locus-tag	class	description
L3Q65_00040	COG1192	Involved in chromosome partitioning
L3Q65_00255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L3Q65_00440	COG4974	Belongs to the 'phage' integrase family
L3Q65_00590	COG1475	DNA binding
L3Q65_00595	COG1192	Involved in chromosome partitioning
L3Q65_00610	COG0494	nUDIX hydrolase
L3Q65_00935	COG0494	nUDIX hydrolase
L3Q65_01005	COG3629	intracellular signal transduction
L3Q65_01005	COG3903	Transcriptional regulator
L3Q65_01170	COG1834	amidinotransferase
L3Q65_01210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L3Q65_01225	COG1845	cytochrome c oxidase, subunit III
L3Q65_01230	COG2010	Cytochrome c
L3Q65_01240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L3Q65_01280	COG0438	transferase activity, transferring glycosyl groups
L3Q65_01295	COG2124	cytochrome p450
L3Q65_01300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L3Q65_01305	COG0659	secondary active sulfate transmembrane transporter activity
L3Q65_01310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
L3Q65_01320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
L3Q65_01330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L3Q65_01335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L3Q65_01345	COG1404	Belongs to the peptidase S8 family
L3Q65_01385	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_01425	COG1674	ftsk spoiiie
L3Q65_01450	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
L3Q65_01465	COG0477	Major facilitator Superfamily
L3Q65_01470	COG4977	sequence-specific DNA binding
L3Q65_01505	COG2197	response regulator
L3Q65_01520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L3Q65_01525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
L3Q65_01530	COG0131	Imidazoleglycerol-phosphate dehydratase
L3Q65_01540	COG1234	tRNA 3'-trailer cleavage
L3Q65_01555	COG2409	Drug exporters of the RND superfamily
L3Q65_01560	COG1309	transcriptional regulator
L3Q65_01565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L3Q65_01575	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
L3Q65_01585	COG3959	Transketolase, thiamine diphosphate binding domain
L3Q65_01590	COG3958	Transketolase
L3Q65_01600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L3Q65_01605	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
L3Q65_01650	COG0107	imidazoleglycerol-phosphate synthase activity
L3Q65_01670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L3Q65_01680	COG0134	indole-3-glycerol-phosphate synthase activity
L3Q65_01685	COG0133	tryptophan synthase activity
L3Q65_01690	COG0159	tryptophan synthase activity
L3Q65_01705	COG0174	glutamine synthetase
L3Q65_01720	COG1473	amidohydrolase
L3Q65_01725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
L3Q65_01745	COG0070	glutamate synthase
L3Q65_01745	COG0069	glutamate synthase activity
L3Q65_01745	COG0067	glutamate synthase
L3Q65_01770	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
L3Q65_01785	COG2268	Band 7 protein
L3Q65_01795	COG0515	serine threonine protein kinase
L3Q65_01795	COG2815	serine threonine protein kinase
L3Q65_01840	COG0142	geranyltranstransferase activity
L3Q65_01910	COG0242	peptide deformylase activity
L3Q65_01915	COG1201	RNA secondary structure unwinding
L3Q65_01925	COG0443	Heat shock 70 kDa protein
L3Q65_01935	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
L3Q65_01940	COG2137	regulation of response to DNA damage stimulus
L3Q65_01945	COG0800	Aldolase
L3Q65_01985	COG0765	amino acid transport
L3Q65_01990	COG0765	amino acid transport
L3Q65_01995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q65_02000	COG1126	abc transporter atp-binding protein
L3Q65_02010	COG0642	Histidine kinase
L3Q65_02025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L3Q65_02035	COG1196	nuclear chromosome segregation
L3Q65_02040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
L3Q65_02050	COG0525	valine-tRNA ligase activity
L3Q65_02065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L3Q65_02075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L3Q65_02085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
L3Q65_02090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3Q65_02130	COG1505	serine-type exopeptidase activity
L3Q65_02160	COG2936	dipeptidyl-peptidase activity
L3Q65_02165	COG2197	response regulator
L3Q65_02170	COG4585	Histidine kinase
L3Q65_02185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L3Q65_02190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L3Q65_02210	COG0123	including yeast histone deacetylase and acetoin utilization protein
L3Q65_02220	COG1960	acyl-CoA dehydrogenase activity
L3Q65_02225	COG1960	acyl-CoA dehydrogenase activity
L3Q65_02235	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_02245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L3Q65_02250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L3Q65_02310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_02345	COG0003	Pfam Anion-transporting ATPase
L3Q65_02355	COG1940	carbohydrate kinase activity
L3Q65_02370	COG1309	transcriptional regulator
L3Q65_02380	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
L3Q65_02405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L3Q65_02465	COG1946	Acyl-CoA thioesterase
L3Q65_02485	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
L3Q65_02485	COG1672	PFAM Archaeal ATPase
L3Q65_02490	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_02495	COG3226	Transcriptional regulator
L3Q65_02500	COG1960	acyl-CoA dehydrogenase activity
L3Q65_02505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_02535	COG2409	Drug exporters of the RND superfamily
L3Q65_02540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q65_02555	COG2018	Roadblock/LC7 domain
L3Q65_02570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L3Q65_02590	COG1703	isobutyryl-CoA mutase activity
L3Q65_02590	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
L3Q65_02590	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
L3Q65_02605	COG1960	acyl-CoA dehydrogenase activity
L3Q65_02610	COG1309	transcriptional regulator
L3Q65_02615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L3Q65_02645	COG0302	gtp cyclohydrolase
L3Q65_02650	COG0657	acetylesterase activity
L3Q65_02655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_02670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L3Q65_02675	COG1960	acyl-CoA dehydrogenase activity
L3Q65_02680	COG1960	acyl-CoA dehydrogenase activity
L3Q65_02685	COG2030	dehydratase
L3Q65_02705	COG0196	riboflavin kinase activity
L3Q65_02710	COG2030	dehydratase
L3Q65_02730	COG1053	succinate dehydrogenase
L3Q65_02740	COG1960	acyl-CoA dehydrogenase activity
L3Q65_02745	COG2267	carboxylic ester hydrolase activity
L3Q65_02750	COG0346	lactoylglutathione lyase activity
L3Q65_02755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q65_02785	COG2084	Dehydrogenase
L3Q65_02795	COG1846	Transcriptional regulator
L3Q65_02805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q65_02810	COG1228	amidohydrolase
L3Q65_02820	COG0596	Alpha beta hydrolase
L3Q65_02835	COG0183	Belongs to the thiolase family
L3Q65_02840	COG2124	cytochrome p450
L3Q65_02850	COG1295	ribonuclease BN
L3Q65_02875	COG1024	Enoyl-CoA hydratase
L3Q65_02885	COG2070	2-Nitropropane dioxygenase
L3Q65_02895	COG1846	Transcriptional regulator
L3Q65_02910	COG2188	Transcriptional regulator
L3Q65_02920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q65_02925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q65_02965	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L3Q65_02965	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L3Q65_02975	COG1490	D-aminoacyl-tRNA deacylase activity
L3Q65_02980	COG2890	protein-(glutamine-N5) methyltransferase activity
L3Q65_03000	COG2313	pseudouridylate synthase activity
L3Q65_03030	COG4213	ABC transporter substrate-binding protein
L3Q65_03040	COG4214	carbohydrate transport
L3Q65_03060	COG0174	glutamine synthetase
L3Q65_03075	COG1733	regulation of RNA biosynthetic process
L3Q65_03080	COG2910	NAD(P)H-binding
L3Q65_03085	COG0531	amino acid
L3Q65_03150	COG1940	carbohydrate kinase activity
L3Q65_03175	COG0756	dUTP diphosphatase activity
L3Q65_03205	COG0569	domain protein
L3Q65_03210	COG0531	amino acid
L3Q65_03215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L3Q65_03225	COG0823	Involved in the tonB-independent uptake of proteins
L3Q65_03225	COG4946	Tricorn protease homolog
L3Q65_03225	COG1506	peptidase
L3Q65_03240	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_03245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
L3Q65_03270	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_03275	COG0028	Belongs to the TPP enzyme family
L3Q65_03295	COG0745	RESPONSE REGULATOR receiver
L3Q65_03300	COG2205	protein histidine kinase activity
L3Q65_03325	COG1024	Enoyl-CoA hydratase
L3Q65_03325	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_03330	COG0183	Belongs to the thiolase family
L3Q65_03340	COG1024	Enoyl-CoA hydratase
L3Q65_03340	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_03350	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_03365	COG2197	response regulator
L3Q65_03375	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
L3Q65_03385	COG3253	May function as heme-dependent peroxidase
L3Q65_03390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_03405	COG3220	belongs to the UPF0276 family
L3Q65_03425	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L3Q65_03435	COG0515	serine threonine protein kinase
L3Q65_03435	COG2815	serine threonine protein kinase
L3Q65_03455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_03465	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L3Q65_03465	COG2508	Transcriptional regulator
L3Q65_03470	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_03475	COG0506	proline dehydrogenase activity
L3Q65_03480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3Q65_03490	COG1309	transcriptional regulator
L3Q65_03500	COG1793	dna ligase
L3Q65_03555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3Q65_03560	COG2326	polyphosphate kinase activity
L3Q65_03585	COG0174	glutamine synthetase
L3Q65_03600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
L3Q65_03630	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
L3Q65_03655	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L3Q65_03670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
L3Q65_03695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3Q65_03700	COG1263	PTS System
L3Q65_03705	COG2188	Transcriptional regulator
L3Q65_03710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3Q65_03745	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
L3Q65_03750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
L3Q65_03755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
L3Q65_03760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
L3Q65_03780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
L3Q65_03785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L3Q65_03795	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
L3Q65_03800	COG0540	Belongs to the ATCase OTCase family
L3Q65_03815	COG0505	Belongs to the CarA family
L3Q65_03825	COG0284	orotidine-5'-phosphate decarboxylase activity
L3Q65_03835	COG0194	GDP metabolic process
L3Q65_03840	COG1758	RNA polymerase activity
L3Q65_03850	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
L3Q65_03855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L3Q65_03880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3Q65_03895	COG0405	Gamma-glutamyltransferase
L3Q65_03905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L3Q65_03935	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_03935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_03940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
L3Q65_03960	COG0322	excinuclease ABC activity
L3Q65_03965	COG1660	Displays ATPase and GTPase activities
L3Q65_03970	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L3Q65_03975	COG1481	regulation of sporulation
L3Q65_03980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_03985	COG2133	pyrroloquinoline quinone binding
L3Q65_04020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L3Q65_04025	COG0126	phosphoglycerate kinase activity
L3Q65_04030	COG0149	triose-phosphate isomerase activity
L3Q65_04060	COG0363	glucosamine-6-phosphate deaminase activity
L3Q65_04075	COG0166	Belongs to the GPI family
L3Q65_04080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L3Q65_04090	COG0109	protoheme IX farnesyltransferase activity
L3Q65_04125	COG1612	heme a metabolic process
L3Q65_04135	COG1131	(ABC) transporter
L3Q65_04175	COG2151	metal-sulfur cluster biosynthetic enzyme
L3Q65_04190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L3Q65_04205	COG4585	Histidine kinase
L3Q65_04210	COG2197	response regulator
L3Q65_04215	COG2199	diguanylate cyclase activity
L3Q65_04215	COG2200	EAL domain
L3Q65_04220	COG0644	oxidoreductase
L3Q65_04255	COG0488	(ABC) transporter
L3Q65_04270	COG1132	(ABC) transporter
L3Q65_04275	COG4821	SIS domain
L3Q65_04280	COG2267	carboxylic ester hydrolase activity
L3Q65_04285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L3Q65_04290	COG1316	TRANSCRIPTIONal
L3Q65_04320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L3Q65_04330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3Q65_04335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
L3Q65_04335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3Q65_04360	COG1960	acyl-CoA dehydrogenase activity
L3Q65_04365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3Q65_04390	COG3469	chitinase activity
L3Q65_04410	COG1309	transcriptional regulator
L3Q65_04420	COG1309	transcriptional regulator
L3Q65_04425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_04430	COG0697	spore germination
L3Q65_04445	COG1733	regulation of RNA biosynthetic process
L3Q65_04460	COG0546	phosphoglycolate phosphatase activity
L3Q65_04470	COG2116	formate transmembrane transporter activity
L3Q65_04500	COG3119	arylsulfatase activity
L3Q65_04510	COG1846	Transcriptional regulator
L3Q65_04515	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_04550	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
L3Q65_04565	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_04570	COG0028	Belongs to the TPP enzyme family
L3Q65_04580	COG0477	Major facilitator Superfamily
L3Q65_04590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_04650	COG0402	S-adenosylhomocysteine deaminase activity
L3Q65_04670	COG2368	4-hydroxyphenylacetate
L3Q65_04695	COG1984	allophanate hydrolase subunit 2
L3Q65_04725	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
L3Q65_04745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
L3Q65_04765	COG1984	allophanate hydrolase subunit 2
L3Q65_04800	COG4552	Acetyltransferase involved in intracellular survival and related
L3Q65_04810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L3Q65_04840	COG0577	efflux transmembrane transporter activity
L3Q65_04850	COG2197	response regulator
L3Q65_04890	COG1940	carbohydrate kinase activity
L3Q65_04895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q65_04905	COG2186	Transcriptional regulator
L3Q65_04915	COG3209	COG3209 Rhs family protein
L3Q65_04920	COG3185	4-Hydroxyphenylpyruvate dioxygenase
L3Q65_04920	COG1082	Xylose isomerase domain protein TIM barrel
L3Q65_04925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
L3Q65_04930	COG1309	transcriptional regulator
L3Q65_04935	COG0477	Major facilitator Superfamily
L3Q65_04945	COG1063	alcohol dehydrogenase
L3Q65_04965	COG1472	Belongs to the glycosyl hydrolase 3 family
L3Q65_04980	COG1175	transmembrane transport
L3Q65_05000	COG0477	Major facilitator Superfamily
L3Q65_05005	COG3469	chitinase activity
L3Q65_05010	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L3Q65_05010	COG0456	acetyltransferase
L3Q65_05015	COG1960	acyl-CoA dehydrogenase activity
L3Q65_05020	COG1960	acyl-CoA dehydrogenase activity
L3Q65_05025	COG1960	acyl-CoA dehydrogenase activity
L3Q65_05045	COG4585	Histidine kinase
L3Q65_05050	COG2197	response regulator
L3Q65_05065	COG0484	heat shock protein binding
L3Q65_05080	COG0531	amino acid
L3Q65_05085	COG3250	beta-galactosidase activity
L3Q65_05095	COG0431	NADPH-dependent FMN reductase
L3Q65_05120	COG2124	cytochrome p450
L3Q65_05140	COG2226	methyltransferase
L3Q65_05145	COG0564	pseudouridine synthase activity
L3Q65_05155	COG1846	Transcriptional regulator
L3Q65_05165	COG0477	Major facilitator Superfamily
L3Q65_05175	COG1793	dna ligase
L3Q65_05215	COG2807	transmembrane transport
L3Q65_05235	COG0587	DNA-directed DNA polymerase activity
L3Q65_05240	COG0439	Biotin carboxylase
L3Q65_05245	COG1129	ABC transporter
L3Q65_05250	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3Q65_05270	COG2223	nitrite transmembrane transporter activity
L3Q65_05280	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_05290	COG0583	DNA-binding transcription factor activity
L3Q65_05310	COG0596	Alpha beta hydrolase
L3Q65_05325	COG0656	L-ascorbic acid biosynthetic process
L3Q65_05330	COG0297	glycogen (starch) synthase activity
L3Q65_05365	COG0069	glutamate synthase activity
L3Q65_05395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3Q65_05405	COG1131	(ABC) transporter
L3Q65_05430	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_05440	COG2890	protein-(glutamine-N5) methyltransferase activity
L3Q65_05445	COG0297	glycogen (starch) synthase activity
L3Q65_05450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L3Q65_05465	COG2188	Transcriptional regulator
L3Q65_05485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q65_05490	COG4608	Belongs to the ABC transporter superfamily
L3Q65_05505	COG0747	negative chemotaxis
L3Q65_05510	COG2186	Transcriptional regulator
L3Q65_05525	COG0673	inositol 2-dehydrogenase activity
L3Q65_05545	COG2205	protein histidine kinase activity
L3Q65_05550	COG0745	RESPONSE REGULATOR receiver
L3Q65_05560	COG4941	Belongs to the sigma-70 factor family
L3Q65_05565	COG3795	YCII-related domain
L3Q65_05610	COG1309	transcriptional regulator
L3Q65_05640	COG3260	NADH ubiquinone oxidoreductase 20
L3Q65_05660	COG0651	ATP synthesis coupled electron transport
L3Q65_05665	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
L3Q65_05665	COG3261	NADH dehydrogenase
L3Q65_05690	COG2124	cytochrome p450
L3Q65_05695	COG1309	transcriptional regulator
L3Q65_05710	COG2814	Major facilitator Superfamily
L3Q65_05765	COG2423	ornithine cyclodeaminase activity
L3Q65_05795	COG4106	trans-aconitate 2-methyltransferase activity
L3Q65_05805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_05820	COG0148	phosphopyruvate hydratase activity
L3Q65_05840	COG4991	sh3 domain protein
L3Q65_05875	COG2188	Transcriptional regulator
L3Q65_05895	COG0488	(ABC) transporter
L3Q65_05940	COG0583	DNA-binding transcription factor activity
L3Q65_05945	COG5006	permease, DMT superfamily
L3Q65_06000	COG1764	response to oxidative stress
L3Q65_06005	COG0583	DNA-binding transcription factor activity
L3Q65_06010	COG2814	Major facilitator Superfamily
L3Q65_06020	COG0072	phenylalanine-tRNA ligase activity
L3Q65_06040	COG1657	PFAM Prenyltransferase squalene oxidase
L3Q65_06050	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
L3Q65_06060	COG1562	ergosterol biosynthetic process
L3Q65_06065	COG3835	regulator
L3Q65_06070	COG0300	oxidoreductase activity
L3Q65_06080	COG0697	spore germination
L3Q65_06085	COG0438	transferase activity, transferring glycosyl groups
L3Q65_06095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L3Q65_06100	COG0583	DNA-binding transcription factor activity
L3Q65_06110	COG1119	ATPase activity
L3Q65_06150	COG1120	ATPase activity
L3Q65_06170	COG1126	abc transporter atp-binding protein
L3Q65_06180	COG0277	FAD linked oxidase domain protein
L3Q65_06185	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L3Q65_06215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_06220	COG1228	amidohydrolase
L3Q65_06230	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L3Q65_06235	COG1609	Transcriptional regulator
L3Q65_06245	COG0604	alcohol dehydrogenase
L3Q65_06245	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_06245	COG3321	synthase
L3Q65_06265	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_06290	COG3537	Alpha-1,2-mannosidase
L3Q65_06295	COG2814	Major facilitator Superfamily
L3Q65_06300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L3Q65_06365	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
L3Q65_06405	COG3629	intracellular signal transduction
L3Q65_06405	COG3903	Transcriptional regulator
L3Q65_06420	COG0477	Major facilitator Superfamily
L3Q65_06430	COG0387	Pfam Sodium calcium exchanger
L3Q65_06450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L3Q65_06480	COG2378	regulation of single-species biofilm formation
L3Q65_06495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q65_06505	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_06535	COG0535	radical SAM domain protein
L3Q65_06585	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_06590	COG1169	isochorismate synthase
L3Q65_06595	COG1021	2,3-dihydroxybenzoate-AMP ligase
L3Q65_06600	COG3433	isochorismatase activity
L3Q65_06600	COG1535	isochorismatase
