locus-tag	class	description
AA650_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AA650_00045	ENOG4105CFG	Acts as a chaperone (By similarity)
AA650_00060	ENOG4105W5K	Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity)
AA650_00080	ENOG4105EEK	Polypeptide
AA650_00095	ENOG4108QV3	biosynthesis protein
AA650_00100	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AA650_00120	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AA650_00145	ENOG4105D3Q	Sugar transferase
AA650_00165	ENOG4105CAQ	asparagine synthetase
AA650_00170	ENOG4105DDI	hemolysin-type calcium-binding region
AA650_00215	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AA650_00220	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AA650_00265	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AA650_00315	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AA650_00330	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA650_00360	ENOG4105D7N	magnesium and cobalt transport protein CorA
AA650_00365	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AA650_00375	ENOG4105BZ1	(ABC) transporter
AA650_00380	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AA650_00415	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AA650_00465	ENOG4105BZU	Histidine kinase
AA650_00500	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
AA650_00510	ENOG4108I6A	alcohol dehydrogenase
AA650_00525	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
AA650_00535	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AA650_00545	ENOG4105EUJ	GTP cyclohydrolase i
AA650_00550	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AA650_00555	ENOG4105VGQ	Photosystem I subunit X
AA650_00575	ENOG4105EWN	Heme oxygenase
AA650_00580	ENOG41066AK	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
AA650_00585	ENOG4105DSE	periplasmic solute binding protein
AA650_00590	ENOG4105DIK	(ABC) transporter
AA650_00595	ENOG4105CC5	ABC transporter
AA650_00620	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AA650_00625	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AA650_00665	ENOG4108F5E	vimentin
AA650_00685	ENOG4105D78	K07001 NTE family protein
AA650_00705	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
AA650_00710	ENOG4105C32	Amino acid ABC transporter (Permease)
AA650_00720	ENOG4105C0Z	ABC transporter
AA650_00725	ENOG4108IV0	ABC, transporter
AA650_00730	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AA650_00750	ENOG4105EET	magnesium chelatase
AA650_00780	ENOG4105C0H	protease
AA650_00825	ENOG4105CDU	Replicative dna helicase
AA650_00830	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AA650_00850	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AA650_00875	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AA650_00905	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
AA650_00915	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AA650_00920	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AA650_00925	ENOG4105C0D	helicase
AA650_00935	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AA650_00945	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
AA650_00960	ENOG4105BZU	Histidine kinase
AA650_00990	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AA650_01000	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_01025	ENOG4108302	MgtC SapB transporter
AA650_01030	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AA650_01040	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AA650_01070	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AA650_01095	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
AA650_01105	ENOG4107RCC	Major Facilitator Superfamily
AA650_01110	ENOG4105D49	3-dehydroquinate synthase
AA650_01115	ENOG4105E3B	Multicopper oxidase
AA650_01165	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
AA650_01175	ENOG4108JJB	ABC transporter
AA650_01195	ENOG4105D44	asparaginase
AA650_01205	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AA650_01245	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_01250	ENOG4105EB3	Histidine kinase
AA650_01260	ENOG4108PWY	Carbohydrate-selective porin OprB
AA650_01265	ENOG4105CRE	cytochrome C
AA650_01290	ENOG41072GX	Peptidase M22 Glycoprotease
AA650_01300	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AA650_01310	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AA650_01315	ENOG4105ERG	peptidase m48, ste24p
AA650_01365	ENOG4107U96	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AA650_01375	ENOG4105C8N	cysteinyl-tRNA synthetase
AA650_01390	ENOG4105CVJ	phosphoglycerate mutase
AA650_01395	ENOG4105CJN	penicillin-binding protein
AA650_01400	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AA650_01405	ENOG4107RUE	extracellular solute-binding protein family 1
AA650_01410	ENOG4105F38	ABC transporter, permease
AA650_01415	ENOG4107WDG	serine threonine protein kinase
AA650_01475	ENOG4105C7K	acetolactate synthase
AA650_01485	ENOG4105F8J	Adenylate Guanylate cyclase
AA650_01490	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AA650_01500	ENOG4107TE5	Lipid kinase
AA650_01510	ENOG4105CFG	Acts as a chaperone (By similarity)
AA650_01540	ENOG4105CVN	desaturase
AA650_01555	ENOG4107STW	synthase
AA650_01565	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AA650_01575	ENOG4107R1X	phosphohexokinase
AA650_01625	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA650_01640	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_01650	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_01655	ENOG4105D7V	transposase
AA650_01695	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
AA650_01700	ENOG4108PWY	Carbohydrate-selective porin OprB
AA650_01720	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA650_01745	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AA650_01750	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_01800	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AA650_01820	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AA650_01825	ENOG4108ZAF	Molybdopterin
AA650_01845	ENOG41087PP	glycosyltransferase MGT family
AA650_01860	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AA650_01870	ENOG4108UMY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AA650_01895	ENOG4105CFG	Acts as a chaperone (By similarity)
AA650_01900	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AA650_01905	ENOG4105JKW	Valine--pyruvate aminotransferase
AA650_01910	ENOG4107QPD	alcohol dehydrogenase
AA650_01955	ENOG4107QMH	DNA methylase
AA650_01975	ENOG4105C75	arginyL-tRNA synthetase
AA650_01985	ENOG4105VXP	Protein of unknown function DUF86
AA650_02015	ENOG4105C9X	ppx gppa phosphatase
AA650_02045	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AA650_02050	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AA650_02055	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AA650_02080	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AA650_02095	ENOG4105EHG	Permease protein
AA650_02100	ENOG4105E0A	ABC, transporter
AA650_02105	ENOG4105EMU	Dehydrogenase
AA650_02115	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AA650_02125	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
AA650_02175	ENOG4108JA1	polyketide synthase
AA650_02180	ENOG4105C0W	non-ribosomal peptide synthetase
AA650_02195	ENOG4107QKG	PfaD family
AA650_02200	ENOG4107P5I	polyketide synthase
AA650_02205	ENOG4108W6C	Dehydrogenase
AA650_02255	ENOG4105DBV	ornithine carbamoyltransferase
AA650_02270	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
AA650_02305	ENOG4108KBA	Acts as a chaperone (By similarity)
AA650_02310	ENOG4107VAM	peptidase, m28
AA650_02330	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
AA650_02365	ENOG4108IQE	Amp-dependent synthetase and ligase
AA650_02375	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AA650_02420	ENOG4105F4R	Transcriptional regulator mode
AA650_02425	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AA650_02445	ENOG4107TT5	NLP P60 protein
AA650_02455	ENOG4105CKK	Glycosyl transferase, family 2
AA650_02470	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_02490	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AA650_02515	ENOG4105CRQ	synthase (Component I)
AA650_02535	ENOG4105CJ1	ABC, transporter
AA650_02545	ENOG4107RAQ	aminopeptidase
AA650_02550	ENOG4105D7V	transposase
AA650_02555	ENOG4105CE9	30S ribosomal protein S2
AA650_02560	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AA650_02650	ENOG4108UXN	response regulator
AA650_02660	ENOG4105BZU	Histidine kinase
AA650_02675	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA650_02705	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AA650_02710	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AA650_02730	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AA650_02735	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AA650_02740	ENOG4107Z3D	50S ribosomal protein l10
AA650_02745	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AA650_02770	ENOG4105CXT	aspartate transcarbamylase
AA650_02775	ENOG4105CJW	magnesium transporter
AA650_02785	ENOG4105N7N	Pentapeptide repeat-containing protein
AA650_02790	ENOG4108KGH	TRANSCRIPTIONal
AA650_02795	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AA650_02805	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AA650_02810	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AA650_02820	ENOG4105FDP	GntR family transcriptional regulator
AA650_02840	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_02885	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AA650_02900	ENOG4107SC0	ferredoxin--NADP reductase
AA650_02935	ENOG4106HX1	Uncharacterised protein family (UPF0150)
AA650_02945	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AA650_02970	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AA650_02995	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA650_03015	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AA650_03040	ENOG4105K63	Thioredoxin
AA650_03065	ENOG4105CNF	WD-40 repeat protein
AA650_03080	ENOG4105C3M	thioredoxin reductase
AA650_03085	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AA650_03090	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AA650_03135	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AA650_03160	ENOG4105D9P	serine threonine protein kinase
AA650_03165	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AA650_03170	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AA650_03180	ENOG4107SDT	Homocitrate synthase
AA650_03190	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AA650_03220	ENOG4105C8S	subunit m
AA650_03255	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA650_03270	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AA650_03275	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
AA650_03280	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AA650_03285	ENOG4105ETX	regulatoR
AA650_03300	ENOG4105C9B	Cysteine desulfurase
AA650_03305	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AA650_03315	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AA650_03335	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AA650_03340	ENOG4105VUH	addiction module killer protein
AA650_03390	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AA650_03425	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AA650_03435	ENOG4105CBX	hi0933 family
AA650_03470	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AA650_03475	ENOG4107GBW	cellulosome anchoring protein cohesin
AA650_03490	ENOG41083MR	nifu domain-containing protein
AA650_03500	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
AA650_03505	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AA650_03510	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AA650_03525	ENOG4105E33	succinate dehydrogenase
AA650_03545	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AA650_03560	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AA650_03615	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AA650_03630	ENOG4107P5I	polyketide synthase
AA650_03640	ENOG4107QKG	PfaD family
AA650_03650	ENOG4108JA1	polyketide synthase
AA650_03670	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AA650_03675	ENOG4105CHR	reductase
AA650_03715	ENOG4105D7V	transposase
AA650_03725	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AA650_03735	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AA650_03760	ENOG4105CNI	cell division protein FtsW
AA650_03780	ENOG4105E6M	Sulphatase-modifying factor protein
AA650_03810	ENOG4108JQC	penicillin-binding protein 1A
AA650_03825	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA650_03830	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AA650_03835	ENOG4105D7W	serine acetyltransferase
AA650_03850	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AA650_03870	ENOG4105ECY	inositol monophosphatase
AA650_03890	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AA650_03895	ENOG4105Q36	FHA domain containing protein
AA650_03900	ENOG4105CAS	nag kinase
AA650_03930	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
AA650_04030	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AA650_04085	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AA650_04115	ENOG4105VN1	Heat shock protein
AA650_04165	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AA650_04175	ENOG4108K5P	(LipO)protein
AA650_04195	ENOG4105CMR	udp-glucose 4-epimerase
AA650_04230	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA650_04245	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AA650_04250	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AA650_04255	ENOG4105D0M	Protease HtpX homolog
AA650_04265	ENOG4107YJ4	chain length determinant protein
AA650_04275	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
AA650_04285	ENOG4107R0E	Glycosyl transferase, family 2
AA650_04290	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AA650_04315	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA650_04375	ENOG4107TY6	Acylneuraminate cytidylyltransferase
AA650_04385	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AA650_04390	ENOG4105BZ1	(ABC) transporter
AA650_04395	ENOG4105C5E	polysaccharide biosynthesis protein
AA650_04425	ENOG4108IAJ	Nad-dependent epimerase dehydratase
AA650_04435	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AA650_04455	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
AA650_04465	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AA650_04475	ENOG4105CMQ	Chloride channel
AA650_04490	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AA650_04500	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AA650_04515	ENOG4105CEV	competence damage-inducible protein
AA650_04540	ENOG4105C31	Tryptophanyl-tRNA synthetase
AA650_04580	ENOG4105CUT	histidyl-tRNA synthetase
AA650_04605	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AA650_04610	ENOG4105C8U	phosphate abc transporter
AA650_04615	ENOG4105E2Z	phosphate ABC transporter (Permease
AA650_04620	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AA650_04625	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
AA650_04665	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AA650_04690	ENOG4105VFU	Rna-binding protein
AA650_04695	ENOG4108Y85	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
AA650_04710	ENOG4105C8S	subunit m
AA650_04730	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AA650_04745	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AA650_04765	ENOG4105DDQ	anthranilate synthase
AA650_04770	ENOG4105E8R	UPF0173 metal-dependent hydrolase
AA650_04780	ENOG4105BZU	Histidine kinase
AA650_04790	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AA650_04805	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AA650_04825	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AA650_04830	ENOG4108JB9	formate dehydrogenase
AA650_04985	ENOG4105DR5	peptidase
AA650_04995	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
AA650_05000	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AA650_05005	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA650_05010	ENOG4107YX3	NADH dehydrogenase subunit j
AA650_05015	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA650_05020	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AA650_05050	ENOG4105CJ1	ABC, transporter
AA650_05065	ENOG4105CBS	Chea signal transduction histidine kinase
AA650_05075	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AA650_05110	ENOG4105N7N	Pentapeptide repeat-containing protein
AA650_05115	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AA650_05120	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AA650_05130	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AA650_05140	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
AA650_05150	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
AA650_05170	ENOG4107XWB	Zinc finger, swim domain protein
AA650_05185	ENOG41080XM	UPF0145 protein
AA650_05200	ENOG4105CHH	sulfate transporter
AA650_05295	ENOG4105BZU	Histidine kinase
AA650_05350	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
AA650_05385	ENOG4105CIC	tryptophan-specific transport protein
AA650_05420	ENOG4105WCA	Ferredoxin
AA650_05445	ENOG4107T8T	UPF0173 metal-dependent hydrolase
AA650_05460	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
AA650_05465	ENOG4105CZX	twitching motility protein
AA650_05475	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
AA650_05480	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AA650_05485	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AA650_05495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_05500	ENOG4105BZU	Histidine kinase
AA650_05505	ENOG4105BZU	Histidine kinase
AA650_05525	ENOG4105DRS	transport system, permease
AA650_05545	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
AA650_05575	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AA650_05595	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AA650_05605	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA650_05620	ENOG4105C37	(CBS) domain
AA650_05640	ENOG4105XEV	csbD-like
AA650_05655	ENOG4105XEV	csbD-like
AA650_05660	ENOG4105T2N	Domain of unknown function (DUF2382)
AA650_05670	ENOG4105BZ1	(ABC) transporter
AA650_05685	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AA650_05790	ENOG4105D64	Mechanosensitive ion channel
AA650_05795	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AA650_05830	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AA650_05840	ENOG4105KZX	Pterin carbinolamine dehydratase
AA650_05855	ENOG4105CNW	domain protein
AA650_05860	ENOG4105CNW	domain protein
AA650_05865	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AA650_05870	ENOG4107QRP	cobalamin biosynthesis protein CobW
AA650_05920	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AA650_05935	ENOG4105I3K	Ferric uptake regulator, Fur family
AA650_05975	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_05980	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AA650_05985	ENOG4107U45	Cobalt transport protein
AA650_06060	ENOG4105EYW	Ion transport protein
AA650_06070	ENOG4107SC1	transglycosylase
AA650_06075	ENOG4105EWK	phytoene
AA650_06080	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_06120	ENOG4105CPC	Aldo Keto reductase
AA650_06180	ENOG41063C6	UPF0235 protein
AA650_06185	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AA650_06200	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AA650_06225	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AA650_06240	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AA650_06255	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
AA650_06260	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AA650_06270	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AA650_06285	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AA650_06290	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AA650_06330	ENOG4105BZU	Histidine kinase
AA650_06355	ENOG4105DHJ	ABC, transporter
AA650_06365	ENOG4105DCF	alanine dehydrogenase
AA650_06370	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AA650_06385	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AA650_06405	ENOG4108SHJ	s-layer protein
AA650_06415	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AA650_06425	ENOG4105CHV	Transcription elongation factor NusA
AA650_06430	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
AA650_06435	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AA650_06495	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AA650_06500	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AA650_06505	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AA650_06510	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AA650_06515	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AA650_06520	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AA650_06570	ENOG4108ZJ4	polysaccharide deacetylase
AA650_06575	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
AA650_06590	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AA650_06605	ENOG4105DQR	SNARE associated Golgi
AA650_06610	ENOG4105BZ1	(ABC) transporter
AA650_06670	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AA650_06675	ENOG41082HT	Binds the 23S rRNA (By similarity)
AA650_06680	ENOG4108UJD	30S ribosomal protein S9
AA650_06685	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AA650_06690	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AA650_06695	ENOG4108ZT0	50S ribosomal protein l17
AA650_06700	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AA650_06705	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AA650_06710	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AA650_06725	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AA650_06730	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AA650_06735	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AA650_06740	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AA650_06745	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AA650_06750	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AA650_06755	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AA650_06760	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AA650_06765	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AA650_06770	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AA650_06775	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AA650_06780	ENOG410848H	50s ribosomal protein l29
AA650_06785	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AA650_06790	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AA650_06795	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AA650_06800	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AA650_06805	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AA650_06810	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AA650_06815	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AA650_06820	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AA650_06825	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
AA650_06875	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AA650_06885	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AA650_06930	ENOG4108ZF3	Phosphatase
AA650_06965	ENOG4105CIK	Amidinotransferase
AA650_06990	ENOG4105D3R	alkyl hydroperoxide reductase
AA650_06995	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AA650_07000	ENOG4105EWN	Heme oxygenase
AA650_07010	ENOG4105PGM	cation diffusion facilitator family transporter
AA650_07015	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AA650_07050	ENOG4105BZU	Histidine kinase
AA650_07060	ENOG4105PGM	cation diffusion facilitator family transporter
AA650_07085	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AA650_07090	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AA650_07115	ENOG4105J0U	photosystem II
AA650_07120	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AA650_07165	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AA650_07180	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AA650_07185	ENOG4105C8M	UPF0272 protein
AA650_07195	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AA650_07205	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_07220	ENOG4105BZM	domain protein
AA650_07240	ENOG410890F	Dynamin family
AA650_07255	ENOG41086DT	Membrane protein of unknown function
AA650_07275	ENOG4105TQG	cytochrome C, class I
AA650_07295	ENOG4107QRG	dna polymerase iii
AA650_07300	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AA650_07315	ENOG4105D6V	phycocyanin beta subunit
AA650_07320	ENOG4108SDR	phycocyanin, alpha subunit
AA650_07325	ENOG4108MZQ	phycobilisome linker polypeptide
AA650_07335	ENOG41078GB	pbs lyase
AA650_07340	ENOG4108V9J	phycocyanobilin lyase
AA650_07345	ENOG4106BTU	phycobilisome rod-core linker polypeptide
AA650_07350	ENOG4106BTU	phycobilisome rod-core linker polypeptide
AA650_07360	ENOG4106Q05	Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes (By similarity)
AA650_07370	ENOG4105E0X	reductase
AA650_07375	ENOG4105E7A	Glutamine amidotransferase
AA650_07380	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AA650_07385	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AA650_07390	ENOG4107Z6A	sulfate abc transporter permease
AA650_07405	ENOG4106H3A	restriction
AA650_07415	ENOG4105C9M	aspartyl-trna synthetase
AA650_07425	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
AA650_07435	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AA650_07450	ENOG4105CH5	extracellular solute-binding protein, family 7
AA650_07460	ENOG4105E6M	Sulphatase-modifying factor protein
AA650_07475	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA650_07480	ENOG4108U7W	acetyltransferase
AA650_07485	ENOG4105NP4	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
AA650_07510	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AA650_07515	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AA650_07520	ENOG4107R73	Mate efflux family protein
AA650_07525	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AA650_07585	ENOG4105C6E	dna polymerase iii
AA650_07625	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AA650_07630	ENOG410848W	30S ribosomal protein S21
AA650_07635	ENOG4105D85	methylase
AA650_07645	ENOG41080E3	single-stranded DNA-binding protein
AA650_07650	ENOG4105DFF	Rod shape-determining protein mreb
AA650_07665	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AA650_07680	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AA650_07685	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
AA650_07690	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AA650_07725	ENOG4105KC4	UPF0296 protein
AA650_07730	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AA650_07735	ENOG4108W6I	photosystem I reaction center protein subunit XI
AA650_07740	ENOG4108VV8	photosystem i
AA650_07745	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AA650_07750	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AA650_07775	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
AA650_07780	ENOG4105CEY	Amp-dependent synthetase and ligase
AA650_07795	ENOG4105E4F	Isochorismate synthase
AA650_07800	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AA650_07890	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
AA650_07900	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AA650_07920	ENOG4105EWK	phytoene
AA650_07930	ENOG4105DXN	mazG family
AA650_07975	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AA650_07990	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
AA650_07995	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AA650_08010	ENOG4105E66	phosphoriboisomerase A
AA650_08030	ENOG4105CZN	Potassium uptake protein
AA650_08035	ENOG4107ZYR	domain protein
AA650_08045	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AA650_08055	ENOG41083KH	UPF0102 protein
AA650_08075	ENOG4105C9B	Cysteine desulfurase
AA650_08095	ENOG4105K63	Thioredoxin
AA650_08125	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
AA650_08150	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AA650_08185	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AA650_08190	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AA650_08195	ENOG4106855	Competence protein
AA650_08200	ENOG4106855	Competence protein
AA650_08235	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AA650_08240	ENOG4105D9R	oxidoreductase
AA650_08250	ENOG4108UW5	maltose o-acetyltransferase
AA650_08255	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AA650_08260	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AA650_08345	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_08355	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_08380	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
AA650_08385	ENOG4105T2N	Domain of unknown function (DUF2382)
AA650_08415	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AA650_08450	ENOG41071TK	Uncharacterised protein family (UPF0150)
AA650_08455	ENOG4105YAJ	CopG Arc MetJ
AA650_08480	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AA650_08515	ENOG4105JZI	cytochrome P450
AA650_08520	ENOG4105EWK	phytoene
AA650_08540	ENOG4105CP7	Triose-phosphate isomerase
AA650_08555	ENOG4105DAY	polysaccharide export protein
AA650_08565	ENOG4105DA5	(ABC) transporter
AA650_08570	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AA650_08580	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AA650_08585	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
AA650_08590	ENOG4108R0D	protein with myosin-like
AA650_08630	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA650_08640	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AA650_08645	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AA650_08685	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AA650_08695	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AA650_08700	ENOG4108JQC	penicillin-binding protein 1A
AA650_08730	ENOG41082NI	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AA650_08735	ENOG4108WZM	domain protein
AA650_08750	ENOG4106FN3	tellurium resistance protein
AA650_08755	ENOG4105YVZ	photosystem II
AA650_08765	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AA650_08780	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_08820	ENOG4105E2X	shikimate dehydrogenase
AA650_08835	ENOG4105C7B	Threonine dehydratase
AA650_08840	ENOG4108IJ6	ABC transporter
AA650_08895	ENOG4108SHN	Glycosyl transferase, family 2
AA650_08910	ENOG4105BZ1	(ABC) transporter
AA650_08935	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AA650_08955	ENOG4105D9R	oxidoreductase
AA650_08965	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AA650_08970	ENOG4107YJ4	chain length determinant protein
AA650_08975	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
AA650_09020	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
AA650_09070	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
AA650_09095	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_09115	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AA650_09120	ENOG4105W8H	transhydrogenase (subunit alpha
AA650_09125	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AA650_09135	ENOG41082ZZ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AA650_09145	ENOG4107RIX	inner membrane protein translocase component YidC
AA650_09160	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
AA650_09170	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AA650_09175	ENOG4105CH7	arginosuccinase
AA650_09185	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
AA650_09190	ENOG4108J59	Extracellular solute-binding protein, family 5
AA650_09205	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AA650_09220	ENOG4105DDG	Cyanophycinase
AA650_09225	ENOG4107RRY	Cyanophycin synthetase
AA650_09260	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AA650_09280	ENOG4106IPI	cyclase, family
AA650_09320	ENOG4107T8Q	Glycosyl transferase (Group 1
AA650_09325	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AA650_09345	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AA650_09350	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AA650_09355	ENOG4107TS3	membrane protein, TerC
AA650_09365	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_09380	ENOG4105EYH	Exonuclease
AA650_09400	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_09410	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AA650_09465	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AA650_09480	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA650_09485	ENOG4105CJ3	phosphate transporter
AA650_09495	ENOG4108K9Q	Controls heterocyst differentiation. Has both a protease and a DNA-binding activity (By similarity)
AA650_09505	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AA650_09510	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AA650_09520	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AA650_09525	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_09580	ENOG4105C01	Dihydroxy-acid dehydratase
AA650_09605	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AA650_09620	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AA650_09635	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AA650_09645	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AA650_09665	ENOG4107RNB	anthranilate phosphoribosyltransferase
AA650_09715	ENOG4105G6Z	alkaline phosphatase
AA650_09745	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AA650_09770	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AA650_09780	ENOG4105CQC	Prephenate dehydratase
AA650_09790	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA650_09795	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AA650_09810	ENOG4105D06	uba thif-type nad fad binding protein
AA650_09825	ENOG4105DRS	transport system, permease
AA650_09840	ENOG4105CP2	von willebrand factor, type a
AA650_09855	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
AA650_09865	ENOG4105DWF	phosphomethylpyrimidine kinase
AA650_09875	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA650_09900	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AA650_09935	ENOG4105EHU	Circadian clock protein KaiC
AA650_09940	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
AA650_09945	ENOG4108WXF	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation
AA650_09950	ENOG4105BZU	Histidine kinase
AA650_09955	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AA650_09975	ENOG4105CNG	UPF0061 protein
AA650_10005	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_10010	ENOG4105WN5	stage II sporulation protein
AA650_10045	ENOG4105BZU	Histidine kinase
AA650_10050	ENOG4105D9U	N-acetyltransferase
AA650_10055	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AA650_10075	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AA650_10080	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AA650_10095	ENOG4105D49	3-dehydroquinate synthase
AA650_10120	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AA650_10145	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AA650_10150	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA650_10155	ENOG4108IV0	ABC, transporter
AA650_10185	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AA650_10205	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AA650_10235	ENOG4105ETX	regulatoR
AA650_10270	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA650_10290	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AA650_10330	ENOG4105C0W	non-ribosomal peptide synthetase
AA650_10350	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA650_10355	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AA650_10360	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AA650_10365	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AA650_10380	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA650_10430	ENOG4108JJB	ABC transporter
AA650_10435	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AA650_10455	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA650_10475	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AA650_10495	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_10505	ENOG4105NI8	Cytosine-specific methyltransferase
AA650_10560	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AA650_10615	ENOG4107RAQ	aminopeptidase
AA650_10640	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_10650	ENOG4105C8Y	Acetylornithine aminotransferase
AA650_10675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_10680	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AA650_10705	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AA650_10710	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AA650_10715	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
AA650_10725	ENOG4105D9P	serine threonine protein kinase
AA650_10735	ENOG4105DTQ	mandelate racemase muconate lactonizing
AA650_10765	ENOG41063NY	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AA650_10770	ENOG4107WDG	serine threonine protein kinase
AA650_10775	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
AA650_10820	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AA650_10825	ENOG4106F1P	AAA ATPase, central domain protein
AA650_10840	ENOG4105WH1	Two component transcriptional regulator luxr family
AA650_10865	ENOG4108IJ8	ABC transporter
AA650_10900	ENOG41067HS	methyltransferase
AA650_10905	ENOG4105D8X	mechanosensitive ion channel
AA650_10910	ENOG4105D64	Mechanosensitive ion channel
AA650_10920	ENOG4105BZU	Histidine kinase
AA650_10950	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AA650_10955	ENOG4108DIF	synthase (EC 4.2.1.75)
AA650_10960	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AA650_10965	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_10975	ENOG4105D7V	transposase
AA650_10980	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
AA650_10990	ENOG4105IDI	abc transporter atp-binding protein
AA650_11005	ENOG4105CBS	Chea signal transduction histidine kinase
AA650_11020	ENOG4105M3Z	response regulator
AA650_11025	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA650_11030	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AA650_11045	ENOG4105C0X	amino acid
AA650_11075	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AA650_11080	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AA650_11085	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AA650_11095	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AA650_11155	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA650_11170	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AA650_11175	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AA650_11235	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
AA650_11240	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AA650_11250	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
AA650_11255	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AA650_11260	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AA650_11290	ENOG4106KE4	Dehydrogenase
AA650_11310	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AA650_11335	ENOG4107P5I	polyketide synthase
AA650_11365	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AA650_11375	ENOG4105D3G	Pseudouridine synthase
AA650_11390	ENOG4105C0D	helicase
AA650_11410	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
AA650_11445	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AA650_11450	ENOG4105CQB	FAD linked oxidase domain protein
AA650_11455	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AA650_11475	ENOG4105DBI	uridine monophosphokinase
AA650_11480	ENOG4105W5Q	DNA repair protein (RadC
AA650_11510	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AA650_11585	ENOG4105Q84	sucrose synthase
AA650_11595	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
AA650_11610	ENOG4107ZHV	Transcriptional regulator
AA650_11620	ENOG4108IUZ	ABC transporter
AA650_11645	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AA650_11705	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA650_11710	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
AA650_11720	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AA650_11725	ENOG4105D7T	ABC transporter
AA650_11740	ENOG4105I5W	Transporter
AA650_11795	ENOG4105CKI	cobalamin synthesis protein
AA650_11805	ENOG4105C8S	subunit m
AA650_11810	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AA650_11815	ENOG4105E2Z	phosphate ABC transporter (Permease
AA650_11820	ENOG4105C8U	phosphate abc transporter
AA650_11825	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AA650_11840	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AA650_11845	ENOG4108JQC	penicillin-binding protein 1A
AA650_11850	ENOG4107WDG	serine threonine protein kinase
AA650_11915	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AA650_11930	ENOG4105DC8	reductase
AA650_11935	ENOG4105KHC	sulfurtransferase
AA650_11940	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AA650_11945	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AA650_11950	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AA650_11955	ENOG41081F0	Precorrin-8x methylmutase
AA650_11960	ENOG4105DVK	Precorrin-2 c20-methyltransferase
AA650_11975	ENOG4108NWW	ferritin dps family protein
AA650_11985	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AA650_11990	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA650_12000	ENOG4105M6F	mutator MutT protein
AA650_12015	ENOG4105CDA	abc transporter atp-binding protein
AA650_12020	ENOG4105DRP	amino acid AbC transporter
AA650_12025	ENOG4105EZ7	amino acid ABC transporter
AA650_12030	ENOG4107QXX	ABC transporter
AA650_12040	ENOG4108Z6B	deaminase
AA650_12050	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AA650_12085	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
AA650_12095	ENOG4105C19	ABC transporter
AA650_12125	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
AA650_12145	ENOG4105C1V	Peptidase, M16
AA650_12220	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AA650_12245	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AA650_12255	ENOG4105CE4	GlcNAc 6-P deacetylase
AA650_12260	ENOG4105K6T	rare lipoprotein A
AA650_12265	ENOG4105CAT	Cytidine monophosphate kinase
AA650_12270	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AA650_12275	ENOG4107QJE	Chromosome Partitioning Protein
AA650_12280	ENOG4105CNU	cell division protein FtsK
AA650_12295	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
AA650_12320	ENOG4105BZU	Histidine kinase
AA650_12325	ENOG4105ETX	regulatoR
AA650_12330	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AA650_12415	ENOG4105D9N	nucleoside
AA650_12435	ENOG4108KGH	TRANSCRIPTIONal
AA650_12450	ENOG4105BZF	Glycosyl transferase (Group 1
AA650_12480	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AA650_12485	ENOG4107WDG	serine threonine protein kinase
AA650_12525	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AA650_12530	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AA650_12540	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AA650_12555	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AA650_12560	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AA650_12570	ENOG4108TNP	
AA650_12590	ENOG41090HT	Inherit from COG: transposase
AA650_12640	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AA650_12650	ENOG4108062	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AA650_12655	ENOG4107WDG	serine threonine protein kinase
AA650_12660	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AA650_12695	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_12700	ENOG4105D82	Glutamate dehydrogenase
AA650_12760	ENOG4108PJD	permease
AA650_12780	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AA650_12815	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AA650_12825	ENOG4105D6J	arsenicaL-resistance protein
AA650_12830	ENOG4105EGD	dinuclear metal center protein, YbgI family
AA650_12855	ENOG4105K63	Thioredoxin
AA650_12870	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AA650_12875	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
AA650_12920	ENOG4105EWU	Squalene--hopene cyclase
AA650_13000	ENOG4108Z0R	Transferase
AA650_13010	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AA650_13045	ENOG4105GVR	general secretion pathway protein D
AA650_13050	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AA650_13100	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AA650_13105	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AA650_13110	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
AA650_13230	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AA650_13240	ENOG4105CA3	membrane-bound lytic murein transglycosylase
AA650_13250	ENOG4105CVJ	phosphoglycerate mutase
AA650_13265	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AA650_13280	ENOG4108KMV	Glycosyl transferase (Group 1
AA650_13290	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
AA650_13305	ENOG4105C1J	atp-dependent rna helicase
AA650_13315	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AA650_13335	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AA650_13340	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
AA650_13345	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
AA650_13385	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AA650_13390	ENOG4105C72	UPF0176 protein
AA650_13410	ENOG4105CPF	Cell wall formation (By similarity)
AA650_13420	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AA650_13435	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AA650_13445	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AA650_13480	ENOG4108KQJ	Type 11 methyltransferase
AA650_13495	ENOG4105D05	Receptor
AA650_13500	ENOG4105CFP	Peptidase U32
AA650_13545	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AA650_13550	ENOG4105DKQ	ROK family
AA650_13555	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AA650_13565	ENOG4105DZP	Membrane-associated zinc metalloprotease
AA650_13610	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AA650_13615	ENOG4105MKQ	Monovalent cation H antiporter subunit C
AA650_13620	ENOG4105CXN	decarboxylase
AA650_13650	ENOG410901P	UPF0249 protein
AA650_13700	ENOG4105IBP	Cyclic peptide transporter
AA650_13730	ENOG4105C12	Phosphoribosylglycinamide synthetase
AA650_13735	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AA650_13765	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA650_13780	ENOG4108UV1	cellular component movement
AA650_13800	ENOG41087PP	glycosyltransferase MGT family
AA650_13820	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
AA650_13825	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AA650_13845	ENOG4106AG1	Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity)
AA650_13855	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AA650_13915	ENOG4105WH1	Two component transcriptional regulator luxr family
AA650_13925	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AA650_13930	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA650_13945	ENOG4105C5R	Aminotransferase
AA650_13955	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AA650_13960	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
AA650_13975	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AA650_13990	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_14000	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_14005	ENOG4105D7V	transposase
AA650_14020	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
AA650_14025	ENOG4105MSA	Photosystem II reaction center W protein
AA650_14030	ENOG4105G6Z	alkaline phosphatase
AA650_14040	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AA650_14050	ENOG4105CEY	Amp-dependent synthetase and ligase
AA650_14065	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AA650_14100	ENOG4107R73	Mate efflux family protein
AA650_14105	ENOG4105CHM	Aminotransferase
AA650_14115	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AA650_14140	ENOG4105CDY	transcriptional regulatory protein
AA650_14145	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AA650_14150	ENOG4107TVC	Glycosyl transferase, family 2
AA650_14155	ENOG4105EDW	glycosyl transferase, family 39
AA650_14215	ENOG410667J	hydrolase
AA650_14265	ENOG4105C0H	protease
AA650_14310	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AA650_14330	ENOG4105BZU	Histidine kinase
AA650_14365	ENOG4105C0D	helicase
AA650_14375	ENOG4105EWK	phytoene
AA650_14380	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AA650_14390	ENOG4108VIA	integral membrane protein
AA650_14425	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AA650_14430	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AA650_14440	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AA650_14445	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AA650_14465	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AA650_14495	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
AA650_14540	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
AA650_14580	ENOG4105VTW	prevent-host-death family
AA650_14585	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AA650_14595	ENOG4105D6A	Electron transport complex
AA650_14610	ENOG4105C8S	subunit m
AA650_14620	ENOG4105D65	subunit l
AA650_14630	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
AA650_14635	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AA650_14640	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
AA650_14655	ENOG4105C0D	helicase
AA650_14665	ENOG4105DUM	transcriptional regulator, lysR family
AA650_14690	ENOG4108V5V	Serine Threonine protein kinase
AA650_14740	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AA650_14765	ENOG4105C59	p-type ATPase
AA650_14775	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AA650_14805	ENOG4105CPQ	Dehydrogenase
AA650_14810	ENOG4105CGK	Exodeoxyribonuclease III
AA650_14845	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
AA650_14880	ENOG4105C5H	ABC transporter
AA650_14905	ENOG4105CD8	aminopeptidase N
AA650_14930	ENOG4105CB5	ATP-dependent DNA helicase recG
AA650_14975	ENOG4105X25	
AA650_15005	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
AA650_15050	ENOG410906A	Beta-Ig-H3 fasciclin
AA650_15055	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AA650_15075	ENOG4105K63	Thioredoxin
AA650_15080	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AA650_15120	ENOG4105D65	subunit l
AA650_15130	ENOG4105C8S	subunit m
AA650_15140	ENOG4105ND9	Nitrogenase-associated protein
AA650_15200	ENOG410801B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AA650_15210	ENOG4105WQ3	Rna-binding protein
AA650_15265	ENOG4105K70	DNA-binding protein
AA650_15270	ENOG4107QZB	decarboxylase
AA650_15290	ENOG4107R73	Mate efflux family protein
AA650_15295	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AA650_15340	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AA650_15350	ENOG4108IAJ	Nad-dependent epimerase dehydratase
AA650_15370	ENOG4105CHR	reductase
AA650_15375	ENOG4105TRI	Hydrolase
AA650_15395	ENOG4105XA0	heptosyltransferase ii
AA650_15400	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AA650_15470	ENOG4105C8H	hydrogenase maturation protein Hypf
AA650_15480	ENOG4105CQS	hydrogenase expression formation protein HypD
AA650_15490	ENOG4105C45	hydrogenase expression formation protein (HypE)
AA650_15495	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AA650_15505	ENOG4108YRB	methyltransferase
AA650_15615	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AA650_15620	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AA650_15630	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AA650_15690	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AA650_15735	ENOG4105CHM	Aminotransferase
AA650_15740	ENOG4105N6Y	Thioredoxin
AA650_15780	ENOG4108IPT	Naphthoate synthase
AA650_15785	ENOG4107QRI	Phosphoketolase
AA650_15840	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AA650_15850	ENOG4107QV2	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AA650_15880	ENOG4105C59	p-type ATPase
AA650_15900	ENOG4105DUM	transcriptional regulator, lysR family
AA650_15910	ENOG4105K63	Thioredoxin
AA650_15950	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
AA650_15960	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AA650_15970	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AA650_15990	ENOG4105XCI	PucC protein
AA650_16025	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AA650_16030	ENOG4105E2K	Glycosyl transferase (Group 1
AA650_16035	ENOG4105D38	putrescine abc transporter
AA650_16060	ENOG41063JG	Transcriptional regulator
AA650_16085	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AA650_16090	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AA650_16195	ENOG4107RCI	amp-dependent synthetase and ligase
AA650_16235	ENOG4105VT3	DNA binding domain protein, excisionase family
AA650_16315	ENOG4105GIM	CRISPR-associated protein cas6
AA650_16375	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AA650_16410	ENOG4107QJE	Chromosome Partitioning Protein
AA650_16415	ENOG4105CPN	adenine deaminase
AA650_16455	ENOG4105FA0	parb-like partition protein
AA650_16460	ENOG4107QJE	Chromosome Partitioning Protein
AA650_16515	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_16600	ENOG4105ESV	Glycosyl transferase, family 4
AA650_16605	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AA650_16665	ENOG4105C3G	gtp-binding protein
AA650_16680	ENOG4105D7V	transposase
AA650_16690	ENOG4105D7V	transposase
AA650_16700	ENOG4105CN1	protease
AA650_16705	ENOG4105E6M	Sulphatase-modifying factor protein
AA650_16715	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AA650_16725	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AA650_16730	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AA650_16750	ENOG4108159	Pfam:UPF0005
AA650_16775	ENOG4105CXI	aluminum resistance protein
AA650_16785	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
AA650_16845	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AA650_16855	ENOG4105DN3	alpha-2-macroglobulin domain protein
AA650_16860	ENOG4108JQB	penicillin-binding protein 1C
AA650_16885	ENOG4107Z8V	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AA650_16895	ENOG4105VFU	Rna-binding protein
AA650_16900	ENOG4105VFU	Rna-binding protein
AA650_16915	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AA650_16925	ENOG4107RFW	hydrolase family 57
AA650_16935	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AA650_16945	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA650_16950	ENOG4105CFG	Acts as a chaperone (By similarity)
AA650_16965	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AA650_16970	ENOG4107QHF	type ii secretion system protein e
AA650_16975	ENOG4105CZX	twitching motility protein
AA650_17005	ENOG4105CD2	stage iii sporulation protein aa
AA650_17045	ENOG4105CD3	dihydroorotase
AA650_17050	ENOG4105C0H	protease
AA650_17065	ENOG4105K8N	protein family UPF0079, ATPase
AA650_17075	ENOG4105CHW	UPF0052 protein
AA650_17080	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AA650_17110	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AA650_17160	ENOG4105CW7	secretion protein, HlyD family
AA650_17190	ENOG4105JFG	SpoIID LytB domain protein
AA650_17195	ENOG4107YJ4	chain length determinant protein
AA650_17235	ENOG4107R73	Mate efflux family protein
AA650_17270	ENOG4108DJF	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AA650_17280	ENOG4107QI6	Cysteine desulfurase
AA650_17350	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AA650_17390	ENOG4105CBT	Fructose-1,6-bisphosphatase
AA650_17395	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AA650_17415	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AA650_17420	ENOG4105VFU	Rna-binding protein
AA650_17430	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
AA650_17435	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AA650_17445	ENOG4108UK5	Transposase
AA650_17505	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AA650_17530	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AA650_17540	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AA650_17560	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
AA650_17580	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AA650_17610	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA650_17620	ENOG4105E2K	Glycosyl transferase (Group 1
AA650_17625	ENOG4108IJ9	(ABC) transporter
AA650_17645	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AA650_17700	ENOG4108IJ0	Aspartate ammonia-lyase
AA650_17720	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA650_17760	ENOG4105K64	Glycosyl transferase, family 2
AA650_17770	ENOG4105EY8	ABC transporter
AA650_17800	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
AA650_17805	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
AA650_17835	ENOG4105F0N	pyrophosphate phospho-hydrolase
AA650_17840	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AA650_17845	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AA650_17995	ENOG4105DJZ	UPF0182 protein
AA650_18000	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AA650_18005	ENOG4105BZU	Histidine kinase
AA650_18010	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA650_18015	ENOG4105CSR	polyphosphate kinase 2
AA650_18020	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA650_18035	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AA650_18040	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AA650_18060	ENOG4105G5N	sensor protein
AA650_18080	ENOG4108JJA	ABC, transporter
AA650_18100	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AA650_18110	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AA650_18140	ENOG4105CJ1	ABC, transporter
AA650_18145	ENOG4105D0S	secretion protein (HlyD
AA650_18160	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AA650_18165	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AA650_18170	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AA650_18180	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
AA650_18185	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AA650_18210	ENOG41089UC	methyltransferase, type 11
AA650_18225	ENOG4105E6M	Sulphatase-modifying factor protein
AA650_18240	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AA650_18250	ENOG4108Z03	MAF-like protein
AA650_18265	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
AA650_18275	ENOG41071TK	Uncharacterised protein family (UPF0150)
AA650_18340	ENOG4105V5Z	Iron-sulfur cluster assembly accessory protein
AA650_18345	ENOG41081QJ	UBA THIF-type NAD FAD binding
AA650_18350	ENOG4105R88	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
AA650_18355	ENOG4105X87	nitrogen fixation
AA650_18360	ENOG4108VQE	nitrogen fixation protein
AA650_18365	ENOG4108UR2	Nitrogen fixation protein NifX
AA650_18370	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
AA650_18375	ENOG4105D0B	Nitrogenase protein alpha chain
AA650_18380	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
AA650_18455	ENOG4105EMU	Dehydrogenase
AA650_18465	ENOG4108S59	
AA650_18470	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AA650_18550	ENOG4105CNF	WD-40 repeat protein
AA650_18560	ENOG4105D0B	Nitrogenase protein alpha chain
AA650_18615	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
AA650_18660	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA650_18705	ENOG4105CBG	Sulfatase
AA650_18710	ENOG4105E6M	Sulphatase-modifying factor protein
AA650_18715	ENOG4108RXX	maleylacetoacetate isomerase
AA650_18755	ENOG4105BZ1	(ABC) transporter
AA650_18760	ENOG4105CPC	Aldo Keto reductase
AA650_18775	ENOG4105CPU	Monooxygenase
AA650_18780	ENOG4105CPU	Monooxygenase
AA650_18815	ENOG4107XGZ	Hydrolase
AA650_18830	ENOG4107MKT	Stringent starvation protein a
AA650_18920	ENOG4105DWV	Homoserine O-trans-acetylase
AA650_18925	ENOG4108IQK	o-acetylhomoserine
AA650_18930	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
AA650_18935	ENOG4105GVF	(ABC) transporter
AA650_18940	ENOG4105EMU	Dehydrogenase
AA650_18950	ENOG4105GVF	(ABC) transporter
AA650_18955	ENOG4108302	MgtC SapB transporter
AA650_18980	ENOG4105C5I	Dehydrogenase
AA650_18990	ENOG4108IYU	L-aspartate oxidase
AA650_18995	ENOG4105CHR	reductase
AA650_19020	ENOG4105CPC	Aldo Keto reductase
AA650_19025	ENOG4108PWY	Carbohydrate-selective porin OprB
AA650_19030	ENOG4108DBC	nitroreductase
AA650_19040	ENOG4105E2Y	ABC, transporter
AA650_19050	ENOG4105E2B	Taurine dioxygenase
AA650_19055	ENOG4105GVF	(ABC) transporter
AA650_19060	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AA650_19065	ENOG4105FBW	Monooxygenase
AA650_19070	ENOG4108UZX	fmn reductase
AA650_19095	ENOG4107TSN	permease
AA650_19120	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
AA650_19125	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
AA650_19180	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
AA650_19185	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
AA650_19190	ENOG4105C3J	Cysteine desulfurase
AA650_19195	ENOG4108AC1	4fe-4s ferredoxin, iron-sulfur binding
AA650_19225	ENOG4107S73	homocitrate synthase
AA650_19255	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AA650_19285	ENOG4107R73	Mate efflux family protein
AA650_19290	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AA650_19295	ENOG4105DVW	rieske (2Fe-2S)
AA650_19315	ENOG4108JA1	polyketide synthase
AA650_19315	ENOG4108JA1	polyketide synthase
AA650_19325	ENOG4108JA1	polyketide synthase
AA650_19360	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AA650_19365	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AA650_19385	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AA650_19390	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AA650_19395	ENOG4105DFU	Cell wall formation (By similarity)
AA650_19400	ENOG4105D4A	Cell wall formation (By similarity)
AA650_19405	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AA650_19420	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_19455	ENOG4105BZU	Histidine kinase
AA650_19480	ENOG4105J0C	
AA650_19485	ENOG4108RMU	ferritin dps family protein
AA650_19490	ENOG4105E0R	Deoxyhypusine synthase
AA650_19500	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AA650_19510	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA650_19540	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
AA650_19565	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
AA650_19590	ENOG4105C8B	TIGR00159 family
AA650_19595	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AA650_19630	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AA650_19665	ENOG4108K7V	UPF0284 protein
AA650_19705	ENOG4108TCG	allophycocyanin beta subunit
AA650_19720	ENOG4105CPQ	Dehydrogenase
AA650_19730	ENOG4105VT3	DNA binding domain protein, excisionase family
AA650_19795	ENOG4105C8T	Leucyl-tRNA synthetase
AA650_19800	ENOG4105JZI	cytochrome P450
AA650_19815	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AA650_19830	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AA650_19835	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AA650_19860	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_19900	ENOG4105CQR	helicase
AA650_19970	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
AA650_19985	ENOG4105C1V	Peptidase, M16
AA650_20045	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AA650_20070	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AA650_20080	ENOG4105CPC	Aldo Keto reductase
AA650_20090	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AA650_20105	ENOG4108SHJ	s-layer protein
AA650_20120	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AA650_20260	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AA650_20300	ENOG4105D0M	Protease HtpX homolog
AA650_20305	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AA650_20325	ENOG4107EFQ	arachidonate 15-lipoxygenase
AA650_20330	ENOG4105C5H	ABC transporter
AA650_20340	ENOG4105BZ1	(ABC) transporter
AA650_20355	ENOG4108M24	von Willebrand factor, type A
AA650_20410	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
AA650_20455	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AA650_20470	ENOG4108YZN	class I peptide chain release factor
AA650_20490	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AA650_20525	ENOG4105EYH	Exonuclease
AA650_20540	ENOG4105EYM	Major Facilitator superfamily
AA650_20570	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AA650_20585	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
AA650_20590	ENOG4108IYU	L-aspartate oxidase
AA650_20625	ENOG4108IYU	L-aspartate oxidase
AA650_20630	ENOG4105CVB	Vitamin K epoxide reductase
AA650_20640	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AA650_20680	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AA650_20685	ENOG41071TK	Uncharacterised protein family (UPF0150)
AA650_20760	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AA650_20765	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AA650_20770	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA650_20775	ENOG4107XWZ	ferric uptake regulator
AA650_20780	ENOG4105F0V	Cell wall hydrolase
AA650_20785	ENOG4105CTK	cobaltochelatase, cobn subunit
AA650_20820	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AA650_20900	ENOG4105CND	Glycosyl transferase, family 2
AA650_20905	ENOG4105CD5	CoA-binding domain protein
AA650_20930	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA650_20945	ENOG4107QIZ	NADH dehydrogenase
AA650_20975	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AA650_20985	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AA650_21015	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AA650_21035	ENOG4107RIQ	Sulfate adenylate transferase
AA650_21070	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AA650_21090	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AA650_21105	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AA650_21110	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AA650_21120	ENOG4105CKI	cobalamin synthesis protein
AA650_21125	ENOG4105C8N	cysteinyl-tRNA synthetase
AA650_21140	ENOG4105M3Z	response regulator
AA650_21145	ENOG4105BZU	Histidine kinase
AA650_21145	ENOG4105BZU	Histidine kinase
AA650_21150	ENOG4105CQB	FAD linked oxidase domain protein
AA650_21155	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA650_21170	ENOG4105EMU	Dehydrogenase
AA650_21175	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AA650_21180	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AA650_21190	ENOG4108E2B	had-superfamily hydrolase, subfamily iib
AA650_21245	ENOG41060D5	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AA650_21295	ENOG4105BZA	Phosphoglycerate kinase
AA650_21305	ENOG4107SGM	protein serine threonine phosphatase
AA650_21335	ENOG4108JYK	Dehydrogenase
AA650_21390	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AA650_21410	ENOG4105C26	Dehydrogenase
AA650_21420	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AA650_21425	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AA650_21495	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AA650_21520	ENOG4108NVR	Methyl-accepting chemotaxis
AA650_21530	ENOG4105CBS	Chea signal transduction histidine kinase
AA650_21530	ENOG4105CBS	Chea signal transduction histidine kinase
AA650_21545	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AA650_21550	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_21565	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA650_21620	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_21655	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AA650_21705	ENOG4108R6K	riboflavin synthase, subunit alpha
AA650_21715	ENOG41063SB	peptidase
AA650_21720	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AA650_21745	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
AA650_21750	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AA650_21760	ENOG4105D7Z	glutathione synthase
AA650_21770	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AA650_21785	ENOG4105CPJ	photosystem II manganese-stabilizing
AA650_21790	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA650_21810	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
AA650_21815	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
AA650_21820	ENOG410828V	rubredoxin
AA650_21825	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AA650_21830	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA650_21835	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AA650_21840	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AA650_21875	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AA650_21895	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
AA650_21915	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
AA650_22000	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AA650_22050	ENOG4105D7K	pfkb domain protein
AA650_22055	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AA650_22075	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AA650_22090	ENOG4105CEC	DNA methylase N-4 N-6
AA650_22105	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AA650_22115	ENOG4105DHP	deoxycytidine triphosphate deaminase
AA650_22150	ENOG4105CHM	Aminotransferase
AA650_22165	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
AA650_22170	ENOG4105DF7	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AA650_22195	ENOG4108VPT	UPF0234 protein
AA650_22200	ENOG4105CYM	Glutathione S-transferase
AA650_22230	ENOG4107S5T	Carbohydrate kinase
AA650_22275	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AA650_22285	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AA650_22290	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AA650_22295	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AA650_22300	ENOG4107QPR	SAICAR synthetase
AA650_22315	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AA650_22330	ENOG4105C26	Dehydrogenase
AA650_22335	ENOG41068G9	50S ribosomal protein L32
AA650_22370	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AA650_22380	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AA650_22385	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AA650_22390	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AA650_22420	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_22490	ENOG4108JJA	ABC, transporter
AA650_22495	ENOG4105DKQ	ROK family
AA650_22530	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AA650_22535	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
AA650_22580	ENOG4107Z12	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AA650_22590	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AA650_22600	ENOG41068KF	Universal stress protein
AA650_22655	ENOG4105CPC	Aldo Keto reductase
AA650_22660	ENOG4107YU2	histidine triad (hIT) protein
AA650_22680	ENOG4105C0P	Mg chelatase subunit ChlI
AA650_22685	ENOG4108I5U	Uridine phosphorylase
AA650_22705	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AA650_22715	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AA650_22725	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AA650_22775	ENOG41067D0	Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of toxin RelE2
AA650_22790	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AA650_22795	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AA650_22810	ENOG4105CJN	penicillin-binding protein
AA650_22840	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AA650_22870	ENOG4105D2N	Aldolase
AA650_22905	ENOG4105VUV	UPF0367 protein
AA650_22910	ENOG4108JJB	ABC transporter
AA650_22915	ENOG4108JQ6	ABC transporter
AA650_22925	ENOG4107TCE	N-acetyltransferase
AA650_22930	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AA650_22935	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
AA650_22940	ENOG4105C7W	Xanthine dehydrogenase
AA650_22945	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AA650_22950	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AA650_22970	ENOG4105F32	YngK protein
AA650_22990	ENOG4107ZBH	radical SAM domain protein
AA650_23010	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
AA650_23050	ENOG41085RW	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AA650_23065	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AA650_23080	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AA650_23085	ENOG4105K46	50S ribosomal protein l27
AA650_23105	ENOG4105D0M	Protease HtpX homolog
AA650_23110	ENOG4105WMR	Protein CrcB homolog
AA650_23145	ENOG4106F59	XRE family Transcriptional regulator
AA650_23150	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
AA650_23185	ENOG4105EUJ	GTP cyclohydrolase i
AA650_23190	ENOG4105CKI	cobalamin synthesis protein
AA650_23200	ENOG4105C22	threonyL-tRNA synthetase
AA650_23215	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_23230	ENOG4105D52	delta-aminolevulinic acid dehydratase
AA650_23235	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AA650_23250	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AA650_23255	ENOG4105EMN	RNA polymerase sigma factor
AA650_23310	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AA650_23315	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AA650_23320	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AA650_23335	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AA650_23340	ENOG4108YZ9	Urea amidohydrolase subunit gamma
AA650_23355	ENOG4105KI2	Urea amidohydrolase subunit beta
AA650_23360	ENOG4105CQM	Urea amidohydrolase subunit alpha
AA650_23365	ENOG4105DR5	peptidase
AA650_23375	ENOG4105CJ1	ABC, transporter
AA650_23385	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AA650_23405	ENOG4105C5S	asparaginyl-tRNA synthetase
AA650_23420	ENOG4107WDG	serine threonine protein kinase
AA650_23440	ENOG410890F	Dynamin family
AA650_23455	ENOG41082B1	30S ribosomal protein S16
AA650_23550	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AA650_23555	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AA650_23560	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AA650_23565	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AA650_23570	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AA650_23575	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AA650_23580	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
AA650_23585	ENOG4105PA3	atp synthase
AA650_23590	ENOG4107SWE	Methyltransferase
AA650_23625	ENOG4105E5Q	amino acid AbC transporter
AA650_23675	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA650_23680	ENOG4105IJJ	transcriptional regulator, crp fnr family
AA650_23730	ENOG4105CNF	WD-40 repeat protein
AA650_23735	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
AA650_23740	ENOG4105CPK	Glycosyl transferase (Group 1
AA650_23755	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
AA650_23760	ENOG41068XD	UPF0473 protein
AA650_23765	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AA650_23785	ENOG4105CN1	protease
AA650_23790	ENOG4108N5B	2-phosphosulfolactate phosphatase
AA650_23830	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AA650_23865	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA650_23870	ENOG4107S6X	Glycosyl transferase, family 2
AA650_23875	ENOG4105BZ1	(ABC) transporter
AA650_23890	ENOG4108QV3	biosynthesis protein
AA650_23895	ENOG4108TJN	glycosyl transferase group 1
AA650_23905	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AA650_23920	ENOG4107XZA	Glycosyl transferase family 2
AA650_23925	ENOG4107XZA	Glycosyl transferase family 2
AA650_23930	ENOG4105CMR	udp-glucose 4-epimerase
AA650_23935	ENOG4105D5U	fad dependent oxidoreductase
AA650_23940	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
AA650_23960	ENOG4108M24	von Willebrand factor, type A
AA650_24045	ENOG4105E0Y	RtcB Protein
AA650_24055	ENOG4105RYY	domain protein
AA650_24065	ENOG4105D52	delta-aminolevulinic acid dehydratase
AA650_24075	ENOG4105G5W	regulator Fur family
AA650_24125	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AA650_24130	ENOG4105C89	phosphohexose isomerase
AA650_24135	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AA650_24145	ENOG4105C0Z	ABC transporter
AA650_24155	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AA650_24215	ENOG4105DX0	Hemolysin A
AA650_24225	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AA650_24230	ENOG4105D0M	Protease HtpX homolog
AA650_24240	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA650_24250	ENOG4105F23	Fibronectin-binding protein
AA650_24260	ENOG4108PWY	Carbohydrate-selective porin OprB
AA650_24265	ENOG4105DSE	periplasmic solute binding protein
AA650_24270	ENOG4105FDK	ABC transporter
AA650_24275	ENOG4105FAV	ABC, transporter
AA650_24370	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AA650_24390	ENOG4105DGW	oligopeptidase A
AA650_24425	ENOG4105CTK	cobaltochelatase, cobn subunit
AA650_24550	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AA650_24570	ENOG4105VPX	protein, conserved in bacteria
AA650_24575	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AA650_24625	ENOG4105EKQ	RNA-directed DNA polymerase
AA650_24630	ENOG4105D7V	transposase
AA650_24650	ENOG4105D9R	oxidoreductase
AA650_24685	ENOG410811Q	Ferredoxin
AA650_24700	ENOG41084GC	stage II sporulation protein
AA650_24705	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_24725	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AA650_24740	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AA650_24810	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AA650_24825	ENOG4105WIA	photosystem II reaction center protein H
AA650_24830	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AA650_24835	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AA650_24840	ENOG410686T	photosystem II reaction center protein N
AA650_24845	ENOG4107R51	Glycosyl transferase, family 2
AA650_24850	ENOG4105CDH	Citrulline--aspartate ligase
AA650_24860	ENOG41082AN	stage II sporulation protein
AA650_24865	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AA650_24870	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
AA650_24875	ENOG410715G	filament integrity protein
AA650_24880	ENOG4105RRH	
AA650_24890	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AA650_24895	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AA650_24900	ENOG4108RS6	transposase
AA650_24905	ENOG4105C0H	protease
AA650_24915	ENOG4105C0H	protease
AA650_24920	ENOG4105DSE	periplasmic solute binding protein
AA650_24940	ENOG4105C4R	Atp-dependent dna helicase
AA650_24955	ENOG4105D9P	serine threonine protein kinase
AA650_24965	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
AA650_24970	ENOG4106MP8	UPF0754 membrane protein
AA650_24980	ENOG4105CNW	domain protein
AA650_24985	ENOG4105CNW	domain protein
AA650_24995	ENOG4105EXC	Acyl-transferase
AA650_25010	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_25040	ENOG41083EU	50s ribosomal protein l28
AA650_25095	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AA650_25115	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AA650_25135	ENOG4106H78	methyltransferase
AA650_25140	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AA650_25145	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
AA650_25160	ENOG4105CMR	udp-glucose 4-epimerase
AA650_25165	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA650_25170	ENOG4105D3Q	Sugar transferase
AA650_25175	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AA650_25185	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AA650_25190	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA650_25215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA650_25315	ENOG4105CTK	cobaltochelatase, cobn subunit
AA650_25395	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AA650_25410	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AA650_25415	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AA650_25430	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AA650_25435	ENOG41086B8	CoB-CoM heterodisulfide reductase
AA650_25440	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AA650_25555	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AA650_25580	ENOG4105CEY	Amp-dependent synthetase and ligase
AA650_25645	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AA650_25650	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AA650_25705	ENOG4105FA0	parb-like partition protein
AA650_25710	ENOG4107QJE	Chromosome Partitioning Protein
AA650_25715	ENOG4105CPN	adenine deaminase
AA650_25815	ENOG4105GJD	protein, conserved in bacteria
AA650_25855	ENOG4105EKQ	RNA-directed DNA polymerase