locus-tag	class	description
BKN51_00430	COG2183	response to ionizing radiation
BKN51_00445	COG2072	flavoprotein involved in K transport
BKN51_00490	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_00490	COG2030	dehydratase
BKN51_00495	COG3396	Phenylacetate-CoA oxygenase
BKN51_00500	COG3460	Phenylacetate-CoA oxygenase
BKN51_00505	COG3396	Phenylacetate-CoA oxygenase
BKN51_00510	COG2151	metal-sulfur cluster biosynthetic enzyme
BKN51_00515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKN51_00520	COG0488	(ABC) transporter
BKN51_00530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKN51_00530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKN51_00545	COG1476	TRANSCRIPTIONal
BKN51_00555	COG1131	(ABC) transporter
BKN51_00580	COG2319	Wd-40 repeat
BKN51_00580	COG4249	Peptidase C14 caspase catalytic subunit p20
BKN51_00585	COG3973	AAA domain
BKN51_00625	COG1797	cobyrinic acid a,c-diamide synthase activity
BKN51_00640	COG0789	Transcriptional regulator
BKN51_00650	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BKN51_00655	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BKN51_00665	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BKN51_00670	COG1492	cobalamin metabolic process
BKN51_00675	COG0300	oxidoreductase activity
BKN51_00710	COG0070	glutamate synthase
BKN51_00710	COG0069	glutamate synthase activity
BKN51_00710	COG0067	glutamate synthase
BKN51_00715	COG1739	Uncharacterized protein family UPF0029
BKN51_00730	COG1522	sequence-specific DNA binding
BKN51_00745	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKN51_00750	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKN51_00755	COG0411	ABC transporter
BKN51_00760	COG0410	ABC transporter
BKN51_00765	COG2197	response regulator
BKN51_00775	COG0277	FAD linked oxidase domain protein
BKN51_00775	COG0247	lactate metabolic process
BKN51_00800	COG1309	transcriptional regulator
BKN51_00815	COG4552	Acetyltransferase involved in intracellular survival and related
BKN51_00830	COG0235	Class ii aldolase
BKN51_00830	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKN51_00840	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_00850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKN51_00855	COG0412	Dienelactone hydrolase
BKN51_00860	COG0010	Belongs to the arginase family
BKN51_00865	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BKN51_00870	COG3706	GGDEF domain
BKN51_00890	COG1796	DNA polymerase
BKN51_00890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKN51_00895	COG3268	Saccharopine dehydrogenase
BKN51_00920	COG0475	glutathione-regulated potassium exporter activity
BKN51_00930	COG1643	Atp-dependent helicase
BKN51_00940	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_00985	COG1024	Enoyl-CoA hydratase
BKN51_01030	COG1733	regulation of RNA biosynthetic process
BKN51_01065	COG0642	Histidine kinase
BKN51_01070	COG1136	(ABC) transporter
BKN51_01075	COG2884	Cell division ATP-binding protein ftsE
BKN51_01085	COG0745	RESPONSE REGULATOR receiver
BKN51_01090	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKN51_01105	COG1609	Transcriptional regulator
BKN51_01150	COG0596	Alpha beta hydrolase
BKN51_01165	COG1063	alcohol dehydrogenase
BKN51_01170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKN51_01175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKN51_01180	COG0581	inorganic phosphate transmembrane transporter activity
BKN51_01215	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_01250	COG2205	protein histidine kinase activity
BKN51_01255	COG0745	RESPONSE REGULATOR receiver
BKN51_01275	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BKN51_01285	COG4221	oxidoreductase activity
BKN51_01290	COG2267	carboxylic ester hydrolase activity
BKN51_01325	COG1937	Protein conserved in bacteria
BKN51_01330	COG3795	YCII-related domain
BKN51_01355	COG1733	regulation of RNA biosynthetic process
BKN51_01360	COG3629	intracellular signal transduction
BKN51_01375	COG4977	sequence-specific DNA binding
BKN51_01375	COG1917	Cupin 2, conserved barrel domain protein
BKN51_01430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKN51_01455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_01475	COG2197	response regulator
BKN51_01485	COG0009	L-threonylcarbamoyladenylate synthase
BKN51_01490	COG1733	regulation of RNA biosynthetic process
BKN51_01500	COG2197	response regulator
BKN51_01510	COG1917	Cupin 2, conserved barrel domain protein
BKN51_01510	COG4977	sequence-specific DNA binding
BKN51_01515	COG2197	response regulator
BKN51_01520	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKN51_01540	COG1793	dna ligase
BKN51_01540	COG3285	dna ligase
BKN51_01545	COG3285	dna ligase
BKN51_01545	COG1793	dna ligase
BKN51_01550	COG1846	Transcriptional regulator
BKN51_01560	COG1113	amino acid transport
BKN51_01570	COG1733	regulation of RNA biosynthetic process
BKN51_01590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKN51_01610	COG0745	RESPONSE REGULATOR receiver
BKN51_01615	COG2205	protein histidine kinase activity
BKN51_01625	COG1136	(ABC) transporter
BKN51_01625	COG0577	efflux transmembrane transporter activity
BKN51_01630	COG1136	(ABC) transporter
BKN51_01675	COG1609	Transcriptional regulator
BKN51_01715	COG2902	Dehydrogenase
BKN51_01755	COG0668	transmembrane transport
BKN51_01770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BKN51_01780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BKN51_01795	COG0698	ribose 5-phosphate isomerase
BKN51_01820	COG4941	Belongs to the sigma-70 factor family
BKN51_01835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKN51_01870	COG5002	protein histidine kinase activity
BKN51_01870	COG0784	Response regulator, receiver
BKN51_01885	COG0693	protein deglycase activity
BKN51_01900	COG2815	serine threonine protein kinase
BKN51_01900	COG0515	serine threonine protein kinase
BKN51_01925	COG2814	Major facilitator Superfamily
BKN51_01930	COG1846	Transcriptional regulator
BKN51_01935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKN51_01950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN51_01960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN51_01965	COG2205	protein histidine kinase activity
BKN51_01970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKN51_01975	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKN51_01985	COG0740	serine-type endopeptidase activity
BKN51_02020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKN51_02035	COG1316	TRANSCRIPTIONal
BKN51_02065	COG0525	valine-tRNA ligase activity
BKN51_02080	COG0285	dihydrofolate synthase activity
BKN51_02095	COG2366	antibiotic biosynthetic process
BKN51_02110	COG1733	regulation of RNA biosynthetic process
BKN51_02115	COG0105	UTP biosynthetic process
BKN51_02135	COG1131	(ABC) transporter
BKN51_02145	COG0842	Transport permease protein
BKN51_02155	COG1530	ribonuclease E activity
BKN51_02160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKN51_02165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKN51_02170	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKN51_02200	COG0018	arginyl-trna synthetase
BKN51_02205	COG0477	Major facilitator Superfamily
BKN51_02215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKN51_02220	COG0799	negative regulation of ribosome biogenesis
BKN51_02225	COG0406	alpha-ribazole phosphatase activity
BKN51_02235	COG1307	EDD domain protein, DegV family
BKN51_02245	COG0658	competence protein
BKN51_02245	COG2333	competence protein COMEC
BKN51_02260	COG0268	Binds directly to 16S ribosomal RNA
BKN51_02275	COG2226	methyltransferase
BKN51_02300	COG2070	2-Nitropropane dioxygenase
BKN51_02305	COG0531	amino acid
BKN51_02315	COG0604	alcohol dehydrogenase
BKN51_02330	COG2732	(Barnase) inhibitor
BKN51_02360	COG0175	sulfate reduction
BKN51_02395	COG2192	nodulation
BKN51_02405	COG0463	Glycosyl transferase, family 2
BKN51_02480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKN51_02490	COG1953	Uracil, thiamine, allantoin
BKN51_02495	COG0745	RESPONSE REGULATOR receiver
BKN51_02500	COG2205	protein histidine kinase activity
BKN51_02525	COG0667	Aldo Keto reductase
BKN51_02530	COG1420	regulation of RNA biosynthetic process
BKN51_02535	COG0484	heat shock protein binding
BKN51_02545	COG0537	adenosine 5'-monophosphoramidase activity
BKN51_02555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKN51_02570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKN51_02605	COG1381	Involved in DNA repair and RecF pathway recombination
BKN51_02610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKN51_02620	COG0701	Predicted permease
BKN51_02655	COG0423	glycine-tRNA ligase activity
BKN51_02660	COG1131	(ABC) transporter
BKN51_02670	COG4585	Histidine kinase
BKN51_02675	COG2197	response regulator
BKN51_02685	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BKN51_02700	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_02705	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKN51_02710	COG1595	DNA-templated transcription, initiation
BKN51_02725	COG4106	trans-aconitate 2-methyltransferase activity
BKN51_02760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKN51_02795	COG0531	amino acid
BKN51_02805	COG3903	Transcriptional regulator
BKN51_02805	COG3629	intracellular signal transduction
BKN51_02810	COG0464	growth
BKN51_02815	COG1404	Belongs to the peptidase S8 family
BKN51_02825	COG1674	ftsk spoiiie
BKN51_02895	COG3629	intracellular signal transduction
BKN51_02895	COG3903	Transcriptional regulator
BKN51_02900	COG3629	intracellular signal transduction
BKN51_02900	COG3903	Transcriptional regulator
BKN51_02920	COG3647	Membrane
BKN51_02945	COG0477	Major facilitator Superfamily
BKN51_02960	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_02980	COG2508	Transcriptional regulator
BKN51_02985	COG2072	flavoprotein involved in K transport
BKN51_02990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKN51_03010	COG2223	nitrite transmembrane transporter activity
BKN51_03015	COG2207	Transcriptional regulator
BKN51_03025	COG3629	intracellular signal transduction
BKN51_03025	COG3903	Transcriptional regulator
BKN51_03045	COG2133	pyrroloquinoline quinone binding
BKN51_03050	COG4585	Histidine kinase
BKN51_03060	COG2197	response regulator
BKN51_03075	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_03085	COG0137	argininosuccinate synthase activity
BKN51_03150	COG3850	Histidine kinase
BKN51_03150	COG5002	protein histidine kinase activity
BKN51_03200	COG0823	Involved in the tonB-independent uptake of proteins
BKN51_03200	COG1506	peptidase
BKN51_03200	COG4946	Tricorn protease homolog
BKN51_03205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKN51_03205	COG2022	thiamine diphosphate biosynthetic process
BKN51_03225	COG0187	DNA topoisomerase II activity
BKN51_03260	COG0842	Transport permease protein
BKN51_03260	COG1131	(ABC) transporter
BKN51_03260	COG1716	ATPase activity
BKN51_03315	COG0346	lactoylglutathione lyase activity
BKN51_03325	COG2186	Transcriptional regulator
BKN51_03345	COG1309	transcriptional regulator
BKN51_03360	COG1335	isochorismatase
BKN51_03370	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BKN51_03395	COG2814	Major facilitator Superfamily
BKN51_03400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKN51_03415	COG3903	Transcriptional regulator
BKN51_03415	COG3629	intracellular signal transduction
BKN51_03450	COG1309	transcriptional regulator
BKN51_03470	COG2267	carboxylic ester hydrolase activity
BKN51_03480	COG3629	intracellular signal transduction
BKN51_03480	COG3903	Transcriptional regulator
BKN51_03540	COG1316	TRANSCRIPTIONal
BKN51_03555	COG1960	acyl-CoA dehydrogenase activity
BKN51_03560	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN51_03570	COG1024	Enoyl-CoA hydratase
BKN51_03575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKN51_03580	COG0583	DNA-binding transcription factor activity
BKN51_03585	COG5002	protein histidine kinase activity
BKN51_03590	COG0745	RESPONSE REGULATOR receiver
BKN51_03600	COG2936	dipeptidyl-peptidase activity
BKN51_03610	COG1733	regulation of RNA biosynthetic process
BKN51_03615	COG2197	response regulator
BKN51_03635	COG1309	transcriptional regulator
BKN51_03670	COG0779	Required for maturation of 30S ribosomal subunits
BKN51_03690	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKN51_03720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BKN51_03735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKN51_03755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKN51_03760	COG1185	polyribonucleotide nucleotidyltransferase activity
BKN51_03765	COG0612	Peptidase, M16
BKN51_03770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKN51_03790	COG3214	Protein conserved in bacteria
BKN51_03820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKN51_03825	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKN51_03840	COG1113	amino acid transport
BKN51_03850	COG5006	permease, DMT superfamily
BKN51_03880	COG1674	ftsk spoiiie
BKN51_03890	COG0596	Alpha beta hydrolase
BKN51_03900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKN51_03905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKN51_03915	COG1546	Belongs to the CinA family
BKN51_03915	COG1058	Belongs to the CinA family
BKN51_03920	COG1396	sequence-specific DNA binding
BKN51_03945	COG0154	amidase activity
BKN51_03950	COG0167	dihydroorotate dehydrogenase activity
BKN51_03960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKN51_03965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKN51_03970	COG1192	Involved in chromosome partitioning
BKN51_03975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKN51_03980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKN51_03990	COG1305	Transglutaminase-like
BKN51_04000	COG0714	Associated with various cellular activities
BKN51_04025	COG2001	Belongs to the MraZ family
BKN51_04030	COG0275	rRNA processing
BKN51_04040	COG0768	penicillin binding
BKN51_04055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKN51_04060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKN51_04070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKN51_04075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKN51_04080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKN51_04120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_04170	COG0697	spore germination
BKN51_04205	COG0242	peptide deformylase activity
BKN51_04210	COG1201	RNA secondary structure unwinding
BKN51_04215	COG0443	Heat shock 70 kDa protein
BKN51_04225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKN51_04230	COG2137	regulation of response to DNA damage stimulus
BKN51_04250	COG0800	Aldolase
BKN51_04270	COG1053	succinate dehydrogenase
BKN51_04280	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_04300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKN51_04305	COG0765	amino acid transport
BKN51_04310	COG0765	amino acid transport
BKN51_04315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN51_04320	COG1126	abc transporter atp-binding protein
BKN51_04325	COG0745	RESPONSE REGULATOR receiver
BKN51_04330	COG2205	protein histidine kinase activity
BKN51_04340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKN51_04350	COG1196	nuclear chromosome segregation
BKN51_04360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKN51_04380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKN51_04390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKN51_04400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKN51_04440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKN51_04445	COG2076	Multidrug Resistance protein
BKN51_04450	COG1505	serine-type exopeptidase activity
BKN51_04470	COG3387	PFAM Glycoside hydrolase 15-related
BKN51_04485	COG0628	permease
BKN51_04500	COG2936	dipeptidyl-peptidase activity
BKN51_04520	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BKN51_04535	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKN51_04555	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_04560	COG1960	acyl-CoA dehydrogenase activity
BKN51_04565	COG1960	acyl-CoA dehydrogenase activity
BKN51_04575	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_04585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKN51_04590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKN51_04640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_04650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_04675	COG0003	Pfam Anion-transporting ATPase
BKN51_04685	COG1940	carbohydrate kinase activity
BKN51_04695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKN51_04720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKN51_04730	COG1228	amidohydrolase
BKN51_04765	COG1946	Acyl-CoA thioesterase
BKN51_04785	COG1672	PFAM Archaeal ATPase
BKN51_04785	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKN51_04790	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_04810	COG1960	acyl-CoA dehydrogenase activity
BKN51_04815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKN51_04825	COG1024	Enoyl-CoA hydratase
BKN51_04845	COG2814	Major facilitator Superfamily
BKN51_04855	COG1309	transcriptional regulator
BKN51_04860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN51_04875	COG2018	Roadblock/LC7 domain
BKN51_04890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKN51_04905	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BKN51_04905	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BKN51_04905	COG1703	isobutyryl-CoA mutase activity
BKN51_04910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_04915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_04920	COG1309	transcriptional regulator
BKN51_04925	COG1960	acyl-CoA dehydrogenase activity
BKN51_04930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKN51_04950	COG1960	acyl-CoA dehydrogenase activity
BKN51_04955	COG1960	acyl-CoA dehydrogenase activity
BKN51_04980	COG0196	riboflavin kinase activity
BKN51_05010	COG1053	succinate dehydrogenase
BKN51_05020	COG1960	acyl-CoA dehydrogenase activity
BKN51_05025	COG2267	carboxylic ester hydrolase activity
BKN51_05030	COG0346	lactoylglutathione lyase activity
BKN51_05035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKN51_05060	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_05085	COG1960	acyl-CoA dehydrogenase activity
BKN51_05090	COG1960	acyl-CoA dehydrogenase activity
BKN51_05095	COG1960	acyl-CoA dehydrogenase activity
BKN51_05100	COG1024	Enoyl-CoA hydratase
