locus-tag	class	description
Anacy_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Anacy_0002	ENOG4105KPY	Small multidrug resistance protein
Anacy_0004	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
Anacy_0011	ENOG4105K64	Glycosyl transferase, family 2
Anacy_0012	ENOG4105CJ1	ABC, transporter
Anacy_0016	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Anacy_0020	ENOG4105CGK	Exodeoxyribonuclease III
Anacy_0024	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Anacy_0027	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Anacy_0029	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Anacy_0031	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
Anacy_0042	ENOG4105DIK	(ABC) transporter
Anacy_0043	ENOG4105CC5	ABC transporter
Anacy_0046	ENOG4105CHH	sulfate transporter
Anacy_0048	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Anacy_0049	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Anacy_0053	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
Anacy_0059	ENOG4105CUT	histidyl-tRNA synthetase
Anacy_0065	ENOG4107Z6A	sulfate abc transporter permease
Anacy_0066	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Anacy_0067	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Anacy_0069	ENOG4105E7A	Glutamine amidotransferase
Anacy_0070	ENOG4105E0X	reductase
Anacy_0078	ENOG4105WCA	Ferredoxin
Anacy_0089	ENOG4105ND9	Nitrogenase-associated protein
Anacy_0095	ENOG4106KE4	Dehydrogenase
Anacy_0098	ENOG4105CK2	sodium dicarboxylate symporter
Anacy_0099	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Anacy_0101	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Anacy_0102	ENOG4105KD7	acetyltransferase
Anacy_0104	ENOG4105D05	Receptor
Anacy_0109	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
Anacy_0114	ENOG4105C59	p-type ATPase
Anacy_0119	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Anacy_0121	ENOG4105D7Z	glutathione synthase
Anacy_0122	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Anacy_0125	ENOG4105CPJ	photosystem II manganese-stabilizing
Anacy_0126	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anacy_0132	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Anacy_0139	ENOG4107RAQ	aminopeptidase
Anacy_0140	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
Anacy_0146	ENOG4105C1V	Peptidase, M16
Anacy_0162	ENOG4105CSV	Glutaminase
Anacy_0163	ENOG4105K6T	rare lipoprotein A
Anacy_0164	ENOG4105CAT	Cytidine monophosphate kinase
Anacy_0165	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Anacy_0182	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anacy_0187	ENOG4105BZU	Histidine kinase
Anacy_0210	ENOG4105CFG	Acts as a chaperone (By similarity)
Anacy_0211	ENOG4105E5J	UV damage endonuclease
Anacy_0214	ENOG4105D7W	serine acetyltransferase
Anacy_0218	ENOG4107S73	homocitrate synthase
Anacy_0224	ENOG4105K63	Thioredoxin
Anacy_0229	ENOG4105WEF	catalase
Anacy_0230	ENOG4105Y3U	Transglycosylase-associated protein
Anacy_0233	ENOG4105BZU	Histidine kinase
Anacy_0234	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anacy_0236	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_0238	ENOG41066AK	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
Anacy_0243	ENOG4105C9B	Cysteine desulfurase
Anacy_0246	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Anacy_0248	ENOG4105VT3	DNA binding domain protein, excisionase family
Anacy_0250	ENOG4105CPQ	Dehydrogenase
Anacy_0251	ENOG4105CJ3	phosphate transporter
Anacy_0253	ENOG4108K9Q	Controls heterocyst differentiation. Has both a protease and a DNA-binding activity (By similarity)
Anacy_0255	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Anacy_0256	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Anacy_0257	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Anacy_0258	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Anacy_0260	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Anacy_0261	ENOG4105D4A	Cell wall formation (By similarity)
Anacy_0262	ENOG4105DFU	Cell wall formation (By similarity)
Anacy_0264	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Anacy_0265	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Anacy_0266	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Anacy_0271	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Anacy_0272	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Anacy_0275	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
Anacy_0278	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anacy_0281	ENOG4105BZ1	(ABC) transporter
Anacy_0284	ENOG4107YJ4	chain length determinant protein
Anacy_0285	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anacy_0287	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Anacy_0289	ENOG4107XZA	Glycosyl transferase family 2
Anacy_0292	ENOG4107XZA	Glycosyl transferase family 2
Anacy_0294	ENOG4105CMR	udp-glucose 4-epimerase
Anacy_0295	ENOG4105D5U	fad dependent oxidoreductase
Anacy_0296	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
Anacy_0299	ENOG4108M24	von Willebrand factor, type A
Anacy_0301	ENOG4108IJ9	(ABC) transporter
Anacy_0302	ENOG4105DX0	Hemolysin A
Anacy_0304	ENOG4105CNF	WD-40 repeat protein
Anacy_0305	ENOG4108TCG	allophycocyanin beta subunit
Anacy_0308	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Anacy_0311	ENOG4105CPK	Glycosyl transferase (Group 1
Anacy_0315	ENOG4108MJN	Glycosyl Transferase
Anacy_0316	ENOG4105Q84	sucrose synthase
Anacy_0318	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Anacy_0325	ENOG4108JQC	penicillin-binding protein 1A
Anacy_0327	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_0330	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
Anacy_0333	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Anacy_0339	ENOG4108PJD	permease
Anacy_0348	ENOG4105CHR	reductase
Anacy_0349	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Anacy_0350	ENOG4108UW5	maltose o-acetyltransferase
Anacy_0352	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Anacy_0355	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Anacy_0356	ENOG4105ETX	regulatoR
Anacy_0370	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anacy_0371	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Anacy_0372	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anacy_0373	ENOG4108IV0	ABC, transporter
Anacy_0379	ENOG4105GFR	rna polymerase sigma factor
Anacy_0387	ENOG4105CBS	Chea signal transduction histidine kinase
Anacy_0388	ENOG4108NVR	Methyl-accepting chemotaxis
Anacy_0393	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Anacy_0396	ENOG4105CRE	cytochrome C
Anacy_0400	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Anacy_0402	ENOG4106AG1	Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity)
Anacy_0406	ENOG4105E33	succinate dehydrogenase
Anacy_0409	ENOG4105C3M	thioredoxin reductase
Anacy_0412	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Anacy_0413	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Anacy_0414	ENOG4107QX9	Thiol disulfide interChange protein
Anacy_0422	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Anacy_0426	ENOG4108ZF3	Phosphatase
Anacy_0430	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
Anacy_0432	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Anacy_0434	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Anacy_0435	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
Anacy_0437	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anacy_0438	ENOG4108U7W	acetyltransferase
Anacy_0445	ENOG4105NP4	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
Anacy_0446	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
Anacy_0450	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anacy_0461	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Anacy_0462	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Anacy_0469	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Anacy_0479	ENOG4105DUM	transcriptional regulator, lysR family
Anacy_0482	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
Anacy_0483	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Anacy_0484	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
Anacy_0486	ENOG4105D65	subunit l
Anacy_0487	ENOG4105C8S	subunit m
Anacy_0492	ENOG4108JJA	ABC, transporter
Anacy_0501	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Anacy_0503	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Anacy_0509	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Anacy_0510	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anacy_0511	ENOG4107YX3	NADH dehydrogenase subunit j
Anacy_0512	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anacy_0513	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Anacy_0516	ENOG4105BZU	Histidine kinase
Anacy_0517	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_0518	ENOG41089UC	methyltransferase, type 11
Anacy_0520	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Anacy_0522	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Anacy_0523	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Anacy_0526	ENOG41087PP	glycosyltransferase MGT family
Anacy_0529	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
Anacy_0531	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Anacy_0532	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Anacy_0534	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Anacy_0537	ENOG4105D52	delta-aminolevulinic acid dehydratase
Anacy_0542	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Anacy_0546	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anacy_0548	ENOG4105F23	Fibronectin-binding protein
Anacy_0556	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Anacy_0557	ENOG4108VV8	photosystem i
Anacy_0559	ENOG4108W6I	photosystem I reaction center protein subunit XI
Anacy_0560	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Anacy_0561	ENOG4105KC4	UPF0296 protein
Anacy_0568	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Anacy_0569	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Anacy_0570	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
Anacy_0573	ENOG41080E3	single-stranded DNA-binding protein
Anacy_0574	ENOG4105DFF	Rod shape-determining protein mreb
Anacy_0582	ENOG4107XZC	Restriction modification system DNA (Specificity
Anacy_0585	ENOG4105CVR	type I restriction-modification system
Anacy_0587	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
Anacy_0592	ENOG4108HMN	Caspase domain
Anacy_0596	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
Anacy_0598	ENOG4105CVR	type I restriction-modification system
Anacy_0604	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Anacy_0605	ENOG4105E0Y	RtcB Protein
Anacy_0607	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Anacy_0617	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Anacy_0618	ENOG41082AN	stage II sporulation protein
Anacy_0633	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Anacy_0638	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anacy_0639	ENOG4105CXN	decarboxylase
Anacy_0640	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Anacy_0642	ENOG4105BZU	Histidine kinase
Anacy_0643	ENOG4108VYJ	response regulator receiver protein
Anacy_0645	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Anacy_0646	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Anacy_0651	ENOG4105F4R	Transcriptional regulator mode
Anacy_0657	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Anacy_0660	ENOG4108IQE	Amp-dependent synthetase and ligase
