locus-tag	class	description
STSP2_00004	COG0148	phosphopyruvate hydratase activity
STSP2_00009	COG0688	phosphatidylethanolamine metabolic process
STSP2_00014	COG2201	protein-glutamate methylesterase activity
STSP2_00015	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
STSP2_00017	COG0643	Histidine kinase
STSP2_00017	COG2198	Histidine kinase
STSP2_00019	COG0175	sulfate reduction
STSP2_00021	COG0457	Tetratricopeptide repeat
STSP2_00022	COG1516	flagellar protein fliS
STSP2_00026	COG0745	RESPONSE REGULATOR receiver
STSP2_00031	COG1677	Flagellar hook-basal body complex protein FliE
STSP2_00032	COG1766	The M ring may be actively involved in energy transduction
STSP2_00035	COG1157	protein secretion by the type III secretion system
STSP2_00038	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
STSP2_00039	COG1360	Flagellar Motor Protein
STSP2_00042	COG1338	Plays a role in the flagellum-specific transport system
STSP2_00044	COG1684	flagellar biosynthetic protein fliR
STSP2_00045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
STSP2_00047	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
STSP2_00048	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
STSP2_00048	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
STSP2_00056	COG1706	bacterial-type flagellum-dependent cell motility
STSP2_00058	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
STSP2_00059	COG4786	Flagellar basal body rod
STSP2_00060	COG4786	Flagellar basal body rod
STSP2_00064	COG2204	response regulator
STSP2_00067	COG2204	response regulator
STSP2_00070	COG1776	CheC inhibitor of MCP methylation
STSP2_00070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
STSP2_00071	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
STSP2_00081	COG3119	arylsulfatase activity
STSP2_00082	COG0569	domain protein
STSP2_00084	COG1047	Peptidyl-prolyl cis-trans
STSP2_00085	COG0657	acetylesterase activity
STSP2_00085	COG2755	lipolytic protein G-D-S-L family
STSP2_00086	COG0657	acetylesterase activity
STSP2_00086	COG2755	lipolytic protein G-D-S-L family
STSP2_00088	COG0823	Involved in the tonB-independent uptake of proteins
STSP2_00094	COG2095	MarC family integral membrane protein
STSP2_00095	COG2813	Specifically methylates the guanine in position
STSP2_00095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
STSP2_00100	COG0698	ribose 5-phosphate isomerase
STSP2_00102	COG1475	DNA binding
STSP2_00104	COG1136	(ABC) transporter
STSP2_00114	COG0673	inositol 2-dehydrogenase activity
STSP2_00116	COG0628	permease
STSP2_00119	COG3119	arylsulfatase activity
STSP2_00120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
STSP2_00126	COG3119	arylsulfatase activity
STSP2_00132	COG0730	response to heat
STSP2_00137	COG3335	DDE superfamily endonuclease
STSP2_00139	COG4251	negative regulation of phosphorylation
STSP2_00142	COG1199	ATP-dependent helicase activity
STSP2_00144	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
STSP2_00145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
STSP2_00149	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
STSP2_00155	COG0864	Transcriptional regulator
STSP2_00159	COG0348	domain, Protein
STSP2_00160	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
STSP2_00162	COG3119	arylsulfatase activity
STSP2_00164	COG3525	Glycosyl hydrolase, family 20, catalytic domain
STSP2_00166	COG1192	Involved in chromosome partitioning
STSP2_00173	COG5001	Diguanylate cyclase
STSP2_00173	COG3447	MASE1 domain protein
STSP2_00173	COG5002	protein histidine kinase activity
STSP2_00175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
STSP2_00177	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
STSP2_00190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
STSP2_00193	COG3525	Glycosyl hydrolase, family 20, catalytic domain
STSP2_00203	COG0151	Belongs to the GarS family
STSP2_00210	COG0772	Belongs to the SEDS family
STSP2_00215	COG0443	Heat shock 70 kDa protein
STSP2_00216	COG3869	Catalyzes the specific phosphorylation of arginine residues in
STSP2_00223	COG3177	Filamentation induced by cAMP protein fic
STSP2_00224	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STSP2_00226	COG0235	Class ii aldolase
STSP2_00231	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STSP2_00233	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
