locus-tag	class	description
CU254_00045	ENOG4105EVN	Prephenate dehydrogenase
CU254_00050	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CU254_00070	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_00085	ENOG4105K56	Transcriptional regulator
CU254_00120	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
CU254_00135	ENOG4105C0F	tryptophanase EC 4.1.99.1
CU254_00215	ENOG4105CHP	RNA polymerase
CU254_00220	ENOG4108VHT	MarR family transcriptional regulator
CU254_00235	ENOG4107RCI	amp-dependent synthetase and ligase
CU254_00270	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CU254_00275	ENOG41080UQ	Transcriptional regulator
CU254_00295	ENOG4108PBA	serine threonine protein kinase
CU254_00325	ENOG4105EBR	Carboxylesterase
CU254_00415	ENOG4106JDR	secreted
CU254_00440	ENOG4105BZ1	(ABC) transporter
CU254_00565	ENOG4105C59	p-type ATPase
CU254_00570	ENOG4106Z86	ATP-nad acox kinase
CU254_00580	ENOG4105CT1	(ABC) transporter
CU254_00585	ENOG4107Q25	Serine Threonine protein kinase
CU254_00595	ENOG4105CSH	Transporter
CU254_00605	ENOG4105NAF	rna polymerase sigma factor
CU254_00620	ENOG4105VEQ	Cold shock protein
CU254_00660	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
CU254_00665	ENOG4105BZU	Histidine kinase
CU254_00685	ENOG4105C2W	permease
CU254_00725	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CU254_00775	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_00815	ENOG4105K6H	D-cysteine desulfhydrase
CU254_00835	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU254_00840	ENOG4108VW9	Membrane
CU254_00845	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU254_00860	ENOG4106BRA	Membrane
CU254_00885	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CU254_00895	ENOG4105V9F	hemagglutinin
CU254_00910	ENOG4105C84	Histidine ammonia-lyase
CU254_00920	ENOG4105E90	ABC transporter
CU254_00935	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CU254_00965	ENOG4105DQ4	alcohol dehydrogenase
CU254_00995	ENOG4107R4N	Cell wall formation (By similarity)
CU254_01010	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_01015	ENOG4108YZJ	Pfam:DUF2596
CU254_01025	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CU254_01040	ENOG4107S5I	aldo keto reductase
CU254_01045	ENOG4105BZU	Histidine kinase
CU254_01060	ENOG41063NU	Membrane
CU254_01075	ENOG4105II7	pyrroline-5-carboxylate reductase
CU254_01110	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
CU254_01120	ENOG4108AEY	RNA polymerase sigma factor
CU254_01125	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_01145	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CU254_01150	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CU254_01155	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CU254_01180	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CU254_01185	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CU254_01190	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CU254_01205	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CU254_01210	ENOG4108RH7	phosphoglycerate mutase
CU254_01220	ENOG4107QIV	Cytochrome c biogenesis protein
CU254_01230	ENOG4105CRE	cytochrome C
CU254_01250	ENOG4105F7P	transcriptional regulator AsnC family
CU254_01275	ENOG4107SIQ	Naphthoate synthase
CU254_01280	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CU254_01305	ENOG4105ECY	inositol monophosphatase
CU254_01315	ENOG4108MJN	Glycosyl Transferase
CU254_01330	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_01345	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CU254_01350	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CU254_01355	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CU254_01370	ENOG4108IEH	NADH dehydrogenase subunit g
CU254_01375	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CU254_01380	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CU254_01385	ENOG41087XN	oxidoreductase
CU254_01390	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CU254_01395	ENOG4105D65	subunit l
CU254_01405	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CU254_01435	ENOG4105DQU	oxidoreductase, subunit beta
CU254_01440	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
CU254_01450	ENOG4108VVK	transcriptional Regulator, AsnC
CU254_01455	ENOG4105CIK	Amidinotransferase
CU254_01495	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CU254_01540	ENOG4105K64	Glycosyl transferase, family 2
CU254_01560	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_01585	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
CU254_01615	ENOG4107TXC	Transcriptional regulator
CU254_01635	ENOG4108VPT	UPF0234 protein
CU254_01650	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CU254_01655	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CU254_01675	ENOG4105BZU	Histidine kinase
CU254_01690	ENOG4105WDJ	50S ribosomal protein L33
CU254_01695	ENOG410900P	UPF0336 protein
CU254_01710	ENOG4108M8W	Monooxygenase
CU254_01730	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CU254_01735	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CU254_01750	ENOG4108VZM	50s ribosomal protein L10
CU254_01755	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CU254_01825	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CU254_01890	ENOG41085W3	Transposase
CU254_01920	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CU254_01925	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CU254_01930	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CU254_01935	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CU254_01945	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CU254_01950	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CU254_01955	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CU254_01960	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CU254_01965	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CU254_01970	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CU254_01975	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CU254_01980	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CU254_01985	ENOG41082SA	50s ribosomal protein l29
CU254_01990	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CU254_01995	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CU254_02000	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CU254_02005	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CU254_02010	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CU254_02015	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CU254_02020	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CU254_02025	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CU254_02030	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CU254_02035	ENOG410849U	50S ribosomal protein L30
CU254_02040	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CU254_02055	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CU254_02070	ENOG41067V7	50S ribosomal protein L36
CU254_02075	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CU254_02085	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CU254_02090	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CU254_02095	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CU254_02100	ENOG4108ZT0	50S ribosomal protein l17
CU254_02105	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CU254_02150	ENOG4108PZM	peptidase S8 and S53, subtilisin, kexin, sedolisin
CU254_02160	ENOG4105EC2	ftsk spoIIIe
CU254_02165	ENOG4105CFG	Acts as a chaperone (By similarity)
CU254_02195	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CU254_02200	ENOG4108UJD	30S ribosomal protein S9
CU254_02205	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CU254_02240	ENOG4105E98	transcriptional regulator DeoR family
CU254_02250	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU254_02255	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CU254_02260	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
CU254_02265	ENOG4108097	ATP-binding protein
CU254_02275	ENOG4105CGZ	zinc metallopeptidase
CU254_02280	ENOG4105CSH	Transporter
CU254_02285	ENOG4105D8K	carboxyl transferase
CU254_02290	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_02325	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
CU254_02330	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CU254_02365	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CU254_02370	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CU254_02375	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CU254_02380	ENOG4108XFH	Transcriptional regulator
CU254_02385	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
CU254_02420	ENOG4108VT4	
CU254_02435	ENOG4107QVP	Dehydrogenase
CU254_02450	ENOG4105DNP	FAD linked oxidase domain protein
CU254_02475	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CU254_02515	ENOG4105FDR	Membrane
CU254_02520	ENOG4107RSM	transcriptional regulator
CU254_02525	ENOG4108QVN	serine threonine protein kinase
CU254_02530	ENOG4105D9P	serine threonine protein kinase
CU254_02570	ENOG4108K5P	(LipO)protein
CU254_02585	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CU254_02610	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CU254_02625	ENOG41085W3	Transposase
CU254_02640	ENOG4105C0B	DNA polymerase III (alpha subunit)
CU254_02660	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CU254_02670	ENOG4105F27	Major Facilitator
CU254_02675	ENOG4105YVS	arsR family transcriptional regulator
CU254_02680	ENOG4105F27	Major Facilitator
CU254_02710	ENOG4107Y1Y	Methyltransferase
CU254_02735	ENOG4108RQ5	Beta-lactamase domain-containing protein
CU254_02755	ENOG4105C31	Tryptophanyl-tRNA synthetase
CU254_02770	ENOG4107H3J	ribonuclease
CU254_02785	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CU254_02795	ENOG4105E33	succinate dehydrogenase
CU254_02815	ENOG4105DIH	basic membrane
CU254_02820	ENOG4108JQ9	ABC transporter
CU254_02850	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CU254_02855	ENOG4105E5T	Major Facilitator Superfamily
CU254_02860	ENOG4105XEA	Tetr family transcriptional regulator
CU254_02895	ENOG4105CPQ	Dehydrogenase
CU254_02915	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU254_02970	ENOG4105C26	Dehydrogenase
CU254_02975	ENOG4105C26	Dehydrogenase
CU254_02980	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CU254_02995	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CU254_03005	ENOG4108Z4X	TRANSCRIPTIONal
CU254_03010	ENOG4105CPC	Aldo Keto reductase
CU254_03035	ENOG4105ETX	regulatoR
CU254_03050	ENOG4105CPN	adenine deaminase
CU254_03085	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
CU254_03140	ENOG4107RM1	amidohydrolase
CU254_03175	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CU254_03180	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CU254_03185	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CU254_03195	ENOG4105ENE	Histidine kinase
CU254_03210	ENOG4108JIK	carboxylase
CU254_03230	ENOG4107WR6	Maf-like protein
CU254_03255	ENOG4108SGK	Tetr family transcriptional regulator
CU254_03270	ENOG4105D8K	carboxyl transferase
CU254_03295	ENOG4105ECQ	AraC Family Transcriptional Regulator
CU254_03305	ENOG4105FBN	Acid phosphatase
CU254_03325	ENOG4105K4H	Nlp p60 protein
CU254_03330	ENOG4108EKN	Biotin protein ligase C terminal domain
CU254_03340	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CU254_03360	ENOG4107TK4	histidinol-phosphate phosphatase
CU254_03365	ENOG4105ETX	regulatoR
CU254_03370	ENOG41065SU	Two-component system sensor kinase
CU254_03415	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CU254_03420	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_03475	ENOG4107TB5	TRANSCRIPTIONal
CU254_03480	ENOG4107TB5	TRANSCRIPTIONal
CU254_03500	ENOG4108TJN	glycosyl transferase group 1
CU254_03565	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CU254_03580	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
CU254_03585	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
CU254_03600	ENOG4108Z4U	Ferredoxin
CU254_03615	ENOG4107SCK	Monooxygenase
CU254_03635	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
CU254_03660	ENOG4108URH	decarboxylase
CU254_03670	ENOG4105C3Q	Glycosyl transferase, family 2
CU254_03680	ENOG4105IDI	abc transporter atp-binding protein
CU254_03685	ENOG4108JJ9	ABC, transporter
CU254_03690	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CU254_03695	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CU254_03720	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CU254_03725	ENOG4105CGU	Enoyl-CoA hydratase
CU254_03735	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CU254_03745	ENOG4108KXM	LysR family Transcriptional regulator
CU254_03750	ENOG4105D94	Major Facilitator Superfamily
CU254_03755	ENOG4107ZBN	O-methyltransferase
CU254_03775	ENOG4105C0H	protease
CU254_03780	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CU254_03800	ENOG4105CJW	magnesium transporter
CU254_03825	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_03870	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CU254_03885	ENOG4105D7N	magnesium and cobalt transport protein CorA
CU254_03915	ENOG4105DB7	PHP domain protein
CU254_03920	ENOG41081FY	multiple antibiotic resistance (MarC)-related
CU254_03940	ENOG4105C1J	atp-dependent rna helicase
CU254_03970	ENOG410832A	alpha/beta hydrolase fold
CU254_04015	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CU254_04020	ENOG4108IFG	nitrite reductase, (NAD(P)H)
CU254_04025	ENOG4107QND	Nitrite extrusion protein
CU254_04030	ENOG4107QZF	nitrite reductase NADPH large subunit
CU254_04035	ENOG4107QZF	nitrite reductase NADPH large subunit
CU254_04065	ENOG4105D29	Helix-turn-helix type 11 domain protein
CU254_04080	ENOG4105DQ6	Transposase
CU254_04130	ENOG4108WQ6	secreted protein
CU254_04135	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CU254_04170	ENOG4105C1V	Peptidase, M16
CU254_04180	ENOG4105EVU	fructokinase
CU254_04190	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
CU254_04195	ENOG4105DRS	transport system, permease
CU254_04200	ENOG4105F8D	glycoside hydrolase family 4
CU254_04215	ENOG4105NPE	arsR family transcriptional regulator
CU254_04220	ENOG4105C6Z	Gluconate
CU254_04225	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CU254_04255	ENOG4105EGD	dinuclear metal center protein, YbgI family
CU254_04265	ENOG4105CVJ	phosphoglycerate mutase
CU254_04275	ENOG4107R5R	arsenical pump membrane protein
CU254_04280	ENOG4105FBW	Monooxygenase
CU254_04340	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CU254_04345	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CU254_04375	ENOG4105C26	Dehydrogenase
CU254_04380	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU254_04385	ENOG4107TYH	extracellular solute-binding protein family 1
CU254_04390	ENOG4105D81	ABC transporter, permease
CU254_04395	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
CU254_04400	ENOG4108HGY	Proline imino-peptidase
CU254_04410	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CU254_04420	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CU254_04425	ENOG4105CRK	lysyL-tRNA synthetase
CU254_04445	ENOG4105C4K	Nad synthetase
CU254_04450	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CU254_04470	ENOG4105C5F	glutamine synthetase
CU254_04475	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_04505	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CU254_04515	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CU254_04530	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
CU254_04535	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
CU254_04540	ENOG4105C7W	Xanthine dehydrogenase
CU254_04590	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CU254_04650	ENOG4108IXY	short-chain dehydrogenase reductase
CU254_04655	ENOG4108IG5	Transcriptional regulator
CU254_04690	ENOG4108IMY	Transcriptional regulator
CU254_04695	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CU254_04700	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CU254_04710	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
CU254_04720	ENOG41082BM	Transcriptional regulator, arsr family
CU254_04760	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
CU254_04810	ENOG41063PX	domain protein
CU254_04820	ENOG4105DJZ	UPF0182 protein
CU254_04840	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CU254_04845	ENOG4105CAK	Cell division ATP-binding protein ftsE
CU254_04850	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
CU254_04855	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CU254_04875	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_04880	ENOG4105ENE	Histidine kinase
CU254_04900	ENOG4105DMQ	Methyltransferase
CU254_04920	ENOG4105C84	Histidine ammonia-lyase
CU254_04925	ENOG4105CGP	Urocanate hydratase
CU254_04935	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CU254_04940	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU254_04945	ENOG4105CN2	monooxygenase, FAD-binding
CU254_04970	ENOG4105BZU	Histidine kinase
CU254_04975	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_04995	ENOG4105CJ1	ABC, transporter
CU254_05000	ENOG4105CQ7	ATP-dependent helicase
CU254_05005	ENOG4107UBR	Extracellular solute-binding protein family 3
CU254_05025	ENOG4105ZXU	NLP P60 protein
CU254_05040	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU254_05040	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU254_05045	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU254_05055	ENOG4108UZX	fmn reductase
CU254_05085	ENOG41062B0	ABC transporter, permease
CU254_05090	ENOG4107R9N	ABC transporter
CU254_05095	ENOG4105C2J	ABC transporter
CU254_05100	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
CU254_05105	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_05140	ENOG41085W3	Transposase
CU254_05180	ENOG4107T8T	UPF0173 metal-dependent hydrolase
CU254_05185	ENOG4105IK6	Terpene synthase metal-binding domain-containing protein
CU254_05195	ENOG4105CNT	hydrolase family 2
CU254_05200	ENOG4105DRS	transport system, permease
CU254_05215	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_05245	ENOG4105BZU	Histidine kinase
CU254_05265	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CU254_05280	ENOG4105C54	Major Facilitator superfamily
CU254_05300	ENOG410905P	Pyridoxamine 5-phosphate
CU254_05305	ENOG4108YYC	ycei family
CU254_05315	ENOG4105CHF	Glutathione S-transferase
