locus-tag	class	description
HUT10_00010	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUT10_00015	COG2367	Beta-lactamase
HUT10_00045	COG0709	Synthesizes selenophosphate from selenide and ATP
HUT10_00055	COG1921	L-seryl-tRNASec selenium transferase activity
HUT10_00070	COG4221	oxidoreductase activity
HUT10_00075	COG0596	Alpha beta hydrolase
HUT10_00100	COG3250	beta-galactosidase activity
HUT10_00115	COG2197	response regulator
HUT10_00120	COG4585	Histidine kinase
HUT10_00125	COG0463	Glycosyl transferase, family 2
HUT10_00130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUT10_00140	COG3293	Transposase
HUT10_00150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT10_00195	COG4941	Belongs to the sigma-70 factor family
HUT10_00225	COG0515	serine threonine protein kinase
HUT10_00230	COG3321	synthase
HUT10_00230	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_00230	COG0604	alcohol dehydrogenase
HUT10_00235	COG0789	Transcriptional regulator
HUT10_00265	COG0784	Response regulator, receiver
HUT10_00310	COG0300	oxidoreductase activity
HUT10_00340	COG4221	oxidoreductase activity
HUT10_00350	COG1879	ABC-type sugar transport system periplasmic component
HUT10_00370	COG0346	lactoylglutathione lyase activity
HUT10_00375	COG0400	carboxylic ester hydrolase activity
HUT10_00380	COG2208	phosphoserine phosphatase activity
HUT10_00380	COG2770	Histidine kinase
HUT10_00395	COG0577	efflux transmembrane transporter activity
HUT10_00395	COG1136	(ABC) transporter
HUT10_00405	COG4585	Histidine kinase
HUT10_00410	COG2197	response regulator
HUT10_00450	COG0488	(ABC) transporter
HUT10_00455	COG0395	ABC-type sugar transport system, permease component
HUT10_00480	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT10_00490	COG2318	DinB family
HUT10_00495	COG1120	ATPase activity
HUT10_00500	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT10_00505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT10_00515	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT10_00535	COG1132	(ABC) transporter
HUT10_00540	COG1132	(ABC) transporter
HUT10_00565	COG0583	DNA-binding transcription factor activity
HUT10_00585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_00590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_00595	COG1116	anion transmembrane transporter activity
HUT10_00630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_00635	COG2211	Major facilitator Superfamily
HUT10_00640	COG0076	glutamate decarboxylase activity
HUT10_00660	COG2814	Major facilitator Superfamily
HUT10_00680	COG0523	cobalamin synthesis protein
HUT10_00700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT10_00705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT10_00710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT10_00715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT10_00745	COG1024	Enoyl-CoA hydratase
HUT10_00750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_00780	COG1716	ATPase activity
HUT10_00795	COG0789	Transcriptional regulator
HUT10_00800	COG3118	belongs to the thioredoxin family
HUT10_00800	COG0492	ferredoxin-NADP+ reductase activity
HUT10_00815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT10_00815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT10_00835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT10_00880	COG1309	transcriptional regulator
HUT10_00905	COG2267	carboxylic ester hydrolase activity
HUT10_00910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT10_00915	COG0583	DNA-binding transcription factor activity
HUT10_00920	COG3572	ergothioneine biosynthetic process
HUT10_00925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT10_00935	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT10_00950	COG1285	pathogenesis
HUT10_00955	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUT10_00960	COG3883	PFAM NLP P60 protein
HUT10_00960	COG0791	NLP P60 protein
HUT10_00965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_00970	COG0746	molybdenum cofactor guanylyltransferase activity
HUT10_00975	COG0714	Associated with various cellular activities
HUT10_00985	COG2304	oxidoreductase activity
HUT10_00995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUT10_01010	COG2205	protein histidine kinase activity
HUT10_01015	COG0745	RESPONSE REGULATOR receiver
HUT10_01020	COG0477	Major facilitator Superfamily
HUT10_01030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUT10_01050	COG4106	trans-aconitate 2-methyltransferase activity
HUT10_01060	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HUT10_01070	COG0215	cysteine-tRNA ligase activity
HUT10_01075	COG0488	(ABC) transporter
HUT10_01115	COG1410	methionine synthase
HUT10_01115	COG0646	methionine synthase
HUT10_01120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT10_01135	COG0140	phosphoribosyl-ATP diphosphatase activity
HUT10_01140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT10_01150	COG1192	Involved in chromosome partitioning
HUT10_01165	COG1994	Peptidase M50
HUT10_01165	COG0517	IMP dehydrogenase activity
HUT10_01185	COG1222	aaa ATPase
HUT10_01205	COG0640	Transcriptional regulator
HUT10_01240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT10_01245	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT10_01260	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT10_01270	COG4221	oxidoreductase activity
HUT10_01280	COG1733	regulation of RNA biosynthetic process
HUT10_01290	COG2378	regulation of single-species biofilm formation
HUT10_01300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT10_01310	COG1597	lipid kinase activity
HUT10_01365	COG2814	Major facilitator Superfamily
HUT10_01380	COG1309	transcriptional regulator
HUT10_01385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT10_01390	COG0583	DNA-binding transcription factor activity
HUT10_01395	COG4221	oxidoreductase activity
HUT10_01415	COG1136	(ABC) transporter
HUT10_01420	COG1136	(ABC) transporter
HUT10_01430	COG3979	chitinase
HUT10_01450	COG3485	protocatechuate 3,4-dioxygenase
HUT10_01460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_01465	COG1414	Transcriptional regulator
HUT10_01470	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_01505	COG1222	aaa ATPase
HUT10_01605	COG2197	response regulator
HUT10_01610	COG2197	response regulator
HUT10_01620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT10_01620	COG1024	Enoyl-CoA hydratase
HUT10_01625	COG3693	PFAM glycoside hydrolase, family 10
HUT10_01675	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT10_01680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_01715	COG0277	FAD linked oxidase domain protein
HUT10_01725	COG1834	amidinotransferase
HUT10_01785	COG0189	ligase activity
HUT10_01805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_01810	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_01870	COG1793	dna ligase
HUT10_01870	COG3285	dna ligase
HUT10_01880	COG1105	Belongs to the carbohydrate kinase PfkB family
HUT10_01895	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT10_01900	COG1063	alcohol dehydrogenase
HUT10_01905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT10_01910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT10_01980	COG0604	alcohol dehydrogenase
HUT10_01980	COG3321	synthase
HUT10_01990	COG3959	Transketolase, thiamine diphosphate binding domain
HUT10_02115	COG0604	alcohol dehydrogenase
HUT10_02115	COG3321	synthase
HUT10_02145	COG1819	glycosyl
HUT10_02150	COG1349	DNA-binding transcription factor activity
HUT10_02165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT10_02175	COG0463	Glycosyl transferase, family 2
HUT10_02180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_02190	COG0494	nUDIX hydrolase
HUT10_02200	COG1435	thymidine kinase activity
HUT10_02235	COG0640	Transcriptional regulator
HUT10_02250	COG1396	sequence-specific DNA binding
HUT10_02265	COG1309	transcriptional regulator
HUT10_02270	COG1960	acyl-CoA dehydrogenase activity
HUT10_02280	COG1309	transcriptional regulator
HUT10_02315	COG2124	cytochrome p450
HUT10_02325	COG4941	Belongs to the sigma-70 factor family
HUT10_02375	COG4941	Belongs to the sigma-70 factor family
HUT10_02405	COG2226	methyltransferase
HUT10_02460	COG0477	Major facilitator Superfamily
HUT10_02500	COG0823	Involved in the tonB-independent uptake of proteins
HUT10_02500	COG4946	Tricorn protease homolog
HUT10_02500	COG1506	peptidase
HUT10_02505	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT10_02530	COG0601	transmembrane transport
HUT10_02540	COG2362	D-Aminopeptidase
HUT10_02545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT10_02575	COG3537	Alpha-1,2-mannosidase
HUT10_02595	COG0039	L-malate dehydrogenase activity
HUT10_02600	COG0740	serine-type endopeptidase activity
HUT10_02615	COG1968	undecaprenyl-diphosphatase activity
HUT10_02620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_02625	COG0667	Aldo Keto reductase
HUT10_02660	COG2267	carboxylic ester hydrolase activity
HUT10_02665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT10_02675	COG1609	Transcriptional regulator
HUT10_02685	COG2301	Belongs to the HpcH HpaI aldolase family
HUT10_02700	COG0583	DNA-binding transcription factor activity
HUT10_02735	COG3285	dna ligase
HUT10_02735	COG1793	dna ligase
HUT10_02760	COG0596	Alpha beta hydrolase
HUT10_02765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_02780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT10_02790	COG2066	Belongs to the glutaminase family
HUT10_02855	COG2252	PERMEase
HUT10_02860	COG0590	tRNA wobble adenosine to inosine editing
HUT10_02880	COG3960	tartronate-semialdehyde synthase activity
HUT10_02885	COG2084	Dehydrogenase
HUT10_02890	COG3622	Belongs to the hyi family
HUT10_02900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_02905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT10_02935	COG1278	Cold shock
HUT10_02955	COG3250	beta-galactosidase activity
HUT10_02970	COG1070	Carbohydrate kinase
HUT10_02980	COG3347	Dehydrogenase
HUT10_02980	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_02990	COG3254	rhamnose metabolic process
HUT10_03005	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_03015	COG1609	Transcriptional regulator
HUT10_03030	COG3629	intracellular signal transduction
HUT10_03030	COG3903	Transcriptional regulator
HUT10_03070	COG0028	Belongs to the TPP enzyme family
HUT10_03075	COG0583	DNA-binding transcription factor activity
HUT10_03080	COG0387	Pfam Sodium calcium exchanger
HUT10_03090	COG3437	response regulator, receiver
HUT10_03090	COG2205	protein histidine kinase activity
HUT10_03090	COG4999	Histidine kinase
HUT10_03090	COG3850	Histidine kinase
HUT10_03100	COG0823	Involved in the tonB-independent uptake of proteins
HUT10_03100	COG4946	Tricorn protease homolog
HUT10_03100	COG1506	peptidase
HUT10_03125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_03130	COG1278	Cold shock
HUT10_03150	COG1609	Transcriptional regulator
HUT10_03160	COG0395	ABC-type sugar transport system, permease component
HUT10_03165	COG1175	transmembrane transport
HUT10_03175	COG1609	Transcriptional regulator
HUT10_03235	COG2267	carboxylic ester hydrolase activity
HUT10_03250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT10_03260	COG3285	dna ligase
HUT10_03260	COG1793	dna ligase
HUT10_03305	COG0477	Major facilitator Superfamily
HUT10_03310	COG3046	protein related to deoxyribodipyrimidine photolyase
HUT10_03360	COG3250	beta-galactosidase activity
HUT10_03385	COG0297	glycogen (starch) synthase activity
HUT10_03400	COG3903	Transcriptional regulator
HUT10_03400	COG3629	intracellular signal transduction
HUT10_03420	COG1090	epimerase
HUT10_03480	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HUT10_03495	COG3903	Transcriptional regulator
HUT10_03495	COG3629	intracellular signal transduction
HUT10_03530	COG0673	inositol 2-dehydrogenase activity
HUT10_03545	COG0395	ABC-type sugar transport system, permease component
HUT10_03550	COG1175	transmembrane transport
HUT10_03555	COG1653	transport
HUT10_03565	COG1609	Transcriptional regulator
HUT10_03570	COG0277	FAD linked oxidase domain protein
HUT10_03630	COG0604	alcohol dehydrogenase
HUT10_03635	COG0137	argininosuccinate synthase activity
HUT10_03650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT10_03655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT10_03665	COG1414	Transcriptional regulator
HUT10_03670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT10_03695	COG1609	Transcriptional regulator
HUT10_03705	COG4214	carbohydrate transport
HUT10_03710	COG1129	ABC transporter
HUT10_03720	COG2160	L-arabinose isomerase activity
HUT10_03740	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_03745	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_03755	COG1879	ABC-type sugar transport system periplasmic component
HUT10_03770	COG1686	Belongs to the peptidase S11 family
HUT10_03785	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_03800	COG1470	cell adhesion involved in biofilm formation
HUT10_03800	COG0366	Alpha amylase catalytic
HUT10_03805	COG1609	Transcriptional regulator
HUT10_03830	COG0302	gtp cyclohydrolase
HUT10_03895	COG4991	sh3 domain protein
HUT10_03900	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_03905	COG0395	ABC-type sugar transport system, permease component
HUT10_03910	COG1175	transmembrane transport
HUT10_03915	COG2182	Extracellular solute-binding protein
HUT10_03925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT10_03935	COG0477	Major facilitator Superfamily
HUT10_03950	COG0247	lactate metabolic process
HUT10_03950	COG2181	nitrate reductase activity
HUT10_03965	COG1716	ATPase activity
HUT10_03965	COG5001	Diguanylate cyclase
HUT10_03975	COG2124	cytochrome p450
HUT10_03985	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_03990	COG1609	Transcriptional regulator
HUT10_04000	COG1175	transmembrane transport
HUT10_04005	COG0395	ABC-type sugar transport system, permease component
HUT10_04020	COG1309	transcriptional regulator
HUT10_04025	COG2353	YceI-like domain
HUT10_04030	COG1846	Transcriptional regulator
HUT10_04035	COG0435	Glutathione S-transferase
HUT10_04045	COG0596	Alpha beta hydrolase
HUT10_04065	COG0459	protein refolding
HUT10_04070	COG1063	alcohol dehydrogenase
HUT10_04110	COG3284	Transcriptional regulator
HUT10_04135	COG3835	regulator
HUT10_04160	COG0596	Alpha beta hydrolase
HUT10_04225	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_04235	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_04250	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT10_04260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT10_04275	COG0300	oxidoreductase activity
HUT10_04295	COG1959	2 iron, 2 sulfur cluster binding
HUT10_04295	COG1295	ribonuclease BN
HUT10_04315	COG2936	dipeptidyl-peptidase activity
HUT10_04340	COG0297	glycogen (starch) synthase activity
HUT10_04345	COG0463	Glycosyl transferase, family 2
HUT10_04345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT10_04365	COG2192	nodulation
HUT10_04370	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUT10_04375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUT10_04375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUT10_04380	COG0300	oxidoreductase activity
HUT10_04390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT10_04410	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_04415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUT10_04420	COG0859	PFAM glycosyl transferase family 9
HUT10_04430	COG0248	Ppx GppA phosphatase
HUT10_04440	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_04485	COG0326	Molecular chaperone. Has ATPase activity
HUT10_04545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT10_04565	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT10_04575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT10_04615	COG2267	carboxylic ester hydrolase activity
HUT10_04645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT10_04665	COG3634	alkyl hydroperoxide reductase activity
HUT10_04680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT10_04685	COG0456	acetyltransferase
HUT10_04685	COG1846	Transcriptional regulator
HUT10_04755	COG1793	dna ligase
HUT10_04755	COG3285	dna ligase
HUT10_04815	COG4106	trans-aconitate 2-methyltransferase activity
HUT10_04840	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_04865	COG0477	Major facilitator Superfamily
HUT10_04905	COG0439	Biotin carboxylase
HUT10_04930	COG0583	DNA-binding transcription factor activity
HUT10_04940	COG2855	membrane
HUT10_04955	COG4585	Histidine kinase
HUT10_04960	COG2197	response regulator
HUT10_04980	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HUT10_05010	COG1793	dna ligase
HUT10_05015	COG2318	DinB family
HUT10_05030	COG0477	Major facilitator Superfamily
HUT10_05050	COG3903	Transcriptional regulator
HUT10_05050	COG3629	intracellular signal transduction
HUT10_05065	COG1846	Transcriptional regulator
HUT10_05095	COG2124	cytochrome p450
HUT10_05110	COG1609	Transcriptional regulator
HUT10_05135	COG0531	amino acid
HUT10_05140	COG1940	carbohydrate kinase activity
HUT10_05185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_05190	COG1309	transcriptional regulator
HUT10_05220	COG1063	alcohol dehydrogenase
HUT10_05235	COG1864	DNA RNA non-specific endonuclease
HUT10_05235	COG3591	Belongs to the peptidase S1B family
HUT10_05240	COG1802	Transcriptional regulator
HUT10_05255	COG1960	acyl-CoA dehydrogenase activity
HUT10_05260	COG1960	acyl-CoA dehydrogenase activity
HUT10_05270	COG1024	Enoyl-CoA hydratase
HUT10_05275	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_05280	COG1960	acyl-CoA dehydrogenase activity
HUT10_05285	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_05290	COG0183	Belongs to the thiolase family
HUT10_05295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_05315	COG1024	Enoyl-CoA hydratase
HUT10_05320	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_05355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_05370	COG0477	Major facilitator Superfamily
HUT10_05375	COG2409	Drug exporters of the RND superfamily
HUT10_05400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_05405	COG0484	heat shock protein binding
HUT10_05410	COG1280	lysine exporter protein (LysE YggA)
HUT10_05440	COG2357	RelA SpoT domain protein
HUT10_05490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_05495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_05500	COG2080	2 iron, 2 sulfur cluster binding
HUT10_05510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_05530	COG3591	Belongs to the peptidase S1B family
HUT10_05565	COG3706	GGDEF domain
HUT10_05575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT10_05585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT10_05595	COG2182	Extracellular solute-binding protein
HUT10_05600	COG1175	transmembrane transport
HUT10_05605	COG0395	ABC-type sugar transport system, permease component
HUT10_05615	COG2188	Transcriptional regulator
HUT10_05635	COG2018	Roadblock/LC7 domain
HUT10_05660	COG0028	Belongs to the TPP enzyme family
HUT10_05670	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_05685	COG1309	transcriptional regulator
HUT10_05780	COG2197	response regulator
HUT10_05810	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT10_05835	COG1024	Enoyl-CoA hydratase
HUT10_05840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_05890	COG3285	dna ligase
HUT10_05890	COG1793	dna ligase
HUT10_05900	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT10_05955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_05965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_05975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_05975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_05985	COG3938	Belongs to the proline racemase family
HUT10_05990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_06020	COG3511	phospholipase C
HUT10_06025	COG1846	Transcriptional regulator
HUT10_06050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT10_06055	COG1053	succinate dehydrogenase
HUT10_06065	COG0583	DNA-binding transcription factor activity
HUT10_06070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_06105	COG2318	DinB family
HUT10_06120	COG2271	Major facilitator Superfamily
HUT10_06125	COG0243	molybdopterin cofactor binding
HUT10_06130	COG3383	formate dehydrogenase (NAD+) activity
HUT10_06130	COG0243	molybdopterin cofactor binding
HUT10_06135	COG0437	4 iron, 4 sulfur cluster binding
HUT10_06160	COG1609	Transcriptional regulator
HUT10_06165	COG1349	DNA-binding transcription factor activity
HUT10_06180	COG1175	transmembrane transport
HUT10_06185	COG0395	ABC-type sugar transport system, permease component
HUT10_06230	COG1595	DNA-templated transcription, initiation
HUT10_06235	COG0366	Alpha amylase catalytic
HUT10_06275	COG0477	Major facilitator Superfamily
HUT10_06280	COG0628	permease
HUT10_06325	COG0477	Major facilitator Superfamily
HUT10_06330	COG3387	PFAM Glycoside hydrolase 15-related
HUT10_06345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT10_06375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT10_06405	COG1960	acyl-CoA dehydrogenase activity
HUT10_06410	COG1960	acyl-CoA dehydrogenase activity
HUT10_06415	COG1960	acyl-CoA dehydrogenase activity
HUT10_06425	COG0596	Alpha beta hydrolase
HUT10_06435	COG1309	transcriptional regulator
HUT10_06445	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_06455	COG3250	beta-galactosidase activity
HUT10_06470	COG1131	(ABC) transporter
HUT10_06490	COG5002	protein histidine kinase activity
HUT10_06495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT10_06500	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_06505	COG0395	ABC-type sugar transport system, permease component
HUT10_06515	COG2186	Transcriptional regulator
HUT10_06520	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_06530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_06535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_06615	COG2222	sugar isomerase
HUT10_06620	COG1349	DNA-binding transcription factor activity
HUT10_06640	COG0395	ABC-type sugar transport system, permease component
HUT10_06645	COG1486	melibiose metabolic process
HUT10_06655	COG3345	alpha-galactosidase
HUT10_06665	COG0583	DNA-binding transcription factor activity
HUT10_06670	COG0438	transferase activity, transferring glycosyl groups
HUT10_06685	COG2144	transferase activity, transferring acyl groups
HUT10_06705	COG2072	flavoprotein involved in K transport
HUT10_06720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT10_06735	COG2205	protein histidine kinase activity
HUT10_06745	COG0531	amino acid
HUT10_06790	COG1073	alpha beta
HUT10_06795	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_06800	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_06810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_06840	COG1595	DNA-templated transcription, initiation
HUT10_06865	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_06870	COG1129	ABC transporter
HUT10_06905	COG1309	transcriptional regulator
HUT10_06925	COG2197	response regulator
HUT10_06930	COG4585	Histidine kinase
HUT10_06955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT10_06960	COG0640	Transcriptional regulator
HUT10_06975	COG0693	protein deglycase activity
HUT10_06980	COG1063	alcohol dehydrogenase
HUT10_07020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_07025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_07030	COG0583	DNA-binding transcription factor activity
HUT10_07095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_07105	COG1116	anion transmembrane transporter activity
HUT10_07110	COG1053	succinate dehydrogenase
HUT10_07150	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HUT10_07160	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_07165	COG3485	protocatechuate 3,4-dioxygenase
HUT10_07180	COG1414	Transcriptional regulator
HUT10_07200	COG1309	transcriptional regulator
HUT10_07215	COG1309	transcriptional regulator
HUT10_07230	COG0604	alcohol dehydrogenase
HUT10_07230	COG3321	synthase
HUT10_07235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUT10_07315	COG1064	alcohol dehydrogenase
HUT10_07480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_07485	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_07490	COG1309	transcriptional regulator
HUT10_07510	COG4221	oxidoreductase activity
HUT10_07545	COG1659	Linocin_M18 bacteriocin protein
HUT10_07595	COG0477	Major facilitator Superfamily
HUT10_07610	COG1309	transcriptional regulator
HUT10_07620	COG0745	RESPONSE REGULATOR receiver
HUT10_07645	COG1819	glycosyl
HUT10_07685	COG4221	oxidoreductase activity
HUT10_07715	COG1802	Transcriptional regulator
HUT10_07730	COG0473	3-isopropylmalate dehydrogenase activity
HUT10_07735	COG0583	DNA-binding transcription factor activity
HUT10_07740	COG0667	Aldo Keto reductase
HUT10_07745	COG1309	transcriptional regulator
HUT10_07750	COG0133	tryptophan synthase activity
HUT10_07755	COG0159	tryptophan synthase activity
HUT10_07765	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_07775	COG0477	Major facilitator Superfamily
HUT10_07800	COG1388	LysM domain
HUT10_07800	COG3942	CHAP domain
HUT10_07865	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HUT10_07890	COG0747	negative chemotaxis
HUT10_07895	COG0601	transmembrane transport
HUT10_07915	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_07920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT10_07925	COG1063	alcohol dehydrogenase
HUT10_07955	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_07960	COG1802	Transcriptional regulator
HUT10_07965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_07980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT10_08100	COG2197	response regulator
HUT10_08155	COG1302	Protein conserved in bacteria
HUT10_08190	COG0009	L-threonylcarbamoyladenylate synthase
HUT10_08210	COG3209	COG3209 Rhs family protein
HUT10_08210	COG3209	COG3209 Rhs family protein
HUT10_08215	COG1902	pentaerythritol trinitrate reductase activity
HUT10_08220	COG2267	carboxylic ester hydrolase activity
HUT10_08230	COG2843	Capsule synthesis protein
HUT10_08240	COG1473	amidohydrolase
HUT10_08245	COG0477	Major facilitator Superfamily
HUT10_08255	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HUT10_08270	COG1960	acyl-CoA dehydrogenase activity
HUT10_08295	COG2197	response regulator
HUT10_08300	COG3903	Transcriptional regulator
HUT10_08300	COG3629	intracellular signal transduction
HUT10_08305	COG1414	Transcriptional regulator
HUT10_08310	COG3971	2-oxopent-4-enoate hydratase activity
HUT10_08315	COG4569	acetaldehyde dehydrogenase (acetylating) activity
HUT10_08320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT10_08415	COG3511	phospholipase C
HUT10_08450	COG1846	Transcriptional regulator
HUT10_08465	COG3629	intracellular signal transduction
HUT10_08465	COG3903	Transcriptional regulator
HUT10_08470	COG0477	Major facilitator Superfamily
HUT10_08485	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_08495	COG1024	Enoyl-CoA hydratase
HUT10_08505	COG0492	ferredoxin-NADP+ reductase activity
HUT10_08515	COG3384	dioxygenase
HUT10_08540	COG1414	Transcriptional regulator
HUT10_08545	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT10_08575	COG3321	synthase
HUT10_08575	COG0604	alcohol dehydrogenase
HUT10_08590	COG5001	Diguanylate cyclase
HUT10_08620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT10_08690	COG0642	Histidine kinase
HUT10_08690	COG3850	Histidine kinase
HUT10_08705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_08725	COG1653	transport
HUT10_08750	COG0583	DNA-binding transcription factor activity
HUT10_08760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_08770	COG1126	abc transporter atp-binding protein
HUT10_08795	COG0596	Alpha beta hydrolase
HUT10_08795	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_08820	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_08890	COG3387	PFAM Glycoside hydrolase 15-related
HUT10_08905	COG1595	DNA-templated transcription, initiation
HUT10_08910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_08940	COG2255	four-way junction helicase activity
HUT10_09005	COG5492	domain, Protein
HUT10_09005	COG4932	domain protein
HUT10_09040	COG1595	DNA-templated transcription, initiation
HUT10_09140	COG0671	phosphoesterase, PA-phosphatase related
HUT10_09160	COG0366	Alpha amylase catalytic
HUT10_09165	COG1609	Transcriptional regulator
HUT10_09190	COG2508	Transcriptional regulator
HUT10_09195	COG1609	Transcriptional regulator
HUT10_09250	COG2409	Drug exporters of the RND superfamily
HUT10_09270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT10_09275	COG1285	pathogenesis
HUT10_09285	COG1116	anion transmembrane transporter activity
HUT10_09360	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT10_09365	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT10_09370	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT10_09390	COG0531	amino acid
HUT10_09520	COG3415	Transposase
HUT10_09520	COG2801	Transposase and inactivated derivatives
HUT10_09545	COG2175	clavaminate synthase activity
HUT10_09630	COG1674	ftsk spoiiie
HUT10_09640	COG3629	intracellular signal transduction
HUT10_09640	COG3903	Transcriptional regulator
HUT10_09665	COG0653	protein targeting
HUT10_09680	COG1404	Belongs to the peptidase S8 family
HUT10_09690	COG0464	growth
HUT10_09720	COG2197	response regulator
HUT10_09745	COG3903	Transcriptional regulator
HUT10_09745	COG3629	intracellular signal transduction
HUT10_09750	COG3903	Transcriptional regulator
HUT10_09750	COG3629	intracellular signal transduction
HUT10_09755	COG2197	response regulator
HUT10_09765	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUT10_09770	COG3903	Transcriptional regulator
HUT10_09770	COG3629	intracellular signal transduction
HUT10_09780	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_09805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT10_09855	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_09875	COG2986	histidine ammonia-lyase
HUT10_09890	COG2132	Multicopper oxidase
HUT10_09925	COG0477	Major facilitator Superfamily
HUT10_09935	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT10_09945	COG0006	proline dipeptidase activity
HUT10_09955	COG2124	cytochrome p450
HUT10_09965	COG0300	oxidoreductase activity
HUT10_09990	COG2124	cytochrome p450
HUT10_09995	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_10030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT10_10040	COG0477	Major facilitator Superfamily
HUT10_10050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_10095	COG0515	serine threonine protein kinase
HUT10_10095	COG2815	serine threonine protein kinase
HUT10_10165	COG0494	nUDIX hydrolase
HUT10_10295	COG0587	DNA-directed DNA polymerase activity
HUT10_10345	COG0587	DNA-directed DNA polymerase activity
HUT10_10425	COG3629	intracellular signal transduction
HUT10_10425	COG3903	Transcriptional regulator
HUT10_10430	COG3903	Transcriptional regulator
HUT10_10430	COG3629	intracellular signal transduction
HUT10_10485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_10490	COG2192	nodulation
HUT10_10525	COG2986	histidine ammonia-lyase
HUT10_10560	COG3903	Transcriptional regulator
HUT10_10560	COG3629	intracellular signal transduction
HUT10_10790	COG1404	Belongs to the peptidase S8 family
HUT10_10900	COG2197	response regulator
HUT10_10920	COG3883	PFAM NLP P60 protein
HUT10_10920	COG0791	NLP P60 protein
HUT10_11010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_11100	COG3903	Transcriptional regulator
HUT10_11100	COG3629	intracellular signal transduction
HUT10_11105	COG3629	intracellular signal transduction
HUT10_11105	COG3903	Transcriptional regulator
HUT10_11125	COG0583	DNA-binding transcription factor activity
HUT10_11140	COG2814	Major facilitator Superfamily
HUT10_11175	COG0154	amidase activity
HUT10_11180	COG0789	Transcriptional regulator
HUT10_11185	COG0640	Transcriptional regulator
HUT10_11210	COG0673	inositol 2-dehydrogenase activity
HUT10_11235	COG1653	transport
HUT10_11265	COG1131	(ABC) transporter
HUT10_11270	COG1725	Transcriptional regulator
HUT10_11275	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HUT10_11280	COG0028	Belongs to the TPP enzyme family
HUT10_11295	COG1522	sequence-specific DNA binding
HUT10_11305	COG2197	response regulator
HUT10_11320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT10_11330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT10_11340	COG0702	epimerase
HUT10_11355	COG0583	DNA-binding transcription factor activity
HUT10_11360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT10_11430	COG0300	oxidoreductase activity
HUT10_11435	COG4221	oxidoreductase activity
HUT10_11440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUT10_11500	COG2318	DinB family
HUT10_11530	COG2267	carboxylic ester hydrolase activity
HUT10_11585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT10_11630	COG2815	serine threonine protein kinase
HUT10_11630	COG0515	serine threonine protein kinase
HUT10_11640	COG0456	acetyltransferase
HUT10_11645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT10_11675	COG3511	phospholipase C
HUT10_11750	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_11815	COG0714	Associated with various cellular activities
HUT10_11825	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT10_11830	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT10_11840	COG1733	regulation of RNA biosynthetic process
HUT10_11850	COG5492	domain, Protein
HUT10_11865	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_11870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_11880	COG1414	Transcriptional regulator
HUT10_11885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_11965	COG1160	GTP binding
HUT10_11995	COG0475	glutathione-regulated potassium exporter activity
HUT10_12005	COG2936	dipeptidyl-peptidase activity
HUT10_12010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_12020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT10_12055	COG0504	CTP synthase activity
HUT10_12075	COG1953	Uracil, thiamine, allantoin
HUT10_12125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT10_12140	COG0647	UMP catabolic process
HUT10_12165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT10_12170	COG2094	Belongs to the DNA glycosylase MPG family
HUT10_12175	COG0165	Argininosuccinate lyase
HUT10_12185	COG1438	arginine binding
HUT10_12190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT10_12195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT10_12200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT10_12205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUT10_12210	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT10_12225	COG0596	Alpha beta hydrolase
HUT10_12235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT10_12235	COG0072	phenylalanine-tRNA ligase activity
HUT10_12240	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT10_12250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT10_12255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT10_12260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUT10_12285	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUT10_12290	COG0251	oxidation-reduction process
HUT10_12310	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT10_12315	COG2610	gluconate transmembrane transporter activity
HUT10_12320	COG2706	6-phosphogluconolactonase activity
HUT10_12330	COG1175	transmembrane transport
HUT10_12335	COG0395	ABC-type sugar transport system, permease component
HUT10_12360	COG4565	transcriptional regulatory protein
HUT10_12365	COG3290	protein histidine kinase activity
HUT10_12370	COG1301	dicarboxylic acid transport
HUT10_12375	COG1733	regulation of RNA biosynthetic process
HUT10_12420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_12450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_12455	COG0328	RNA-DNA hybrid ribonuclease activity
HUT10_12460	COG3012	SEC-C Motif Domain Protein
HUT10_12480	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT10_12490	COG0406	alpha-ribazole phosphatase activity
HUT10_12510	COG1609	Transcriptional regulator
HUT10_12530	COG0823	Involved in the tonB-independent uptake of proteins
HUT10_12530	COG1506	peptidase
HUT10_12530	COG4946	Tricorn protease homolog
HUT10_12540	COG1131	(ABC) transporter
HUT10_12550	COG1024	Enoyl-CoA hydratase
HUT10_12595	COG0237	dephospho-CoA kinase activity
HUT10_12595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUT10_12835	COG0539	negative regulation of cytoplasmic translation
HUT10_12840	COG2226	methyltransferase
HUT10_12860	COG1511	domain protein
HUT10_12875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_12875	COG0604	alcohol dehydrogenase
HUT10_12875	COG3321	synthase
HUT10_12875	COG4221	oxidoreductase activity
HUT10_13030	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_13045	COG1017	nitric oxide dioxygenase activity
HUT10_13045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_13055	COG3903	Transcriptional regulator
HUT10_13055	COG3629	intracellular signal transduction
HUT10_13080	COG4977	sequence-specific DNA binding
HUT10_13105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_13125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_13135	COG0667	Aldo Keto reductase
HUT10_13140	COG0583	DNA-binding transcription factor activity
HUT10_13175	COG1733	regulation of RNA biosynthetic process
HUT10_13185	COG1309	transcriptional regulator
HUT10_13205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_13210	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_13220	COG1404	Belongs to the peptidase S8 family
HUT10_13240	COG1404	Belongs to the peptidase S8 family
HUT10_13280	COG4585	Histidine kinase
HUT10_13285	COG2197	response regulator
HUT10_13310	COG1215	transferase activity, transferring glycosyl groups
HUT10_13315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_13320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT10_13325	COG2909	trisaccharide binding
HUT10_13345	COG0475	glutathione-regulated potassium exporter activity
HUT10_13345	COG0569	domain protein
HUT10_13375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT10_13420	COG3251	PFAM MbtH domain protein
HUT10_13485	COG2814	Major facilitator Superfamily
HUT10_13515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUT10_13520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT10_13525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT10_13535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT10_13540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT10_13555	COG0768	penicillin binding
HUT10_13565	COG0275	rRNA processing
HUT10_13570	COG2001	Belongs to the MraZ family
HUT10_13595	COG0714	Associated with various cellular activities
HUT10_13605	COG1305	Transglutaminase-like
HUT10_13615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT10_13625	COG1192	Involved in chromosome partitioning
HUT10_13630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT10_13635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT10_13645	COG0167	dihydroorotate dehydrogenase activity
HUT10_13650	COG0154	amidase activity
HUT10_13665	COG1396	sequence-specific DNA binding
HUT10_13680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT10_13685	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT10_13705	COG1674	ftsk spoiiie
HUT10_13735	COG1113	amino acid transport
HUT10_13755	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT10_13760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_13765	COG0515	serine threonine protein kinase
HUT10_13850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT10_13860	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT10_13865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT10_13885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUT10_13915	COG2268	Band 7 protein
HUT10_13930	COG4106	trans-aconitate 2-methyltransferase activity
HUT10_13950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT10_13970	COG0195	Participates in both transcription termination and antitermination
HUT10_13975	COG0779	Required for maturation of 30S ribosomal subunits
HUT10_14010	COG3226	Transcriptional regulator
HUT10_14025	COG2197	response regulator
HUT10_14035	COG1733	regulation of RNA biosynthetic process
HUT10_14045	COG1309	transcriptional regulator
HUT10_14050	COG2936	dipeptidyl-peptidase activity
HUT10_14070	COG5002	protein histidine kinase activity
HUT10_14075	COG0583	DNA-binding transcription factor activity
HUT10_14085	COG1024	Enoyl-CoA hydratase
HUT10_14095	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_14100	COG1960	acyl-CoA dehydrogenase activity
HUT10_14105	COG1316	TRANSCRIPTIONal
HUT10_14135	COG0583	DNA-binding transcription factor activity
HUT10_14170	COG0583	DNA-binding transcription factor activity
HUT10_14175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_14260	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT10_14300	COG1595	DNA-templated transcription, initiation
HUT10_14325	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT10_14370	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_14405	COG4106	trans-aconitate 2-methyltransferase activity
HUT10_14420	COG1595	DNA-templated transcription, initiation
HUT10_14455	COG2318	DinB family
HUT10_14470	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT10_14480	COG2197	response regulator
HUT10_14485	COG4585	Histidine kinase
HUT10_14495	COG1131	(ABC) transporter
HUT10_14500	COG0423	glycine-tRNA ligase activity
HUT10_14535	COG0701	Predicted permease
HUT10_14545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT10_14550	COG1381	Involved in DNA repair and RecF pathway recombination
HUT10_14580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT10_14595	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT10_14605	COG0537	adenosine 5'-monophosphoramidase activity
HUT10_14615	COG0484	heat shock protein binding
HUT10_14620	COG1420	regulation of RNA biosynthetic process
HUT10_14645	COG0667	Aldo Keto reductase
HUT10_14685	COG2205	protein histidine kinase activity
HUT10_14690	COG0745	RESPONSE REGULATOR receiver
HUT10_14695	COG1953	Uracil, thiamine, allantoin
HUT10_14705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT10_14745	COG0515	serine threonine protein kinase
HUT10_14745	COG2815	serine threonine protein kinase
HUT10_14755	COG0542	response to heat
HUT10_14765	COG0842	Transport permease protein
HUT10_14765	COG1131	(ABC) transporter
HUT10_14765	COG1716	ATPase activity
HUT10_14820	COG0175	sulfate reduction
HUT10_14850	COG1024	Enoyl-CoA hydratase
HUT10_14855	COG2732	(Barnase) inhibitor
HUT10_14860	COG4290	ribonuclease
HUT10_14870	COG0604	alcohol dehydrogenase
HUT10_14880	COG0531	amino acid
HUT10_14885	COG2070	2-Nitropropane dioxygenase
HUT10_14935	COG2226	methyltransferase
HUT10_14950	COG0268	Binds directly to 16S ribosomal RNA
HUT10_14965	COG0658	competence protein
HUT10_14965	COG2333	competence protein COMEC
HUT10_14975	COG1307	EDD domain protein, DegV family
HUT10_14985	COG0406	alpha-ribazole phosphatase activity
HUT10_14990	COG0799	negative regulation of ribosome biogenesis
HUT10_14995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT10_15005	COG0477	Major facilitator Superfamily
HUT10_15010	COG0018	arginyl-trna synthetase
HUT10_15025	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_15035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT10_15040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT10_15045	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT10_15050	COG1530	ribonuclease E activity
HUT10_15050	COG1530	ribonuclease E activity
HUT10_15070	COG1131	(ABC) transporter
HUT10_15085	COG0105	UTP biosynthetic process
HUT10_15135	COG2366	antibiotic biosynthetic process
HUT10_15150	COG0285	dihydrofolate synthase activity
HUT10_15165	COG0596	Alpha beta hydrolase
HUT10_15165	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_15175	COG0583	DNA-binding transcription factor activity
HUT10_15185	COG0525	valine-tRNA ligase activity
HUT10_15205	COG0477	Major facilitator Superfamily
HUT10_15220	COG1316	TRANSCRIPTIONal
HUT10_15235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT10_15265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT10_15270	COG0740	serine-type endopeptidase activity
HUT10_15275	COG0740	serine-type endopeptidase activity
HUT10_15280	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT10_15290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_15300	COG2205	protein histidine kinase activity
HUT10_15305	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_15370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_15410	COG3537	Alpha-1,2-mannosidase
HUT10_15425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT10_15430	COG3559	Exporter of polyketide antibiotics
HUT10_15435	COG1131	(ABC) transporter
HUT10_15440	COG1309	transcriptional regulator
HUT10_15450	COG1940	carbohydrate kinase activity
HUT10_15450	COG1846	Transcriptional regulator
HUT10_15490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT10_15505	COG2814	Major facilitator Superfamily
HUT10_15510	COG0656	L-ascorbic acid biosynthetic process
HUT10_15540	COG0693	protein deglycase activity
HUT10_15545	COG2208	phosphoserine phosphatase activity
HUT10_15550	COG0784	Response regulator, receiver
HUT10_15550	COG5002	protein histidine kinase activity
HUT10_15575	COG1733	regulation of RNA biosynthetic process
HUT10_15580	COG3345	alpha-galactosidase
HUT10_15605	COG0604	alcohol dehydrogenase
HUT10_15605	COG3321	synthase
HUT10_15700	COG2124	cytochrome p450
HUT10_15725	COG1819	glycosyl
HUT10_15730	COG1131	(ABC) transporter
HUT10_15740	COG2197	response regulator
HUT10_15745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUT10_15795	COG0698	ribose 5-phosphate isomerase
HUT10_15810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT10_15820	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUT10_15835	COG0668	transmembrane transport
HUT10_15845	COG0366	Alpha amylase catalytic
HUT10_15860	COG0824	Thioesterase
HUT10_15865	COG2902	Dehydrogenase
HUT10_15880	COG3336	cytochrome c oxidase
HUT10_15895	COG0738	Major facilitator superfamily
HUT10_15900	COG1609	Transcriptional regulator
HUT10_15925	COG1819	glycosyl
HUT10_15940	COG0477	Major facilitator Superfamily
HUT10_15945	COG1960	acyl-CoA dehydrogenase activity
HUT10_15950	COG0596	Alpha beta hydrolase
HUT10_15965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_16020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_16025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_16060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HUT10_16090	COG0475	glutathione-regulated potassium exporter activity
HUT10_16135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_16210	COG4977	sequence-specific DNA binding
HUT10_16210	COG1917	Cupin 2, conserved barrel domain protein
HUT10_16215	COG3629	intracellular signal transduction
HUT10_16225	COG4941	Belongs to the sigma-70 factor family
HUT10_16230	COG3795	YCII-related domain
HUT10_16240	COG0009	L-threonylcarbamoyladenylate synthase
HUT10_16250	COG2197	response regulator
HUT10_16260	COG1917	Cupin 2, conserved barrel domain protein
HUT10_16260	COG4977	sequence-specific DNA binding
HUT10_16265	COG2197	response regulator
HUT10_16270	COG4585	Histidine kinase
HUT10_16315	COG1937	Protein conserved in bacteria
HUT10_16355	COG0477	Major facilitator Superfamily
HUT10_16360	COG0587	DNA-directed DNA polymerase activity
HUT10_16370	COG1113	amino acid transport
HUT10_16420	COG1104	cysteine desulfurase activity
HUT10_16430	COG1960	acyl-CoA dehydrogenase activity
HUT10_16460	COG0477	Major facilitator Superfamily
HUT10_16485	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT10_16495	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_16505	COG1620	l-lactate permease
HUT10_16510	COG3201	nicotinamide mononucleotide transporter
HUT10_16525	COG1668	transmembrane transport
HUT10_16530	COG4152	abc transporter atp-binding protein
HUT10_16545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_16575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT10_16595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUT10_16600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUT10_16610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_16610	COG1017	nitric oxide dioxygenase activity
HUT10_16650	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT10_16675	COG0442	prolyl-tRNA aminoacylation
HUT10_16710	COG3022	response to hydroperoxide
HUT10_16715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT10_16725	COG1309	transcriptional regulator
HUT10_16730	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_16735	COG0583	DNA-binding transcription factor activity
HUT10_16775	COG0513	Belongs to the DEAD box helicase family
HUT10_16820	COG2186	Transcriptional regulator
HUT10_16855	COG0456	acetyltransferase
HUT10_16855	COG0454	-acetyltransferase
HUT10_16875	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT10_16880	COG0750	zinc metalloprotease
HUT10_16885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUT10_16895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUT10_16925	COG2814	Major facilitator Superfamily
HUT10_16945	COG3629	intracellular signal transduction
HUT10_16945	COG3903	Transcriptional regulator
HUT10_16965	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_16970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT10_16980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT10_17000	COG4941	Belongs to the sigma-70 factor family
HUT10_17005	COG3795	YCII-related domain
HUT10_17040	COG0789	Transcriptional regulator
HUT10_17090	COG0443	Heat shock 70 kDa protein
HUT10_17095	COG4245	von Willebrand factor, type A
HUT10_17135	COG1674	ftsk spoiiie
HUT10_17180	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_17190	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_17230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT10_17240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUT10_17250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT10_17260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT10_17265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT10_17270	COG1695	Transcriptional regulator
HUT10_17290	COG0233	cytoplasmic translational termination
HUT10_17295	COG0528	UMP kinase activity
HUT10_17300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT10_17305	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT10_17315	COG1191	sigma factor activity
HUT10_17340	COG0792	nuclease activity
HUT10_17350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT10_17355	COG0681	Belongs to the peptidase S26 family
HUT10_17360	COG0335	large ribosomal subunit rRNA binding
HUT10_17365	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT10_17370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT10_17380	COG0228	four-way junction DNA binding
HUT10_17405	COG1132	(ABC) transporter
HUT10_17415	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT10_17425	COG1309	transcriptional regulator
HUT10_17430	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_17435	COG3706	GGDEF domain
HUT10_17440	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT10_17465	COG1595	DNA-templated transcription, initiation
HUT10_17470	COG0583	DNA-binding transcription factor activity
HUT10_17485	COG2873	o-acetylhomoserine
HUT10_17490	COG1832	CoA-binding protein
HUT10_17510	COG1595	DNA-templated transcription, initiation
HUT10_17520	COG4266	Belongs to the allantoicase family
HUT10_17525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT10_17550	COG1309	transcriptional regulator
HUT10_17555	COG3345	alpha-galactosidase
HUT10_17560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_17580	COG3835	regulator
HUT10_17590	COG1301	dicarboxylic acid transport
HUT10_17620	COG1414	Transcriptional regulator
HUT10_17645	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUT10_17650	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_17670	COG1254	Belongs to the acylphosphatase family
HUT10_17695	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT10_17700	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT10_17705	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT10_17715	COG0367	asparagine synthase
HUT10_17725	COG0673	inositol 2-dehydrogenase activity
HUT10_17730	COG1609	Transcriptional regulator
HUT10_17735	COG1082	Xylose isomerase domain protein TIM barrel
HUT10_17755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_17760	COG3718	enzyme involved in inositol metabolism
HUT10_17765	COG3962	Belongs to the TPP enzyme family
HUT10_17790	COG0667	Aldo Keto reductase
HUT10_17800	COG3706	GGDEF domain
HUT10_17845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT10_17850	COG0746	molybdenum cofactor guanylyltransferase activity
HUT10_17855	COG1414	Transcriptional regulator
HUT10_17865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT10_17870	COG3485	protocatechuate 3,4-dioxygenase
HUT10_17875	COG3485	protocatechuate 3,4-dioxygenase
HUT10_17880	COG0183	Belongs to the thiolase family
HUT10_17885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUT10_17890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUT10_17900	COG0395	ABC-type sugar transport system, permease component
HUT10_17910	COG2182	Extracellular solute-binding protein
HUT10_17930	COG1929	Belongs to the glycerate kinase type-1 family
HUT10_17950	COG2149	membrane
HUT10_17975	COG2186	Transcriptional regulator
HUT10_17980	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_17985	COG1129	ABC transporter
HUT10_17995	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_18000	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_18005	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_18010	COG2814	Major facilitator Superfamily
HUT10_18020	COG0789	Transcriptional regulator
HUT10_18050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_18055	COG4122	O-methyltransferase activity
HUT10_18060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT10_18065	COG2186	Transcriptional regulator
HUT10_18075	COG1760	l-serine dehydratase
HUT10_18080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT10_18085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT10_18090	COG0509	glycine decarboxylation via glycine cleavage system
HUT10_18095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT10_18100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT10_18100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT10_18125	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_18130	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT10_18160	COG3386	PFAM SMP-30 Gluconolaconase
HUT10_18180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT10_18190	COG0571	ribonuclease III activity
HUT10_18195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT10_18225	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT10_18230	COG0742	ribosomal rna small subunit methyltransferase
HUT10_18235	COG3973	AAA domain
HUT10_18240	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT10_18240	COG2319	Wd-40 repeat
HUT10_18245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_18255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_18280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT10_18360	COG1404	Belongs to the peptidase S8 family
HUT10_18390	COG1461	Dihydroxyacetone kinase
HUT10_18395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT10_18405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT10_18410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUT10_18450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_18460	COG2205	protein histidine kinase activity
HUT10_18465	COG0745	RESPONSE REGULATOR receiver
HUT10_18505	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT10_18515	COG1920	GTP binding
HUT10_18530	COG3629	intracellular signal transduction
HUT10_18530	COG3903	Transcriptional regulator
HUT10_18540	COG0066	3-isopropylmalate dehydratase activity
HUT10_18545	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT10_18585	COG0419	ATPase involved in DNA repair
HUT10_18590	COG0420	3'-5' exonuclease activity
HUT10_18600	COG0776	regulation of translation
HUT10_18690	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_18695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT10_18700	COG0473	3-isopropylmalate dehydrogenase activity
HUT10_18705	COG1404	Belongs to the peptidase S8 family
HUT10_18745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT10_18750	COG0440	acetolactate synthase activity
HUT10_18765	COG0129	dihydroxy-acid dehydratase activity
HUT10_18785	COG0673	inositol 2-dehydrogenase activity
HUT10_18800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT10_18805	COG0154	amidase activity
HUT10_18810	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT10_18825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT10_18845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_18865	COG0482	sulfurtransferase activity
HUT10_18880	COG2197	response regulator
HUT10_18885	COG0604	alcohol dehydrogenase
HUT10_18900	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT10_18910	COG1307	EDD domain protein, DegV family
HUT10_18920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT10_18930	COG0386	Belongs to the glutathione peroxidase family
HUT10_18945	COG2226	methyltransferase
HUT10_19010	COG0110	maltose O-acetyltransferase activity
HUT10_19020	COG0791	NLP P60 protein
HUT10_19020	COG3883	PFAM NLP P60 protein
HUT10_19030	COG1733	regulation of RNA biosynthetic process
HUT10_19035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_19075	COG2188	Transcriptional regulator
HUT10_19085	COG3979	chitinase
HUT10_19110	COG2226	methyltransferase
HUT10_19115	COG1024	Enoyl-CoA hydratase
HUT10_19120	COG1119	ATPase activity
HUT10_19160	COG0058	SHG alpha-glucan phosphorylase activity
HUT10_19185	COG1846	Transcriptional regulator
HUT10_19195	COG3537	Alpha-1,2-mannosidase
HUT10_19200	COG3537	Alpha-1,2-mannosidase
HUT10_19205	COG1609	Transcriptional regulator
HUT10_19225	COG1879	ABC-type sugar transport system periplasmic component
HUT10_19235	COG3275	phosphorelay sensor kinase activity
HUT10_19240	COG3279	Response regulator of the LytR AlgR family
HUT10_19250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_19260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_19265	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUT10_19270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT10_19275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_19290	COG0183	Belongs to the thiolase family
HUT10_19295	COG0346	lactoylglutathione lyase activity
HUT10_19310	COG0604	alcohol dehydrogenase
HUT10_19325	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_19335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_19340	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT10_19345	COG3396	Phenylacetate-CoA oxygenase
HUT10_19350	COG3460	Phenylacetate-CoA oxygenase
HUT10_19355	COG3396	Phenylacetate-CoA oxygenase
HUT10_19360	COG2030	dehydratase
HUT10_19360	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_19375	COG1309	transcriptional regulator
HUT10_19400	COG2072	flavoprotein involved in K transport
HUT10_19415	COG2183	response to ionizing radiation
HUT10_19435	COG0513	Belongs to the DEAD box helicase family
HUT10_19440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_19465	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUT10_19490	COG1940	carbohydrate kinase activity
HUT10_19495	COG3408	Glycogen debranching enzyme
HUT10_19495	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HUT10_19505	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HUT10_19520	COG3540	Alkaline phosphatase
HUT10_19530	COG3629	intracellular signal transduction
HUT10_19530	COG3903	Transcriptional regulator
HUT10_19535	COG4991	sh3 domain protein
HUT10_19550	COG1879	ABC-type sugar transport system periplasmic component
HUT10_19565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_19570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_19570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_19590	COG1129	ABC transporter
HUT10_19595	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_19600	COG2186	Transcriptional regulator
HUT10_19630	COG1131	(ABC) transporter
HUT10_19650	COG2964	Protein conserved in bacteria
HUT10_19655	COG1126	abc transporter atp-binding protein
HUT10_19660	COG0765	amino acid transport
HUT10_19665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_19700	COG1733	regulation of RNA biosynthetic process
HUT10_19750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT10_19790	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT10_19805	COG1234	tRNA 3'-trailer cleavage
HUT10_19850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_19925	COG0330	HflC and HflK could
HUT10_20000	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_20005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_20010	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_20030	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_20050	COG3848	Pyruvate phosphate dikinase
HUT10_20050	COG0574	Belongs to the PEP-utilizing enzyme family
HUT10_20055	COG1802	Transcriptional regulator
HUT10_20060	COG3848	Pyruvate phosphate dikinase
HUT10_20060	COG0574	Belongs to the PEP-utilizing enzyme family
HUT10_20065	COG0656	L-ascorbic acid biosynthetic process
HUT10_20070	COG0667	Aldo Keto reductase
HUT10_20075	COG2814	Major facilitator Superfamily
HUT10_20080	COG1309	transcriptional regulator
HUT10_20115	COG2080	2 iron, 2 sulfur cluster binding
HUT10_20120	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_20125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_20155	COG0789	Transcriptional regulator
HUT10_20160	COG4221	oxidoreductase activity
HUT10_20175	COG2197	response regulator
HUT10_20185	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_20230	COG0477	Major facilitator Superfamily
HUT10_20245	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_20250	COG0156	8-amino-7-oxononanoate synthase activity
HUT10_20255	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_20265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT10_20275	COG2197	response regulator
HUT10_20300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_20355	COG1131	(ABC) transporter
HUT10_20385	COG1136	(ABC) transporter
HUT10_20415	COG1309	transcriptional regulator
HUT10_20425	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_20445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT10_20460	COG3629	intracellular signal transduction
HUT10_20460	COG3903	Transcriptional regulator
HUT10_20495	COG1846	Transcriptional regulator
HUT10_20500	COG0697	spore germination
HUT10_20590	COG0596	Alpha beta hydrolase
HUT10_20610	COG0596	Alpha beta hydrolase
HUT10_20620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT10_20630	COG1053	succinate dehydrogenase
HUT10_20640	COG1486	melibiose metabolic process
HUT10_20645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_20670	COG1309	transcriptional regulator
HUT10_20680	COG0596	Alpha beta hydrolase
HUT10_20690	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_20705	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_20715	COG2813	Specifically methylates the guanine in position
HUT10_20765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT10_20790	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_20800	COG5640	endopeptidase activity
HUT10_20805	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT10_20810	COG1609	Transcriptional regulator
HUT10_20815	COG1879	ABC-type sugar transport system periplasmic component
HUT10_20820	COG1129	ABC transporter
HUT10_20825	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_20830	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_20870	COG0187	DNA topoisomerase II activity
HUT10_20875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT10_20905	COG0791	NLP P60 protein
HUT10_20905	COG3883	PFAM NLP P60 protein
HUT10_20925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_20930	COG1643	Atp-dependent helicase
HUT10_20935	COG1131	(ABC) transporter
HUT10_20955	COG2197	response regulator
HUT10_20960	COG4585	Histidine kinase
HUT10_20990	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HUT10_20995	COG1228	amidohydrolase
HUT10_21010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT10_21015	COG2986	histidine ammonia-lyase
HUT10_21040	COG3706	GGDEF domain
HUT10_21060	COG4585	Histidine kinase
HUT10_21065	COG2197	response regulator
HUT10_21085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT10_21090	COG2177	Part of the ABC transporter FtsEX involved in
HUT10_21095	COG2884	Cell division ATP-binding protein ftsE
HUT10_21100	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT10_21130	COG1615	UPF0182 protein
HUT10_21160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT10_21200	COG0174	glutamine synthetase
HUT10_21210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT10_21220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT10_21220	COG0519	Catalyzes the synthesis of GMP from XMP
HUT10_21230	COG1522	sequence-specific DNA binding
HUT10_21250	COG0154	amidase activity
HUT10_21255	COG0174	glutamine synthetase
HUT10_21275	COG0653	protein targeting
HUT10_21280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT10_21280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT10_21290	COG1404	Belongs to the peptidase S8 family
HUT10_21300	COG2318	DinB family
HUT10_21315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT10_21325	COG1968	undecaprenyl-diphosphatase activity
HUT10_21330	COG0596	Alpha beta hydrolase
HUT10_21335	COG1309	transcriptional regulator
HUT10_21340	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_21345	COG1177	transmembrane transport
HUT10_21350	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT10_21355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUT10_21360	COG3842	ATPase activity
HUT10_21365	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_21405	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_21415	COG4585	Histidine kinase
HUT10_21535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUT10_21565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT10_21575	COG3265	gluconokinase activity
HUT10_21590	COG0640	Transcriptional regulator
HUT10_21605	COG1486	melibiose metabolic process
HUT10_21610	COG0395	ABC-type sugar transport system, permease component
HUT10_21615	COG1175	transmembrane transport
HUT10_21625	COG1940	carbohydrate kinase activity
HUT10_21635	COG0612	Peptidase, M16
HUT10_21655	COG2321	neutral zinc metallopeptidase
HUT10_21675	COG0714	Associated with various cellular activities
HUT10_21745	COG2378	regulation of single-species biofilm formation
HUT10_21770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT10_21770	COG2146	nitrite reductase [NAD(P)H] activity
HUT10_21775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT10_21775	COG2146	nitrite reductase [NAD(P)H] activity
HUT10_21785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT10_21790	COG0243	molybdopterin cofactor binding
HUT10_21815	COG1309	transcriptional regulator
HUT10_21820	COG2267	carboxylic ester hydrolase activity
HUT10_21840	COG3415	Transposase
HUT10_21840	COG2801	Transposase and inactivated derivatives
HUT10_21860	COG0513	Belongs to the DEAD box helicase family
HUT10_21885	COG2095	MarC family integral membrane protein
HUT10_21890	COG0613	PHP domain protein
HUT10_21920	COG0598	Magnesium transport protein CorA
HUT10_21960	COG4585	Histidine kinase
HUT10_21965	COG2197	response regulator
HUT10_21975	COG1309	transcriptional regulator
HUT10_22030	COG0330	HflC and HflK could
HUT10_22040	COG2239	Acts as a magnesium transporter
HUT10_22055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT10_22060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT10_22070	COG1595	DNA-templated transcription, initiation
HUT10_22075	COG4122	O-methyltransferase activity
HUT10_22080	COG2814	Major facilitator Superfamily
HUT10_22090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT10_22100	COG1024	Enoyl-CoA hydratase
HUT10_22105	COG2818	Glycosylase
HUT10_22130	COG1271	oxidase subunit
HUT10_22135	COG1294	oxidase, subunit
HUT10_22140	COG4988	ABC transporter
HUT10_22145	COG1132	(ABC) transporter
HUT10_22150	COG0463	Glycosyl transferase, family 2
HUT10_22165	COG1611	Belongs to the LOG family
HUT10_22170	COG1073	alpha beta
HUT10_22175	COG1510	regulation of RNA biosynthetic process
HUT10_22180	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_22280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT10_22285	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT10_22285	COG0778	Nitroreductase
HUT10_22300	COG1725	Transcriptional regulator
HUT10_22335	COG0438	transferase activity, transferring glycosyl groups
HUT10_22360	COG1309	transcriptional regulator
HUT10_22375	COG1316	TRANSCRIPTIONal
HUT10_22380	COG1316	TRANSCRIPTIONal
HUT10_22420	COG1073	alpha beta
HUT10_22435	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_22495	COG2197	response regulator
HUT10_22500	COG2197	response regulator
HUT10_22505	COG2205	protein histidine kinase activity
HUT10_22515	COG0483	inositol monophosphate 1-phosphatase activity
HUT10_22545	COG0791	NLP P60 protein
HUT10_22545	COG3103	Sh3 type 3 domain protein
HUT10_22545	COG1388	LysM domain
HUT10_22560	COG2197	response regulator
HUT10_22565	COG4585	Histidine kinase
HUT10_22590	COG1595	DNA-templated transcription, initiation
HUT10_22615	COG0583	DNA-binding transcription factor activity
HUT10_22635	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_22645	COG1733	regulation of RNA biosynthetic process
HUT10_22655	COG1309	transcriptional regulator
HUT10_22660	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUT10_22675	COG4585	Histidine kinase
HUT10_22685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_22695	COG1846	Transcriptional regulator
HUT10_22700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_22725	COG0424	maF-like protein
HUT10_22730	COG1301	dicarboxylic acid transport
HUT10_22745	COG4770	biotin carboxylase activity
HUT10_22765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT10_22770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT10_22775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT10_22815	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_22815	COG1473	amidohydrolase
HUT10_22840	COG0515	serine threonine protein kinase
HUT10_22870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT10_22895	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_22910	COG2205	protein histidine kinase activity
HUT10_22915	COG0745	RESPONSE REGULATOR receiver
HUT10_22920	COG0475	glutathione-regulated potassium exporter activity
HUT10_22940	COG0667	Aldo Keto reductase
HUT10_22945	COG0789	Transcriptional regulator
HUT10_22980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUT10_22985	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_22990	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_23035	COG0395	ABC-type sugar transport system, permease component
HUT10_23050	COG1063	alcohol dehydrogenase
HUT10_23080	COG1733	regulation of RNA biosynthetic process
HUT10_23105	COG2271	Major facilitator Superfamily
HUT10_23110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT10_23150	COG3345	alpha-galactosidase
HUT10_23155	COG2009	succinate dehydrogenase
HUT10_23170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT10_23190	COG1295	ribonuclease BN
HUT10_23200	COG0180	Tryptophanyl-tRNA synthetase
HUT10_23250	COG2226	methyltransferase
HUT10_23280	COG3415	Transposase
HUT10_23280	COG2801	Transposase and inactivated derivatives
HUT10_23285	COG2814	Major facilitator Superfamily
HUT10_23290	COG0640	Transcriptional regulator
HUT10_23295	COG2814	Major facilitator Superfamily
HUT10_23305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT10_23330	COG0587	DNA-directed DNA polymerase activity
HUT10_23360	COG0138	bifunctional purine biosynthesis protein purh
HUT10_23385	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT10_23405	COG3415	Transposase
HUT10_23405	COG2801	Transposase and inactivated derivatives
HUT10_23440	COG2815	serine threonine protein kinase
HUT10_23440	COG0515	serine threonine protein kinase
HUT10_23445	COG0515	serine threonine protein kinase
HUT10_23445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT10_23450	COG0583	DNA-binding transcription factor activity
HUT10_23480	COG0519	Catalyzes the synthesis of GMP from XMP
HUT10_23480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT10_23495	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_23500	COG0277	FAD linked oxidase domain protein
HUT10_23520	COG0516	GMP reductase activity
HUT10_23585	COG0459	protein refolding
HUT10_23590	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT10_23600	COG1215	transferase activity, transferring glycosyl groups
HUT10_23620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUT10_23625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT10_23630	COG0456	acetyltransferase
HUT10_23640	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_23645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUT10_23645	COG0825	malonyl-CoA metabolic process
HUT10_23655	COG0802	atpase or kinase
HUT10_23665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT10_23670	COG3842	ATPase activity
HUT10_23675	COG1070	Carbohydrate kinase
HUT10_23680	COG1349	DNA-binding transcription factor activity
HUT10_23720	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_23730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT10_23735	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT10_23740	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT10_23770	COG0443	Heat shock 70 kDa protein
HUT10_23775	COG1674	ftsk spoiiie
HUT10_23785	COG1404	Belongs to the peptidase S8 family
HUT10_23820	COG0101	tRNA pseudouridine synthase activity
HUT10_23825	COG0203	ribosomal protein L17
HUT10_23830	COG0202	RNA polymerase activity
HUT10_23835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT10_23840	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT10_23855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT10_23860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT10_23870	COG0563	adenylate kinase activity
HUT10_23880	COG1280	lysine exporter protein (LysE YggA)
HUT10_23890	COG0200	Binds to the 23S rRNA
HUT10_23895	COG1841	ribosomal large subunit assembly
HUT10_23900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT10_23905	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT10_23910	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT10_23915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT10_23925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT10_23930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT10_23935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT10_23940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT10_23945	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT10_23950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT10_23955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT10_23960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT10_23965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT10_23970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT10_23975	COG0089	rRNA binding
HUT10_23980	COG0088	Forms part of the polypeptide exit tunnel
HUT10_23985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT10_23990	COG0051	transcription antitermination factor activity, RNA binding
HUT10_24000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT10_24005	COG0049	tRNA binding
HUT10_24010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUT10_24075	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT10_24085	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT10_24100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT10_24110	COG3958	Transketolase
HUT10_24115	COG3959	Transketolase, thiamine diphosphate binding domain
HUT10_24125	COG2124	cytochrome p450
HUT10_24140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_24150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_24165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT10_24185	COG2124	cytochrome p450
HUT10_24190	COG2124	cytochrome p450
HUT10_24210	COG0477	Major facilitator Superfamily
HUT10_24220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_24230	COG0546	phosphoglycolate phosphatase activity
HUT10_24245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT10_24250	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT10_24315	COG0673	inositol 2-dehydrogenase activity
HUT10_24335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT10_24360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_24375	COG0222	ribosome binding
HUT10_24395	COG0081	regulation of translation
HUT10_24425	COG1725	Transcriptional regulator
HUT10_24445	COG2030	dehydratase
HUT10_24450	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT10_24495	COG1666	GTP binding
HUT10_24520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_24535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT10_24550	COG4310	Domain of unknown function (DUF2172)
HUT10_24560	COG1215	transferase activity, transferring glycosyl groups
HUT10_24570	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUT10_24575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT10_24620	COG0367	asparagine synthase
HUT10_24640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT10_24655	COG1834	amidinotransferase
HUT10_24660	COG1522	sequence-specific DNA binding
HUT10_24680	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT10_24680	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT10_24685	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT10_24730	COG1007	ATP synthesis coupled electron transport
HUT10_24740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT10_24745	COG0713	ATP synthesis coupled electron transport
HUT10_24750	COG0839	Belongs to the complex I subunit 6 family
HUT10_24755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT10_24760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT10_24765	COG1034	ATP synthesis coupled electron transport
HUT10_24770	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT10_24780	COG0649	NAD binding
HUT10_24785	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT10_24790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT10_24805	COG2226	methyltransferase
HUT10_24810	COG0438	transferase activity, transferring glycosyl groups
HUT10_24835	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HUT10_24840	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HUT10_24870	COG1522	sequence-specific DNA binding
HUT10_24890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUT10_24900	COG0785	Cytochrome C biogenesis protein
HUT10_24915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT10_24920	COG0406	alpha-ribazole phosphatase activity
HUT10_24925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT10_24940	COG0577	efflux transmembrane transporter activity
HUT10_24940	COG1136	(ABC) transporter
HUT10_24945	COG1136	(ABC) transporter
HUT10_24945	COG0577	efflux transmembrane transporter activity
HUT10_24950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT10_24985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT10_24985	COG1648	precorrin-2 dehydrogenase activity
HUT10_24990	COG0181	hydroxymethylbilane synthase activity
HUT10_24995	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT10_25000	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUT10_25015	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_25020	COG1595	DNA-templated transcription, initiation
HUT10_25060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUT10_25090	COG5002	protein histidine kinase activity
HUT10_25095	COG0667	Aldo Keto reductase
HUT10_25110	COG0588	phosphoglycerate mutase activity
HUT10_25125	COG0438	transferase activity, transferring glycosyl groups
HUT10_25140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT10_25170	COG1064	alcohol dehydrogenase
HUT10_25175	COG1309	transcriptional regulator
HUT10_25185	COG0640	Transcriptional regulator
HUT10_25195	COG2130	NADP-dependent
HUT10_25220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_25235	COG1846	Transcriptional regulator
HUT10_25250	COG1174	glycine betaine transport
HUT10_25270	COG2986	histidine ammonia-lyase
HUT10_25300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT10_25305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT10_25325	COG2733	membrane
HUT10_25340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_25345	COG2364	Membrane
HUT10_25370	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUT10_25460	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUT10_25485	COG1414	Transcriptional regulator
HUT10_25500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT10_25505	COG2233	PERMEase
HUT10_25550	COG2226	methyltransferase
HUT10_25605	COG2188	Transcriptional regulator
HUT10_25650	COG1278	Cold shock
HUT10_25665	COG1595	DNA-templated transcription, initiation
HUT10_25685	COG0515	serine threonine protein kinase
HUT10_25690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_25705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUT10_25710	COG3199	ATP-NAD kinase
HUT10_25715	COG2217	Heavy metal translocating P-type atpase
HUT10_25730	COG0028	Belongs to the TPP enzyme family
HUT10_25745	COG0515	serine threonine protein kinase
HUT10_25795	COG2318	DinB family
HUT10_25805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT10_25820	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT10_25835	COG1846	Transcriptional regulator
HUT10_25855	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT10_25855	COG1902	pentaerythritol trinitrate reductase activity
HUT10_25860	COG0287	Prephenate dehydrogenase
HUT10_25915	COG1131	(ABC) transporter
HUT10_25920	COG3559	Exporter of polyketide antibiotics
HUT10_25985	COG0667	Aldo Keto reductase
HUT10_25995	COG3584	3D domain protein
HUT10_25995	COG3583	domain protein
HUT10_26025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUT10_26030	COG3469	chitinase activity
HUT10_26060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_26070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT10_26100	COG2186	Transcriptional regulator
HUT10_26105	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_26120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_26125	COG1522	sequence-specific DNA binding
HUT10_26140	COG1672	PFAM Archaeal ATPase
HUT10_26140	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_26165	COG1116	anion transmembrane transporter activity
HUT10_26170	COG3290	protein histidine kinase activity
HUT10_26175	COG4565	transcriptional regulatory protein
HUT10_26235	COG2234	aminopeptidase activity
HUT10_26240	COG1063	alcohol dehydrogenase
HUT10_26265	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HUT10_26275	COG2089	acid synthase
HUT10_26290	COG1216	Glycosyl transferase, family 2
HUT10_26320	COG1216	Glycosyl transferase, family 2
HUT10_26330	COG0277	FAD linked oxidase domain protein
HUT10_26335	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_26350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT10_26370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_26375	COG0561	phosphatase activity
HUT10_26410	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_26425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUT10_26440	COG3293	Transposase
HUT10_26460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUT10_26465	COG0438	transferase activity, transferring glycosyl groups
HUT10_26495	COG0579	oxidoreductase
HUT10_26505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT10_26510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT10_26525	COG0596	Alpha beta hydrolase
HUT10_26535	COG0754	glutathionylspermidine amidase activity
HUT10_26570	COG0406	alpha-ribazole phosphatase activity
HUT10_26580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUT10_26585	COG1072	(Pantothenic acid kinase))
HUT10_26600	COG4715	Zinc finger, swim domain protein
HUT10_26665	COG4988	ABC transporter
HUT10_26670	COG1294	oxidase, subunit
HUT10_26675	COG1271	oxidase subunit
HUT10_26715	COG2319	Wd-40 repeat
HUT10_26715	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT10_26790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_26815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_26840	COG3275	phosphorelay sensor kinase activity
HUT10_26845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT10_26890	COG0438	transferase activity, transferring glycosyl groups
HUT10_26890	COG1216	Glycosyl transferase, family 2
HUT10_26915	COG2197	response regulator
HUT10_26920	COG4585	Histidine kinase
HUT10_26930	COG0477	Major facilitator Superfamily
HUT10_26955	COG0405	Gamma-glutamyltransferase
HUT10_26965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT10_26975	COG2226	methyltransferase
HUT10_27000	COG1174	glycine betaine transport
HUT10_27010	COG1174	glycine betaine transport
HUT10_27025	COG2372	response to copper ion
HUT10_27025	COG1276	copper resistance
HUT10_27055	COG2211	Major facilitator Superfamily
HUT10_27065	COG1309	transcriptional regulator
HUT10_27085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT10_27090	COG0702	epimerase
HUT10_27100	COG2301	Belongs to the HpcH HpaI aldolase family
HUT10_27120	COG0154	amidase activity
HUT10_27125	COG4608	Belongs to the ABC transporter superfamily
HUT10_27130	COG0444	Belongs to the ABC transporter superfamily
HUT10_27145	COG0747	negative chemotaxis
HUT10_27150	COG2186	Transcriptional regulator
HUT10_27180	COG0626	cystathionine gamma-synthase activity
HUT10_27210	COG1716	ATPase activity
HUT10_27215	COG1716	ATPase activity
HUT10_27230	COG0768	penicillin binding
HUT10_27235	COG0515	serine threonine protein kinase
HUT10_27240	COG0515	serine threonine protein kinase
HUT10_27240	COG2815	serine threonine protein kinase
HUT10_27270	COG2197	response regulator
HUT10_27305	COG3764	Sortase (surface protein transpeptidase)
HUT10_27320	COG0457	Tetratricopeptide repeat
HUT10_27320	COG0705	Rhomboid family
HUT10_27360	COG0321	lipoyl(octanoyl) transferase activity
HUT10_27415	COG0640	Transcriptional regulator
HUT10_27450	COG0187	DNA topoisomerase II activity
HUT10_27455	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT10_27460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT10_27465	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT10_27470	COG0592	DNA-directed DNA polymerase activity
HUT10_27485	COG0594	ribonuclease P activity
HUT10_27490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUT10_27495	COG0706	membrane insertase activity
HUT10_27505	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT10_27510	COG1192	Involved in chromosome partitioning
HUT10_27520	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT10_27535	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUT10_27535	COG3409	Peptidoglycan-binding domain 1 protein
HUT10_27540	COG0492	ferredoxin-NADP+ reductase activity
HUT10_27540	COG3118	belongs to the thioredoxin family
HUT10_27555	COG1595	DNA-templated transcription, initiation
HUT10_27585	COG0617	tRNA 3'-terminal CCA addition
HUT10_27665	COG0495	leucyl-tRNA aminoacylation
HUT10_27670	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_27725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_27735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT10_27740	COG0477	Major facilitator Superfamily
HUT10_27755	COG2197	response regulator
HUT10_27780	COG3384	dioxygenase
HUT10_27820	COG0359	binds to the 23S rRNA
HUT10_27825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT10_27835	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT10_27865	COG1940	carbohydrate kinase activity
HUT10_27870	COG0673	inositol 2-dehydrogenase activity
HUT10_27875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT10_27880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT10_27890	COG1695	Transcriptional regulator
HUT10_27900	COG1595	DNA-templated transcription, initiation
HUT10_27910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT10_27915	COG1846	Transcriptional regulator
HUT10_27920	COG2814	Major facilitator Superfamily
HUT10_27935	COG4221	oxidoreductase activity
HUT10_27940	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_27945	COG2197	response regulator
HUT10_27955	COG1136	(ABC) transporter
HUT10_27965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUT10_27980	COG1131	(ABC) transporter
HUT10_28000	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_28005	COG2197	response regulator
HUT10_28010	COG4585	Histidine kinase
HUT10_28035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT10_28050	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUT10_28065	COG1131	(ABC) transporter
HUT10_28135	COG0183	Belongs to the thiolase family
HUT10_28140	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_28145	COG2030	dehydratase
HUT10_28150	COG1309	transcriptional regulator
HUT10_28185	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUT10_28210	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_28215	COG0022	dehydrogenase e1 component
HUT10_28225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT10_28240	COG1305	Transglutaminase-like
HUT10_28285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT10_28305	COG0477	Major facilitator Superfamily
HUT10_28315	COG1960	acyl-CoA dehydrogenase activity
HUT10_28320	COG2197	response regulator
HUT10_28325	COG3663	DNA glycosylase
HUT10_28365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_28380	COG3795	YCII-related domain
HUT10_28385	COG4941	Belongs to the sigma-70 factor family
HUT10_28405	COG0546	phosphoglycolate phosphatase activity
HUT10_28485	COG2340	Cysteine-rich secretory protein family
HUT10_28500	COG0247	lactate metabolic process
HUT10_28500	COG2181	nitrate reductase activity
HUT10_28545	COG0443	Heat shock 70 kDa protein
HUT10_28550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT10_28555	COG0484	heat shock protein binding
HUT10_28560	COG0789	Transcriptional regulator
HUT10_28575	COG0412	Dienelactone hydrolase
HUT10_28580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_28580	COG1017	nitric oxide dioxygenase activity
HUT10_28600	COG0542	response to heat
HUT10_28615	COG0300	oxidoreductase activity
HUT10_28620	COG1136	(ABC) transporter
HUT10_28635	COG1595	DNA-templated transcription, initiation
HUT10_28665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT10_28675	COG0243	molybdopterin cofactor binding
HUT10_28690	COG1609	Transcriptional regulator
HUT10_28715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_28720	COG0572	uridine kinase
HUT10_28725	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_28740	COG0586	Pfam SNARE associated Golgi protein
HUT10_28750	COG0477	Major facilitator Superfamily
HUT10_28760	COG3467	pyridoxamine 5'-phosphate
HUT10_28765	COG0277	FAD linked oxidase domain protein
HUT10_28770	COG0586	Pfam SNARE associated Golgi protein
HUT10_28815	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_28820	COG0667	Aldo Keto reductase
HUT10_28875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_28905	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT10_28920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_28925	COG0025	NhaP-type Na H and K H
HUT10_28930	COG2814	Major facilitator Superfamily
HUT10_28945	COG0584	glycerophosphoryl diester phosphodiesterase
HUT10_28990	COG0436	Aminotransferase
HUT10_29050	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_29055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT10_29065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_29075	COG0765	amino acid transport
HUT10_29080	COG1126	abc transporter atp-binding protein
HUT10_29095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT10_29145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT10_29150	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT10_29160	COG1132	(ABC) transporter
HUT10_29170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT10_29175	COG2197	response regulator
HUT10_29180	COG4585	Histidine kinase
HUT10_29245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT10_29280	COG3845	ABC transporter
HUT10_29330	COG1984	allophanate hydrolase subunit 2
HUT10_29335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUT10_29340	COG4044	May play a role in the intracellular transport of hydrophobic ligands
HUT10_29370	COG0745	RESPONSE REGULATOR receiver
HUT10_29380	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT10_29395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT10_29405	COG1316	TRANSCRIPTIONal
HUT10_29410	COG3706	GGDEF domain
HUT10_29415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT10_29420	COG0596	Alpha beta hydrolase
HUT10_29440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_29445	COG1397	ADP-ribosylglycohydrolase
HUT10_29450	COG2188	Transcriptional regulator
HUT10_29475	COG0673	inositol 2-dehydrogenase activity
HUT10_29510	COG3973	AAA domain
HUT10_29520	COG0531	amino acid
HUT10_29540	COG1802	Transcriptional regulator
HUT10_29555	COG1175	transmembrane transport
HUT10_29560	COG0395	ABC-type sugar transport system, permease component
HUT10_29565	COG0789	Transcriptional regulator
HUT10_29575	COG4702	Belongs to the UPF0303 family
HUT10_29590	COG1473	amidohydrolase
HUT10_29630	COG2175	clavaminate synthase activity
HUT10_29635	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
HUT10_29680	COG1674	ftsk spoiiie
HUT10_29725	COG5479	isomerase activity
HUT10_29725	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT10_29735	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_29755	COG2197	response regulator
HUT10_29770	COG0745	RESPONSE REGULATOR receiver
HUT10_29775	COG2205	protein histidine kinase activity
HUT10_29780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_29790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_29795	COG1116	anion transmembrane transporter activity
HUT10_29845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT10_29850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUT10_29855	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUT10_29865	COG1215	transferase activity, transferring glycosyl groups
HUT10_29885	COG1216	Glycosyl transferase, family 2
HUT10_29900	COG0747	negative chemotaxis
HUT10_29915	COG0444	Belongs to the ABC transporter superfamily
HUT10_29920	COG4608	Belongs to the ABC transporter superfamily
HUT10_29925	COG4941	Belongs to the sigma-70 factor family
HUT10_29930	COG3795	YCII-related domain
HUT10_29950	COG0697	spore germination
HUT10_29955	COG0583	DNA-binding transcription factor activity
HUT10_30010	COG1690	Belongs to the RtcB family
HUT10_30025	COG2814	Major facilitator Superfamily
HUT10_30050	COG1764	response to oxidative stress
HUT10_30055	COG0783	Belongs to the Dps family
HUT10_30060	COG0076	glutamate decarboxylase activity
HUT10_30070	COG1902	pentaerythritol trinitrate reductase activity
HUT10_30100	COG1408	metallophosphoesterase
HUT10_30110	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUT10_30160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_30175	COG0592	DNA-directed DNA polymerase activity
HUT10_30225	COG0596	Alpha beta hydrolase
HUT10_30235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT10_30240	COG3104	oligopeptide transport
HUT10_30265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_30275	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HUT10_30285	COG0640	Transcriptional regulator
HUT10_30290	COG2814	Major facilitator Superfamily
HUT10_30295	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HUT10_30300	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUT10_30305	COG1737	Transcriptional regulator
HUT10_30310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT10_30315	COG3876	Protein conserved in bacteria
HUT10_30320	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_30375	COG1111	helicase
HUT10_30375	COG1205	dead DEAH box helicase
HUT10_30380	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT10_30400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT10_30400	COG1754	DNA topoisomerase type I activity
HUT10_30430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT10_30435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUT10_30510	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT10_30515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT10_30520	COG0483	inositol monophosphate 1-phosphatase activity
HUT10_30535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT10_30540	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT10_30550	COG0037	tRNA processing
HUT10_30580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT10_30590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUT10_30605	COG0789	Transcriptional regulator
HUT10_30630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT10_30635	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT10_30640	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT10_30655	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT10_30685	COG0443	Heat shock 70 kDa protein
HUT10_30710	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUT10_30750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT10_30775	COG1194	a g-specific adenine glycosylase
HUT10_30790	COG1609	Transcriptional regulator
HUT10_30795	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUT10_30800	COG1120	ATPase activity
HUT10_30805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT10_30815	COG4399	Belongs to the UPF0754 family
HUT10_30830	COG0235	Class ii aldolase
HUT10_30875	COG0215	cysteine-tRNA ligase activity
HUT10_30890	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT10_30895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT10_30900	COG1329	Transcriptional regulator
HUT10_30905	COG2847	Copper chaperone PCu(A)C
HUT10_30910	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUT10_30950	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUT10_30985	COG2255	four-way junction helicase activity
HUT10_31020	COG0789	Transcriptional regulator
HUT10_31055	COG1595	DNA-templated transcription, initiation
HUT10_31095	COG0642	Histidine kinase
HUT10_31115	COG3795	YCII-related domain
HUT10_31120	COG3795	YCII-related domain
HUT10_31125	COG4941	Belongs to the sigma-70 factor family
HUT10_31135	COG1620	l-lactate permease
HUT10_31155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT10_31160	COG1492	cobalamin metabolic process
HUT10_31170	COG0745	RESPONSE REGULATOR receiver
HUT10_31215	COG1832	CoA-binding protein
HUT10_31225	COG0346	lactoylglutathione lyase activity
HUT10_31240	COG1132	(ABC) transporter
HUT10_31325	COG5416	Lipopolysaccharide assembly protein A domain
HUT10_31340	COG4399	Belongs to the UPF0754 family
HUT10_31345	COG1733	regulation of RNA biosynthetic process
HUT10_31355	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUT10_31370	COG1917	Cupin 2, conserved barrel domain protein
HUT10_31375	COG5285	phytanoyl-CoA dioxygenase
HUT10_31380	COG3629	intracellular signal transduction
HUT10_31380	COG3903	Transcriptional regulator
HUT10_31410	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUT10_31420	COG2971	BadF BadG BcrA BcrD
HUT10_31425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT10_31435	COG0477	Major facilitator Superfamily
HUT10_31440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT10_31450	COG0352	thiamine-phosphate diphosphorylase activity
HUT10_31455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT10_31455	COG2022	thiamine diphosphate biosynthetic process
HUT10_31465	COG2022	thiamine diphosphate biosynthetic process
HUT10_31490	COG0604	alcohol dehydrogenase
HUT10_31495	COG1733	regulation of RNA biosynthetic process
HUT10_31510	COG0351	phosphomethylpyrimidine kinase
HUT10_31515	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT10_31520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT10_31530	COG0242	peptide deformylase activity
HUT10_31545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT10_31555	COG0688	phosphatidylethanolamine metabolic process
HUT10_31565	COG2261	transglycosylase associated protein
HUT10_31595	COG1278	Cold shock
HUT10_31610	COG0459	protein refolding
HUT10_31630	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_31635	COG3629	intracellular signal transduction
HUT10_31635	COG3903	Transcriptional regulator
HUT10_31655	COG1061	Type III restriction enzyme res subunit
HUT10_31710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT10_31710	COG1116	anion transmembrane transporter activity
HUT10_31715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_31730	COG0642	Histidine kinase
HUT10_31735	COG2018	Roadblock/LC7 domain
HUT10_31750	COG2018	Roadblock/LC7 domain
HUT10_31795	COG1388	LysM domain
HUT10_31805	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT10_31810	COG1846	Transcriptional regulator
HUT10_31845	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT10_31850	COG3304	Inner membrane component domain
HUT10_31855	COG0384	phenazine biosynthesis protein PhzF
HUT10_31880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT10_31900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT10_31915	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_31925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT10_31930	COG1309	transcriptional regulator
HUT10_31935	COG0546	phosphoglycolate phosphatase activity
HUT10_31945	COG1278	Cold shock
HUT10_31955	COG2814	Major facilitator Superfamily
HUT10_31980	COG2252	PERMEase
HUT10_31995	COG2814	Major facilitator Superfamily
HUT10_32000	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HUT10_32010	COG5398	heme oxygenase
HUT10_32025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT10_32045	COG2205	protein histidine kinase activity
HUT10_32050	COG0745	RESPONSE REGULATOR receiver
HUT10_32065	COG0577	efflux transmembrane transporter activity
HUT10_32065	COG1136	(ABC) transporter
HUT10_32070	COG1136	(ABC) transporter
HUT10_32070	COG0577	efflux transmembrane transporter activity
HUT10_32075	COG1228	amidohydrolase
HUT10_32080	COG5650	phosphatidylinositol metabolic process
HUT10_32100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT10_32105	COG2197	response regulator
HUT10_32120	COG1131	(ABC) transporter
HUT10_32140	COG0831	urea catabolic process
HUT10_32145	COG0832	Belongs to the urease beta subunit family
HUT10_32150	COG0804	urea catabolic process
HUT10_32160	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT10_32165	COG0829	nickel cation binding
HUT10_32185	COG0259	pyridoxamine-phosphate oxidase activity
HUT10_32210	COG1309	transcriptional regulator
HUT10_32215	COG2017	converts alpha-aldose to the beta-anomer
HUT10_32225	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT10_32240	COG1960	acyl-CoA dehydrogenase activity
HUT10_32260	COG0415	Belongs to the DNA photolyase family
HUT10_32270	COG4152	abc transporter atp-binding protein
HUT10_32295	COG0277	FAD linked oxidase domain protein
HUT10_32315	COG1595	DNA-templated transcription, initiation
HUT10_32345	COG0395	ABC-type sugar transport system, permease component
HUT10_32350	COG1175	transmembrane transport
HUT10_32355	COG2182	Extracellular solute-binding protein
HUT10_32370	COG1169	isochorismate synthase
HUT10_32405	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_32410	COG1024	Enoyl-CoA hydratase
HUT10_32430	COG1321	iron dependent repressor
HUT10_32465	COG1984	allophanate hydrolase subunit 2
HUT10_32480	COG4336	lyase activity
HUT10_32485	COG2814	Major facilitator Superfamily
HUT10_32495	COG3469	chitinase activity
HUT10_32525	COG0747	negative chemotaxis
HUT10_32535	COG0601	transmembrane transport
HUT10_32540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT10_32545	COG0444	Belongs to the ABC transporter superfamily
HUT10_32560	COG1960	acyl-CoA dehydrogenase activity
HUT10_32605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT10_32605	COG2755	lipolytic protein G-D-S-L family
HUT10_32615	COG0583	DNA-binding transcription factor activity
HUT10_32625	COG3285	dna ligase
HUT10_32625	COG1793	dna ligase
HUT10_32645	COG0438	transferase activity, transferring glycosyl groups
HUT10_32660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_32670	COG0483	inositol monophosphate 1-phosphatase activity
HUT10_32675	COG0515	serine threonine protein kinase
HUT10_32675	COG2815	serine threonine protein kinase
HUT10_32680	COG0438	transferase activity, transferring glycosyl groups
HUT10_32700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_32705	COG0667	Aldo Keto reductase
HUT10_32760	COG2197	response regulator
HUT10_32765	COG2860	membrane
HUT10_32770	COG0745	RESPONSE REGULATOR receiver
HUT10_32785	COG1349	DNA-binding transcription factor activity
HUT10_32800	COG2801	Transposase and inactivated derivatives
HUT10_32835	COG0745	RESPONSE REGULATOR receiver
HUT10_32840	COG5002	protein histidine kinase activity
HUT10_32845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT10_32850	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT10_32850	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT10_32880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT10_32885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT10_32895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_32995	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT10_33000	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT10_33005	COG2205	protein histidine kinase activity
HUT10_33010	COG0745	RESPONSE REGULATOR receiver
HUT10_33025	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT10_33035	COG2124	cytochrome p450
HUT10_33040	COG5001	Diguanylate cyclase
HUT10_33045	COG0697	spore germination
HUT10_33085	COG1595	DNA-templated transcription, initiation
HUT10_33095	COG3284	Transcriptional regulator
HUT10_33110	COG2258	MOSC domain
HUT10_33145	COG0515	serine threonine protein kinase
HUT10_33150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT10_33185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT10_33210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT10_33215	COG0084	hydrolase, TatD family'
HUT10_33225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT10_33230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT10_33235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT10_33240	COG0488	(ABC) transporter
HUT10_33245	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_33255	COG3599	regulation of cell shape
HUT10_33260	COG0193	aminoacyl-tRNA hydrolase activity
HUT10_33290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT10_33320	COG1051	belongs to the nudix hydrolase family
HUT10_33325	COG0494	nUDIX hydrolase
HUT10_33345	COG2133	pyrroloquinoline quinone binding
HUT10_33350	COG2197	response regulator
HUT10_33355	COG4585	Histidine kinase
HUT10_33365	COG0586	Pfam SNARE associated Golgi protein
HUT10_33410	COG1595	DNA-templated transcription, initiation
HUT10_33455	COG2837	iron assimilation
HUT10_33465	COG0672	)-iron permease
HUT10_33485	COG0148	phosphopyruvate hydratase activity
HUT10_33510	COG4166	transmembrane transport
HUT10_33525	COG0444	Belongs to the ABC transporter superfamily
HUT10_33530	COG4608	Belongs to the ABC transporter superfamily
HUT10_33560	COG1515	deoxyribonuclease V activity
HUT10_33575	COG3979	chitinase
HUT10_33625	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HUT10_33635	COG2198	Histidine kinase
HUT10_33635	COG2205	protein histidine kinase activity
HUT10_33635	COG0784	Response regulator, receiver
HUT10_33705	COG3903	Transcriptional regulator
HUT10_33705	COG3629	intracellular signal transduction
HUT10_33725	COG1132	(ABC) transporter
HUT10_33735	COG0148	phosphopyruvate hydratase activity
HUT10_33740	COG2205	protein histidine kinase activity
HUT10_33755	COG5297	Belongs to the glycosyl hydrolase family 6
HUT10_33805	COG0477	Major facilitator Superfamily
HUT10_33815	COG0667	Aldo Keto reductase
HUT10_33820	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_33825	COG2197	response regulator
HUT10_33835	COG1175	transmembrane transport
HUT10_33845	COG2723	6-phospho-beta-galactosidase activity
HUT10_33850	COG3903	Transcriptional regulator
HUT10_33850	COG3629	intracellular signal transduction
HUT10_33915	COG2391	methyltransferase activity
HUT10_33920	COG0183	Belongs to the thiolase family
HUT10_33965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT10_33995	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT10_34005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_34010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT10_34020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_34030	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT10_34035	COG2226	methyltransferase
HUT10_34045	COG1331	Highly conserved protein containing a thioredoxin domain
HUT10_34070	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
HUT10_34095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT10_34115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_34140	COG1793	dna ligase
HUT10_34150	COG0114	fumarate hydratase activity
HUT10_34155	COG1073	alpha beta
HUT10_34165	COG0492	ferredoxin-NADP+ reductase activity
HUT10_34180	COG1722	exodeoxyribonuclease VII activity
HUT10_34190	COG1570	exodeoxyribonuclease VII activity
HUT10_34200	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT10_34225	COG0419	ATPase involved in DNA repair
HUT10_34240	COG0012	GTP binding
HUT10_34280	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT10_34295	COG3842	ATPase activity
HUT10_34310	COG1131	(ABC) transporter
HUT10_34320	COG0745	RESPONSE REGULATOR receiver
HUT10_34325	COG2205	protein histidine kinase activity
HUT10_34335	COG0180	Tryptophanyl-tRNA synthetase
HUT10_34355	COG0747	negative chemotaxis
HUT10_34365	COG0601	transmembrane transport
HUT10_34380	COG1733	regulation of RNA biosynthetic process
HUT10_34385	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_34395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_34440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT10_34445	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT10_34455	COG1482	cell wall glycoprotein biosynthetic process
HUT10_34460	COG3903	Transcriptional regulator
HUT10_34460	COG3629	intracellular signal transduction
HUT10_34470	COG0531	amino acid
HUT10_34535	COG1414	Transcriptional regulator
HUT10_34545	COG0745	RESPONSE REGULATOR receiver
HUT10_34550	COG5000	phosphorelay sensor kinase activity
HUT10_34550	COG5002	protein histidine kinase activity
HUT10_34565	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT10_34570	COG0653	protein targeting
HUT10_34585	COG1011	Hydrolase
HUT10_34590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT10_34620	COG1162	GTPase activity
HUT10_34625	COG2135	peptidase activity
HUT10_34645	COG1595	DNA-templated transcription, initiation
HUT10_34665	COG1597	lipid kinase activity
HUT10_34680	COG0406	alpha-ribazole phosphatase activity
HUT10_34695	COG1846	Transcriptional regulator
HUT10_34705	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUT10_34720	COG1125	glycine betaine transport
HUT10_34720	COG0517	IMP dehydrogenase activity
HUT10_34725	COG1174	glycine betaine transport
HUT10_34730	COG1174	glycine betaine transport
HUT10_34755	COG4221	oxidoreductase activity
HUT10_34765	COG1280	lysine exporter protein (LysE YggA)
HUT10_34770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_34785	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_34785	COG0567	Dehydrogenase, E1 component
HUT10_34805	COG1132	(ABC) transporter
HUT10_34820	COG0745	RESPONSE REGULATOR receiver
HUT10_34825	COG0686	Belongs to the AlaDH PNT family
HUT10_34845	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HUT10_34845	COG2508	Transcriptional regulator
HUT10_34850	COG2226	methyltransferase
HUT10_34885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT10_34895	COG1309	transcriptional regulator
HUT10_34900	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT10_34910	COG2755	lipolytic protein G-D-S-L family
HUT10_34915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_34925	COG1960	acyl-CoA dehydrogenase activity
HUT10_34960	COG4221	oxidoreductase activity
HUT10_35030	COG4974	Belongs to the 'phage' integrase family
HUT10_35035	COG1960	acyl-CoA dehydrogenase activity
HUT10_35040	COG1960	acyl-CoA dehydrogenase activity
HUT10_35105	COG1309	transcriptional regulator
HUT10_35110	COG0183	Belongs to the thiolase family
HUT10_35115	COG1024	Enoyl-CoA hydratase
HUT10_35115	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_35120	COG2409	Drug exporters of the RND superfamily
HUT10_35125	COG2197	response regulator
HUT10_35130	COG4585	Histidine kinase
HUT10_35140	COG0477	Major facilitator Superfamily
HUT10_35160	COG0028	Belongs to the TPP enzyme family
HUT10_35180	COG0667	Aldo Keto reductase
HUT10_35200	COG0473	3-isopropylmalate dehydrogenase activity
HUT10_35230	COG0154	amidase activity
HUT10_35275	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
HUT10_35290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT10_35300	COG0145	ligase activity
HUT10_35310	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_35330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_35335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT10_35425	COG2409	Drug exporters of the RND superfamily
HUT10_35455	COG0596	Alpha beta hydrolase
HUT10_35455	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_35485	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_35520	COG0596	Alpha beta hydrolase
HUT10_35525	COG2801	Transposase and inactivated derivatives
HUT10_35525	COG3415	Transposase
HUT10_35560	COG0018	arginyl-trna synthetase
HUT10_35565	COG0019	diaminopimelate decarboxylase activity
HUT10_35570	COG0460	homoserine dehydrogenase
HUT10_35575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT10_35580	COG0083	homoserine kinase activity
HUT10_35590	COG0254	rRNA binding
HUT10_35615	COG0463	Glycosyl transferase, family 2
HUT10_35620	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT10_35635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT10_35645	COG0356	it plays a direct role in the translocation of protons across the membrane
HUT10_35650	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT10_35655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT10_35660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT10_35670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT10_35675	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT10_35680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT10_35695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT10_35710	COG1309	transcriptional regulator
HUT10_35715	COG3631	Ketosteroid isomerase-related protein
HUT10_35720	COG0702	epimerase
HUT10_35730	COG1280	lysine exporter protein (LysE YggA)
HUT10_35735	COG1280	lysine exporter protein (LysE YggA)
HUT10_35740	COG1280	lysine exporter protein (LysE YggA)
HUT10_35755	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT10_35755	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT10_35760	COG1335	isochorismatase
HUT10_35765	COG4977	sequence-specific DNA binding
HUT10_35770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HUT10_35790	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HUT10_35820	COG2376	Dihydroxyacetone kinase
HUT10_35825	COG1461	Dihydroxyacetone kinase
HUT10_35855	COG1522	sequence-specific DNA binding
HUT10_35865	COG1522	sequence-specific DNA binding
HUT10_35870	COG0626	cystathionine gamma-synthase activity
HUT10_35900	COG2267	carboxylic ester hydrolase activity
HUT10_35910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT10_35915	COG0560	Phosphoserine phosphatase
HUT10_35915	COG3830	Belongs to the UPF0237 family
HUT10_35945	COG1268	BioY protein
HUT10_35955	COG0800	Aldolase
HUT10_35960	COG1335	isochorismatase
HUT10_35965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HUT10_35980	COG3191	aminopeptidase activity
HUT10_36010	COG1794	racemase activity, acting on amino acids and derivatives
HUT10_36025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUT10_36030	COG1234	tRNA 3'-trailer cleavage
HUT10_36035	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT10_36040	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUT10_36085	COG4977	sequence-specific DNA binding
HUT10_36120	COG1316	TRANSCRIPTIONal
HUT10_36135	COG3706	GGDEF domain
HUT10_36145	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_36165	COG2018	Roadblock/LC7 domain
HUT10_36180	COG2259	Doxx family
HUT10_36190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT10_36210	COG1408	metallophosphoesterase
HUT10_36265	COG2814	Major facilitator Superfamily
HUT10_36300	COG0662	Cupin 2, conserved barrel domain protein
HUT10_36320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_36325	COG0243	molybdopterin cofactor binding
HUT10_36335	COG0596	Alpha beta hydrolase
HUT10_36340	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_36360	COG1309	transcriptional regulator
HUT10_36365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUT10_36370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT10_36430	COG0667	Aldo Keto reductase
HUT10_36435	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_36450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_36490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_36515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT10_36535	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_36540	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_36575	COG0456	acetyltransferase
HUT10_36575	COG0454	-acetyltransferase
HUT10_36615	COG0745	RESPONSE REGULATOR receiver
HUT10_36620	COG4251	negative regulation of phosphorylation
HUT10_36625	COG0784	Response regulator, receiver
HUT10_36645	COG2837	iron assimilation
HUT10_36655	COG0640	Transcriptional regulator
HUT10_36675	COG0515	serine threonine protein kinase
HUT10_36675	COG2815	serine threonine protein kinase
HUT10_36700	COG5002	protein histidine kinase activity
HUT10_36705	COG0745	RESPONSE REGULATOR receiver
HUT10_36750	COG3226	Transcriptional regulator
HUT10_36755	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_36795	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_36825	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_36830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT10_36850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT10_36855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_36885	COG4981	capsule polysaccharide biosynthetic process
HUT10_36910	COG0500	methyltransferase
HUT10_36925	COG3655	Transcriptional regulator
HUT10_36940	COG2226	methyltransferase
HUT10_36950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_36970	COG2814	Major facilitator Superfamily
HUT10_36975	COG0789	Transcriptional regulator
HUT10_37045	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT10_37050	COG0129	dihydroxy-acid dehydratase activity
HUT10_37055	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_37065	COG1595	DNA-templated transcription, initiation
HUT10_37095	COG0604	alcohol dehydrogenase
HUT10_37110	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT10_37120	COG1609	Transcriptional regulator
HUT10_37125	COG1175	transmembrane transport
HUT10_37130	COG0395	ABC-type sugar transport system, permease component
HUT10_37140	COG3534	alpha-L-arabinofuranosidase
HUT10_37170	COG0477	Major facilitator Superfamily
HUT10_37185	COG0667	Aldo Keto reductase
HUT10_37190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT10_37205	COG0488	(ABC) transporter
HUT10_37235	COG2018	Roadblock/LC7 domain
HUT10_37280	COG1528	Iron-storage protein
HUT10_37290	COG1073	alpha beta
HUT10_37305	COG1131	(ABC) transporter
HUT10_37310	COG1725	Transcriptional regulator
HUT10_37325	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_37340	COG3629	intracellular signal transduction
HUT10_37340	COG3903	Transcriptional regulator
HUT10_37350	COG0587	DNA-directed DNA polymerase activity
HUT10_37355	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_37370	COG1309	transcriptional regulator
HUT10_37375	COG5297	Belongs to the glycosyl hydrolase family 6
HUT10_37375	COG4733	cellulase activity
HUT10_37385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_37390	COG0667	Aldo Keto reductase
HUT10_37405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT10_37415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_37445	COG3401	FG-GAP repeat protein
HUT10_37475	COG0463	Glycosyl transferase, family 2
HUT10_37485	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUT10_37500	COG0297	glycogen (starch) synthase activity
HUT10_37520	COG0438	transferase activity, transferring glycosyl groups
HUT10_37575	COG3345	alpha-galactosidase
HUT10_37585	COG1131	(ABC) transporter
HUT10_37610	COG4585	Histidine kinase
HUT10_37615	COG2197	response regulator
