locus-tag	class	description
acsn021_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
acsn021_00020	COG0592	DNA-directed DNA polymerase activity
acsn021_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
acsn021_00050	COG0187	DNA topoisomerase II activity
acsn021_00060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
acsn021_00130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
acsn021_00140	COG0745	RESPONSE REGULATOR receiver
acsn021_00150	COG3850	Histidine kinase
acsn021_00150	COG5002	protein histidine kinase activity
acsn021_00160	COG1132	(ABC) transporter
acsn021_00170	COG1132	(ABC) transporter
acsn021_00180	COG2357	RelA SpoT domain protein
acsn021_00190	COG0539	negative regulation of cytoplasmic translation
acsn021_00200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
acsn021_00230	COG1362	aminopeptidase activity
acsn021_00240	COG3279	Response regulator of the LytR AlgR family
acsn021_00310	COG1609	Transcriptional regulator
acsn021_00330	COG0058	SHG alpha-glucan phosphorylase activity
acsn021_00350	COG1175	transmembrane transport
acsn021_00360	COG3833	ABC-type maltose transport systems, permease component
acsn021_00530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
acsn021_00540	COG0537	adenosine 5'-monophosphoramidase activity
acsn021_00570	COG0457	Tetratricopeptide repeat
acsn021_00570	COG0705	Rhomboid family
acsn021_00580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
acsn021_00590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
acsn021_00610	COG1846	Transcriptional regulator
acsn021_00630	COG0617	tRNA 3'-terminal CCA addition
acsn021_00670	COG4466	Protein conserved in bacteria
acsn021_00680	COG1388	LysM domain
acsn021_00680	COG0791	NLP P60 protein
acsn021_00700	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
acsn021_00720	COG1181	Belongs to the D-alanine--D-alanine ligase family
acsn021_00730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
acsn021_00770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
acsn021_00780	COG1876	peptidase activity
acsn021_00790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
acsn021_00800	COG0058	SHG alpha-glucan phosphorylase activity
acsn021_00810	COG0714	Associated with various cellular activities
acsn021_00850	COG0584	glycerophosphoryl diester phosphodiesterase
acsn021_00900	COG4608	Belongs to the ABC transporter superfamily
acsn021_00910	COG0444	Belongs to the ABC transporter superfamily
acsn021_00920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_00930	COG0601	transmembrane transport
acsn021_00940	COG4166	transmembrane transport
acsn021_00960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
acsn021_01080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
acsn021_01090	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
acsn021_01100	COG0017	Asparaginyl-tRNA synthetase
acsn021_01110	COG1595	DNA-templated transcription, initiation
acsn021_01130	COG0577	efflux transmembrane transporter activity
acsn021_01140	COG1136	(ABC) transporter
acsn021_01140	COG0577	efflux transmembrane transporter activity
acsn021_01190	COG3279	Response regulator of the LytR AlgR family
acsn021_01210	COG0183	Belongs to the thiolase family
acsn021_01220	COG4689	acetoacetate decarboxylase
acsn021_01230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
acsn021_01260	COG2188	Transcriptional regulator
acsn021_01280	COG2207	Transcriptional regulator
acsn021_01280	COG3708	Transcriptional regulator
acsn021_01300	COG1278	Cold shock
acsn021_01320	COG1653	transport
acsn021_01330	COG4209	transmembrane transport
acsn021_01340	COG0395	ABC-type sugar transport system, permease component
acsn021_01360	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_01390	COG1486	melibiose metabolic process
acsn021_01400	COG1609	Transcriptional regulator
acsn021_01400	COG2207	Transcriptional regulator
acsn021_01410	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_01460	COG3328	transposase activity
acsn021_01520	COG0778	Nitroreductase
acsn021_01660	COG3299	homolog of phage Mu protein gp47
acsn021_01760	COG4717	serine-type aminopeptidase activity
acsn021_01770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
acsn021_01880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
acsn021_01890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
acsn021_01910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
acsn021_01940	COG2088	sporulation resulting in formation of a cellular spore
acsn021_01970	COG0193	aminoacyl-tRNA hydrolase activity
acsn021_01980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
acsn021_01990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
acsn021_02020	COG0671	phosphoesterase, PA-phosphatase related
acsn021_02030	COG4555	ABC transporter
acsn021_02040	COG1668	transmembrane transport
acsn021_02060	COG2002	toxin-antitoxin pair type II binding
acsn021_02070	COG3956	TIGRFAM MazG family protein
acsn021_02080	COG0776	regulation of translation
acsn021_02090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
acsn021_02120	COG2208	phosphoserine phosphatase activity
acsn021_02130	COG0037	tRNA processing
acsn021_02140	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
acsn021_02150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
acsn021_02160	COG3103	Sh3 type 3 domain protein
acsn021_02160	COG0366	Alpha amylase catalytic
acsn021_02200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
acsn021_02210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
acsn021_02220	COG2176	DNA-directed DNA polymerase activity
acsn021_02240	COG2720	vancomycin resistance protein
acsn021_02250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
acsn021_02260	COG1522	sequence-specific DNA binding
acsn021_02270	COG0436	Aminotransferase
acsn021_02300	COG5002	protein histidine kinase activity
acsn021_02310	COG0745	RESPONSE REGULATOR receiver
acsn021_02320	COG1193	negative regulation of DNA recombination
acsn021_02650	COG2207	Transcriptional regulator
acsn021_02670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_02690	COG0716	FMN binding
acsn021_02700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
acsn021_02730	COG0640	Transcriptional regulator
acsn021_02740	COG2217	Heavy metal translocating P-type atpase
acsn021_02750	COG0745	RESPONSE REGULATOR receiver
acsn021_02760	COG5002	protein histidine kinase activity
acsn021_02800	COG1193	negative regulation of DNA recombination
acsn021_02820	COG3693	PFAM glycoside hydrolase, family 10
acsn021_02820	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_02820	COG2382	esterase
acsn021_02840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
acsn021_02860	COG5520	Belongs to the glycosyl hydrolase 30 family
acsn021_02870	COG2508	Transcriptional regulator
acsn021_02890	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_02960	COG4555	ABC transporter
acsn021_03100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
acsn021_03100	COG0723	plastoquinol--plastocyanin reductase activity
acsn021_03150	COG3546	catalase activity
acsn021_03180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
acsn021_03210	COG0574	Belongs to the PEP-utilizing enzyme family
acsn021_03210	COG3848	Pyruvate phosphate dikinase
acsn021_03240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
acsn021_03250	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_03260	COG1342	Belongs to the UPF0251 family
acsn021_03280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
acsn021_03300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
acsn021_03310	COG1280	lysine exporter protein (LysE YggA)
acsn021_03320	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
acsn021_03330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
acsn021_03350	COG4260	virion core protein, lumpy skin disease virus
acsn021_03370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
acsn021_03380	COG1842	Phage shock protein A
acsn021_03400	COG1609	Transcriptional regulator
acsn021_03410	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
acsn021_03410	COG0116	Belongs to the methyltransferase superfamily
acsn021_03420	COG0051	transcription antitermination factor activity, RNA binding
acsn021_03430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
acsn021_03440	COG0088	Forms part of the polypeptide exit tunnel
acsn021_03450	COG0089	rRNA binding
acsn021_03460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
acsn021_03470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
acsn021_03480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
acsn021_03490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
acsn021_03500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
acsn021_03510	COG0255	Belongs to the universal ribosomal protein uL29 family
acsn021_03520	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
acsn021_03530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
acsn021_03540	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
acsn021_03550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
acsn021_03560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
acsn021_03570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
acsn021_03580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
acsn021_03590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
acsn021_03600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
acsn021_03610	COG1841	ribosomal large subunit assembly
acsn021_03620	COG0200	Binds to the 23S rRNA
acsn021_03630	COG0201	protein transport
acsn021_03670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
acsn021_03680	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
acsn021_03690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
acsn021_03700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
acsn021_03710	COG0202	RNA polymerase activity
acsn021_03720	COG0203	ribosomal protein L17
acsn021_03730	COG2207	Transcriptional regulator
acsn021_03740	COG2190	(PTS) system
acsn021_03740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_03740	COG1263	PTS System
acsn021_03760	COG1122	ATPase activity
acsn021_03770	COG1122	ATPase activity
acsn021_03780	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
acsn021_03800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
acsn021_03810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
acsn021_03930	COG4974	Belongs to the 'phage' integrase family
acsn021_04010	COG5433	transposase activity
acsn021_04020	COG5433	transposase activity
acsn021_04040	COG5484	DNA packaging
acsn021_04040	COG3728	DNA packaging
acsn021_04180	COG2378	regulation of single-species biofilm formation
acsn021_04230	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_04230	COG3693	PFAM glycoside hydrolase, family 10
acsn021_04230	COG2382	esterase
acsn021_04240	COG3344	reverse transcriptase
acsn021_04250	COG3853	Toxic anion resistance protein (TelA)
acsn021_04270	COG1609	Transcriptional regulator
acsn021_04290	COG4209	transmembrane transport
acsn021_04300	COG0395	ABC-type sugar transport system, permease component
acsn021_04310	COG1501	Belongs to the glycosyl hydrolase 31 family
acsn021_04320	COG0366	Alpha amylase catalytic
acsn021_04340	COG1595	DNA-templated transcription, initiation
acsn021_04400	COG0534	Mate efflux family protein
acsn021_04420	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_04430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
acsn021_04440	COG3842	ATPase activity
acsn021_04450	COG2508	Transcriptional regulator
acsn021_04460	COG2884	Cell division ATP-binding protein ftsE
acsn021_04470	COG2177	Part of the ABC transporter FtsEX involved in
acsn021_04480	COG1196	nuclear chromosome segregation
acsn021_04480	COG0741	lytic transglycosylase activity
acsn021_04480	COG0739	heme binding
acsn021_04490	COG0793	Belongs to the peptidase S41A family
acsn021_04520	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
acsn021_04630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
acsn021_04680	COG3843	relaxase mobilization nuclease domain protein
acsn021_04710	COG0514	ATP-dependent DNA helicase (RecQ)
acsn021_04770	COG1819	glycosyl
acsn021_04790	COG3711	transcriptional antiterminator
acsn021_04800	COG2190	(PTS) system
acsn021_04800	COG1263	PTS System
acsn021_04800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_04810	COG2723	6-phospho-beta-galactosidase activity
acsn021_04840	COG2205	protein histidine kinase activity
acsn021_04870	COG1879	ABC-type sugar transport system periplasmic component
acsn021_04890	COG1349	DNA-binding transcription factor activity
acsn021_04910	COG0813	purine-nucleoside phosphorylase activity
acsn021_04920	COG1744	ABC transporter substrate-binding protein PnrA-like
acsn021_04930	COG3845	ABC transporter
acsn021_04940	COG4603	Belongs to the binding-protein-dependent transport system permease family
acsn021_04950	COG1079	Belongs to the binding-protein-dependent transport system permease family
acsn021_04960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
acsn021_04970	COG0187	DNA topoisomerase II activity
acsn021_05030	COG1256	bacterial-type flagellum assembly
acsn021_05030	COG4786	Flagellar basal body rod
acsn021_05040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
acsn021_05050	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
acsn021_05060	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
acsn021_05070	COG1334	flagellar protein FlaG
acsn021_05080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
acsn021_05090	COG1516	flagellar protein fliS
acsn021_05110	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
acsn021_05150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
acsn021_05170	COG0457	Tetratricopeptide repeat
acsn021_05170	COG0463	Glycosyl transferase, family 2
acsn021_05200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
acsn021_05260	COG1216	Glycosyl transferase, family 2
acsn021_05320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
acsn021_05330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
acsn021_05340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
acsn021_05370	COG0457	Tetratricopeptide repeat
acsn021_05370	COG0463	Glycosyl transferase, family 2
acsn021_05380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
acsn021_05400	COG0504	CTP synthase activity
acsn021_05410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
acsn021_05420	COG0322	excinuclease ABC activity
acsn021_05430	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
acsn021_05440	COG1940	carbohydrate kinase activity
acsn021_05450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
acsn021_05460	COG1660	Displays ATPase and GTPase activities