CU254_05320	ENOG4105CIR	epoxide hydrolase
CU254_05355	ENOG4108Z7F	N-acetyltransferase
CU254_05360	ENOG4108JCI	Transcriptional regulator
CU254_05370	ENOG4105DQE	DNA ligase
CU254_05380	ENOG4107VWK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CU254_05390	ENOG41068WN	
CU254_05395	ENOG4108222	arsenate reductase
CU254_05425	ENOG4105BZU	Histidine kinase
CU254_05470	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CU254_05485	ENOG4107QX9	Thiol disulfide interChange protein
CU254_05490	ENOG4105BZU	Histidine kinase
CU254_05495	ENOG4105F0K	SARP family transcriptional regulator
CU254_05550	ENOG4107JC6	Membrane
CU254_05575	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CU254_05580	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CU254_05585	ENOG4105WBV	Transcriptional regulator
CU254_05595	ENOG4105DY8	decarboxylase
CU254_05600	ENOG4105F27	Major Facilitator
CU254_05605	ENOG4105CV8	reductase
CU254_05620	ENOG4105EKT	)-iron permease
CU254_05625	ENOG4105DBE	peroxidase
CU254_05665	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
CU254_05675	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CU254_05710	ENOG4105F44	Two component transcriptional regulator, winged helix family
CU254_05715	ENOG4106F60	Histidine kinase
CU254_05720	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CU254_05725	ENOG4108UQS	dipeptidase
CU254_05730	ENOG4105CPF	Cell wall formation (By similarity)
CU254_05760	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_05765	ENOG4105BZU	Histidine kinase
CU254_05795	ENOG4105CGD	Nad-dependent epimerase dehydratase
CU254_05820	ENOG4106A3M	Cytochrome p-450
CU254_05840	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CU254_05855	ENOG4107RCI	amp-dependent synthetase and ligase
CU254_05875	ENOG4105C84	Histidine ammonia-lyase
CU254_05885	ENOG4105DTI	Phosphonopyruvate decarboxylase
CU254_05925	ENOG4105EGE	secreted protein
CU254_05965	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
CU254_06000	ENOG4105E89	ABC transporter
CU254_06005	ENOG4108HW4	amino acid AbC transporter
CU254_06010	ENOG4105CDA	abc transporter atp-binding protein
CU254_06025	ENOG4108M15	ABC transporter
CU254_06030	ENOG4105KCT	ABC transporter
CU254_06060	ENOG41085W3	Transposase
CU254_06095	ENOG4105D4B	ABC, transporter
CU254_06135	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CU254_06150	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CU254_06160	ENOG4105VEQ	Cold shock protein
CU254_06165	ENOG4105C1J	atp-dependent rna helicase
CU254_06185	ENOG4105BZM	domain protein
CU254_06195	ENOG4105F95	Monooxygenase
CU254_06215	ENOG4105F27	Major Facilitator
CU254_06230	ENOG4105CSH	Transporter
CU254_06235	ENOG4105CH2	amidohydrolase
CU254_06245	ENOG4105ECQ	AraC Family Transcriptional Regulator
CU254_06260	ENOG4108IG5	Transcriptional regulator
CU254_06275	ENOG4105DXM	phenylacetic acid degradation protein
CU254_06280	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
CU254_06285	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
CU254_06290	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
CU254_06295	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
CU254_06300	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CU254_06315	ENOG4108QER	Adenylate cyclase
CU254_06350	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_06375	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CU254_06380	ENOG4105CR4	methylisocitrate lyase
CU254_06385	ENOG4107QN1	sodium solute
CU254_06405	ENOG4108NEV	two component transcriptional regulator, LytTR family
CU254_06410	ENOG4108HRK	Histidine kinase
CU254_06415	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CU254_06425	ENOG4105C2J	ABC transporter
CU254_06435	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_06440	ENOG4105CWX	Alpha-1,2-mannosidase
CU254_06445	ENOG4105CWX	Alpha-1,2-mannosidase
CU254_06455	ENOG41067TZ	transcriptional regulator, MarR family
CU254_06480	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CU254_06500	ENOG4105DKW	ABC transporter
CU254_06505	ENOG4105UPE	Enoyl-CoA hydratase
CU254_06510	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_06525	ENOG4108NNZ	chitinase
CU254_06530	ENOG4105NAE	bifunctional deaminase-reductase domain protein
CU254_06545	ENOG4108JU3	Alkyl hydroperoxide reductase
CU254_06565	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
CU254_06580	ENOG4108X07	Tetr family transcriptional regulator
CU254_06585	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CU254_06600	ENOG410630P	Transcriptional regulator
CU254_06620	ENOG4105ZXU	NLP P60 protein
CU254_06630	ENOG4105EVB	acetyltransferase
CU254_06655	ENOG4107R9S	Malate synthase
CU254_06660	ENOG4105KPY	Small multidrug resistance protein
CU254_06670	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CU254_06690	ENOG4108V06	Glutathione peroxidase
CU254_06700	ENOG4108KQJ	Type 11 methyltransferase
CU254_06710	ENOG4105EPR	degv family
CU254_06720	ENOG4105C10	Electron transfer flavoprotein
CU254_06750	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CU254_06765	ENOG4105C5X	domain protein
CU254_06785	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CU254_06805	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CU254_06810	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_06815	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CU254_06840	ENOG4105C01	Dihydroxy-acid dehydratase
CU254_06855	ENOG4108ZP8	Acetolactate synthase small subunit
CU254_06860	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CU254_06890	ENOG4108Z6Z	Transcriptional regulator
CU254_06925	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
CU254_06930	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CU254_06935	ENOG4105EHG	Permease protein
CU254_06940	ENOG4105E0A	ABC, transporter
CU254_06950	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CU254_06955	ENOG4105ERH	Fumarylacetoacetate hydrolase
CU254_07000	ENOG4107SQ8	Glycine betaine
CU254_07005	ENOG4108IJ7	Glycine betaine
CU254_07020	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CU254_07025	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CU254_07030	ENOG4105K70	DNA-binding protein
CU254_07045	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
CU254_07055	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CU254_07065	ENOG4107RB3	L-asparaginase
CU254_07080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU254_07085	ENOG4105BZU	Histidine kinase
CU254_07095	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU254_07105	ENOG4105CPF	Cell wall formation (By similarity)
CU254_07110	ENOG41079KZ	Major Facilitator Superfamily
CU254_07135	ENOG4108Z0R	Transferase
CU254_07140	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CU254_07150	ENOG4105DQ6	Transposase
CU254_07155	ENOG4105VB9	50S ribosomal protein l28
CU254_07160	ENOG4105DP4	dak2 domain fusion protein ylov
CU254_07190	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CU254_07195	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CU254_07295	ENOG4105DEN	Luciferase family
CU254_07300	ENOG4105EEM	helicase
CU254_07305	ENOG4106H78	methyltransferase
CU254_07310	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CU254_07335	ENOG41084BZ	50S ribosomal protein L32
CU254_07340	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CU254_07345	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CU254_07370	ENOG4108Z86	Glutamine amidotransferase
CU254_07375	ENOG4105C26	Dehydrogenase
CU254_07385	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CU254_07390	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CU254_07395	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CU254_07400	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CU254_07405	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CU254_07410	ENOG4105EJQ	L-serine dehydratase
CU254_07420	ENOG41073TP	transcriptional regulator
CU254_07425	ENOG4105BZ4	penicillin-binding protein
CU254_07430	ENOG4105E0A	ABC, transporter
CU254_07435	ENOG4107SQD	Transcriptional regulator, GntR family
CU254_07440	ENOG4105PDP	Short chain dehydrogenase
CU254_07450	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
CU254_07455	ENOG4105C2C	drug resistance transporter, Bcr CflA
CU254_07460	ENOG4105ERH	Fumarylacetoacetate hydrolase
CU254_07465	ENOG4105DIA	mandelate racemase muconate lactonizing
CU254_07480	ENOG4105C2J	ABC transporter
CU254_07495	ENOG4105JXH	GntR family transcriptional regulator
CU254_07530	ENOG4105BZW	Glycerate kinase
CU254_07550	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_07560	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
CU254_07565	ENOG4105F2Z	3-oxoadipate enol-lactonase
CU254_07570	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
CU254_07575	ENOG4107HP6	Transcriptional regulator
CU254_07580	ENOG41080QG	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CU254_07620	ENOG4105BZU	Histidine kinase
CU254_07625	ENOG4105CAY	ferredoxin--nadp reductase
CU254_07650	ENOG4105C2J	ABC transporter
CU254_07655	ENOG4105CNN	ABC, transporter
CU254_07660	ENOG4105D4B	ABC, transporter
CU254_07665	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
CU254_07670	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_07675	ENOG4105CK5	oxidoreductase
CU254_07685	ENOG4105CHR	reductase
CU254_07695	ENOG4105CAQ	asparagine synthetase
CU254_07705	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CU254_07710	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CU254_07715	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CU254_07735	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
CU254_07755	ENOG4107RJ1	sodium solute
CU254_07760	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CU254_07775	ENOG41069M3	Transcriptional regulator
CU254_07780	ENOG4107R9S	Malate synthase
CU254_07795	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CU254_07800	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CU254_07815	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CU254_07820	ENOG4105J7D	transcriptional regulator
CU254_07825	ENOG4105C2W	permease
CU254_07880	ENOG4105JQZ	Methyltransferase
CU254_07890	ENOG4105K4P	CoA-binding domain protein
CU254_07920	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CU254_07940	ENOG4105BZ1	(ABC) transporter
CU254_07965	ENOG4105K5M	30s ribosomal protein S16
CU254_07975	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CU254_07985	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CU254_07990	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CU254_07995	ENOG4107QYR	Signal peptidase i
CU254_08000	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CU254_08010	ENOG41080R2	UPF0102 protein
CU254_08015	ENOG4105C0P	Mg chelatase subunit ChlI
CU254_08030	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU254_08035	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CU254_08045	ENOG4105CE9	30S ribosomal protein S2
CU254_08050	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CU254_08055	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CU254_08060	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CU254_08075	ENOG41089UC	methyltransferase, type 11
CU254_08090	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CU254_08095	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_08130	ENOG4105EA8	2-Nitropropane dioxygenase
CU254_08150	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CU254_08195	ENOG4105DHT	Metal Dependent Phosphohydrolase
CU254_08225	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CU254_08235	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CU254_08265	ENOG4105CQB	FAD linked oxidase domain protein
CU254_08270	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CU254_08280	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CU254_08285	ENOG4108YYH	Nadph-dependent fmn reductase
CU254_08295	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
CU254_08305	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CU254_08315	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CU254_08355	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
CU254_08365	ENOG4105EX0	alpha-galactosidase
CU254_08370	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CU254_08380	ENOG41073TP	transcriptional regulator
CU254_08385	ENOG4105DJ2	Major Facilitator Superfamily
CU254_08405	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CU254_08415	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CU254_08420	ENOG4105C1J	atp-dependent rna helicase
CU254_08430	ENOG4105CPC	Aldo Keto reductase
CU254_08440	ENOG4107XFJ	UPF0246 protein
CU254_08455	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CU254_08465	ENOG4105FF5	Membrane
CU254_08480	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_08500	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CU254_08510	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU254_08525	ENOG4107QN2	dihydrolipoyl dehydrogenase
CU254_08560	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CU254_08575	ENOG4108IUX	(ABC) transporter
CU254_08580	ENOG4105RHA	ABC transporter, permease
CU254_08605	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CU254_08625	ENOG4105C92	Aminotransferase class V
CU254_08635	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CU254_08660	ENOG4105C0B	DNA polymerase III (alpha subunit)
CU254_08700	ENOG4108NRW	Phospholipase, patatin family
CU254_08710	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CU254_08735	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CU254_08745	ENOG4105ECP	epimerase
CU254_08760	ENOG4105F9F	transposase
CU254_08795	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CU254_08815	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CU254_08825	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CU254_08830	ENOG4105CPC	Aldo Keto reductase
CU254_08860	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CU254_08865	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
CU254_08880	ENOG4107S1N	anthranilate phosphoribosyltransferase
CU254_08895	ENOG4105CCU	oxidase (Subunit III)
CU254_08900	ENOG4107UDY	cytochrome C
CU254_08910	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CU254_08950	ENOG4105JNK	Glycosyl transferase (Group 1
CU254_08965	ENOG4106A3M	Cytochrome p-450
CU254_08970	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CU254_08975	ENOG4105CHH	sulfate transporter
CU254_08980	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CU254_08990	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CU254_09000	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CU254_09005	ENOG4108IYU	L-aspartate oxidase
CU254_09015	ENOG41090GG	peptidase S8 and S53, subtilisin, kexin, sedolisin
CU254_09085	ENOG4105EC2	ftsk spoIIIe
CU254_09130	ENOG4105ECQ	AraC Family Transcriptional Regulator
CU254_09140	ENOG4108Z4X	TRANSCRIPTIONal
CU254_09160	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_09165	ENOG4108S01	response regulator
CU254_09175	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CU254_09180	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CU254_09185	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CU254_09195	ENOG4108RQ5	Beta-lactamase domain-containing protein
CU254_09205	ENOG4105EYF	MMPL domain protein
CU254_09210	ENOG4108IG5	Transcriptional regulator
CU254_09215	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CU254_09225	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
CU254_09230	ENOG4108Z4X	TRANSCRIPTIONal
CU254_09250	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CU254_09255	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CU254_09300	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CU254_09305	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CU254_09320	ENOG4105CRQ	synthase (Component I)
CU254_09330	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CU254_09335	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CU254_09340	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CU254_09370	ENOG4105CH2	amidohydrolase
CU254_09375	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CU254_09395	ENOG4105CBC	glutamate synthase
CU254_09410	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CU254_09425	ENOG4105DZ6	Band 7 protein
CU254_09530	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CU254_09535	ENOG4107QRT	dEAD DEAH box helicase
CU254_09545	ENOG4105CFG	Acts as a chaperone (By similarity)
CU254_09555	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CU254_09560	ENOG4105KC9	Modulates RecA activity (By similarity)
CU254_09565	ENOG4108UHU	Aldolase
CU254_09570	ENOG4105C01	Dihydroxy-acid dehydratase
CU254_09590	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CU254_09650	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CU254_09665	ENOG4105DRP	amino acid AbC transporter
CU254_09670	ENOG4108Q1T	ABC transporter
CU254_09675	ENOG4107UBR	Extracellular solute-binding protein family 3
CU254_09680	ENOG4105CDA	abc transporter atp-binding protein
CU254_09690	ENOG4105DHQ	Histidine kinase
CU254_09705	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CU254_09715	ENOG4105C99	atpase involved in dna repair
CU254_09720	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CU254_09725	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CU254_09730	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CU254_09745	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CU254_09755	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CU254_09770	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CU254_09775	ENOG4107Z3H	Transcriptional regulator, TetR family
CU254_09845	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
CU254_09850	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_09855	ENOG4105BZU	Histidine kinase
CU254_09870	ENOG4105CMR	udp-glucose 4-epimerase
CU254_09875	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CU254_09885	ENOG4105KHC	sulfurtransferase
CU254_09895	ENOG4105DGU	Histone deacetylase
CU254_09905	ENOG4108KC2	acyl-Coa dehydrogenase
CU254_09910	ENOG4105X7H	acyl-CoA dehydrogenase
CU254_09920	ENOG4105CHR	reductase
CU254_10005	ENOG4105XT2	Transcriptional regulator
CU254_10010	ENOG41061H0	Monooxygenase
CU254_10015	ENOG41082VC	UPF0145 protein
CU254_10040	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
CU254_10050	ENOG4105DKQ	ROK family