BKN51_05105	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_05110	COG1960	acyl-CoA dehydrogenase activity
BKN51_05115	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_05120	COG1309	transcriptional regulator
BKN51_05125	COG0183	Belongs to the thiolase family
BKN51_05130	COG2814	Major facilitator Superfamily
BKN51_05140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKN51_05180	COG0110	maltose O-acetyltransferase activity
BKN51_05195	COG0596	Alpha beta hydrolase
BKN51_05215	COG1024	Enoyl-CoA hydratase
BKN51_05220	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_05225	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_05245	COG0183	Belongs to the thiolase family
BKN51_05250	COG2124	cytochrome p450
BKN51_05260	COG1295	ribonuclease BN
BKN51_05285	COG1024	Enoyl-CoA hydratase
BKN51_05295	COG2070	2-Nitropropane dioxygenase
BKN51_05305	COG2188	Transcriptional regulator
BKN51_05310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKN51_05315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKN51_05350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BKN51_05350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BKN51_05365	COG2890	protein-(glutamine-N5) methyltransferase activity
BKN51_05385	COG2313	pseudouridylate synthase activity
BKN51_05410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKN51_05425	COG4213	ABC transporter substrate-binding protein
BKN51_05435	COG4214	carbohydrate transport
BKN51_05450	COG0596	Alpha beta hydrolase
BKN51_05470	COG0531	amino acid
BKN51_05475	COG2197	response regulator
BKN51_05500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKN51_05525	COG0483	inositol monophosphate 1-phosphatase activity
BKN51_05545	COG0756	dUTP diphosphatase activity
BKN51_05575	COG0569	domain protein
BKN51_05580	COG0531	amino acid
BKN51_05585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKN51_05605	COG3851	Histidine kinase
BKN51_05610	COG2197	response regulator
BKN51_05630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BKN51_05645	COG1309	transcriptional regulator
BKN51_05650	COG0300	oxidoreductase activity
BKN51_05660	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_05665	COG0028	Belongs to the TPP enzyme family
BKN51_05675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN51_05685	COG0745	RESPONSE REGULATOR receiver
BKN51_05690	COG2205	protein histidine kinase activity
BKN51_05695	COG0656	L-ascorbic acid biosynthetic process
BKN51_05715	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN51_05715	COG1024	Enoyl-CoA hydratase
BKN51_05720	COG0183	Belongs to the thiolase family
BKN51_05750	COG0531	amino acid
BKN51_05765	COG2197	response regulator
BKN51_05775	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKN51_05790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKN51_05800	COG3220	belongs to the UPF0276 family
BKN51_05820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKN51_05830	COG2815	serine threonine protein kinase
BKN51_05830	COG0515	serine threonine protein kinase
BKN51_05840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN51_05850	COG0477	Major facilitator Superfamily
BKN51_05870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_05875	COG0539	negative regulation of cytoplasmic translation
BKN51_05880	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BKN51_05880	COG2508	Transcriptional regulator
BKN51_05885	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_05890	COG0506	proline dehydrogenase activity
BKN51_05895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN51_05910	COG1793	dna ligase
BKN51_05955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKN51_05970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKN51_05975	COG2326	polyphosphate kinase activity
BKN51_05990	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKN51_06000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKN51_06005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKN51_06030	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKN51_06075	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BKN51_06085	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKN51_06090	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BKN51_06095	COG0235	Class ii aldolase
BKN51_06100	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BKN51_06135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKN51_06150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKN51_06155	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BKN51_06165	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_06195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKN51_06205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN51_06210	COG1263	PTS System
BKN51_06210	COG2190	(PTS) system
BKN51_06210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN51_06220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN51_06220	COG1263	PTS System
BKN51_06255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKN51_06260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKN51_06270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKN51_06275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKN51_06280	COG0346	lactoylglutathione lyase activity
BKN51_06295	COG0006	proline dipeptidase activity
BKN51_06300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKN51_06305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKN51_06315	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BKN51_06320	COG0540	Belongs to the ATCase OTCase family
BKN51_06335	COG0505	Belongs to the CarA family
BKN51_06345	COG0284	orotidine-5'-phosphate decarboxylase activity
BKN51_06355	COG0194	GDP metabolic process
BKN51_06360	COG1758	RNA polymerase activity
BKN51_06370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKN51_06375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKN51_06385	COG0405	Gamma-glutamyltransferase
BKN51_06390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKN51_06415	COG2197	response regulator
BKN51_06420	COG4585	Histidine kinase
BKN51_06435	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKN51_06435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKN51_06440	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKN51_06460	COG0322	excinuclease ABC activity
BKN51_06465	COG1660	Displays ATPase and GTPase activities
BKN51_06475	COG1481	regulation of sporulation
BKN51_06495	COG1309	transcriptional regulator
BKN51_06510	COG3250	beta-galactosidase activity
BKN51_06575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKN51_06580	COG0126	phosphoglycerate kinase activity
BKN51_06585	COG0149	triose-phosphate isomerase activity
BKN51_06605	COG0363	glucosamine-6-phosphate deaminase activity
BKN51_06620	COG0166	Belongs to the GPI family
BKN51_06625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKN51_06635	COG0109	protoheme IX farnesyltransferase activity
BKN51_06680	COG1612	heme a metabolic process
BKN51_06715	COG0396	ATPase activity
BKN51_06730	COG2151	metal-sulfur cluster biosynthetic enzyme
BKN51_06735	COG1742	UPF0060 membrane protein
BKN51_06745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKN51_06760	COG4585	Histidine kinase
BKN51_06765	COG2197	response regulator
BKN51_06780	COG0175	sulfate reduction
BKN51_06800	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_06810	COG2200	EAL domain
BKN51_06810	COG2199	diguanylate cyclase activity
BKN51_06815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_06820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BKN51_06835	COG0488	(ABC) transporter
BKN51_06850	COG1132	(ABC) transporter
BKN51_06860	COG4821	SIS domain
BKN51_06870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKN51_06875	COG1316	TRANSCRIPTIONal
BKN51_06900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKN51_06905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKN51_06910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKN51_06910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKN51_06920	COG1024	Enoyl-CoA hydratase
BKN51_06965	COG1960	acyl-CoA dehydrogenase activity
BKN51_06970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKN51_06990	COG1309	transcriptional regulator
BKN51_07015	COG3469	chitinase activity
BKN51_07020	COG0745	RESPONSE REGULATOR receiver
BKN51_07020	COG3706	GGDEF domain
BKN51_07035	COG0477	Major facilitator Superfamily
BKN51_07045	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_07095	COG0477	Major facilitator Superfamily
BKN51_07115	COG0604	alcohol dehydrogenase
BKN51_07115	COG3321	synthase
BKN51_07155	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN51_07165	COG1960	acyl-CoA dehydrogenase activity
BKN51_07180	COG2091	lysine biosynthetic process via aminoadipic acid
BKN51_07210	COG1309	transcriptional regulator
BKN51_07220	COG1960	acyl-CoA dehydrogenase activity
BKN51_07225	COG1960	acyl-CoA dehydrogenase activity
BKN51_07230	COG1960	acyl-CoA dehydrogenase activity
BKN51_07250	COG1404	Belongs to the peptidase S8 family
BKN51_07255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BKN51_07260	COG0717	Belongs to the dCTP deaminase family
BKN51_07280	COG4106	trans-aconitate 2-methyltransferase activity
BKN51_07295	COG0484	heat shock protein binding
BKN51_07315	COG0531	amino acid
BKN51_07320	COG1940	carbohydrate kinase activity
BKN51_07345	COG2124	cytochrome p450
BKN51_07400	COG1846	Transcriptional regulator
BKN51_07430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_07435	COG0477	Major facilitator Superfamily
BKN51_07445	COG1793	dna ligase
BKN51_07465	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BKN51_07485	COG0739	heme binding
BKN51_07500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKN51_07500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN51_07515	COG2814	Major facilitator Superfamily
BKN51_07520	COG2855	membrane
BKN51_07535	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_07535	COG0604	alcohol dehydrogenase
BKN51_07535	COG3321	synthase
BKN51_07540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKN51_07550	COG1819	glycosyl
BKN51_07560	COG0439	Biotin carboxylase
BKN51_07575	COG3706	GGDEF domain
BKN51_07600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKN51_07605	COG0328	RNA-DNA hybrid ribonuclease activity
BKN51_07620	COG2205	protein histidine kinase activity
BKN51_07625	COG0745	RESPONSE REGULATOR receiver
BKN51_07635	COG3706	GGDEF domain
BKN51_07645	COG3903	Transcriptional regulator
BKN51_07645	COG3629	intracellular signal transduction
BKN51_07650	COG0697	spore germination
BKN51_07670	COG1309	transcriptional regulator
BKN51_07690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_07710	COG1733	regulation of RNA biosynthetic process
BKN51_07720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_07725	COG1053	succinate dehydrogenase
BKN51_07735	COG1414	Transcriptional regulator
BKN51_07740	COG2815	serine threonine protein kinase
BKN51_07740	COG0515	serine threonine protein kinase
BKN51_07750	COG2124	cytochrome p450
BKN51_07760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN51_07765	COG1733	regulation of RNA biosynthetic process
BKN51_07770	COG1309	transcriptional regulator
BKN51_07775	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_07810	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_07830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_07880	COG0459	protein refolding
BKN51_07885	COG3655	Transcriptional regulator
BKN51_07930	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_07955	COG0438	transferase activity, transferring glycosyl groups
BKN51_07965	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKN51_07970	COG0723	plastoquinol--plastocyanin reductase activity
BKN51_07975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKN51_07980	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKN51_08010	COG3903	Transcriptional regulator
BKN51_08010	COG3629	intracellular signal transduction
BKN51_08085	COG1335	isochorismatase
BKN51_08105	COG0483	inositol monophosphate 1-phosphatase activity
BKN51_08115	COG3629	intracellular signal transduction
BKN51_08115	COG3903	Transcriptional regulator
BKN51_08120	COG1073	alpha beta
BKN51_08150	COG3046	protein related to deoxyribodipyrimidine photolyase
BKN51_08170	COG0596	Alpha beta hydrolase
BKN51_08200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_08220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN51_08235	COG0154	amidase activity
BKN51_08240	COG2197	response regulator
BKN51_08250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKN51_08260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKN51_08305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKN51_08315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKN51_08385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKN51_08400	COG0288	reversible hydration of carbon dioxide
BKN51_08415	COG2197	response regulator
BKN51_08425	COG1309	transcriptional regulator
BKN51_08440	COG0747	negative chemotaxis
BKN51_08445	COG4172	Belongs to the ABC transporter superfamily
BKN51_08450	COG0667	Aldo Keto reductase
BKN51_08460	COG0477	Major facilitator Superfamily
BKN51_08475	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BKN51_08485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_08510	COG0367	asparagine synthase
BKN51_08530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN51_08535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKN51_08540	COG1280	lysine exporter protein (LysE YggA)
BKN51_08550	COG1733	regulation of RNA biosynthetic process
BKN51_08555	COG0702	epimerase
BKN51_08560	COG3345	alpha-galactosidase
BKN51_08575	COG1846	Transcriptional regulator
BKN51_08580	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BKN51_08590	COG1177	transmembrane transport
BKN51_08595	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKN51_08610	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_08620	COG2070	2-Nitropropane dioxygenase
BKN51_08625	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_08630	COG1024	Enoyl-CoA hydratase
BKN51_08640	COG1024	Enoyl-CoA hydratase
BKN51_08645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKN51_08655	COG2271	Major facilitator Superfamily
BKN51_08660	COG2233	PERMEase
BKN51_08670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_08675	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_08695	COG2197	response regulator
BKN51_08715	COG1404	Belongs to the peptidase S8 family
BKN51_08755	COG1733	regulation of RNA biosynthetic process
BKN51_08770	COG2814	Major facilitator Superfamily
BKN51_08785	COG0745	RESPONSE REGULATOR receiver
BKN51_08790	COG2205	protein histidine kinase activity
BKN51_08800	COG2755	lipolytic protein G-D-S-L family
BKN51_08800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKN51_08805	COG2197	response regulator
BKN51_08900	COG2197	response regulator
BKN51_08910	COG4249	Peptidase C14 caspase catalytic subunit p20
BKN51_08910	COG2319	Wd-40 repeat
BKN51_08970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_08985	COG0477	Major facilitator Superfamily
BKN51_08995	COG0596	Alpha beta hydrolase
BKN51_09005	COG3629	intracellular signal transduction
BKN51_09005	COG3903	Transcriptional regulator
BKN51_09010	COG3321	synthase
BKN51_09010	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_09010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_09010	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_09010	COG0300	oxidoreductase activity
BKN51_09060	COG2197	response regulator
BKN51_09115	COG2261	transglycosylase associated protein
BKN51_09145	COG2814	Major facilitator Superfamily
BKN51_09150	COG1984	allophanate hydrolase subunit 2
BKN51_09160	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKN51_09165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKN51_09190	COG0789	Transcriptional regulator
BKN51_09195	COG2197	response regulator
BKN51_09220	COG2197	response regulator
BKN51_09235	COG1819	glycosyl
BKN51_09290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_09295	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN51_09305	COG1960	acyl-CoA dehydrogenase activity
BKN51_09320	COG0604	alcohol dehydrogenase
BKN51_09320	COG3321	synthase
BKN51_09325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_09345	COG2124	cytochrome p450
BKN51_09365	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_09410	COG2124	cytochrome p450
BKN51_09420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKN51_09465	COG1309	transcriptional regulator
BKN51_09470	COG2130	NADP-dependent
BKN51_09570	COG0778	Nitroreductase
BKN51_09575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKN51_09600	COG1560	Kdo2-lipid A biosynthetic process
BKN51_09605	COG0438	transferase activity, transferring glycosyl groups
BKN51_09615	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKN51_09615	COG3608	succinylglutamate desuccinylase aspartoacylase
BKN51_09625	COG0277	FAD linked oxidase domain protein
BKN51_09630	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BKN51_09650	COG0242	peptide deformylase activity
BKN51_09655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_09670	COG1672	PFAM Archaeal ATPase
BKN51_09670	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKN51_09690	COG3903	Transcriptional regulator
BKN51_09690	COG3629	intracellular signal transduction
BKN51_09700	COG1309	transcriptional regulator
BKN51_09725	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BKN51_09730	COG0217	transcriptional regulatory protein
BKN51_09745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BKN51_09750	COG0632	four-way junction helicase activity
BKN51_09760	COG1862	Preprotein translocase
BKN51_09770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKN51_09775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKN51_09780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKN51_09785	COG1024	Enoyl-CoA hydratase
BKN51_09800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKN51_09805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN51_09830	COG3629	intracellular signal transduction
BKN51_09830	COG3903	Transcriptional regulator
BKN51_09880	COG2018	Roadblock/LC7 domain
BKN51_09900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKN51_09910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKN51_09935	COG1280	lysine exporter protein (LysE YggA)
BKN51_09955	COG0596	Alpha beta hydrolase
BKN51_09965	COG3622	Belongs to the hyi family
BKN51_09970	COG2084	Dehydrogenase
