locus-tag	class	description
MUY22_00020	COG0596	Alpha beta hydrolase
MUY22_00025	COG4221	oxidoreductase activity
MUY22_00035	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MUY22_00090	COG1175	transmembrane transport
MUY22_00100	COG0366	Alpha amylase catalytic
MUY22_00130	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_00160	COG1609	Transcriptional regulator
MUY22_00175	COG1414	Transcriptional regulator
MUY22_00190	COG0531	amino acid
MUY22_00195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MUY22_00235	COG0183	Belongs to the thiolase family
MUY22_00245	COG1021	2,3-dihydroxybenzoate-AMP ligase
MUY22_00270	COG0277	FAD linked oxidase domain protein
MUY22_00275	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MUY22_00280	COG0583	DNA-binding transcription factor activity
MUY22_00325	COG1024	Enoyl-CoA hydratase
MUY22_00370	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_00380	COG1643	Atp-dependent helicase
MUY22_00410	COG3268	Saccharopine dehydrogenase
MUY22_00425	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_00430	COG2072	flavoprotein involved in K transport
MUY22_00450	COG1796	DNA polymerase
MUY22_00450	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MUY22_00460	COG1802	Transcriptional regulator
MUY22_00485	COG3706	GGDEF domain
MUY22_00500	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MUY22_00535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MUY22_00550	COG0702	epimerase
MUY22_00560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUY22_00565	COG2318	DinB family
MUY22_00570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUY22_00580	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MUY22_00580	COG0235	Class ii aldolase
MUY22_00600	COG1695	Transcriptional regulator
MUY22_00610	COG3959	Transketolase, thiamine diphosphate binding domain
MUY22_00620	COG0277	FAD linked oxidase domain protein
MUY22_00620	COG0247	lactate metabolic process
MUY22_00630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MUY22_00635	COG1522	sequence-specific DNA binding
MUY22_00650	COG3537	Alpha-1,2-mannosidase
MUY22_00655	COG1739	Uncharacterized protein family UPF0029
MUY22_00660	COG0067	glutamate synthase
MUY22_00660	COG0069	glutamate synthase activity
MUY22_00660	COG0070	glutamate synthase
MUY22_00685	COG1349	DNA-binding transcription factor activity
MUY22_00710	COG1492	cobalamin metabolic process
MUY22_00715	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MUY22_00725	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MUY22_00730	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MUY22_00750	COG1797	cobyrinic acid a,c-diamide synthase activity
MUY22_00785	COG0778	Nitroreductase
MUY22_00815	COG1131	(ABC) transporter
MUY22_00825	COG1476	TRANSCRIPTIONal
MUY22_00840	COG3469	chitinase activity
MUY22_00845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUY22_00845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUY22_00855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MUY22_00870	COG2226	methyltransferase
MUY22_00880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUY22_00890	COG0433	COG0433 Predicted ATPase
MUY22_00895	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MUY22_00910	COG0477	Major facilitator Superfamily
MUY22_00915	COG0596	Alpha beta hydrolase
MUY22_00920	COG1733	regulation of RNA biosynthetic process
MUY22_00925	COG1376	ErfK ybiS ycfS ynhG family protein
MUY22_00950	COG2813	Specifically methylates the guanine in position
MUY22_00970	COG2986	histidine ammonia-lyase
MUY22_01000	COG5012	cobalamin binding
MUY22_01005	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MUY22_01015	COG2986	histidine ammonia-lyase
MUY22_01025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_01040	COG0477	Major facilitator Superfamily
MUY22_01045	COG0475	glutathione-regulated potassium exporter activity
MUY22_01055	COG1301	dicarboxylic acid transport
MUY22_01100	COG1674	ftsk spoiiie
MUY22_01110	COG1902	pentaerythritol trinitrate reductase activity
MUY22_01120	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUY22_01125	COG0583	DNA-binding transcription factor activity
MUY22_01135	COG3953	SLT domain
MUY22_01135	COG5280	Phage tail tape measure protein TP901
MUY22_01145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUY22_01155	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MUY22_01170	COG0183	Belongs to the thiolase family
MUY22_01175	COG2340	Cysteine-rich secretory protein family
MUY22_01195	COG1113	amino acid transport
MUY22_01215	COG1278	Cold shock
MUY22_01220	COG1802	Transcriptional regulator
MUY22_01245	COG2197	response regulator
MUY22_01250	COG2197	response regulator
MUY22_01285	COG1404	Belongs to the peptidase S8 family
MUY22_01295	COG0464	growth
MUY22_01305	COG0493	'glutamate synthase
MUY22_01305	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MUY22_01395	COG2175	clavaminate synthase activity
MUY22_01405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUY22_01420	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MUY22_01425	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_01485	COG0604	alcohol dehydrogenase
MUY22_01485	COG3321	synthase
MUY22_01505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUY22_01520	COG2124	cytochrome p450
MUY22_01525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUY22_01555	COG2124	cytochrome p450
MUY22_01560	COG1073	alpha beta
MUY22_01565	COG2986	histidine ammonia-lyase
MUY22_01575	COG0109	protoheme IX farnesyltransferase activity
MUY22_01590	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
MUY22_01630	COG0514	ATP-dependent DNA helicase (RecQ)
MUY22_01665	COG3629	intracellular signal transduction
MUY22_01665	COG3903	Transcriptional regulator
MUY22_01700	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MUY22_01700	COG1672	PFAM Archaeal ATPase
MUY22_01710	COG4733	cellulase activity
MUY22_01710	COG5297	Belongs to the glycosyl hydrolase family 6
MUY22_01720	COG1136	(ABC) transporter
MUY22_01730	COG2255	four-way junction helicase activity
MUY22_01755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUY22_01755	COG0519	Catalyzes the synthesis of GMP from XMP
MUY22_01765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MUY22_01775	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MUY22_01795	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_01820	COG1376	ErfK ybiS ycfS ynhG family protein
MUY22_01830	COG1733	regulation of RNA biosynthetic process
MUY22_01850	COG3409	Peptidoglycan-binding domain 1 protein
MUY22_01890	COG1201	RNA secondary structure unwinding
MUY22_01905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MUY22_01940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUY22_01945	COG2124	cytochrome p450
MUY22_01960	COG0657	acetylesterase activity
MUY22_02050	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_02100	COG1366	Belongs to the anti-sigma-factor antagonist family
MUY22_02105	COG1366	Belongs to the anti-sigma-factor antagonist family
MUY22_02110	COG2172	sigma factor antagonist activity
MUY22_02120	COG0784	Response regulator, receiver
MUY22_02120	COG2198	Histidine kinase
MUY22_02120	COG5002	protein histidine kinase activity
MUY22_02150	COG0778	Nitroreductase
MUY22_02150	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MUY22_02155	COG2022	thiamine diphosphate biosynthetic process
MUY22_02165	COG0515	serine threonine protein kinase
MUY22_02215	COG3402	PFAM membrane-flanked domain
MUY22_02225	COG0667	Aldo Keto reductase
MUY22_02230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUY22_02310	COG1819	glycosyl
MUY22_02315	COG1819	glycosyl
MUY22_02330	COG2986	histidine ammonia-lyase
MUY22_02340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MUY22_02350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUY22_02375	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MUY22_02400	COG0395	ABC-type sugar transport system, permease component
MUY22_02405	COG1175	transmembrane transport
MUY22_02410	COG1609	Transcriptional regulator
MUY22_02420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MUY22_02440	COG0667	Aldo Keto reductase
MUY22_02460	COG1595	DNA-templated transcription, initiation
MUY22_02470	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_02475	COG0129	dihydroxy-acid dehydratase activity
MUY22_02480	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MUY22_02505	COG0596	Alpha beta hydrolase
MUY22_02510	COG3903	Transcriptional regulator
MUY22_02510	COG3629	intracellular signal transduction
MUY22_02560	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MUY22_02585	COG0789	Transcriptional regulator
MUY22_02590	COG2814	Major facilitator Superfamily
MUY22_02630	COG2226	methyltransferase
MUY22_02635	COG2508	Transcriptional regulator
MUY22_02645	COG3655	Transcriptional regulator
MUY22_02670	COG0500	methyltransferase
MUY22_02720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_02725	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MUY22_02790	COG3226	Transcriptional regulator
MUY22_02795	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_02810	COG2146	nitrite reductase [NAD(P)H] activity
MUY22_02815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUY22_02835	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUY22_02855	COG0456	acetyltransferase
MUY22_02860	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_02890	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_02895	COG3537	Alpha-1,2-mannosidase
MUY22_02900	COG0745	RESPONSE REGULATOR receiver
MUY22_02905	COG5002	protein histidine kinase activity
MUY22_02910	COG0395	ABC-type sugar transport system, permease component
MUY22_02915	COG1175	transmembrane transport
MUY22_02925	COG1609	Transcriptional regulator
MUY22_02930	COG1233	COG1233 Phytoene dehydrogenase and related
MUY22_02960	COG0515	serine threonine protein kinase
MUY22_02960	COG2815	serine threonine protein kinase
MUY22_02980	COG2837	iron assimilation
MUY22_03005	COG0784	Response regulator, receiver
MUY22_03010	COG4251	negative regulation of phosphorylation
MUY22_03015	COG0745	RESPONSE REGULATOR receiver
MUY22_03040	COG2144	transferase activity, transferring acyl groups
MUY22_03060	COG2072	flavoprotein involved in K transport
MUY22_03120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUY22_03130	COG1309	transcriptional regulator
MUY22_03155	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_03165	COG0596	Alpha beta hydrolase
MUY22_03175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_03195	COG0662	Cupin 2, conserved barrel domain protein
MUY22_03225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MUY22_03230	COG1609	Transcriptional regulator
MUY22_03235	COG2814	Major facilitator Superfamily
MUY22_03250	COG1349	DNA-binding transcription factor activity
MUY22_03260	COG3842	ATPase activity
MUY22_03265	COG0395	ABC-type sugar transport system, permease component
MUY22_03270	COG1175	transmembrane transport
MUY22_03290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MUY22_03340	COG0706	membrane insertase activity
MUY22_03350	COG1408	metallophosphoesterase
MUY22_03365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MUY22_03370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUY22_03390	COG2018	Roadblock/LC7 domain
MUY22_03415	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_03435	COG1316	TRANSCRIPTIONal
MUY22_03475	COG4977	sequence-specific DNA binding
MUY22_03480	COG0667	Aldo Keto reductase
MUY22_03485	COG2207	Transcriptional regulator
MUY22_03520	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MUY22_03525	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MUY22_03535	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MUY22_03550	COG1794	racemase activity, acting on amino acids and derivatives
MUY22_03580	COG3191	aminopeptidase activity
MUY22_03595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MUY22_03600	COG1335	isochorismatase
MUY22_03615	COG1268	BioY protein
MUY22_03640	COG3830	Belongs to the UPF0237 family
MUY22_03640	COG0560	Phosphoserine phosphatase
MUY22_03645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MUY22_03655	COG2267	carboxylic ester hydrolase activity
MUY22_03680	COG0626	cystathionine gamma-synthase activity
MUY22_03685	COG1522	sequence-specific DNA binding
MUY22_03730	COG2376	Dihydroxyacetone kinase
MUY22_03760	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MUY22_03780	COG1335	isochorismatase
MUY22_03785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MUY22_03785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MUY22_03800	COG1280	lysine exporter protein (LysE YggA)
MUY22_03805	COG1280	lysine exporter protein (LysE YggA)
MUY22_03810	COG1280	lysine exporter protein (LysE YggA)
MUY22_03820	COG0702	epimerase
MUY22_03830	COG1309	transcriptional regulator
MUY22_03835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUY22_03845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MUY22_03860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MUY22_03865	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MUY22_03870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MUY22_03880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUY22_03885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MUY22_03890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUY22_03895	COG0356	it plays a direct role in the translocation of protons across the membrane
MUY22_03905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUY22_03920	COG2890	protein-(glutamine-N5) methyltransferase activity
MUY22_03930	COG0596	Alpha beta hydrolase
MUY22_03935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_03940	COG0463	Glycosyl transferase, family 2
MUY22_03960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MUY22_03965	COG0254	rRNA binding
MUY22_03975	COG0083	homoserine kinase activity
MUY22_03980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUY22_03985	COG0460	homoserine dehydrogenase
MUY22_03990	COG0019	diaminopimelate decarboxylase activity
MUY22_03995	COG0018	arginyl-trna synthetase
MUY22_04015	COG0596	Alpha beta hydrolase
MUY22_04050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_04085	COG3795	YCII-related domain
MUY22_04100	COG2910	NAD(P)H-binding
MUY22_04140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MUY22_04145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_04160	COG0483	inositol monophosphate 1-phosphatase activity
MUY22_04215	COG3345	alpha-galactosidase
MUY22_04225	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_04255	COG0667	Aldo Keto reductase
MUY22_04285	COG0154	amidase activity
MUY22_04315	COG0473	3-isopropylmalate dehydrogenase activity
MUY22_04325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MUY22_04335	COG0667	Aldo Keto reductase
MUY22_04345	COG0028	Belongs to the TPP enzyme family
MUY22_04360	COG0477	Major facilitator Superfamily
MUY22_04370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_04375	COG4585	Histidine kinase
MUY22_04380	COG2197	response regulator
MUY22_04385	COG2409	Drug exporters of the RND superfamily
MUY22_04395	COG3537	Alpha-1,2-mannosidase
MUY22_04400	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUY22_04400	COG1024	Enoyl-CoA hydratase
MUY22_04405	COG0183	Belongs to the thiolase family
MUY22_04410	COG1309	transcriptional regulator
MUY22_04465	COG1960	acyl-CoA dehydrogenase activity
MUY22_04470	COG1960	acyl-CoA dehydrogenase activity
MUY22_04490	COG4221	oxidoreductase activity
MUY22_04495	COG0454	-acetyltransferase
MUY22_04500	COG1960	acyl-CoA dehydrogenase activity
MUY22_04510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_04515	COG2755	lipolytic protein G-D-S-L family
MUY22_04550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MUY22_04565	COG2226	methyltransferase
MUY22_04570	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MUY22_04570	COG2508	Transcriptional regulator
MUY22_04585	COG0686	Belongs to the AlaDH PNT family
MUY22_04600	COG1132	(ABC) transporter
MUY22_04610	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUY22_04610	COG0567	Dehydrogenase, E1 component
MUY22_04645	COG1280	lysine exporter protein (LysE YggA)
MUY22_04660	COG1174	glycine betaine transport
MUY22_04665	COG1174	glycine betaine transport
MUY22_04670	COG1125	glycine betaine transport
MUY22_04670	COG0517	IMP dehydrogenase activity
MUY22_04685	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MUY22_04695	COG1846	Transcriptional regulator
MUY22_04710	COG0406	alpha-ribazole phosphatase activity
MUY22_04725	COG1597	lipid kinase activity
MUY22_04740	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MUY22_04750	COG1595	DNA-templated transcription, initiation
MUY22_04755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MUY22_04770	COG2135	peptidase activity
MUY22_04775	COG1162	GTPase activity
MUY22_04805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUY22_04810	COG1011	Hydrolase
MUY22_04820	COG2124	cytochrome p450
MUY22_04825	COG0653	protein targeting
MUY22_04830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MUY22_04850	COG5002	protein histidine kinase activity
MUY22_04855	COG0745	RESPONSE REGULATOR receiver
MUY22_04865	COG1414	Transcriptional regulator
MUY22_04870	COG2378	regulation of single-species biofilm formation
MUY22_04885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUY22_04950	COG0531	amino acid
MUY22_04960	COG3629	intracellular signal transduction
MUY22_04960	COG3903	Transcriptional regulator
MUY22_04965	COG1482	cell wall glycoprotein biosynthetic process
MUY22_04975	COG2835	tetraacyldisaccharide 4'-kinase activity
MUY22_05020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUY22_05030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_05035	COG0601	transmembrane transport
MUY22_05045	COG0747	negative chemotaxis
MUY22_05050	COG1217	gtp-binding protein TYPA
MUY22_05065	COG0180	Tryptophanyl-tRNA synthetase
MUY22_05070	COG0406	alpha-ribazole phosphatase activity
MUY22_05070	COG0494	nUDIX hydrolase
MUY22_05075	COG2205	protein histidine kinase activity
MUY22_05080	COG0745	RESPONSE REGULATOR receiver
MUY22_05090	COG1131	(ABC) transporter
MUY22_05105	COG3842	ATPase activity
MUY22_05110	COG4149	molybdate abc transporter
MUY22_05125	COG1733	regulation of RNA biosynthetic process
MUY22_05155	COG0012	GTP binding
MUY22_05170	COG0419	ATPase involved in DNA repair
MUY22_05175	COG0420	3'-5' exonuclease activity
MUY22_05190	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MUY22_05200	COG1570	exodeoxyribonuclease VII activity
MUY22_05210	COG1722	exodeoxyribonuclease VII activity
MUY22_05225	COG0492	ferredoxin-NADP+ reductase activity
MUY22_05230	COG0114	fumarate hydratase activity
MUY22_05235	COG0667	Aldo Keto reductase
MUY22_05245	COG1793	dna ligase
MUY22_05265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_05280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MUY22_05370	COG1331	Highly conserved protein containing a thioredoxin domain
MUY22_05385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MUY22_05390	COG4585	Histidine kinase
MUY22_05400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUY22_05410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MUY22_05415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_05425	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MUY22_05460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUY22_05500	COG0183	Belongs to the thiolase family
MUY22_05505	COG0477	Major facilitator Superfamily
MUY22_05510	COG2391	methyltransferase activity
MUY22_05570	COG3629	intracellular signal transduction
MUY22_05570	COG3903	Transcriptional regulator
MUY22_05575	COG2723	6-phospho-beta-galactosidase activity
MUY22_05600	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_05605	COG0667	Aldo Keto reductase
MUY22_05615	COG0477	Major facilitator Superfamily
MUY22_05625	COG2226	methyltransferase
MUY22_05645	COG0631	protein serine/threonine phosphatase activity
MUY22_05660	COG2207	Transcriptional regulator
MUY22_05670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MUY22_05670	COG0515	serine threonine protein kinase
MUY22_05685	COG0714	Associated with various cellular activities
MUY22_05705	COG2205	protein histidine kinase activity
MUY22_05715	COG3903	Transcriptional regulator
MUY22_05715	COG3629	intracellular signal transduction
MUY22_05720	COG0745	RESPONSE REGULATOR receiver
MUY22_05750	COG0667	Aldo Keto reductase
MUY22_05760	COG3979	chitinase
MUY22_05765	COG1252	NADH dehydrogenase
MUY22_05775	COG1515	deoxyribonuclease V activity
MUY22_05805	COG4608	Belongs to the ABC transporter superfamily
MUY22_05810	COG0444	Belongs to the ABC transporter superfamily
MUY22_05815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_05820	COG0601	transmembrane transport
MUY22_05850	COG0148	phosphopyruvate hydratase activity
MUY22_05870	COG0672	)-iron permease
MUY22_05875	COG2822	iron ion transport
MUY22_05880	COG2837	iron assimilation
MUY22_05920	COG1131	(ABC) transporter
MUY22_05930	COG1595	DNA-templated transcription, initiation
MUY22_05935	COG3956	TIGRFAM MazG family protein
MUY22_05960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_05980	COG4585	Histidine kinase
MUY22_05985	COG2197	response regulator
MUY22_05995	COG2133	pyrroloquinoline quinone binding
MUY22_06040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MUY22_06055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MUY22_06070	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MUY22_06075	COG0193	aminoacyl-tRNA hydrolase activity