L3Q65_06605	COG3433	isochorismatase activity
L3Q65_06605	COG1535	isochorismatase
L3Q65_06610	COG2375	cellular response to nickel ion
L3Q65_06620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3Q65_06625	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3Q65_06630	COG1120	ATPase activity
L3Q65_06645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L3Q65_06650	COG2197	response regulator
L3Q65_06655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q65_06660	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_06685	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_06690	COG1024	Enoyl-CoA hydratase
L3Q65_06700	COG1024	Enoyl-CoA hydratase
L3Q65_06705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L3Q65_06715	COG2271	Major facilitator Superfamily
L3Q65_06725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_06745	COG0477	Major facilitator Superfamily
L3Q65_06765	COG0438	transferase activity, transferring glycosyl groups
L3Q65_06775	COG2205	protein histidine kinase activity
L3Q65_06780	COG0745	RESPONSE REGULATOR receiver
L3Q65_06795	COG0477	Major facilitator Superfamily
L3Q65_06805	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_06810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q65_06815	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_06820	COG0477	Major facilitator Superfamily
L3Q65_06825	COG3962	Belongs to the TPP enzyme family
L3Q65_06830	COG3718	enzyme involved in inositol metabolism
L3Q65_06845	COG2188	Transcriptional regulator
L3Q65_06855	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
L3Q65_06865	COG0247	lactate metabolic process
L3Q65_06865	COG0277	FAD linked oxidase domain protein
L3Q65_06870	COG2186	Transcriptional regulator
L3Q65_06885	COG4447	cellulose binding
L3Q65_06905	COG0596	Alpha beta hydrolase
L3Q65_06910	COG0596	Alpha beta hydrolase
L3Q65_06925	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L3Q65_06955	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_06970	COG1176	ABC-type spermidine putrescine transport system, permease component I
L3Q65_06975	COG1177	transmembrane transport
L3Q65_07050	COG2261	transglycosylase associated protein
L3Q65_07055	COG1595	DNA-templated transcription, initiation
L3Q65_07060	COG2226	methyltransferase
L3Q65_07085	COG3511	phospholipase C
L3Q65_07095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_07110	COG0640	Transcriptional regulator
L3Q65_07145	COG1335	isochorismatase
L3Q65_07160	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_07170	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_07175	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
L3Q65_07225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L3Q65_07245	COG0765	amino acid transport
L3Q65_07250	COG0765	amino acid transport
L3Q65_07255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q65_07260	COG1126	abc transporter atp-binding protein
L3Q65_07275	COG1136	(ABC) transporter
L3Q65_07300	COG2072	flavoprotein involved in K transport
L3Q65_07320	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_07325	COG1454	alcohol dehydrogenase
L3Q65_07330	COG0531	amino acid
L3Q65_07385	COG0531	amino acid
L3Q65_07415	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_07420	COG0247	lactate metabolic process
L3Q65_07420	COG0277	FAD linked oxidase domain protein
L3Q65_07425	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_07430	COG0028	Belongs to the TPP enzyme family
L3Q65_07435	COG3387	PFAM Glycoside hydrolase 15-related
L3Q65_07445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
L3Q65_07450	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
L3Q65_07460	COG0306	phosphate transporter
L3Q65_07470	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_07510	COG1309	transcriptional regulator
L3Q65_07530	COG2259	Doxx family
L3Q65_07535	COG0156	8-amino-7-oxononanoate synthase activity
L3Q65_07540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
L3Q65_07560	COG2318	DinB family
L3Q65_07565	COG2226	methyltransferase
L3Q65_07590	COG1366	Belongs to the anti-sigma-factor antagonist family
L3Q65_07610	COG2890	protein-(glutamine-N5) methyltransferase activity
L3Q65_07625	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
L3Q65_07630	COG0778	Nitroreductase
L3Q65_07640	COG0477	Major facilitator Superfamily
L3Q65_07650	COG1733	regulation of RNA biosynthetic process
L3Q65_07655	COG0583	DNA-binding transcription factor activity
L3Q65_07660	COG0604	alcohol dehydrogenase
L3Q65_07690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_07695	COG0477	Major facilitator Superfamily
L3Q65_07720	COG1335	isochorismatase
L3Q65_07725	COG0596	Alpha beta hydrolase
L3Q65_07730	COG2309	aminopeptidase activity
L3Q65_07765	COG0243	molybdopterin cofactor binding
L3Q65_07790	COG0438	transferase activity, transferring glycosyl groups
L3Q65_07815	COG2192	nodulation
L3Q65_07820	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
L3Q65_07825	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
L3Q65_07825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
L3Q65_07830	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_07840	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L3Q65_07865	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L3Q65_07870	COG0859	PFAM glycosyl transferase family 9
L3Q65_07875	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_07900	COG0640	Transcriptional regulator
L3Q65_07920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
L3Q65_07935	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
L3Q65_07940	COG0515	serine threonine protein kinase
L3Q65_07945	COG1113	amino acid transport
L3Q65_07955	COG0583	DNA-binding transcription factor activity
L3Q65_07970	COG0640	Transcriptional regulator
L3Q65_07975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_07985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L3Q65_08000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_08005	COG0765	amino acid transport
L3Q65_08010	COG1126	abc transporter atp-binding protein
L3Q65_08030	COG0477	Major facilitator Superfamily
L3Q65_08040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3Q65_08080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3Q65_08080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3Q65_08085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3Q65_08095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L3Q65_08105	COG0667	Aldo Keto reductase
L3Q65_08110	COG1309	transcriptional regulator
L3Q65_08150	COG2197	response regulator
L3Q65_08180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_08220	COG0589	response to stress
L3Q65_08230	COG0517	IMP dehydrogenase activity
L3Q65_08230	COG0617	tRNA 3'-terminal CCA addition
L3Q65_08230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L3Q65_08290	COG1733	regulation of RNA biosynthetic process
L3Q65_08305	COG1309	transcriptional regulator
L3Q65_08315	COG3973	AAA domain
L3Q65_08320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L3Q65_08340	COG1132	(ABC) transporter
L3Q65_08345	COG1132	(ABC) transporter
L3Q65_08360	COG0515	serine threonine protein kinase
L3Q65_08385	COG1486	melibiose metabolic process
L3Q65_08395	COG0395	ABC-type sugar transport system, permease component
L3Q65_08410	COG0673	inositol 2-dehydrogenase activity
L3Q65_08420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L3Q65_08425	COG1105	Belongs to the carbohydrate kinase PfkB family
L3Q65_08430	COG0191	fructose-bisphosphate aldolase activity
L3Q65_08440	COG0402	S-adenosylhomocysteine deaminase activity
L3Q65_08445	COG1802	Transcriptional regulator
L3Q65_08450	COG0402	S-adenosylhomocysteine deaminase activity
L3Q65_08460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q65_08480	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_08495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_08505	COG0601	transmembrane transport
L3Q65_08510	COG0444	Belongs to the ABC transporter superfamily
L3Q65_08515	COG4608	Belongs to the ABC transporter superfamily
L3Q65_08550	COG3525	Glycosyl hydrolase, family 20, catalytic domain
L3Q65_08550	COG3291	Pkd domain containing protein
L3Q65_08585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_08605	COG0693	protein deglycase activity
L3Q65_08650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L3Q65_08670	COG0010	Belongs to the arginase family
L3Q65_08675	COG0765	amino acid transport
L3Q65_08680	COG1126	abc transporter atp-binding protein
L3Q65_08690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L3Q65_08700	COG0277	FAD linked oxidase domain protein
L3Q65_08715	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L3Q65_08730	COG0243	molybdopterin cofactor binding
L3Q65_08765	COG0366	Alpha amylase catalytic
L3Q65_08775	COG1175	transmembrane transport
L3Q65_08785	COG1609	Transcriptional regulator
L3Q65_08815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_08865	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_08865	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_08870	COG0431	NADPH-dependent FMN reductase
L3Q65_08890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_08915	COG1397	ADP-ribosylglycohydrolase
L3Q65_08920	COG2211	Major facilitator Superfamily
L3Q65_08970	COG0748	coenzyme F420 binding
L3Q65_08995	COG0604	alcohol dehydrogenase
L3Q65_09030	COG4172	Belongs to the ABC transporter superfamily
L3Q65_09035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_09040	COG0601	transmembrane transport
L3Q65_09055	COG1609	Transcriptional regulator
L3Q65_09105	COG0583	DNA-binding transcription factor activity
L3Q65_09110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_09115	COG2814	Major facilitator Superfamily
L3Q65_09125	COG1024	Enoyl-CoA hydratase
L3Q65_09130	COG1960	acyl-CoA dehydrogenase activity
L3Q65_09205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q65_09210	COG1414	Transcriptional regulator
L3Q65_09240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_09290	COG0596	Alpha beta hydrolase
L3Q65_09335	COG1181	Belongs to the D-alanine--D-alanine ligase family
L3Q65_09345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L3Q65_09360	COG0300	oxidoreductase activity
L3Q65_09360	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_09360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_09360	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_09360	COG3321	synthase
L3Q65_09365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L3Q65_09375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_09380	COG0477	Major facilitator Superfamily
L3Q65_09385	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_09390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3Q65_09415	COG0174	glutamine synthetase
L3Q65_09430	COG2124	cytochrome p450
L3Q65_09445	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_09455	COG1960	acyl-CoA dehydrogenase activity
L3Q65_09470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_09500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L3Q65_09510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3Q65_09525	COG3835	regulator
L3Q65_09530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_09545	COG1309	transcriptional regulator
L3Q65_09550	COG1819	glycosyl
L3Q65_09555	COG3629	intracellular signal transduction
L3Q65_09555	COG3903	Transcriptional regulator
L3Q65_09575	COG3629	intracellular signal transduction
L3Q65_09575	COG3903	Transcriptional regulator
L3Q65_09580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_09585	COG1657	PFAM Prenyltransferase squalene oxidase
L3Q65_09590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_09595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
L3Q65_09600	COG4585	Histidine kinase
L3Q65_09605	COG2197	response regulator
L3Q65_09620	COG3629	intracellular signal transduction
L3Q65_09625	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
L3Q65_09630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
L3Q65_09635	COG0142	geranyltranstransferase activity
L3Q65_09665	COG0129	dihydroxy-acid dehydratase activity
L3Q65_09700	COG2197	response regulator
L3Q65_09735	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_09755	COG0583	DNA-binding transcription factor activity
L3Q65_09765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q65_09775	COG2197	response regulator
L3Q65_09780	COG0154	amidase activity
L3Q65_09795	COG0747	negative chemotaxis
L3Q65_09800	COG0601	transmembrane transport
L3Q65_09805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_09810	COG0444	Belongs to the ABC transporter superfamily
L3Q65_09845	COG3284	Transcriptional regulator
L3Q65_09855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3Q65_09885	COG0459	protein refolding
L3Q65_09890	COG1024	Enoyl-CoA hydratase
L3Q65_09930	COG2159	amidohydrolase
L3Q65_09965	COG3842	ATPase activity
L3Q65_10000	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_10025	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3Q65_10030	COG1129	ABC transporter
L3Q65_10050	COG1082	Xylose isomerase domain protein TIM barrel
L3Q65_10070	COG1129	ABC transporter
L3Q65_10080	COG1082	Xylose isomerase domain protein TIM barrel
L3Q65_10085	COG0673	inositol 2-dehydrogenase activity
L3Q65_10090	COG1082	Xylose isomerase domain protein TIM barrel
L3Q65_10110	COG1175	transmembrane transport
L3Q65_10120	COG1940	carbohydrate kinase activity
L3Q65_10170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q65_10185	COG2814	Major facilitator Superfamily
L3Q65_10200	COG0477	Major facilitator Superfamily
L3Q65_10220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L3Q65_10225	COG1126	abc transporter atp-binding protein
L3Q65_10230	COG0765	amino acid transport
L3Q65_10235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q65_10270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q65_10270	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L3Q65_10300	COG0673	inositol 2-dehydrogenase activity
L3Q65_10315	COG1929	Belongs to the glycerate kinase type-1 family
L3Q65_10360	COG0145	ligase activity
L3Q65_10365	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
L3Q65_10370	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_10400	COG0277	FAD linked oxidase domain protein
L3Q65_10405	COG1063	alcohol dehydrogenase
L3Q65_10410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_10430	COG1960	acyl-CoA dehydrogenase activity
L3Q65_10525	COG1113	amino acid transport
L3Q65_10530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L3Q65_10540	COG1414	Transcriptional regulator
L3Q65_10570	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_10575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_10580	COG0686	Belongs to the AlaDH PNT family
L3Q65_10585	COG0280	phosphate acetyltransferase
L3Q65_10590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q65_10605	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
L3Q65_10605	COG1672	PFAM Archaeal ATPase
L3Q65_10640	COG0542	response to heat
L3Q65_10650	COG0515	serine threonine protein kinase
L3Q65_10655	COG2885	chlorophyll binding
L3Q65_10655	COG3047	cAMP biosynthetic process
L3Q65_10700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_10705	COG1335	isochorismatase
L3Q65_10710	COG0583	DNA-binding transcription factor activity
L3Q65_10735	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
L3Q65_10745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_10750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_10780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_10785	COG0601	transmembrane transport
L3Q65_10790	COG0747	negative chemotaxis
L3Q65_10800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L3Q65_10815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L3Q65_10830	COG0681	Belongs to the peptidase S26 family
L3Q65_10845	COG2327	Polysaccharide pyruvyl transferase
L3Q65_10850	COG0438	transferase activity, transferring glycosyl groups
L3Q65_10860	COG0438	transferase activity, transferring glycosyl groups
L3Q65_10880	COG1215	transferase activity, transferring glycosyl groups
L3Q65_10885	COG1024	Enoyl-CoA hydratase
L3Q65_10890	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
L3Q65_10895	COG1376	ErfK ybiS ycfS ynhG family protein
L3Q65_10910	COG4638	Rieske (2fe-2S)
L3Q65_10985	COG0656	L-ascorbic acid biosynthetic process
L3Q65_11005	COG1253	flavin adenine dinucleotide binding
L3Q65_11040	COG2267	carboxylic ester hydrolase activity
L3Q65_11045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L3Q65_11050	COG0583	DNA-binding transcription factor activity
L3Q65_11055	COG3572	ergothioneine biosynthetic process
L3Q65_11060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L3Q65_11065	COG0121	glutamine amidotransferase
L3Q65_11070	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
L3Q65_11105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L3Q65_11110	COG0791	NLP P60 protein
L3Q65_11110	COG3883	PFAM NLP P60 protein
L3Q65_11120	COG0746	molybdenum cofactor guanylyltransferase activity
L3Q65_11125	COG0714	Associated with various cellular activities
L3Q65_11135	COG2304	oxidoreductase activity
L3Q65_11145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L3Q65_11160	COG2205	protein histidine kinase activity
L3Q65_11170	COG0477	Major facilitator Superfamily
L3Q65_11180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
L3Q65_11195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
L3Q65_11205	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
L3Q65_11220	COG0789	Transcriptional regulator
L3Q65_11225	COG0215	cysteine-tRNA ligase activity
L3Q65_11230	COG0488	(ABC) transporter
L3Q65_11245	COG2814	Major facilitator Superfamily
L3Q65_11250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L3Q65_11265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q65_11270	COG0140	phosphoribosyl-ATP diphosphatase activity
L3Q65_11275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L3Q65_11280	COG1192	Involved in chromosome partitioning
L3Q65_11305	COG1994	Peptidase M50
L3Q65_11305	COG0517	IMP dehydrogenase activity
L3Q65_11325	COG1222	aaa ATPase
L3Q65_11365	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
L3Q65_11370	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
L3Q65_11380	COG4941	Belongs to the sigma-70 factor family
L3Q65_11385	COG3795	YCII-related domain
L3Q65_11400	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
L3Q65_11435	COG1597	lipid kinase activity
L3Q65_11450	COG4552	Acetyltransferase involved in intracellular survival and related
L3Q65_11460	COG4552	Acetyltransferase involved in intracellular survival and related
L3Q65_11470	COG2409	Drug exporters of the RND superfamily
L3Q65_11510	COG1309	transcriptional regulator
L3Q65_11515	COG4941	Belongs to the sigma-70 factor family
L3Q65_11525	COG4221	oxidoreductase activity
L3Q65_11530	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_11600	COG2255	four-way junction helicase activity
L3Q65_11615	COG2814	Major facilitator Superfamily
L3Q65_11630	COG0667	Aldo Keto reductase
L3Q65_11635	COG1063	alcohol dehydrogenase
L3Q65_11640	COG1574	metal-dependent hydrolase with the TIM-barrel fold
L3Q65_11645	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_11665	COG0601	transmembrane transport
L3Q65_11670	COG0444	Belongs to the ABC transporter superfamily
L3Q65_11675	COG4172	Belongs to the ABC transporter superfamily
L3Q65_11685	COG3209	COG3209 Rhs family protein
L3Q65_11700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_11715	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_11720	COG1960	acyl-CoA dehydrogenase activity
L3Q65_11765	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
L3Q65_11770	COG1140	nitrate reductase beta subunit
L3Q65_11795	COG1937	Protein conserved in bacteria
L3Q65_11815	COG2205	protein histidine kinase activity
L3Q65_11820	COG0745	RESPONSE REGULATOR receiver
L3Q65_11860	COG0446	pyridine nucleotide-disulphide oxidoreductase
L3Q65_11865	COG2920	part of a sulfur-relay system
L3Q65_11875	COG1830	Aldolase
L3Q65_11885	COG0674	pyruvate-flavodoxin oxidoreductase activity
L3Q65_11890	COG1013	pyruvate-flavodoxin oxidoreductase activity
L3Q65_11900	COG0492	ferredoxin-NADP+ reductase activity
L3Q65_11925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3Q65_11970	COG1042	CoA-binding domain protein
L3Q65_11970	COG0045	succinate-CoA ligase (ADP-forming) activity
L3Q65_11970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3Q65_11975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L3Q65_11990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L3Q65_11995	COG0574	Belongs to the PEP-utilizing enzyme family
L3Q65_11995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L3Q65_12005	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L3Q65_12005	COG0617	tRNA 3'-terminal CCA addition
L3Q65_12005	COG0517	IMP dehydrogenase activity
L3Q65_12015	COG1063	alcohol dehydrogenase
L3Q65_12050	COG1252	NADH dehydrogenase
L3Q65_12075	COG0517	IMP dehydrogenase activity
L3Q65_12075	COG0617	tRNA 3'-terminal CCA addition
L3Q65_12075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L3Q65_12080	COG2326	polyphosphate kinase activity
L3Q65_12115	COG0517	IMP dehydrogenase activity
L3Q65_12115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L3Q65_12115	COG0617	tRNA 3'-terminal CCA addition