BKN51_09975	COG3960	tartronate-semialdehyde synthase activity
BKN51_09995	COG2366	antibiotic biosynthetic process
BKN51_10005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKN51_10035	COG1793	dna ligase
BKN51_10035	COG3285	dna ligase
BKN51_10040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKN51_10045	COG1522	sequence-specific DNA binding
BKN51_10065	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BKN51_10140	COG0778	Nitroreductase
BKN51_10140	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BKN51_10165	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_10185	COG0302	gtp cyclohydrolase
BKN51_10195	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKN51_10200	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_10215	COG1309	transcriptional regulator
BKN51_10220	COG4106	trans-aconitate 2-methyltransferase activity
BKN51_10235	COG0488	(ABC) transporter
BKN51_10245	COG0395	ABC-type sugar transport system, permease component
BKN51_10265	COG1609	Transcriptional regulator
BKN51_10280	COG2160	L-arabinose isomerase activity
BKN51_10285	COG4213	ABC transporter substrate-binding protein
BKN51_10290	COG1129	ABC transporter
BKN51_10295	COG4214	carbohydrate transport
BKN51_10300	COG3250	beta-galactosidase activity
BKN51_10365	COG4977	sequence-specific DNA binding
BKN51_10380	COG1733	regulation of RNA biosynthetic process
BKN51_10395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_10405	COG1253	flavin adenine dinucleotide binding
BKN51_10410	COG0129	dihydroxy-acid dehydratase activity
BKN51_10445	COG4585	Histidine kinase
BKN51_10450	COG2197	response regulator
BKN51_10475	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN51_10500	COG0583	DNA-binding transcription factor activity
BKN51_10505	COG0006	proline dipeptidase activity
BKN51_10535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKN51_10540	COG3938	Belongs to the proline racemase family
BKN51_10550	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKN51_10560	COG0477	Major facilitator Superfamily
BKN51_10605	COG3103	Sh3 type 3 domain protein
BKN51_10605	COG1388	LysM domain
BKN51_10605	COG0791	NLP P60 protein
BKN51_10615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN51_10655	COG0601	transmembrane transport
BKN51_10660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKN51_10665	COG0444	Belongs to the ABC transporter superfamily
BKN51_10670	COG4608	Belongs to the ABC transporter superfamily
BKN51_10675	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BKN51_10680	COG3835	regulator
BKN51_10690	COG4948	Mandelate Racemase Muconate Lactonizing
BKN51_10795	COG1024	Enoyl-CoA hydratase
BKN51_10805	COG0488	(ABC) transporter
BKN51_10810	COG0395	ABC-type sugar transport system, permease component
BKN51_10840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKN51_10855	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_10860	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BKN51_10865	COG1132	(ABC) transporter
BKN51_10875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_10880	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_10895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN51_10945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_10975	COG0640	Transcriptional regulator
BKN51_10995	COG0523	cobalamin synthesis protein
BKN51_11005	COG0254	rRNA binding
BKN51_11015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKN51_11020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKN51_11025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKN51_11030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKN51_11040	COG1648	precorrin-2 dehydrogenase activity
BKN51_11040	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKN51_11055	COG1024	Enoyl-CoA hydratase
BKN51_11060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKN51_11075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKN51_11125	COG0509	glycine decarboxylation via glycine cleavage system
BKN51_11130	COG1716	ATPase activity
BKN51_11155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKN51_11155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKN51_11170	COG0656	L-ascorbic acid biosynthetic process
BKN51_11220	COG2267	carboxylic ester hydrolase activity
BKN51_11230	COG0583	DNA-binding transcription factor activity
BKN51_11240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKN51_11245	COG0121	glutamine amidotransferase
BKN51_11250	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BKN51_11275	COG0477	Major facilitator Superfamily
BKN51_11280	COG0583	DNA-binding transcription factor activity
BKN51_11295	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKN51_11300	COG3883	PFAM NLP P60 protein
BKN51_11300	COG0791	NLP P60 protein
BKN51_11305	COG0746	molybdenum cofactor guanylyltransferase activity
BKN51_11315	COG0714	Associated with various cellular activities
BKN51_11325	COG2304	oxidoreductase activity
BKN51_11330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKN51_11335	COG3540	Alkaline phosphatase
BKN51_11355	COG2205	protein histidine kinase activity
BKN51_11365	COG0477	Major facilitator Superfamily
BKN51_11375	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKN51_11400	COG3226	Transcriptional regulator
BKN51_11405	COG0596	Alpha beta hydrolase
BKN51_11420	COG2197	response regulator
BKN51_11425	COG4585	Histidine kinase
BKN51_11435	COG4867	von Willebrand factor, type A
BKN51_11445	COG0789	Transcriptional regulator
BKN51_11450	COG0215	cysteine-tRNA ligase activity
BKN51_11455	COG0488	(ABC) transporter
BKN51_11460	COG1846	Transcriptional regulator
BKN51_11470	COG2814	Major facilitator Superfamily
BKN51_11500	COG0140	phosphoribosyl-ATP diphosphatase activity
BKN51_11505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKN51_11510	COG1192	Involved in chromosome partitioning
BKN51_11525	COG0517	IMP dehydrogenase activity
BKN51_11525	COG1994	Peptidase M50
BKN51_11545	COG1222	aaa ATPase
BKN51_11575	COG1051	belongs to the nudix hydrolase family
BKN51_11590	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BKN51_11595	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BKN51_11615	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BKN51_11625	COG0640	Transcriptional regulator
BKN51_11650	COG1733	regulation of RNA biosynthetic process
BKN51_11660	COG2378	regulation of single-species biofilm formation
BKN51_11670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKN51_11680	COG1597	lipid kinase activity
BKN51_11710	COG4552	Acetyltransferase involved in intracellular survival and related
BKN51_11765	COG0667	Aldo Keto reductase
BKN51_11775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_11790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN51_11795	COG2362	D-Aminopeptidase
BKN51_11805	COG0488	(ABC) transporter
BKN51_11825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKN51_11835	COG1595	DNA-templated transcription, initiation
BKN51_11850	COG0183	Belongs to the thiolase family
BKN51_11855	COG1733	regulation of RNA biosynthetic process
BKN51_11895	COG0601	transmembrane transport
BKN51_11925	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKN51_11970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN51_11985	COG0477	Major facilitator Superfamily
BKN51_12005	COG0640	Transcriptional regulator
BKN51_12010	COG1309	transcriptional regulator
BKN51_12035	COG0235	Class ii aldolase
BKN51_12040	COG3395	kinase activity
BKN51_12050	COG3622	Belongs to the hyi family
BKN51_12055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKN51_12065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_12070	COG0300	oxidoreductase activity
BKN51_12080	COG0596	Alpha beta hydrolase
BKN51_12100	COG4974	Belongs to the 'phage' integrase family
BKN51_12110	COG0590	tRNA wobble adenosine to inosine editing
BKN51_12120	COG1522	sequence-specific DNA binding
BKN51_12125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_12150	COG2080	2 iron, 2 sulfur cluster binding
BKN51_12155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKN51_12160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKN51_12200	COG2197	response regulator
BKN51_12205	COG4585	Histidine kinase
BKN51_12220	COG3268	Saccharopine dehydrogenase
BKN51_12235	COG0789	Transcriptional regulator
BKN51_12240	COG0477	Major facilitator Superfamily
BKN51_12330	COG2197	response regulator
BKN51_12335	COG4585	Histidine kinase
BKN51_12365	COG0778	Nitroreductase
BKN51_12410	COG1509	lysine 2,3-aminomutase activity
BKN51_12420	COG1228	amidohydrolase
BKN51_12430	COG0463	Glycosyl transferase, family 2
BKN51_12450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKN51_12460	COG1435	thymidine kinase activity
BKN51_12485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKN51_12495	COG2226	methyltransferase
BKN51_12500	COG2226	methyltransferase
BKN51_12505	COG2890	protein-(glutamine-N5) methyltransferase activity
BKN51_12515	COG2318	DinB family
BKN51_12520	COG1595	DNA-templated transcription, initiation
BKN51_12530	COG1309	transcriptional regulator
BKN51_12535	COG1960	acyl-CoA dehydrogenase activity
BKN51_12565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKN51_12615	COG0702	epimerase
BKN51_12630	COG4221	oxidoreductase activity
BKN51_12635	COG1357	PFAM Pentapeptide repeats (8 copies)
BKN51_12645	COG2755	lipolytic protein G-D-S-L family
BKN51_12685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKN51_12870	COG1309	transcriptional regulator
BKN51_12875	COG2226	methyltransferase
BKN51_12900	COG2226	methyltransferase
BKN51_12915	COG0702	epimerase
BKN51_12930	COG1309	transcriptional regulator
BKN51_12950	COG0028	Belongs to the TPP enzyme family
BKN51_12985	COG0024	Methionine aminopeptidase
BKN51_13060	COG1136	(ABC) transporter
BKN51_13060	COG0577	efflux transmembrane transporter activity
BKN51_13095	COG4521	taurine ABC transporter
BKN51_13100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKN51_13115	COG2318	DinB family
BKN51_13180	COG0387	Pfam Sodium calcium exchanger
BKN51_13185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKN51_13195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKN51_13200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKN51_13200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKN51_13205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKN51_13240	COG1309	transcriptional regulator
BKN51_13250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKN51_13270	COG0697	spore germination
BKN51_13280	COG2084	Dehydrogenase
BKN51_13300	COG1136	(ABC) transporter
BKN51_13305	COG1136	(ABC) transporter
BKN51_13315	COG3537	Alpha-1,2-mannosidase
BKN51_13320	COG0477	Major facilitator Superfamily
BKN51_13330	COG1595	DNA-templated transcription, initiation
BKN51_13360	COG0039	L-malate dehydrogenase activity
BKN51_13370	COG0789	Transcriptional regulator
BKN51_13390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKN51_13430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_13435	COG1104	cysteine desulfurase activity
BKN51_13440	COG0339	signal peptide processing
BKN51_13450	COG1968	undecaprenyl-diphosphatase activity
BKN51_13455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_13460	COG0667	Aldo Keto reductase
BKN51_13490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN51_13495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN51_13610	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_13635	COG3404	Formiminotransferase-cyclodeaminase
BKN51_13640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKN51_13760	COG2115	Belongs to the xylose isomerase family
BKN51_13765	COG1940	carbohydrate kinase activity
BKN51_13795	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKN51_13830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_13860	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKN51_13865	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKN51_13870	COG1129	ABC transporter
BKN51_13875	COG1879	ABC-type sugar transport system periplasmic component
BKN51_13880	COG1609	Transcriptional regulator
BKN51_13885	COG4585	Histidine kinase
BKN51_13890	COG2197	response regulator
BKN51_13915	COG2197	response regulator
BKN51_13920	COG4585	Histidine kinase
BKN51_13935	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BKN51_13980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BKN51_13990	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BKN51_14005	COG0298	carbon dioxide binding
BKN51_14045	COG1136	(ABC) transporter
BKN51_14050	COG3629	intracellular signal transduction
BKN51_14050	COG3903	Transcriptional regulator
BKN51_14085	COG2197	response regulator
BKN51_14090	COG1404	Belongs to the peptidase S8 family
BKN51_14110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKN51_14135	COG4608	Belongs to the ABC transporter superfamily
BKN51_14140	COG0444	Belongs to the ABC transporter superfamily
BKN51_14150	COG4166	transmembrane transport
BKN51_14180	COG4948	Mandelate Racemase Muconate Lactonizing
BKN51_14195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKN51_14205	COG0395	ABC-type sugar transport system, permease component
BKN51_14210	COG1175	transmembrane transport
BKN51_14240	COG1132	(ABC) transporter
BKN51_14255	COG3629	intracellular signal transduction
BKN51_14270	COG1733	regulation of RNA biosynthetic process
BKN51_14290	COG0477	Major facilitator Superfamily
BKN51_14295	COG2755	lipolytic protein G-D-S-L family
BKN51_14295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKN51_14300	COG5002	protein histidine kinase activity
BKN51_14305	COG0745	RESPONSE REGULATOR receiver
BKN51_14315	COG0702	epimerase
BKN51_14320	COG1846	Transcriptional regulator
BKN51_14325	COG2409	Drug exporters of the RND superfamily
BKN51_14365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKN51_14375	COG1609	Transcriptional regulator
BKN51_14390	COG0601	transmembrane transport
BKN51_14395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKN51_14450	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKN51_14485	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BKN51_14515	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BKN51_14540	COG0477	Major facilitator Superfamily
BKN51_14555	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_14565	COG3971	2-oxopent-4-enoate hydratase activity
BKN51_14620	COG0747	negative chemotaxis
BKN51_14625	COG0601	transmembrane transport
BKN51_14645	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_14650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKN51_14675	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_14680	COG1802	Transcriptional regulator
BKN51_14695	COG5504	Zn-dependent protease
BKN51_14760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKN51_14775	COG1120	ATPase activity
BKN51_14780	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_14785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_14790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN51_14795	COG2375	cellular response to nickel ion
BKN51_14800	COG1535	isochorismatase
BKN51_14800	COG3433	isochorismatase activity
BKN51_14805	COG3433	isochorismatase activity
BKN51_14805	COG1535	isochorismatase
BKN51_14810	COG1021	2,3-dihydroxybenzoate-AMP ligase
BKN51_14815	COG1169	isochorismate synthase
BKN51_14820	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_14830	COG2205	protein histidine kinase activity
BKN51_14835	COG0745	RESPONSE REGULATOR receiver
BKN51_14850	COG4977	sequence-specific DNA binding
BKN51_14860	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_14870	COG2186	Transcriptional regulator
BKN51_14880	COG0277	FAD linked oxidase domain protein
BKN51_14885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKN51_14890	COG1414	Transcriptional regulator
BKN51_14910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKN51_14920	COG0477	Major facilitator Superfamily
BKN51_14955	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BKN51_14960	COG4139	cobalamin transport
BKN51_14975	COG1609	Transcriptional regulator
BKN51_14985	COG1175	transmembrane transport
BKN51_14995	COG0366	Alpha amylase catalytic
BKN51_15000	COG3903	Transcriptional regulator
BKN51_15000	COG3629	intracellular signal transduction
BKN51_15005	COG1764	response to oxidative stress
BKN51_15030	COG0583	DNA-binding transcription factor activity
BKN51_15070	COG4209	transmembrane transport
BKN51_15075	COG0395	ABC-type sugar transport system, permease component
BKN51_15090	COG1609	Transcriptional regulator
BKN51_15105	COG2815	serine threonine protein kinase
BKN51_15105	COG0515	serine threonine protein kinase
BKN51_15110	COG1609	Transcriptional regulator
BKN51_15150	COG0277	FAD linked oxidase domain protein
BKN51_15175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKN51_15180	COG2079	MmgE PrpD family protein
BKN51_15200	COG1960	acyl-CoA dehydrogenase activity
BKN51_15225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKN51_15255	COG3226	Transcriptional regulator
BKN51_15275	COG0714	Associated with various cellular activities
BKN51_15280	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BKN51_15315	COG0673	inositol 2-dehydrogenase activity
BKN51_15370	COG3903	Transcriptional regulator
BKN51_15370	COG3629	intracellular signal transduction
BKN51_15375	COG1132	(ABC) transporter
BKN51_15380	COG1132	(ABC) transporter
BKN51_15385	COG1309	transcriptional regulator
BKN51_15455	COG2814	Major facilitator Superfamily
BKN51_15500	COG0583	DNA-binding transcription factor activity
BKN51_15510	COG2132	Multicopper oxidase
BKN51_15520	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKN51_15525	COG0277	FAD linked oxidase domain protein
BKN51_15525	COG0247	lactate metabolic process
BKN51_15530	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKN51_15565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKN51_15575	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_15605	COG2326	polyphosphate kinase activity
BKN51_15645	COG0745	RESPONSE REGULATOR receiver
BKN51_15650	COG2205	protein histidine kinase activity
BKN51_15665	COG4221	oxidoreductase activity
BKN51_15675	COG0640	Transcriptional regulator
BKN51_15750	COG2124	cytochrome p450
BKN51_15780	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKN51_15820	COG2197	response regulator
BKN51_15830	COG0583	DNA-binding transcription factor activity
BKN51_15845	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKN51_15860	COG3291	Pkd domain containing protein