Anacy_0663	ENOG4105C7S	Dehydrogenase
Anacy_0666	ENOG4105VGQ	Photosystem I subunit X
Anacy_0674	ENOG4105YAJ	CopG Arc MetJ
Anacy_0682	ENOG4105CTK	cobaltochelatase, cobn subunit
Anacy_0691	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Anacy_0692	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Anacy_0699	ENOG4107TCE	N-acetyltransferase
Anacy_0701	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Anacy_0704	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
Anacy_0705	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Anacy_0713	ENOG4105CFP	Peptidase U32
Anacy_0717	ENOG4105CIK	Amidinotransferase
Anacy_0722	ENOG4105D5K	Hemolysin activator protein
Anacy_0741	ENOG4105BZU	Histidine kinase
Anacy_0755	ENOG4107R7Y	intracellular protease Pfpi family
Anacy_0759	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
Anacy_0760	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
Anacy_0763	ENOG4107SCA	Formamidase (EC 3.5.1.49)
Anacy_0764	ENOG41080HI	glycine oxidase
Anacy_0766	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
Anacy_0767	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
Anacy_0772	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Anacy_0773	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Anacy_0779	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Anacy_0782	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Anacy_0783	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Anacy_0787	ENOG4105CHH	sulfate transporter
Anacy_0789	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Anacy_0802	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Anacy_0806	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
Anacy_0809	ENOG4105BZU	Histidine kinase
Anacy_0811	ENOG4107Z8V	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Anacy_0814	ENOG4105D9P	serine threonine protein kinase
Anacy_0817	ENOG4105D7N	magnesium and cobalt transport protein CorA
Anacy_0819	ENOG4105CD3	dihydroorotase
Anacy_0820	ENOG4105K8N	protein family UPF0079, ATPase
Anacy_0821	ENOG4105CHW	UPF0052 protein
Anacy_0822	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Anacy_0826	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Anacy_0827	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Anacy_0838	ENOG4108TNP	
Anacy_0840	ENOG4105D7K	pfkb domain protein
Anacy_0843	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
Anacy_0844	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Anacy_0849	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Anacy_0850	ENOG4105CVJ	phosphoglycerate mutase
Anacy_0853	ENOG4107XM9	(LipO)protein
Anacy_0857	ENOG4108SHN	Glycosyl transferase, family 2
Anacy_0859	ENOG41083EU	50s ribosomal protein l28
Anacy_0869	ENOG4106WTF	Glycosyl transferase, family 2
Anacy_0871	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
Anacy_0873	ENOG4107SGM	protein serine threonine phosphatase
Anacy_0880	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Anacy_0887	ENOG41067HS	methyltransferase
Anacy_0892	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anacy_0898	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Anacy_0901	ENOG4108JQ6	ABC transporter
Anacy_0907	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Anacy_0914	ENOG4105VPX	protein, conserved in bacteria
Anacy_0915	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
Anacy_0924	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Anacy_0936	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Anacy_0938	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Anacy_0943	ENOG4105CPC	Aldo Keto reductase
Anacy_0949	ENOG4105NI8	Cytosine-specific methyltransferase
Anacy_0951	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Anacy_0957	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Anacy_0961	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Anacy_0973	ENOG4108JJB	ABC transporter
Anacy_0974	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Anacy_0983	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Anacy_0985	ENOG4105BZU	Histidine kinase
Anacy_0986	ENOG4108IJ9	(ABC) transporter
Anacy_0989	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Anacy_0991	ENOG4105QYV	Membrane
Anacy_0992	ENOG41090HT	Inherit from COG: transposase
Anacy_0993	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Anacy_0996	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Anacy_1003	ENOG4107QRI	Phosphoketolase
Anacy_1004	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Anacy_1008	ENOG4105D7W	serine acetyltransferase
Anacy_1021	ENOG4105X25	
Anacy_1022	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Anacy_1023	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Anacy_1024	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Anacy_1025	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
Anacy_1026	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Anacy_1030	ENOG4105DJZ	UPF0182 protein
Anacy_1038	ENOG41065W4	chlorophyll a b binding light harvesting protein
Anacy_1039	ENOG4108JH3	
Anacy_1040	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
Anacy_1042	ENOG4105E9X	Photosystem II 44 kDa subunit reaction center protein
Anacy_1047	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Anacy_1056	ENOG4105CBS	Chea signal transduction histidine kinase
Anacy_1061	ENOG4108HHA	Transketolase
Anacy_1065	ENOG4105D0S	secretion protein (HlyD
Anacy_1066	ENOG4105U3E	Transcriptional regulator
Anacy_1067	ENOG4105T2N	Domain of unknown function (DUF2382)
Anacy_1068	ENOG4105T2N	Domain of unknown function (DUF2382)
Anacy_1074	ENOG4108JYK	Dehydrogenase
Anacy_1076	ENOG4105C75	arginyL-tRNA synthetase
Anacy_1086	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_1087	ENOG4105GR3	Histidine kinase
Anacy_1089	ENOG4108QF0	This is one of the two reaction center proteins of photosystem II
Anacy_1090	ENOG4108UDB	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
Anacy_1094	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Anacy_1108	ENOG4105DKQ	ROK family
Anacy_1111	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Anacy_1117	ENOG4105C12	Phosphoribosylglycinamide synthetase
Anacy_1118	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Anacy_1124	ENOG4105BZU	Histidine kinase
Anacy_1126	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
Anacy_1129	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Anacy_1130	ENOG4108RVA	ribokinase
Anacy_1131	ENOG41067D0	Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of toxin RelE2
Anacy_1133	ENOG4108Z6B	deaminase
Anacy_1136	ENOG4105DTQ	mandelate racemase muconate lactonizing
Anacy_1149	ENOG4105E39	Enoyl-CoA hydratase
Anacy_1150	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Anacy_1152	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Anacy_1153	ENOG4105WH1	Two component transcriptional regulator luxr family
Anacy_1154	ENOG4105D9P	serine threonine protein kinase
Anacy_1176	ENOG4105C0D	helicase
Anacy_1177	ENOG4105QMX	Protein of unknown function (DUF1186)
Anacy_1178	ENOG4105VXP	Protein of unknown function DUF86
Anacy_1183	ENOG4108KU9	integrase family
Anacy_1194	ENOG4107QXX	ABC transporter
Anacy_1200	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Anacy_1209	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anacy_1211	ENOG4108I5C	dEAD DEAH box helicase
Anacy_1218	ENOG4105C6E	dna polymerase iii
Anacy_1234	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Anacy_1235	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anacy_1240	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
Anacy_1241	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
Anacy_1246	ENOG4107TSN	permease
Anacy_1247	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Anacy_1257	ENOG4108IYU	L-aspartate oxidase
Anacy_1261	ENOG4105CPC	Aldo Keto reductase
Anacy_1262	ENOG4108PWY	Carbohydrate-selective porin OprB
Anacy_1264	ENOG4105E2Y	ABC, transporter
Anacy_1266	ENOG4105GVF	(ABC) transporter
Anacy_1267	ENOG4105E2B	Taurine dioxygenase
Anacy_1268	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Anacy_1269	ENOG4105GVF	(ABC) transporter
Anacy_1270	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Anacy_1271	ENOG4105FBW	Monooxygenase
Anacy_1272	ENOG4108UZX	fmn reductase
Anacy_1275	ENOG4105BZU	Histidine kinase
Anacy_1276	ENOG4108302	MgtC SapB transporter
Anacy_1277	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Anacy_1279	ENOG4105EMU	Dehydrogenase
Anacy_1283	ENOG4105CNF	WD-40 repeat protein
Anacy_1289	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Anacy_1305	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Anacy_1312	ENOG4107MKT	Stringent starvation protein a
Anacy_1322	ENOG4105CPU	Monooxygenase
Anacy_1323	ENOG4105CPU	Monooxygenase
Anacy_1326	ENOG4105CPC	Aldo Keto reductase
Anacy_1327	ENOG4105GVF	(ABC) transporter
Anacy_1328	ENOG4105BZ1	(ABC) transporter
Anacy_1360	ENOG4105CP2	von willebrand factor, type a
Anacy_1363	ENOG4105C0D	helicase
Anacy_1366	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Anacy_1370	ENOG4105C31	Tryptophanyl-tRNA synthetase
Anacy_1385	ENOG41063C6	UPF0235 protein
Anacy_1407	ENOG4105CC5	ABC transporter
Anacy_1408	ENOG4107YCR	Transcriptional regulator, ARSR family
Anacy_1409	ENOG4105FDK	ABC transporter
Anacy_1410	ENOG4105DSE	periplasmic solute binding protein
Anacy_1411	ENOG4108PWY	Carbohydrate-selective porin OprB
Anacy_1412	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Anacy_1413	ENOG4105BZU	Histidine kinase
Anacy_1414	ENOG4107WJM	-acetyltransferase
Anacy_1417	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Anacy_1427	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Anacy_1433	ENOG4108R99	pseudouridine synthase
Anacy_1435	ENOG4107WDG	serine threonine protein kinase
Anacy_1440	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Anacy_1443	ENOG4105CMR	udp-glucose 4-epimerase
Anacy_1447	ENOG4105D9R	oxidoreductase
Anacy_1448	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Anacy_1450	ENOG4106855	Competence protein
Anacy_1451	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Anacy_1452	ENOG4105C3M	thioredoxin reductase
Anacy_1453	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Anacy_1455	ENOG4105DKQ	ROK family
Anacy_1457	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Anacy_1458	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Anacy_1459	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Anacy_1463	ENOG4105C4W	S-formylglutathione hydrolase
Anacy_1466	ENOG4107QPD	alcohol dehydrogenase
Anacy_1467	ENOG4105JKW	Valine--pyruvate aminotransferase
Anacy_1468	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Anacy_1473	ENOG4105CHC	glucokinase (EC 2.7.1.2)
Anacy_1482	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
Anacy_1489	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Anacy_1490	ENOG4107RNU	major facilitator superfamily MFS_1
Anacy_1492	ENOG4105I5W	Transporter
Anacy_1500	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Anacy_1505	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Anacy_1512	ENOG4105DFS	Conserved Protein
Anacy_1518	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Anacy_1519	ENOG4105F0N	pyrophosphate phospho-hydrolase
Anacy_1525	ENOG4108IJ0	Aspartate ammonia-lyase
Anacy_1526	ENOG4105DZP	Membrane-associated zinc metalloprotease
Anacy_1529	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Anacy_1531	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Anacy_1534	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Anacy_1538	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Anacy_1541	ENOG4105CN1	protease