L3Q65_12125	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
L3Q65_12140	COG4988	ABC transporter
L3Q65_12145	COG1294	oxidase, subunit
L3Q65_12150	COG1271	oxidase subunit
L3Q65_12190	COG1131	(ABC) transporter
L3Q65_12195	COG3559	Exporter of polyketide antibiotics
L3Q65_12200	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
L3Q65_12200	COG0778	Nitroreductase
L3Q65_12205	COG2239	Acts as a magnesium transporter
L3Q65_12215	COG0309	Hydrogenase expression formation protein (HypE)
L3Q65_12220	COG0409	Hydrogenase expression formation protein
L3Q65_12225	COG0298	carbon dioxide binding
L3Q65_12260	COG0589	response to stress
L3Q65_12270	COG0438	transferase activity, transferring glycosyl groups
L3Q65_12325	COG0531	amino acid
L3Q65_12335	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
L3Q65_12340	COG0549	Belongs to the carbamate kinase family
L3Q65_12355	COG2132	Multicopper oxidase
L3Q65_12365	COG0531	amino acid
L3Q65_12390	COG0038	chloride channel
L3Q65_12435	COG4214	carbohydrate transport
L3Q65_12440	COG1129	ABC transporter
L3Q65_12445	COG4213	ABC transporter substrate-binding protein
L3Q65_12450	COG2160	L-arabinose isomerase activity
L3Q65_12465	COG1609	Transcriptional regulator
L3Q65_12490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L3Q65_12495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3Q65_12500	COG3340	Belongs to the peptidase S51 family
L3Q65_12505	COG2271	Major facilitator Superfamily
L3Q65_12515	COG1053	succinate dehydrogenase
L3Q65_12520	COG0477	Major facilitator Superfamily
L3Q65_12525	COG2828	Protein conserved in bacteria
L3Q65_12540	COG0251	oxidation-reduction process
L3Q65_12555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L3Q65_12565	COG2205	protein histidine kinase activity
L3Q65_12570	COG0745	RESPONSE REGULATOR receiver
L3Q65_12580	COG0235	Class ii aldolase
L3Q65_12585	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_12610	COG1414	Transcriptional regulator
L3Q65_12615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_12625	COG0179	Fumarylacetoacetate (FAA) hydrolase
L3Q65_12635	COG1414	Transcriptional regulator
L3Q65_12650	COG2271	Major facilitator Superfamily
L3Q65_12655	COG3896	Chloramphenicol phosphotransferase-like protein
L3Q65_12670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_12680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3Q65_12690	COG0183	Belongs to the thiolase family
L3Q65_12695	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
L3Q65_12705	COG1960	acyl-CoA dehydrogenase activity
L3Q65_12715	COG1960	acyl-CoA dehydrogenase activity
L3Q65_12725	COG0154	amidase activity
L3Q65_12735	COG3104	oligopeptide transport
L3Q65_12740	COG1228	amidohydrolase
L3Q65_12830	COG0477	Major facilitator Superfamily
L3Q65_12835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_12840	COG1960	acyl-CoA dehydrogenase activity
L3Q65_12860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_12865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_12870	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L3Q65_12900	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_12900	COG3347	Dehydrogenase
L3Q65_12910	COG1073	alpha beta
L3Q65_12915	COG2197	response regulator
L3Q65_12935	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_12960	COG5564	TIM-barrel signal transduction protein
L3Q65_12960	COG2204	response regulator
L3Q65_13015	COG2318	DinB family
L3Q65_13065	COG0655	NAD(P)H dehydrogenase (quinone) activity
L3Q65_13070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_13125	COG3795	YCII-related domain
L3Q65_13130	COG0596	Alpha beta hydrolase
L3Q65_13145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L3Q65_13160	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_13165	COG1309	transcriptional regulator
L3Q65_13180	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
L3Q65_13185	COG0179	Fumarylacetoacetate (FAA) hydrolase
L3Q65_13195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_13200	COG2226	methyltransferase
L3Q65_13205	COG1960	acyl-CoA dehydrogenase activity
L3Q65_13210	COG1309	transcriptional regulator
L3Q65_13220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_13230	COG4221	oxidoreductase activity
L3Q65_13240	COG4974	Belongs to the 'phage' integrase family
L3Q65_13250	COG0789	Transcriptional regulator
L3Q65_13285	COG1435	thymidine kinase activity
L3Q65_13295	COG2814	Major facilitator Superfamily
L3Q65_13305	COG0640	Transcriptional regulator
L3Q65_13315	COG0463	Glycosyl transferase, family 2
L3Q65_13325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L3Q65_13330	COG1509	lysine 2,3-aminomutase activity
L3Q65_13335	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_13340	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_13345	COG2072	flavoprotein involved in K transport
L3Q65_13365	COG0657	acetylesterase activity
L3Q65_13370	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_13375	COG2072	flavoprotein involved in K transport
L3Q65_13380	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_13385	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_13400	COG2030	dehydratase
L3Q65_13400	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_13410	COG1073	alpha beta
L3Q65_13430	COG0145	ligase activity
L3Q65_13455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_13460	COG2070	2-Nitropropane dioxygenase
L3Q65_13465	COG1309	transcriptional regulator
L3Q65_13475	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_13485	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_13500	COG2267	carboxylic ester hydrolase activity
L3Q65_13530	COG0747	negative chemotaxis
L3Q65_13545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_13550	COG0601	transmembrane transport
L3Q65_13570	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_13575	COG1309	transcriptional regulator
L3Q65_13595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_13600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_13625	COG1024	Enoyl-CoA hydratase
L3Q65_13635	COG1960	acyl-CoA dehydrogenase activity
L3Q65_13640	COG1309	transcriptional regulator
L3Q65_13645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_13650	COG0183	Belongs to the thiolase family
L3Q65_13670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_13670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_13685	COG1073	alpha beta
L3Q65_13690	COG0477	Major facilitator Superfamily
L3Q65_13700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q65_13715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_13725	COG2186	Transcriptional regulator
L3Q65_13730	COG2301	Belongs to the HpcH HpaI aldolase family
L3Q65_13735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_13750	COG1063	alcohol dehydrogenase
L3Q65_13765	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3Q65_13775	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3Q65_13780	COG2197	response regulator
L3Q65_13785	COG0778	Nitroreductase
L3Q65_13800	COG2197	response regulator
L3Q65_13805	COG4585	Histidine kinase
L3Q65_13815	COG1357	PFAM Pentapeptide repeats (8 copies)
L3Q65_13905	COG0477	Major facilitator Superfamily
L3Q65_13935	COG0667	Aldo Keto reductase
L3Q65_13955	COG1506	peptidase
L3Q65_13955	COG0823	Involved in the tonB-independent uptake of proteins
L3Q65_13955	COG4946	Tricorn protease homolog
L3Q65_13960	COG1619	proteins homologs of microcin C7 resistance protein MccF
L3Q65_14020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_14025	COG0601	transmembrane transport
L3Q65_14030	COG4166	transmembrane transport
L3Q65_14040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3Q65_14055	COG3537	Alpha-1,2-mannosidase
L3Q65_14080	COG0667	Aldo Keto reductase
L3Q65_14100	COG1846	Transcriptional regulator
L3Q65_14110	COG0039	L-malate dehydrogenase activity
L3Q65_14115	COG0673	inositol 2-dehydrogenase activity
L3Q65_14140	COG0604	alcohol dehydrogenase
L3Q65_14140	COG3321	synthase
L3Q65_14150	COG3979	chitinase
L3Q65_14155	COG2271	Major facilitator Superfamily
L3Q65_14160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_14165	COG1733	regulation of RNA biosynthetic process
L3Q65_14175	COG0339	signal peptide processing
L3Q65_14185	COG1968	undecaprenyl-diphosphatase activity
L3Q65_14190	COG0667	Aldo Keto reductase
L3Q65_14210	COG4941	Belongs to the sigma-70 factor family
L3Q65_14240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3Q65_14245	COG1309	transcriptional regulator
L3Q65_14250	COG3246	L-lysine catabolic process to acetate
L3Q65_14255	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_14270	COG0601	transmembrane transport
L3Q65_14285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3Q65_14320	COG3285	dna ligase
L3Q65_14320	COG1793	dna ligase
L3Q65_14380	COG4221	oxidoreductase activity
L3Q65_14400	COG3960	tartronate-semialdehyde synthase activity
L3Q65_14405	COG2084	Dehydrogenase
L3Q65_14410	COG3622	Belongs to the hyi family
L3Q65_14415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L3Q65_14425	COG2850	peptidyl-arginine hydroxylation
L3Q65_14435	COG1802	Transcriptional regulator
L3Q65_14450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_14460	COG0045	succinate-CoA ligase (ADP-forming) activity
L3Q65_14475	COG1802	Transcriptional regulator
L3Q65_14480	COG1017	nitric oxide dioxygenase activity
L3Q65_14480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3Q65_14485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L3Q65_14500	COG0277	FAD linked oxidase domain protein
L3Q65_14515	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_14525	COG0583	DNA-binding transcription factor activity
L3Q65_14535	COG1053	succinate dehydrogenase
L3Q65_14540	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L3Q65_14555	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_14570	COG0583	DNA-binding transcription factor activity
L3Q65_14580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3Q65_14585	COG2072	flavoprotein involved in K transport
L3Q65_14615	COG0531	amino acid
L3Q65_14640	COG4172	Belongs to the ABC transporter superfamily
L3Q65_14645	COG0747	negative chemotaxis
L3Q65_14655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_14680	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_14705	COG2182	Extracellular solute-binding protein
L3Q65_14710	COG1175	transmembrane transport
L3Q65_14715	COG0395	ABC-type sugar transport system, permease component
L3Q65_14720	COG1472	Belongs to the glycosyl hydrolase 3 family
L3Q65_14725	COG4221	oxidoreductase activity
L3Q65_14775	COG2770	Histidine kinase
L3Q65_14775	COG2208	phosphoserine phosphatase activity
L3Q65_14795	COG0009	L-threonylcarbamoyladenylate synthase
L3Q65_14845	COG0456	acetyltransferase
L3Q65_14850	COG1063	alcohol dehydrogenase
L3Q65_14860	COG0778	Nitroreductase
L3Q65_14860	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
L3Q65_14910	COG1716	ATPase activity
L3Q65_14940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q65_14955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3Q65_14960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L3Q65_14960	COG1648	precorrin-2 dehydrogenase activity
L3Q65_14980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
L3Q65_14985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
L3Q65_14990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L3Q65_14995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
L3Q65_15005	COG0254	rRNA binding
L3Q65_15015	COG0523	cobalamin synthesis protein
L3Q65_15025	COG2814	Major facilitator Superfamily
L3Q65_15040	COG0076	glutamate decarboxylase activity
L3Q65_15045	COG2211	Major facilitator Superfamily
L3Q65_15050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_15075	COG1414	Transcriptional regulator
L3Q65_15085	COG1228	amidohydrolase
L3Q65_15115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_15125	COG1116	anion transmembrane transporter activity
L3Q65_15130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3Q65_15135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q65_15150	COG1132	(ABC) transporter
L3Q65_15160	COG1132	(ABC) transporter
L3Q65_15170	COG3486	L-lysine 6-monooxygenase (NADPH) activity
L3Q65_15175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3Q65_15175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L3Q65_15180	COG0488	(ABC) transporter
L3Q65_15190	COG1024	Enoyl-CoA hydratase
L3Q65_15235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L3Q65_15235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L3Q65_15285	COG0384	phenazine biosynthesis protein PhzF
L3Q65_15315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_15330	COG3251	PFAM MbtH domain protein
L3Q65_15340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
L3Q65_15345	COG0460	homoserine dehydrogenase
L3Q65_15365	COG3128	pkhd-type hydroxylase
L3Q65_15380	COG0475	glutathione-regulated potassium exporter activity
L3Q65_15430	COG1073	alpha beta
L3Q65_15445	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_15460	COG2124	cytochrome p450
L3Q65_15505	COG2508	Transcriptional regulator
L3Q65_15520	COG2271	Major facilitator Superfamily
L3Q65_15555	COG1902	pentaerythritol trinitrate reductase activity
L3Q65_15555	COG0446	pyridine nucleotide-disulphide oxidoreductase
L3Q65_15605	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_15620	COG0529	Catalyzes the synthesis of activated sulfate
L3Q65_15630	COG1515	deoxyribonuclease V activity
L3Q65_15655	COG2271	Major facilitator Superfamily
L3Q65_15675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L3Q65_15685	COG0577	efflux transmembrane transporter activity
L3Q65_15685	COG1136	(ABC) transporter
L3Q65_15700	COG1175	transmembrane transport
L3Q65_15725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L3Q65_15735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_15740	COG2301	Belongs to the HpcH HpaI aldolase family
L3Q65_15745	COG0477	Major facilitator Superfamily
L3Q65_15760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q65_15770	COG0604	alcohol dehydrogenase
L3Q65_15820	COG1733	regulation of RNA biosynthetic process
L3Q65_15835	COG0671	phosphoesterase, PA-phosphatase related
L3Q65_15840	COG0704	Plays a role in the regulation of phosphate uptake
L3Q65_15855	COG1472	Belongs to the glycosyl hydrolase 3 family
L3Q65_15860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L3Q65_15865	COG1595	DNA-templated transcription, initiation
L3Q65_15905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L3Q65_15910	COG0640	Transcriptional regulator
L3Q65_15915	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L3Q65_15920	COG1285	pathogenesis
L3Q65_15930	COG1116	anion transmembrane transporter activity
L3Q65_15935	COG2814	Major facilitator Superfamily
L3Q65_15955	COG2814	Major facilitator Superfamily
L3Q65_15975	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
L3Q65_15990	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L3Q65_16000	COG0628	permease
L3Q65_16005	COG2909	trisaccharide binding
L3Q65_16050	COG2814	Major facilitator Superfamily
L3Q65_16055	COG3387	PFAM Glycoside hydrolase 15-related
L3Q65_16090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L3Q65_16100	COG3250	beta-galactosidase activity
L3Q65_16110	COG1695	Transcriptional regulator
L3Q65_16115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_16145	COG1376	ErfK ybiS ycfS ynhG family protein
L3Q65_16175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_16190	COG1793	dna ligase
L3Q65_16190	COG3285	dna ligase
L3Q65_16260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_16265	COG0596	Alpha beta hydrolase
L3Q65_16280	COG0515	serine threonine protein kinase
L3Q65_16280	COG2815	serine threonine protein kinase
L3Q65_16305	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L3Q65_16315	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
L3Q65_16345	COG0028	Belongs to the TPP enzyme family
L3Q65_16390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q65_16435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L3Q65_16440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L3Q65_16445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L3Q65_16455	COG1862	Preprotein translocase
L3Q65_16460	COG2255	four-way junction helicase activity
L3Q65_16465	COG0632	four-way junction helicase activity
L3Q65_16470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
L3Q65_16485	COG0217	transcriptional regulatory protein
L3Q65_16490	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
L3Q65_16495	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
L3Q65_16500	COG3629	intracellular signal transduction
L3Q65_16500	COG3903	Transcriptional regulator
L3Q65_16525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L3Q65_16530	COG1940	carbohydrate kinase activity
L3Q65_16560	COG1175	transmembrane transport
L3Q65_16565	COG0395	ABC-type sugar transport system, permease component
L3Q65_16570	COG3842	ATPase activity
L3Q65_16580	COG1349	DNA-binding transcription factor activity
L3Q65_16630	COG1396	sequence-specific DNA binding
L3Q65_16655	COG3608	succinylglutamate desuccinylase aspartoacylase
L3Q65_16655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
L3Q65_16665	COG0438	transferase activity, transferring glycosyl groups
L3Q65_16670	COG1560	Kdo2-lipid A biosynthetic process
L3Q65_16680	COG1846	Transcriptional regulator
L3Q65_16695	COG0778	Nitroreductase
L3Q65_16715	COG2197	response regulator
L3Q65_16735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L3Q65_16735	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L3Q65_16735	COG3321	synthase
L3Q65_16735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3Q65_16740	COG1960	acyl-CoA dehydrogenase activity
L3Q65_16745	COG1960	acyl-CoA dehydrogenase activity
L3Q65_16760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3Q65_16785	COG4221	oxidoreductase activity
L3Q65_16790	COG1834	amidinotransferase
L3Q65_16855	COG1073	alpha beta
L3Q65_16865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_16895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L3Q65_16915	COG0300	oxidoreductase activity
L3Q65_16960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L3Q65_16965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L3Q65_16970	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_16970	COG1024	Enoyl-CoA hydratase
L3Q65_16980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
L3Q65_16995	COG0129	dihydroxy-acid dehydratase activity
L3Q65_17015	COG1335	isochorismatase
L3Q65_17025	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_17030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3Q65_17040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
L3Q65_17050	COG0366	Alpha amylase catalytic
L3Q65_17055	COG0366	Alpha amylase catalytic
L3Q65_17065	COG2378	regulation of single-species biofilm formation
L3Q65_17105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
L3Q65_17120	COG1802	Transcriptional regulator
L3Q65_17185	COG1088	dTDP-glucose 4,6-dehydratase activity
L3Q65_17200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L3Q65_17215	COG0714	Associated with various cellular activities
L3Q65_17225	COG3552	Protein containing von Willebrand factor type A (VWA) domain
L3Q65_17230	COG0789	Transcriptional regulator
L3Q65_17245	COG0346	lactoylglutathione lyase activity
L3Q65_17275	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_17280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q65_17285	COG1414	Transcriptional regulator
L3Q65_17290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3Q65_17330	COG1160	GTP binding
L3Q65_17340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
L3Q65_17355	COG0475	glutathione-regulated potassium exporter activity
L3Q65_17360	COG2936	dipeptidyl-peptidase activity
L3Q65_17370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L3Q65_17395	COG0494	nUDIX hydrolase
L3Q65_17400	COG0504	CTP synthase activity
L3Q65_17405	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L3Q65_17415	COG1802	Transcriptional regulator
L3Q65_17420	COG1953	Uracil, thiamine, allantoin
L3Q65_17460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L3Q65_17475	COG0647	UMP catabolic process
L3Q65_17505	COG2094	Belongs to the DNA glycosylase MPG family
L3Q65_17510	COG0165	Argininosuccinate lyase
L3Q65_17515	COG0137	argininosuccinate synthase activity
L3Q65_17520	COG1438	arginine binding
L3Q65_17525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
L3Q65_17530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3Q65_17535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
L3Q65_17540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L3Q65_17545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
L3Q65_17565	COG0072	phenylalanine-tRNA ligase activity
L3Q65_17565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3Q65_17570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
L3Q65_17575	COG0563	adenylate kinase activity
L3Q65_17580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3Q65_17585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
L3Q65_17590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
L3Q65_17610	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L3Q65_17615	COG0251	oxidation-reduction process
L3Q65_17635	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