BKN51_15860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BKN51_15865	COG4948	Mandelate Racemase Muconate Lactonizing
BKN51_15880	COG0667	Aldo Keto reductase
BKN51_15905	COG3268	Saccharopine dehydrogenase
BKN51_15910	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_15915	COG1522	sequence-specific DNA binding
BKN51_15920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BKN51_15925	COG0477	Major facilitator Superfamily
BKN51_15930	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_15935	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BKN51_15945	COG1960	acyl-CoA dehydrogenase activity
BKN51_15960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_16075	COG2319	Wd-40 repeat
BKN51_16075	COG4249	Peptidase C14 caspase catalytic subunit p20
BKN51_16215	COG4585	Histidine kinase
BKN51_16220	COG2197	response regulator
BKN51_16225	COG0596	Alpha beta hydrolase
BKN51_16235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKN51_16280	COG0148	phosphopyruvate hydratase activity
BKN51_16285	COG0025	NhaP-type Na H and K H
BKN51_16340	COG1522	sequence-specific DNA binding
BKN51_16350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKN51_16375	COG0488	(ABC) transporter
BKN51_16400	COG2815	serine threonine protein kinase
BKN51_16400	COG0515	serine threonine protein kinase
BKN51_16420	COG0784	Response regulator, receiver
BKN51_16425	COG4251	negative regulation of phosphorylation
BKN51_16430	COG0745	RESPONSE REGULATOR receiver
BKN51_16450	COG1819	glycosyl
BKN51_16455	COG0300	oxidoreductase activity
BKN51_16470	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_16475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_16475	COG3321	synthase
BKN51_16480	COG0477	Major facilitator Superfamily
BKN51_16495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKN51_16495	COG0515	serine threonine protein kinase
BKN51_16500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKN51_16500	COG0515	serine threonine protein kinase
BKN51_16575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKN51_16600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKN51_16630	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_16645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKN51_16660	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_16665	COG0667	Aldo Keto reductase
BKN51_16670	COG3226	Transcriptional regulator
BKN51_16680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_16720	COG0477	Major facilitator Superfamily
BKN51_16725	COG1959	2 iron, 2 sulfur cluster binding
BKN51_16740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKN51_16750	COG1414	Transcriptional regulator
BKN51_16755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKN51_16780	COG3511	phospholipase C
BKN51_16790	COG1335	isochorismatase
BKN51_16805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKN51_16810	COG2755	lipolytic protein G-D-S-L family
BKN51_16810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKN51_16815	COG2318	DinB family
BKN51_16825	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_16865	COG0583	DNA-binding transcription factor activity
BKN51_16870	COG2814	Major facilitator Superfamily
BKN51_16875	COG2076	Multidrug Resistance protein
BKN51_16885	COG0583	DNA-binding transcription factor activity
BKN51_16900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKN51_16900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKN51_16910	COG1309	transcriptional regulator
BKN51_16955	COG2197	response regulator
BKN51_16975	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_17000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKN51_17010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKN51_17030	COG0861	Integral membrane protein TerC family
BKN51_17045	COG1063	alcohol dehydrogenase
BKN51_17070	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN51_17075	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN51_17080	COG2172	sigma factor antagonist activity
BKN51_17100	COG1132	(ABC) transporter
BKN51_17105	COG1309	transcriptional regulator
BKN51_17120	COG1064	alcohol dehydrogenase
BKN51_17145	COG5002	protein histidine kinase activity
BKN51_17150	COG0745	RESPONSE REGULATOR receiver
BKN51_17155	COG1136	(ABC) transporter
BKN51_17155	COG0577	efflux transmembrane transporter activity
BKN51_17160	COG4591	ABC-type transport system involved in lipoprotein release permease component
BKN51_17180	COG0515	serine threonine protein kinase
BKN51_17180	COG2815	serine threonine protein kinase
BKN51_17190	COG2409	Drug exporters of the RND superfamily
BKN51_17195	COG1309	transcriptional regulator
BKN51_17215	COG3629	intracellular signal transduction
BKN51_17215	COG3903	Transcriptional regulator
BKN51_17220	COG2197	response regulator
BKN51_17225	COG4585	Histidine kinase
BKN51_17230	COG2315	Protein conserved in bacteria
BKN51_17245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKN51_17250	COG0028	Belongs to the TPP enzyme family
BKN51_17285	COG3903	Transcriptional regulator
BKN51_17285	COG3629	intracellular signal transduction
BKN51_17290	COG0596	Alpha beta hydrolase
BKN51_17320	COG4991	sh3 domain protein
BKN51_17340	COG0500	methyltransferase
BKN51_17380	COG4981	capsule polysaccharide biosynthetic process
BKN51_17400	COG5001	Diguanylate cyclase
BKN51_17425	COG3903	Transcriptional regulator
BKN51_17425	COG3629	intracellular signal transduction
BKN51_17435	COG0596	Alpha beta hydrolase
BKN51_17455	COG4948	Mandelate Racemase Muconate Lactonizing
BKN51_17460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKN51_17470	COG1414	Transcriptional regulator
BKN51_17475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKN51_17480	COG3973	AAA domain
BKN51_17485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKN51_17515	COG1160	GTP binding
BKN51_17545	COG0475	glutathione-regulated potassium exporter activity
BKN51_17550	COG2936	dipeptidyl-peptidase activity
BKN51_17560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKN51_17595	COG0504	CTP synthase activity
BKN51_17600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKN51_17610	COG1802	Transcriptional regulator
BKN51_17630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKN51_17645	COG0647	UMP catabolic process
BKN51_17670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKN51_17675	COG2094	Belongs to the DNA glycosylase MPG family
BKN51_17705	COG0165	Argininosuccinate lyase
BKN51_17710	COG0137	argininosuccinate synthase activity
BKN51_17715	COG1438	arginine binding
BKN51_17720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKN51_17725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKN51_17730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKN51_17735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BKN51_17740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKN51_17770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN51_17770	COG0072	phenylalanine-tRNA ligase activity
BKN51_17775	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKN51_17785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKN51_17790	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKN51_17795	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKN51_17810	COG1802	Transcriptional regulator
BKN51_17820	COG0251	oxidation-reduction process
BKN51_17840	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BKN51_17845	COG2610	gluconate transmembrane transporter activity
BKN51_17850	COG2706	6-phosphogluconolactonase activity
BKN51_17870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BKN51_17880	COG1403	HNH endonuclease
BKN51_17910	COG4565	transcriptional regulatory protein
BKN51_17915	COG3290	protein histidine kinase activity
BKN51_17920	COG1301	dicarboxylic acid transport
BKN51_17930	COG1733	regulation of RNA biosynthetic process
BKN51_17975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN51_18045	COG3012	SEC-C Motif Domain Protein
BKN51_18055	COG3250	beta-galactosidase activity
BKN51_18090	COG1070	Carbohydrate kinase
BKN51_18095	COG1609	Transcriptional regulator
BKN51_18110	COG0823	Involved in the tonB-independent uptake of proteins
BKN51_18110	COG4946	Tricorn protease homolog
BKN51_18110	COG1506	peptidase
BKN51_18120	COG1131	(ABC) transporter
BKN51_18135	COG1024	Enoyl-CoA hydratase
BKN51_18170	COG0237	dephospho-CoA kinase activity
BKN51_18170	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BKN51_18180	COG0539	negative regulation of cytoplasmic translation
BKN51_18185	COG2226	methyltransferase
BKN51_18205	COG1511	domain protein
BKN51_18220	COG1653	transport
BKN51_18255	COG0583	DNA-binding transcription factor activity
BKN51_18300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKN51_18305	COG1501	Belongs to the glycosyl hydrolase 31 family
BKN51_18310	COG1349	DNA-binding transcription factor activity
BKN51_18325	COG0395	ABC-type sugar transport system, permease component
BKN51_18330	COG3833	ABC-type maltose transport systems, permease component
BKN51_18350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKN51_18370	COG0187	DNA topoisomerase II activity
BKN51_18380	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_18390	COG2188	Transcriptional regulator
BKN51_18410	COG2066	Belongs to the glutaminase family
BKN51_18420	COG0583	DNA-binding transcription factor activity
BKN51_18445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKN51_18490	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN51_18505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_18510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_18525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_18530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_18535	COG1132	(ABC) transporter
BKN51_18540	COG1132	(ABC) transporter
BKN51_18550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKN51_18560	COG3845	ABC transporter
BKN51_18620	COG0411	ABC transporter
BKN51_18625	COG0410	ABC transporter
BKN51_18630	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKN51_18685	COG4941	Belongs to the sigma-70 factor family
BKN51_18715	COG2124	cytochrome p450
BKN51_18725	COG5001	Diguanylate cyclase
BKN51_18735	COG2124	cytochrome p450
BKN51_18795	COG1846	Transcriptional regulator
BKN51_18820	COG0515	serine threonine protein kinase
BKN51_18825	COG0740	serine-type endopeptidase activity
BKN51_18830	COG0740	serine-type endopeptidase activity
BKN51_18855	COG3237	CsbD-like
BKN51_18890	COG1140	nitrate reductase beta subunit
BKN51_18940	COG2197	response regulator
BKN51_18950	COG3903	Transcriptional regulator
BKN51_18950	COG3629	intracellular signal transduction
BKN51_18980	COG1349	DNA-binding transcription factor activity
BKN51_19010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKN51_19020	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKN51_19030	COG0463	Glycosyl transferase, family 2
BKN51_19035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKN51_19045	COG2124	cytochrome p450
BKN51_19100	COG0789	Transcriptional regulator
BKN51_19125	COG2318	DinB family
BKN51_19140	COG2197	response regulator
BKN51_19150	COG1131	(ABC) transporter
BKN51_19160	COG0596	Alpha beta hydrolase
BKN51_19200	COG2197	response regulator
BKN51_19205	COG2197	response regulator
BKN51_19210	COG3629	intracellular signal transduction
BKN51_19210	COG3903	Transcriptional regulator
BKN51_19225	COG2197	response regulator
BKN51_19235	COG0583	DNA-binding transcription factor activity
BKN51_19310	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_19340	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_19385	COG0798	PFAM Bile acid sodium symporter
BKN51_19420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_19430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN51_19430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN51_19455	COG0277	FAD linked oxidase domain protein
BKN51_19465	COG1834	amidinotransferase
BKN51_19475	COG0596	Alpha beta hydrolase
BKN51_19480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_19495	COG2197	response regulator
BKN51_19500	COG4585	Histidine kinase
BKN51_19530	COG2197	response regulator
BKN51_19535	COG4585	Histidine kinase
BKN51_19555	COG2072	flavoprotein involved in K transport
BKN51_19580	COG1120	ATPase activity
BKN51_19585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_19635	COG1309	transcriptional regulator
BKN51_19645	COG2356	endonuclease I
BKN51_19665	COG2197	response regulator
BKN51_19670	COG4585	Histidine kinase
BKN51_19695	COG1136	(ABC) transporter
BKN51_19725	COG0402	S-adenosylhomocysteine deaminase activity
BKN51_19745	COG2319	Wd-40 repeat
BKN51_19745	COG4249	Peptidase C14 caspase catalytic subunit p20
BKN51_19755	COG2807	transmembrane transport
BKN51_19760	COG2186	Transcriptional regulator
BKN51_19820	COG2197	response regulator
BKN51_19880	COG0477	Major facilitator Superfamily
BKN51_19885	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_19895	COG2814	Major facilitator Superfamily
BKN51_19930	COG0693	protein deglycase activity
BKN51_19930	COG0753	catalase activity
BKN51_19940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKN51_19945	COG0463	Glycosyl transferase, family 2
BKN51_19970	COG0714	Associated with various cellular activities
BKN51_19975	COG2205	protein histidine kinase activity
BKN51_19980	COG0745	RESPONSE REGULATOR receiver
BKN51_19985	COG0745	RESPONSE REGULATOR receiver
BKN51_20040	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_20075	COG1902	pentaerythritol trinitrate reductase activity
BKN51_20110	COG1595	DNA-templated transcription, initiation
BKN51_20115	COG2815	serine threonine protein kinase
BKN51_20115	COG0515	serine threonine protein kinase
BKN51_20200	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKN51_20205	COG1335	isochorismatase
BKN51_20210	COG0473	3-isopropylmalate dehydrogenase activity
BKN51_20225	COG2508	Transcriptional regulator
BKN51_20230	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BKN51_20275	COG0596	Alpha beta hydrolase
BKN51_20280	COG2208	phosphoserine phosphatase activity
BKN51_20280	COG2770	Histidine kinase
BKN51_20290	COG0367	asparagine synthase
BKN51_20310	COG0492	ferredoxin-NADP+ reductase activity
BKN51_20345	COG2201	protein-glutamate methylesterase activity
BKN51_20390	COG3546	catalase activity
BKN51_20405	COG0723	plastoquinol--plastocyanin reductase activity
BKN51_20410	COG4221	oxidoreductase activity
BKN51_20440	COG1595	DNA-templated transcription, initiation
BKN51_20470	COG0583	DNA-binding transcription factor activity
BKN51_20500	COG3629	intracellular signal transduction
BKN51_20500	COG3903	Transcriptional regulator
BKN51_20515	COG2197	response regulator
BKN51_20525	COG3629	intracellular signal transduction
BKN51_20525	COG3903	Transcriptional regulator
BKN51_20600	COG1674	ftsk spoiiie
BKN51_20615	COG1404	Belongs to the peptidase S8 family
BKN51_20625	COG0464	growth
BKN51_20645	COG3953	SLT domain
BKN51_20645	COG5280	Phage tail tape measure protein TP901
BKN51_20665	COG1278	Cold shock
BKN51_20680	COG3835	regulator
BKN51_20710	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKN51_20730	COG0436	Aminotransferase
BKN51_20910	COG2192	nodulation
BKN51_20915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKN51_20930	COG3340	Belongs to the peptidase S51 family
BKN51_20940	COG1518	maintenance of DNA repeat elements
BKN51_20955	COG1857	crispr-associated protein
BKN51_21050	COG1785	Belongs to the alkaline phosphatase family
BKN51_21055	COG2197	response regulator
BKN51_21060	COG4585	Histidine kinase
BKN51_21070	COG1302	Protein conserved in bacteria
BKN51_21105	COG1595	DNA-templated transcription, initiation
BKN51_21125	COG0596	Alpha beta hydrolase
BKN51_21135	COG1280	lysine exporter protein (LysE YggA)
BKN51_21145	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKN51_21150	COG3903	Transcriptional regulator
BKN51_21150	COG3629	intracellular signal transduction
BKN51_21180	COG0640	Transcriptional regulator
BKN51_21195	COG0596	Alpha beta hydrolase
BKN51_21250	COG0640	Transcriptional regulator
BKN51_21260	COG0514	ATP-dependent DNA helicase (RecQ)
BKN51_21270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKN51_21285	COG0542	response to heat
BKN51_21290	COG0477	Major facilitator Superfamily
BKN51_21300	COG0667	Aldo Keto reductase
BKN51_21315	COG1309	transcriptional regulator
BKN51_21325	COG0667	Aldo Keto reductase
BKN51_21340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKN51_21340	COG2010	Cytochrome c
BKN51_21355	COG1940	carbohydrate kinase activity
BKN51_21380	COG1309	transcriptional regulator
BKN51_21405	COG0248	Ppx GppA phosphatase
BKN51_21410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_21415	COG2226	methyltransferase
BKN51_21435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKN51_21460	COG0640	Transcriptional regulator
BKN51_21470	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKN51_21495	COG3599	regulation of cell shape
BKN51_21505	COG1799	cell septum assembly
BKN51_21510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BKN51_21530	COG1595	DNA-templated transcription, initiation
BKN51_21545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKN51_21555	COG2318	DinB family
BKN51_21565	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BKN51_21580	COG0596	Alpha beta hydrolase
BKN51_21590	COG0067	glutamate synthase
BKN51_21590	COG0069	glutamate synthase activity
BKN51_21590	COG0070	glutamate synthase
BKN51_21600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKN51_21615	COG0174	glutamine synthetase
BKN51_21620	COG0159	tryptophan synthase activity
BKN51_21625	COG0133	tryptophan synthase activity
BKN51_21630	COG0134	indole-3-glycerol-phosphate synthase activity
BKN51_21640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKN51_21675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKN51_21685	COG0107	imidazoleglycerol-phosphate synthase activity
BKN51_21690	COG1309	transcriptional regulator
BKN51_21750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKN51_21755	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKN51_21765	COG1960	acyl-CoA dehydrogenase activity
BKN51_21780	COG3958	Transketolase
BKN51_21785	COG3959	Transketolase, thiamine diphosphate binding domain
BKN51_21795	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BKN51_21805	COG1309	transcriptional regulator
BKN51_21810	COG2409	Drug exporters of the RND superfamily
BKN51_21815	COG0131	Imidazoleglycerol-phosphate dehydratase
BKN51_21820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKN51_21825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKN51_21835	COG1522	sequence-specific DNA binding