CU254_10060	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CU254_10065	ENOG4105YIP	Tetr family transcriptional regulator
CU254_10075	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
CU254_10090	ENOG4105E9Q	Acyl-transferase
CU254_10105	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CU254_10145	ENOG41082YX	Transcriptional regulator, arsr family
CU254_10165	ENOG4105C29	acyl-CoA thioesterase
CU254_10185	ENOG4107SM8	Adenylate Guanylate cyclase
CU254_10195	ENOG4105W1N	transcriptional regulator
CU254_10200	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_10205	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CU254_10225	ENOG4105XM7	Lipoprotein lprD
CU254_10235	ENOG4107QN1	sodium solute
CU254_10250	ENOG4105GWZ	Roadblock lc7 family protein
CU254_10285	ENOG4105D5P	Methylmalonyl-coA mutase
CU254_10295	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CU254_10300	ENOG4105D2B	acyl-CoA dehydrogenase
CU254_10305	ENOG4108SGK	Tetr family transcriptional regulator
CU254_10330	ENOG4105CHR	reductase
CU254_10350	ENOG4105EUJ	GTP cyclohydrolase i
CU254_10385	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CU254_10390	ENOG4108RK3	acyl-Coa dehydrogenase
CU254_10395	ENOG4105X7H	acyl-CoA dehydrogenase
CU254_10400	ENOG410900P	UPF0336 protein
CU254_10425	ENOG4105DTN	riboflavin biosynthesis protein ribF
CU254_10450	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
CU254_10460	ENOG4108KC1	acyl-Coa dehydrogenase
CU254_10465	ENOG41088PD	hydrolase
CU254_10470	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU254_10475	ENOG4105MXW	flavin reductase domain protein, FMN-binding
CU254_10490	ENOG41061H0	Monooxygenase
CU254_10510	ENOG4106KE4	Dehydrogenase
CU254_10520	ENOG4105E1V	na solute symporter
CU254_10535	ENOG4108VQT	Alpha beta hydrolase fold protein
CU254_10550	ENOG4105F2C	Acetyl-CoA acetyltransferase
CU254_10555	ENOG4106A3M	Cytochrome p-450
CU254_10565	ENOG4107H3J	ribonuclease
CU254_10575	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_10590	ENOG4105E39	Enoyl-CoA hydratase
CU254_10615	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CU254_10625	ENOG4105FDP	GntR family transcriptional regulator
CU254_10635	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CU254_10640	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
CU254_10650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU254_10660	ENOG4108N53	binding-protein-dependent transport systems inner membrane Component
CU254_10680	ENOG4107GFK	fumarate
CU254_10690	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CU254_10695	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CU254_10710	ENOG4105D7K	pfkb domain protein
CU254_10715	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
CU254_10745	ENOG4105DFW	ABC transporter
CU254_10750	ENOG4105C2J	ABC transporter
CU254_10755	ENOG4108HWW	ABC transporter
CU254_10775	ENOG4105C5F	glutamine synthetase
CU254_10790	ENOG4108RYK	Nad-dependent epimerase dehydratase
CU254_10795	ENOG4105CUB	amino acid
CU254_10805	ENOG4105BZU	Histidine kinase
CU254_10860	ENOG4105DFK	Polyphosphate glucokinase
CU254_10885	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CU254_10915	ENOG4107VEG	TrkA-N domain protein
CU254_10920	ENOG4105C0X	amino acid
CU254_10925	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CU254_10945	ENOG4105C26	Dehydrogenase
CU254_10950	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CU254_10975	ENOG4105C26	Dehydrogenase
CU254_11005	ENOG4105F44	Two component transcriptional regulator, winged helix family
CU254_11010	ENOG4106F60	Histidine kinase
CU254_11030	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU254_11035	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_11045	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU254_11055	ENOG41069M3	Transcriptional regulator
CU254_11065	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_11075	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CU254_11085	ENOG4107JTW	chlorite dismutase
CU254_11090	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
CU254_11105	ENOG4105E18	UPF0276 protein
CU254_11125	ENOG4105E0X	reductase
CU254_11145	ENOG4105DQE	DNA ligase
CU254_11155	ENOG4105DEN	Luciferase family
CU254_11165	ENOG4108K8K	Transcriptional regulator
CU254_11170	ENOG4105C26	Dehydrogenase
CU254_11180	ENOG41080RH	Thioredoxin
CU254_11250	ENOG4105C8Y	Acetylornithine aminotransferase
CU254_11255	ENOG4105CSR	polyphosphate kinase 2
CU254_11275	ENOG4105C9M	aspartyl-trna synthetase
CU254_11310	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CU254_11330	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CU254_11345	ENOG4105E2X	shikimate dehydrogenase
CU254_11350	ENOG4105RHY	Pfam:UPF0157
CU254_11370	ENOG410849S	phosphocarrier protein (HPr)
CU254_11375	ENOG4105CI1	PTS System
CU254_11380	ENOG4105FDP	GntR family transcriptional regulator
CU254_11385	ENOG4105CI1	PTS System
CU254_11420	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CU254_11425	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CU254_11430	ENOG4105D49	3-dehydroquinate synthase
CU254_11435	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CU254_11455	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CU254_11460	ENOG410803B	Involved in the transcription termination process (By similarity)
CU254_11470	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CU254_11475	ENOG4105CXT	aspartate transcarbamylase
CU254_11490	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CU254_11500	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
CU254_11510	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CU254_11515	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CU254_11525	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CU254_11555	ENOG4105EYW	Ion transport protein
CU254_11570	ENOG4105KTH	gatB Yqey
CU254_11575	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CU254_11605	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CU254_11610	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CU254_11625	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CU254_11630	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CU254_11635	ENOG4105CHW	UPF0052 protein
CU254_11640	ENOG4105CIE	May be required for sporulation (By similarity)
CU254_11645	ENOG4105DEN	Luciferase family
CU254_11680	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CU254_11685	ENOG4105BZA	Phosphoglycerate kinase
CU254_11690	ENOG4105CP7	Triose-phosphate isomerase
CU254_11705	ENOG4105BZU	Histidine kinase
CU254_11715	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
CU254_11730	ENOG4105C89	phosphohexose isomerase
CU254_11735	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CU254_11745	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CU254_11760	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CU254_11785	ENOG4107VFP	cytochrome oxidase assembly
CU254_11795	ENOG4105CJ1	ABC, transporter
CU254_11800	ENOG4107JC6	Membrane
CU254_11830	ENOG4108UNV	SUF system FeS assembly protein, NifU family
CU254_11835	ENOG4105VG1	fes assembly suf system protein
CU254_11850	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CU254_11860	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_11865	ENOG4105BZU	Histidine kinase
CU254_11870	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_11875	ENOG4105BZU	Histidine kinase
CU254_11880	ENOG4108JT6	LycopEne
CU254_11905	ENOG4105C5H	ABC transporter
CU254_11920	ENOG4105BZ1	(ABC) transporter
CU254_11935	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CU254_11940	ENOG4108KGH	TRANSCRIPTIONal
CU254_11980	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CU254_11985	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CU254_11995	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CU254_12000	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CU254_12025	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_12030	ENOG4107QX3	carboxylase
CU254_12055	ENOG4106UDK	Cellulose-binding, family II
CU254_12080	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CU254_12110	ENOG4105CJA	serine threonine protein kinase
CU254_12130	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CU254_12135	ENOG4106T9R	serine protease
CU254_12140	ENOG4107V9H	nitrite transporter
CU254_12180	ENOG4108ZT1	Transcriptional regulator
CU254_12185	ENOG4105C26	Dehydrogenase
CU254_12220	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
CU254_12230	ENOG4105CHR	reductase
CU254_12235	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CU254_12240	ENOG4105C7K	acetolactate synthase
CU254_12250	ENOG41079KZ	Major Facilitator Superfamily
CU254_12310	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CU254_12330	ENOG4105EFA	4-hydroxyphenylacetate
CU254_12405	ENOG4105E7W	lamb ycsf family protein
CU254_12415	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CU254_12460	ENOG4105HHS	UPF0256 protein
CU254_12470	ENOG4105C7W	Xanthine dehydrogenase
CU254_12500	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
CU254_12505	ENOG4108ZGX	Histidine kinase
CU254_12510	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_12545	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CU254_12565	ENOG4105CPQ	Dehydrogenase
CU254_12575	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_12580	ENOG4105EU0	Major facilitator Superfamily
CU254_12650	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CU254_12745	ENOG4105C0F	tryptophanase EC 4.1.99.1
CU254_12765	ENOG4105C6F	GntR Family Transcriptional Regulator
CU254_12795	ENOG4105CHR	reductase
CU254_12800	ENOG4105JXH	GntR family transcriptional regulator
CU254_12810	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_12820	ENOG4105C3U	ABC transporter
CU254_12855	ENOG4105CPP	Dehydrogenase, E1 component
CU254_12860	ENOG4107RUY	(E1 component), alpha subunit
CU254_12865	ENOG4108M9J	MaoC like domain protein
CU254_12875	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_12905	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
CU254_12915	ENOG4108VQT	Alpha beta hydrolase fold protein
CU254_12945	ENOG4108HUF	Transporter
CU254_12955	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_12985	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
CU254_12990	ENOG4105DQ5	transport system permease protein
CU254_12995	ENOG4105TVJ	transport system, permease
CU254_13010	ENOG4105CHR	reductase
CU254_13020	ENOG4105CSH	Transporter
CU254_13025	ENOG4106UDK	Cellulose-binding, family II
CU254_13030	ENOG4105RHY	Pfam:UPF0157
CU254_13035	ENOG4105D2B	acyl-CoA dehydrogenase
CU254_13040	ENOG4105D2B	acyl-CoA dehydrogenase
CU254_13045	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_13070	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CU254_13080	ENOG4107QHQ	amino acid
CU254_13130	ENOG4105D3G	Pseudouridine synthase
CU254_13140	ENOG4105K56	Transcriptional regulator
CU254_13150	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CU254_13230	ENOG4105DJ2	Major Facilitator Superfamily
CU254_13240	ENOG4105YIP	Tetr family transcriptional regulator
CU254_13250	ENOG4107RGD	Major Facilitator superfamily
CU254_13265	ENOG4105C0B	DNA polymerase III (alpha subunit)
CU254_13275	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CU254_13280	ENOG4105C2J	ABC transporter
CU254_13285	ENOG4105CNN	ABC, transporter
CU254_13290	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CU254_13305	ENOG4105KF0	sporulation and cell division protein, SsgA
CU254_13315	ENOG4105CV8	reductase
CU254_13320	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_13340	ENOG4105C3R	Methionine synthase
CU254_13345	ENOG4105CBC	glutamate synthase
CU254_13370	ENOG4105BZ4	penicillin-binding protein
CU254_13380	ENOG4105CJ1	ABC, transporter
CU254_13410	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CU254_13415	ENOG4107QPH	glycogen) synthase
CU254_13420	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CU254_13435	ENOG4105FDP	GntR family transcriptional regulator
CU254_13455	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CU254_13460	ENOG4108JQ7	(ABC) transporter
CU254_13465	ENOG4105C3U	ABC transporter
CU254_13475	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_13480	ENOG41073TP	transcriptional regulator
CU254_13495	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CU254_13515	ENOG41065SU	Two-component system sensor kinase
CU254_13520	ENOG4108KXV	response regulator
CU254_13530	ENOG4105CHP	RNA polymerase
CU254_13535	ENOG4105GRZ	Ycii-related protein
CU254_13580	ENOG4108IG5	Transcriptional regulator
CU254_13625	ENOG4105DK2	UPF0207 protein
CU254_13665	ENOG4106A3M	Cytochrome p-450
CU254_13670	ENOG4105PF9	Transcriptional regulator
CU254_13675	ENOG4105DQ6	Transposase
CU254_13695	ENOG4105CIF	Ornithine Cyclodeaminase
CU254_13700	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CU254_13710	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CU254_13725	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CU254_13735	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CU254_13740	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
CU254_13755	ENOG4105CHP	RNA polymerase
CU254_13775	ENOG4105FDP	GntR family transcriptional regulator
CU254_13795	ENOG4105C5H	ABC transporter
CU254_13800	ENOG4105CH6	catalase
CU254_13835	ENOG4108KXM	LysR family Transcriptional regulator
CU254_13840	ENOG4107AQZ	Membrane
CU254_13870	ENOG4105KBX	Transcriptional regulator, TetR family
CU254_13890	ENOG4106NZI	LysR family Transcriptional regulator
CU254_13895	ENOG410605W	Major Facilitator
CU254_13900	ENOG4107SVN	transposase
CU254_13920	ENOG4105EWU	Squalene--hopene cyclase
CU254_13930	ENOG4105CVN	desaturase
CU254_13940	ENOG4105FBD	synthase
CU254_13950	ENOG4108W6C	Dehydrogenase
CU254_13960	ENOG4105PP6	Membrane
CU254_13975	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CU254_13980	ENOG4107RSM	transcriptional regulator
CU254_13990	ENOG4105DKW	ABC transporter
CU254_14010	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
CU254_14015	ENOG4105J76	Periplasmic binding protein
CU254_14020	ENOG4105E0A	ABC, transporter
CU254_14035	ENOG4105EAB	amino acid AbC transporter
CU254_14040	ENOG4105CDA	abc transporter atp-binding protein
CU254_14050	ENOG4105QE3	oxidoreductase
CU254_14055	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CU254_14085	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CU254_14100	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_14125	ENOG4105CHR	reductase
CU254_14130	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CU254_14150	ENOG4105CWX	Alpha-1,2-mannosidase
CU254_14155	ENOG4105C2C	drug resistance transporter, Bcr CflA
CU254_14160	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CU254_14230	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
CU254_14305	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CU254_14325	ENOG4105D29	Helix-turn-helix type 11 domain protein
CU254_14365	ENOG4105XDV	
CU254_14430	ENOG4105E4F	Isochorismate synthase
CU254_14475	ENOG4105EA8	2-Nitropropane dioxygenase
CU254_14480	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_14485	ENOG4108VUG	Enoyl-CoA hydratase
CU254_14495	ENOG4105E39	Enoyl-CoA hydratase
CU254_14500	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
CU254_14510	ENOG4105CSP	Major Facilitator Superfamily
CU254_14520	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_14540	ENOG4105CSH	Transporter
CU254_14555	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_14565	ENOG4105C57	major facilitator superfamily
CU254_14570	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CU254_14575	ENOG4105DH8	myo-inositol catabolism
CU254_14590	ENOG4105FDP	GntR family transcriptional regulator
CU254_14600	ENOG4108M9J	MaoC like domain protein
CU254_14610	ENOG4105CQB	FAD linked oxidase domain protein
CU254_14615	ENOG41073TP	transcriptional regulator
CU254_14630	ENOG4107RF2	cellulose-binding family II protein
CU254_14750	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_14885	ENOG4105BZU	Histidine kinase
CU254_14905	ENOG4105CIR	epoxide hydrolase
CU254_14910	ENOG4105QPS	Monooxygenase
CU254_14940	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_14960	ENOG4105C26	Dehydrogenase
CU254_14965	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CU254_14975	ENOG4105F38	ABC transporter, permease
CU254_14980	ENOG4105D38	putrescine abc transporter
CU254_14985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU254_14995	ENOG4107XWI	flavin reductase domain protein, FMN-binding
CU254_15055	ENOG4105Y3U	Transglycosylase-associated protein
CU254_15060	ENOG4108KPJ	rna polymerase sigma factor
CU254_15065	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_15090	ENOG4107SCK	Monooxygenase
CU254_15105	ENOG4105MHT	Transcriptional regulator, ARSR family
CU254_15115	ENOG41072TH	Protein of unknown function (DUF1479)
CU254_15130	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_15140	ENOG4105C26	Dehydrogenase
CU254_15145	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CU254_15175	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CU254_15185	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CU254_15205	ENOG4105CSH	Transporter
CU254_15250	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU254_15280	ENOG41073TP	transcriptional regulator
CU254_15285	ENOG4105CHR	reductase
CU254_15295	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_15300	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_15305	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_15315	ENOG4105CC9	acyl-Coa dehydrogenase
CU254_15320	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_15325	ENOG4105D2B	acyl-CoA dehydrogenase
CU254_15335	ENOG4105X7H	acyl-CoA dehydrogenase
CU254_15350	ENOG4107WEA	mandelate racemase muconate lactonizing
CU254_15355	ENOG4105C0A	alcohol dehydrogenase
CU254_15360	ENOG4107QTZ	amino acid
CU254_15405	ENOG4105C0X	amino acid
CU254_15435	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CU254_15440	ENOG4105CQB	FAD linked oxidase domain protein
CU254_15445	ENOG4105DIA	mandelate racemase muconate lactonizing
CU254_15455	ENOG4105BZP	glycoside hydrolase 15-related
CU254_15465	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CU254_15470	ENOG4105FDF	Could be involved in DNA repair (By similarity)
CU254_15480	ENOG4105CJ3	phosphate transporter
CU254_15490	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
CU254_15560	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CU254_15570	ENOG4105C0X	amino acid
