locus-tag	class	description
STSP2_00004	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
STSP2_00009	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
STSP2_00014	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
STSP2_00015	ENOG4108094	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
STSP2_00016	ENOG4105BZU	Histidine kinase
STSP2_00017	ENOG4105CBS	Chea signal transduction histidine kinase
STSP2_00018	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
STSP2_00019	ENOG4105C11	sulfate adenylyltransferase), subunit 2
STSP2_00021	ENOG4107RDJ	Sulfotransferase
STSP2_00022	ENOG4105MQ3	flagellar protein FliS
STSP2_00023	ENOG4105I03	Flagellin
STSP2_00026	ENOG4108VYJ	response regulator receiver protein
STSP2_00031	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
STSP2_00032	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
STSP2_00038	ENOG4105E14	MotA TolQ exbB proton channel
STSP2_00039	ENOG4105ER2	Ompa motb domain protein
STSP2_00042	ENOG4105CN7	Flagellar biosynthetic protein FliP
STSP2_00043	ENOG4105VS8	Flagellar biosynthetic protein fliq
STSP2_00044	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
STSP2_00045	ENOG4105D00	flagellar biosynthetic protein flhB
STSP2_00047	ENOG4105D7B	Flagellar biosynthesis protein flha
STSP2_00048	ENOG4107VE5	flagellar hook-associated protein
STSP2_00056	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
STSP2_00057	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
STSP2_00058	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
STSP2_00059	ENOG4105CGA	flagellar basal-body rod protein FlgG
STSP2_00060	ENOG4108JQA	flagellar
STSP2_00062	ENOG4105BZE	flagellar hook protein, FlgE
STSP2_00064	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
STSP2_00067	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
STSP2_00070	ENOG4105DD5	Flagellar motor switch protein
STSP2_00071	ENOG4105D7B	Flagellar biosynthesis protein flha
STSP2_00073	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
STSP2_00080	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
STSP2_00081	ENOG4105ENH	Sulfatase
STSP2_00082	ENOG4105C1A	potassium transporter peripheral membrane
STSP2_00083	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
STSP2_00084	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
STSP2_00088	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
STSP2_00094	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
STSP2_00095	ENOG4105DWV	Homoserine O-trans-acetylase
STSP2_00097	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
STSP2_00100	ENOG4108YZG	isomerase
STSP2_00102	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
STSP2_00104	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
STSP2_00116	ENOG4105C02	permease
STSP2_00119	ENOG41061MV	Arylsulfatase
STSP2_00120	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
STSP2_00126	ENOG4105CBG	Sulfatase
STSP2_00132	ENOG4105EJ9	Membrane
STSP2_00139	ENOG4105BZU	Histidine kinase
STSP2_00142	ENOG4105DVT	helicase
STSP2_00144	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
STSP2_00145	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
STSP2_00149	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
STSP2_00155	ENOG4105MRR	Transcriptional regulator (By similarity)
STSP2_00156	ENOG4105PGM	cation diffusion facilitator family transporter
STSP2_00159	ENOG4105HEE	Binding Domain protein
STSP2_00162	ENOG41061MV	Arylsulfatase
STSP2_00163	ENOG4107QSN	dihydrolipoamide acetyltransferase
STSP2_00164	ENOG4105E2D	ec 3.2.1.52
STSP2_00166	ENOG4107QJE	Chromosome Partitioning Protein
STSP2_00173	ENOG4105BZU	Histidine kinase
STSP2_00175	ENOG4107SDT	Homocitrate synthase
STSP2_00177	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
STSP2_00190	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
STSP2_00193	ENOG4105E2D	ec 3.2.1.52
STSP2_00203	ENOG4107QNG	Phosphoribosylglycinamide synthetase
STSP2_00210	ENOG4105CNI	cell division protein FtsW
STSP2_00215	ENOG4105CFG	Acts as a chaperone (By similarity)
STSP2_00216	ENOG41066A3	ATP guanido phosphotransferase
STSP2_00223	ENOG4107R3N	Filamentation induced by cAMP protein fic
STSP2_00224	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
STSP2_00226	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
STSP2_00227	ENOG4105C9U	ATP-dependent DNA helicase RecQ
STSP2_00230	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
STSP2_00231	ENOG4105E0X	reductase
STSP2_00233	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
STSP2_00234	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
STSP2_00240	ENOG4107QKV	phosphomannomutase
STSP2_00241	ENOG4105C5X	domain protein
STSP2_00244	ENOG4105VEQ	Cold shock protein
STSP2_00264	ENOG4105BZU	Histidine kinase
STSP2_00265	ENOG4105C0A	alcohol dehydrogenase
STSP2_00268	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
STSP2_00270	ENOG4105CNA	YD repeat protein
STSP2_00272	ENOG4105CNA	YD repeat protein
STSP2_00275	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
STSP2_00276	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
STSP2_00277	ENOG4107QJE	Chromosome Partitioning Protein
STSP2_00278	ENOG4105E98	transcriptional regulator DeoR family
STSP2_00285	ENOG4108UXE	Protein tyrosine phosphatase
STSP2_00288	ENOG4105F7P	transcriptional regulator AsnC family
STSP2_00292	ENOG4105CBX	hi0933 family
STSP2_00295	ENOG4108IYU	L-aspartate oxidase
STSP2_00297	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
STSP2_00298	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
STSP2_00310	ENOG4105CZN	Potassium uptake protein
STSP2_00312	ENOG4107ZYR	domain protein
STSP2_00313	ENOG4108KP7	hydrolase
STSP2_00315	ENOG4105C34	Pseudouridine synthase
STSP2_00321	ENOG4105BZU	Histidine kinase
STSP2_00322	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
STSP2_00324	ENOG4105F5P	DNA-damage-inducible protein d
STSP2_00327	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
STSP2_00342	ENOG4108URH	decarboxylase
STSP2_00347	ENOG4105ER2	Ompa motb domain protein
STSP2_00352	ENOG4105CEM	UPF0597 protein
STSP2_00357	ENOG4105CQC	Prephenate dehydratase
STSP2_00358	ENOG4105CP7	Triose-phosphate isomerase
STSP2_00360	ENOG4105DSJ	YicC domain protein
STSP2_00361	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
STSP2_00362	ENOG41063B5	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
STSP2_00363	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
STSP2_00364	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
STSP2_00367	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
STSP2_00368	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
STSP2_00372	ENOG4105EX0	alpha-galactosidase
STSP2_00384	ENOG4108R6K	riboflavin synthase, subunit alpha
STSP2_00385	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
STSP2_00386	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
STSP2_00391	ENOG4105CMM	transposase
STSP2_00398	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
STSP2_00400	ENOG4108FN7	Aldo keto reductase
STSP2_00403	ENOG4105C3M	thioredoxin reductase
STSP2_00406	ENOG4105FA0	parb-like partition protein
STSP2_00408	ENOG4105C0H	protease
STSP2_00411	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
STSP2_00413	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
STSP2_00414	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
STSP2_00415	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
STSP2_00420	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
STSP2_00422	ENOG4105C0H	protease
STSP2_00423	ENOG4105VN1	Heat shock protein
STSP2_00425	ENOG4105BZU	Histidine kinase
STSP2_00427	ENOG4105D05	Receptor
STSP2_00432	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
STSP2_00433	ENOG4108VAU	general secretion pathway protein G
STSP2_00434	ENOG4105KHS	type IV fimbrial pilin protein
STSP2_00435	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
STSP2_00436	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
STSP2_00437	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
STSP2_00438	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
STSP2_00439	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
STSP2_00444	ENOG4105DKW	ABC transporter
STSP2_00445	ENOG4105C8V	SAICAR synthetase
STSP2_00446	ENOG4105CBG	Sulfatase
STSP2_00447	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
STSP2_00448	ENOG4105D22	carbon starvation protein
STSP2_00450	ENOG4105C8B	TIGR00159 family
STSP2_00453	ENOG4105C5H	ABC transporter
STSP2_00454	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
STSP2_00456	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