L3Q65_17640	COG2610	gluconate transmembrane transporter activity
L3Q65_17645	COG2706	6-phosphogluconolactonase activity
L3Q65_17655	COG1175	transmembrane transport
L3Q65_17660	COG0395	ABC-type sugar transport system, permease component
L3Q65_17675	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_17680	COG4565	transcriptional regulatory protein
L3Q65_17685	COG3290	protein histidine kinase activity
L3Q65_17690	COG1301	dicarboxylic acid transport
L3Q65_17695	COG1733	regulation of RNA biosynthetic process
L3Q65_17720	COG0328	RNA-DNA hybrid ribonuclease activity
L3Q65_17730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q65_17750	COG0328	RNA-DNA hybrid ribonuclease activity
L3Q65_17760	COG3012	SEC-C Motif Domain Protein
L3Q65_17765	COG3250	beta-galactosidase activity
L3Q65_17770	COG2272	Belongs to the type-B carboxylesterase lipase family
L3Q65_17775	COG0025	NhaP-type Na H and K H
L3Q65_17780	COG0406	alpha-ribazole phosphatase activity
L3Q65_17805	COG1070	Carbohydrate kinase
L3Q65_17810	COG1609	Transcriptional regulator
L3Q65_17825	COG0823	Involved in the tonB-independent uptake of proteins
L3Q65_17825	COG4946	Tricorn protease homolog
L3Q65_17825	COG1506	peptidase
L3Q65_17835	COG1131	(ABC) transporter
L3Q65_17910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L3Q65_17915	COG0237	dephospho-CoA kinase activity
L3Q65_17915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L3Q65_17940	COG2226	methyltransferase
L3Q65_17955	COG1511	domain protein
L3Q65_17965	COG1653	transport
L3Q65_18120	COG3706	GGDEF domain
L3Q65_18130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
L3Q65_18205	COG3883	PFAM NLP P60 protein
L3Q65_18205	COG0791	NLP P60 protein
L3Q65_18415	COG0179	Fumarylacetoacetate (FAA) hydrolase
L3Q65_18420	COG2188	Transcriptional regulator
L3Q65_18450	COG3473	Maleate cis-trans isomerase
L3Q65_18460	COG1021	2,3-dihydroxybenzoate-AMP ligase
L3Q65_18465	COG1309	transcriptional regulator
L3Q65_18475	COG0667	Aldo Keto reductase
L3Q65_18505	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_18510	COG2814	Major facilitator Superfamily
L3Q65_18530	COG2814	Major facilitator Superfamily
L3Q65_18585	COG2770	Histidine kinase
L3Q65_18585	COG2208	phosphoserine phosphatase activity
L3Q65_18605	COG1366	Belongs to the anti-sigma-factor antagonist family
L3Q65_18615	COG0693	protein deglycase activity
L3Q65_18630	COG0492	ferredoxin-NADP+ reductase activity
L3Q65_18640	COG1687	branched-chain amino acid
L3Q65_18645	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L3Q65_18650	COG1522	sequence-specific DNA binding
L3Q65_18670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_18670	COG3321	synthase
L3Q65_18675	COG0300	oxidoreductase activity
L3Q65_18680	COG0477	Major facilitator Superfamily
L3Q65_18700	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_18730	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_18735	COG0477	Major facilitator Superfamily
L3Q65_18745	COG0252	asparaginase activity
L3Q65_18750	COG1609	Transcriptional regulator
L3Q65_18760	COG1982	Orn Lys Arg decarboxylase major
L3Q65_18775	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
L3Q65_18830	COG3546	catalase activity
L3Q65_18835	COG0723	plastoquinol--plastocyanin reductase activity
L3Q65_18850	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_18865	COG0247	lactate metabolic process
L3Q65_18865	COG0277	FAD linked oxidase domain protein
L3Q65_18870	COG1454	alcohol dehydrogenase
L3Q65_18875	COG0477	Major facilitator Superfamily
L3Q65_18915	COG1659	Linocin_M18 bacteriocin protein
L3Q65_18940	COG0437	4 iron, 4 sulfur cluster binding
L3Q65_18955	COG1921	L-seryl-tRNASec selenium transferase activity
L3Q65_18965	COG0709	Synthesizes selenophosphate from selenide and ATP
L3Q65_19000	COG1007	ATP synthesis coupled electron transport
L3Q65_19010	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
L3Q65_19015	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L3Q65_19035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q65_19060	COG1309	transcriptional regulator
L3Q65_19065	COG1609	Transcriptional regulator
L3Q65_19070	COG2807	transmembrane transport
L3Q65_19075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_19075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q65_19085	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
L3Q65_19085	COG0778	Nitroreductase
L3Q65_19110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L3Q65_19115	COG1376	ErfK ybiS ycfS ynhG family protein
L3Q65_19160	COG2855	membrane
L3Q65_19165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_19170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_19175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_19195	COG2814	Major facilitator Superfamily
L3Q65_19220	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
L3Q65_19225	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
L3Q65_19265	COG1309	transcriptional regulator
L3Q65_19270	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_19275	COG0183	Belongs to the thiolase family
L3Q65_19300	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_19305	COG0183	Belongs to the thiolase family
L3Q65_19310	COG2030	dehydratase
L3Q65_19315	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19320	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19325	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19330	COG0183	Belongs to the thiolase family
L3Q65_19335	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_19345	COG2030	dehydratase
L3Q65_19350	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_19355	COG1024	Enoyl-CoA hydratase
L3Q65_19375	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19380	COG1024	Enoyl-CoA hydratase
L3Q65_19385	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19390	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19395	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19415	COG1309	transcriptional regulator
L3Q65_19420	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_19425	COG0183	Belongs to the thiolase family
L3Q65_19430	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_19435	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_19440	COG1309	transcriptional regulator
L3Q65_19445	COG1064	alcohol dehydrogenase
L3Q65_19465	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_19480	COG1309	transcriptional regulator
L3Q65_19500	COG1505	serine-type exopeptidase activity
L3Q65_19510	COG0477	Major facilitator Superfamily
L3Q65_19520	COG0346	lactoylglutathione lyase activity
L3Q65_19530	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_19540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_19575	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_19585	COG1053	succinate dehydrogenase
L3Q65_19595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q65_19630	COG0581	inorganic phosphate transmembrane transporter activity
L3Q65_19640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L3Q65_19645	COG2346	COG2346, Truncated hemoglobins
L3Q65_19650	COG1733	regulation of RNA biosynthetic process
L3Q65_19690	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_19705	COG4638	Rieske (2fe-2S)
L3Q65_19710	COG0583	DNA-binding transcription factor activity
L3Q65_19715	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_19720	COG3485	protocatechuate 3,4-dioxygenase
L3Q65_19725	COG4829	muconolactone delta-isomerase
L3Q65_19730	COG1136	(ABC) transporter
L3Q65_19735	COG0577	efflux transmembrane transporter activity
L3Q65_19735	COG1136	(ABC) transporter
L3Q65_19745	COG1024	Enoyl-CoA hydratase
L3Q65_19760	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19765	COG1960	acyl-CoA dehydrogenase activity
L3Q65_19770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q65_19840	COG0745	RESPONSE REGULATOR receiver
L3Q65_19845	COG2205	protein histidine kinase activity
L3Q65_19855	COG1309	transcriptional regulator
L3Q65_19860	COG0644	oxidoreductase
L3Q65_19890	COG0514	ATP-dependent DNA helicase (RecQ)
L3Q65_19900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L3Q65_19910	COG0542	response to heat
L3Q65_19935	COG0667	Aldo Keto reductase
L3Q65_19955	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
L3Q65_19960	COG1846	Transcriptional regulator
L3Q65_19960	COG1940	carbohydrate kinase activity
L3Q65_19985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_20010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
L3Q65_20015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L3Q65_20025	COG0640	Transcriptional regulator
L3Q65_20030	COG0768	penicillin binding
L3Q65_20035	COG1113	amino acid transport
L3Q65_20040	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L3Q65_20045	COG0326	Molecular chaperone. Has ATPase activity
L3Q65_20060	COG0640	Transcriptional regulator
L3Q65_20080	COG1799	cell septum assembly
L3Q65_20090	COG1496	oxidoreductase activity
L3Q65_20095	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L3Q65_20105	COG1595	DNA-templated transcription, initiation
L3Q65_20120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L3Q65_20135	COG2318	DinB family
L3Q65_20150	COG0702	epimerase
L3Q65_20160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L3Q65_20165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
L3Q65_20175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
L3Q65_20180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L3Q65_20195	COG0768	penicillin binding
L3Q65_20205	COG0275	rRNA processing
L3Q65_20210	COG2001	Belongs to the MraZ family
L3Q65_20235	COG0714	Associated with various cellular activities
L3Q65_20245	COG1305	Transglutaminase-like
L3Q65_20255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L3Q65_20265	COG1192	Involved in chromosome partitioning
L3Q65_20270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L3Q65_20280	COG0167	dihydroorotate dehydrogenase activity
L3Q65_20295	COG1842	Phage shock protein A
L3Q65_20300	COG1396	sequence-specific DNA binding
L3Q65_20305	COG1058	Belongs to the CinA family
L3Q65_20305	COG1546	Belongs to the CinA family
L3Q65_20315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L3Q65_20320	COG0464	growth
L3Q65_20325	COG2755	lipolytic protein G-D-S-L family
L3Q65_20325	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
L3Q65_20330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
L3Q65_20340	COG1674	ftsk spoiiie
L3Q65_20360	COG0655	NAD(P)H dehydrogenase (quinone) activity
L3Q65_20370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L3Q65_20375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q65_20395	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
L3Q65_20410	COG3214	Protein conserved in bacteria
L3Q65_20435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
L3Q65_20440	COG0612	Peptidase, M16
L3Q65_20445	COG1185	polyribonucleotide nucleotidyltransferase activity
L3Q65_20450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
L3Q65_20470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L3Q65_20480	COG0384	phenazine biosynthesis protein PhzF
L3Q65_20495	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L3Q65_20515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
L3Q65_20540	COG0779	Required for maturation of 30S ribosomal subunits
L3Q65_20575	COG3851	Histidine kinase
L3Q65_20580	COG2197	response regulator
L3Q65_20595	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_20605	COG1053	succinate dehydrogenase
L3Q65_20615	COG1846	Transcriptional regulator
L3Q65_20640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L3Q65_20650	COG1733	regulation of RNA biosynthetic process
L3Q65_20665	COG0745	RESPONSE REGULATOR receiver
L3Q65_20670	COG5002	protein histidine kinase activity
L3Q65_20675	COG1316	TRANSCRIPTIONal
L3Q65_20715	COG0583	DNA-binding transcription factor activity
L3Q65_20740	COG1136	(ABC) transporter
L3Q65_20750	COG2197	response regulator
L3Q65_20780	COG1674	ftsk spoiiie
L3Q65_20800	COG0464	growth
L3Q65_20865	COG1609	Transcriptional regulator
L3Q65_20930	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
L3Q65_21010	COG2116	formate transmembrane transporter activity
L3Q65_21025	COG0583	DNA-binding transcription factor activity
L3Q65_21040	COG1309	transcriptional regulator
L3Q65_21105	COG0640	Transcriptional regulator
L3Q65_21135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
L3Q65_21155	COG0789	Transcriptional regulator
L3Q65_21160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L3Q65_21165	COG0667	Aldo Keto reductase
L3Q65_21175	COG3973	AAA domain
L3Q65_21200	COG2084	Dehydrogenase
L3Q65_21230	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
L3Q65_21235	COG2080	2 iron, 2 sulfur cluster binding
L3Q65_21305	COG3285	dna ligase
L3Q65_21305	COG1793	dna ligase
L3Q65_21330	COG0542	response to heat
L3Q65_21345	COG3706	GGDEF domain
L3Q65_21365	COG1051	belongs to the nudix hydrolase family
L3Q65_21385	COG3794	PFAM blue (type 1) copper domain protein
L3Q65_21440	COG4585	Histidine kinase
L3Q65_21475	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
L3Q65_21500	COG2814	Major facilitator Superfamily
L3Q65_21555	COG2226	methyltransferase
L3Q65_21585	COG4106	trans-aconitate 2-methyltransferase activity
L3Q65_21600	COG1595	DNA-templated transcription, initiation
L3Q65_21620	COG0232	Belongs to the dGTPase family. Type 2 subfamily
L3Q65_21630	COG2197	response regulator
L3Q65_21635	COG4585	Histidine kinase
L3Q65_21645	COG1131	(ABC) transporter
L3Q65_21650	COG0423	glycine-tRNA ligase activity
L3Q65_21685	COG0701	Predicted permease
L3Q65_21695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L3Q65_21700	COG1381	Involved in DNA repair and RecF pathway recombination
L3Q65_21710	COG1714	RDD family
L3Q65_21725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L3Q65_21740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
L3Q65_21750	COG0537	adenosine 5'-monophosphoramidase activity
L3Q65_21760	COG0484	heat shock protein binding
L3Q65_21820	COG2205	protein histidine kinase activity
L3Q65_21825	COG0745	RESPONSE REGULATOR receiver
L3Q65_21830	COG1953	Uracil, thiamine, allantoin
L3Q65_21840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L3Q65_21905	COG4221	oxidoreductase activity
L3Q65_21930	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L3Q65_21950	COG0604	alcohol dehydrogenase
L3Q65_21960	COG0531	amino acid
L3Q65_21980	COG0481	GTPase activity
L3Q65_21985	COG2226	methyltransferase
L3Q65_22000	COG0268	Binds directly to 16S ribosomal RNA
L3Q65_22010	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L3Q65_22015	COG2333	competence protein COMEC
L3Q65_22015	COG0658	competence protein
L3Q65_22020	COG1555	photosystem II stabilization
L3Q65_22030	COG1307	EDD domain protein, DegV family
L3Q65_22035	COG2755	lipolytic protein G-D-S-L family
L3Q65_22040	COG0406	alpha-ribazole phosphatase activity
L3Q65_22045	COG0799	negative regulation of ribosome biogenesis
L3Q65_22050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
L3Q65_22060	COG0477	Major facilitator Superfamily
L3Q65_22065	COG0018	arginyl-trna synthetase
L3Q65_22070	COG1309	transcriptional regulator
L3Q65_22075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L3Q65_22080	COG1960	acyl-CoA dehydrogenase activity
L3Q65_22085	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_22090	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_22105	COG1309	transcriptional regulator
L3Q65_22115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
L3Q65_22125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
L3Q65_22130	COG1530	ribonuclease E activity
L3Q65_22130	COG1530	ribonuclease E activity
L3Q65_22150	COG1131	(ABC) transporter
L3Q65_22175	COG0105	UTP biosynthetic process
L3Q65_22260	COG0454	-acetyltransferase
L3Q65_22260	COG0456	acetyltransferase
L3Q65_22280	COG0285	dihydrofolate synthase activity
L3Q65_22295	COG2801	Transposase and inactivated derivatives
L3Q65_22305	COG0525	valine-tRNA ligase activity
L3Q65_22320	COG0477	Major facilitator Superfamily
L3Q65_22330	COG1316	TRANSCRIPTIONal
L3Q65_22375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L3Q65_22385	COG1309	transcriptional regulator
L3Q65_22405	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
L3Q65_22410	COG0740	serine-type endopeptidase activity
L3Q65_22420	COG0544	peptidyl-prolyl cis-trans isomerase activity
L3Q65_22425	COG3001	Fructosamine kinase
L3Q65_22435	COG2205	protein histidine kinase activity
L3Q65_22440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
L3Q65_22450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
L3Q65_22500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L3Q65_22505	COG0702	epimerase
L3Q65_22510	COG1733	regulation of RNA biosynthetic process
L3Q65_22520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
L3Q65_22545	COG1609	Transcriptional regulator
L3Q65_22555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L3Q65_22575	COG1785	Belongs to the alkaline phosphatase family
L3Q65_22585	COG1940	carbohydrate kinase activity
L3Q65_22595	COG0017	Asparaginyl-tRNA synthetase
L3Q65_22600	COG1846	Transcriptional regulator
L3Q65_22625	COG5002	protein histidine kinase activity
L3Q65_22625	COG0784	Response regulator, receiver
L3Q65_22695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_22700	COG2223	nitrite transmembrane transporter activity
L3Q65_22705	COG0154	amidase activity
L3Q65_22710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L3Q65_22810	COG3629	intracellular signal transduction
L3Q65_22810	COG3903	Transcriptional regulator
L3Q65_22835	COG2271	Major facilitator Superfamily
L3Q65_22840	COG0251	oxidation-reduction process
L3Q65_22860	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_22865	COG0583	DNA-binding transcription factor activity
L3Q65_22885	COG2197	response regulator
L3Q65_22890	COG4585	Histidine kinase
L3Q65_22925	COG1309	transcriptional regulator
L3Q65_22935	COG0702	epimerase
L3Q65_22945	COG0702	epimerase
L3Q65_22995	COG1846	Transcriptional regulator
L3Q65_23025	COG0698	ribose 5-phosphate isomerase
L3Q65_23040	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L3Q65_23050	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L3Q65_23075	COG0668	transmembrane transport
L3Q65_23085	COG0366	Alpha amylase catalytic
L3Q65_23095	COG1278	Cold shock
L3Q65_23125	COG2902	Dehydrogenase
L3Q65_23145	COG1609	Transcriptional regulator
L3Q65_23175	COG2423	ornithine cyclodeaminase activity
L3Q65_23185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L3Q65_23200	COG0372	Belongs to the citrate synthase family
L3Q65_23235	COG0604	alcohol dehydrogenase
L3Q65_23235	COG3321	synthase
L3Q65_23285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_23290	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_23325	COG3209	COG3209 Rhs family protein
L3Q65_23345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_23350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3Q65_23360	COG1960	acyl-CoA dehydrogenase activity
L3Q65_23390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L3Q65_23415	COG4941	Belongs to the sigma-70 factor family
L3Q65_23420	COG3795	YCII-related domain
L3Q65_23435	COG0009	L-threonylcarbamoyladenylate synthase
L3Q65_23440	COG1285	pathogenesis
L3Q65_23450	COG1937	Protein conserved in bacteria
L3Q65_23460	COG2608	mercury ion transmembrane transporter activity
L3Q65_23495	COG0596	Alpha beta hydrolase
L3Q65_23500	COG0596	Alpha beta hydrolase
L3Q65_23505	COG4221	oxidoreductase activity
L3Q65_23520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
L3Q65_23610	COG0745	RESPONSE REGULATOR receiver
L3Q65_23615	COG0642	Histidine kinase
L3Q65_23620	COG0531	amino acid
L3Q65_23625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L3Q65_23685	COG1024	Enoyl-CoA hydratase
L3Q65_23715	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_23730	COG1643	Atp-dependent helicase
L3Q65_23735	COG0475	glutathione-regulated potassium exporter activity
L3Q65_23755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L3Q65_23755	COG1796	DNA polymerase
L3Q65_23765	COG1802	Transcriptional regulator
L3Q65_23800	COG3795	YCII-related domain
L3Q65_23805	COG4941	Belongs to the sigma-70 factor family
L3Q65_23810	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
L3Q65_23815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3Q65_23835	COG1609	Transcriptional regulator
L3Q65_23850	COG2233	PERMEase
L3Q65_23855	COG2233	PERMEase
L3Q65_23860	COG0163	prenyltransferase activity
L3Q65_23865	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
L3Q65_23870	COG0523	cobalamin synthesis protein
L3Q65_23880	COG0235	Class ii aldolase
L3Q65_23880	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
L3Q65_23910	COG1846	Transcriptional regulator
L3Q65_23915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_23920	COG0477	Major facilitator Superfamily
L3Q65_23945	COG1739	Uncharacterized protein family UPF0029
L3Q65_23950	COG0069	glutamate synthase activity
L3Q65_23950	COG0067	glutamate synthase
L3Q65_23950	COG0070	glutamate synthase
L3Q65_23960	COG1228	amidohydrolase
L3Q65_23965	COG0477	Major facilitator Superfamily
L3Q65_23970	COG0583	DNA-binding transcription factor activity
L3Q65_23995	COG3851	Histidine kinase
L3Q65_24000	COG2197	response regulator
L3Q65_24005	COG1492	cobalamin metabolic process