CU254_15635	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CU254_15650	ENOG4108NBA	ATP-dependent carboxylate-amine ligase (By similarity)
CU254_15655	ENOG4108TKH	Nitroreductase
CU254_15660	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CU254_15690	ENOG4105KVH	Transcriptional regulator
CU254_15700	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CU254_15715	ENOG4105MSY	salicylate hydroxylase
CU254_15720	ENOG41079KZ	Major Facilitator Superfamily
CU254_15745	ENOG4108UAU	isochorismatase
CU254_15815	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_15845	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CU254_15850	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CU254_15855	ENOG4106517	Short-chain dehydrogenase reductase Sdr
CU254_15865	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CU254_15890	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CU254_15895	ENOG4105DKP	glycosyl transferase, family 9
CU254_15900	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CU254_15925	ENOG41082SX	arsR family transcriptional regulator
CU254_15940	ENOG4105EFZ	amidohydrolase
CU254_15950	ENOG4108UQS	dipeptidase
CU254_15975	ENOG4107RSM	transcriptional regulator
CU254_16030	ENOG4105DQ6	Transposase
CU254_16040	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CU254_16050	ENOG4105ESN	nucleotide-binding protein
CU254_16055	ENOG4105ESN	nucleotide-binding protein
CU254_16065	ENOG4108PA7	Methyltransferase
CU254_16075	ENOG4107S5I	aldo keto reductase
CU254_16135	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_16145	ENOG4107Y80	Major Facilitator superfamily
CU254_16165	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
CU254_16205	ENOG4105CJW	magnesium transporter
CU254_16245	ENOG4105EBR	Carboxylesterase
CU254_16255	ENOG4105KVH	Transcriptional regulator
CU254_16265	ENOG4105M4P	Tetr family transcriptional regulator
CU254_16275	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CU254_16305	ENOG4105CJA	serine threonine protein kinase
CU254_16310	ENOG4105DUM	transcriptional regulator, lysR family
CU254_16330	ENOG4105F8D	glycoside hydrolase family 4
CU254_16335	ENOG4108RVA	ribokinase
CU254_16340	ENOG4105DRS	transport system, permease
CU254_16355	ENOG4105DDC	Oxidoreductase domain protein
CU254_16360	ENOG4105MVE	transcriptional regulator
CU254_16365	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CU254_16375	ENOG4105D2N	Aldolase
CU254_16395	ENOG4105DZC	cytosine deaminase
CU254_16400	ENOG4105DRR	Transcriptional regulator, GntR family
CU254_16405	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU254_16410	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU254_16415	ENOG4105E1V	na solute symporter
CU254_16435	ENOG4105CHR	reductase
CU254_16450	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_16455	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_16460	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU254_16470	ENOG4108JQ7	(ABC) transporter
CU254_16490	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
CU254_16500	ENOG4105EW9	transcriptional regulator AsnC family
CU254_16540	ENOG4107R7Y	intracellular protease Pfpi family
CU254_16580	ENOG4107S1Q	Phosphatase
CU254_16605	ENOG41088SP	formiminoglutamate hydrolase
CU254_16610	ENOG4105E5Q	amino acid AbC transporter
CU254_16625	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CU254_16665	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
CU254_16700	ENOG4105CG3	alpha amylase, catalytic region
CU254_16720	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_16745	ENOG4108M8W	Monooxygenase
CU254_16750	ENOG4105EXC	Acyl-transferase
CU254_16810	ENOG4105EE1	crotonyl-CoA reductase
CU254_16815	ENOG4105FS7	Transcriptional regulator
CU254_16850	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_16860	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_16870	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_16935	ENOG4105MXW	flavin reductase domain protein, FMN-binding
CU254_16940	ENOG4107HP6	Transcriptional regulator
CU254_16970	ENOG4107SCK	Monooxygenase
CU254_17020	ENOG4105ECQ	AraC Family Transcriptional Regulator
CU254_17025	ENOG4105CIR	epoxide hydrolase
CU254_17030	ENOG4105DJ2	Major Facilitator Superfamily
CU254_17065	ENOG4105F2Z	3-oxoadipate enol-lactonase
CU254_17095	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CU254_17135	ENOG4105E1F	short-chain dehydrogenase reductase
CU254_17140	ENOG4105C01	Dihydroxy-acid dehydratase
CU254_17155	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
CU254_17160	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
CU254_17170	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_17210	ENOG410616I	blue (type 1) copper domain protein
CU254_17250	ENOG4105CHR	reductase
CU254_17275	ENOG4107YPT	transcriptional regulator
CU254_17300	ENOG41079KZ	Major Facilitator Superfamily
CU254_17315	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU254_17340	ENOG4105NPE	arsR family transcriptional regulator
CU254_17355	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CU254_17375	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CU254_17390	ENOG4105C9B	Cysteine desulfurase
CU254_17395	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_17405	ENOG4105C3R	Methionine synthase
CU254_17415	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CU254_17470	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_17510	ENOG4105E6M	Sulphatase-modifying factor protein
CU254_17570	ENOG4105C85	amino acid
CU254_17575	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CU254_17585	ENOG4108FUF	Transcriptional regulator, IclR family
CU254_17615	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU254_17620	ENOG4105DCF	alanine dehydrogenase
CU254_17625	ENOG4107WUY	phosphate acetyltransferase
CU254_17650	ENOG4106KR7	LysR family Transcriptional regulator
CU254_17675	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
CU254_17685	ENOG4105CPU	Monooxygenase
CU254_17690	ENOG4105CPU	Monooxygenase
CU254_17715	ENOG4108JQ6	ABC transporter
CU254_17720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_17730	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_17740	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CU254_17755	ENOG4107ZXU	DSBA oxidoreductase
CU254_17765	ENOG4107QYR	Signal peptidase i
CU254_17775	ENOG4105C74	pyruvyl transferase
CU254_17780	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_17790	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_17800	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU254_17810	ENOG4108SHN	Glycosyl transferase, family 2
CU254_17820	ENOG4105DK2	UPF0207 protein
CU254_17825	ENOG41069FZ	L,D-transpeptidase catalytic domain
CU254_17840	ENOG4105DVW	rieske (2Fe-2S)
CU254_17885	ENOG4105CV8	reductase
CU254_17900	ENOG4107UAX	integral membrane protein
CU254_17940	ENOG4105DUM	transcriptional regulator, lysR family
CU254_17945	ENOG4105D1K	glutamate--cysteine ligase
CU254_17950	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
CU254_17955	ENOG4108V75	Glutamine amidotransferase
CU254_17960	ENOG41067HS	methyltransferase
CU254_17980	ENOG410650H	(LipO)protein
CU254_17985	ENOG4105DBE	peroxidase
CU254_17995	ENOG4105DQ6	Transposase
CU254_18000	ENOG4107QM5	aconitate hydratase
CU254_18005	ENOG4105ZXU	NLP P60 protein
CU254_18020	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CU254_18030	ENOG4107QVM	von Willebrand factor, type A
CU254_18045	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CU254_18060	ENOG41062D9	Histidine kinase
CU254_18070	ENOG4105CSH	Transporter
CU254_18080	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CU254_18095	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CU254_18105	ENOG4105EET	magnesium chelatase
CU254_18110	ENOG4107KWJ	von Willebrand factor, type A
CU254_18115	ENOG4107TXC	Transcriptional regulator
CU254_18120	ENOG4105C8N	cysteinyl-tRNA synthetase
CU254_18140	ENOG4107Y80	Major Facilitator superfamily
CU254_18160	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
CU254_18165	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
CU254_18170	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CU254_18175	ENOG4107QJE	Chromosome Partitioning Protein
CU254_18210	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
CU254_18235	ENOG4105PTV	Nudix Hydrolase
CU254_18240	ENOG4105E5F	proteasome
CU254_18245	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
CU254_18250	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
CU254_18255	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
CU254_18260	ENOG4105CHP	RNA polymerase
CU254_18265	ENOG4105GRZ	Ycii-related protein
CU254_18280	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
CU254_18315	ENOG4105CBD	Diacylglycerol kinase
CU254_18355	ENOG4105J0Q	Transcriptional regulator
CU254_18385	ENOG4105CHP	RNA polymerase
CU254_18395	ENOG4105EMU	Dehydrogenase
CU254_18400	ENOG4105E1F	short-chain dehydrogenase reductase
CU254_18425	ENOG4105EGE	secreted protein
CU254_18460	ENOG4105C2C	drug resistance transporter, Bcr CflA
CU254_18475	ENOG4105CPC	Aldo Keto reductase
CU254_18480	ENOG4105CPQ	Dehydrogenase
CU254_18485	ENOG4105EFZ	amidohydrolase
CU254_18515	ENOG4105C3U	ABC transporter
CU254_18520	ENOG4108JQ6	ABC transporter
CU254_18550	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_18580	ENOG4108J9M	Transporter
CU254_18585	ENOG4105CMQ	Chloride channel
CU254_18590	ENOG4105BZU	Histidine kinase
CU254_18595	ENOG4108KXV	response regulator
CU254_18600	ENOG4107W7X	Aldolase
CU254_18605	ENOG4108KEZ	Dehydrogenase
CU254_18625	ENOG4107HP6	Transcriptional regulator
CU254_18665	ENOG4105C54	Major Facilitator superfamily
CU254_18675	ENOG4108RZE	Tetr family transcriptional regulator
CU254_18680	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
CU254_18690	ENOG4106HB6	Alpha beta hydrolase
CU254_18695	ENOG4105IYB	L-carnitine dehydratase bile acid-inducible protein F
CU254_18700	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_18705	ENOG4108M9J	MaoC like domain protein
CU254_18715	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_18725	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_18735	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_18800	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CU254_18805	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CU254_18815	ENOG41062D9	Histidine kinase
CU254_18850	ENOG4105CSH	Transporter
CU254_18855	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_18870	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CU254_18875	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
CU254_18910	ENOG4105C26	Dehydrogenase
CU254_18925	ENOG4105EG6	Saccharopine dehydrogenase
CU254_18955	ENOG4105CD3	dihydroorotase
CU254_18965	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CU254_18975	ENOG4105MHT	Transcriptional regulator, ARSR family
CU254_18990	ENOG4107RSM	transcriptional regulator
CU254_19005	ENOG4107W53	thymidine kinase
CU254_19035	ENOG4108Z6Z	Transcriptional regulator
CU254_19045	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU254_19060	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CU254_19065	ENOG4108SGK	Tetr family transcriptional regulator
CU254_19070	ENOG4105CSU	acyl-Coa dehydrogenase
CU254_19075	ENOG4105DHI	Methyltransferase
CU254_19090	ENOG4105ERH	Fumarylacetoacetate hydrolase
CU254_19095	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
CU254_19115	ENOG4105C0D	helicase
CU254_19130	ENOG4108VQT	Alpha beta hydrolase fold protein
CU254_19135	ENOG4105GRZ	Ycii-related protein
CU254_19160	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
CU254_19180	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU254_19195	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CU254_19225	ENOG4108IND	Tetr family transcriptional regulator
CU254_19230	ENOG4105DDN	Pentapeptide repeat-containing protein
CU254_19355	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU254_19370	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_19375	ENOG4105D9G	High-affinity
CU254_19430	ENOG4105CSH	Transporter
CU254_19450	ENOG4105CPC	Aldo Keto reductase
CU254_19470	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CU254_19475	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
CU254_19500	ENOG41090CE	integral membrane protein
CU254_19510	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_19515	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU254_19530	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CU254_19550	ENOG4105CWX	Alpha-1,2-mannosidase
CU254_19570	ENOG4105CPC	Aldo Keto reductase
CU254_19585	ENOG4105FS7	Transcriptional regulator
CU254_19595	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CU254_19630	ENOG4108NNZ	chitinase
CU254_19635	ENOG4105DJB	Major Facilitator Superfamily
CU254_19640	ENOG4105DGW	oligopeptidase A
CU254_19650	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CU254_19655	ENOG4105CPC	Aldo Keto reductase
CU254_19670	ENOG4105CHP	RNA polymerase
CU254_19715	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
CU254_19720	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
CU254_19730	ENOG4107QSI	ABC, transporter
CU254_19735	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU254_19740	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_19785	ENOG4105DQE	DNA ligase
CU254_19800	ENOG4105J1Z	Arabinosyltransferase
CU254_19805	ENOG4105C85	amino acid
CU254_19855	ENOG4105EMU	Dehydrogenase
CU254_19875	ENOG41060W2	glyoxylate carboligase
CU254_19880	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CU254_19885	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
CU254_19895	ENOG4105EZE	Cupin 4 family protein
CU254_19905	ENOG4108WYP	Transcriptional regulator
CU254_19910	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CU254_19915	ENOG4107R37	Glutamate dehydrogenase
CU254_19925	ENOG4105DNP	FAD linked oxidase domain protein
CU254_19940	ENOG4106NZI	LysR family Transcriptional regulator
CU254_19955	ENOG4105E33	succinate dehydrogenase
CU254_19970	ENOG4105C26	Dehydrogenase
CU254_19985	ENOG4105CR8	Transcriptional regulator
CU254_19990	ENOG4105H3G	oxidoreductase
CU254_20010	ENOG4108IJ0	Aspartate ammonia-lyase
CU254_20015	ENOG4105CSH	Transporter
CU254_20020	ENOG410839U	amino acid
CU254_20045	ENOG4108JQ6	ABC transporter
CU254_20050	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_20060	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_20075	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_20115	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CU254_20150	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CU254_20180	ENOG4108XET	gCN5-related N-acetyltransferase
CU254_20185	ENOG4105CPQ	Dehydrogenase
CU254_20195	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
CU254_20200	ENOG4105C5Q	Transcriptional regulator
CU254_20205	ENOG4105ECR	NmrA family
CU254_20245	ENOG4108UW8	fha domain-containing protein
CU254_20275	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CU254_20280	ENOG4105E39	Enoyl-CoA hydratase
CU254_20290	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CU254_20295	ENOG4108IND	Tetr family transcriptional regulator
CU254_20300	ENOG4107W19	lmbE family
CU254_20305	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CU254_20310	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CU254_20315	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CU254_20320	ENOG4105W0E	50S ribosomal protein L33
CU254_20325	ENOG4105KDC	50s ribosomal protein l28
CU254_20335	ENOG4105NRA	50s ribosomal protein l31 type b
CU254_20340	ENOG4108BT0	50S ribosomal protein L32
CU254_20345	ENOG4105CKI	cobalamin synthesis protein
CU254_20355	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CU254_20370	ENOG4105CT4	transporter
CU254_20375	ENOG4105DYW	oxidoreductase
CU254_20400	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
CU254_20410	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU254_20440	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CU254_20450	ENOG4105E2Y	ABC, transporter
CU254_20455	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CU254_20465	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CU254_20480	ENOG4105BZ1	(ABC) transporter
CU254_20485	ENOG4105BZ1	(ABC) transporter
CU254_20505	ENOG4105C5H	ABC transporter
CU254_20515	ENOG4105E39	Enoyl-CoA hydratase
CU254_20550	ENOG4105XTG	Pfam:DUF156
CU254_20565	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_20580	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CU254_20655	ENOG4108JPW	Aminotransferase
CU254_20665	ENOG4108FUF	Transcriptional regulator, IclR family
CU254_20670	ENOG4107R0V	Pyruvate dehydrogenase
CU254_20675	ENOG4105CPP	Dehydrogenase, E1 component
CU254_20680	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
CU254_20685	ENOG4105CSH	Transporter
CU254_20710	ENOG4105F27	Major Facilitator
CU254_20735	ENOG4108I5G	Major Facilitator superfamily
CU254_20765	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CU254_20785	ENOG4105CHR	reductase
CU254_20835	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_20860	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CU254_20870	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_20900	ENOG4108RVA	ribokinase
CU254_20910	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CU254_20915	ENOG4105CI0	Citrate lyase
CU254_20935	ENOG4107U32	Beta-lactamase domain protein
CU254_20940	ENOG4107SVN	transposase
CU254_20950	ENOG4105CB2	alcohol dehydrogenase
CU254_20980	ENOG4105KVH	Transcriptional regulator
CU254_20990	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
CU254_20995	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CU254_21015	ENOG4107XEY	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CU254_21020	ENOG4108KPJ	rna polymerase sigma factor
CU254_21035	ENOG4107UB2	Alpha beta hydrolase fold
CU254_21045	ENOG4105MC2	DSBA oxidoreductase
CU254_21050	ENOG41082SX	arsR family transcriptional regulator
CU254_21055	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CU254_21075	ENOG4105D2S	major facilitator superfamily
CU254_21085	ENOG4105FP9	thiamine pyrophosphate
CU254_21110	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
CU254_21115	ENOG4106URE	pyrroloquinoline quinone biosynthesis protein d
CU254_21125	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
CU254_21170	ENOG4105CNT	hydrolase family 2
CU254_21180	ENOG4105U3E	Transcriptional regulator