Anacy_1544	ENOG4105WQ3	Rna-binding protein
Anacy_1545	ENOG4108IPT	Naphthoate synthase
Anacy_1551	ENOG4105N6Y	Thioredoxin
Anacy_1552	ENOG4105CHM	Aminotransferase
Anacy_1554	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Anacy_1557	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Anacy_1559	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Anacy_1560	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Anacy_1561	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Anacy_1569	ENOG41083UI	stage II sporulation protein
Anacy_1573	ENOG4105C02	permease
Anacy_1574	ENOG4105C8N	cysteinyl-tRNA synthetase
Anacy_1576	ENOG4105CKI	cobalamin synthesis protein
Anacy_1577	ENOG4105G6Z	alkaline phosphatase
Anacy_1578	ENOG4105MSA	Photosystem II reaction center W protein
Anacy_1579	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
Anacy_1581	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
Anacy_1582	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Anacy_1585	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
Anacy_1586	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Anacy_1588	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
Anacy_1590	ENOG4105DRS	transport system, permease
Anacy_1591	ENOG4105D3Q	Sugar transferase
Anacy_1594	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Anacy_1596	ENOG4108K7V	UPF0284 protein
Anacy_1600	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Anacy_1603	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Anacy_1605	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Anacy_1606	ENOG4105D3Q	Sugar transferase
Anacy_1607	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anacy_1608	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
Anacy_1611	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Anacy_1614	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
Anacy_1620	ENOG4105BZU	Histidine kinase
Anacy_1621	ENOG4105BZU	Histidine kinase
Anacy_1622	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anacy_1626	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Anacy_1630	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_1631	ENOG4105EB3	Histidine kinase
Anacy_1633	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
Anacy_1635	ENOG4108PWY	Carbohydrate-selective porin OprB
Anacy_1636	ENOG4108PWY	Carbohydrate-selective porin OprB
Anacy_1638	ENOG4108SHJ	s-layer protein
Anacy_1639	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
Anacy_1643	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Anacy_1649	ENOG4105BZU	Histidine kinase
Anacy_1650	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
Anacy_1651	ENOG4105CNW	domain protein
Anacy_1652	ENOG4105CNW	domain protein
Anacy_1659	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Anacy_1661	ENOG4105BZU	Histidine kinase
Anacy_1662	ENOG4105BZU	Histidine kinase
Anacy_1666	ENOG4108KGH	TRANSCRIPTIONal
Anacy_1676	ENOG41080XM	UPF0145 protein
Anacy_1685	ENOG4105CKI	cobalamin synthesis protein
Anacy_1688	ENOG4105DSE	periplasmic solute binding protein
Anacy_1689	ENOG4105JZI	cytochrome P450
Anacy_1693	ENOG4105EWK	phytoene
Anacy_1695	ENOG4105JZI	cytochrome P450
Anacy_1696	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Anacy_1707	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Anacy_1710	ENOG4105EMU	Dehydrogenase
Anacy_1718	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Anacy_1723	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Anacy_1730	ENOG4105W5K	Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity)
Anacy_1733	ENOG4105EEK	Polypeptide
Anacy_1738	ENOG4107SWE	Methyltransferase
Anacy_1739	ENOG4105PA3	atp synthase
Anacy_1740	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
Anacy_1741	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Anacy_1742	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Anacy_1743	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Anacy_1744	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Anacy_1745	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Anacy_1746	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Anacy_1754	ENOG4107YFT	Nadph-dependent fmn reductase
Anacy_1755	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Anacy_1759	ENOG4107UWC	ABC, transporter
Anacy_1775	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
Anacy_1777	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
Anacy_1800	ENOG4105C8H	hydrogenase maturation protein Hypf
Anacy_1802	ENOG4105CQS	hydrogenase expression formation protein HypD
Anacy_1804	ENOG4105C45	hydrogenase expression formation protein (HypE)
Anacy_1805	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
Anacy_1806	ENOG4107RSS	Hydrogenase accessory protein HypB
Anacy_1808	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Anacy_1810	ENOG4108DJF	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Anacy_1812	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Anacy_1813	ENOG4105E4C	Lytic transglycosylase catalytic
Anacy_1814	ENOG4108R6K	riboflavin synthase, subunit alpha
Anacy_1816	ENOG4105CV8	reductase
Anacy_1817	ENOG4107RNB	anthranilate phosphoribosyltransferase
Anacy_1819	ENOG4105K46	50S ribosomal protein l27
Anacy_1820	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Anacy_1822	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
Anacy_1834	ENOG4105XEV	csbD-like
Anacy_1837	ENOG4108VIA	integral membrane protein
Anacy_1839	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Anacy_1842	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
Anacy_1846	ENOG4105DA5	(ABC) transporter
Anacy_1847	ENOG4105D64	Mechanosensitive ion channel
Anacy_1848	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Anacy_1851	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Anacy_1860	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Anacy_1862	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
Anacy_1863	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
Anacy_1864	ENOG4105TQG	cytochrome C, class I
Anacy_1869	ENOG4105BZU	Histidine kinase
Anacy_1872	ENOG4108UXN	response regulator
Anacy_1873	ENOG4105BZU	Histidine kinase
Anacy_1874	ENOG4105BZU	Histidine kinase
Anacy_1875	ENOG4105WH1	Two component transcriptional regulator luxr family
Anacy_1886	ENOG4107STW	synthase
Anacy_1896	ENOG4105D6V	phycocyanin beta subunit
Anacy_1897	ENOG4108SDR	phycocyanin, alpha subunit
Anacy_1898	ENOG4108MZQ	phycobilisome linker polypeptide
Anacy_1900	ENOG41078GB	pbs lyase
Anacy_1901	ENOG4108V9J	phycocyanobilin lyase
Anacy_1902	ENOG4106BTU	phycobilisome rod-core linker polypeptide
Anacy_1903	ENOG4106BTU	phycobilisome rod-core linker polypeptide
Anacy_1904	ENOG4106Q05	Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes (By similarity)
Anacy_1907	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Anacy_1910	ENOG4105CAQ	asparagine synthetase
Anacy_1913	ENOG4107RRY	Cyanophycin synthetase
Anacy_1917	ENOG4105C72	UPF0176 protein
Anacy_1919	ENOG4105DBI	uridine monophosphokinase
Anacy_1920	ENOG4108UV1	cellular component movement
Anacy_1924	ENOG4105CA3	membrane-bound lytic murein transglycosylase
Anacy_1926	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Anacy_1929	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
Anacy_1932	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
Anacy_1933	ENOG4105CMR	udp-glucose 4-epimerase
Anacy_1934	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Anacy_1936	ENOG4105D5D	udp-galactopyranose mutase
Anacy_1940	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Anacy_1944	ENOG4105C26	Dehydrogenase
Anacy_1950	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anacy_1951	ENOG4105BZU	Histidine kinase
Anacy_1960	ENOG4108JJA	ABC, transporter
Anacy_1965	ENOG4108JJA	ABC, transporter
Anacy_1967	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Anacy_1971	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Anacy_1972	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anacy_1973	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Anacy_1974	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Anacy_1980	ENOG410828V	rubredoxin
Anacy_1981	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
Anacy_1982	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
Anacy_1983	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
Anacy_1984	ENOG4106DN3	This protein is a component of the reaction center of photosystem II (By similarity)
Anacy_1993	ENOG4108I6A	alcohol dehydrogenase
Anacy_2001	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Anacy_2003	ENOG4105DR5	peptidase
Anacy_2006	ENOG4105PDP	Short chain dehydrogenase
Anacy_2007	ENOG4105Y7M	Transcriptional regulator, TetR family
Anacy_2013	ENOG4105KVH	Transcriptional regulator
Anacy_2014	ENOG4105ECR	NmrA family
Anacy_2017	ENOG4107QI6	Cysteine desulfurase
Anacy_2035	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Anacy_2041	ENOG4105E4C	Lytic transglycosylase catalytic
Anacy_2045	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Anacy_2053	ENOG4107QZB	decarboxylase
Anacy_2054	ENOG4105K70	DNA-binding protein
Anacy_2058	ENOG4105GVR	general secretion pathway protein D
Anacy_2063	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Anacy_2065	ENOG4108UW5	maltose o-acetyltransferase
Anacy_2075	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
Anacy_2077	ENOG4105F32	YngK protein
Anacy_2079	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Anacy_2081	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Anacy_2082	ENOG4105CEP	NADH dehydrogenase
Anacy_2086	ENOG4105CQB	FAD linked oxidase domain protein
Anacy_2087	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Anacy_2088	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Anacy_2102	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Anacy_2106	ENOG4105C3J	Cysteine desulfurase
Anacy_2107	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
Anacy_2145	ENOG4105E71	FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off
Anacy_2158	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
Anacy_2162	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
Anacy_2168	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
Anacy_2199	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Anacy_2200	ENOG4108S59	
Anacy_2216	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
Anacy_2218	ENOG4105D0B	Nitrogenase protein alpha chain
Anacy_2219	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
Anacy_2220	ENOG4108UR2	Nitrogen fixation protein NifX
Anacy_2221	ENOG4108VQE	nitrogen fixation protein
Anacy_2222	ENOG4105X87	nitrogen fixation
Anacy_2223	ENOG4105R88	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
Anacy_2224	ENOG41081QJ	UBA THIF-type NAD FAD binding
Anacy_2225	ENOG4105V5Z	Iron-sulfur cluster assembly accessory protein
Anacy_2232	ENOG4105EXC	Acyl-transferase
Anacy_2243	ENOG4105CPF	Cell wall formation (By similarity)
Anacy_2247	ENOG4107S2Z	UPF0761 membrane protein
Anacy_2258	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Anacy_2260	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Anacy_2262	ENOG4105BZU	Histidine kinase
Anacy_2269	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Anacy_2274	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Anacy_2275	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Anacy_2278	ENOG4105IIU	Aminopeptidase
Anacy_2281	ENOG4105CMR	udp-glucose 4-epimerase