BKN51_21840	COG3386	PFAM SMP-30 Gluconolaconase
BKN51_21845	COG2197	response regulator
BKN51_21895	COG1674	ftsk spoiiie
BKN51_21905	COG3896	Chloramphenicol phosphotransferase-like protein
BKN51_21960	COG1404	Belongs to the peptidase S8 family
BKN51_21970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKN51_21975	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKN51_22005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BKN51_22010	COG0659	secondary active sulfate transmembrane transporter activity
BKN51_22015	COG0659	secondary active sulfate transmembrane transporter activity
BKN51_22020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKN51_22025	COG2124	cytochrome p450
BKN51_22040	COG0438	transferase activity, transferring glycosyl groups
BKN51_22105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKN51_22115	COG2010	Cytochrome c
BKN51_22120	COG1845	cytochrome c oxidase, subunit III
BKN51_22145	COG1917	Cupin 2, conserved barrel domain protein
BKN51_22165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKN51_22200	COG0667	Aldo Keto reductase
BKN51_22210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKN51_22225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKN51_22235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKN51_22300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKN51_22330	COG0321	lipoyl(octanoyl) transferase activity
BKN51_22345	COG1309	transcriptional regulator
BKN51_22355	COG4221	oxidoreductase activity
BKN51_22360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKN51_22365	COG0586	Pfam SNARE associated Golgi protein
BKN51_22370	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKN51_22380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKN51_22410	COG0477	Major facilitator Superfamily
BKN51_22415	COG0587	DNA-directed DNA polymerase activity
BKN51_22435	COG1113	amino acid transport
BKN51_22455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKN51_22475	COG3226	Transcriptional regulator
BKN51_22480	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_22505	COG0154	amidase activity
BKN51_22525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BKN51_22535	COG3201	nicotinamide mononucleotide transporter
BKN51_22540	COG0668	transmembrane transport
BKN51_22550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKN51_22555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKN51_22570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKN51_22590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKN51_22600	COG0095	Lipoate-protein ligase
BKN51_22605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BKN51_22610	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BKN51_22615	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BKN51_22645	COG2197	response regulator
BKN51_22655	COG1396	sequence-specific DNA binding
BKN51_22685	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BKN51_22695	COG0442	prolyl-tRNA aminoacylation
BKN51_22720	COG3022	response to hydroperoxide
BKN51_22740	COG1404	Belongs to the peptidase S8 family
BKN51_22760	COG0513	Belongs to the DEAD box helicase family
BKN51_22795	COG2807	transmembrane transport
BKN51_22800	COG2186	Transcriptional regulator
BKN51_22815	COG0454	-acetyltransferase
BKN51_22815	COG0456	acetyltransferase
BKN51_22820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKN51_22825	COG0750	zinc metalloprotease
BKN51_22830	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BKN51_22845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKN51_22860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_22895	COG1476	TRANSCRIPTIONal
BKN51_22905	COG3540	Alkaline phosphatase
BKN51_22915	COG2267	carboxylic ester hydrolase activity
BKN51_22995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKN51_23000	COG1695	Transcriptional regulator
BKN51_23015	COG2272	Belongs to the type-B carboxylesterase lipase family
BKN51_23030	COG0528	UMP kinase activity
BKN51_23035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKN51_23040	COG0052	Belongs to the universal ribosomal protein uS2 family
BKN51_23050	COG1191	sigma factor activity
BKN51_23065	COG0606	chelatase, subunit chli
BKN51_23070	COG0792	nuclease activity
BKN51_23080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKN51_23085	COG0681	Belongs to the peptidase S26 family
BKN51_23090	COG0335	large ribosomal subunit rRNA binding
BKN51_23095	COG0336	Belongs to the RNA methyltransferase TrmD family
BKN51_23100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKN51_23110	COG0228	four-way junction DNA binding
BKN51_23140	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKN51_23150	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BKN51_23210	COG1832	CoA-binding protein
BKN51_23220	COG4266	Belongs to the allantoicase family
BKN51_23225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKN51_23240	COG2351	hydroxyisourate hydrolase activity
BKN51_23250	COG0596	Alpha beta hydrolase
BKN51_23260	COG1309	transcriptional regulator
BKN51_23275	COG2252	PERMEase
BKN51_23280	COG0590	tRNA wobble adenosine to inosine editing
BKN51_23285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKN51_23305	COG3835	regulator
BKN51_23325	COG0596	Alpha beta hydrolase
BKN51_23360	COG1414	Transcriptional regulator
BKN51_23370	COG0477	Major facilitator Superfamily
BKN51_23380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BKN51_23395	COG1254	Belongs to the acylphosphatase family
BKN51_23415	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BKN51_23420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BKN51_23425	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BKN51_23435	COG0367	asparagine synthase
BKN51_23450	COG1131	(ABC) transporter
BKN51_23455	COG1725	Transcriptional regulator
BKN51_23470	COG0673	inositol 2-dehydrogenase activity
BKN51_23480	COG1082	Xylose isomerase domain protein TIM barrel
BKN51_23490	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKN51_23500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKN51_23505	COG3718	enzyme involved in inositol metabolism
BKN51_23510	COG3962	Belongs to the TPP enzyme family
BKN51_23530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_23570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKN51_23575	COG1522	sequence-specific DNA binding
BKN51_23605	COG0667	Aldo Keto reductase
BKN51_23620	COG1414	Transcriptional regulator
BKN51_23625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKN51_23630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKN51_23635	COG3485	protocatechuate 3,4-dioxygenase
BKN51_23640	COG3485	protocatechuate 3,4-dioxygenase
BKN51_23650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKN51_23655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BKN51_23665	COG1929	Belongs to the glycerate kinase type-1 family
BKN51_23710	COG2186	Transcriptional regulator
BKN51_23715	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKN51_23720	COG1129	ABC transporter
BKN51_23735	COG4948	Mandelate Racemase Muconate Lactonizing
BKN51_23740	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKN51_23745	COG2814	Major facilitator Superfamily
BKN51_23760	COG4221	oxidoreductase activity
BKN51_23770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_23775	COG1120	ATPase activity
BKN51_23790	COG2186	Transcriptional regulator
BKN51_23795	COG1760	l-serine dehydratase
BKN51_23800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKN51_23805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKN51_23810	COG0509	glycine decarboxylation via glycine cleavage system
BKN51_23815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKN51_23820	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKN51_23820	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKN51_23835	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_23840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKN51_23845	COG0174	glutamine synthetase
BKN51_23855	COG0017	Asparaginyl-tRNA synthetase
BKN51_23865	COG1672	PFAM Archaeal ATPase
BKN51_23865	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKN51_23870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN51_23890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_23895	COG1131	(ABC) transporter
BKN51_23925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKN51_23930	COG0571	ribonuclease III activity
BKN51_23935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKN51_23965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKN51_23970	COG0742	ribosomal rna small subunit methyltransferase
BKN51_23975	COG3973	AAA domain
BKN51_23980	COG4249	Peptidase C14 caspase catalytic subunit p20
BKN51_23980	COG2319	Wd-40 repeat
BKN51_23985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_23995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKN51_24020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKN51_24065	COG3835	regulator
BKN51_24075	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKN51_24080	COG1404	Belongs to the peptidase S8 family
BKN51_24100	COG0456	acetyltransferase
BKN51_24120	COG1461	Dihydroxyacetone kinase
BKN51_24125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKN51_24130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKN51_24135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKN51_24165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_24175	COG2205	protein histidine kinase activity
BKN51_24180	COG0745	RESPONSE REGULATOR receiver
BKN51_24205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKN51_24210	COG0252	asparaginase activity
BKN51_24220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKN51_24245	COG0776	regulation of translation
BKN51_24250	COG0066	3-isopropylmalate dehydratase activity
BKN51_24255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKN51_24260	COG1414	Transcriptional regulator
BKN51_24290	COG1674	ftsk spoiiie
BKN51_24310	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKN51_24340	COG0745	RESPONSE REGULATOR receiver
BKN51_24345	COG0464	growth
BKN51_24355	COG0745	RESPONSE REGULATOR receiver
BKN51_24360	COG2205	protein histidine kinase activity
BKN51_24390	COG0714	Associated with various cellular activities
BKN51_24450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN51_24455	COG0019	diaminopimelate decarboxylase activity
BKN51_24465	COG1116	anion transmembrane transporter activity
BKN51_24475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKN51_24480	COG0601	transmembrane transport
BKN51_24485	COG0747	negative chemotaxis
BKN51_24495	COG0583	DNA-binding transcription factor activity
BKN51_24545	COG4585	Histidine kinase
BKN51_24550	COG2197	response regulator
BKN51_24570	COG0596	Alpha beta hydrolase
BKN51_24580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKN51_24590	COG1309	transcriptional regulator
BKN51_24615	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKN51_24620	COG3629	intracellular signal transduction
BKN51_24620	COG3903	Transcriptional regulator
BKN51_24640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKN51_24645	COG0473	3-isopropylmalate dehydrogenase activity
BKN51_24650	COG1404	Belongs to the peptidase S8 family
BKN51_24690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKN51_24695	COG0440	acetolactate synthase activity
BKN51_24710	COG0129	dihydroxy-acid dehydratase activity
BKN51_24765	COG0154	amidase activity
BKN51_24770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKN51_24785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKN51_24805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN51_24810	COG0456	acetyltransferase
BKN51_24815	COG0482	sulfurtransferase activity
BKN51_24825	COG0477	Major facilitator Superfamily
BKN51_24830	COG2909	trisaccharide binding
BKN51_24850	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKN51_24860	COG1307	EDD domain protein, DegV family
BKN51_24870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKN51_24880	COG0386	Belongs to the glutathione peroxidase family
BKN51_24940	COG0110	maltose O-acetyltransferase activity
BKN51_24950	COG3883	PFAM NLP P60 protein
BKN51_24950	COG0791	NLP P60 protein
BKN51_24955	COG0542	response to heat
BKN51_24960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_24970	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BKN51_24995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKN51_25075	COG2226	methyltransferase
BKN51_25080	COG1024	Enoyl-CoA hydratase
BKN51_25085	COG1119	ATPase activity
BKN51_25095	COG2897	thiosulfate sulfurtransferase activity
BKN51_25105	COG0058	SHG alpha-glucan phosphorylase activity
BKN51_25130	COG1846	Transcriptional regulator
BKN51_25140	COG3537	Alpha-1,2-mannosidase
BKN51_25145	COG1609	Transcriptional regulator
BKN51_25160	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKN51_25175	COG3275	phosphorelay sensor kinase activity
BKN51_25180	COG3279	Response regulator of the LytR AlgR family
BKN51_25190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN51_25200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN51_25205	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKN51_25210	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKN51_25215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_25245	COG0183	Belongs to the thiolase family
BKN51_25280	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKN51_25285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKN51_25295	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BKN51_25300	COG2226	methyltransferase
BKN51_25310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKN51_25320	COG0433	COG0433 Predicted ATPase
BKN51_25325	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BKN51_25355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKN51_25355	COG1017	nitric oxide dioxygenase activity
BKN51_25360	COG2423	ornithine cyclodeaminase activity
BKN51_25365	COG2031	fatty acid transporter
BKN51_25445	COG1024	Enoyl-CoA hydratase
BKN51_25465	COG0673	inositol 2-dehydrogenase activity
BKN51_25475	COG2814	Major facilitator Superfamily
BKN51_25485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKN51_25520	COG0698	ribose 5-phosphate isomerase
BKN51_25530	COG3469	chitinase activity
BKN51_25540	COG1595	DNA-templated transcription, initiation
BKN51_25545	COG1278	Cold shock
BKN51_25575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKN51_25585	COG1408	metallophosphoesterase
BKN51_25625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKN51_25635	COG2259	Doxx family
BKN51_25640	COG2259	Doxx family
BKN51_25655	COG2018	Roadblock/LC7 domain
BKN51_25675	COG3844	kynureninase activity
BKN51_25690	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_25700	COG3706	GGDEF domain
BKN51_25710	COG1316	TRANSCRIPTIONal
BKN51_25825	COG0587	DNA-directed DNA polymerase activity
BKN51_25880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKN51_25885	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKN51_25895	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKN51_25910	COG1794	racemase activity, acting on amino acids and derivatives
BKN51_25940	COG3191	aminopeptidase activity
BKN51_25955	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BKN51_25960	COG1335	isochorismatase
BKN51_25965	COG0800	Aldolase
BKN51_25975	COG1268	BioY protein
BKN51_26010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKN51_26020	COG1819	glycosyl
BKN51_26025	COG2267	carboxylic ester hydrolase activity
BKN51_26045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKN51_26070	COG0626	cystathionine gamma-synthase activity
BKN51_26075	COG1522	sequence-specific DNA binding
BKN51_26100	COG1461	Dihydroxyacetone kinase
BKN51_26105	COG2376	Dihydroxyacetone kinase
BKN51_26135	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKN51_26140	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BKN51_26155	COG4977	sequence-specific DNA binding
BKN51_26165	COG1126	abc transporter atp-binding protein
BKN51_26170	COG0765	amino acid transport
BKN51_26175	COG0765	amino acid transport
BKN51_26180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN51_26205	COG1280	lysine exporter protein (LysE YggA)
BKN51_26210	COG1280	lysine exporter protein (LysE YggA)
BKN51_26215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKN51_26230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKN51_26240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKN51_26245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKN51_26250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKN51_26255	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKN51_26260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKN51_26265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKN51_26270	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKN51_26275	COG0356	it plays a direct role in the translocation of protons across the membrane
BKN51_26285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKN51_26300	COG2890	protein-(glutamine-N5) methyltransferase activity
BKN51_26305	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BKN51_26315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN51_26350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKN51_26355	COG0254	rRNA binding
BKN51_26365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKN51_26375	COG0083	homoserine kinase activity
BKN51_26380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKN51_26385	COG0460	homoserine dehydrogenase
BKN51_26390	COG0019	diaminopimelate decarboxylase activity
BKN51_26395	COG0018	arginyl-trna synthetase
BKN51_26415	COG0596	Alpha beta hydrolase
BKN51_26440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_26445	COG2124	cytochrome p450
BKN51_26460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKN51_26465	COG0022	dehydrogenase e1 component
BKN51_26475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKN51_26530	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_26535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKN51_26540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN51_26550	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BKN51_26555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_26560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKN51_26570	COG1053	succinate dehydrogenase
BKN51_26585	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKN51_26605	COG4941	Belongs to the sigma-70 factor family