STSP2_00234	COG0459	protein refolding
STSP2_00240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STSP2_00241	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
STSP2_00244	COG1278	Cold shock
STSP2_00263	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STSP2_00264	COG4251	negative regulation of phosphorylation
STSP2_00265	COG1454	alcohol dehydrogenase
STSP2_00268	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STSP2_00270	COG3209	COG3209 Rhs family protein
STSP2_00272	COG3209	COG3209 Rhs family protein
STSP2_00275	COG1355	regulation of microtubule-based process
STSP2_00276	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STSP2_00277	COG1192	Involved in chromosome partitioning
STSP2_00278	COG1349	DNA-binding transcription factor activity
STSP2_00284	COG0798	PFAM Bile acid sodium symporter
STSP2_00285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
STSP2_00288	COG1522	sequence-specific DNA binding
STSP2_00291	COG1051	belongs to the nudix hydrolase family
STSP2_00292	COG2081	HI0933 family
STSP2_00295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
STSP2_00297	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
STSP2_00298	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
STSP2_00310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STSP2_00312	COG0569	domain protein
STSP2_00313	COG0561	phosphatase activity
STSP2_00314	COG4251	negative regulation of phosphorylation
STSP2_00315	COG0564	pseudouridine synthase activity
STSP2_00321	COG4191	Histidine kinase
STSP2_00322	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
STSP2_00324	COG3645	SOS response
STSP2_00327	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STSP2_00342	COG1611	Belongs to the LOG family
STSP2_00347	COG1360	Flagellar Motor Protein
STSP2_00356	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STSP2_00357	COG1605	Chorismate mutase
STSP2_00357	COG0077	Prephenate dehydratase
STSP2_00358	COG0149	triose-phosphate isomerase activity
STSP2_00360	COG1561	YicC-like family, N-terminal region
STSP2_00361	COG0194	GDP metabolic process
STSP2_00362	COG1758	RNA polymerase activity
STSP2_00363	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STSP2_00364	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STSP2_00367	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
STSP2_00367	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
STSP2_00368	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
STSP2_00372	COG3345	alpha-galactosidase
STSP2_00385	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
STSP2_00386	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
STSP2_00391	COG2801	Transposase and inactivated derivatives
STSP2_00398	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
STSP2_00399	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STSP2_00400	COG0667	Aldo Keto reductase
STSP2_00403	COG0492	ferredoxin-NADP+ reductase activity
STSP2_00406	COG1475	DNA binding
STSP2_00408	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STSP2_00411	COG2095	MarC family integral membrane protein
STSP2_00413	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
STSP2_00414	COG1074	ATP-dependent DNA helicase activity
STSP2_00415	COG0205	6-phosphofructokinase activity
STSP2_00420	COG0552	protein localization to endoplasmic reticulum
STSP2_00423	COG0071	Belongs to the small heat shock protein (HSP20) family
STSP2_00425	COG3437	response regulator, receiver
STSP2_00425	COG3850	Histidine kinase
STSP2_00425	COG2205	protein histidine kinase activity
STSP2_00425	COG4999	Histidine kinase
STSP2_00427	COG4771	TonB-dependent receptor
STSP2_00432	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
STSP2_00434	COG4969	Belongs to the N-Me-Phe pilin family
STSP2_00435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
STSP2_00437	COG0066	3-isopropylmalate dehydratase activity
STSP2_00438	COG0473	3-isopropylmalate dehydrogenase activity
STSP2_00439	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
STSP2_00444	COG1119	ATPase activity
STSP2_00446	COG3119	arylsulfatase activity
STSP2_00447	COG1160	GTP binding
STSP2_00448	COG1966	Carbon starvation protein
STSP2_00450	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
STSP2_00453	COG0488	(ABC) transporter