L3Q65_24010	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
L3Q65_24020	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L3Q65_24025	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
L3Q65_24040	COG1797	cobyrinic acid a,c-diamide synthase activity
L3Q65_24075	COG0778	Nitroreductase
L3Q65_24085	COG2223	nitrite transmembrane transporter activity
L3Q65_24090	COG2207	Transcriptional regulator
L3Q65_24115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q65_24120	COG1131	(ABC) transporter
L3Q65_24130	COG1476	TRANSCRIPTIONal
L3Q65_24140	COG3469	chitinase activity
L3Q65_24145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L3Q65_24145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L3Q65_24150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
L3Q65_24165	COG2226	methyltransferase
L3Q65_24190	COG0433	COG0433 Predicted ATPase
L3Q65_24195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L3Q65_24240	COG2267	carboxylic ester hydrolase activity
L3Q65_24245	COG0346	lactoylglutathione lyase activity
L3Q65_24250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_24265	COG2409	Drug exporters of the RND superfamily
L3Q65_24355	COG3344	reverse transcriptase
L3Q65_24375	COG4552	Acetyltransferase involved in intracellular survival and related
L3Q65_24385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L3Q65_24395	COG1063	alcohol dehydrogenase
L3Q65_24410	COG0644	oxidoreductase
L3Q65_24425	COG0726	polysaccharide deacetylase
L3Q65_24430	COG2223	nitrite transmembrane transporter activity
L3Q65_24435	COG2188	Transcriptional regulator
L3Q65_24560	COG1857	crispr-associated protein
L3Q65_24610	COG1494	fructose-1,6-bisphosphatase
L3Q65_24640	COG3279	Response regulator of the LytR AlgR family
L3Q65_24640	COG5000	phosphorelay sensor kinase activity
L3Q65_24655	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
L3Q65_24660	COG1971	Probably functions as a manganese efflux pump
L3Q65_24670	COG0647	UMP catabolic process
L3Q65_24680	COG3588	fructose-bisphosphate aldolase
L3Q65_24685	COG0583	DNA-binding transcription factor activity
L3Q65_24710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L3Q65_24745	COG2197	response regulator
L3Q65_24765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L3Q65_24815	COG1733	regulation of RNA biosynthetic process
L3Q65_24860	COG0542	response to heat
L3Q65_24875	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
L3Q65_24880	COG0443	Heat shock 70 kDa protein
L3Q65_24890	COG0477	Major facilitator Superfamily
L3Q65_24895	COG2197	response regulator
L3Q65_24900	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_24915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3Q65_24920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3Q65_24925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3Q65_24930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_24950	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_24955	COG1960	acyl-CoA dehydrogenase activity
L3Q65_24965	COG1733	regulation of RNA biosynthetic process
L3Q65_24970	COG3290	protein histidine kinase activity
L3Q65_24975	COG2204	response regulator
L3Q65_25005	COG0596	Alpha beta hydrolase
L3Q65_25015	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L3Q65_25025	COG0583	DNA-binding transcription factor activity
L3Q65_25030	COG1999	signal sequence binding
L3Q65_25045	COG0346	lactoylglutathione lyase activity
L3Q65_25095	COG4249	Peptidase C14 caspase catalytic subunit p20
L3Q65_25095	COG2319	Wd-40 repeat
L3Q65_25115	COG0477	Major facilitator Superfamily
L3Q65_25120	COG0488	(ABC) transporter
L3Q65_25145	COG2197	response regulator
L3Q65_25185	COG0444	Belongs to the ABC transporter superfamily
L3Q65_25190	COG4608	Belongs to the ABC transporter superfamily
L3Q65_25200	COG0747	negative chemotaxis
L3Q65_25205	COG1363	Peptidase, m42
L3Q65_25215	COG1136	(ABC) transporter
L3Q65_25215	COG0577	efflux transmembrane transporter activity
L3Q65_25295	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L3Q65_25330	COG2197	response regulator
L3Q65_25335	COG4585	Histidine kinase
L3Q65_25380	COG2124	cytochrome p450
L3Q65_25380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L3Q65_25385	COG1309	transcriptional regulator
L3Q65_25405	COG3842	ATPase activity
L3Q65_25420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
L3Q65_25430	COG1473	amidohydrolase
L3Q65_25445	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_25455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q65_25460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L3Q65_25465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L3Q65_25465	COG0473	3-isopropylmalate dehydrogenase activity
L3Q65_25470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L3Q65_25475	COG3384	dioxygenase
L3Q65_25480	COG2159	amidohydrolase
L3Q65_25485	COG2368	4-hydroxyphenylacetate
L3Q65_25495	COG0028	Belongs to the TPP enzyme family
L3Q65_25500	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L3Q65_25510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L3Q65_25550	COG1335	isochorismatase
L3Q65_25560	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_25570	COG1802	Transcriptional regulator
L3Q65_25585	COG0477	Major facilitator Superfamily
L3Q65_25590	COG1309	transcriptional regulator
L3Q65_25650	COG2010	Cytochrome c
L3Q65_25650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L3Q65_25670	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3Q65_25675	COG0022	dehydrogenase e1 component
L3Q65_25680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L3Q65_25710	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
L3Q65_25725	COG0251	oxidation-reduction process
L3Q65_25745	COG1309	transcriptional regulator
L3Q65_25765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_25795	COG1802	Transcriptional regulator
L3Q65_25800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q65_25805	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_25815	COG4977	sequence-specific DNA binding
L3Q65_25855	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_25905	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_25930	COG0402	S-adenosylhomocysteine deaminase activity
L3Q65_25935	COG0667	Aldo Keto reductase
L3Q65_25950	COG1595	DNA-templated transcription, initiation
L3Q65_25960	COG0640	Transcriptional regulator
L3Q65_25980	COG0477	Major facilitator Superfamily
L3Q65_26000	COG1522	sequence-specific DNA binding
L3Q65_26010	COG1584	GPR1 FUN34 yaaH family protein
L3Q65_26035	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_26040	COG3284	Transcriptional regulator
L3Q65_26060	COG1846	Transcriptional regulator
L3Q65_26065	COG0488	(ABC) transporter
L3Q65_26070	COG0488	(ABC) transporter
L3Q65_26080	COG4260	virion core protein, lumpy skin disease virus
L3Q65_26090	COG2264	protein methyltransferase activity
L3Q65_26105	COG3629	intracellular signal transduction
L3Q65_26105	COG3903	Transcriptional regulator
L3Q65_26115	COG3903	Transcriptional regulator
L3Q65_26115	COG3629	intracellular signal transduction
L3Q65_26170	COG0702	epimerase
L3Q65_26175	COG1733	regulation of RNA biosynthetic process
L3Q65_26180	COG0596	Alpha beta hydrolase
L3Q65_26185	COG1309	transcriptional regulator
L3Q65_26190	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_26230	COG4941	Belongs to the sigma-70 factor family
L3Q65_26245	COG3173	Aminoglycoside phosphotransferase
L3Q65_26250	COG1234	tRNA 3'-trailer cleavage
L3Q65_26255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3Q65_26270	COG1309	transcriptional regulator
L3Q65_26295	COG0604	alcohol dehydrogenase
L3Q65_26295	COG3321	synthase
L3Q65_26305	COG0604	alcohol dehydrogenase
L3Q65_26305	COG3321	synthase
L3Q65_26320	COG0577	efflux transmembrane transporter activity
L3Q65_26320	COG1136	(ABC) transporter
L3Q65_26340	COG3321	synthase
L3Q65_26340	COG0604	alcohol dehydrogenase
L3Q65_26340	COG3321	synthase
L3Q65_26340	COG0604	alcohol dehydrogenase
L3Q65_26345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3Q65_26405	COG0604	alcohol dehydrogenase
L3Q65_26405	COG3321	synthase
L3Q65_26435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_26450	COG2267	carboxylic ester hydrolase activity
L3Q65_26465	COG2197	response regulator
L3Q65_26475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3Q65_26505	COG1522	sequence-specific DNA binding
L3Q65_26540	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L3Q65_26545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3Q65_26550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_26570	COG2226	methyltransferase
L3Q65_26575	COG2226	methyltransferase
L3Q65_26595	COG1595	DNA-templated transcription, initiation
L3Q65_26635	COG0242	peptide deformylase activity
L3Q65_26650	COG1309	transcriptional regulator
L3Q65_26720	COG2226	methyltransferase
L3Q65_26735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L3Q65_26770	COG1940	carbohydrate kinase activity
L3Q65_26775	COG0747	negative chemotaxis
L3Q65_26780	COG0601	transmembrane transport
L3Q65_26785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_26790	COG4172	Belongs to the ABC transporter superfamily
L3Q65_26810	COG3511	phospholipase C
L3Q65_26815	COG2837	iron assimilation
L3Q65_26820	COG2822	iron ion transport
L3Q65_26835	COG1929	Belongs to the glycerate kinase type-1 family
L3Q65_26845	COG2252	PERMEase
L3Q65_26850	COG0590	tRNA wobble adenosine to inosine editing
L3Q65_26860	COG3835	regulator
L3Q65_26880	COG1228	amidohydrolase
L3Q65_26905	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_26920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L3Q65_26930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_26965	COG1280	lysine exporter protein (LysE YggA)
L3Q65_26980	COG1408	metallophosphoesterase
L3Q65_26990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q65_26995	COG2801	Transposase and inactivated derivatives
L3Q65_27025	COG2018	Roadblock/LC7 domain
L3Q65_27030	COG0642	Histidine kinase
L3Q65_27040	COG3844	kynureninase activity
L3Q65_27050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3Q65_27075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L3Q65_27080	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_27100	COG1316	TRANSCRIPTIONal
L3Q65_27140	COG0789	Transcriptional regulator
L3Q65_27165	COG1309	transcriptional regulator
L3Q65_27175	COG0583	DNA-binding transcription factor activity
L3Q65_27205	COG2205	protein histidine kinase activity
L3Q65_27210	COG0745	RESPONSE REGULATOR receiver
L3Q65_27215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
L3Q65_27220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
L3Q65_27230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L3Q65_27285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L3Q65_27290	COG1335	isochorismatase
L3Q65_27300	COG1268	BioY protein
L3Q65_27330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L3Q65_27340	COG2267	carboxylic ester hydrolase activity
L3Q65_27350	COG0477	Major facilitator Superfamily
L3Q65_27375	COG0626	cystathionine gamma-synthase activity
L3Q65_27395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3Q65_27400	COG1461	Dihydroxyacetone kinase
L3Q65_27405	COG2376	Dihydroxyacetone kinase
L3Q65_27440	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
L3Q65_27450	COG1024	Enoyl-CoA hydratase
L3Q65_27455	COG4977	sequence-specific DNA binding
L3Q65_27465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
L3Q65_27465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
L3Q65_27485	COG1280	lysine exporter protein (LysE YggA)
L3Q65_27495	COG0702	epimerase
L3Q65_27500	COG3631	Ketosteroid isomerase-related protein
L3Q65_27545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
L3Q65_27550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
L3Q65_27555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
L3Q65_27560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
L3Q65_27570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
L3Q65_27575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
L3Q65_27580	COG0356	it plays a direct role in the translocation of protons across the membrane
L3Q65_27590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L3Q65_27610	COG2890	protein-(glutamine-N5) methyltransferase activity
L3Q65_27615	COG0789	Transcriptional regulator
L3Q65_27625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_27630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
L3Q65_27635	COG0254	rRNA binding
L3Q65_27645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L3Q65_27650	COG0083	homoserine kinase activity
L3Q65_27655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L3Q65_27660	COG0460	homoserine dehydrogenase
L3Q65_27665	COG0019	diaminopimelate decarboxylase activity
L3Q65_27670	COG0018	arginyl-trna synthetase
L3Q65_27685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q65_27695	COG0596	Alpha beta hydrolase
L3Q65_27710	COG2197	response regulator
L3Q65_27715	COG4585	Histidine kinase
L3Q65_27775	COG2226	methyltransferase
L3Q65_27785	COG3903	Transcriptional regulator
L3Q65_27785	COG3629	intracellular signal transduction
L3Q65_27815	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_27820	COG0604	alcohol dehydrogenase
L3Q65_27820	COG3321	synthase
L3Q65_27820	COG3321	synthase
L3Q65_27820	COG0604	alcohol dehydrogenase
L3Q65_27830	COG3903	Transcriptional regulator
L3Q65_27830	COG3629	intracellular signal transduction
L3Q65_27850	COG2124	cytochrome p450
L3Q65_27855	COG0604	alcohol dehydrogenase
L3Q65_27855	COG3321	synthase
L3Q65_27865	COG3321	synthase
L3Q65_27865	COG0604	alcohol dehydrogenase
L3Q65_27875	COG0604	alcohol dehydrogenase
L3Q65_27875	COG3321	synthase
L3Q65_27885	COG3321	synthase
L3Q65_27885	COG0604	alcohol dehydrogenase
L3Q65_27910	COG3629	intracellular signal transduction
L3Q65_27910	COG3903	Transcriptional regulator
L3Q65_27915	COG0596	Alpha beta hydrolase
L3Q65_27920	COG2197	response regulator
L3Q65_27925	COG4585	Histidine kinase
L3Q65_27935	COG0402	S-adenosylhomocysteine deaminase activity
L3Q65_27945	COG1414	Transcriptional regulator
L3Q65_27975	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_27985	COG0477	Major facilitator Superfamily
L3Q65_27990	COG0277	FAD linked oxidase domain protein
L3Q65_28005	COG0667	Aldo Keto reductase
L3Q65_28010	COG1619	proteins homologs of microcin C7 resistance protein MccF
L3Q65_28020	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
L3Q65_28040	COG3226	Transcriptional regulator
L3Q65_28065	COG0583	DNA-binding transcription factor activity
L3Q65_28075	COG2132	Multicopper oxidase
L3Q65_28095	COG0745	RESPONSE REGULATOR receiver
L3Q65_28100	COG2205	protein histidine kinase activity
L3Q65_28115	COG0577	efflux transmembrane transporter activity
L3Q65_28115	COG1136	(ABC) transporter
L3Q65_28120	COG0577	efflux transmembrane transporter activity
L3Q65_28120	COG1136	(ABC) transporter
L3Q65_28125	COG2197	response regulator
L3Q65_28135	COG1309	transcriptional regulator
L3Q65_28165	COG2072	flavoprotein involved in K transport
L3Q65_28175	COG1595	DNA-templated transcription, initiation
L3Q65_28180	COG1252	NADH dehydrogenase
L3Q65_28185	COG0454	-acetyltransferase
L3Q65_28190	COG0488	(ABC) transporter
L3Q65_28200	COG0477	Major facilitator Superfamily
L3Q65_28210	COG2226	methyltransferase
L3Q65_28215	COG1476	TRANSCRIPTIONal
L3Q65_28235	COG0159	tryptophan synthase activity
L3Q65_28240	COG2188	Transcriptional regulator
L3Q65_28255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L3Q65_28265	COG2197	response regulator
L3Q65_28270	COG4585	Histidine kinase
L3Q65_28300	COG0277	FAD linked oxidase domain protein
L3Q65_28315	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_28320	COG3835	regulator
L3Q65_28330	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_28335	COG0583	DNA-binding transcription factor activity
L3Q65_28365	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_28465	COG0477	Major facilitator Superfamily
L3Q65_28470	COG1802	Transcriptional regulator
L3Q65_28520	COG0154	amidase activity
L3Q65_28540	COG2186	Transcriptional regulator
L3Q65_28555	COG0473	3-isopropylmalate dehydrogenase activity
L3Q65_28565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L3Q65_28580	COG0028	Belongs to the TPP enzyme family
L3Q65_28605	COG1024	Enoyl-CoA hydratase
L3Q65_28605	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_28610	COG0183	Belongs to the thiolase family
L3Q65_28615	COG1309	transcriptional regulator
L3Q65_28630	COG1960	acyl-CoA dehydrogenase activity
L3Q65_28640	COG1733	regulation of RNA biosynthetic process
L3Q65_28645	COG4221	oxidoreductase activity
L3Q65_28645	COG3321	synthase
L3Q65_28645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q65_28645	COG0604	alcohol dehydrogenase
L3Q65_28665	COG3243	poly(R)-hydroxyalkanoic acid synthase
L3Q65_28670	COG4221	oxidoreductase activity
L3Q65_28680	COG1960	acyl-CoA dehydrogenase activity
L3Q65_28690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3Q65_28705	COG2755	lipolytic protein G-D-S-L family
L3Q65_28710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L3Q65_28740	COG0686	Belongs to the AlaDH PNT family
L3Q65_28745	COG1132	(ABC) transporter
L3Q65_28775	COG3321	synthase
L3Q65_28775	COG0604	alcohol dehydrogenase
L3Q65_28780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3Q65_28785	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
L3Q65_28795	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_28820	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_28830	COG0477	Major facilitator Superfamily
L3Q65_28835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3Q65_28840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3Q65_28850	COG3629	intracellular signal transduction
L3Q65_28850	COG3903	Transcriptional regulator
L3Q65_28855	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_28875	COG0567	Dehydrogenase, E1 component
L3Q65_28875	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3Q65_28910	COG1174	glycine betaine transport
L3Q65_28915	COG1174	glycine betaine transport
L3Q65_28920	COG1125	glycine betaine transport
L3Q65_28920	COG0517	IMP dehydrogenase activity
L3Q65_28940	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
L3Q65_28955	COG0406	alpha-ribazole phosphatase activity
L3Q65_28965	COG0596	Alpha beta hydrolase
L3Q65_28975	COG1597	lipid kinase activity
L3Q65_29000	COG1595	DNA-templated transcription, initiation
L3Q65_29005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L3Q65_29010	COG2226	methyltransferase
L3Q65_29025	COG2197	response regulator
L3Q65_29035	COG2135	peptidase activity
L3Q65_29040	COG1162	GTPase activity
L3Q65_29070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3Q65_29075	COG1011	Hydrolase
L3Q65_29085	COG0653	protein targeting
L3Q65_29090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
L3Q65_29100	COG5401	PFAM Sporulation and spore germination
L3Q65_29105	COG5002	protein histidine kinase activity
L3Q65_29110	COG0745	RESPONSE REGULATOR receiver
L3Q65_29135	COG1309	transcriptional regulator
L3Q65_29155	COG1309	transcriptional regulator
L3Q65_29165	COG0442	prolyl-tRNA aminoacylation
L3Q65_29175	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L3Q65_29190	COG0531	amino acid
L3Q65_29200	COG1482	cell wall glycoprotein biosynthetic process
L3Q65_29210	COG2835	tetraacyldisaccharide 4'-kinase activity
L3Q65_29240	COG1994	Peptidase M50
L3Q65_29255	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3Q65_29265	COG0601	transmembrane transport
L3Q65_29280	COG4608	Belongs to the ABC transporter superfamily
L3Q65_29285	COG0747	negative chemotaxis
L3Q65_29290	COG1217	gtp-binding protein TYPA
L3Q65_29305	COG0180	Tryptophanyl-tRNA synthetase
L3Q65_29315	COG0494	nUDIX hydrolase
L3Q65_29315	COG0406	alpha-ribazole phosphatase activity
L3Q65_29320	COG2205	protein histidine kinase activity
L3Q65_29325	COG0745	RESPONSE REGULATOR receiver
L3Q65_29335	COG1131	(ABC) transporter
L3Q65_29345	COG3842	ATPase activity
L3Q65_29360	COG2154	pterin-4-alpha-carbinolamine dehydratase
L3Q65_29380	COG0012	GTP binding
L3Q65_29395	COG0419	ATPase involved in DNA repair
L3Q65_29400	COG0420	3'-5' exonuclease activity
L3Q65_29415	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
L3Q65_29425	COG1570	exodeoxyribonuclease VII activity
L3Q65_29440	COG1722	exodeoxyribonuclease VII activity
L3Q65_29455	COG0492	ferredoxin-NADP+ reductase activity
L3Q65_29460	COG0114	fumarate hydratase activity
L3Q65_29470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_29480	COG1793	dna ligase
L3Q65_29515	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L3Q65_29545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L3Q65_29560	COG1331	Highly conserved protein containing a thioredoxin domain
L3Q65_29595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3Q65_29605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L3Q65_29610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q65_29615	COG1522	sequence-specific DNA binding
L3Q65_29620	COG3185	4-Hydroxyphenylpyruvate dioxygenase
L3Q65_29655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L3Q65_29695	COG0183	Belongs to the thiolase family
L3Q65_29700	COG0477	Major facilitator Superfamily
L3Q65_29780	COG1175	transmembrane transport
L3Q65_29790	COG2197	response regulator