STSP2_00459	ENOG4105CNU	cell division protein FtsK
STSP2_00460	ENOG4105DE4	1-phosphofructokinase
STSP2_00461	ENOG4107QX9	Thiol disulfide interChange protein
STSP2_00462	ENOG4105E2D	ec 3.2.1.52
STSP2_00468	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
STSP2_00469	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
STSP2_00471	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
STSP2_00472	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
STSP2_00473	ENOG4108UUM	single-stranded DNA-binding protein
STSP2_00475	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
STSP2_00476	ENOG4105CDU	Replicative dna helicase
STSP2_00477	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
STSP2_00480	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
STSP2_00482	ENOG4106448	streptomycin biosynthesis protein strI
STSP2_00484	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
STSP2_00486	ENOG41061MV	Arylsulfatase
STSP2_00487	ENOG41061MV	Arylsulfatase
STSP2_00489	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
STSP2_00494	ENOG41083MR	nifu domain-containing protein
STSP2_00495	ENOG4105C7K	acetolactate synthase
STSP2_00497	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
STSP2_00500	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
STSP2_00501	ENOG4105D0M	Protease HtpX homolog
STSP2_00503	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
STSP2_00504	ENOG4105D6A	Electron transport complex
STSP2_00506	ENOG4105DZB	Electron transport complex
STSP2_00507	ENOG4105DGN	Electron transport complex
STSP2_00508	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
STSP2_00510	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
STSP2_00523	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
STSP2_00525	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
STSP2_00526	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
STSP2_00527	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
STSP2_00528	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
STSP2_00529	ENOG4105G5W	regulator Fur family
STSP2_00537	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
STSP2_00543	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
STSP2_00550	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
STSP2_00551	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
STSP2_00552	ENOG4105CAT	Cytidine monophosphate kinase
STSP2_00553	ENOG4107SGM	protein serine threonine phosphatase
STSP2_00554	ENOG410855V	Acylphosphatase
STSP2_00555	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
STSP2_00556	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
STSP2_00558	ENOG4106AM8	polysaccharide lyase family 8
STSP2_00559	ENOG4107SET	aldo keto reductase
STSP2_00560	ENOG4108UXN	response regulator
STSP2_00561	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
STSP2_00562	ENOG4105D41	biosynthesis protein thiH
STSP2_00563	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
STSP2_00566	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
STSP2_00567	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
STSP2_00568	ENOG4105C6E	dna polymerase iii
STSP2_00569	ENOG4105EPC	oxidoreductase
STSP2_00570	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
STSP2_00574	ENOG4105C26	Dehydrogenase
STSP2_00582	ENOG4105G6Z	alkaline phosphatase
STSP2_00583	ENOG4105CNA	YD repeat protein
STSP2_00585	ENOG4105CNA	YD repeat protein
STSP2_00589	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
STSP2_00590	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
STSP2_00591	ENOG4105C10	Electron transfer flavoprotein
STSP2_00592	ENOG4108Q52	Methyltransferase cognate corrinoid protein
STSP2_00593	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
STSP2_00596	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
STSP2_00598	ENOG4105II7	pyrroline-5-carboxylate reductase
STSP2_00599	ENOG4105CS1	NAD(P)H quinone oxidoreductase
STSP2_00600	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
STSP2_00605	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
STSP2_00606	ENOG4108UJD	30S ribosomal protein S9
STSP2_00607	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
STSP2_00608	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
STSP2_00615	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
STSP2_00627	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
STSP2_00628	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
STSP2_00634	ENOG4105VEQ	Cold shock protein
STSP2_00637	ENOG4105VEQ	Cold shock protein
STSP2_00640	ENOG4105EUZ	Beta-lactamase domain protein
STSP2_00657	ENOG4107U9B	transcriptional regulator
STSP2_00660	ENOG4105C1J	atp-dependent rna helicase
STSP2_00662	ENOG4105VDW	Csbd family
STSP2_00663	ENOG4105C8Q	Methyl-accepting chemotaxis
STSP2_00665	ENOG4105BZU	Histidine kinase
STSP2_00666	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
STSP2_00667	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
STSP2_00669	ENOG4105C75	arginyL-tRNA synthetase
STSP2_00670	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
STSP2_00674	ENOG4105DFA	alanine racemase domain protein
STSP2_00675	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
STSP2_00680	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
STSP2_00686	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
STSP2_00689	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
STSP2_00690	ENOG4105C45	hydrogenase expression formation protein (HypE)
STSP2_00691	ENOG4105CQS	hydrogenase expression formation protein HypD
STSP2_00696	ENOG4105CSM	endonuclease III
STSP2_00701	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
STSP2_00702	ENOG4105CVJ	phosphoglycerate mutase
STSP2_00704	ENOG4105EPD	Oligopeptide transporter, Opt family
STSP2_00705	ENOG4107PP3	Acetylornithine deacetylase
STSP2_00708	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
STSP2_00709	ENOG4105MA4	psp1 domain protein
STSP2_00711	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
STSP2_00713	ENOG4105C0B	DNA polymerase III (alpha subunit)
STSP2_00720	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
STSP2_00722	ENOG41061MV	Arylsulfatase
STSP2_00723	ENOG4105CBG	Sulfatase
STSP2_00724	ENOG4107QI1	Mate efflux family protein
STSP2_00725	ENOG4105BZW	Glycerate kinase
STSP2_00726	ENOG41061MV	Arylsulfatase
STSP2_00728	ENOG41061MV	Arylsulfatase
STSP2_00730	ENOG4105D7N	magnesium and cobalt transport protein CorA
STSP2_00731	ENOG4108U5N	UPF0316 protein
STSP2_00732	ENOG4107QSV	RmuC domain protein
STSP2_00737	ENOG41061MV	Arylsulfatase
STSP2_00738	ENOG4105CNT	hydrolase family 2
STSP2_00748	ENOG4105CPC	Aldo Keto reductase
STSP2_00750	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
STSP2_00752	ENOG410841Q	phosphoesterase PA-phosphatase related protein
STSP2_00753	ENOG4108UW5	maltose o-acetyltransferase
STSP2_00759	ENOG4105C01	Dihydroxy-acid dehydratase
STSP2_00764	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
STSP2_00766	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
STSP2_00769	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
STSP2_00770	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
STSP2_00771	ENOG4105KNE	Phosphatidate cytidylyltransferase
STSP2_00772	ENOG4105C9A	Phoh family
STSP2_00773	ENOG4105CTJ	Metal Dependent Phosphohydrolase
STSP2_00778	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
STSP2_00779	ENOG4107YK1	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
STSP2_00780	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
STSP2_00781	ENOG4105C8N	cysteinyl-tRNA synthetase
STSP2_00782	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
STSP2_00783	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
STSP2_00784	ENOG4105CIH	Imidazole acetol-phosphate transaminase
STSP2_00785	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
STSP2_00786	ENOG4105DJV	ribulose-phosphate 3-epimerase
STSP2_00787	ENOG4105BZA	Phosphoglycerate kinase
STSP2_00788	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
STSP2_00789	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
STSP2_00792	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
STSP2_00796	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
STSP2_00798	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
STSP2_00801	ENOG4105CNI	cell division protein FtsW
STSP2_00802	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
STSP2_00805	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
STSP2_00807	ENOG4105ESV	Glycosyl transferase, family 4
STSP2_00809	ENOG4105CBG	Sulfatase
STSP2_00810	ENOG4105CDY	transcriptional regulatory protein
STSP2_00811	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