Anacy_2283	ENOG4105BZ1	(ABC) transporter
Anacy_2284	ENOG4107SC1	transglycosylase
Anacy_2289	ENOG4105CDY	transcriptional regulatory protein
Anacy_2290	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Anacy_2291	ENOG41082B1	30S ribosomal protein S16
Anacy_2297	ENOG4105BZ1	(ABC) transporter
Anacy_2299	ENOG4106QP8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Anacy_2300	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Anacy_2302	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
Anacy_2303	ENOG4105Q36	FHA domain containing protein
Anacy_2307	ENOG4105C5I	Dehydrogenase
Anacy_2312	ENOG41083UI	stage II sporulation protein
Anacy_2319	ENOG4108PWY	Carbohydrate-selective porin OprB
Anacy_2322	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Anacy_2323	ENOG4105F8J	Adenylate Guanylate cyclase
Anacy_2328	ENOG4105DN3	alpha-2-macroglobulin domain protein
Anacy_2329	ENOG4108JQB	penicillin-binding protein 1C
Anacy_2337	ENOG4105CVN	desaturase
Anacy_2339	ENOG4107EFQ	arachidonate 15-lipoxygenase
Anacy_2341	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Anacy_2343	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Anacy_2350	ENOG4105EET	magnesium chelatase
Anacy_2352	ENOG4107TVC	Glycosyl transferase, family 2
Anacy_2363	ENOG4105D74	hydrolase
Anacy_2365	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Anacy_2367	ENOG4107SC0	ferredoxin--NADP reductase
Anacy_2369	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Anacy_2370	ENOG4105BZU	Histidine kinase
Anacy_2376	ENOG4105D9P	serine threonine protein kinase
Anacy_2380	ENOG4105CJ1	ABC, transporter
Anacy_2383	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Anacy_2384	ENOG4108KGH	TRANSCRIPTIONal
Anacy_2385	ENOG4105N7N	Pentapeptide repeat-containing protein
Anacy_2395	ENOG41086DT	Membrane protein of unknown function
Anacy_2397	ENOG4105BZM	domain protein
Anacy_2405	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
Anacy_2405	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
Anacy_2408	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Anacy_2413	ENOG410686T	photosystem II reaction center protein N
Anacy_2414	ENOG4105WIA	photosystem II reaction center protein H
Anacy_2415	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Anacy_2416	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Anacy_2417	ENOG410848W	30S ribosomal protein S21
Anacy_2419	ENOG4108QCI	YvbH-like oligomerisation region
Anacy_2422	ENOG4105BZU	Histidine kinase
Anacy_2423	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
Anacy_2440	ENOG4105C89	phosphohexose isomerase
Anacy_2441	ENOG4105BZU	Histidine kinase
Anacy_2444	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Anacy_2445	ENOG4105C0Z	ABC transporter
Anacy_2448	ENOG4108VCT	Sulfite exporter TauE/SafE
Anacy_2452	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Anacy_2453	ENOG4105CBT	Fructose-1,6-bisphosphatase
Anacy_2455	ENOG4108Z6B	deaminase
Anacy_2457	ENOG4108HMN	Caspase domain
Anacy_2460	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Anacy_2464	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Anacy_2465	ENOG4107SDT	Homocitrate synthase
Anacy_2467	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
Anacy_2468	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Anacy_2474	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anacy_2477	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Anacy_2482	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Anacy_2484	ENOG4105CQC	Prephenate dehydratase
Anacy_2485	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Anacy_2486	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Anacy_2487	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Anacy_2488	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Anacy_2489	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Anacy_2490	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Anacy_2492	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Anacy_2496	ENOG4108ZJ4	polysaccharide deacetylase
Anacy_2502	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Anacy_2510	ENOG4105D0M	Protease HtpX homolog
Anacy_2527	ENOG4105BZU	Histidine kinase
Anacy_2529	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anacy_2533	ENOG4105BZU	Histidine kinase
Anacy_2549	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Anacy_2553	ENOG4105CP7	Triose-phosphate isomerase
Anacy_2556	ENOG4107XWB	Zinc finger, swim domain protein
Anacy_2558	ENOG4105C0D	helicase
Anacy_2558	ENOG4105C0D	helicase
Anacy_2564	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Anacy_2571	ENOG4108R0D	protein with myosin-like
Anacy_2572	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
Anacy_2573	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Anacy_2574	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Anacy_2575	ENOG4105DA5	(ABC) transporter
Anacy_2576	ENOG4105DAY	polysaccharide export protein
Anacy_2578	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
Anacy_2579	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
Anacy_2581	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Anacy_2583	ENOG4105F8J	Adenylate Guanylate cyclase
Anacy_2584	ENOG4105CPQ	Dehydrogenase
Anacy_2588	ENOG4107WDG	serine threonine protein kinase
Anacy_2592	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Anacy_2593	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Anacy_2594	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Anacy_2596	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
Anacy_2597	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Anacy_2600	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Anacy_2604	ENOG4105EWK	phytoene
Anacy_2613	ENOG4107WDG	serine threonine protein kinase
Anacy_2614	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Anacy_2615	ENOG4107Z3D	50S ribosomal protein l10
Anacy_2616	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Anacy_2617	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Anacy_2620	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Anacy_2621	ENOG4105K64	Glycosyl transferase, family 2
Anacy_2622	ENOG4107T8Q	Glycosyl transferase (Group 1
Anacy_2623	ENOG4105BZS	acriflavin resistance protein
Anacy_2625	ENOG4108Y85	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
Anacy_2626	ENOG4105VFU	Rna-binding protein
Anacy_2629	ENOG41086VY	Fic/DOC family
Anacy_2632	ENOG4105CNW	domain protein
Anacy_2633	ENOG4105CNW	domain protein
Anacy_2634	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Anacy_2640	ENOG4105CH7	arginosuccinase
Anacy_2642	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Anacy_2646	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Anacy_2647	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Anacy_2648	ENOG4105DDG	Cyanophycinase
Anacy_2649	ENOG4107RRY	Cyanophycin synthetase
Anacy_2650	ENOG41063NY	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Anacy_2651	ENOG4107WDG	serine threonine protein kinase
Anacy_2653	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
Anacy_2662	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Anacy_2669	ENOG4105CQB	FAD linked oxidase domain protein
Anacy_2670	ENOG4105F32	YngK protein
Anacy_2676	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Anacy_2677	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Anacy_2689	ENOG4108NWW	ferritin dps family protein
Anacy_2690	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Anacy_2691	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anacy_2695	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Anacy_2699	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
Anacy_2701	ENOG4107RIQ	Sulfate adenylate transferase
Anacy_2707	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Anacy_2714	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
Anacy_2716	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Anacy_2718	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anacy_2719	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Anacy_2724	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anacy_2725	ENOG4105C19	ABC transporter
Anacy_2727	ENOG4105MKU	Transcriptional regulator
Anacy_2729	ENOG4105D0S	secretion protein (HlyD
Anacy_2730	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anacy_2731	ENOG4105C19	ABC transporter
Anacy_2733	ENOG4105WH1	Two component transcriptional regulator luxr family
Anacy_2734	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anacy_2738	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
Anacy_2741	ENOG4108YZN	class I peptide chain release factor
Anacy_2744	ENOG4105CAK	Cell division ATP-binding protein ftsE
Anacy_2746	ENOG4105EKQ	RNA-directed DNA polymerase
Anacy_2752	ENOG4105ERG	peptidase m48, ste24p
Anacy_2761	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Anacy_2775	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Anacy_2776	ENOG4107VDP	teichoic acid biosynthesis
Anacy_2779	ENOG4105K63	Thioredoxin
Anacy_2781	ENOG4105DUM	transcriptional regulator, lysR family
Anacy_2783	ENOG4105CVA	phosphate
Anacy_2785	ENOG4108RCM	Nitroreductase
Anacy_2786	ENOG4105CVA	phosphate
Anacy_2788	ENOG4105C75	arginyL-tRNA synthetase
Anacy_2789	ENOG410667J	hydrolase
Anacy_2791	ENOG410620I	Diguanylate cyclase
Anacy_2797	ENOG4105J0U	photosystem II
Anacy_2798	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Anacy_2801	ENOG4105C8S	subunit m
Anacy_2812	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Anacy_2817	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Anacy_2818	ENOG4105W8H	transhydrogenase (subunit alpha
Anacy_2819	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Anacy_2821	ENOG4107ETG	50S ribosomal protein L34
Anacy_2822	ENOG41082ZZ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Anacy_2824	ENOG4107RIX	inner membrane protein translocase component YidC
Anacy_2835	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Anacy_2838	ENOG4105EYH	Exonuclease
Anacy_2842	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_2848	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
Anacy_2849	ENOG4105CHV	Transcription elongation factor NusA
Anacy_2852	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Anacy_2854	ENOG4108SHJ	s-layer protein
Anacy_2862	ENOG4105DZR	Type I site-specific deoxyribonuclease
Anacy_2886	ENOG4105ETX	regulatoR
Anacy_2887	ENOG4105BZU	Histidine kinase
Anacy_2890	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
Anacy_2891	ENOG4105BZU	Histidine kinase
Anacy_2892	ENOG4105CTK	cobaltochelatase, cobn subunit
Anacy_2894	ENOG4107XWZ	ferric uptake regulator
Anacy_2895	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anacy_2896	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Anacy_2897	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Anacy_2898	ENOG4105BZU	Histidine kinase
Anacy_2904	ENOG4108302	MgtC SapB transporter
Anacy_2906	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Anacy_2907	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
Anacy_2911	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Anacy_2917	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
Anacy_2924	ENOG4108JJB	ABC transporter
Anacy_2926	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
Anacy_2932	ENOG4105E3B	Multicopper oxidase
Anacy_2938	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Anacy_2939	ENOG410801B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Anacy_2941	ENOG4105C7Z	Conserved Protein
Anacy_2943	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Anacy_2949	ENOG4105CNF	WD-40 repeat protein
Anacy_2950	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Anacy_2951	ENOG4105CAS	nag kinase
Anacy_2955	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Anacy_2959	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
Anacy_2960	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Anacy_2961	ENOG4107TS3	membrane protein, TerC
Anacy_2969	ENOG4108UK5	Transposase
Anacy_2971	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Anacy_2980	ENOG4105TQG	cytochrome C, class I
Anacy_2984	ENOG4108KQJ	Type 11 methyltransferase
Anacy_2987	ENOG410848W	30S ribosomal protein S21
Anacy_2996	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Anacy_2997	ENOG4105MKQ	Monovalent cation H antiporter subunit C
Anacy_2999	ENOG4105E5Q	amino acid AbC transporter
Anacy_3002	ENOG4105BZU	Histidine kinase
Anacy_3007	ENOG4108RXX	maleylacetoacetate isomerase
Anacy_3018	ENOG4105C8N	cysteinyl-tRNA synthetase
Anacy_3022	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Anacy_3027	ENOG4108JQC	penicillin-binding protein 1A
Anacy_3028	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Anacy_3029	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Anacy_3036	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Anacy_3039	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Anacy_3040	ENOG4105KVH	Transcriptional regulator
Anacy_3045	ENOG4108UV1	cellular component movement
Anacy_3047	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Anacy_3049	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Anacy_3051	ENOG4105CW7	secretion protein, HlyD family
Anacy_3053	ENOG4108JA1	polyketide synthase
Anacy_3055	ENOG4107QKG	PfaD family
Anacy_3059	ENOG4107P5I	polyketide synthase
Anacy_3068	ENOG4105DMQ	Methyltransferase
Anacy_3071	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
Anacy_3076	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Anacy_3085	ENOG4105CQR	helicase
Anacy_3088	ENOG4108Z6Z	Transcriptional regulator
Anacy_3091	ENOG4105C59	p-type ATPase
Anacy_3098	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Anacy_3101	ENOG4108MBK	is1 orf2
Anacy_3102	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Anacy_3104	ENOG4105BZU	Histidine kinase
Anacy_3105	ENOG4105CYM	Glutathione S-transferase
Anacy_3106	ENOG4108IJ6	ABC transporter
Anacy_3107	ENOG4105CA3	membrane-bound lytic murein transglycosylase
Anacy_3109	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
Anacy_3114	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Anacy_3127	ENOG4105CB5	ATP-dependent DNA helicase recG
Anacy_3129	ENOG4105BZU	Histidine kinase
Anacy_3130	ENOG4107WDG	serine threonine protein kinase
Anacy_3131	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Anacy_3132	ENOG4105EMU	Dehydrogenase
Anacy_3134	ENOG4105D7N	magnesium and cobalt transport protein CorA
Anacy_3137	ENOG41086DT	Membrane protein of unknown function
Anacy_3139	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Anacy_3141	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Anacy_3142	ENOG4105E2Z	phosphate ABC transporter (Permease
Anacy_3143	ENOG4105C8U	phosphate abc transporter
Anacy_3144	ENOG4105PWN	phosphate abc transporter
Anacy_3145	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
Anacy_3147	ENOG4108W6C	Dehydrogenase
Anacy_3148	ENOG4107P5I	polyketide synthase
Anacy_3149	ENOG4107QKG	PfaD family
Anacy_3152	ENOG4105C0W	non-ribosomal peptide synthetase
Anacy_3153	ENOG4108JA1	polyketide synthase
Anacy_3160	ENOG4105D5T	phosphonate abc transporter
Anacy_3161	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
Anacy_3167	ENOG4105FD8	phosphonate metabolism protein PhnM
Anacy_3168	ENOG4105FT8	Phosphonate metabolism
Anacy_3169	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
Anacy_3170	ENOG4105HRV	phosphonate c-p lyase system protein phnl
Anacy_3171	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anacy_3172	ENOG4105M3Z	response regulator
Anacy_3175	ENOG4105CBS	Chea signal transduction histidine kinase
Anacy_3177	ENOG4105F38	ABC transporter, permease
Anacy_3179	ENOG4107RUE	extracellular solute-binding protein family 1
Anacy_3180	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Anacy_3181	ENOG4107RVG	penicillin-binding protein
Anacy_3184	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
Anacy_3191	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
Anacy_3196	ENOG4107T8Q	Glycosyl transferase (Group 1
Anacy_3199	ENOG4105EY8	ABC transporter
Anacy_3204	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Anacy_3205	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
Anacy_3206	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Anacy_3207	ENOG4105DR5	peptidase
Anacy_3209	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
Anacy_3210	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Anacy_3216	ENOG4105CBX	hi0933 family
Anacy_3219	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Anacy_3220	ENOG4105D5K	Hemolysin activator protein
Anacy_3223	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Anacy_3230	ENOG4105PSV	Polysaccharide Biosynthesis Protein
Anacy_3237	ENOG41082AN	stage II sporulation protein
Anacy_3238	ENOG4105ETX	regulatoR
Anacy_3239	ENOG4105BZU	Histidine kinase
Anacy_3245	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Anacy_3251	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Anacy_3257	ENOG4105BZ1	(ABC) transporter
Anacy_3259	ENOG4105BZU	Histidine kinase
Anacy_3261	ENOG4105K63	Thioredoxin
Anacy_3266	ENOG4105KVH	Transcriptional regulator
Anacy_3269	ENOG41083MR	nifu domain-containing protein
Anacy_3273	ENOG4105CFG	Acts as a chaperone (By similarity)
Anacy_3284	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Anacy_3285	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anacy_3287	ENOG4105BZU	Histidine kinase
Anacy_3289	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Anacy_3295	ENOG4105C9M	aspartyl-trna synthetase
Anacy_3296	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Anacy_3301	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Anacy_3304	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Anacy_3305	ENOG4105BZU	Histidine kinase
Anacy_3308	ENOG4105C8Y	Acetylornithine aminotransferase
Anacy_3310	ENOG4108XI2	Domain of unknown function (DUF1963)
Anacy_3317	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Anacy_3327	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Anacy_3334	ENOG4108IXY	short-chain dehydrogenase reductase
Anacy_3335	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Anacy_3339	ENOG4105EHU	Circadian clock protein KaiC
Anacy_3340	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
Anacy_3341	ENOG4108WXF	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation
Anacy_3342	ENOG4105BZU	Histidine kinase
Anacy_3343	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Anacy_3346	ENOG4105DBI	uridine monophosphokinase
Anacy_3347	ENOG4105BZU	Histidine kinase
Anacy_3351	ENOG4105CNG	UPF0061 protein
Anacy_3352	ENOG4105D9U	N-acetyltransferase
Anacy_3353	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Anacy_3355	ENOG4105D49	3-dehydroquinate synthase
Anacy_3356	ENOG4106A3M	Cytochrome p-450
Anacy_3362	ENOG4105C3G	gtp-binding protein
Anacy_3363	ENOG4105D9P	serine threonine protein kinase
Anacy_3369	ENOG4105EGD	dinuclear metal center protein, YbgI family
Anacy_3370	ENOG4108V5V	Serine Threonine protein kinase
Anacy_3373	ENOG4105C9B	Cysteine desulfurase
Anacy_3382	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
Anacy_3383	ENOG4105F32	YngK protein
Anacy_3384	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Anacy_3388	ENOG4105DRS	transport system, permease
Anacy_3389	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
Anacy_3391	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Anacy_3393	ENOG4105EUJ	GTP cyclohydrolase i
Anacy_3398	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Anacy_3399	ENOG4106INZ	Photosystem I reaction center subunit
Anacy_3403	ENOG4105DR5	peptidase
Anacy_3405	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
Anacy_3406	ENOG4105EMN	RNA polymerase sigma factor
Anacy_3408	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Anacy_3410	ENOG4105CH5	extracellular solute-binding protein, family 7
Anacy_3411	ENOG4105E6M	Sulphatase-modifying factor protein
Anacy_3413	ENOG4105C8T	Leucyl-tRNA synthetase
Anacy_3421	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Anacy_3422	ENOG4105CDU	Replicative dna helicase
Anacy_3423	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Anacy_3424	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Anacy_3428	ENOG4105BZ1	(ABC) transporter
Anacy_3429	ENOG4107EF8	Glycosyl transferase (Group 1
Anacy_3435	ENOG4105CD8	aminopeptidase N
Anacy_3446	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Anacy_3447	ENOG41066AK	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
Anacy_3454	ENOG4105M0M	Tetracycline resistance protein
Anacy_3455	ENOG4108JJB	ABC transporter
Anacy_3456	ENOG4105VUV	UPF0367 protein
Anacy_3457	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
Anacy_3458	ENOG4108PWY	Carbohydrate-selective porin OprB
Anacy_3461	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anacy_3468	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Anacy_3469	ENOG4108N5B	2-phosphosulfolactate phosphatase
Anacy_3471	ENOG4105IJJ	transcriptional regulator, crp fnr family
Anacy_3477	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
Anacy_3484	ENOG4105C5H	ABC transporter
Anacy_3488	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Anacy_3491	ENOG4105D0S	secretion protein (HlyD
Anacy_3492	ENOG4108IG5	Transcriptional regulator
Anacy_3500	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Anacy_3501	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Anacy_3503	ENOG4105BZU	Histidine kinase
Anacy_3504	ENOG4105KZX	Pterin carbinolamine dehydratase
Anacy_3524	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_3526	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
Anacy_3528	ENOG4108UK5	Transposase
Anacy_3530	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Anacy_3535	ENOG4105D9P	serine threonine protein kinase
Anacy_3536	ENOG4107S5T	Carbohydrate kinase
Anacy_3542	ENOG4105CYM	Glutathione S-transferase
Anacy_3543	ENOG4108VPT	UPF0234 protein
Anacy_3548	ENOG4105CND	Glycosyl transferase, family 2
Anacy_3549	ENOG4108RT4	succinoglycan biosynthesis
Anacy_3560	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Anacy_3565	ENOG4108ZAF	Molybdopterin
Anacy_3568	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Anacy_3582	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Anacy_3587	ENOG4105C7K	acetolactate synthase
Anacy_3589	ENOG4105F8J	Adenylate Guanylate cyclase
Anacy_3591	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
Anacy_3596	ENOG4105EIE	fructose-bisphosphate aldolase
Anacy_3599	ENOG4108SHJ	s-layer protein
Anacy_3601	ENOG4105DGU	Histone deacetylase
Anacy_3608	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Anacy_3614	ENOG4107SBE	Glycosyl transferase (Group 1
Anacy_3616	ENOG4105K64	Glycosyl transferase, family 2
Anacy_3618	ENOG4107QJE	Chromosome Partitioning Protein
Anacy_3619	ENOG4107QJE	Chromosome Partitioning Protein
Anacy_3621	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Anacy_3633	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Anacy_3635	ENOG4108J2P	Alpha beta hydrolase fold
Anacy_3641	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Anacy_3642	ENOG41082AN	stage II sporulation protein
Anacy_3643	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Anacy_3647	ENOG4105BZU	Histidine kinase
Anacy_3648	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Anacy_3651	ENOG41081UC	Inherit from COG: Competence protein
Anacy_3669	ENOG4105CPK	Glycosyl transferase (Group 1
Anacy_3670	ENOG4107T8Q	Glycosyl transferase (Group 1
Anacy_3673	ENOG4105CAY	ferredoxin--nadp reductase
Anacy_3682	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
Anacy_3683	ENOG4105CZX	twitching motility protein
Anacy_3688	ENOG41061JJ	Peptidase family M23
Anacy_3693	ENOG4105BZU	Histidine kinase
Anacy_3695	ENOG4105BZU	Histidine kinase
Anacy_3696	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Anacy_3697	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
Anacy_3699	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Anacy_3706	ENOG4105C9X	ppx gppa phosphatase
Anacy_3707	ENOG4105D9P	serine threonine protein kinase
Anacy_3709	ENOG4108M24	von Willebrand factor, type A
Anacy_3716	ENOG4107R73	Mate efflux family protein
Anacy_3717	ENOG41067B5	Histone deacetylase superfamily protein
Anacy_3719	ENOG4105CQC	Prephenate dehydratase
Anacy_3725	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Anacy_3730	ENOG4108S64	thioredoxin-like protein txlA
Anacy_3735	ENOG4105CTK	cobaltochelatase, cobn subunit
Anacy_3742	ENOG4105DQ5	transport system permease protein
Anacy_3743	ENOG4108U1V	ABC transporter, permease
Anacy_3744	ENOG4105E0A	ABC, transporter
Anacy_3750	ENOG4105D7V	transposase
Anacy_3756	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
Anacy_3757	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
Anacy_3759	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Anacy_3762	ENOG4105CNI	cell division protein FtsW
Anacy_3766	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Anacy_3767	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Anacy_3769	ENOG4108QV3	biosynthesis protein
Anacy_3772	ENOG4105CPK	Glycosyl transferase (Group 1
Anacy_3779	ENOG4108UW5	maltose o-acetyltransferase
Anacy_3781	ENOG4105K64	Glycosyl transferase, family 2
Anacy_3785	ENOG4107Y2G	Glycosyl transferase (Group 1
Anacy_3789	ENOG4108SHN	Glycosyl transferase, family 2
Anacy_3791	ENOG4105EY8	ABC transporter
Anacy_3792	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
Anacy_3796	ENOG4105CEV	competence damage-inducible protein
Anacy_3797	ENOG4105ESV	Glycosyl transferase, family 4
Anacy_3798	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Anacy_3802	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
Anacy_3804	ENOG41082AN	stage II sporulation protein
Anacy_3806	ENOG4105CDH	Citrulline--aspartate ligase
Anacy_3812	ENOG4105K64	Glycosyl transferase, family 2
Anacy_3818	ENOG4105CE9	30S ribosomal protein S2
Anacy_3820	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Anacy_3824	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Anacy_3826	ENOG4105CKK	Glycosyl transferase, family 2
Anacy_3827	ENOG4105C6X	Major Facilitator
Anacy_3828	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Anacy_3831	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anacy_3837	ENOG4107QRP	cobalamin biosynthesis protein CobW
Anacy_3844	ENOG4105EWN	Heme oxygenase
Anacy_3845	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Anacy_3847	ENOG4108PQP	glycosyl transferase group 1
Anacy_3848	ENOG4107RGC	Glycosyl transferase, family 2
Anacy_3849	ENOG4105CPK	Glycosyl transferase (Group 1
Anacy_3850	ENOG4105JNK	Glycosyl transferase (Group 1
Anacy_3851	ENOG4105D3R	alkyl hydroperoxide reductase
Anacy_3863	ENOG410890F	Dynamin family
Anacy_3864	ENOG410890F	Dynamin family
Anacy_3871	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Anacy_3876	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Anacy_3878	ENOG4105CEC	DNA methylase N-4 N-6
Anacy_3880	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Anacy_3881	ENOG4105WZW	rhodanese family
Anacy_3884	ENOG4108MBK	is1 orf2
Anacy_3887	ENOG4105BZU	Histidine kinase
Anacy_3891	ENOG41085RW	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Anacy_3902	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Anacy_3907	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Anacy_3908	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
Anacy_3910	ENOG4108KMV	Glycosyl transferase (Group 1
Anacy_3912	ENOG4105C5H	ABC transporter
Anacy_3918	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
Anacy_3919	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Anacy_3920	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Anacy_3921	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Anacy_3922	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Anacy_3923	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Anacy_3924	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Anacy_3925	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Anacy_3926	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Anacy_3927	ENOG410848H	50s ribosomal protein l29
Anacy_3928	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Anacy_3929	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Anacy_3930	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Anacy_3931	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Anacy_3932	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Anacy_3933	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Anacy_3934	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Anacy_3935	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Anacy_3936	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Anacy_3937	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Anacy_3938	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Anacy_3940	ENOG41067V7	50S ribosomal protein L36
Anacy_3941	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Anacy_3942	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Anacy_3943	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Anacy_3944	ENOG4108ZT0	50S ribosomal protein l17
Anacy_3945	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Anacy_3946	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Anacy_3947	ENOG4108UJD	30S ribosomal protein S9
Anacy_3948	ENOG41082HT	Binds the 23S rRNA (By similarity)
Anacy_3949	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Anacy_3953	ENOG4105D85	methylase
Anacy_3959	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Anacy_3960	ENOG4105EPW	hflc protein
Anacy_3962	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Anacy_3964	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Anacy_3965	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Anacy_3966	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Anacy_3967	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Anacy_3968	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Anacy_3969	ENOG4107QPR	SAICAR synthetase
Anacy_3972	ENOG4105F8J	Adenylate Guanylate cyclase
Anacy_3995	ENOG4105BZU	Histidine kinase
Anacy_4004	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
Anacy_4026	ENOG4105C8S	subunit m
Anacy_4033	ENOG4105C8S	subunit m
Anacy_4040	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Anacy_4047	ENOG4106CD9	glycosyl transferase group 1
Anacy_4049	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Anacy_4052	ENOG4107QXX	ABC transporter
Anacy_4053	ENOG4105EZ7	amino acid ABC transporter
Anacy_4054	ENOG4105DRP	amino acid AbC transporter
Anacy_4055	ENOG4105CDA	abc transporter atp-binding protein
Anacy_4067	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
Anacy_4069	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
Anacy_4076	ENOG4105E0A	ABC, transporter
Anacy_4077	ENOG4105EHG	Permease protein
Anacy_4080	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Anacy_4082	ENOG4105CA0	peroxidase
Anacy_4084	ENOG4107ZSV	Receptor
Anacy_4088	ENOG4108JJA	ABC, transporter
Anacy_4089	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
Anacy_4104	ENOG4107ZBH	radical SAM domain protein
Anacy_4111	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Anacy_4112	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
Anacy_4120	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Anacy_4121	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Anacy_4122	ENOG4105BZU	Histidine kinase
Anacy_4124	ENOG4105BZU	Histidine kinase
Anacy_4126	ENOG4105PGM	cation diffusion facilitator family transporter
Anacy_4130	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Anacy_4135	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Anacy_4136	ENOG4105C8M	UPF0272 protein
Anacy_4144	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Anacy_4150	ENOG4105CJW	magnesium transporter
Anacy_4151	ENOG4105CXT	aspartate transcarbamylase
Anacy_4155	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Anacy_4163	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Anacy_4167	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anacy_4169	ENOG41086B8	CoB-CoM heterodisulfide reductase
Anacy_4170	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Anacy_4172	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Anacy_4173	ENOG4105BZU	Histidine kinase
Anacy_4174	ENOG4105BZU	Histidine kinase
Anacy_4176	ENOG4105BZU	Histidine kinase
Anacy_4177	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
Anacy_4179	ENOG4105E18	UPF0276 protein
Anacy_4181	ENOG4105EYW	Ion transport protein
Anacy_4182	ENOG4108Z6B	deaminase
Anacy_4188	ENOG4105WH1	Two component transcriptional regulator luxr family
Anacy_4189	ENOG4105BZU	Histidine kinase
Anacy_4192	ENOG4107R73	Mate efflux family protein
Anacy_4194	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Anacy_4196	ENOG4105CSR	polyphosphate kinase 2
Anacy_4197	ENOG4107Z5C	methylesterase
Anacy_4198	ENOG4105BZU	Histidine kinase
Anacy_4201	ENOG4105BZU	Histidine kinase
Anacy_4202	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_4203	ENOG4105ETX	regulatoR
Anacy_4232	ENOG4107STW	synthase
Anacy_4246	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
Anacy_4247	ENOG4105CD5	CoA-binding domain protein
Anacy_4253	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anacy_4256	ENOG4107QIZ	NADH dehydrogenase
Anacy_4259	ENOG4105BZ1	(ABC) transporter
Anacy_4260	ENOG4108HUF	Transporter
Anacy_4261	ENOG4105E0K	tonB-dependent siderophore receptor
Anacy_4262	ENOG4105WPR	Transcriptional regulator, ARAC family
Anacy_4265	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Anacy_4268	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anacy_4271	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Anacy_4274	ENOG41067SE	Tetr family transcriptional regulator
Anacy_4281	ENOG4105BZU	Histidine kinase
Anacy_4282	ENOG41063FQ	CsbD-like protein
Anacy_4283	ENOG41063FQ	CsbD-like protein
Anacy_4287	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anacy_4289	ENOG4105C37	(CBS) domain
Anacy_4290	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Anacy_4292	ENOG4107T5V	SNARE associated Golgi
Anacy_4299	ENOG4105FFC	UPF0187 protein
Anacy_4300	ENOG4107VAM	peptidase, m28
Anacy_4301	ENOG4108KBA	Acts as a chaperone (By similarity)
Anacy_4303	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anacy_4305	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Anacy_4306	ENOG4105C8B	TIGR00159 family
Anacy_4311	ENOG4107Z12	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Anacy_4313	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Anacy_4314	ENOG4107JEG	This protein is a component of the reaction center of photosystem II (By similarity)
Anacy_4316	ENOG4106DDF	Photosystem II reaction center protein M
Anacy_4317	ENOG4108U51	Universal stress protein
Anacy_4318	ENOG4107S6X	Glycosyl transferase, family 2
Anacy_4319	ENOG4105D5K	Hemolysin activator protein
Anacy_4323	ENOG4105DGW	oligopeptidase A
Anacy_4325	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Anacy_4329	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Anacy_4334	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_4350	ENOG4105CZX	twitching motility protein
Anacy_4351	ENOG4107QHF	type ii secretion system protein e
Anacy_4352	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Anacy_4353	ENOG4105CFG	Acts as a chaperone (By similarity)
Anacy_4354	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anacy_4356	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Anacy_4357	ENOG4107RFW	hydrolase family 57
Anacy_4360	ENOG4105D9P	serine threonine protein kinase
Anacy_4368	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
Anacy_4373	ENOG41072GX	Peptidase M22 Glycoprotease
Anacy_4375	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Anacy_4381	ENOG4108JQC	penicillin-binding protein 1A
Anacy_4384	ENOG4108UMY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Anacy_4388	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Anacy_4392	ENOG4105BZU	Histidine kinase
Anacy_4394	ENOG4108HGU	Histidine kinase
Anacy_4397	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Anacy_4404	ENOG4105DXN	mazG family
Anacy_4405	ENOG4107R0W	ABC transporter
Anacy_4413	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Anacy_4416	ENOG4105E4F	Isochorismate synthase
Anacy_4419	ENOG4105CEY	Amp-dependent synthetase and ligase
Anacy_4420	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
Anacy_4432	ENOG4105C0P	Mg chelatase subunit ChlI
Anacy_4434	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Anacy_4435	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Anacy_4438	ENOG4105CE4	GlcNAc 6-P deacetylase
Anacy_4452	ENOG4107QRT	dEAD DEAH box helicase
Anacy_4453	ENOG4107WDG	serine threonine protein kinase
Anacy_4463	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Anacy_4464	ENOG4105D0M	Protease HtpX homolog
Anacy_4470	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Anacy_4478	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anacy_4481	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
Anacy_4489	ENOG4108Z03	MAF-like protein
Anacy_4491	ENOG4105E66	phosphoriboisomerase A
Anacy_4493	ENOG4105CIJ	rieske 2fe-2S domain-containing protein
Anacy_4495	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
Anacy_4496	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Anacy_4497	ENOG4105DF7	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Anacy_4498	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
Anacy_4505	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
Anacy_4506	ENOG410715G	filament integrity protein
Anacy_4507	ENOG4105RRH	
Anacy_4510	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Anacy_4511	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Anacy_4512	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Anacy_4518	ENOG4105C1G	acyl-Coa dehydrogenase
Anacy_4519	ENOG4107SQU	synthase
Anacy_4520	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Anacy_4524	ENOG4105D65	subunit l
Anacy_4526	ENOG4105C8S	subunit m
Anacy_4529	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
Anacy_4534	ENOG4105BZU	Histidine kinase
Anacy_4535	ENOG4105DWF	phosphomethylpyrimidine kinase
Anacy_4544	ENOG4105D3G	Pseudouridine synthase
Anacy_4545	ENOG4105BZU	Histidine kinase
Anacy_4554	ENOG4105C5R	Aminotransferase
Anacy_4557	ENOG4105E2K	Glycosyl transferase (Group 1
Anacy_4558	ENOG4105D38	putrescine abc transporter
Anacy_4560	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_4561	ENOG4105ETX	regulatoR
Anacy_4564	ENOG4105BZU	Histidine kinase
Anacy_4569	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
Anacy_4574	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Anacy_4575	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Anacy_4577	ENOG4108062	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Anacy_4578	ENOG4107QHF	type ii secretion system protein e
Anacy_4580	ENOG4105DDG	Cyanophycinase
Anacy_4582	ENOG4105C6E	dna polymerase iii
Anacy_4593	ENOG4108IUZ	ABC transporter
Anacy_4604	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Anacy_4609	ENOG4108JJA	ABC, transporter
Anacy_4614	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Anacy_4615	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Anacy_4624	ENOG4105CJ1	ABC, transporter
Anacy_4628	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Anacy_4632	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Anacy_4635	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Anacy_4640	ENOG4105BZU	Histidine kinase
Anacy_4641	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Anacy_4648	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Anacy_4654	ENOG4105BZU	Histidine kinase
Anacy_4655	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Anacy_4667	ENOG4105HFZ	Membrane
Anacy_4670	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Anacy_4672	ENOG4105DDQ	anthranilate synthase
Anacy_4678	ENOG4107RAQ	aminopeptidase
Anacy_4681	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Anacy_4682	ENOG4105E0R	Deoxyhypusine synthase
Anacy_4683	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Anacy_4685	ENOG4108HMN	Caspase domain
Anacy_4686	ENOG4108IJ6	ABC transporter
Anacy_4700	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Anacy_4704	ENOG4105BZU	Histidine kinase
Anacy_4706	ENOG4105D82	Glutamate dehydrogenase
Anacy_4710	ENOG41082T9	Membrane
Anacy_4714	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Anacy_4715	ENOG4105N7N	Pentapeptide repeat-containing protein
Anacy_4717	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Anacy_4718	ENOG4105BZU	Histidine kinase
Anacy_4721	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
Anacy_4723	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Anacy_4726	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Anacy_4731	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Anacy_4735	ENOG4105CJN	penicillin-binding protein
Anacy_4740	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Anacy_4744	ENOG4108WHG	pyridoxamine 5'-phosphate
Anacy_4750	ENOG4105WH1	Two component transcriptional regulator luxr family
Anacy_4752	ENOG4105CD2	stage iii sporulation protein aa
Anacy_4754	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Anacy_4755	ENOG4105ESV	Glycosyl transferase, family 4
Anacy_4760	ENOG4105VCQ	rubredoxin
Anacy_4761	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Anacy_4762	ENOG4105JNK	Glycosyl transferase (Group 1
Anacy_4773	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
Anacy_4775	ENOG4105CXI	aluminum resistance protein
Anacy_4784	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Anacy_4790	ENOG4105DFK	Polyphosphate glucokinase
Anacy_4795	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Anacy_4797	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Anacy_4798	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Anacy_4810	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Anacy_4814	ENOG4108F3G	Type I restriction-modification system, R subunit
Anacy_4818	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anacy_4819	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_4820	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Anacy_4823	ENOG4105BZU	Histidine kinase
Anacy_4830	ENOG4105BZU	Histidine kinase
Anacy_4835	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Anacy_4845	ENOG4105DBV	ornithine carbamoyltransferase
Anacy_4847	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
Anacy_4852	ENOG4108SHJ	s-layer protein
Anacy_4859	ENOG4105EYH	Exonuclease
Anacy_4862	ENOG4105EYM	Major Facilitator superfamily
Anacy_4865	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
Anacy_4867	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
Anacy_4868	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Anacy_4869	ENOG4105BZU	Histidine kinase
Anacy_4870	ENOG4105BZU	Histidine kinase
Anacy_4872	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Anacy_4875	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
Anacy_4876	ENOG4108IYU	L-aspartate oxidase
Anacy_4878	ENOG4105BZU	Histidine kinase
Anacy_4879	ENOG4105CVB	Vitamin K epoxide reductase
Anacy_4881	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Anacy_4886	ENOG4105XCI	PucC protein
Anacy_4891	ENOG4105ECY	inositol monophosphatase
Anacy_4897	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
Anacy_4905	ENOG4105D5D	udp-galactopyranose mutase
Anacy_4907	ENOG410602S	Transferase
Anacy_4910	ENOG4105EY8	ABC transporter
Anacy_4915	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anacy_4929	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Anacy_4931	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Anacy_4932	ENOG4107U45	Cobalt transport protein
Anacy_4940	ENOG4108YRB	methyltransferase
Anacy_4948	ENOG4105BZU	Histidine kinase
Anacy_4949	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_4950	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Anacy_4955	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
Anacy_4961	ENOG4107WDG	serine threonine protein kinase
Anacy_4963	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Anacy_4974	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
Anacy_4979	ENOG4105G6Z	alkaline phosphatase
Anacy_4980	ENOG4105EHG	Permease protein
Anacy_4983	ENOG4105E0A	ABC, transporter
Anacy_4986	ENOG4105D6A	Electron transport complex
Anacy_4992	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
Anacy_4993	ENOG4106WTF	Glycosyl transferase, family 2
Anacy_4994	ENOG4108SHN	Glycosyl transferase, family 2
Anacy_5000	ENOG4108JJA	ABC, transporter
Anacy_5003	ENOG4105WH1	Two component transcriptional regulator luxr family
Anacy_5005	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Anacy_5006	ENOG4107YJ4	chain length determinant protein
Anacy_5007	ENOG4105JFG	SpoIID LytB domain protein
Anacy_5014	ENOG4108FN7	Aldo keto reductase
Anacy_5022	ENOG4105DHJ	ABC, transporter
Anacy_5023	ENOG4105E2X	shikimate dehydrogenase
Anacy_5026	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Anacy_5028	ENOG4105YVZ	photosystem II
Anacy_5034	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Anacy_5038	ENOG4105CFG	Acts as a chaperone (By similarity)
Anacy_5042	ENOG4108YZ3	Glyoxalase Bleomycin resistance protein (Dioxygenase
Anacy_5045	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Anacy_5050	ENOG4105CHM	Aminotransferase
Anacy_5053	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
Anacy_5058	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Anacy_5059	ENOG41084A0	50s ribosomal protein L35
Anacy_5061	ENOG4107QKA	exodeoxyribonuclease V beta
Anacy_5064	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anacy_5065	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
Anacy_5066	ENOG4106MP8	UPF0754 membrane protein
Anacy_5068	ENOG4105DCF	alanine dehydrogenase
Anacy_5069	ENOG4105CNF	WD-40 repeat protein
Anacy_5072	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Anacy_5076	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Anacy_5082	ENOG4105F8J	Adenylate Guanylate cyclase
Anacy_5093	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Anacy_5094	ENOG4105D8X	mechanosensitive ion channel
Anacy_5108	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Anacy_5110	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Anacy_5115	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Anacy_5116	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Anacy_5117	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Anacy_5120	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Anacy_5121	ENOG4105CB5	ATP-dependent DNA helicase recG
Anacy_5123	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Anacy_5127	ENOG4107WZZ	SMC domain protein
Anacy_5133	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anacy_5135	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Anacy_5136	ENOG4105BZU	Histidine kinase
Anacy_5137	ENOG4105BZU	Histidine kinase
Anacy_5141	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
Anacy_5142	ENOG41081F0	Precorrin-8x methylmutase
Anacy_5143	ENOG4105DVK	Precorrin-2 c20-methyltransferase
Anacy_5145	ENOG4107YU2	histidine triad (hIT) protein
Anacy_5147	ENOG4105Q84	sucrose synthase
Anacy_5167	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Anacy_5168	ENOG4105K63	Thioredoxin
Anacy_5173	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Anacy_5174	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Anacy_5177	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Anacy_5181	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Anacy_5182	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Anacy_5195	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Anacy_5197	ENOG4105FDP	GntR family transcriptional regulator
Anacy_5198	ENOG41068G9	50S ribosomal protein L32
Anacy_5202	ENOG4105CND	Glycosyl transferase, family 2
Anacy_5203	ENOG4105EWU	Squalene--hopene cyclase
Anacy_5206	ENOG4105D52	delta-aminolevulinic acid dehydratase
Anacy_5208	ENOG4105CKI	cobalamin synthesis protein
Anacy_5209	ENOG4105EUJ	GTP cyclohydrolase i
Anacy_5213	ENOG4105W5Q	DNA repair protein (RadC
Anacy_5215	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Anacy_5216	ENOG41084GG	50S ribosomal protein L33
Anacy_5219	ENOG4105CYP	glycoside hydrolase, family
Anacy_5221	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Anacy_5225	ENOG4105CXN	decarboxylase
Anacy_5239	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Anacy_5240	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Anacy_5241	ENOG4107EFQ	arachidonate 15-lipoxygenase
Anacy_5244	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Anacy_5245	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Anacy_5246	ENOG4105BZU	Histidine kinase
Anacy_5250	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Anacy_5255	ENOG4107RSM	transcriptional regulator
Anacy_5256	ENOG4105C01	Dihydroxy-acid dehydratase
Anacy_5259	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
Anacy_5263	ENOG4105C7B	Threonine dehydratase
Anacy_5266	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Anacy_5268	ENOG4105BZA	Phosphoglycerate kinase
Anacy_5275	ENOG4108MBK	is1 orf2
Anacy_5279	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
Anacy_5281	ENOG41083KH	UPF0102 protein
Anacy_5284	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Anacy_5286	ENOG4107ZYR	domain protein
Anacy_5287	ENOG4105CZN	Potassium uptake protein
Anacy_5291	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Anacy_5292	ENOG4108DIF	synthase (EC 4.2.1.75)
Anacy_5293	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Anacy_5295	ENOG4105BZU	Histidine kinase
Anacy_5296	ENOG4105BZU	Histidine kinase
Anacy_5306	ENOG4107WDG	serine threonine protein kinase
Anacy_5307	ENOG4105CNF	WD-40 repeat protein
Anacy_5315	ENOG4105H0Z	Hemerythrin HHE cation binding domain protein
Anacy_5316	ENOG4105BZ1	(ABC) transporter
Anacy_5317	ENOG4105DC8	reductase
Anacy_5323	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Anacy_5326	ENOG4107R4J	Chloride channel
Anacy_5332	ENOG4106H78	methyltransferase
Anacy_5333	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Anacy_5334	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Anacy_5339	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Anacy_5344	ENOG4105DG7	nitrate ABC transporter
Anacy_5348	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
Anacy_5353	ENOG4108HMN	Caspase domain
Anacy_5358	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anacy_5359	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Anacy_5360	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Anacy_5363	ENOG4107WDG	serine threonine protein kinase
Anacy_5364	ENOG4105CNF	WD-40 repeat protein
Anacy_5366	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Anacy_5373	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Anacy_5374	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Anacy_5377	ENOG4105VN1	Heat shock protein
Anacy_5389	ENOG4107QN1	sodium solute
Anacy_5393	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
Anacy_5394	ENOG4105VFU	Rna-binding protein
Anacy_5396	ENOG4105D2N	Aldolase
Anacy_5401	ENOG4107QWP	ABC-2 type transporter
Anacy_5409	ENOG4105CJ1	ABC, transporter
Anacy_5410	ENOG4105CJ1	ABC, transporter
Anacy_5417	ENOG4105C6E	dna polymerase iii
Anacy_5419	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Anacy_5420	ENOG4105BZU	Histidine kinase
Anacy_5421	ENOG4105CYM	Glutathione S-transferase
Anacy_5423	ENOG4105CF7	AraC family transcriptional regulator
Anacy_5425	ENOG4105ENX	hydrolase
Anacy_5426	ENOG4105EMU	Dehydrogenase
Anacy_5431	ENOG4105D9P	serine threonine protein kinase
Anacy_5432	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
Anacy_5445	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anacy_5447	ENOG4105WPR	Transcriptional regulator, ARAC family
Anacy_5448	ENOG4105E0K	tonB-dependent siderophore receptor
Anacy_5456	ENOG4108D32	Methyltransferase
Anacy_5463	ENOG41083PU	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Anacy_5466	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Anacy_5470	ENOG4105C1J	atp-dependent rna helicase
Anacy_5476	ENOG410890F	Dynamin family
Anacy_5479	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Anacy_5480	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Anacy_5488	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Anacy_5491	ENOG4108JQC	penicillin-binding protein 1A
Anacy_5493	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Anacy_5495	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Anacy_5496	ENOG4105C8U	phosphate abc transporter
Anacy_5497	ENOG4105E2Z	phosphate ABC transporter (Permease
Anacy_5498	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Anacy_5527	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Anacy_5531	ENOG4105KHC	sulfurtransferase
Anacy_5532	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Anacy_5533	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Anacy_5537	ENOG4105D44	asparaginase
Anacy_5540	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Anacy_5543	ENOG4107U9K	TROVE domain-containing protein
Anacy_5551	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Anacy_5553	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Anacy_5559	ENOG4105C5S	asparaginyl-tRNA synthetase
Anacy_5563	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Anacy_5564	ENOG4108S1Y	allophycocyanin alpha-B chain
Anacy_5565	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
Anacy_5566	ENOG4108YZ9	Urea amidohydrolase subunit gamma
Anacy_5567	ENOG4105KI2	Urea amidohydrolase subunit beta
Anacy_5568	ENOG4105CQM	Urea amidohydrolase subunit alpha
Anacy_5571	ENOG4105BZU	Histidine kinase
Anacy_5572	ENOG4105C26	Dehydrogenase
Anacy_5574	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Anacy_5575	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Anacy_5576	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Anacy_5578	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Anacy_5580	ENOG4108F5E	vimentin
Anacy_5587	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
Anacy_5591	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Anacy_5592	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Anacy_5593	ENOG4105CYW	agmatinase
Anacy_5601	ENOG4108UHE	carbonic anhydrase
Anacy_5611	ENOG4105DHP	deoxycytidine triphosphate deaminase
Anacy_5613	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Anacy_5620	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Anacy_5622	ENOG4105CEY	Amp-dependent synthetase and ligase
Anacy_5623	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Anacy_5624	ENOG4108UTZ	Dihydroxyacetone kinase
Anacy_5625	ENOG4105CMT	Dihydroxyacetone kinase
Anacy_5626	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Anacy_5641	ENOG4108I5C	dEAD DEAH box helicase
Anacy_5647	ENOG4105C6E	dna polymerase iii
Anacy_5651	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
Anacy_5673	ENOG4105VF7	tolerance protein
Anacy_5674	ENOG4108MBK	is1 orf2
Anacy_5695	ENOG4105C0D	helicase
Anacy_5702	ENOG4105BZU	Histidine kinase
Anacy_5703	ENOG4105WH1	Two component transcriptional regulator luxr family
Anacy_5709	ENOG4105PGZ	NB-ARC domain
Anacy_5710	ENOG4105EWK	phytoene
Anacy_5763	ENOG41064PG	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Anacy_5778	ENOG4105EKQ	RNA-directed DNA polymerase
Anacy_5782	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anacy_5785	ENOG4107U9H	DNA polymerase
Anacy_5792	ENOG4105BZU	Histidine kinase
Anacy_5793	ENOG4105ETX	regulatoR
Anacy_5805	ENOG4105BZU	Histidine kinase
Anacy_5807	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anacy_5809	ENOG4105PGM	cation diffusion facilitator family transporter
Anacy_5810	ENOG4105KJJ	Uncharacterized ACR, COG1993
Anacy_5815	ENOG4108PWY	Carbohydrate-selective porin OprB
Anacy_5823	ENOG4105BZU	Histidine kinase
Anacy_5827	ENOG41081F0	Precorrin-8x methylmutase
Anacy_5828	ENOG4105C59	p-type ATPase
Anacy_5830	ENOG4107Y80	Major Facilitator superfamily
Anacy_5836	ENOG4105WH1	Two component transcriptional regulator luxr family
Anacy_5870	ENOG4105FA0	parb-like partition protein
Anacy_5876	ENOG4105FA2	dna polymerase iii
Anacy_5883	ENOG4105C6E	dna polymerase iii
Anacy_5897	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Anacy_5924	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Anacy_5926	ENOG4105C7H	Helicase, RecD TraA family
Anacy_5936	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Anacy_5941	ENOG4105C59	p-type ATPase
Anacy_5942	ENOG4107QJE	Chromosome Partitioning Protein
Anacy_5968	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Anacy_5979	ENOG4105ETU	transcriptional activator (TenA
Anacy_5982	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anacy_5987	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Anacy_6051	ENOG4105CVR	type I restriction-modification system
Anacy_6054	ENOG4105EKX	Restriction modification system DNA (Specificity
Anacy_6058	ENOG4105DZR	Type I site-specific deoxyribonuclease
Anacy_6068	ENOG4108HMN	Caspase domain
Anacy_6078	ENOG4105CNF	WD-40 repeat protein
Anacy_6083	ENOG4105FA0	parb-like partition protein
Anacy_6093	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anacy_6094	ENOG4105CFG	Acts as a chaperone (By similarity)
Anacy_6111	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Anacy_6114	ENOG4105CMR	udp-glucose 4-epimerase
Anacy_6117	ENOG4107QJE	Chromosome Partitioning Protein
Anacy_6118	ENOG4105FA0	parb-like partition protein
Anacy_6128	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anacy_6154	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)