acsn021_05470	COG1481	regulation of sporulation
acsn021_05480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
acsn021_05530	COG0745	RESPONSE REGULATOR receiver
acsn021_05540	COG0745	RESPONSE REGULATOR receiver
acsn021_05580	COG1950	PFAM Membrane protein of
acsn021_05610	COG1132	(ABC) transporter
acsn021_05620	COG0561	phosphatase activity
acsn021_05630	COG1595	DNA-templated transcription, initiation
acsn021_05670	COG1489	DNA binding
acsn021_05690	COG0438	transferase activity, transferring glycosyl groups
acsn021_05720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
acsn021_05750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
acsn021_05760	COG1970	mechanosensitive ion channel activity
acsn021_05770	COG1376	ErfK ybiS ycfS ynhG family protein
acsn021_05790	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
acsn021_05860	COG4209	transmembrane transport
acsn021_05870	COG0395	ABC-type sugar transport system, permease component
acsn021_05880	COG0745	RESPONSE REGULATOR receiver
acsn021_05930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
acsn021_05940	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
acsn021_05950	COG1160	GTP binding
acsn021_05960	COG1027	Aspartate ammonia-lyase
acsn021_06340	COG3764	Sortase (surface protein transpeptidase)
acsn021_06410	COG0242	peptide deformylase activity
acsn021_06850	COG0352	thiamine-phosphate diphosphorylase activity
acsn021_06860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
acsn021_06870	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
acsn021_06880	COG0351	phosphomethylpyrimidine kinase
acsn021_06880	COG0352	thiamine-phosphate diphosphorylase activity
acsn021_06900	COG1653	transport
acsn021_06910	COG1175	transmembrane transport
acsn021_06920	COG0395	ABC-type sugar transport system, permease component
acsn021_06930	COG0745	RESPONSE REGULATOR receiver
acsn021_06940	COG2205	protein histidine kinase activity
acsn021_06950	COG0306	phosphate transporter
acsn021_06970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
acsn021_06980	COG0569	domain protein
acsn021_07010	COG0714	Associated with various cellular activities
acsn021_07040	COG0628	permease
acsn021_07050	COG1136	(ABC) transporter
acsn021_07080	COG0577	efflux transmembrane transporter activity
acsn021_07110	COG0667	Aldo Keto reductase
acsn021_07120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
acsn021_07130	COG0210	DNA helicase
acsn021_07140	COG3906	Belongs to the UPF0473 family
acsn021_07170	COG1597	lipid kinase activity
acsn021_07210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
acsn021_07230	COG1381	Involved in DNA repair and RecF pathway recombination
acsn021_07250	COG0423	glycine-tRNA ligase activity
acsn021_07260	COG0574	Belongs to the PEP-utilizing enzyme family
acsn021_07260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
acsn021_07280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
acsn021_07290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
acsn021_07290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
acsn021_07350	COG1396	sequence-specific DNA binding
acsn021_07390	COG0395	ABC-type sugar transport system, permease component
acsn021_07440	COG0395	ABC-type sugar transport system, permease component
acsn021_07480	COG4753	response regulator
acsn021_07480	COG2207	Transcriptional regulator
acsn021_07540	COG1316	TRANSCRIPTIONal
acsn021_07560	COG0726	polysaccharide deacetylase
acsn021_07660	COG1136	(ABC) transporter
acsn021_07690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
acsn021_07700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
acsn021_07730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_07810	COG2375	cellular response to nickel ion
acsn021_07810	COG1132	(ABC) transporter
acsn021_07820	COG1132	(ABC) transporter
acsn021_07840	COG2207	Transcriptional regulator
acsn021_07840	COG4753	response regulator
acsn021_07880	COG1959	2 iron, 2 sulfur cluster binding
acsn021_07900	COG4977	sequence-specific DNA binding
acsn021_07940	COG1874	Beta-galactosidase
acsn021_07950	COG1733	regulation of RNA biosynthetic process
acsn021_07970	COG2207	Transcriptional regulator
acsn021_07970	COG1609	Transcriptional regulator
acsn021_08190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
acsn021_08210	COG1447	Phosphotransferase system cellobiose-specific component IIA
acsn021_08230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
acsn021_08240	COG3250	beta-galactosidase activity
acsn021_08250	COG3711	transcriptional antiterminator
acsn021_08250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
acsn021_08260	COG3275	phosphorelay sensor kinase activity
acsn021_08270	COG4209	transmembrane transport
acsn021_08280	COG0395	ABC-type sugar transport system, permease component
acsn021_08300	COG2207	Transcriptional regulator
acsn021_08300	COG4753	response regulator
acsn021_08340	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_08360	COG0840	transmembrane signaling receptor activity
acsn021_08370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
acsn021_08370	COG0473	3-isopropylmalate dehydrogenase activity
acsn021_08390	COG2721	sulfolactate sulfo-lyase activity
acsn021_08400	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_08420	COG3870	Protein conserved in bacteria
acsn021_08440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
acsn021_08450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
acsn021_08460	COG3437	response regulator, receiver
acsn021_08460	COG0784	Response regulator, receiver
acsn021_08480	COG2195	Cleaves the N-terminal amino acid of tripeptides
acsn021_08490	COG1522	sequence-specific DNA binding
acsn021_08500	COG1027	Aspartate ammonia-lyase
acsn021_08510	COG0586	Pfam SNARE associated Golgi protein
acsn021_08550	COG4124	Belongs to the glycosyl hydrolase 26 family
acsn021_08560	COG0534	Mate efflux family protein
acsn021_08620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
acsn021_08690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
acsn021_08710	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
acsn021_08720	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_08740	COG3254	rhamnose metabolic process
acsn021_08760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
acsn021_08770	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
acsn021_08800	COG0534	Mate efflux family protein
acsn021_08830	COG3773	Cell wall hydrolase
acsn021_08850	COG0488	(ABC) transporter
acsn021_08890	COG1979	alcohol dehydrogenase
acsn021_08910	COG2873	o-acetylhomoserine
acsn021_08920	COG1959	2 iron, 2 sulfur cluster binding
acsn021_08930	COG1073	alpha beta
acsn021_08950	COG0295	cytidine deaminase activity
acsn021_08970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
acsn021_08990	COG1045	serine acetyltransferase
acsn021_09000	COG0215	cysteine-tRNA ligase activity
acsn021_09020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
acsn021_09120	COG3576	pyridoxamine 5-phosphate
acsn021_09160	COG0232	Belongs to the dGTPase family. Type 2 subfamily
acsn021_09170	COG0358	DNA primase activity
acsn021_09180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
acsn021_09190	COG2384	SAM-dependent methyltransferase
acsn021_09200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
acsn021_09280	COG1131	(ABC) transporter
acsn021_09310	COG3773	Cell wall hydrolase
acsn021_09320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
acsn021_09340	COG1216	Glycosyl transferase, family 2
acsn021_09410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
acsn021_09420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
acsn021_09440	COG1216	Glycosyl transferase, family 2
acsn021_09480	COG1682	transport, permease protein
acsn021_09500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
acsn021_09510	COG1216	Glycosyl transferase, family 2
acsn021_09510	COG0438	transferase activity, transferring glycosyl groups
acsn021_09520	COG0438	transferase activity, transferring glycosyl groups
acsn021_09540	COG1696	Membrane protein involved in D-alanine export
acsn021_09620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
acsn021_09630	COG0662	Cupin 2, conserved barrel domain protein
acsn021_09630	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
acsn021_09640	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
acsn021_09670	COG0628	permease
acsn021_09740	COG0438	transferase activity, transferring glycosyl groups
acsn021_09840	COG0765	amino acid transport
acsn021_09850	COG0765	amino acid transport
acsn021_09860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
acsn021_09870	COG1126	abc transporter atp-binding protein
acsn021_09910	COG1691	(AIR) carboxylase
acsn021_09920	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
acsn021_09940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
acsn021_09950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
acsn021_09960	COG1116	anion transmembrane transporter activity
acsn021_10000	COG1217	gtp-binding protein TYPA
acsn021_10030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
acsn021_10040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
acsn021_10060	COG1396	sequence-specific DNA binding
acsn021_10130	COG0840	transmembrane signaling receptor activity
acsn021_10140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
acsn021_10150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
acsn021_10150	COG0072	phenylalanine-tRNA ligase activity
acsn021_10200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
acsn021_10220	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
acsn021_10230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
acsn021_10240	COG0151	Belongs to the GarS family
acsn021_10280	COG3880	PFAM UvrB UvrC protein
acsn021_10290	COG3869	Catalyzes the specific phosphorylation of arginine residues in
acsn021_10300	COG0542	response to heat
acsn021_10320	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
acsn021_10440	COG0714	Associated with various cellular activities
acsn021_10450	COG0343	queuine tRNA-ribosyltransferase activity
acsn021_10460	COG1862	Preprotein translocase
acsn021_10470	COG0613	PHP domain protein
acsn021_10500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
acsn021_10510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
acsn021_10510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
acsn021_10520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
acsn021_10520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
acsn021_10530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
acsn021_10540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
acsn021_10550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
acsn021_10560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
acsn021_10580	COG0124	histidyl-tRNA synthetase
acsn021_10600	COG1362	aminopeptidase activity
acsn021_10620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
acsn021_10640	COG3326	Membrane
acsn021_10650	COG1396	sequence-specific DNA binding
acsn021_10710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
acsn021_10750	COG1162	GTPase activity
acsn021_10800	COG0531	amino acid
acsn021_10810	COG2226	methyltransferase
acsn021_10830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
acsn021_10840	COG1192	Involved in chromosome partitioning
acsn021_10850	COG1475	DNA binding
acsn021_11260	COG2003	Belongs to the UPF0758 family
acsn021_11340	COG0270	DNA (cytosine-5-)-methyltransferase activity
acsn021_11580	COG1598	PFAM Uncharacterised protein family UPF0150
acsn021_11630	COG3328	transposase activity
acsn021_11740	COG1396	sequence-specific DNA binding
acsn021_11810	COG1228	amidohydrolase
acsn021_11820	COG3279	Response regulator of the LytR AlgR family
acsn021_11840	COG3706	GGDEF domain
acsn021_11850	COG1396	sequence-specific DNA binding
acsn021_11860	COG1396	sequence-specific DNA binding
acsn021_11870	COG1528	Iron-storage protein
acsn021_11900	COG4120	Belongs to the binding-protein-dependent transport system permease family
acsn021_11910	COG1116	anion transmembrane transporter activity
acsn021_11970	COG0436	Aminotransferase
acsn021_12000	COG0017	Asparaginyl-tRNA synthetase
acsn021_12010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
acsn021_12020	COG0154	amidase activity
acsn021_12030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
acsn021_12050	COG0070	glutamate synthase
acsn021_12050	COG0069	glutamate synthase activity
acsn021_12050	COG0067	glutamate synthase
acsn021_12060	COG0493	'glutamate synthase
acsn021_12070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
acsn021_12150	COG0551	DNA topoisomerase type I activity
acsn021_12150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
acsn021_12170	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_12210	COG4209	transmembrane transport
acsn021_12220	COG0395	ABC-type sugar transport system, permease component
acsn021_12250	COG1956	GAF domain-containing protein
acsn021_12270	COG1773	rubredoxin
acsn021_12280	COG0840	transmembrane signaling receptor activity
acsn021_12300	COG2205	protein histidine kinase activity
acsn021_12310	COG0745	RESPONSE REGULATOR receiver
acsn021_12390	COG0124	histidyl-tRNA synthetase
acsn021_12420	COG1959	2 iron, 2 sulfur cluster binding
acsn021_12500	COG2205	protein histidine kinase activity
acsn021_12540	COG1331	Highly conserved protein containing a thioredoxin domain
acsn021_12560	COG2094	Belongs to the DNA glycosylase MPG family
acsn021_12630	COG0384	phenazine biosynthesis protein PhzF
acsn021_12660	COG0789	Transcriptional regulator
acsn021_12690	COG2378	regulation of single-species biofilm formation
acsn021_12700	COG3340	Belongs to the peptidase S51 family
acsn021_12760	COG0646	methionine synthase
acsn021_12760	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
acsn021_12780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
acsn021_12790	COG0646	methionine synthase
acsn021_12790	COG1410	methionine synthase
acsn021_12800	COG1846	Transcriptional regulator
acsn021_12820	COG1132	(ABC) transporter
acsn021_12840	COG2059	Chromate
acsn021_12860	COG0583	DNA-binding transcription factor activity
acsn021_12870	COG0789	Transcriptional regulator
acsn021_12880	COG0561	phosphatase activity
acsn021_12890	COG0534	Mate efflux family protein
acsn021_12970	COG1132	(ABC) transporter
acsn021_13050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_13110	COG1136	(ABC) transporter
acsn021_13110	COG0577	efflux transmembrane transporter activity
acsn021_13180	COG0535	radical SAM domain protein
acsn021_13210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
acsn021_13260	COG4496	protein, YerC YecD