L3Q65_29795	COG1472	Belongs to the glycosyl hydrolase 3 family
L3Q65_29820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_29825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L3Q65_29835	COG0443	Heat shock 70 kDa protein
L3Q65_29865	COG0395	ABC-type sugar transport system, permease component
L3Q65_29895	COG1876	peptidase activity
L3Q65_29915	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_29920	COG3268	Saccharopine dehydrogenase
L3Q65_29925	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_29930	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_29940	COG0671	phosphoesterase, PA-phosphatase related
L3Q65_29955	COG0501	Belongs to the peptidase M48B family
L3Q65_29970	COG1316	TRANSCRIPTIONal
L3Q65_29985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L3Q65_29995	COG1414	Transcriptional regulator
L3Q65_30000	COG3591	Belongs to the peptidase S1B family
L3Q65_30005	COG0154	amidase activity
L3Q65_30075	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L3Q65_30075	COG2508	Transcriptional regulator
L3Q65_30080	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_30095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
L3Q65_30105	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
L3Q65_30110	COG2271	Major facilitator Superfamily
L3Q65_30135	COG3239	Fatty acid desaturase
L3Q65_30165	COG1132	(ABC) transporter
L3Q65_30185	COG2161	toxin-antitoxin pair type II binding
L3Q65_30200	COG1252	NADH dehydrogenase
L3Q65_30215	COG2197	response regulator
L3Q65_30225	COG1131	(ABC) transporter
L3Q65_30250	COG4608	Belongs to the ABC transporter superfamily
L3Q65_30265	COG0601	transmembrane transport
L3Q65_30280	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_30285	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_30290	COG0583	DNA-binding transcription factor activity
L3Q65_30315	COG0148	phosphopyruvate hydratase activity
L3Q65_30340	COG0672	)-iron permease
L3Q65_30350	COG2837	iron assimilation
L3Q65_30355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_30375	COG1131	(ABC) transporter
L3Q65_30385	COG1595	DNA-templated transcription, initiation
L3Q65_30390	COG3956	TIGRFAM MazG family protein
L3Q65_30410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_30420	COG0586	Pfam SNARE associated Golgi protein
L3Q65_30430	COG4585	Histidine kinase
L3Q65_30435	COG2197	response regulator
L3Q65_30440	COG2133	pyrroloquinoline quinone binding
L3Q65_30445	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_30455	COG0494	nUDIX hydrolase
L3Q65_30485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
L3Q65_30510	COG1309	transcriptional regulator
L3Q65_30535	COG0193	aminoacyl-tRNA hydrolase activity
L3Q65_30545	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_30555	COG0488	(ABC) transporter
L3Q65_30560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
L3Q65_30570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L3Q65_30575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L3Q65_30585	COG0084	hydrolase, TatD family'
L3Q65_30590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3Q65_30645	COG0515	serine threonine protein kinase
L3Q65_30660	COG2258	MOSC domain
L3Q65_30685	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_30715	COG4585	Histidine kinase
L3Q65_30720	COG2197	response regulator
L3Q65_30745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L3Q65_30750	COG2197	response regulator
L3Q65_30770	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_30780	COG0583	DNA-binding transcription factor activity
L3Q65_30900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3Q65_30910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L3Q65_30915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L3Q65_30940	COG0315	cyclic pyranopterin monophosphate synthase activity
L3Q65_30940	COG0521	Mo-molybdopterin cofactor biosynthetic process
L3Q65_30950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
L3Q65_30955	COG5002	protein histidine kinase activity
L3Q65_30960	COG0745	RESPONSE REGULATOR receiver
L3Q65_30995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3Q65_31005	COG1349	DNA-binding transcription factor activity
L3Q65_31020	COG2860	membrane
L3Q65_31025	COG2197	response regulator
L3Q65_31045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_31065	COG1309	transcriptional regulator
L3Q65_31075	COG0702	epimerase
L3Q65_31180	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_31190	COG1960	acyl-CoA dehydrogenase activity
L3Q65_31200	COG0583	DNA-binding transcription factor activity
L3Q65_31205	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L3Q65_31260	COG1793	dna ligase
L3Q65_31260	COG3285	dna ligase
L3Q65_31275	COG0583	DNA-binding transcription factor activity
L3Q65_31315	COG1960	acyl-CoA dehydrogenase activity
L3Q65_31335	COG2814	Major facilitator Superfamily
L3Q65_31340	COG4336	lyase activity
L3Q65_31345	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
L3Q65_31355	COG1984	allophanate hydrolase subunit 2
L3Q65_31380	COG1321	iron dependent repressor
L3Q65_31395	COG1024	Enoyl-CoA hydratase
L3Q65_31400	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_31420	COG1169	isochorismate synthase
L3Q65_31435	COG2182	Extracellular solute-binding protein
L3Q65_31440	COG1175	transmembrane transport
L3Q65_31445	COG0395	ABC-type sugar transport system, permease component
L3Q65_31470	COG2318	DinB family
L3Q65_31485	COG2226	methyltransferase
L3Q65_31490	COG0277	FAD linked oxidase domain protein
L3Q65_31515	COG4152	abc transporter atp-binding protein
L3Q65_31520	COG1668	transmembrane transport
L3Q65_31545	COG1960	acyl-CoA dehydrogenase activity
L3Q65_31550	COG1733	regulation of RNA biosynthetic process
L3Q65_31555	COG0702	epimerase
L3Q65_31565	COG1228	amidohydrolase
L3Q65_31580	COG1309	transcriptional regulator
L3Q65_31595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L3Q65_31600	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_31610	COG1113	amino acid transport
L3Q65_31615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L3Q65_31620	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
L3Q65_31625	COG0028	Belongs to the TPP enzyme family
L3Q65_31645	COG0259	pyridoxamine-phosphate oxidase activity
L3Q65_31655	COG0829	nickel cation binding
L3Q65_31660	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
L3Q65_31670	COG0804	urea catabolic process
L3Q65_31675	COG0832	Belongs to the urease beta subunit family
L3Q65_31680	COG0831	urea catabolic process
L3Q65_31715	COG4585	Histidine kinase
L3Q65_31720	COG2197	response regulator
L3Q65_31755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3Q65_31770	COG5398	heme oxygenase
L3Q65_31785	COG2814	Major facilitator Superfamily
L3Q65_31795	COG2252	PERMEase
L3Q65_31820	COG2814	Major facilitator Superfamily
L3Q65_31830	COG1278	Cold shock
L3Q65_31845	COG1309	transcriptional regulator
L3Q65_31850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3Q65_31855	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_31870	COG3304	Inner membrane component domain
L3Q65_31885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L3Q65_31920	COG1846	Transcriptional regulator
L3Q65_31970	COG2018	Roadblock/LC7 domain
L3Q65_31985	COG2018	Roadblock/LC7 domain
L3Q65_31995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L3Q65_32005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3Q65_32010	COG1116	anion transmembrane transporter activity
L3Q65_32030	COG3142	Participates in the control of copper homeostasis
L3Q65_32050	COG1061	Type III restriction enzyme res subunit
L3Q65_32055	COG2197	response regulator
L3Q65_32060	COG4585	Histidine kinase
L3Q65_32065	COG0586	Pfam SNARE associated Golgi protein
L3Q65_32085	COG3903	Transcriptional regulator
L3Q65_32085	COG2319	Wd-40 repeat
L3Q65_32090	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_32100	COG0459	protein refolding
L3Q65_32110	COG1278	Cold shock
L3Q65_32135	COG2261	transglycosylase associated protein
L3Q65_32140	COG0688	phosphatidylethanolamine metabolic process
L3Q65_32160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3Q65_32175	COG0242	peptide deformylase activity
L3Q65_32180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
L3Q65_32185	COG0351	phosphomethylpyrimidine kinase
L3Q65_32220	COG2022	thiamine diphosphate biosynthetic process
L3Q65_32230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q65_32230	COG2022	thiamine diphosphate biosynthetic process
L3Q65_32235	COG0352	thiamine-phosphate diphosphorylase activity
L3Q65_32245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L3Q65_32260	COG0477	Major facilitator Superfamily
L3Q65_32265	COG2188	Transcriptional regulator
L3Q65_32270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L3Q65_32285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L3Q65_32315	COG3903	Transcriptional regulator
L3Q65_32315	COG3629	intracellular signal transduction
L3Q65_32320	COG5285	phytanoyl-CoA dioxygenase
L3Q65_32325	COG1917	Cupin 2, conserved barrel domain protein
L3Q65_32335	COG0456	acetyltransferase
L3Q65_32340	COG1752	Esterase of the alpha-beta hydrolase superfamily
L3Q65_32345	COG4399	Belongs to the UPF0754 family
L3Q65_32360	COG5416	Lipopolysaccharide assembly protein A domain
L3Q65_32370	COG0400	carboxylic ester hydrolase activity
L3Q65_32430	COG3971	2-oxopent-4-enoate hydratase activity
L3Q65_32435	COG0346	lactoylglutathione lyase activity
L3Q65_32445	COG1832	CoA-binding protein
L3Q65_32460	COG0745	RESPONSE REGULATOR receiver
L3Q65_32465	COG2205	protein histidine kinase activity
L3Q65_32470	COG1492	cobalamin metabolic process
L3Q65_32475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
L3Q65_32480	COG1414	Transcriptional regulator
L3Q65_32485	COG4941	Belongs to the sigma-70 factor family
L3Q65_32495	COG3795	YCII-related domain
L3Q65_32515	COG0596	Alpha beta hydrolase
L3Q65_32520	COG1946	Acyl-CoA thioesterase
L3Q65_32545	COG4566	intracellular signal transduction
L3Q65_32550	COG0154	amidase activity
L3Q65_32565	COG3852	Histidine kinase
L3Q65_32580	COG4638	Rieske (2fe-2S)
L3Q65_32600	COG0477	Major facilitator Superfamily
L3Q65_32635	COG1309	transcriptional regulator
L3Q65_32685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L3Q65_32695	COG1329	Transcriptional regulator
L3Q65_32700	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
L3Q65_32705	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
L3Q65_32725	COG0215	cysteine-tRNA ligase activity
L3Q65_32765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L3Q65_32770	COG0698	ribose 5-phosphate isomerase
L3Q65_32775	COG2376	Dihydroxyacetone kinase
L3Q65_32780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q65_32790	COG1349	DNA-binding transcription factor activity
L3Q65_32795	COG2814	Major facilitator Superfamily
L3Q65_32800	COG1070	Carbohydrate kinase
L3Q65_32805	COG2814	Major facilitator Superfamily
L3Q65_32830	COG4399	Belongs to the UPF0754 family
L3Q65_32840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L3Q65_32845	COG1120	ATPase activity
L3Q65_32850	COG0803	Belongs to the bacterial solute-binding protein 9 family
L3Q65_32855	COG1609	Transcriptional regulator
L3Q65_32865	COG1194	a g-specific adenine glycosylase
L3Q65_32885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3Q65_32940	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
L3Q65_32945	COG0443	Heat shock 70 kDa protein
L3Q65_32980	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
L3Q65_32990	COG2076	Multidrug Resistance protein
L3Q65_32995	COG1595	DNA-templated transcription, initiation
L3Q65_33005	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
L3Q65_33010	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
L3Q65_33015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
L3Q65_33040	COG0789	Transcriptional regulator
L3Q65_33060	COG0302	gtp cyclohydrolase
L3Q65_33065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3Q65_33095	COG0037	tRNA processing
L3Q65_33105	COG2027	D-alanyl-D-alanine carboxypeptidase
L3Q65_33110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L3Q65_33120	COG3795	YCII-related domain
L3Q65_33125	COG4941	Belongs to the sigma-70 factor family
L3Q65_33130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
L3Q65_33155	COG0640	Transcriptional regulator
L3Q65_33170	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_33200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L3Q65_33205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
L3Q65_33220	COG2223	nitrite transmembrane transporter activity
L3Q65_33225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L3Q65_33225	COG1754	DNA topoisomerase type I activity
L3Q65_33255	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
L3Q65_33260	COG1111	helicase
L3Q65_33260	COG1205	dead DEAH box helicase
L3Q65_33310	COG1472	Belongs to the glycosyl hydrolase 3 family
L3Q65_33315	COG3876	Protein conserved in bacteria
L3Q65_33320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3Q65_33325	COG1737	Transcriptional regulator
L3Q65_33330	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
L3Q65_33335	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
L3Q65_33345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3Q65_33350	COG1595	DNA-templated transcription, initiation
L3Q65_33355	COG0667	Aldo Keto reductase
L3Q65_33375	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_33385	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
L3Q65_33395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q65_33410	COG3104	oligopeptide transport
L3Q65_33415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L3Q65_33425	COG0596	Alpha beta hydrolase
L3Q65_33480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q65_33530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3Q65_33540	COG1408	metallophosphoesterase
L3Q65_33565	COG0076	glutamate decarboxylase activity
L3Q65_33570	COG0783	Belongs to the Dps family
L3Q65_33575	COG1764	response to oxidative stress
L3Q65_33580	COG0431	NADPH-dependent FMN reductase
L3Q65_33585	COG0657	acetylesterase activity
L3Q65_33605	COG1690	Belongs to the RtcB family
L3Q65_33650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L3Q65_33660	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_33680	COG0583	DNA-binding transcription factor activity
L3Q65_33685	COG0697	spore germination
L3Q65_33700	COG4941	Belongs to the sigma-70 factor family
L3Q65_33705	COG3795	YCII-related domain
L3Q65_33715	COG4608	Belongs to the ABC transporter superfamily
L3Q65_33720	COG0444	Belongs to the ABC transporter superfamily
L3Q65_33725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_33730	COG0601	transmembrane transport
L3Q65_33735	COG0747	negative chemotaxis
L3Q65_33750	COG1216	Glycosyl transferase, family 2
L3Q65_33765	COG1215	transferase activity, transferring glycosyl groups
L3Q65_33770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L3Q65_33790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L3Q65_33795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
L3Q65_33800	COG0860	N-Acetylmuramoyl-L-alanine amidase
L3Q65_33845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
L3Q65_33850	COG2205	protein histidine kinase activity
L3Q65_33855	COG0745	RESPONSE REGULATOR receiver
L3Q65_33880	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_33890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L3Q65_33955	COG1674	ftsk spoiiie
L3Q65_33970	COG2843	Capsule synthesis protein
L3Q65_33985	COG2175	clavaminate synthase activity
L3Q65_34000	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L3Q65_34025	COG1473	amidohydrolase
L3Q65_34030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q65_34100	COG0596	Alpha beta hydrolase
L3Q65_34105	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
L3Q65_34125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L3Q65_34150	COG0745	RESPONSE REGULATOR receiver
L3Q65_34185	COG4044	May play a role in the intracellular transport of hydrophobic ligands
L3Q65_34190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
L3Q65_34195	COG1984	allophanate hydrolase subunit 2
L3Q65_34210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
L3Q65_34250	COG3845	ABC transporter
L3Q65_34345	COG1132	(ABC) transporter
L3Q65_34350	COG1132	(ABC) transporter
L3Q65_34370	COG0047	phosphoribosylformylglycinamidine synthase activity
L3Q65_34375	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L3Q65_34425	COG2226	methyltransferase
L3Q65_34445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
L3Q65_34460	COG1126	abc transporter atp-binding protein
L3Q65_34465	COG0765	amino acid transport
L3Q65_34470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q65_34480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L3Q65_34485	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_34495	COG0800	Aldolase
L3Q65_34545	COG1011	Hydrolase
L3Q65_34565	COG0436	Aminotransferase
L3Q65_34570	COG3953	SLT domain
L3Q65_34570	COG5280	Phage tail tape measure protein TP901
L3Q65_34605	COG0584	glycerophosphoryl diester phosphodiesterase
L3Q65_34625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_34640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L3Q65_34675	COG2153	protein acetylation
L3Q65_34730	COG0667	Aldo Keto reductase
L3Q65_34735	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_34790	COG0586	Pfam SNARE associated Golgi protein
L3Q65_34795	COG0277	FAD linked oxidase domain protein
L3Q65_34810	COG1309	transcriptional regulator
L3Q65_34815	COG0477	Major facilitator Superfamily
L3Q65_34825	COG3467	pyridoxamine 5'-phosphate
L3Q65_34845	COG0586	Pfam SNARE associated Golgi protein
L3Q65_34855	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_34865	COG0572	uridine kinase
L3Q65_34870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L3Q65_34890	COG1609	Transcriptional regulator
L3Q65_34910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3Q65_34935	COG1595	DNA-templated transcription, initiation
L3Q65_34950	COG1136	(ABC) transporter
L3Q65_34955	COG0300	oxidoreductase activity
L3Q65_34985	COG0542	response to heat
L3Q65_35010	COG0412	Dienelactone hydrolase
L3Q65_35020	COG4585	Histidine kinase
L3Q65_35025	COG2197	response regulator
L3Q65_35040	COG0789	Transcriptional regulator
L3Q65_35045	COG0484	heat shock protein binding
L3Q65_35050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
L3Q65_35055	COG0443	Heat shock 70 kDa protein
L3Q65_35080	COG2816	NAD+ diphosphatase activity
L3Q65_35095	COG2076	Multidrug Resistance protein
L3Q65_35100	COG0247	lactate metabolic process
L3Q65_35100	COG2181	nitrate reductase activity
L3Q65_35115	COG2340	Cysteine-rich secretory protein family
L3Q65_35120	COG3848	Pyruvate phosphate dikinase
L3Q65_35120	COG0574	Belongs to the PEP-utilizing enzyme family
L3Q65_35140	COG0717	Belongs to the dCTP deaminase family
L3Q65_35190	COG1960	acyl-CoA dehydrogenase activity
L3Q65_35195	COG2197	response regulator
L3Q65_35215	COG1525	nuclease
L3Q65_35215	COG0737	Belongs to the 5'-nucleotidase family
L3Q65_35215	COG4085	toxin activity
L3Q65_35225	COG2720	vancomycin resistance protein
L3Q65_35230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
L3Q65_35285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q65_35300	COG1305	Transglutaminase-like
L3Q65_35305	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3Q65_35310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3Q65_35320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3Q65_35330	COG0022	dehydrogenase e1 component
L3Q65_35335	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3Q65_35350	COG4133	protoheme IX ABC transporter activity
L3Q65_35370	COG3030	protein affecting phage T7 exclusion by the F plasmid
L3Q65_35430	COG1309	transcriptional regulator
L3Q65_35435	COG2030	dehydratase
L3Q65_35440	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_35445	COG0183	Belongs to the thiolase family
L3Q65_35470	COG0456	acetyltransferase
L3Q65_35505	COG0583	DNA-binding transcription factor activity
L3Q65_35525	COG1131	(ABC) transporter
L3Q65_35535	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
L3Q65_35555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
L3Q65_35580	COG4585	Histidine kinase
L3Q65_35585	COG2197	response regulator
L3Q65_35600	COG1131	(ABC) transporter
L3Q65_35615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L3Q65_35625	COG1136	(ABC) transporter
L3Q65_35635	COG2197	response regulator
L3Q65_35640	COG0402	S-adenosylhomocysteine deaminase activity
L3Q65_35645	COG4221	oxidoreductase activity
L3Q65_35650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
L3Q65_35665	COG2814	Major facilitator Superfamily
L3Q65_35675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q65_35680	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L3Q65_35690	COG1695	Transcriptional regulator
L3Q65_35700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3Q65_35705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3Q65_35710	COG0673	inositol 2-dehydrogenase activity
L3Q65_35715	COG1940	carbohydrate kinase activity
L3Q65_35745	COG0360	Binds together with S18 to 16S ribosomal RNA
L3Q65_35755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
L3Q65_35760	COG0359	binds to the 23S rRNA
L3Q65_35800	COG3384	dioxygenase