BKN51_26620	COG1846	Transcriptional regulator
BKN51_26635	COG2910	NAD(P)H-binding
BKN51_26660	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_26685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKN51_26690	COG3345	alpha-galactosidase
BKN51_26725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKN51_26730	COG0435	Glutathione S-transferase
BKN51_26740	COG2133	pyrroloquinoline quinone binding
BKN51_26750	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BKN51_26770	COG0667	Aldo Keto reductase
BKN51_26785	COG0154	amidase activity
BKN51_26815	COG0473	3-isopropylmalate dehydrogenase activity
BKN51_26840	COG3903	Transcriptional regulator
BKN51_26840	COG3629	intracellular signal transduction
BKN51_26855	COG0028	Belongs to the TPP enzyme family
BKN51_26860	COG0477	Major facilitator Superfamily
BKN51_26880	COG4585	Histidine kinase
BKN51_26885	COG2197	response regulator
BKN51_26890	COG2409	Drug exporters of the RND superfamily
BKN51_26900	COG1132	(ABC) transporter
BKN51_26915	COG1024	Enoyl-CoA hydratase
BKN51_26915	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN51_26920	COG0183	Belongs to the thiolase family
BKN51_26935	COG1960	acyl-CoA dehydrogenase activity
BKN51_26940	COG1960	acyl-CoA dehydrogenase activity
BKN51_26955	COG4221	oxidoreductase activity
BKN51_26965	COG1960	acyl-CoA dehydrogenase activity
BKN51_26975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKN51_26980	COG2755	lipolytic protein G-D-S-L family
BKN51_26995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKN51_27005	COG0346	lactoylglutathione lyase activity
BKN51_27010	COG1695	Transcriptional regulator
BKN51_27020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BKN51_27020	COG2508	Transcriptional regulator
BKN51_27040	COG0686	Belongs to the AlaDH PNT family
BKN51_27055	COG1132	(ABC) transporter
BKN51_27075	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKN51_27075	COG0567	Dehydrogenase, E1 component
BKN51_27095	COG3153	acetyltransferase
BKN51_27105	COG1174	glycine betaine transport
BKN51_27110	COG1174	glycine betaine transport
BKN51_27115	COG0517	IMP dehydrogenase activity
BKN51_27115	COG1125	glycine betaine transport
BKN51_27130	COG0281	malic enzyme
BKN51_27135	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BKN51_27155	COG0406	alpha-ribazole phosphatase activity
BKN51_27170	COG1597	lipid kinase activity
BKN51_27195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKN51_27210	COG2135	peptidase activity
BKN51_27215	COG1162	GTPase activity
BKN51_27255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKN51_27260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKN51_27270	COG0653	protein targeting
BKN51_27275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKN51_27290	COG5002	protein histidine kinase activity
BKN51_27290	COG5000	phosphorelay sensor kinase activity
BKN51_27295	COG0745	RESPONSE REGULATOR receiver
BKN51_27300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKN51_27305	COG2146	nitrite reductase [NAD(P)H] activity
BKN51_27310	COG1414	Transcriptional regulator
BKN51_27320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKN51_27325	COG4638	Rieske (2fe-2S)
BKN51_27350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKN51_27365	COG0531	amino acid
BKN51_27375	COG3629	intracellular signal transduction
BKN51_27375	COG3903	Transcriptional regulator
BKN51_27380	COG1482	cell wall glycoprotein biosynthetic process
BKN51_27390	COG2835	tetraacyldisaccharide 4'-kinase activity
BKN51_27410	COG3547	Transposase (IS116 IS110 IS902 family)
BKN51_27425	COG1994	Peptidase M50
BKN51_27440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKN51_27460	COG0601	transmembrane transport
BKN51_27470	COG0747	negative chemotaxis
BKN51_27485	COG0180	Tryptophanyl-tRNA synthetase
BKN51_27495	COG2205	protein histidine kinase activity
BKN51_27510	COG1131	(ABC) transporter
BKN51_27520	COG3842	ATPase activity
BKN51_27525	COG4149	molybdate abc transporter
BKN51_27535	COG2154	pterin-4-alpha-carbinolamine dehydratase
BKN51_27545	COG3654	unkown
BKN51_27565	COG2234	aminopeptidase activity
BKN51_27570	COG0012	GTP binding
BKN51_27585	COG0419	ATPase involved in DNA repair
BKN51_27590	COG0420	3'-5' exonuclease activity
BKN51_27615	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKN51_27625	COG1570	exodeoxyribonuclease VII activity
BKN51_27635	COG1722	exodeoxyribonuclease VII activity
BKN51_27650	COG0492	ferredoxin-NADP+ reductase activity
BKN51_27655	COG0114	fumarate hydratase activity
BKN51_27675	COG1793	dna ligase
BKN51_27705	COG1215	transferase activity, transferring glycosyl groups
BKN51_27710	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BKN51_27745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKN51_27760	COG1331	Highly conserved protein containing a thioredoxin domain
BKN51_27770	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKN51_27780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKN51_27790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKN51_27795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN51_27805	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BKN51_27870	COG0183	Belongs to the thiolase family
BKN51_27875	COG0477	Major facilitator Superfamily
BKN51_27880	COG2391	methyltransferase activity
BKN51_27925	COG1902	pentaerythritol trinitrate reductase activity
BKN51_27950	COG1472	Belongs to the glycosyl hydrolase 3 family
BKN51_27960	COG1309	transcriptional regulator
BKN51_27965	COG2124	cytochrome p450
BKN51_27970	COG0406	alpha-ribazole phosphatase activity
BKN51_27985	COG1960	acyl-CoA dehydrogenase activity
BKN51_28000	COG0745	RESPONSE REGULATOR receiver
BKN51_28020	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN51_28030	COG1960	acyl-CoA dehydrogenase activity
BKN51_28090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN51_28100	COG0583	DNA-binding transcription factor activity
BKN51_28115	COG1252	NADH dehydrogenase
BKN51_28125	COG1515	deoxyribonuclease V activity
BKN51_28140	COG1404	Belongs to the peptidase S8 family
BKN51_28145	COG4608	Belongs to the ABC transporter superfamily
BKN51_28150	COG0444	Belongs to the ABC transporter superfamily
BKN51_28160	COG0601	transmembrane transport
BKN51_28165	COG4166	transmembrane transport
BKN51_28190	COG0148	phosphopyruvate hydratase activity
BKN51_28205	COG1396	sequence-specific DNA binding
BKN51_28220	COG0672	)-iron permease
BKN51_28230	COG2837	iron assimilation
BKN51_28250	COG1131	(ABC) transporter
BKN51_28260	COG1595	DNA-templated transcription, initiation
BKN51_28265	COG1733	regulation of RNA biosynthetic process
BKN51_28300	COG2133	pyrroloquinoline quinone binding
BKN51_28340	COG3706	GGDEF domain
BKN51_28340	COG0745	RESPONSE REGULATOR receiver
BKN51_28345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKN51_28375	COG0193	aminoacyl-tRNA hydrolase activity
BKN51_28390	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_28395	COG0488	(ABC) transporter
BKN51_28400	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKN51_28405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKN51_28425	COG0084	hydrolase, TatD family'
BKN51_28430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN51_28535	COG2258	MOSC domain
BKN51_28550	COG4585	Histidine kinase
BKN51_28555	COG2197	response regulator
BKN51_28590	COG2226	methyltransferase
BKN51_28600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKN51_28610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN51_28630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKN51_28645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKN51_28655	COG1111	helicase
BKN51_28655	COG1205	dead DEAH box helicase
BKN51_28730	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKN51_28730	COG0315	cyclic pyranopterin monophosphate synthase activity
BKN51_28735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKN51_28745	COG5002	protein histidine kinase activity
BKN51_28750	COG0745	RESPONSE REGULATOR receiver
BKN51_28785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKN51_28795	COG1349	DNA-binding transcription factor activity
BKN51_28805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKN51_28815	COG2205	protein histidine kinase activity
BKN51_28825	COG2860	membrane
BKN51_28830	COG2197	response regulator
BKN51_28850	COG0596	Alpha beta hydrolase
BKN51_28860	COG1960	acyl-CoA dehydrogenase activity
BKN51_28865	COG1653	transport
BKN51_28880	COG0477	Major facilitator Superfamily
BKN51_28890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN51_28910	COG0277	FAD linked oxidase domain protein
BKN51_28920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BKN51_28955	COG1064	alcohol dehydrogenase
BKN51_28975	COG1960	acyl-CoA dehydrogenase activity
BKN51_28995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKN51_29015	COG3629	intracellular signal transduction
BKN51_29015	COG3903	Transcriptional regulator
BKN51_29050	COG4221	oxidoreductase activity
BKN51_29055	COG1309	transcriptional regulator
BKN51_29060	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BKN51_29070	COG4941	Belongs to the sigma-70 factor family
BKN51_29075	COG0789	Transcriptional regulator
BKN51_29090	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BKN51_29095	COG0583	DNA-binding transcription factor activity
BKN51_29105	COG2755	lipolytic protein G-D-S-L family
BKN51_29105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKN51_29150	COG1940	carbohydrate kinase activity
BKN51_29170	COG4336	lyase activity
BKN51_29175	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKN51_29180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKN51_29185	COG1984	allophanate hydrolase subunit 2
BKN51_29190	COG3145	DNA-N1-methyladenine dioxygenase activity
BKN51_29205	COG1321	iron dependent repressor
BKN51_29215	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BKN51_29220	COG1024	Enoyl-CoA hydratase
BKN51_29225	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_29240	COG1960	acyl-CoA dehydrogenase activity
BKN51_29245	COG1301	dicarboxylic acid transport
BKN51_29255	COG1169	isochorismate synthase
BKN51_29310	COG0277	FAD linked oxidase domain protein
BKN51_29345	COG4152	abc transporter atp-binding protein
BKN51_29350	COG1668	transmembrane transport
BKN51_29355	COG0415	Belongs to the DNA photolyase family
BKN51_29375	COG1960	acyl-CoA dehydrogenase activity
BKN51_29390	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKN51_29400	COG2017	converts alpha-aldose to the beta-anomer
BKN51_29405	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_29420	COG1309	transcriptional regulator
BKN51_29450	COG0259	pyridoxamine-phosphate oxidase activity
BKN51_29460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKN51_29465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKN51_29470	COG1116	anion transmembrane transporter activity
BKN51_29475	COG0642	Histidine kinase
BKN51_29505	COG0829	nickel cation binding
BKN51_29510	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BKN51_29520	COG0804	urea catabolic process
BKN51_29525	COG0832	Belongs to the urease beta subunit family
BKN51_29530	COG0831	urea catabolic process
BKN51_29555	COG1309	transcriptional regulator
BKN51_29570	COG1131	(ABC) transporter
BKN51_29585	COG2197	response regulator
BKN51_29590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKN51_29610	COG1136	(ABC) transporter
BKN51_29610	COG0577	efflux transmembrane transporter activity
BKN51_29615	COG0577	efflux transmembrane transporter activity
BKN51_29615	COG1136	(ABC) transporter
BKN51_29635	COG0745	RESPONSE REGULATOR receiver
BKN51_29640	COG2205	protein histidine kinase activity
BKN51_29660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKN51_29690	COG1120	ATPase activity
BKN51_29695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_29700	COG4558	Periplasmic binding protein
BKN51_29750	COG2814	Major facilitator Superfamily
BKN51_29760	COG2252	PERMEase
BKN51_29800	COG1278	Cold shock
BKN51_29820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKN51_29835	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_29840	COG0384	phenazine biosynthesis protein PhzF
BKN51_29845	COG3304	Inner membrane component domain
BKN51_29880	COG1846	Transcriptional regulator
BKN51_29885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKN51_29900	COG1388	LysM domain
BKN51_29910	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKN51_29945	COG2018	Roadblock/LC7 domain
BKN51_29960	COG2018	Roadblock/LC7 domain
BKN51_29970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKN51_29975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKN51_29980	COG1174	glycine betaine transport
BKN51_29985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKN51_29990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKN51_29990	COG1116	anion transmembrane transporter activity
BKN51_30000	COG3142	Participates in the control of copper homeostasis
BKN51_30020	COG1061	Type III restriction enzyme res subunit
BKN51_30035	COG3903	Transcriptional regulator
BKN51_30035	COG3629	intracellular signal transduction
BKN51_30040	COG4948	Mandelate Racemase Muconate Lactonizing
BKN51_30075	COG0459	protein refolding
BKN51_30085	COG1278	Cold shock
BKN51_30115	COG2261	transglycosylase associated protein
BKN51_30125	COG0688	phosphatidylethanolamine metabolic process
BKN51_30145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKN51_30170	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BKN51_30175	COG0351	phosphomethylpyrimidine kinase
BKN51_30185	COG1733	regulation of RNA biosynthetic process
BKN51_30215	COG2022	thiamine diphosphate biosynthetic process
BKN51_30230	COG0352	thiamine-phosphate diphosphorylase activity
BKN51_30240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKN51_30245	COG0477	Major facilitator Superfamily
BKN51_30250	COG2188	Transcriptional regulator
BKN51_30255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKN51_30260	COG2971	BadF BadG BcrA BcrD
BKN51_30300	COG3629	intracellular signal transduction
BKN51_30300	COG3903	Transcriptional regulator
BKN51_30305	COG5285	phytanoyl-CoA dioxygenase
BKN51_30310	COG1917	Cupin 2, conserved barrel domain protein
BKN51_30320	COG0456	acetyltransferase
BKN51_30325	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKN51_30355	COG5416	Lipopolysaccharide assembly protein A domain
BKN51_30365	COG0400	carboxylic ester hydrolase activity
BKN51_30370	COG0346	lactoylglutathione lyase activity
BKN51_30380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKN51_30425	COG1832	CoA-binding protein
BKN51_30435	COG1620	l-lactate permease
BKN51_30455	COG4941	Belongs to the sigma-70 factor family
BKN51_30460	COG3795	YCII-related domain
BKN51_30470	COG0583	DNA-binding transcription factor activity
BKN51_30475	COG1595	DNA-templated transcription, initiation
BKN51_30495	COG0640	Transcriptional regulator
BKN51_30575	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKN51_30605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BKN51_30610	COG2847	Copper chaperone PCu(A)C
BKN51_30615	COG1329	Transcriptional regulator
BKN51_30620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKN51_30625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKN51_30645	COG0215	cysteine-tRNA ligase activity
BKN51_30675	COG2267	carboxylic ester hydrolase activity
BKN51_30680	COG1309	transcriptional regulator
BKN51_30705	COG0235	Class ii aldolase
BKN51_30720	COG4399	Belongs to the UPF0754 family
BKN51_30725	COG4399	Belongs to the UPF0754 family
BKN51_30740	COG1120	ATPase activity
BKN51_30745	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKN51_30750	COG1609	Transcriptional regulator
BKN51_30760	COG1194	a g-specific adenine glycosylase
BKN51_30770	COG2814	Major facilitator Superfamily
BKN51_30805	COG3118	belongs to the thioredoxin family
BKN51_30810	COG0596	Alpha beta hydrolase
BKN51_30830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKN51_30865	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BKN51_30875	COG0443	Heat shock 70 kDa protein
BKN51_30880	COG0542	response to heat
BKN51_30915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKN51_30920	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BKN51_30925	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKN51_30950	COG0789	Transcriptional regulator
BKN51_30965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKN51_30975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKN51_31005	COG0037	tRNA processing
BKN51_31020	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BKN51_31025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKN51_31035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKN51_31050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKN51_31055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKN51_31075	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_31080	COG0657	acetylesterase activity
BKN51_31100	COG0470	DNA polymerase III
BKN51_31105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKN51_31135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKN51_31135	COG1754	DNA topoisomerase type I activity
BKN51_31160	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BKN51_31165	COG1205	dead DEAH box helicase
BKN51_31165	COG1111	helicase
BKN51_31215	COG1472	Belongs to the glycosyl hydrolase 3 family
BKN51_31220	COG3876	Protein conserved in bacteria
BKN51_31225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKN51_31230	COG1737	Transcriptional regulator
BKN51_31235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKN51_31240	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BKN51_31250	COG0640	Transcriptional regulator
BKN51_31280	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_31290	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BKN51_31300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKN51_31305	COG3708	Transcriptional regulator
BKN51_31305	COG2207	Transcriptional regulator
BKN51_31345	COG3104	oligopeptide transport
BKN51_31350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKN51_31360	COG0596	Alpha beta hydrolase
BKN51_31380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN51_31385	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKN51_31415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN51_31465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKN51_31470	COG1408	metallophosphoesterase
BKN51_31500	COG0076	glutamate decarboxylase activity
