locus-tag	class	description
NQK81_00020	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_00090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NQK81_00095	COG3404	Formiminotransferase-cyclodeaminase
NQK81_00115	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_00130	COG3546	catalase activity
NQK81_00135	COG1295	ribonuclease BN
NQK81_00185	COG0512	Glutamine amidotransferase of anthranilate synthase
NQK81_00185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NQK81_00190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_00195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NQK81_00200	COG0134	indole-3-glycerol-phosphate synthase activity
NQK81_00225	COG2807	transmembrane transport
NQK81_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQK81_00260	COG0667	Aldo Keto reductase
NQK81_00265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_00270	COG1968	undecaprenyl-diphosphatase activity
NQK81_00280	COG0339	signal peptide processing
NQK81_00285	COG1104	cysteine desulfurase activity
NQK81_00290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_00320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NQK81_00340	COG1063	alcohol dehydrogenase
NQK81_00370	COG0039	L-malate dehydrogenase activity
NQK81_00410	COG0477	Major facilitator Superfamily
NQK81_00415	COG3537	Alpha-1,2-mannosidase
NQK81_00425	COG1136	(ABC) transporter
NQK81_00430	COG1136	(ABC) transporter
NQK81_00445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NQK81_00450	COG2084	Dehydrogenase
NQK81_00460	COG0697	spore germination
NQK81_00490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NQK81_00500	COG1309	transcriptional regulator
NQK81_00515	COG2226	methyltransferase
NQK81_00530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQK81_00535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQK81_00535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQK81_00540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NQK81_00550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NQK81_00555	COG0387	Pfam Sodium calcium exchanger
NQK81_00650	COG1120	ATPase activity
NQK81_00655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NQK81_00675	COG2197	response regulator
NQK81_00680	COG4585	Histidine kinase
NQK81_00725	COG0028	Belongs to the TPP enzyme family
NQK81_00735	COG2080	2 iron, 2 sulfur cluster binding
NQK81_00740	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NQK81_00745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NQK81_00765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQK81_00775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQK81_00780	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NQK81_00780	COG2508	Transcriptional regulator
NQK81_00800	COG1522	sequence-specific DNA binding
NQK81_00805	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NQK81_00840	COG0477	Major facilitator Superfamily
NQK81_00850	COG3971	2-oxopent-4-enoate hydratase activity
NQK81_00855	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NQK81_00860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQK81_00875	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
NQK81_00885	COG0583	DNA-binding transcription factor activity
NQK81_00890	COG2272	Belongs to the type-B carboxylesterase lipase family
NQK81_00895	COG0025	NhaP-type Na H and K H
NQK81_00940	COG4974	Belongs to the 'phage' integrase family
NQK81_00955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQK81_01045	COG1129	ABC transporter
NQK81_01050	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQK81_01055	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQK81_01225	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
NQK81_01630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NQK81_01645	COG0671	phosphoesterase, PA-phosphatase related
NQK81_01695	COG0789	Transcriptional regulator
NQK81_01735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQK81_01755	COG4974	Belongs to the 'phage' integrase family
NQK81_01785	COG1051	belongs to the nudix hydrolase family
NQK81_01795	COG0587	DNA-directed DNA polymerase activity
NQK81_01890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NQK81_02145	COG0529	Catalyzes the synthesis of activated sulfate
NQK81_02240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQK81_02260	COG2175	clavaminate synthase activity
NQK81_02280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NQK81_02330	COG1793	dna ligase
NQK81_02335	COG4974	Belongs to the 'phage' integrase family
NQK81_02350	COG0183	Belongs to the thiolase family
NQK81_02385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_02390	COG0477	Major facilitator Superfamily
NQK81_02395	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQK81_02395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQK81_02595	COG1509	lysine 2,3-aminomutase activity
NQK81_02600	COG1228	amidohydrolase
NQK81_02610	COG0463	Glycosyl transferase, family 2
NQK81_02630	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_02640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQK81_02650	COG1435	thymidine kinase activity
NQK81_02675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NQK81_02680	COG0640	Transcriptional regulator
NQK81_02705	COG1733	regulation of RNA biosynthetic process
NQK81_02710	COG0702	epimerase
NQK81_02715	COG2226	methyltransferase
NQK81_02720	COG2226	methyltransferase
NQK81_02725	COG2890	protein-(glutamine-N5) methyltransferase activity
NQK81_02735	COG2318	DinB family
NQK81_02740	COG1595	DNA-templated transcription, initiation
NQK81_02750	COG1309	transcriptional regulator
NQK81_02755	COG1960	acyl-CoA dehydrogenase activity
NQK81_02775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NQK81_02830	COG0702	epimerase
NQK81_02850	COG1357	PFAM Pentapeptide repeats (8 copies)
NQK81_02860	COG2755	lipolytic protein G-D-S-L family
NQK81_02900	COG1309	transcriptional regulator
NQK81_02910	COG2226	methyltransferase
NQK81_02920	COG0596	Alpha beta hydrolase
NQK81_02955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQK81_02965	COG1522	sequence-specific DNA binding
NQK81_02975	COG0590	tRNA wobble adenosine to inosine editing
NQK81_02980	COG4974	Belongs to the 'phage' integrase family
NQK81_03010	COG0583	DNA-binding transcription factor activity
NQK81_03015	COG1846	Transcriptional regulator
NQK81_03020	COG0596	Alpha beta hydrolase
NQK81_03025	COG1309	transcriptional regulator
NQK81_03080	COG1309	transcriptional regulator
NQK81_03090	COG0640	Transcriptional regulator
NQK81_03105	COG2814	Major facilitator Superfamily
NQK81_03155	COG1619	proteins homologs of microcin C7 resistance protein MccF
NQK81_03185	COG0601	transmembrane transport
NQK81_03240	COG0183	Belongs to the thiolase family
NQK81_03255	COG1595	DNA-templated transcription, initiation
NQK81_03265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NQK81_03285	COG0488	(ABC) transporter
NQK81_03295	COG2362	D-Aminopeptidase
NQK81_03300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQK81_03315	COG4221	oxidoreductase activity
NQK81_03320	COG0583	DNA-binding transcription factor activity
NQK81_03375	COG4552	Acetyltransferase involved in intracellular survival and related
NQK81_03385	COG4552	Acetyltransferase involved in intracellular survival and related
NQK81_03405	COG1597	lipid kinase activity
NQK81_03415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NQK81_03425	COG2378	regulation of single-species biofilm formation
NQK81_03435	COG1733	regulation of RNA biosynthetic process
NQK81_03440	COG2130	NADP-dependent
NQK81_03460	COG0640	Transcriptional regulator
NQK81_03470	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NQK81_03475	COG1597	lipid kinase activity
NQK81_03480	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NQK81_03485	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NQK81_03500	COG1051	belongs to the nudix hydrolase family
NQK81_03525	COG1222	aaa ATPase
NQK81_03545	COG1994	Peptidase M50
NQK81_03545	COG0517	IMP dehydrogenase activity
NQK81_03560	COG1192	Involved in chromosome partitioning
NQK81_03565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NQK81_03570	COG0140	phosphoribosyl-ATP diphosphatase activity
NQK81_03585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQK81_03595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NQK81_03600	COG2814	Major facilitator Superfamily
NQK81_03615	COG0488	(ABC) transporter
NQK81_03620	COG0215	cysteine-tRNA ligase activity
NQK81_03625	COG0789	Transcriptional regulator
NQK81_03650	COG0596	Alpha beta hydrolase
NQK81_03655	COG3226	Transcriptional regulator
NQK81_03660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NQK81_03685	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NQK81_03695	COG0477	Major facilitator Superfamily
NQK81_03700	COG0745	RESPONSE REGULATOR receiver
NQK81_03705	COG2205	protein histidine kinase activity
NQK81_03725	COG3540	Alkaline phosphatase
NQK81_03730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NQK81_03735	COG2304	oxidoreductase activity
NQK81_03745	COG0714	Associated with various cellular activities
NQK81_03750	COG0746	molybdenum cofactor guanylyltransferase activity
NQK81_03755	COG0791	NLP P60 protein
NQK81_03755	COG3883	PFAM NLP P60 protein
NQK81_03760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NQK81_03770	COG1285	pathogenesis
NQK81_03780	COG0477	Major facilitator Superfamily
NQK81_03805	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NQK81_03810	COG0121	glutamine amidotransferase
NQK81_03815	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NQK81_03820	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NQK81_03825	COG0583	DNA-binding transcription factor activity
NQK81_03835	COG2267	carboxylic ester hydrolase activity
NQK81_03885	COG0656	L-ascorbic acid biosynthetic process
NQK81_03900	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NQK81_03900	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NQK81_03925	COG1716	ATPase activity
NQK81_03930	COG0509	glycine decarboxylation via glycine cleavage system
NQK81_03985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQK81_04005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NQK81_04005	COG1648	precorrin-2 dehydrogenase activity
NQK81_04020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NQK81_04025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NQK81_04030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NQK81_04040	COG0254	rRNA binding
NQK81_04050	COG0523	cobalamin synthesis protein
NQK81_04060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_04065	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_04080	COG0640	Transcriptional regulator
NQK81_04110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_04135	COG1414	Transcriptional regulator
NQK81_04145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQK81_04160	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_04165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_04170	COG1132	(ABC) transporter
NQK81_04175	COG1132	(ABC) transporter
NQK81_04180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NQK81_04205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NQK81_04220	COG1653	transport
NQK81_04230	COG0395	ABC-type sugar transport system, permease component
NQK81_04235	COG0488	(ABC) transporter
NQK81_04245	COG1024	Enoyl-CoA hydratase
NQK81_04255	COG1595	DNA-templated transcription, initiation
NQK81_04350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NQK81_04350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NQK81_04365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_04370	COG1388	LysM domain
NQK81_04370	COG0791	NLP P60 protein
NQK81_04370	COG3103	Sh3 type 3 domain protein
NQK81_04415	COG0477	Major facilitator Superfamily
NQK81_04425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NQK81_04435	COG3938	Belongs to the proline racemase family
NQK81_04440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQK81_04470	COG0006	proline dipeptidase activity
NQK81_04475	COG0583	DNA-binding transcription factor activity
NQK81_04500	COG1366	Belongs to the anti-sigma-factor antagonist family
NQK81_04510	COG1119	ATPase activity
NQK81_04520	COG2197	response regulator
NQK81_04525	COG4585	Histidine kinase
NQK81_04545	COG0129	dihydroxy-acid dehydratase activity
NQK81_04560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NQK81_04565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_04575	COG4977	sequence-specific DNA binding
NQK81_04655	COG0747	negative chemotaxis
NQK81_04660	COG0601	transmembrane transport
NQK81_04680	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_04685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NQK81_04700	COG0657	acetylesterase activity
NQK81_04710	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_04715	COG1802	Transcriptional regulator
NQK81_04730	COG5504	Zn-dependent protease
NQK81_04765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQK81_04770	COG0477	Major facilitator Superfamily
NQK81_04780	COG1120	ATPase activity
NQK81_04785	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_04790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_04795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NQK81_04800	COG2375	cellular response to nickel ion
NQK81_04805	COG1535	isochorismatase
NQK81_04805	COG3433	isochorismatase activity
NQK81_04810	COG3433	isochorismatase activity
NQK81_04810	COG1535	isochorismatase
NQK81_04815	COG1021	2,3-dihydroxybenzoate-AMP ligase
NQK81_04820	COG1169	isochorismate synthase
NQK81_04825	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_04835	COG2205	protein histidine kinase activity
NQK81_04840	COG0745	RESPONSE REGULATOR receiver
NQK81_04855	COG4977	sequence-specific DNA binding
NQK81_04865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NQK81_04865	COG0825	malonyl-CoA metabolic process
NQK81_04870	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_04880	COG2186	Transcriptional regulator
NQK81_04885	COG1309	transcriptional regulator
NQK81_04895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_04905	COG0277	FAD linked oxidase domain protein
NQK81_04910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NQK81_04915	COG1414	Transcriptional regulator
NQK81_04925	COG3903	Transcriptional regulator
NQK81_04925	COG3629	intracellular signal transduction
NQK81_04930	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NQK81_04930	COG1082	Xylose isomerase domain protein TIM barrel
NQK81_04935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQK81_04945	COG0477	Major facilitator Superfamily
NQK81_04965	COG1609	Transcriptional regulator
NQK81_04975	COG1175	transmembrane transport
NQK81_04985	COG0366	Alpha amylase catalytic
NQK81_04990	COG3629	intracellular signal transduction
NQK81_04990	COG3903	Transcriptional regulator
NQK81_04995	COG1764	response to oxidative stress
NQK81_05035	COG0667	Aldo Keto reductase
NQK81_05050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQK81_05060	COG4209	transmembrane transport
NQK81_05065	COG0395	ABC-type sugar transport system, permease component
NQK81_05080	COG1609	Transcriptional regulator
NQK81_05095	COG0515	serine threonine protein kinase
NQK81_05095	COG2815	serine threonine protein kinase
NQK81_05100	COG1609	Transcriptional regulator
NQK81_05130	COG0583	DNA-binding transcription factor activity
NQK81_05135	COG0277	FAD linked oxidase domain protein
NQK81_05140	COG1160	GTP binding
NQK81_05155	COG1752	Esterase of the alpha-beta hydrolase superfamily
NQK81_05170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NQK81_05205	COG3226	Transcriptional regulator
NQK81_05225	COG0714	Associated with various cellular activities
NQK81_05230	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NQK81_05270	COG0673	inositol 2-dehydrogenase activity
NQK81_05340	COG2814	Major facilitator Superfamily
NQK81_05375	COG0583	DNA-binding transcription factor activity
NQK81_05385	COG2132	Multicopper oxidase
NQK81_05415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQK81_05425	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_05445	COG2326	polyphosphate kinase activity
NQK81_05495	COG1619	proteins homologs of microcin C7 resistance protein MccF
NQK81_05545	COG2197	response regulator
NQK81_05565	COG0583	DNA-binding transcription factor activity
NQK81_05590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQK81_05620	COG0596	Alpha beta hydrolase
NQK81_05645	COG3268	Saccharopine dehydrogenase
NQK81_05650	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_05665	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NQK81_05670	COG0477	Major facilitator Superfamily
NQK81_05675	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_05680	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NQK81_05695	COG1960	acyl-CoA dehydrogenase activity
NQK81_05715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_05770	COG0515	serine threonine protein kinase
NQK81_05770	COG2815	serine threonine protein kinase
NQK81_05780	COG1674	ftsk spoiiie
NQK81_05860	COG5290	Psort location Cytoplasmic, score
NQK81_05895	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NQK81_05940	COG0736	holo-[acyl-carrier-protein] synthase activity
NQK81_05960	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NQK81_05970	COG0736	holo-[acyl-carrier-protein] synthase activity
NQK81_05990	COG3629	intracellular signal transduction
NQK81_05990	COG3903	Transcriptional regulator
NQK81_06010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NQK81_06035	COG2826	transposase and inactivated derivatives, IS30 family
NQK81_06080	COG2850	peptidyl-arginine hydroxylation
NQK81_06110	COG0142	geranyltranstransferase activity
NQK81_06185	COG1609	Transcriptional regulator
NQK81_06190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQK81_06205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_06210	COG1120	ATPase activity
NQK81_06220	COG1132	(ABC) transporter
NQK81_06225	COG1132	(ABC) transporter
NQK81_06240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQK81_06250	COG2197	response regulator
NQK81_06255	COG2197	response regulator
NQK81_06265	COG4946	Tricorn protease homolog
NQK81_06265	COG1506	peptidase
NQK81_06265	COG0823	Involved in the tonB-independent uptake of proteins
NQK81_06345	COG1222	aaa ATPase
NQK81_06375	COG0596	Alpha beta hydrolase
NQK81_06395	COG0531	amino acid
NQK81_06415	COG4977	sequence-specific DNA binding
NQK81_06425	COG0456	acetyltransferase
NQK81_06430	COG2356	endonuclease I
NQK81_06465	COG2197	response regulator
NQK81_06500	COG1335	isochorismatase
NQK81_06505	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NQK81_06555	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NQK81_06575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NQK81_06580	COG0723	plastoquinol--plastocyanin reductase activity
NQK81_06585	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NQK81_06600	COG2890	protein-(glutamine-N5) methyltransferase activity
NQK81_06615	COG0438	transferase activity, transferring glycosyl groups
NQK81_06635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NQK81_06640	COG2192	nodulation
NQK81_06645	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NQK81_06650	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NQK81_06650	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NQK81_06655	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_06735	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_06745	COG0475	glutathione-regulated potassium exporter activity
NQK81_06750	COG1834	amidinotransferase
NQK81_06755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NQK81_06790	COG0069	glutamate synthase activity
NQK81_06795	COG0017	Asparaginyl-tRNA synthetase
NQK81_06825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQK81_06825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQK81_06875	COG3655	Transcriptional regulator
NQK81_06885	COG1573	uracil-dna glycosylase
NQK81_06895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_06955	COG0028	Belongs to the TPP enzyme family
NQK81_06960	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_06965	COG1309	transcriptional regulator
NQK81_06970	COG1733	regulation of RNA biosynthetic process
NQK81_06975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NQK81_06985	COG2124	cytochrome p450
NQK81_07000	COG1414	Transcriptional regulator
NQK81_07005	COG0154	amidase activity
NQK81_07030	COG1053	succinate dehydrogenase
NQK81_07035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_07060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_07100	COG0697	spore germination
NQK81_07105	COG3903	Transcriptional regulator
NQK81_07105	COG3629	intracellular signal transduction
NQK81_07115	COG3706	GGDEF domain
NQK81_07125	COG0745	RESPONSE REGULATOR receiver
NQK81_07130	COG2205	protein histidine kinase activity
NQK81_07145	COG0328	RNA-DNA hybrid ribonuclease activity
NQK81_07150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQK81_07180	COG3706	GGDEF domain
NQK81_07195	COG0439	Biotin carboxylase
NQK81_07205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NQK81_07215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NQK81_07230	COG2855	membrane
NQK81_07250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQK81_07250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NQK81_07260	COG0739	heme binding
NQK81_07285	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NQK81_07300	COG1793	dna ligase
NQK81_07300	COG3285	dna ligase
NQK81_07305	COG1793	dna ligase
NQK81_07315	COG0477	Major facilitator Superfamily
NQK81_07320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_07350	COG1846	Transcriptional regulator
NQK81_07365	COG2826	transposase and inactivated derivatives, IS30 family
NQK81_07370	COG0564	pseudouridine synthase activity
NQK81_07395	COG2124	cytochrome p450
NQK81_07415	COG0431	NADPH-dependent FMN reductase
NQK81_07420	COG1940	carbohydrate kinase activity
NQK81_07425	COG0531	amino acid
NQK81_07445	COG0484	heat shock protein binding
NQK81_07460	COG3795	YCII-related domain
NQK81_07465	COG4941	Belongs to the sigma-70 factor family
NQK81_07495	COG0717	Belongs to the dCTP deaminase family
NQK81_07500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NQK81_07520	COG1960	acyl-CoA dehydrogenase activity
NQK81_07525	COG1960	acyl-CoA dehydrogenase activity
NQK81_07530	COG1960	acyl-CoA dehydrogenase activity
NQK81_07540	COG1309	transcriptional regulator
NQK81_07560	COG2091	lysine biosynthetic process via aminoadipic acid
NQK81_07575	COG1960	acyl-CoA dehydrogenase activity
NQK81_07585	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQK81_07600	COG3321	synthase
NQK81_07600	COG0604	alcohol dehydrogenase
NQK81_07605	COG0604	alcohol dehydrogenase
NQK81_07605	COG3321	synthase
NQK81_07615	COG0604	alcohol dehydrogenase
NQK81_07615	COG3321	synthase
NQK81_07625	COG0604	alcohol dehydrogenase
NQK81_07625	COG3321	synthase
NQK81_07645	COG0477	Major facilitator Superfamily
NQK81_07685	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_07690	COG1309	transcriptional regulator
NQK81_07695	COG0477	Major facilitator Superfamily
NQK81_07715	COG3469	chitinase activity
NQK81_07740	COG1309	transcriptional regulator
NQK81_07760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQK81_07765	COG1960	acyl-CoA dehydrogenase activity
NQK81_07780	COG1309	transcriptional regulator
NQK81_07805	COG1024	Enoyl-CoA hydratase
NQK81_07815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQK81_07815	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NQK81_07820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQK81_07825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NQK81_07850	COG1316	TRANSCRIPTIONal
NQK81_07855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NQK81_07860	COG2267	carboxylic ester hydrolase activity
NQK81_07865	COG4821	SIS domain
NQK81_07875	COG1132	(ABC) transporter
NQK81_07890	COG0488	(ABC) transporter
NQK81_07905	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NQK81_07915	COG2200	EAL domain
NQK81_07915	COG2199	diguanylate cyclase activity
NQK81_07945	COG0175	sulfate reduction
NQK81_07960	COG2197	response regulator
NQK81_07965	COG4585	Histidine kinase
NQK81_07980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NQK81_07990	COG1742	UPF0060 membrane protein
NQK81_07995	COG2151	metal-sulfur cluster biosynthetic enzyme
NQK81_08010	COG0396	ATPase activity
NQK81_08045	COG1612	heme a metabolic process
NQK81_08095	COG0109	protoheme IX farnesyltransferase activity
NQK81_08105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NQK81_08110	COG0166	Belongs to the GPI family
NQK81_08125	COG0363	glucosamine-6-phosphate deaminase activity
NQK81_08145	COG0149	triose-phosphate isomerase activity
NQK81_08150	COG0126	phosphoglycerate kinase activity
NQK81_08155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NQK81_08170	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NQK81_08220	COG3250	beta-galactosidase activity
NQK81_08225	COG1309	transcriptional regulator
NQK81_08235	COG0463	Glycosyl transferase, family 2
NQK81_08250	COG0297	glycogen (starch) synthase activity
NQK81_08265	COG1481	regulation of sporulation
NQK81_08275	COG1660	Displays ATPase and GTPase activities
NQK81_08280	COG0322	excinuclease ABC activity
NQK81_08300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NQK81_08305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQK81_08305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQK81_08320	COG4585	Histidine kinase
NQK81_08325	COG2197	response regulator
NQK81_08345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NQK81_08350	COG0405	Gamma-glutamyltransferase
NQK81_08360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NQK81_08365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NQK81_08375	COG1758	RNA polymerase activity
NQK81_08380	COG0194	GDP metabolic process
NQK81_08390	COG0284	orotidine-5'-phosphate decarboxylase activity
NQK81_08400	COG0505	Belongs to the CarA family
NQK81_08415	COG0540	Belongs to the ATCase OTCase family
NQK81_08420	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NQK81_08430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQK81_08435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NQK81_08440	COG0006	proline dipeptidase activity
NQK81_08455	COG0346	lactoylglutathione lyase activity
NQK81_08460	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NQK81_08465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NQK81_08475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQK81_08480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NQK81_08515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQK81_08520	COG2188	Transcriptional regulator
NQK81_08525	COG1263	PTS System
NQK81_08530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQK81_08540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQK81_08565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NQK81_08570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQK81_08585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NQK81_08625	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NQK81_08630	COG0235	Class ii aldolase
NQK81_08635	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NQK81_08640	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NQK81_08650	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NQK81_08655	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQK81_08665	COG3845	ABC transporter
NQK81_08705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NQK81_08735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NQK81_08740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NQK81_08750	COG0446	pyridine nucleotide-disulphide oxidoreductase
NQK81_08765	COG2326	polyphosphate kinase activity
NQK81_08770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NQK81_08790	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NQK81_08835	COG1793	dna ligase
NQK81_08850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NQK81_08855	COG0506	proline dehydrogenase activity
NQK81_08860	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_08865	COG2508	Transcriptional regulator
NQK81_08865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NQK81_08870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_08880	COG1793	dna ligase
NQK81_08880	COG3285	dna ligase
NQK81_08895	COG2815	serine threonine protein kinase
NQK81_08895	COG0515	serine threonine protein kinase
NQK81_08905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NQK81_08930	COG3220	belongs to the UPF0276 family
NQK81_08940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NQK81_08945	COG3253	May function as heme-dependent peroxidase
NQK81_08955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NQK81_09170	COG1388	LysM domain
NQK81_09170	COG3942	CHAP domain
NQK81_09195	COG2197	response regulator
NQK81_09205	COG1309	transcriptional regulator
NQK81_09220	COG3665	Urea carboxylase-associated protein
NQK81_09240	COG2367	Beta-lactamase
NQK81_09245	COG0183	Belongs to the thiolase family
NQK81_09250	COG1024	Enoyl-CoA hydratase
NQK81_09250	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQK81_09265	COG0656	L-ascorbic acid biosynthetic process
NQK81_09270	COG2205	protein histidine kinase activity
NQK81_09275	COG0745	RESPONSE REGULATOR receiver
NQK81_09285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQK81_09300	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_09310	COG0300	oxidoreductase activity
NQK81_09315	COG1309	transcriptional regulator
NQK81_09325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NQK81_09330	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_09360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NQK81_09365	COG0531	amino acid
NQK81_09370	COG0569	domain protein
NQK81_09400	COG0756	dUTP diphosphatase activity
NQK81_09420	COG0483	inositol monophosphate 1-phosphatase activity
NQK81_09475	COG2197	response regulator
NQK81_09480	COG0531	amino acid
NQK81_09510	COG1309	transcriptional regulator
NQK81_09520	COG4214	carbohydrate transport
NQK81_09530	COG4213	ABC transporter substrate-binding protein
NQK81_09545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NQK81_09570	COG2313	pseudouridylate synthase activity
NQK81_09590	COG2890	protein-(glutamine-N5) methyltransferase activity
NQK81_09595	COG1490	D-aminoacyl-tRNA deacylase activity
NQK81_09605	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NQK81_09605	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NQK81_09640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQK81_09645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQK81_09650	COG2188	Transcriptional regulator
NQK81_09660	COG2070	2-Nitropropane dioxygenase
NQK81_09670	COG1024	Enoyl-CoA hydratase
NQK81_09700	COG1295	ribonuclease BN
NQK81_09710	COG2124	cytochrome p450
NQK81_09715	COG0183	Belongs to the thiolase family
NQK81_09730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NQK81_09730	COG0456	acetyltransferase
NQK81_09735	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_09745	COG1024	Enoyl-CoA hydratase
NQK81_09765	COG0596	Alpha beta hydrolase
NQK81_09780	COG0110	maltose O-acetyltransferase activity
NQK81_09820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQK81_09830	COG2814	Major facilitator Superfamily
NQK81_09835	COG0183	Belongs to the thiolase family
NQK81_09840	COG1309	transcriptional regulator
NQK81_09845	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_09850	COG1960	acyl-CoA dehydrogenase activity
NQK81_09855	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_09860	COG1024	Enoyl-CoA hydratase
NQK81_09865	COG1960	acyl-CoA dehydrogenase activity
NQK81_09870	COG1960	acyl-CoA dehydrogenase activity
NQK81_09875	COG1960	acyl-CoA dehydrogenase activity
NQK81_09915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQK81_09920	COG0346	lactoylglutathione lyase activity
NQK81_09925	COG2267	carboxylic ester hydrolase activity
NQK81_09930	COG1960	acyl-CoA dehydrogenase activity
NQK81_09940	COG1053	succinate dehydrogenase
NQK81_09960	COG2030	dehydratase
NQK81_09970	COG0196	riboflavin kinase activity
NQK81_09980	COG0183	Belongs to the thiolase family
NQK81_09995	COG1960	acyl-CoA dehydrogenase activity
NQK81_10000	COG1960	acyl-CoA dehydrogenase activity
NQK81_10010	COG0657	acetylesterase activity
NQK81_10020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NQK81_10025	COG1960	acyl-CoA dehydrogenase activity
NQK81_10030	COG1309	transcriptional regulator
NQK81_10035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_10045	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NQK81_10045	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NQK81_10045	COG1703	isobutyryl-CoA mutase activity
NQK81_10060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NQK81_10075	COG2018	Roadblock/LC7 domain
NQK81_10090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQK81_10105	COG2814	Major facilitator Superfamily
NQK81_10140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NQK81_10145	COG1960	acyl-CoA dehydrogenase activity
NQK81_10160	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_10165	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NQK81_10165	COG1672	PFAM Archaeal ATPase
NQK81_10185	COG1946	Acyl-CoA thioesterase
NQK81_10220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NQK81_10230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQK81_10255	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NQK81_10265	COG1940	carbohydrate kinase activity
NQK81_10275	COG0003	Pfam Anion-transporting ATPase
NQK81_10310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_10360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NQK81_10365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NQK81_10375	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_10385	COG1960	acyl-CoA dehydrogenase activity
NQK81_10390	COG1960	acyl-CoA dehydrogenase activity
NQK81_10395	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_10405	COG1309	transcriptional regulator
NQK81_10420	COG0123	including yeast histone deacetylase and acetoin utilization protein
NQK81_10435	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NQK81_10455	COG2936	dipeptidyl-peptidase activity
NQK81_10480	COG1505	serine-type exopeptidase activity
NQK81_10490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NQK81_10525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQK81_10530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NQK81_10540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NQK81_10550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NQK81_10570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NQK81_10580	COG1196	nuclear chromosome segregation
NQK81_10595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQK81_10605	COG2205	protein histidine kinase activity
NQK81_10610	COG0745	RESPONSE REGULATOR receiver
NQK81_10615	COG1126	abc transporter atp-binding protein
NQK81_10620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQK81_10625	COG0765	amino acid transport
NQK81_10630	COG0765	amino acid transport
NQK81_10635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NQK81_10650	COG1053	succinate dehydrogenase
NQK81_10670	COG0800	Aldolase
NQK81_10690	COG2137	regulation of response to DNA damage stimulus
NQK81_10695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NQK81_10705	COG0443	Heat shock 70 kDa protein
NQK81_10710	COG1201	RNA secondary structure unwinding
NQK81_10715	COG0242	peptide deformylase activity
NQK81_10785	COG0142	geranyltranstransferase activity
NQK81_10800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_10830	COG0702	epimerase
NQK81_10840	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NQK81_10845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NQK81_10850	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NQK81_10860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NQK81_10865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQK81_10880	COG0768	penicillin binding
NQK81_10890	COG0275	rRNA processing
NQK81_10895	COG2001	Belongs to the MraZ family
NQK81_10940	COG0714	Associated with various cellular activities
NQK81_10950	COG1305	Transglutaminase-like
NQK81_10960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQK81_10970	COG1192	Involved in chromosome partitioning
NQK81_10975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NQK81_10980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NQK81_10990	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_10995	COG1309	transcriptional regulator
NQK81_11000	COG0167	dihydroorotate dehydrogenase activity
NQK81_11005	COG0154	amidase activity
NQK81_11015	COG1842	Phage shock protein A
NQK81_11030	COG1396	sequence-specific DNA binding
NQK81_11035	COG1058	Belongs to the CinA family
NQK81_11035	COG1546	Belongs to the CinA family
NQK81_11045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQK81_11050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NQK81_11060	COG0596	Alpha beta hydrolase
NQK81_11075	COG1674	ftsk spoiiie
NQK81_11085	COG0655	NAD(P)H dehydrogenase (quinone) activity
NQK81_11115	COG1113	amino acid transport
NQK81_11125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NQK81_11130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQK81_11135	COG0515	serine threonine protein kinase
NQK81_11160	COG3214	Protein conserved in bacteria
NQK81_11185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NQK81_11195	COG1185	polyribonucleotide nucleotidyltransferase activity
NQK81_11200	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NQK81_11220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NQK81_11255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NQK81_11280	COG0779	Required for maturation of 30S ribosomal subunits
NQK81_11320	COG1733	regulation of RNA biosynthetic process
NQK81_11335	COG2936	dipeptidyl-peptidase activity
NQK81_11350	COG0745	RESPONSE REGULATOR receiver
NQK81_11355	COG2972	Histidine kinase
NQK81_11355	COG2205	protein histidine kinase activity
NQK81_11360	COG0583	DNA-binding transcription factor activity
NQK81_11365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NQK81_11370	COG1024	Enoyl-CoA hydratase
NQK81_11380	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQK81_11385	COG1960	acyl-CoA dehydrogenase activity
NQK81_11395	COG1316	TRANSCRIPTIONal
NQK81_11430	COG0477	Major facilitator Superfamily
NQK81_11435	COG0789	Transcriptional regulator
NQK81_11470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQK81_11525	COG0475	glutathione-regulated potassium exporter activity
NQK81_11530	COG3033	Beta-eliminating lyase
NQK81_11535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQK81_11535	COG2022	thiamine diphosphate biosynthetic process
NQK81_11550	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_11565	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NQK81_11570	COG0174	glutamine synthetase
NQK81_11580	COG1607	acyl-coa hydrolase
NQK81_11585	COG2072	flavoprotein involved in K transport
NQK81_11590	COG0657	acetylesterase activity
NQK81_11640	COG5002	protein histidine kinase activity
NQK81_11640	COG3850	Histidine kinase
NQK81_11705	COG0137	argininosuccinate synthase activity
NQK81_11740	COG3629	intracellular signal transduction
NQK81_11740	COG3903	Transcriptional regulator
NQK81_11750	COG2207	Transcriptional regulator
NQK81_11755	COG2223	nitrite transmembrane transporter activity
NQK81_11775	COG2267	carboxylic ester hydrolase activity
NQK81_11780	COG2072	flavoprotein involved in K transport
NQK81_11800	COG3647	Membrane
NQK81_11805	COG0531	amino acid
NQK81_11825	COG3629	intracellular signal transduction
NQK81_11825	COG3903	Transcriptional regulator
NQK81_11835	COG1278	Cold shock
NQK81_11915	COG2203	Gaf domain
NQK81_11915	COG4585	Histidine kinase
NQK81_11945	COG4106	trans-aconitate 2-methyltransferase activity
NQK81_11960	COG1595	DNA-templated transcription, initiation
NQK81_11965	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NQK81_11985	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NQK81_11995	COG2197	response regulator
NQK81_12000	COG4585	Histidine kinase
NQK81_12010	COG1131	(ABC) transporter
NQK81_12015	COG0423	glycine-tRNA ligase activity
NQK81_12050	COG0701	Predicted permease
NQK81_12060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NQK81_12065	COG1381	Involved in DNA repair and RecF pathway recombination
NQK81_12105	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NQK81_12120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NQK81_12130	COG0537	adenosine 5'-monophosphoramidase activity
NQK81_12140	COG0484	heat shock protein binding
NQK81_12145	COG1420	regulation of RNA biosynthetic process
NQK81_12180	COG2205	protein histidine kinase activity
NQK81_12185	COG0745	RESPONSE REGULATOR receiver
NQK81_12190	COG1953	Uracil, thiamine, allantoin
NQK81_12200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NQK81_12285	COG2192	nodulation
NQK81_12355	COG2732	(Barnase) inhibitor
NQK81_12370	COG0604	alcohol dehydrogenase
NQK81_12380	COG0531	amino acid
NQK81_12385	COG2070	2-Nitropropane dioxygenase
NQK81_12400	COG0481	GTPase activity
NQK81_12405	COG2226	methyltransferase
NQK81_12420	COG0268	Binds directly to 16S ribosomal RNA
NQK81_12435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQK81_12440	COG1555	photosystem II stabilization
NQK81_12445	COG1307	EDD domain protein, DegV family
NQK81_12455	COG0406	alpha-ribazole phosphatase activity
NQK81_12460	COG0799	negative regulation of ribosome biogenesis
NQK81_12465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NQK81_12475	COG0477	Major facilitator Superfamily
NQK81_12480	COG0018	arginyl-trna synthetase
NQK81_12485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQK81_12500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NQK81_12505	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NQK81_12510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NQK81_12515	COG1530	ribonuclease E activity
NQK81_12520	COG1404	Belongs to the peptidase S8 family
NQK81_12525	COG0842	Transport permease protein
NQK81_12535	COG1131	(ABC) transporter
NQK81_12555	COG0105	UTP biosynthetic process
NQK81_12560	COG1733	regulation of RNA biosynthetic process
NQK81_12575	COG2366	antibiotic biosynthetic process
NQK81_12585	COG0285	dihydrofolate synthase activity
NQK81_12600	COG0525	valine-tRNA ligase activity
NQK81_12625	COG1316	TRANSCRIPTIONal
NQK81_12630	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_12645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NQK81_12675	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NQK81_12680	COG0740	serine-type endopeptidase activity
NQK81_12690	COG0544	peptidyl-prolyl cis-trans isomerase activity
NQK81_12695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NQK81_12700	COG2205	protein histidine kinase activity
NQK81_12705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NQK81_12715	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NQK81_12745	COG1846	Transcriptional regulator
NQK81_12750	COG2814	Major facilitator Superfamily
NQK81_12760	COG0501	Belongs to the peptidase M48B family
NQK81_12775	COG0515	serine threonine protein kinase
NQK81_12775	COG2815	serine threonine protein kinase
NQK81_12790	COG0693	protein deglycase activity
NQK81_12805	COG0784	Response regulator, receiver
NQK81_12805	COG5002	protein histidine kinase activity
NQK81_12860	COG0270	DNA (cytosine-5-)-methyltransferase activity
NQK81_12945	COG2186	Transcriptional regulator
NQK81_12955	COG1051	belongs to the nudix hydrolase family
NQK81_12990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQK81_13005	COG4941	Belongs to the sigma-70 factor family
NQK81_13035	COG0698	ribose 5-phosphate isomerase
NQK81_13050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NQK81_13060	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NQK81_13080	COG0668	transmembrane transport
NQK81_13090	COG0366	Alpha amylase catalytic
NQK81_13125	COG2902	Dehydrogenase
NQK81_13165	COG1609	Transcriptional regulator
NQK81_13490	COG0577	efflux transmembrane transporter activity
NQK81_13490	COG1136	(ABC) transporter
NQK81_13495	COG0577	efflux transmembrane transporter activity
NQK81_13495	COG1136	(ABC) transporter
NQK81_13505	COG2205	protein histidine kinase activity
NQK81_13510	COG0745	RESPONSE REGULATOR receiver
NQK81_13535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQK81_13550	COG1733	regulation of RNA biosynthetic process
NQK81_13560	COG1113	amino acid transport
NQK81_13570	COG1846	Transcriptional regulator
NQK81_13580	COG1793	dna ligase
NQK81_13580	COG3285	dna ligase
NQK81_13585	COG1793	dna ligase
NQK81_13585	COG3285	dna ligase
NQK81_13635	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NQK81_13640	COG2197	response regulator
NQK81_13645	COG4977	sequence-specific DNA binding
NQK81_13645	COG1917	Cupin 2, conserved barrel domain protein
NQK81_13655	COG2197	response regulator
NQK81_13665	COG1733	regulation of RNA biosynthetic process
NQK81_13670	COG0009	L-threonylcarbamoyladenylate synthase
NQK81_13680	COG2197	response regulator
NQK81_13730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQK81_13770	COG2124	cytochrome p450
NQK81_13790	COG1917	Cupin 2, conserved barrel domain protein
NQK81_13790	COG4977	sequence-specific DNA binding
NQK81_13810	COG1733	regulation of RNA biosynthetic process
NQK81_13835	COG3795	YCII-related domain
NQK81_13840	COG1937	Protein conserved in bacteria
NQK81_13880	COG2267	carboxylic ester hydrolase activity
NQK81_13885	COG4221	oxidoreductase activity
NQK81_13895	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NQK81_13950	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_13985	COG0581	inorganic phosphate transmembrane transporter activity
NQK81_13990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NQK81_14010	COG2130	NADP-dependent
NQK81_14025	COG0596	Alpha beta hydrolase
NQK81_14065	COG1609	Transcriptional regulator
NQK81_14080	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NQK81_14085	COG0745	RESPONSE REGULATOR receiver
NQK81_14095	COG1136	(ABC) transporter
NQK81_14100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQK81_14175	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_14180	COG1024	Enoyl-CoA hydratase
NQK81_14300	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_14310	COG1643	Atp-dependent helicase
NQK81_14320	COG0475	glutathione-regulated potassium exporter activity
NQK81_14345	COG3268	Saccharopine dehydrogenase
NQK81_14350	COG1796	DNA polymerase
NQK81_14350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NQK81_14360	COG1802	Transcriptional regulator
NQK81_14380	COG3706	GGDEF domain
NQK81_14385	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NQK81_14390	COG0010	Belongs to the arginase family
NQK81_14400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NQK81_14410	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NQK81_14410	COG0235	Class ii aldolase
NQK81_14420	COG4552	Acetyltransferase involved in intracellular survival and related
NQK81_14435	COG1309	transcriptional regulator
NQK81_14460	COG0277	FAD linked oxidase domain protein
NQK81_14460	COG0247	lactate metabolic process
NQK81_14470	COG2197	response regulator
NQK81_14485	COG0559	Belongs to the binding-protein-dependent transport system permease family
NQK81_14490	COG0559	Belongs to the binding-protein-dependent transport system permease family
NQK81_14505	COG1522	sequence-specific DNA binding
NQK81_14520	COG1739	Uncharacterized protein family UPF0029
NQK81_14525	COG0069	glutamate synthase activity
NQK81_14525	COG0067	glutamate synthase
NQK81_14525	COG0070	glutamate synthase
NQK81_14560	COG1492	cobalamin metabolic process
NQK81_14565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NQK81_14575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NQK81_14580	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NQK81_14590	COG0789	Transcriptional regulator
NQK81_14605	COG1797	cobyrinic acid a,c-diamide synthase activity
NQK81_14645	COG3973	AAA domain
NQK81_14650	COG2319	Wd-40 repeat
NQK81_14650	COG4249	Peptidase C14 caspase catalytic subunit p20
NQK81_14675	COG1131	(ABC) transporter
NQK81_14685	COG1476	TRANSCRIPTIONal
NQK81_14705	COG1929	Belongs to the glycerate kinase type-1 family
NQK81_14715	COG5002	protein histidine kinase activity
NQK81_14730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NQK81_14740	COG0488	(ABC) transporter
NQK81_14745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NQK81_14750	COG2151	metal-sulfur cluster biosynthetic enzyme
NQK81_14755	COG3396	Phenylacetate-CoA oxygenase
NQK81_14760	COG3460	Phenylacetate-CoA oxygenase
NQK81_14765	COG3396	Phenylacetate-CoA oxygenase
NQK81_14770	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_14770	COG2030	dehydratase
NQK81_14785	COG1309	transcriptional regulator
NQK81_14810	COG2072	flavoprotein involved in K transport
NQK81_14825	COG2183	response to ionizing radiation
NQK81_14840	COG0513	Belongs to the DEAD box helicase family
NQK81_14850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NQK81_14855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQK81_14870	COG4585	Histidine kinase
NQK81_14875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NQK81_14880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NQK81_14890	COG3540	Alkaline phosphatase
NQK81_14895	COG4991	sh3 domain protein
NQK81_14900	COG3629	intracellular signal transduction
NQK81_14900	COG3903	Transcriptional regulator
NQK81_14905	COG4991	sh3 domain protein
NQK81_14975	COG1131	(ABC) transporter
NQK81_14995	COG1126	abc transporter atp-binding protein
NQK81_15000	COG0765	amino acid transport
NQK81_15005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQK81_15120	COG2304	oxidoreductase activity
NQK81_15165	COG2365	Tyrosine phosphatase family
NQK81_15170	COG1335	isochorismatase
NQK81_15190	COG2197	response regulator
NQK81_15215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQK81_15230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NQK81_15340	COG0667	Aldo Keto reductase
NQK81_15350	COG1733	regulation of RNA biosynthetic process
NQK81_15355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQK81_15360	COG1024	Enoyl-CoA hydratase
NQK81_15365	COG1024	Enoyl-CoA hydratase
NQK81_15370	COG1024	Enoyl-CoA hydratase
NQK81_15440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NQK81_15455	COG2226	methyltransferase
NQK81_15465	COG1819	glycosyl
NQK81_15470	COG1819	glycosyl
NQK81_15475	COG2124	cytochrome p450
NQK81_15480	COG2124	cytochrome p450
NQK81_15485	COG2124	cytochrome p450
NQK81_15490	COG2124	cytochrome p450
NQK81_15520	COG1132	(ABC) transporter
NQK81_15535	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NQK81_15605	COG0300	oxidoreductase activity
NQK81_15645	COG2124	cytochrome p450
NQK81_15655	COG0697	spore germination
NQK81_15665	COG1725	Transcriptional regulator
NQK81_15675	COG3511	phospholipase C
NQK81_15685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQK81_15730	COG1132	(ABC) transporter
NQK81_15730	COG2375	cellular response to nickel ion
NQK81_15735	COG1132	(ABC) transporter
NQK81_15740	COG4552	Acetyltransferase involved in intracellular survival and related
NQK81_15745	COG2814	Major facilitator Superfamily
NQK81_15750	COG1846	Transcriptional regulator
NQK81_15780	COG2207	Transcriptional regulator
NQK81_15785	COG5650	phosphatidylinositol metabolic process
NQK81_15835	COG4977	sequence-specific DNA binding
NQK81_15845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NQK81_15890	COG3291	Pkd domain containing protein
NQK81_15905	COG0084	hydrolase, TatD family'
NQK81_15915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NQK81_15925	COG0673	inositol 2-dehydrogenase activity
NQK81_15935	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQK81_15940	COG1129	ABC transporter
NQK81_15950	COG1940	carbohydrate kinase activity
NQK81_15955	COG0477	Major facilitator Superfamily
NQK81_15965	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NQK81_15970	COG4565	transcriptional regulatory protein
NQK81_15975	COG3290	protein histidine kinase activity
NQK81_16060	COG2255	four-way junction helicase activity
NQK81_16080	COG2181	nitrate reductase activity
NQK81_16080	COG0247	lactate metabolic process
NQK81_16090	COG1121	(ABC) transporter
NQK81_16095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NQK81_16100	COG1120	ATPase activity
NQK81_16115	COG0326	Molecular chaperone. Has ATPase activity
NQK81_16135	COG3835	regulator
NQK81_16150	COG0596	Alpha beta hydrolase
NQK81_16180	COG1309	transcriptional regulator
NQK81_16205	COG2182	Extracellular solute-binding protein
NQK81_16210	COG1175	transmembrane transport
NQK81_16215	COG0395	ABC-type sugar transport system, permease component
NQK81_16220	COG1472	Belongs to the glycosyl hydrolase 3 family
NQK81_16225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_16230	COG2084	Dehydrogenase
NQK81_16240	COG0438	transferase activity, transferring glycosyl groups
NQK81_16245	COG0483	inositol monophosphate 1-phosphatase activity
NQK81_16270	COG0297	glycogen (starch) synthase activity
NQK81_16290	COG1942	4-Oxalocrotonate Tautomerase
NQK81_16330	COG1793	dna ligase
NQK81_16330	COG3285	dna ligase
NQK81_16375	COG0667	Aldo Keto reductase
NQK81_16390	COG3795	YCII-related domain
NQK81_16400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_16415	COG0187	DNA topoisomerase II activity
NQK81_16430	COG2801	Transposase and inactivated derivatives
NQK81_16435	COG1960	acyl-CoA dehydrogenase activity
NQK81_16440	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_16445	COG2030	dehydratase
NQK81_16455	COG0183	Belongs to the thiolase family
NQK81_16475	COG0583	DNA-binding transcription factor activity
NQK81_16490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQK81_16495	COG1643	Atp-dependent helicase
NQK81_16505	COG1131	(ABC) transporter
NQK81_16530	COG2197	response regulator
NQK81_16535	COG4585	Histidine kinase
NQK81_16550	COG1228	amidohydrolase
NQK81_16555	COG0402	S-adenosylhomocysteine deaminase activity
NQK81_16565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NQK81_16570	COG2986	histidine ammonia-lyase
NQK81_16585	COG0596	Alpha beta hydrolase
NQK81_16610	COG4585	Histidine kinase
NQK81_16615	COG2197	response regulator
NQK81_16635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NQK81_16640	COG2177	Part of the ABC transporter FtsEX involved in
NQK81_16645	COG2884	Cell division ATP-binding protein ftsE
NQK81_16650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NQK81_16680	COG1615	UPF0182 protein
NQK81_16690	COG3480	Lon protease (S16) C-terminal proteolytic domain
NQK81_16710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NQK81_16765	COG0174	glutamine synthetase
NQK81_16775	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NQK81_16785	COG0505	Belongs to the CarA family
NQK81_16795	COG1522	sequence-specific DNA binding
NQK81_16815	COG0154	amidase activity
NQK81_16820	COG0174	glutamine synthetase
NQK81_16845	COG0653	protein targeting
NQK81_16850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NQK81_16850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQK81_16865	COG2318	DinB family
NQK81_16870	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NQK81_16870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NQK81_16875	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NQK81_16885	COG0596	Alpha beta hydrolase
NQK81_16890	COG1177	transmembrane transport
NQK81_16895	COG1176	ABC-type spermidine putrescine transport system, permease component I
NQK81_16900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NQK81_16905	COG3842	ATPase activity
NQK81_16910	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_16935	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_16945	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NQK81_17035	COG2197	response regulator
NQK81_17060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NQK81_17090	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NQK81_17100	COG3265	gluconokinase activity
NQK81_17110	COG0640	Transcriptional regulator
NQK81_17125	COG1486	melibiose metabolic process
NQK81_17130	COG0395	ABC-type sugar transport system, permease component
NQK81_17135	COG1175	transmembrane transport
NQK81_17150	COG1309	transcriptional regulator
NQK81_17170	COG0612	Peptidase, M16
NQK81_17220	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NQK81_17225	COG0714	Associated with various cellular activities
NQK81_17270	COG0210	DNA helicase
NQK81_17285	COG4585	Histidine kinase
NQK81_17295	COG2378	regulation of single-species biofilm formation
NQK81_17310	COG0745	RESPONSE REGULATOR receiver
NQK81_17315	COG2146	nitrite reductase [NAD(P)H] activity
NQK81_17315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQK81_17320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQK81_17320	COG2146	nitrite reductase [NAD(P)H] activity
NQK81_17330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQK81_17335	COG0243	molybdopterin cofactor binding
NQK81_17375	COG0596	Alpha beta hydrolase
NQK81_17385	COG0402	S-adenosylhomocysteine deaminase activity
NQK81_17400	COG2267	carboxylic ester hydrolase activity
NQK81_17435	COG0513	Belongs to the DEAD box helicase family
NQK81_17460	COG2095	MarC family integral membrane protein
NQK81_17465	COG0613	PHP domain protein
NQK81_17495	COG0598	Magnesium transport protein CorA
NQK81_17515	COG1309	transcriptional regulator
NQK81_17580	COG0330	HflC and HflK could
NQK81_17590	COG2239	Acts as a magnesium transporter
NQK81_17605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NQK81_17610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQK81_17635	COG2814	Major facilitator Superfamily
NQK81_17640	COG0583	DNA-binding transcription factor activity
NQK81_17645	COG0671	phosphoesterase, PA-phosphatase related
NQK81_17650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NQK81_17660	COG1024	Enoyl-CoA hydratase
NQK81_17665	COG0519	Catalyzes the synthesis of GMP from XMP
NQK81_17700	COG1271	oxidase subunit
NQK81_17705	COG1294	oxidase, subunit
NQK81_17710	COG4988	ABC transporter
NQK81_17715	COG1132	(ABC) transporter
NQK81_17720	COG0463	Glycosyl transferase, family 2
NQK81_17735	COG1611	Belongs to the LOG family
NQK81_17780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQK81_17790	COG2171	N-acyltransferase activity
NQK81_17830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NQK81_17835	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NQK81_17835	COG0778	Nitroreductase
NQK81_17855	COG1725	Transcriptional regulator
NQK81_17880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NQK81_17900	COG0438	transferase activity, transferring glycosyl groups
NQK81_17930	COG1316	TRANSCRIPTIONal
NQK81_17935	COG1316	TRANSCRIPTIONal
NQK81_17945	COG2259	Doxx family
NQK81_17965	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_17995	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NQK81_18035	COG0477	Major facilitator Superfamily
NQK81_18045	COG2197	response regulator
NQK81_18050	COG2197	response regulator
NQK81_18065	COG2205	protein histidine kinase activity
NQK81_18070	COG0745	RESPONSE REGULATOR receiver
NQK81_18075	COG0483	inositol monophosphate 1-phosphatase activity
NQK81_18105	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NQK81_18105	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NQK81_18110	COG0791	NLP P60 protein
NQK81_18110	COG1388	LysM domain
NQK81_18110	COG3103	Sh3 type 3 domain protein
NQK81_18160	COG0823	Involved in the tonB-independent uptake of proteins
NQK81_18160	COG1506	peptidase
NQK81_18160	COG4946	Tricorn protease homolog
NQK81_18170	COG0640	Transcriptional regulator
NQK81_18185	COG2249	NAD(P)H dehydrogenase (quinone) activity
NQK81_18190	COG4585	Histidine kinase
NQK81_18195	COG2197	response regulator
NQK81_18200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQK81_18225	COG1472	Belongs to the glycosyl hydrolase 3 family
NQK81_18230	COG0424	maF-like protein
NQK81_18235	COG1301	dicarboxylic acid transport
NQK81_18250	COG4770	biotin carboxylase activity
NQK81_18265	COG1278	Cold shock
NQK81_18280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NQK81_18285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NQK81_18290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NQK81_18325	COG1473	amidohydrolase
NQK81_18325	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NQK81_18350	COG0515	serine threonine protein kinase
NQK81_18380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQK81_18405	COG1228	amidohydrolase
NQK81_18420	COG0667	Aldo Keto reductase
NQK81_18425	COG0667	Aldo Keto reductase
NQK81_18430	COG0789	Transcriptional regulator
NQK81_18470	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NQK81_18475	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_18480	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_18500	COG0395	ABC-type sugar transport system, permease component
NQK81_18515	COG1063	alcohol dehydrogenase
NQK81_18525	COG1733	regulation of RNA biosynthetic process
NQK81_18550	COG2271	Major facilitator Superfamily
NQK81_18555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NQK81_18575	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQK81_18585	COG3845	ABC transporter
NQK81_18590	COG1744	ABC transporter substrate-binding protein PnrA-like
NQK81_18595	COG2009	succinate dehydrogenase
NQK81_18610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NQK81_18625	COG1404	Belongs to the peptidase S8 family
NQK81_18635	COG1686	Belongs to the peptidase S11 family
NQK81_18640	COG1295	ribonuclease BN
NQK81_18645	COG0180	Tryptophanyl-tRNA synthetase
NQK81_18685	COG1234	tRNA 3'-trailer cleavage
NQK81_18710	COG2264	protein methyltransferase activity
NQK81_18730	COG0667	Aldo Keto reductase
NQK81_18775	COG2814	Major facilitator Superfamily
NQK81_18780	COG0640	Transcriptional regulator
NQK81_18785	COG2814	Major facilitator Superfamily
NQK81_18820	COG0587	DNA-directed DNA polymerase activity
NQK81_18870	COG0138	bifunctional purine biosynthesis protein purh
NQK81_18895	COG0045	succinate-CoA ligase (ADP-forming) activity
NQK81_18910	COG0739	heme binding
NQK81_18945	COG0515	serine threonine protein kinase
NQK81_18950	COG0515	serine threonine protein kinase
NQK81_18960	COG0583	DNA-binding transcription factor activity
NQK81_19000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NQK81_19000	COG0519	Catalyzes the synthesis of GMP from XMP
NQK81_19010	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_19015	COG0277	FAD linked oxidase domain protein
NQK81_19020	COG1120	ATPase activity
NQK81_19025	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_19030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_19035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NQK81_19055	COG0516	GMP reductase activity
NQK81_19105	COG0459	protein refolding
NQK81_19110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NQK81_19125	COG1215	transferase activity, transferring glycosyl groups
NQK81_19145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NQK81_19150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NQK81_19155	COG0456	acetyltransferase
NQK81_19165	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_19170	COG0825	malonyl-CoA metabolic process
NQK81_19170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NQK81_19175	COG0802	atpase or kinase
NQK81_19185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NQK81_19190	COG3842	ATPase activity
NQK81_19195	COG1070	Carbohydrate kinase
NQK81_19200	COG1349	DNA-binding transcription factor activity
NQK81_19210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NQK81_19235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NQK81_19265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQK81_19270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NQK81_19275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NQK81_19305	COG0443	Heat shock 70 kDa protein
NQK81_19310	COG1674	ftsk spoiiie
NQK81_19320	COG1404	Belongs to the peptidase S8 family
NQK81_19355	COG0101	tRNA pseudouridine synthase activity
NQK81_19360	COG0203	ribosomal protein L17
NQK81_19365	COG0202	RNA polymerase activity
NQK81_19370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NQK81_19375	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NQK81_19390	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NQK81_19395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NQK81_19405	COG0563	adenylate kinase activity
NQK81_19425	COG0200	Binds to the 23S rRNA
NQK81_19430	COG1841	ribosomal large subunit assembly
NQK81_19435	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NQK81_19440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NQK81_19445	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NQK81_19450	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NQK81_19460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NQK81_19465	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NQK81_19470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NQK81_19475	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NQK81_19480	COG0255	Belongs to the universal ribosomal protein uL29 family
NQK81_19490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NQK81_19495	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NQK81_19500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NQK81_19505	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NQK81_19510	COG0089	rRNA binding
NQK81_19515	COG0088	Forms part of the polypeptide exit tunnel
NQK81_19520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NQK81_19525	COG0051	transcription antitermination factor activity, RNA binding
NQK81_19535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQK81_19540	COG0049	tRNA binding
NQK81_19545	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NQK81_19605	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NQK81_19615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NQK81_19645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NQK81_19670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NQK81_19685	COG0222	ribosome binding
NQK81_19705	COG0081	regulation of translation
NQK81_19735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_19755	COG2030	dehydratase
NQK81_19760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NQK81_19790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NQK81_19810	COG0586	Pfam SNARE associated Golgi protein
NQK81_19815	COG4585	Histidine kinase
NQK81_19820	COG2201	protein-glutamate methylesterase activity
NQK81_19825	COG0640	Transcriptional regulator
NQK81_19830	COG0346	lactoylglutathione lyase activity
NQK81_19845	COG1309	transcriptional regulator
NQK81_19860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NQK81_19885	COG1666	GTP binding
NQK81_19905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_19910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_19915	COG0501	Belongs to the peptidase M48B family
NQK81_19945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NQK81_19960	COG4310	Domain of unknown function (DUF2172)
NQK81_19970	COG1216	Glycosyl transferase, family 2
NQK81_19970	COG0463	Glycosyl transferase, family 2
NQK81_19980	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NQK81_19985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NQK81_20030	COG0367	asparagine synthase
NQK81_20050	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NQK81_20070	COG1834	amidinotransferase
NQK81_20075	COG1522	sequence-specific DNA binding
NQK81_20085	COG0674	pyruvate-flavodoxin oxidoreductase activity
NQK81_20085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NQK81_20090	COG1013	pyruvate-flavodoxin oxidoreductase activity
NQK81_20100	COG0142	geranyltranstransferase activity
NQK81_20125	COG1196	nuclear chromosome segregation
NQK81_20165	COG1007	ATP synthesis coupled electron transport
NQK81_20175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NQK81_20180	COG0713	ATP synthesis coupled electron transport
NQK81_20185	COG0839	Belongs to the complex I subunit 6 family
NQK81_20190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQK81_20195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NQK81_20200	COG1034	ATP synthesis coupled electron transport
NQK81_20215	COG0649	NAD binding
NQK81_20220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQK81_20225	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQK81_20240	COG2226	methyltransferase
NQK81_20250	COG0438	transferase activity, transferring glycosyl groups
NQK81_20275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NQK81_20280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NQK81_20310	COG1522	sequence-specific DNA binding
NQK81_20330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NQK81_20340	COG0785	Cytochrome C biogenesis protein
NQK81_20350	COG0406	alpha-ribazole phosphatase activity
NQK81_20355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NQK81_20385	COG1914	H( )-stimulated, divalent metal cation uptake system
NQK81_20390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NQK81_20390	COG1587	Uroporphyrinogen-III synthase
NQK81_20395	COG0181	hydroxymethylbilane synthase activity
NQK81_20400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NQK81_20405	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NQK81_20420	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_20425	COG1595	DNA-templated transcription, initiation
NQK81_20460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NQK81_20490	COG5002	protein histidine kinase activity
NQK81_20505	COG0588	phosphoglycerate mutase activity
NQK81_20520	COG0438	transferase activity, transferring glycosyl groups
NQK81_20525	COG2267	carboxylic ester hydrolase activity
NQK81_20535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NQK81_20565	COG2130	NADP-dependent
NQK81_20590	COG2986	histidine ammonia-lyase
NQK81_20615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NQK81_20620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQK81_20640	COG2733	membrane
NQK81_20660	COG2186	Transcriptional regulator
NQK81_20665	COG2364	Membrane
NQK81_20700	COG3226	Transcriptional regulator
NQK81_20775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NQK81_20790	COG2233	PERMEase
NQK81_20910	COG1278	Cold shock
NQK81_20925	COG1595	DNA-templated transcription, initiation
NQK81_20945	COG0515	serine threonine protein kinase
NQK81_20970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQK81_20980	COG2197	response regulator
NQK81_21010	COG4585	Histidine kinase
NQK81_21015	COG2197	response regulator
NQK81_21035	COG0028	Belongs to the TPP enzyme family
NQK81_21050	COG1132	(ABC) transporter
NQK81_21055	COG1132	(ABC) transporter
NQK81_21065	COG0515	serine threonine protein kinase
NQK81_21105	COG4585	Histidine kinase
NQK81_21110	COG2197	response regulator
NQK81_21120	COG1278	Cold shock
NQK81_21125	COG2233	PERMEase
NQK81_21135	COG0402	S-adenosylhomocysteine deaminase activity
NQK81_21225	COG0789	Transcriptional regulator
NQK81_21265	COG2132	Multicopper oxidase
NQK81_21270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_21295	COG0791	NLP P60 protein
NQK81_21295	COG3103	Sh3 type 3 domain protein
NQK81_21295	COG1388	LysM domain
NQK81_21340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NQK81_21340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NQK81_21345	COG0785	Cytochrome C biogenesis protein
NQK81_21350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NQK81_21365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQK81_21380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NQK81_21435	COG3336	cytochrome c oxidase
NQK81_21440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NQK81_21460	COG0789	Transcriptional regulator
NQK81_21475	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQK81_21485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NQK81_21495	COG0713	ATP synthesis coupled electron transport
NQK81_21500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NQK81_21505	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQK81_21510	COG1007	ATP synthesis coupled electron transport
NQK81_21525	COG2132	Multicopper oxidase
NQK81_21535	COG0785	Cytochrome C biogenesis protein
NQK81_21550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NQK81_21560	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NQK81_21565	COG1138	Cytochrome C-type biogenesis protein
NQK81_21580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NQK81_21605	COG2226	methyltransferase
NQK81_21615	COG0501	Belongs to the peptidase M48B family
NQK81_21665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_21690	COG1388	LysM domain
NQK81_21690	COG3103	Sh3 type 3 domain protein
NQK81_21690	COG0791	NLP P60 protein
NQK81_21745	COG1937	Protein conserved in bacteria
NQK81_21750	COG1937	Protein conserved in bacteria
NQK81_21830	COG0270	DNA (cytosine-5-)-methyltransferase activity
NQK81_21975	COG0714	Associated with various cellular activities
NQK81_22010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQK81_22130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NQK81_22140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NQK81_22175	COG0438	transferase activity, transferring glycosyl groups
NQK81_22220	COG0720	synthase
NQK81_22225	COG0602	queuosine metabolic process
NQK81_22265	COG1484	DNA-dependent DNA replication
NQK81_22285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQK81_22320	COG2826	transposase and inactivated derivatives, IS30 family
NQK81_22325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NQK81_22355	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NQK81_22365	COG1329	Transcriptional regulator
NQK81_22370	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NQK81_22375	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NQK81_22395	COG0215	cysteine-tRNA ligase activity
NQK81_22425	COG1309	transcriptional regulator
NQK81_22450	COG0235	Class ii aldolase
NQK81_22465	COG0698	ribose 5-phosphate isomerase
NQK81_22470	COG2376	Dihydroxyacetone kinase
NQK81_22475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQK81_22485	COG1349	DNA-binding transcription factor activity
NQK81_22490	COG2814	Major facilitator Superfamily
NQK81_22495	COG1070	Carbohydrate kinase
NQK81_22510	COG4399	Belongs to the UPF0754 family
NQK81_22515	COG4399	Belongs to the UPF0754 family
NQK81_22525	COG1120	ATPase activity
NQK81_22530	COG0803	Belongs to the bacterial solute-binding protein 9 family
NQK81_22535	COG1609	Transcriptional regulator
NQK81_22545	COG1194	a g-specific adenine glycosylase
NQK81_22555	COG0596	Alpha beta hydrolase
NQK81_22575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NQK81_22610	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NQK81_22615	COG0443	Heat shock 70 kDa protein
NQK81_22645	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NQK81_22655	COG2226	methyltransferase
NQK81_22660	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NQK81_22665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NQK81_22670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NQK81_22695	COG0789	Transcriptional regulator
NQK81_22710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NQK81_22720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQK81_22760	COG2027	D-alanyl-D-alanine carboxypeptidase
NQK81_22765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NQK81_22770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NQK81_22780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NQK81_22800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQK81_22805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NQK81_22825	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_22830	COG0657	acetylesterase activity
NQK81_22850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NQK81_22855	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NQK81_22890	COG2272	Belongs to the type-B carboxylesterase lipase family
NQK81_22895	COG1754	DNA topoisomerase type I activity
NQK81_22895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NQK81_22920	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NQK81_22925	COG1111	helicase
NQK81_22925	COG1205	dead DEAH box helicase
NQK81_22975	COG1472	Belongs to the glycosyl hydrolase 3 family
NQK81_22980	COG3876	Protein conserved in bacteria
NQK81_22985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NQK81_22990	COG1737	Transcriptional regulator
NQK81_22995	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NQK81_23000	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NQK81_23005	COG2814	Major facilitator Superfamily
NQK81_23010	COG0640	Transcriptional regulator
NQK81_23040	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_23050	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NQK81_23060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQK81_23100	COG3104	oligopeptide transport
NQK81_23105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NQK81_23115	COG0596	Alpha beta hydrolase
NQK81_23130	COG0494	nUDIX hydrolase
NQK81_23135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NQK81_23165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NQK81_23225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQK81_23230	COG1408	metallophosphoesterase
NQK81_23260	COG0076	glutamate decarboxylase activity
NQK81_23265	COG0783	Belongs to the Dps family
NQK81_23270	COG1764	response to oxidative stress
NQK81_23305	COG1690	Belongs to the RtcB family
NQK81_23325	COG0477	Major facilitator Superfamily
NQK81_23360	COG0583	DNA-binding transcription factor activity
NQK81_23365	COG0697	spore germination
NQK81_23375	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_23390	COG4608	Belongs to the ABC transporter superfamily
NQK81_23395	COG0444	Belongs to the ABC transporter superfamily
NQK81_23400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQK81_23405	COG0601	transmembrane transport
NQK81_23410	COG0747	negative chemotaxis
NQK81_23425	COG1216	Glycosyl transferase, family 2
NQK81_23440	COG0463	Glycosyl transferase, family 2
NQK81_23445	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NQK81_23450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NQK81_23455	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NQK81_23460	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQK81_23485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NQK81_23490	COG2205	protein histidine kinase activity
NQK81_23495	COG0745	RESPONSE REGULATOR receiver
NQK81_23515	COG2197	response regulator
NQK81_23545	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQK81_23555	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NQK81_23555	COG5479	isomerase activity
NQK81_23575	COG0631	protein serine/threonine phosphatase activity
NQK81_23620	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
NQK81_23650	COG1473	amidohydrolase
NQK81_23655	COG4702	Belongs to the UPF0303 family
NQK81_23695	COG3973	AAA domain
NQK81_23750	COG0596	Alpha beta hydrolase
NQK81_23755	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NQK81_23770	COG0704	Plays a role in the regulation of phosphate uptake
NQK81_23775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NQK81_23780	COG0581	inorganic phosphate transmembrane transporter activity
NQK81_23800	COG0745	RESPONSE REGULATOR receiver
NQK81_23830	COG4044	May play a role in the intracellular transport of hydrophobic ligands
NQK81_23840	COG1984	allophanate hydrolase subunit 2
NQK81_23855	COG0354	folic acid binding
NQK81_23900	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NQK81_23905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NQK81_23975	COG1132	(ABC) transporter
NQK81_23980	COG1132	(ABC) transporter
NQK81_23985	COG0047	phosphoribosylformylglycinamidine synthase activity
NQK81_23990	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NQK81_24020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NQK81_24025	COG2311	Membrane
NQK81_24040	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NQK81_24055	COG1126	abc transporter atp-binding protein
NQK81_24060	COG0765	amino acid transport
NQK81_24065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQK81_24070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQK81_24080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NQK81_24120	COG0436	Aminotransferase
NQK81_24135	COG5280	Phage tail tape measure protein TP901
NQK81_24135	COG3953	SLT domain
NQK81_24170	COG0584	glycerophosphoryl diester phosphodiesterase
NQK81_24180	COG2814	Major facilitator Superfamily
NQK81_24195	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NQK81_24220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQK81_24225	COG4172	Belongs to the ABC transporter superfamily
NQK81_24290	COG0667	Aldo Keto reductase
NQK81_24295	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_24340	COG0586	Pfam SNARE associated Golgi protein
NQK81_24345	COG0277	FAD linked oxidase domain protein
NQK81_24350	COG0477	Major facilitator Superfamily
NQK81_24360	COG3467	pyridoxamine 5'-phosphate
NQK81_24370	COG0477	Major facilitator Superfamily
NQK81_24375	COG0586	Pfam SNARE associated Golgi protein
NQK81_24385	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_24390	COG1072	(Pantothenic acid kinase))
NQK81_24395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQK81_24420	COG1609	Transcriptional regulator
NQK81_24435	COG0243	molybdopterin cofactor binding
NQK81_24440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQK81_24460	COG1136	(ABC) transporter
NQK81_24460	COG0577	efflux transmembrane transporter activity
NQK81_24470	COG1285	pathogenesis
NQK81_24475	COG0300	oxidoreductase activity
NQK81_24490	COG0542	response to heat
NQK81_24525	COG0789	Transcriptional regulator
NQK81_24530	COG0484	heat shock protein binding
NQK81_24535	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NQK81_24540	COG0443	Heat shock 70 kDa protein
NQK81_24575	COG2076	Multidrug Resistance protein
NQK81_24580	COG0247	lactate metabolic process
NQK81_24580	COG2181	nitrate reductase activity
NQK81_24595	COG2340	Cysteine-rich secretory protein family
NQK81_24610	COG0717	Belongs to the dCTP deaminase family
NQK81_24625	COG2188	Transcriptional regulator
NQK81_24630	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NQK81_24650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NQK81_24675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NQK81_24685	COG0737	Belongs to the 5'-nucleotidase family
NQK81_24710	COG3663	DNA glycosylase
NQK81_24715	COG2197	response regulator
NQK81_24720	COG1960	acyl-CoA dehydrogenase activity
NQK81_24745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NQK81_24800	COG0765	amino acid transport
NQK81_24805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQK81_24820	COG1305	Transglutaminase-like
NQK81_24825	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_24830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_24840	COG0596	Alpha beta hydrolase
NQK81_24845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQK81_24855	COG0022	dehydrogenase e1 component
NQK81_24860	COG0508	dehydrogenase complex catalyzes the overall conversion of
NQK81_24880	COG3030	protein affecting phage T7 exclusion by the F plasmid
NQK81_24895	COG1309	transcriptional regulator
NQK81_24900	COG2030	dehydratase
NQK81_24905	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_24910	COG0183	Belongs to the thiolase family
NQK81_24935	COG0584	glycerophosphoryl diester phosphodiesterase
NQK81_24940	COG0789	Transcriptional regulator
NQK81_24955	COG0456	acetyltransferase
NQK81_25015	COG4133	protoheme IX ABC transporter activity
NQK81_25025	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NQK81_25040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NQK81_25060	COG4585	Histidine kinase
NQK81_25065	COG2197	response regulator
NQK81_25075	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_25095	COG1131	(ABC) transporter
NQK81_25110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NQK81_25120	COG1136	(ABC) transporter
NQK81_25130	COG2197	response regulator
NQK81_25135	COG0402	S-adenosylhomocysteine deaminase activity
NQK81_25140	COG4221	oxidoreductase activity
NQK81_25145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NQK81_25150	COG2226	methyltransferase
NQK81_25170	COG2814	Major facilitator Superfamily
NQK81_25180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQK81_25190	COG1695	Transcriptional regulator
NQK81_25200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQK81_25205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQK81_25210	COG0673	inositol 2-dehydrogenase activity
NQK81_25215	COG1940	carbohydrate kinase activity
NQK81_25255	COG0360	Binds together with S18 to 16S ribosomal RNA
NQK81_25265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NQK81_25270	COG0359	binds to the 23S rRNA
NQK81_25300	COG2267	carboxylic ester hydrolase activity
NQK81_25340	COG3384	dioxygenase
NQK81_25345	COG0738	Major facilitator superfamily
NQK81_25350	COG1940	carbohydrate kinase activity
NQK81_25350	COG1846	Transcriptional regulator
NQK81_25375	COG2197	response regulator
NQK81_25390	COG0477	Major facilitator Superfamily
NQK81_25395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NQK81_25400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQK81_25435	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_25440	COG0495	leucyl-tRNA aminoacylation
NQK81_25515	COG4585	Histidine kinase
NQK81_25520	COG0617	tRNA 3'-terminal CCA addition
NQK81_25545	COG1595	DNA-templated transcription, initiation
NQK81_25560	COG0492	ferredoxin-NADP+ reductase activity
NQK81_25560	COG3118	belongs to the thioredoxin family
NQK81_25565	COG3409	Peptidoglycan-binding domain 1 protein
NQK81_25565	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQK81_25580	COG1181	Belongs to the D-alanine--D-alanine ligase family
NQK81_25595	COG1192	Involved in chromosome partitioning
NQK81_25600	COG0357	Ribosomal RNA small subunit methyltransferase G
NQK81_25610	COG0706	membrane insertase activity
NQK81_25615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NQK81_25635	COG0592	DNA-directed DNA polymerase activity
NQK81_25640	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NQK81_25645	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NQK81_25650	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NQK81_25655	COG0187	DNA topoisomerase II activity
NQK81_25660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NQK81_25710	COG2197	response regulator
NQK81_25715	COG4585	Histidine kinase
NQK81_25775	COG0457	Tetratricopeptide repeat
NQK81_25775	COG0705	Rhomboid family
NQK81_25795	COG3764	Sortase (surface protein transpeptidase)
NQK81_25835	COG0493	'glutamate synthase
NQK81_25865	COG0515	serine threonine protein kinase
NQK81_25870	COG0768	penicillin binding
NQK81_25885	COG1716	ATPase activity
NQK81_25890	COG1716	ATPase activity
NQK81_25915	COG0626	cystathionine gamma-synthase activity
NQK81_25940	COG2186	Transcriptional regulator
NQK81_25945	COG0747	negative chemotaxis
NQK81_25955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQK81_25960	COG0444	Belongs to the ABC transporter superfamily
NQK81_25970	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_25980	COG0154	amidase activity
NQK81_25995	COG2301	Belongs to the HpcH HpaI aldolase family
NQK81_26000	COG0515	serine threonine protein kinase
NQK81_26015	COG0702	epimerase
NQK81_26020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NQK81_26085	COG1276	copper resistance
NQK81_26085	COG2372	response to copper ion
NQK81_26100	COG1174	glycine betaine transport
NQK81_26110	COG1174	glycine betaine transport
NQK81_26135	COG2226	methyltransferase
NQK81_26145	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NQK81_26165	COG0405	Gamma-glutamyltransferase
NQK81_26180	COG0477	Major facilitator Superfamily
NQK81_26195	COG4585	Histidine kinase
NQK81_26200	COG2197	response regulator
NQK81_26230	COG0438	transferase activity, transferring glycosyl groups
NQK81_26230	COG1216	Glycosyl transferase, family 2
NQK81_26300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NQK81_26310	COG3275	phosphorelay sensor kinase activity
NQK81_26335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQK81_26345	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQK81_26385	COG1191	sigma factor activity
NQK81_26400	COG2235	arginine
NQK81_26465	COG1271	oxidase subunit
NQK81_26470	COG1294	oxidase, subunit
NQK81_26475	COG4988	ABC transporter
NQK81_26525	COG2176	DNA-directed DNA polymerase activity
NQK81_26565	COG1072	(Pantothenic acid kinase))
NQK81_26580	COG0406	alpha-ribazole phosphatase activity
NQK81_26615	COG0754	glutathionylspermidine amidase activity
NQK81_26620	COG3766	membrane
NQK81_26625	COG0596	Alpha beta hydrolase
NQK81_26630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NQK81_26635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NQK81_26645	COG0579	oxidoreductase
NQK81_26660	COG0477	Major facilitator Superfamily
NQK81_26685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NQK81_26695	COG0438	transferase activity, transferring glycosyl groups
NQK81_26700	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NQK81_26735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NQK81_26750	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_26755	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_26795	COG0561	phosphatase activity
NQK81_26800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_26820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NQK81_26855	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_26860	COG0277	FAD linked oxidase domain protein
NQK81_26870	COG1216	Glycosyl transferase, family 2
NQK81_26920	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NQK81_26925	COG1216	Glycosyl transferase, family 2
NQK81_26945	COG0596	Alpha beta hydrolase
NQK81_26960	COG3321	synthase
NQK81_26960	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_26960	COG0604	alcohol dehydrogenase
NQK81_26965	COG2234	aminopeptidase activity
NQK81_26990	COG4941	Belongs to the sigma-70 factor family
NQK81_26995	COG3795	YCII-related domain
NQK81_27045	COG0504	CTP synthase activity
NQK81_27055	COG3706	GGDEF domain
NQK81_27060	COG3209	COG3209 Rhs family protein
NQK81_27090	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NQK81_27090	COG1672	PFAM Archaeal ATPase
NQK81_27105	COG1522	sequence-specific DNA binding
NQK81_27125	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NQK81_27130	COG2186	Transcriptional regulator
NQK81_27145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQK81_27170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQK81_27175	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NQK81_27175	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NQK81_27245	COG1309	transcriptional regulator
NQK81_27250	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_27295	COG2172	sigma factor antagonist activity
NQK81_27330	COG3559	Exporter of polyketide antibiotics
NQK81_27335	COG1131	(ABC) transporter
NQK81_27350	COG0702	epimerase
NQK81_27395	COG2175	clavaminate synthase activity
NQK81_27405	COG0287	Prephenate dehydrogenase
NQK81_27410	COG0446	pyridine nucleotide-disulphide oxidoreductase
NQK81_27410	COG1902	pentaerythritol trinitrate reductase activity
NQK81_27425	COG1846	Transcriptional regulator
NQK81_27460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NQK81_27465	COG2318	DinB family
NQK81_27475	COG0210	DNA helicase
NQK81_27515	COG0602	queuosine metabolic process
NQK81_27520	COG0720	synthase
NQK81_27555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NQK81_27565	COG0438	transferase activity, transferring glycosyl groups
NQK81_27580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQK81_27600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NQK81_27610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NQK81_27755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQK81_27900	COG3103	Sh3 type 3 domain protein
NQK81_27900	COG0791	NLP P60 protein
NQK81_27900	COG1388	LysM domain
NQK81_27955	COG0270	DNA (cytosine-5-)-methyltransferase activity
NQK81_27990	COG0477	Major facilitator Superfamily
NQK81_28015	COG4221	oxidoreductase activity
NQK81_28020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_28040	COG1141	Ferredoxin
NQK81_28045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQK81_28060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NQK81_28065	COG1127	ABC transporter
NQK81_28115	COG2197	response regulator
NQK81_28120	COG5002	protein histidine kinase activity
NQK81_28130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQK81_28135	COG0492	ferredoxin-NADP+ reductase activity
NQK81_28140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NQK81_28150	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_28165	COG1127	ABC transporter
NQK81_28180	COG0535	radical SAM domain protein
NQK81_28195	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_28215	COG1366	Belongs to the anti-sigma-factor antagonist family
NQK81_28265	COG2124	cytochrome p450
NQK81_28270	COG1309	transcriptional regulator
NQK81_28275	COG2226	methyltransferase
NQK81_28285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NQK81_28285	COG0425	Belongs to the sulfur carrier protein TusA family
NQK81_28290	COG2814	Major facilitator Superfamily
NQK81_28295	COG1104	cysteine desulfurase activity
NQK81_28385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_28425	COG0501	Belongs to the peptidase M48B family
NQK81_28475	COG0640	Transcriptional regulator
NQK81_28495	COG1595	DNA-templated transcription, initiation
NQK81_28510	COG0583	DNA-binding transcription factor activity
NQK81_28520	COG3795	YCII-related domain
NQK81_28525	COG4941	Belongs to the sigma-70 factor family
NQK81_28545	COG1620	l-lactate permease
NQK81_28555	COG1832	CoA-binding protein
NQK81_28565	COG2826	transposase and inactivated derivatives, IS30 family
NQK81_28570	COG3971	2-oxopent-4-enoate hydratase activity
NQK81_28610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQK81_28620	COG0346	lactoylglutathione lyase activity
NQK81_28625	COG0400	carboxylic ester hydrolase activity
NQK81_28635	COG5416	Lipopolysaccharide assembly protein A domain
NQK81_28660	COG4399	Belongs to the UPF0754 family
NQK81_28665	COG1733	regulation of RNA biosynthetic process
NQK81_28670	COG1752	Esterase of the alpha-beta hydrolase superfamily
NQK81_28675	COG0456	acetyltransferase
NQK81_28685	COG1917	Cupin 2, conserved barrel domain protein
NQK81_28690	COG5285	phytanoyl-CoA dioxygenase
NQK81_28695	COG3903	Transcriptional regulator
NQK81_28695	COG3629	intracellular signal transduction
NQK81_28735	COG2971	BadF BadG BcrA BcrD
NQK81_28740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NQK81_28745	COG2188	Transcriptional regulator
NQK81_28750	COG0477	Major facilitator Superfamily
NQK81_28765	COG0352	thiamine-phosphate diphosphorylase activity
NQK81_28770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQK81_28770	COG2022	thiamine diphosphate biosynthetic process
NQK81_28780	COG2022	thiamine diphosphate biosynthetic process
NQK81_28805	COG1733	regulation of RNA biosynthetic process
NQK81_28815	COG0351	phosphomethylpyrimidine kinase
NQK81_28820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NQK81_28825	COG1280	lysine exporter protein (LysE YggA)
NQK81_28835	COG0242	peptide deformylase activity
NQK81_28850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQK81_28860	COG0688	phosphatidylethanolamine metabolic process
NQK81_28865	COG2261	transglycosylase associated protein
NQK81_28895	COG1278	Cold shock
NQK81_28905	COG0459	protein refolding
NQK81_28935	COG4948	Mandelate Racemase Muconate Lactonizing
NQK81_28940	COG3903	Transcriptional regulator
NQK81_28940	COG3629	intracellular signal transduction
NQK81_28955	COG1061	Type III restriction enzyme res subunit
NQK81_28975	COG3142	Participates in the control of copper homeostasis
NQK81_28985	COG1116	anion transmembrane transporter activity
NQK81_28985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQK81_28990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQK81_28995	COG1174	glycine betaine transport
NQK81_29020	COG2018	Roadblock/LC7 domain
NQK81_29035	COG2018	Roadblock/LC7 domain
NQK81_29070	COG0521	Mo-molybdopterin cofactor biosynthetic process
NQK81_29100	COG1846	Transcriptional regulator
NQK81_29135	COG3304	Inner membrane component domain
NQK81_29140	COG0384	phenazine biosynthesis protein PhzF
NQK81_29145	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_29150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQK81_29170	COG1278	Cold shock
NQK81_29180	COG2814	Major facilitator Superfamily
NQK81_29205	COG2252	PERMEase
NQK81_29215	COG2814	Major facilitator Superfamily
NQK81_29265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQK81_29285	COG2205	protein histidine kinase activity
NQK81_29290	COG0745	RESPONSE REGULATOR receiver
NQK81_29295	COG5183	chlorophyll binding
NQK81_29295	COG2133	pyrroloquinoline quinone binding
NQK81_29310	COG0577	efflux transmembrane transporter activity
NQK81_29310	COG1136	(ABC) transporter
NQK81_29315	COG1136	(ABC) transporter
NQK81_29315	COG0577	efflux transmembrane transporter activity
NQK81_29320	COG5650	phosphatidylinositol metabolic process
NQK81_29340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NQK81_29345	COG2197	response regulator
NQK81_29350	COG4585	Histidine kinase
NQK81_29360	COG1131	(ABC) transporter
NQK81_29390	COG0831	urea catabolic process
NQK81_29395	COG0832	Belongs to the urease beta subunit family
NQK81_29400	COG0804	urea catabolic process
NQK81_29410	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NQK81_29415	COG0829	nickel cation binding
NQK81_29450	COG0642	Histidine kinase
NQK81_29455	COG1116	anion transmembrane transporter activity
NQK81_29460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQK81_29475	COG0259	pyridoxamine-phosphate oxidase activity
NQK81_29505	COG1309	transcriptional regulator
NQK81_29525	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_29530	COG2017	converts alpha-aldose to the beta-anomer
NQK81_29540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NQK81_29550	COG1960	acyl-CoA dehydrogenase activity
NQK81_29570	COG0415	Belongs to the DNA photolyase family
NQK81_29575	COG1668	transmembrane transport
NQK81_29580	COG4152	abc transporter atp-binding protein
NQK81_29610	COG0277	FAD linked oxidase domain protein
NQK81_29650	COG2182	Extracellular solute-binding protein
NQK81_29665	COG1169	isochorismate synthase
NQK81_29675	COG1301	dicarboxylic acid transport
NQK81_29680	COG1960	acyl-CoA dehydrogenase activity
NQK81_29695	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_29700	COG1024	Enoyl-CoA hydratase
NQK81_29705	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NQK81_29715	COG1321	iron dependent repressor
NQK81_29745	COG1984	allophanate hydrolase subunit 2
NQK81_29750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NQK81_29755	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NQK81_29760	COG4336	lyase activity
NQK81_29765	COG2814	Major facilitator Superfamily
NQK81_29780	COG1940	carbohydrate kinase activity
NQK81_29830	COG2755	lipolytic protein G-D-S-L family
NQK81_29830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NQK81_29840	COG0583	DNA-binding transcription factor activity
NQK81_29845	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NQK81_29850	COG0702	epimerase
NQK81_29865	COG4941	Belongs to the sigma-70 factor family
NQK81_29880	COG4221	oxidoreductase activity
NQK81_29925	COG3629	intracellular signal transduction
NQK81_29925	COG3903	Transcriptional regulator
NQK81_29950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NQK81_30005	COG2197	response regulator
NQK81_30010	COG2860	membrane
NQK81_30020	COG2205	protein histidine kinase activity
NQK81_30025	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NQK81_30035	COG1349	DNA-binding transcription factor activity
NQK81_30040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQK81_30075	COG0745	RESPONSE REGULATOR receiver
NQK81_30080	COG5002	protein histidine kinase activity
NQK81_30095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NQK81_30100	COG0315	cyclic pyranopterin monophosphate synthase activity
NQK81_30100	COG0521	Mo-molybdopterin cofactor biosynthetic process
NQK81_30135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQK81_30195	COG0604	alcohol dehydrogenase
NQK81_30195	COG3321	synthase
NQK81_30230	COG0134	indole-3-glycerol-phosphate synthase activity
NQK81_30235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NQK81_30245	COG3483	tryptophan 2,3-dioxygenase activity
NQK81_30255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQK81_30265	COG0596	Alpha beta hydrolase
NQK81_30285	COG0477	Major facilitator Superfamily
NQK81_30330	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NQK81_30335	COG1960	acyl-CoA dehydrogenase activity
NQK81_30365	COG4585	Histidine kinase
NQK81_30370	COG2197	response regulator
NQK81_30415	COG1605	Chorismate mutase
NQK81_30415	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NQK81_30485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NQK81_30495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NQK81_30505	COG2226	methyltransferase
NQK81_30555	COG2318	DinB family
NQK81_30565	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_30580	COG2258	MOSC domain
NQK81_30650	COG1674	ftsk spoiiie
NQK81_30925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQK81_30930	COG0084	hydrolase, TatD family'
NQK81_30950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NQK81_30955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQK81_30960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NQK81_30965	COG0488	(ABC) transporter
NQK81_30970	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_30985	COG0193	aminoacyl-tRNA hydrolase activity
NQK81_31015	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NQK81_31045	COG1335	isochorismatase
NQK81_31055	COG2133	pyrroloquinoline quinone binding
NQK81_31060	COG2197	response regulator
NQK81_31065	COG4585	Histidine kinase
NQK81_31070	COG3963	phosphatidate phosphatase activity
NQK81_31080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_31100	COG1595	DNA-templated transcription, initiation
NQK81_31110	COG1131	(ABC) transporter
NQK81_31140	COG1396	sequence-specific DNA binding
NQK81_31155	COG0148	phosphopyruvate hydratase activity
NQK81_31180	COG4166	transmembrane transport
NQK81_31185	COG0601	transmembrane transport
NQK81_31190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQK81_31195	COG0444	Belongs to the ABC transporter superfamily
NQK81_31200	COG4608	Belongs to the ABC transporter superfamily
NQK81_31205	COG1404	Belongs to the peptidase S8 family
NQK81_31215	COG1515	deoxyribonuclease V activity
NQK81_31225	COG1252	NADH dehydrogenase
NQK81_31240	COG0745	RESPONSE REGULATOR receiver
NQK81_31250	COG2197	response regulator
NQK81_31255	COG4585	Histidine kinase
NQK81_31280	COG0406	alpha-ribazole phosphatase activity
NQK81_31285	COG2124	cytochrome p450
NQK81_31300	COG1472	Belongs to the glycosyl hydrolase 3 family
NQK81_31320	COG0789	Transcriptional regulator
NQK81_31325	COG1902	pentaerythritol trinitrate reductase activity
NQK81_31365	COG2391	methyltransferase activity
NQK81_31370	COG0477	Major facilitator Superfamily
NQK81_31375	COG0183	Belongs to the thiolase family
NQK81_31440	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NQK81_31450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQK81_31455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQK81_31465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NQK81_31475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NQK81_31485	COG1331	Highly conserved protein containing a thioredoxin domain
NQK81_31530	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NQK81_31545	COG1733	regulation of RNA biosynthetic process
NQK81_31580	COG1793	dna ligase
NQK81_31600	COG0114	fumarate hydratase activity
NQK81_31605	COG0492	ferredoxin-NADP+ reductase activity
NQK81_31620	COG1722	exodeoxyribonuclease VII activity
NQK81_31630	COG1570	exodeoxyribonuclease VII activity
NQK81_31640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NQK81_31655	COG0420	3'-5' exonuclease activity
NQK81_31660	COG0419	ATPase involved in DNA repair
NQK81_31675	COG0012	GTP binding
NQK81_31695	COG3654	unkown
NQK81_31720	COG2234	aminopeptidase activity
NQK81_31735	COG2154	pterin-4-alpha-carbinolamine dehydratase
NQK81_31745	COG4149	molybdate abc transporter
NQK81_31750	COG3842	ATPase activity
NQK81_31760	COG1131	(ABC) transporter
NQK81_31775	COG2205	protein histidine kinase activity
NQK81_31780	COG0406	alpha-ribazole phosphatase activity
NQK81_31780	COG0494	nUDIX hydrolase
NQK81_31785	COG0180	Tryptophanyl-tRNA synthetase
NQK81_31800	COG1217	gtp-binding protein TYPA
NQK81_31805	COG0747	negative chemotaxis
NQK81_31815	COG0601	transmembrane transport
NQK81_31830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NQK81_31845	COG1994	Peptidase M50
NQK81_31870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQK81_31875	COG2835	tetraacyldisaccharide 4'-kinase activity
NQK81_31885	COG1482	cell wall glycoprotein biosynthetic process
NQK81_31895	COG3629	intracellular signal transduction
NQK81_31895	COG3903	Transcriptional regulator
NQK81_31905	COG0531	amino acid
NQK81_31945	COG4638	Rieske (2fe-2S)
NQK81_31950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQK81_31965	COG2146	nitrite reductase [NAD(P)H] activity
NQK81_31970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQK81_31975	COG0745	RESPONSE REGULATOR receiver
NQK81_31980	COG5002	protein histidine kinase activity
NQK81_31980	COG5000	phosphorelay sensor kinase activity
NQK81_31995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NQK81_32000	COG0653	protein targeting
NQK81_32005	COG2826	transposase and inactivated derivatives, IS30 family
NQK81_32015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQK81_32020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQK81_32050	COG1162	GTPase activity
NQK81_32055	COG2135	peptidase activity
NQK81_32070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NQK81_32095	COG1597	lipid kinase activity
NQK81_32110	COG0406	alpha-ribazole phosphatase activity
NQK81_32135	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NQK81_32140	COG0281	malic enzyme
NQK81_32165	COG1174	glycine betaine transport
NQK81_32175	COG3153	acetyltransferase
NQK81_32180	COG1404	Belongs to the peptidase S8 family
NQK81_32195	COG0508	dehydrogenase complex catalyzes the overall conversion of
NQK81_32195	COG0567	Dehydrogenase, E1 component
NQK81_32215	COG1132	(ABC) transporter
NQK81_32230	COG0686	Belongs to the AlaDH PNT family
NQK81_32250	COG2508	Transcriptional regulator
NQK81_32250	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NQK81_32260	COG1695	Transcriptional regulator
NQK81_32265	COG0346	lactoylglutathione lyase activity
NQK81_32275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NQK81_32290	COG2755	lipolytic protein G-D-S-L family
NQK81_32295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQK81_32305	COG1960	acyl-CoA dehydrogenase activity
NQK81_32320	COG4221	oxidoreductase activity
NQK81_32330	COG1960	acyl-CoA dehydrogenase activity
NQK81_32350	COG0183	Belongs to the thiolase family
NQK81_32355	COG1024	Enoyl-CoA hydratase
NQK81_32355	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQK81_32360	COG2409	Drug exporters of the RND superfamily
NQK81_32365	COG2197	response regulator
NQK81_32370	COG4585	Histidine kinase
NQK81_32385	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_32395	COG0477	Major facilitator Superfamily
NQK81_32400	COG0028	Belongs to the TPP enzyme family
NQK81_32415	COG3629	intracellular signal transduction
NQK81_32415	COG3903	Transcriptional regulator
NQK81_32430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NQK81_32440	COG0473	3-isopropylmalate dehydrogenase activity
NQK81_32470	COG0154	amidase activity
NQK81_32485	COG0667	Aldo Keto reductase
NQK81_32515	COG2133	pyrroloquinoline quinone binding
NQK81_32525	COG0435	Glutathione S-transferase
NQK81_32575	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NQK81_32625	COG2910	NAD(P)H-binding
NQK81_32640	COG1846	Transcriptional regulator
NQK81_32655	COG4941	Belongs to the sigma-70 factor family
NQK81_32675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NQK81_32690	COG1053	succinate dehydrogenase
NQK81_32700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NQK81_32705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQK81_32710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NQK81_32720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_32755	COG2197	response regulator
NQK81_32760	COG3851	Histidine kinase
NQK81_32770	COG2132	Multicopper oxidase
NQK81_32795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NQK81_32795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NQK81_32810	COG0022	dehydrogenase e1 component
NQK81_32815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NQK81_32830	COG2124	cytochrome p450
NQK81_32835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_32865	COG0596	Alpha beta hydrolase
NQK81_32885	COG0018	arginyl-trna synthetase
NQK81_32890	COG0019	diaminopimelate decarboxylase activity
NQK81_32895	COG0460	homoserine dehydrogenase
NQK81_32900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NQK81_32905	COG0083	homoserine kinase activity
NQK81_32910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NQK81_32910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NQK81_32925	COG0254	rRNA binding
NQK81_32930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NQK81_32950	COG0463	Glycosyl transferase, family 2
NQK81_32965	COG0596	Alpha beta hydrolase
NQK81_32970	COG0789	Transcriptional regulator
NQK81_32980	COG2890	protein-(glutamine-N5) methyltransferase activity
NQK81_32995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQK81_33005	COG0356	it plays a direct role in the translocation of protons across the membrane
NQK81_33010	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQK81_33015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NQK81_33020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQK81_33025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NQK81_33030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NQK81_33035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NQK81_33040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NQK81_33050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NQK81_33065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQK81_33080	COG1280	lysine exporter protein (LysE YggA)
NQK81_33085	COG1280	lysine exporter protein (LysE YggA)
NQK81_33095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NQK81_33095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NQK81_33100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQK81_33105	COG0765	amino acid transport
NQK81_33110	COG0765	amino acid transport
NQK81_33115	COG1126	abc transporter atp-binding protein
NQK81_33125	COG4977	sequence-specific DNA binding
NQK81_33140	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NQK81_33145	COG1752	Esterase of the alpha-beta hydrolase superfamily
NQK81_33175	COG2376	Dihydroxyacetone kinase
NQK81_33180	COG1461	Dihydroxyacetone kinase
NQK81_33190	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQK81_33205	COG1522	sequence-specific DNA binding
NQK81_33210	COG0626	cystathionine gamma-synthase activity
NQK81_33235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NQK81_33260	COG1819	glycosyl
NQK81_33270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NQK81_33275	COG3830	Belongs to the UPF0237 family
NQK81_33275	COG0560	Phosphoserine phosphatase
NQK81_33315	COG0800	Aldolase
NQK81_33320	COG1335	isochorismatase
NQK81_33325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NQK81_33340	COG3191	aminopeptidase activity
NQK81_33360	COG1794	racemase activity, acting on amino acids and derivatives
NQK81_33375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NQK81_33385	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NQK81_33390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NQK81_33430	COG0277	FAD linked oxidase domain protein
NQK81_33440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NQK81_33445	COG2814	Major facilitator Superfamily
NQK81_33455	COG0587	DNA-directed DNA polymerase activity
NQK81_33555	COG1316	TRANSCRIPTIONal
NQK81_33565	COG3706	GGDEF domain
NQK81_33580	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_33600	COG3844	kynureninase activity
NQK81_33615	COG2018	Roadblock/LC7 domain
NQK81_33630	COG2259	Doxx family
NQK81_33635	COG2259	Doxx family
NQK81_33645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQK81_33680	COG1408	metallophosphoesterase
NQK81_33690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NQK81_33735	COG3469	chitinase activity
NQK81_33745	COG0698	ribose 5-phosphate isomerase
NQK81_33765	COG2267	carboxylic ester hydrolase activity
NQK81_33770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NQK81_33780	COG2814	Major facilitator Superfamily
NQK81_33790	COG0673	inositol 2-dehydrogenase activity
NQK81_33810	COG0492	ferredoxin-NADP+ reductase activity
NQK81_33815	COG1309	transcriptional regulator
NQK81_33820	COG1024	Enoyl-CoA hydratase
NQK81_33865	COG4585	Histidine kinase
NQK81_33870	COG2197	response regulator
NQK81_33885	COG1376	ErfK ybiS ycfS ynhG family protein
NQK81_33900	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NQK81_33905	COG0433	COG0433 Predicted ATPase
NQK81_33915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQK81_33925	COG2226	methyltransferase
NQK81_33940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NQK81_33945	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NQK81_33975	COG0346	lactoylglutathione lyase activity
NQK81_33980	COG0183	Belongs to the thiolase family
NQK81_34010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_34015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NQK81_34025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQK81_34035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQK81_34045	COG3279	Response regulator of the LytR AlgR family
NQK81_34050	COG3275	phosphorelay sensor kinase activity
NQK81_34080	COG1609	Transcriptional regulator
NQK81_34085	COG3537	Alpha-1,2-mannosidase
NQK81_34095	COG1846	Transcriptional regulator
NQK81_34120	COG0058	SHG alpha-glucan phosphorylase activity
NQK81_34160	COG1119	ATPase activity
NQK81_34165	COG1024	Enoyl-CoA hydratase
NQK81_34170	COG2226	methyltransferase
NQK81_34260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NQK81_34290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NQK81_34315	COG1595	DNA-templated transcription, initiation
NQK81_34320	COG1252	NADH dehydrogenase
NQK81_34350	COG0791	NLP P60 protein
NQK81_34350	COG3883	PFAM NLP P60 protein
NQK81_34355	COG1957	nucleoside hydrolase
NQK81_34360	COG0110	maltose O-acetyltransferase activity
NQK81_34380	COG0702	epimerase
NQK81_34395	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NQK81_34410	COG3250	beta-galactosidase activity
NQK81_34425	COG0386	Belongs to the glutathione peroxidase family
NQK81_34435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NQK81_34445	COG1307	EDD domain protein, DegV family
NQK81_34455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NQK81_34480	COG0477	Major facilitator Superfamily
NQK81_34490	COG0482	sulfurtransferase activity
NQK81_34495	COG0456	acetyltransferase
NQK81_34500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQK81_34520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NQK81_34540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NQK81_34545	COG0154	amidase activity
NQK81_34590	COG0129	dihydroxy-acid dehydratase activity
NQK81_34605	COG0440	acetolactate synthase activity
NQK81_34610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NQK81_34670	COG1404	Belongs to the peptidase S8 family
NQK81_34675	COG0473	3-isopropylmalate dehydrogenase activity
NQK81_34680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQK81_34685	COG0179	Fumarylacetoacetate (FAA) hydrolase
NQK81_34760	COG3883	PFAM NLP P60 protein
NQK81_34760	COG0791	NLP P60 protein
NQK81_34860	COG2226	methyltransferase
NQK81_34865	COG3706	GGDEF domain
NQK81_34955	COG2814	Major facilitator Superfamily
NQK81_34990	COG1937	Protein conserved in bacteria
NQK81_34995	COG1937	Protein conserved in bacteria
NQK81_35045	COG1366	Belongs to the anti-sigma-factor antagonist family
NQK81_35060	COG1388	LysM domain
NQK81_35060	COG0791	NLP P60 protein
NQK81_35060	COG3103	Sh3 type 3 domain protein
NQK81_35085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_35135	COG0501	Belongs to the peptidase M48B family
NQK81_35145	COG2226	methyltransferase
NQK81_35170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NQK81_35180	COG3088	subunit of a heme lyase
NQK81_35190	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NQK81_35200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NQK81_35215	COG0785	Cytochrome C biogenesis protein
NQK81_35225	COG2132	Multicopper oxidase
NQK81_35240	COG1007	ATP synthesis coupled electron transport
NQK81_35245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQK81_35250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NQK81_35255	COG0713	ATP synthesis coupled electron transport
NQK81_35265	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NQK81_35275	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQK81_35310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQK81_35315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQK81_35320	COG0798	PFAM Bile acid sodium symporter
NQK81_35325	COG2072	flavoprotein involved in K transport
NQK81_35350	COG0640	Transcriptional regulator
NQK81_35360	COG2072	flavoprotein involved in K transport
NQK81_35390	COG0765	amino acid transport
NQK81_35445	COG1937	Protein conserved in bacteria
NQK81_35450	COG1937	Protein conserved in bacteria
NQK81_35475	COG0484	heat shock protein binding
NQK81_35520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQK81_35550	COG0243	molybdopterin cofactor binding
NQK81_35555	COG0443	Heat shock 70 kDa protein
NQK81_35560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NQK81_35575	COG0542	response to heat
NQK81_35615	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_35695	COG0019	diaminopimelate decarboxylase activity
NQK81_35700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_35705	COG0534	Mate efflux family protein
NQK81_35720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NQK81_35740	COG1982	Orn Lys Arg decarboxylase major
NQK81_35805	COG0714	Associated with various cellular activities
NQK81_35860	COG1674	ftsk spoiiie
NQK81_35880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NQK81_35900	COG2205	protein histidine kinase activity
NQK81_35905	COG0745	RESPONSE REGULATOR receiver
NQK81_35915	COG0464	growth
NQK81_35920	COG0745	RESPONSE REGULATOR receiver
NQK81_35935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQK81_35940	COG0066	3-isopropylmalate dehydratase activity
NQK81_35945	COG0776	regulation of translation
NQK81_35950	COG0494	nUDIX hydrolase
NQK81_35950	COG0406	alpha-ribazole phosphatase activity
NQK81_35960	COG1920	GTP binding
NQK81_35970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NQK81_35985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NQK81_36010	COG0745	RESPONSE REGULATOR receiver
NQK81_36015	COG2205	protein histidine kinase activity
NQK81_36025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_36060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NQK81_36065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NQK81_36070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NQK81_36075	COG1461	Dihydroxyacetone kinase
NQK81_36120	COG1404	Belongs to the peptidase S8 family
NQK81_36135	COG3835	regulator
NQK81_36185	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NQK81_36210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NQK81_36220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_36225	COG4249	Peptidase C14 caspase catalytic subunit p20
NQK81_36225	COG2319	Wd-40 repeat
NQK81_36230	COG3973	AAA domain
NQK81_36235	COG0742	ribosomal rna small subunit methyltransferase
NQK81_36240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NQK81_36270	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NQK81_36275	COG0571	ribonuclease III activity
NQK81_36285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NQK81_36320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_36340	COG0174	glutamine synthetase
NQK81_36345	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NQK81_36350	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_36365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NQK81_36365	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NQK81_36370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NQK81_36375	COG0509	glycine decarboxylation via glycine cleavage system
NQK81_36380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NQK81_36385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NQK81_36390	COG1760	l-serine dehydratase
NQK81_36395	COG2186	Transcriptional regulator
NQK81_36400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQK81_36405	COG4122	O-methyltransferase activity
NQK81_36410	COG1120	ATPase activity
NQK81_36415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_36425	COG4221	oxidoreductase activity
NQK81_36440	COG2814	Major facilitator Superfamily
NQK81_36445	COG0179	Fumarylacetoacetate (FAA) hydrolase
NQK81_36450	COG4948	Mandelate Racemase Muconate Lactonizing
NQK81_36465	COG1129	ABC transporter
NQK81_36470	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQK81_36475	COG2186	Transcriptional regulator
NQK81_36530	COG1929	Belongs to the glycerate kinase type-1 family
NQK81_36560	COG1902	pentaerythritol trinitrate reductase activity
NQK81_36565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NQK81_36570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NQK81_36580	COG3485	protocatechuate 3,4-dioxygenase
NQK81_36585	COG3485	protocatechuate 3,4-dioxygenase
NQK81_36590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NQK81_36595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NQK81_36600	COG1414	Transcriptional regulator
NQK81_36615	COG0667	Aldo Keto reductase
NQK81_36640	COG1522	sequence-specific DNA binding
NQK81_36670	COG0492	ferredoxin-NADP+ reductase activity
NQK81_36685	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_36695	COG0583	DNA-binding transcription factor activity
NQK81_36700	COG3962	Belongs to the TPP enzyme family
NQK81_36705	COG3718	enzyme involved in inositol metabolism
NQK81_36710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQK81_36730	COG1082	Xylose isomerase domain protein TIM barrel
NQK81_36735	COG1609	Transcriptional regulator
NQK81_36740	COG0673	inositol 2-dehydrogenase activity
NQK81_36750	COG3903	Transcriptional regulator
NQK81_36750	COG3629	intracellular signal transduction
NQK81_36755	COG1725	Transcriptional regulator
NQK81_36760	COG1131	(ABC) transporter
NQK81_36775	COG0367	asparagine synthase
NQK81_36785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NQK81_36790	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NQK81_36795	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NQK81_36815	COG1254	Belongs to the acylphosphatase family
NQK81_36830	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NQK81_36845	COG0477	Major facilitator Superfamily
NQK81_36855	COG1414	Transcriptional regulator
NQK81_36860	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NQK81_36885	COG1309	transcriptional regulator
NQK81_36910	COG3835	regulator
NQK81_36930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NQK81_36935	COG0590	tRNA wobble adenosine to inosine editing
NQK81_36940	COG2252	PERMEase
NQK81_36955	COG1309	transcriptional regulator
NQK81_36970	COG2351	hydroxyisourate hydrolase activity
NQK81_36985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NQK81_36990	COG4266	Belongs to the allantoicase family
NQK81_37000	COG1832	CoA-binding protein
NQK81_37005	COG2873	o-acetylhomoserine
NQK81_37030	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NQK81_37040	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NQK81_37090	COG0228	four-way junction DNA binding
NQK81_37105	COG0336	Belongs to the RNA methyltransferase TrmD family
NQK81_37110	COG0335	large ribosomal subunit rRNA binding
NQK81_37115	COG0681	Belongs to the peptidase S26 family
NQK81_37120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NQK81_37130	COG0792	nuclease activity
NQK81_37150	COG1191	sigma factor activity
NQK81_37165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NQK81_37170	COG0528	UMP kinase activity
NQK81_37180	COG0575	Belongs to the CDS family
NQK81_37205	COG1695	Transcriptional regulator
NQK81_37230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NQK81_37290	COG1335	isochorismatase
NQK81_37315	COG3540	Alkaline phosphatase
NQK81_37320	COG0604	alcohol dehydrogenase
NQK81_37320	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_37320	COG3321	synthase
NQK81_37360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_37400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQK81_37415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NQK81_37420	COG0750	zinc metalloprotease
NQK81_37425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NQK81_37430	COG0454	-acetyltransferase
NQK81_37430	COG0456	acetyltransferase
NQK81_37435	COG0768	penicillin binding
NQK81_37445	COG2186	Transcriptional regulator
NQK81_37450	COG2807	transmembrane transport
NQK81_37480	COG0156	8-amino-7-oxononanoate synthase activity
NQK81_37485	COG0513	Belongs to the DEAD box helicase family
NQK81_37500	COG1404	Belongs to the peptidase S8 family
NQK81_37520	COG3022	response to hydroperoxide
NQK81_37545	COG0442	prolyl-tRNA aminoacylation
NQK81_37555	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NQK81_37590	COG1396	sequence-specific DNA binding
NQK81_37600	COG2197	response regulator
NQK81_37640	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NQK81_37650	COG0095	Lipoate-protein ligase
NQK81_37685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NQK81_37700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NQK81_37705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NQK81_37715	COG0668	transmembrane transport
NQK81_37720	COG3201	nicotinamide mononucleotide transporter
NQK81_37730	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NQK81_37770	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_37775	COG3226	Transcriptional regulator
NQK81_37795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NQK81_37815	COG1113	amino acid transport
NQK81_37820	COG2186	Transcriptional regulator
NQK81_37835	COG0587	DNA-directed DNA polymerase activity
NQK81_37840	COG0477	Major facilitator Superfamily
NQK81_37865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NQK81_37870	COG1376	ErfK ybiS ycfS ynhG family protein
NQK81_37875	COG1752	Esterase of the alpha-beta hydrolase superfamily
NQK81_37880	COG0586	Pfam SNARE associated Golgi protein
NQK81_37885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NQK81_37900	COG1309	transcriptional regulator
NQK81_37910	COG0321	lipoyl(octanoyl) transferase activity
NQK81_37920	COG1090	epimerase
NQK81_37935	COG0508	dehydrogenase complex catalyzes the overall conversion of
NQK81_37940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQK81_37955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NQK81_37975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NQK81_37985	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NQK81_38000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NQK81_38010	COG0667	Aldo Keto reductase
NQK81_38030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQK81_38045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NQK81_38090	COG1845	cytochrome c oxidase, subunit III
NQK81_38095	COG2010	Cytochrome c
NQK81_38105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NQK81_38135	COG0438	transferase activity, transferring glycosyl groups
NQK81_38150	COG2124	cytochrome p450
NQK81_38155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NQK81_38160	COG0288	reversible hydration of carbon dioxide
NQK81_38165	COG0659	secondary active sulfate transmembrane transporter activity
NQK81_38170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NQK81_38195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NQK81_38205	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NQK81_38210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NQK81_38220	COG1404	Belongs to the peptidase S8 family
NQK81_38270	COG3896	Chloramphenicol phosphotransferase-like protein
NQK81_38285	COG1674	ftsk spoiiie
NQK81_38335	COG2197	response regulator
NQK81_38340	COG3386	PFAM SMP-30 Gluconolaconase
NQK81_38355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NQK81_38365	COG0131	Imidazoleglycerol-phosphate dehydratase
NQK81_38395	COG2409	Drug exporters of the RND superfamily
NQK81_38400	COG1309	transcriptional regulator
NQK81_38410	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NQK81_38420	COG3959	Transketolase, thiamine diphosphate binding domain
NQK81_38425	COG3958	Transketolase
NQK81_38455	COG1960	acyl-CoA dehydrogenase activity
NQK81_38465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NQK81_38470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NQK81_38515	COG1309	transcriptional regulator
NQK81_38520	COG0107	imidazoleglycerol-phosphate synthase activity
NQK81_38530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NQK81_38550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NQK81_38560	COG0134	indole-3-glycerol-phosphate synthase activity
NQK81_38565	COG0133	tryptophan synthase activity
NQK81_38570	COG0159	tryptophan synthase activity
NQK81_38575	COG0174	glutamine synthetase
NQK81_38585	COG1473	amidohydrolase
NQK81_38590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NQK81_38605	COG0067	glutamate synthase
NQK81_38605	COG0070	glutamate synthase
NQK81_38605	COG0069	glutamate synthase activity
NQK81_38615	COG0596	Alpha beta hydrolase
NQK81_38625	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NQK81_38635	COG2318	DinB family
NQK81_38645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NQK81_38680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NQK81_38685	COG1799	cell septum assembly
NQK81_38695	COG3599	regulation of cell shape
NQK81_38725	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NQK81_38735	COG0640	Transcriptional regulator
NQK81_38750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NQK81_38760	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NQK81_38780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_38785	COG0248	Ppx GppA phosphatase
NQK81_38805	COG1309	transcriptional regulator
NQK81_38820	COG1940	carbohydrate kinase activity
NQK81_38835	COG2010	Cytochrome c
NQK81_38835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NQK81_38850	COG0667	Aldo Keto reductase
NQK81_38855	COG2226	methyltransferase
NQK81_38860	COG0667	Aldo Keto reductase
NQK81_38870	COG0477	Major facilitator Superfamily
NQK81_38875	COG0542	response to heat
NQK81_38900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NQK81_38910	COG0514	ATP-dependent DNA helicase (RecQ)
NQK81_38920	COG0640	Transcriptional regulator
NQK81_38955	COG0142	geranyltranstransferase activity
NQK81_38975	COG1051	belongs to the nudix hydrolase family
NQK81_38980	COG0596	Alpha beta hydrolase
NQK81_38995	COG0640	Transcriptional regulator
NQK81_39035	COG3629	intracellular signal transduction
NQK81_39035	COG3903	Transcriptional regulator
NQK81_39045	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NQK81_39055	COG1280	lysine exporter protein (LysE YggA)
NQK81_39065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NQK81_39085	COG1595	DNA-templated transcription, initiation
NQK81_39115	COG1302	Protein conserved in bacteria
NQK81_39125	COG4585	Histidine kinase
NQK81_39130	COG2197	response regulator
NQK81_39135	COG1785	Belongs to the alkaline phosphatase family
NQK81_39270	COG0583	DNA-binding transcription factor activity
NQK81_39275	COG4221	oxidoreductase activity
NQK81_39280	COG2197	response regulator
NQK81_39285	COG4585	Histidine kinase
NQK81_39325	COG2319	Wd-40 repeat
NQK81_39325	COG4249	Peptidase C14 caspase catalytic subunit p20
NQK81_39330	COG1733	regulation of RNA biosynthetic process
NQK81_39350	COG0395	ABC-type sugar transport system, permease component
NQK81_39355	COG1175	transmembrane transport
NQK81_39365	COG1609	Transcriptional regulator
NQK81_39370	COG1472	Belongs to the glycosyl hydrolase 3 family
NQK81_39375	COG4733	cellulase activity
NQK81_39375	COG5297	Belongs to the glycosyl hydrolase family 6
NQK81_39410	COG0598	Magnesium transport protein CorA
NQK81_39430	COG0402	S-adenosylhomocysteine deaminase activity
NQK81_39450	COG3903	Transcriptional regulator
NQK81_39450	COG3629	intracellular signal transduction
NQK81_39465	COG2423	ornithine cyclodeaminase activity
NQK81_39470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NQK81_39475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_39495	COG3903	Transcriptional regulator
NQK81_39495	COG3629	intracellular signal transduction
NQK81_39570	COG1082	Xylose isomerase domain protein TIM barrel
NQK81_39590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NQK81_39605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQK81_39625	COG0745	RESPONSE REGULATOR receiver
NQK81_39630	COG0745	RESPONSE REGULATOR receiver
NQK81_39635	COG0642	Histidine kinase
NQK81_39645	COG0714	Associated with various cellular activities
NQK81_39660	COG2815	serine threonine protein kinase
NQK81_39660	COG0515	serine threonine protein kinase
NQK81_39690	COG0477	Major facilitator Superfamily
NQK81_39700	COG2226	methyltransferase
NQK81_39720	COG1733	regulation of RNA biosynthetic process
NQK81_39725	COG0702	epimerase
NQK81_39740	COG1695	Transcriptional regulator
NQK81_39745	COG0596	Alpha beta hydrolase
NQK81_39795	COG4172	Belongs to the ABC transporter superfamily
NQK81_39800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQK81_39810	COG4166	transmembrane transport
NQK81_39835	COG2271	Major facilitator Superfamily
NQK81_39840	COG4977	sequence-specific DNA binding
NQK81_39865	COG2172	sigma factor antagonist activity
NQK81_39870	COG1366	Belongs to the anti-sigma-factor antagonist family
NQK81_39875	COG1366	Belongs to the anti-sigma-factor antagonist family
NQK81_39900	COG1131	(ABC) transporter
NQK81_39915	COG4829	muconolactone delta-isomerase
NQK81_39920	COG3485	protocatechuate 3,4-dioxygenase
NQK81_39930	COG0583	DNA-binding transcription factor activity
NQK81_39955	COG0444	Belongs to the ABC transporter superfamily
NQK81_39960	COG4608	Belongs to the ABC transporter superfamily
NQK81_39995	COG2197	response regulator
NQK81_40000	COG4585	Histidine kinase
NQK81_40015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQK81_40030	COG0288	reversible hydration of carbon dioxide
NQK81_40070	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_40075	COG1309	transcriptional regulator
NQK81_40080	COG1414	Transcriptional regulator
NQK81_40085	COG3734	2-keto-3-deoxy-galactonokinase
NQK81_40090	COG0800	Aldolase
NQK81_40095	COG4948	Mandelate Racemase Muconate Lactonizing
NQK81_40100	COG2271	Major facilitator Superfamily
NQK81_40110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NQK81_40120	COG1595	DNA-templated transcription, initiation