L3Q65_35825	COG2197	response regulator
L3Q65_35840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L3Q65_35850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L3Q65_35860	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_35880	COG0495	leucyl-tRNA aminoacylation
L3Q65_35895	COG1678	Uncharacterized ACR, COG1678
L3Q65_35930	COG4585	Histidine kinase
L3Q65_35935	COG0617	tRNA 3'-terminal CCA addition
L3Q65_35960	COG1595	DNA-templated transcription, initiation
L3Q65_35975	COG0492	ferredoxin-NADP+ reductase activity
L3Q65_35975	COG3118	belongs to the thioredoxin family
L3Q65_35980	COG0860	N-Acetylmuramoyl-L-alanine amidase
L3Q65_35980	COG3409	Peptidoglycan-binding domain 1 protein
L3Q65_35995	COG1181	Belongs to the D-alanine--D-alanine ligase family
L3Q65_36005	COG1192	Involved in chromosome partitioning
L3Q65_36010	COG0357	Ribosomal RNA small subunit methyltransferase G
L3Q65_36030	COG0706	membrane insertase activity
L3Q65_36035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
L3Q65_36040	COG0594	ribonuclease P activity
L3Q65_36055	COG0592	DNA-directed DNA polymerase activity
L3Q65_36060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L3Q65_36065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L3Q65_36070	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
L3Q65_36075	COG0187	DNA topoisomerase II activity
L3Q65_36080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L3Q65_36150	COG3973	AAA domain
L3Q65_36155	COG5650	phosphatidylinositol metabolic process
L3Q65_36170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L3Q65_36215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L3Q65_36235	COG3764	Sortase (surface protein transpeptidase)
L3Q65_36290	COG2815	serine threonine protein kinase
L3Q65_36290	COG0515	serine threonine protein kinase
L3Q65_36295	COG0515	serine threonine protein kinase
L3Q65_36300	COG0768	penicillin binding
L3Q65_36315	COG1716	ATPase activity
L3Q65_36320	COG1716	ATPase activity
L3Q65_36375	COG0583	DNA-binding transcription factor activity
L3Q65_36395	COG2186	Transcriptional regulator
L3Q65_36400	COG0747	negative chemotaxis
L3Q65_36410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3Q65_36415	COG0444	Belongs to the ABC transporter superfamily
L3Q65_36420	COG4608	Belongs to the ABC transporter superfamily
L3Q65_36425	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_36435	COG0154	amidase activity
L3Q65_36440	COG2301	Belongs to the HpcH HpaI aldolase family
L3Q65_36445	COG2301	Belongs to the HpcH HpaI aldolase family
L3Q65_36455	COG0702	epimerase
L3Q65_36460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L3Q65_36485	COG2211	Major facilitator Superfamily
L3Q65_36490	COG0789	Transcriptional regulator
L3Q65_36495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3Q65_36500	COG3209	COG3209 Rhs family protein
L3Q65_36530	COG2372	response to copper ion
L3Q65_36530	COG1276	copper resistance
L3Q65_36545	COG1174	glycine betaine transport
L3Q65_36555	COG1174	glycine betaine transport
L3Q65_36585	COG2226	methyltransferase
L3Q65_36595	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L3Q65_36620	COG0477	Major facilitator Superfamily
L3Q65_36640	COG4585	Histidine kinase
L3Q65_36645	COG2197	response regulator
L3Q65_36660	COG0438	transferase activity, transferring glycosyl groups
L3Q65_36710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L3Q65_36715	COG3275	phosphorelay sensor kinase activity
L3Q65_36725	COG3279	Response regulator of the LytR AlgR family
L3Q65_36735	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q65_36760	COG2814	Major facilitator Superfamily
L3Q65_36765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3Q65_36785	COG1191	sigma factor activity
L3Q65_36850	COG1271	oxidase subunit
L3Q65_36855	COG1294	oxidase, subunit
L3Q65_36860	COG4988	ABC transporter
L3Q65_36870	COG0596	Alpha beta hydrolase
L3Q65_36920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
L3Q65_36930	COG0588	phosphoglycerate mutase activity
L3Q65_36965	COG0754	glutathionylspermidine amidase activity
L3Q65_36975	COG0596	Alpha beta hydrolase
L3Q65_36980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3Q65_36985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
L3Q65_37000	COG0579	oxidoreductase
L3Q65_37010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3Q65_37025	COG0110	maltose O-acetyltransferase activity
L3Q65_37050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3Q65_37055	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L3Q65_37065	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_37070	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_37110	COG0561	phosphatase activity
L3Q65_37115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_37130	COG0671	phosphoesterase, PA-phosphatase related
L3Q65_37135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L3Q65_37145	COG4221	oxidoreductase activity
L3Q65_37170	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_37175	COG0277	FAD linked oxidase domain protein
L3Q65_37185	COG1216	Glycosyl transferase, family 2
L3Q65_37220	COG1216	Glycosyl transferase, family 2
L3Q65_37250	COG2089	acid synthase
L3Q65_37265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3Q65_37270	COG1086	Polysaccharide biosynthesis protein
L3Q65_37275	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
L3Q65_37290	COG0596	Alpha beta hydrolase
L3Q65_37305	COG1063	alcohol dehydrogenase
L3Q65_37325	COG4249	Peptidase C14 caspase catalytic subunit p20
L3Q65_37365	COG4565	transcriptional regulatory protein
L3Q65_37370	COG3290	protein histidine kinase activity
L3Q65_37375	COG1116	anion transmembrane transporter activity
L3Q65_37395	COG2329	Antibiotic biosynthesis monooxygenase
L3Q65_37405	COG2197	response regulator
L3Q65_37420	COG1522	sequence-specific DNA binding
L3Q65_37425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3Q65_37455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L3Q65_37460	COG2186	Transcriptional regulator
L3Q65_37485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
L3Q65_37495	COG0604	alcohol dehydrogenase
L3Q65_37505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q65_37510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L3Q65_37510	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
L3Q65_37550	COG2326	polyphosphate kinase activity
L3Q65_37560	COG3620	sequence-specific DNA binding
L3Q65_37625	COG1366	Belongs to the anti-sigma-factor antagonist family
L3Q65_37635	COG1231	oxidoreductase activity
L3Q65_37675	COG3559	Exporter of polyketide antibiotics
L3Q65_37680	COG1131	(ABC) transporter
L3Q65_37725	COG0726	polysaccharide deacetylase
L3Q65_37745	COG0287	Prephenate dehydrogenase
L3Q65_37750	COG1902	pentaerythritol trinitrate reductase activity
L3Q65_37750	COG0446	pyridine nucleotide-disulphide oxidoreductase
L3Q65_37795	COG1846	Transcriptional regulator
L3Q65_37840	COG2318	DinB family
L3Q65_37850	COG3033	Beta-eliminating lyase
L3Q65_37925	COG1309	transcriptional regulator
L3Q65_37945	COG4941	Belongs to the sigma-70 factor family
L3Q65_37950	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_37975	COG2130	NADP-dependent
L3Q65_37980	COG0583	DNA-binding transcription factor activity
L3Q65_37985	COG2272	Belongs to the type-B carboxylesterase lipase family
L3Q65_38005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_38030	COG3706	GGDEF domain
L3Q65_38090	COG0582	viral genome integration into host DNA
L3Q65_38175	COG0596	Alpha beta hydrolase
L3Q65_38195	COG0028	Belongs to the TPP enzyme family
L3Q65_38210	COG2217	Heavy metal translocating P-type atpase
L3Q65_38215	COG3199	ATP-NAD kinase
L3Q65_38225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q65_38230	COG0515	serine threonine protein kinase
L3Q65_38250	COG1595	DNA-templated transcription, initiation
L3Q65_38265	COG1278	Cold shock
L3Q65_38305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
L3Q65_38330	COG2233	PERMEase
L3Q65_38335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L3Q65_38345	COG0789	Transcriptional regulator
L3Q65_38375	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
L3Q65_38390	COG1819	glycosyl
L3Q65_38415	COG0154	amidase activity
L3Q65_38445	COG2318	DinB family
L3Q65_38450	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L3Q65_38475	COG2364	Membrane
L3Q65_38480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_38495	COG2733	membrane
L3Q65_38525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L3Q65_38550	COG2986	histidine ammonia-lyase
L3Q65_38555	COG1174	glycine betaine transport
L3Q65_38560	COG1174	glycine betaine transport
L3Q65_38575	COG2130	NADP-dependent
L3Q65_38605	COG1064	alcohol dehydrogenase
L3Q65_38635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
L3Q65_38650	COG0438	transferase activity, transferring glycosyl groups
L3Q65_38665	COG0588	phosphoglycerate mutase activity
L3Q65_38680	COG0667	Aldo Keto reductase
L3Q65_38685	COG5002	protein histidine kinase activity
L3Q65_38715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L3Q65_38760	COG1595	DNA-templated transcription, initiation
L3Q65_38765	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_38790	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
L3Q65_38795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
L3Q65_38800	COG0181	hydroxymethylbilane synthase activity
L3Q65_38805	COG1587	Uroporphyrinogen-III synthase
L3Q65_38805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L3Q65_38830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3Q65_38835	COG1136	(ABC) transporter
L3Q65_38840	COG0577	efflux transmembrane transporter activity
L3Q65_38840	COG1136	(ABC) transporter
L3Q65_38855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
L3Q65_38860	COG0406	alpha-ribazole phosphatase activity
L3Q65_38870	COG0785	Cytochrome C biogenesis protein
L3Q65_38880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L3Q65_38900	COG1522	sequence-specific DNA binding
L3Q65_38910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L3Q65_38945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L3Q65_38950	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
L3Q65_38960	COG0308	aminopeptidase N
L3Q65_38985	COG0438	transferase activity, transferring glycosyl groups
L3Q65_39000	COG2226	methyltransferase
L3Q65_39015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3Q65_39020	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3Q65_39025	COG0649	NAD binding
L3Q65_39040	COG1034	ATP synthesis coupled electron transport
L3Q65_39045	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
L3Q65_39050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3Q65_39055	COG0839	Belongs to the complex I subunit 6 family
L3Q65_39060	COG0713	ATP synthesis coupled electron transport
L3Q65_39065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L3Q65_39075	COG1007	ATP synthesis coupled electron transport
L3Q65_39085	COG0142	geranyltranstransferase activity
L3Q65_39095	COG1013	pyruvate-flavodoxin oxidoreductase activity
L3Q65_39100	COG0674	pyruvate-flavodoxin oxidoreductase activity
L3Q65_39100	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
L3Q65_39110	COG1522	sequence-specific DNA binding
L3Q65_39115	COG1834	amidinotransferase
L3Q65_39120	COG0596	Alpha beta hydrolase
L3Q65_39140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L3Q65_39160	COG0367	asparagine synthase
L3Q65_39205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
L3Q65_39210	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
L3Q65_39220	COG1216	Glycosyl transferase, family 2
L3Q65_39220	COG0463	Glycosyl transferase, family 2
L3Q65_39230	COG4310	Domain of unknown function (DUF2172)
L3Q65_39245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L3Q65_39260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_39295	COG1666	GTP binding
L3Q65_39315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L3Q65_39330	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
L3Q65_39365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L3Q65_39370	COG2030	dehydratase
L3Q65_39385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_39410	COG0081	regulation of translation
L3Q65_39430	COG0222	ribosome binding
L3Q65_39445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L3Q65_39470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L3Q65_39500	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
L3Q65_39595	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
L3Q65_39600	COG0049	tRNA binding
L3Q65_39605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
L3Q65_39615	COG0051	transcription antitermination factor activity, RNA binding
L3Q65_39620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
L3Q65_39625	COG0088	Forms part of the polypeptide exit tunnel
L3Q65_39630	COG0089	rRNA binding
L3Q65_39635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
L3Q65_39640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
L3Q65_39645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
L3Q65_39650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
L3Q65_39665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
L3Q65_39670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
L3Q65_39675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
L3Q65_39680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
L3Q65_39690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
L3Q65_39695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
L3Q65_39700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
L3Q65_39705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
L3Q65_39710	COG1841	ribosomal large subunit assembly
L3Q65_39715	COG0200	Binds to the 23S rRNA
L3Q65_39725	COG0563	adenylate kinase activity
L3Q65_39735	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
L3Q65_39740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L3Q65_39745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
L3Q65_39755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
L3Q65_39760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
L3Q65_39765	COG0202	RNA polymerase activity
L3Q65_39770	COG0203	ribosomal protein L17
L3Q65_39775	COG0101	tRNA pseudouridine synthase activity
L3Q65_39805	COG1404	Belongs to the peptidase S8 family
L3Q65_39815	COG1674	ftsk spoiiie
L3Q65_39820	COG0443	Heat shock 70 kDa protein
L3Q65_39850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
L3Q65_39855	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L3Q65_39860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L3Q65_39885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L3Q65_39895	COG1349	DNA-binding transcription factor activity
L3Q65_39900	COG1070	Carbohydrate kinase
L3Q65_39905	COG3842	ATPase activity
L3Q65_39910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L3Q65_39920	COG0802	atpase or kinase
L3Q65_39930	COG2321	neutral zinc metallopeptidase
L3Q65_39935	COG0477	Major facilitator Superfamily
L3Q65_39940	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
L3Q65_39940	COG0825	malonyl-CoA metabolic process
L3Q65_39945	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_39985	COG0456	acetyltransferase
L3Q65_39990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
L3Q65_40015	COG1215	transferase activity, transferring glycosyl groups
L3Q65_40025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
L3Q65_40030	COG0459	protein refolding
L3Q65_40035	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_40040	COG1309	transcriptional regulator
L3Q65_40100	COG0516	GMP reductase activity
L3Q65_40120	COG0277	FAD linked oxidase domain protein
L3Q65_40130	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_40145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L3Q65_40145	COG0519	Catalyzes the synthesis of GMP from XMP
L3Q65_40185	COG0697	spore germination
L3Q65_40190	COG0583	DNA-binding transcription factor activity
L3Q65_40195	COG0515	serine threonine protein kinase
L3Q65_40200	COG2815	serine threonine protein kinase
L3Q65_40200	COG0515	serine threonine protein kinase
L3Q65_40255	COG0045	succinate-CoA ligase (ADP-forming) activity
L3Q65_40280	COG0138	bifunctional purine biosynthesis protein purh
L3Q65_40300	COG0587	DNA-directed DNA polymerase activity
L3Q65_40315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
L3Q65_40325	COG2814	Major facilitator Superfamily
L3Q65_40330	COG0640	Transcriptional regulator
L3Q65_40335	COG2814	Major facilitator Superfamily
L3Q65_40360	COG2226	methyltransferase
L3Q65_40385	COG1234	tRNA 3'-trailer cleavage
L3Q65_40400	COG0180	Tryptophanyl-tRNA synthetase
L3Q65_40410	COG1295	ribonuclease BN
L3Q65_40415	COG1686	Belongs to the peptidase S11 family
L3Q65_40435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L3Q65_40450	COG2009	succinate dehydrogenase
L3Q65_40455	COG1744	ABC transporter substrate-binding protein PnrA-like
L3Q65_40460	COG3845	ABC transporter
L3Q65_40470	COG1079	Belongs to the binding-protein-dependent transport system permease family
L3Q65_40490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L3Q65_40495	COG2271	Major facilitator Superfamily
L3Q65_40500	COG1309	transcriptional regulator
L3Q65_40545	COG1733	regulation of RNA biosynthetic process
L3Q65_40555	COG1063	alcohol dehydrogenase
L3Q65_40570	COG0395	ABC-type sugar transport system, permease component
L3Q65_40575	COG3842	ATPase activity
L3Q65_40600	COG2124	cytochrome p450
L3Q65_40605	COG2124	cytochrome p450
L3Q65_40650	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_40655	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_40660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
L3Q65_40695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
L3Q65_40705	COG0789	Transcriptional regulator
L3Q65_40710	COG0667	Aldo Keto reductase
L3Q65_40730	COG0475	glutathione-regulated potassium exporter activity
L3Q65_40735	COG0745	RESPONSE REGULATOR receiver
L3Q65_40740	COG4191	Histidine kinase
L3Q65_40750	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L3Q65_40785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L3Q65_40815	COG0515	serine threonine protein kinase
L3Q65_40840	COG1473	amidohydrolase
L3Q65_40840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
L3Q65_40875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L3Q65_40880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L3Q65_40885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L3Q65_40915	COG4770	biotin carboxylase activity
L3Q65_40930	COG1823	symporter activity
L3Q65_40935	COG0424	maF-like protein
L3Q65_40960	COG1309	transcriptional regulator
L3Q65_40975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3Q65_41010	COG3511	phospholipase C
L3Q65_41015	COG0596	Alpha beta hydrolase
L3Q65_41020	COG3903	Transcriptional regulator
L3Q65_41020	COG3629	intracellular signal transduction
L3Q65_41030	COG0791	NLP P60 protein
L3Q65_41030	COG1388	LysM domain
L3Q65_41030	COG3103	Sh3 type 3 domain protein
L3Q65_41045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L3Q65_41065	COG0483	inositol monophosphate 1-phosphatase activity
L3Q65_41070	COG0745	RESPONSE REGULATOR receiver
L3Q65_41075	COG2205	protein histidine kinase activity
L3Q65_41120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L3Q65_41125	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_41155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
L3Q65_41170	COG2259	Doxx family
L3Q65_41180	COG1316	TRANSCRIPTIONal
L3Q65_41185	COG1316	TRANSCRIPTIONal
L3Q65_41275	COG1725	Transcriptional regulator
L3Q65_41285	COG0778	Nitroreductase
L3Q65_41285	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
L3Q65_41290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L3Q65_41305	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L3Q65_41340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3Q65_41355	COG1611	Belongs to the LOG family
L3Q65_41370	COG0463	Glycosyl transferase, family 2
L3Q65_41380	COG1116	anion transmembrane transporter activity
L3Q65_41385	COG4988	ABC transporter
L3Q65_41390	COG1294	oxidase, subunit
L3Q65_41395	COG1271	oxidase subunit
L3Q65_41420	COG2818	Glycosylase
L3Q65_41425	COG1024	Enoyl-CoA hydratase
L3Q65_41435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
L3Q65_41445	COG0583	DNA-binding transcription factor activity
L3Q65_41450	COG2814	Major facilitator Superfamily
L3Q65_41470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3Q65_41475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L3Q65_41495	COG2239	Acts as a magnesium transporter
L3Q65_41500	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
L3Q65_41505	COG0330	HflC and HflK could
L3Q65_41520	COG1960	acyl-CoA dehydrogenase activity
L3Q65_41580	COG0598	Magnesium transport protein CorA
L3Q65_41610	COG0613	PHP domain protein
L3Q65_41615	COG2095	MarC family integral membrane protein
L3Q65_41635	COG0513	Belongs to the DEAD box helicase family
L3Q65_41665	COG2267	carboxylic ester hydrolase activity
L3Q65_41705	COG0243	molybdopterin cofactor binding
L3Q65_41710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q65_41715	COG2223	nitrite transmembrane transporter activity
L3Q65_41720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q65_41720	COG2146	nitrite reductase [NAD(P)H] activity