BKN51_31505	COG0783	Belongs to the Dps family
BKN51_31510	COG1764	response to oxidative stress
BKN51_31545	COG1690	Belongs to the RtcB family
BKN51_31630	COG0583	DNA-binding transcription factor activity
BKN51_31635	COG0697	spore germination
BKN51_31650	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_31665	COG4608	Belongs to the ABC transporter superfamily
BKN51_31670	COG0444	Belongs to the ABC transporter superfamily
BKN51_31685	COG0747	negative chemotaxis
BKN51_31700	COG0463	Glycosyl transferase, family 2
BKN51_31715	COG1215	transferase activity, transferring glycosyl groups
BKN51_31720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKN51_31725	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKN51_31730	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKN51_31735	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKN51_31755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKN51_31760	COG2205	protein histidine kinase activity
BKN51_31765	COG0745	RESPONSE REGULATOR receiver
BKN51_31785	COG2197	response regulator
BKN51_31815	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN51_31820	COG5479	isomerase activity
BKN51_31820	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BKN51_31825	COG5479	isomerase activity
BKN51_31825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BKN51_31885	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
BKN51_31920	COG1473	amidohydrolase
BKN51_31925	COG4702	Belongs to the UPF0303 family
BKN51_31955	COG3973	AAA domain
BKN51_32015	COG0596	Alpha beta hydrolase
BKN51_32020	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BKN51_32025	COG0745	RESPONSE REGULATOR receiver
BKN51_32025	COG3706	GGDEF domain
BKN51_32030	COG1316	TRANSCRIPTIONal
BKN51_32035	COG0704	Plays a role in the regulation of phosphate uptake
BKN51_32040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKN51_32045	COG0581	inorganic phosphate transmembrane transporter activity
BKN51_32055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKN51_32065	COG0745	RESPONSE REGULATOR receiver
BKN51_32095	COG4044	May play a role in the intracellular transport of hydrophobic ligands
BKN51_32105	COG1984	allophanate hydrolase subunit 2
BKN51_32120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKN51_32155	COG1569	PIN domain
BKN51_32160	COG3311	Transcriptional regulator
BKN51_32185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKN51_32255	COG1132	(ABC) transporter
BKN51_32260	COG1132	(ABC) transporter
BKN51_32265	COG0047	phosphoribosylformylglycinamidine synthase activity
BKN51_32270	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKN51_32300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKN51_32305	COG2311	Membrane
BKN51_32320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKN51_32330	COG1126	abc transporter atp-binding protein
BKN51_32335	COG0765	amino acid transport
BKN51_32340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN51_32345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN51_32355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKN51_32395	COG0436	Aminotransferase
BKN51_32410	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_32415	COG3953	SLT domain
BKN51_32415	COG5412	phage tail tape measure protein
BKN51_32450	COG0584	glycerophosphoryl diester phosphodiesterase
BKN51_32460	COG2814	Major facilitator Superfamily
BKN51_32475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKN51_32495	COG0601	transmembrane transport
BKN51_32500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKN51_32505	COG4172	Belongs to the ABC transporter superfamily
BKN51_32510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_32520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_32570	COG0667	Aldo Keto reductase
BKN51_32575	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_32620	COG0586	Pfam SNARE associated Golgi protein
BKN51_32625	COG0277	FAD linked oxidase domain protein
BKN51_32630	COG0477	Major facilitator Superfamily
BKN51_32640	COG3467	pyridoxamine 5'-phosphate
BKN51_32650	COG0477	Major facilitator Superfamily
BKN51_32655	COG0586	Pfam SNARE associated Golgi protein
BKN51_32665	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_32670	COG1072	(Pantothenic acid kinase))
BKN51_32675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKN51_32695	COG1609	Transcriptional regulator
BKN51_32700	COG1609	Transcriptional regulator
BKN51_32715	COG0243	molybdopterin cofactor binding
BKN51_32720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKN51_32740	COG0577	efflux transmembrane transporter activity
BKN51_32740	COG1136	(ABC) transporter
BKN51_32770	COG0542	response to heat
BKN51_32840	COG3629	intracellular signal transduction
BKN51_32840	COG3903	Transcriptional regulator
BKN51_32845	COG0789	Transcriptional regulator
BKN51_32850	COG0484	heat shock protein binding
BKN51_32855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKN51_32860	COG0443	Heat shock 70 kDa protein
BKN51_32890	COG3226	Transcriptional regulator
BKN51_32895	COG2076	Multidrug Resistance protein
BKN51_32900	COG2181	nitrate reductase activity
BKN51_32900	COG0247	lactate metabolic process
BKN51_32915	COG2340	Cysteine-rich secretory protein family
BKN51_32920	COG1846	Transcriptional regulator
BKN51_32925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_32930	COG0717	Belongs to the dCTP deaminase family
BKN51_32985	COG2188	Transcriptional regulator
BKN51_32990	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BKN51_33030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN51_33040	COG0737	Belongs to the 5'-nucleotidase family
BKN51_33045	COG2267	carboxylic ester hydrolase activity
BKN51_33065	COG3663	DNA glycosylase
BKN51_33070	COG2197	response regulator
BKN51_33075	COG1960	acyl-CoA dehydrogenase activity
BKN51_33100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKN51_33160	COG1126	abc transporter atp-binding protein
BKN51_33165	COG0765	amino acid transport
BKN51_33170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN51_33185	COG1305	Transglutaminase-like
BKN51_33190	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_33195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_33205	COG0596	Alpha beta hydrolase
BKN51_33210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN51_33220	COG0022	dehydrogenase e1 component
BKN51_33225	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKN51_33240	COG3030	protein affecting phage T7 exclusion by the F plasmid
BKN51_33255	COG1309	transcriptional regulator
BKN51_33260	COG2030	dehydratase
BKN51_33265	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_33270	COG0183	Belongs to the thiolase family
BKN51_33295	COG0584	glycerophosphoryl diester phosphodiesterase
BKN51_33300	COG0789	Transcriptional regulator
BKN51_33310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKN51_33315	COG0456	acetyltransferase
BKN51_33315	COG0454	-acetyltransferase
BKN51_33365	COG4133	protoheme IX ABC transporter activity
BKN51_33375	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BKN51_33410	COG4585	Histidine kinase
BKN51_33415	COG2197	response regulator
BKN51_33460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKN51_33470	COG1136	(ABC) transporter
BKN51_33480	COG2197	response regulator
BKN51_33485	COG0402	S-adenosylhomocysteine deaminase activity
BKN51_33490	COG4221	oxidoreductase activity
BKN51_33495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN51_33500	COG2226	methyltransferase
BKN51_33520	COG2814	Major facilitator Superfamily
BKN51_33530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKN51_33540	COG1695	Transcriptional regulator
BKN51_33550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKN51_33555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKN51_33560	COG0673	inositol 2-dehydrogenase activity
BKN51_33565	COG1940	carbohydrate kinase activity
BKN51_33610	COG0360	Binds together with S18 to 16S ribosomal RNA
BKN51_33620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKN51_33625	COG0359	binds to the 23S rRNA
BKN51_33655	COG0667	Aldo Keto reductase
BKN51_33665	COG1309	transcriptional regulator
BKN51_33705	COG3384	dioxygenase
BKN51_33710	COG0738	Major facilitator superfamily
BKN51_33715	COG1940	carbohydrate kinase activity
BKN51_33715	COG1846	Transcriptional regulator
BKN51_33740	COG2197	response regulator
BKN51_33765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKN51_33770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKN51_33805	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_33810	COG0495	leucyl-tRNA aminoacylation
BKN51_33880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_33890	COG4585	Histidine kinase
BKN51_33900	COG0617	tRNA 3'-terminal CCA addition
BKN51_33930	COG1595	DNA-templated transcription, initiation
BKN51_33945	COG0492	ferredoxin-NADP+ reductase activity
BKN51_33945	COG3118	belongs to the thioredoxin family
BKN51_33950	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKN51_33950	COG3409	Peptidoglycan-binding domain 1 protein
BKN51_33965	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKN51_33980	COG1192	Involved in chromosome partitioning
BKN51_33985	COG0357	Ribosomal RNA small subunit methyltransferase G
BKN51_33995	COG0706	membrane insertase activity
BKN51_34015	COG0592	DNA-directed DNA polymerase activity
BKN51_34020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BKN51_34025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKN51_34035	COG0187	DNA topoisomerase II activity
BKN51_34040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKN51_34090	COG0789	Transcriptional regulator
BKN51_34100	COG2197	response regulator
BKN51_34105	COG2203	Gaf domain
BKN51_34105	COG4585	Histidine kinase
BKN51_34160	COG0705	Rhomboid family
BKN51_34160	COG0457	Tetratricopeptide repeat
BKN51_34180	COG3764	Sortase (surface protein transpeptidase)
BKN51_34200	COG1131	(ABC) transporter
BKN51_34250	COG0515	serine threonine protein kinase
BKN51_34255	COG0768	penicillin binding
BKN51_34270	COG1716	ATPase activity
BKN51_34275	COG1716	ATPase activity
BKN51_34295	COG0626	cystathionine gamma-synthase activity
BKN51_34320	COG2186	Transcriptional regulator
BKN51_34325	COG0747	negative chemotaxis
BKN51_34340	COG0444	Belongs to the ABC transporter superfamily
BKN51_34345	COG4608	Belongs to the ABC transporter superfamily
BKN51_34350	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_34360	COG0154	amidase activity
BKN51_34375	COG2301	Belongs to the HpcH HpaI aldolase family
BKN51_34395	COG0702	epimerase
BKN51_34400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKN51_34470	COG2372	response to copper ion
BKN51_34470	COG1276	copper resistance
BKN51_34485	COG1174	glycine betaine transport
BKN51_34495	COG1174	glycine betaine transport
BKN51_34520	COG2226	methyltransferase
BKN51_34530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKN51_34550	COG0405	Gamma-glutamyltransferase
BKN51_34565	COG0477	Major facilitator Superfamily
BKN51_34580	COG4585	Histidine kinase
BKN51_34585	COG2197	response regulator
BKN51_34605	COG0438	transferase activity, transferring glycosyl groups
BKN51_34610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKN51_34675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKN51_34685	COG3275	phosphorelay sensor kinase activity
BKN51_34700	COG3279	Response regulator of the LytR AlgR family
BKN51_34710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN51_34720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN51_34765	COG1191	sigma factor activity
BKN51_34780	COG2235	arginine
BKN51_34845	COG1271	oxidase subunit
BKN51_34850	COG1294	oxidase, subunit
BKN51_34855	COG4988	ABC transporter
BKN51_34920	COG4715	Zinc finger, swim domain protein
BKN51_34940	COG1072	(Pantothenic acid kinase))
BKN51_34955	COG0406	alpha-ribazole phosphatase activity
BKN51_34990	COG0754	glutathionylspermidine amidase activity
BKN51_34995	COG3766	membrane
BKN51_35000	COG0596	Alpha beta hydrolase
BKN51_35005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKN51_35010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKN51_35020	COG0579	oxidoreductase
BKN51_35025	COG1309	transcriptional regulator
BKN51_35035	COG0477	Major facilitator Superfamily
BKN51_35060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKN51_35070	COG0438	transferase activity, transferring glycosyl groups
BKN51_35075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKN51_35140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKN51_35155	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_35205	COG0561	phosphatase activity
BKN51_35210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_35225	COG0671	phosphoesterase, PA-phosphatase related
BKN51_35230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BKN51_35270	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_35275	COG0277	FAD linked oxidase domain protein
BKN51_35285	COG1216	Glycosyl transferase, family 2
BKN51_35320	COG1216	Glycosyl transferase, family 2
BKN51_35340	COG3209	COG3209 Rhs family protein
BKN51_35350	COG0596	Alpha beta hydrolase
BKN51_35365	COG0604	alcohol dehydrogenase
BKN51_35370	COG2234	aminopeptidase activity
BKN51_35385	COG4941	Belongs to the sigma-70 factor family
BKN51_35390	COG3795	YCII-related domain
BKN51_35450	COG3209	COG3209 Rhs family protein
BKN51_35480	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKN51_35480	COG1672	PFAM Archaeal ATPase
BKN51_35495	COG1522	sequence-specific DNA binding
BKN51_35515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKN51_35520	COG2186	Transcriptional regulator
BKN51_35535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKN51_35560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKN51_35610	COG1074	ATP-dependent DNA helicase activity
BKN51_35630	COG1309	transcriptional regulator
BKN51_35635	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_35715	COG3559	Exporter of polyketide antibiotics
BKN51_35720	COG1131	(ABC) transporter
BKN51_35760	COG1660	Displays ATPase and GTPase activities
BKN51_35785	COG2175	clavaminate synthase activity
BKN51_35795	COG0287	Prephenate dehydrogenase
BKN51_35800	COG1902	pentaerythritol trinitrate reductase activity
BKN51_35800	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKN51_35815	COG1846	Transcriptional regulator
BKN51_35850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKN51_35855	COG2318	DinB family
BKN51_35955	COG1278	Cold shock
BKN51_35965	COG2197	response regulator
BKN51_35970	COG4585	Histidine kinase
BKN51_36005	COG0515	serine threonine protein kinase
BKN51_36010	COG1132	(ABC) transporter
BKN51_36015	COG1132	(ABC) transporter
BKN51_36030	COG0028	Belongs to the TPP enzyme family
BKN51_36040	COG2197	response regulator
BKN51_36045	COG4585	Histidine kinase
BKN51_36065	COG2197	response regulator
BKN51_36075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN51_36100	COG0515	serine threonine protein kinase
BKN51_36120	COG1595	DNA-templated transcription, initiation
BKN51_36135	COG1278	Cold shock
BKN51_36170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKN51_36175	COG1136	(ABC) transporter
BKN51_36180	COG0577	efflux transmembrane transporter activity
BKN51_36180	COG1136	(ABC) transporter
BKN51_36210	COG2233	PERMEase
BKN51_36225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKN51_36290	COG3226	Transcriptional regulator
BKN51_36325	COG2364	Membrane
BKN51_36330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_36350	COG2733	membrane
BKN51_36370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKN51_36370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKN51_36375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKN51_36400	COG2986	histidine ammonia-lyase
BKN51_36415	COG1174	glycine betaine transport
BKN51_36430	COG2130	NADP-dependent
BKN51_36460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKN51_36475	COG0438	transferase activity, transferring glycosyl groups
BKN51_36490	COG0588	phosphoglycerate mutase activity
BKN51_36505	COG5002	protein histidine kinase activity
BKN51_36535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKN51_36555	COG0560	Phosphoserine phosphatase
BKN51_36565	COG1595	DNA-templated transcription, initiation
BKN51_36570	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_36585	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BKN51_36590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKN51_36595	COG0181	hydroxymethylbilane synthase activity
BKN51_36600	COG1648	precorrin-2 dehydrogenase activity
BKN51_36600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKN51_36610	COG1914	H( )-stimulated, divalent metal cation uptake system
BKN51_36640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKN51_36645	COG0406	alpha-ribazole phosphatase activity
BKN51_36660	COG0785	Cytochrome C biogenesis protein
BKN51_36670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKN51_36690	COG1522	sequence-specific DNA binding
BKN51_36700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN51_36715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BKN51_36720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BKN51_36755	COG0438	transferase activity, transferring glycosyl groups
BKN51_36780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKN51_36785	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKN51_36790	COG0649	NAD binding
BKN51_36805	COG1034	ATP synthesis coupled electron transport
BKN51_36810	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BKN51_36815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKN51_36820	COG0839	Belongs to the complex I subunit 6 family
BKN51_36825	COG0713	ATP synthesis coupled electron transport
BKN51_36830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKN51_36840	COG1007	ATP synthesis coupled electron transport
BKN51_36890	COG1196	nuclear chromosome segregation
BKN51_36930	COG1013	pyruvate-flavodoxin oxidoreductase activity
BKN51_36935	COG0674	pyruvate-flavodoxin oxidoreductase activity
BKN51_36935	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BKN51_36945	COG1522	sequence-specific DNA binding
BKN51_36950	COG1834	amidinotransferase
BKN51_36975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKN51_36995	COG0367	asparagine synthase
BKN51_37045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKN51_37060	COG0463	Glycosyl transferase, family 2
BKN51_37070	COG4310	Domain of unknown function (DUF2172)