acsn021_13270	COG3976	FMN-binding domain protein
acsn021_13270	COG1053	succinate dehydrogenase
acsn021_13270	COG0431	NADPH-dependent FMN reductase
acsn021_13280	COG0656	L-ascorbic acid biosynthetic process
acsn021_13310	COG1131	(ABC) transporter
acsn021_13320	COG1695	Transcriptional regulator
acsn021_13330	COG0154	amidase activity
acsn021_13340	COG1132	(ABC) transporter
acsn021_13350	COG4447	cellulose binding
acsn021_13350	COG5297	Belongs to the glycosyl hydrolase family 6
acsn021_13370	COG2205	protein histidine kinase activity
acsn021_13380	COG0745	RESPONSE REGULATOR receiver
acsn021_13400	COG0640	Transcriptional regulator
acsn021_13420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
acsn021_13480	COG0443	Heat shock 70 kDa protein
acsn021_13490	COG0443	Heat shock 70 kDa protein
acsn021_13500	COG0443	Heat shock 70 kDa protein
acsn021_13580	COG0534	Mate efflux family protein
acsn021_13590	COG4977	sequence-specific DNA binding
acsn021_13610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_13620	COG0444	Belongs to the ABC transporter superfamily
acsn021_13650	COG1132	(ABC) transporter
acsn021_13650	COG2375	cellular response to nickel ion
acsn021_13660	COG1132	(ABC) transporter
acsn021_13810	COG1573	uracil-dna glycosylase
acsn021_13830	COG0366	Alpha amylase catalytic
acsn021_13840	COG1846	Transcriptional regulator
acsn021_13850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
acsn021_13890	COG1136	(ABC) transporter
acsn021_13910	COG0577	efflux transmembrane transporter activity
acsn021_13910	COG1136	(ABC) transporter
acsn021_13920	COG3850	Histidine kinase
acsn021_13920	COG5002	protein histidine kinase activity
acsn021_13930	COG0745	RESPONSE REGULATOR receiver
acsn021_13940	COG1595	DNA-templated transcription, initiation
acsn021_13970	COG3695	enzyme binding
acsn021_14000	COG3328	transposase activity
acsn021_14010	COG0693	protein deglycase activity
acsn021_14020	COG0561	phosphatase activity
acsn021_14050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_14060	COG0601	transmembrane transport
acsn021_14110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
acsn021_14120	COG0709	Synthesizes selenophosphate from selenide and ATP
acsn021_14160	COG3608	succinylglutamate desuccinylase aspartoacylase
acsn021_14160	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
acsn021_14180	COG1611	Belongs to the LOG family
acsn021_14190	COG0583	DNA-binding transcription factor activity
acsn021_14250	COG4912	Dna alkylation repair
acsn021_14260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
acsn021_14280	COG1131	(ABC) transporter
acsn021_14290	COG0789	Transcriptional regulator
acsn021_14300	COG4209	transmembrane transport
acsn021_14310	COG0395	ABC-type sugar transport system, permease component
acsn021_14320	COG1653	transport
acsn021_14330	COG1053	succinate dehydrogenase
acsn021_14370	COG3459	Glycosyltransferase 36 associated
acsn021_14380	COG4753	response regulator
acsn021_14380	COG2207	Transcriptional regulator
acsn021_14390	COG2972	Histidine kinase
acsn021_14450	COG0436	Aminotransferase
acsn021_14460	COG2502	aspartate--ammonia ligase
acsn021_14490	COG1937	Protein conserved in bacteria
acsn021_14510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_14520	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_14530	COG1120	ATPase activity
acsn021_14580	COG3620	sequence-specific DNA binding
acsn021_14610	COG2132	Multicopper oxidase
acsn021_14620	COG1737	Transcriptional regulator
acsn021_14630	COG2723	6-phospho-beta-galactosidase activity
acsn021_14650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
acsn021_14660	COG0583	DNA-binding transcription factor activity
acsn021_14670	COG0604	alcohol dehydrogenase
acsn021_14680	COG4412	M6 family metalloprotease domain protein
acsn021_14680	COG1404	Belongs to the peptidase S8 family
acsn021_14700	COG0375	protein maturation
acsn021_14760	COG0110	maltose O-acetyltransferase activity
acsn021_14770	COG3226	Transcriptional regulator
acsn021_14790	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
acsn021_14800	COG0745	RESPONSE REGULATOR receiver
acsn021_14810	COG5002	protein histidine kinase activity
acsn021_14810	COG3850	Histidine kinase
acsn021_14900	COG0561	phosphatase activity
acsn021_14910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
acsn021_14920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
acsn021_14930	COG1121	(ABC) transporter
acsn021_14940	COG0803	Belongs to the bacterial solute-binding protein 9 family
acsn021_14950	COG3401	FG-GAP repeat protein
acsn021_14960	COG0745	RESPONSE REGULATOR receiver
acsn021_14970	COG5002	protein histidine kinase activity
acsn021_15020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
acsn021_15040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
acsn021_15060	COG1447	Phosphotransferase system cellobiose-specific component IIA
acsn021_15070	COG2723	6-phospho-beta-galactosidase activity
acsn021_15090	COG4221	oxidoreductase activity
acsn021_15150	COG4753	response regulator
acsn021_15150	COG2207	Transcriptional regulator
acsn021_15160	COG2972	Histidine kinase
acsn021_15170	COG1879	ABC-type sugar transport system periplasmic component
acsn021_15190	COG1172	Belongs to the binding-protein-dependent transport system permease family
acsn021_15200	COG1172	Belongs to the binding-protein-dependent transport system permease family
acsn021_15210	COG0488	(ABC) transporter
acsn021_15230	COG1376	ErfK ybiS ycfS ynhG family protein
acsn021_15240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
acsn021_15260	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_15270	COG1917	Cupin 2, conserved barrel domain protein
acsn021_15270	COG2207	Transcriptional regulator
acsn021_15300	COG2207	Transcriptional regulator
acsn021_15310	COG4209	transmembrane transport
acsn021_15320	COG0395	ABC-type sugar transport system, permease component
acsn021_15360	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_15370	COG2972	Histidine kinase
acsn021_15380	COG2207	Transcriptional regulator
acsn021_15380	COG4753	response regulator
acsn021_15400	COG4209	transmembrane transport
acsn021_15410	COG0395	ABC-type sugar transport system, permease component
acsn021_15460	COG3279	Response regulator of the LytR AlgR family
acsn021_15500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
acsn021_15500	COG2070	2-Nitropropane dioxygenase
acsn021_15510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_15520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
acsn021_15530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_15530	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_15530	COG3321	synthase
acsn021_15530	COG4221	oxidoreductase activity
acsn021_15540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_15540	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_15540	COG3321	synthase
acsn021_15540	COG4221	oxidoreductase activity
acsn021_15550	COG3321	synthase
acsn021_15550	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_15550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_15550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
acsn021_15550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_15560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_15560	COG4221	oxidoreductase activity
acsn021_15560	COG0300	oxidoreductase activity
acsn021_15560	COG3321	synthase
acsn021_15570	COG4221	oxidoreductase activity
acsn021_15570	COG3321	synthase
acsn021_15570	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_15570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_15580	COG0300	oxidoreductase activity
acsn021_15580	COG3321	synthase
acsn021_15580	COG4221	oxidoreductase activity
acsn021_15580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_15590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_15590	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_15590	COG3321	synthase
acsn021_15590	COG4221	oxidoreductase activity
acsn021_15640	COG1024	Enoyl-CoA hydratase
acsn021_15650	COG3425	synthase
acsn021_15700	COG1136	(ABC) transporter
acsn021_15700	COG0577	efflux transmembrane transporter activity
acsn021_15710	COG1253	flavin adenine dinucleotide binding
acsn021_15750	COG0395	ABC-type sugar transport system, permease component
acsn021_15760	COG2972	Histidine kinase
acsn021_15800	COG1053	succinate dehydrogenase
acsn021_15800	COG0431	NADPH-dependent FMN reductase
acsn021_15800	COG3976	FMN-binding domain protein
acsn021_15830	COG1917	Cupin 2, conserved barrel domain protein
acsn021_15830	COG4977	sequence-specific DNA binding
acsn021_15850	COG1653	transport
acsn021_15870	COG0395	ABC-type sugar transport system, permease component
acsn021_15910	COG1175	transmembrane transport
acsn021_15920	COG0395	ABC-type sugar transport system, permease component
acsn021_15940	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_15980	COG1309	transcriptional regulator
acsn021_16000	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_16020	COG0765	amino acid transport
acsn021_16030	COG1126	abc transporter atp-binding protein
acsn021_16050	COG3250	beta-galactosidase activity
acsn021_16060	COG2723	6-phospho-beta-galactosidase activity
acsn021_16070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
acsn021_16080	COG1011	Hydrolase
acsn021_16090	COG1201	RNA secondary structure unwinding
acsn021_16200	COG3711	transcriptional antiterminator
acsn021_16220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_16220	COG2190	(PTS) system
acsn021_16220	COG1263	PTS System
acsn021_16230	COG1136	(ABC) transporter
acsn021_16230	COG0577	efflux transmembrane transporter activity
acsn021_16260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
acsn021_16280	COG1584	GPR1 FUN34 yaaH family protein
acsn021_16320	COG0789	Transcriptional regulator
acsn021_16340	COG0622	Phosphoesterase
acsn021_16360	COG0527	aspartate kinase activity
acsn021_16400	COG1874	Beta-galactosidase
acsn021_16450	COG0697	spore germination
acsn021_16460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
acsn021_16470	COG0428	transporter
acsn021_16490	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
acsn021_16490	COG0778	Nitroreductase
acsn021_16530	COG1132	(ABC) transporter
acsn021_16540	COG1120	ATPase activity
acsn021_16550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_16560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_16610	COG3620	sequence-specific DNA binding
acsn021_16620	COG1132	(ABC) transporter
acsn021_16640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
acsn021_16660	COG1971	Probably functions as a manganese efflux pump
acsn021_16730	COG2207	Transcriptional regulator
acsn021_16730	COG3708	Transcriptional regulator
acsn021_16770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
acsn021_16810	COG1674	ftsk spoiiie
acsn021_16820	COG2946	Replication initiation factor
acsn021_16890	COG0791	NLP P60 protein
acsn021_16890	COG0741	lytic transglycosylase activity
acsn021_16960	COG1131	(ABC) transporter
acsn021_17040	COG3344	reverse transcriptase
acsn021_17070	COG0840	transmembrane signaling receptor activity
acsn021_17120	COG1605	Chorismate mutase
acsn021_17120	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
acsn021_17170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_17210	COG0436	Aminotransferase
acsn021_17270	COG3959	Transketolase, thiamine diphosphate binding domain
acsn021_17280	COG3958	Transketolase
acsn021_17380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_17390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
acsn021_17430	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
acsn021_17480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_17500	COG0475	glutathione-regulated potassium exporter activity
acsn021_17520	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
acsn021_17530	COG4716	Myosin-crossreactive antigen
acsn021_17550	COG0275	rRNA processing
acsn021_17560	COG0513	Belongs to the DEAD box helicase family
acsn021_17600	COG2972	Histidine kinase
acsn021_17600	COG0745	RESPONSE REGULATOR receiver
acsn021_17610	COG3279	Response regulator of the LytR AlgR family
acsn021_17630	COG0544	peptidyl-prolyl cis-trans isomerase activity
acsn021_17640	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
acsn021_17670	COG2382	esterase
acsn021_17700	COG4209	transmembrane transport
acsn021_17710	COG0395	ABC-type sugar transport system, permease component
acsn021_17740	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_17750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
acsn021_17790	COG5646	InterPro IPR014922
acsn021_17810	COG1309	transcriptional regulator
acsn021_17830	COG4977	sequence-specific DNA binding
acsn021_17850	COG4209	transmembrane transport
acsn021_17860	COG0395	ABC-type sugar transport system, permease component
acsn021_17880	COG1408	metallophosphoesterase
acsn021_17890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_17900	COG2207	Transcriptional regulator
acsn021_17900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
acsn021_17960	COG3250	beta-galactosidase activity
acsn021_17980	COG1312	Catalyzes the dehydration of D-mannonate
acsn021_17990	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_18010	COG5002	protein histidine kinase activity
acsn021_18020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
acsn021_18070	COG0010	Belongs to the arginase family
acsn021_18150	COG4656	Part of a membrane complex involved in electron transport
acsn021_18240	COG0840	transmembrane signaling receptor activity
acsn021_18270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
acsn021_18280	COG1695	Transcriptional regulator
acsn021_18310	COG1268	BioY protein
acsn021_18320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
acsn021_18340	COG0572	uridine kinase
acsn021_18350	COG2214	Heat shock protein DnaJ domain protein
acsn021_18360	COG0443	Heat shock 70 kDa protein
acsn021_18390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
acsn021_18400	COG0420	3'-5' exonuclease activity
acsn021_18410	COG0419	ATPase involved in DNA repair
acsn021_18420	COG0714	Associated with various cellular activities
acsn021_18440	COG3552	Protein containing von Willebrand factor type A (VWA) domain
acsn021_18470	COG3831	ATPase activity
acsn021_18480	COG0747	negative chemotaxis
acsn021_18490	COG0601	transmembrane transport
acsn021_18500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_18510	COG0444	Belongs to the ABC transporter superfamily
acsn021_18520	COG4608	Belongs to the ABC transporter superfamily
acsn021_18590	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
acsn021_18600	COG0673	inositol 2-dehydrogenase activity
