongs to the Dps family
RAM_45515	COG1764	response to oxidative stress
RAM_45540	COG2814	Major facilitator Superfamily
RAM_45555	COG1690	Belongs to the RtcB family
RAM_45590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RAM_45620	COG0583	DNA-binding transcription factor activity
RAM_45625	COG0697	spore germination
RAM_45640	COG3795	YCII-related domain
RAM_45645	COG4941	Belongs to the sigma-70 factor family
RAM_45650	COG4608	Belongs to the ABC transporter superfamily
RAM_45670	COG0747	negative chemotaxis
RAM_45680	COG1216	Glycosyl transferase, family 2
RAM_45700	COG1215	transferase activity, transferring glycosyl groups
RAM_45710	COG1705	Flagellar rod assembly protein muramidase FlgJ
RAM_45715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RAM_45720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RAM_45730	COG1733	regulation of RNA biosynthetic process
RAM_45735	COG3467	pyridoxamine 5'-phosphate
RAM_45740	COG2801	Transposase and inactivated derivatives
RAM_45785	COG1116	anion transmembrane transporter activity
RAM_45790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_45800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RAM_45805	COG2205	protein histidine kinase activity
RAM_45810	COG0745	RESPONSE REGULATOR receiver
RAM_45825	COG2197	response regulator
RAM_45845	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_45850	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RAM_45850	COG5479	isomerase activity
RAM_45890	COG1674	ftsk spoiiie
RAM_45935	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
RAM_45940	COG2175	clavaminate synthase activity
RAM_45995	COG4702	Belongs to the UPF0303 family
RAM_46005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RAM_46010	COG0789	Transcriptional regulator
RAM_46015	COG0395	ABC-type sugar transport system, permease component
RAM_46020	COG1175	transmembrane transport
RAM_46035	COG1802	Transcriptional regulator
RAM_46065	COG3973	AAA domain
RAM_46095	COG0673	inositol 2-dehydrogenase activity
RAM_46110	COG3345	alpha-galactosidase
RAM_46125	COG2188	Transcriptional regulator
RAM_46130	COG1397	ADP-ribosylglycohydrolase
RAM_46135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_46150	COG0596	Alpha beta hydrolase
RAM_46155	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
RAM_46160	COG0745	RESPONSE REGULATOR receiver
RAM_46160	COG3706	GGDEF domain
RAM_46170	COG1316	TRANSCRIPTIONal
RAM_46180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RAM_46185	COG0581	inorganic phosphate transmembrane transporter activity
RAM_46195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RAM_46205	COG0745	RESPONSE REGULATOR receiver
RAM_46240	COG4044	May play a role in the intracellular transport of hydrophobic ligands
RAM_46245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RAM_46250	COG1984	allophanate hydrolase subunit 2
RAM_46300	COG3845	ABC transporter
RAM_46335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RAM_46400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RAM_46410	COG1132	(ABC) transporter
RAM_46415	COG0047	phosphoribosylformylglycinamidine synthase activity
RAM_46420	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RAM_46465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RAM_46480	COG1126	abc transporter atp-binding protein
RAM_46485	COG0765	amino acid transport
RAM_46495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_46505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RAM_46510	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_46525	COG2186	Transcriptional regulator
RAM_46550	COG0546	phosphoglycolate phosphatase activity
RAM_46565	COG0436	Aminotransferase
RAM_46570	COG5280	Phage tail tape measure protein TP901
RAM_46570	COG3953	SLT domain
RAM_46605	COG0584	glycerophosphoryl diester phosphodiesterase
RAM_46630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_46640	COG2814	Major facilitator Superfamily
RAM_46645	COG0025	NhaP-type Na H and K H
RAM_46650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_46660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RAM_46695	COG0745	RESPONSE REGULATOR receiver