NQK81_40125	COG0666	response to abiotic stimulus
NQK81_40135	COG4585	Histidine kinase
NQK81_40145	COG0667	Aldo Keto reductase
NQK81_40160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQK81_40165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQK81_40170	COG0798	PFAM Bile acid sodium symporter
NQK81_40175	COG2072	flavoprotein involved in K transport
NQK81_40185	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_40290	COG0583	DNA-binding transcription factor activity
NQK81_40305	COG2197	response regulator
NQK81_40330	COG2197	response regulator
NQK81_40335	COG2197	response regulator
NQK81_40370	COG1131	(ABC) transporter
NQK81_40380	COG2197	response regulator
NQK81_40395	COG2318	DinB family
NQK81_40415	COG0789	Transcriptional regulator
NQK81_40445	COG2124	cytochrome p450
NQK81_40460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NQK81_40465	COG3795	YCII-related domain
NQK81_40470	COG4941	Belongs to the sigma-70 factor family
NQK81_40475	COG1349	DNA-binding transcription factor activity
NQK81_40510	COG3903	Transcriptional regulator
NQK81_40510	COG3629	intracellular signal transduction
NQK81_40515	COG3903	Transcriptional regulator
NQK81_40515	COG3629	intracellular signal transduction
NQK81_40525	COG2197	response regulator
NQK81_40550	COG3237	CsbD-like
NQK81_40580	COG0740	serine-type endopeptidase activity
NQK81_40585	COG0740	serine-type endopeptidase activity
NQK81_40590	COG0515	serine threonine protein kinase
NQK81_40605	COG1902	pentaerythritol trinitrate reductase activity
NQK81_40615	COG1846	Transcriptional regulator
NQK81_40640	COG0559	Belongs to the binding-protein-dependent transport system permease family
NQK81_40695	COG3845	ABC transporter
NQK81_40715	COG1309	transcriptional regulator
NQK81_40750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NQK81_40760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NQK81_40775	COG0583	DNA-binding transcription factor activity
NQK81_40810	COG2066	Belongs to the glutaminase family
NQK81_40830	COG2188	Transcriptional regulator
NQK81_40860	COG0531	amino acid
NQK81_40880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NQK81_40900	COG1175	transmembrane transport
NQK81_40905	COG0395	ABC-type sugar transport system, permease component
NQK81_40910	COG3842	ATPase activity
NQK81_40920	COG1349	DNA-binding transcription factor activity
NQK81_40925	COG1501	Belongs to the glycosyl hydrolase 31 family
NQK81_40930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NQK81_40985	COG0583	DNA-binding transcription factor activity
NQK81_41020	COG1653	transport
NQK81_41035	COG1511	domain protein
NQK81_41055	COG2226	methyltransferase
NQK81_41060	COG0539	negative regulation of cytoplasmic translation
NQK81_41070	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NQK81_41070	COG0237	dephospho-CoA kinase activity
NQK81_41075	COG2197	response regulator
NQK81_41080	COG2203	Gaf domain
NQK81_41080	COG4585	Histidine kinase
NQK81_41115	COG1024	Enoyl-CoA hydratase
NQK81_41130	COG1131	(ABC) transporter
NQK81_41140	COG1506	peptidase
NQK81_41140	COG4946	Tricorn protease homolog
NQK81_41140	COG0823	Involved in the tonB-independent uptake of proteins
NQK81_41155	COG1609	Transcriptional regulator
NQK81_41160	COG1070	Carbohydrate kinase
NQK81_41205	COG3250	beta-galactosidase activity
NQK81_41210	COG3012	SEC-C Motif Domain Protein
NQK81_41310	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NQK81_41325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQK81_41370	COG1733	regulation of RNA biosynthetic process
NQK81_41380	COG1301	dicarboxylic acid transport
NQK81_41385	COG3290	protein histidine kinase activity
NQK81_41390	COG4565	transcriptional regulatory protein
NQK81_41395	COG0789	Transcriptional regulator
NQK81_41430	COG0395	ABC-type sugar transport system, permease component
NQK81_41435	COG1175	transmembrane transport
NQK81_41445	COG2706	6-phosphogluconolactonase activity
NQK81_41450	COG2610	gluconate transmembrane transporter activity
NQK81_41455	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NQK81_41475	COG0251	oxidation-reduction process
NQK81_41480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NQK81_41485	COG1802	Transcriptional regulator
NQK81_41500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NQK81_41505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NQK81_41510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQK81_41515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NQK81_41520	COG0072	phenylalanine-tRNA ligase activity
NQK81_41520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQK81_41555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NQK81_41560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NQK81_41565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NQK81_41570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NQK81_41575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NQK81_41580	COG1438	arginine binding
NQK81_41585	COG0137	argininosuccinate synthase activity
NQK81_41590	COG0165	Argininosuccinate lyase
NQK81_41610	COG2094	Belongs to the DNA glycosylase MPG family
NQK81_41615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NQK81_41640	COG0647	UMP catabolic process
NQK81_41655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NQK81_41680	COG1953	Uracil, thiamine, allantoin
NQK81_41685	COG1802	Transcriptional regulator
NQK81_41695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NQK81_41700	COG0504	CTP synthase activity
NQK81_41705	COG0494	nUDIX hydrolase
NQK81_41735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NQK81_41745	COG2936	dipeptidyl-peptidase activity
NQK81_41750	COG0475	glutathione-regulated potassium exporter activity
NQK81_41780	COG1160	GTP binding
NQK81_41800	COG3321	synthase
NQK81_41800	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_41800	COG0604	alcohol dehydrogenase
NQK81_41805	COG1021	2,3-dihydroxybenzoate-AMP ligase
NQK81_41810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NQK81_41830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQK81_41840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NQK81_41860	COG0154	amidase activity
NQK81_41865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQK81_41870	COG1045	serine acetyltransferase
NQK81_41880	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NQK81_41885	COG0367	asparagine synthase
NQK81_41895	COG1321	iron dependent repressor
NQK81_41905	COG0574	Belongs to the PEP-utilizing enzyme family
NQK81_41905	COG3848	Pyruvate phosphate dikinase
NQK81_41935	COG0154	amidase activity
NQK81_41950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NQK81_41955	COG1414	Transcriptional regulator
NQK81_41965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQK81_41970	COG4948	Mandelate Racemase Muconate Lactonizing
NQK81_41985	COG5492	domain, Protein
NQK81_42000	COG3629	intracellular signal transduction
NQK81_42000	COG3903	Transcriptional regulator
NQK81_42010	COG5001	Diguanylate cyclase
NQK81_42030	COG4981	capsule polysaccharide biosynthetic process
NQK81_42060	COG0500	methyltransferase
NQK81_42090	COG4991	sh3 domain protein
NQK81_42110	COG0596	Alpha beta hydrolase
NQK81_42115	COG3629	intracellular signal transduction
NQK81_42115	COG3903	Transcriptional regulator
NQK81_42130	COG2188	Transcriptional regulator
NQK81_42140	COG1595	DNA-templated transcription, initiation
NQK81_42145	COG1403	HNH endonuclease
NQK81_42150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NQK81_42160	COG0028	Belongs to the TPP enzyme family
NQK81_42165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NQK81_42180	COG2315	Protein conserved in bacteria
NQK81_42185	COG4585	Histidine kinase
NQK81_42190	COG2197	response regulator
NQK81_42195	COG3903	Transcriptional regulator
NQK81_42195	COG3629	intracellular signal transduction
NQK81_42205	COG4106	trans-aconitate 2-methyltransferase activity
NQK81_42230	COG1064	alcohol dehydrogenase
NQK81_42240	COG1309	transcriptional regulator
NQK81_42245	COG1132	(ABC) transporter
NQK81_42265	COG1063	alcohol dehydrogenase
NQK81_42300	COG0477	Major facilitator Superfamily
NQK81_42315	COG1960	acyl-CoA dehydrogenase activity
NQK81_42325	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NQK81_42330	COG2301	Belongs to the HpcH HpaI aldolase family
NQK81_42335	COG1309	transcriptional regulator
NQK81_42345	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_42350	COG2072	flavoprotein involved in K transport
NQK81_42365	COG2197	response regulator
NQK81_42425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQK81_42425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQK81_42445	COG0583	DNA-binding transcription factor activity
NQK81_42460	COG2814	Major facilitator Superfamily
NQK81_42465	COG0583	DNA-binding transcription factor activity
NQK81_42515	COG2318	DinB family
NQK81_42520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NQK81_42520	COG2755	lipolytic protein G-D-S-L family
NQK81_42525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQK81_42540	COG1335	isochorismatase
NQK81_42550	COG3511	phospholipase C
NQK81_42565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NQK81_42570	COG1414	Transcriptional regulator
NQK81_42580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NQK81_42585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NQK81_42595	COG1959	2 iron, 2 sulfur cluster binding
NQK81_42600	COG0702	epimerase
NQK81_42625	COG0667	Aldo Keto reductase
NQK81_42630	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_42635	COG0604	alcohol dehydrogenase
NQK81_42635	COG3321	synthase
NQK81_42680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NQK81_42705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NQK81_42780	COG0515	serine threonine protein kinase
NQK81_42780	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NQK81_42785	COG0515	serine threonine protein kinase
NQK81_42785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NQK81_42810	COG0477	Major facilitator Superfamily
NQK81_42815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NQK81_42815	COG3321	synthase
NQK81_42820	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_42835	COG0300	oxidoreductase activity
NQK81_42840	COG1819	glycosyl
NQK81_42875	COG4251	negative regulation of phosphorylation
NQK81_42880	COG0784	Response regulator, receiver
NQK81_42900	COG0515	serine threonine protein kinase
NQK81_42900	COG2815	serine threonine protein kinase
NQK81_42910	COG0488	(ABC) transporter
NQK81_42925	COG0488	(ABC) transporter
NQK81_42945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NQK81_42955	COG1522	sequence-specific DNA binding
NQK81_43010	COG1733	regulation of RNA biosynthetic process
NQK81_43020	COG0778	Nitroreductase
NQK81_43040	COG2309	aminopeptidase activity
NQK81_43045	COG3473	Maleate cis-trans isomerase
NQK81_43055	COG0477	Major facilitator Superfamily
NQK81_43080	COG1335	isochorismatase
NQK81_43090	COG0686	Belongs to the AlaDH PNT family
NQK81_43095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_43100	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NQK81_43140	COG1414	Transcriptional regulator
NQK81_43150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NQK81_43160	COG2855	membrane
NQK81_43170	COG1113	amino acid transport
NQK81_43175	COG1595	DNA-templated transcription, initiation
NQK81_43185	COG1733	regulation of RNA biosynthetic process
NQK81_43190	COG0427	acetyl-CoA hydrolase
NQK81_43230	COG1609	Transcriptional regulator
NQK81_43240	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_43240	COG0300	oxidoreductase activity
NQK81_43240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NQK81_43240	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_43240	COG3321	synthase
NQK81_43255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NQK81_43290	COG0477	Major facilitator Superfamily
NQK81_43295	COG4221	oxidoreductase activity
NQK81_43320	COG2211	Major facilitator Superfamily
NQK81_43335	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NQK81_43350	COG0583	DNA-binding transcription factor activity
NQK81_43395	COG1174	glycine betaine transport
NQK81_43430	COG2267	carboxylic ester hydrolase activity
NQK81_43440	COG2072	flavoprotein involved in K transport
NQK81_43445	COG0492	ferredoxin-NADP+ reductase activity
NQK81_43470	COG0640	Transcriptional regulator
NQK81_43485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQK81_43490	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NQK81_43500	COG1960	acyl-CoA dehydrogenase activity
NQK81_43530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NQK81_43535	COG2986	histidine ammonia-lyase
NQK81_43550	COG0367	asparagine synthase
NQK81_43570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQK81_43580	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_43595	COG2197	response regulator
NQK81_43635	COG0778	Nitroreductase
NQK81_43640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NQK81_43665	COG1560	Kdo2-lipid A biosynthetic process
NQK81_43670	COG0438	transferase activity, transferring glycosyl groups
NQK81_43680	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NQK81_43680	COG3608	succinylglutamate desuccinylase aspartoacylase
NQK81_43690	COG0277	FAD linked oxidase domain protein
NQK81_43695	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NQK81_43705	COG1770	oligopeptidase
NQK81_43720	COG0367	asparagine synthase
NQK81_43725	COG3629	intracellular signal transduction
NQK81_43725	COG3903	Transcriptional regulator
NQK81_43755	COG1132	(ABC) transporter
NQK81_43760	COG1132	(ABC) transporter
NQK81_43800	COG2226	methyltransferase
NQK81_43805	COG0726	polysaccharide deacetylase
NQK81_43810	COG0277	FAD linked oxidase domain protein
NQK81_43840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NQK81_43890	COG1181	Belongs to the D-alanine--D-alanine ligase family
NQK81_43910	COG1396	sequence-specific DNA binding
NQK81_43925	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NQK81_43930	COG0217	transcriptional regulatory protein
NQK81_43945	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NQK81_43950	COG0632	four-way junction helicase activity
NQK81_43970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQK81_43975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQK81_43980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NQK81_43985	COG1024	Enoyl-CoA hydratase
NQK81_43990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NQK81_43995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQK81_44030	COG3903	Transcriptional regulator
NQK81_44030	COG3629	intracellular signal transduction
NQK81_44080	COG2018	Roadblock/LC7 domain
NQK81_44100	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NQK81_44120	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NQK81_44145	COG1280	lysine exporter protein (LysE YggA)
NQK81_44155	COG2267	carboxylic ester hydrolase activity
NQK81_44165	COG0596	Alpha beta hydrolase
NQK81_44170	COG2223	nitrite transmembrane transporter activity
NQK81_44175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NQK81_44190	COG0045	succinate-CoA ligase (ADP-forming) activity
NQK81_44200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NQK81_44210	COG2223	nitrite transmembrane transporter activity
NQK81_44215	COG1802	Transcriptional regulator
NQK81_44220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NQK81_44225	COG3383	formate dehydrogenase (NAD+) activity
NQK81_44230	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NQK81_44235	COG1034	ATP synthesis coupled electron transport
NQK81_44240	COG3622	Belongs to the hyi family
NQK81_44245	COG2084	Dehydrogenase
NQK81_44250	COG3960	tartronate-semialdehyde synthase activity
NQK81_44270	COG2366	antibiotic biosynthetic process
NQK81_44280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQK81_44300	COG1793	dna ligase
NQK81_44300	COG3285	dna ligase
NQK81_44305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NQK81_44310	COG1522	sequence-specific DNA binding
NQK81_44330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NQK81_44415	COG4977	sequence-specific DNA binding
NQK81_44425	COG2197	response regulator
NQK81_44430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQK81_44435	COG0318	PFAM AMP-dependent synthetase and ligase
NQK81_44440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQK81_44455	COG0302	gtp cyclohydrolase
NQK81_44465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NQK81_44485	COG4106	trans-aconitate 2-methyltransferase activity
NQK81_44500	COG0488	(ABC) transporter
NQK81_44510	COG0395	ABC-type sugar transport system, permease component
NQK81_44530	COG1609	Transcriptional regulator
NQK81_44535	COG1879	ABC-type sugar transport system periplasmic component
NQK81_44545	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQK81_44550	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQK81_44565	COG2160	L-arabinose isomerase activity
NQK81_44570	COG4213	ABC transporter substrate-binding protein
NQK81_44575	COG1129	ABC transporter
NQK81_44580	COG4214	carbohydrate transport
NQK81_44590	COG3940	Belongs to the glycosyl hydrolase 43 family
NQK81_44595	COG3250	beta-galactosidase activity
NQK81_44630	COG3971	2-oxopent-4-enoate hydratase activity
NQK81_44640	COG1012	belongs to the aldehyde dehydrogenase family
NQK81_44655	COG0477	Major facilitator Superfamily
NQK81_44680	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NQK81_44770	COG2409	Drug exporters of the RND superfamily
NQK81_44775	COG1846	Transcriptional regulator
NQK81_44780	COG0702	epimerase
NQK81_44785	COG5297	Belongs to the glycosyl hydrolase family 6
NQK81_44790	COG0745	RESPONSE REGULATOR receiver
NQK81_44795	COG5002	protein histidine kinase activity
NQK81_44805	COG2814	Major facilitator Superfamily
NQK81_44815	COG1733	regulation of RNA biosynthetic process
NQK81_44845	COG1175	transmembrane transport
NQK81_44850	COG0395	ABC-type sugar transport system, permease component
NQK81_44860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NQK81_44875	COG4948	Mandelate Racemase Muconate Lactonizing
NQK81_44880	COG2508	Transcriptional regulator
NQK81_44880	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NQK81_44915	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NQK81_44940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NQK81_44945	COG1028	Short-chain dehydrogenase reductase Sdr
NQK81_44955	COG4638	Rieske (2fe-2S)
NQK81_44985	COG0154	amidase activity
NQK81_44990	COG4566	intracellular signal transduction
NQK81_45000	COG0477	Major facilitator Superfamily
NQK81_45005	COG0154	amidase activity
NQK81_45010	COG1136	(ABC) transporter
NQK81_45010	COG0577	efflux transmembrane transporter activity
NQK81_45040	COG4585	Histidine kinase
NQK81_45045	COG2197	response regulator
NQK81_45065	COG2197	response regulator
NQK81_45070	COG4585	Histidine kinase
NQK81_45075	COG1609	Transcriptional regulator
NQK81_45085	COG1129	ABC transporter
NQK81_45090	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQK81_45095	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQK81_45125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQK81_45160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQK81_45180	COG0508	dehydrogenase complex catalyzes the overall conversion of
NQK81_45200	COG1522	sequence-specific DNA binding
NQK81_45220	COG1940	carbohydrate kinase activity
NQK81_45225	COG2115	Belongs to the xylose isomerase family