STSP2_00814	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
STSP2_00814	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
STSP2_00815	ENOG4105CHV	Transcription elongation factor NusA
STSP2_00817	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
STSP2_00818	ENOG4107UXT	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
STSP2_00823	ENOG4105E9Q	Acyl-transferase
STSP2_00824	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
STSP2_00825	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
STSP2_00827	ENOG4107GJV	short-chain dehydrogenase reductase
STSP2_00834	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
STSP2_00836	ENOG4106KS4	Sulfatase
STSP2_00837	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
STSP2_00838	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
STSP2_00845	ENOG4105D49	3-dehydroquinate synthase
STSP2_00846	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
STSP2_00847	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
STSP2_00855	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
STSP2_00857	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
STSP2_00862	ENOG4105C0H	protease
STSP2_00863	ENOG4105C0H	protease
STSP2_00865	ENOG4108S4H	thioesterase Superfamily protein
STSP2_00866	ENOG4105K46	50S ribosomal protein l27
STSP2_00869	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
STSP2_00870	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
STSP2_00871	ENOG4105C25	Primosomal protein n'
STSP2_00877	ENOG4108FN7	Aldo keto reductase
STSP2_00882	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
STSP2_00883	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
STSP2_00886	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
STSP2_00888	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
STSP2_00889	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
STSP2_00892	ENOG4108ZGY	Transcriptional regulator (AsnC family)
STSP2_00894	ENOG4105D52	delta-aminolevulinic acid dehydratase
STSP2_00895	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
STSP2_00896	ENOG4105EGD	dinuclear metal center protein, YbgI family
STSP2_00898	ENOG4105CRQ	synthase (Component I)
STSP2_00901	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
STSP2_00902	ENOG41082DI	50s ribosomal protein l31
STSP2_00906	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
STSP2_00907	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
STSP2_00908	ENOG4105EUJ	GTP cyclohydrolase i
STSP2_00910	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
STSP2_00912	ENOG4105BZU	Histidine kinase
STSP2_00913	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
STSP2_00918	ENOG4105CSA	Coproporphyrinogen iii oxidase
STSP2_00924	ENOG41081FY	multiple antibiotic resistance (MarC)-related
STSP2_00925	ENOG4108U5Y	In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin. It has been described in publications as the Sarkosyl- insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan
STSP2_00928	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
STSP2_00933	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
STSP2_00935	ENOG4105CHJ	isochorismatase hydrolase
STSP2_00936	ENOG4105EPH	radical SAM domain protein
STSP2_00941	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
STSP2_00972	ENOG4105E6M	Sulphatase-modifying factor protein
STSP2_00976	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
STSP2_00977	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
STSP2_00994	ENOG4105EKQ	RNA-directed DNA polymerase
STSP2_00995	ENOG4105D5G	Transposase
STSP2_00996	ENOG4108VAU	general secretion pathway protein G
STSP2_01006	ENOG4105M0C	cytoplasmic protein
STSP2_01010	ENOG4108IJ7	Glycine betaine
STSP2_01020	ENOG4108ZXC	Two component transcriptional regulator, luxr family
STSP2_01021	ENOG4108V3W	Chemotaxis protein, CheW
STSP2_01022	ENOG4105C8Q	Methyl-accepting chemotaxis
STSP2_01043	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
STSP2_01045	ENOG4105C11	sulfate adenylyltransferase), subunit 2
STSP2_01059	ENOG4105DEU	major facilitator superfamily
STSP2_01062	ENOG4105CMM	transposase
STSP2_01065	ENOG4105DZR	Type I site-specific deoxyribonuclease
STSP2_01070	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
STSP2_01074	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
STSP2_01078	ENOG4105CFI	type iii restriction protein res subunit
STSP2_01081	ENOG4108ES9	ParB domain protein nuclease
STSP2_01082	ENOG41086VY	Fic/DOC family
STSP2_01097	ENOG4107QJZ	Glycosyl transferase, family 2
STSP2_01116	ENOG4108C33	Resolvase
STSP2_01121	ENOG4105D9P	serine threonine protein kinase
STSP2_01124	ENOG4105BZU	Histidine kinase
STSP2_01130	ENOG4108YZ8	Superoxide reductase
STSP2_01131	ENOG4108KS2	transglutaminase domain protein
STSP2_01137	ENOG4105C2M	dna polymerase I
STSP2_01140	ENOG4105CBG	Sulfatase
STSP2_01141	ENOG4105EPC	oxidoreductase
STSP2_01145	ENOG4105DUX	Transporter
STSP2_01149	ENOG4105E2D	ec 3.2.1.52
STSP2_01150	ENOG4105EPC	oxidoreductase
STSP2_01152	ENOG4105CNT	hydrolase family 2
STSP2_01153	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
STSP2_01155	ENOG4105DKP	glycosyl transferase, family 9
STSP2_01165	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
STSP2_01166	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
STSP2_01167	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
STSP2_01172	ENOG4107QI1	Mate efflux family protein
STSP2_01181	ENOG4105E9K	Isocitrate dehydrogenase
STSP2_01186	ENOG4108VAU	general secretion pathway protein G
STSP2_01193	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
STSP2_01200	ENOG4108HPI	phosphatidate Cytidylyltransferase
STSP2_01201	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
STSP2_01202	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
STSP2_01204	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
STSP2_01207	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
STSP2_01210	ENOG4108C33	Resolvase
STSP2_01234	ENOG41061MV	Arylsulfatase
STSP2_01238	ENOG4105ECQ	AraC Family Transcriptional Regulator
STSP2_01244	ENOG4105CBG	Sulfatase
STSP2_01246	ENOG4105CBG	Sulfatase
STSP2_01263	ENOG4105CKB	glycosidase
STSP2_01270	ENOG41084AE	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
STSP2_01286	ENOG4105E3B	Multicopper oxidase
STSP2_01294	ENOG4105E2D	ec 3.2.1.52
STSP2_01298	ENOG4105EPC	oxidoreductase
STSP2_01300	ENOG4107QPV	Serine Threonine protein kinase
STSP2_01301	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
STSP2_01304	ENOG4108JA2	transcriptioN-repair coupling factor
STSP2_01308	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
STSP2_01309	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
STSP2_01310	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
STSP2_01312	ENOG4106855	Competence protein
STSP2_01313	ENOG4105ID8	Transcriptional regulator, ARAC family
STSP2_01314	ENOG4105ESP	cell wall surface anchor family protein
STSP2_01317	ENOG4105C5Z	peptidase
STSP2_01318	ENOG4108JUA	Transcriptional regulator
STSP2_01321	ENOG4105CEY	Amp-dependent synthetase and ligase
STSP2_01324	ENOG4108HGU	Histidine kinase
STSP2_01327	ENOG4107QHF	type ii secretion system protein e
STSP2_01328	ENOG4105D7Q	type ii secretion system
STSP2_01329	ENOG4108VAU	general secretion pathway protein G
STSP2_01337	ENOG4105GVR	general secretion pathway protein D
STSP2_01345	ENOG4105BZU	Histidine kinase
STSP2_01346	ENOG4105C8Q	Methyl-accepting chemotaxis
STSP2_01347	ENOG4108V3W	Chemotaxis protein, CheW
STSP2_01348	ENOG4107QHF	type ii secretion system protein e
STSP2_01352	ENOG41061MV	Arylsulfatase
STSP2_01353	ENOG41061MV	Arylsulfatase
STSP2_01354	ENOG41061MV	Arylsulfatase
STSP2_01362	ENOG4105KT5	UmuD protein
STSP2_01363	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
STSP2_01367	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
STSP2_01368	ENOG4105CIZ	coA-substrate-specific enzyme activase
STSP2_01371	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
STSP2_01374	ENOG4105EM7	Selenocysteine-specific translation elongation factor
STSP2_01383	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
STSP2_01387	ENOG4107QTH	restriction modification system DNA specificity domain
STSP2_01389	ENOG4105CVR	type I restriction-modification system
STSP2_01405	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
STSP2_01407	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
STSP2_01422	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
STSP2_01423	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
STSP2_01425	ENOG4105CBG	Sulfatase
STSP2_01426	ENOG4105E7U	AraC family transcriptional regulator
STSP2_01427	ENOG4105CNT	hydrolase family 2
STSP2_01430	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
STSP2_01431	ENOG4105EB3	Histidine kinase
STSP2_01433	ENOG4107QIZ	NADH dehydrogenase
STSP2_01434	ENOG4107QHI	-hydrogenase
STSP2_01435	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
STSP2_01437	ENOG4107QW8	radical SAM domain protein
STSP2_01438	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
STSP2_01439	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
STSP2_01445	ENOG4105DZS	Phenylacetate-CoA ligase
STSP2_01450	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
STSP2_01456	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
STSP2_01457	ENOG4105C8T	Leucyl-tRNA synthetase
STSP2_01459	ENOG4105CBD	Diacylglycerol kinase
STSP2_01460	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
STSP2_01461	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
STSP2_01463	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
STSP2_01464	ENOG4105C5I	Dehydrogenase
STSP2_01465	ENOG4105CIN	aminoacyl-histidine dipeptidase
STSP2_01467	ENOG4107R3N	Filamentation induced by cAMP protein fic
STSP2_01470	ENOG4108C33	Resolvase
STSP2_01474	ENOG4108ZXC	Two component transcriptional regulator, luxr family
STSP2_01480	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
STSP2_01483	ENOG4105ESV	Glycosyl transferase, family 4
STSP2_01484	ENOG4107QQG	Dehydrogenase
STSP2_01487	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
STSP2_01492	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
STSP2_01494	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
STSP2_01495	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
STSP2_01496	ENOG4108IAJ	Nad-dependent epimerase dehydratase
STSP2_01503	ENOG4107HQ7	repeat protein
STSP2_01508	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
STSP2_01510	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
STSP2_01512	ENOG4105DK0	Indole-3-glycerol phosphate synthase
STSP2_01514	ENOG4105CX6	glutaminyL-tRNA synthetase
STSP2_01515	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
STSP2_01516	ENOG4108MGF	sugar kinase
STSP2_01517	ENOG4105M7V	2'-5' rna ligase
STSP2_01518	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
STSP2_01519	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
STSP2_01525	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
STSP2_01527	ENOG4108URH	decarboxylase
STSP2_01530	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
STSP2_01533	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
STSP2_01535	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
STSP2_01536	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
STSP2_01539	ENOG4105C0P	Mg chelatase subunit ChlI
STSP2_01542	ENOG4105CBG	Sulfatase
STSP2_01546	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
STSP2_01551	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
STSP2_01552	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
STSP2_01556	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
STSP2_01557	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
STSP2_01559	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
STSP2_01560	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
STSP2_01561	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
STSP2_01562	ENOG41085TX	30S ribosomal protein S21
STSP2_01563	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
STSP2_01570	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
STSP2_01571	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
STSP2_01572	ENOG4107R21	site-determining protein
STSP2_01575	ENOG4105BZU	Histidine kinase
STSP2_01577	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
STSP2_01578	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
STSP2_01581	ENOG4105M8F	Biopolymer transport protein exbD tolR
STSP2_01582	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
STSP2_01587	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
STSP2_01600	ENOG4105CCT	upf0313 protein
STSP2_01615	ENOG4105DAN	ATP-dependent protease
STSP2_01617	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
STSP2_01619	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
STSP2_01625	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
STSP2_01627	ENOG4105CJ1	ABC, transporter
STSP2_01634	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
STSP2_01646	ENOG4105WG9	Conserved Protein
STSP2_01656	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
STSP2_01657	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
STSP2_01658	ENOG4108JJB	ABC transporter
STSP2_01663	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
STSP2_01674	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
STSP2_01677	ENOG41061MV	Arylsulfatase
STSP2_01681	ENOG4105C3G	gtp-binding protein
STSP2_01682	ENOG4105CEV	competence damage-inducible protein
STSP2_01683	ENOG4107QHF	type ii secretion system protein e
STSP2_01684	ENOG4105CZX	twitching motility protein
STSP2_01685	ENOG4107QHF	type ii secretion system protein e
STSP2_01686	ENOG4105D7Q	type ii secretion system
STSP2_01688	ENOG4108VAU	general secretion pathway protein G
STSP2_01691	ENOG4105KHS	type IV fimbrial pilin protein
STSP2_01696	ENOG4105ECY	inositol monophosphatase
STSP2_01701	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
STSP2_01704	ENOG4108IJ2	phosphate acetyltransferase
STSP2_01706	ENOG4105BZJ	Electron transfer flavoprotein
STSP2_01707	ENOG4105C10	Electron transfer flavoprotein
STSP2_01708	ENOG4105C1G	acyl-Coa dehydrogenase
STSP2_01710	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
STSP2_01711	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
STSP2_01717	ENOG4105MJ2	Competence protein
STSP2_01718	ENOG4105CJR	Integral membrane protein (MviN
STSP2_01724	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
STSP2_01725	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
STSP2_01727	ENOG4105CS1	NAD(P)H quinone oxidoreductase
STSP2_01729	ENOG4105CMM	transposase
STSP2_01731	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
STSP2_01732	ENOG4108M0I	Transcriptional regulator
STSP2_01733	ENOG4107R37	Glutamate dehydrogenase
STSP2_01734	ENOG4105D82	Glutamate dehydrogenase
STSP2_01735	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
STSP2_01737	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
STSP2_01740	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
STSP2_01741	ENOG4105C8Q	Methyl-accepting chemotaxis
STSP2_01746	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
STSP2_01750	ENOG4105CRQ	synthase (Component I)
STSP2_01751	ENOG4105DDQ	anthranilate synthase
STSP2_01752	ENOG4108I0Q	anthranilate phosphoribosyltransferase
STSP2_01753	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
STSP2_01754	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
STSP2_01755	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
STSP2_01756	ENOG4105BZ8	glutamate synthase
STSP2_01760	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
STSP2_01769	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
STSP2_01773	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
STSP2_01778	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
STSP2_01779	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
STSP2_01780	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
STSP2_01783	ENOG4105DM4	PTS System
STSP2_01785	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
STSP2_01788	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
STSP2_01790	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
STSP2_01791	ENOG4105D2H	Uronic isomerase
STSP2_01792	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
STSP2_01796	ENOG4105DMW	Dehydrogenase reductase
STSP2_01797	ENOG4105CTQ	phosphohexokinase
STSP2_01798	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
STSP2_01799	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
STSP2_01801	ENOG4105DM4	PTS System
STSP2_01803	ENOG4105CY3	ABC transporter, permease
STSP2_01806	ENOG4105VYW	UPF0251 protein
STSP2_01809	ENOG4105D1F	ATP-binding protein
STSP2_01814	ENOG4105K64	Glycosyl transferase, family 2
STSP2_01815	ENOG4105BZ1	(ABC) transporter
STSP2_01817	ENOG4105C6K	Malic enzyme
STSP2_01818	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
STSP2_01820	ENOG4105EDR	glucose galactose transporter
STSP2_01825	ENOG4105CMM	transposase
STSP2_01831	ENOG4105CFH	Aspartokinase
STSP2_01838	ENOG4105KQC	Competence protein
STSP2_01841	ENOG4105C3R	Methionine synthase
STSP2_01842	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
STSP2_01846	ENOG4105JXH	GntR family transcriptional regulator
STSP2_01851	ENOG4107SCR	N-acetylneuraminate lyase
STSP2_01853	ENOG4107RJ1	sodium solute
STSP2_01856	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
STSP2_01857	ENOG4105BZU	Histidine kinase
STSP2_01859	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
STSP2_01861	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
STSP2_01863	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
STSP2_01865	ENOG4108KU3	Integrase
STSP2_01875	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
STSP2_01884	ENOG4105FB9	CRISPR-associated protein
STSP2_01888	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
STSP2_01899	ENOG4105W5Q	DNA repair protein (RadC
STSP2_01912	ENOG4105EPC	oxidoreductase
STSP2_01913	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
STSP2_01919	ENOG4106855	Competence protein
STSP2_01926	ENOG4105C8I	hydrolase, family 38
STSP2_01931	ENOG4106855	Competence protein
STSP2_01933	ENOG4105ETE	Transcriptional regulator (LacI family
STSP2_01934	ENOG4105ETE	Transcriptional regulator (LacI family
STSP2_01936	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
STSP2_01949	ENOG4105EKQ	RNA-directed DNA polymerase
STSP2_01951	ENOG4108KU3	Integrase
STSP2_01970	ENOG4109015	Biopolymer transport protein exbD tolR
STSP2_01983	ENOG4105EKQ	RNA-directed DNA polymerase
STSP2_01984	ENOG4105D5G	Transposase
STSP2_01986	ENOG4105CNT	hydrolase family 2
STSP2_01993	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
STSP2_01995	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
STSP2_02006	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
STSP2_02009	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
STSP2_02010	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
STSP2_02011	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
STSP2_02012	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
STSP2_02013	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
STSP2_02014	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
STSP2_02015	ENOG4105ENH	Sulfatase
STSP2_02016	ENOG41061MV	Arylsulfatase
STSP2_02017	ENOG4108Z1Z	gCN5-related N-acetyltransferase
STSP2_02021	ENOG4105CMM	transposase
STSP2_02024	ENOG4105CMM	transposase
STSP2_02032	ENOG4105DA5	(ABC) transporter
STSP2_02037	ENOG4107QYV	phosphohexose isomerase
STSP2_02039	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
STSP2_02043	ENOG4105VIE	preprotein translocase, subunit YajC
STSP2_02044	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
STSP2_02045	ENOG4105JFG	SpoIID LytB domain protein
STSP2_02046	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
STSP2_02048	ENOG4105CRE	cytochrome C
STSP2_02049	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
STSP2_02052	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
STSP2_02053	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
STSP2_02054	ENOG4105KZ7	phosphocarrier protein hpr
STSP2_02055	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
STSP2_02057	ENOG4105C03	ribonuclease
STSP2_02058	ENOG4105C2X	Arabinose 5-phosphate isomerase
STSP2_02059	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
STSP2_02068	ENOG4105CH7	arginosuccinase
STSP2_02069	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
STSP2_02070	ENOG4105K8N	protein family UPF0079, ATPase
STSP2_02071	ENOG4108VAU	general secretion pathway protein G
STSP2_02082	ENOG4105GVR	general secretion pathway protein D
STSP2_02084	ENOG4105BZU	Histidine kinase
STSP2_02085	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
STSP2_02086	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
STSP2_02087	ENOG41084GC	stage II sporulation protein
STSP2_02088	ENOG4107QHF	type ii secretion system protein e
STSP2_02089	ENOG4105D7Q	type ii secretion system
STSP2_02090	ENOG4105CK5	oxidoreductase
STSP2_02091	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
STSP2_02092	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
STSP2_02093	ENOG4105VEQ	Cold shock protein
STSP2_02095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
STSP2_02096	ENOG4105CPC	Aldo Keto reductase
STSP2_02097	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
STSP2_02098	ENOG4105CPQ	Dehydrogenase
STSP2_02106	ENOG4105C87	Aminotransferase class I and II
STSP2_02107	ENOG4107QNK	)-transporter
STSP2_02114	ENOG4107R3K	hydrolase
STSP2_02115	ENOG4108HKT	sucrose-6-phosphate hydrolase
STSP2_02116	ENOG4105FE9	pseudouridine synthase
STSP2_02118	ENOG410851C	50S ribosomal protein l28
STSP2_02119	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
STSP2_02120	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
STSP2_02121	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
STSP2_02123	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
STSP2_02125	ENOG4107543	(lipo)polysaccharide
STSP2_02126	ENOG4105XA0	heptosyltransferase ii
STSP2_02127	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
STSP2_02128	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
STSP2_02129	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
STSP2_02132	ENOG4105C1V	Peptidase, M16
STSP2_02133	ENOG4105C1V	Peptidase, M16
STSP2_02134	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
STSP2_02135	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
STSP2_02138	ENOG4107S0N	DJ-1 family
STSP2_02146	ENOG4107Y03	Nitroreductase
STSP2_02148	ENOG4105EX0	alpha-galactosidase
STSP2_02149	ENOG4108EKI	Dehydrogenase
STSP2_02150	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
STSP2_02151	ENOG4105GKE	subunit e
STSP2_02156	ENOG4105C4X	radical SAM domain protein
STSP2_02157	ENOG4105C31	Tryptophanyl-tRNA synthetase
STSP2_02159	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
STSP2_02160	ENOG4105K63	Thioredoxin
STSP2_02161	ENOG4105C9M	aspartyl-trna synthetase
STSP2_02162	ENOG4105BZU	Histidine kinase
STSP2_02164	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
STSP2_02166	ENOG4105CZX	twitching motility protein
STSP2_02171	ENOG4105BZU	Histidine kinase
STSP2_02172	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
STSP2_02174	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
STSP2_02175	ENOG4105DKQ	ROK family
STSP2_02176	ENOG4105BZJ	Electron transfer flavoprotein
STSP2_02177	ENOG4105C10	Electron transfer flavoprotein
STSP2_02178	ENOG4105CQB	FAD linked oxidase domain protein
STSP2_02179	ENOG4105CPQ	Dehydrogenase
STSP2_02180	ENOG4105C6K	Malic enzyme
STSP2_02182	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
STSP2_02183	ENOG4105CKK	Glycosyl transferase, family 2
STSP2_02185	ENOG4105CHM	Aminotransferase
STSP2_02186	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
STSP2_02187	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
STSP2_02188	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
STSP2_02189	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
STSP2_02190	ENOG4105CHM	Aminotransferase
STSP2_02191	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
STSP2_02192	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
STSP2_02193	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
STSP2_02195	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
STSP2_02196	ENOG4108YZG	isomerase
STSP2_02197	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
STSP2_02214	ENOG4105ESP	cell wall surface anchor family protein
STSP2_02220	ENOG4108Z6B	deaminase
STSP2_02226	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
STSP2_02228	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
STSP2_02232	ENOG4107QNK	)-transporter
STSP2_02234	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
STSP2_02235	ENOG4105C22	threonyL-tRNA synthetase
STSP2_02236	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
STSP2_02237	ENOG4105VJV	50s ribosomal protein L35
STSP2_02239	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
STSP2_02243	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
STSP2_02245	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
STSP2_02247	ENOG41063JG	Transcriptional regulator
STSP2_02248	ENOG4105VZ9	UPF0235 protein
STSP2_02250	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
STSP2_02251	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
STSP2_02252	ENOG4105C8M	UPF0272 protein
STSP2_02261	ENOG4106855	Competence protein
STSP2_02265	ENOG4105T16	Transcriptional regulator (AraC family)
STSP2_02266	ENOG4105EPC	oxidoreductase
STSP2_02277	ENOG4105T16	Transcriptional regulator (AraC family)
STSP2_02285	ENOG4105ENH	Sulfatase
STSP2_02290	ENOG4105CMM	transposase
STSP2_02297	ENOG4105CNT	hydrolase family 2
STSP2_02299	ENOG4105CNT	hydrolase family 2
STSP2_02300	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
STSP2_02306	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
STSP2_02307	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
STSP2_02308	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
STSP2_02318	ENOG4105CT4	transporter
STSP2_02319	ENOG4108VAU	general secretion pathway protein G
STSP2_02324	ENOG4105T16	Transcriptional regulator (AraC family)
STSP2_02325	ENOG4105CMG	Carbohydrate kinase
STSP2_02326	ENOG4107QNK	)-transporter
STSP2_02330	ENOG4108JU6	CBS domain protein
STSP2_02334	ENOG4105BZU	Histidine kinase
STSP2_02339	ENOG4105DI5	UPF0365 protein
STSP2_02341	ENOG4105F7J	membrane-bound serine protease
STSP2_02342	ENOG4105CHM	Aminotransferase
STSP2_02345	ENOG41084BZ	50S ribosomal protein L32
STSP2_02346	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
STSP2_02347	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
STSP2_02348	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
STSP2_02349	ENOG4105CHR	reductase
STSP2_02350	ENOG41083PU	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
STSP2_02376	ENOG4108CIP	transcriptional regulator
STSP2_02377	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
STSP2_02385	ENOG4108C33	Resolvase
STSP2_02393	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
STSP2_02401	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
STSP2_02411	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
STSP2_02414	ENOG4105DKQ	ROK family
STSP2_02415	ENOG4105CMR	udp-glucose 4-epimerase
STSP2_02417	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
STSP2_02423	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
STSP2_02425	ENOG4105CY0	Metallo-Beta-Lactamase
STSP2_02426	ENOG4105BZU	Histidine kinase
STSP2_02432	ENOG4108YZA	Nitrogen regulatory protein pii
STSP2_02437	ENOG4108BAS	reductase
STSP2_02438	ENOG4105CPQ	Dehydrogenase
STSP2_02440	ENOG4105DET	Rhamnulokinase
STSP2_02442	ENOG4105CPP	Dehydrogenase, E1 component
STSP2_02454	ENOG4105NWF	RbsD or FucU transport
STSP2_02456	ENOG4105CKK	Glycosyl transferase, family 2
STSP2_02463	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
STSP2_02470	ENOG4105D9R	oxidoreductase
STSP2_02472	ENOG4105CUZ	uba thif-type nad fad binding protein
STSP2_02479	ENOG4105DIN	metallophosphoesterase
STSP2_02481	ENOG4105Q36	FHA domain containing protein
STSP2_02484	ENOG4105EI2	Pseudouridine synthase
STSP2_02487	ENOG4105D6E	homoserine dehydrogenase
STSP2_02488	ENOG4105E3H	phosphoglycerate mutase
STSP2_02492	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
STSP2_02500	ENOG41082AN	stage II sporulation protein
STSP2_02501	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
STSP2_02508	ENOG4105ECY	inositol monophosphatase
STSP2_02516	ENOG4105C8J	)-transporter
STSP2_02518	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
STSP2_02519	ENOG4108V0P	LemA family
STSP2_02522	ENOG4105D0M	Protease HtpX homolog
STSP2_02524	ENOG4105CJW	magnesium transporter
STSP2_02525	ENOG4105CZX	twitching motility protein
STSP2_02526	ENOG4107QHF	type ii secretion system protein e
STSP2_02533	ENOG4105D9P	serine threonine protein kinase
STSP2_02534	ENOG4108IG5	Transcriptional regulator
STSP2_02535	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
STSP2_02536	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
STSP2_02537	ENOG4105C4K	Nad synthetase
STSP2_02539	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
STSP2_02547	ENOG4105DG6	mannose-6-phosphate isomerase
STSP2_02550	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
STSP2_02551	ENOG4105CNT	hydrolase family 2
STSP2_02555	ENOG4105CE1	Ferrous iron transport protein b
STSP2_02558	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
STSP2_02561	ENOG4108JQ7	(ABC) transporter
STSP2_02562	ENOG4105C3U	ABC transporter
STSP2_02563	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
STSP2_02565	ENOG4108J59	Extracellular solute-binding protein, family 5
STSP2_02566	ENOG4105DEF	Extracellular solute-binding protein, family 5
STSP2_02568	ENOG4105DEF	Extracellular solute-binding protein, family 5
STSP2_02571	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
STSP2_02572	ENOG4105DC1	bifunctional purine biosynthesis protein purh
STSP2_02576	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
STSP2_02577	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
STSP2_02578	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
STSP2_02579	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
STSP2_02580	ENOG4108KJP	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
STSP2_02581	ENOG410842R	atp synthase
STSP2_02582	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
STSP2_02586	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
STSP2_02590	ENOG4105EMN	RNA polymerase sigma factor
STSP2_02593	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
STSP2_02594	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
STSP2_02597	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
STSP2_02601	ENOG4105BZM	domain protein
STSP2_02602	ENOG4105DZ0	fad dependent oxidoreductase
STSP2_02603	ENOG4105C3F	Signal peptidase i
STSP2_02604	ENOG4105C3F	Signal peptidase i
STSP2_02605	ENOG4105K70	DNA-binding protein
STSP2_02606	ENOG4105VEQ	Cold shock protein
STSP2_02608	ENOG4105BZ8	glutamate synthase
STSP2_02609	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
STSP2_02610	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
STSP2_02611	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
STSP2_02612	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
STSP2_02616	ENOG4105CBG	Sulfatase
STSP2_02617	ENOG4105EX0	alpha-galactosidase
STSP2_02618	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
STSP2_02619	ENOG4105BZS	acriflavin resistance protein
STSP2_02621	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
STSP2_02622	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
STSP2_02623	ENOG4105BZU	Histidine kinase
STSP2_02625	ENOG4105WH1	Two component transcriptional regulator luxr family
STSP2_02629	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
STSP2_02630	ENOG4105CMR	udp-glucose 4-epimerase
STSP2_02633	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
STSP2_02638	ENOG4105K64	Glycosyl transferase, family 2
STSP2_02643	ENOG4107QJZ	Glycosyl transferase, family 2
STSP2_02644	ENOG4105DZS	Phenylacetate-CoA ligase
STSP2_02647	ENOG41089GP	Oxidoreductase domain protein
STSP2_02652	ENOG4107YJ4	chain length determinant protein
STSP2_02653	ENOG4105D3Q	Sugar transferase
STSP2_02655	ENOG4105WH1	Two component transcriptional regulator luxr family
STSP2_02666	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
STSP2_02673	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
STSP2_02675	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
STSP2_02676	ENOG4105C7Z	Conserved Protein
STSP2_02679	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
STSP2_02680	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
STSP2_02681	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
STSP2_02682	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
STSP2_02683	ENOG4105VCQ	rubredoxin
STSP2_02686	ENOG4105MAX	Superoxide reductase
STSP2_02687	ENOG4105CNW	domain protein
STSP2_02688	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
STSP2_02689	ENOG4108RAC	Rubrerythrin
STSP2_02690	ENOG41090R7	Ferric uptake
STSP2_02699	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
STSP2_02701	ENOG4105C5H	ABC transporter
STSP2_02702	ENOG4105CKU	formyltetrahydrofolate synthetase
STSP2_02704	ENOG4105WZ4	isomerase
STSP2_02707	ENOG4105EPC	oxidoreductase
STSP2_02708	ENOG4108R6W	Transcriptional regulator, ARAC family
STSP2_02709	ENOG4105CNT	hydrolase family 2
STSP2_02710	ENOG4105ESP	cell wall surface anchor family protein
STSP2_02711	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
STSP2_02712	ENOG4105BZU	Histidine kinase
STSP2_02714	ENOG4105CVA	phosphate
STSP2_02715	ENOG4105C8U	phosphate abc transporter
STSP2_02716	ENOG4105E2Z	phosphate ABC transporter (Permease
STSP2_02717	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
STSP2_02719	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
STSP2_02724	ENOG4107VJY	DNA polymerase
STSP2_02727	ENOG410827H	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
STSP2_02732	ENOG4105CMM	transposase
STSP2_02733	ENOG4105BZU	Histidine kinase
STSP2_02736	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
STSP2_02739	ENOG4105NAA	Cytochrome C oxidase, subunit II
STSP2_02745	ENOG4107543	(lipo)polysaccharide
STSP2_02746	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
STSP2_02748	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
STSP2_02749	ENOG4105E2D	ec 3.2.1.52
STSP2_02752	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
STSP2_02756	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
STSP2_02757	ENOG4105EQI	Metal Dependent Phosphohydrolase
STSP2_02758	ENOG4108JUA	Transcriptional regulator
STSP2_02762	ENOG4105D7Q	type ii secretion system
STSP2_02763	ENOG4105CZX	twitching motility protein
STSP2_02764	ENOG4107QHF	type ii secretion system protein e
STSP2_02769	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
STSP2_02770	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
STSP2_02773	ENOG4107QHF	type ii secretion system protein e
STSP2_02774	ENOG4105CZX	twitching motility protein
STSP2_02783	ENOG4107QJE	Chromosome Partitioning Protein
STSP2_02786	ENOG4105C3J	Cysteine desulfurase
STSP2_02789	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
STSP2_02790	ENOG4105D7W	serine acetyltransferase
STSP2_02792	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
STSP2_02795	ENOG4107R5Z	Oxidoreductase domain protein
STSP2_02796	ENOG4105J5G	Transferase hexapeptide repeat containing protein
STSP2_02803	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
STSP2_02808	ENOG4107R0V	Pyruvate dehydrogenase
STSP2_02813	ENOG4105E0M	Sulfatase
STSP2_02814	ENOG41075H3	AraC family transcriptional regulator
STSP2_02815	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
STSP2_02816	ENOG4105DZP	Membrane-associated zinc metalloprotease
STSP2_02816	ENOG4105DZP	Membrane-associated zinc metalloprotease
STSP2_02817	ENOG4105K64	Glycosyl transferase, family 2
STSP2_02818	ENOG4105K64	Glycosyl transferase, family 2
STSP2_02819	ENOG4105K64	Glycosyl transferase, family 2
STSP2_02823	ENOG4107T8Q	Glycosyl transferase (Group 1
STSP2_02824	ENOG4108KQJ	Type 11 methyltransferase
STSP2_02826	ENOG4105CKK	Glycosyl transferase, family 2
STSP2_02830	ENOG4107QHF	type ii secretion system protein e
STSP2_02831	ENOG4105D7Q	type ii secretion system
STSP2_02832	ENOG4108VAU	general secretion pathway protein G
STSP2_02840	ENOG4105K4W	Could be involved in septation (By similarity)
STSP2_02841	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
STSP2_02845	ENOG4108Z03	MAF-like protein
STSP2_02847	ENOG4105EMN	RNA polymerase sigma factor
STSP2_02849	ENOG4105CUY	Mechanosensitive ion channel
STSP2_02850	ENOG4105CN9	Peptidase m42 family protein
STSP2_02852	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
STSP2_02859	ENOG4105CJ1	ABC, transporter
STSP2_02861	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
STSP2_02862	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
STSP2_02864	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
STSP2_02867	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
STSP2_02868	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
STSP2_02871	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
STSP2_02872	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
STSP2_02873	ENOG4105F0I	Aminotransferase
STSP2_02874	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
STSP2_02877	ENOG41061MV	Arylsulfatase
STSP2_02888	ENOG4105BZU	Histidine kinase
STSP2_02889	ENOG4105BZU	Histidine kinase
STSP2_02890	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
STSP2_02898	ENOG4105CGK	Exodeoxyribonuclease III
STSP2_02899	ENOG4105CJ1	ABC, transporter
STSP2_02903	ENOG4105BZ1	(ABC) transporter
STSP2_02905	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
STSP2_02906	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
STSP2_02907	ENOG4105C19	ABC transporter
STSP2_02908	ENOG4107RBB	ABC transporter, permease
STSP2_02911	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
STSP2_02912	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
STSP2_02913	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
STSP2_02915	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
STSP2_02917	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
STSP2_02918	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
STSP2_02921	ENOG4105EHG	Permease protein
STSP2_02922	ENOG4105E0A	ABC, transporter
STSP2_02923	ENOG4105SCY	DNAK suppressor
STSP2_02924	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
STSP2_02928	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
STSP2_02929	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
STSP2_02930	ENOG4105D48	metallophosphoesterase
STSP2_02931	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
STSP2_02937	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
STSP2_02938	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
STSP2_02942	ENOG4105EMN	RNA polymerase sigma factor
STSP2_02944	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
STSP2_02952	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
STSP2_02953	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
STSP2_02955	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
STSP2_02963	ENOG4105E4G	Type IV pilus
STSP2_02969	ENOG4108VAU	general secretion pathway protein G
STSP2_02971	ENOG4107QHF	type ii secretion system protein e
STSP2_02972	ENOG4105BZU	Histidine kinase
STSP2_02976	ENOG4106855	Competence protein
STSP2_02985	ENOG4105CMM	transposase
STSP2_02988	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
STSP2_02991	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
STSP2_02996	ENOG41061MV	Arylsulfatase
STSP2_02998	ENOG4105CBG	Sulfatase
STSP2_03002	ENOG4105C8I	hydrolase, family 38
STSP2_03007	ENOG4105DDI	hemolysin-type calcium-binding region
STSP2_03014	ENOG4105CBG	Sulfatase
STSP2_03015	ENOG4105CBG	Sulfatase
STSP2_03017	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
STSP2_03020	ENOG4105CMM	transposase
STSP2_03023	ENOG4105K59	histidine triad (HIT) protein
STSP2_03024	ENOG4108ZT0	50S ribosomal protein l17
STSP2_03025	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
STSP2_03026	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
STSP2_03027	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
STSP2_03028	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
STSP2_03029	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
STSP2_03030	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
STSP2_03031	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
STSP2_03032	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
STSP2_03033	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
STSP2_03034	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
STSP2_03035	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
STSP2_03037	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
STSP2_03038	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
STSP2_03039	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
STSP2_03040	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
STSP2_03041	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
STSP2_03042	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
STSP2_03043	ENOG41082SA	50s ribosomal protein l29
STSP2_03044	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
STSP2_03045	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
STSP2_03046	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
STSP2_03047	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
STSP2_03048	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
STSP2_03049	ENOG410855W	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
STSP2_03050	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
STSP2_03051	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
STSP2_03052	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
STSP2_03053	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
STSP2_03054	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
STSP2_03055	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
STSP2_03056	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
STSP2_03057	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
STSP2_03058	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
STSP2_03059	ENOG4108VZM	50s ribosomal protein L10
STSP2_03060	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
STSP2_03061	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
STSP2_03066	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
STSP2_03072	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
STSP2_03076	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
STSP2_03082	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
STSP2_03083	ENOG4105VFF	UPF0102 protein
STSP2_03084	ENOG4105F8V	Hydrolase, tatD family
STSP2_03086	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
STSP2_03087	ENOG4105C5S	asparaginyl-tRNA synthetase
STSP2_03088	ENOG4108R66	Conserved Protein
STSP2_03090	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
STSP2_03093	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
STSP2_03094	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
STSP2_03096	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
STSP2_03097	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
STSP2_03105	ENOG4105C5R	Aminotransferase
STSP2_03108	ENOG4105BZU	Histidine kinase
STSP2_03109	ENOG4105BZU	Histidine kinase
STSP2_03111	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
STSP2_03113	ENOG4105BZU	Histidine kinase
STSP2_03116	ENOG4105E2D	ec 3.2.1.52
STSP2_03117	ENOG4105CHM	Aminotransferase
STSP2_03118	ENOG4105BZU	Histidine kinase
STSP2_03125	ENOG4105ENH	Sulfatase
STSP2_03147	ENOG4105CNU	cell division protein FtsK
STSP2_03190	ENOG4105EIE	fructose-bisphosphate aldolase
STSP2_03194	ENOG4105CHR	reductase
STSP2_03195	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
STSP2_03197	ENOG4107258	Transcriptional regulator
STSP2_03198	ENOG4105C0H	protease
STSP2_03201	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
STSP2_03207	ENOG4107QRP	cobalamin biosynthesis protein CobW
STSP2_03210	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
STSP2_03211	ENOG4107XM9	(LipO)protein
STSP2_03212	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
STSP2_03214	ENOG4105CTP	PilT protein domain protein
STSP2_03215	ENOG4105D64	Mechanosensitive ion channel
STSP2_03222	ENOG41069ER	domain protein
STSP2_03225	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
STSP2_03234	ENOG4105T16	Transcriptional regulator (AraC family)
STSP2_03235	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
STSP2_03245	ENOG4105CMM	transposase
STSP2_03246	ENOG4108DT4	serine threonine protein kinase
STSP2_03252	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
STSP2_03254	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
STSP2_03264	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
STSP2_03277	ENOG4105CFI	type iii restriction protein res subunit
STSP2_03287	ENOG4105DZR	Type I site-specific deoxyribonuclease
STSP2_03301	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
STSP2_03303	ENOG4105BZU	Histidine kinase
STSP2_03304	ENOG4105BZU	Histidine kinase
STSP2_03306	ENOG4108V1U	phospholipid-binding protein
STSP2_03309	ENOG4107X8Y	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
STSP2_03310	ENOG4108SET	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
STSP2_03311	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
STSP2_03314	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
STSP2_03320	ENOG4107RF6	penicillin-binding protein
STSP2_03321	ENOG4105CJN	penicillin-binding protein
STSP2_03324	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
STSP2_03326	ENOG4108V6E	Cell division protein mraZ
STSP2_03330	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
STSP2_03336	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
STSP2_03337	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
STSP2_03338	ENOG4105DCG	PHP domain protein
STSP2_03343	ENOG4105BZF	Glycosyl transferase (Group 1
STSP2_03345	ENOG4108Z0Z	intracellular protease Pfpi family
STSP2_03349	ENOG4105C5X	domain protein
STSP2_03354	ENOG4107RM6	sulfurtransferase
STSP2_03357	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
STSP2_03358	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
STSP2_03359	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
STSP2_03360	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
STSP2_03361	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
STSP2_03364	ENOG4105CFG	Acts as a chaperone (By similarity)
STSP2_03366	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
STSP2_03369	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
STSP2_03370	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
STSP2_03371	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
STSP2_03384	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
STSP2_03385	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
STSP2_03386	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
STSP2_03387	ENOG4105CE9	30S ribosomal protein S2
STSP2_03392	ENOG4105D8X	mechanosensitive ion channel
STSP2_03393	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
STSP2_03394	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
STSP2_03398	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
STSP2_03401	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
STSP2_03402	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
STSP2_03406	ENOG4105CFP	Peptidase U32
STSP2_03407	ENOG4108RCM	Nitroreductase
STSP2_03409	ENOG4105CPF	Cell wall formation (By similarity)
STSP2_03410	ENOG4105D4A	Cell wall formation (By similarity)
STSP2_03411	ENOG4105DFU	Cell wall formation (By similarity)
STSP2_03412	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
STSP2_03414	ENOG4105CAS	nag kinase
STSP2_03415	ENOG4105C8Y	Acetylornithine aminotransferase
STSP2_03416	ENOG4105DBV	ornithine carbamoyltransferase
STSP2_03417	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
STSP2_03421	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
STSP2_03428	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
STSP2_03429	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
STSP2_03430	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
STSP2_03432	ENOG4105CK7	Sodium proline symporter
STSP2_03438	ENOG4105CK5	oxidoreductase
STSP2_03439	ENOG4105C5I	Dehydrogenase
STSP2_03442	ENOG4105WMR	Protein CrcB homolog
STSP2_03443	ENOG4105KJJ	Uncharacterized ACR, COG1993
STSP2_03444	ENOG4107RAN	Peptidase, M16
STSP2_03446	ENOG4105CD3	dihydroorotase
STSP2_03447	ENOG4105CXT	aspartate transcarbamylase
STSP2_03448	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
STSP2_03451	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
STSP2_03453	ENOG41072GX	Peptidase M22 Glycoprotease
STSP2_03454	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
STSP2_03455	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
STSP2_03456	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
STSP2_03457	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
STSP2_03458	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
STSP2_03461	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
STSP2_03468	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
STSP2_03469	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
STSP2_03470	ENOG4105EAH	synthase
STSP2_03471	ENOG4105CM2	brancheD-chain amino acid aminotransferase
STSP2_03472	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
STSP2_03475	ENOG4105CRK	lysyL-tRNA synthetase
STSP2_03476	ENOG4105CN1	protease
STSP2_03477	ENOG4105D2N	Aldolase
STSP2_03482	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
STSP2_03483	ENOG4105BZP	glycoside hydrolase 15-related
STSP2_03485	ENOG4106855	Competence protein
STSP2_03486	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
STSP2_03487	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
STSP2_03489	ENOG4105C6N	Formate acetyltransferase
STSP2_03490	ENOG4105F1A	Pyruvate formate-lyase
STSP2_03493	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
STSP2_03494	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
STSP2_03495	ENOG4105CTQ	phosphohexokinase
STSP2_03497	ENOG4105DSF	transport protein
STSP2_03508	ENOG4105F8V	Hydrolase, tatD family
STSP2_03509	ENOG4105CUZ	uba thif-type nad fad binding protein
STSP2_03512	ENOG4105F2I	Transposase
STSP2_03514	ENOG4105C8Q	Methyl-accepting chemotaxis
STSP2_03518	ENOG4105CPC	Aldo Keto reductase
STSP2_03519	ENOG4107HP6	Transcriptional regulator
STSP2_03521	ENOG4105YB8	TM2 domain containing protein
STSP2_03526	ENOG4105BZU	Histidine kinase
STSP2_03529	ENOG4105CJ2	(LipO)protein
STSP2_03532	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
STSP2_03534	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
STSP2_03535	ENOG4105D3Q	Sugar transferase
STSP2_03536	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
STSP2_03537	ENOG4105ESV	Glycosyl transferase, family 4
STSP2_03541	ENOG4107T8Q	Glycosyl transferase (Group 1
STSP2_03542	ENOG4107TAE	Glycosyl transferase (Group 1
STSP2_03546	ENOG4107QQG	Dehydrogenase
STSP2_03548	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
STSP2_03551	ENOG4106YN8	Prenyltransferase
STSP2_03554	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
STSP2_03558	ENOG4108IUZ	ABC transporter
STSP2_03559	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
STSP2_03560	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)