acsn021_18620	COG4977	sequence-specific DNA binding
acsn021_18650	COG0277	FAD linked oxidase domain protein
acsn021_18660	COG3711	transcriptional antiterminator
acsn021_18670	COG1263	PTS System
acsn021_18670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_18670	COG2190	(PTS) system
acsn021_18720	COG5566	PFAM Mor transcription activator
acsn021_18780	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
acsn021_18820	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
acsn021_18850	COG0583	DNA-binding transcription factor activity
acsn021_18860	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
acsn021_18870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
acsn021_18880	COG0459	protein refolding
acsn021_18890	COG0250	Participates in transcription elongation, termination and antitermination
acsn021_18970	COG2207	Transcriptional regulator
acsn021_18980	COG0457	Tetratricopeptide repeat
acsn021_19000	COG0561	phosphatase activity
acsn021_19010	COG3711	transcriptional antiterminator
acsn021_19020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_19020	COG2190	(PTS) system
acsn021_19020	COG1263	PTS System
acsn021_19030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
acsn021_19060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
acsn021_19110	COG0519	Catalyzes the synthesis of GMP from XMP
acsn021_19120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
acsn021_19190	COG1518	maintenance of DNA repeat elements
acsn021_19200	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
acsn021_19210	COG1486	melibiose metabolic process
acsn021_19260	COG3250	beta-galactosidase activity
acsn021_19270	COG1917	Cupin 2, conserved barrel domain protein
acsn021_19270	COG2207	Transcriptional regulator
acsn021_19280	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_19300	COG4209	transmembrane transport
acsn021_19310	COG0395	ABC-type sugar transport system, permease component
acsn021_19330	COG1151	hydroxylamine reductase activity
acsn021_19340	COG1696	Membrane protein involved in D-alanine export
acsn021_19360	COG3279	Response regulator of the LytR AlgR family
acsn021_19410	COG1917	Cupin 2, conserved barrel domain protein
acsn021_19410	COG2207	Transcriptional regulator
acsn021_19420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
acsn021_19450	COG1349	DNA-binding transcription factor activity
acsn021_19460	COG1105	Belongs to the carbohydrate kinase PfkB family
acsn021_19470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
acsn021_19470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
acsn021_19470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
acsn021_19700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
acsn021_19710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
acsn021_19730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_19740	COG1250	3-hydroxyacyl-CoA dehydrogenase
acsn021_19740	COG1024	Enoyl-CoA hydratase
acsn021_19750	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
acsn021_19770	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
acsn021_19780	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_19810	COG0318	PFAM AMP-dependent synthetase and ligase
acsn021_19810	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_19810	COG3321	synthase
acsn021_19810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_19810	COG0300	oxidoreductase activity
acsn021_19820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_19820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
acsn021_19820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_19820	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_19820	COG3321	synthase
acsn021_19830	COG4221	oxidoreductase activity
acsn021_19830	COG3321	synthase
acsn021_19830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_19830	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_19840	COG4221	oxidoreductase activity
acsn021_19840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_19840	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_19840	COG3321	synthase
acsn021_19850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_19850	COG0300	oxidoreductase activity
acsn021_19850	COG3321	synthase
acsn021_19850	COG4221	oxidoreductase activity
acsn021_19850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_19850	COG0300	oxidoreductase activity
acsn021_19850	COG3321	synthase
acsn021_19850	COG4221	oxidoreductase activity
acsn021_19860	COG4221	oxidoreductase activity
acsn021_19860	COG3321	synthase
acsn021_19860	COG0300	oxidoreductase activity
acsn021_19860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_19880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_19880	COG3321	synthase
acsn021_19880	COG4221	oxidoreductase activity
acsn021_19880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_19880	COG0300	oxidoreductase activity
acsn021_19880	COG3321	synthase
acsn021_19880	COG0300	oxidoreductase activity
acsn021_19880	COG4221	oxidoreductase activity
acsn021_19920	COG1131	(ABC) transporter
acsn021_20030	COG3620	sequence-specific DNA binding
acsn021_20110	COG1335	isochorismatase
acsn021_20130	COG2226	methyltransferase
acsn021_20140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
acsn021_20310	COG1690	Belongs to the RtcB family
acsn021_20340	COG5634	Uncharacterized conserved protein (DUF2278)
acsn021_20380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
acsn021_20430	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
acsn021_20430	COG2508	Transcriptional regulator
acsn021_20440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
acsn021_20560	COG1393	Belongs to the ArsC family
acsn021_20570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
acsn021_20630	COG0521	Mo-molybdopterin cofactor biosynthetic process
acsn021_20640	COG1606	tRNA processing
acsn021_20780	COG2223	nitrite transmembrane transporter activity
acsn021_20820	COG4221	oxidoreductase activity
acsn021_20860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
acsn021_20880	COG0386	Belongs to the glutathione peroxidase family
acsn021_20890	COG3118	belongs to the thioredoxin family
acsn021_20900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
acsn021_20910	COG1321	iron dependent repressor
acsn021_20920	COG1879	ABC-type sugar transport system periplasmic component
acsn021_20940	COG0765	amino acid transport
acsn021_20950	COG1126	abc transporter atp-binding protein
acsn021_20970	COG3858	chitin binding
acsn021_20970	COG1388	LysM domain
acsn021_20980	COG1846	Transcriptional regulator
acsn021_20990	COG0386	Belongs to the glutathione peroxidase family
acsn021_21000	COG0004	ammonium transporteR
acsn021_21010	COG1725	Transcriptional regulator
acsn021_21020	COG1131	(ABC) transporter
acsn021_21080	COG0395	ABC-type sugar transport system, permease component
acsn021_21120	COG1175	transmembrane transport
acsn021_21130	COG0395	ABC-type sugar transport system, permease component
acsn021_21150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
acsn021_21160	COG1104	cysteine desulfurase activity
acsn021_21170	COG0037	tRNA processing
acsn021_21180	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
acsn021_21200	COG0287	Prephenate dehydrogenase
acsn021_21210	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
acsn021_21220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
acsn021_21230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
acsn021_21280	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
acsn021_21300	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
acsn021_21310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
acsn021_21320	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
acsn021_21330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
acsn021_21350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
acsn021_21360	COG2135	peptidase activity
acsn021_21400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_21420	COG2195	Cleaves the N-terminal amino acid of tripeptides
acsn021_21430	COG0129	dihydroxy-acid dehydratase activity
acsn021_21450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
acsn021_21460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
acsn021_21480	COG1785	Belongs to the alkaline phosphatase family
acsn021_21500	COG1687	branched-chain amino acid
acsn021_21510	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
acsn021_21530	COG1482	cell wall glycoprotein biosynthetic process
acsn021_21550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
acsn021_21560	COG0668	transmembrane transport
acsn021_21600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
acsn021_21610	COG0235	Class ii aldolase
acsn021_21630	COG1307	EDD domain protein, DegV family
acsn021_21650	COG1070	Carbohydrate kinase
acsn021_21660	COG4806	L-rhamnose isomerase
acsn021_21680	COG0235	Class ii aldolase
acsn021_21710	COG1063	alcohol dehydrogenase
acsn021_21760	COG4869	propanediol catabolic process
acsn021_21770	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
acsn021_21800	COG1349	DNA-binding transcription factor activity
acsn021_21810	COG1882	Formate acetyltransferase
acsn021_21820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
acsn021_21910	COG3976	FMN-binding domain protein
acsn021_21910	COG1053	succinate dehydrogenase
acsn021_21930	COG0840	transmembrane signaling receptor activity
acsn021_21960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
acsn021_21960	COG0512	Glutamine amidotransferase of anthranilate synthase
acsn021_21970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
acsn021_21980	COG0134	indole-3-glycerol-phosphate synthase activity
acsn021_21990	COG0135	phosphoribosylanthranilate isomerase activity
acsn021_22000	COG0133	tryptophan synthase activity
acsn021_22030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
acsn021_22050	COG1132	(ABC) transporter
acsn021_22100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
acsn021_22110	COG2207	Transcriptional regulator
acsn021_22150	COG0840	transmembrane signaling receptor activity
acsn021_22160	COG3384	dioxygenase
acsn021_22170	COG1741	Belongs to the pirin family
acsn021_22180	COG0745	RESPONSE REGULATOR receiver
acsn021_22190	COG5002	protein histidine kinase activity
acsn021_22250	COG0778	Nitroreductase
acsn021_22280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
acsn021_22300	COG1733	regulation of RNA biosynthetic process
acsn021_22310	COG1733	regulation of RNA biosynthetic process
acsn021_22380	COG2135	peptidase activity
acsn021_22430	COG1086	Polysaccharide biosynthesis protein
acsn021_22440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
acsn021_22450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
acsn021_22490	COG1216	Glycosyl transferase, family 2
acsn021_22490	COG1442	glycosyl transferase family 8
acsn021_22520	COG1086	Polysaccharide biosynthesis protein
acsn021_22600	COG1215	transferase activity, transferring glycosyl groups
acsn021_22630	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_22730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
acsn021_22770	COG0798	PFAM Bile acid sodium symporter
acsn021_22780	COG0640	Transcriptional regulator
acsn021_22790	COG0446	pyridine nucleotide-disulphide oxidoreductase
acsn021_22800	COG0640	Transcriptional regulator
acsn021_22820	COG1846	Transcriptional regulator
acsn021_22830	COG1247	-acetyltransferase
acsn021_22840	COG1649	PFAM Uncharacterised BCR, COG1649
acsn021_22850	COG2247	cell wall binding repeat
acsn021_22850	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_22870	COG4974	Belongs to the 'phage' integrase family
acsn021_22890	COG1132	(ABC) transporter
acsn021_22920	COG1309	transcriptional regulator
acsn021_22940	COG1131	(ABC) transporter
acsn021_22960	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
acsn021_22960	COG1918	ferrous iron import across plasma membrane
acsn021_22970	COG1918	ferrous iron import across plasma membrane
acsn021_22970	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
acsn021_23060	COG1760	l-serine dehydratase
acsn021_23070	COG1760	l-serine dehydratase
acsn021_23080	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
acsn021_23090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
acsn021_23100	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
acsn021_23120	COG3534	alpha-L-arabinofuranosidase
acsn021_23140	COG0028	Belongs to the TPP enzyme family
acsn021_23150	COG0440	acetolactate synthase activity
acsn021_23180	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_23180	COG2247	cell wall binding repeat
acsn021_23200	COG0469	pyruvate kinase activity
acsn021_23230	COG0617	tRNA 3'-terminal CCA addition
acsn021_23240	COG0437	4 iron, 4 sulfur cluster binding
acsn021_23260	COG0822	iron-sulfur transferase activity
acsn021_23270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
acsn021_23280	COG0719	Fe-S assembly protein
acsn021_23290	COG0719	Fe-S assembly protein
acsn021_23360	COG1737	Transcriptional regulator
acsn021_23370	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
acsn021_23380	COG0363	glucosamine-6-phosphate deaminase activity
acsn021_23390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
acsn021_23410	COG1394	ATPase activity, coupled to movement of substances
acsn021_23420	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
acsn021_23430	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
acsn021_23460	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
acsn021_23470	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
acsn021_23480	COG1269	ATP hydrolysis coupled proton transport
acsn021_23540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
acsn021_23560	COG0535	radical SAM domain protein
acsn021_23560	COG1433	Dinitrogenase iron-molybdenum cofactor
acsn021_23600	COG0347	Belongs to the P(II) protein family
acsn021_23610	COG0347	Belongs to the P(II) protein family
acsn021_23620	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
acsn021_23650	COG0745	RESPONSE REGULATOR receiver
acsn021_23710	COG0602	queuosine metabolic process
acsn021_23790	COG0697	spore germination
acsn021_23800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
acsn021_23810	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
acsn021_23830	COG1408	metallophosphoesterase
acsn021_23840	COG1686	Belongs to the peptidase S11 family
acsn021_23910	COG1758	RNA polymerase activity
acsn021_23920	COG2052	Domain of unknown function (DUF370)
acsn021_23930	COG1561	YicC-like family, N-terminal region
acsn021_23950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
acsn021_23960	COG0482	sulfurtransferase activity
acsn021_23970	COG0822	iron-sulfur transferase activity
acsn021_24010	COG5001	Diguanylate cyclase
acsn021_24020	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
acsn021_24060	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
acsn021_24080	COG1032	radical SAM domain protein
acsn021_24100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
acsn021_24120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
acsn021_24230	COG0318	PFAM AMP-dependent synthetase and ligase
acsn021_24260	COG4555	ABC transporter
acsn021_24270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
acsn021_24310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
acsn021_24310	COG2207	Transcriptional regulator
acsn021_24320	COG2376	Dihydroxyacetone kinase
acsn021_24360	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_24380	COG0395	ABC-type sugar transport system, permease component
acsn021_24400	COG1501	Belongs to the glycosyl hydrolase 31 family
acsn021_24430	COG0583	DNA-binding transcription factor activity
acsn021_24450	COG3833	ABC-type maltose transport systems, permease component
acsn021_24460	COG1175	transmembrane transport
acsn021_24470	COG2182	Extracellular solute-binding protein
acsn021_24530	COG2746	aminoglycoside 3-N-acetyltransferase activity
acsn021_24540	COG1136	(ABC) transporter
acsn021_24550	COG0745	RESPONSE REGULATOR receiver
acsn021_24560	COG1136	(ABC) transporter
acsn021_24570	COG0577	efflux transmembrane transporter activity
acsn021_24580	COG2205	protein histidine kinase activity
acsn021_24590	COG0745	RESPONSE REGULATOR receiver
acsn021_24600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
acsn021_24650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
acsn021_24660	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
acsn021_24670	COG1187	pseudouridine synthase activity
acsn021_24690	COG2323	membrane
acsn021_24760	COG5002	protein histidine kinase activity
acsn021_24770	COG2954	triphosphatase activity
acsn021_24800	COG2267	carboxylic ester hydrolase activity
acsn021_24810	COG0488	(ABC) transporter
acsn021_24820	COG2246	polysaccharide biosynthetic process
acsn021_24850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_24860	COG0601	transmembrane transport
acsn021_24870	COG4608	Belongs to the ABC transporter superfamily
acsn021_24880	COG0444	Belongs to the ABC transporter superfamily
acsn021_24950	COG1595	DNA-templated transcription, initiation
acsn021_25000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
acsn021_25010	COG1982	Orn Lys Arg decarboxylase major
acsn021_25020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
acsn021_25030	COG0826	peptidase U32
acsn021_25040	COG4122	O-methyltransferase activity
acsn021_25060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
acsn021_25070	COG0735	belongs to the Fur family
acsn021_25090	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
acsn021_25100	COG4472	Bacterial protein of unknown function (DUF965)
acsn021_25110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_25130	COG0301	tRNA thio-modification
acsn021_25140	COG1104	cysteine desulfurase activity
acsn021_25150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
acsn021_25160	COG2264	protein methyltransferase activity
acsn021_25170	COG0484	heat shock protein binding
acsn021_25180	COG0443	Heat shock 70 kDa protein
acsn021_25190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
acsn021_25200	COG1420	regulation of RNA biosynthetic process
acsn021_25210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
acsn021_25220	COG0481	GTPase activity
acsn021_25240	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
acsn021_25250	COG0268	Binds directly to 16S ribosomal RNA
acsn021_25260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
acsn021_25270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
acsn021_25300	COG0799	negative regulation of ribosome biogenesis
acsn021_25310	COG1713	HD superfamily hydrolase involved in NAD metabolism
acsn021_25320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
acsn021_25330	COG1534	Rna-binding protein
acsn021_25340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
acsn021_25350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
acsn021_25360	COG2868	ribosomal protein
acsn021_25370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
acsn021_25390	COG3192	ethanolamine utilization protein
acsn021_25420	COG4820	ethanolamine utilization protein (EutJ)
acsn021_25430	COG4869	propanediol catabolic process
acsn021_25460	COG1012	belongs to the aldehyde dehydrogenase family
acsn021_25460	COG1454	alcohol dehydrogenase
acsn021_25500	COG4303	Ethanolamine ammonia lyase large subunit
acsn021_25560	COG0840	transmembrane signaling receptor activity
acsn021_25600	COG2304	oxidoreductase activity
acsn021_25630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
acsn021_25640	COG1530	ribonuclease E activity
acsn021_25680	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
acsn021_25690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
acsn021_25710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
acsn021_25730	COG2116	formate transmembrane transporter activity
acsn021_25780	COG1686	Belongs to the peptidase S11 family
acsn021_25790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
acsn021_25800	COG0252	asparaginase activity
acsn021_25810	COG1181	Belongs to the D-alanine--D-alanine ligase family
acsn021_25840	COG1924	4 iron, 4 sulfur cluster binding
acsn021_25890	COG0564	pseudouridine synthase activity
acsn021_25900	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
acsn021_25910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
acsn021_25920	COG3599	regulation of cell shape
acsn021_25950	COG1799	cell septum assembly
acsn021_25960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
acsn021_25980	COG2155	Conserved Protein
acsn021_26000	COG1686	Belongs to the peptidase S11 family
acsn021_26010	COG1803	Methylglyoxal synthase
acsn021_26030	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
acsn021_26040	COG2894	cell division
acsn021_26060	COG0768	penicillin binding
acsn021_26100	COG2003	Belongs to the UPF0758 family
acsn021_26120	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
acsn021_26130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
acsn021_26150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
acsn021_26160	COG0328	RNA-DNA hybrid ribonuclease activity
acsn021_26230	COG0395	ABC-type sugar transport system, permease component
acsn021_26240	COG4209	transmembrane transport
acsn021_26320	COG3064	Membrane
acsn021_26320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
acsn021_26320	COG3583	domain protein
acsn021_26330	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_26350	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
acsn021_26370	COG1408	metallophosphoesterase
acsn021_26390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
acsn021_26400	COG3344	reverse transcriptase
acsn021_26420	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
acsn021_26440	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
acsn021_26450	COG1160	GTP binding
acsn021_26480	COG2226	methyltransferase
acsn021_26490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
acsn021_26500	COG1496	oxidoreductase activity
acsn021_26510	COG0792	nuclease activity
acsn021_26520	COG2257	FlhB HrpN YscU SpaS Family
acsn021_26530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
acsn021_26540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
acsn021_26560	COG0335	large ribosomal subunit rRNA binding
acsn021_26580	COG0336	Belongs to the RNA methyltransferase TrmD family
acsn021_26590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
acsn021_26610	COG0228	four-way junction DNA binding
acsn021_26620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
acsn021_26660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
acsn021_26680	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
acsn021_26690	COG0511	ligase activity, forming carbon-carbon bonds
acsn021_26710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
acsn021_26720	COG2137	regulation of response to DNA damage stimulus
acsn021_26730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
acsn021_26740	COG1247	-acetyltransferase
acsn021_26750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
acsn021_26760	COG0552	protein localization to endoplasmic reticulum
acsn021_26770	COG1196	nuclear chromosome segregation
acsn021_26780	COG0571	ribonuclease III activity
acsn021_26790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_26800	COG0416	fatty acid biosynthetic process
acsn021_26810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
acsn021_26820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
acsn021_26820	COG0539	negative regulation of cytoplasmic translation
acsn021_26840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
acsn021_26850	COG2081	HI0933 family
acsn021_26870	COG1546	Belongs to the CinA family
acsn021_26870	COG1058	Belongs to the CinA family
acsn021_26880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
acsn021_26890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_26920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
acsn021_26930	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
acsn021_26940	COG1609	Transcriptional regulator
acsn021_26960	COG0395	ABC-type sugar transport system, permease component
acsn021_26970	COG1175	transmembrane transport
acsn021_27010	COG2721	sulfolactate sulfo-lyase activity
acsn021_27020	COG0246	Mannitol dehydrogenase
acsn021_27030	COG1609	Transcriptional regulator
acsn021_27040	COG1904	glucuronate isomerase
acsn021_27060	COG0540	Belongs to the ATCase OTCase family
acsn021_27070	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
acsn021_27080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
acsn021_27090	COG2759	Belongs to the formate--tetrahydrofolate ligase family
acsn021_27110	COG0546	phosphoglycolate phosphatase activity
acsn021_27120	COG0017	Asparaginyl-tRNA synthetase
acsn021_27190	COG0740	serine-type endopeptidase activity
acsn021_27200	COG0371	Dehydrogenase
acsn021_27210	COG0612	Peptidase, M16
acsn021_27240	COG2226	methyltransferase
acsn021_27260	COG4149	molybdate abc transporter
acsn021_27270	COG0725	ABC transporter, periplasmic molybdate-binding protein
acsn021_27280	COG1185	polyribonucleotide nucleotidyltransferase activity
acsn021_27290	COG0445	tRNA wobble uridine modification
acsn021_27300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
acsn021_27310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
acsn021_27320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
acsn021_27330	COG0395	ABC-type sugar transport system, permease component
acsn021_27340	COG1175	transmembrane transport
acsn021_27360	COG2972	Histidine kinase
acsn021_27370	COG2207	Transcriptional regulator
acsn021_27370	COG4753	response regulator
acsn021_27380	COG2217	Heavy metal translocating P-type atpase
acsn021_27410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
acsn021_27440	COG0504	CTP synthase activity
acsn021_27460	COG0789	Transcriptional regulator
acsn021_27480	COG1131	(ABC) transporter
acsn021_27490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
acsn021_27500	COG0196	riboflavin kinase activity
acsn021_27510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
acsn021_27520	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
acsn021_27530	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
acsn021_27540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
acsn021_27570	COG0195	Participates in both transcription termination and antitermination
acsn021_27580	COG0779	Required for maturation of 30S ribosomal subunits
acsn021_27600	COG0131	Imidazoleglycerol-phosphate dehydratase
acsn021_27610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
acsn021_27620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
acsn021_27630	COG0124	histidyl-tRNA synthetase
acsn021_27650	COG3331	DNA recombination
acsn021_27680	COG1187	pseudouridine synthase activity
acsn021_27690	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
acsn021_27690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
acsn021_27700	COG2357	RelA SpoT domain protein
acsn021_27720	COG1316	TRANSCRIPTIONal
acsn021_27730	COG2843	Capsule synthesis protein
acsn021_27740	COG2195	Cleaves the N-terminal amino acid of tripeptides
acsn021_27750	COG2848	UPF0210 protein
acsn021_27770	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
acsn021_27780	COG0849	cell division
acsn021_27790	COG0237	dephospho-CoA kinase activity
acsn021_27800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
acsn021_27800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
acsn021_27820	COG3409	Peptidoglycan-binding domain 1 protein
acsn021_27820	COG0793	Belongs to the peptidase S41A family
acsn021_27870	COG1191	sigma factor activity
acsn021_27890	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
acsn021_27900	COG1776	CheC inhibitor of MCP methylation
acsn021_27920	COG2198	Histidine kinase
acsn021_27920	COG0643	Histidine kinase
acsn021_27930	COG2201	protein-glutamate methylesterase activity
acsn021_27960	COG1419	protein localization to endoplasmic reticulum
acsn021_27970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
acsn021_27980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
acsn021_27990	COG1684	flagellar biosynthetic protein fliR
acsn021_28000	COG1987	bacterial-type flagellum assembly
acsn021_28010	COG1338	Plays a role in the flagellum-specific transport system
acsn021_28030	COG2201	protein-glutamate methylesterase activity
acsn021_28040	COG1776	CheC inhibitor of MCP methylation
acsn021_28040	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
acsn021_28050	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
acsn021_28070	COG1360	Flagellar Motor Protein
acsn021_28090	COG1582	Flagellar protein (FlbD)
acsn021_28120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
acsn021_28160	COG1157	protein secretion by the type III secretion system
acsn021_28180	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
acsn021_28200	COG1677	Flagellar hook-basal body complex protein FliE
acsn021_28210	COG1558	bacterial-type flagellum-dependent cell motility
acsn021_28220	COG1815	bacterial-type flagellum-dependent cell motility
acsn021_28240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
acsn021_28250	COG0758	DNA mediated transformation
acsn021_28260	COG0606	chelatase, subunit chli
acsn021_28270	COG0519	Catalyzes the synthesis of GMP from XMP
acsn021_28280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