MUY22_06095	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_06100	COG0488	(ABC) transporter
MUY22_06110	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MUY22_06120	COG0477	Major facilitator Superfamily
MUY22_06125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUY22_06140	COG0084	hydrolase, TatD family'
MUY22_06145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUY22_06160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUY22_06200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MUY22_06210	COG0515	serine threonine protein kinase
MUY22_06210	COG2815	serine threonine protein kinase
MUY22_06230	COG2258	MOSC domain
MUY22_06245	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_06265	COG4585	Histidine kinase
MUY22_06270	COG2197	response regulator
MUY22_06310	COG1716	ATPase activity
MUY22_06310	COG5001	Diguanylate cyclase
MUY22_06320	COG2124	cytochrome p450
MUY22_06330	COG1192	Involved in chromosome partitioning
MUY22_06410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUY22_06420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MUY22_06425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MUY22_06450	COG0521	Mo-molybdopterin cofactor biosynthetic process
MUY22_06450	COG0315	cyclic pyranopterin monophosphate synthase activity
MUY22_06465	COG5002	protein histidine kinase activity
MUY22_06470	COG0745	RESPONSE REGULATOR receiver
MUY22_06505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUY22_06515	COG1349	DNA-binding transcription factor activity
MUY22_06530	COG0745	RESPONSE REGULATOR receiver
MUY22_06535	COG2860	membrane
MUY22_06540	COG2197	response regulator
MUY22_06625	COG0443	Heat shock 70 kDa protein
MUY22_06645	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_06670	COG0402	S-adenosylhomocysteine deaminase activity
MUY22_06685	COG2197	response regulator
MUY22_06710	COG0477	Major facilitator Superfamily
MUY22_06715	COG0583	DNA-binding transcription factor activity
MUY22_06730	COG0438	transferase activity, transferring glycosyl groups
MUY22_06735	COG0515	serine threonine protein kinase
MUY22_06735	COG2815	serine threonine protein kinase
MUY22_06740	COG0483	inositol monophosphate 1-phosphatase activity
MUY22_06750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUY22_06765	COG0438	transferase activity, transferring glycosyl groups
MUY22_06785	COG1793	dna ligase
MUY22_06785	COG3285	dna ligase
MUY22_06800	COG0583	DNA-binding transcription factor activity
MUY22_06805	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MUY22_06805	COG2755	lipolytic protein G-D-S-L family
MUY22_06850	COG1960	acyl-CoA dehydrogenase activity
MUY22_06870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_06875	COG0601	transmembrane transport
MUY22_06885	COG0747	negative chemotaxis
MUY22_06925	COG3469	chitinase activity
MUY22_06935	COG2814	Major facilitator Superfamily
MUY22_06940	COG4336	lyase activity
MUY22_06945	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MUY22_06955	COG1984	allophanate hydrolase subunit 2
MUY22_06990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_07000	COG1321	iron dependent repressor
MUY22_07020	COG1024	Enoyl-CoA hydratase
MUY22_07025	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_07060	COG1169	isochorismate synthase
MUY22_07075	COG2182	Extracellular solute-binding protein
MUY22_07080	COG1175	transmembrane transport
MUY22_07085	COG0395	ABC-type sugar transport system, permease component
MUY22_07130	COG0277	FAD linked oxidase domain protein
MUY22_07155	COG4152	abc transporter atp-binding protein
MUY22_07160	COG1668	transmembrane transport
MUY22_07165	COG0415	Belongs to the DNA photolyase family
MUY22_07185	COG1960	acyl-CoA dehydrogenase activity
MUY22_07200	COG1228	amidohydrolase
MUY22_07210	COG2017	converts alpha-aldose to the beta-anomer
MUY22_07220	COG1309	transcriptional regulator
MUY22_07245	COG2814	Major facilitator Superfamily
MUY22_07250	COG0259	pyridoxamine-phosphate oxidase activity
MUY22_07265	COG0829	nickel cation binding
MUY22_07270	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MUY22_07280	COG0804	urea catabolic process
MUY22_07285	COG0832	Belongs to the urease beta subunit family
MUY22_07290	COG0831	urea catabolic process
MUY22_07310	COG1131	(ABC) transporter
MUY22_07325	COG2197	response regulator
MUY22_07330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MUY22_07345	COG5650	phosphatidylinositol metabolic process
MUY22_07350	COG1228	amidohydrolase
MUY22_07355	COG0577	efflux transmembrane transporter activity
MUY22_07355	COG1136	(ABC) transporter
MUY22_07360	COG0577	efflux transmembrane transporter activity
MUY22_07360	COG1136	(ABC) transporter
MUY22_07375	COG0745	RESPONSE REGULATOR receiver
MUY22_07380	COG2205	protein histidine kinase activity
MUY22_07400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUY22_07415	COG5398	heme oxygenase
MUY22_07435	COG2814	Major facilitator Superfamily
MUY22_07450	COG2252	PERMEase
MUY22_07480	COG2814	Major facilitator Superfamily
MUY22_07490	COG1278	Cold shock
MUY22_07510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUY22_07515	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_07525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUY22_07575	COG3304	Inner membrane component domain
MUY22_07580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MUY22_07615	COG1846	Transcriptional regulator
MUY22_07685	COG2018	Roadblock/LC7 domain
MUY22_07700	COG2018	Roadblock/LC7 domain
MUY22_07710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUY22_07715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUY22_07720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUY22_07725	COG1116	anion transmembrane transporter activity
MUY22_07735	COG2826	transposase and inactivated derivatives, IS30 family
MUY22_07785	COG2318	DinB family
MUY22_07800	COG3903	Transcriptional regulator
MUY22_07800	COG3629	intracellular signal transduction
MUY22_07805	COG4948	Mandelate Racemase Muconate Lactonizing
MUY22_07820	COG0459	protein refolding
MUY22_07830	COG1278	Cold shock
MUY22_07850	COG2211	Major facilitator Superfamily
MUY22_07860	COG2261	transglycosylase associated protein
MUY22_07870	COG0688	phosphatidylethanolamine metabolic process
MUY22_07880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUY22_07895	COG0242	peptide deformylase activity
MUY22_07910	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MUY22_07925	COG1733	regulation of RNA biosynthetic process
MUY22_07955	COG2022	thiamine diphosphate biosynthetic process
MUY22_07965	COG2022	thiamine diphosphate biosynthetic process
MUY22_07965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUY22_07970	COG0352	thiamine-phosphate diphosphorylase activity
MUY22_07985	COG0477	Major facilitator Superfamily
MUY22_07995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MUY22_08000	COG2971	BadF BadG BcrA BcrD
MUY22_08010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MUY22_08040	COG3629	intracellular signal transduction
MUY22_08040	COG3903	Transcriptional regulator
MUY22_08045	COG5285	phytanoyl-CoA dioxygenase
MUY22_08050	COG1917	Cupin 2, conserved barrel domain protein
MUY22_08060	COG0456	acetyltransferase
MUY22_08065	COG1752	Esterase of the alpha-beta hydrolase superfamily
MUY22_08075	COG4399	Belongs to the UPF0754 family
MUY22_08090	COG5416	Lipopolysaccharide assembly protein A domain
MUY22_08100	COG0400	carboxylic ester hydrolase activity
MUY22_08105	COG0346	lactoylglutathione lyase activity
MUY22_08175	COG1132	(ABC) transporter
MUY22_08200	COG0346	lactoylglutathione lyase activity
MUY22_08210	COG1832	CoA-binding protein
MUY22_08225	COG0745	RESPONSE REGULATOR receiver
MUY22_08230	COG2205	protein histidine kinase activity
MUY22_08235	COG1492	cobalamin metabolic process
MUY22_08240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUY22_08250	COG1620	l-lactate permease
MUY22_08265	COG4941	Belongs to the sigma-70 factor family
MUY22_08275	COG3795	YCII-related domain
MUY22_08330	COG1595	DNA-templated transcription, initiation
MUY22_08360	COG1846	Transcriptional regulator
MUY22_08365	COG0439	Biotin carboxylase
MUY22_08370	COG0511	ligase activity, forming carbon-carbon bonds
MUY22_08375	COG0825	malonyl-CoA metabolic process
MUY22_08375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MUY22_08415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUY22_08435	COG3104	oligopeptide transport
MUY22_08440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_08450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_08460	COG2345	Transcriptional regulator
MUY22_08470	COG2345	Transcriptional regulator
MUY22_08495	COG0662	Cupin 2, conserved barrel domain protein
MUY22_08500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUY22_08505	COG1309	transcriptional regulator
MUY22_08530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUY22_08535	COG2186	Transcriptional regulator
MUY22_08550	COG0477	Major facilitator Superfamily
MUY22_08560	COG0367	asparagine synthase
MUY22_08565	COG3629	intracellular signal transduction
MUY22_08565	COG3903	Transcriptional regulator
MUY22_08575	COG3903	Transcriptional regulator
MUY22_08575	COG3629	intracellular signal transduction
MUY22_08575	COG3903	Transcriptional regulator
MUY22_08575	COG3629	intracellular signal transduction
MUY22_08590	COG3942	CHAP domain
MUY22_08590	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUY22_08620	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MUY22_08650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MUY22_08655	COG2847	Copper chaperone PCu(A)C
MUY22_08660	COG1329	Transcriptional regulator
MUY22_08665	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MUY22_08670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MUY22_08690	COG0215	cysteine-tRNA ligase activity
MUY22_08755	COG4399	Belongs to the UPF0754 family
MUY22_08760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUY22_08765	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MUY22_08765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MUY22_08770	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUY22_08775	COG1609	Transcriptional regulator
MUY22_08790	COG1194	a g-specific adenine glycosylase
MUY22_08815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MUY22_08845	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MUY22_08855	COG1396	sequence-specific DNA binding
MUY22_08890	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MUY22_08905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MUY22_08910	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MUY22_08915	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MUY22_08940	COG0789	Transcriptional regulator
MUY22_08955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MUY22_08970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUY22_09000	COG0037	tRNA processing
MUY22_09010	COG2027	D-alanyl-D-alanine carboxypeptidase
MUY22_09015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MUY22_09030	COG0483	inositol monophosphate 1-phosphatase activity
MUY22_09035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MUY22_09040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MUY22_09070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MUY22_09085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MUY22_09090	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUY22_09115	COG1754	DNA topoisomerase type I activity
MUY22_09115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUY22_09135	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MUY22_09140	COG1205	dead DEAH box helicase
MUY22_09140	COG1111	helicase
MUY22_09190	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_09195	COG3876	Protein conserved in bacteria
MUY22_09200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MUY22_09205	COG1737	Transcriptional regulator
MUY22_09210	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MUY22_09215	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MUY22_09235	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MUY22_09245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUY22_09265	COG3104	oligopeptide transport
MUY22_09270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MUY22_09280	COG0596	Alpha beta hydrolase
MUY22_09330	COG0477	Major facilitator Superfamily
MUY22_09420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MUY22_09435	COG3209	COG3209 Rhs family protein
MUY22_09445	COG1408	metallophosphoesterase
MUY22_09495	COG0463	Glycosyl transferase, family 2
MUY22_09500	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MUY22_09510	COG2192	nodulation
MUY22_09525	COG1902	pentaerythritol trinitrate reductase activity
MUY22_09530	COG0076	glutamate decarboxylase activity
MUY22_09535	COG0783	Belongs to the Dps family
MUY22_09540	COG1764	response to oxidative stress
MUY22_09550	COG0657	acetylesterase activity
MUY22_09565	COG2814	Major facilitator Superfamily
MUY22_09580	COG1690	Belongs to the RtcB family
MUY22_09615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUY22_09625	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_09640	COG1309	transcriptional regulator
MUY22_09645	COG0583	DNA-binding transcription factor activity
MUY22_09650	COG0697	spore germination
MUY22_09665	COG4941	Belongs to the sigma-70 factor family
MUY22_09670	COG3795	YCII-related domain
MUY22_09680	COG4608	Belongs to the ABC transporter superfamily
MUY22_09690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_09695	COG0601	transmembrane transport
MUY22_09700	COG0747	negative chemotaxis
MUY22_09715	COG1216	Glycosyl transferase, family 2
MUY22_09730	COG1215	transferase activity, transferring glycosyl groups
MUY22_09740	COG3951	Flagellar rod assembly protein muramidase FlgJ
MUY22_09740	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUY22_09745	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MUY22_09750	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MUY22_09755	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUY22_09760	COG1733	regulation of RNA biosynthetic process
MUY22_09765	COG3467	pyridoxamine 5'-phosphate
MUY22_09810	COG1116	anion transmembrane transporter activity
MUY22_09815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUY22_09825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MUY22_09830	COG2205	protein histidine kinase activity
MUY22_09835	COG0745	RESPONSE REGULATOR receiver
MUY22_09850	COG2197	response regulator
MUY22_09875	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUY22_09930	COG1674	ftsk spoiiie
MUY22_09975	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
MUY22_09980	COG2175	clavaminate synthase activity
MUY22_09995	COG0702	epimerase
MUY22_10035	COG1473	amidohydrolase
MUY22_10050	COG4702	Belongs to the UPF0303 family
MUY22_10055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MUY22_10060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MUY22_10065	COG0789	Transcriptional regulator
MUY22_10075	COG0395	ABC-type sugar transport system, permease component
MUY22_10095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUY22_10125	COG3973	AAA domain
MUY22_10195	COG2188	Transcriptional regulator
MUY22_10200	COG1397	ADP-ribosylglycohydrolase
MUY22_10205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_10225	COG0596	Alpha beta hydrolase
MUY22_10230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MUY22_10240	COG1316	TRANSCRIPTIONal
MUY22_10250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MUY22_10275	COG0745	RESPONSE REGULATOR receiver
MUY22_10310	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MUY22_10315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUY22_10375	COG3845	ABC transporter
MUY22_10410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MUY22_10470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUY22_10475	COG1132	(ABC) transporter
MUY22_10480	COG1132	(ABC) transporter
MUY22_10490	COG0047	phosphoribosylformylglycinamidine synthase activity
MUY22_10495	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUY22_10540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MUY22_10555	COG1126	abc transporter atp-binding protein
MUY22_10560	COG0765	amino acid transport
MUY22_10570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUY22_10580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUY22_10590	COG4948	Mandelate Racemase Muconate Lactonizing
MUY22_10600	COG3345	alpha-galactosidase
MUY22_10605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_10625	COG0395	ABC-type sugar transport system, permease component
MUY22_10630	COG1175	transmembrane transport
MUY22_10665	COG1011	Hydrolase
MUY22_10675	COG0436	Aminotransferase
MUY22_10680	COG3953	SLT domain
MUY22_10680	COG5280	Phage tail tape measure protein TP901
MUY22_10715	COG0584	glycerophosphoryl diester phosphodiesterase
MUY22_10730	COG2814	Major facilitator Superfamily
MUY22_10735	COG0025	NhaP-type Na H and K H
MUY22_10740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_10750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MUY22_10765	COG0747	negative chemotaxis
MUY22_10775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_10805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_10855	COG0667	Aldo Keto reductase
MUY22_10860	COG0300	oxidoreductase activity
MUY22_10905	COG0586	Pfam SNARE associated Golgi protein
MUY22_10910	COG0277	FAD linked oxidase domain protein
MUY22_10915	COG3467	pyridoxamine 5'-phosphate
MUY22_10925	COG0477	Major facilitator Superfamily
MUY22_10935	COG0586	Pfam SNARE associated Golgi protein
MUY22_10945	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_10950	COG0572	uridine kinase
MUY22_10955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_10980	COG1609	Transcriptional regulator
MUY22_10985	COG0456	acetyltransferase
MUY22_11005	COG0243	molybdopterin cofactor binding
MUY22_11010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUY22_11040	COG1302	Protein conserved in bacteria
MUY22_11080	COG1136	(ABC) transporter
MUY22_11085	COG4221	oxidoreductase activity
MUY22_11100	COG1401	restriction endodeoxyribonuclease activity
MUY22_11125	COG0542	response to heat
MUY22_11145	COG1017	nitric oxide dioxygenase activity
MUY22_11145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUY22_11165	COG2826	transposase and inactivated derivatives, IS30 family
MUY22_11170	COG0789	Transcriptional regulator
MUY22_11175	COG0484	heat shock protein binding
MUY22_11180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MUY22_11185	COG0443	Heat shock 70 kDa protein
MUY22_11215	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MUY22_11220	COG3226	Transcriptional regulator
MUY22_11225	COG2076	Multidrug Resistance protein
MUY22_11230	COG2181	nitrate reductase activity
MUY22_11230	COG0247	lactate metabolic process
MUY22_11250	COG2340	Cysteine-rich secretory protein family
MUY22_11260	COG1846	Transcriptional regulator
MUY22_11270	COG0717	Belongs to the dCTP deaminase family
MUY22_11330	COG0546	phosphoglycolate phosphatase activity
MUY22_11355	COG0270	DNA (cytosine-5-)-methyltransferase activity
MUY22_11360	COG4941	Belongs to the sigma-70 factor family
MUY22_11365	COG3795	YCII-related domain
MUY22_11380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUY22_11390	COG0737	Belongs to the 5'-nucleotidase family
MUY22_11420	COG3663	DNA glycosylase
MUY22_11425	COG2197	response regulator
MUY22_11430	COG1960	acyl-CoA dehydrogenase activity
MUY22_11445	COG0477	Major facilitator Superfamily
MUY22_11470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MUY22_11495	COG1126	abc transporter atp-binding protein
MUY22_11505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUY22_11520	COG1305	Transglutaminase-like
MUY22_11525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUY22_11535	COG0022	dehydrogenase e1 component
MUY22_11540	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUY22_11570	COG3030	protein affecting phage T7 exclusion by the F plasmid
MUY22_11615	COG1309	transcriptional regulator
MUY22_11620	COG2030	dehydratase
MUY22_11625	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_11630	COG0183	Belongs to the thiolase family
MUY22_11660	COG0456	acetyltransferase
MUY22_11705	COG1131	(ABC) transporter
MUY22_11720	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MUY22_11735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MUY22_11760	COG4585	Histidine kinase
MUY22_11765	COG2197	response regulator
MUY22_11775	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_11795	COG1131	(ABC) transporter
MUY22_11810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MUY22_11820	COG1136	(ABC) transporter
MUY22_11830	COG2197	response regulator
MUY22_11835	COG0402	S-adenosylhomocysteine deaminase activity
MUY22_11840	COG4221	oxidoreductase activity
MUY22_11855	COG2814	Major facilitator Superfamily
MUY22_11860	COG1846	Transcriptional regulator
MUY22_11865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUY22_11875	COG1595	DNA-templated transcription, initiation
MUY22_11885	COG1695	Transcriptional regulator
MUY22_11895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUY22_11900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUY22_11905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUY22_11910	COG0673	inositol 2-dehydrogenase activity
MUY22_11945	COG0360	Binds together with S18 to 16S ribosomal RNA
MUY22_11955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MUY22_11960	COG0359	binds to the 23S rRNA
MUY22_12000	COG3384	dioxygenase
MUY22_12025	COG2197	response regulator
MUY22_12040	COG0477	Major facilitator Superfamily
MUY22_12045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUY22_12055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_12105	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_12110	COG0495	leucyl-tRNA aminoacylation
MUY22_12180	COG4585	Histidine kinase
MUY22_12185	COG0617	tRNA 3'-terminal CCA addition
MUY22_12215	COG1595	DNA-templated transcription, initiation
MUY22_12230	COG3118	belongs to the thioredoxin family
MUY22_12230	COG0492	ferredoxin-NADP+ reductase activity
MUY22_12235	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUY22_12235	COG3409	Peptidoglycan-binding domain 1 protein
MUY22_12250	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUY22_12260	COG1192	Involved in chromosome partitioning
MUY22_12265	COG0357	Ribosomal RNA small subunit methyltransferase G
MUY22_12275	COG0706	membrane insertase activity
MUY22_12300	COG0592	DNA-directed DNA polymerase activity
MUY22_12305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MUY22_12310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MUY22_12315	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MUY22_12320	COG0187	DNA topoisomerase II activity
MUY22_12400	COG2259	Doxx family
MUY22_12425	COG0457	Tetratricopeptide repeat
MUY22_12425	COG0705	Rhomboid family
MUY22_12440	COG3764	Sortase (surface protein transpeptidase)
MUY22_12515	COG2815	serine threonine protein kinase
MUY22_12515	COG0515	serine threonine protein kinase
MUY22_12520	COG0515	serine threonine protein kinase
MUY22_12525	COG0768	penicillin binding
MUY22_12540	COG1716	ATPase activity
MUY22_12545	COG1716	ATPase activity
MUY22_12585	COG0626	cystathionine gamma-synthase activity
MUY22_12610	COG0747	negative chemotaxis
MUY22_12620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_12625	COG0444	Belongs to the ABC transporter superfamily
MUY22_12630	COG4608	Belongs to the ABC transporter superfamily
MUY22_12635	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_12640	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_12665	COG2301	Belongs to the HpcH HpaI aldolase family
MUY22_12675	COG0702	epimerase
MUY22_12680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MUY22_12695	COG1309	transcriptional regulator
MUY22_12705	COG2211	Major facilitator Superfamily
MUY22_12735	COG1276	copper resistance
MUY22_12735	COG2372	response to copper ion
MUY22_12750	COG1174	glycine betaine transport
MUY22_12760	COG1174	glycine betaine transport
MUY22_12800	COG2226	methyltransferase
MUY22_12810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MUY22_12820	COG0405	Gamma-glutamyltransferase
MUY22_12835	COG0477	Major facilitator Superfamily
MUY22_12845	COG4585	Histidine kinase
MUY22_12850	COG2197	response regulator
MUY22_12875	COG1216	Glycosyl transferase, family 2
MUY22_12875	COG0438	transferase activity, transferring glycosyl groups
MUY22_12890	COG0515	serine threonine protein kinase
MUY22_12915	COG3397	chitin binding
MUY22_12935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUY22_12940	COG3275	phosphorelay sensor kinase activity
MUY22_12960	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_12965	COG1309	transcriptional regulator
MUY22_12975	COG3279	Response regulator of the LytR AlgR family
MUY22_12985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUY22_12995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUY22_13015	COG2814	Major facilitator Superfamily
MUY22_13020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUY22_13040	COG1191	sigma factor activity
MUY22_13145	COG1271	oxidase subunit
MUY22_13150	COG1294	oxidase, subunit
MUY22_13155	COG4988	ABC transporter
MUY22_13215	COG4715	Zinc finger, swim domain protein
MUY22_13230	COG1072	(Pantothenic acid kinase))
MUY22_13235	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MUY22_13245	COG0406	alpha-ribazole phosphatase activity
MUY22_13275	COG0754	glutathionylspermidine amidase activity
MUY22_13285	COG0596	Alpha beta hydrolase
MUY22_13290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUY22_13295	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MUY22_13305	COG0579	oxidoreductase
MUY22_13325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MUY22_13335	COG0438	transferase activity, transferring glycosyl groups
MUY22_13340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MUY22_13375	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MUY22_13390	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_13430	COG0561	phosphatase activity
MUY22_13435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_13455	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MUY22_13485	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_13490	COG0277	FAD linked oxidase domain protein
MUY22_13500	COG1216	Glycosyl transferase, family 2
MUY22_13555	COG1216	Glycosyl transferase, family 2
MUY22_13585	COG2089	acid synthase
MUY22_13590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MUY22_13595	COG1086	Polysaccharide biosynthesis protein
MUY22_13600	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
MUY22_13610	COG0596	Alpha beta hydrolase
MUY22_13625	COG1063	alcohol dehydrogenase
MUY22_13630	COG2234	aminopeptidase activity
MUY22_13685	COG4565	transcriptional regulatory protein
MUY22_13690	COG3290	protein histidine kinase activity
MUY22_13695	COG1116	anion transmembrane transporter activity
MUY22_13720	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MUY22_13720	COG1672	PFAM Archaeal ATPase
MUY22_13740	COG1522	sequence-specific DNA binding
MUY22_13745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUY22_13760	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MUY22_13765	COG2186	Transcriptional regulator
MUY22_13785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUY22_13795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUY22_13820	COG3469	chitinase activity
MUY22_13830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MUY22_13855	COG3584	3D domain protein
MUY22_13855	COG3583	domain protein
MUY22_13865	COG0667	Aldo Keto reductase
MUY22_13920	COG2801	Transposase and inactivated derivatives
MUY22_13920	COG3415	Transposase
MUY22_13925	COG3559	Exporter of polyketide antibiotics
MUY22_13930	COG1131	(ABC) transporter
MUY22_13975	COG0287	Prephenate dehydrogenase
MUY22_13980	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUY22_13980	COG1902	pentaerythritol trinitrate reductase activity
MUY22_14005	COG1846	Transcriptional regulator
MUY22_14030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUY22_14040	COG2318	DinB family
MUY22_14050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MUY22_14080	COG0515	serine threonine protein kinase
MUY22_14090	COG1132	(ABC) transporter
MUY22_14095	COG1132	(ABC) transporter
MUY22_14110	COG0028	Belongs to the TPP enzyme family
MUY22_14125	COG2217	Heavy metal translocating P-type atpase
MUY22_14130	COG3199	ATP-NAD kinase
MUY22_14135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUY22_14140	COG0022	dehydrogenase e1 component
MUY22_14160	COG2197	response regulator
MUY22_14170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUY22_14175	COG0515	serine threonine protein kinase
MUY22_14185	COG0477	Major facilitator Superfamily
MUY22_14195	COG1595	DNA-templated transcription, initiation
MUY22_14210	COG1278	Cold shock
MUY22_14350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MUY22_14390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MUY22_14425	COG2233	PERMEase
MUY22_14430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MUY22_14440	COG1414	Transcriptional regulator
MUY22_14455	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MUY22_14485	COG2826	transposase and inactivated derivatives, IS30 family
MUY22_14550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MUY22_14575	COG2364	Membrane
MUY22_14580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_14595	COG2733	membrane
MUY22_14615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MUY22_14620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MUY22_14650	COG2986	histidine ammonia-lyase
MUY22_14670	COG1174	glycine betaine transport
MUY22_14685	COG1846	Transcriptional regulator
MUY22_14690	COG0702	epimerase
MUY22_14710	COG2130	NADP-dependent
MUY22_14730	COG1064	alcohol dehydrogenase
MUY22_14760	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MUY22_14775	COG0438	transferase activity, transferring glycosyl groups
MUY22_14790	COG0588	phosphoglycerate mutase activity
MUY22_14800	COG0667	Aldo Keto reductase
MUY22_14805	COG5002	protein histidine kinase activity
MUY22_14835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MUY22_14870	COG1595	DNA-templated transcription, initiation
MUY22_14875	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_14890	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MUY22_14895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MUY22_14900	COG0181	hydroxymethylbilane synthase activity
MUY22_14905	COG1648	precorrin-2 dehydrogenase activity
MUY22_14905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUY22_14910	COG0113	porphobilinogen synthase activity
MUY22_14930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUY22_14935	COG1136	(ABC) transporter
MUY22_14935	COG0577	efflux transmembrane transporter activity
MUY22_14940	COG1136	(ABC) transporter
MUY22_14940	COG0577	efflux transmembrane transporter activity
MUY22_14950	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MUY22_14955	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUY22_14960	COG0406	alpha-ribazole phosphatase activity
MUY22_14980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_14985	COG0785	Cytochrome C biogenesis protein
MUY22_14995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MUY22_15015	COG1522	sequence-specific DNA binding
MUY22_15025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MUY22_15045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MUY22_15050	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MUY22_15085	COG0438	transferase activity, transferring glycosyl groups
MUY22_15095	COG2226	methyltransferase
MUY22_15110	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUY22_15115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUY22_15120	COG0649	NAD binding
MUY22_15135	COG1034	ATP synthesis coupled electron transport
MUY22_15140	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MUY22_15145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MUY22_15150	COG0839	Belongs to the complex I subunit 6 family
MUY22_15155	COG0713	ATP synthesis coupled electron transport
MUY22_15160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUY22_15170	COG1007	ATP synthesis coupled electron transport
MUY22_15205	COG0477	Major facilitator Superfamily
MUY22_15215	COG0142	geranyltranstransferase activity
MUY22_15230	COG1013	pyruvate-flavodoxin oxidoreductase activity
MUY22_15235	COG0674	pyruvate-flavodoxin oxidoreductase activity
MUY22_15235	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MUY22_15250	COG1522	sequence-specific DNA binding
MUY22_15255	COG1834	amidinotransferase
MUY22_15275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MUY22_15340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUY22_15345	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MUY22_15355	COG1215	transferase activity, transferring glycosyl groups
MUY22_15365	COG4310	Domain of unknown function (DUF2172)
MUY22_15375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUY22_15380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MUY22_15410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_15420	COG0501	Belongs to the peptidase M48B family
MUY22_15430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_15450	COG0454	-acetyltransferase
MUY22_15450	COG0456	acetyltransferase
MUY22_15470	COG1666	GTP binding
MUY22_15485	COG0395	ABC-type sugar transport system, permease component
MUY22_15490	COG1175	transmembrane transport
MUY22_15500	COG0366	Alpha amylase catalytic
MUY22_15505	COG1609	Transcriptional regulator
MUY22_15510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MUY22_15545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUY22_15550	COG2030	dehydratase
MUY22_15560	COG2755	lipolytic protein G-D-S-L family
MUY22_15570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_15605	COG0081	regulation of translation
MUY22_15625	COG0222	ribosome binding
MUY22_15640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MUY22_15665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MUY22_15695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MUY22_15700	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MUY22_15765	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MUY22_15770	COG0049	tRNA binding
MUY22_15775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MUY22_15785	COG0051	transcription antitermination factor activity, RNA binding
MUY22_15790	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MUY22_15795	COG0088	Forms part of the polypeptide exit tunnel
MUY22_15800	COG0089	rRNA binding
MUY22_15805	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MUY22_15810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MUY22_15815	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MUY22_15820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MUY22_15825	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MUY22_15830	COG0255	Belongs to the universal ribosomal protein uL29 family
MUY22_15835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MUY22_15840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MUY22_15845	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MUY22_15850	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MUY22_15860	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MUY22_15865	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MUY22_15870	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MUY22_15875	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MUY22_15880	COG1841	ribosomal large subunit assembly
MUY22_15900	COG1280	lysine exporter protein (LysE YggA)
MUY22_15910	COG0563	adenylate kinase activity
MUY22_15920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MUY22_15925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUY22_15940	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MUY22_15945	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MUY22_15950	COG0202	RNA polymerase activity
MUY22_15960	COG0101	tRNA pseudouridine synthase activity
MUY22_15990	COG1404	Belongs to the peptidase S8 family
MUY22_16000	COG1674	ftsk spoiiie
MUY22_16005	COG0443	Heat shock 70 kDa protein
MUY22_16045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MUY22_16050	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MUY22_16055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUY22_16065	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_16110	COG1070	Carbohydrate kinase
MUY22_16115	COG3842	ATPase activity
MUY22_16120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUY22_16130	COG0802	atpase or kinase
MUY22_16135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MUY22_16135	COG0825	malonyl-CoA metabolic process
MUY22_16140	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_16150	COG0456	acetyltransferase
MUY22_16155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MUY22_16160	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MUY22_16180	COG1215	transferase activity, transferring glycosyl groups
MUY22_16190	COG0640	Transcriptional regulator
MUY22_16200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MUY22_16205	COG0459	protein refolding
MUY22_16265	COG0516	GMP reductase activity
MUY22_16285	COG0277	FAD linked oxidase domain protein
MUY22_16290	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_16315	COG0519	Catalyzes the synthesis of GMP from XMP
MUY22_16315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUY22_16345	COG0583	DNA-binding transcription factor activity
MUY22_16350	COG0515	serine threonine protein kinase
MUY22_16350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MUY22_16355	COG0515	serine threonine protein kinase
MUY22_16405	COG0045	succinate-CoA ligase (ADP-forming) activity
MUY22_16430	COG0138	bifunctional purine biosynthesis protein purh
MUY22_16465	COG0587	DNA-directed DNA polymerase activity
MUY22_16500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MUY22_16510	COG2814	Major facilitator Superfamily
MUY22_16515	COG0640	Transcriptional regulator
MUY22_16520	COG2814	Major facilitator Superfamily
MUY22_16595	COG1846	Transcriptional regulator
MUY22_16610	COG0180	Tryptophanyl-tRNA synthetase
MUY22_16620	COG1295	ribonuclease BN
MUY22_16630	COG2130	NADP-dependent
MUY22_16640	COG1686	Belongs to the peptidase S11 family
MUY22_16660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MUY22_16675	COG2009	succinate dehydrogenase
MUY22_16680	COG1744	ABC transporter substrate-binding protein PnrA-like
MUY22_16685	COG3845	ABC transporter
MUY22_16695	COG1079	Belongs to the binding-protein-dependent transport system permease family
MUY22_16715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MUY22_16720	COG2271	Major facilitator Superfamily
MUY22_16745	COG1733	regulation of RNA biosynthetic process
MUY22_16755	COG2390	Transcriptional regulator
MUY22_16760	COG1063	alcohol dehydrogenase
MUY22_16775	COG0395	ABC-type sugar transport system, permease component
MUY22_16815	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_16820	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_16825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MUY22_16865	COG0789	Transcriptional regulator
MUY22_16870	COG0667	Aldo Keto reductase
MUY22_16885	COG0492	ferredoxin-NADP+ reductase activity
MUY22_16900	COG0475	glutathione-regulated potassium exporter activity
MUY22_16905	COG0745	RESPONSE REGULATOR receiver
MUY22_16910	COG2205	protein histidine kinase activity
MUY22_16930	COG1228	amidohydrolase
MUY22_16950	COG0655	NAD(P)H dehydrogenase (quinone) activity
MUY22_16955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUY22_16990	COG0515	serine threonine protein kinase
MUY22_17015	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUY22_17015	COG1473	amidohydrolase
MUY22_17055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MUY22_17060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUY22_17065	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUY22_17085	COG2197	response regulator
MUY22_17105	COG4770	biotin carboxylase activity
MUY22_17120	COG1301	dicarboxylic acid transport
MUY22_17125	COG0424	maF-like protein
MUY22_17155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_17160	COG1846	Transcriptional regulator
MUY22_17175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_17190	COG2197	response regulator
MUY22_17195	COG4585	Histidine kinase
MUY22_17210	COG0655	NAD(P)H dehydrogenase (quinone) activity
MUY22_17215	COG1309	transcriptional regulator
MUY22_17225	COG1733	regulation of RNA biosynthetic process
MUY22_17235	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_17260	COG1902	pentaerythritol trinitrate reductase activity
MUY22_17275	COG3103	Sh3 type 3 domain protein
MUY22_17275	COG0791	NLP P60 protein
MUY22_17275	COG1388	LysM domain
MUY22_17305	COG3537	Alpha-1,2-mannosidase
MUY22_17310	COG0483	inositol monophosphate 1-phosphatase activity
MUY22_17320	COG2205	protein histidine kinase activity
MUY22_17330	COG2197	response regulator
MUY22_17385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MUY22_17390	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_17400	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_17415	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MUY22_17440	COG2259	Doxx family
MUY22_17455	COG1316	TRANSCRIPTIONal
MUY22_17460	COG1316	TRANSCRIPTIONal
MUY22_17490	COG0438	transferase activity, transferring glycosyl groups
MUY22_17525	COG1725	Transcriptional regulator
MUY22_17540	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MUY22_17540	COG0778	Nitroreductase
MUY22_17545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MUY22_17635	COG5297	Belongs to the glycosyl hydrolase family 6
MUY22_17635	COG3250	beta-galactosidase activity
MUY22_17640	COG1611	Belongs to the LOG family
MUY22_17650	COG0583	DNA-binding transcription factor activity
MUY22_17670	COG4988	ABC transporter
MUY22_17675	COG1294	oxidase, subunit
MUY22_17680	COG1271	oxidase subunit
MUY22_17705	COG2818	Glycosylase
MUY22_17710	COG1024	Enoyl-CoA hydratase
MUY22_17720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUY22_17725	COG0583	DNA-binding transcription factor activity
MUY22_17730	COG2814	Major facilitator Superfamily
MUY22_17735	COG4122	O-methyltransferase activity
MUY22_17740	COG1595	DNA-templated transcription, initiation
MUY22_17750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUY22_17755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MUY22_17770	COG2239	Acts as a magnesium transporter
MUY22_17780	COG0330	HflC and HflK could
MUY22_17835	COG1309	transcriptional regulator
MUY22_17855	COG5001	Diguanylate cyclase
MUY22_17875	COG0598	Magnesium transport protein CorA
MUY22_17905	COG0613	PHP domain protein
MUY22_17910	COG2095	MarC family integral membrane protein
MUY22_17935	COG0513	Belongs to the DEAD box helicase family
MUY22_17980	COG2267	carboxylic ester hydrolase activity
MUY22_17985	COG1309	transcriptional regulator
MUY22_18010	COG0243	molybdopterin cofactor binding
MUY22_18015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUY22_18020	COG2223	nitrite transmembrane transporter activity
MUY22_18025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUY22_18025	COG2146	nitrite reductase [NAD(P)H] activity
MUY22_18030	COG2146	nitrite reductase [NAD(P)H] activity
MUY22_18030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUY22_18050	COG2378	regulation of single-species biofilm formation
MUY22_18075	COG0640	Transcriptional regulator
MUY22_18145	COG0714	Associated with various cellular activities
MUY22_18170	COG2321	neutral zinc metallopeptidase
MUY22_18190	COG0612	Peptidase, M16
MUY22_18210	COG1175	transmembrane transport
MUY22_18215	COG0395	ABC-type sugar transport system, permease component
MUY22_18220	COG1486	melibiose metabolic process
MUY22_18235	COG0640	Transcriptional regulator
MUY22_18250	COG3265	gluconokinase activity
MUY22_18260	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MUY22_18285	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MUY22_18305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MUY22_18400	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_18430	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_18435	COG3842	ATPase activity
MUY22_18440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MUY22_18445	COG1176	ABC-type spermidine putrescine transport system, permease component I
MUY22_18450	COG1177	transmembrane transport
MUY22_18465	COG1968	undecaprenyl-diphosphatase activity
MUY22_18475	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MUY22_18480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MUY22_18480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MUY22_18490	COG2318	DinB family
MUY22_18505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MUY22_18505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MUY22_18520	COG0653	protein targeting
MUY22_18545	COG0174	glutamine synthetase
MUY22_18550	COG0154	amidase activity
MUY22_18570	COG1522	sequence-specific DNA binding
MUY22_18580	COG0519	Catalyzes the synthesis of GMP from XMP
MUY22_18580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUY22_18590	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MUY22_18600	COG0174	glutamine synthetase
MUY22_18650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MUY22_18670	COG3480	Lon protease (S16) C-terminal proteolytic domain
MUY22_18680	COG1615	UPF0182 protein
MUY22_18710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MUY22_18715	COG2884	Cell division ATP-binding protein ftsE
MUY22_18720	COG2177	Part of the ABC transporter FtsEX involved in
MUY22_18725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MUY22_18745	COG2197	response regulator
MUY22_18750	COG4585	Histidine kinase
MUY22_18780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUY22_18790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MUY22_18835	COG2856	Zn peptidase
MUY22_18865	COG3706	GGDEF domain
MUY22_18880	COG2986	histidine ammonia-lyase
MUY22_18885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MUY22_18900	COG1228	amidohydrolase
MUY22_18905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_18915	COG3835	regulator
MUY22_18950	COG4585	Histidine kinase
MUY22_18955	COG2197	response regulator
MUY22_18985	COG1643	Atp-dependent helicase
MUY22_18990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUY22_19010	COG0791	NLP P60 protein
MUY22_19010	COG3883	PFAM NLP P60 protein
MUY22_19050	COG0183	Belongs to the thiolase family
MUY22_19060	COG2030	dehydratase
MUY22_19065	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_19070	COG1960	acyl-CoA dehydrogenase activity
MUY22_19075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUY22_19075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUY22_19080	COG0187	DNA topoisomerase II activity
MUY22_19110	COG0640	Transcriptional regulator
MUY22_19125	COG1309	transcriptional regulator
MUY22_19150	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_19155	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_19160	COG1129	ABC transporter
MUY22_19165	COG1879	ABC-type sugar transport system periplasmic component
MUY22_19170	COG1609	Transcriptional regulator
MUY22_19175	COG0419	ATPase involved in DNA repair
MUY22_19180	COG3345	alpha-galactosidase
MUY22_19190	COG0395	ABC-type sugar transport system, permease component
MUY22_19215	COG5640	endopeptidase activity
MUY22_19225	COG0300	oxidoreductase activity
MUY22_19245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MUY22_19265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MUY22_19280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MUY22_19320	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_19325	COG0017	Asparaginyl-tRNA synthetase
MUY22_19345	COG0596	Alpha beta hydrolase
MUY22_19355	COG0393	Putative heavy-metal-binding
MUY22_19360	COG0393	Putative heavy-metal-binding
MUY22_19370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_19380	COG1486	melibiose metabolic process
MUY22_19390	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_19395	COG1053	succinate dehydrogenase
MUY22_19400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_19405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MUY22_19420	COG0596	Alpha beta hydrolase
MUY22_19490	COG0697	spore germination
MUY22_19495	COG1846	Transcriptional regulator
MUY22_19500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_19515	COG3716	PTS system mannose fructose sorbose family IID component
MUY22_19550	COG4941	Belongs to the sigma-70 factor family
MUY22_19555	COG3795	YCII-related domain
MUY22_19565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUY22_19600	COG1309	transcriptional regulator
MUY22_19645	COG1136	(ABC) transporter
MUY22_19655	COG3629	intracellular signal transduction
MUY22_19655	COG3903	Transcriptional regulator
MUY22_19705	COG2197	response regulator
MUY22_19715	COG1131	(ABC) transporter
MUY22_19745	COG2205	protein histidine kinase activity
MUY22_19780	COG4941	Belongs to the sigma-70 factor family
MUY22_19795	COG1733	regulation of RNA biosynthetic process
MUY22_19830	COG2814	Major facilitator Superfamily
MUY22_19840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUY22_19915	COG3842	ATPase activity
MUY22_19930	COG1234	tRNA 3'-trailer cleavage
MUY22_19945	COG2272	Belongs to the type-B carboxylesterase lipase family
MUY22_19990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MUY22_19995	COG1017	nitric oxide dioxygenase activity
MUY22_19995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUY22_20055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUY22_20060	COG0765	amino acid transport
MUY22_20065	COG1126	abc transporter atp-binding protein
MUY22_20070	COG2964	Protein conserved in bacteria
MUY22_20095	COG1131	(ABC) transporter
MUY22_20125	COG2186	Transcriptional regulator
MUY22_20130	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_20135	COG1129	ABC transporter
MUY22_20155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUY22_20155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUY22_20160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUY22_20195	COG4991	sh3 domain protein
MUY22_20200	COG3629	intracellular signal transduction
MUY22_20200	COG3903	Transcriptional regulator
MUY22_20205	COG4991	sh3 domain protein
MUY22_20210	COG3540	Alkaline phosphatase
MUY22_20225	COG1940	carbohydrate kinase activity
MUY22_20245	COG4221	oxidoreductase activity
MUY22_20250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MUY22_20275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUY22_20295	COG0513	Belongs to the DEAD box helicase family
MUY22_20320	COG2207	Transcriptional regulator
MUY22_20330	COG2183	response to ionizing radiation
MUY22_20340	COG3903	Transcriptional regulator
MUY22_20340	COG3629	intracellular signal transduction
MUY22_20350	COG2072	flavoprotein involved in K transport
MUY22_20375	COG1309	transcriptional regulator
MUY22_20390	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_20390	COG2030	dehydratase
MUY22_20395	COG3396	Phenylacetate-CoA oxygenase
MUY22_20400	COG3460	Phenylacetate-CoA oxygenase
MUY22_20405	COG3396	Phenylacetate-CoA oxygenase
MUY22_20410	COG2151	metal-sulfur cluster biosynthetic enzyme
MUY22_20415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUY22_20420	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MUY22_20435	COG0604	alcohol dehydrogenase
MUY22_20450	COG0346	lactoylglutathione lyase activity
MUY22_20455	COG0183	Belongs to the thiolase family
MUY22_20475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_20480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MUY22_20490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUY22_20500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUY22_20510	COG3279	Response regulator of the LytR AlgR family
MUY22_20515	COG3275	phosphorelay sensor kinase activity
MUY22_20525	COG1879	ABC-type sugar transport system periplasmic component
MUY22_20530	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_20545	COG1609	Transcriptional regulator
MUY22_20550	COG3537	Alpha-1,2-mannosidase
MUY22_20555	COG3537	Alpha-1,2-mannosidase
MUY22_20565	COG1846	Transcriptional regulator
MUY22_20635	COG0740	serine-type endopeptidase activity
MUY22_20760	COG0058	SHG alpha-glucan phosphorylase activity
MUY22_20780	COG1119	ATPase activity
MUY22_20785	COG1024	Enoyl-CoA hydratase
MUY22_20790	COG2226	methyltransferase
MUY22_20815	COG3979	chitinase
MUY22_20825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_20860	COG0702	epimerase
MUY22_20865	COG1733	regulation of RNA biosynthetic process
MUY22_20885	COG1733	regulation of RNA biosynthetic process
MUY22_20900	COG1819	glycosyl
MUY22_20905	COG0791	NLP P60 protein
MUY22_20905	COG3883	PFAM NLP P60 protein
MUY22_20910	COG1957	nucleoside hydrolase
MUY22_20915	COG0110	maltose O-acetyltransferase activity
MUY22_20925	COG0531	amino acid
MUY22_20930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MUY22_20960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MUY22_20980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUY22_20990	COG3250	beta-galactosidase activity
MUY22_20995	COG1940	carbohydrate kinase activity
MUY22_20995	COG1846	Transcriptional regulator
MUY22_21010	COG0386	Belongs to the glutathione peroxidase family
MUY22_21020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUY22_21030	COG1307	EDD domain protein, DegV family
MUY22_21040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MUY22_21060	COG2197	response regulator
MUY22_21075	COG0482	sulfurtransferase activity
MUY22_21095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_21115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUY22_21130	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUY22_21135	COG0154	amidase activity
MUY22_21150	COG0673	inositol 2-dehydrogenase activity
MUY22_21165	COG0673	inositol 2-dehydrogenase activity
MUY22_21175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUY22_21185	COG0129	dihydroxy-acid dehydratase activity
MUY22_21200	COG0440	acetolactate synthase activity
MUY22_21205	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MUY22_21245	COG1404	Belongs to the peptidase S8 family
MUY22_21250	COG0473	3-isopropylmalate dehydrogenase activity
MUY22_21255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUY22_21260	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUY22_21270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUY22_21360	COG3507	Belongs to the glycosyl hydrolase 43 family
MUY22_21385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUY22_21405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MUY22_21415	COG0463	Glycosyl transferase, family 2
MUY22_21435	COG0297	glycogen (starch) synthase activity
MUY22_21455	COG0438	transferase activity, transferring glycosyl groups
MUY22_21510	COG1672	PFAM Archaeal ATPase
MUY22_21510	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MUY22_21555	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_21565	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_21600	COG4221	oxidoreductase activity
MUY22_21645	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_21655	COG4977	sequence-specific DNA binding
MUY22_21670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_21685	COG3629	intracellular signal transduction
MUY22_21685	COG3903	Transcriptional regulator
MUY22_21700	COG0776	regulation of translation
MUY22_21710	COG0420	3'-5' exonuclease activity
MUY22_21715	COG0419	ATPase involved in DNA repair
MUY22_21730	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_21755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MUY22_21760	COG0066	3-isopropylmalate dehydratase activity
MUY22_21770	COG3903	Transcriptional regulator
MUY22_21770	COG3629	intracellular signal transduction
MUY22_21785	COG1920	GTP binding
MUY22_21795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MUY22_21805	COG0252	asparaginase activity
MUY22_21810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUY22_21820	COG1477	protein flavinylation
MUY22_21835	COG0745	RESPONSE REGULATOR receiver
MUY22_21840	COG2205	protein histidine kinase activity
MUY22_21855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_21860	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUY22_21885	COG3345	alpha-galactosidase
MUY22_21890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MUY22_21895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MUY22_21905	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MUY22_21910	COG1461	Dihydroxyacetone kinase
MUY22_21935	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MUY22_21955	COG3835	regulator
MUY22_22000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MUY22_22025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MUY22_22035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_22040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_22055	COG2319	Wd-40 repeat
MUY22_22055	COG4249	Peptidase C14 caspase catalytic subunit p20
MUY22_22060	COG3973	AAA domain
MUY22_22065	COG0742	ribosomal rna small subunit methyltransferase
MUY22_22070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MUY22_22075	COG4290	ribonuclease
MUY22_22090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MUY22_22095	COG0571	ribonuclease III activity
MUY22_22100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUY22_22155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MUY22_22160	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_22180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUY22_22180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUY22_22185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MUY22_22190	COG0509	glycine decarboxylation via glycine cleavage system
MUY22_22195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MUY22_22200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MUY22_22205	COG1760	l-serine dehydratase
MUY22_22215	COG2186	Transcriptional regulator
MUY22_22220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUY22_22225	COG4122	O-methyltransferase activity
MUY22_22230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_22265	COG2814	Major facilitator Superfamily
MUY22_22270	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUY22_22275	COG4948	Mandelate Racemase Muconate Lactonizing
MUY22_22285	COG1879	ABC-type sugar transport system periplasmic component
MUY22_22290	COG1129	ABC transporter
MUY22_22295	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_22300	COG2186	Transcriptional regulator
MUY22_22315	COG3618	amidohydrolase
MUY22_22350	COG1929	Belongs to the glycerate kinase type-1 family
MUY22_22355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUY22_22375	COG1653	transport
MUY22_22385	COG0395	ABC-type sugar transport system, permease component
MUY22_22390	COG3345	alpha-galactosidase
MUY22_22395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MUY22_22405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MUY22_22410	COG0183	Belongs to the thiolase family
MUY22_22415	COG3485	protocatechuate 3,4-dioxygenase
MUY22_22420	COG3485	protocatechuate 3,4-dioxygenase
MUY22_22425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MUY22_22435	COG1414	Transcriptional regulator
MUY22_22445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MUY22_22495	COG3706	GGDEF domain
MUY22_22500	COG2072	flavoprotein involved in K transport
MUY22_22520	COG1309	transcriptional regulator
MUY22_22525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MUY22_22525	COG2124	cytochrome p450
MUY22_22530	COG3962	Belongs to the TPP enzyme family
MUY22_22535	COG3718	enzyme involved in inositol metabolism
MUY22_22545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_22565	COG1082	Xylose isomerase domain protein TIM barrel
MUY22_22570	COG1609	Transcriptional regulator
MUY22_22580	COG0673	inositol 2-dehydrogenase activity
MUY22_22605	COG0367	asparagine synthase
MUY22_22615	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MUY22_22620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MUY22_22625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MUY22_22645	COG1254	Belongs to the acylphosphatase family
MUY22_22660	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUY22_22665	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MUY22_22695	COG1414	Transcriptional regulator
MUY22_22700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MUY22_22720	COG3835	regulator
MUY22_22740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUY22_22745	COG3345	alpha-galactosidase
MUY22_22750	COG1309	transcriptional regulator
MUY22_22775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUY22_22780	COG4266	Belongs to the allantoicase family
MUY22_22795	COG1832	CoA-binding protein
MUY22_22800	COG2873	o-acetylhomoserine
MUY22_22855	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MUY22_22870	COG1309	transcriptional regulator
MUY22_22890	COG1309	transcriptional regulator
MUY22_22900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MUY22_22910	COG1132	(ABC) transporter
MUY22_22935	COG0228	four-way junction DNA binding
MUY22_22945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MUY22_22950	COG0336	Belongs to the RNA methyltransferase TrmD family
MUY22_22955	COG0335	large ribosomal subunit rRNA binding
MUY22_22960	COG0681	Belongs to the peptidase S26 family
MUY22_22965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUY22_22975	COG0792	nuclease activity
MUY22_22990	COG4974	Belongs to the 'phage' integrase family
MUY22_22995	COG1191	sigma factor activity
MUY22_23005	COG0052	Belongs to the universal ribosomal protein uS2 family
MUY22_23010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MUY22_23015	COG0528	UMP kinase activity
MUY22_23020	COG0233	cytoplasmic translational termination
MUY22_23050	COG1695	Transcriptional regulator
MUY22_23075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MUY22_23085	COG4552	Acetyltransferase involved in intracellular survival and related
MUY22_23100	COG1834	amidinotransferase
MUY22_23120	COG0789	Transcriptional regulator
MUY22_23130	COG3795	YCII-related domain
MUY22_23140	COG3795	YCII-related domain
MUY22_23145	COG4941	Belongs to the sigma-70 factor family
MUY22_23150	COG3547	Transposase (IS116 IS110 IS902 family)
MUY22_23170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUY22_23185	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_23200	COG0596	Alpha beta hydrolase
MUY22_23205	COG3629	intracellular signal transduction
MUY22_23205	COG3903	Transcriptional regulator
MUY22_23215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUY22_23220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_23225	COG2814	Major facilitator Superfamily
MUY22_23230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MUY22_23230	COG2755	lipolytic protein G-D-S-L family
MUY22_23245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MUY22_23255	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MUY22_23260	COG0750	zinc metalloprotease
MUY22_23265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MUY22_23290	COG0454	-acetyltransferase
MUY22_23290	COG0456	acetyltransferase
MUY22_23325	COG2186	Transcriptional regulator
MUY22_23370	COG0513	Belongs to the DEAD box helicase family
MUY22_23390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUY22_23395	COG3022	response to hydroperoxide
MUY22_23415	COG0442	prolyl-tRNA aminoacylation
MUY22_23430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MUY22_23495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MUY22_23500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MUY22_23510	COG0095	Lipoate-protein ligase
MUY22_23520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUY22_23550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUY22_23555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MUY22_23565	COG4152	abc transporter atp-binding protein
MUY22_23570	COG1668	transmembrane transport
MUY22_23575	COG0668	transmembrane transport
MUY22_23585	COG3201	nicotinamide mononucleotide transporter
MUY22_23590	COG1620	l-lactate permease
MUY22_23600	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_23610	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MUY22_23635	COG0477	Major facilitator Superfamily
MUY22_23670	COG1960	acyl-CoA dehydrogenase activity
MUY22_23680	COG1104	cysteine desulfurase activity
MUY22_23690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MUY22_23705	COG1113	amino acid transport
MUY22_23715	COG3537	Alpha-1,2-mannosidase
MUY22_23720	COG0587	DNA-directed DNA polymerase activity
MUY22_23725	COG0477	Major facilitator Superfamily
MUY22_23750	COG1376	ErfK ybiS ycfS ynhG family protein
MUY22_23775	COG0586	Pfam SNARE associated Golgi protein
MUY22_23780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MUY22_23785	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_23805	COG0321	lipoyl(octanoyl) transferase activity
MUY22_23820	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUY22_23825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUY22_23865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUY22_23880	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MUY22_23880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MUY22_23895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MUY22_23925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_23940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MUY22_23975	COG1845	cytochrome c oxidase, subunit III
MUY22_23980	COG2010	Cytochrome c
MUY22_23990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MUY22_24025	COG0438	transferase activity, transferring glycosyl groups
MUY22_24040	COG2124	cytochrome p450
MUY22_24045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MUY22_24050	COG0659	secondary active sulfate transmembrane transporter activity
MUY22_24055	COG0659	secondary active sulfate transmembrane transporter activity
MUY22_24060	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MUY22_24080	COG0501	Belongs to the peptidase M48B family
MUY22_24085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MUY22_24095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MUY22_24100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MUY22_24105	COG0157	Belongs to the NadC ModD family
MUY22_24110	COG1404	Belongs to the peptidase S8 family
MUY22_24145	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_24165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MUY22_24170	COG1674	ftsk spoiiie
MUY22_24195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MUY22_24215	COG2197	response regulator
MUY22_24220	COG2197	response regulator
MUY22_24230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUY22_24240	COG0131	Imidazoleglycerol-phosphate dehydratase
MUY22_24245	COG1234	tRNA 3'-trailer cleavage
MUY22_24255	COG2409	Drug exporters of the RND superfamily
MUY22_24260	COG1309	transcriptional regulator
MUY22_24265	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MUY22_24275	COG3959	Transketolase, thiamine diphosphate binding domain
MUY22_24280	COG3958	Transketolase
MUY22_24300	COG1960	acyl-CoA dehydrogenase activity
MUY22_24315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MUY22_24320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MUY22_24370	COG1309	transcriptional regulator
MUY22_24375	COG0107	imidazoleglycerol-phosphate synthase activity
MUY22_24385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MUY22_24420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUY22_24430	COG0134	indole-3-glycerol-phosphate synthase activity
MUY22_24435	COG0133	tryptophan synthase activity
MUY22_24440	COG0159	tryptophan synthase activity
MUY22_24460	COG0174	glutamine synthetase
MUY22_24470	COG1473	amidohydrolase
MUY22_24475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MUY22_24485	COG0069	glutamate synthase activity
MUY22_24485	COG0067	glutamate synthase
MUY22_24485	COG0070	glutamate synthase
MUY22_24495	COG1819	glycosyl
MUY22_24505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MUY22_24520	COG2268	Band 7 protein
MUY22_24530	COG0515	serine threonine protein kinase
MUY22_24530	COG2815	serine threonine protein kinase
MUY22_24565	COG0142	geranyltranstransferase activity
MUY22_24630	COG0242	peptide deformylase activity
MUY22_24635	COG1201	RNA secondary structure unwinding
MUY22_24640	COG1349	DNA-binding transcription factor activity
MUY22_24645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MUY22_24650	COG0443	Heat shock 70 kDa protein
MUY22_24660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MUY22_24665	COG2137	regulation of response to DNA damage stimulus
MUY22_24680	COG0800	Aldolase
MUY22_24700	COG1053	succinate dehydrogenase
MUY22_24715	COG1228	amidohydrolase
MUY22_24745	COG0765	amino acid transport
MUY22_24750	COG0765	amino acid transport
MUY22_24755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUY22_24760	COG1126	abc transporter atp-binding protein
MUY22_24765	COG0745	RESPONSE REGULATOR receiver
MUY22_24770	COG2205	protein histidine kinase activity
MUY22_24785	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_24790	COG1309	transcriptional regulator
MUY22_24825	COG0519	Catalyzes the synthesis of GMP from XMP
MUY22_24845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_24865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUY22_24875	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_24880	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MUY22_24960	COG0494	nUDIX hydrolase
MUY22_24980	COG4245	von Willebrand factor, type A
MUY22_25030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUY22_25040	COG1196	nuclear chromosome segregation
MUY22_25045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MUY22_25065	COG0525	valine-tRNA ligase activity
MUY22_25080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MUY22_25090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUY22_25100	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MUY22_25105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUY22_25130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MUY22_25140	COG1505	serine-type exopeptidase activity
MUY22_25165	COG0517	IMP dehydrogenase activity
MUY22_25165	COG0516	GMP reductase activity
MUY22_25175	COG2936	dipeptidyl-peptidase activity
MUY22_25180	COG2197	response regulator
MUY22_25185	COG4585	Histidine kinase
MUY22_25200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUY22_25205	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MUY22_25220	COG0123	including yeast histone deacetylase and acetoin utilization protein
MUY22_25235	COG1960	acyl-CoA dehydrogenase activity
MUY22_25240	COG1960	acyl-CoA dehydrogenase activity
MUY22_25250	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_25260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MUY22_25265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MUY22_25320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUY22_25355	COG3833	ABC-type maltose transport systems, permease component
MUY22_25385	COG0003	Pfam Anion-transporting ATPase
MUY22_25395	COG1940	carbohydrate kinase activity
MUY22_25410	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUY22_25435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MUY22_25445	COG2986	histidine ammonia-lyase
MUY22_25460	COG0640	Transcriptional regulator
MUY22_25480	COG1946	Acyl-CoA thioesterase
MUY22_25500	COG2197	response regulator
MUY22_25505	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_25520	COG1960	acyl-CoA dehydrogenase activity
MUY22_25525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_25565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUY22_25580	COG2018	Roadblock/LC7 domain
MUY22_25605	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MUY22_25605	COG1703	isobutyryl-CoA mutase activity
MUY22_25605	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MUY22_25615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_25620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_25630	COG1309	transcriptional regulator
MUY22_25635	COG1960	acyl-CoA dehydrogenase activity
MUY22_25640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MUY22_25650	COG0657	acetylesterase activity
MUY22_25660	COG0748	coenzyme F420 binding
MUY22_25670	COG1960	acyl-CoA dehydrogenase activity
MUY22_25675	COG1960	acyl-CoA dehydrogenase activity
MUY22_25700	COG0196	riboflavin kinase activity
MUY22_25705	COG2030	dehydratase
MUY22_25725	COG1053	succinate dehydrogenase
MUY22_25735	COG1960	acyl-CoA dehydrogenase activity
MUY22_25740	COG2267	carboxylic ester hydrolase activity
MUY22_25745	COG0346	lactoylglutathione lyase activity
MUY22_25750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUY22_25785	COG1960	acyl-CoA dehydrogenase activity
MUY22_25795	COG1960	acyl-CoA dehydrogenase activity
MUY22_25800	COG1024	Enoyl-CoA hydratase
MUY22_25805	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_25810	COG1960	acyl-CoA dehydrogenase activity
MUY22_25815	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_25820	COG1309	transcriptional regulator
MUY22_25825	COG0183	Belongs to the thiolase family
MUY22_25830	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUY22_25880	COG1473	amidohydrolase
MUY22_25890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUY22_25895	COG1228	amidohydrolase
MUY22_25900	COG0596	Alpha beta hydrolase
MUY22_25930	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_25940	COG0367	asparagine synthase
MUY22_25945	COG3321	synthase
MUY22_25945	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_25945	COG0604	alcohol dehydrogenase
MUY22_25955	COG0183	Belongs to the thiolase family
MUY22_25960	COG2124	cytochrome p450
MUY22_25975	COG1295	ribonuclease BN
MUY22_25980	COG3226	Transcriptional regulator
MUY22_26020	COG2070	2-Nitropropane dioxygenase
MUY22_26035	COG2188	Transcriptional regulator
MUY22_26045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUY22_26110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MUY22_26110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MUY22_26120	COG1490	D-aminoacyl-tRNA deacylase activity
MUY22_26145	COG2313	pseudouridylate synthase activity
MUY22_26170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUY22_26185	COG4213	ABC transporter substrate-binding protein
MUY22_26195	COG4214	carbohydrate transport
MUY22_26225	COG0531	amino acid
MUY22_26255	COG0366	Alpha amylase catalytic
MUY22_26270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MUY22_26290	COG1940	carbohydrate kinase activity
MUY22_26295	COG0483	inositol monophosphate 1-phosphatase activity
MUY22_26315	COG0756	dUTP diphosphatase activity
MUY22_26345	COG0569	domain protein
MUY22_26350	COG0531	amino acid
MUY22_26355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUY22_26365	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_26370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MUY22_26375	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_26380	COG0028	Belongs to the TPP enzyme family
MUY22_26400	COG0745	RESPONSE REGULATOR receiver
MUY22_26405	COG2205	protein histidine kinase activity
MUY22_26415	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUY22_26415	COG1024	Enoyl-CoA hydratase
MUY22_26420	COG0183	Belongs to the thiolase family
MUY22_26455	COG1309	transcriptional regulator
MUY22_26465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUY22_26470	COG2197	response regulator
MUY22_26480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MUY22_26490	COG3253	May function as heme-dependent peroxidase
MUY22_26495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_26515	COG3220	belongs to the UPF0276 family
MUY22_26530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUY22_26540	COG0515	serine threonine protein kinase
MUY22_26565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_26575	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MUY22_26575	COG2508	Transcriptional regulator
MUY22_26580	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_26585	COG0506	proline dehydrogenase activity
MUY22_26590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUY22_26605	COG1793	dna ligase
MUY22_26645	COG1595	DNA-templated transcription, initiation
MUY22_26675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUY22_26680	COG2326	polyphosphate kinase activity
MUY22_26735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MUY22_26755	COG2124	cytochrome p450
MUY22_26780	COG2084	Dehydrogenase
MUY22_26805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MUY22_26815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MUY22_26820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUY22_26825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MUY22_26830	COG1309	transcriptional regulator
MUY22_26855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUY22_26860	COG1263	PTS System
MUY22_26865	COG2188	Transcriptional regulator
MUY22_26870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUY22_26905	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MUY22_26910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MUY22_26915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MUY22_26920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MUY22_26925	COG0346	lactoylglutathione lyase activity
MUY22_26940	COG0006	proline dipeptidase activity
MUY22_26945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MUY22_26950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUY22_26960	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MUY22_26965	COG0540	Belongs to the ATCase OTCase family
MUY22_26980	COG0505	Belongs to the CarA family
MUY22_26985	COG0419	ATPase involved in DNA repair
MUY22_27000	COG0284	orotidine-5'-phosphate decarboxylase activity
MUY22_27010	COG0194	GDP metabolic process
MUY22_27015	COG1758	RNA polymerase activity
MUY22_27025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUY22_27030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MUY22_27060	COG0405	Gamma-glutamyltransferase
MUY22_27070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUY22_27090	COG1785	Belongs to the alkaline phosphatase family
MUY22_27095	COG2197	response regulator
MUY22_27100	COG4585	Histidine kinase
MUY22_27115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUY22_27115	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUY22_27120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MUY22_27140	COG0322	excinuclease ABC activity
MUY22_27145	COG1660	Displays ATPase and GTPase activities
MUY22_27150	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MUY22_27155	COG1481	regulation of sporulation
MUY22_27160	COG1215	transferase activity, transferring glycosyl groups
MUY22_27180	COG3250	beta-galactosidase activity
MUY22_27185	COG0408	coproporphyrinogen oxidase activity
MUY22_27220	COG1280	lysine exporter protein (LysE YggA)
MUY22_27230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MUY22_27235	COG0126	phosphoglycerate kinase activity
MUY22_27240	COG0149	triose-phosphate isomerase activity
MUY22_27270	COG0363	glucosamine-6-phosphate deaminase activity
MUY22_27290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MUY22_27300	COG0109	protoheme IX farnesyltransferase activity
MUY22_27395	COG0396	ATPase activity
MUY22_27410	COG2151	metal-sulfur cluster biosynthetic enzyme
MUY22_27420	COG1742	UPF0060 membrane protein
MUY22_27425	COG0681	Belongs to the peptidase S26 family
MUY22_27430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MUY22_27440	COG4585	Histidine kinase
MUY22_27460	COG0175	sulfate reduction
MUY22_27505	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MUY22_27520	COG0488	(ABC) transporter
MUY22_27545	COG1132	(ABC) transporter
MUY22_27550	COG4821	SIS domain
MUY22_27555	COG0596	Alpha beta hydrolase
MUY22_27560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MUY22_27565	COG1316	TRANSCRIPTIONal
MUY22_27570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUY22_27580	COG3706	GGDEF domain
MUY22_27580	COG2203	Gaf domain
MUY22_27580	COG5001	Diguanylate cyclase
MUY22_27580	COG4251	negative regulation of phosphorylation
MUY22_27590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MUY22_27600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUY22_27600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MUY22_27610	COG1024	Enoyl-CoA hydratase
MUY22_27625	COG1960	acyl-CoA dehydrogenase activity
MUY22_27630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_27670	COG3469	chitinase activity
MUY22_27680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MUY22_27705	COG1309	transcriptional regulator
MUY22_27710	COG2133	pyrroloquinoline quinone binding
MUY22_27730	COG1819	glycosyl
MUY22_27740	COG0789	Transcriptional regulator
MUY22_27745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MUY22_27780	COG0604	alcohol dehydrogenase
MUY22_27780	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_27780	COG3321	synthase
MUY22_27820	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_27830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_27840	COG3537	Alpha-1,2-mannosidase
MUY22_27870	COG1819	glycosyl
MUY22_27885	COG2197	response regulator
MUY22_27920	COG0604	alcohol dehydrogenase
MUY22_27920	COG3321	synthase
MUY22_27925	COG0604	alcohol dehydrogenase
MUY22_27925	COG3321	synthase
MUY22_27940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_27940	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_27940	COG3321	synthase
MUY22_27940	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_27940	COG0300	oxidoreductase activity
MUY22_27945	COG2124	cytochrome p450
MUY22_27970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_27985	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_27995	COG1309	transcriptional regulator
MUY22_28000	COG0596	Alpha beta hydrolase
MUY22_28005	COG1960	acyl-CoA dehydrogenase activity
MUY22_28010	COG1960	acyl-CoA dehydrogenase activity
MUY22_28045	COG4249	Peptidase C14 caspase catalytic subunit p20
MUY22_28045	COG2319	Wd-40 repeat
MUY22_28060	COG1819	glycosyl
MUY22_28065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_28080	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUY22_28100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUY22_28125	COG1509	lysine 2,3-aminomutase activity
MUY22_28160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MUY22_28180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MUY22_28190	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_28195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_28210	COG0604	alcohol dehydrogenase
MUY22_28210	COG3321	synthase
MUY22_28215	COG3321	synthase
MUY22_28215	COG0604	alcohol dehydrogenase
MUY22_28220	COG0604	alcohol dehydrogenase
MUY22_28220	COG3321	synthase
MUY22_28230	COG0604	alcohol dehydrogenase
MUY22_28230	COG3321	synthase
MUY22_28245	COG0604	alcohol dehydrogenase
MUY22_28250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUY22_28265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MUY22_28270	COG4279	zinc finger
MUY22_28320	COG4977	sequence-specific DNA binding
MUY22_28335	COG4166	transmembrane transport
MUY22_28350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUY22_28350	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUY22_28370	COG0277	FAD linked oxidase domain protein
MUY22_28415	COG2124	cytochrome p450
MUY22_28425	COG2124	cytochrome p450
MUY22_28455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_28475	COG1309	transcriptional regulator
MUY22_28585	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MUY22_28590	COG1414	Transcriptional regulator
MUY22_28595	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_28610	COG3384	dioxygenase
MUY22_28645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MUY22_28650	COG2186	Transcriptional regulator
MUY22_28655	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUY22_28670	COG1960	acyl-CoA dehydrogenase activity
MUY22_28680	COG1119	ATPase activity
MUY22_28685	COG0546	phosphoglycolate phosphatase activity
MUY22_28695	COG1063	alcohol dehydrogenase
MUY22_28705	COG2159	amidohydrolase
MUY22_28715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUY22_28720	COG1024	Enoyl-CoA hydratase
MUY22_28725	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_28730	COG2124	cytochrome p450
MUY22_28765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUY22_28800	COG1309	transcriptional regulator
MUY22_28815	COG1175	transmembrane transport
MUY22_28845	COG0395	ABC-type sugar transport system, permease component
MUY22_28875	COG0673	inositol 2-dehydrogenase activity
MUY22_28955	COG1454	alcohol dehydrogenase
MUY22_28960	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_29000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_29005	COG0583	DNA-binding transcription factor activity
MUY22_29065	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MUY22_29075	COG2357	RelA SpoT domain protein
MUY22_29090	COG1280	lysine exporter protein (LysE YggA)
MUY22_29095	COG0484	heat shock protein binding
MUY22_29145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MUY22_29150	COG0642	Histidine kinase
MUY22_29155	COG2018	Roadblock/LC7 domain
MUY22_29205	COG3629	intracellular signal transduction
MUY22_29215	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_29240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUY22_29260	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_29270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MUY22_29275	COG0765	amino acid transport
MUY22_29280	COG0765	amino acid transport
MUY22_29290	COG1126	abc transporter atp-binding protein
MUY22_29320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUY22_29340	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_29345	COG0473	3-isopropylmalate dehydrogenase activity
MUY22_29355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUY22_29385	COG1802	Transcriptional regulator
MUY22_29415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_29425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_29430	COG1309	transcriptional regulator
MUY22_29505	COG0444	Belongs to the ABC transporter superfamily
MUY22_29520	COG0747	negative chemotaxis
MUY22_29525	COG1609	Transcriptional regulator
MUY22_29530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUY22_29535	COG0704	Plays a role in the regulation of phosphate uptake
MUY22_29545	COG0306	phosphate transporter
MUY22_29610	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MUY22_29615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_29635	COG0017	Asparaginyl-tRNA synthetase
MUY22_29645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_29650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_29695	COG3629	intracellular signal transduction
MUY22_29695	COG3903	Transcriptional regulator
MUY22_29720	COG3250	beta-galactosidase activity
MUY22_29785	COG3629	intracellular signal transduction
MUY22_29785	COG3903	Transcriptional regulator
MUY22_29860	COG0247	lactate metabolic process
MUY22_29865	COG1139	Iron-sulfur cluster binding protein
MUY22_29870	COG1556	Lactate utilization protein
MUY22_29875	COG2197	response regulator
MUY22_29905	COG3250	beta-galactosidase activity
MUY22_29910	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_29920	COG0596	Alpha beta hydrolase
MUY22_29935	COG1609	Transcriptional regulator
MUY22_29975	COG1960	acyl-CoA dehydrogenase activity
MUY22_29980	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MUY22_29985	COG3250	beta-galactosidase activity
MUY22_30010	COG1335	isochorismatase
MUY22_30040	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_30050	COG0583	DNA-binding transcription factor activity
MUY22_30065	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MUY22_30095	COG1940	carbohydrate kinase activity
MUY22_30100	COG2814	Major facilitator Superfamily
MUY22_30130	COG0667	Aldo Keto reductase
MUY22_30150	COG3795	YCII-related domain
MUY22_30155	COG4941	Belongs to the sigma-70 factor family
MUY22_30160	COG0583	DNA-binding transcription factor activity
MUY22_30170	COG0745	RESPONSE REGULATOR receiver
MUY22_30190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MUY22_30195	COG1116	anion transmembrane transporter activity
MUY22_30205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUY22_30210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUY22_30235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_30260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_30265	COG0601	transmembrane transport
MUY22_30275	COG4172	Belongs to the ABC transporter superfamily
MUY22_30285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_30290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_30300	COG0477	Major facilitator Superfamily
MUY22_30320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUY22_30405	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_30420	COG0477	Major facilitator Superfamily
MUY22_30440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUY22_30445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUY22_30450	COG0587	DNA-directed DNA polymerase activity
MUY22_30505	COG0789	Transcriptional regulator
MUY22_30515	COG2318	DinB family
MUY22_30520	COG2813	Specifically methylates the guanine in position
MUY22_30535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_30545	COG2079	MmgE PrpD family protein
MUY22_30555	COG2301	Belongs to the HpcH HpaI aldolase family
MUY22_30560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_30575	COG4214	carbohydrate transport
MUY22_30650	COG1131	(ABC) transporter
MUY22_30655	COG1725	Transcriptional regulator
MUY22_30745	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_30775	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MUY22_30780	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_30795	COG0702	epimerase
MUY22_30800	COG1733	regulation of RNA biosynthetic process
MUY22_30805	COG1295	ribonuclease BN
MUY22_30885	COG1674	ftsk spoiiie
MUY22_30905	COG0464	growth
MUY22_30995	COG0477	Major facilitator Superfamily
MUY22_31010	COG1940	carbohydrate kinase activity
MUY22_31015	COG0531	amino acid
MUY22_31020	COG3250	beta-galactosidase activity
MUY22_31025	COG1940	carbohydrate kinase activity
MUY22_31035	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MUY22_31040	COG1609	Transcriptional regulator
MUY22_31050	COG2124	cytochrome p450
MUY22_31100	COG3547	Transposase (IS116 IS110 IS902 family)
MUY22_31125	COG2815	serine threonine protein kinase
MUY22_31125	COG0515	serine threonine protein kinase
MUY22_31165	COG3903	Transcriptional regulator
MUY22_31165	COG3629	intracellular signal transduction
MUY22_31175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUY22_31180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUY22_31190	COG1088	dTDP-glucose 4,6-dehydratase activity
MUY22_31245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_31255	COG0747	negative chemotaxis
MUY22_31265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_31275	COG4172	Belongs to the ABC transporter superfamily
MUY22_31280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_31285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_31290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_31295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_31300	COG3191	aminopeptidase activity
MUY22_31315	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_31325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_31350	COG0723	plastoquinol--plastocyanin reductase activity
MUY22_31370	COG3251	PFAM MbtH domain protein
MUY22_31390	COG2124	cytochrome p450
MUY22_31415	COG0745	RESPONSE REGULATOR receiver
MUY22_31420	COG0745	RESPONSE REGULATOR receiver
MUY22_31445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUY22_31465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_31475	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_31480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_31485	COG1252	NADH dehydrogenase
MUY22_31495	COG0477	Major facilitator Superfamily
MUY22_31505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_31520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_31530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_31570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUY22_31575	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUY22_31620	COG3629	intracellular signal transduction
MUY22_31620	COG3903	Transcriptional regulator
MUY22_31710	COG0714	Associated with various cellular activities
MUY22_31745	COG0791	NLP P60 protein
MUY22_31745	COG1388	LysM domain
MUY22_31745	COG3103	Sh3 type 3 domain protein
MUY22_31795	COG2814	Major facilitator Superfamily
MUY22_31800	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_31815	COG0667	Aldo Keto reductase
MUY22_31830	COG0667	Aldo Keto reductase
MUY22_31835	COG1063	alcohol dehydrogenase
MUY22_31865	COG1902	pentaerythritol trinitrate reductase activity
MUY22_31880	COG0667	Aldo Keto reductase
MUY22_31910	COG1309	transcriptional regulator
MUY22_31940	COG1960	acyl-CoA dehydrogenase activity
MUY22_31950	COG1902	pentaerythritol trinitrate reductase activity
MUY22_31960	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_31975	COG2353	YceI-like domain
MUY22_31980	COG1335	isochorismatase
MUY22_32005	COG0583	DNA-binding transcription factor activity
MUY22_32015	COG1917	Cupin 2, conserved barrel domain protein
MUY22_32035	COG0402	S-adenosylhomocysteine deaminase activity
MUY22_32050	COG0006	proline dipeptidase activity
MUY22_32060	COG1609	Transcriptional regulator
MUY22_32075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUY22_32105	COG1960	acyl-CoA dehydrogenase activity
MUY22_32125	COG0583	DNA-binding transcription factor activity
MUY22_32265	COG1846	Transcriptional regulator
MUY22_32275	COG0477	Major facilitator Superfamily
MUY22_32290	COG2318	DinB family
MUY22_32295	COG1793	dna ligase
MUY22_32325	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MUY22_32340	COG3896	Chloramphenicol phosphotransferase-like protein
MUY22_32345	COG0739	heme binding
MUY22_32350	COG2855	membrane
MUY22_32360	COG0583	DNA-binding transcription factor activity
MUY22_32400	COG0439	Biotin carboxylase
MUY22_32440	COG3284	Transcriptional regulator
MUY22_32455	COG0477	Major facilitator Superfamily
MUY22_32470	COG0583	DNA-binding transcription factor activity
MUY22_32480	COG0006	proline dipeptidase activity
MUY22_32510	COG3938	Belongs to the proline racemase family
MUY22_32535	COG0154	amidase activity
MUY22_32635	COG0778	Nitroreductase
MUY22_32635	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MUY22_32640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MUY22_32655	COG0475	glutathione-regulated potassium exporter activity
MUY22_32700	COG2197	response regulator
MUY22_32705	COG4585	Histidine kinase
MUY22_32750	COG2207	Transcriptional regulator
MUY22_32755	COG0154	amidase activity
MUY22_32795	COG0604	alcohol dehydrogenase
MUY22_32795	COG3321	synthase
MUY22_32815	COG2814	Major facilitator Superfamily
MUY22_32910	COG1174	glycine betaine transport
MUY22_32975	COG2814	Major facilitator Superfamily
MUY22_32980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUY22_32985	COG3158	transport of potassium into the cell
MUY22_33005	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MUY22_33005	COG1672	PFAM Archaeal ATPase
MUY22_33010	COG3903	Transcriptional regulator
MUY22_33010	COG3629	intracellular signal transduction
MUY22_33025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_33035	COG3629	intracellular signal transduction
MUY22_33055	COG0367	asparagine synthase
MUY22_33060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUY22_33060	COG0300	oxidoreductase activity
MUY22_33060	COG4221	oxidoreductase activity
MUY22_33060	COG3321	synthase
MUY22_33070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_33070	COG4221	oxidoreductase activity
MUY22_33070	COG3321	synthase
MUY22_33070	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_33070	COG3321	synthase
MUY22_33070	COG4221	oxidoreductase activity
MUY22_33070	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_33070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_33075	COG2070	2-Nitropropane dioxygenase
MUY22_33075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MUY22_33080	COG2124	cytochrome p450
MUY22_33085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUY22_33085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_33085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUY22_33085	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_33085	COG3321	synthase
MUY22_33090	COG2124	cytochrome p450
MUY22_33110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_33115	COG3250	beta-galactosidase activity
MUY22_33160	COG3546	catalase activity
MUY22_33165	COG3546	catalase activity
MUY22_33200	COG1414	Transcriptional regulator
MUY22_33205	COG0747	negative chemotaxis
MUY22_33210	COG0601	transmembrane transport
MUY22_33215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_33220	COG0444	Belongs to the ABC transporter superfamily
MUY22_33255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_33260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_33275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_33335	COG0456	acetyltransferase
MUY22_33360	COG0702	epimerase
MUY22_33405	COG2855	membrane
MUY22_33410	COG0583	DNA-binding transcription factor activity
MUY22_33450	COG1131	(ABC) transporter
MUY22_33460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUY22_33485	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_33505	COG2409	Drug exporters of the RND superfamily
MUY22_33515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUY22_33520	COG0477	Major facilitator Superfamily
MUY22_33525	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_33535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_33605	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MUY22_33625	COG0300	oxidoreductase activity
MUY22_33630	COG2226	methyltransferase
MUY22_33640	COG3250	beta-galactosidase activity
MUY22_33650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MUY22_33655	COG1510	regulation of RNA biosynthetic process
MUY22_33675	COG0702	epimerase
MUY22_33700	COG1621	beta-fructofuranosidase activity
MUY22_33705	COG4221	oxidoreductase activity
MUY22_33715	COG3511	phospholipase C
MUY22_33730	COG2132	Multicopper oxidase
MUY22_33760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUY22_33815	COG1302	Protein conserved in bacteria
MUY22_33850	COG0148	phosphopyruvate hydratase activity
MUY22_33880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_33885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_33920	COG1309	transcriptional regulator
MUY22_33925	COG2272	Belongs to the type-B carboxylesterase lipase family
MUY22_33930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_33970	COG1595	DNA-templated transcription, initiation
MUY22_33980	COG2261	transglycosylase associated protein
MUY22_34000	COG4585	Histidine kinase
MUY22_34005	COG2197	response regulator
MUY22_34020	COG3246	L-lysine catabolic process to acetate
MUY22_34045	COG0477	Major facilitator Superfamily
MUY22_34050	COG0167	dihydroorotate dehydrogenase activity
MUY22_34070	COG1595	DNA-templated transcription, initiation
MUY22_34100	COG0596	Alpha beta hydrolase
MUY22_34145	COG0395	ABC-type sugar transport system, permease component
MUY22_34150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_34200	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_34225	COG3387	PFAM Glycoside hydrolase 15-related
MUY22_34230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MUY22_34235	COG5640	endopeptidase activity
MUY22_34250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUY22_34290	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_34295	COG1309	transcriptional regulator
MUY22_34305	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_34310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_34320	COG1024	Enoyl-CoA hydratase
MUY22_34335	COG0596	Alpha beta hydrolase
MUY22_34350	COG0657	acetylesterase activity
MUY22_34360	COG1175	transmembrane transport
MUY22_34390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MUY22_34395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_34400	COG2301	Belongs to the HpcH HpaI aldolase family
MUY22_34435	COG2072	flavoprotein involved in K transport
MUY22_34455	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MUY22_34470	COG4948	Mandelate Racemase Muconate Lactonizing
MUY22_34490	COG0601	transmembrane transport
MUY22_34495	COG0444	Belongs to the ABC transporter superfamily
MUY22_34500	COG4608	Belongs to the ABC transporter superfamily
MUY22_34520	COG0477	Major facilitator Superfamily
MUY22_34545	COG2188	Transcriptional regulator
MUY22_34550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MUY22_34575	COG0477	Major facilitator Superfamily
MUY22_34585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUY22_34645	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_34655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUY22_34705	COG0745	RESPONSE REGULATOR receiver
MUY22_34710	COG2205	protein histidine kinase activity
MUY22_34715	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MUY22_34720	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUY22_34735	COG4221	oxidoreductase activity
MUY22_34740	COG3631	Ketosteroid isomerase-related protein
MUY22_34750	COG2205	protein histidine kinase activity
MUY22_34755	COG0745	RESPONSE REGULATOR receiver
MUY22_34770	COG1131	(ABC) transporter
MUY22_34775	COG4941	Belongs to the sigma-70 factor family
MUY22_34790	COG1309	transcriptional regulator
MUY22_34805	COG2267	carboxylic ester hydrolase activity
MUY22_34830	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUY22_34910	COG3845	ABC transporter
MUY22_34940	COG0765	amino acid transport
MUY22_34980	COG0596	Alpha beta hydrolase
MUY22_34995	COG4948	Mandelate Racemase Muconate Lactonizing
MUY22_35000	COG2186	Transcriptional regulator
MUY22_35015	COG0395	ABC-type sugar transport system, permease component
MUY22_35020	COG4948	Mandelate Racemase Muconate Lactonizing
MUY22_35025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MUY22_35040	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_35045	COG4221	oxidoreductase activity
MUY22_35070	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_35185	COG4941	Belongs to the sigma-70 factor family
MUY22_35190	COG3795	YCII-related domain
MUY22_35205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUY22_35210	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MUY22_35210	COG1082	Xylose isomerase domain protein TIM barrel
MUY22_35215	COG0583	DNA-binding transcription factor activity
MUY22_35295	COG1309	transcriptional regulator
MUY22_35310	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MUY22_35310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_35315	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_35340	COG1278	Cold shock
MUY22_35365	COG3285	dna ligase
MUY22_35365	COG1793	dna ligase
MUY22_35385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUY22_35400	COG2267	carboxylic ester hydrolase activity
MUY22_35445	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MUY22_35470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUY22_35480	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_35485	COG1609	Transcriptional regulator
MUY22_35495	COG1175	transmembrane transport
MUY22_35510	COG1609	Transcriptional regulator
MUY22_35530	COG1278	Cold shock
MUY22_35535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MUY22_35555	COG0823	Involved in the tonB-independent uptake of proteins
MUY22_35555	COG1506	peptidase
MUY22_35555	COG4946	Tricorn protease homolog
MUY22_35570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUY22_35575	COG1802	Transcriptional regulator
MUY22_35580	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUY22_35590	COG3903	Transcriptional regulator
MUY22_35590	COG3629	intracellular signal transduction
MUY22_35595	COG5002	protein histidine kinase activity
MUY22_35595	COG0784	Response regulator, receiver
MUY22_35595	COG2205	protein histidine kinase activity
MUY22_35610	COG0387	Pfam Sodium calcium exchanger
MUY22_35620	COG0535	radical SAM domain protein
MUY22_35635	COG3284	Transcriptional regulator
MUY22_35700	COG3250	beta-galactosidase activity
MUY22_35705	COG1609	Transcriptional regulator
MUY22_35710	COG1129	ABC transporter
MUY22_35720	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_35730	COG3254	rhamnose metabolic process
MUY22_35740	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_35740	COG3347	Dehydrogenase
MUY22_35750	COG1070	Carbohydrate kinase
MUY22_35760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MUY22_35765	COG2197	response regulator
MUY22_35770	COG4585	Histidine kinase
MUY22_35825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUY22_35855	COG0583	DNA-binding transcription factor activity
MUY22_35880	COG0045	succinate-CoA ligase (ADP-forming) activity
MUY22_35890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_35905	COG1802	Transcriptional regulator
MUY22_35910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MUY22_35920	COG3622	Belongs to the hyi family
MUY22_35925	COG2084	Dehydrogenase
MUY22_35930	COG3960	tartronate-semialdehyde synthase activity
MUY22_35945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUY22_35950	COG0590	tRNA wobble adenosine to inosine editing
MUY22_35955	COG2252	PERMEase
MUY22_35965	COG1929	Belongs to the glycerate kinase type-1 family
MUY22_36035	COG2066	Belongs to the glutaminase family
MUY22_36045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUY22_36060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUY22_36065	COG0596	Alpha beta hydrolase
MUY22_36090	COG1793	dna ligase
MUY22_36090	COG3285	dna ligase
MUY22_36095	COG0183	Belongs to the thiolase family
MUY22_36110	COG1090	epimerase
MUY22_36120	COG1309	transcriptional regulator
MUY22_36135	COG2267	carboxylic ester hydrolase activity
MUY22_36160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MUY22_36175	COG1349	DNA-binding transcription factor activity
MUY22_36200	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUY22_36235	COG2197	response regulator
MUY22_36240	COG2197	response regulator
MUY22_36245	COG1105	Belongs to the carbohydrate kinase PfkB family
MUY22_36260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUY22_36265	COG1063	alcohol dehydrogenase
MUY22_36270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUY22_36280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MUY22_36295	COG3321	synthase
MUY22_36295	COG0604	alcohol dehydrogenase
MUY22_36345	COG0604	alcohol dehydrogenase
MUY22_36345	COG3321	synthase
MUY22_36365	COG0148	phosphopyruvate hydratase activity
MUY22_36375	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_36380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_36410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUY22_36415	COG2267	carboxylic ester hydrolase activity
MUY22_36445	COG0667	Aldo Keto reductase
MUY22_36450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_36455	COG1968	undecaprenyl-diphosphatase activity
MUY22_36465	COG0339	signal peptide processing
MUY22_36470	COG0740	serine-type endopeptidase activity
MUY22_36475	COG4257	antibiotic catabolic process
MUY22_36480	COG0039	L-malate dehydrogenase activity
MUY22_36485	COG1846	Transcriptional regulator
MUY22_36510	COG0596	Alpha beta hydrolase
MUY22_36520	COG3537	Alpha-1,2-mannosidase
MUY22_36535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUY22_36540	COG2362	D-Aminopeptidase
MUY22_36545	COG0747	negative chemotaxis
MUY22_36550	COG0601	transmembrane transport
MUY22_36555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_36580	COG1619	proteins homologs of microcin C7 resistance protein MccF
MUY22_36625	COG0477	Major facilitator Superfamily
MUY22_36645	COG0640	Transcriptional regulator
MUY22_36655	COG1309	transcriptional regulator
MUY22_36665	COG2226	methyltransferase
MUY22_36690	COG4941	Belongs to the sigma-70 factor family
MUY22_36700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MUY22_36725	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_36750	COG4122	O-methyltransferase activity
MUY22_36765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_36770	COG0384	phenazine biosynthesis protein PhzF
MUY22_36785	COG4941	Belongs to the sigma-70 factor family
MUY22_36790	COG3795	YCII-related domain
MUY22_36800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MUY22_36850	COG2267	carboxylic ester hydrolase activity
MUY22_36855	COG4941	Belongs to the sigma-70 factor family
MUY22_36865	COG2124	cytochrome p450
MUY22_36885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MUY22_36895	COG2318	DinB family
MUY22_36905	COG1309	transcriptional regulator
MUY22_36910	COG1960	acyl-CoA dehydrogenase activity
MUY22_36915	COG1309	transcriptional regulator
MUY22_36945	COG1396	sequence-specific DNA binding
MUY22_36955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MUY22_36985	COG1435	thymidine kinase activity
MUY22_36995	COG0494	nUDIX hydrolase
MUY22_37000	COG1349	DNA-binding transcription factor activity
MUY22_37005	COG2226	methyltransferase
MUY22_37010	COG0463	Glycosyl transferase, family 2
MUY22_37020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUY22_37040	COG3321	synthase
MUY22_37040	COG0604	alcohol dehydrogenase
MUY22_37085	COG0083	homoserine kinase activity
MUY22_37090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_37110	COG0069	glutamate synthase activity
MUY22_37115	COG0017	Asparaginyl-tRNA synthetase
MUY22_37150	COG0402	S-adenosylhomocysteine deaminase activity
MUY22_37155	COG1414	Transcriptional regulator
MUY22_37160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_37170	COG3485	protocatechuate 3,4-dioxygenase
MUY22_37180	COG3979	chitinase
MUY22_37190	COG1136	(ABC) transporter
MUY22_37195	COG1136	(ABC) transporter
MUY22_37200	COG4221	oxidoreductase activity
MUY22_37205	COG0583	DNA-binding transcription factor activity
MUY22_37210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MUY22_37215	COG1309	transcriptional regulator
MUY22_37250	COG4552	Acetyltransferase involved in intracellular survival and related
MUY22_37280	COG1597	lipid kinase activity
MUY22_37285	COG0805	protein transport
MUY22_37290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MUY22_37300	COG2378	regulation of single-species biofilm formation
MUY22_37310	COG1733	regulation of RNA biosynthetic process
MUY22_37320	COG4221	oxidoreductase activity
MUY22_37330	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MUY22_37335	COG1597	lipid kinase activity
MUY22_37345	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MUY22_37350	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MUY22_37405	COG1222	aaa ATPase
MUY22_37425	COG1994	Peptidase M50
MUY22_37425	COG0517	IMP dehydrogenase activity
MUY22_37440	COG1192	Involved in chromosome partitioning
MUY22_37445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MUY22_37450	COG0140	phosphoribosyl-ATP diphosphatase activity
MUY22_37465	COG0560	Phosphoserine phosphatase
MUY22_37485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MUY22_37490	COG2814	Major facilitator Superfamily
MUY22_37505	COG0488	(ABC) transporter
MUY22_37510	COG0215	cysteine-tRNA ligase activity
MUY22_37515	COG0789	Transcriptional regulator
MUY22_37535	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MUY22_37545	COG2226	methyltransferase
MUY22_37550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MUY22_37565	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MUY22_37575	COG0477	Major facilitator Superfamily
MUY22_37580	COG0745	RESPONSE REGULATOR receiver
MUY22_37585	COG2205	protein histidine kinase activity
MUY22_37600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MUY22_37610	COG2304	oxidoreductase activity
MUY22_37620	COG0714	Associated with various cellular activities
MUY22_37640	COG3883	PFAM NLP P60 protein
MUY22_37640	COG0791	NLP P60 protein
MUY22_37645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MUY22_37650	COG2267	carboxylic ester hydrolase activity
MUY22_37655	COG1285	pathogenesis
MUY22_37670	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MUY22_37680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MUY22_37690	COG0583	DNA-binding transcription factor activity
MUY22_37695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MUY22_37700	COG2267	carboxylic ester hydrolase activity
MUY22_37760	COG0656	L-ascorbic acid biosynthetic process
MUY22_37780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUY22_37795	COG1088	dTDP-glucose 4,6-dehydratase activity
MUY22_37800	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUY22_37800	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUY22_37815	COG3118	belongs to the thioredoxin family
MUY22_37820	COG0789	Transcriptional regulator
MUY22_37835	COG1716	ATPase activity
MUY22_37840	COG0509	glycine decarboxylation via glycine cleavage system
MUY22_37865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUY22_37870	COG1024	Enoyl-CoA hydratase
MUY22_37880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUY22_37880	COG1648	precorrin-2 dehydrogenase activity
MUY22_37900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MUY22_37905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUY22_37910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUY22_37915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MUY22_37935	COG0523	cobalamin synthesis protein
MUY22_37950	COG2814	Major facilitator Superfamily
MUY22_37965	COG0076	glutamate decarboxylase activity
MUY22_37970	COG2211	Major facilitator Superfamily
MUY22_37985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_38030	COG1116	anion transmembrane transporter activity
MUY22_38035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUY22_38040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_38055	COG1132	(ABC) transporter
MUY22_38060	COG1132	(ABC) transporter
MUY22_38065	COG0583	DNA-binding transcription factor activity
MUY22_38085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MUY22_38095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUY22_38100	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUY22_38105	COG1120	ATPase activity
MUY22_38110	COG2318	DinB family
MUY22_38115	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MUY22_38135	COG0488	(ABC) transporter
MUY22_38165	COG4974	Belongs to the 'phage' integrase family
MUY22_38215	COG1674	ftsk spoiiie
MUY22_38250	COG2188	Transcriptional regulator
MUY22_38255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MUY22_38270	COG4974	Belongs to the 'phage' integrase family
MUY22_38335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MUY22_38345	COG4585	Histidine kinase
MUY22_38350	COG2197	response regulator
MUY22_38365	COG3250	beta-galactosidase activity
MUY22_38385	COG0222	ribosome binding
MUY22_38420	COG2367	Beta-lactamase
MUY22_38435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUY22_38445	COG2249	NAD(P)H dehydrogenase (quinone) activity
MUY22_38485	COG3321	synthase
MUY22_38485	COG4221	oxidoreductase activity
MUY22_38485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_38485	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_38535	COG0596	Alpha beta hydrolase
MUY22_38540	COG1309	transcriptional regulator
MUY22_38590	COG2208	phosphoserine phosphatase activity
MUY22_38590	COG2770	Histidine kinase
MUY22_38605	COG2409	Drug exporters of the RND superfamily
MUY22_38625	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MUY22_38650	COG1846	Transcriptional regulator
MUY22_38750	COG2814	Major facilitator Superfamily
MUY22_38790	COG0667	Aldo Keto reductase
MUY22_38815	COG0456	acetyltransferase
MUY22_38820	COG5297	Belongs to the glycosyl hydrolase family 6
MUY22_38825	COG5297	Belongs to the glycosyl hydrolase family 6
MUY22_38830	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MUY22_38835	COG5297	Belongs to the glycosyl hydrolase family 6
MUY22_38835	COG4733	cellulase activity
MUY22_38855	COG0395	ABC-type sugar transport system, permease component
MUY22_38860	COG2723	6-phospho-beta-galactosidase activity
MUY22_38865	COG0129	dihydroxy-acid dehydratase activity
MUY22_38875	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MUY22_38935	COG0656	L-ascorbic acid biosynthetic process
MUY22_38970	COG0583	DNA-binding transcription factor activity
MUY22_38975	COG0019	diaminopimelate decarboxylase activity
MUY22_39015	COG3209	COG3209 Rhs family protein
MUY22_39090	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_39105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_39110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_39120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUY22_39135	COG1280	lysine exporter protein (LysE YggA)
MUY22_39175	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MUY22_39185	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MUY22_39205	COG2018	Roadblock/LC7 domain
MUY22_39235	COG1793	dna ligase
MUY22_39235	COG3285	dna ligase
MUY22_39250	COG3629	intracellular signal transduction
MUY22_39250	COG3903	Transcriptional regulator
MUY22_39280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_39290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUY22_39310	COG1082	Xylose isomerase domain protein TIM barrel
MUY22_39315	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MUY22_39320	COG1024	Enoyl-CoA hydratase
MUY22_39340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MUY22_39345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUY22_39350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUY22_39360	COG1862	Preprotein translocase
MUY22_39365	COG2255	four-way junction helicase activity
MUY22_39375	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MUY22_39390	COG0217	transcriptional regulatory protein
MUY22_39395	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MUY22_39410	COG1396	sequence-specific DNA binding
MUY22_39415	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MUY22_39425	COG0277	FAD linked oxidase domain protein
MUY22_39435	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MUY22_39435	COG3608	succinylglutamate desuccinylase aspartoacylase
MUY22_39455	COG0438	transferase activity, transferring glycosyl groups
MUY22_39480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MUY22_39485	COG0778	Nitroreductase
MUY22_39555	COG1335	isochorismatase
MUY22_39580	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MUY22_39655	COG2201	protein-glutamate methylesterase activity
MUY22_39700	COG0297	glycogen (starch) synthase activity
MUY22_39715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MUY22_39745	COG3046	protein related to deoxyribodipyrimidine photolyase
MUY22_39750	COG2770	Histidine kinase
MUY22_39750	COG2208	phosphoserine phosphatase activity
MUY22_39770	COG0297	glycogen (starch) synthase activity
MUY22_39800	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_39835	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_39865	COG0604	alcohol dehydrogenase
MUY22_39865	COG3321	synthase
MUY22_39870	COG2188	Transcriptional regulator
MUY22_39905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUY22_39960	COG0142	geranyltranstransferase activity
MUY22_40035	COG4124	Belongs to the glycosyl hydrolase 26 family
MUY22_40050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUY22_40055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUY22_40080	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUY22_40090	COG1960	acyl-CoA dehydrogenase activity
MUY22_40105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUY22_40150	COG3903	Transcriptional regulator
MUY22_40150	COG3629	intracellular signal transduction
MUY22_40170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUY22_40175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUY22_40180	COG1216	Glycosyl transferase, family 2
MUY22_40190	COG1309	transcriptional regulator
MUY22_40255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MUY22_40270	COG3250	beta-galactosidase activity
MUY22_40300	COG2205	protein histidine kinase activity
MUY22_40305	COG0745	RESPONSE REGULATOR receiver
MUY22_40330	COG1216	Glycosyl transferase, family 2
MUY22_40335	COG0297	glycogen (starch) synthase activity
MUY22_40355	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_40355	COG3321	synthase
MUY22_40355	COG0604	alcohol dehydrogenase
MUY22_40395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_40400	COG1090	epimerase
MUY22_40405	COG0583	DNA-binding transcription factor activity
MUY22_40425	COG3903	Transcriptional regulator
MUY22_40425	COG3629	intracellular signal transduction
MUY22_40440	COG0673	inositol 2-dehydrogenase activity
MUY22_40445	COG0673	inositol 2-dehydrogenase activity
MUY22_40455	COG0395	ABC-type sugar transport system, permease component
MUY22_40460	COG1175	transmembrane transport
MUY22_40465	COG1653	transport
MUY22_40470	COG0277	FAD linked oxidase domain protein
MUY22_40495	COG3321	synthase
MUY22_40495	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_40495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUY22_40495	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_40495	COG0300	oxidoreductase activity
MUY22_40525	COG0604	alcohol dehydrogenase
MUY22_40530	COG0137	argininosuccinate synthase activity
MUY22_40540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUY22_40545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MUY22_40555	COG1414	Transcriptional regulator
MUY22_40560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MUY22_40565	COG2226	methyltransferase
MUY22_40580	COG4214	carbohydrate transport
MUY22_40585	COG1129	ABC transporter
MUY22_40595	COG2160	L-arabinose isomerase activity
MUY22_40635	COG3511	phospholipase C
MUY22_40645	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_40665	COG1609	Transcriptional regulator
MUY22_40680	COG2182	Extracellular solute-binding protein
MUY22_40685	COG1175	transmembrane transport
MUY22_40690	COG0395	ABC-type sugar transport system, permease component
MUY22_40700	COG2188	Transcriptional regulator
MUY22_40715	COG0302	gtp cyclohydrolase
MUY22_40775	COG4991	sh3 domain protein
MUY22_40785	COG0395	ABC-type sugar transport system, permease component
MUY22_40790	COG1175	transmembrane transport
MUY22_40795	COG2182	Extracellular solute-binding protein
MUY22_40800	COG0477	Major facilitator Superfamily
MUY22_40810	COG2181	nitrate reductase activity
MUY22_40810	COG0247	lactate metabolic process
MUY22_40820	COG0778	Nitroreductase
MUY22_40820	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MUY22_40825	COG5001	Diguanylate cyclase
MUY22_40825	COG1716	ATPase activity
MUY22_40835	COG2124	cytochrome p450
MUY22_40845	COG1609	Transcriptional regulator
MUY22_40855	COG1175	transmembrane transport
MUY22_40905	COG2353	YceI-like domain
MUY22_40915	COG0435	Glutathione S-transferase
MUY22_40925	COG0596	Alpha beta hydrolase
MUY22_40945	COG1819	glycosyl
MUY22_40950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_40955	COG3973	AAA domain
MUY22_40970	COG0459	protein refolding
MUY22_41040	COG0702	epimerase
MUY22_41060	COG0596	Alpha beta hydrolase
MUY22_41085	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUY22_41120	COG2201	protein-glutamate methylesterase activity
MUY22_41145	COG0326	Molecular chaperone. Has ATPase activity
MUY22_41160	COG2815	serine threonine protein kinase
MUY22_41160	COG0515	serine threonine protein kinase
MUY22_41185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUY22_41190	COG4608	Belongs to the ABC transporter superfamily
MUY22_41205	COG4166	transmembrane transport
MUY22_41210	COG2186	Transcriptional regulator
MUY22_41235	COG2124	cytochrome p450
MUY22_41240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MUY22_41320	COG2890	protein-(glutamine-N5) methyltransferase activity
MUY22_41335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MUY22_41355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MUY22_41365	COG0583	DNA-binding transcription factor activity
MUY22_41380	COG2267	carboxylic ester hydrolase activity
MUY22_41410	COG0542	response to heat
MUY22_41530	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MUY22_41535	COG1335	isochorismatase
MUY22_41540	COG0473	3-isopropylmalate dehydrogenase activity
MUY22_41565	COG1064	alcohol dehydrogenase
MUY22_41570	COG1309	transcriptional regulator
MUY22_41580	COG2378	regulation of single-species biofilm formation
MUY22_41605	COG3321	synthase
MUY22_41605	COG0604	alcohol dehydrogenase
MUY22_41610	COG1309	transcriptional regulator
MUY22_41615	COG0604	alcohol dehydrogenase
MUY22_41625	COG0024	Methionine aminopeptidase
MUY22_41640	COG3285	dna ligase
MUY22_41640	COG1793	dna ligase
MUY22_41670	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MUY22_41760	COG3285	dna ligase
MUY22_41760	COG1793	dna ligase
MUY22_41770	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUY22_41775	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUY22_41785	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_41790	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_41795	COG1228	amidohydrolase
MUY22_41815	COG1414	Transcriptional regulator
MUY22_41820	COG2814	Major facilitator Superfamily
MUY22_41860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_41870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MUY22_41875	COG0655	NAD(P)H dehydrogenase (quinone) activity
MUY22_41930	COG3629	intracellular signal transduction
MUY22_41930	COG3903	Transcriptional regulator
MUY22_41975	COG3903	Transcriptional regulator
MUY22_41975	COG3629	intracellular signal transduction
MUY22_41990	COG2124	cytochrome p450
MUY22_42000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MUY22_42020	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_42025	COG0604	alcohol dehydrogenase
MUY22_42025	COG3321	synthase
MUY22_42035	COG2124	cytochrome p450
MUY22_42080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUY22_42085	COG0156	8-amino-7-oxononanoate synthase activity
MUY22_42095	COG2197	response regulator
MUY22_42095	COG3903	Transcriptional regulator
MUY22_42100	COG3209	COG3209 Rhs family protein
MUY22_42115	COG2364	Membrane
MUY22_42120	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MUY22_42135	COG0667	Aldo Keto reductase
MUY22_42140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MUY22_42145	COG3321	synthase
MUY22_42145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MUY22_42145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MUY22_42145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUY22_42155	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MUY22_42170	COG0019	diaminopimelate decarboxylase activity
MUY22_42175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUY22_42210	COG0583	DNA-binding transcription factor activity
MUY22_42260	COG0405	Gamma-glutamyltransferase
MUY22_42265	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_42285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUY22_42290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUY22_42295	COG2226	methyltransferase
MUY22_42300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MUY22_42320	COG0601	transmembrane transport
MUY22_42325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUY22_42375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUY22_42420	COG0667	Aldo Keto reductase
MUY22_42440	COG1960	acyl-CoA dehydrogenase activity
MUY22_42450	COG1309	transcriptional regulator
MUY22_42470	COG1902	pentaerythritol trinitrate reductase activity
MUY22_42475	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MUY22_42485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_42490	COG1309	transcriptional regulator
MUY22_42500	COG1404	Belongs to the peptidase S8 family
MUY22_42535	COG4585	Histidine kinase
MUY22_42580	COG3250	beta-galactosidase activity
MUY22_42595	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_42600	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_42610	COG1879	ABC-type sugar transport system periplasmic component
MUY22_42625	COG3693	PFAM glycoside hydrolase, family 10
MUY22_42700	COG0596	Alpha beta hydrolase
MUY22_42715	COG4941	Belongs to the sigma-70 factor family
MUY22_42720	COG3795	YCII-related domain
MUY22_42735	COG0604	alcohol dehydrogenase
MUY22_42735	COG3321	synthase
MUY22_42740	COG0604	alcohol dehydrogenase
MUY22_42740	COG3321	synthase
MUY22_42775	COG1846	Transcriptional regulator
MUY22_42790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUY22_42845	COG3831	ATPase activity
MUY22_42850	COG0714	Associated with various cellular activities
MUY22_42855	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MUY22_42860	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MUY22_42865	COG4715	Zinc finger, swim domain protein
MUY22_42875	COG0596	Alpha beta hydrolase
MUY22_42940	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUY22_42945	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MUY22_42970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUY22_43010	COG1309	transcriptional regulator
MUY22_43015	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_43035	COG0477	Major facilitator Superfamily
MUY22_43050	COG1309	transcriptional regulator
MUY22_43065	COG3585	molybdate ion transport
MUY22_43070	COG2080	2 iron, 2 sulfur cluster binding
MUY22_43075	COG2010	Cytochrome c
MUY22_43075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUY22_43135	COG1349	DNA-binding transcription factor activity
MUY22_43140	COG2222	sugar isomerase
MUY22_43155	COG1105	Belongs to the carbohydrate kinase PfkB family
MUY22_43195	COG2124	cytochrome p450
MUY22_43300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_43320	COG0583	DNA-binding transcription factor activity
MUY22_43330	COG2755	lipolytic protein G-D-S-L family
MUY22_43330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MUY22_43340	COG2205	protein histidine kinase activity
MUY22_43345	COG0745	RESPONSE REGULATOR receiver
MUY22_43370	COG1309	transcriptional regulator
MUY22_43380	COG0477	Major facilitator Superfamily
MUY22_43390	COG1957	nucleoside hydrolase
MUY22_43410	COG2124	cytochrome p450
MUY22_43425	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MUY22_43455	COG0028	Belongs to the TPP enzyme family
MUY22_43470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUY22_43480	COG1472	Belongs to the glycosyl hydrolase 3 family
MUY22_43485	COG1609	Transcriptional regulator
MUY22_43490	COG1349	DNA-binding transcription factor activity
MUY22_43510	COG0702	epimerase
MUY22_43515	COG0702	epimerase
MUY22_43520	COG1309	transcriptional regulator
MUY22_43635	COG2197	response regulator
MUY22_43640	COG2957	Belongs to the agmatine deiminase family
MUY22_43645	COG1309	transcriptional regulator
MUY22_43655	COG4191	Histidine kinase
MUY22_43660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_43720	COG0494	nUDIX hydrolase
MUY22_43725	COG0235	Class ii aldolase
MUY22_43745	COG1011	Hydrolase
MUY22_43750	COG0494	nUDIX hydrolase
MUY22_43760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUY22_43760	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MUY22_43765	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MUY22_43770	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MUY22_43810	COG0494	nUDIX hydrolase
MUY22_43815	COG0542	response to heat
MUY22_43895	COG1674	ftsk spoiiie
MUY22_43915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_43960	COG0154	amidase activity
MUY22_43985	COG0738	Major facilitator superfamily
MUY22_44000	COG0673	inositol 2-dehydrogenase activity
MUY22_44035	COG1131	(ABC) transporter
MUY22_44040	COG1725	Transcriptional regulator
MUY22_44045	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MUY22_44050	COG0028	Belongs to the TPP enzyme family
MUY22_44095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MUY22_44105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUY22_44125	COG0702	epimerase
MUY22_44135	COG0583	DNA-binding transcription factor activity
MUY22_44150	COG0667	Aldo Keto reductase
MUY22_44155	COG0583	DNA-binding transcription factor activity
MUY22_44160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUY22_44250	COG4221	oxidoreductase activity
MUY22_44320	COG5002	protein histidine kinase activity
MUY22_44325	COG0745	RESPONSE REGULATOR receiver
MUY22_44335	COG0667	Aldo Keto reductase
MUY22_44365	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_44400	COG2267	carboxylic ester hydrolase activity
MUY22_44410	COG1609	Transcriptional regulator
MUY22_44425	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_44485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUY22_44515	COG0748	coenzyme F420 binding
MUY22_44545	COG1012	belongs to the aldehyde dehydrogenase family
MUY22_44565	COG0456	acetyltransferase
MUY22_44575	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MUY22_44595	COG3511	phospholipase C
MUY22_44645	COG0604	alcohol dehydrogenase
MUY22_44665	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_44695	COG0596	Alpha beta hydrolase
MUY22_44700	COG0473	3-isopropylmalate dehydrogenase activity
MUY22_44705	COG0583	DNA-binding transcription factor activity
MUY22_44720	COG0714	Associated with various cellular activities
MUY22_44730	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MUY22_44735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUY22_44745	COG5492	domain, Protein
MUY22_44760	COG4948	Mandelate Racemase Muconate Lactonizing
MUY22_44765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUY22_44775	COG1414	Transcriptional regulator
MUY22_44780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUY22_44795	COG2197	response regulator
MUY22_44850	COG1160	GTP binding
MUY22_44880	COG0475	glutathione-regulated potassium exporter activity
MUY22_44885	COG2936	dipeptidyl-peptidase activity
MUY22_44900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MUY22_44930	COG0494	nUDIX hydrolase
MUY22_44935	COG0504	CTP synthase activity
MUY22_44945	COG1802	Transcriptional regulator
MUY22_44950	COG1953	Uracil, thiamine, allantoin
MUY22_45000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUY22_45015	COG0647	UMP catabolic process
MUY22_45045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MUY22_45050	COG2094	Belongs to the DNA glycosylase MPG family
MUY22_45055	COG0165	Argininosuccinate lyase
MUY22_45060	COG0137	argininosuccinate synthase activity
MUY22_45070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUY22_45075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUY22_45080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MUY22_45085	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MUY22_45090	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MUY22_45120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUY22_45120	COG0072	phenylalanine-tRNA ligase activity
MUY22_45125	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MUY22_45130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUY22_45135	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MUY22_45140	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MUY22_45160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MUY22_45165	COG0251	oxidation-reduction process
MUY22_45185	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MUY22_45190	COG2610	gluconate transmembrane transporter activity
MUY22_45195	COG2706	6-phosphogluconolactonase activity
MUY22_45205	COG1175	transmembrane transport
MUY22_45210	COG0395	ABC-type sugar transport system, permease component
MUY22_45230	COG0402	S-adenosylhomocysteine deaminase activity
MUY22_45240	COG4565	transcriptional regulatory protein
MUY22_45245	COG3290	protein histidine kinase activity
MUY22_45250	COG1301	dicarboxylic acid transport
MUY22_45255	COG1733	regulation of RNA biosynthetic process
MUY22_45300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUY22_45330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUY22_45335	COG0328	RNA-DNA hybrid ribonuclease activity
MUY22_45340	COG3012	SEC-C Motif Domain Protein
MUY22_45350	COG3250	beta-galactosidase activity
MUY22_45355	COG2272	Belongs to the type-B carboxylesterase lipase family
MUY22_45375	COG0406	alpha-ribazole phosphatase activity
MUY22_45405	COG1609	Transcriptional regulator
MUY22_45425	COG4946	Tricorn protease homolog
MUY22_45425	COG1506	peptidase
MUY22_45425	COG0823	Involved in the tonB-independent uptake of proteins
MUY22_45435	COG1131	(ABC) transporter
MUY22_45500	COG1131	(ABC) transporter
MUY22_45515	COG4585	Histidine kinase
MUY22_45515	COG2203	Gaf domain
MUY22_45520	COG2197	response regulator
MUY22_45525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MUY22_45525	COG0237	dephospho-CoA kinase activity
MUY22_45555	COG0539	negative regulation of cytoplasmic translation
MUY22_45560	COG2226	methyltransferase
MUY22_45580	COG1511	domain protein
MUY22_45610	COG0583	DNA-binding transcription factor activity
MUY22_45625	COG0559	Belongs to the binding-protein-dependent transport system permease family
MUY22_45675	COG2072	flavoprotein involved in K transport
MUY22_45690	COG0583	DNA-binding transcription factor activity
MUY22_45705	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_45760	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MUY22_45765	COG1971	Probably functions as a manganese efflux pump
MUY22_45775	COG0535	radical SAM domain protein
MUY22_45785	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MUY22_45790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MUY22_45815	COG1595	DNA-templated transcription, initiation
MUY22_45855	COG1595	DNA-templated transcription, initiation
MUY22_45900	COG2255	four-way junction helicase activity
MUY22_45970	COG0784	Response regulator, receiver
MUY22_45975	COG4251	negative regulation of phosphorylation
MUY22_45990	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_45995	COG0583	DNA-binding transcription factor activity
MUY22_46025	COG0477	Major facilitator Superfamily
MUY22_46035	COG2159	amidohydrolase
MUY22_46045	COG0477	Major facilitator Superfamily
MUY22_46045	COG2814	Major facilitator Superfamily
MUY22_46070	COG2080	2 iron, 2 sulfur cluster binding
MUY22_46075	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MUY22_46080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUY22_46085	COG0277	FAD linked oxidase domain protein
MUY22_46095	COG4585	Histidine kinase
MUY22_46110	COG1214	PFAM Peptidase M22, glycoprotease
MUY22_46110	COG0456	acetyltransferase
MUY22_46150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUY22_46150	COG4499	WXG100 protein secretion system (Wss), protein YukC
MUY22_46205	COG0745	RESPONSE REGULATOR receiver
MUY22_46210	COG2205	protein histidine kinase activity
MUY22_46245	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_46250	COG4221	oxidoreductase activity
MUY22_46260	COG0514	ATP-dependent DNA helicase (RecQ)
MUY22_46270	COG0640	Transcriptional regulator
MUY22_46280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MUY22_46290	COG0542	response to heat
MUY22_46295	COG0667	Aldo Keto reductase
MUY22_46300	COG1309	transcriptional regulator
MUY22_46320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUY22_46320	COG2010	Cytochrome c
MUY22_46335	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
MUY22_46345	COG1940	carbohydrate kinase activity
MUY22_46345	COG1846	Transcriptional regulator
MUY22_46380	COG0248	Ppx GppA phosphatase
MUY22_46390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_46395	COG1295	ribonuclease BN
MUY22_46420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MUY22_46435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MUY22_46450	COG0640	Transcriptional regulator
MUY22_46455	COG0768	penicillin binding
MUY22_46460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MUY22_46480	COG3599	regulation of cell shape
MUY22_46490	COG1799	cell septum assembly
MUY22_46495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MUY22_46500	COG1496	oxidoreductase activity
MUY22_46505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MUY22_46515	COG1595	DNA-templated transcription, initiation
MUY22_46530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MUY22_46545	COG1846	Transcriptional regulator
MUY22_46560	COG2814	Major facilitator Superfamily
MUY22_46570	COG0702	epimerase
MUY22_46575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MUY22_46580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MUY22_46585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUY22_46595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUY22_46600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUY22_46615	COG0768	penicillin binding
MUY22_46625	COG0275	rRNA processing
MUY22_46630	COG2001	Belongs to the MraZ family
MUY22_46655	COG0714	Associated with various cellular activities
MUY22_46665	COG1305	Transglutaminase-like
MUY22_46675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUY22_46685	COG1192	Involved in chromosome partitioning
MUY22_46690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUY22_46700	COG0167	dihydroorotate dehydrogenase activity
MUY22_46715	COG1842	Phage shock protein A
MUY22_46720	COG1396	sequence-specific DNA binding
MUY22_46725	COG1058	Belongs to the CinA family
MUY22_46725	COG1546	Belongs to the CinA family
MUY22_46735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUY22_46740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MUY22_46760	COG1674	ftsk spoiiie
MUY22_46770	COG0655	NAD(P)H dehydrogenase (quinone) activity
MUY22_46785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MUY22_46790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUY22_46795	COG0515	serine threonine protein kinase
MUY22_46845	COG3214	Protein conserved in bacteria
MUY22_46870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MUY22_46880	COG1185	polyribonucleotide nucleotidyltransferase activity
MUY22_46885	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MUY22_46905	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MUY22_46910	COG2153	protein acetylation
MUY22_46925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MUY22_46940	COG0765	amino acid transport
MUY22_46945	COG1126	abc transporter atp-binding protein
MUY22_46950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUY22_46955	COG2268	Band 7 protein
MUY22_46970	COG2226	methyltransferase
MUY22_46990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MUY22_47015	COG0779	Required for maturation of 30S ribosomal subunits
MUY22_47055	COG4585	Histidine kinase
MUY22_47060	COG2197	response regulator
MUY22_47070	COG1733	regulation of RNA biosynthetic process
MUY22_47085	COG1309	transcriptional regulator
MUY22_47090	COG2936	dipeptidyl-peptidase activity
MUY22_47105	COG0745	RESPONSE REGULATOR receiver
MUY22_47110	COG5002	protein histidine kinase activity
MUY22_47150	COG0583	DNA-binding transcription factor activity
MUY22_47155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUY22_47160	COG1024	Enoyl-CoA hydratase
MUY22_47170	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUY22_47175	COG1960	acyl-CoA dehydrogenase activity
MUY22_47180	COG1316	TRANSCRIPTIONal
MUY22_47220	COG0583	DNA-binding transcription factor activity
MUY22_47300	COG0596	Alpha beta hydrolase
MUY22_47315	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUY22_47375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MUY22_47390	COG0667	Aldo Keto reductase
MUY22_47395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUY22_47405	COG1595	DNA-templated transcription, initiation
MUY22_47420	COG3321	synthase
MUY22_47420	COG0604	alcohol dehydrogenase
MUY22_47425	COG4335	DNA alkylation repair
MUY22_47445	COG2197	response regulator
MUY22_47460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUY22_47500	COG0583	DNA-binding transcription factor activity
MUY22_47550	COG1609	Transcriptional regulator
MUY22_47580	COG1132	(ABC) transporter
MUY22_47630	COG0069	glutamate synthase activity
MUY22_47635	COG0028	Belongs to the TPP enzyme family
MUY22_47655	COG0667	Aldo Keto reductase
MUY22_47660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUY22_47725	COG4106	trans-aconitate 2-methyltransferase activity
MUY22_47740	COG1595	DNA-templated transcription, initiation
MUY22_47775	COG2318	DinB family
MUY22_47795	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MUY22_47805	COG2197	response regulator
MUY22_47810	COG4585	Histidine kinase
MUY22_47820	COG1131	(ABC) transporter
MUY22_47825	COG0423	glycine-tRNA ligase activity
MUY22_47860	COG0701	Predicted permease
MUY22_47870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MUY22_47875	COG1381	Involved in DNA repair and RecF pathway recombination
MUY22_47905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MUY22_47920	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MUY22_47930	COG0537	adenosine 5'-monophosphoramidase activity
MUY22_47940	COG0484	heat shock protein binding
MUY22_47945	COG1420	regulation of RNA biosynthetic process
MUY22_47970	COG0667	Aldo Keto reductase
MUY22_47995	COG2205	protein histidine kinase activity
MUY22_48000	COG0745	RESPONSE REGULATOR receiver
MUY22_48005	COG1953	Uracil, thiamine, allantoin
MUY22_48015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUY22_48120	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MUY22_48125	COG2732	(Barnase) inhibitor
MUY22_48140	COG0604	alcohol dehydrogenase
MUY22_48150	COG0531	amino acid
MUY22_48155	COG2070	2-Nitropropane dioxygenase
MUY22_48200	COG2226	methyltransferase
MUY22_48215	COG0268	Binds directly to 16S ribosomal RNA
MUY22_48225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUY22_48230	COG0658	competence protein
MUY22_48230	COG2333	competence protein COMEC
MUY22_48240	COG1307	EDD domain protein, DegV family
MUY22_48250	COG0406	alpha-ribazole phosphatase activity
MUY22_48255	COG0799	negative regulation of ribosome biogenesis
MUY22_48260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MUY22_48275	COG0477	Major facilitator Superfamily
MUY22_48280	COG0018	arginyl-trna synthetase
MUY22_48295	COG3903	Transcriptional regulator
MUY22_48295	COG3629	intracellular signal transduction
MUY22_48305	COG0318	PFAM AMP-dependent synthetase and ligase
MUY22_48315	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MUY22_48320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MUY22_48325	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MUY22_48330	COG1530	ribonuclease E activity
MUY22_48365	COG0105	UTP biosynthetic process
MUY22_48375	COG2366	antibiotic biosynthetic process
MUY22_48385	COG0285	dihydrofolate synthase activity
MUY22_48400	COG2267	carboxylic ester hydrolase activity
MUY22_48405	COG0596	Alpha beta hydrolase
MUY22_48410	COG0583	DNA-binding transcription factor activity
MUY22_48420	COG0525	valine-tRNA ligase activity
MUY22_48440	COG0477	Major facilitator Superfamily
MUY22_48455	COG1316	TRANSCRIPTIONal
MUY22_48475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MUY22_48505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MUY22_48510	COG0740	serine-type endopeptidase activity
MUY22_48515	COG0740	serine-type endopeptidase activity
MUY22_48520	COG0544	peptidyl-prolyl cis-trans isomerase activity
MUY22_48530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUY22_48540	COG2205	protein histidine kinase activity
MUY22_48545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MUY22_48580	COG0717	Belongs to the dCTP deaminase family
MUY22_48610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MUY22_48640	COG1309	transcriptional regulator
MUY22_48650	COG3537	Alpha-1,2-mannosidase
MUY22_48655	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MUY22_48660	COG3559	Exporter of polyketide antibiotics
MUY22_48665	COG1131	(ABC) transporter
MUY22_48670	COG1309	transcriptional regulator
MUY22_48685	COG1846	Transcriptional regulator
MUY22_48685	COG1940	carbohydrate kinase activity
MUY22_48695	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_48740	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MUY22_48755	COG1879	ABC-type sugar transport system periplasmic component
MUY22_48760	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUY22_48765	COG1129	ABC transporter
MUY22_48780	COG2814	Major facilitator Superfamily
MUY22_48785	COG0656	L-ascorbic acid biosynthetic process
MUY22_48815	COG0693	protein deglycase activity
MUY22_48825	COG5002	protein histidine kinase activity
MUY22_48825	COG0784	Response regulator, receiver
MUY22_48860	COG1733	regulation of RNA biosynthetic process
MUY22_48880	COG0504	CTP synthase activity
MUY22_48890	COG0698	ribose 5-phosphate isomerase
MUY22_48905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MUY22_48915	COG2826	transposase and inactivated derivatives, IS30 family
MUY22_48920	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MUY22_48940	COG0668	transmembrane transport
MUY22_48950	COG0366	Alpha amylase catalytic
MUY22_48970	COG2902	Dehydrogenase
MUY22_48985	COG3336	cytochrome c oxidase
MUY22_49000	COG0738	Major facilitator superfamily
MUY22_49025	COG1960	acyl-CoA dehydrogenase activity
MUY22_49035	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MUY22_49050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_49070	COG2124	cytochrome p450
MUY22_49140	COG4977	sequence-specific DNA binding
MUY22_49140	COG1917	Cupin 2, conserved barrel domain protein
MUY22_49155	COG4941	Belongs to the sigma-70 factor family
MUY22_49170	COG0009	L-threonylcarbamoyladenylate synthase
MUY22_49185	COG2197	response regulator
MUY22_49195	COG1917	Cupin 2, conserved barrel domain protein
MUY22_49195	COG4977	sequence-specific DNA binding
MUY22_49200	COG2197	response regulator
MUY22_49205	COG4585	Histidine kinase
MUY22_49245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MUY22_49260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MUY22_49265	COG0243	molybdopterin cofactor binding
MUY22_49285	COG0477	Major facilitator Superfamily
MUY22_49330	COG1960	acyl-CoA dehydrogenase activity
MUY22_49345	COG0277	FAD linked oxidase domain protein
MUY22_49350	COG1028	Short-chain dehydrogenase reductase Sdr
MUY22_49365	COG1285	pathogenesis
MUY22_49385	COG1937	Protein conserved in bacteria