RAM_46695	COG3706	GGDEF domain
RAM_46730	COG0667	Aldo Keto reductase
RAM_46735	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_46790	COG0586	Pfam SNARE associated Golgi protein
RAM_46805	COG0277	FAD linked oxidase domain protein
RAM_46810	COG3467	pyridoxamine 5'-phosphate
RAM_46830	COG0586	Pfam SNARE associated Golgi protein
RAM_46845	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_46850	COG0572	uridine kinase
RAM_46855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_46890	COG0243	molybdopterin cofactor binding
RAM_46935	COG1136	(ABC) transporter
RAM_46940	COG4221	oxidoreductase activity
RAM_46955	COG0542	response to heat
RAM_46980	COG0412	Dienelactone hydrolase
RAM_46995	COG0789	Transcriptional regulator
RAM_47000	COG0484	heat shock protein binding
RAM_47005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RAM_47010	COG0443	Heat shock 70 kDa protein
RAM_47045	COG2181	nitrate reductase activity
RAM_47045	COG0247	lactate metabolic process
RAM_47060	COG2340	Cysteine-rich secretory protein family
RAM_47095	COG4941	Belongs to the sigma-70 factor family
RAM_47100	COG3795	YCII-related domain
RAM_47105	COG2124	cytochrome p450
RAM_47155	COG3663	DNA glycosylase
RAM_47160	COG2197	response regulator
RAM_47165	COG1960	acyl-CoA dehydrogenase activity
RAM_47175	COG0477	Major facilitator Superfamily
RAM_47195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RAM_47220	COG1126	abc transporter atp-binding protein
RAM_47245	COG1305	Transglutaminase-like
RAM_47260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RAM_47270	COG0022	dehydrogenase e1 component
RAM_47275	COG0508	dehydrogenase complex catalyzes the overall conversion of
RAM_47305	COG3030	protein affecting phage T7 exclusion by the F plasmid
RAM_47345	COG1309	transcriptional regulator
RAM_47350	COG2030	dehydratase
RAM_47355	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_47360	COG0183	Belongs to the thiolase family
RAM_47440	COG1131	(ABC) transporter
RAM_47455	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
RAM_47470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RAM_47485	COG4585	Histidine kinase
RAM_47490	COG2197	response regulator
RAM_47495	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_47515	COG1131	(ABC) transporter
RAM_47530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RAM_47540	COG1136	(ABC) transporter
RAM_47550	COG2197	response regulator
RAM_47565	COG0402	S-adenosylhomocysteine deaminase activity
RAM_47570	COG4221	oxidoreductase activity
RAM_47585	COG2814	Major facilitator Superfamily
RAM_47590	COG1846	Transcriptional regulator
RAM_47595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RAM_47605	COG1595	DNA-templated transcription, initiation
RAM_47615	COG1695	Transcriptional regulator
RAM_47625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RAM_47630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RAM_47635	COG0673	inositol 2-dehydrogenase activity
RAM_47640	COG1940	carbohydrate kinase activity
RAM_47670	COG0360	Binds together with S18 to 16S ribosomal RNA
RAM_47680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RAM_47685	COG0359	binds to the 23S rRNA
RAM_47725	COG3384	dioxygenase
RAM_47750	COG2197	response regulator
RAM_47765	COG0477	Major facilitator Superfamily
RAM_47770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RAM_47780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_47835	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_47840	COG0495	leucyl-tRNA aminoacylation
RAM_47855	COG1678	Uncharacterized ACR, COG1678
RAM_47920	COG0617	tRNA 3'-terminal CCA addition
RAM_47965	COG0492	ferredoxin-NADP+ reductase activity
RAM_47965	COG3118	belongs to the thioredoxin family
RAM_47970	COG0860	N-Acetylmuramoyl-L-alanine amidase
RAM_47970	COG3409	Peptidoglycan-binding domain 1 protein
RAM_47985	COG1181	Belongs to the D-alanine--D-alanine ligase family
RAM_47995	COG1192	Involved in chromosome partitioning
RAM_48000	COG0357	Ribosomal RNA small subunit methyltransferase G
RAM_48015	COG0706	membrane insertase activity
RAM_48020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane