locus-tag	class	description
CVV72_00010	COG2010	Cytochrome c
CVV72_00020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CVV72_00050	COG0438	transferase activity, transferring glycosyl groups
CVV72_00065	COG2124	cytochrome p450
CVV72_00070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CVV72_00080	COG0659	secondary active sulfate transmembrane transporter activity
CVV72_00085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CVV72_00110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CVV72_00120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CVV72_00125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CVV72_00135	COG1404	Belongs to the peptidase S8 family
CVV72_00180	COG3896	Chloramphenicol phosphotransferase-like protein
CVV72_00195	COG1674	ftsk spoiiie
CVV72_00245	COG2197	response regulator
CVV72_00250	COG3386	PFAM SMP-30 Gluconolaconase
CVV72_00265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CVV72_00275	COG0131	Imidazoleglycerol-phosphate dehydratase
CVV72_00280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CVV72_00295	COG2409	Drug exporters of the RND superfamily
CVV72_00300	COG1309	transcriptional regulator
CVV72_00310	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CVV72_00320	COG3959	Transketolase, thiamine diphosphate binding domain
CVV72_00325	COG3958	Transketolase
CVV72_00350	COG1960	acyl-CoA dehydrogenase activity
CVV72_00360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CVV72_00365	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CVV72_00405	COG1309	transcriptional regulator
CVV72_00410	COG0107	imidazoleglycerol-phosphate synthase activity
CVV72_00420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CVV72_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CVV72_00460	COG0134	indole-3-glycerol-phosphate synthase activity
CVV72_00465	COG0133	tryptophan synthase activity
CVV72_00470	COG0159	tryptophan synthase activity
CVV72_00475	COG0174	glutamine synthetase
CVV72_00485	COG1473	amidohydrolase
CVV72_00490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CVV72_00505	COG0067	glutamate synthase
CVV72_00505	COG0069	glutamate synthase activity
CVV72_00505	COG0070	glutamate synthase
CVV72_00530	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CVV72_00540	COG2318	DinB family
CVV72_00550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CVV72_00565	COG1595	DNA-templated transcription, initiation
CVV72_00585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CVV72_00590	COG1799	cell septum assembly
CVV72_00600	COG3599	regulation of cell shape
CVV72_00625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CVV72_00635	COG0640	Transcriptional regulator
CVV72_00650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CVV72_00660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CVV72_00680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_00685	COG0248	Ppx GppA phosphatase
CVV72_00705	COG1309	transcriptional regulator
CVV72_00720	COG1846	Transcriptional regulator
CVV72_00720	COG1940	carbohydrate kinase activity
CVV72_00735	COG2010	Cytochrome c
CVV72_00735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CVV72_00750	COG0667	Aldo Keto reductase
CVV72_00755	COG2226	methyltransferase
CVV72_00760	COG0667	Aldo Keto reductase
CVV72_00780	COG0477	Major facilitator Superfamily
CVV72_00785	COG0542	response to heat
CVV72_00805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CVV72_00815	COG0514	ATP-dependent DNA helicase (RecQ)
CVV72_00825	COG0640	Transcriptional regulator
CVV72_00860	COG0142	geranyltranstransferase activity
CVV72_00880	COG1051	belongs to the nudix hydrolase family
CVV72_00885	COG0596	Alpha beta hydrolase
CVV72_00930	COG3903	Transcriptional regulator
CVV72_00930	COG3629	intracellular signal transduction
CVV72_00940	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CVV72_00950	COG1280	lysine exporter protein (LysE YggA)
CVV72_00960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CVV72_00970	COG3237	CsbD-like
CVV72_00985	COG1595	DNA-templated transcription, initiation
CVV72_01020	COG1302	Protein conserved in bacteria
CVV72_01025	COG1785	Belongs to the alkaline phosphatase family
CVV72_01060	COG0574	Belongs to the PEP-utilizing enzyme family
CVV72_01060	COG3848	Pyruvate phosphate dikinase
CVV72_01085	COG5002	protein histidine kinase activity
CVV72_01090	COG0745	RESPONSE REGULATOR receiver
CVV72_01125	COG0587	DNA-directed DNA polymerase activity
CVV72_01220	COG2197	response regulator
CVV72_01235	COG3033	Beta-eliminating lyase
CVV72_01240	COG0475	glutathione-regulated potassium exporter activity
CVV72_01265	COG0596	Alpha beta hydrolase
CVV72_01275	COG1472	Belongs to the glycosyl hydrolase 3 family
CVV72_01280	COG0561	phosphatase activity
CVV72_01285	COG1216	Glycosyl transferase, family 2
CVV72_01290	COG0297	glycogen (starch) synthase activity
CVV72_01300	COG0717	Belongs to the dCTP deaminase family
CVV72_01310	COG0726	polysaccharide deacetylase
CVV72_01315	COG0738	Major facilitator superfamily
CVV72_01330	COG3629	intracellular signal transduction
CVV72_01330	COG3903	Transcriptional regulator
CVV72_01340	COG2423	ornithine cyclodeaminase activity
CVV72_01345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CVV72_01350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CVV72_01370	COG3629	intracellular signal transduction
CVV72_01370	COG3903	Transcriptional regulator
CVV72_01385	COG1366	Belongs to the anti-sigma-factor antagonist family
CVV72_01395	COG1793	dna ligase
CVV72_01395	COG3285	dna ligase
CVV72_01405	COG1131	(ABC) transporter
CVV72_01445	COG4172	Belongs to the ABC transporter superfamily
CVV72_01450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVV72_01455	COG0601	transmembrane transport
CVV72_01485	COG2271	Major facilitator Superfamily
CVV72_01490	COG4977	sequence-specific DNA binding
CVV72_01510	COG2172	sigma factor antagonist activity
CVV72_01515	COG1366	Belongs to the anti-sigma-factor antagonist family
CVV72_01520	COG1366	Belongs to the anti-sigma-factor antagonist family
CVV72_01545	COG4829	muconolactone delta-isomerase
CVV72_01550	COG3485	protocatechuate 3,4-dioxygenase
CVV72_01560	COG0583	DNA-binding transcription factor activity
CVV72_01565	COG3629	intracellular signal transduction
CVV72_01565	COG3903	Transcriptional regulator
CVV72_01580	COG0747	negative chemotaxis
CVV72_01590	COG0444	Belongs to the ABC transporter superfamily
CVV72_01595	COG4608	Belongs to the ABC transporter superfamily
CVV72_01625	COG2197	response regulator
CVV72_01630	COG4585	Histidine kinase
CVV72_01645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CVV72_01660	COG0288	reversible hydration of carbon dioxide
CVV72_01695	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_01700	COG1309	transcriptional regulator
CVV72_01705	COG1414	Transcriptional regulator
CVV72_01710	COG3734	2-keto-3-deoxy-galactonokinase
CVV72_01715	COG0800	Aldolase
CVV72_01720	COG4948	Mandelate Racemase Muconate Lactonizing
CVV72_01725	COG2271	Major facilitator Superfamily
CVV72_01735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CVV72_01745	COG1595	DNA-templated transcription, initiation
CVV72_01750	COG0666	response to abiotic stimulus
CVV72_01760	COG4585	Histidine kinase
CVV72_01765	COG2197	response regulator
CVV72_01790	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_01845	COG0604	alcohol dehydrogenase
CVV72_01895	COG2197	response regulator
CVV72_01910	COG2197	response regulator
CVV72_01915	COG2197	response regulator
CVV72_01940	COG1733	regulation of RNA biosynthetic process
CVV72_01950	COG0596	Alpha beta hydrolase
CVV72_01965	COG1131	(ABC) transporter
CVV72_01975	COG2197	response regulator
CVV72_01990	COG2318	DinB family
CVV72_02010	COG0789	Transcriptional regulator
CVV72_02050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CVV72_02055	COG0463	Glycosyl transferase, family 2
CVV72_02060	COG2195	Cleaves the N-terminal amino acid of tripeptides
CVV72_02070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CVV72_02075	COG3795	YCII-related domain
CVV72_02080	COG4941	Belongs to the sigma-70 factor family
CVV72_02085	COG1349	DNA-binding transcription factor activity
CVV72_02120	COG3903	Transcriptional regulator
CVV72_02120	COG3629	intracellular signal transduction
CVV72_02130	COG2197	response regulator
CVV72_02155	COG3237	CsbD-like
CVV72_02175	COG1396	sequence-specific DNA binding
CVV72_02180	COG0740	serine-type endopeptidase activity
CVV72_02185	COG0740	serine-type endopeptidase activity
CVV72_02190	COG0515	serine threonine protein kinase
CVV72_02200	COG0726	polysaccharide deacetylase
CVV72_02205	COG1902	pentaerythritol trinitrate reductase activity
CVV72_02215	COG1278	Cold shock
CVV72_02220	COG1846	Transcriptional regulator
CVV72_02245	COG0559	Belongs to the binding-protein-dependent transport system permease family
CVV72_02300	COG3845	ABC transporter
CVV72_02315	COG1309	transcriptional regulator
CVV72_02355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVV72_02380	COG0583	DNA-binding transcription factor activity
CVV72_02415	COG2066	Belongs to the glutaminase family
CVV72_02435	COG2188	Transcriptional regulator
CVV72_02450	COG0531	amino acid
CVV72_02475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CVV72_02495	COG1175	transmembrane transport
CVV72_02500	COG0395	ABC-type sugar transport system, permease component
CVV72_02505	COG3842	ATPase activity
CVV72_02515	COG1349	DNA-binding transcription factor activity
CVV72_02520	COG1501	Belongs to the glycosyl hydrolase 31 family
CVV72_02525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CVV72_02545	COG0187	DNA topoisomerase II activity
CVV72_02585	COG0583	DNA-binding transcription factor activity
CVV72_02620	COG1653	transport
CVV72_02635	COG1511	domain protein
CVV72_02655	COG2226	methyltransferase
CVV72_02660	COG0539	negative regulation of cytoplasmic translation
CVV72_02670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CVV72_02670	COG0237	dephospho-CoA kinase activity
CVV72_02705	COG1024	Enoyl-CoA hydratase
CVV72_02720	COG1131	(ABC) transporter
CVV72_02730	COG4946	Tricorn protease homolog
CVV72_02730	COG0823	Involved in the tonB-independent uptake of proteins
CVV72_02730	COG1506	peptidase
CVV72_02745	COG1609	Transcriptional regulator
CVV72_02750	COG1070	Carbohydrate kinase
CVV72_02795	COG3250	beta-galactosidase activity
CVV72_02800	COG3012	SEC-C Motif Domain Protein
CVV72_02885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVV72_02930	COG1733	regulation of RNA biosynthetic process
CVV72_02940	COG1301	dicarboxylic acid transport
CVV72_02945	COG3290	protein histidine kinase activity
CVV72_02950	COG4565	transcriptional regulatory protein
CVV72_02995	COG0395	ABC-type sugar transport system, permease component
CVV72_03000	COG1175	transmembrane transport
CVV72_03010	COG2706	6-phosphogluconolactonase activity
CVV72_03015	COG2610	gluconate transmembrane transporter activity
CVV72_03020	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CVV72_03040	COG0251	oxidation-reduction process
CVV72_03045	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CVV72_03050	COG1802	Transcriptional regulator
CVV72_03065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CVV72_03070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CVV72_03075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVV72_03080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CVV72_03085	COG0072	phenylalanine-tRNA ligase activity
CVV72_03085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVV72_03120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CVV72_03125	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CVV72_03130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CVV72_03135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CVV72_03145	COG1438	arginine binding
CVV72_03150	COG0137	argininosuccinate synthase activity
CVV72_03155	COG0165	Argininosuccinate lyase
CVV72_03165	COG2094	Belongs to the DNA glycosylase MPG family
CVV72_03170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CVV72_03195	COG0647	UMP catabolic process
CVV72_03210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CVV72_03240	COG1953	Uracil, thiamine, allantoin
CVV72_03245	COG1802	Transcriptional regulator
CVV72_03255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CVV72_03260	COG0504	CTP synthase activity
CVV72_03265	COG0494	nUDIX hydrolase
CVV72_03295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CVV72_03305	COG2936	dipeptidyl-peptidase activity
CVV72_03320	COG1309	transcriptional regulator
CVV72_03325	COG0475	glutathione-regulated potassium exporter activity
CVV72_03355	COG1160	GTP binding
CVV72_03375	COG3848	Pyruvate phosphate dikinase
CVV72_03375	COG0574	Belongs to the PEP-utilizing enzyme family
CVV72_03395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CVV72_03405	COG0154	amidase activity
CVV72_03420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVV72_03425	COG1414	Transcriptional regulator
CVV72_03435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVV72_03440	COG4948	Mandelate Racemase Muconate Lactonizing
CVV72_03455	COG5492	domain, Protein
CVV72_03460	COG0596	Alpha beta hydrolase
CVV72_03470	COG0583	DNA-binding transcription factor activity
CVV72_03495	COG2124	cytochrome p450
CVV72_03505	COG5001	Diguanylate cyclase
CVV72_03525	COG4981	capsule polysaccharide biosynthetic process
CVV72_03590	COG4991	sh3 domain protein
CVV72_03620	COG0596	Alpha beta hydrolase
CVV72_03625	COG3629	intracellular signal transduction
CVV72_03625	COG3903	Transcriptional regulator
CVV72_03640	COG2188	Transcriptional regulator
CVV72_03655	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CVV72_03660	COG1403	HNH endonuclease
CVV72_03675	COG0028	Belongs to the TPP enzyme family
CVV72_03680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CVV72_03695	COG2315	Protein conserved in bacteria
CVV72_03700	COG4585	Histidine kinase
CVV72_03705	COG2197	response regulator
CVV72_03710	COG3903	Transcriptional regulator
CVV72_03710	COG3629	intracellular signal transduction
CVV72_03720	COG1309	transcriptional regulator
CVV72_03725	COG2409	Drug exporters of the RND superfamily
CVV72_03750	COG4106	trans-aconitate 2-methyltransferase activity
CVV72_03775	COG1064	alcohol dehydrogenase
CVV72_03785	COG1309	transcriptional regulator
CVV72_03790	COG1132	(ABC) transporter
CVV72_03810	COG1063	alcohol dehydrogenase
CVV72_03860	COG0477	Major facilitator Superfamily
CVV72_03875	COG1960	acyl-CoA dehydrogenase activity
CVV72_03885	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CVV72_03890	COG2301	Belongs to the HpcH HpaI aldolase family
CVV72_03900	COG1309	transcriptional regulator
CVV72_03910	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_03915	COG2072	flavoprotein involved in K transport
CVV72_03930	COG2197	response regulator
CVV72_03985	COG1309	transcriptional regulator
CVV72_03995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVV72_03995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVV72_04015	COG0583	DNA-binding transcription factor activity
CVV72_04075	COG2318	DinB family
CVV72_04080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CVV72_04080	COG2755	lipolytic protein G-D-S-L family
CVV72_04085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CVV72_04100	COG1335	isochorismatase
CVV72_04110	COG3511	phospholipase C
CVV72_04130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CVV72_04135	COG1414	Transcriptional regulator
CVV72_04145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CVV72_04150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CVV72_04155	COG2271	Major facilitator Superfamily
CVV72_04170	COG1959	2 iron, 2 sulfur cluster binding
CVV72_04185	COG0702	epimerase
CVV72_04200	COG3226	Transcriptional regulator
CVV72_04205	COG0667	Aldo Keto reductase
CVV72_04210	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_04215	COG0604	alcohol dehydrogenase
CVV72_04215	COG3321	synthase
CVV72_04225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CVV72_04260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CVV72_04285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CVV72_04360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVV72_04360	COG0515	serine threonine protein kinase
CVV72_04365	COG0515	serine threonine protein kinase
CVV72_04365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVV72_04390	COG0477	Major facilitator Superfamily
CVV72_04395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVV72_04395	COG3321	synthase
CVV72_04400	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_04415	COG0300	oxidoreductase activity
CVV72_04420	COG1819	glycosyl
CVV72_04445	COG4251	negative regulation of phosphorylation
CVV72_04450	COG0784	Response regulator, receiver
CVV72_04465	COG0515	serine threonine protein kinase
CVV72_04465	COG2815	serine threonine protein kinase
CVV72_04475	COG0488	(ABC) transporter
CVV72_04490	COG0488	(ABC) transporter
CVV72_04500	COG0706	membrane insertase activity
CVV72_04505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CVV72_04515	COG1522	sequence-specific DNA binding
CVV72_04570	COG1733	regulation of RNA biosynthetic process
CVV72_04580	COG0778	Nitroreductase
CVV72_04600	COG2309	aminopeptidase activity
CVV72_04605	COG3473	Maleate cis-trans isomerase
CVV72_04615	COG0477	Major facilitator Superfamily
CVV72_04640	COG1335	isochorismatase
CVV72_04650	COG0686	Belongs to the AlaDH PNT family
CVV72_04655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_04660	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CVV72_04695	COG1414	Transcriptional regulator
CVV72_04705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CVV72_04715	COG2855	membrane
CVV72_04725	COG1113	amino acid transport
CVV72_04730	COG0427	acetyl-CoA hydrolase
CVV72_04735	COG0667	Aldo Keto reductase
CVV72_04745	COG0477	Major facilitator Superfamily
CVV72_04750	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_04760	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CVV72_04795	COG0367	asparagine synthase
CVV72_04815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CVV72_04820	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CVV72_04835	COG0789	Transcriptional regulator
CVV72_04865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CVV72_04870	COG0798	PFAM Bile acid sodium symporter
CVV72_04875	COG2072	flavoprotein involved in K transport
CVV72_04880	COG3321	synthase