STSP2_00456	COG0187	DNA topoisomerase II activity
STSP2_00459	COG4980	gas vesicle protein
STSP2_00459	COG1674	ftsk spoiiie
STSP2_00460	COG1105	Belongs to the carbohydrate kinase PfkB family
STSP2_00461	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STSP2_00462	COG3525	Glycosyl hydrolase, family 20, catalytic domain
STSP2_00468	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
STSP2_00469	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
STSP2_00471	COG0193	aminoacyl-tRNA hydrolase activity
STSP2_00472	COG0360	Binds together with S18 to 16S ribosomal RNA
STSP2_00473	COG0629	single-stranded DNA binding
STSP2_00475	COG0359	binds to the 23S rRNA
STSP2_00476	COG0305	Participates in initiation and elongation during chromosome replication
STSP2_00480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
STSP2_00480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
STSP2_00481	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
STSP2_00484	COG1515	deoxyribonuclease V activity
STSP2_00486	COG3119	arylsulfatase activity
STSP2_00487	COG3119	arylsulfatase activity
STSP2_00494	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
STSP2_00495	COG0028	Belongs to the TPP enzyme family
STSP2_00496	COG0440	acetolactate synthase activity
STSP2_00497	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
STSP2_00500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
STSP2_00503	COG4656	Part of a membrane complex involved in electron transport
STSP2_00504	COG4658	electron transport chain
STSP2_00506	COG4660	Part of a membrane complex involved in electron transport
STSP2_00507	COG4657	Part of a membrane complex involved in electron transport
STSP2_00508	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
STSP2_00523	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
STSP2_00525	COG0268	Binds directly to 16S ribosomal RNA
STSP2_00526	COG0557	exoribonuclease II activity
STSP2_00527	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
STSP2_00528	COG0653	protein targeting
STSP2_00529	COG0735	belongs to the Fur family
STSP2_00537	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
STSP2_00543	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
STSP2_00550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
STSP2_00551	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STSP2_00552	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
STSP2_00553	COG2208	phosphoserine phosphatase activity
STSP2_00554	COG1254	Belongs to the acylphosphatase family
STSP2_00555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
STSP2_00556	COG0673	inositol 2-dehydrogenase activity
STSP2_00558	COG5492	domain, Protein
STSP2_00559	COG0667	Aldo Keto reductase
STSP2_00561	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STSP2_00562	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
STSP2_00563	COG2022	thiamine diphosphate biosynthetic process
STSP2_00566	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
STSP2_00567	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
STSP2_00568	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STSP2_00569	COG0673	inositol 2-dehydrogenase activity
STSP2_00570	COG3622	Belongs to the hyi family
STSP2_00574	COG1012	belongs to the aldehyde dehydrogenase family
STSP2_00579	COG3335	DDE superfamily endonuclease
STSP2_00582	COG1785	Belongs to the alkaline phosphatase family
STSP2_00583	COG3209	COG3209 Rhs family protein
STSP2_00585	COG3209	COG3209 Rhs family protein
STSP2_00589	COG0542	response to heat
STSP2_00591	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
STSP2_00592	COG5012	cobalamin binding
STSP2_00593	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STSP2_00600	COG0405	Gamma-glutamyltransferase
STSP2_00603	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STSP2_00605	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
STSP2_00606	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
STSP2_00607	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STSP2_00608	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STSP2_00615	COG0322	excinuclease ABC activity
STSP2_00627	COG0584	glycerophosphoryl diester phosphodiesterase
STSP2_00632	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
STSP2_00634	COG1278	Cold shock
STSP2_00637	COG1278	Cold shock
STSP2_00638	COG2070	2-Nitropropane dioxygenase
STSP2_00640	COG2015	COG2015, Alkyl sulfatase and related hydrolases
STSP2_00642	COG3335	DDE superfamily endonuclease
STSP2_00647	COG3335	DDE superfamily endonuclease
STSP2_00657	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STSP2_00660	COG0513	Belongs to the DEAD box helicase family
STSP2_00663	COG0840	transmembrane signaling receptor activity
STSP2_00665	COG4251	negative regulation of phosphorylation
STSP2_00666	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
STSP2_00667	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
STSP2_00669	COG0018	arginyl-trna synthetase
STSP2_00670	COG0432	Pfam Uncharacterised protein family UPF0047
STSP2_00674	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STSP2_00675	COG2201	protein-glutamate methylesterase activity
STSP2_00680	COG0439	Biotin carboxylase
STSP2_00681	COG0511	ligase activity, forming carbon-carbon bonds
STSP2_00682	COG0646	methionine synthase
STSP2_00682	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
STSP2_00686	COG0019	diaminopimelate decarboxylase activity
STSP2_00690	COG0309	Hydrogenase expression formation protein (HypE)
STSP2_00691	COG0409	Hydrogenase expression formation protein
STSP2_00693	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
STSP2_00696	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STSP2_00701	COG0542	response to heat
STSP2_00702	COG0406	alpha-ribazole phosphatase activity
STSP2_00702	COG0328	RNA-DNA hybrid ribonuclease activity
STSP2_00704	COG1297	OPT oligopeptide transporter protein
STSP2_00705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STSP2_00709	COG1774	PSP1 C-terminal conserved region
STSP2_00711	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
STSP2_00720	COG0481	GTPase activity
STSP2_00722	COG3119	arylsulfatase activity
STSP2_00723	COG3119	arylsulfatase activity
STSP2_00724	COG0534	Mate efflux family protein
STSP2_00725	COG1929	Belongs to the glycerate kinase type-1 family
STSP2_00726	COG3119	arylsulfatase activity
STSP2_00728	COG3119	arylsulfatase activity
STSP2_00730	COG0598	Magnesium transport protein CorA
STSP2_00732	COG1322	Protein conserved in bacteria
STSP2_00737	COG3119	arylsulfatase activity
STSP2_00738	COG3250	beta-galactosidase activity
STSP2_00748	COG0667	Aldo Keto reductase
STSP2_00750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
STSP2_00750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
STSP2_00752	COG0671	phosphoesterase, PA-phosphatase related
STSP2_00753	COG0110	maltose O-acetyltransferase activity
STSP2_00759	COG0129	dihydroxy-acid dehydratase activity
STSP2_00764	COG0232	Belongs to the dGTPase family. Type 2 subfamily
STSP2_00766	COG1968	undecaprenyl-diphosphatase activity
STSP2_00771	COG0575	Belongs to the CDS family
STSP2_00772	COG1702	phosphate starvation-inducible protein PhoH
STSP2_00773	COG1480	7TM receptor with intracellular HD hydrolase
STSP2_00778	COG2255	four-way junction helicase activity
STSP2_00779	COG0632	four-way junction helicase activity
STSP2_00780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
STSP2_00781	COG0215	cysteine-tRNA ligase activity
STSP2_00782	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
STSP2_00783	COG0131	Imidazoleglycerol-phosphate dehydratase
STSP2_00784	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
STSP2_00785	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
STSP2_00786	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
STSP2_00787	COG0126	phosphoglycerate kinase activity
STSP2_00792	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
STSP2_00796	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
STSP2_00798	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STSP2_00801	COG0772	Belongs to the SEDS family
STSP2_00802	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
STSP2_00805	COG0442	prolyl-tRNA aminoacylation
STSP2_00807	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STSP2_00809	COG3119	arylsulfatase activity
STSP2_00810	COG0217	transcriptional regulatory protein
STSP2_00811	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
STSP2_00814	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
STSP2_00814	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
STSP2_00815	COG0195	Participates in both transcription termination and antitermination