BKN51_37085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKN51_37115	COG0501	Belongs to the peptidase M48B family
BKN51_37145	COG1666	GTP binding
BKN51_37165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKN51_37190	COG0346	lactoylglutathione lyase activity
BKN51_37195	COG0640	Transcriptional regulator
BKN51_37200	COG2197	response regulator
BKN51_37205	COG4585	Histidine kinase
BKN51_37210	COG0586	Pfam SNARE associated Golgi protein
BKN51_37220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKN51_37250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKN51_37255	COG2030	dehydratase
BKN51_37265	COG2755	lipolytic protein G-D-S-L family
BKN51_37275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN51_37280	COG0436	Aminotransferase
BKN51_37300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKN51_37305	COG0081	regulation of translation
BKN51_37310	COG2267	carboxylic ester hydrolase activity
BKN51_37320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKN51_37325	COG0222	ribosome binding
BKN51_37340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKN51_37365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKN51_37390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKN51_37395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKN51_37400	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BKN51_37455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKN51_37460	COG0049	tRNA binding
BKN51_37465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKN51_37475	COG0051	transcription antitermination factor activity, RNA binding
BKN51_37480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKN51_37485	COG0088	Forms part of the polypeptide exit tunnel
BKN51_37490	COG0089	rRNA binding
BKN51_37495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKN51_37500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKN51_37505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKN51_37510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKN51_37515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKN51_37520	COG0255	Belongs to the universal ribosomal protein uL29 family
BKN51_37525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKN51_37530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKN51_37535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKN51_37540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKN51_37550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKN51_37555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKN51_37560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKN51_37565	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKN51_37570	COG1841	ribosomal large subunit assembly
BKN51_37585	COG1280	lysine exporter protein (LysE YggA)
BKN51_37595	COG0563	adenylate kinase activity
BKN51_37610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKN51_37615	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKN51_37625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKN51_37630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKN51_37635	COG0202	RNA polymerase activity
BKN51_37640	COG0203	ribosomal protein L17
BKN51_37645	COG0101	tRNA pseudouridine synthase activity
BKN51_37680	COG1404	Belongs to the peptidase S8 family
BKN51_37690	COG1674	ftsk spoiiie
BKN51_37695	COG0443	Heat shock 70 kDa protein
BKN51_37725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKN51_37735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKN51_37760	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_37765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKN51_37800	COG1349	DNA-binding transcription factor activity
BKN51_37805	COG1070	Carbohydrate kinase
BKN51_37810	COG3842	ATPase activity
BKN51_37815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKN51_37825	COG0802	atpase or kinase
BKN51_37835	COG0825	malonyl-CoA metabolic process
BKN51_37835	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKN51_37840	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_37850	COG0456	acetyltransferase
BKN51_37855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKN51_37860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKN51_37880	COG1215	transferase activity, transferring glycosyl groups
BKN51_37890	COG0546	phosphoglycolate phosphatase activity
BKN51_37895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKN51_37900	COG0459	protein refolding
BKN51_37950	COG0516	GMP reductase activity
BKN51_37955	COG2318	DinB family
BKN51_37970	COG0277	FAD linked oxidase domain protein
BKN51_37975	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_37990	COG0519	Catalyzes the synthesis of GMP from XMP
BKN51_37990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKN51_38030	COG0583	DNA-binding transcription factor activity
BKN51_38080	COG0739	heme binding
BKN51_38095	COG0045	succinate-CoA ligase (ADP-forming) activity
BKN51_38120	COG0138	bifunctional purine biosynthesis protein purh
BKN51_38165	COG0587	DNA-directed DNA polymerase activity
BKN51_38200	COG2814	Major facilitator Superfamily
BKN51_38205	COG0640	Transcriptional regulator
BKN51_38210	COG2814	Major facilitator Superfamily
BKN51_38245	COG0583	DNA-binding transcription factor activity
BKN51_38255	COG0667	Aldo Keto reductase
BKN51_38265	COG1522	sequence-specific DNA binding
BKN51_38275	COG2264	protein methyltransferase activity
BKN51_38300	COG1234	tRNA 3'-trailer cleavage
BKN51_38355	COG0180	Tryptophanyl-tRNA synthetase
BKN51_38360	COG1295	ribonuclease BN
BKN51_38370	COG1686	Belongs to the peptidase S11 family
BKN51_38395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKN51_38400	COG1053	succinate dehydrogenase
BKN51_38410	COG2009	succinate dehydrogenase
BKN51_38450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKN51_38455	COG2271	Major facilitator Superfamily
BKN51_38480	COG1733	regulation of RNA biosynthetic process
BKN51_38490	COG1063	alcohol dehydrogenase
BKN51_38505	COG0395	ABC-type sugar transport system, permease component
BKN51_38525	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_38530	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_38535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKN51_38540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKN51_38580	COG0667	Aldo Keto reductase
BKN51_38585	COG0667	Aldo Keto reductase
BKN51_38625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKN51_38680	COG1473	amidohydrolase
BKN51_38680	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKN51_38720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKN51_38725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKN51_38730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKN51_38755	COG4770	biotin carboxylase activity
BKN51_38770	COG1301	dicarboxylic acid transport
BKN51_38775	COG0424	maF-like protein
BKN51_38780	COG1472	Belongs to the glycosyl hydrolase 3 family
BKN51_38820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKN51_38830	COG4585	Histidine kinase
BKN51_38840	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKN51_38860	COG0640	Transcriptional regulator
BKN51_38870	COG4946	Tricorn protease homolog
BKN51_38870	COG0823	Involved in the tonB-independent uptake of proteins
BKN51_38870	COG1506	peptidase
BKN51_38915	COG3103	Sh3 type 3 domain protein
BKN51_38915	COG0791	NLP P60 protein
BKN51_38915	COG1388	LysM domain
BKN51_38920	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BKN51_38920	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BKN51_38945	COG0483	inositol monophosphate 1-phosphatase activity
BKN51_38955	COG3850	Histidine kinase
BKN51_38955	COG5002	protein histidine kinase activity
BKN51_38970	COG2197	response regulator
BKN51_38985	COG0477	Major facilitator Superfamily
BKN51_39015	COG5650	phosphatidylinositol metabolic process
BKN51_39025	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKN51_39030	COG0318	PFAM AMP-dependent synthetase and ligase
BKN51_39050	COG2259	Doxx family
BKN51_39060	COG1316	TRANSCRIPTIONal
BKN51_39065	COG1316	TRANSCRIPTIONal
BKN51_39095	COG0438	transferase activity, transferring glycosyl groups
BKN51_39135	COG1725	Transcriptional regulator
BKN51_39150	COG0778	Nitroreductase
BKN51_39150	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BKN51_39185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN51_39195	COG2171	N-acyltransferase activity
BKN51_39205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN51_39250	COG3291	Pkd domain containing protein
BKN51_39255	COG1611	Belongs to the LOG family
BKN51_39270	COG0463	Glycosyl transferase, family 2
BKN51_39280	COG4988	ABC transporter
BKN51_39285	COG1294	oxidase, subunit
BKN51_39290	COG1271	oxidase subunit
BKN51_39325	COG2818	Glycosylase
BKN51_39335	COG1024	Enoyl-CoA hydratase
BKN51_39345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKN51_39350	COG0671	phosphoesterase, PA-phosphatase related
BKN51_39355	COG0583	DNA-binding transcription factor activity
BKN51_39360	COG2814	Major facilitator Superfamily
BKN51_39375	COG5662	AntiSigma factor
BKN51_39385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKN51_39390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKN51_39405	COG2239	Acts as a magnesium transporter
BKN51_39415	COG0330	HflC and HflK could
BKN51_39445	COG3629	intracellular signal transduction
BKN51_39445	COG3903	Transcriptional regulator
BKN51_39485	COG1309	transcriptional regulator
BKN51_39505	COG0598	Magnesium transport protein CorA
BKN51_39530	COG0613	PHP domain protein
BKN51_39535	COG2095	MarC family integral membrane protein
BKN51_39560	COG0513	Belongs to the DEAD box helicase family
BKN51_39595	COG2267	carboxylic ester hydrolase activity
BKN51_39610	COG0596	Alpha beta hydrolase
BKN51_39635	COG1136	(ABC) transporter
BKN51_39645	COG0243	molybdopterin cofactor binding
BKN51_39650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKN51_39655	COG2223	nitrite transmembrane transporter activity
BKN51_39660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKN51_39660	COG2146	nitrite reductase [NAD(P)H] activity
BKN51_39665	COG2146	nitrite reductase [NAD(P)H] activity
BKN51_39665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKN51_39670	COG0745	RESPONSE REGULATOR receiver
BKN51_39685	COG2378	regulation of single-species biofilm formation
BKN51_39695	COG4585	Histidine kinase
BKN51_39755	COG0714	Associated with various cellular activities
BKN51_39760	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BKN51_39810	COG0612	Peptidase, M16
BKN51_39830	COG1175	transmembrane transport
BKN51_39835	COG0395	ABC-type sugar transport system, permease component
BKN51_39840	COG1486	melibiose metabolic process
BKN51_39855	COG0640	Transcriptional regulator
BKN51_39865	COG3265	gluconokinase activity
BKN51_39875	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BKN51_39905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKN51_39915	COG0406	alpha-ribazole phosphatase activity
BKN51_39915	COG0328	RNA-DNA hybrid ribonuclease activity
BKN51_39930	COG2197	response regulator
BKN51_40020	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BKN51_40025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN51_40030	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_40055	COG1012	belongs to the aldehyde dehydrogenase family
BKN51_40060	COG3842	ATPase activity
BKN51_40065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKN51_40070	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKN51_40075	COG1177	transmembrane transport
BKN51_40085	COG0596	Alpha beta hydrolase
BKN51_40095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKN51_40100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BKN51_40100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKN51_40105	COG2318	DinB family
BKN51_40120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKN51_40120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKN51_40125	COG0653	protein targeting
BKN51_40150	COG0174	glutamine synthetase
BKN51_40155	COG0154	amidase activity
BKN51_40175	COG1522	sequence-specific DNA binding
BKN51_40185	COG0505	Belongs to the CarA family
BKN51_40195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BKN51_40205	COG0174	glutamine synthetase
BKN51_40255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKN51_40275	COG3480	Lon protease (S16) C-terminal proteolytic domain
BKN51_40285	COG1615	UPF0182 protein
BKN51_40315	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKN51_40320	COG2884	Cell division ATP-binding protein ftsE
BKN51_40325	COG2177	Part of the ABC transporter FtsEX involved in
BKN51_40330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKN51_40350	COG2197	response regulator
BKN51_40355	COG4585	Histidine kinase
BKN51_40375	COG0596	Alpha beta hydrolase
BKN51_40385	COG2986	histidine ammonia-lyase
BKN51_40390	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BKN51_40400	COG0402	S-adenosylhomocysteine deaminase activity
BKN51_40405	COG1228	amidohydrolase
BKN51_40420	COG4585	Histidine kinase
BKN51_40425	COG2197	response regulator
BKN51_40460	COG1643	Atp-dependent helicase
BKN51_40465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN51_40480	COG0583	DNA-binding transcription factor activity
BKN51_40505	COG0183	Belongs to the thiolase family
BKN51_40515	COG2030	dehydratase
BKN51_40520	COG1028	Short-chain dehydrogenase reductase Sdr
BKN51_40525	COG1960	acyl-CoA dehydrogenase activity
BKN51_40530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKN51_40550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKN51_40555	COG0187	DNA topoisomerase II activity
BKN51_40590	COG0667	Aldo Keto reductase
BKN51_40630	COG3285	dna ligase
BKN51_40630	COG1793	dna ligase
BKN51_40655	COG5001	Diguanylate cyclase
BKN51_40690	COG0438	transferase activity, transferring glycosyl groups
BKN51_40705	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKN51_40715	COG0483	inositol monophosphate 1-phosphatase activity
BKN51_40720	COG0438	transferase activity, transferring glycosyl groups
BKN51_40730	COG2084	Dehydrogenase
BKN51_40740	COG1472	Belongs to the glycosyl hydrolase 3 family
BKN51_40745	COG0395	ABC-type sugar transport system, permease component
BKN51_40775	COG1309	transcriptional regulator
BKN51_40805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN51_40810	COG0667	Aldo Keto reductase
BKN51_40815	COG0596	Alpha beta hydrolase
BKN51_40840	COG0326	Molecular chaperone. Has ATPase activity
BKN51_40855	COG1120	ATPase activity
BKN51_40865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKN51_40870	COG1121	(ABC) transporter
BKN51_40875	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKN51_40880	COG0247	lactate metabolic process
BKN51_40880	COG2181	nitrate reductase activity
BKN51_40900	COG2255	four-way junction helicase activity
BKN51_40975	COG3290	protein histidine kinase activity
BKN51_40980	COG4565	transcriptional regulatory protein
BKN51_40985	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKN51_40995	COG0477	Major facilitator Superfamily
BKN51_41000	COG1940	carbohydrate kinase activity
BKN51_41010	COG1129	ABC transporter
BKN51_41015	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKN51_41025	COG0673	inositol 2-dehydrogenase activity
BKN51_41090	COG1595	DNA-templated transcription, initiation
BKN51_41100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKN51_41105	COG4977	sequence-specific DNA binding
BKN51_41135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKN51_41155	COG5650	phosphatidylinositol metabolic process
BKN51_41160	COG2207	Transcriptional regulator
BKN51_41185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKN51_41195	COG1846	Transcriptional regulator
BKN51_41200	COG2814	Major facilitator Superfamily
BKN51_41205	COG4552	Acetyltransferase involved in intracellular survival and related
BKN51_41250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKN51_41260	COG3511	phospholipase C
BKN51_41280	COG0697	spore germination
BKN51_41395	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKN51_41400	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BKN51_41415	COG1132	(ABC) transporter
BKN51_41440	COG2124	cytochrome p450
BKN51_41445	COG2124	cytochrome p450
BKN51_41450	COG2124	cytochrome p450
BKN51_41455	COG2124	cytochrome p450
BKN51_41465	COG1819	glycosyl
BKN51_41480	COG1819	glycosyl
BKN51_41490	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN51_41560	COG1024	Enoyl-CoA hydratase
BKN51_41565	COG1024	Enoyl-CoA hydratase
BKN51_41570	COG1024	Enoyl-CoA hydratase
BKN51_41575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKN51_41580	COG1733	regulation of RNA biosynthetic process
BKN51_41595	COG0667	Aldo Keto reductase
BKN51_41610	COG1733	regulation of RNA biosynthetic process
BKN51_41635	COG4249	Peptidase C14 caspase catalytic subunit p20
BKN51_41635	COG2319	Wd-40 repeat
BKN51_41645	COG0402	S-adenosylhomocysteine deaminase activity
BKN51_41725	COG1733	regulation of RNA biosynthetic process
BKN51_41745	COG0596	Alpha beta hydrolase
BKN51_41750	COG2207	Transcriptional regulator
BKN51_41755	COG0667	Aldo Keto reductase
BKN51_41760	COG0154	amidase activity
BKN51_41830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BKN51_41835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_41840	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN51_41850	COG1132	(ABC) transporter
BKN51_41875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKN51_42035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN51_42040	COG0765	amino acid transport
BKN51_42060	COG0596	Alpha beta hydrolase
BKN51_42065	COG1131	(ABC) transporter
BKN51_42090	COG2186	Transcriptional regulator
BKN51_42095	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKN51_42100	COG1129	ABC transporter
BKN51_42120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKN51_42145	COG2826	transposase and inactivated derivatives, IS30 family
BKN51_42160	COG4991	sh3 domain protein
BKN51_42165	COG3903	Transcriptional regulator
BKN51_42165	COG3629	intracellular signal transduction
BKN51_42170	COG4991	sh3 domain protein
BKN51_42175	COG3540	Alkaline phosphatase
BKN51_42185	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BKN51_42190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKN51_42195	COG4585	Histidine kinase
BKN51_42205	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BKN51_42210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKN51_42215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN51_42225	COG0513	Belongs to the DEAD box helicase family