CVV72_04880	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_04880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVV72_04880	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_04880	COG0300	oxidoreductase activity
CVV72_04885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVV72_04885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVV72_04895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVV72_04925	COG0640	Transcriptional regulator
CVV72_04985	COG2326	polyphosphate kinase activity
CVV72_05015	COG1470	cell adhesion involved in biofilm formation
CVV72_05020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CVV72_05040	COG0517	IMP dehydrogenase activity
CVV72_05040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CVV72_05040	COG0617	tRNA 3'-terminal CCA addition
CVV72_05050	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CVV72_05060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CVV72_05105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CVV72_05105	COG0517	IMP dehydrogenase activity
CVV72_05105	COG0617	tRNA 3'-terminal CCA addition
CVV72_05110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVV72_05110	COG1042	CoA-binding domain protein
CVV72_05110	COG0045	succinate-CoA ligase (ADP-forming) activity
CVV72_05165	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CVV72_05190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVV72_05240	COG0517	IMP dehydrogenase activity
CVV72_05240	COG0516	GMP reductase activity
CVV72_05245	COG2217	Heavy metal translocating P-type atpase
CVV72_05260	COG0574	Belongs to the PEP-utilizing enzyme family
CVV72_05260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CVV72_05265	COG1131	(ABC) transporter
CVV72_05270	COG3559	Exporter of polyketide antibiotics
CVV72_05275	COG0516	GMP reductase activity
CVV72_05275	COG0517	IMP dehydrogenase activity
CVV72_05300	COG0549	Belongs to the carbamate kinase family
CVV72_05305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CVV72_05315	COG0531	amino acid
CVV72_05335	COG1131	(ABC) transporter
CVV72_05350	COG1937	Protein conserved in bacteria
CVV72_05390	COG0438	transferase activity, transferring glycosyl groups
CVV72_05405	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVV72_05405	COG0022	dehydrogenase e1 component
CVV72_05410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CVV72_05415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CVV72_05430	COG1830	Aldolase
CVV72_05505	COG0543	2 iron, 2 sulfur cluster binding
CVV72_05520	COG0309	Hydrogenase expression formation protein (HypE)
CVV72_05525	COG0409	Hydrogenase expression formation protein
CVV72_05530	COG0298	carbon dioxide binding
CVV72_05555	COG1017	nitric oxide dioxygenase activity
CVV72_05555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVV72_05570	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CVV72_05575	COG1140	nitrate reductase beta subunit
CVV72_05590	COG2197	response regulator
CVV72_05595	COG1404	Belongs to the peptidase S8 family
CVV72_05680	COG2197	response regulator
CVV72_05755	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CVV72_05825	COG0596	Alpha beta hydrolase
CVV72_05830	COG2208	phosphoserine phosphatase activity
CVV72_05840	COG1366	Belongs to the anti-sigma-factor antagonist family
CVV72_05845	COG2508	Transcriptional regulator
CVV72_05845	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CVV72_05885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVV72_05885	COG0515	serine threonine protein kinase
CVV72_05900	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CVV72_05905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CVV72_05910	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CVV72_05925	COG0587	DNA-directed DNA polymerase activity
CVV72_06000	COG0778	Nitroreductase
CVV72_06005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CVV72_06030	COG1560	Kdo2-lipid A biosynthetic process
CVV72_06035	COG0438	transferase activity, transferring glycosyl groups
CVV72_06045	COG3608	succinylglutamate desuccinylase aspartoacylase
CVV72_06045	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CVV72_06055	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CVV72_06090	COG1309	transcriptional regulator
CVV72_06100	COG1396	sequence-specific DNA binding
CVV72_06115	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CVV72_06120	COG0217	transcriptional regulatory protein
CVV72_06135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CVV72_06140	COG0632	four-way junction helicase activity
CVV72_06145	COG2255	four-way junction helicase activity
CVV72_06160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVV72_06165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CVV72_06170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CVV72_06185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CVV72_06190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CVV72_06225	COG3903	Transcriptional regulator
CVV72_06225	COG3629	intracellular signal transduction
CVV72_06275	COG2018	Roadblock/LC7 domain
CVV72_06295	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CVV72_06315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CVV72_06340	COG1280	lysine exporter protein (LysE YggA)
CVV72_06360	COG0596	Alpha beta hydrolase
CVV72_06365	COG3622	Belongs to the hyi family
CVV72_06370	COG2084	Dehydrogenase
CVV72_06375	COG3960	tartronate-semialdehyde synthase activity
CVV72_06395	COG2366	antibiotic biosynthetic process
CVV72_06405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CVV72_06440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CVV72_06445	COG1522	sequence-specific DNA binding
CVV72_06465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CVV72_06505	COG2201	protein-glutamate methylesterase activity
CVV72_06550	COG4977	sequence-specific DNA binding
CVV72_06560	COG2197	response regulator
CVV72_06565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CVV72_06570	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_06590	COG0302	gtp cyclohydrolase
CVV72_06600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CVV72_06610	COG1733	regulation of RNA biosynthetic process
CVV72_06615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CVV72_06615	COG2124	cytochrome p450
CVV72_06630	COG2226	methyltransferase
CVV72_06645	COG0488	(ABC) transporter
CVV72_06660	COG0395	ABC-type sugar transport system, permease component
CVV72_06680	COG1609	Transcriptional regulator
CVV72_06685	COG1879	ABC-type sugar transport system periplasmic component
CVV72_06695	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVV72_06700	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVV72_06715	COG2160	L-arabinose isomerase activity
CVV72_06720	COG4213	ABC transporter substrate-binding protein
CVV72_06725	COG1129	ABC transporter
CVV72_06730	COG4214	carbohydrate transport
CVV72_06740	COG3940	Belongs to the glycosyl hydrolase 43 family
CVV72_06745	COG3250	beta-galactosidase activity
CVV72_06785	COG3971	2-oxopent-4-enoate hydratase activity
CVV72_06795	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_06810	COG0477	Major facilitator Superfamily
CVV72_06840	COG2226	methyltransferase
CVV72_06840	COG1073	alpha beta
CVV72_06845	COG0537	adenosine 5'-monophosphoramidase activity
CVV72_06850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CVV72_06860	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CVV72_06885	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVV72_06930	COG2409	Drug exporters of the RND superfamily
CVV72_06935	COG1846	Transcriptional regulator
CVV72_06940	COG0702	epimerase
CVV72_06945	COG5297	Belongs to the glycosyl hydrolase family 6
CVV72_06950	COG0745	RESPONSE REGULATOR receiver
CVV72_06955	COG5002	protein histidine kinase activity
CVV72_06965	COG2814	Major facilitator Superfamily
CVV72_06975	COG1733	regulation of RNA biosynthetic process
CVV72_07005	COG1175	transmembrane transport
CVV72_07010	COG0395	ABC-type sugar transport system, permease component
CVV72_07020	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CVV72_07035	COG4948	Mandelate Racemase Muconate Lactonizing
CVV72_07040	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CVV72_07040	COG2508	Transcriptional regulator
CVV72_07075	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CVV72_07100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVV72_07105	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_07115	COG4638	Rieske (2fe-2S)
CVV72_07145	COG0154	amidase activity
CVV72_07150	COG4566	intracellular signal transduction
CVV72_07160	COG0477	Major facilitator Superfamily
CVV72_07165	COG0154	amidase activity
CVV72_07170	COG1136	(ABC) transporter
CVV72_07210	COG2197	response regulator
CVV72_07215	COG4585	Histidine kinase
CVV72_07220	COG1609	Transcriptional regulator
CVV72_07230	COG1129	ABC transporter
CVV72_07235	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVV72_07240	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVV72_07270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_07295	COG0477	Major facilitator Superfamily
CVV72_07305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CVV72_07325	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVV72_07355	COG1940	carbohydrate kinase activity
CVV72_07360	COG2115	Belongs to the xylose isomerase family
CVV72_07410	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_07470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CVV72_07475	COG3404	Formiminotransferase-cyclodeaminase
CVV72_07505	COG3546	catalase activity
CVV72_07515	COG1295	ribonuclease BN
CVV72_07560	COG2755	lipolytic protein G-D-S-L family
CVV72_07560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CVV72_07570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVV72_07600	COG0667	Aldo Keto reductase
CVV72_07605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_07610	COG1968	undecaprenyl-diphosphatase activity
CVV72_07620	COG0339	signal peptide processing
CVV72_07625	COG1104	cysteine desulfurase activity
CVV72_07630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_07660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CVV72_07685	COG0039	L-malate dehydrogenase activity
CVV72_07720	COG1595	DNA-templated transcription, initiation
CVV72_07725	COG0477	Major facilitator Superfamily
CVV72_07730	COG3537	Alpha-1,2-mannosidase
CVV72_07740	COG1136	(ABC) transporter
CVV72_07745	COG1136	(ABC) transporter
CVV72_07765	COG2084	Dehydrogenase
CVV72_07775	COG0697	spore germination
CVV72_07795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CVV72_07805	COG1309	transcriptional regulator
CVV72_07815	COG2226	methyltransferase
CVV72_07830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVV72_07835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVV72_07835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVV72_07840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CVV72_07870	COG0604	alcohol dehydrogenase
CVV72_07870	COG3321	synthase
CVV72_07880	COG0025	NhaP-type Na H and K H
CVV72_07935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CVV72_07940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVV72_07945	COG2124	cytochrome p450
CVV72_07980	COG0492	ferredoxin-NADP+ reductase activity
CVV72_07995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CVV72_08000	COG0709	Synthesizes selenophosphate from selenide and ATP
CVV72_08015	COG2072	flavoprotein involved in K transport
CVV72_08020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CVV72_08030	COG3639	organic phosphonate transmembrane transporter activity
CVV72_08035	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CVV72_08040	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CVV72_08050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CVV72_08065	COG1819	glycosyl
CVV72_08070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CVV72_08090	COG1509	lysine 2,3-aminomutase activity
CVV72_08095	COG1228	amidohydrolase
CVV72_08105	COG0463	Glycosyl transferase, family 2
CVV72_08125	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_08135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVV72_08145	COG1435	thymidine kinase activity
CVV72_08175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CVV72_08180	COG0640	Transcriptional regulator
CVV72_08200	COG2226	methyltransferase
CVV72_08205	COG2226	methyltransferase
CVV72_08210	COG2890	protein-(glutamine-N5) methyltransferase activity
CVV72_08220	COG2318	DinB family
CVV72_08225	COG1595	DNA-templated transcription, initiation
CVV72_08235	COG1309	transcriptional regulator
CVV72_08240	COG1960	acyl-CoA dehydrogenase activity
CVV72_08260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CVV72_08300	COG4941	Belongs to the sigma-70 factor family
CVV72_08335	COG1357	PFAM Pentapeptide repeats (8 copies)
CVV72_08345	COG2755	lipolytic protein G-D-S-L family
CVV72_08380	COG2226	methyltransferase
CVV72_08390	COG0596	Alpha beta hydrolase
CVV72_08425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVV72_08435	COG1522	sequence-specific DNA binding
CVV72_08445	COG0590	tRNA wobble adenosine to inosine editing
CVV72_08450	COG4974	Belongs to the 'phage' integrase family
CVV72_08485	COG0583	DNA-binding transcription factor activity
CVV72_08490	COG1846	Transcriptional regulator
CVV72_08495	COG0596	Alpha beta hydrolase
CVV72_08500	COG1309	transcriptional regulator
CVV72_08570	COG1404	Belongs to the peptidase S8 family
CVV72_08630	COG0387	Pfam Sodium calcium exchanger
CVV72_08635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CVV72_08640	COG2124	cytochrome p450
CVV72_08655	COG1472	Belongs to the glycosyl hydrolase 3 family
CVV72_08660	COG1472	Belongs to the glycosyl hydrolase 3 family
CVV72_08665	COG1609	Transcriptional regulator
CVV72_08670	COG1501	Belongs to the glycosyl hydrolase 31 family
CVV72_08675	COG0395	ABC-type sugar transport system, permease component
CVV72_08695	COG0583	DNA-binding transcription factor activity
CVV72_08705	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
CVV72_08720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CVV72_08725	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CVV72_08770	COG0589	response to stress
CVV72_08780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CVV72_08785	COG1522	sequence-specific DNA binding
CVV72_08805	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CVV72_08805	COG2508	Transcriptional regulator
CVV72_08810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVV72_08815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVV72_08830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CVV72_08835	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CVV72_08840	COG2080	2 iron, 2 sulfur cluster binding
CVV72_08850	COG1309	transcriptional regulator
CVV72_08870	COG0028	Belongs to the TPP enzyme family
CVV72_08895	COG0024	Methionine aminopeptidase
CVV72_08915	COG1136	(ABC) transporter
CVV72_08915	COG4591	ABC-type transport system involved in lipoprotein release permease component
CVV72_08930	COG2197	response regulator
CVV72_08955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CVV72_08980	COG0640	Transcriptional regulator
CVV72_08995	COG0477	Major facilitator Superfamily
CVV72_09045	COG1619	proteins homologs of microcin C7 resistance protein MccF
CVV72_09075	COG0601	transmembrane transport
CVV72_09125	COG0183	Belongs to the thiolase family
CVV72_09140	COG1595	DNA-templated transcription, initiation
CVV72_09150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CVV72_09160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_09170	COG0488	(ABC) transporter
CVV72_09180	COG2362	D-Aminopeptidase
CVV72_09185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVV72_09260	COG4552	Acetyltransferase involved in intracellular survival and related
CVV72_09295	COG1597	lipid kinase activity
CVV72_09305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CVV72_09315	COG2378	regulation of single-species biofilm formation
CVV72_09325	COG1733	regulation of RNA biosynthetic process
CVV72_09330	COG0604	alcohol dehydrogenase
CVV72_09350	COG0640	Transcriptional regulator
CVV72_09360	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CVV72_09365	COG1597	lipid kinase activity
CVV72_09370	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CVV72_09375	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CVV72_09415	COG1222	aaa ATPase
CVV72_09435	COG0517	IMP dehydrogenase activity
CVV72_09435	COG1994	Peptidase M50
CVV72_09450	COG1192	Involved in chromosome partitioning
CVV72_09455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CVV72_09460	COG0140	phosphoribosyl-ATP diphosphatase activity
CVV72_09475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVV72_09485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CVV72_09490	COG2814	Major facilitator Superfamily
CVV72_09505	COG0488	(ABC) transporter
CVV72_09510	COG0215	cysteine-tRNA ligase activity
CVV72_09515	COG0789	Transcriptional regulator
CVV72_09540	COG0596	Alpha beta hydrolase
CVV72_09545	COG3226	Transcriptional regulator
CVV72_09550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CVV72_09570	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CVV72_09580	COG0477	Major facilitator Superfamily
CVV72_09585	COG0745	RESPONSE REGULATOR receiver
CVV72_09590	COG2205	protein histidine kinase activity
CVV72_09610	COG3540	Alkaline phosphatase
CVV72_09615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CVV72_09620	COG2304	oxidoreductase activity
CVV72_09630	COG0714	Associated with various cellular activities
CVV72_09635	COG0746	molybdenum cofactor guanylyltransferase activity
CVV72_09640	COG3883	PFAM NLP P60 protein
CVV72_09640	COG0791	NLP P60 protein
CVV72_09645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CVV72_09660	COG1285	pathogenesis
CVV72_09670	COG0477	Major facilitator Superfamily
CVV72_09695	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CVV72_09700	COG0121	glutamine amidotransferase
CVV72_09705	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CVV72_09710	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CVV72_09715	COG0583	DNA-binding transcription factor activity
CVV72_09720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CVV72_09725	COG2267	carboxylic ester hydrolase activity
CVV72_09775	COG0656	L-ascorbic acid biosynthetic process
CVV72_09790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CVV72_09790	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CVV72_09815	COG1716	ATPase activity