HUT10_37645	COG0346	lactoylglutathione lyase activity
HUT10_37655	COG1376	ErfK ybiS ycfS ynhG family protein
HUT10_37660	COG0477	Major facilitator Superfamily
HUT10_37670	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUT10_37675	COG0433	COG0433 Predicted ATPase
HUT10_37685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT10_37705	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT10_37720	COG3469	chitinase activity
HUT10_37725	COG2205	protein histidine kinase activity
HUT10_37730	COG0745	RESPONSE REGULATOR receiver
HUT10_37735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_37775	COG2801	Transposase and inactivated derivatives
HUT10_37775	COG3415	Transposase
HUT10_37780	COG1476	TRANSCRIPTIONal
HUT10_37790	COG1131	(ABC) transporter
HUT10_37820	COG0778	Nitroreductase
HUT10_37855	COG1797	cobyrinic acid a,c-diamide synthase activity
HUT10_37870	COG2378	regulation of single-species biofilm formation
HUT10_37875	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUT10_37880	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT10_37890	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT10_37895	COG1492	cobalamin metabolic process
HUT10_37935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_37945	COG0069	glutamate synthase activity
HUT10_37945	COG0067	glutamate synthase
HUT10_37945	COG0070	glutamate synthase
HUT10_37950	COG1739	Uncharacterized protein family UPF0029
HUT10_37955	COG3537	Alpha-1,2-mannosidase
HUT10_37960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_37970	COG1522	sequence-specific DNA binding
HUT10_37985	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT10_37990	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT10_38010	COG2197	response regulator
HUT10_38020	COG0247	lactate metabolic process
HUT10_38020	COG0277	FAD linked oxidase domain protein
HUT10_38025	COG1309	transcriptional regulator
HUT10_38035	COG2124	cytochrome p450
HUT10_38040	COG1695	Transcriptional regulator
HUT10_38055	COG0235	Class ii aldolase
HUT10_38055	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT10_38065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_38075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT10_38085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_38100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT10_38120	COG4941	Belongs to the sigma-70 factor family
HUT10_38135	COG1309	transcriptional regulator
HUT10_38170	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HUT10_38175	COG3706	GGDEF domain
HUT10_38200	COG1802	Transcriptional regulator
HUT10_38210	COG1796	DNA polymerase
HUT10_38210	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT10_38220	COG1309	transcriptional regulator
HUT10_38225	COG2072	flavoprotein involved in K transport
HUT10_38240	COG3268	Saccharopine dehydrogenase
HUT10_38255	COG1643	Atp-dependent helicase
HUT10_38275	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_38310	COG1024	Enoyl-CoA hydratase
HUT10_38355	COG0583	DNA-binding transcription factor activity
HUT10_38360	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT10_38380	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT10_38405	COG3835	regulator
HUT10_38435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT10_38440	COG0531	amino acid
HUT10_38475	COG1609	Transcriptional regulator
HUT10_38495	COG2130	NADP-dependent
HUT10_38505	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_38540	COG0277	FAD linked oxidase domain protein
HUT10_38545	COG2226	methyltransferase
HUT10_38580	COG0366	Alpha amylase catalytic
HUT10_38590	COG1175	transmembrane transport
HUT10_38600	COG1609	Transcriptional regulator
HUT10_38645	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT10_38655	COG4221	oxidoreductase activity
HUT10_38660	COG2267	carboxylic ester hydrolase activity
HUT10_38680	COG1376	ErfK ybiS ycfS ynhG family protein
HUT10_38690	COG0586	Pfam SNARE associated Golgi protein
HUT10_38695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT10_38710	COG1309	transcriptional regulator
HUT10_38720	COG0321	lipoyl(octanoyl) transferase activity
HUT10_38735	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_38740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT10_38750	COG2801	Transposase and inactivated derivatives
HUT10_38750	COG3415	Transposase
HUT10_38785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT10_38810	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT10_38820	COG0667	Aldo Keto reductase
HUT10_38845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_38855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT10_38890	COG1845	cytochrome c oxidase, subunit III
HUT10_38895	COG2010	Cytochrome c
HUT10_38905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT10_38955	COG2124	cytochrome p450
HUT10_38960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT10_38965	COG0659	secondary active sulfate transmembrane transporter activity
HUT10_38970	COG0659	secondary active sulfate transmembrane transporter activity
HUT10_38975	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT10_38995	COG0501	Belongs to the peptidase M48B family
HUT10_39000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT10_39010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUT10_39015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT10_39020	COG0157	Belongs to the NadC ModD family
HUT10_39025	COG1404	Belongs to the peptidase S8 family
HUT10_39030	COG2801	Transposase and inactivated derivatives
HUT10_39075	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_39110	COG1674	ftsk spoiiie
HUT10_39135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT10_39145	COG5520	Belongs to the glycosyl hydrolase 30 family
HUT10_39165	COG4566	intracellular signal transduction
HUT10_39170	COG2197	response regulator
HUT10_39180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT10_39190	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT10_39200	COG2409	Drug exporters of the RND superfamily
HUT10_39205	COG1309	transcriptional regulator
HUT10_39210	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUT10_39220	COG3959	Transketolase, thiamine diphosphate binding domain
HUT10_39240	COG1960	acyl-CoA dehydrogenase activity
HUT10_39255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUT10_39260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT10_39265	COG3226	Transcriptional regulator
HUT10_39295	COG0107	imidazoleglycerol-phosphate synthase activity
HUT10_39340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT10_39350	COG0134	indole-3-glycerol-phosphate synthase activity
HUT10_39355	COG0133	tryptophan synthase activity
HUT10_39360	COG0159	tryptophan synthase activity
HUT10_39370	COG0174	glutamine synthetase
HUT10_39385	COG1473	amidohydrolase
HUT10_39390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT10_39400	COG0067	glutamate synthase
HUT10_39400	COG0069	glutamate synthase activity
HUT10_39400	COG0070	glutamate synthase
HUT10_39435	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT10_39460	COG2268	Band 7 protein
HUT10_39470	COG2815	serine threonine protein kinase
HUT10_39470	COG0515	serine threonine protein kinase
HUT10_39560	COG0242	peptide deformylase activity
HUT10_39570	COG1349	DNA-binding transcription factor activity
HUT10_39580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUT10_39585	COG0443	Heat shock 70 kDa protein
HUT10_39595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT10_39600	COG2137	regulation of response to DNA damage stimulus
HUT10_39615	COG0800	Aldolase
HUT10_39635	COG1053	succinate dehydrogenase
HUT10_39650	COG1228	amidohydrolase
HUT10_39685	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_39690	COG0765	amino acid transport
HUT10_39695	COG0765	amino acid transport
HUT10_39700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_39705	COG1126	abc transporter atp-binding protein
HUT10_39715	COG0642	Histidine kinase
HUT10_39730	COG3321	synthase
HUT10_39730	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_39730	COG0604	alcohol dehydrogenase
HUT10_39800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT10_39815	COG1196	nuclear chromosome segregation
HUT10_39820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT10_39830	COG0525	valine-tRNA ligase activity
HUT10_39845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT10_39855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT10_39865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT10_39895	COG1505	serine-type exopeptidase activity
HUT10_39935	COG2936	dipeptidyl-peptidase activity
HUT10_39940	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUT10_39950	COG2197	response regulator
HUT10_39970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT10_39975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUT10_39990	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUT10_40005	COG1960	acyl-CoA dehydrogenase activity
HUT10_40010	COG1960	acyl-CoA dehydrogenase activity
HUT10_40020	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_40030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_40035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_40090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_40105	COG1609	Transcriptional regulator
HUT10_40120	COG0395	ABC-type sugar transport system, permease component
HUT10_40135	COG1022	Amp-dependent synthetase and ligase
HUT10_40155	COG0003	Pfam Anion-transporting ATPase
HUT10_40165	COG1940	carbohydrate kinase activity
HUT10_40175	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_40200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUT10_40225	COG1733	regulation of RNA biosynthetic process
HUT10_40230	COG0640	Transcriptional regulator
HUT10_40255	COG1946	Acyl-CoA thioesterase
HUT10_40275	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_40275	COG1672	PFAM Archaeal ATPase
HUT10_40280	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_40295	COG1960	acyl-CoA dehydrogenase activity
HUT10_40300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_40345	COG1309	transcriptional regulator
HUT10_40350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_40365	COG2018	Roadblock/LC7 domain
HUT10_40380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT10_40400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT10_40400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT10_40400	COG1703	isobutyryl-CoA mutase activity
HUT10_40405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_40415	COG1309	transcriptional regulator
HUT10_40420	COG1960	acyl-CoA dehydrogenase activity
HUT10_40425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT10_40445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_40450	COG0748	coenzyme F420 binding
HUT10_40460	COG1960	acyl-CoA dehydrogenase activity
HUT10_40465	COG1960	acyl-CoA dehydrogenase activity
HUT10_40470	COG2030	dehydratase
HUT10_40490	COG0196	riboflavin kinase activity
HUT10_40495	COG2030	dehydratase
HUT10_40525	COG1960	acyl-CoA dehydrogenase activity
HUT10_40530	COG2267	carboxylic ester hydrolase activity
HUT10_40535	COG0346	lactoylglutathione lyase activity
HUT10_40540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT10_40565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT10_40595	COG0477	Major facilitator Superfamily
HUT10_40600	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT10_40650	COG1473	amidohydrolase
HUT10_40660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_40665	COG1228	amidohydrolase
HUT10_40670	COG0596	Alpha beta hydrolase
HUT10_40675	COG0251	oxidation-reduction process
HUT10_40680	COG0183	Belongs to the thiolase family
HUT10_40685	COG2124	cytochrome p450
HUT10_40700	COG1295	ribonuclease BN
HUT10_40740	COG2070	2-Nitropropane dioxygenase
HUT10_40755	COG2188	Transcriptional regulator
HUT10_40775	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT10_40775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT10_40785	COG1490	D-aminoacyl-tRNA deacylase activity
HUT10_40795	COG1473	amidohydrolase
HUT10_40810	COG2313	pseudouridylate synthase activity
HUT10_40835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT10_40845	COG1061	Type III restriction enzyme res subunit
HUT10_40850	COG4213	ABC transporter substrate-binding protein
HUT10_40860	COG4214	carbohydrate transport
HUT10_40890	COG0531	amino acid
HUT10_40935	COG0366	Alpha amylase catalytic
HUT10_40940	COG0366	Alpha amylase catalytic
HUT10_40950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT10_40965	COG1940	carbohydrate kinase activity
HUT10_40970	COG0483	inositol monophosphate 1-phosphatase activity
HUT10_40990	COG0756	dUTP diphosphatase activity
HUT10_41020	COG0569	domain protein
HUT10_41025	COG0531	amino acid
HUT10_41030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT10_41045	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_41050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT10_41060	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_41065	COG0028	Belongs to the TPP enzyme family
HUT10_41085	COG0745	RESPONSE REGULATOR receiver
HUT10_41090	COG2205	protein histidine kinase activity
HUT10_41110	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_41110	COG1024	Enoyl-CoA hydratase
HUT10_41115	COG0183	Belongs to the thiolase family
HUT10_41160	COG1309	transcriptional regulator
HUT10_41175	COG2197	response regulator
HUT10_41185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT10_41200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_41220	COG3220	belongs to the UPF0276 family
HUT10_41235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT10_41270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_41275	COG0539	negative regulation of cytoplasmic translation
HUT10_41285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HUT10_41285	COG2508	Transcriptional regulator
HUT10_41290	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_41295	COG0506	proline dehydrogenase activity
HUT10_41300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT10_41315	COG4941	Belongs to the sigma-70 factor family
HUT10_41325	COG1793	dna ligase
HUT10_41355	COG1302	Protein conserved in bacteria
HUT10_41365	COG1595	DNA-templated transcription, initiation
HUT10_41400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT10_41405	COG0640	Transcriptional regulator
HUT10_41415	COG2326	polyphosphate kinase activity
HUT10_41435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT10_41440	COG1993	acr, cog1993
HUT10_41445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT10_41465	COG0174	glutamine synthetase
HUT10_41475	COG1672	PFAM Archaeal ATPase
HUT10_41475	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_41495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT10_41520	COG2124	cytochrome p450
HUT10_41540	COG2084	Dehydrogenase
HUT10_41555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT10_41565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUT10_41570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT10_41575	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUT10_41580	COG1309	transcriptional regulator
HUT10_41590	COG1073	alpha beta
HUT10_41615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT10_41620	COG1263	PTS System
HUT10_41625	COG2188	Transcriptional regulator
HUT10_41630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT10_41635	COG2190	(PTS) system
HUT10_41635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT10_41635	COG1263	PTS System
HUT10_41660	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT10_41665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT10_41670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT10_41675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT10_41680	COG0346	lactoylglutathione lyase activity
HUT10_41700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT10_41705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT10_41720	COG0540	Belongs to the ATCase OTCase family
HUT10_41735	COG0505	Belongs to the CarA family
HUT10_41745	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT10_41755	COG0194	GDP metabolic process
HUT10_41760	COG1758	RNA polymerase activity
HUT10_41770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT10_41805	COG0405	Gamma-glutamyltransferase
HUT10_41810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT10_41835	COG2197	response regulator
HUT10_41840	COG4585	Histidine kinase
HUT10_41855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_41855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_41860	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT10_41880	COG0322	excinuclease ABC activity
HUT10_41885	COG1660	Displays ATPase and GTPase activities
HUT10_41895	COG1481	regulation of sporulation
HUT10_41900	COG0463	Glycosyl transferase, family 2
HUT10_41925	COG3250	beta-galactosidase activity
HUT10_41930	COG0408	coproporphyrinogen oxidase activity
HUT10_41965	COG1280	lysine exporter protein (LysE YggA)
HUT10_41975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT10_41980	COG0126	phosphoglycerate kinase activity
HUT10_41985	COG0149	triose-phosphate isomerase activity
HUT10_42015	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_42020	COG0363	glucosamine-6-phosphate deaminase activity
HUT10_42035	COG0166	Belongs to the GPI family
HUT10_42040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT10_42050	COG0109	protoheme IX farnesyltransferase activity
HUT10_42115	COG3415	Transposase
HUT10_42115	COG2801	Transposase and inactivated derivatives
HUT10_42155	COG0396	ATPase activity
HUT10_42170	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT10_42180	COG1742	UPF0060 membrane protein
HUT10_42190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT10_42240	COG2199	diguanylate cyclase activity
HUT10_42240	COG2200	EAL domain
HUT10_42260	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT10_42275	COG0488	(ABC) transporter
HUT10_42300	COG1132	(ABC) transporter
HUT10_42310	COG4821	SIS domain
HUT10_42320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_42325	COG1316	TRANSCRIPTIONal
HUT10_42330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_42340	COG5001	Diguanylate cyclase
HUT10_42340	COG3300	MHYT domain
HUT10_42360	COG0494	nUDIX hydrolase
HUT10_42370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT10_42370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT10_42380	COG1024	Enoyl-CoA hydratase
HUT10_42395	COG1960	acyl-CoA dehydrogenase activity
HUT10_42400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_42415	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_42445	COG3469	chitinase activity
HUT10_42450	COG3706	GGDEF domain
HUT10_42480	COG1309	transcriptional regulator
HUT10_42485	COG1376	ErfK ybiS ycfS ynhG family protein
HUT10_42520	COG4585	Histidine kinase
HUT10_42525	COG2197	response regulator
HUT10_42545	COG1120	ATPase activity
HUT10_42635	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT10_42650	COG1846	Transcriptional regulator
HUT10_42665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_42680	COG1595	DNA-templated transcription, initiation
HUT10_42690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUT10_42705	COG1799	cell septum assembly
HUT10_42725	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT10_42730	COG0768	penicillin binding
HUT10_42735	COG0640	Transcriptional regulator
HUT10_42745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT10_42755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT10_42780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_42790	COG0248	Ppx GppA phosphatase
HUT10_42835	COG2801	Transposase and inactivated derivatives
HUT10_42835	COG3415	Transposase
HUT10_42850	COG1940	carbohydrate kinase activity
HUT10_42850	COG1846	Transcriptional regulator
HUT10_42895	COG1309	transcriptional regulator
HUT10_42900	COG4221	oxidoreductase activity
HUT10_42905	COG0667	Aldo Keto reductase
HUT10_42910	COG0542	response to heat
HUT10_42920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT10_42930	COG0514	ATP-dependent DNA helicase (RecQ)
HUT10_42940	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_42975	COG2205	protein histidine kinase activity
HUT10_42980	COG0745	RESPONSE REGULATOR receiver
HUT10_43060	COG0604	alcohol dehydrogenase
HUT10_43070	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HUT10_43095	COG4585	Histidine kinase
HUT10_43105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_43110	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_43115	COG2080	2 iron, 2 sulfur cluster binding
HUT10_43140	COG2188	Transcriptional regulator
HUT10_43155	COG2172	sigma factor antagonist activity
HUT10_43160	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT10_43165	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT10_43180	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_43185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT10_43200	COG3546	catalase activity
HUT10_43210	COG0702	epimerase
HUT10_43215	COG1733	regulation of RNA biosynthetic process
HUT10_43230	COG1609	Transcriptional regulator
HUT10_43240	COG1175	transmembrane transport
HUT10_43245	COG0395	ABC-type sugar transport system, permease component
HUT10_43265	COG0667	Aldo Keto reductase
HUT10_43290	COG0667	Aldo Keto reductase
HUT10_43310	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HUT10_43315	COG1691	(AIR) carboxylase
HUT10_43320	COG3875	lactate racemase activity
HUT10_43325	COG3618	amidohydrolase
HUT10_43330	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_43335	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_43340	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_43350	COG1129	ABC transporter
HUT10_43400	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_43420	COG3251	PFAM MbtH domain protein
HUT10_43440	COG2124	cytochrome p450
HUT10_43500	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_43515	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_43535	COG0583	DNA-binding transcription factor activity
HUT10_43545	COG4221	oxidoreductase activity
HUT10_43550	COG0583	DNA-binding transcription factor activity
HUT10_43560	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_43565	COG0395	ABC-type sugar transport system, permease component
HUT10_43570	COG3833	ABC-type maltose transport systems, permease component
HUT10_43610	COG2175	clavaminate synthase activity
HUT10_43615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_43615	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_43615	COG3321	synthase
HUT10_43615	COG4221	oxidoreductase activity
HUT10_43665	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT10_43700	COG2018	Roadblock/LC7 domain
HUT10_43705	COG5002	protein histidine kinase activity
HUT10_43735	COG1940	carbohydrate kinase activity
HUT10_43745	COG1129	ABC transporter
HUT10_43750	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_43760	COG0673	inositol 2-dehydrogenase activity
HUT10_43825	COG4946	Tricorn protease homolog
HUT10_43825	COG0793	Belongs to the peptidase S41A family
HUT10_43855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_43900	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT10_43915	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_43920	COG1131	(ABC) transporter
HUT10_43975	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_43995	COG0019	diaminopimelate decarboxylase activity
HUT10_44000	COG3903	Transcriptional regulator
HUT10_44000	COG3629	intracellular signal transduction
HUT10_44010	COG0747	negative chemotaxis
HUT10_44020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT10_44040	COG0604	alcohol dehydrogenase
HUT10_44080	COG0702	epimerase
HUT10_44085	COG1733	regulation of RNA biosynthetic process
HUT10_44095	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_44145	COG0765	amino acid transport
HUT10_44160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_44190	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_44205	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT10_44210	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_44230	COG2508	Transcriptional regulator
HUT10_44235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_44245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_44250	COG1215	transferase activity, transferring glycosyl groups
HUT10_44260	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_44270	COG3158	transport of potassium into the cell
HUT10_44275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT10_44275	COG0438	transferase activity, transferring glycosyl groups
HUT10_44285	COG2205	protein histidine kinase activity
HUT10_44295	COG3903	Transcriptional regulator
HUT10_44295	COG3629	intracellular signal transduction
HUT10_44315	COG1335	isochorismatase
HUT10_44345	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_44365	COG3629	intracellular signal transduction
HUT10_44365	COG3903	Transcriptional regulator
HUT10_44370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_44385	COG2197	response regulator
HUT10_44395	COG1136	(ABC) transporter
HUT10_44395	COG0577	efflux transmembrane transporter activity
HUT10_44405	COG0445	tRNA wobble uridine modification
HUT10_44455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT10_44480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT10_44485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_44490	COG3903	Transcriptional regulator
HUT10_44490	COG3629	intracellular signal transduction
HUT10_44495	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT10_44510	COG3509	depolymerase
HUT10_44520	COG0583	DNA-binding transcription factor activity
HUT10_44685	COG2124	cytochrome p450
HUT10_44690	COG2867	negative regulation of translational initiation
HUT10_44690	COG2226	methyltransferase
HUT10_44695	COG0662	Cupin 2, conserved barrel domain protein
HUT10_44745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT10_44750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT10_44755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_44765	COG0395	ABC-type sugar transport system, permease component
HUT10_44780	COG1609	Transcriptional regulator
HUT10_44865	COG3831	ATPase activity
HUT10_44885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_44895	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUT10_44905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUT10_44910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT10_44915	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HUT10_44920	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_44925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUT10_44955	COG3661	Belongs to the glycosyl hydrolase 67 family
HUT10_45010	COG2201	protein-glutamate methylesterase activity
HUT10_45025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT10_45100	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_45105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HUT10_45125	COG0702	epimerase
HUT10_45155	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT10_45170	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_45195	COG0444	Belongs to the ABC transporter superfamily
HUT10_45200	COG4608	Belongs to the ABC transporter superfamily
HUT10_45210	COG0477	Major facilitator Superfamily
HUT10_45240	COG0477	Major facilitator Superfamily
HUT10_45250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT10_45260	COG3903	Transcriptional regulator
HUT10_45260	COG3629	intracellular signal transduction
HUT10_45265	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT10_45280	COG0235	Class ii aldolase
HUT10_45285	COG0701	Predicted permease
HUT10_45320	COG0366	Alpha amylase catalytic
HUT10_45320	COG1470	cell adhesion involved in biofilm formation
HUT10_45330	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_45345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_45345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_45365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_45390	COG2080	2 iron, 2 sulfur cluster binding
HUT10_45395	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_45400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_45460	COG3903	Transcriptional regulator
HUT10_45460	COG3629	intracellular signal transduction
HUT10_45500	COG2076	Multidrug Resistance protein
HUT10_45520	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT10_45530	COG0745	RESPONSE REGULATOR receiver
HUT10_45535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_45545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT10_45550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT10_45565	COG4172	Belongs to the ABC transporter superfamily
HUT10_45575	COG1309	transcriptional regulator
HUT10_45580	COG2957	Belongs to the agmatine deiminase family
HUT10_45585	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_45595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT10_45605	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_45605	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_45610	COG2197	response regulator
HUT10_45620	COG1131	(ABC) transporter
HUT10_45635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT10_45640	COG4279	zinc finger
HUT10_45685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_45705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT10_45740	COG3118	belongs to the thioredoxin family
HUT10_45745	COG0542	response to heat
HUT10_45755	COG0484	heat shock protein binding
HUT10_45760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT10_45765	COG0443	Heat shock 70 kDa protein
HUT10_45785	COG0366	Alpha amylase catalytic
HUT10_45845	COG1595	DNA-templated transcription, initiation
HUT10_45875	COG3693	PFAM glycoside hydrolase, family 10
HUT10_45905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT10_45915	COG1063	alcohol dehydrogenase
HUT10_45920	COG0300	oxidoreductase activity
HUT10_45925	COG1309	transcriptional regulator
HUT10_45935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_45945	COG0542	response to heat
HUT10_45950	COG1271	oxidase subunit
HUT10_45955	COG1294	oxidase, subunit
HUT10_45985	COG1595	DNA-templated transcription, initiation
HUT10_45995	COG1404	Belongs to the peptidase S8 family
HUT10_46005	COG3246	L-lysine catabolic process to acetate
HUT10_46030	COG0477	Major facilitator Superfamily
HUT10_46055	COG0583	DNA-binding transcription factor activity
HUT10_46120	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_46130	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_46130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_46130	COG0300	oxidoreductase activity
HUT10_46130	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_46130	COG3321	synthase
HUT10_46135	COG3321	synthase
HUT10_46135	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_46135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_46135	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_46135	COG0300	oxidoreductase activity
HUT10_46140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_46140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_46140	COG3321	synthase
HUT10_46140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_46140	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_46175	COG4221	oxidoreductase activity
HUT10_46175	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_46175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_46175	COG3321	synthase
HUT10_46200	COG0488	(ABC) transporter
HUT10_46210	COG0659	secondary active sulfate transmembrane transporter activity
HUT10_46225	COG0596	Alpha beta hydrolase
HUT10_46250	COG3903	Transcriptional regulator
HUT10_46250	COG3629	intracellular signal transduction
HUT10_46290	COG2319	Wd-40 repeat
HUT10_46290	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT10_46305	COG0714	Associated with various cellular activities
HUT10_46315	COG3629	intracellular signal transduction
HUT10_46365	COG0702	epimerase
HUT10_46410	COG2205	protein histidine kinase activity
HUT10_46415	COG0745	RESPONSE REGULATOR receiver
HUT10_46465	COG0789	Transcriptional regulator
HUT10_46465	COG4978	Transcriptional regulator
HUT10_46545	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_46695	COG0302	gtp cyclohydrolase
HUT10_46700	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_46705	COG1819	glycosyl
HUT10_46720	COG0702	epimerase
HUT10_46840	COG0309	Hydrogenase expression formation protein (HypE)
HUT10_46845	COG0409	Hydrogenase expression formation protein
HUT10_46850	COG0298	carbon dioxide binding
HUT10_46935	COG2205	protein histidine kinase activity
HUT10_46955	COG1846	Transcriptional regulator
HUT10_46965	COG1830	Aldolase
HUT10_46975	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT10_46980	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT10_46985	COG0493	'glutamate synthase
HUT10_47000	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_47020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT10_47060	COG2326	polyphosphate kinase activity
HUT10_47075	COG0589	response to stress
HUT10_47080	COG2239	Acts as a magnesium transporter
HUT10_47120	COG0516	GMP reductase activity
HUT10_47120	COG0517	IMP dehydrogenase activity
HUT10_47130	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HUT10_47150	COG4988	ABC transporter
HUT10_47155	COG1294	oxidase, subunit
HUT10_47190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUT10_47230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT10_47230	COG0574	Belongs to the PEP-utilizing enzyme family
HUT10_47235	COG1131	(ABC) transporter
HUT10_47240	COG3559	Exporter of polyketide antibiotics
HUT10_47255	COG2239	Acts as a magnesium transporter
HUT10_47265	COG0589	response to stress
HUT10_47280	COG1063	alcohol dehydrogenase
HUT10_47330	COG0330	HflC and HflK could
HUT10_47335	COG1252	NADH dehydrogenase
HUT10_47450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_47480	COG3250	beta-galactosidase activity
HUT10_47495	COG0583	DNA-binding transcription factor activity
HUT10_47505	COG0477	Major facilitator Superfamily
HUT10_47535	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HUT10_47560	COG0778	Nitroreductase
HUT10_47585	COG0477	Major facilitator Superfamily
HUT10_47600	COG0300	oxidoreductase activity
HUT10_47620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_47635	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_47645	COG1960	acyl-CoA dehydrogenase activity
HUT10_47680	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_47725	COG0656	L-ascorbic acid biosynthetic process
HUT10_47735	COG1063	alcohol dehydrogenase
HUT10_47760	COG3629	intracellular signal transduction
HUT10_47760	COG3903	Transcriptional regulator
HUT10_47770	COG2205	protein histidine kinase activity
HUT10_47795	COG0438	transferase activity, transferring glycosyl groups
HUT10_47805	COG0667	Aldo Keto reductase
HUT10_47845	COG3629	intracellular signal transduction
HUT10_47845	COG3903	Transcriptional regulator
HUT10_47850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUT10_47885	COG2226	methyltransferase
HUT10_47895	COG0640	Transcriptional regulator
HUT10_47900	COG0798	PFAM Bile acid sodium symporter
HUT10_47910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT10_47920	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT10_47925	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HUT10_47930	COG0235	Class ii aldolase
HUT10_47930	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HUT10_47935	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HUT10_47945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT10_47970	COG2226	methyltransferase
HUT10_47985	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT10_47995	COG0243	molybdopterin cofactor binding
HUT10_48075	COG0789	Transcriptional regulator
HUT10_48125	COG0494	nUDIX hydrolase
HUT10_48275	COG0714	Associated with various cellular activities
HUT10_48300	COG0791	NLP P60 protein
HUT10_48300	COG3883	PFAM NLP P60 protein
HUT10_48355	COG1063	alcohol dehydrogenase
HUT10_48415	COG1672	PFAM Archaeal ATPase
HUT10_48415	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_48440	COG1802	Transcriptional regulator
HUT10_48445	COG1063	alcohol dehydrogenase
HUT10_48475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_48490	COG1733	regulation of RNA biosynthetic process
HUT10_48495	COG1335	isochorismatase
HUT10_48505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_48520	COG1942	4-Oxalocrotonate Tautomerase
HUT10_48530	COG3971	2-oxopent-4-enoate hydratase activity
HUT10_48550	COG1355	regulation of microtubule-based process
HUT10_48575	COG0300	oxidoreductase activity
HUT10_48580	COG2814	Major facilitator Superfamily
HUT10_48595	COG0006	proline dipeptidase activity
HUT10_48605	COG1609	Transcriptional regulator
HUT10_48625	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_48630	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_48635	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_48675	COG1196	nuclear chromosome segregation
HUT10_48725	COG0778	Nitroreductase
HUT10_48730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT10_48755	COG0438	transferase activity, transferring glycosyl groups
HUT10_48780	COG3608	succinylglutamate desuccinylase aspartoacylase
HUT10_48780	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUT10_48790	COG0277	FAD linked oxidase domain protein
HUT10_48800	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUT10_48815	COG1396	sequence-specific DNA binding
HUT10_48830	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUT10_48835	COG0217	transcriptional regulatory protein
HUT10_48855	COG0632	four-way junction helicase activity
HUT10_48860	COG2255	four-way junction helicase activity
HUT10_48865	COG1862	Preprotein translocase
HUT10_48875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT10_48880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT10_48885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT10_48890	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_48925	COG1073	alpha beta
HUT10_48945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUT10_48950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_48980	COG3629	intracellular signal transduction
HUT10_48980	COG3903	Transcriptional regulator
HUT10_49015	COG2205	protein histidine kinase activity
HUT10_49020	COG2018	Roadblock/LC7 domain
HUT10_49040	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT10_49055	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT10_49100	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_49130	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_49205	COG3209	COG3209 Rhs family protein
HUT10_49215	COG0477	Major facilitator Superfamily
HUT10_49235	COG3973	AAA domain
HUT10_49235	COG3973	AAA domain
HUT10_49250	COG0019	diaminopimelate decarboxylase activity
HUT10_49255	COG0583	DNA-binding transcription factor activity
HUT10_49295	COG0656	L-ascorbic acid biosynthetic process
HUT10_49325	COG2172	sigma factor antagonist activity
HUT10_49360	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT10_49365	COG1573	uracil-dna glycosylase
HUT10_49380	COG0129	dihydroxy-acid dehydratase activity
HUT10_49390	COG0395	ABC-type sugar transport system, permease component
HUT10_49410	COG4733	cellulase activity
HUT10_49410	COG5297	Belongs to the glycosyl hydrolase family 6
HUT10_49415	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT10_49420	COG5297	Belongs to the glycosyl hydrolase family 6
HUT10_49425	COG0456	acetyltransferase
HUT10_49450	COG0667	Aldo Keto reductase
HUT10_49455	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT10_49490	COG2814	Major facilitator Superfamily
HUT10_49520	COG1324	tolerance protein
HUT10_49535	COG2197	response regulator
HUT10_49545	COG4585	Histidine kinase
HUT10_49550	COG2201	protein-glutamate methylesterase activity
HUT10_49595	COG0019	diaminopimelate decarboxylase activity
HUT10_49600	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HUT10_49620	COG2409	Drug exporters of the RND superfamily
HUT10_49630	COG0667	Aldo Keto reductase
HUT10_49650	COG2770	Histidine kinase
HUT10_49650	COG2208	phosphoserine phosphatase activity
HUT10_49695	COG1309	transcriptional regulator
HUT10_49700	COG0596	Alpha beta hydrolase
HUT10_49710	COG1309	transcriptional regulator
HUT10_49735	COG3321	synthase
HUT10_49735	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_49735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_49735	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_49735	COG0300	oxidoreductase activity