CU254_21185	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CU254_21240	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CU254_21255	ENOG4105DQE	DNA ligase
CU254_21320	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CU254_21335	ENOG4105D9P	serine threonine protein kinase
CU254_21360	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CU254_21370	ENOG4105FDF	Could be involved in DNA repair (By similarity)
CU254_21395	ENOG4105C7K	acetolactate synthase
CU254_21435	ENOG4105C5X	domain protein
CU254_21470	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CU254_21475	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CU254_21480	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CU254_21490	ENOG4105ZCJ	preprotein translocase subunit yajC
CU254_21495	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CU254_21500	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CU254_21505	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CU254_21520	ENOG4105CDY	transcriptional regulatory protein
CU254_21525	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
CU254_21530	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
CU254_21545	ENOG4105D2S	major facilitator superfamily
CU254_21565	ENOG4107W6X	Transcriptional regulator
CU254_21570	ENOG4105DYW	oxidoreductase
CU254_21595	ENOG41061H0	Monooxygenase
CU254_21605	ENOG4108IMY	Transcriptional regulator
CU254_21630	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
CU254_21640	ENOG4105E2K	Glycosyl transferase (Group 1
CU254_21645	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
CU254_21650	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
CU254_21655	ENOG41090MY	MarR family Transcriptional regulator
CU254_21665	ENOG4105C22	threonyL-tRNA synthetase
CU254_21670	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
CU254_21675	ENOG4105D3Q	Sugar transferase
CU254_21695	ENOG4105F0K	SARP family transcriptional regulator
CU254_21700	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CU254_21710	ENOG4106A3M	Cytochrome p-450
CU254_21720	ENOG4105CHR	reductase
CU254_21725	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CU254_21730	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CU254_21765	ENOG4108JA1	polyketide synthase
CU254_21770	ENOG4107EEY	synthase
CU254_21785	ENOG4106A3M	Cytochrome p-450
CU254_21800	ENOG4105KF0	sporulation and cell division protein, SsgA
CU254_21825	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CU254_21845	ENOG4105JSC	dimethylmenaquinone methyltransferase
CU254_21865	ENOG4108IXY	short-chain dehydrogenase reductase
CU254_21885	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CU254_21910	ENOG41083YR	Protein CrcB homolog
CU254_21915	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU254_21925	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CU254_21940	ENOG4105C01	Dihydroxy-acid dehydratase
CU254_21945	ENOG4108VIA	integral membrane protein
CU254_21960	ENOG4105GTG	Isochorismatase
CU254_21970	ENOG4105E1F	short-chain dehydrogenase reductase
CU254_21985	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CU254_21995	ENOG4105CG3	alpha amylase, catalytic region
CU254_22000	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
CU254_22010	ENOG4105D29	Helix-turn-helix type 11 domain protein
CU254_22055	ENOG4107QPD	alcohol dehydrogenase
CU254_22065	ENOG4108WYP	Transcriptional regulator
CU254_22120	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CU254_22150	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
CU254_22160	ENOG4105DEG	Vwa containing coxe family protein
CU254_22175	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CU254_22185	ENOG4106AM8	polysaccharide lyase family 8
CU254_22200	ENOG4105EQX	glucarate dehydratase
CU254_22205	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
CU254_22210	ENOG4106P37	HTH-type transcriptional regulator YjhI
CU254_22215	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CU254_22265	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CU254_22270	ENOG4107RIS	Acyl-transferase
CU254_22275	ENOG4105CAT	Cytidine monophosphate kinase
CU254_22290	ENOG4107S91	Sodium hydrogen exchanger
CU254_22305	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CU254_22310	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CU254_22335	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CU254_22340	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CU254_22350	ENOG4105DRR	Transcriptional regulator, GntR family
CU254_22355	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CU254_22395	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CU254_22410	ENOG4105DSU	hydrolase
CU254_22435	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CU254_22440	ENOG4108VX5	3-methyladenine DNA glycosylase
CU254_22445	ENOG4105CH7	arginosuccinase
CU254_22450	ENOG4105CDH	Citrulline--aspartate ligase
CU254_22455	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
CU254_22460	ENOG4105DBV	ornithine carbamoyltransferase
CU254_22465	ENOG4105C8Y	Acetylornithine aminotransferase
CU254_22470	ENOG4105CAS	nag kinase
CU254_22475	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CU254_22480	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CU254_22500	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CU254_22505	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CU254_22510	ENOG4108RWN	rrna methyltransferase
CU254_22515	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CU254_22520	ENOG41084BS	50S ribosomal protein L35
CU254_22545	ENOG4105KME	endoribonuclease L-psp
CU254_22570	ENOG4105C6Z	Gluconate
CU254_22575	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CU254_22595	ENOG4105E2D	ec 3.2.1.52
CU254_22600	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CU254_22605	ENOG4108MRH	transcriptional regulatory protein
CU254_22610	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CU254_22615	ENOG4105CK2	sodium dicarboxylate symporter
CU254_22620	ENOG4105KVH	Transcriptional regulator
CU254_22645	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CU254_22660	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CU254_22680	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CU254_22690	ENOG4105K5B	UPF0225 protein
CU254_22700	ENOG4105EBR	Carboxylesterase
CU254_22705	ENOG4105EEQ	Na H antiporter
CU254_22710	ENOG4105GCF	PGAM
CU254_22735	ENOG4105CMG	Carbohydrate kinase
CU254_22740	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_22755	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CU254_22760	ENOG4105DU1	integral membrane protein, terc
CU254_22765	ENOG4105CJ1	ABC, transporter
CU254_22775	ENOG41060WC	Enoyl-CoA hydratase
CU254_22810	ENOG4105CJ1	ABC, transporter
CU254_22840	ENOG4105C22	threonyL-tRNA synthetase
CU254_22845	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CU254_22865	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CU254_22870	ENOG4105DMQ	Methyltransferase
CU254_22885	ENOG4105ECB	domain protein
CU254_22905	ENOG4108IV0	ABC, transporter
CU254_22910	ENOG4105C0Z	ABC transporter
CU254_22915	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CU254_22920	ENOG4105C32	Amino acid ABC transporter (Permease)
CU254_22925	ENOG4105CP9	extracellular ligand-binding receptor
CU254_22975	ENOG4105BZU	Histidine kinase
CU254_22995	ENOG4107SVN	transposase
CU254_23000	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
CU254_23010	ENOG4105KT7	mgtC SapB transporter
CU254_23025	ENOG41061ZR	Transcriptional regulator
CU254_23035	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CU254_23075	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CU254_23080	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CU254_23110	ENOG4105E1F	short-chain dehydrogenase reductase
CU254_23115	ENOG4105EYF	MMPL domain protein
CU254_23120	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_23125	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CU254_23190	ENOG4108UAJ	Transcriptional regulator
CU254_23205	ENOG4105BZU	Histidine kinase
CU254_23230	ENOG4108FUF	Transcriptional regulator, IclR family
CU254_23245	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CU254_23265	ENOG4107SM8	Adenylate Guanylate cyclase
CU254_23275	ENOG4107SET	aldo keto reductase
CU254_23290	ENOG4105KMT	branched-chain amino acid
CU254_23295	ENOG4108UMN	azlc family
CU254_23300	ENOG4105F7P	transcriptional regulator AsnC family
CU254_23315	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_23370	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CU254_23415	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
CU254_23430	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
CU254_23440	ENOG4105MXW	flavin reductase domain protein, FMN-binding
CU254_23450	ENOG4107S2E	monooxygenase
CU254_23455	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU254_23485	ENOG4107258	Transcriptional regulator
CU254_23490	ENOG4105CHR	reductase
CU254_23500	ENOG4105CHR	reductase
CU254_23510	ENOG4108UDB	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
CU254_23525	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CU254_23535	ENOG41082JN	Transcriptional regulator
CU254_23540	ENOG4105EE1	crotonyl-CoA reductase
CU254_23545	ENOG41069M3	Transcriptional regulator
CU254_23550	ENOG4105CQB	FAD linked oxidase domain protein
CU254_23555	ENOG4108JB8	alcohol dehydrogenase
CU254_23560	ENOG4105CSH	Transporter
CU254_23585	ENOG41074CX	linocin_m18 bacteriocin protein
CU254_23610	ENOG4105QAX	Iron-sulfur
CU254_23615	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CU254_23620	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CU254_23625	ENOG4105EM7	Selenocysteine-specific translation elongation factor
CU254_23630	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
CU254_23640	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CU254_23675	ENOG4107R4Z	monovalent cation h antiporter subunit d
CU254_23685	ENOG4105RFA	Lsr2-like protein
CU254_23720	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
CU254_23765	ENOG4105PGM	cation diffusion facilitator family transporter
CU254_23770	ENOG4105DR5	peptidase
CU254_23810	ENOG4107ZR7	Membrane
CU254_23825	ENOG4105CPU	Monooxygenase
CU254_23830	ENOG4105DEN	Luciferase family
CU254_23865	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CU254_23870	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CU254_23875	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CU254_23905	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CU254_23910	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_23920	ENOG4105CHR	reductase
CU254_23925	ENOG4105E39	Enoyl-CoA hydratase
CU254_23930	ENOG4105EA8	2-Nitropropane dioxygenase
CU254_23935	ENOG4105F2C	Acetyl-CoA acetyltransferase
CU254_23945	ENOG4105CC9	acyl-Coa dehydrogenase
CU254_23955	ENOG4105D2B	acyl-CoA dehydrogenase
CU254_23960	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_23965	ENOG4105D2B	acyl-CoA dehydrogenase
CU254_23985	ENOG4108RZE	Tetr family transcriptional regulator
CU254_23990	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_24000	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_24010	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CU254_24020	ENOG4105CHR	reductase
CU254_24030	ENOG4108QIU	Dehydrogenase
CU254_24035	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CU254_24045	ENOG4105DXX	methyltransferase
CU254_24055	ENOG4106NZI	LysR family Transcriptional regulator
CU254_24085	ENOG4105E2Z	phosphate ABC transporter (Permease
CU254_24095	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CU254_24100	ENOG4108Z18	K06886 hemoglobin
CU254_24150	ENOG4105FUY	alpha subunit
CU254_24155	ENOG4107RSM	transcriptional regulator
CU254_24160	ENOG4105DTQ	mandelate racemase muconate lactonizing
CU254_24165	ENOG4108QMY	dioxygenase
CU254_24175	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU254_24180	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU254_24205	ENOG4105D2B	acyl-CoA dehydrogenase
CU254_24210	ENOG4105CC9	acyl-Coa dehydrogenase
CU254_24240	ENOG4108KB2	LysR family Transcriptional regulator
CU254_24285	ENOG4105EUB	pirin domain protein
CU254_24295	ENOG4108KXV	response regulator
CU254_24300	ENOG41065SU	Two-component system sensor kinase
CU254_24315	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CU254_24325	ENOG4108Z4X	TRANSCRIPTIONal
CU254_24340	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CU254_24355	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CU254_24370	ENOG4105CPC	Aldo Keto reductase
CU254_24375	ENOG4105M6F	mutator MutT protein
CU254_24395	ENOG4105E2R	ROK family
CU254_24420	ENOG4105DYW	oxidoreductase
CU254_24460	ENOG4105C9B	Cysteine desulfurase
CU254_24465	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CU254_24470	ENOG4108ZHR	arsR family transcriptional regulator
CU254_24475	ENOG4105CJN	penicillin-binding protein
CU254_24480	ENOG4105C85	amino acid
CU254_24485	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CU254_24505	ENOG4108ZHR	arsR family transcriptional regulator
CU254_24525	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CU254_24530	ENOG4105DFA	alanine racemase domain protein
CU254_24535	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CU254_24550	ENOG4105K6V	RNA polymerase
CU254_24565	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CU254_24600	ENOG4105ME9	cell division protein FtsQ
CU254_24605	ENOG4105DFU	Cell wall formation (By similarity)
CU254_24620	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CU254_24625	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CU254_24645	ENOG4105CJN	penicillin-binding protein
CU254_24655	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CU254_24660	ENOG4108V6E	Cell division protein mraZ
CU254_24685	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CU254_24705	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CU254_24715	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CU254_24720	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
CU254_24735	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CU254_24755	ENOG4105WBV	Transcriptional regulator
CU254_24760	ENOG4105CEV	competence damage-inducible protein
CU254_24770	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CU254_24775	ENOG4106F1P	AAA ATPase, central domain protein
CU254_24780	ENOG4105EXC	Acyl-transferase
CU254_24795	ENOG4107QZI	cell division protein FtsK
CU254_24810	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CU254_24820	ENOG4105CN5	Metallo-Beta-Lactamase
CU254_24825	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CU254_24845	ENOG4107SMJ	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
CU254_24870	ENOG4105T0Z	Conserved Protein
CU254_24895	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CU254_24900	ENOG4105C1V	Peptidase, M16
CU254_24905	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CU254_24910	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CU254_24915	ENOG4108784	2'-5' rna ligase
CU254_24930	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CU254_24940	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CU254_24955	ENOG4105SFS	phosphoesterase RecJ domain protein
CU254_24970	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CU254_24980	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CU254_24995	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
CU254_25030	ENOG4105BZU	Histidine kinase
CU254_25035	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_25070	ENOG4105GVJ	transcriptional regulator
CU254_25095	ENOG4105D6N	CoA-transferase, subunit a
CU254_25105	ENOG4105KVH	Transcriptional regulator
CU254_25115	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU254_25120	ENOG4105BZU	Histidine kinase
CU254_25125	ENOG4107TB5	TRANSCRIPTIONal
CU254_25150	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
CU254_25160	ENOG4107NQ8	LysR family Transcriptional regulator
CU254_25165	ENOG4105DHU	Bile acid
CU254_25205	ENOG4105EC2	ftsk spoIIIe
CU254_25225	ENOG4106F1P	AAA ATPase, central domain protein
CU254_25290	ENOG4108RVA	ribokinase
CU254_25310	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_25320	ENOG4107VFR	oxidoreductase
CU254_25325	ENOG4105DUX	Transporter
CU254_25340	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CU254_25345	ENOG4105CDA	abc transporter atp-binding protein
CU254_25350	ENOG4105E5Q	amino acid AbC transporter
CU254_25380	ENOG4105DJB	Major Facilitator Superfamily
CU254_25390	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
CU254_25395	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CU254_25400	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
CU254_25425	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_25430	ENOG4105EF1	ribulokinase
CU254_25440	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
CU254_25445	ENOG4105DFW	ABC transporter
CU254_25450	ENOG4105C2J	ABC transporter
CU254_25455	ENOG4107RNG	ABC transporter
CU254_25505	ENOG4108XW1	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
CU254_25525	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CU254_25570	ENOG4105ERH	Fumarylacetoacetate hydrolase
CU254_25590	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CU254_25595	ENOG4108IG5	Transcriptional regulator
CU254_25620	ENOG4105CSH	Transporter
CU254_25625	ENOG4108W9H	Tetr family transcriptional regulator
CU254_25630	ENOG4107S9B	Shikimate dehydrogenase
CU254_25680	ENOG4106JDR	secreted
CU254_25710	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CU254_25730	ENOG4108Z4X	TRANSCRIPTIONal
CU254_25735	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CU254_25745	ENOG4105EEM	helicase
CU254_25755	ENOG4105DV0	amidase (EC 3.5.1.4
CU254_25770	ENOG4107SVN	transposase
CU254_25775	ENOG4106KE4	Dehydrogenase
CU254_25785	ENOG4105C7W	Xanthine dehydrogenase
CU254_25790	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
CU254_25795	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
CU254_25820	ENOG41085W3	Transposase
CU254_25825	ENOG4107ETC	gas vesicle protein
CU254_25835	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
CU254_25860	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
CU254_25880	ENOG4105DQE	DNA ligase
CU254_25890	ENOG4105DQE	DNA ligase
CU254_25920	ENOG4105BZU	Histidine kinase
CU254_25955	ENOG410829K	Lysine exporter protein (Lyse ygga)
CU254_25995	ENOG4105EX0	alpha-galactosidase
CU254_26025	ENOG4105CSH	Transporter
CU254_26035	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CU254_26105	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
CU254_26110	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CU254_26155	ENOG4105CFC	Transporter
CU254_26200	ENOG410836F	Transposase
CU254_26260	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
CU254_26265	ENOG4105DZR	Type I site-specific deoxyribonuclease
CU254_26275	ENOG4105CVR	type I restriction-modification system
CU254_26320	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CU254_26335	ENOG4108KPJ	rna polymerase sigma factor
CU254_26355	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CU254_26370	ENOG4105BZU	Histidine kinase
CU254_26380	ENOG4108M15	ABC transporter
CU254_26385	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
CU254_26420	ENOG4108PJD	permease
CU254_26430	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CU254_26435	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
CU254_26460	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CU254_26475	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CU254_26485	ENOG4105K59	histidine triad (HIT) protein
CU254_26495	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CU254_26500	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CU254_26530	ENOG4105C26	Dehydrogenase
CU254_26555	ENOG4105EB3	Histidine kinase
CU254_26560	ENOG4108PYU	two-component system response regulator
CU254_26565	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CU254_26575	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
CU254_26665	ENOG4108IPT	Naphthoate synthase
CU254_26685	ENOG4105CB2	alcohol dehydrogenase
CU254_26695	ENOG4105CUB	amino acid
CU254_26715	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CU254_26720	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_26735	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CU254_26745	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
CU254_26750	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
CU254_26755	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CU254_26775	ENOG4105EPR	degv family
CU254_26780	ENOG4108TZC	
CU254_26785	ENOG4105CVJ	phosphoglycerate mutase
CU254_26795	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CU254_26800	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CU254_26805	ENOG4105CSH	Transporter
CU254_26810	ENOG4105C75	arginyL-tRNA synthetase
CU254_26815	ENOG4105YA8	Transcriptional regulator
CU254_26820	ENOG4108IPT	Naphthoate synthase
CU254_26825	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_26830	ENOG4105CHR	reductase
CU254_26835	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_26855	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CU254_26860	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CU254_26865	ENOG4105K46	50S ribosomal protein l27
CU254_26870	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CU254_26875	ENOG4105C03	ribonuclease
CU254_26875	ENOG4105C03	ribonuclease
CU254_26895	ENOG4105CJ1	ABC, transporter
CU254_26920	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CU254_26935	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU254_26945	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CU254_26965	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CU254_26980	ENOG41080V3	Major Facilitator superfamily
CU254_26990	ENOG4107TB5	TRANSCRIPTIONal
CU254_26995	ENOG4105CHR	reductase
CU254_27035	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CU254_27060	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CU254_27065	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CU254_27070	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CU254_27075	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CU254_27085	ENOG4105BZU	Histidine kinase
CU254_27090	ENOG4105EDW	glycosyl transferase, family 39
CU254_27100	ENOG4105EDW	glycosyl transferase, family 39
CU254_27145	ENOG41085W3	Transposase
CU254_27160	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CU254_27165	ENOG4107S9F	NmrA family
CU254_27170	ENOG4105KVH	Transcriptional regulator
CU254_27180	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
CU254_27185	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
CU254_27200	ENOG4105G6Z	alkaline phosphatase
CU254_27210	ENOG4105E2R	ROK family
CU254_27220	ENOG4105C5S	asparaginyl-tRNA synthetase
CU254_27225	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
CU254_27230	ENOG4105D9P	serine threonine protein kinase
CU254_27240	ENOG4105BZU	Histidine kinase
CU254_27285	ENOG4105CPC	Aldo Keto reductase
CU254_27365	ENOG4105C54	Major Facilitator superfamily
CU254_27370	ENOG4105KME	endoribonuclease L-psp
CU254_27390	ENOG4105C26	Dehydrogenase
CU254_27395	ENOG4107RSM	transcriptional regulator
CU254_27410	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_27415	ENOG4105BZU	Histidine kinase
CU254_27430	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
CU254_27440	ENOG41067SE	Tetr family transcriptional regulator
CU254_27480	ENOG4105F27	Major Facilitator
CU254_27490	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
CU254_27495	ENOG4105RV9	Transcriptional regulator
CU254_27520	ENOG4108YZG	isomerase
CU254_27535	ENOG4105MC2	DSBA oxidoreductase
CU254_27545	ENOG4109057	
CU254_27565	ENOG4105D8X	mechanosensitive ion channel
CU254_27575	ENOG4105CG3	alpha amylase, catalytic region
CU254_27585	ENOG4105VEQ	Cold shock protein
CU254_27615	ENOG4105C7I	Dehydrogenase
CU254_27765	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_27770	ENOG4105F95	Monooxygenase
CU254_27775	ENOG4107RR1	TRANSCRIPTIONal
CU254_27805	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU254_27810	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CU254_27820	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_27850	ENOG4105IW1	AmiS UreI transporter
CU254_27855	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
CU254_27860	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
CU254_27885	ENOG4105GRZ	Ycii-related protein
CU254_27900	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CU254_27905	ENOG4105KT7	mgtC SapB transporter
CU254_27915	ENOG4105VPX	protein, conserved in bacteria
CU254_27950	ENOG4107SVN	transposase
CU254_27960	ENOG4105CHP	RNA polymerase
CU254_27965	ENOG4105CIR	epoxide hydrolase
CU254_27970	ENOG4108J2P	Alpha beta hydrolase fold
CU254_27975	ENOG4105EMU	Dehydrogenase
CU254_27985	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
CU254_28015	ENOG4105CHR	reductase
CU254_28020	ENOG4107Z3H	Transcriptional regulator, TetR family
CU254_28035	ENOG4108MP6	LysR family Transcriptional regulator
CU254_28045	ENOG4105CHR	reductase
CU254_28085	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU254_28090	ENOG4105ECM	Sensor protein basS pmrB
CU254_28095	ENOG4105CUB	amino acid
CU254_28140	ENOG4105DQ6	Transposase
CU254_28165	ENOG4105DTD	Dehydrogenase
CU254_28170	ENOG4108UKI	Enoyl-CoA hydratase
CU254_28205	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_28215	ENOG4105CQ7	ATP-dependent helicase
CU254_28220	ENOG4107S91	Sodium hydrogen exchanger
CU254_28240	ENOG4105DCG	PHP domain protein
CU254_28250	ENOG4105DRR	Transcriptional regulator, GntR family
CU254_28285	ENOG4105GRZ	Ycii-related protein
CU254_28295	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CU254_28300	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
CU254_28320	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_28340	ENOG4105C2W	permease
CU254_28345	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CU254_28350	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CU254_28355	ENOG4105CKI	cobalamin synthesis protein
CU254_28365	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CU254_28395	ENOG4107SCK	Monooxygenase
CU254_28425	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CU254_28430	ENOG4105CBC	glutamate synthase
CU254_28440	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU254_28445	ENOG4105CSH	Transporter
CU254_28450	ENOG4105C5Q	Transcriptional regulator
CU254_28470	ENOG4105BZU	Histidine kinase
CU254_28475	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_28485	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CU254_28490	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CU254_28495	ENOG4108YZT	Adenosylcobinamide kinase
CU254_28500	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CU254_28510	ENOG410813T	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CU254_28525	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CU254_28530	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CU254_28540	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
CU254_28560	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
CU254_28565	ENOG4105J1Z	Arabinosyltransferase
CU254_28590	ENOG41081F0	Precorrin-8x methylmutase
CU254_28600	ENOG4105CJ1	ABC, transporter
CU254_28610	ENOG4105VZ8	Transcriptional regulator
CU254_28615	ENOG4105CTK	cobaltochelatase, cobn subunit
CU254_28620	ENOG4106UDK	Cellulose-binding, family II
CU254_28630	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CU254_28670	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_28685	ENOG4105C0H	protease
CU254_28695	ENOG4105D7A	ATP-binding protein
CU254_28700	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CU254_28755	ENOG4105DFU	Cell wall formation (By similarity)
CU254_28795	ENOG4105CUJ	penicillin amidase
CU254_28810	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CU254_28905	ENOG4105C0F	tryptophanase EC 4.1.99.1
CU254_28925	ENOG4108X07	Tetr family transcriptional regulator
CU254_28965	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU254_28980	ENOG410827T	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CU254_28985	ENOG4105CFG	Acts as a chaperone (By similarity)
CU254_29045	ENOG4105KVH	Transcriptional regulator
CU254_29060	ENOG4105C5H	ABC transporter
CU254_29070	ENOG4107SVN	transposase
CU254_29120	ENOG4105C3U	ABC transporter
CU254_29125	ENOG4108JQ7	(ABC) transporter
CU254_29130	ENOG4105C5Q	Transcriptional regulator
CU254_29135	ENOG4108J59	Extracellular solute-binding protein, family 5
CU254_29145	ENOG4105DUM	transcriptional regulator, lysR family
CU254_29165	ENOG4105EBR	Carboxylesterase
CU254_29200	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_29210	ENOG4105ENE	Histidine kinase
CU254_29225	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CU254_29230	ENOG4108R86	Transcriptional regulator
CU254_29265	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CU254_29280	ENOG4105C7K	acetolactate synthase
CU254_29300	ENOG4105MXW	flavin reductase domain protein, FMN-binding
CU254_29305	ENOG4105JSC	dimethylmenaquinone methyltransferase
CU254_29310	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CU254_29315	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CU254_29325	ENOG4105KHM	amidohydrolase 2
CU254_29330	ENOG4105EFA	4-hydroxyphenylacetate
CU254_29340	ENOG4105C7K	acetolactate synthase
CU254_29345	ENOG4108SV8	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
CU254_29350	ENOG4105BZU	Histidine kinase
CU254_29355	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CU254_29395	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
CU254_29400	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CU254_29405	ENOG4108R85	Short chain dehydrogenase
CU254_29410	ENOG4105C26	Dehydrogenase
CU254_29415	ENOG4105DRR	Transcriptional regulator, GntR family
CU254_29420	ENOG4105CHM	Aminotransferase
CU254_29430	ENOG4105C57	major facilitator superfamily
CU254_29460	ENOG41085W3	Transposase
CU254_29480	ENOG4105DTQ	mandelate racemase muconate lactonizing
CU254_29490	ENOG4107VHA	regulatoR
CU254_29495	ENOG41066YJ	Beta-lactamase
CU254_29505	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
CU254_29510	ENOG4108XHQ	(2Fe-2S)-binding domain protein
CU254_29530	ENOG4105CPP	Dehydrogenase, E1 component
CU254_29535	ENOG4107RUY	(E1 component), alpha subunit
CU254_29545	ENOG4107ISF	Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1- 2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids
CU254_29580	ENOG4105CJ1	ABC, transporter
CU254_29585	ENOG4105DEN	Luciferase family
CU254_29610	ENOG4105DRR	Transcriptional regulator, GntR family
CU254_29615	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CU254_29620	ENOG4105C26	Dehydrogenase
CU254_29630	ENOG41063TF	transcriptional regulator (AraC
CU254_29655	ENOG4105C0Z	ABC transporter
CU254_29660	ENOG4108IV0	ABC, transporter
CU254_29720	ENOG4105C26	Dehydrogenase
CU254_29740	ENOG4105DZC	cytosine deaminase
CU254_29745	ENOG4107S5I	aldo keto reductase
CU254_29760	ENOG4108KPJ	rna polymerase sigma factor
CU254_29770	ENOG41082YX	Transcriptional regulator, arsr family
CU254_29810	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CU254_29820	ENOG4105C26	Dehydrogenase
CU254_29825	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CU254_29840	ENOG4105XMC	MarR family Transcriptional regulator
CU254_29855	ENOG4107SVN	transposase
CU254_29875	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CU254_29910	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
CU254_29940	ENOG4105CDH	Citrulline--aspartate ligase
CU254_29960	ENOG4108MUZ	hydrolase
CU254_29965	ENOG4108Q5F	Tetr family transcriptional regulator
CU254_29970	ENOG4105GFG	DUF218 domain
CU254_30005	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
CU254_30020	ENOG4105CHP	RNA polymerase
CU254_30040	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CU254_30045	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CU254_30055	ENOG41064MX	Tetr family transcriptional regulator
CU254_30060	ENOG4108IG5	Transcriptional regulator
CU254_30095	ENOG4108JA1	polyketide synthase
CU254_30110	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CU254_30135	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
CU254_30140	ENOG4107QQG	Dehydrogenase
CU254_30245	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_30255	ENOG4105D8K	carboxyl transferase
CU254_30295	ENOG4107QSN	dihydrolipoamide acetyltransferase
CU254_30315	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CU254_30320	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU254_30340	ENOG4108YRB	methyltransferase
CU254_30345	ENOG4108YRB	methyltransferase
CU254_30350	ENOG4105CMG	Carbohydrate kinase
CU254_30365	ENOG4105EMN	RNA polymerase sigma factor
CU254_30405	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CU254_30415	ENOG4105CGU	Enoyl-CoA hydratase
CU254_30495	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_30510	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CU254_30515	ENOG4105EW9	transcriptional regulator AsnC family
CU254_30525	ENOG4105JQZ	Methyltransferase
CU254_30555	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_30565	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_30570	ENOG4108JQ6	ABC transporter
CU254_30595	ENOG4105DBE	peroxidase
CU254_30600	ENOG410650H	(LipO)protein
CU254_30610	ENOG4105CHR	reductase
CU254_30620	ENOG4105BZW	Glycerate kinase
CU254_30630	ENOG4105C7N	Xanthine uracil vitamin C permease
CU254_30635	ENOG4107Y2X	deaminase
CU254_30665	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU254_30685	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_30695	ENOG4105CPN	adenine deaminase
CU254_30705	ENOG4105DYW	oxidoreductase
CU254_30715	ENOG4107YPT	transcriptional regulator
CU254_30725	ENOG4105ECQ	AraC Family Transcriptional Regulator
CU254_30740	ENOG4105N14	lysine exporter protein LysE YggA
CU254_30755	ENOG4107RN3	metallophosphoesterase
CU254_30765	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
CU254_30770	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CU254_30790	ENOG4105GWZ	Roadblock lc7 family protein
CU254_30795	ENOG4105DHQ	Histidine kinase
CU254_30805	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
CU254_30815	ENOG41082BZ	phosphocarrier protein (HPr)
CU254_30820	ENOG4105DM4	PTS System
CU254_30830	ENOG4105DE4	1-phosphofructokinase
CU254_30840	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CU254_30845	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CU254_30855	ENOG4105BZU	Histidine kinase
CU254_30865	ENOG4107TB5	TRANSCRIPTIONal
CU254_30875	ENOG4107RN6	Monooxygenase
CU254_30910	ENOG4108Z6Z	Transcriptional regulator
CU254_30945	ENOG4107RSM	transcriptional regulator
CU254_30975	ENOG4105BZU	Histidine kinase
CU254_30980	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU254_30985	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CU254_30990	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CU254_31000	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CU254_31055	ENOG4107RKP	Nicotinate phosphoribosyltransferase
CU254_31060	ENOG4108RWI	nicotinamidase
CU254_31070	ENOG4105VKD	bioY protein
CU254_31100	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CU254_31110	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CU254_31120	ENOG4105C57	major facilitator superfamily
CU254_31155	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU254_31160	ENOG41080Z8	PHOSPHOCARRIER protein
CU254_31170	ENOG4105CMT	Dihydroxyacetone kinase
CU254_31200	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CU254_31205	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
CU254_31220	ENOG4105ECQ	AraC Family Transcriptional Regulator
CU254_31230	ENOG4105RFZ	Methylmalonyl-coA mutase
CU254_31250	ENOG4105N14	lysine exporter protein LysE YggA
CU254_31260	ENOG4107S9F	NmrA family
CU254_31265	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
CU254_31275	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CU254_31295	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CU254_31300	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CU254_31305	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CU254_31310	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CU254_31315	ENOG4108SBS	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CU254_31320	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CU254_31325	ENOG4106DE0	ATP synthase
CU254_31330	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
CU254_31340	ENOG4105ESV	Glycosyl transferase, family 4
CU254_31365	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CU254_31370	ENOG4108Z6Z	Transcriptional regulator
CU254_31375	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
CU254_31380	ENOG41085W3	Transposase
CU254_31385	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CU254_31395	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CU254_31400	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CU254_31415	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CU254_31420	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CU254_31425	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
CU254_31430	ENOG4105D6E	homoserine dehydrogenase
CU254_31435	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CU254_31440	ENOG4105C75	arginyL-tRNA synthetase
CU254_31460	ENOG4105EW6	flavin reductase domain protein, FMN-binding
CU254_31470	ENOG4105CIR	epoxide hydrolase
CU254_31485	ENOG4105F27	Major Facilitator
CU254_31490	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CU254_31535	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CU254_31545	ENOG4105CSH	Transporter
CU254_31550	ENOG4105DNP	FAD linked oxidase domain protein
CU254_31570	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CU254_31590	ENOG4105W1N	transcriptional regulator
CU254_31610	ENOG4105DND	Transcriptional regulator
CU254_31620	ENOG4107STQ	Multicopper oxidase
CU254_31625	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_31640	ENOG4105CIG	ABC transporter
CU254_31660	ENOG4105F95	Monooxygenase
CU254_31670	ENOG4108KPJ	rna polymerase sigma factor
CU254_31680	ENOG4105I4A	GCN5-related N-acetyltransferase
CU254_31695	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CU254_31720	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CU254_31725	ENOG4105FDP	GntR family transcriptional regulator
CU254_31735	ENOG4105C26	Dehydrogenase
CU254_31740	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CU254_31750	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_31755	ENOG4105BZU	Histidine kinase
CU254_31800	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_31815	ENOG4105CHR	reductase
CU254_31820	ENOG4105F04	LysR family Transcriptional regulator
CU254_31850	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_31855	ENOG4105CMQ	Chloride channel
CU254_31865	ENOG4107RRE	RNA-directed DNA polymerase
CU254_31920	ENOG4105XYF	acetyltransferase
CU254_31940	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CU254_31950	ENOG4105CSH	Transporter
CU254_31955	ENOG4105DRR	Transcriptional regulator, GntR family
CU254_31975	ENOG4105C7K	acetolactate synthase
CU254_31985	ENOG4108FN7	Aldo keto reductase
CU254_32000	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_32020	ENOG4105EMF	GntR family transcriptional regulator
CU254_32035	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CU254_32045	ENOG4108JPW	Aminotransferase
CU254_32090	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU254_32095	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_32115	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_32145	ENOG4105KVH	Transcriptional regulator
CU254_32160	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CU254_32165	ENOG4105EMU	Dehydrogenase
CU254_32175	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_32185	ENOG4107QX3	carboxylase
CU254_32195	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CU254_32205	ENOG4105DWV	Homoserine O-trans-acetylase
CU254_32235	ENOG4105DCF	alanine dehydrogenase
CU254_32240	ENOG4105BZ1	(ABC) transporter
CU254_32270	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CU254_32305	ENOG4105E90	ABC transporter
CU254_32310	ENOG4105E90	ABC transporter
CU254_32315	ENOG4108IJ8	ABC transporter
CU254_32330	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CU254_32345	ENOG4108ZM9	phosphoglycerate mutase
CU254_32355	ENOG4106JDR	secreted
CU254_32365	ENOG4105CBD	Diacylglycerol kinase
CU254_32390	ENOG4105EMN	RNA polymerase sigma factor
CU254_32395	ENOG4108Z66	YbaK ebsC protein
CU254_32400	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_32420	ENOG4105EBR	Carboxylesterase
CU254_32430	ENOG4108RAV	Conserved protein
CU254_32435	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CU254_32465	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CU254_32470	ENOG4105PAD	Hydrolase
CU254_32480	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CU254_32485	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
CU254_32495	ENOG4108MKR	lipoprotein lpqb
CU254_32500	ENOG4105BZU	Histidine kinase
CU254_32505	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU254_32510	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
CU254_32530	ENOG41082JN	Transcriptional regulator
CU254_32550	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CU254_32585	ENOG4105CUB	amino acid
CU254_32595	ENOG4105KDP	XRE family
CU254_32605	ENOG4105EIP	mannose-6-phosphate isomerase
CU254_32640	ENOG4107RGC	Glycosyl transferase, family 2
CU254_32645	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
CU254_32650	ENOG4107XZ0	Peptidase M50
CU254_32665	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
CU254_32670	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_32675	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU254_32690	ENOG4108JQ7	(ABC) transporter
CU254_32695	ENOG4107USK	Extracellular solute-binding protein, family 5
CU254_32700	ENOG4105CI3	gtp-binding protein typa
CU254_32715	ENOG4105C31	Tryptophanyl-tRNA synthetase
CU254_32725	ENOG4105JJR	Histidine kinase
CU254_32730	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU254_32740	ENOG4105CJ1	ABC, transporter
CU254_32750	ENOG4108UCS	ABC, transporter
CU254_32765	ENOG410842T	Pterin carbinolamine dehydratase
CU254_32785	ENOG4105C3G	gtp-binding protein
CU254_32800	ENOG4105EYH	Exonuclease
CU254_32805	ENOG4107RH8	nuclease SbcCD subunit D
CU254_32820	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CU254_32830	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CU254_32840	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CU254_32855	ENOG4105CAY	ferredoxin--nadp reductase
CU254_32860	ENOG4105C9Q	fumarate hydratase class II
CU254_32870	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU254_32915	ENOG4108IAB	Phoh family
CU254_32945	ENOG4105C7Z	Conserved Protein
CU254_32975	ENOG4105T1M	mycothiol conjugate amidase mca
CU254_32985	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CU254_32995	ENOG4108VVK	transcriptional Regulator, AsnC
CU254_33000	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CU254_33030	ENOG4105C7B	Threonine dehydratase
CU254_33070	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_33075	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CU254_33080	ENOG41066VF	YeeE YedE family protein
CU254_33165	ENOG4108VB1	regulatoR
CU254_33170	ENOG4105D17	glycoside hydrolase, family 3 domain protein
CU254_33190	ENOG41061H0	Monooxygenase
CU254_33195	ENOG4105ETS	cytosine purines uracil thiamine allantoin
CU254_33205	ENOG4105CFG	Acts as a chaperone (By similarity)
CU254_33220	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_33235	ENOG4105DRS	transport system, permease
CU254_33270	ENOG4108UZE	carboxy-peptidase
CU254_33295	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
CU254_33315	ENOG4108ZJ4	polysaccharide deacetylase
CU254_33325	ENOG4107TB5	TRANSCRIPTIONal
CU254_33340	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
CU254_33350	ENOG4105J4Q	Transcriptional regulator
CU254_33355	ENOG4108TCS	Glutamyl endopeptidase
CU254_33360	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_33370	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU254_33430	ENOG4108K8K	Transcriptional regulator
CU254_33435	ENOG4105DTQ	mandelate racemase muconate lactonizing
CU254_33470	ENOG4105EBR	Carboxylesterase
CU254_33490	ENOG4105EEF	Alkane 1-monooxygenase
CU254_33505	ENOG4105D2S	major facilitator superfamily
CU254_33515	ENOG4105CEP	NADH dehydrogenase
CU254_33540	ENOG4108M15	ABC transporter
CU254_33555	ENOG4106JDR	secreted
CU254_33565	ENOG4108JQ7	(ABC) transporter
CU254_33570	ENOG4105C3U	ABC transporter
CU254_33575	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_33580	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU254_33585	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_33595	ENOG4105CHR	reductase
CU254_33600	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CU254_33605	ENOG4105C5Q	Transcriptional regulator
CU254_33630	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CU254_33660	ENOG410650H	(LipO)protein
CU254_33665	ENOG4105DBE	peroxidase
CU254_33670	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CU254_33705	ENOG4105DXN	mazG family
CU254_33725	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CU254_33735	ENOG4108K81	inner membrane protein YghB
CU254_33745	ENOG4105BZU	Histidine kinase
CU254_33750	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_33755	ENOG4105D8V	Glucose sorbosone dehydrogenase
CU254_33760	ENOG4105CHR	reductase
CU254_33780	ENOG4108IG5	Transcriptional regulator
CU254_33800	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CU254_33820	ENOG4108IG5	Transcriptional regulator
CU254_33840	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CU254_33845	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CU254_33855	ENOG4107RCI	amp-dependent synthetase and ligase
CU254_33860	ENOG4105C5H	ABC transporter
CU254_33865	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CU254_33875	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CU254_33880	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CU254_33885	ENOG4106839	domain protein
CU254_33890	ENOG4105F8V	Hydrolase, tatD family
CU254_33895	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CU254_33920	ENOG4105CRQ	synthase (Component I)
CU254_33925	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CU254_33955	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CU254_33965	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CU254_33975	ENOG4105E2D	ec 3.2.1.52
CU254_33980	ENOG4108RPX	mosc domain containing protein
CU254_33990	ENOG4105C26	Dehydrogenase
CU254_34050	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CU254_34055	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_34090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CU254_34095	ENOG4107S9D	Alpha beta hydrolase
CU254_34100	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CU254_34110	ENOG4107RSM	transcriptional regulator
CU254_34125	ENOG4108KXM	LysR family Transcriptional regulator
CU254_34135	ENOG4105CNA	YD repeat protein
CU254_34175	ENOG4105D9U	N-acetyltransferase
CU254_34185	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CU254_34190	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
CU254_34215	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CU254_34230	ENOG4105BZU	Histidine kinase
CU254_34235	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU254_34270	ENOG4105C0H	protease
CU254_34280	ENOG4105E98	transcriptional regulator DeoR family
CU254_34290	ENOG4105ETX	regulatoR
CU254_34295	ENOG4107ZT3	family UPF0126
CU254_34300	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_34310	ENOG4105EBR	Carboxylesterase
CU254_34335	ENOG4105C0D	helicase
CU254_34345	ENOG4107QMH	DNA methylase
CU254_34350	ENOG4105D8D	Type III
CU254_34380	ENOG4107S9F	NmrA family
CU254_34485	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
CU254_34495	ENOG4105X7H	acyl-CoA dehydrogenase
CU254_34500	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CU254_34505	ENOG4106NZI	LysR family Transcriptional regulator
CU254_34530	ENOG4105EEF	Alkane 1-monooxygenase
CU254_34550	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CU254_34580	ENOG4105DQE	DNA ligase
CU254_34595	ENOG4106NZI	LysR family Transcriptional regulator
CU254_34635	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_34655	ENOG4107RGD	Major Facilitator superfamily
CU254_34660	ENOG4105CFM	UPF0317 protein
CU254_34665	ENOG4105E7W	lamb ycsf family protein
CU254_34675	ENOG4107R7A	Allophanate hydrolase subunit 2
CU254_34680	ENOG4105CF1	Alkylated DNA repair protein
CU254_34700	ENOG4105KST	dependent repressor
CU254_34715	ENOG4105E39	Enoyl-CoA hydratase
CU254_34720	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_34740	ENOG4105E4F	Isochorismate synthase
CU254_34755	ENOG4107FKK	extracellular solute-binding protein family 1
CU254_34760	ENOG4105ECW	sulfate abc transporter
CU254_34765	ENOG4105DRS	transport system, permease
CU254_34810	ENOG4105CQB	FAD linked oxidase domain protein
CU254_34835	ENOG4108IUX	(ABC) transporter
CU254_34840	ENOG4105RHA	ABC transporter, permease
CU254_34845	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CU254_34865	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CU254_34875	ENOG4105C1G	acyl-Coa dehydrogenase
CU254_34895	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU254_34910	ENOG4105J7D	transcriptional regulator
CU254_34925	ENOG4107T8T	UPF0173 metal-dependent hydrolase
CU254_34930	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CU254_34940	ENOG4105C85	amino acid
CU254_34945	ENOG4107EPV	Aminotransferase class V
CU254_34950	ENOG4106IPI	cyclase, family
CU254_34955	ENOG4105C7K	acetolactate synthase
CU254_34980	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CU254_34990	ENOG4105MT3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CU254_34995	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CU254_35005	ENOG4105CQM	Urea amidohydrolase subunit alpha
CU254_35010	ENOG4105KI2	Urea amidohydrolase subunit beta
CU254_35015	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CU254_35045	ENOG4105ENE	Histidine kinase
CU254_35055	ENOG4105CMD	Transcriptional regulator, GntR family
CU254_35060	ENOG4108KD5	ADP-ribosylation crystallin J1
CU254_35070	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CU254_35080	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CU254_35100	ENOG4105FCS	tRNA rRNA methyltransferase
CU254_35125	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
CU254_35130	ENOG4107SFI	Major Facilitator superfamily
CU254_35140	ENOG4105C7N	Xanthine uracil vitamin C permease
CU254_35165	ENOG4108N0W	Major Facilitator superfamily
CU254_35175	ENOG4105VEQ	Cold shock protein
CU254_35195	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
CU254_35200	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_35210	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CU254_35215	ENOG410901E	Membrane
CU254_35230	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CU254_35270	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CU254_35315	ENOG4105GWZ	Roadblock lc7 family protein
CU254_35330	ENOG4105GWZ	Roadblock lc7 family protein
CU254_35340	ENOG4107Z6I	Thiamine biosynthesis protein
CU254_35350	ENOG4105DG7	nitrate ABC transporter
CU254_35355	ENOG4105D7T	ABC transporter
CU254_35365	ENOG4107T8P	acyl-Coa dehydrogenase
CU254_35375	ENOG4106N3A	copper homeostasis protein cutc
CU254_35395	ENOG4105CFI	type iii restriction protein res subunit
CU254_35415	ENOG4105CNF	WD-40 repeat protein
CU254_35420	ENOG4107TCW	O-succinylbenzoate synthase
CU254_35430	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CU254_35440	ENOG4105VEQ	Cold shock protein
CU254_35465	ENOG4105Y3U	Transglycosylase-associated protein
CU254_35475	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
CU254_35505	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CU254_35510	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CU254_35515	ENOG4105DWF	phosphomethylpyrimidine kinase
CU254_35550	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CU254_35560	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CU254_35565	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CU254_35575	ENOG4105C7B	Threonine dehydratase
CU254_35585	ENOG4108RU0	short-chain dehydrogenase reductase
CU254_35590	ENOG4107MHI	Transcriptional regulator, MarR family
CU254_35595	ENOG4105C57	major facilitator superfamily
CU254_35600	ENOG4105FDP	GntR family transcriptional regulator
CU254_35605	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CU254_35620	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CU254_35655	ENOG4105EV8	ectoine hydroxylase
CU254_35660	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
CU254_35670	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
CU254_35680	ENOG4106MP8	UPF0754 membrane protein
CU254_35695	ENOG41060H3	Protein of unknown function (DUF1049)
CU254_35715	ENOG4107YPT	transcriptional regulator
CU254_35770	ENOG4108UYE	Lactoylglutathione lyase
CU254_35780	ENOG4105K4P	CoA-binding domain protein
CU254_35790	ENOG4105ETX	regulatoR
CU254_35795	ENOG41062D9	Histidine kinase
CU254_35800	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CU254_35805	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CU254_35810	ENOG4106P37	HTH-type transcriptional regulator YjhI
CU254_35815	ENOG4105CHP	RNA polymerase
CU254_35825	ENOG4105GRZ	Ycii-related protein
CU254_35840	ENOG4106A3M	Cytochrome p-450
CU254_35845	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CU254_35850	ENOG4105C29	acyl-CoA thioesterase
CU254_35875	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CU254_35890	ENOG4107UWN	reductase
CU254_35895	ENOG4105BZU	Histidine kinase
CU254_35910	ENOG4105FUY	alpha subunit
CU254_35930	ENOG4105CSH	Transporter
CU254_35995	ENOG4105I6B	RNA polymerase
CU254_36005	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CU254_36015	ENOG4108VJ1	Transcriptional regulator (CarD family
CU254_36020	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CU254_36025	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CU254_36045	ENOG4105C8N	cysteinyl-tRNA synthetase
CU254_36050	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CU254_36060	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
CU254_36070	ENOG4105CR5	Class II aldolase adducin family protein
CU254_36080	ENOG4108M3J	Dehydrogenase
CU254_36085	ENOG4107YVI	ribose 5-phosphate isomerase
CU254_36090	ENOG4105CMT	Dihydroxyacetone kinase
CU254_36095	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
CU254_36100	ENOG4105CVJ	phosphoglycerate mutase
CU254_36105	ENOG4105MVE	transcriptional regulator
CU254_36110	ENOG4105IE8	Alpha-ketoglutarate permease
CU254_36115	ENOG4107S5T	Carbohydrate kinase
CU254_36135	ENOG4106MP8	UPF0754 membrane protein
CU254_36150	ENOG4105E98	transcriptional regulator DeoR family
CU254_36155	ENOG4105CC5	ABC transporter
CU254_36160	ENOG4105E0A	ABC, transporter
CU254_36165	ENOG4105DSE	periplasmic solute binding protein
CU254_36180	ENOG4105CEN	a g-specific adenine glycosylase
CU254_36250	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
CU254_36255	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CU254_36265	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU254_36290	ENOG4105CRK	lysyL-tRNA synthetase
CU254_36300	ENOG4105KPY	Small multidrug resistance protein
CU254_36305	ENOG4108KPJ	rna polymerase sigma factor
CU254_36315	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CU254_36320	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CU254_36325	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CU254_36350	ENOG4105W1Y	Transcriptional regulator
CU254_36375	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CU254_36405	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CU254_36420	ENOG4105F0N	pyrophosphate phospho-hydrolase
CU254_36430	ENOG4105GRZ	Ycii-related protein
CU254_36435	ENOG4105CHP	RNA polymerase
CU254_36440	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CU254_36465	ENOG4105NPE	arsR family transcriptional regulator
CU254_36495	ENOG4105C6E	dna polymerase iii
CU254_36500	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CU254_36515	ENOG4106UW1	Major Facilitator superfamily
CU254_36520	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CU254_36545	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CU254_36550	ENOG4108I5C	dEAD DEAH box helicase
CU254_36600	ENOG4105D17	glycoside hydrolase, family 3 domain protein
CU254_36605	ENOG4105EHZ	conserved protein UCP016719
CU254_36610	ENOG4107S1E	Beta-lactamase
CU254_36615	ENOG4106KNT	transcriptional regulator
CU254_36620	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CU254_36625	ENOG4105D9G	High-affinity
CU254_36630	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CU254_36635	ENOG4108KPJ	rna polymerase sigma factor
CU254_36640	ENOG4107S5I	aldo keto reductase
CU254_36670	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CU254_36680	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CU254_36735	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_36755	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CU254_36765	ENOG4105DUX	Transporter
CU254_36770	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CU254_36780	ENOG4105D74	hydrolase
CU254_36835	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CU254_36885	ENOG4105BZ4	penicillin-binding protein
CU254_36890	ENOG4107RGJ	metallophosphoesterase
CU254_36915	ENOG4105CVK	Glutamate decarboxylase
CU254_36920	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
CU254_36925	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CU254_36955	ENOG4105E0Y	RtcB Protein
CU254_36980	ENOG4105CFH	Aspartokinase
CU254_37015	ENOG4105DMW	Dehydrogenase reductase
CU254_37025	ENOG4105C5Q	Transcriptional regulator
CU254_37030	ENOG4108594	Permease of the drug metabolite transporter
CU254_37040	ENOG4108RHM	integral membrane protein
CU254_37045	ENOG4105CHP	RNA polymerase
CU254_37060	ENOG4108JQ7	(ABC) transporter
CU254_37065	ENOG4105C3U	ABC transporter
CU254_37070	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_37075	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU254_37080	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU254_37100	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CU254_37115	ENOG4105CKK	Glycosyl transferase, family 2
CU254_37120	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CU254_37130	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CU254_37135	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CU254_37140	ENOG4108RU2	n-acetylmuramoyl-l-alanine amidase
CU254_37180	ENOG4105C7B	Threonine dehydratase
CU254_37185	ENOG4105EDW	glycosyl transferase, family 39
CU254_37190	ENOG4105BZU	Histidine kinase
CU254_37195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU254_37220	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU254_37225	ENOG4105C7B	Threonine dehydratase
CU254_37250	ENOG4105D9P	serine threonine protein kinase
CU254_37255	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CU254_37270	ENOG4105C57	major facilitator superfamily
CU254_37295	ENOG4105EC2	ftsk spoIIIe
CU254_37315	ENOG4108MUZ	hydrolase
CU254_37320	ENOG41067SE	Tetr family transcriptional regulator
CU254_37325	ENOG4105E2B	Taurine dioxygenase
CU254_37340	ENOG4108XW1	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
CU254_37350	ENOG4108Z6B	deaminase
CU254_37360	ENOG4105CH2	amidohydrolase
CU254_37370	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CU254_37440	ENOG4105D74	hydrolase
CU254_37445	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
CU254_37450	ENOG4105BZU	Histidine kinase
CU254_37465	ENOG4108RCF	TRANSCRIPTIONal
CU254_37475	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CU254_37495	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CU254_37500	ENOG4107NHD	transcriptional regulator
CU254_37520	ENOG4105KHC	sulfurtransferase
CU254_37525	ENOG4105PKJ	carbohydrate binding
CU254_37535	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
CU254_37545	ENOG4107R7A	Allophanate hydrolase subunit 2
CU254_37565	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CU254_37580	ENOG4108TAC	
CU254_37605	ENOG4105BZ1	(ABC) transporter
CU254_37630	ENOG4108YZN	class I peptide chain release factor
CU254_37690	ENOG4107Y03	Nitroreductase
CU254_37695	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
CU254_37700	ENOG4105BZ1	(ABC) transporter
CU254_37705	ENOG4105BZ1	(ABC) transporter
CU254_37720	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CU254_37725	ENOG410839H	phosphoribosylformylglycinamidine synthase
CU254_37755	ENOG4105DMF	Dehydrogenase
CU254_37795	ENOG4105C8V	SAICAR synthetase
CU254_37820	ENOG4105EAD	ABC transporter
CU254_37835	ENOG4105C83	adenylosuccinate lyase
CU254_37840	ENOG4105CXK	mandelate racemase muconate lactonizing
CU254_37845	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CU254_37850	ENOG4108RTU	Aldolase
CU254_37900	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
CU254_37915	ENOG4108FKH	Transglycosylase SLT domain
CU254_37950	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CU254_37970	ENOG4105DYW	oxidoreductase
CU254_37985	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CU254_38015	ENOG4105BZU	Histidine kinase
CU254_38045	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CU254_38060	ENOG4105CPC	Aldo Keto reductase
CU254_38065	ENOG4108BAS	reductase
CU254_38085	ENOG4107RN6	Monooxygenase
CU254_38110	ENOG4105CE4	GlcNAc 6-P deacetylase
CU254_38120	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
CU254_38125	ENOG4105CQB	FAD linked oxidase domain protein
CU254_38130	ENOG4105FQ6	thiopurine methyltransferase
CU254_38145	ENOG4105C57	major facilitator superfamily
CU254_38155	ENOG410905P	Pyridoxamine 5-phosphate
CU254_38175	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
CU254_38195	ENOG4105DBI	uridine monophosphokinase
CU254_38200	ENOG4108MGF	sugar kinase
CU254_38205	ENOG4105C2J	ABC transporter
CU254_38210	ENOG4105CNN	ABC, transporter
CU254_38215	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
CU254_38220	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_38225	ENOG4105ETE	Transcriptional regulator (LacI family
CU254_38235	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CU254_38260	ENOG4105EMN	RNA polymerase sigma factor
CU254_38275	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CU254_38280	ENOG4108IXY	short-chain dehydrogenase reductase
CU254_38290	ENOG4105J1Z	Arabinosyltransferase
CU254_38295	ENOG4105F9F	transposase
CU254_38310	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU254_38345	ENOG4105KNI	merR family transcriptional Regulator
CU254_38350	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CU254_38355	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CU254_38360	ENOG4105CFG	Acts as a chaperone (By similarity)
CU254_38395	ENOG410814C	multidrug resistance protein
CU254_38400	ENOG4105DF6	Fe-S oxidoreductase
CU254_38410	ENOG4105K4I	Scp-like extracellular
CU254_38415	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CU254_38425	ENOG4108V8F	Transcriptional regulator, MarR family
CU254_38430	ENOG41061H0	Monooxygenase
CU254_38435	ENOG4105DHP	deoxycytidine triphosphate deaminase
CU254_38455	ENOG4105C85	amino acid
CU254_38485	ENOG4105CSU	acyl-Coa dehydrogenase
CU254_38490	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_38495	ENOG4108VCA	G U mismatch-specific DNA glycosylase
CU254_38500	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CU254_38520	ENOG41073R8	VanW family
CU254_38525	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CU254_38575	ENOG4105EAB	amino acid AbC transporter
CU254_38595	ENOG4105TVJ	transport system, permease
CU254_38600	ENOG4105DQ5	transport system permease protein
CU254_38610	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CU254_38620	ENOG4105CPP	Dehydrogenase, E1 component
CU254_38625	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
CU254_38640	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CU254_38650	ENOG4105FS0	cytoplasmic membrane protein
CU254_38675	ENOG4107Z3H	Transcriptional regulator, TetR family
CU254_38680	ENOG4108F01	MaoC domain protein
CU254_38685	ENOG4105CHR	reductase
CU254_38690	ENOG4105CHU	acetyl-coa acetyltransferase
CU254_38710	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
CU254_38730	ENOG4105F9F	transposase
CU254_38765	ENOG4108WUZ	(ABC) transporter
CU254_38775	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
CU254_38795	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CU254_38820	ENOG4105BZU	Histidine kinase
CU254_38825	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_38840	ENOG4105CJ1	ABC, transporter
CU254_38855	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CU254_38865	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU254_38875	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_38880	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CU254_38885	ENOG4105EMU	Dehydrogenase
CU254_38890	ENOG4107ISF	Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1- 2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids
CU254_38905	ENOG4105DXB	Major Facilitator superfamily
CU254_38915	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
CU254_38935	ENOG4105BZ4	penicillin-binding protein
CU254_38940	ENOG4105BZ4	penicillin-binding protein
CU254_38945	ENOG4105D9R	oxidoreductase
CU254_38950	ENOG4105E2R	ROK family
CU254_38985	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
CU254_38995	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CU254_39000	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CU254_39030	ENOG4105YVS	arsR family transcriptional regulator
CU254_39045	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CU254_39070	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_39085	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CU254_39090	ENOG4108RVA	ribokinase
CU254_39100	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CU254_39120	ENOG4105C8T	Leucyl-tRNA synthetase
CU254_39135	ENOG41081DT	UPF0301 protein
CU254_39170	ENOG4108XG2	Histidine kinase
CU254_39175	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CU254_39215	ENOG4105C3M	thioredoxin reductase
CU254_39220	ENOG4108E1C	hydrolase
CU254_39235	ENOG4105CPF	Cell wall formation (By similarity)
CU254_39245	ENOG4107QJE	Chromosome Partitioning Protein
CU254_39250	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CU254_39260	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CU254_39265	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CU254_39270	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CU254_39275	ENOG41084CH	50S ribosomal protein l34
CU254_39280	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CU254_39285	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CU254_39290	ENOG4108J5G	6-phosphogluconate dehydrogenase
CU254_39295	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CU254_39300	ENOG4105K7N	UPF0232 protein
CU254_39305	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU254_39310	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU254_39375	ENOG4105EEM	helicase
CU254_39380	ENOG4108VJY	integral membrane protein
CU254_39400	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CU254_39420	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CU254_39445	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
CU254_39465	ENOG4108U4N	(sortase) family
CU254_39475	ENOG4108M8W	Monooxygenase
CU254_39490	ENOG4105CJ1	ABC, transporter
CU254_39500	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_39510	ENOG4105CIS	alcohol dehydrogenase
CU254_39525	ENOG4105CIG	ABC transporter
CU254_39540	ENOG4105D9P	serine threonine protein kinase
CU254_39545	ENOG4107TPY	serine threonine protein kinase
CU254_39550	ENOG4105CJN	penicillin-binding protein
CU254_39565	ENOG4105HZM	Fha domain containing protein
CU254_39570	ENOG4105TV9	FHA Domain-Containing protein
CU254_39650	ENOG41073TP	transcriptional regulator
CU254_39655	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
CU254_39665	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU254_39690	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU254_39700	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CU254_39710	ENOG4105CI0	Citrate lyase
CU254_39725	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CU254_39760	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
CU254_39795	ENOG4108T5E	Copper resistance protein
CU254_39810	ENOG4105E90	ABC transporter
CU254_39815	ENOG4108IJ8	ABC transporter
CU254_39820	ENOG4105E90	ABC transporter
CU254_39825	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
CU254_39845	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CU254_39855	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CU254_39890	ENOG4105BZU	Histidine kinase
CU254_39895	ENOG4105WH1	Two component transcriptional regulator luxr family
CU254_39970	ENOG4108HRK	Histidine kinase
CU254_39980	ENOG4105DY9	regulatoR
CU254_39990	ENOG4107QN1	sodium solute
CU254_39995	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CU254_40010	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CU254_40015	ENOG4105T1M	mycothiol conjugate amidase mca
CU254_40035	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CU254_40055	ENOG4105CEU	Arginine dihydrolase
CU254_40100	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CU254_40105	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CU254_40110	ENOG4108JJ9	ABC, transporter
CU254_40120	ENOG4105CIR	epoxide hydrolase
CU254_40160	ENOG4105CS9	pantothenic acid kinase
CU254_40165	ENOG4108UVJ	appr-1-p processing domain protein
CU254_40175	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CU254_40210	ENOG4106032	Glutathionylspermidine synthase
CU254_40220	ENOG4108J2P	Alpha beta hydrolase fold
CU254_40230	ENOG4105C8Y	Acetylornithine aminotransferase
CU254_40235	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CU254_40250	ENOG4105D5U	fad dependent oxidoreductase
CU254_40260	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CU254_40275	ENOG4108UW5	maltose o-acetyltransferase
CU254_40300	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CU254_40305	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CU254_40315	ENOG4105CHR	reductase
CU254_40320	ENOG4105CEY	Amp-dependent synthetase and ligase
CU254_40355	ENOG4108KP7	hydrolase
CU254_40360	ENOG4105DYW	oxidoreductase
CU254_40380	ENOG4106YN8	Prenyltransferase
CU254_40420	ENOG4108RG3	short-chain dehydrogenase reductase
CU254_40425	ENOG4105IQ5	FAD linked oxidase domain protein
CU254_40435	ENOG410602S	Transferase
CU254_40475	ENOG4108MKI	Glycosyl transferase, family 2
CU254_40495	ENOG4105CIR	epoxide hydrolase
CU254_40500	ENOG4108VC7	Protein of unknown function (DUF2587)
CU254_40510	ENOG4105CPQ	Dehydrogenase
CU254_40530	ENOG41087WU	
CU254_40540	ENOG4105DG4	malate L-lactate dehydrogenase
CU254_40565	ENOG4108MRH	transcriptional regulatory protein
CU254_40570	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CU254_40595	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
CU254_40605	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CU254_40610	ENOG4106T9R	serine protease
CU254_40615	ENOG4105KF0	sporulation and cell division protein, SsgA
CU254_40625	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CU254_40655	ENOG41073TP	transcriptional regulator
CU254_40675	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CU254_40685	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CU254_40690	ENOG4105CRK	lysyL-tRNA synthetase
CU254_40730	ENOG4105BZ1	(ABC) transporter
CU254_40740	ENOG4105CH2	amidohydrolase
CU254_40775	ENOG4105CSR	polyphosphate kinase 2
CU254_40825	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
CU254_40830	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
CU254_40835	ENOG41084GC	stage II sporulation protein
CU254_40890	ENOG4105DIM	ABC transporter
CU254_40895	ENOG4105CIG	ABC transporter
CU254_41025	ENOG4108QDA	dioxygenase
CU254_41045	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CU254_41070	ENOG4105DJV	ribulose-phosphate 3-epimerase
CU254_41100	ENOG4105ECY	inositol monophosphatase
CU254_41105	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CU254_41160	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CU254_41250	ENOG4105CJA	serine threonine protein kinase
CU254_41265	ENOG4107XZ0	Peptidase M50
CU254_41300	ENOG4105GVF	(ABC) transporter
CU254_41520	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CU254_41570	ENOG4107WCQ	Anion-transporting ATPase
CU254_41655	ENOG4105BZU	Histidine kinase
CU254_41735	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CU254_41920	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CU254_42090	ENOG4107SFI	Major Facilitator superfamily
CU254_42115	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CU254_42125	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
CU254_42135	ENOG4105CI0	Citrate lyase
CU254_42140	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CU254_42145	ENOG4105DJG	MaoC domain protein dehydratase
CU254_42150	ENOG4105FDP	GntR family transcriptional regulator
CU254_42155	ENOG4105D2S	major facilitator superfamily
CU254_42175	ENOG4105C0F	tryptophanase EC 4.1.99.1
CU254_42250	ENOG4105C0B	DNA polymerase III (alpha subunit)
CU254_42285	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CU254_42395	ENOG4107SIQ	Naphthoate synthase
CU254_42715	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)