CVV72_09820	COG0509	glycine decarboxylation via glycine cleavage system
CVV72_09880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CVV72_09885	COG1024	Enoyl-CoA hydratase
CVV72_09900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CVV72_09900	COG1648	precorrin-2 dehydrogenase activity
CVV72_09915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CVV72_09920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CVV72_09925	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CVV72_09935	COG0254	rRNA binding
CVV72_09945	COG0523	cobalamin synthesis protein
CVV72_09955	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_09970	COG0640	Transcriptional regulator
CVV72_10000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_10025	COG1414	Transcriptional regulator
CVV72_10035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVV72_10050	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVV72_10055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVV72_10060	COG1132	(ABC) transporter
CVV72_10065	COG1132	(ABC) transporter
CVV72_10070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CVV72_10080	COG3251	PFAM MbtH domain protein
CVV72_10095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CVV72_10105	COG1653	transport
CVV72_10115	COG0395	ABC-type sugar transport system, permease component
CVV72_10120	COG0488	(ABC) transporter
CVV72_10130	COG1024	Enoyl-CoA hydratase
CVV72_10140	COG1595	DNA-templated transcription, initiation
CVV72_10245	COG1793	dna ligase
CVV72_10245	COG3285	dna ligase
CVV72_10250	COG3903	Transcriptional regulator
CVV72_10250	COG3629	intracellular signal transduction
CVV72_10260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CVV72_10265	COG3629	intracellular signal transduction
CVV72_10265	COG3903	Transcriptional regulator
CVV72_10415	COG0542	response to heat
CVV72_10430	COG0085	RNA polymerase activity
CVV72_10625	COG0210	DNA helicase
CVV72_10635	COG0542	response to heat
CVV72_10715	COG1266	CAAX protease self-immunity
CVV72_10860	COG2815	serine threonine protein kinase
CVV72_10860	COG0515	serine threonine protein kinase
CVV72_10880	COG3285	dna ligase
CVV72_10880	COG1793	dna ligase
CVV72_10900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CVV72_10905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CVV72_10910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CVV72_10930	COG0242	peptide deformylase activity
CVV72_11110	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CVV72_11150	COG2188	Transcriptional regulator
CVV72_11170	COG2909	trisaccharide binding
CVV72_11205	COG0587	DNA-directed DNA polymerase activity
CVV72_11225	COG2124	cytochrome p450
CVV72_11235	COG3903	Transcriptional regulator
CVV72_11235	COG3629	intracellular signal transduction
CVV72_11240	COG2226	methyltransferase
CVV72_11255	COG1129	ABC transporter
CVV72_11330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CVV72_11370	COG3903	Transcriptional regulator
CVV72_11370	COG3629	intracellular signal transduction
CVV72_11450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CVV72_11460	COG0791	NLP P60 protein
CVV72_11460	COG1388	LysM domain
CVV72_11460	COG3103	Sh3 type 3 domain protein
CVV72_11500	COG0477	Major facilitator Superfamily
CVV72_11510	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CVV72_11520	COG3938	Belongs to the proline racemase family
CVV72_11525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVV72_11550	COG0006	proline dipeptidase activity
CVV72_11555	COG0583	DNA-binding transcription factor activity
CVV72_11580	COG1366	Belongs to the anti-sigma-factor antagonist family
CVV72_11600	COG4585	Histidine kinase
CVV72_11620	COG0129	dihydroxy-acid dehydratase activity
CVV72_11625	COG1253	flavin adenine dinucleotide binding
CVV72_11650	COG4977	sequence-specific DNA binding
CVV72_11715	COG0657	acetylesterase activity
CVV72_11730	COG0747	negative chemotaxis
CVV72_11735	COG0601	transmembrane transport
CVV72_11755	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_11785	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_11790	COG1802	Transcriptional regulator
CVV72_11795	COG5504	Zn-dependent protease
CVV72_11805	COG0701	Predicted permease
CVV72_11870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVV72_11885	COG1120	ATPase activity
CVV72_11890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVV72_11895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVV72_11900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CVV72_11905	COG2375	cellular response to nickel ion
CVV72_11910	COG3433	isochorismatase activity
CVV72_11910	COG1535	isochorismatase
CVV72_11915	COG1535	isochorismatase
CVV72_11915	COG3433	isochorismatase activity
CVV72_11920	COG1021	2,3-dihydroxybenzoate-AMP ligase
CVV72_11925	COG1169	isochorismate synthase
CVV72_11930	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_11940	COG2205	protein histidine kinase activity
CVV72_11945	COG0745	RESPONSE REGULATOR receiver
CVV72_11955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CVV72_11970	COG4977	sequence-specific DNA binding
CVV72_11980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CVV72_11980	COG0825	malonyl-CoA metabolic process
CVV72_11985	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_11995	COG2186	Transcriptional regulator
CVV72_12000	COG1309	transcriptional regulator
CVV72_12015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_12030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CVV72_12035	COG1414	Transcriptional regulator
CVV72_12055	COG1082	Xylose isomerase domain protein TIM barrel
CVV72_12055	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CVV72_12060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CVV72_12070	COG0477	Major facilitator Superfamily
CVV72_12090	COG1609	Transcriptional regulator
CVV72_12100	COG1175	transmembrane transport
CVV72_12110	COG0366	Alpha amylase catalytic
CVV72_12115	COG3629	intracellular signal transduction
CVV72_12115	COG3903	Transcriptional regulator
CVV72_12120	COG1764	response to oxidative stress
CVV72_12150	COG0583	DNA-binding transcription factor activity
CVV72_12175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CVV72_12185	COG4209	transmembrane transport
CVV72_12190	COG0395	ABC-type sugar transport system, permease component
CVV72_12205	COG1609	Transcriptional regulator
CVV72_12230	COG1609	Transcriptional regulator
CVV72_12255	COG1403	HNH endonuclease
CVV72_12275	COG0277	FAD linked oxidase domain protein
CVV72_12305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CVV72_12330	COG3226	Transcriptional regulator
CVV72_12350	COG0714	Associated with various cellular activities
CVV72_12355	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CVV72_12395	COG0673	inositol 2-dehydrogenase activity
CVV72_12405	COG3415	Transposase
CVV72_12405	COG2801	Transposase and inactivated derivatives
CVV72_12465	COG2814	Major facilitator Superfamily
CVV72_12500	COG0583	DNA-binding transcription factor activity
CVV72_12510	COG2132	Multicopper oxidase
CVV72_12540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CVV72_12550	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_12565	COG2326	polyphosphate kinase activity
CVV72_12650	COG2197	response regulator
CVV72_12665	COG0583	DNA-binding transcription factor activity
CVV72_12680	COG1917	Cupin 2, conserved barrel domain protein
CVV72_12680	COG4977	sequence-specific DNA binding
CVV72_12690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVV72_12715	COG0596	Alpha beta hydrolase
CVV72_12735	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CVV72_12740	COG0477	Major facilitator Superfamily
CVV72_12745	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_12750	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CVV72_12765	COG1960	acyl-CoA dehydrogenase activity
CVV72_12785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_12800	COG3903	Transcriptional regulator
CVV72_12800	COG3629	intracellular signal transduction
CVV72_12805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CVV72_12875	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_12890	COG0739	heme binding
CVV72_12905	COG3540	Alkaline phosphatase
CVV72_12930	COG4585	Histidine kinase
CVV72_12955	COG0596	Alpha beta hydrolase
CVV72_12975	COG1051	belongs to the nudix hydrolase family
CVV72_13000	COG3973	AAA domain
CVV72_13030	COG2197	response regulator
CVV72_13035	COG4585	Histidine kinase
CVV72_13045	COG0531	amino acid
CVV72_13050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CVV72_13070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVV72_13075	COG0297	glycogen (starch) synthase activity
CVV72_13080	COG2124	cytochrome p450
CVV72_13095	COG0736	holo-[acyl-carrier-protein] synthase activity
CVV72_13115	COG1309	transcriptional regulator
CVV72_13160	COG2850	peptidyl-arginine hydroxylation
CVV72_13190	COG0142	geranyltranstransferase activity
CVV72_13215	COG2226	methyltransferase
CVV72_13230	COG3046	protein related to deoxyribodipyrimidine photolyase
CVV72_13250	COG3903	Transcriptional regulator
CVV72_13250	COG3629	intracellular signal transduction
CVV72_13265	COG2197	response regulator
CVV72_13280	COG2197	response regulator
CVV72_13285	COG2197	response regulator
CVV72_13300	COG2226	methyltransferase
CVV72_13390	COG1222	aaa ATPase
CVV72_13420	COG0596	Alpha beta hydrolase
CVV72_13430	COG0531	amino acid
CVV72_13455	COG4977	sequence-specific DNA binding
CVV72_13465	COG0456	acetyltransferase
CVV72_13470	COG2356	endonuclease I
CVV72_13530	COG1335	isochorismatase
CVV72_13575	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CVV72_13610	COG3629	intracellular signal transduction
CVV72_13610	COG3903	Transcriptional regulator
CVV72_13645	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CVV72_13665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CVV72_13670	COG0723	plastoquinol--plastocyanin reductase activity
CVV72_13675	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CVV72_13690	COG2890	protein-(glutamine-N5) methyltransferase activity
CVV72_13705	COG0438	transferase activity, transferring glycosyl groups
CVV72_13725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVV72_13730	COG2192	nodulation
CVV72_13735	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CVV72_13740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CVV72_13740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CVV72_13745	COG0300	oxidoreductase activity
CVV72_13755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CVV72_13825	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_13835	COG0475	glutathione-regulated potassium exporter activity
CVV72_13840	COG1834	amidinotransferase
CVV72_13845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CVV72_13880	COG0069	glutamate synthase activity
CVV72_13885	COG0017	Asparaginyl-tRNA synthetase
CVV72_13915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVV72_13915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVV72_13950	COG3655	Transcriptional regulator
CVV72_13960	COG1573	uracil-dna glycosylase
CVV72_13970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_14030	COG0028	Belongs to the TPP enzyme family
CVV72_14035	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_14040	COG1309	transcriptional regulator
CVV72_14045	COG1733	regulation of RNA biosynthetic process
CVV72_14050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVV72_14055	COG3415	Transposase
CVV72_14055	COG2801	Transposase and inactivated derivatives
CVV72_14065	COG2124	cytochrome p450
CVV72_14080	COG1414	Transcriptional regulator
CVV72_14085	COG0154	amidase activity
CVV72_14110	COG1053	succinate dehydrogenase
CVV72_14115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_14140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_14180	COG0697	spore germination
CVV72_14185	COG3903	Transcriptional regulator
CVV72_14185	COG3629	intracellular signal transduction
CVV72_14195	COG3706	GGDEF domain
CVV72_14205	COG0745	RESPONSE REGULATOR receiver
CVV72_14210	COG2205	protein histidine kinase activity
CVV72_14225	COG0328	RNA-DNA hybrid ribonuclease activity
CVV72_14230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CVV72_14260	COG3706	GGDEF domain
CVV72_14275	COG0439	Biotin carboxylase
CVV72_14285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CVV72_14300	COG2855	membrane
CVV72_14305	COG2814	Major facilitator Superfamily
CVV72_14320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVV72_14320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVV72_14325	COG0739	heme binding
CVV72_14345	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CVV72_14365	COG1793	dna ligase
CVV72_14375	COG0477	Major facilitator Superfamily
CVV72_14380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_14395	COG1846	Transcriptional regulator
CVV72_14405	COG0564	pseudouridine synthase activity
CVV72_14430	COG2124	cytochrome p450
CVV72_14450	COG0431	NADPH-dependent FMN reductase
CVV72_14455	COG1940	carbohydrate kinase activity
CVV72_14460	COG0531	amino acid
CVV72_14480	COG0484	heat shock protein binding
CVV72_14495	COG3795	YCII-related domain
CVV72_14500	COG4941	Belongs to the sigma-70 factor family
CVV72_14530	COG0717	Belongs to the dCTP deaminase family
CVV72_14535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CVV72_14555	COG1960	acyl-CoA dehydrogenase activity
CVV72_14560	COG1960	acyl-CoA dehydrogenase activity
CVV72_14565	COG1960	acyl-CoA dehydrogenase activity
CVV72_14575	COG1309	transcriptional regulator
CVV72_14595	COG2091	lysine biosynthetic process via aminoadipic acid
CVV72_14610	COG1960	acyl-CoA dehydrogenase activity
CVV72_14620	COG1250	3-hydroxyacyl-CoA dehydrogenase
CVV72_14635	COG3321	synthase
CVV72_14635	COG0604	alcohol dehydrogenase
CVV72_14640	COG3321	synthase
CVV72_14640	COG3321	synthase
CVV72_14640	COG0604	alcohol dehydrogenase
CVV72_14640	COG0604	alcohol dehydrogenase
CVV72_14665	COG3321	synthase
CVV72_14665	COG0604	alcohol dehydrogenase
CVV72_14675	COG3321	synthase
CVV72_14675	COG0604	alcohol dehydrogenase
CVV72_14695	COG0477	Major facilitator Superfamily
CVV72_14735	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_14740	COG1309	transcriptional regulator
CVV72_14745	COG0477	Major facilitator Superfamily
CVV72_14765	COG3469	chitinase activity
CVV72_14790	COG1309	transcriptional regulator
CVV72_14810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CVV72_14815	COG1960	acyl-CoA dehydrogenase activity
CVV72_14845	COG1024	Enoyl-CoA hydratase
CVV72_14855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVV72_14855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CVV72_14860	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVV72_14865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CVV72_14890	COG1316	TRANSCRIPTIONal
CVV72_14895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CVV72_14900	COG2267	carboxylic ester hydrolase activity
CVV72_14905	COG4821	SIS domain
CVV72_14915	COG1132	(ABC) transporter
CVV72_14930	COG0488	(ABC) transporter
CVV72_14945	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CVV72_14955	COG2199	diguanylate cyclase activity
CVV72_14955	COG2200	EAL domain
CVV72_14965	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_14985	COG0175	sulfate reduction
CVV72_14995	COG2197	response regulator
CVV72_15000	COG4585	Histidine kinase
CVV72_15015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CVV72_15025	COG1742	UPF0060 membrane protein
CVV72_15030	COG2151	metal-sulfur cluster biosynthetic enzyme
CVV72_15045	COG0396	ATPase activity
CVV72_15080	COG1612	heme a metabolic process
CVV72_15130	COG0109	protoheme IX farnesyltransferase activity
CVV72_15140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CVV72_15145	COG0166	Belongs to the GPI family
CVV72_15160	COG0363	glucosamine-6-phosphate deaminase activity
CVV72_15180	COG0149	triose-phosphate isomerase activity
CVV72_15185	COG0126	phosphoglycerate kinase activity
CVV72_15190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CVV72_15245	COG3250	beta-galactosidase activity
CVV72_15250	COG1309	transcriptional regulator
CVV72_15260	COG0463	Glycosyl transferase, family 2
CVV72_15265	COG1481	regulation of sporulation
CVV72_15275	COG1660	Displays ATPase and GTPase activities
CVV72_15280	COG0322	excinuclease ABC activity
CVV72_15300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CVV72_15305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CVV72_15305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CVV72_15320	COG4585	Histidine kinase
CVV72_15325	COG2197	response regulator
CVV72_15345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CVV72_15350	COG0405	Gamma-glutamyltransferase
CVV72_15360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CVV72_15365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CVV72_15375	COG1758	RNA polymerase activity
CVV72_15380	COG0194	GDP metabolic process
CVV72_15390	COG0284	orotidine-5'-phosphate decarboxylase activity
CVV72_15400	COG0505	Belongs to the CarA family
CVV72_15415	COG0540	Belongs to the ATCase OTCase family
CVV72_15420	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CVV72_15430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CVV72_15435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CVV72_15440	COG0006	proline dipeptidase activity
CVV72_15455	COG0346	lactoylglutathione lyase activity
CVV72_15460	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CVV72_15465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CVV72_15475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CVV72_15480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CVV72_15515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVV72_15520	COG2188	Transcriptional regulator
CVV72_15525	COG1263	PTS System
CVV72_15530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVV72_15540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CVV72_15570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CVV72_15575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CVV72_15590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CVV72_15625	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CVV72_15630	COG0235	Class ii aldolase
CVV72_15635	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CVV72_15640	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CVV72_15650	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CVV72_15655	COG1079	Belongs to the binding-protein-dependent transport system permease family
CVV72_15660	COG4603	Belongs to the binding-protein-dependent transport system permease family
CVV72_15665	COG3845	ABC transporter
CVV72_15710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CVV72_15735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CVV72_15740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CVV72_15750	COG0446	pyridine nucleotide-disulphide oxidoreductase
CVV72_15765	COG2326	polyphosphate kinase activity
CVV72_15770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CVV72_15780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVV72_15790	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CVV72_15835	COG1793	dna ligase
CVV72_15850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CVV72_15855	COG0506	proline dehydrogenase activity
CVV72_15860	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_15865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CVV72_15865	COG2508	Transcriptional regulator
CVV72_15870	COG0539	negative regulation of cytoplasmic translation
CVV72_15875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_15890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVV72_15900	COG2815	serine threonine protein kinase
CVV72_15900	COG0515	serine threonine protein kinase
CVV72_15910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CVV72_15930	COG3220	belongs to the UPF0276 family
CVV72_15940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CVV72_15945	COG3253	May function as heme-dependent peroxidase
CVV72_15955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CVV72_15965	COG2197	response regulator
CVV72_15975	COG1309	transcriptional regulator
CVV72_15990	COG3665	Urea carboxylase-associated protein
CVV72_16015	COG0183	Belongs to the thiolase family
CVV72_16020	COG1024	Enoyl-CoA hydratase
CVV72_16020	COG1250	3-hydroxyacyl-CoA dehydrogenase
CVV72_16035	COG0656	L-ascorbic acid biosynthetic process
CVV72_16040	COG2205	protein histidine kinase activity
CVV72_16045	COG0745	RESPONSE REGULATOR receiver
CVV72_16060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVV72_16075	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_16085	COG0300	oxidoreductase activity
CVV72_16090	COG1309	transcriptional regulator
CVV72_16095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CVV72_16100	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_16125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVV72_16130	COG0531	amino acid
CVV72_16135	COG0569	domain protein
CVV72_16165	COG0756	dUTP diphosphatase activity
CVV72_16185	COG0483	inositol monophosphate 1-phosphatase activity
CVV72_16240	COG2197	response regulator
CVV72_16245	COG0531	amino acid
CVV72_16285	COG4214	carbohydrate transport
CVV72_16295	COG4213	ABC transporter substrate-binding protein
CVV72_16310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVV72_16335	COG2313	pseudouridylate synthase activity
CVV72_16355	COG2890	protein-(glutamine-N5) methyltransferase activity
CVV72_16360	COG1490	D-aminoacyl-tRNA deacylase activity
CVV72_16370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CVV72_16370	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CVV72_16405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVV72_16410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVV72_16415	COG2188	Transcriptional regulator
CVV72_16425	COG2070	2-Nitropropane dioxygenase
CVV72_16435	COG1024	Enoyl-CoA hydratase
CVV72_16465	COG1295	ribonuclease BN
CVV72_16475	COG2124	cytochrome p450
CVV72_16480	COG0183	Belongs to the thiolase family
CVV72_16500	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_16505	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_16510	COG1024	Enoyl-CoA hydratase
CVV72_16530	COG0596	Alpha beta hydrolase
CVV72_16545	COG0110	maltose O-acetyltransferase activity
CVV72_16585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVV72_16595	COG2814	Major facilitator Superfamily
CVV72_16600	COG0183	Belongs to the thiolase family
CVV72_16605	COG1309	transcriptional regulator
CVV72_16610	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_16615	COG1960	acyl-CoA dehydrogenase activity
CVV72_16620	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_16625	COG1024	Enoyl-CoA hydratase
CVV72_16630	COG1960	acyl-CoA dehydrogenase activity
CVV72_16635	COG1960	acyl-CoA dehydrogenase activity
CVV72_16640	COG1960	acyl-CoA dehydrogenase activity
CVV72_16680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CVV72_16685	COG0346	lactoylglutathione lyase activity
CVV72_16690	COG2267	carboxylic ester hydrolase activity
CVV72_16695	COG1960	acyl-CoA dehydrogenase activity
CVV72_16705	COG1053	succinate dehydrogenase
CVV72_16725	COG2030	dehydratase
CVV72_16735	COG0196	riboflavin kinase activity
CVV72_16745	COG0183	Belongs to the thiolase family
CVV72_16760	COG1960	acyl-CoA dehydrogenase activity
CVV72_16765	COG1960	acyl-CoA dehydrogenase activity
CVV72_16775	COG0657	acetylesterase activity
CVV72_16785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CVV72_16790	COG1960	acyl-CoA dehydrogenase activity
CVV72_16795	COG1309	transcriptional regulator
CVV72_16800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_16810	COG1703	isobutyryl-CoA mutase activity
CVV72_16810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CVV72_16810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CVV72_16825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CVV72_16840	COG2018	Roadblock/LC7 domain
CVV72_16855	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVV72_16860	COG1309	transcriptional regulator
CVV72_16870	COG2814	Major facilitator Superfamily
CVV72_16875	COG1566	PFAM secretion protein HlyD family protein
CVV72_16900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CVV72_16905	COG1960	acyl-CoA dehydrogenase activity
CVV72_16920	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_16925	COG1672	PFAM Archaeal ATPase
CVV72_16925	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CVV72_16945	COG1946	Acyl-CoA thioesterase
CVV72_16980	COG1228	amidohydrolase
CVV72_16990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVV72_17015	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CVV72_17025	COG1940	carbohydrate kinase activity
CVV72_17035	COG0003	Pfam Anion-transporting ATPase
CVV72_17075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_17090	COG0577	efflux transmembrane transporter activity
CVV72_17090	COG1136	(ABC) transporter
CVV72_17140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CVV72_17145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CVV72_17155	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_17165	COG1960	acyl-CoA dehydrogenase activity
CVV72_17170	COG1960	acyl-CoA dehydrogenase activity
CVV72_17175	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_17185	COG1132	(ABC) transporter
CVV72_17210	COG1309	transcriptional regulator
CVV72_17225	COG0123	including yeast histone deacetylase and acetoin utilization protein
CVV72_17240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CVV72_17260	COG2936	dipeptidyl-peptidase activity
CVV72_17280	COG0628	permease
CVV72_17295	COG3387	PFAM Glycoside hydrolase 15-related
CVV72_17315	COG1505	serine-type exopeptidase activity
CVV72_17325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CVV72_17370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVV72_17375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CVV72_17385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CVV72_17400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CVV72_17420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CVV72_17430	COG1196	nuclear chromosome segregation
CVV72_17445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CVV72_17455	COG2205	protein histidine kinase activity
CVV72_17460	COG0745	RESPONSE REGULATOR receiver
CVV72_17465	COG1126	abc transporter atp-binding protein
CVV72_17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVV72_17475	COG0765	amino acid transport
CVV72_17480	COG0765	amino acid transport
CVV72_17485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CVV72_17500	COG1053	succinate dehydrogenase
CVV72_17520	COG0800	Aldolase
CVV72_17540	COG2137	regulation of response to DNA damage stimulus
CVV72_17545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CVV72_17555	COG0443	Heat shock 70 kDa protein
CVV72_17560	COG1201	RNA secondary structure unwinding
CVV72_17565	COG0242	peptide deformylase activity
CVV72_17600	COG0697	spore germination
CVV72_17635	COG0142	geranyltranstransferase activity
CVV72_17650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_17670	COG0515	serine threonine protein kinase
CVV72_17670	COG2815	serine threonine protein kinase
CVV72_17680	COG0702	epimerase
CVV72_17690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CVV72_17695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CVV72_17700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CVV72_17710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CVV72_17715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CVV72_17730	COG0768	penicillin binding
CVV72_17740	COG0275	rRNA processing
CVV72_17745	COG2001	Belongs to the MraZ family
CVV72_17770	COG0714	Associated with various cellular activities
CVV72_17780	COG1305	Transglutaminase-like
CVV72_17790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CVV72_17800	COG1192	Involved in chromosome partitioning
CVV72_17805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CVV72_17810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CVV72_17820	COG0167	dihydroorotate dehydrogenase activity
CVV72_17825	COG0154	amidase activity
CVV72_17835	COG1842	Phage shock protein A
CVV72_17850	COG1396	sequence-specific DNA binding
CVV72_17855	COG1058	Belongs to the CinA family
CVV72_17855	COG1546	Belongs to the CinA family
CVV72_17865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CVV72_17870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CVV72_17880	COG0596	Alpha beta hydrolase
CVV72_17895	COG1674	ftsk spoiiie
CVV72_17905	COG0655	NAD(P)H dehydrogenase (quinone) activity
CVV72_17935	COG1113	amino acid transport
CVV72_17950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CVV72_17955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVV72_17960	COG0515	serine threonine protein kinase
CVV72_17985	COG3214	Protein conserved in bacteria
CVV72_18015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CVV72_18025	COG1185	polyribonucleotide nucleotidyltransferase activity
CVV72_18030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CVV72_18050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CVV72_18070	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CVV72_18070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVV72_18120	COG0779	Required for maturation of 30S ribosomal subunits
CVV72_18160	COG1733	regulation of RNA biosynthetic process
CVV72_18175	COG2936	dipeptidyl-peptidase activity
CVV72_18185	COG0745	RESPONSE REGULATOR receiver
CVV72_18190	COG5002	protein histidine kinase activity
CVV72_18195	COG0583	DNA-binding transcription factor activity
CVV72_18200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CVV72_18205	COG1024	Enoyl-CoA hydratase
CVV72_18215	COG1250	3-hydroxyacyl-CoA dehydrogenase
CVV72_18220	COG1960	acyl-CoA dehydrogenase activity
CVV72_18235	COG1316	TRANSCRIPTIONal
CVV72_18265	COG0477	Major facilitator Superfamily
CVV72_18270	COG0789	Transcriptional regulator
CVV72_18360	COG3850	Histidine kinase
CVV72_18360	COG5002	protein histidine kinase activity
CVV72_18375	COG0702	epimerase
CVV72_18450	COG3903	Transcriptional regulator
CVV72_18450	COG3629	intracellular signal transduction
CVV72_18490	COG2072	flavoprotein involved in K transport
CVV72_18495	COG2508	Transcriptional regulator
CVV72_18510	COG3647	Membrane
CVV72_18515	COG0531	amino acid
CVV72_18535	COG3903	Transcriptional regulator
CVV72_18535	COG3629	intracellular signal transduction
CVV72_18590	COG4106	trans-aconitate 2-methyltransferase activity
CVV72_18605	COG1595	DNA-templated transcription, initiation
CVV72_18610	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CVV72_18630	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CVV72_18640	COG2197	response regulator
CVV72_18645	COG4585	Histidine kinase
CVV72_18655	COG1131	(ABC) transporter
CVV72_18660	COG0423	glycine-tRNA ligase activity
CVV72_18695	COG0701	Predicted permease
CVV72_18705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CVV72_18710	COG1381	Involved in DNA repair and RecF pathway recombination
CVV72_18745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CVV72_18760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CVV72_18770	COG0537	adenosine 5'-monophosphoramidase activity
CVV72_18780	COG0484	heat shock protein binding
CVV72_18785	COG1420	regulation of RNA biosynthetic process
CVV72_18820	COG2205	protein histidine kinase activity
CVV72_18825	COG0745	RESPONSE REGULATOR receiver
CVV72_18830	COG1953	Uracil, thiamine, allantoin
CVV72_18840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CVV72_18850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVV72_18910	COG0463	Glycosyl transferase, family 2
CVV72_18920	COG2192	nodulation
CVV72_18960	COG0175	sulfate reduction
CVV72_18990	COG2732	(Barnase) inhibitor
CVV72_19005	COG0604	alcohol dehydrogenase
CVV72_19015	COG0531	amino acid
CVV72_19020	COG2070	2-Nitropropane dioxygenase
CVV72_19040	COG2226	methyltransferase
CVV72_19055	COG0268	Binds directly to 16S ribosomal RNA
CVV72_19070	COG0658	competence protein
CVV72_19070	COG2333	competence protein COMEC
CVV72_19075	COG1555	photosystem II stabilization
CVV72_19080	COG1307	EDD domain protein, DegV family
CVV72_19090	COG0406	alpha-ribazole phosphatase activity
CVV72_19095	COG0799	negative regulation of ribosome biogenesis
CVV72_19100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CVV72_19110	COG0477	Major facilitator Superfamily
CVV72_19115	COG0018	arginyl-trna synthetase
CVV72_19130	COG1595	DNA-templated transcription, initiation
CVV72_19145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CVV72_19150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CVV72_19155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CVV72_19160	COG1530	ribonuclease E activity
CVV72_19170	COG0842	Transport permease protein
CVV72_19180	COG1131	(ABC) transporter
CVV72_19205	COG0105	UTP biosynthetic process
CVV72_19210	COG1733	regulation of RNA biosynthetic process
CVV72_19225	COG2366	antibiotic biosynthetic process
CVV72_19235	COG0285	dihydrofolate synthase activity
CVV72_19250	COG0525	valine-tRNA ligase activity
CVV72_19265	COG1316	TRANSCRIPTIONal
CVV72_19270	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_19280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CVV72_19310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CVV72_19315	COG0740	serine-type endopeptidase activity
CVV72_19325	COG0544	peptidyl-prolyl cis-trans isomerase activity
CVV72_19330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVV72_19335	COG2205	protein histidine kinase activity
CVV72_19340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CVV72_19350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CVV72_19380	COG1846	Transcriptional regulator
CVV72_19385	COG2814	Major facilitator Superfamily
CVV72_19395	COG0501	Belongs to the peptidase M48B family
CVV72_19410	COG0515	serine threonine protein kinase
CVV72_19410	COG2815	serine threonine protein kinase
CVV72_19420	COG0693	protein deglycase activity
CVV72_19435	COG5002	protein histidine kinase activity
CVV72_19435	COG0784	Response regulator, receiver
CVV72_19475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CVV72_19490	COG4941	Belongs to the sigma-70 factor family
CVV72_19500	COG3345	alpha-galactosidase
CVV72_19525	COG0698	ribose 5-phosphate isomerase
CVV72_19540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CVV72_19550	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CVV72_19570	COG0668	transmembrane transport
CVV72_19580	COG0366	Alpha amylase catalytic
CVV72_19610	COG2902	Dehydrogenase
CVV72_19655	COG1609	Transcriptional regulator
CVV72_19690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CVV72_19705	COG1733	regulation of RNA biosynthetic process
CVV72_19715	COG1113	amino acid transport
CVV72_19725	COG1846	Transcriptional regulator
CVV72_19735	COG3285	dna ligase
CVV72_19735	COG1793	dna ligase
CVV72_19740	COG3285	dna ligase
CVV72_19740	COG1793	dna ligase
CVV72_19780	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CVV72_19785	COG2197	response regulator
CVV72_19790	COG1917	Cupin 2, conserved barrel domain protein
CVV72_19790	COG4977	sequence-specific DNA binding
CVV72_19800	COG2197	response regulator
CVV72_19810	COG1733	regulation of RNA biosynthetic process
CVV72_19815	COG0009	L-threonylcarbamoyladenylate synthase
CVV72_19825	COG2197	response regulator
CVV72_19845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVV72_19870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CVV72_19905	COG2124	cytochrome p450
CVV72_19925	COG1917	Cupin 2, conserved barrel domain protein
CVV72_19925	COG4977	sequence-specific DNA binding
CVV72_19945	COG1733	regulation of RNA biosynthetic process
CVV72_19970	COG3795	YCII-related domain
CVV72_19975	COG1937	Protein conserved in bacteria
CVV72_20010	COG2267	carboxylic ester hydrolase activity
CVV72_20015	COG4221	oxidoreductase activity
CVV72_20025	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CVV72_20045	COG0745	RESPONSE REGULATOR receiver
CVV72_20050	COG2205	protein histidine kinase activity
CVV72_20085	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_20120	COG0581	inorganic phosphate transmembrane transporter activity
CVV72_20125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CVV72_20135	COG0604	alcohol dehydrogenase
CVV72_20135	COG3321	synthase
CVV72_20150	COG0596	Alpha beta hydrolase
CVV72_20245	COG1609	Transcriptional regulator
CVV72_20260	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CVV72_20265	COG0745	RESPONSE REGULATOR receiver
CVV72_20275	COG1136	(ABC) transporter
CVV72_20280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CVV72_20285	COG2205	protein histidine kinase activity
CVV72_20355	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_20360	COG1024	Enoyl-CoA hydratase
CVV72_20405	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_20415	COG1643	Atp-dependent helicase
CVV72_20425	COG0475	glutathione-regulated potassium exporter activity
CVV72_20450	COG3268	Saccharopine dehydrogenase
CVV72_20455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CVV72_20455	COG1796	DNA polymerase
CVV72_20465	COG1802	Transcriptional regulator
CVV72_20485	COG3706	GGDEF domain
CVV72_20490	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CVV72_20495	COG0010	Belongs to the arginase family
CVV72_20515	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CVV72_20530	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CVV72_20530	COG0235	Class ii aldolase
CVV72_20560	COG1309	transcriptional regulator
CVV72_20585	COG0247	lactate metabolic process
CVV72_20585	COG0277	FAD linked oxidase domain protein
CVV72_20595	COG2197	response regulator
CVV72_20610	COG0559	Belongs to the binding-protein-dependent transport system permease family
CVV72_20615	COG0559	Belongs to the binding-protein-dependent transport system permease family
CVV72_20630	COG1522	sequence-specific DNA binding
CVV72_20645	COG1739	Uncharacterized protein family UPF0029
CVV72_20650	COG0070	glutamate synthase
CVV72_20650	COG0069	glutamate synthase activity
CVV72_20650	COG0067	glutamate synthase
CVV72_20675	COG2197	response regulator
CVV72_20680	COG4585	Histidine kinase
CVV72_20690	COG1131	(ABC) transporter
CVV72_20705	COG1492	cobalamin metabolic process
CVV72_20710	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CVV72_20720	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CVV72_20725	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CVV72_20745	COG1797	cobyrinic acid a,c-diamide synthase activity
CVV72_20785	COG3973	AAA domain
CVV72_20805	COG1131	(ABC) transporter
CVV72_20815	COG1476	TRANSCRIPTIONal
CVV72_20825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CVV72_20825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CVV72_20835	COG0488	(ABC) transporter
CVV72_20840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVV72_20845	COG2151	metal-sulfur cluster biosynthetic enzyme
CVV72_20850	COG3396	Phenylacetate-CoA oxygenase
CVV72_20855	COG3460	Phenylacetate-CoA oxygenase
CVV72_20860	COG3396	Phenylacetate-CoA oxygenase
CVV72_20865	COG2030	dehydratase
CVV72_20865	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_20880	COG1309	transcriptional regulator
CVV72_20910	COG2072	flavoprotein involved in K transport
CVV72_20925	COG2183	response to ionizing radiation
CVV72_20940	COG0513	Belongs to the DEAD box helicase family
CVV72_20950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CVV72_20955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CVV72_20970	COG4585	Histidine kinase
CVV72_20975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CVV72_20980	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CVV72_20990	COG3540	Alkaline phosphatase
CVV72_20995	COG4991	sh3 domain protein
CVV72_21000	COG3903	Transcriptional regulator
CVV72_21000	COG3629	intracellular signal transduction
CVV72_21005	COG4991	sh3 domain protein
CVV72_21070	COG1131	(ABC) transporter
CVV72_21090	COG1126	abc transporter atp-binding protein
CVV72_21095	COG0765	amino acid transport
CVV72_21100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVV72_21140	COG4251	negative regulation of phosphorylation
CVV72_21140	COG2203	Gaf domain
CVV72_21140	COG3706	GGDEF domain
CVV72_21140	COG5001	Diguanylate cyclase
CVV72_21150	COG2124	cytochrome p450
CVV72_21195	COG2304	oxidoreductase activity
CVV72_21360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVV72_21445	COG0667	Aldo Keto reductase
CVV72_21455	COG1733	regulation of RNA biosynthetic process
CVV72_21460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVV72_21465	COG1024	Enoyl-CoA hydratase
CVV72_21470	COG1024	Enoyl-CoA hydratase
CVV72_21475	COG1024	Enoyl-CoA hydratase
CVV72_21545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CVV72_21560	COG2226	methyltransferase
CVV72_21570	COG1819	glycosyl
CVV72_21575	COG1819	glycosyl
CVV72_21580	COG2124	cytochrome p450
CVV72_21585	COG2124	cytochrome p450
CVV72_21590	COG2124	cytochrome p450
CVV72_21595	COG2124	cytochrome p450
CVV72_21625	COG1132	(ABC) transporter
CVV72_21640	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CVV72_21645	COG1181	Belongs to the D-alanine--D-alanine ligase family
CVV72_21715	COG0300	oxidoreductase activity
CVV72_21755	COG2124	cytochrome p450
CVV72_21760	COG3511	phospholipase C
CVV72_21770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVV72_21815	COG1132	(ABC) transporter
CVV72_21815	COG2375	cellular response to nickel ion
CVV72_21820	COG1132	(ABC) transporter
CVV72_21825	COG4552	Acetyltransferase involved in intracellular survival and related
CVV72_21850	COG2207	Transcriptional regulator
CVV72_21855	COG5650	phosphatidylinositol metabolic process
CVV72_21905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CVV72_21950	COG3291	Pkd domain containing protein
CVV72_21970	COG0084	hydrolase, TatD family'
CVV72_21980	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CVV72_21990	COG0673	inositol 2-dehydrogenase activity
CVV72_22000	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVV72_22005	COG1129	ABC transporter
CVV72_22015	COG1940	carbohydrate kinase activity
CVV72_22030	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CVV72_22035	COG4565	transcriptional regulatory protein
CVV72_22040	COG3290	protein histidine kinase activity
CVV72_22125	COG2255	four-way junction helicase activity
CVV72_22145	COG0247	lactate metabolic process
CVV72_22145	COG2181	nitrate reductase activity
CVV72_22155	COG1121	(ABC) transporter
CVV72_22160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CVV72_22165	COG1120	ATPase activity
CVV72_22180	COG0326	Molecular chaperone. Has ATPase activity
CVV72_22200	COG3835	regulator
CVV72_22215	COG0596	Alpha beta hydrolase
CVV72_22245	COG1309	transcriptional regulator
CVV72_22265	COG2182	Extracellular solute-binding protein
CVV72_22270	COG1175	transmembrane transport
CVV72_22275	COG0395	ABC-type sugar transport system, permease component
CVV72_22280	COG1472	Belongs to the glycosyl hydrolase 3 family
CVV72_22290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_22295	COG2084	Dehydrogenase
CVV72_22305	COG0438	transferase activity, transferring glycosyl groups
CVV72_22310	COG0483	inositol monophosphate 1-phosphatase activity
CVV72_22320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CVV72_22335	COG0297	glycogen (starch) synthase activity
CVV72_22355	COG1942	4-Oxalocrotonate Tautomerase
CVV72_22370	COG5001	Diguanylate cyclase
CVV72_22395	COG1793	dna ligase
CVV72_22395	COG3285	dna ligase
CVV72_22435	COG0667	Aldo Keto reductase
CVV72_22460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_22475	COG0187	DNA topoisomerase II activity
CVV72_22485	COG1960	acyl-CoA dehydrogenase activity
CVV72_22490	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_22495	COG2030	dehydratase
CVV72_22505	COG0183	Belongs to the thiolase family
CVV72_22510	COG0473	3-isopropylmalate dehydrogenase activity
CVV72_22510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CVV72_22520	COG0583	DNA-binding transcription factor activity
CVV72_22535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVV72_22540	COG1643	Atp-dependent helicase
CVV72_22550	COG1131	(ABC) transporter
CVV72_22575	COG2197	response regulator
CVV72_22580	COG4585	Histidine kinase
CVV72_22595	COG1228	amidohydrolase
CVV72_22600	COG0402	S-adenosylhomocysteine deaminase activity
CVV72_22610	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CVV72_22615	COG2986	histidine ammonia-lyase
CVV72_22640	COG4585	Histidine kinase
CVV72_22645	COG2197	response regulator
CVV72_22665	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CVV72_22670	COG2177	Part of the ABC transporter FtsEX involved in
CVV72_22675	COG2884	Cell division ATP-binding protein ftsE
CVV72_22680	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CVV72_22710	COG1615	UPF0182 protein
CVV72_22720	COG3480	Lon protease (S16) C-terminal proteolytic domain
CVV72_22740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CVV72_22795	COG0174	glutamine synthetase
CVV72_22805	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CVV72_22815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CVV72_22815	COG0519	Catalyzes the synthesis of GMP from XMP
CVV72_22825	COG1522	sequence-specific DNA binding
CVV72_22845	COG0154	amidase activity
CVV72_22850	COG0174	glutamine synthetase
CVV72_22875	COG0653	protein targeting
CVV72_22880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CVV72_22880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CVV72_22895	COG2318	DinB family
CVV72_22900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CVV72_22900	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CVV72_22905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CVV72_22915	COG0596	Alpha beta hydrolase
CVV72_22920	COG1177	transmembrane transport
CVV72_22925	COG1176	ABC-type spermidine putrescine transport system, permease component I
CVV72_22930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CVV72_22935	COG3842	ATPase activity
CVV72_22940	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_22965	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_22970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CVV72_23085	COG2197	response regulator
CVV72_23110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CVV72_23140	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CVV72_23150	COG3265	gluconokinase activity
CVV72_23160	COG0640	Transcriptional regulator
CVV72_23175	COG1486	melibiose metabolic process
CVV72_23180	COG0395	ABC-type sugar transport system, permease component
CVV72_23185	COG1175	transmembrane transport
CVV72_23200	COG1309	transcriptional regulator
CVV72_23220	COG0612	Peptidase, M16
CVV72_23270	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CVV72_23275	COG0714	Associated with various cellular activities
CVV72_23320	COG0210	DNA helicase
CVV72_23335	COG4585	Histidine kinase
CVV72_23345	COG2378	regulation of single-species biofilm formation
CVV72_23360	COG0745	RESPONSE REGULATOR receiver
CVV72_23365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CVV72_23365	COG2146	nitrite reductase [NAD(P)H] activity
CVV72_23370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CVV72_23370	COG2146	nitrite reductase [NAD(P)H] activity
CVV72_23375	COG2223	nitrite transmembrane transporter activity
CVV72_23380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CVV72_23385	COG0243	molybdopterin cofactor binding
CVV72_23395	COG1136	(ABC) transporter
CVV72_23425	COG0596	Alpha beta hydrolase
CVV72_23435	COG0402	S-adenosylhomocysteine deaminase activity
CVV72_23445	COG2267	carboxylic ester hydrolase activity
CVV72_23480	COG0513	Belongs to the DEAD box helicase family
CVV72_23505	COG2095	MarC family integral membrane protein
CVV72_23510	COG0613	PHP domain protein
CVV72_23540	COG0598	Magnesium transport protein CorA
CVV72_23560	COG1309	transcriptional regulator
CVV72_23625	COG0330	HflC and HflK could
CVV72_23635	COG2239	Acts as a magnesium transporter
CVV72_23650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CVV72_23655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CVV72_23670	COG1595	DNA-templated transcription, initiation
CVV72_23680	COG2814	Major facilitator Superfamily
CVV72_23685	COG0583	DNA-binding transcription factor activity
CVV72_23690	COG0671	phosphoesterase, PA-phosphatase related
CVV72_23695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CVV72_23705	COG1024	Enoyl-CoA hydratase
CVV72_23710	COG0519	Catalyzes the synthesis of GMP from XMP
CVV72_23745	COG1271	oxidase subunit
CVV72_23750	COG1294	oxidase, subunit
CVV72_23755	COG4988	ABC transporter
CVV72_23760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CVV72_23765	COG0463	Glycosyl transferase, family 2
CVV72_23780	COG1611	Belongs to the LOG family
CVV72_23825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVV72_23835	COG2171	N-acyltransferase activity
CVV72_23875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CVV72_23880	COG0778	Nitroreductase
CVV72_23880	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CVV72_23895	COG1725	Transcriptional regulator
CVV72_23940	COG0438	transferase activity, transferring glycosyl groups
CVV72_23970	COG1316	TRANSCRIPTIONal
CVV72_23975	COG1316	TRANSCRIPTIONal
CVV72_23985	COG2259	Doxx family
CVV72_24005	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_24010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CVV72_24050	COG0477	Major facilitator Superfamily
CVV72_24065	COG2197	response regulator
CVV72_24080	COG2205	protein histidine kinase activity
CVV72_24085	COG0745	RESPONSE REGULATOR receiver
CVV72_24090	COG0483	inositol monophosphate 1-phosphatase activity
CVV72_24115	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CVV72_24115	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CVV72_24120	COG1388	LysM domain
CVV72_24120	COG0791	NLP P60 protein
CVV72_24120	COG3103	Sh3 type 3 domain protein
CVV72_24175	COG0640	Transcriptional regulator
CVV72_24190	COG2249	NAD(P)H dehydrogenase (quinone) activity
CVV72_24195	COG4585	Histidine kinase
CVV72_24200	COG2197	response regulator
CVV72_24205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CVV72_24240	COG1472	Belongs to the glycosyl hydrolase 3 family
CVV72_24245	COG0424	maF-like protein
CVV72_24250	COG1301	dicarboxylic acid transport
CVV72_24265	COG4770	biotin carboxylase activity
CVV72_24295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CVV72_24300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CVV72_24305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CVV72_24335	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CVV72_24335	COG1473	amidohydrolase
CVV72_24360	COG0515	serine threonine protein kinase
CVV72_24390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CVV72_24415	COG1228	amidohydrolase
CVV72_24430	COG0667	Aldo Keto reductase
CVV72_24435	COG0667	Aldo Keto reductase
CVV72_24480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CVV72_24485	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_24490	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_24510	COG0395	ABC-type sugar transport system, permease component
CVV72_24525	COG1063	alcohol dehydrogenase
CVV72_24535	COG1733	regulation of RNA biosynthetic process
CVV72_24560	COG2271	Major facilitator Superfamily
CVV72_24565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CVV72_24585	COG1079	Belongs to the binding-protein-dependent transport system permease family
CVV72_24595	COG3845	ABC transporter
CVV72_24600	COG1744	ABC transporter substrate-binding protein PnrA-like
CVV72_24605	COG2009	succinate dehydrogenase
CVV72_24620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CVV72_24635	COG1404	Belongs to the peptidase S8 family
CVV72_24645	COG1686	Belongs to the peptidase S11 family
CVV72_24650	COG1295	ribonuclease BN
CVV72_24655	COG0180	Tryptophanyl-tRNA synthetase
CVV72_24700	COG1234	tRNA 3'-trailer cleavage
CVV72_24725	COG2264	protein methyltransferase activity
CVV72_24735	COG1522	sequence-specific DNA binding
CVV72_24745	COG0667	Aldo Keto reductase
CVV72_24755	COG0583	DNA-binding transcription factor activity
CVV72_24790	COG2814	Major facilitator Superfamily
CVV72_24795	COG0640	Transcriptional regulator
CVV72_24800	COG2814	Major facilitator Superfamily
CVV72_24830	COG1185	polyribonucleotide nucleotidyltransferase activity
CVV72_24835	COG0587	DNA-directed DNA polymerase activity
CVV72_24880	COG0138	bifunctional purine biosynthesis protein purh
CVV72_24905	COG0045	succinate-CoA ligase (ADP-forming) activity
CVV72_24920	COG0739	heme binding
CVV72_24955	COG0515	serine threonine protein kinase
CVV72_24960	COG0515	serine threonine protein kinase
CVV72_24970	COG0583	DNA-binding transcription factor activity
CVV72_25010	COG0519	Catalyzes the synthesis of GMP from XMP
CVV72_25010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CVV72_25030	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_25035	COG0277	FAD linked oxidase domain protein
CVV72_25075	COG0516	GMP reductase activity
CVV72_25125	COG0459	protein refolding
CVV72_25130	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CVV72_25135	COG0546	phosphoglycolate phosphatase activity
CVV72_25145	COG1215	transferase activity, transferring glycosyl groups
CVV72_25165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CVV72_25170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CVV72_25175	COG0456	acetyltransferase
CVV72_25185	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_25190	COG0825	malonyl-CoA metabolic process
CVV72_25190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CVV72_25195	COG0802	atpase or kinase
CVV72_25205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CVV72_25210	COG3842	ATPase activity
CVV72_25215	COG1070	Carbohydrate kinase
CVV72_25220	COG1349	DNA-binding transcription factor activity
CVV72_25230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CVV72_25255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CVV72_25285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CVV72_25290	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CVV72_25295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CVV72_25325	COG0443	Heat shock 70 kDa protein
CVV72_25330	COG1674	ftsk spoiiie
CVV72_25340	COG1404	Belongs to the peptidase S8 family
CVV72_25380	COG0101	tRNA pseudouridine synthase activity
CVV72_25385	COG0203	ribosomal protein L17
CVV72_25390	COG0202	RNA polymerase activity
CVV72_25395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CVV72_25400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CVV72_25415	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CVV72_25420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CVV72_25430	COG0563	adenylate kinase activity
CVV72_25450	COG0200	Binds to the 23S rRNA
CVV72_25455	COG1841	ribosomal large subunit assembly
CVV72_25460	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CVV72_25465	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CVV72_25470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CVV72_25475	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CVV72_25485	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CVV72_25490	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CVV72_25495	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CVV72_25500	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CVV72_25505	COG0255	Belongs to the universal ribosomal protein uL29 family
CVV72_25515	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CVV72_25520	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CVV72_25525	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CVV72_25530	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CVV72_25535	COG0089	rRNA binding
CVV72_25540	COG0088	Forms part of the polypeptide exit tunnel
CVV72_25545	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CVV72_25550	COG0051	transcription antitermination factor activity, RNA binding
CVV72_25560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CVV72_25565	COG0049	tRNA binding
CVV72_25570	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CVV72_25635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CVV72_25660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CVV72_25685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CVV72_25720	COG0081	regulation of translation
CVV72_25745	COG0436	Aminotransferase
CVV72_25770	COG2030	dehydratase
CVV72_25775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CVV72_25805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CVV72_25825	COG0586	Pfam SNARE associated Golgi protein
CVV72_25830	COG4585	Histidine kinase
CVV72_25835	COG2197	response regulator
CVV72_25840	COG0640	Transcriptional regulator
CVV72_25845	COG0346	lactoylglutathione lyase activity
CVV72_25895	COG1666	GTP binding
CVV72_25925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_25935	COG0501	Belongs to the peptidase M48B family
CVV72_25965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CVV72_25980	COG4310	Domain of unknown function (DUF2172)
CVV72_25990	COG0463	Glycosyl transferase, family 2
CVV72_25990	COG1216	Glycosyl transferase, family 2
CVV72_26005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CVV72_26060	COG0367	asparagine synthase
CVV72_26080	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CVV72_26100	COG1834	amidinotransferase
CVV72_26105	COG1522	sequence-specific DNA binding
CVV72_26115	COG0674	pyruvate-flavodoxin oxidoreductase activity
CVV72_26115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CVV72_26120	COG1013	pyruvate-flavodoxin oxidoreductase activity
CVV72_26130	COG0142	geranyltranstransferase activity
CVV72_26155	COG1196	nuclear chromosome segregation
CVV72_26195	COG1007	ATP synthesis coupled electron transport
CVV72_26205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CVV72_26210	COG0713	ATP synthesis coupled electron transport
CVV72_26215	COG0839	Belongs to the complex I subunit 6 family
CVV72_26220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVV72_26225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CVV72_26230	COG1034	ATP synthesis coupled electron transport
CVV72_26245	COG0649	NAD binding
CVV72_26250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVV72_26255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVV72_26270	COG2226	methyltransferase
CVV72_26280	COG0438	transferase activity, transferring glycosyl groups
CVV72_26305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CVV72_26310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CVV72_26340	COG1522	sequence-specific DNA binding
CVV72_26360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CVV72_26370	COG0785	Cytochrome C biogenesis protein
CVV72_26380	COG0406	alpha-ribazole phosphatase activity
CVV72_26385	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CVV72_26425	COG1914	H( )-stimulated, divalent metal cation uptake system
CVV72_26435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CVV72_26435	COG1587	Uroporphyrinogen-III synthase
CVV72_26440	COG0181	hydroxymethylbilane synthase activity
CVV72_26445	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CVV72_26450	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CVV72_26470	COG1595	DNA-templated transcription, initiation
CVV72_26505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CVV72_26535	COG5002	protein histidine kinase activity
CVV72_26550	COG0588	phosphoglycerate mutase activity
CVV72_26565	COG0438	transferase activity, transferring glycosyl groups
CVV72_26570	COG2267	carboxylic ester hydrolase activity
CVV72_26580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CVV72_26610	COG2130	NADP-dependent
CVV72_26640	COG2986	histidine ammonia-lyase
CVV72_26665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CVV72_26670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CVV72_26690	COG2733	membrane
CVV72_26710	COG2186	Transcriptional regulator
CVV72_26715	COG2364	Membrane
CVV72_26750	COG3226	Transcriptional regulator
CVV72_26825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CVV72_26895	COG1278	Cold shock
CVV72_26910	COG1595	DNA-templated transcription, initiation
CVV72_26930	COG0515	serine threonine protein kinase
CVV72_26955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVV72_26985	COG2197	response regulator
CVV72_27000	COG0028	Belongs to the TPP enzyme family
CVV72_27015	COG1132	(ABC) transporter
CVV72_27020	COG1132	(ABC) transporter
CVV72_27030	COG0515	serine threonine protein kinase
CVV72_27070	COG4585	Histidine kinase
CVV72_27075	COG2197	response regulator
CVV72_27115	COG1278	Cold shock
CVV72_27120	COG2233	PERMEase
CVV72_27130	COG0402	S-adenosylhomocysteine deaminase activity
CVV72_27160	COG1595	DNA-templated transcription, initiation
CVV72_27245	COG0582	viral genome integration into host DNA
CVV72_27255	COG2318	DinB family
CVV72_27260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CVV72_27295	COG1846	Transcriptional regulator
CVV72_27310	COG0446	pyridine nucleotide-disulphide oxidoreductase
CVV72_27310	COG1902	pentaerythritol trinitrate reductase activity
CVV72_27315	COG0287	Prephenate dehydrogenase
CVV72_27325	COG2175	clavaminate synthase activity
CVV72_27365	COG0702	epimerase
CVV72_27380	COG1131	(ABC) transporter
CVV72_27385	COG3559	Exporter of polyketide antibiotics
CVV72_27420	COG2172	sigma factor antagonist activity
CVV72_27465	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_27470	COG1309	transcriptional regulator
CVV72_27520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CVV72_27545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CVV72_27560	COG2186	Transcriptional regulator
CVV72_27565	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CVV72_27585	COG1522	sequence-specific DNA binding
CVV72_27600	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CVV72_27600	COG1672	PFAM Archaeal ATPase
CVV72_27630	COG3209	COG3209 Rhs family protein
CVV72_27700	COG3795	YCII-related domain
CVV72_27705	COG4941	Belongs to the sigma-70 factor family
CVV72_27730	COG2234	aminopeptidase activity
CVV72_27735	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_27735	COG0604	alcohol dehydrogenase
CVV72_27735	COG3321	synthase
CVV72_27750	COG0596	Alpha beta hydrolase
CVV72_27770	COG1216	Glycosyl transferase, family 2
CVV72_27800	COG1216	Glycosyl transferase, family 2
CVV72_27810	COG0277	FAD linked oxidase domain protein
CVV72_27815	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_27830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CVV72_27835	COG0671	phosphoesterase, PA-phosphatase related
CVV72_27850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_27855	COG0561	phosphatase activity
CVV72_27895	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_27900	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_27915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CVV72_27945	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVV72_27950	COG0438	transferase activity, transferring glycosyl groups
CVV72_27960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CVV72_27985	COG0477	Major facilitator Superfamily
CVV72_28000	COG0579	oxidoreductase
CVV72_28010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CVV72_28015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CVV72_28020	COG0596	Alpha beta hydrolase
CVV72_28025	COG3766	membrane
CVV72_28030	COG0754	glutathionylspermidine amidase activity
CVV72_28065	COG0406	alpha-ribazole phosphatase activity
CVV72_28075	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CVV72_28080	COG1072	(Pantothenic acid kinase))
CVV72_28155	COG4988	ABC transporter
CVV72_28160	COG1294	oxidase, subunit
CVV72_28165	COG1271	oxidase subunit
CVV72_28230	COG2235	arginine
CVV72_28245	COG1191	sigma factor activity
CVV72_28295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVV72_28305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVV72_28330	COG3275	phosphorelay sensor kinase activity
CVV72_28340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CVV72_28390	COG0438	transferase activity, transferring glycosyl groups
CVV72_28390	COG1216	Glycosyl transferase, family 2
CVV72_28410	COG2197	response regulator
CVV72_28415	COG4585	Histidine kinase
CVV72_28420	COG3311	Transcriptional regulator
CVV72_28425	COG1569	PIN domain
CVV72_28440	COG0477	Major facilitator Superfamily
CVV72_28475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CVV72_28485	COG2226	methyltransferase
CVV72_28510	COG1174	glycine betaine transport
CVV72_28520	COG1174	glycine betaine transport
CVV72_28535	COG2372	response to copper ion
CVV72_28535	COG1276	copper resistance
CVV72_28600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CVV72_28605	COG0702	epimerase
CVV72_28625	COG2301	Belongs to the HpcH HpaI aldolase family
CVV72_28645	COG0154	amidase activity
CVV72_28655	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_28665	COG0444	Belongs to the ABC transporter superfamily
CVV72_28670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVV72_28680	COG0747	negative chemotaxis
CVV72_28685	COG2186	Transcriptional regulator
CVV72_28710	COG0626	cystathionine gamma-synthase activity
CVV72_28730	COG1716	ATPase activity
CVV72_28735	COG1716	ATPase activity
CVV72_28750	COG0768	penicillin binding
CVV72_28755	COG0515	serine threonine protein kinase
CVV72_28835	COG3764	Sortase (surface protein transpeptidase)
CVV72_28855	COG0705	Rhomboid family
CVV72_28855	COG0457	Tetratricopeptide repeat
CVV72_28915	COG2203	Gaf domain
CVV72_28915	COG4585	Histidine kinase
CVV72_28920	COG2197	response regulator
CVV72_28930	COG0789	Transcriptional regulator
CVV72_28985	COG0187	DNA topoisomerase II activity
CVV72_28990	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CVV72_28995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CVV72_29000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CVV72_29005	COG0592	DNA-directed DNA polymerase activity
CVV72_29025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CVV72_29030	COG0706	membrane insertase activity
CVV72_29040	COG0357	Ribosomal RNA small subunit methyltransferase G
CVV72_29045	COG1192	Involved in chromosome partitioning
CVV72_29060	COG1181	Belongs to the D-alanine--D-alanine ligase family
CVV72_29065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_29075	COG3409	Peptidoglycan-binding domain 1 protein
CVV72_29075	COG0860	N-Acetylmuramoyl-L-alanine amidase
CVV72_29080	COG0492	ferredoxin-NADP+ reductase activity
CVV72_29080	COG3118	belongs to the thioredoxin family
CVV72_29095	COG1595	DNA-templated transcription, initiation
CVV72_29125	COG0617	tRNA 3'-terminal CCA addition
CVV72_29130	COG4585	Histidine kinase
CVV72_29205	COG0495	leucyl-tRNA aminoacylation
CVV72_29210	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_29245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVV72_29250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CVV72_29255	COG0477	Major facilitator Superfamily
CVV72_29270	COG2197	response regulator
CVV72_29295	COG1940	carbohydrate kinase activity
CVV72_29295	COG1846	Transcriptional regulator
CVV72_29300	COG0738	Major facilitator superfamily
CVV72_29305	COG3384	dioxygenase
CVV72_29335	COG2267	carboxylic ester hydrolase activity
CVV72_29365	COG0359	binds to the 23S rRNA
CVV72_29370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CVV72_29380	COG0360	Binds together with S18 to 16S ribosomal RNA
CVV72_29420	COG1940	carbohydrate kinase activity
CVV72_29425	COG0673	inositol 2-dehydrogenase activity
CVV72_29430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVV72_29435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVV72_29445	COG1695	Transcriptional regulator
CVV72_29455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVV72_29465	COG2814	Major facilitator Superfamily
CVV72_29485	COG2226	methyltransferase
CVV72_29490	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CVV72_29495	COG4221	oxidoreductase activity
CVV72_29500	COG0402	S-adenosylhomocysteine deaminase activity
CVV72_29505	COG2197	response regulator
CVV72_29515	COG1136	(ABC) transporter
CVV72_29525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CVV72_29540	COG1131	(ABC) transporter
CVV72_29570	COG2197	response regulator
CVV72_29575	COG4585	Histidine kinase
CVV72_29595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CVV72_29610	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CVV72_29620	COG4133	protoheme IX ABC transporter activity
CVV72_29670	COG0456	acetyltransferase
CVV72_29680	COG0789	Transcriptional regulator
CVV72_29685	COG0584	glycerophosphoryl diester phosphodiesterase
CVV72_29710	COG0183	Belongs to the thiolase family
CVV72_29715	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_29720	COG2030	dehydratase
CVV72_29725	COG1309	transcriptional regulator
CVV72_29745	COG3030	protein affecting phage T7 exclusion by the F plasmid
CVV72_29765	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVV72_29770	COG0022	dehydrogenase e1 component
CVV72_29780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVV72_29785	COG0596	Alpha beta hydrolase
CVV72_29795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVV72_29800	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVV72_29805	COG1305	Transglutaminase-like
CVV72_29825	COG0765	amino acid transport
CVV72_29880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CVV72_29905	COG1960	acyl-CoA dehydrogenase activity
CVV72_29910	COG2197	response regulator
CVV72_29915	COG3663	DNA glycosylase
CVV72_29935	COG0737	Belongs to the 5'-nucleotidase family
CVV72_29945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVV72_29985	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CVV72_30000	COG0717	Belongs to the dCTP deaminase family
CVV72_30010	COG1846	Transcriptional regulator
CVV72_30015	COG2340	Cysteine-rich secretory protein family
CVV72_30030	COG0247	lactate metabolic process
CVV72_30030	COG2181	nitrate reductase activity
CVV72_30035	COG2076	Multidrug Resistance protein
CVV72_30070	COG0443	Heat shock 70 kDa protein
CVV72_30075	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CVV72_30080	COG0484	heat shock protein binding
CVV72_30085	COG0789	Transcriptional regulator
CVV72_30120	COG0542	response to heat
CVV72_30140	COG1285	pathogenesis
CVV72_30150	COG0577	efflux transmembrane transporter activity
CVV72_30150	COG1136	(ABC) transporter
CVV72_30170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVV72_30175	COG0243	molybdopterin cofactor binding
CVV72_30190	COG1609	Transcriptional regulator
CVV72_30215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVV72_30220	COG1072	(Pantothenic acid kinase))
CVV72_30225	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_30235	COG0586	Pfam SNARE associated Golgi protein
CVV72_30240	COG0477	Major facilitator Superfamily
CVV72_30250	COG3467	pyridoxamine 5'-phosphate
CVV72_30260	COG0477	Major facilitator Superfamily
CVV72_30265	COG0277	FAD linked oxidase domain protein
CVV72_30270	COG0586	Pfam SNARE associated Golgi protein
CVV72_30315	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_30320	COG0667	Aldo Keto reductase
CVV72_30365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_30375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_30380	COG4172	Belongs to the ABC transporter superfamily
CVV72_30385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVV72_30390	COG0601	transmembrane transport
CVV72_30410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CVV72_30425	COG2814	Major facilitator Superfamily
CVV72_30435	COG0584	glycerophosphoryl diester phosphodiesterase
CVV72_30470	COG5280	Phage tail tape measure protein TP901
CVV72_30470	COG3953	SLT domain
CVV72_30485	COG0436	Aminotransferase
CVV72_30525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CVV72_30535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVV72_30540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVV72_30545	COG0765	amino acid transport
CVV72_30550	COG1126	abc transporter atp-binding protein
CVV72_30565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CVV72_30580	COG2311	Membrane
CVV72_30585	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CVV72_30615	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CVV72_30620	COG0047	phosphoribosylformylglycinamidine synthase activity
CVV72_30625	COG1132	(ABC) transporter
CVV72_30630	COG1132	(ABC) transporter
CVV72_30700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CVV72_30725	COG3311	Transcriptional regulator
CVV72_30730	COG1569	PIN domain
CVV72_30760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CVV72_30780	COG1984	allophanate hydrolase subunit 2
CVV72_30790	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CVV72_30820	COG0745	RESPONSE REGULATOR receiver
CVV72_30840	COG0581	inorganic phosphate transmembrane transporter activity
CVV72_30845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CVV72_30850	COG0704	Plays a role in the regulation of phosphate uptake
CVV72_30865	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CVV72_30870	COG0596	Alpha beta hydrolase
CVV72_30925	COG3973	AAA domain
CVV72_30955	COG4702	Belongs to the UPF0303 family
CVV72_30960	COG1473	amidohydrolase
CVV72_30995	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
CVV72_31040	COG0631	protein serine/threonine phosphatase activity
CVV72_31060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CVV72_31060	COG5479	isomerase activity
CVV72_31065	COG1250	3-hydroxyacyl-CoA dehydrogenase
CVV72_31095	COG2197	response regulator
CVV72_31115	COG0745	RESPONSE REGULATOR receiver
CVV72_31120	COG2205	protein histidine kinase activity
CVV72_31125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CVV72_31150	COG0860	N-Acetylmuramoyl-L-alanine amidase
CVV72_31155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CVV72_31160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CVV72_31175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CVV72_31180	COG0463	Glycosyl transferase, family 2
CVV72_31180	COG1216	Glycosyl transferase, family 2
CVV72_31195	COG1216	Glycosyl transferase, family 2
CVV72_31210	COG0747	negative chemotaxis
CVV72_31215	COG0601	transmembrane transport
CVV72_31220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVV72_31230	COG4608	Belongs to the ABC transporter superfamily
CVV72_31245	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_31255	COG0697	spore germination
CVV72_31260	COG0583	DNA-binding transcription factor activity
CVV72_31275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CVV72_31335	COG1690	Belongs to the RtcB family
CVV72_31370	COG1764	response to oxidative stress
CVV72_31380	COG0076	glutamate decarboxylase activity
CVV72_31410	COG1408	metallophosphoesterase
CVV72_31415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVV72_31475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CVV72_31505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CVV72_31510	COG0494	nUDIX hydrolase
CVV72_31525	COG0596	Alpha beta hydrolase
CVV72_31535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CVV72_31540	COG3104	oligopeptide transport
CVV72_31580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CVV72_31590	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CVV72_31600	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_31630	COG0640	Transcriptional regulator
CVV72_31635	COG2814	Major facilitator Superfamily
CVV72_31640	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CVV72_31645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CVV72_31650	COG1737	Transcriptional regulator
CVV72_31655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CVV72_31660	COG3876	Protein conserved in bacteria
CVV72_31665	COG1472	Belongs to the glycosyl hydrolase 3 family
CVV72_31715	COG1205	dead DEAH box helicase
CVV72_31715	COG1111	helicase
CVV72_31720	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CVV72_31745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CVV72_31745	COG1754	DNA topoisomerase type I activity
CVV72_31755	COG0477	Major facilitator Superfamily
CVV72_31810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CVV72_31815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CVV72_31840	COG0657	acetylesterase activity
CVV72_31845	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_31865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CVV72_31870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVV72_31890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CVV72_31900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CVV72_31905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CVV72_31910	COG2027	D-alanyl-D-alanine carboxypeptidase
CVV72_31950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVV72_31955	COG0302	gtp cyclohydrolase
CVV72_31960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CVV72_31975	COG0789	Transcriptional regulator
CVV72_32000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CVV72_32005	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CVV72_32010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CVV72_32015	COG2226	methyltransferase
CVV72_32025	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CVV72_32055	COG0443	Heat shock 70 kDa protein
CVV72_32060	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CVV72_32095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CVV72_32115	COG0596	Alpha beta hydrolase
CVV72_32120	COG3118	belongs to the thioredoxin family
CVV72_32140	COG1953	Uracil, thiamine, allantoin
CVV72_32165	COG1194	a g-specific adenine glycosylase
CVV72_32175	COG1609	Transcriptional regulator
CVV72_32180	COG0803	Belongs to the bacterial solute-binding protein 9 family
CVV72_32185	COG1120	ATPase activity
CVV72_32195	COG4399	Belongs to the UPF0754 family
CVV72_32200	COG4399	Belongs to the UPF0754 family
CVV72_32215	COG1070	Carbohydrate kinase
CVV72_32220	COG2814	Major facilitator Superfamily
CVV72_32225	COG1349	DNA-binding transcription factor activity
CVV72_32235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVV72_32240	COG2376	Dihydroxyacetone kinase
CVV72_32245	COG0698	ribose 5-phosphate isomerase
CVV72_32260	COG0235	Class ii aldolase
CVV72_32285	COG1309	transcriptional regulator
CVV72_32320	COG0215	cysteine-tRNA ligase activity
CVV72_32340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CVV72_32345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CVV72_32350	COG1329	Transcriptional regulator
CVV72_32360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CVV72_32390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CVV72_32440	COG0477	Major facilitator Superfamily
CVV72_32450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CVV72_32450	COG0825	malonyl-CoA metabolic process
CVV72_32455	COG0511	ligase activity, forming carbon-carbon bonds
CVV72_32460	COG0439	Biotin carboxylase
CVV72_32510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CVV72_32540	COG2226	methyltransferase
CVV72_32555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CVV72_32565	COG1672	PFAM Archaeal ATPase
CVV72_32565	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CVV72_32570	COG2188	Transcriptional regulator
CVV72_32585	COG0640	Transcriptional regulator
CVV72_32605	COG1595	DNA-templated transcription, initiation
CVV72_32620	COG0583	DNA-binding transcription factor activity
CVV72_32630	COG3795	YCII-related domain
CVV72_32635	COG4941	Belongs to the sigma-70 factor family
CVV72_32655	COG1620	l-lactate permease
CVV72_32665	COG1832	CoA-binding protein
CVV72_32675	COG3971	2-oxopent-4-enoate hydratase activity
CVV72_32715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CVV72_32725	COG0346	lactoylglutathione lyase activity
CVV72_32730	COG0400	carboxylic ester hydrolase activity
CVV72_32740	COG5416	Lipopolysaccharide assembly protein A domain
CVV72_32770	COG1752	Esterase of the alpha-beta hydrolase superfamily
CVV72_32775	COG0456	acetyltransferase
CVV72_32785	COG1917	Cupin 2, conserved barrel domain protein
CVV72_32790	COG5285	phytanoyl-CoA dioxygenase
CVV72_32795	COG3629	intracellular signal transduction
CVV72_32795	COG3903	Transcriptional regulator
CVV72_32835	COG2971	BadF BadG BcrA BcrD
CVV72_32840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CVV72_32845	COG2188	Transcriptional regulator
CVV72_32850	COG0477	Major facilitator Superfamily
CVV72_32865	COG0352	thiamine-phosphate diphosphorylase activity
CVV72_32870	COG2022	thiamine diphosphate biosynthetic process
CVV72_32870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVV72_32880	COG2022	thiamine diphosphate biosynthetic process
CVV72_32905	COG1733	regulation of RNA biosynthetic process
CVV72_32915	COG0351	phosphomethylpyrimidine kinase
CVV72_32920	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CVV72_32925	COG1280	lysine exporter protein (LysE YggA)
CVV72_32935	COG0242	peptide deformylase activity
CVV72_32950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVV72_32960	COG0688	phosphatidylethanolamine metabolic process
CVV72_32970	COG2261	transglycosylase associated protein
CVV72_33000	COG1278	Cold shock
CVV72_33010	COG0459	protein refolding
CVV72_33035	COG4948	Mandelate Racemase Muconate Lactonizing
CVV72_33040	COG3629	intracellular signal transduction
CVV72_33040	COG3903	Transcriptional regulator
CVV72_33055	COG1061	Type III restriction enzyme res subunit
CVV72_33085	COG1116	anion transmembrane transporter activity
CVV72_33085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CVV72_33090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CVV72_33095	COG1174	glycine betaine transport
CVV72_33115	COG2018	Roadblock/LC7 domain
CVV72_33130	COG2018	Roadblock/LC7 domain
CVV72_33165	COG0521	Mo-molybdopterin cofactor biosynthetic process
CVV72_33175	COG1388	LysM domain
CVV72_33190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CVV72_33195	COG1846	Transcriptional regulator
CVV72_33230	COG3304	Inner membrane component domain
CVV72_33235	COG0384	phenazine biosynthesis protein PhzF
CVV72_33255	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_33265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVV72_33285	COG1278	Cold shock
CVV72_33295	COG2814	Major facilitator Superfamily
CVV72_33320	COG2252	PERMEase
CVV72_33330	COG2814	Major facilitator Superfamily
CVV72_33375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVV72_33425	COG2205	protein histidine kinase activity
CVV72_33430	COG0745	RESPONSE REGULATOR receiver
CVV72_33445	COG0577	efflux transmembrane transporter activity
CVV72_33445	COG1136	(ABC) transporter
CVV72_33450	COG0577	efflux transmembrane transporter activity
CVV72_33450	COG1136	(ABC) transporter
CVV72_33455	COG5650	phosphatidylinositol metabolic process
CVV72_33475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CVV72_33480	COG2197	response regulator
CVV72_33495	COG1131	(ABC) transporter
CVV72_33530	COG0831	urea catabolic process
CVV72_33535	COG0832	Belongs to the urease beta subunit family
CVV72_33540	COG0804	urea catabolic process
CVV72_33550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CVV72_33555	COG0829	nickel cation binding
CVV72_33590	COG0642	Histidine kinase
CVV72_33595	COG1116	anion transmembrane transporter activity
CVV72_33600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CVV72_33615	COG0259	pyridoxamine-phosphate oxidase activity
CVV72_33645	COG1309	transcriptional regulator
CVV72_33655	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_33660	COG2017	converts alpha-aldose to the beta-anomer
CVV72_33670	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CVV72_33680	COG1960	acyl-CoA dehydrogenase activity
CVV72_33700	COG0415	Belongs to the DNA photolyase family
CVV72_33705	COG1668	transmembrane transport
CVV72_33710	COG4152	abc transporter atp-binding protein
CVV72_33745	COG0277	FAD linked oxidase domain protein
CVV72_33800	COG1169	isochorismate synthase
CVV72_33810	COG1301	dicarboxylic acid transport
CVV72_33830	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_33835	COG1024	Enoyl-CoA hydratase
CVV72_33840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CVV72_33850	COG1321	iron dependent repressor
CVV72_33870	COG1984	allophanate hydrolase subunit 2
CVV72_33875	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CVV72_33880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CVV72_33885	COG4336	lyase activity
CVV72_33890	COG2814	Major facilitator Superfamily
CVV72_33905	COG1940	carbohydrate kinase activity
CVV72_33960	COG0583	DNA-binding transcription factor activity
CVV72_33965	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CVV72_33970	COG0702	epimerase
CVV72_33985	COG4941	Belongs to the sigma-70 factor family
CVV72_34000	COG4221	oxidoreductase activity
CVV72_34035	COG3629	intracellular signal transduction
CVV72_34035	COG3903	Transcriptional regulator
CVV72_34060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CVV72_34075	COG0210	DNA helicase
CVV72_34125	COG0210	DNA helicase
CVV72_34135	COG1401	restriction endodeoxyribonuclease activity
CVV72_34140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CVV72_34160	COG2197	response regulator
CVV72_34165	COG2860	membrane
CVV72_34175	COG2205	protein histidine kinase activity
CVV72_34180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CVV72_34190	COG1349	DNA-binding transcription factor activity
CVV72_34195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CVV72_34230	COG0745	RESPONSE REGULATOR receiver
CVV72_34235	COG5002	protein histidine kinase activity
CVV72_34255	COG0521	Mo-molybdopterin cofactor biosynthetic process
CVV72_34255	COG0315	cyclic pyranopterin monophosphate synthase activity
CVV72_34295	COG2197	response regulator
CVV72_34340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CVV72_34345	COG1960	acyl-CoA dehydrogenase activity
CVV72_34390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVV72_34400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CVV72_34410	COG2226	methyltransferase
CVV72_34445	COG2318	DinB family
CVV72_34455	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_34470	COG2258	MOSC domain
CVV72_34555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVV72_34560	COG0084	hydrolase, TatD family'
CVV72_34585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CVV72_34590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CVV72_34595	COG0488	(ABC) transporter
CVV72_34600	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_34615	COG0193	aminoacyl-tRNA hydrolase activity
CVV72_34645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CVV72_34690	COG2133	pyrroloquinoline quinone binding
CVV72_34720	COG1595	DNA-templated transcription, initiation
CVV72_34730	COG1131	(ABC) transporter
CVV72_34755	COG0492	ferredoxin-NADP+ reductase activity
CVV72_34760	COG1396	sequence-specific DNA binding
CVV72_34775	COG0148	phosphopyruvate hydratase activity
CVV72_34800	COG4166	transmembrane transport
CVV72_34805	COG0601	transmembrane transport
CVV72_34810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVV72_34815	COG0444	Belongs to the ABC transporter superfamily
CVV72_34820	COG4608	Belongs to the ABC transporter superfamily
CVV72_34825	COG1404	Belongs to the peptidase S8 family
CVV72_34835	COG1515	deoxyribonuclease V activity
CVV72_34845	COG1252	NADH dehydrogenase
CVV72_34865	COG0745	RESPONSE REGULATOR receiver
CVV72_34875	COG2197	response regulator
CVV72_34880	COG4585	Histidine kinase
CVV72_34905	COG0406	alpha-ribazole phosphatase activity
CVV72_34910	COG2124	cytochrome p450
CVV72_34925	COG1472	Belongs to the glycosyl hydrolase 3 family
CVV72_34950	COG1902	pentaerythritol trinitrate reductase activity
CVV72_34990	COG2391	methyltransferase activity
CVV72_34995	COG0477	Major facilitator Superfamily
CVV72_35000	COG0183	Belongs to the thiolase family
CVV72_35060	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CVV72_35070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVV72_35075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVV72_35085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CVV72_35095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CVV72_35105	COG1331	Highly conserved protein containing a thioredoxin domain
CVV72_35150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CVV72_35165	COG1733	regulation of RNA biosynthetic process
CVV72_35200	COG1793	dna ligase
CVV72_35220	COG0114	fumarate hydratase activity
CVV72_35225	COG0492	ferredoxin-NADP+ reductase activity
CVV72_35240	COG1722	exodeoxyribonuclease VII activity
CVV72_35250	COG1570	exodeoxyribonuclease VII activity
CVV72_35260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CVV72_35275	COG0420	3'-5' exonuclease activity
CVV72_35280	COG0419	ATPase involved in DNA repair
CVV72_35295	COG0012	GTP binding
CVV72_35340	COG2234	aminopeptidase activity
CVV72_35355	COG2154	pterin-4-alpha-carbinolamine dehydratase
CVV72_35365	COG4149	molybdate abc transporter
CVV72_35370	COG3842	ATPase activity
CVV72_35380	COG1131	(ABC) transporter
CVV72_35405	COG0180	Tryptophanyl-tRNA synthetase
CVV72_35415	COG1217	gtp-binding protein TYPA
CVV72_35420	COG0747	negative chemotaxis
CVV72_35430	COG0601	transmembrane transport
CVV72_35445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CVV72_35460	COG1994	Peptidase M50
CVV72_35490	COG2835	tetraacyldisaccharide 4'-kinase activity
CVV72_35500	COG1482	cell wall glycoprotein biosynthetic process
CVV72_35510	COG3629	intracellular signal transduction
CVV72_35510	COG3903	Transcriptional regulator
CVV72_35520	COG0531	amino acid
CVV72_35535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CVV72_35560	COG4638	Rieske (2fe-2S)
CVV72_35565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVV72_35575	COG1414	Transcriptional regulator
CVV72_35580	COG2146	nitrite reductase [NAD(P)H] activity
CVV72_35585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CVV72_35590	COG0745	RESPONSE REGULATOR receiver
CVV72_35595	COG5002	protein histidine kinase activity
CVV72_35595	COG5000	phosphorelay sensor kinase activity
CVV72_35600	COG5401	PFAM Sporulation and spore germination
CVV72_35610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CVV72_35615	COG0653	protein targeting
CVV72_35625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVV72_35630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVV72_35645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVV72_35665	COG1162	GTPase activity
CVV72_35670	COG2135	peptidase activity
CVV72_35685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CVV72_35715	COG1597	lipid kinase activity
CVV72_35730	COG0406	alpha-ribazole phosphatase activity
CVV72_35750	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CVV72_35755	COG0281	malic enzyme
CVV72_35770	COG1125	glycine betaine transport
CVV72_35770	COG0517	IMP dehydrogenase activity
CVV72_35775	COG1174	glycine betaine transport
CVV72_35780	COG1174	glycine betaine transport
CVV72_35790	COG3153	acetyltransferase
CVV72_35810	COG0567	Dehydrogenase, E1 component
CVV72_35810	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVV72_35830	COG1132	(ABC) transporter
CVV72_35845	COG0686	Belongs to the AlaDH PNT family
CVV72_35865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CVV72_35865	COG2508	Transcriptional regulator
CVV72_35875	COG1695	Transcriptional regulator
CVV72_35880	COG0346	lactoylglutathione lyase activity
CVV72_35890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CVV72_35905	COG2755	lipolytic protein G-D-S-L family
CVV72_35910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CVV72_35920	COG1960	acyl-CoA dehydrogenase activity
CVV72_35935	COG4221	oxidoreductase activity
CVV72_35950	COG1960	acyl-CoA dehydrogenase activity
CVV72_35970	COG0183	Belongs to the thiolase family
CVV72_35975	COG1024	Enoyl-CoA hydratase
CVV72_35975	COG1250	3-hydroxyacyl-CoA dehydrogenase
CVV72_36005	COG0477	Major facilitator Superfamily
CVV72_36010	COG0028	Belongs to the TPP enzyme family
CVV72_36025	COG3629	intracellular signal transduction
CVV72_36025	COG3903	Transcriptional regulator
CVV72_36040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CVV72_36050	COG0473	3-isopropylmalate dehydrogenase activity
CVV72_36095	COG0667	Aldo Keto reductase
CVV72_36125	COG2133	pyrroloquinoline quinone binding
CVV72_36135	COG0435	Glutathione S-transferase
CVV72_36140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVV72_36175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CVV72_36215	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_36235	COG2910	NAD(P)H-binding
CVV72_36250	COG1846	Transcriptional regulator
CVV72_36265	COG4941	Belongs to the sigma-70 factor family
CVV72_36285	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CVV72_36300	COG1053	succinate dehydrogenase
CVV72_36310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CVV72_36315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVV72_36330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CVV72_36340	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_36355	COG4221	oxidoreductase activity
CVV72_36390	COG0022	dehydrogenase e1 component
CVV72_36395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CVV72_36410	COG2124	cytochrome p450
CVV72_36415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_36445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVV72_36455	COG0596	Alpha beta hydrolase
CVV72_36475	COG0018	arginyl-trna synthetase
CVV72_36480	COG0019	diaminopimelate decarboxylase activity
CVV72_36485	COG0460	homoserine dehydrogenase
CVV72_36490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CVV72_36495	COG0083	homoserine kinase activity
CVV72_36500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CVV72_36500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CVV72_36515	COG0254	rRNA binding
CVV72_36535	COG0596	Alpha beta hydrolase
CVV72_36540	COG0789	Transcriptional regulator
CVV72_36545	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CVV72_36550	COG2890	protein-(glutamine-N5) methyltransferase activity
CVV72_36565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CVV72_36575	COG0356	it plays a direct role in the translocation of protons across the membrane
CVV72_36580	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CVV72_36585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CVV72_36590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CVV72_36595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CVV72_36600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CVV72_36605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CVV72_36610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CVV72_36620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CVV72_36635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CVV72_36650	COG1280	lysine exporter protein (LysE YggA)
CVV72_36655	COG1280	lysine exporter protein (LysE YggA)
CVV72_36670	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CVV72_36670	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CVV72_36675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVV72_36680	COG0765	amino acid transport
CVV72_36685	COG0765	amino acid transport
CVV72_36690	COG1126	abc transporter atp-binding protein
CVV72_36700	COG4977	sequence-specific DNA binding
CVV72_36715	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CVV72_36720	COG1752	Esterase of the alpha-beta hydrolase superfamily
CVV72_36750	COG2376	Dihydroxyacetone kinase
CVV72_36785	COG1522	sequence-specific DNA binding
CVV72_36790	COG0626	cystathionine gamma-synthase activity
CVV72_36815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CVV72_36840	COG1819	glycosyl
CVV72_36850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CVV72_36885	COG1268	BioY protein
CVV72_36895	COG0800	Aldolase
CVV72_36900	COG1335	isochorismatase
CVV72_36905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CVV72_36920	COG3191	aminopeptidase activity
CVV72_36940	COG1794	racemase activity, acting on amino acids and derivatives
CVV72_36955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CVV72_36965	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CVV72_36970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CVV72_37005	COG0587	DNA-directed DNA polymerase activity
CVV72_37085	COG1316	TRANSCRIPTIONal
CVV72_37095	COG3706	GGDEF domain
CVV72_37110	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_37130	COG3844	kynureninase activity
CVV72_37145	COG2018	Roadblock/LC7 domain
CVV72_37160	COG2259	Doxx family
CVV72_37165	COG2259	Doxx family
CVV72_37175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVV72_37210	COG1408	metallophosphoesterase
CVV72_37215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CVV72_37255	COG3469	chitinase activity
CVV72_37265	COG0698	ribose 5-phosphate isomerase
CVV72_37285	COG2267	carboxylic ester hydrolase activity
CVV72_37290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CVV72_37300	COG2814	Major facilitator Superfamily
CVV72_37305	COG0789	Transcriptional regulator
CVV72_37310	COG0673	inositol 2-dehydrogenase activity
CVV72_37330	COG0492	ferredoxin-NADP+ reductase activity
CVV72_37335	COG1309	transcriptional regulator
CVV72_37340	COG1024	Enoyl-CoA hydratase
CVV72_37370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVV72_37405	COG1376	ErfK ybiS ycfS ynhG family protein
CVV72_37425	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CVV72_37430	COG0433	COG0433 Predicted ATPase
CVV72_37440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CVV72_37450	COG2226	methyltransferase
CVV72_37465	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CVV72_37470	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CVV72_37500	COG0346	lactoylglutathione lyase activity
CVV72_37505	COG0183	Belongs to the thiolase family
CVV72_37525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_37530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CVV72_37540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVV72_37550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVV72_37560	COG3279	Response regulator of the LytR AlgR family
CVV72_37565	COG3275	phosphorelay sensor kinase activity
CVV72_37595	COG1609	Transcriptional regulator
CVV72_37605	COG1231	oxidoreductase activity
CVV72_37610	COG3537	Alpha-1,2-mannosidase
CVV72_37620	COG1846	Transcriptional regulator
CVV72_37645	COG0058	SHG alpha-glucan phosphorylase activity
CVV72_37685	COG1119	ATPase activity
CVV72_37690	COG1024	Enoyl-CoA hydratase
CVV72_37695	COG2226	methyltransferase
CVV72_37790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CVV72_37820	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CVV72_37825	COG2272	Belongs to the type-B carboxylesterase lipase family
CVV72_37845	COG1595	DNA-templated transcription, initiation
CVV72_37850	COG1252	NADH dehydrogenase
CVV72_37865	COG3883	PFAM NLP P60 protein
CVV72_37865	COG0791	NLP P60 protein
CVV72_37870	COG1957	nucleoside hydrolase
CVV72_37875	COG0110	maltose O-acetyltransferase activity
CVV72_37895	COG0702	epimerase
CVV72_37910	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CVV72_37920	COG3250	beta-galactosidase activity
CVV72_37935	COG0386	Belongs to the glutathione peroxidase family
CVV72_37945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CVV72_37955	COG1307	EDD domain protein, DegV family
CVV72_37965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CVV72_37990	COG0477	Major facilitator Superfamily
CVV72_38000	COG0482	sulfurtransferase activity
CVV72_38010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVV72_38030	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CVV72_38045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CVV72_38050	COG0154	amidase activity
CVV72_38090	COG0129	dihydroxy-acid dehydratase activity
CVV72_38105	COG0440	acetolactate synthase activity
CVV72_38110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CVV72_38175	COG1404	Belongs to the peptidase S8 family
CVV72_38180	COG0473	3-isopropylmalate dehydrogenase activity
CVV72_38190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CVV72_38195	COG0179	Fumarylacetoacetate (FAA) hydrolase
CVV72_38225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CVV72_38240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVV72_38260	COG2072	flavoprotein involved in K transport
CVV72_38265	COG0492	ferredoxin-NADP+ reductase activity
CVV72_38300	COG0454	-acetyltransferase
CVV72_38300	COG0456	acetyltransferase
CVV72_38310	COG0583	DNA-binding transcription factor activity
CVV72_38325	COG0019	diaminopimelate decarboxylase activity
CVV72_38330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CVV72_38335	COG0534	Mate efflux family protein
CVV72_38350	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CVV72_38370	COG1366	Belongs to the anti-sigma-factor antagonist family
CVV72_38430	COG0714	Associated with various cellular activities
CVV72_38460	COG2205	protein histidine kinase activity
CVV72_38465	COG0745	RESPONSE REGULATOR receiver
CVV72_38475	COG0464	growth
CVV72_38480	COG0745	RESPONSE REGULATOR receiver
CVV72_38530	COG1674	ftsk spoiiie
CVV72_38565	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CVV72_38570	COG0066	3-isopropylmalate dehydratase activity
CVV72_38575	COG0776	regulation of translation
CVV72_38580	COG0494	nUDIX hydrolase
CVV72_38580	COG0406	alpha-ribazole phosphatase activity
CVV72_38590	COG1920	GTP binding
CVV72_38600	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CVV72_38615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CVV72_38640	COG0745	RESPONSE REGULATOR receiver
CVV72_38645	COG2205	protein histidine kinase activity
CVV72_38655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_38690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CVV72_38695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CVV72_38700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CVV72_38705	COG1461	Dihydroxyacetone kinase
CVV72_38750	COG1404	Belongs to the peptidase S8 family
CVV72_38755	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CVV72_38765	COG3835	regulator
CVV72_38815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CVV72_38840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CVV72_38850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVV72_38855	COG2319	Wd-40 repeat
CVV72_38855	COG4249	Peptidase C14 caspase catalytic subunit p20
CVV72_38860	COG3973	AAA domain
CVV72_38865	COG0742	ribosomal rna small subunit methyltransferase
CVV72_38870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CVV72_38900	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CVV72_38905	COG0571	ribonuclease III activity
CVV72_38910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CVV72_38945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_38960	COG0017	Asparaginyl-tRNA synthetase
CVV72_38970	COG0174	glutamine synthetase
CVV72_38975	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CVV72_38980	COG1012	belongs to the aldehyde dehydrogenase family
CVV72_38995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CVV72_38995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CVV72_39000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CVV72_39005	COG0509	glycine decarboxylation via glycine cleavage system
CVV72_39010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CVV72_39015	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CVV72_39020	COG1760	l-serine dehydratase
CVV72_39025	COG2186	Transcriptional regulator
CVV72_39030	COG0659	secondary active sulfate transmembrane transporter activity
CVV72_39040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVV72_39045	COG4122	O-methyltransferase activity
CVV72_39050	COG1120	ATPase activity
CVV72_39055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_39065	COG4221	oxidoreductase activity
CVV72_39080	COG2814	Major facilitator Superfamily
CVV72_39085	COG0179	Fumarylacetoacetate (FAA) hydrolase
CVV72_39090	COG4948	Mandelate Racemase Muconate Lactonizing
CVV72_39095	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_39105	COG1129	ABC transporter
CVV72_39110	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVV72_39115	COG2186	Transcriptional regulator
CVV72_39165	COG1929	Belongs to the glycerate kinase type-1 family
CVV72_39185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CVV72_39190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CVV72_39200	COG3485	protocatechuate 3,4-dioxygenase
CVV72_39205	COG3485	protocatechuate 3,4-dioxygenase
CVV72_39210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CVV72_39215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CVV72_39220	COG1414	Transcriptional regulator
CVV72_39225	COG0746	molybdenum cofactor guanylyltransferase activity
CVV72_39255	COG1522	sequence-specific DNA binding
CVV72_39285	COG0492	ferredoxin-NADP+ reductase activity
CVV72_39305	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_39315	COG0583	DNA-binding transcription factor activity
CVV72_39320	COG3962	Belongs to the TPP enzyme family
CVV72_39325	COG3718	enzyme involved in inositol metabolism
CVV72_39330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVV72_39350	COG1082	Xylose isomerase domain protein TIM barrel
CVV72_39355	COG1609	Transcriptional regulator
CVV72_39360	COG0673	inositol 2-dehydrogenase activity
CVV72_39375	COG1725	Transcriptional regulator
CVV72_39380	COG1131	(ABC) transporter
CVV72_39405	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CVV72_39410	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CVV72_39415	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CVV72_39435	COG1254	Belongs to the acylphosphatase family
CVV72_39450	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CVV72_39465	COG0477	Major facilitator Superfamily
CVV72_39475	COG1414	Transcriptional regulator
CVV72_39480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CVV72_39495	COG1309	transcriptional regulator
CVV72_39520	COG3835	regulator
CVV72_39540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CVV72_39545	COG0590	tRNA wobble adenosine to inosine editing
CVV72_39550	COG2252	PERMEase
CVV72_39565	COG1309	transcriptional regulator
CVV72_39585	COG2351	hydroxyisourate hydrolase activity
CVV72_39600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CVV72_39605	COG4266	Belongs to the allantoicase family
CVV72_39610	COG1832	CoA-binding protein
CVV72_39615	COG2873	o-acetylhomoserine
CVV72_39670	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CVV72_39680	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CVV72_39710	COG0228	four-way junction DNA binding
CVV72_39725	COG0336	Belongs to the RNA methyltransferase TrmD family
CVV72_39730	COG0335	large ribosomal subunit rRNA binding
CVV72_39735	COG0681	Belongs to the peptidase S26 family
CVV72_39740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CVV72_39750	COG0792	nuclease activity
CVV72_39770	COG1191	sigma factor activity
CVV72_39785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CVV72_39790	COG0528	UMP kinase activity
CVV72_39820	COG1695	Transcriptional regulator
CVV72_39830	COG0477	Major facilitator Superfamily
CVV72_39840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CVV72_39910	COG3540	Alkaline phosphatase
CVV72_39915	COG1028	Short-chain dehydrogenase reductase Sdr
CVV72_39915	COG0604	alcohol dehydrogenase
CVV72_39915	COG3321	synthase
CVV72_39945	COG2124	cytochrome p450
CVV72_39955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVV72_39965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CVV72_39980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CVV72_39985	COG0750	zinc metalloprotease
CVV72_39990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CVV72_39995	COG0454	-acetyltransferase
CVV72_39995	COG0456	acetyltransferase
CVV72_40010	COG2186	Transcriptional regulator
CVV72_40015	COG2807	transmembrane transport
CVV72_40045	COG0156	8-amino-7-oxononanoate synthase activity
CVV72_40050	COG0513	Belongs to the DEAD box helicase family
CVV72_40065	COG1404	Belongs to the peptidase S8 family
CVV72_40085	COG3022	response to hydroperoxide
CVV72_40110	COG0442	prolyl-tRNA aminoacylation
CVV72_40120	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CVV72_40155	COG1396	sequence-specific DNA binding
CVV72_40170	COG2197	response regulator
CVV72_40205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CVV72_40215	COG0095	Lipoate-protein ligase
CVV72_40250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CVV72_40265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CVV72_40280	COG0668	transmembrane transport
CVV72_40285	COG3201	nicotinamide mononucleotide transporter
CVV72_40295	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CVV72_40350	COG3226	Transcriptional regulator
CVV72_40370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CVV72_40390	COG1113	amino acid transport
CVV72_40410	COG0587	DNA-directed DNA polymerase activity
CVV72_40415	COG0477	Major facilitator Superfamily
CVV72_40445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CVV72_40450	COG1376	ErfK ybiS ycfS ynhG family protein
CVV72_40455	COG1752	Esterase of the alpha-beta hydrolase superfamily
CVV72_40460	COG0586	Pfam SNARE associated Golgi protein
CVV72_40465	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CVV72_40480	COG1309	transcriptional regulator
CVV72_40490	COG0321	lipoyl(octanoyl) transferase activity
CVV72_40500	COG1090	epimerase
CVV72_40515	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVV72_40520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVV72_40535	COG0596	Alpha beta hydrolase
CVV72_40540	COG0318	PFAM AMP-dependent synthetase and ligase
CVV72_40555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CVV72_40570	COG2867	negative regulation of translational initiation
CVV72_40570	COG2226	methyltransferase
CVV72_40580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVV72_40605	COG0477	Major facilitator Superfamily
CVV72_40610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVV72_40615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVV72_40650	COG1793	dna ligase
CVV72_40655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CVV72_40670	COG0475	glutathione-regulated potassium exporter activity
CVV72_40675	COG1819	glycosyl
CVV72_40680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CVV72_40700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CVV72_40710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CVV72_40720	COG2188	Transcriptional regulator
CVV72_40725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CVV72_40735	COG0667	Aldo Keto reductase
CVV72_40755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVV72_40770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CVV72_40890	COG1475	DNA binding
CVV72_40895	COG1192	Involved in chromosome partitioning