L3Q65_41725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q65_41725	COG2146	nitrite reductase [NAD(P)H] activity
L3Q65_41755	COG2378	regulation of single-species biofilm formation
L3Q65_41820	COG0714	Associated with various cellular activities
L3Q65_41825	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
L3Q65_41855	COG0612	Peptidase, M16
L3Q65_41875	COG1175	transmembrane transport
L3Q65_41880	COG0395	ABC-type sugar transport system, permease component
L3Q65_41885	COG1486	melibiose metabolic process
L3Q65_41900	COG0640	Transcriptional regulator
L3Q65_41920	COG3265	gluconokinase activity
L3Q65_41950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L3Q65_41970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L3Q65_42035	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
L3Q65_42045	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_42070	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_42075	COG3842	ATPase activity
L3Q65_42080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
L3Q65_42085	COG1176	ABC-type spermidine putrescine transport system, permease component I
L3Q65_42090	COG1177	transmembrane transport
L3Q65_42095	COG0596	Alpha beta hydrolase
L3Q65_42105	COG1968	undecaprenyl-diphosphatase activity
L3Q65_42115	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
L3Q65_42130	COG2318	DinB family
L3Q65_42140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L3Q65_42140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L3Q65_42145	COG0653	protein targeting
L3Q65_42165	COG0174	glutamine synthetase
L3Q65_42170	COG0154	amidase activity
L3Q65_42190	COG1522	sequence-specific DNA binding
L3Q65_42210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L3Q65_42225	COG2080	2 iron, 2 sulfur cluster binding
L3Q65_42230	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
L3Q65_42235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L3Q65_42240	COG0300	oxidoreductase activity
L3Q65_42260	COG4941	Belongs to the sigma-70 factor family
L3Q65_42280	COG1396	sequence-specific DNA binding
L3Q65_42285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q65_42300	COG1228	amidohydrolase
L3Q65_42305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q65_42310	COG1309	transcriptional regulator
L3Q65_42335	COG0640	Transcriptional regulator
L3Q65_42340	COG0798	PFAM Bile acid sodium symporter
L3Q65_42345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L3Q65_42350	COG0640	Transcriptional regulator
L3Q65_42355	COG2226	methyltransferase
L3Q65_42360	COG0174	glutamine synthetase
L3Q65_42435	COG3480	Lon protease (S16) C-terminal proteolytic domain
L3Q65_42445	COG1615	UPF0182 protein
L3Q65_42465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
L3Q65_42470	COG2884	Cell division ATP-binding protein ftsE
L3Q65_42475	COG2177	Part of the ABC transporter FtsEX involved in
L3Q65_42480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
L3Q65_42500	COG2197	response regulator
L3Q65_42505	COG4585	Histidine kinase
L3Q65_42520	COG2226	methyltransferase
L3Q65_42540	COG2986	histidine ammonia-lyase
L3Q65_42545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
L3Q65_42560	COG1228	amidohydrolase
L3Q65_42565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_42590	COG4585	Histidine kinase
L3Q65_42595	COG2197	response regulator
L3Q65_42615	COG1131	(ABC) transporter
L3Q65_42620	COG1643	Atp-dependent helicase
L3Q65_42625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q65_42645	COG0791	NLP P60 protein
L3Q65_42645	COG3883	PFAM NLP P60 protein
L3Q65_42660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L3Q65_42660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L3Q65_42665	COG0187	DNA topoisomerase II activity
L3Q65_42700	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3Q65_42705	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3Q65_42710	COG1129	ABC transporter
L3Q65_42715	COG1879	ABC-type sugar transport system periplasmic component
L3Q65_42720	COG1609	Transcriptional regulator
L3Q65_42730	COG0469	pyruvate kinase activity
L3Q65_42740	COG0596	Alpha beta hydrolase
L3Q65_42745	COG5640	endopeptidase activity
L3Q65_42830	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_42840	COG3706	GGDEF domain
L3Q65_42855	COG0515	serine threonine protein kinase
L3Q65_42855	COG2815	serine threonine protein kinase
L3Q65_42865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L3Q65_42895	COG0583	DNA-binding transcription factor activity
L3Q65_42920	COG2814	Major facilitator Superfamily
L3Q65_42940	COG1309	transcriptional regulator
L3Q65_42945	COG2353	YceI-like domain
L3Q65_42955	COG0435	Glutathione S-transferase
L3Q65_42990	COG3844	kynureninase activity
L3Q65_42995	COG0531	amino acid
L3Q65_43000	COG1234	tRNA 3'-trailer cleavage
L3Q65_43015	COG1247	-acetyltransferase
L3Q65_43020	COG1396	sequence-specific DNA binding
L3Q65_43040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L3Q65_43050	COG2801	Transposase and inactivated derivatives
L3Q65_43055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3Q65_43090	COG4585	Histidine kinase
L3Q65_43095	COG2197	response regulator
L3Q65_43110	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_43130	COG2197	response regulator
L3Q65_43155	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
L3Q65_43170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3Q65_43175	COG4585	Histidine kinase
L3Q65_43260	COG0740	serine-type endopeptidase activity
L3Q65_43265	COG0740	serine-type endopeptidase activity
L3Q65_43270	COG1396	sequence-specific DNA binding
L3Q65_43280	COG0076	glutamate decarboxylase activity
L3Q65_43295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L3Q65_43315	COG1175	transmembrane transport
L3Q65_43320	COG0395	ABC-type sugar transport system, permease component
L3Q65_43335	COG1846	Transcriptional regulator
L3Q65_43345	COG3458	cephalosporin-C deacetylase activity
L3Q65_43365	COG1609	Transcriptional regulator
L3Q65_43370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L3Q65_43375	COG2814	Major facilitator Superfamily
L3Q65_43380	COG0656	L-ascorbic acid biosynthetic process
L3Q65_43450	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
L3Q65_43460	COG1846	Transcriptional regulator
L3Q65_43495	COG0745	RESPONSE REGULATOR receiver
L3Q65_43500	COG2205	protein histidine kinase activity
L3Q65_43505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
L3Q65_43510	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
L3Q65_43515	COG1181	Belongs to the D-alanine--D-alanine ligase family
L3Q65_43525	COG3629	intracellular signal transduction
L3Q65_43525	COG3903	Transcriptional regulator
L3Q65_43555	COG3903	Transcriptional regulator
L3Q65_43555	COG3629	intracellular signal transduction
L3Q65_43565	COG2197	response regulator
L3Q65_43570	COG4585	Histidine kinase
L3Q65_43605	COG0702	epimerase
L3Q65_43620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3Q65_43635	COG2197	response regulator
L3Q65_43645	COG0577	efflux transmembrane transporter activity
L3Q65_43645	COG1136	(ABC) transporter
L3Q65_43655	COG1233	COG1233 Phytoene dehydrogenase and related
L3Q65_43660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3Q65_43675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L3Q65_43705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L3Q65_43730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3Q65_43735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3Q65_43780	COG0543	2 iron, 2 sulfur cluster binding
L3Q65_43780	COG0633	Ferredoxin
L3Q65_43815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q65_43820	COG0765	amino acid transport
L3Q65_43825	COG1126	abc transporter atp-binding protein
L3Q65_43835	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
L3Q65_43845	COG1131	(ABC) transporter
L3Q65_43850	COG0842	Transport permease protein
L3Q65_43920	COG3629	intracellular signal transduction
L3Q65_43920	COG3903	Transcriptional regulator
L3Q65_43940	COG4221	oxidoreductase activity
L3Q65_43945	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
L3Q65_43960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3Q65_43990	COG0513	Belongs to the DEAD box helicase family
L3Q65_44005	COG2183	response to ionizing radiation
L3Q65_44015	COG2072	flavoprotein involved in K transport
L3Q65_44035	COG2814	Major facilitator Superfamily
L3Q65_44050	COG0477	Major facilitator Superfamily
L3Q65_44065	COG4977	sequence-specific DNA binding
L3Q65_44075	COG1309	transcriptional regulator
L3Q65_44090	COG2030	dehydratase
L3Q65_44090	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_44095	COG3396	Phenylacetate-CoA oxygenase
L3Q65_44100	COG3460	Phenylacetate-CoA oxygenase
L3Q65_44105	COG3396	Phenylacetate-CoA oxygenase
L3Q65_44110	COG2151	metal-sulfur cluster biosynthetic enzyme
L3Q65_44115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3Q65_44120	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
L3Q65_44150	COG0346	lactoylglutathione lyase activity
L3Q65_44155	COG0183	Belongs to the thiolase family
L3Q65_44170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3Q65_44175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L3Q65_44180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q65_44190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q65_44200	COG3279	Response regulator of the LytR AlgR family
L3Q65_44205	COG3275	phosphorelay sensor kinase activity
L3Q65_44210	COG1879	ABC-type sugar transport system periplasmic component
L3Q65_44215	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3Q65_44230	COG1609	Transcriptional regulator
L3Q65_44235	COG3537	Alpha-1,2-mannosidase
L3Q65_44240	COG3537	Alpha-1,2-mannosidase
L3Q65_44250	COG1846	Transcriptional regulator
L3Q65_44275	COG0058	SHG alpha-glucan phosphorylase activity
L3Q65_44290	COG1119	ATPase activity
L3Q65_44295	COG1024	Enoyl-CoA hydratase
L3Q65_44300	COG2226	methyltransferase
L3Q65_44315	COG3979	chitinase
L3Q65_44320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L3Q65_44325	COG2329	Antibiotic biosynthesis monooxygenase
L3Q65_44330	COG0492	ferredoxin-NADP+ reductase activity
L3Q65_44355	COG0745	RESPONSE REGULATOR receiver
L3Q65_44360	COG2205	protein histidine kinase activity
L3Q65_44365	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q65_44380	COG1309	transcriptional regulator
L3Q65_44385	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_44390	COG1309	transcriptional regulator
L3Q65_44405	COG0791	NLP P60 protein
L3Q65_44405	COG3883	PFAM NLP P60 protein
L3Q65_44415	COG0110	maltose O-acetyltransferase activity
L3Q65_44440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L3Q65_44445	COG2076	Multidrug Resistance protein
L3Q65_44455	COG0596	Alpha beta hydrolase
L3Q65_44475	COG0386	Belongs to the glutathione peroxidase family
L3Q65_44485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L3Q65_44495	COG1307	EDD domain protein, DegV family
L3Q65_44505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
L3Q65_44535	COG0482	sulfurtransferase activity
L3Q65_44550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q65_44575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L3Q65_44595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L3Q65_44600	COG0154	amidase activity
L3Q65_44605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L3Q65_44630	COG0129	dihydroxy-acid dehydratase activity
L3Q65_44645	COG0440	acetolactate synthase activity
L3Q65_44650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
L3Q65_44720	COG1404	Belongs to the peptidase S8 family
L3Q65_44725	COG0473	3-isopropylmalate dehydrogenase activity
L3Q65_44730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3Q65_44735	COG1120	ATPase activity
L3Q65_44745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L3Q65_44750	COG0179	Fumarylacetoacetate (FAA) hydrolase
L3Q65_44755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_44795	COG4176	ABC-type proline glycine betaine transport system permease component
L3Q65_44800	COG3448	diguanylate cyclase activity
L3Q65_44800	COG4175	Glycine betaine
L3Q65_44815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
L3Q65_44820	COG0066	3-isopropylmalate dehydratase activity
L3Q65_44825	COG0776	regulation of translation
L3Q65_44835	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
L3Q65_44840	COG1920	GTP binding
L3Q65_44850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
L3Q65_44860	COG0252	asparaginase activity
L3Q65_44875	COG0745	RESPONSE REGULATOR receiver
L3Q65_44880	COG2205	protein histidine kinase activity
L3Q65_44890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_44905	COG1090	epimerase
L3Q65_44910	COG1595	DNA-templated transcription, initiation
L3Q65_44915	COG0477	Major facilitator Superfamily
L3Q65_44940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L3Q65_44945	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
L3Q65_44955	COG0227	Belongs to the bacterial ribosomal protein bL28 family
L3Q65_44960	COG1461	Dihydroxyacetone kinase
L3Q65_44970	COG3209	COG3209 Rhs family protein
L3Q65_44990	COG1404	Belongs to the peptidase S8 family
L3Q65_44995	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L3Q65_45055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L3Q65_45080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L3Q65_45095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q65_45100	COG3973	AAA domain
L3Q65_45105	COG0742	ribosomal rna small subunit methyltransferase
L3Q65_45110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
L3Q65_45130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L3Q65_45135	COG0571	ribonuclease III activity
L3Q65_45140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L3Q65_45150	COG1309	transcriptional regulator
L3Q65_45175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
L3Q65_45180	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_45190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
L3Q65_45190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
L3Q65_45195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
L3Q65_45200	COG0509	glycine decarboxylation via glycine cleavage system
L3Q65_45205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
L3Q65_45210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L3Q65_45215	COG1760	l-serine dehydratase
L3Q65_45230	COG2186	Transcriptional regulator
L3Q65_45235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3Q65_45240	COG1120	ATPase activity
L3Q65_45245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q65_45250	COG4221	oxidoreductase activity
L3Q65_45265	COG2814	Major facilitator Superfamily
L3Q65_45270	COG0179	Fumarylacetoacetate (FAA) hydrolase
L3Q65_45275	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q65_45290	COG1129	ABC transporter
L3Q65_45295	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3Q65_45300	COG2186	Transcriptional regulator
L3Q65_45340	COG1929	Belongs to the glycerate kinase type-1 family
L3Q65_45350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L3Q65_45355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3Q65_45365	COG3485	protocatechuate 3,4-dioxygenase
L3Q65_45370	COG3485	protocatechuate 3,4-dioxygenase
L3Q65_45375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L3Q65_45380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3Q65_45385	COG1414	Transcriptional regulator
L3Q65_45390	COG0746	molybdenum cofactor guanylyltransferase activity
L3Q65_45430	COG3706	GGDEF domain
L3Q65_45475	COG1082	Xylose isomerase domain protein TIM barrel
L3Q65_45480	COG1609	Transcriptional regulator
L3Q65_45485	COG0673	inositol 2-dehydrogenase activity
L3Q65_45490	COG1309	transcriptional regulator
L3Q65_45495	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q65_45505	COG0367	asparagine synthase
L3Q65_45515	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L3Q65_45520	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L3Q65_45525	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
L3Q65_45550	COG1254	Belongs to the acylphosphatase family
L3Q65_45575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q65_45580	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L3Q65_45595	COG1414	Transcriptional regulator
L3Q65_45600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L3Q65_45615	COG0326	Molecular chaperone. Has ATPase activity
L3Q65_45635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L3Q65_45640	COG1309	transcriptional regulator
L3Q65_45645	COG2233	PERMEase
L3Q65_45655	COG2351	hydroxyisourate hydrolase activity
L3Q65_45670	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L3Q65_45675	COG4266	Belongs to the allantoicase family
L3Q65_45705	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L3Q65_45715	COG1832	CoA-binding protein
L3Q65_45720	COG2873	o-acetylhomoserine
L3Q65_45745	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
L3Q65_45785	COG0228	four-way junction DNA binding
L3Q65_45795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L3Q65_45805	COG0336	Belongs to the RNA methyltransferase TrmD family
L3Q65_45810	COG0335	large ribosomal subunit rRNA binding
L3Q65_45815	COG0681	Belongs to the peptidase S26 family
L3Q65_45820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L3Q65_45835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L3Q65_46250	COG0792	nuclease activity
L3Q65_46275	COG1191	sigma factor activity
L3Q65_46285	COG0052	Belongs to the universal ribosomal protein uS2 family
L3Q65_46290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
L3Q65_46295	COG0528	UMP kinase activity
L3Q65_46300	COG0233	cytoplasmic translational termination
L3Q65_46315	COG2226	methyltransferase
L3Q65_46320	COG1695	Transcriptional regulator
L3Q65_46325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L3Q65_46350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L3Q65_46360	COG2070	2-Nitropropane dioxygenase
L3Q65_46380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
L3Q65_46390	COG1231	oxidoreductase activity
L3Q65_46410	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_46420	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L3Q65_46425	COG0439	Biotin carboxylase
L3Q65_46445	COG1012	belongs to the aldehyde dehydrogenase family
L3Q65_46450	COG2072	flavoprotein involved in K transport
L3Q65_46455	COG0657	acetylesterase activity
L3Q65_46460	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q65_46465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
L3Q65_46575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q65_46585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L3Q65_46635	COG1846	Transcriptional regulator
L3Q65_46645	COG0277	FAD linked oxidase domain protein
L3Q65_46650	COG2814	Major facilitator Superfamily
L3Q65_46660	COG2814	Major facilitator Superfamily
L3Q65_46665	COG0431	NADPH-dependent FMN reductase
L3Q65_46675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L3Q65_46685	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
L3Q65_46695	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
L3Q65_46705	COG1309	transcriptional regulator
L3Q65_46735	COG2207	Transcriptional regulator
L3Q65_46745	COG3345	alpha-galactosidase
L3Q65_46750	COG0454	-acetyltransferase
L3Q65_46750	COG0456	acetyltransferase
L3Q65_46765	COG2186	Transcriptional regulator
L3Q65_46770	COG2807	transmembrane transport
L3Q65_46805	COG0513	Belongs to the DEAD box helicase family
L3Q65_46815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q65_46825	COG0667	Aldo Keto reductase
L3Q65_46835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q65_46840	COG3022	response to hydroperoxide
L3Q65_46855	COG0442	prolyl-tRNA aminoacylation
L3Q65_46865	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L3Q65_46880	COG2197	response regulator
L3Q65_46910	COG0346	lactoylglutathione lyase activity
L3Q65_46960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3Q65_46975	COG4152	abc transporter atp-binding protein
L3Q65_46980	COG1668	transmembrane transport
L3Q65_46990	COG3201	nicotinamide mononucleotide transporter
L3Q65_47005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
L3Q65_47035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L3Q65_47045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L3Q65_47060	COG1113	amino acid transport
L3Q65_47065	COG2186	Transcriptional regulator
L3Q65_47070	COG0587	DNA-directed DNA polymerase activity
L3Q65_47075	COG0477	Major facilitator Superfamily
L3Q65_47105	COG1376	ErfK ybiS ycfS ynhG family protein
L3Q65_47110	COG4667	esterase of the alpha-beta hydrolase superfamily
L3Q65_47115	COG0586	Pfam SNARE associated Golgi protein
L3Q65_47120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L3Q65_47125	COG1131	(ABC) transporter
L3Q65_47135	COG0745	RESPONSE REGULATOR receiver
L3Q65_47140	COG2205	protein histidine kinase activity
L3Q65_47165	COG0321	lipoyl(octanoyl) transferase activity
L3Q65_47175	COG1090	epimerase
L3Q65_47190	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3Q65_47195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3Q65_47230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L3Q65_47240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
L3Q65_47245	COG0667	Aldo Keto reductase
L3Q65_47265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L3Q65_47275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor