locus-tag	class	description
EH233_00010	COG0242	peptide deformylase activity
EH233_00025	COG2217	Heavy metal translocating P-type atpase
EH233_00040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH233_00045	COG2095	MarC family integral membrane protein
EH233_00055	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EH233_00060	COG0438	transferase activity, transferring glycosyl groups
EH233_00070	COG1177	transmembrane transport
EH233_00075	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_00075	COG0515	serine threonine protein kinase
EH233_00115	COG0352	thiamine-phosphate diphosphorylase activity
EH233_00135	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH233_00140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EH233_00180	COG3224	Antibiotic biosynthesis monooxygenase
EH233_00185	COG1335	isochorismatase
EH233_00190	COG2319	Wd-40 repeat
EH233_00190	COG3903	Transcriptional regulator
EH233_00205	COG0330	HflC and HflK could
EH233_00215	COG0671	phosphoesterase, PA-phosphatase related
EH233_00220	COG0730	response to heat
EH233_00230	COG0583	DNA-binding transcription factor activity
EH233_00255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH233_00260	COG1959	2 iron, 2 sulfur cluster binding
EH233_00265	COG1045	serine acetyltransferase
EH233_00270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH233_00290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_00300	COG0625	glutathione transferase activity
EH233_00305	COG0667	Aldo Keto reductase
EH233_00310	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
EH233_00340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_00345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_00355	COG0644	oxidoreductase
EH233_00370	COG0625	glutathione transferase activity
EH233_00380	COG0408	coproporphyrinogen oxidase activity
EH233_00400	COG1132	(ABC) transporter
EH233_00405	COG1252	NADH dehydrogenase
EH233_00410	COG4172	Belongs to the ABC transporter superfamily
EH233_00430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH233_00440	COG1122	ATPase activity
EH233_00470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH233_00470	COG0678	peroxiredoxin activity
EH233_00485	COG0697	spore germination
EH233_00540	COG4771	TonB-dependent receptor
EH233_00590	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EH233_00615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EH233_00620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EH233_00665	COG0590	tRNA wobble adenosine to inosine editing
EH233_00685	COG1595	DNA-templated transcription, initiation
EH233_00695	COG1376	ErfK ybiS ycfS ynhG family protein
EH233_00705	COG0739	heme binding
EH233_00705	COG1196	nuclear chromosome segregation
EH233_00705	COG0741	lytic transglycosylase activity
EH233_00715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EH233_00720	COG1619	proteins homologs of microcin C7 resistance protein MccF
EH233_00735	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_00735	COG0515	serine threonine protein kinase
EH233_00760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EH233_00760	COG0140	phosphoribosyl-ATP diphosphatase activity
EH233_00775	COG0745	RESPONSE REGULATOR receiver
EH233_00810	COG2501	S4 domain
EH233_00815	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_00845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_00860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH233_00865	COG0784	Response regulator, receiver
EH233_00895	COG0512	Glutamine amidotransferase of anthranilate synthase
EH233_00895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EH233_00925	COG0582	viral genome integration into host DNA
EH233_00945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EH233_00960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EH233_00970	COG0432	Pfam Uncharacterised protein family UPF0047
EH233_00995	COG2337	Toxic component of a toxin-antitoxin (TA) module
EH233_01010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH233_01025	COG0515	serine threonine protein kinase
EH233_01030	COG0515	serine threonine protein kinase
EH233_01055	COG3265	gluconokinase activity
EH233_01065	COG1104	cysteine desulfurase activity
EH233_01070	COG0515	serine threonine protein kinase
EH233_01070	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_01110	COG1472	Belongs to the glycosyl hydrolase 3 family
EH233_01125	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EH233_01130	COG0438	transferase activity, transferring glycosyl groups
EH233_01135	COG3307	-O-antigen
EH233_01140	COG0438	transferase activity, transferring glycosyl groups
EH233_01145	COG1442	glycosyl transferase family 8
EH233_01145	COG1216	Glycosyl transferase, family 2
EH233_01185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_01205	COG0170	dolichyl monophosphate biosynthetic process
EH233_01215	COG1836	PFAM Integral membrane protein DUF92
EH233_01230	COG1404	Belongs to the peptidase S8 family
EH233_01245	COG4636	protein conserved in cyanobacteria
EH233_01250	COG1131	(ABC) transporter
EH233_01270	COG0788	formyltetrahydrofolate deformylase activity
EH233_01275	COG2217	Heavy metal translocating P-type atpase
EH233_01295	COG1404	Belongs to the peptidase S8 family
EH233_01300	COG0464	growth
EH233_01305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EH233_01325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH233_01325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH233_01355	COG1857	crispr-associated protein
EH233_01395	COG0789	Transcriptional regulator
EH233_01400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH233_01405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH233_01410	COG3119	arylsulfatase activity
EH233_01425	COG5554	nitrogen fixation
EH233_01430	COG0535	radical SAM domain protein
EH233_01430	COG1433	Dinitrogenase iron-molybdenum cofactor
EH233_01470	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_01540	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EH233_01555	COG4251	negative regulation of phosphorylation
EH233_01555	COG5001	Diguanylate cyclase
EH233_01555	COG3706	GGDEF domain
EH233_01555	COG2203	Gaf domain
EH233_01560	COG0003	Pfam Anion-transporting ATPase
EH233_01600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EH233_01620	COG0121	glutamine amidotransferase
EH233_01625	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH233_01630	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EH233_01645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH233_01675	COG1619	proteins homologs of microcin C7 resistance protein MccF
EH233_01685	COG0415	Belongs to the DNA photolyase family
EH233_01690	COG2204	response regulator
EH233_01720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH233_01730	COG1845	cytochrome c oxidase, subunit III
EH233_01760	COG4191	Histidine kinase
EH233_01775	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EH233_01785	COG0612	Peptidase, M16
EH233_01790	COG0612	Peptidase, M16
EH233_01800	COG1950	PFAM Membrane protein of
EH233_01825	COG0702	epimerase
EH233_01835	COG0596	Alpha beta hydrolase
EH233_01845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EH233_01850	COG1937	Protein conserved in bacteria
EH233_01855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_01865	COG4191	Histidine kinase
EH233_01870	COG5002	protein histidine kinase activity
EH233_01885	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_01900	COG0697	spore germination
EH233_01925	COG4106	trans-aconitate 2-methyltransferase activity
EH233_01930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EH233_01945	COG3237	CsbD-like
EH233_01955	COG0556	nucleotide-excision repair
EH233_01995	COG1196	nuclear chromosome segregation
EH233_02000	COG1252	NADH dehydrogenase
EH233_02005	COG1252	NADH dehydrogenase
EH233_02015	COG0625	glutathione transferase activity
EH233_02020	COG3631	Ketosteroid isomerase-related protein
EH233_02025	COG0589	response to stress
EH233_02030	COG2205	protein histidine kinase activity
EH233_02030	COG0784	Response regulator, receiver
EH233_02045	COG0438	transferase activity, transferring glycosyl groups
EH233_02055	COG5002	protein histidine kinase activity
EH233_02055	COG0784	Response regulator, receiver
EH233_02060	COG3706	GGDEF domain
EH233_02060	COG0745	RESPONSE REGULATOR receiver
EH233_02090	COG2267	carboxylic ester hydrolase activity
EH233_02095	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_02100	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_02110	COG4208	sulfate ABC transporter
EH233_02115	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EH233_02120	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH233_02125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH233_02150	COG0121	glutamine amidotransferase
EH233_02155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EH233_02165	COG5002	protein histidine kinase activity
EH233_02185	COG0584	glycerophosphoryl diester phosphodiesterase
EH233_02225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH233_02250	COG2207	Transcriptional regulator
EH233_02255	COG4221	oxidoreductase activity
EH233_02255	COG0300	oxidoreductase activity
EH233_02255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_02255	COG3321	synthase
EH233_02265	COG3321	synthase
EH233_02265	COG0604	alcohol dehydrogenase
EH233_02275	COG0604	alcohol dehydrogenase
EH233_02275	COG3321	synthase
EH233_02295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EH233_02295	COG2070	2-Nitropropane dioxygenase
EH233_02310	COG0314	molybdopterin synthase activity
EH233_02335	COG0778	Nitroreductase
EH233_02340	COG1902	pentaerythritol trinitrate reductase activity
EH233_02345	COG3118	belongs to the thioredoxin family
EH233_02350	COG0640	Transcriptional regulator
EH233_02360	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_02360	COG0515	serine threonine protein kinase
EH233_02400	COG2217	Heavy metal translocating P-type atpase
EH233_02410	COG0288	reversible hydration of carbon dioxide
EH233_02415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_02430	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_02440	COG0484	heat shock protein binding
EH233_02445	COG0483	inositol monophosphate 1-phosphatase activity
EH233_02460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH233_02470	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_02490	COG1040	competence protein
EH233_02500	COG0724	RNA recognition motif
EH233_02505	COG3338	carbonate dehydratase activity
EH233_02535	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EH233_02545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH233_02555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EH233_02565	COG0613	PHP domain protein
EH233_02580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH233_02585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EH233_02585	COG0284	orotidine-5'-phosphate decarboxylase activity
EH233_02590	COG0628	permease
EH233_02615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH233_02620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EH233_02625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EH233_02635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EH233_02635	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EH233_02655	COG0300	oxidoreductase activity
EH233_02680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_02690	COG1053	succinate dehydrogenase
EH233_02715	COG0681	Belongs to the peptidase S26 family
EH233_02760	COG3781	membrane
EH233_02770	COG2234	aminopeptidase activity
EH233_02780	COG0484	heat shock protein binding
EH233_02790	COG0484	heat shock protein binding
EH233_02810	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EH233_02815	COG0019	diaminopimelate decarboxylase activity
EH233_02820	COG0456	acetyltransferase
EH233_02825	COG0542	response to heat
EH233_02880	COG0390	transport system, permease component
EH233_02915	COG1573	uracil-dna glycosylase
EH233_02925	COG0668	transmembrane transport
EH233_02960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EH233_02985	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EH233_02995	COG1116	anion transmembrane transporter activity
EH233_03000	COG1116	anion transmembrane transporter activity
EH233_03000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_03005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH233_03010	COG3437	response regulator, receiver
EH233_03010	COG3850	Histidine kinase
EH233_03010	COG4999	Histidine kinase
EH233_03010	COG2205	protein histidine kinase activity
EH233_03020	COG1233	COG1233 Phytoene dehydrogenase and related
EH233_03030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_03035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_03040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_03065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EH233_03125	COG2363	Small membrane protein
EH233_03130	COG4451	ribulose bisphosphate carboxylase, small
EH233_03130	COG0464	growth
EH233_03145	COG4451	ribulose bisphosphate carboxylase, small
EH233_03175	COG0531	amino acid
EH233_03210	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_03235	COG2124	cytochrome p450
EH233_03245	COG4782	Protein conserved in bacteria
EH233_03255	COG4636	protein conserved in cyanobacteria
EH233_03270	COG0582	viral genome integration into host DNA
EH233_03275	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_03285	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_03290	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_03305	COG5420	small protein containing a coiled-coil domain
EH233_03395	COG1045	serine acetyltransferase
EH233_03410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_03415	COG5554	nitrogen fixation
EH233_03420	COG5554	nitrogen fixation
EH233_03445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EH233_03460	COG0066	3-isopropylmalate dehydratase activity
EH233_03470	COG0300	oxidoreductase activity
EH233_03475	COG2264	protein methyltransferase activity
EH233_03505	COG5002	protein histidine kinase activity
EH233_03505	COG0784	Response regulator, receiver
EH233_03505	COG2198	Histidine kinase
EH233_03530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EH233_03565	COG0318	PFAM AMP-dependent synthetase and ligase
EH233_03615	COG2815	serine threonine protein kinase
EH233_03615	COG0515	serine threonine protein kinase
EH233_03620	COG0737	Belongs to the 5'-nucleotidase family
EH233_03715	COG1940	carbohydrate kinase activity
EH233_03725	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EH233_03735	COG0742	ribosomal rna small subunit methyltransferase
EH233_03750	COG2010	Cytochrome c
EH233_03765	COG0515	serine threonine protein kinase
EH233_03765	COG2815	serine threonine protein kinase
EH233_03785	COG0589	response to stress
EH233_03795	COG0339	signal peptide processing
EH233_03825	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EH233_03840	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_03845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH233_03850	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_03855	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_03860	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EH233_03870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EH233_03870	COG4451	ribulose bisphosphate carboxylase, small
EH233_03885	COG0583	DNA-binding transcription factor activity
EH233_03895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH233_03900	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EH233_03930	COG2202	Pas domain
EH233_03930	COG2205	protein histidine kinase activity
EH233_03945	COG2267	carboxylic ester hydrolase activity
EH233_03975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH233_04005	COG0123	including yeast histone deacetylase and acetoin utilization protein
EH233_04020	COG3659	wide pore channel activity
EH233_04025	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH233_04030	COG1121	(ABC) transporter
EH233_04035	COG0640	Transcriptional regulator
EH233_04040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH233_04060	COG1902	pentaerythritol trinitrate reductase activity
EH233_04075	COG0745	RESPONSE REGULATOR receiver
EH233_04090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH233_04090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH233_04095	COG2130	NADP-dependent
EH233_04100	COG2831	hemolysin activation secretion protein
EH233_04110	COG1773	rubredoxin
EH233_04115	COG0783	Belongs to the Dps family
EH233_04120	COG1741	Belongs to the pirin family
EH233_04160	COG2267	carboxylic ester hydrolase activity
EH233_04170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH233_04185	COG0505	Belongs to the CarA family
EH233_04270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH233_04310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH233_04325	COG0571	ribonuclease III activity
EH233_04340	COG0598	Magnesium transport protein CorA
EH233_04345	COG0751	glycine-tRNA ligase activity
EH233_04355	COG5002	protein histidine kinase activity
EH233_04360	COG0745	RESPONSE REGULATOR receiver
EH233_04380	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EH233_04395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH233_04400	COG0460	homoserine dehydrogenase
EH233_04410	COG0572	uridine kinase
EH233_04450	COG1051	belongs to the nudix hydrolase family
EH233_04460	COG0589	response to stress
EH233_04525	COG0783	Belongs to the Dps family
EH233_04535	COG2385	sporulation resulting in formation of a cellular spore
EH233_04545	COG0673	inositol 2-dehydrogenase activity
EH233_04550	COG0024	Methionine aminopeptidase
EH233_04565	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_04570	COG4279	zinc finger
EH233_04575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH233_04580	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_04600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_04605	COG0602	queuosine metabolic process
EH233_04620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_04625	COG4597	amino acid ABC transporter
EH233_04630	COG0765	amino acid transport
EH233_04635	COG1126	abc transporter atp-binding protein
EH233_04640	COG0297	glycogen (starch) synthase activity
EH233_04645	COG0799	negative regulation of ribosome biogenesis
EH233_04690	COG0438	transferase activity, transferring glycosyl groups
EH233_04715	COG0488	(ABC) transporter
EH233_04750	COG0101	tRNA pseudouridine synthase activity
EH233_04785	COG0563	adenylate kinase activity
EH233_04790	COG0201	protein transport
EH233_04905	COG0596	Alpha beta hydrolase
EH233_04910	COG3021	interspecies interaction between organisms
EH233_04920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH233_04925	COG0667	Aldo Keto reductase
EH233_04945	COG3228	Belongs to the MtfA family
EH233_04950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EH233_04965	COG0464	growth
EH233_04970	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EH233_04985	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EH233_04990	COG2119	membrane
EH233_05005	COG4636	protein conserved in cyanobacteria
EH233_05035	COG0745	RESPONSE REGULATOR receiver
EH233_05060	COG1131	(ABC) transporter
EH233_05085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH233_05085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH233_05105	COG1077	Cell shape determining protein MreB Mrl
EH233_05110	COG0629	single-stranded DNA binding
EH233_05120	COG0475	glutathione-regulated potassium exporter activity
EH233_05125	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH233_05125	COG2247	cell wall binding repeat
EH233_05145	COG0142	geranyltranstransferase activity
EH233_05165	COG1305	Transglutaminase-like
EH233_05180	COG2052	Domain of unknown function (DUF370)
EH233_05225	COG0454	-acetyltransferase
EH233_05240	COG2890	protein-(glutamine-N5) methyltransferase activity
EH233_05255	COG0454	-acetyltransferase
EH233_05265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH233_05270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH233_05275	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH233_05275	COG0022	dehydrogenase e1 component
EH233_05295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EH233_05305	COG0644	oxidoreductase
EH233_05310	COG0745	RESPONSE REGULATOR receiver
EH233_05315	COG0429	hydrolase of the alpha beta-hydrolase fold
EH233_05345	COG0539	negative regulation of cytoplasmic translation
EH233_05365	COG0747	negative chemotaxis
EH233_05375	COG0328	RNA-DNA hybrid ribonuclease activity
EH233_05420	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EH233_05425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EH233_05430	COG0772	Belongs to the SEDS family
EH233_05460	COG0438	transferase activity, transferring glycosyl groups
EH233_05470	COG2010	Cytochrome c
EH233_05485	COG1950	PFAM Membrane protein of
EH233_05495	COG2183	response to ionizing radiation
EH233_05505	COG1192	Involved in chromosome partitioning
EH233_05545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH233_05570	COG2217	Heavy metal translocating P-type atpase
EH233_05590	COG0515	serine threonine protein kinase
EH233_05590	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_05610	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_05610	COG2319	Wd-40 repeat
EH233_05620	COG0411	ABC transporter
EH233_05635	COG0559	Belongs to the binding-protein-dependent transport system permease family
EH233_05650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_05655	COG1505	serine-type exopeptidase activity
EH233_05660	COG1175	transmembrane transport
EH233_05680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH233_05705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH233_05740	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
EH233_05760	COG0574	Belongs to the PEP-utilizing enzyme family
EH233_05760	COG3848	Pyruvate phosphate dikinase
EH233_05780	COG1104	cysteine desulfurase activity
EH233_05790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH233_05795	COG2815	serine threonine protein kinase
EH233_05795	COG0515	serine threonine protein kinase
EH233_05805	COG0793	Belongs to the peptidase S41A family
EH233_05820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EH233_05830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH233_05835	COG0719	Fe-S assembly protein
EH233_05840	COG0396	ATPase activity
EH233_05845	COG0719	Fe-S assembly protein
EH233_05875	COG1131	(ABC) transporter
EH233_05880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH233_05880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EH233_05890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EH233_05905	COG3852	Histidine kinase
EH233_05915	COG1316	TRANSCRIPTIONal
EH233_05925	COG0628	permease
EH233_05940	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EH233_05950	COG0330	HflC and HflK could
EH233_06025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EH233_06040	COG0805	protein transport
EH233_06065	COG1543	Belongs to the glycosyl hydrolase 57 family
EH233_06085	COG0443	Heat shock 70 kDa protein
EH233_06095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EH233_06120	COG4636	protein conserved in cyanobacteria
EH233_06130	COG3932	Exopolysaccharide synthesis, ExoD
EH233_06135	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EH233_06135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_06180	COG0438	transferase activity, transferring glycosyl groups
EH233_06185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH233_06230	COG2204	response regulator
EH233_06255	COG2814	Major facilitator Superfamily
EH233_06260	COG0463	Glycosyl transferase, family 2
EH233_06280	COG1305	Transglutaminase-like
EH233_06285	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_06300	COG1285	pathogenesis
EH233_06305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH233_06305	COG0574	Belongs to the PEP-utilizing enzyme family
EH233_06325	COG0515	serine threonine protein kinase
EH233_06335	COG0631	protein serine/threonine phosphatase activity
EH233_06340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH233_06345	COG3937	granule-associated protein
EH233_06355	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH233_06400	COG0745	RESPONSE REGULATOR receiver
EH233_06405	COG5002	protein histidine kinase activity
EH233_06410	COG0704	Plays a role in the regulation of phosphate uptake
EH233_06415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_06420	COG3659	wide pore channel activity
EH233_06435	COG0784	Response regulator, receiver
EH233_06435	COG2205	protein histidine kinase activity
EH233_06445	COG0438	transferase activity, transferring glycosyl groups
EH233_06450	COG4106	trans-aconitate 2-methyltransferase activity
EH233_06470	COG1091	dTDP-4-dehydrorhamnose reductase activity
EH233_06485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_06490	COG0463	Glycosyl transferase, family 2
EH233_06535	COG0003	Pfam Anion-transporting ATPase
EH233_06540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH233_06545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_06580	COG0483	inositol monophosphate 1-phosphatase activity
EH233_06595	COG0175	sulfate reduction
EH233_06610	COG1247	-acetyltransferase
EH233_06635	COG1598	PFAM Uncharacterised protein family UPF0150
EH233_06710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_06720	COG5002	protein histidine kinase activity
EH233_06725	COG0745	RESPONSE REGULATOR receiver
EH233_06730	COG2203	Gaf domain
EH233_06730	COG3706	GGDEF domain
EH233_06730	COG4251	negative regulation of phosphorylation
EH233_06730	COG5001	Diguanylate cyclase
EH233_06740	COG0643	Histidine kinase
EH233_06740	COG2198	Histidine kinase
EH233_06745	COG0840	transmembrane signaling receptor activity
EH233_06760	COG0784	Response regulator, receiver
EH233_06770	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH233_06770	COG3409	Peptidoglycan-binding domain 1 protein
EH233_06775	COG4191	Histidine kinase
EH233_06775	COG0784	Response regulator, receiver
EH233_06815	COG0581	inorganic phosphate transmembrane transporter activity
EH233_06820	COG0573	inorganic phosphate transmembrane transporter activity
EH233_06825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH233_06830	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH233_06855	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_06855	COG2319	Wd-40 repeat
EH233_06865	COG0723	plastoquinol--plastocyanin reductase activity
EH233_06875	COG1480	7TM receptor with intracellular HD hydrolase
EH233_06885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EH233_06890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH233_06890	COG1754	DNA topoisomerase type I activity
EH233_06905	COG0724	RNA recognition motif
EH233_06910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH233_06930	COG2205	protein histidine kinase activity
EH233_06935	COG0129	dihydroxy-acid dehydratase activity
EH233_06940	COG0463	Glycosyl transferase, family 2
EH233_06945	COG0352	thiamine-phosphate diphosphorylase activity
EH233_06945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EH233_06945	COG0351	phosphomethylpyrimidine kinase
EH233_06965	COG0640	Transcriptional regulator
EH233_06970	COG0436	Aminotransferase
EH233_06975	COG0371	Dehydrogenase
EH233_06990	COG2267	carboxylic ester hydrolase activity
EH233_07030	COG4106	trans-aconitate 2-methyltransferase activity
EH233_07035	COG0601	transmembrane transport
EH233_07040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_07045	COG0592	DNA-directed DNA polymerase activity
EH233_07055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_07060	COG1575	Belongs to the MenA family. Type 1 subfamily
EH233_07065	COG1169	isochorismate synthase
EH233_07080	COG2319	Wd-40 repeat
EH233_07080	COG3903	Transcriptional regulator
EH233_07105	COG2912	Transglutaminase-like superfamily
EH233_07125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH233_07125	COG0237	dephospho-CoA kinase activity
EH233_07135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH233_07205	COG2226	methyltransferase
EH233_07245	COG2091	lysine biosynthetic process via aminoadipic acid
EH233_07250	COG0300	oxidoreductase activity
EH233_07260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_07260	COG3320	Male sterility
EH233_07265	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EH233_07265	COG2070	2-Nitropropane dioxygenase
EH233_07270	COG4221	oxidoreductase activity
EH233_07270	COG3321	synthase
EH233_07270	COG0300	oxidoreductase activity
EH233_07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_07280	COG4221	oxidoreductase activity
EH233_07280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH233_07280	COG3321	synthase
EH233_07280	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_07285	COG3321	synthase
EH233_07285	COG0604	alcohol dehydrogenase
EH233_07300	COG1475	DNA binding
EH233_07350	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH233_07440	COG0438	transferase activity, transferring glycosyl groups
EH233_07455	COG0426	domain, Protein
EH233_07455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_07465	COG0426	domain, Protein
EH233_07465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_07485	COG1691	(AIR) carboxylase
EH233_07490	COG0747	negative chemotaxis
EH233_07515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH233_07525	COG0515	serine threonine protein kinase
EH233_07525	COG3266	domain, Protein
EH233_07535	COG0575	Belongs to the CDS family
EH233_07545	COG1187	pseudouridine synthase activity
EH233_07550	COG1426	Protein conserved in bacteria
EH233_07555	COG1640	4-alpha-glucanotransferase
EH233_07565	COG0251	oxidation-reduction process
EH233_07575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH233_07620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH233_07625	COG0189	ligase activity
EH233_07630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EH233_07650	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_07650	COG2319	Wd-40 repeat
EH233_07665	COG1191	sigma factor activity
EH233_07795	COG0195	Participates in both transcription termination and antitermination
EH233_07830	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EH233_07895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH233_07925	COG1216	Glycosyl transferase, family 2
EH233_07950	COG0586	Pfam SNARE associated Golgi protein
EH233_07970	COG0179	Fumarylacetoacetate (FAA) hydrolase
EH233_07990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH233_08000	COG4636	protein conserved in cyanobacteria
EH233_08025	COG3266	domain, Protein
EH233_08025	COG0515	serine threonine protein kinase
EH233_08045	COG4115	mRNA cleavage
EH233_08055	COG0038	chloride channel
EH233_08075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_08080	COG0395	ABC-type sugar transport system, permease component
EH233_08085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EH233_08090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_08095	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EH233_08100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_08105	COG0438	transferase activity, transferring glycosyl groups
EH233_08120	COG2124	cytochrome p450
EH233_08125	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_08125	COG2319	Wd-40 repeat
EH233_08150	COG0515	serine threonine protein kinase
EH233_08150	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_08165	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EH233_08170	COG0514	ATP-dependent DNA helicase (RecQ)
EH233_08175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH233_08190	COG1234	tRNA 3'-trailer cleavage
EH233_08195	COG0196	riboflavin kinase activity
EH233_08200	COG0714	Associated with various cellular activities
EH233_08225	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EH233_08235	COG0436	Aminotransferase
EH233_08250	COG4680	protein conserved in bacteria
EH233_08255	COG0457	Tetratricopeptide repeat
EH233_08255	COG0463	Glycosyl transferase, family 2
EH233_08285	COG1696	Membrane protein involved in D-alanine export
EH233_08320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH233_08325	COG4178	(ABC) transporter
EH233_08355	COG4178	(ABC) transporter
EH233_08365	COG1672	PFAM Archaeal ATPase
EH233_08365	COG2319	Wd-40 repeat
EH233_08380	COG3437	response regulator, receiver
EH233_08385	COG2202	Pas domain
EH233_08385	COG2205	protein histidine kinase activity
EH233_08400	COG0668	transmembrane transport
EH233_08405	COG0475	glutathione-regulated potassium exporter activity
EH233_08450	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
EH233_08460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EH233_08475	COG1696	Membrane protein involved in D-alanine export
EH233_08480	COG3321	synthase
EH233_08480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_08480	COG0300	oxidoreductase activity
EH233_08480	COG4221	oxidoreductase activity
EH233_08485	COG1960	acyl-CoA dehydrogenase activity
EH233_08490	COG0318	PFAM AMP-dependent synthetase and ligase
EH233_08500	COG0354	folic acid binding
EH233_08510	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EH233_08520	COG3959	Transketolase, thiamine diphosphate binding domain
EH233_08540	COG0435	Glutathione S-transferase
EH233_08590	COG1045	serine acetyltransferase
EH233_08595	COG0259	pyridoxamine-phosphate oxidase activity
EH233_08640	COG0724	RNA recognition motif
EH233_08650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH233_08655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH233_08660	COG3409	Peptidoglycan-binding domain 1 protein
EH233_08660	COG3429	Glucose-6-phosphate dehydrogenase subunit
EH233_08680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EH233_08690	COG0616	signal peptide processing
EH233_08700	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EH233_08715	COG0469	pyruvate kinase activity
EH233_08745	COG3266	domain, Protein
EH233_08745	COG0515	serine threonine protein kinase
EH233_08755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EH233_08800	COG3609	addiction module antidote protein, CC2985 family
EH233_08810	COG0419	ATPase involved in DNA repair
EH233_08815	COG2205	protein histidine kinase activity
EH233_08815	COG0784	Response regulator, receiver
EH233_08830	COG5002	protein histidine kinase activity
EH233_08885	COG0750	zinc metalloprotease
EH233_08890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EH233_08920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH233_08965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH233_08970	COG3118	belongs to the thioredoxin family
EH233_08985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_08990	COG0018	arginyl-trna synthetase
EH233_08995	COG0561	phosphatase activity
EH233_09000	COG1122	ATPase activity
EH233_09010	COG0310	cobalt ion transport
EH233_09015	COG1122	ATPase activity
EH233_09025	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EH233_09030	COG0310	cobalt ion transport
EH233_09035	COG2132	Multicopper oxidase
EH233_09050	COG0672	)-iron permease
EH233_09055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH233_09065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH233_09070	COG0776	regulation of translation
EH233_09190	COG0716	FMN binding
EH233_09200	COG0745	RESPONSE REGULATOR receiver
EH233_09225	COG2205	protein histidine kinase activity
EH233_09245	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EH233_09265	COG1902	pentaerythritol trinitrate reductase activity
EH233_09275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EH233_09295	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH233_09295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH233_09300	COG0443	Heat shock 70 kDa protein
EH233_09315	COG0656	L-ascorbic acid biosynthetic process
EH233_09330	COG0484	heat shock protein binding
EH233_09340	COG0542	response to heat
EH233_09360	COG2080	2 iron, 2 sulfur cluster binding
EH233_09365	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EH233_09370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EH233_09375	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EH233_09380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EH233_09385	COG1475	DNA binding
EH233_09395	COG1192	Involved in chromosome partitioning
EH233_09415	COG2815	serine threonine protein kinase
EH233_09415	COG0515	serine threonine protein kinase
EH233_09420	COG2197	response regulator
EH233_09425	COG2207	Transcriptional regulator
EH233_09440	COG4221	oxidoreductase activity
EH233_09445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH233_09445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH233_09460	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_09480	COG2267	carboxylic ester hydrolase activity
EH233_09510	COG1429	ligase activity, forming nitrogen-metal bonds
EH233_09515	COG1132	(ABC) transporter
EH233_09520	COG1132	(ABC) transporter
EH233_09530	COG0745	RESPONSE REGULATOR receiver
EH233_09535	COG5000	phosphorelay sensor kinase activity
EH233_09535	COG5002	protein histidine kinase activity
EH233_09540	COG0113	porphobilinogen synthase activity
EH233_09545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH233_09550	COG0523	cobalamin synthesis protein
EH233_09555	COG0302	gtp cyclohydrolase
EH233_09565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_09570	COG0513	Belongs to the DEAD box helicase family
EH233_09580	COG5002	protein histidine kinase activity
EH233_09585	COG1132	(ABC) transporter
EH233_09595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EH233_09610	COG2234	aminopeptidase activity
EH233_09645	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EH233_09690	COG1846	Transcriptional regulator
EH233_09700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH233_09720	COG2124	cytochrome p450
EH233_09725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_09735	COG0724	RNA recognition motif
EH233_09740	COG1218	3'(2'),5'-bisphosphate nucleotidase
EH233_09750	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EH233_09795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EH233_09800	COG0515	serine threonine protein kinase
EH233_09800	COG3266	domain, Protein
EH233_09815	COG0857	belongs to the CobB CobQ family
EH233_09835	COG0625	glutathione transferase activity
EH233_09860	COG1070	Carbohydrate kinase
EH233_09865	COG2971	BadF BadG BcrA BcrD
EH233_09880	COG3237	CsbD-like
EH233_09915	COG0800	Aldolase
EH233_09925	COG2066	Belongs to the glutaminase family
EH233_09935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_09940	COG0431	NADPH-dependent FMN reductase
EH233_09950	COG0745	RESPONSE REGULATOR receiver
EH233_09955	COG5002	protein histidine kinase activity
EH233_09965	COG3659	wide pore channel activity
EH233_09975	COG1132	(ABC) transporter
EH233_09980	COG0438	transferase activity, transferring glycosyl groups
EH233_10000	COG2239	Acts as a magnesium transporter
EH233_10010	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_10030	COG0725	ABC transporter, periplasmic molybdate-binding protein
EH233_10050	COG5002	protein histidine kinase activity
EH233_10055	COG0745	RESPONSE REGULATOR receiver
EH233_10095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_10140	COG1234	tRNA 3'-trailer cleavage
EH233_10165	COG2274	protein secretion by the type I secretion system
EH233_10200	COG2226	methyltransferase
EH233_10215	COG0463	Glycosyl transferase, family 2
EH233_10255	COG0303	'Molybdopterin
EH233_10265	COG2119	membrane
EH233_10315	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_10325	COG1131	(ABC) transporter
EH233_10335	COG0517	IMP dehydrogenase activity
EH233_10335	COG1125	glycine betaine transport
EH233_10360	COG0004	ammonium transporteR
EH233_10365	COG0004	ammonium transporteR
EH233_10370	COG0004	ammonium transporteR
EH233_10375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EH233_10380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EH233_10415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH233_10420	COG2205	protein histidine kinase activity
EH233_10430	COG1012	belongs to the aldehyde dehydrogenase family
EH233_10440	COG2226	methyltransferase
EH233_10445	COG0237	dephospho-CoA kinase activity
EH233_10455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH233_10460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH233_10465	COG1413	lyase activity
EH233_10470	COG1413	lyase activity
EH233_10475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH233_10480	COG0237	dephospho-CoA kinase activity
EH233_10495	COG1413	lyase activity
EH233_10500	COG1413	lyase activity
EH233_10505	COG0237	dephospho-CoA kinase activity
EH233_10520	COG0564	pseudouridine synthase activity
EH233_10525	COG0784	Response regulator, receiver
EH233_10530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH233_10560	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EH233_10565	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_10575	COG3956	TIGRFAM MazG family protein
EH233_10610	COG0489	protein tyrosine kinase activity
EH233_10610	COG3206	protein involved in exopolysaccharide biosynthesis
EH233_10630	COG0463	Glycosyl transferase, family 2
EH233_10630	COG1216	Glycosyl transferase, family 2
EH233_10640	COG4581	dead DEAH box helicase
EH233_10645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH233_10655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EH233_10665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EH233_10720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_10740	COG2442	InterPro IPR007367
EH233_10750	COG4804	nuclease activity
EH233_10785	COG1518	maintenance of DNA repeat elements
EH233_10790	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EH233_10810	COG2831	hemolysin activation secretion protein
EH233_10915	COG0589	response to stress
EH233_10925	COG0268	Binds directly to 16S ribosomal RNA
EH233_10930	COG0084	hydrolase, TatD family'
EH233_10955	COG3239	Fatty acid desaturase
EH233_10960	COG3239	Fatty acid desaturase
EH233_10970	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EH233_10975	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
EH233_10985	COG0363	glucosamine-6-phosphate deaminase activity
EH233_10990	COG1716	ATPase activity
EH233_11000	COG2385	sporulation resulting in formation of a cellular spore
EH233_11030	COG0577	efflux transmembrane transporter activity
EH233_11030	COG1136	(ABC) transporter
EH233_11035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EH233_11050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH233_11070	COG0017	Asparaginyl-tRNA synthetase
EH233_11085	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EH233_11110	COG1192	Involved in chromosome partitioning
EH233_11145	COG0745	RESPONSE REGULATOR receiver
EH233_11145	COG3706	GGDEF domain
EH233_11150	COG1012	belongs to the aldehyde dehydrogenase family
EH233_11155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH233_11180	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH233_11190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EH233_11195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH233_11200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH233_11210	COG0740	serine-type endopeptidase activity
EH233_11255	COG0668	transmembrane transport
EH233_11285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EH233_11335	COG1690	Belongs to the RtcB family
EH233_11340	COG2226	methyltransferase
EH233_11360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EH233_11365	COG1166	arginine decarboxylase activity
EH233_11375	COG0861	Integral membrane protein TerC family
EH233_11390	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EH233_11395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EH233_11400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EH233_11425	COG0706	membrane insertase activity
EH233_11455	COG0793	Belongs to the peptidase S41A family
EH233_11480	COG0438	transferase activity, transferring glycosyl groups
EH233_11500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_11520	COG0745	RESPONSE REGULATOR receiver
EH233_11530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EH233_11560	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_11565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH233_11590	COG0322	excinuclease ABC activity
EH233_11605	COG0512	Glutamine amidotransferase of anthranilate synthase
EH233_11605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EH233_11625	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH233_11635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH233_11650	COG0850	regulation of cytokinetic process
EH233_11655	COG2894	cell division
EH233_11720	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH233_11720	COG3409	Peptidoglycan-binding domain 1 protein
EH233_11730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_11765	COG2770	Histidine kinase
EH233_11765	COG3437	response regulator, receiver
EH233_11805	COG0745	RESPONSE REGULATOR receiver
EH233_11865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EH233_11890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH233_11895	COG1530	ribonuclease E activity
EH233_11915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EH233_11945	COG0316	Belongs to the HesB IscA family
EH233_11950	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EH233_11950	COG0662	Cupin 2, conserved barrel domain protein
EH233_11960	COG0069	glutamate synthase activity
EH233_11960	COG0067	glutamate synthase
EH233_11960	COG0070	glutamate synthase
EH233_11965	COG0726	polysaccharide deacetylase
EH233_11975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EH233_12020	COG0538	isocitrate dehydrogenase activity
EH233_12025	COG0515	serine threonine protein kinase
EH233_12030	COG3842	ATPase activity
EH233_12045	COG4636	protein conserved in cyanobacteria
EH233_12055	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_12105	COG2319	Wd-40 repeat
EH233_12105	COG1672	PFAM Archaeal ATPase
EH233_12140	COG2226	methyltransferase
EH233_12145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EH233_12150	COG0569	domain protein
EH233_12185	COG0726	polysaccharide deacetylase
EH233_12195	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EH233_12195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_12200	COG1562	ergosterol biosynthetic process
EH233_12255	COG0517	IMP dehydrogenase activity
EH233_12255	COG1994	Peptidase M50
EH233_12265	COG2202	Pas domain
EH233_12265	COG2205	protein histidine kinase activity
EH233_12275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EH233_12280	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_12285	COG2205	protein histidine kinase activity
EH233_12285	COG0784	Response regulator, receiver
EH233_12300	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EH233_12310	COG0181	hydroxymethylbilane synthase activity
EH233_12320	COG1597	lipid kinase activity
EH233_12320	COG1803	Methylglyoxal synthase
EH233_12330	COG0157	Belongs to the NadC ModD family
EH233_12345	COG2326	polyphosphate kinase activity
EH233_12350	COG0724	RNA recognition motif
EH233_12375	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EH233_12380	COG1959	2 iron, 2 sulfur cluster binding
EH233_12415	COG0346	lactoylglutathione lyase activity
EH233_12420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EH233_12425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EH233_12435	COG1295	ribonuclease BN
EH233_12455	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EH233_12510	COG0667	Aldo Keto reductase
EH233_12565	COG0405	Gamma-glutamyltransferase
EH233_12575	COG0745	RESPONSE REGULATOR receiver
EH233_12575	COG3706	GGDEF domain
EH233_12580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EH233_12590	COG4651	solute:proton antiporter activity
EH233_12590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EH233_12595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_12600	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EH233_12600	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EH233_12615	COG0571	ribonuclease III activity
EH233_12625	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_12625	COG2319	Wd-40 repeat
EH233_12650	COG0793	Belongs to the peptidase S41A family
EH233_12655	COG1215	transferase activity, transferring glycosyl groups
EH233_12735	COG0671	phosphoesterase, PA-phosphatase related
EH233_12740	COG0308	aminopeptidase N
EH233_12750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH233_12780	COG0438	transferase activity, transferring glycosyl groups
EH233_12785	COG1132	(ABC) transporter
EH233_12810	COG0305	Participates in initiation and elongation during chromosome replication
EH233_12810	COG1372	Participates in initiation and elongation during chromosome replication
EH233_12810	COG1372	Participates in initiation and elongation during chromosome replication
EH233_12810	COG0305	Participates in initiation and elongation during chromosome replication
EH233_12830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH233_12850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH233_12880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EH233_12965	COG0515	serine threonine protein kinase
EH233_12965	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_12975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EH233_12980	COG2205	protein histidine kinase activity
EH233_12980	COG3850	Histidine kinase
EH233_12980	COG4999	Histidine kinase
EH233_12980	COG3437	response regulator, receiver
EH233_13000	COG0475	glutathione-regulated potassium exporter activity
EH233_13005	COG0347	Belongs to the P(II) protein family
EH233_13020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH233_13045	COG0488	(ABC) transporter
EH233_13060	COG1132	(ABC) transporter
EH233_13095	COG1606	tRNA processing
EH233_13100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_13100	COG2205	protein histidine kinase activity
EH233_13100	COG2198	Histidine kinase
EH233_13100	COG0784	Response regulator, receiver
EH233_13115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EH233_13120	COG0784	Response regulator, receiver
EH233_13125	COG5001	Diguanylate cyclase
EH233_13125	COG3706	GGDEF domain
EH233_13125	COG2203	Gaf domain
EH233_13125	COG4251	negative regulation of phosphorylation
EH233_13130	COG5002	protein histidine kinase activity
EH233_13145	COG0110	maltose O-acetyltransferase activity
EH233_13175	COG0180	Tryptophanyl-tRNA synthetase
EH233_13215	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EH233_13230	COG0525	valine-tRNA ligase activity
EH233_13235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EH233_13240	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_13260	COG2239	Acts as a magnesium transporter
EH233_13280	COG2205	protein histidine kinase activity
EH233_13280	COG2202	Pas domain
EH233_13295	COG0735	belongs to the Fur family
EH233_13300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_13310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EH233_13345	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EH233_13360	COG2815	serine threonine protein kinase
EH233_13360	COG0515	serine threonine protein kinase
EH233_13380	COG5002	protein histidine kinase activity
EH233_13435	COG2207	Transcriptional regulator
EH233_13435	COG0662	Cupin 2, conserved barrel domain protein
EH233_13495	COG0640	Transcriptional regulator
EH233_13515	COG0438	transferase activity, transferring glycosyl groups
EH233_13565	COG1193	negative regulation of DNA recombination
EH233_13575	COG0516	GMP reductase activity
EH233_13580	COG3118	belongs to the thioredoxin family
EH233_13605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH233_13610	COG0489	protein tyrosine kinase activity
EH233_13645	COG0717	Belongs to the dCTP deaminase family
EH233_13655	COG0563	adenylate kinase activity
EH233_13670	COG1127	ABC transporter
EH233_13690	COG0728	peptidoglycan biosynthetic process
EH233_13700	COG1316	TRANSCRIPTIONal
EH233_13710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH233_13715	COG1131	(ABC) transporter
EH233_13725	COG2815	serine threonine protein kinase
EH233_13725	COG0515	serine threonine protein kinase
EH233_13765	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EH233_13770	COG0009	L-threonylcarbamoyladenylate synthase
EH233_13785	COG0514	ATP-dependent DNA helicase (RecQ)
EH233_13805	COG0628	permease
EH233_13810	COG1051	belongs to the nudix hydrolase family
EH233_13820	COG2897	thiosulfate sulfurtransferase activity
EH233_13825	COG4804	nuclease activity
EH233_13830	COG1160	GTP binding
EH233_13840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EH233_13855	COG0581	inorganic phosphate transmembrane transporter activity
EH233_13860	COG0573	inorganic phosphate transmembrane transporter activity
EH233_13865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH233_13870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EH233_13875	COG2197	response regulator
EH233_13910	COG0154	amidase activity
EH233_13965	COG0583	DNA-binding transcription factor activity
EH233_13970	COG3659	wide pore channel activity
EH233_13990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_13995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH233_14000	COG1116	anion transmembrane transporter activity
EH233_14000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_14005	COG1116	anion transmembrane transporter activity
EH233_14010	COG0243	molybdopterin cofactor binding
EH233_14055	COG4106	trans-aconitate 2-methyltransferase activity
EH233_14065	COG0247	lactate metabolic process
EH233_14070	COG0277	FAD linked oxidase domain protein
EH233_14120	COG0006	proline dipeptidase activity
EH233_14130	COG0398	Pfam SNARE associated Golgi protein
EH233_14150	COG0784	Response regulator, receiver
EH233_14150	COG5002	protein histidine kinase activity
EH233_14170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EH233_14175	COG1253	flavin adenine dinucleotide binding
EH233_14185	COG0312	modulator of DNA gyrase
EH233_14190	COG0312	modulator of DNA gyrase
EH233_14205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EH233_14245	COG0398	Pfam SNARE associated Golgi protein
EH233_14250	COG0784	Response regulator, receiver
EH233_14265	COG0395	ABC-type sugar transport system, permease component
EH233_14300	COG0025	NhaP-type Na H and K H
EH233_14305	COG1408	metallophosphoesterase
EH233_14310	COG1408	metallophosphoesterase
EH233_14320	COG0484	heat shock protein binding
EH233_14345	COG0628	permease
EH233_14350	COG0204	Acyl-transferase
EH233_14350	COG0318	PFAM AMP-dependent synthetase and ligase
EH233_14355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EH233_14390	COG1104	cysteine desulfurase activity
EH233_14400	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EH233_14405	COG1061	Type III restriction enzyme res subunit
EH233_14510	COG1372	Participates in initiation and elongation during chromosome replication
EH233_14510	COG0305	Participates in initiation and elongation during chromosome replication
EH233_14665	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_14665	COG0515	serine threonine protein kinase
EH233_14670	COG3903	Transcriptional regulator
EH233_14670	COG2319	Wd-40 repeat
EH233_14690	COG2197	response regulator
EH233_14775	COG0739	heme binding
EH233_14890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_14955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EH233_14965	COG0739	heme binding
EH233_14985	COG3118	belongs to the thioredoxin family
EH233_14990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EH233_15005	COG1131	(ABC) transporter
EH233_15020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH233_15050	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EH233_15065	COG0316	Belongs to the HesB IscA family
EH233_15080	COG1090	epimerase
EH233_15085	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EH233_15135	COG0515	serine threonine protein kinase
EH233_15135	COG3266	domain, Protein
EH233_15140	COG0515	serine threonine protein kinase
EH233_15160	COG3706	GGDEF domain
EH233_15160	COG0745	RESPONSE REGULATOR receiver
EH233_15210	COG0604	alcohol dehydrogenase
EH233_15210	COG3321	synthase
EH233_15220	COG0515	serine threonine protein kinase
EH233_15220	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_15225	COG1136	(ABC) transporter
EH233_15275	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH233_15280	COG1473	amidohydrolase
EH233_15320	COG5002	protein histidine kinase activity
EH233_15335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_15360	COG2897	thiosulfate sulfurtransferase activity
EH233_15365	COG2391	methyltransferase activity
EH233_15370	COG2873	o-acetylhomoserine
EH233_15385	COG0489	protein tyrosine kinase activity
EH233_15440	COG3540	Alkaline phosphatase
EH233_15465	COG2205	protein histidine kinase activity
EH233_15465	COG0784	Response regulator, receiver
EH233_15485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH233_15490	COG3659	wide pore channel activity
EH233_15495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EH233_15515	COG0667	Aldo Keto reductase
EH233_15520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_15530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_15535	COG5001	Diguanylate cyclase
EH233_15535	COG4251	negative regulation of phosphorylation
EH233_15535	COG3706	GGDEF domain
EH233_15535	COG2203	Gaf domain
EH233_15550	COG0412	Dienelactone hydrolase
EH233_15555	COG0778	Nitroreductase
EH233_15560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_15565	COG0626	cystathionine gamma-synthase activity
EH233_15615	COG0811	peptide transport
EH233_15620	COG0848	biopolymer transport protein
EH233_15625	COG0768	penicillin binding
EH233_15635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH233_15640	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH233_15680	COG0714	Associated with various cellular activities
EH233_15700	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EH233_15710	COG0748	coenzyme F420 binding
EH233_15730	COG0438	transferase activity, transferring glycosyl groups
EH233_15735	COG0583	DNA-binding transcription factor activity
EH233_15755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EH233_15780	COG1834	amidinotransferase
EH233_15805	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH233_15820	COG1940	carbohydrate kinase activity
EH233_15830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_15880	COG2909	trisaccharide binding
EH233_15890	COG0517	IMP dehydrogenase activity
EH233_15890	COG0516	GMP reductase activity
EH233_15895	COG0494	nUDIX hydrolase
EH233_15905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_15910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EH233_15915	COG0783	Belongs to the Dps family
EH233_15925	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EH233_15950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_15965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_15970	COG0058	SHG alpha-glucan phosphorylase activity
EH233_15975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_15995	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_16000	COG0401	homolog of Blt101
EH233_16005	COG0023	Translation Initiation Factor
EH233_16025	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EH233_16040	COG0745	RESPONSE REGULATOR receiver
EH233_16045	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EH233_16065	COG0745	RESPONSE REGULATOR receiver
EH233_16090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH233_16140	COG2197	response regulator
EH233_16145	COG5001	Diguanylate cyclase
EH233_16150	COG0784	Response regulator, receiver
EH233_16150	COG2198	Histidine kinase
EH233_16150	COG5002	protein histidine kinase activity
EH233_16155	COG5002	protein histidine kinase activity
EH233_16155	COG0784	Response regulator, receiver
EH233_16160	COG0745	RESPONSE REGULATOR receiver
EH233_16160	COG3706	GGDEF domain
EH233_16170	COG2205	protein histidine kinase activity
EH233_16170	COG5002	protein histidine kinase activity
EH233_16170	COG0784	Response regulator, receiver
EH233_16180	COG0745	RESPONSE REGULATOR receiver
EH233_16210	COG0300	oxidoreductase activity
EH233_16225	COG2226	methyltransferase
EH233_16235	COG0402	S-adenosylhomocysteine deaminase activity
EH233_16290	COG4636	protein conserved in cyanobacteria
EH233_16300	COG1830	Aldolase
EH233_16310	COG3266	domain, Protein
EH233_16310	COG0515	serine threonine protein kinase
EH233_16315	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH233_16320	COG2226	methyltransferase
EH233_16345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EH233_16350	COG0592	DNA-directed DNA polymerase activity
EH233_16425	COG1111	helicase
EH233_16425	COG1205	dead DEAH box helicase
EH233_16435	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EH233_16645	COG0515	serine threonine protein kinase
EH233_16645	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH233_16650	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EH233_16650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH233_16715	COG3706	GGDEF domain
EH233_16725	COG1902	pentaerythritol trinitrate reductase activity
EH233_16730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH233_16735	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EH233_16740	COG2076	Multidrug Resistance protein
EH233_16745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_16790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EH233_16825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_16835	COG0659	secondary active sulfate transmembrane transporter activity
EH233_16900	COG1715	Restriction endonuclease
EH233_17000	COG1061	Type III restriction enzyme res subunit
EH233_17005	COG0583	DNA-binding transcription factor activity
EH233_17010	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EH233_17015	COG3540	Alkaline phosphatase
EH233_17020	COG0577	efflux transmembrane transporter activity
EH233_17020	COG1136	(ABC) transporter
EH233_17035	COG1695	Transcriptional regulator
EH233_17055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH233_17060	COG3150	esterase
EH233_17095	COG0497	DNA recombination
EH233_17100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH233_17115	COG0628	permease
EH233_17130	COG3631	Ketosteroid isomerase-related protein
EH233_17135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH233_17140	COG0546	phosphoglycolate phosphatase activity
EH233_17150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EH233_17165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH233_17170	COG4956	integral membrane protein (PIN domain superfamily)
EH233_17190	COG1473	amidohydrolase
EH233_17220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_17235	COG2207	Transcriptional regulator
EH233_17250	COG2814	Major facilitator Superfamily
EH233_17255	COG3659	wide pore channel activity
EH233_17310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_17360	COG5285	phytanoyl-CoA dioxygenase
EH233_17400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH233_17400	COG0574	Belongs to the PEP-utilizing enzyme family
EH233_17420	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EH233_17430	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EH233_17435	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EH233_17440	COG5002	protein histidine kinase activity
EH233_17450	COG4251	negative regulation of phosphorylation
EH233_17455	COG0784	Response regulator, receiver
EH233_17460	COG2205	protein histidine kinase activity
EH233_17485	COG2217	Heavy metal translocating P-type atpase
EH233_17490	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH233_17505	COG0628	permease
EH233_17520	COG5002	protein histidine kinase activity
EH233_17530	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_17530	COG0515	serine threonine protein kinase
EH233_17575	COG0110	maltose O-acetyltransferase activity
EH233_17660	COG3655	Transcriptional regulator
EH233_17700	COG0557	exoribonuclease II activity
EH233_17730	COG0443	Heat shock 70 kDa protein
EH233_17750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EH233_17765	COG0346	lactoylglutathione lyase activity
EH233_17770	COG2304	oxidoreductase activity
EH233_17775	COG2304	oxidoreductase activity
EH233_17780	COG0740	serine-type endopeptidase activity
EH233_17805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH233_17815	COG4948	Mandelate Racemase Muconate Lactonizing
EH233_17820	COG0494	nUDIX hydrolase
EH233_17830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH233_17830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH233_17835	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EH233_17850	COG0351	phosphomethylpyrimidine kinase
EH233_17890	COG3852	Histidine kinase
EH233_17905	COG0697	spore germination
EH233_17910	COG0248	Ppx GppA phosphatase
EH233_17915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH233_17935	COG1012	belongs to the aldehyde dehydrogenase family
EH233_17940	COG2815	serine threonine protein kinase
EH233_17940	COG0515	serine threonine protein kinase
EH233_17985	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_17995	COG1404	Belongs to the peptidase S8 family
EH233_18015	COG0484	heat shock protein binding
EH233_18025	COG0450	alkyl hydroperoxide reductase
EH233_18045	COG4585	Histidine kinase
EH233_18050	COG2197	response regulator
EH233_18060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_18085	COG0440	acetolactate synthase activity
EH233_18135	COG4172	Belongs to the ABC transporter superfamily
EH233_18140	COG0629	single-stranded DNA binding
EH233_18145	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EH233_18160	COG3842	ATPase activity
EH233_18170	COG3631	Ketosteroid isomerase-related protein
EH233_18185	COG0412	Dienelactone hydrolase
EH233_18195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_18210	COG2124	cytochrome p450
EH233_18210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH233_18230	COG3659	wide pore channel activity
EH233_18265	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_18280	COG1271	oxidase subunit
EH233_18285	COG1294	oxidase, subunit
EH233_18310	COG1910	domain protein
EH233_18315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_18330	COG1122	ATPase activity
EH233_18335	COG1309	transcriptional regulator
EH233_18345	COG0778	Nitroreductase
EH233_18380	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_18405	COG0412	Dienelactone hydrolase
EH233_18410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH233_18450	COG0768	penicillin binding
EH233_18475	COG0012	GTP binding
EH233_18495	COG0363	glucosamine-6-phosphate deaminase activity
EH233_18500	COG0546	phosphoglycolate phosphatase activity
EH233_18505	COG5002	protein histidine kinase activity
EH233_18505	COG0784	Response regulator, receiver
EH233_18510	COG0731	radical SAM domain protein
EH233_18530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EH233_18535	COG0492	ferredoxin-NADP+ reductase activity
EH233_18540	COG1175	transmembrane transport
EH233_18560	COG0330	HflC and HflK could
EH233_18565	COG0724	RNA recognition motif
EH233_18575	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EH233_18605	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EH233_18620	COG0589	response to stress
EH233_18645	COG1034	ATP synthesis coupled electron transport
EH233_18665	COG1122	ATPase activity
EH233_18670	COG3688	RNA-binding protein containing a PIN domain
EH233_18690	COG1372	Participates in initiation and elongation during chromosome replication
EH233_18690	COG0187	DNA topoisomerase II activity
EH233_18700	COG0515	serine threonine protein kinase
EH233_18700	COG3266	domain, Protein
EH233_18705	COG0277	FAD linked oxidase domain protein
EH233_18725	COG5001	Diguanylate cyclase
EH233_18725	COG4251	negative regulation of phosphorylation
EH233_18725	COG3706	GGDEF domain
EH233_18725	COG2203	Gaf domain
EH233_18745	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EH233_18750	COG0515	serine threonine protein kinase
EH233_18750	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_18770	COG0395	ABC-type sugar transport system, permease component
EH233_18775	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EH233_18780	COG5322	oxidoreductase activity
EH233_18790	COG0300	oxidoreductase activity
EH233_18795	COG0302	gtp cyclohydrolase
EH233_18835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH233_18850	COG1309	transcriptional regulator
EH233_18865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH233_18870	COG0250	Participates in transcription elongation, termination and antitermination
EH233_18910	COG4221	oxidoreductase activity
EH233_18980	COG1017	nitric oxide dioxygenase activity
EH233_18980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH233_18990	COG2133	pyrroloquinoline quinone binding
EH233_19030	COG1136	(ABC) transporter
EH233_19030	COG0577	efflux transmembrane transporter activity
EH233_19035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH233_19040	COG1136	(ABC) transporter
EH233_19045	COG0577	efflux transmembrane transporter activity
EH233_19045	COG1136	(ABC) transporter
EH233_19065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_19085	COG3240	lipase activity
EH233_19140	COG1022	Amp-dependent synthetase and ligase
EH233_19160	COG4251	negative regulation of phosphorylation
EH233_19160	COG2203	Gaf domain
EH233_19160	COG5001	Diguanylate cyclase
EH233_19160	COG3706	GGDEF domain
EH233_19180	COG2201	protein-glutamate methylesterase activity
EH233_19185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EH233_19215	COG5002	protein histidine kinase activity
EH233_19250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_19260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EH233_19280	COG0409	Hydrogenase expression formation protein
EH233_19345	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EH233_19350	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EH233_19355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_19360	COG0475	glutathione-regulated potassium exporter activity
EH233_19360	COG0589	response to stress
EH233_19375	COG0772	Belongs to the SEDS family
EH233_19380	COG0489	protein tyrosine kinase activity
EH233_19390	COG0408	coproporphyrinogen oxidase activity
EH233_19420	COG0848	biopolymer transport protein
EH233_19425	COG0811	peptide transport
EH233_19435	COG1132	(ABC) transporter
EH233_19450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH233_19450	COG0574	Belongs to the PEP-utilizing enzyme family
EH233_19455	COG0589	response to stress
EH233_19460	COG0826	peptidase U32
EH233_19465	COG0443	Heat shock 70 kDa protein
EH233_19515	COG0523	cobalamin synthesis protein
EH233_19525	COG0312	modulator of DNA gyrase
EH233_19550	COG2208	phosphoserine phosphatase activity
EH233_19555	COG0552	protein localization to endoplasmic reticulum
EH233_19595	COG1215	transferase activity, transferring glycosyl groups
EH233_19600	COG1215	transferase activity, transferring glycosyl groups
EH233_19630	COG1570	exodeoxyribonuclease VII activity
EH233_19635	COG0523	cobalamin synthesis protein
EH233_19650	COG0312	modulator of DNA gyrase
EH233_19655	COG3852	Histidine kinase
EH233_19660	COG1366	Belongs to the anti-sigma-factor antagonist family
EH233_19665	COG0745	RESPONSE REGULATOR receiver
EH233_19700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH233_19710	COG0539	negative regulation of cytoplasmic translation
EH233_19715	COG0412	Dienelactone hydrolase
EH233_19720	COG2188	Transcriptional regulator
EH233_19755	COG3540	Alkaline phosphatase
EH233_19760	COG3000	fatty acid hydroxylase
EH233_19760	COG0300	oxidoreductase activity
EH233_19775	COG0584	glycerophosphoryl diester phosphodiesterase
EH233_19795	COG0587	DNA-directed DNA polymerase activity
EH233_19825	COG2203	Gaf domain
EH233_19825	COG3706	GGDEF domain
EH233_19825	COG5001	Diguanylate cyclase
EH233_19825	COG4251	negative regulation of phosphorylation
EH233_19845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EH233_19865	COG1215	transferase activity, transferring glycosyl groups
EH233_19880	COG0438	transferase activity, transferring glycosyl groups
EH233_19900	COG0489	protein tyrosine kinase activity
EH233_19905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_19915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH233_19960	COG0730	response to heat
EH233_19975	COG1473	amidohydrolase
EH233_19980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EH233_20015	COG1285	pathogenesis
EH233_20020	COG0431	NADPH-dependent FMN reductase
EH233_20040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_20075	COG1695	Transcriptional regulator
EH233_20080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_20120	COG0577	efflux transmembrane transporter activity
EH233_20120	COG1136	(ABC) transporter
EH233_20130	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EH233_20135	COG2211	Major facilitator Superfamily
EH233_20140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH233_20145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH233_20150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH233_20165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_20175	COG4294	response to UV
EH233_20180	COG0443	Heat shock 70 kDa protein
EH233_20195	COG1049	propionate catabolic process, 2-methylcitrate cycle
EH233_20200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH233_20210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH233_20225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EH233_20255	COG0628	permease
EH233_20295	COG0163	prenyltransferase activity
EH233_20300	COG0557	exoribonuclease II activity
EH233_20320	COG1331	Highly conserved protein containing a thioredoxin domain
EH233_20370	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EH233_20400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EH233_20405	COG3536	Protein conserved in bacteria
EH233_20420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EH233_20425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EH233_20450	COG3546	catalase activity
EH233_20455	COG2261	transglycosylase associated protein
EH233_20460	COG4232	protein-disulfide reductase activity
EH233_20480	COG5398	heme oxygenase
EH233_20485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH233_20505	COG2327	Polysaccharide pyruvyl transferase
EH233_20510	COG0617	tRNA 3'-terminal CCA addition
EH233_20520	COG1214	PFAM Peptidase M22, glycoprotease
EH233_20525	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EH233_20550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_20555	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH233_20560	COG1027	Aspartate ammonia-lyase
EH233_20565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_20605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_20625	COG0438	transferase activity, transferring glycosyl groups
EH233_20645	COG0438	transferase activity, transferring glycosyl groups
EH233_20655	COG1845	cytochrome c oxidase, subunit III
EH233_20660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EH233_20665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH233_20690	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EH233_20695	COG2211	Major facilitator Superfamily
EH233_20700	COG2815	serine threonine protein kinase
EH233_20700	COG0515	serine threonine protein kinase
EH233_20705	COG0724	RNA recognition motif
EH233_20710	COG0010	Belongs to the arginase family
EH233_20715	COG3854	ATPases associated with a variety of cellular activities
EH233_20745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EH233_20755	COG0802	atpase or kinase
EH233_20765	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EH233_20790	COG0546	phosphoglycolate phosphatase activity
EH233_20795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH233_20810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH233_20815	COG0667	Aldo Keto reductase
EH233_20845	COG2072	flavoprotein involved in K transport
EH233_20890	COG1215	transferase activity, transferring glycosyl groups
EH233_20895	COG1132	(ABC) transporter
EH233_20905	COG0489	protein tyrosine kinase activity
EH233_20915	COG0460	homoserine dehydrogenase
EH233_20945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EH233_20950	COG0579	oxidoreductase
EH233_20955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EH233_20970	COG4245	von Willebrand factor, type A
EH233_21025	COG1032	radical SAM domain protein
EH233_21040	COG1733	regulation of RNA biosynthetic process
EH233_21060	COG0569	domain protein
EH233_21070	COG0025	NhaP-type Na H and K H
EH233_21100	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EH233_21115	COG2226	methyltransferase
EH233_21125	COG1013	pyruvate-flavodoxin oxidoreductase activity
EH233_21125	COG0674	pyruvate-flavodoxin oxidoreductase activity
EH233_21125	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EH233_21125	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EH233_21165	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EH233_21175	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EH233_21180	COG3977	Valine--pyruvate aminotransferase
EH233_21195	COG2205	protein histidine kinase activity
EH233_21200	COG2205	protein histidine kinase activity
EH233_21200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_21230	COG2205	protein histidine kinase activity
EH233_21245	COG3659	wide pore channel activity
EH233_21255	COG0515	serine threonine protein kinase
EH233_21255	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_21265	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EH233_21275	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EH233_21280	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EH233_21285	COG5002	protein histidine kinase activity
EH233_21290	COG2197	response regulator
EH233_21315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_21355	COG1649	PFAM Uncharacterised BCR, COG1649
EH233_21365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EH233_21365	COG0189	ligase activity
EH233_21390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH233_21410	COG1598	PFAM Uncharacterised protein family UPF0150
EH233_21435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EH233_21455	COG0745	RESPONSE REGULATOR receiver
EH233_21500	COG1120	ATPase activity
EH233_21540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH233_21550	COG0561	phosphatase activity
EH233_21570	COG3903	Transcriptional regulator
EH233_21570	COG2319	Wd-40 repeat
EH233_21595	COG1846	Transcriptional regulator
EH233_21625	COG0631	protein serine/threonine phosphatase activity
EH233_21660	COG3266	domain, Protein
EH233_21660	COG0515	serine threonine protein kinase
EH233_21730	COG1475	DNA binding
EH233_21735	COG1192	Involved in chromosome partitioning
EH233_21770	COG1372	Participates in initiation and elongation during chromosome replication
EH233_21770	COG0305	Participates in initiation and elongation during chromosome replication
EH233_21770	COG1372	Participates in initiation and elongation during chromosome replication
EH233_21770	COG0305	Participates in initiation and elongation during chromosome replication
EH233_21835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH233_21835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH233_21855	COG4251	negative regulation of phosphorylation
EH233_21870	COG1201	RNA secondary structure unwinding
EH233_21880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_21885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_21885	COG1116	anion transmembrane transporter activity
EH233_21895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_21905	COG0406	alpha-ribazole phosphatase activity
EH233_21910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EH233_21915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EH233_21920	COG2048	Heterodisulfide reductase, subunit B
EH233_21925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_21935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH233_21940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EH233_21975	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EH233_22035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_22035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_22170	COG0410	ABC transporter
EH233_22185	COG2082	Precorrin-8x methylmutase
EH233_22230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH233_22285	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EH233_22355	COG0668	transmembrane transport
EH233_22365	COG0745	RESPONSE REGULATOR receiver
EH233_22375	COG5002	protein histidine kinase activity
EH233_22380	COG5002	protein histidine kinase activity
EH233_22390	COG0697	spore germination
EH233_22435	COG1309	transcriptional regulator
EH233_22450	COG0577	efflux transmembrane transporter activity
EH233_22450	COG1136	(ABC) transporter
EH233_22460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH233_22485	COG0840	transmembrane signaling receptor activity
EH233_22500	COG0784	Response regulator, receiver
EH233_22510	COG0037	tRNA processing
EH233_22540	COG0439	Biotin carboxylase
EH233_22555	COG0515	serine threonine protein kinase
EH233_22565	COG2203	Gaf domain
EH233_22565	COG3706	GGDEF domain
EH233_22565	COG4251	negative regulation of phosphorylation
EH233_22565	COG5001	Diguanylate cyclase
EH233_22575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH233_22600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH233_22605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EH233_22625	COG1216	Glycosyl transferase, family 2
EH233_22630	COG3206	protein involved in exopolysaccharide biosynthesis
EH233_22630	COG0489	protein tyrosine kinase activity
EH233_22685	COG2268	Band 7 protein
EH233_22700	COG2223	nitrite transmembrane transporter activity
EH233_22710	COG0456	acetyltransferase
EH233_22720	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EH233_22720	COG0662	Cupin 2, conserved barrel domain protein
EH233_22745	COG4783	chaperone-mediated protein folding
EH233_22765	COG0667	Aldo Keto reductase
EH233_22790	COG0346	lactoylglutathione lyase activity
EH233_22795	COG0542	response to heat
EH233_22815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_22820	COG0793	Belongs to the peptidase S41A family
EH233_22830	COG0174	glutamine synthetase
EH233_22840	COG2226	methyltransferase
EH233_22860	COG0515	serine threonine protein kinase
EH233_22860	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_22865	COG1063	alcohol dehydrogenase
EH233_22905	COG0542	response to heat
EH233_22965	COG0745	RESPONSE REGULATOR receiver
EH233_22970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EH233_23000	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EH233_23005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH233_23015	COG0511	ligase activity, forming carbon-carbon bonds
EH233_23020	COG0640	Transcriptional regulator
EH233_23040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH233_23050	COG2202	Pas domain
EH233_23050	COG3920	Histidine kinase
EH233_23060	COG2205	protein histidine kinase activity
EH233_23110	COG2884	Cell division ATP-binding protein ftsE
EH233_23120	COG2197	response regulator
EH233_23170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EH233_23185	COG4636	protein conserved in cyanobacteria
EH233_23220	COG0419	ATPase involved in DNA repair
EH233_23250	COG0670	Belongs to the BI1 family
EH233_23285	COG0438	transferase activity, transferring glycosyl groups
EH233_23305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EH233_23310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH233_23315	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EH233_23355	COG1462	curli production assembly transport component CsgG
EH233_23410	COG0612	Peptidase, M16
EH233_23415	COG0612	Peptidase, M16
EH233_23430	COG0384	phenazine biosynthesis protein PhzF
EH233_23435	COG0006	proline dipeptidase activity
EH233_23455	COG0559	Belongs to the binding-protein-dependent transport system permease family
EH233_23470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EH233_23490	COG1702	phosphate starvation-inducible protein PhoH
EH233_23510	COG0095	Lipoate-protein ligase
EH233_23520	COG0542	response to heat
EH233_23545	COG0515	serine threonine protein kinase
EH233_23545	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_23570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EH233_23570	COG0784	Response regulator, receiver
EH233_23580	COG0515	serine threonine protein kinase
EH233_23580	COG2815	serine threonine protein kinase
EH233_23595	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_23610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_23650	COG1301	dicarboxylic acid transport
EH233_23665	COG1121	(ABC) transporter
EH233_23670	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH233_23670	COG3443	Belongs to the bacterial solute-binding protein 9 family
EH233_23675	COG0113	porphobilinogen synthase activity
EH233_23680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH233_23690	COG0523	cobalamin synthesis protein
EH233_23695	COG2226	methyltransferase
EH233_23755	COG3659	wide pore channel activity
EH233_23770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EH233_23810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EH233_23835	COG0701	Predicted permease
EH233_23840	COG3852	Histidine kinase
EH233_23845	COG2084	Dehydrogenase
EH233_23855	COG2203	Gaf domain
EH233_23860	COG0392	lysyltransferase activity
EH233_23880	COG0392	lysyltransferase activity
EH233_23880	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EH233_23890	COG0501	Belongs to the peptidase M48B family
EH233_23900	COG1388	LysM domain
EH233_23900	COG4942	peptidase
EH233_23905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EH233_23910	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EH233_23915	COG0123	including yeast histone deacetylase and acetoin utilization protein
EH233_23935	COG1192	Involved in chromosome partitioning
EH233_23945	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EH233_23950	COG2201	protein-glutamate methylesterase activity
EH233_23965	COG2203	Gaf domain
EH233_23965	COG0840	transmembrane signaling receptor activity
EH233_23970	COG0643	Histidine kinase
EH233_23970	COG2198	Histidine kinase
EH233_23980	COG1741	Belongs to the pirin family
EH233_23985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH233_24000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH233_24030	COG3437	response regulator, receiver
EH233_24035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH233_24035	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EH233_24060	COG0045	succinate-CoA ligase (ADP-forming) activity
EH233_24075	COG1770	oligopeptidase
EH233_24090	COG3320	Male sterility
EH233_24090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_24105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH233_24110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH233_24120	COG1032	radical SAM domain protein
EH233_24130	COG0517	IMP dehydrogenase activity
EH233_24130	COG1994	Peptidase M50
EH233_24145	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_24160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH233_24170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH233_24190	COG0438	transferase activity, transferring glycosyl groups
EH233_24190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EH233_24220	COG0515	serine threonine protein kinase
EH233_24225	COG5002	protein histidine kinase activity
EH233_24295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EH233_24305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_24330	COG1957	nucleoside hydrolase
EH233_24335	COG2197	response regulator
EH233_24340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_24345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH233_24355	COG0071	Belongs to the small heat shock protein (HSP20) family
EH233_24360	COG2076	Multidrug Resistance protein
EH233_24370	COG1131	(ABC) transporter
EH233_24380	COG0330	HflC and HflK could
EH233_24385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EH233_24395	COG1160	GTP binding
EH233_24410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EH233_24425	COG0113	porphobilinogen synthase activity
EH233_24450	COG0438	transferase activity, transferring glycosyl groups
EH233_24470	COG4783	chaperone-mediated protein folding
EH233_24475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH233_24485	COG0131	Imidazoleglycerol-phosphate dehydratase
EH233_24490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EH233_24505	COG4372	Transposase
EH233_24530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_24545	COG5635	Nacht domain
EH233_24545	COG5635	Nacht domain
EH233_24545	COG2319	Wd-40 repeat
EH233_24545	COG2319	Wd-40 repeat
EH233_24575	COG1487	ribonuclease activity
EH233_24585	COG0732	type I restriction modification DNA specificity domain
EH233_24610	COG2205	protein histidine kinase activity
EH233_24620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EH233_24630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH233_24660	COG0297	glycogen (starch) synthase activity
EH233_24670	COG2274	protein secretion by the type I secretion system
EH233_24675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH233_24685	COG2205	protein histidine kinase activity
EH233_24690	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EH233_24700	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EH233_24705	COG1942	4-Oxalocrotonate Tautomerase
EH233_24735	COG0581	inorganic phosphate transmembrane transporter activity
EH233_24740	COG0573	inorganic phosphate transmembrane transporter activity
EH233_24785	COG0601	transmembrane transport
EH233_24795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH233_24805	COG0811	peptide transport
EH233_24820	COG0616	signal peptide processing
EH233_24875	COG4974	Belongs to the 'phage' integrase family
EH233_24905	COG1475	DNA binding
EH233_24910	COG1192	Involved in chromosome partitioning
EH233_24935	COG0590	tRNA wobble adenosine to inosine editing
EH233_24940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH233_24945	COG0702	epimerase
EH233_24975	COG0745	RESPONSE REGULATOR receiver
EH233_24975	COG3706	GGDEF domain
EH233_24985	COG4191	Histidine kinase
EH233_25010	COG1982	Orn Lys Arg decarboxylase major
EH233_25025	COG0432	Pfam Uncharacterised protein family UPF0047
EH233_25090	COG0285	dihydrofolate synthase activity
EH233_25120	COG0612	Peptidase, M16
EH233_25130	COG0024	Methionine aminopeptidase
EH233_25140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_25175	COG2197	response regulator
EH233_25180	COG2205	protein histidine kinase activity
EH233_25275	COG0463	Glycosyl transferase, family 2
EH233_25280	COG1063	alcohol dehydrogenase
EH233_25285	COG2831	hemolysin activation secretion protein
EH233_25305	COG3210	domain, Protein
EH233_25340	COG0697	spore germination
EH233_25350	COG0436	Aminotransferase
EH233_25355	COG3118	belongs to the thioredoxin family
EH233_25360	COG1842	Phage shock protein A
EH233_25365	COG1842	Phage shock protein A
EH233_25400	COG0572	uridine kinase
EH233_25435	COG0686	Belongs to the AlaDH PNT family
EH233_25440	COG3639	organic phosphonate transmembrane transporter activity
EH233_25460	COG0406	alpha-ribazole phosphatase activity
EH233_25475	COG3659	wide pore channel activity
EH233_25480	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH233_25490	COG1879	ABC-type sugar transport system periplasmic component
EH233_25495	COG1609	Transcriptional regulator
EH233_25500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH233_25510	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_25520	COG0288	reversible hydration of carbon dioxide
EH233_25550	COG3659	wide pore channel activity
EH233_25555	COG1959	2 iron, 2 sulfur cluster binding
EH233_25560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH233_25565	COG0484	heat shock protein binding
EH233_25590	COG2081	HI0933 family
EH233_25610	COG2442	InterPro IPR007367
EH233_25640	COG0191	fructose-bisphosphate aldolase activity
EH233_25645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_25655	COG1979	alcohol dehydrogenase
EH233_25660	COG1309	transcriptional regulator
EH233_25670	COG0521	Mo-molybdopterin cofactor biosynthetic process
EH233_25675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EH233_25680	COG0271	Belongs to the BolA IbaG family
EH233_25695	COG4095	Psort location CytoplasmicMembrane, score
EH233_25700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH233_25725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH233_25725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH233_25755	COG0463	Glycosyl transferase, family 2
EH233_25755	COG1216	Glycosyl transferase, family 2
EH233_25760	COG2244	polysaccharide biosynthetic process
EH233_25765	COG1215	transferase activity, transferring glycosyl groups
EH233_25770	COG1215	transferase activity, transferring glycosyl groups
EH233_25775	COG0438	transferase activity, transferring glycosyl groups
EH233_25790	COG5039	Polysaccharide pyruvyl transferase
EH233_25795	COG2244	polysaccharide biosynthetic process
EH233_25800	COG0438	transferase activity, transferring glycosyl groups
EH233_25805	COG1216	Glycosyl transferase, family 2
EH233_25805	COG0463	Glycosyl transferase, family 2
EH233_25810	COG1216	Glycosyl transferase, family 2
EH233_25810	COG0463	Glycosyl transferase, family 2
EH233_25815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EH233_25830	COG0438	transferase activity, transferring glycosyl groups
EH233_25835	COG0438	transferase activity, transferring glycosyl groups
EH233_25845	COG0515	serine threonine protein kinase
EH233_25845	COG2815	serine threonine protein kinase
EH233_25855	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EH233_25880	COG0076	glutamate decarboxylase activity
EH233_25910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_25915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH233_25920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_25920	COG1116	anion transmembrane transporter activity
EH233_25925	COG1116	anion transmembrane transporter activity
EH233_25940	COG2205	protein histidine kinase activity
EH233_25955	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EH233_25970	COG0129	dihydroxy-acid dehydratase activity
EH233_26080	COG5002	protein histidine kinase activity
EH233_26080	COG0784	Response regulator, receiver
EH233_26080	COG2205	protein histidine kinase activity
EH233_26105	COG0583	DNA-binding transcription factor activity
EH233_26120	COG1252	NADH dehydrogenase
EH233_26140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_26150	COG0606	chelatase, subunit chli
EH233_26155	COG0537	adenosine 5'-monophosphoramidase activity
EH233_26185	COG0438	transferase activity, transferring glycosyl groups
EH233_26205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_26205	COG0426	domain, Protein
EH233_26215	COG0426	domain, Protein
EH233_26215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_26230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_26235	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EH233_26255	COG0438	transferase activity, transferring glycosyl groups
EH233_26280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH233_26310	COG0713	ATP synthesis coupled electron transport
EH233_26315	COG0839	Belongs to the complex I subunit 6 family
EH233_26330	COG0372	Belongs to the citrate synthase family
EH233_26335	COG2062	phosphohistidine phosphatase, SixA
EH233_26345	COG5001	Diguanylate cyclase
EH233_26370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EH233_26415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EH233_26440	COG1881	PFAM PEBP family protein
EH233_26445	COG2319	Wd-40 repeat
EH233_26445	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_26470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH233_26475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH233_26530	COG2135	peptidase activity
EH233_26535	COG0625	glutathione transferase activity
EH233_26555	COG5592	hemerythrin HHE cation binding domain
EH233_26565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH233_26590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH233_26595	COG1120	ATPase activity
EH233_26605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH233_26610	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EH233_26625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EH233_26640	COG1271	oxidase subunit
EH233_26645	COG1294	oxidase, subunit
EH233_26655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_26665	COG3259	Nickel-dependent hydrogenase
EH233_26680	COG0045	succinate-CoA ligase (ADP-forming) activity
EH233_26680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH233_26680	COG1042	CoA-binding domain protein
EH233_26690	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EH233_26695	COG4221	oxidoreductase activity
EH233_26700	COG2226	methyltransferase
EH233_26715	COG1657	PFAM Prenyltransferase squalene oxidase
EH233_26735	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_26745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_26750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_26785	COG4942	peptidase
EH233_26790	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EH233_26790	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EH233_26800	COG0385	Bile acid
EH233_26815	COG2204	response regulator
EH233_26840	COG0300	oxidoreductase activity
EH233_26875	COG2202	Pas domain
EH233_26875	COG2205	protein histidine kinase activity
EH233_26880	COG0784	Response regulator, receiver
EH233_26885	COG4251	negative regulation of phosphorylation
EH233_26890	COG1230	cation diffusion facilitator family transporter
EH233_26915	COG0151	Belongs to the GarS family
EH233_26920	COG5002	protein histidine kinase activity
EH233_26925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH233_26930	COG2166	iron-sulfur cluster assembly
EH233_26970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_26985	COG5002	protein histidine kinase activity
EH233_26985	COG2198	Histidine kinase
EH233_26985	COG0784	Response regulator, receiver
EH233_27020	COG1187	pseudouridine synthase activity
EH233_27035	COG0515	serine threonine protein kinase
EH233_27090	COG1136	(ABC) transporter
EH233_27095	COG0501	Belongs to the peptidase M48B family
EH233_27140	COG4245	von Willebrand factor, type A
EH233_27150	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EH233_27195	COG0484	heat shock protein binding
EH233_27220	COG2319	Wd-40 repeat
EH233_27220	COG3903	Transcriptional regulator
EH233_27230	COG0450	alkyl hydroperoxide reductase
EH233_27235	COG2304	oxidoreductase activity
EH233_27250	COG0438	transferase activity, transferring glycosyl groups
EH233_27295	COG0741	lytic transglycosylase activity
EH233_27345	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_27345	COG0515	serine threonine protein kinase
EH233_27350	COG1136	(ABC) transporter
EH233_27360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH233_27395	COG0693	protein deglycase activity
EH233_27470	COG0501	Belongs to the peptidase M48B family
EH233_27505	COG0824	Thioesterase
EH233_27510	COG0564	pseudouridine synthase activity
EH233_27540	COG1120	ATPase activity
EH233_27545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH233_27550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH233_27580	COG1858	cytochrome C peroxidase
EH233_27590	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EH233_27615	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EH233_27630	COG4243	Vitamin k epoxide reductase
EH233_27635	COG0434	BtpA family
EH233_27645	COG0513	Belongs to the DEAD box helicase family
EH233_27660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_27685	COG2319	Wd-40 repeat
EH233_27685	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_27705	COG3321	synthase
EH233_27705	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_27705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH233_27705	COG0318	PFAM AMP-dependent synthetase and ligase
EH233_27705	COG0300	oxidoreductase activity
EH233_27725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EH233_27730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_27735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EH233_27740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_27755	COG0673	inositol 2-dehydrogenase activity
EH233_27770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EH233_27780	COG1228	amidohydrolase
EH233_27790	COG0233	cytoplasmic translational termination
EH233_27850	COG5634	Uncharacterized conserved protein (DUF2278)
EH233_27855	COG0242	peptide deformylase activity
EH233_27865	COG2203	Gaf domain
EH233_27865	COG3706	GGDEF domain
EH233_27865	COG4251	negative regulation of phosphorylation
EH233_27865	COG5001	Diguanylate cyclase
EH233_27875	COG0456	acetyltransferase
EH233_27880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EH233_27880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EH233_27885	COG0583	DNA-binding transcription factor activity
EH233_27890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH233_27905	COG0784	Response regulator, receiver
EH233_27915	COG1132	(ABC) transporter
EH233_27930	COG1940	carbohydrate kinase activity
EH233_27950	COG1253	flavin adenine dinucleotide binding
EH233_27960	COG0673	inositol 2-dehydrogenase activity
EH233_27965	COG0586	Pfam SNARE associated Golgi protein
EH233_27980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH233_27985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EH233_28030	COG1429	ligase activity, forming nitrogen-metal bonds
EH233_28035	COG0515	serine threonine protein kinase
EH233_28035	COG3266	domain, Protein
EH233_28045	COG0515	serine threonine protein kinase
EH233_28045	COG3266	domain, Protein
EH233_28065	COG0475	glutathione-regulated potassium exporter activity
EH233_28065	COG0589	response to stress
EH233_28070	COG1234	tRNA 3'-trailer cleavage
EH233_28080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EH233_28120	COG5398	heme oxygenase
EH233_28130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH233_28135	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_28140	COG3118	belongs to the thioredoxin family
EH233_28160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH233_28165	COG2197	response regulator
EH233_28205	COG1845	cytochrome c oxidase, subunit III
EH233_28215	COG0306	phosphate transporter
EH233_28220	COG2226	methyltransferase
EH233_28240	COG0758	DNA mediated transformation
EH233_28240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH233_28250	COG0358	DNA primase activity
EH233_28255	COG1446	asparaginase
EH233_28295	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_28320	COG2319	Wd-40 repeat
EH233_28320	COG1672	PFAM Archaeal ATPase
EH233_28335	COG0438	transferase activity, transferring glycosyl groups
EH233_28345	COG0343	queuine tRNA-ribosyltransferase activity
EH233_28375	COG0470	DNA polymerase III
EH233_28390	COG3335	DDE superfamily endonuclease
EH233_28405	COG0776	regulation of translation
EH233_28440	COG2373	Large extracellular alpha-helical protein
EH233_28445	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EH233_28475	COG1845	cytochrome c oxidase, subunit III
EH233_28485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH233_28530	COG1266	CAAX protease self-immunity
EH233_28580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH233_28580	COG0512	Glutamine amidotransferase of anthranilate synthase
EH233_28585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EH233_28615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH233_28620	COG3903	Transcriptional regulator
EH233_28620	COG2319	Wd-40 repeat
EH233_28630	COG0798	PFAM Bile acid sodium symporter
EH233_28635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EH233_28645	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EH233_28650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EH233_28715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH233_28725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_28725	COG0426	domain, Protein
EH233_28730	COG0426	domain, Protein
EH233_28730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_28740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH233_28775	COG4948	Mandelate Racemase Muconate Lactonizing
EH233_28785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EH233_28815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH233_28815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH233_28845	COG0587	DNA-directed DNA polymerase activity
EH233_28860	COG1121	(ABC) transporter
EH233_28890	COG2319	Wd-40 repeat
EH233_28890	COG5635	Nacht domain
EH233_28930	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EH233_28970	COG0640	Transcriptional regulator
EH233_29015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH233_29045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH233_29070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_29080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH233_29115	COG0730	response to heat
EH233_29190	COG3385	transposase activity