acsn021_28310	COG1191	sigma factor activity
acsn021_28320	COG1191	sigma factor activity
acsn021_28340	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
acsn021_28360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
acsn021_28370	COG0772	Belongs to the SEDS family
acsn021_28380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
acsn021_28400	COG0768	penicillin binding
acsn021_28410	COG0768	penicillin binding
acsn021_28430	COG0275	rRNA processing
acsn021_28440	COG2001	Belongs to the MraZ family
acsn021_28450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
acsn021_28460	COG0012	GTP binding
acsn021_28480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
acsn021_28500	COG2815	serine threonine protein kinase
acsn021_28500	COG0515	serine threonine protein kinase
acsn021_28510	COG0631	protein serine/threonine phosphatase activity
acsn021_28520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
acsn021_28530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
acsn021_28530	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
acsn021_28540	COG2738	Putative neutral zinc metallopeptidase
acsn021_28560	COG0242	peptide deformylase activity
acsn021_28570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
acsn021_28580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
acsn021_28590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
acsn021_28640	COG0395	ABC-type sugar transport system, permease component
acsn021_28680	COG0395	ABC-type sugar transport system, permease component
acsn021_28690	COG1175	transmembrane transport
acsn021_28720	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_28730	COG3940	Belongs to the glycosyl hydrolase 43 family
acsn021_28770	COG1136	(ABC) transporter
acsn021_28780	COG0642	Histidine kinase
acsn021_28790	COG0745	RESPONSE REGULATOR receiver
acsn021_28800	COG1725	Transcriptional regulator
acsn021_28810	COG1131	(ABC) transporter
acsn021_28860	COG0242	peptide deformylase activity
acsn021_28870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
acsn021_28880	COG4974	Belongs to the 'phage' integrase family
acsn021_28910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
acsn021_28930	COG1418	mRNA catabolic process
acsn021_28940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_28970	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
acsn021_28980	COG1518	maintenance of DNA repeat elements
acsn021_29090	COG1404	Belongs to the peptidase S8 family
acsn021_29110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
acsn021_29120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
acsn021_29130	COG4224	UPF0291 protein
acsn021_29140	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
acsn021_29150	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
acsn021_29160	COG2081	HI0933 family
acsn021_29180	COG4176	ABC-type proline glycine betaine transport system permease component
acsn021_29210	COG1136	(ABC) transporter
acsn021_29310	COG0232	Belongs to the dGTPase family. Type 2 subfamily
acsn021_29320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
acsn021_29330	COG0113	porphobilinogen synthase activity
acsn021_29350	COG0181	hydroxymethylbilane synthase activity
acsn021_29360	COG1648	precorrin-2 dehydrogenase activity
acsn021_29360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
acsn021_29370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
acsn021_29390	COG0495	leucyl-tRNA aminoacylation
acsn021_29410	COG0569	domain protein
acsn021_29420	COG4154	Belongs to the RbsD FucU family
acsn021_29430	COG1070	Carbohydrate kinase
acsn021_29440	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
acsn021_29480	COG2895	sulfate adenylyltransferase (ATP) activity
acsn021_29490	COG0175	sulfate reduction
acsn021_29500	COG1245	4Fe-4S binding domain
acsn021_29500	COG2878	Part of a membrane complex involved in electron transport
acsn021_29520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
acsn021_29530	COG4208	sulfate ABC transporter
acsn021_29550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
acsn021_29580	COG2244	polysaccharide biosynthetic process
acsn021_29600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
acsn021_29620	COG1702	phosphate starvation-inducible protein PhoH
acsn021_29680	COG1175	transmembrane transport
acsn021_29700	COG5002	protein histidine kinase activity
acsn021_29710	COG0745	RESPONSE REGULATOR receiver
acsn021_29720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
acsn021_29750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
acsn021_29880	COG1983	PspC domain protein
acsn021_29930	COG2205	protein histidine kinase activity
acsn021_29940	COG0745	RESPONSE REGULATOR receiver
acsn021_29960	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
acsn021_29970	COG0750	zinc metalloprotease
acsn021_29980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
acsn021_29990	COG4589	Belongs to the CDS family
acsn021_30000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
acsn021_30010	COG0233	cytoplasmic translational termination
acsn021_30060	COG0673	inositol 2-dehydrogenase activity
acsn021_30070	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
acsn021_30080	COG0052	Belongs to the universal ribosomal protein uS2 family
acsn021_30090	COG1051	belongs to the nudix hydrolase family
acsn021_30110	COG0772	Belongs to the SEDS family
acsn021_30120	COG0826	peptidase U32
acsn021_30150	COG2255	four-way junction helicase activity
acsn021_30160	COG0632	four-way junction helicase activity
acsn021_30170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
acsn021_30200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
acsn021_30220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
acsn021_30230	COG0280	phosphate acetyltransferase
acsn021_30240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
acsn021_30290	COG3279	Response regulator of the LytR AlgR family
acsn021_30300	COG1323	Belongs to the UPF0348 family
acsn021_30310	COG1164	Oligoendopeptidase f
acsn021_30350	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
acsn021_30360	COG0742	ribosomal rna small subunit methyltransferase
acsn021_30390	COG0463	Glycosyl transferase, family 2
acsn021_30420	COG0463	Glycosyl transferase, family 2
acsn021_30430	COG0464	growth
acsn021_30440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
acsn021_30450	COG1461	Dihydroxyacetone kinase
acsn021_30460	COG1302	Protein conserved in bacteria
acsn021_30470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
acsn021_30550	COG0673	inositol 2-dehydrogenase activity
acsn021_30570	COG0673	inositol 2-dehydrogenase activity
acsn021_30580	COG0561	phosphatase activity
acsn021_30670	COG0488	(ABC) transporter
acsn021_30730	COG3620	sequence-specific DNA binding
acsn021_30750	COG5444	nuclease activity
acsn021_30790	COG3620	sequence-specific DNA binding
acsn021_30870	COG3620	sequence-specific DNA binding
acsn021_30950	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
acsn021_30950	COG2755	lipolytic protein G-D-S-L family
acsn021_30960	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_30960	COG1388	LysM domain
acsn021_31000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
acsn021_31030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
acsn021_31040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
acsn021_31050	COG0583	DNA-binding transcription factor activity
acsn021_31070	COG0107	imidazoleglycerol-phosphate synthase activity
acsn021_31080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
acsn021_31100	COG0835	chemotaxis
acsn021_31100	COG0784	Response regulator, receiver
acsn021_31110	COG2205	protein histidine kinase activity
acsn021_31120	COG2337	Toxic component of a toxin-antitoxin (TA) module
acsn021_31130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
acsn021_31140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
acsn021_31140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
acsn021_31160	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
acsn021_31170	COG0488	(ABC) transporter
acsn021_31180	COG1802	Transcriptional regulator
acsn021_31190	COG0473	3-isopropylmalate dehydrogenase activity
acsn021_31200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
acsn021_31210	COG0549	Belongs to the carbamate kinase family
acsn021_31230	COG0367	asparagine synthase
acsn021_31240	COG3290	protein histidine kinase activity
acsn021_31240	COG0840	transmembrane signaling receptor activity
acsn021_31260	COG1464	Belongs to the NlpA lipoprotein family
acsn021_31270	COG2011	ABC-type metal ion transport system permease component
acsn021_31280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
acsn021_31290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
acsn021_31290	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
acsn021_31290	COG1013	pyruvate-flavodoxin oxidoreductase activity
acsn021_31290	COG0674	pyruvate-flavodoxin oxidoreductase activity
acsn021_31310	COG5001	Diguanylate cyclase
acsn021_31310	COG3300	MHYT domain
acsn021_31320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
acsn021_31340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
acsn021_31350	COG1802	Transcriptional regulator
acsn021_31360	COG0246	Mannitol dehydrogenase
acsn021_31370	COG1312	Catalyzes the dehydration of D-mannonate
acsn021_31450	COG0840	transmembrane signaling receptor activity
acsn021_31480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
acsn021_31490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
acsn021_31500	COG1404	Belongs to the peptidase S8 family
acsn021_31510	COG1592	Rubrerythrin
acsn021_31520	COG1013	pyruvate-flavodoxin oxidoreductase activity
acsn021_31530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
acsn021_31530	COG0674	pyruvate-flavodoxin oxidoreductase activity
acsn021_31580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
acsn021_31590	COG1396	sequence-specific DNA binding
acsn021_31600	COG3842	ATPase activity
acsn021_31610	COG1176	ABC-type spermidine putrescine transport system, permease component I
acsn021_31620	COG1177	transmembrane transport
acsn021_31630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
acsn021_31640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
acsn021_31670	COG1854	S-ribosylhomocysteine lyase activity
acsn021_31710	COG2201	protein-glutamate methylesterase activity
acsn021_31730	COG0840	transmembrane signaling receptor activity
acsn021_31740	COG0835	chemotaxis
acsn021_31750	COG2198	Histidine kinase
acsn021_31750	COG0643	Histidine kinase
acsn021_31760	COG2201	protein-glutamate methylesterase activity
acsn021_31770	COG1376	ErfK ybiS ycfS ynhG family protein
acsn021_31780	COG1132	(ABC) transporter
acsn021_31800	COG0534	Mate efflux family protein
acsn021_31830	COG4166	transmembrane transport
acsn021_31840	COG4608	Belongs to the ABC transporter superfamily
acsn021_31850	COG0444	Belongs to the ABC transporter superfamily
acsn021_31860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_31870	COG0601	transmembrane transport
acsn021_31890	COG0148	phosphopyruvate hydratase activity
acsn021_31900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
acsn021_31910	COG0165	Argininosuccinate lyase
acsn021_31920	COG5658	integral membrane protein
acsn021_31930	COG0640	Transcriptional regulator
acsn021_31950	COG1131	(ABC) transporter
acsn021_31980	COG1937	Protein conserved in bacteria
acsn021_31990	COG2217	Heavy metal translocating P-type atpase
acsn021_32010	COG0129	dihydroxy-acid dehydratase activity
acsn021_32060	COG1595	DNA-templated transcription, initiation
acsn021_32090	COG5002	protein histidine kinase activity
acsn021_32110	COG1555	photosystem II stabilization
acsn021_32110	COG1596	polysaccharide export
acsn021_32130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
acsn021_32140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
acsn021_32150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
acsn021_32160	COG0424	maF-like protein
acsn021_32170	COG0137	argininosuccinate synthase activity
acsn021_32210	COG0561	phosphatase activity
acsn021_32220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
acsn021_32240	COG1126	abc transporter atp-binding protein
acsn021_32250	COG0765	amino acid transport
acsn021_32270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
acsn021_32290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
acsn021_32320	COG2966	Psort location CytoplasmicMembrane, score
acsn021_32350	COG5002	protein histidine kinase activity
acsn021_32360	COG0745	RESPONSE REGULATOR receiver
acsn021_32370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
acsn021_32410	COG1388	LysM domain
acsn021_32410	COG3942	CHAP domain
acsn021_32470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
acsn021_32480	COG0557	exoribonuclease II activity
acsn021_32490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
acsn021_32500	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
acsn021_32510	COG0149	triose-phosphate isomerase activity
acsn021_32560	COG0297	glycogen (starch) synthase activity
acsn021_32570	COG0745	RESPONSE REGULATOR receiver
acsn021_32580	COG0750	zinc metalloprotease
acsn021_32590	COG0497	DNA recombination
acsn021_32600	COG2198	Histidine kinase
acsn021_32600	COG0643	Histidine kinase
acsn021_32610	COG2201	protein-glutamate methylesterase activity
acsn021_32730	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
acsn021_32740	COG0217	transcriptional regulatory protein
acsn021_32750	COG1438	arginine binding
acsn021_32760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
acsn021_32770	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
acsn021_32780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
acsn021_32800	COG1722	exodeoxyribonuclease VII activity
acsn021_32810	COG1570	exodeoxyribonuclease VII activity
acsn021_32820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
acsn021_32830	COG1302	Protein conserved in bacteria
acsn021_32910	COG3854	ATPases associated with a variety of cellular activities
acsn021_32920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
acsn021_32940	COG0066	3-isopropylmalate dehydratase activity
acsn021_32950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
acsn021_32960	COG0473	3-isopropylmalate dehydrogenase activity
acsn021_32970	COG0583	DNA-binding transcription factor activity
acsn021_32990	COG1194	a g-specific adenine glycosylase
acsn021_33000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
acsn021_33010	COG0440	acetolactate synthase activity
acsn021_33040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
acsn021_33050	COG0077	Prephenate dehydratase
acsn021_33050	COG1605	Chorismate mutase
acsn021_33060	COG0285	dihydrofolate synthase activity
acsn021_33070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
acsn021_33090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
acsn021_33120	COG0632	four-way junction helicase activity
acsn021_33150	COG1131	(ABC) transporter
acsn021_33170	COG2197	response regulator
acsn021_33190	COG4608	Belongs to the ABC transporter superfamily
acsn021_33190	COG4608	Belongs to the ABC transporter superfamily
acsn021_33200	COG0444	Belongs to the ABC transporter superfamily
acsn021_33220	COG0601	transmembrane transport
acsn021_33230	COG0747	negative chemotaxis
acsn021_33250	COG1307	EDD domain protein, DegV family
acsn021_33260	COG1116	anion transmembrane transporter activity
acsn021_33300	COG1116	anion transmembrane transporter activity
acsn021_33310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
acsn021_33380	COG1523	belongs to the glycosyl hydrolase 13 family
acsn021_33410	COG1132	(ABC) transporter
acsn021_33450	COG1131	(ABC) transporter
acsn021_33460	COG0488	(ABC) transporter
acsn021_33500	COG4536	flavin adenine dinucleotide binding
acsn021_33530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
acsn021_33540	COG0167	dihydroorotate dehydrogenase activity
acsn021_33580	COG0463	Glycosyl transferase, family 2
acsn021_33600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
acsn021_33610	COG0006	proline dipeptidase activity
acsn021_33620	COG0626	cystathionine gamma-synthase activity
acsn021_33630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
acsn021_33640	COG0284	orotidine-5'-phosphate decarboxylase activity
acsn021_33690	COG2190	(PTS) system
acsn021_33690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_33690	COG1263	PTS System
acsn021_33710	COG0745	RESPONSE REGULATOR receiver
acsn021_33720	COG5002	protein histidine kinase activity
acsn021_33780	COG1115	amino acid carrier protein
acsn021_33810	COG2207	Transcriptional regulator
acsn021_33810	COG3708	Transcriptional regulator
acsn021_33830	COG1476	TRANSCRIPTIONal
acsn021_33850	COG3708	Transcriptional regulator
acsn021_33850	COG2207	Transcriptional regulator
acsn021_33950	COG2207	Transcriptional regulator
acsn021_33980	COG4978	Transcriptional regulator
acsn021_33980	COG0789	Transcriptional regulator
acsn021_33990	COG5297	Belongs to the glycosyl hydrolase family 6
acsn021_34020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
acsn021_34040	COG0018	arginyl-trna synthetase
acsn021_34120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
acsn021_34130	COG0318	PFAM AMP-dependent synthetase and ligase
acsn021_34150	COG1917	Cupin 2, conserved barrel domain protein
acsn021_34150	COG2207	Transcriptional regulator
acsn021_34160	COG1132	(ABC) transporter
acsn021_34170	COG1132	(ABC) transporter
acsn021_34180	COG0737	Belongs to the 5'-nucleotidase family
acsn021_34220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
acsn021_34250	COG0583	DNA-binding transcription factor activity
acsn021_34360	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_34390	COG0395	ABC-type sugar transport system, permease component
acsn021_34400	COG4209	transmembrane transport
acsn021_34410	COG4753	response regulator
acsn021_34410	COG2207	Transcriptional regulator
acsn021_34420	COG2972	Histidine kinase
acsn021_34440	COG1501	Belongs to the glycosyl hydrolase 31 family
acsn021_34490	COG0626	cystathionine gamma-synthase activity
acsn021_34500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
acsn021_34510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
acsn021_34590	COG1285	pathogenesis
acsn021_34600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
acsn021_34610	COG1802	Transcriptional regulator
acsn021_34670	COG1151	hydroxylamine reductase activity
acsn021_34680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
acsn021_34700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
acsn021_34720	COG1328	CTP reductase activity
acsn021_34720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
acsn021_34730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
acsn021_34770	COG0640	Transcriptional regulator
acsn021_34780	COG0673	inositol 2-dehydrogenase activity
acsn021_34790	COG0673	inositol 2-dehydrogenase activity
acsn021_34800	COG1082	Xylose isomerase domain protein TIM barrel
acsn021_34850	COG2207	Transcriptional regulator
acsn021_34850	COG4753	response regulator
acsn021_34860	COG2972	Histidine kinase
acsn021_34880	COG0395	ABC-type sugar transport system, permease component
acsn021_34890	COG4209	transmembrane transport
acsn021_34900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
acsn021_34910	COG0248	Ppx GppA phosphatase
acsn021_34940	COG1113	amino acid transport
acsn021_34950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
acsn021_34960	COG0583	DNA-binding transcription factor activity
acsn021_35040	COG3845	ABC transporter
acsn021_35060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
acsn021_35070	COG1609	Transcriptional regulator
acsn021_35220	COG3708	Transcriptional regulator
acsn021_35220	COG2207	Transcriptional regulator
acsn021_35240	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
acsn021_35250	COG0493	'glutamate synthase
acsn021_35280	COG1132	(ABC) transporter
acsn021_35360	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_35390	COG0148	phosphopyruvate hydratase activity
acsn021_35410	COG0475	glutathione-regulated potassium exporter activity
acsn021_35440	COG4555	ABC transporter
acsn021_35470	COG0024	Methionine aminopeptidase
acsn021_35550	COG0745	RESPONSE REGULATOR receiver
acsn021_35570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
acsn021_35580	COG3958	Transketolase
acsn021_35590	COG3959	Transketolase, thiamine diphosphate binding domain
acsn021_35610	COG1609	Transcriptional regulator
acsn021_35640	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
acsn021_35660	COG1132	(ABC) transporter
acsn021_35670	COG1132	(ABC) transporter
acsn021_35700	COG1476	TRANSCRIPTIONal
acsn021_35730	COG3639	organic phosphonate transmembrane transporter activity
acsn021_35740	COG3639	organic phosphonate transmembrane transporter activity
acsn021_35770	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
acsn021_35780	COG1609	Transcriptional regulator
acsn021_35790	COG1053	succinate dehydrogenase
acsn021_35820	COG0484	heat shock protein binding
acsn021_35850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
acsn021_35860	COG0488	(ABC) transporter
acsn021_35900	COG3973	AAA domain
acsn021_35920	COG0656	L-ascorbic acid biosynthetic process
acsn021_35940	COG1131	(ABC) transporter
acsn021_35960	COG0312	modulator of DNA gyrase
acsn021_35980	COG3250	beta-galactosidase activity
acsn021_36050	COG3842	ATPase activity
acsn021_36110	COG2378	regulation of single-species biofilm formation
acsn021_36120	COG1132	(ABC) transporter
acsn021_36130	COG4988	ABC transporter
acsn021_36140	COG2832	Protein of unknown function (DUF454)
acsn021_36170	COG0701	Predicted permease
acsn021_36180	COG0523	cobalamin synthesis protein
acsn021_36190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
acsn021_36200	COG1121	(ABC) transporter
acsn021_36210	COG0803	Belongs to the bacterial solute-binding protein 9 family
acsn021_36260	COG0735	belongs to the Fur family
acsn021_36300	COG0298	carbon dioxide binding
acsn021_36390	COG0406	alpha-ribazole phosphatase activity
acsn021_36400	COG3290	protein histidine kinase activity
acsn021_36400	COG0840	transmembrane signaling receptor activity
acsn021_36420	COG2706	6-phosphogluconolactonase activity
acsn021_36480	COG0395	ABC-type sugar transport system, permease component
acsn021_36490	COG4209	transmembrane transport
acsn021_36500	COG1609	Transcriptional regulator
acsn021_36520	COG0741	lytic transglycosylase activity
acsn021_36550	COG1609	Transcriptional regulator
acsn021_36570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
acsn021_36570	COG0426	domain, Protein
acsn021_36620	COG2033	superoxide reductase activity
acsn021_36640	COG1773	rubredoxin
acsn021_36650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
acsn021_36660	COG1803	Methylglyoxal synthase
acsn021_36670	COG0372	Belongs to the citrate synthase family
acsn021_36690	COG3833	ABC-type maltose transport systems, permease component
acsn021_36700	COG1175	transmembrane transport
acsn021_36720	COG1917	Cupin 2, conserved barrel domain protein
acsn021_36720	COG2207	Transcriptional regulator
acsn021_36730	COG1609	Transcriptional regulator
acsn021_36780	COG0825	malonyl-CoA metabolic process
acsn021_36790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
acsn021_36800	COG0439	Biotin carboxylase
acsn021_36820	COG0511	ligase activity, forming carbon-carbon bonds
acsn021_36830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
acsn021_36840	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_36850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
acsn021_36860	COG2070	2-Nitropropane dioxygenase
acsn021_36870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_36900	COG1396	sequence-specific DNA binding
acsn021_36930	COG0653	protein targeting
acsn021_36960	COG1132	(ABC) transporter
acsn021_36970	COG1132	(ABC) transporter
acsn021_36980	COG1773	rubredoxin
acsn021_36980	COG1592	Rubrerythrin
acsn021_36990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
acsn021_37000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
acsn021_37010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
acsn021_37030	COG5566	PFAM Mor transcription activator
acsn021_37060	COG1511	domain protein
acsn021_37070	COG1959	2 iron, 2 sulfur cluster binding
acsn021_37080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
acsn021_37110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
acsn021_37130	COG1739	Uncharacterized protein family UPF0029
acsn021_37170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
acsn021_37270	COG0525	valine-tRNA ligase activity
acsn021_37320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
acsn021_37400	COG0367	asparagine synthase
acsn021_37530	COG1250	3-hydroxyacyl-CoA dehydrogenase
acsn021_37630	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
acsn021_37650	COG3401	FG-GAP repeat protein
acsn021_37660	COG1653	transport
acsn021_37670	COG0395	ABC-type sugar transport system, permease component
acsn021_37680	COG4209	transmembrane transport
acsn021_37690	COG2207	Transcriptional regulator
acsn021_37700	COG2755	lipolytic protein G-D-S-L family
acsn021_37710	COG3401	FG-GAP repeat protein
acsn021_37730	COG1683	Conserved Protein
acsn021_37740	COG0756	dUTP diphosphatase activity
acsn021_37750	COG0583	DNA-binding transcription factor activity
acsn021_37770	COG2388	GCN5-related N-acetyl-transferase
acsn021_37790	COG0840	transmembrane signaling receptor activity
acsn021_37810	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_37840	COG1012	belongs to the aldehyde dehydrogenase family
acsn021_37850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
acsn021_37860	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
acsn021_37870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
acsn021_37890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
acsn021_37910	COG2226	methyltransferase
acsn021_37930	COG1070	Carbohydrate kinase
acsn021_37980	COG1597	lipid kinase activity
acsn021_38000	COG0840	transmembrane signaling receptor activity
acsn021_38010	COG1074	ATP-dependent DNA helicase activity
acsn021_38020	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
acsn021_38040	COG1307	EDD domain protein, DegV family
acsn021_38070	COG5002	protein histidine kinase activity
acsn021_38070	COG3850	Histidine kinase
acsn021_38080	COG0745	RESPONSE REGULATOR receiver
acsn021_38100	COG2268	Band 7 protein
acsn021_38130	COG0138	bifunctional purine biosynthesis protein purh
acsn021_38150	COG5002	protein histidine kinase activity
acsn021_38160	COG0745	RESPONSE REGULATOR receiver
acsn021_38170	COG0704	Plays a role in the regulation of phosphate uptake
acsn021_38180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
acsn021_38190	COG0581	inorganic phosphate transmembrane transporter activity
acsn021_38200	COG0573	inorganic phosphate transmembrane transporter activity
acsn021_38210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
acsn021_38250	COG0516	GMP reductase activity
acsn021_38250	COG0517	IMP dehydrogenase activity
acsn021_38270	COG0459	protein refolding
acsn021_38280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
acsn021_38320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
acsn021_38330	COG0436	Aminotransferase
acsn021_38380	COG0411	ABC transporter
acsn021_38450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
acsn021_38470	COG1316	TRANSCRIPTIONal
acsn021_38480	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
acsn021_38500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
acsn021_38510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
acsn021_38540	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
acsn021_38570	COG0840	transmembrane signaling receptor activity
acsn021_38590	COG0641	radical SAM
acsn021_38600	COG3408	Glycogen debranching enzyme
acsn021_38600	COG3119	arylsulfatase activity
acsn021_38620	COG3119	arylsulfatase activity
acsn021_38630	COG4211	Belongs to the binding-protein-dependent transport system permease family
acsn021_38660	COG1129	ABC transporter
acsn021_38670	COG3119	arylsulfatase activity
acsn021_38680	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_38690	COG3119	arylsulfatase activity
acsn021_38700	COG2204	response regulator
acsn021_38710	COG3275	phosphorelay sensor kinase activity
acsn021_38750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
acsn021_38760	COG2207	Transcriptional regulator
acsn021_38770	COG0582	viral genome integration into host DNA
acsn021_38810	COG4584	PFAM Integrase catalytic
acsn021_38860	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
acsn021_38870	COG2226	methyltransferase
acsn021_39180	COG2003	Belongs to the UPF0758 family
acsn021_39340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
acsn021_39370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
acsn021_39440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
acsn021_39460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
acsn021_39460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
acsn021_39460	COG1013	pyruvate-flavodoxin oxidoreductase activity
acsn021_39460	COG0674	pyruvate-flavodoxin oxidoreductase activity
acsn021_39490	COG0745	RESPONSE REGULATOR receiver
acsn021_39500	COG2205	protein histidine kinase activity
acsn021_39520	COG0840	transmembrane signaling receptor activity
acsn021_39550	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
acsn021_39560	COG1492	cobalamin metabolic process
acsn021_39570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
acsn021_39610	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
acsn021_39630	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
acsn021_39640	COG1797	cobyrinic acid a,c-diamide synthase activity
acsn021_39700	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
acsn021_39760	COG0310	cobalt ion transport
acsn021_39790	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_39810	COG0395	ABC-type sugar transport system, permease component
acsn021_39820	COG4209	transmembrane transport
acsn021_39850	COG2755	lipolytic protein G-D-S-L family
acsn021_39870	COG0824	Thioesterase
acsn021_39900	COG0584	glycerophosphoryl diester phosphodiesterase
acsn021_39910	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
acsn021_39920	COG1278	Cold shock
acsn021_39950	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
acsn021_40020	COG4209	transmembrane transport
acsn021_40030	COG0395	ABC-type sugar transport system, permease component
acsn021_40050	COG0129	dihydroxy-acid dehydratase activity
acsn021_40070	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_40080	COG5426	von Willebrand factor, type A
acsn021_40090	COG2340	Cysteine-rich secretory protein family
acsn021_40110	COG1132	(ABC) transporter
acsn021_40120	COG1132	(ABC) transporter
acsn021_40130	COG1032	radical SAM domain protein
acsn021_40140	COG3655	Transcriptional regulator
acsn021_40170	COG1671	Belongs to the UPF0178 family
acsn021_40190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_40200	COG0601	transmembrane transport
acsn021_40210	COG0747	negative chemotaxis
acsn021_40220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
acsn021_40230	COG3459	Glycosyltransferase 36 associated
acsn021_40280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
acsn021_40290	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
acsn021_40320	COG0840	transmembrane signaling receptor activity
acsn021_40330	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
acsn021_40330	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
acsn021_40340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
acsn021_40360	COG1368	sulfuric ester hydrolase activity
acsn021_40390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
acsn021_40410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
acsn021_40420	COG2890	protein-(glutamine-N5) methyltransferase activity
acsn021_40430	COG3872	metal-dependent enzyme
acsn021_40440	COG0254	rRNA binding
acsn021_40450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
acsn021_40460	COG0281	malic enzyme
acsn021_40470	COG1242	4 iron, 4 sulfur cluster binding
acsn021_40490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
acsn021_40500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
acsn021_40510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
acsn021_40530	COG0544	peptidyl-prolyl cis-trans isomerase activity
acsn021_40540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
acsn021_40560	COG1115	amino acid carrier protein
acsn021_40580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
acsn021_40600	COG4603	Belongs to the binding-protein-dependent transport system permease family
acsn021_40610	COG3845	ABC transporter
acsn021_40630	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
acsn021_40660	COG3328	transposase activity
acsn021_40670	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
acsn021_40700	COG0402	S-adenosylhomocysteine deaminase activity
acsn021_40730	COG1733	regulation of RNA biosynthetic process
acsn021_40750	COG1216	Glycosyl transferase, family 2
acsn021_40760	COG0596	Alpha beta hydrolase
acsn021_40860	COG2337	Toxic component of a toxin-antitoxin (TA) module
acsn021_40890	COG1136	(ABC) transporter
acsn021_40910	COG0745	RESPONSE REGULATOR receiver
acsn021_40950	COG1136	(ABC) transporter
acsn021_40960	COG2205	protein histidine kinase activity
acsn021_40970	COG0745	RESPONSE REGULATOR receiver
acsn021_41150	COG1196	nuclear chromosome segregation
acsn021_41150	COG0741	lytic transglycosylase activity
acsn021_41150	COG0739	heme binding
acsn021_41170	COG1053	succinate dehydrogenase
acsn021_41170	COG3976	FMN-binding domain protein
acsn021_41220	COG0798	PFAM Bile acid sodium symporter
acsn021_41430	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
acsn021_41450	COG2088	sporulation resulting in formation of a cellular spore
acsn021_41550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
acsn021_41560	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_41560	COG2247	cell wall binding repeat
acsn021_41570	COG0116	Belongs to the methyltransferase superfamily
acsn021_41600	COG1132	(ABC) transporter
acsn021_41610	COG1132	(ABC) transporter
acsn021_41620	COG3290	protein histidine kinase activity
acsn021_41630	COG3279	Response regulator of the LytR AlgR family
acsn021_41650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
acsn021_41680	COG1234	tRNA 3'-trailer cleavage
acsn021_41710	COG1214	PFAM Peptidase M22, glycoprotease
acsn021_41720	COG0802	atpase or kinase
acsn021_41740	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
acsn021_41770	COG1132	(ABC) transporter
acsn021_41820	COG3944	biosynthesis protein
acsn021_41830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
acsn021_41880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
acsn021_41900	COG2183	response to ionizing radiation
acsn021_41910	COG2116	formate transmembrane transporter activity
acsn021_41930	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
acsn021_41940	COG0460	homoserine dehydrogenase
acsn021_41950	COG4492	Belongs to the UPF0735 family
acsn021_41970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
acsn021_41990	COG0653	protein targeting
acsn021_42070	COG0251	oxidation-reduction process
acsn021_42090	COG2996	Protein conserved in bacteria
acsn021_42110	COG1040	competence protein
acsn021_42130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
acsn021_42160	COG4786	Flagellar basal body rod
acsn021_42200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
acsn021_42210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
acsn021_42220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
acsn021_42230	COG0049	tRNA binding
acsn021_42240	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
acsn021_42270	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
acsn021_42280	COG0085	RNA polymerase activity
acsn021_42290	COG0222	ribosome binding
acsn021_42310	COG0081	regulation of translation
acsn021_42320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
acsn021_42330	COG0250	Participates in transcription elongation, termination and antitermination
acsn021_42350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
acsn021_42360	COG0395	ABC-type sugar transport system, permease component
acsn021_42370	COG1175	transmembrane transport
acsn021_42390	COG1609	Transcriptional regulator
acsn021_42410	COG2878	Part of a membrane complex involved in electron transport
acsn021_42420	COG4657	Part of a membrane complex involved in electron transport
acsn021_42430	COG4660	Part of a membrane complex involved in electron transport
acsn021_42440	COG4659	FMN binding
acsn021_42450	COG4658	electron transport chain
acsn021_42460	COG4656	Part of a membrane complex involved in electron transport
acsn021_42470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
acsn021_42530	COG1725	Transcriptional regulator
acsn021_42540	COG2252	PERMEase
acsn021_42550	COG0598	Magnesium transport protein CorA
acsn021_42590	COG1609	Transcriptional regulator
acsn021_42610	COG1609	Transcriptional regulator
acsn021_42630	COG1477	protein flavinylation
acsn021_42640	COG4656	Part of a membrane complex involved in electron transport
acsn021_42650	COG4658	electron transport chain
acsn021_42690	COG2814	Major facilitator Superfamily
acsn021_42700	COG3711	transcriptional antiterminator
acsn021_42710	COG2723	6-phospho-beta-galactosidase activity
acsn021_42720	COG1263	PTS System
acsn021_42720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_42720	COG2190	(PTS) system
acsn021_42750	COG1490	D-aminoacyl-tRNA deacylase activity
acsn021_42760	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
acsn021_42780	COG0463	Glycosyl transferase, family 2
acsn021_42800	COG2309	aminopeptidase activity
acsn021_42870	COG0698	ribose 5-phosphate isomerase
acsn021_42880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
acsn021_42890	COG0009	L-threonylcarbamoyladenylate synthase
acsn021_42900	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_42940	COG4862	establishment of competence for transformation
acsn021_42970	COG0789	Transcriptional regulator
acsn021_42980	COG0305	Participates in initiation and elongation during chromosome replication
acsn021_42990	COG0359	binds to the 23S rRNA
acsn021_43000	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
acsn021_43050	COG1442	glycosyl transferase family 8
acsn021_43050	COG1216	Glycosyl transferase, family 2
acsn021_43060	COG0438	transferase activity, transferring glycosyl groups
acsn021_43090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
acsn021_43140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
acsn021_43160	COG3103	Sh3 type 3 domain protein
acsn021_43160	COG0366	Alpha amylase catalytic
acsn021_43180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
acsn021_43190	COG0629	single-stranded DNA binding
acsn021_43200	COG0360	Binds together with S18 to 16S ribosomal RNA
acsn021_43220	COG1136	(ABC) transporter
acsn021_43230	COG2070	2-Nitropropane dioxygenase
acsn021_43240	COG0668	transmembrane transport
acsn021_43250	COG0659	secondary active sulfate transmembrane transporter activity
acsn021_43290	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_43350	COG0395	ABC-type sugar transport system, permease component
acsn021_43360	COG4209	transmembrane transport
acsn021_43380	COG3534	alpha-L-arabinofuranosidase
acsn021_43390	COG1940	carbohydrate kinase activity
acsn021_43400	COG4481	Protein conserved in bacteria
acsn021_43430	COG1592	Rubrerythrin
acsn021_43430	COG1773	rubredoxin
acsn021_43440	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
acsn021_43450	COG2942	2-epimerase
acsn021_43480	COG0513	Belongs to the DEAD box helicase family
acsn021_43520	COG1363	Peptidase, m42
acsn021_43530	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
acsn021_43540	COG0708	Exodeoxyribonuclease III
acsn021_43670	COG1131	(ABC) transporter
acsn021_43690	COG1357	PFAM Pentapeptide repeats (8 copies)
acsn021_43700	COG0745	RESPONSE REGULATOR receiver
acsn021_43710	COG5002	protein histidine kinase activity
acsn021_43820	COG0789	Transcriptional regulator
acsn021_43830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
acsn021_43900	COG0800	Aldolase
acsn021_43960	COG0840	transmembrane signaling receptor activity
acsn021_44020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
acsn021_44030	COG3344	reverse transcriptase
acsn021_44040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
acsn021_44050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
acsn021_44060	COG1827	regulation of RNA biosynthetic process
acsn021_44100	COG0166	Belongs to the GPI family
acsn021_44150	COG0778	Nitroreductase
acsn021_44200	COG0745	RESPONSE REGULATOR receiver
acsn021_44210	COG5002	protein histidine kinase activity
acsn021_44220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
acsn021_44230	COG3437	response regulator, receiver
acsn021_44250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
acsn021_44330	COG0590	tRNA wobble adenosine to inosine editing
acsn021_44380	COG3458	cephalosporin-C deacetylase activity
acsn021_44410	COG0395	ABC-type sugar transport system, permease component
acsn021_44420	COG4209	transmembrane transport
acsn021_44430	COG3459	Glycosyltransferase 36 associated
acsn021_44460	COG0488	(ABC) transporter
acsn021_44480	COG0602	queuosine metabolic process
acsn021_44490	COG0205	6-phosphofructokinase activity
acsn021_44500	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_44520	COG0395	ABC-type sugar transport system, permease component
acsn021_44530	COG4209	transmembrane transport
acsn021_44540	COG2207	Transcriptional regulator
acsn021_44540	COG0662	Cupin 2, conserved barrel domain protein
acsn021_44580	COG2207	Transcriptional regulator
acsn021_44580	COG1609	Transcriptional regulator
acsn021_44590	COG2755	lipolytic protein G-D-S-L family
acsn021_44600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
acsn021_44610	COG0084	hydrolase, TatD family'
acsn021_44640	COG3546	catalase activity
acsn021_44680	COG0785	Cytochrome C biogenesis protein
acsn021_44730	COG1131	(ABC) transporter
acsn021_44740	COG0656	L-ascorbic acid biosynthetic process
acsn021_44750	COG0700	Nucleoside recognition
acsn021_44760	COG2715	membrane protein required for spore maturation
acsn021_44770	COG2002	toxin-antitoxin pair type II binding
acsn021_44780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
acsn021_44790	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
acsn021_44800	COG1774	PSP1 C-terminal conserved region
acsn021_44810	COG0470	DNA polymerase III
acsn021_44820	COG1728	Protein conserved in bacteria
acsn021_44830	COG0194	GDP metabolic process
acsn021_44840	COG1982	Orn Lys Arg decarboxylase major
acsn021_44880	COG3279	Response regulator of the LytR AlgR family
acsn021_44950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
acsn021_44980	COG1269	ATP hydrolysis coupled proton transport
acsn021_45040	COG1394	ATPase activity, coupled to movement of substances
acsn021_45060	COG1609	Transcriptional regulator
acsn021_45070	COG1069	ribulokinase activity
acsn021_45090	COG0235	Class ii aldolase
acsn021_45100	COG1686	Belongs to the peptidase S11 family
acsn021_45140	COG1012	belongs to the aldehyde dehydrogenase family
acsn021_45140	COG1454	alcohol dehydrogenase
acsn021_45160	COG1475	DNA binding
acsn021_45170	COG1192	Involved in chromosome partitioning
acsn021_45180	COG2197	response regulator
acsn021_45210	COG0357	Ribosomal RNA small subunit methyltransferase G
acsn021_45220	COG0445	tRNA wobble uridine modification
acsn021_45230	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
acsn021_45240	COG1847	R3H domain protein
acsn021_45250	COG0706	membrane insertase activity
acsn021_45260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
acsn021_45270	COG0594	ribonuclease P activity
acsn021_45280	COG0230	Belongs to the bacterial ribosomal protein bL34 family