STSP2_00817	COG0284	orotidine-5'-phosphate decarboxylase activity
STSP2_00818	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
STSP2_00824	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
STSP2_00825	COG0539	negative regulation of cytoplasmic translation
STSP2_00825	COG2183	response to ionizing radiation
STSP2_00827	COG4221	oxidoreductase activity
STSP2_00834	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
STSP2_00836	COG3119	arylsulfatase activity
STSP2_00837	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STSP2_00838	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STSP2_00841	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
STSP2_00844	COG0010	Belongs to the arginase family
STSP2_00845	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
STSP2_00846	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STSP2_00855	COG1151	hydroxylamine reductase activity
STSP2_00857	COG1959	2 iron, 2 sulfur cluster binding
STSP2_00862	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STSP2_00863	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STSP2_00865	COG1607	acyl-coa hydrolase
STSP2_00866	COG0211	Belongs to the bacterial ribosomal protein bL27 family
STSP2_00869	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STSP2_00870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STSP2_00871	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STSP2_00877	COG0667	Aldo Keto reductase
STSP2_00882	COG2226	methyltransferase
STSP2_00883	COG0181	hydroxymethylbilane synthase activity
STSP2_00886	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
STSP2_00888	COG0535	radical SAM domain protein
STSP2_00889	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
STSP2_00894	COG0113	porphobilinogen synthase activity
STSP2_00895	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
STSP2_00896	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
STSP2_00901	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
STSP2_00902	COG0254	rRNA binding
STSP2_00906	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STSP2_00907	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
STSP2_00908	COG0302	gtp cyclohydrolase
STSP2_00910	COG2201	protein-glutamate methylesterase activity
STSP2_00912	COG2205	protein histidine kinase activity
STSP2_00912	COG4999	Histidine kinase
STSP2_00912	COG3437	response regulator, receiver
STSP2_00912	COG3850	Histidine kinase
STSP2_00913	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
STSP2_00918	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STSP2_00924	COG2095	MarC family integral membrane protein
STSP2_00925	COG1361	Conserved repeat domain
STSP2_00927	COG0668	transmembrane transport
STSP2_00928	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STSP2_00930	COG4251	negative regulation of phosphorylation
STSP2_00933	COG0446	pyridine nucleotide-disulphide oxidoreductase
STSP2_00935	COG1335	isochorismatase
STSP2_00936	COG1032	radical SAM domain protein
STSP2_00941	COG2226	methyltransferase
STSP2_00972	COG1262	PFAM Formylglycine-generating sulfatase enzyme
STSP2_00977	COG0107	imidazoleglycerol-phosphate synthase activity
STSP2_00994	COG3344	reverse transcriptase
STSP2_00995	COG3328	transposase activity
STSP2_01010	COG0517	IMP dehydrogenase activity
STSP2_01010	COG4175	Glycine betaine
STSP2_01015	COG1408	metallophosphoesterase
STSP2_01021	COG0835	chemotaxis
STSP2_01022	COG0840	transmembrane signaling receptor activity
STSP2_01023	COG0784	Response regulator, receiver
STSP2_01023	COG2205	protein histidine kinase activity
STSP2_01042	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STSP2_01043	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
STSP2_01046	COG0175	sulfate reduction
STSP2_01048	COG1959	2 iron, 2 sulfur cluster binding
STSP2_01059	COG2270	Major facilitator Superfamily
STSP2_01062	COG2801	Transposase and inactivated derivatives
STSP2_01065	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STSP2_01070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
STSP2_01074	COG2255	four-way junction helicase activity
STSP2_01078	COG1061	Type III restriction enzyme res subunit
STSP2_01081	COG1475	DNA binding
STSP2_01082	COG3654	unkown
STSP2_01097	COG1215	transferase activity, transferring glycosyl groups
STSP2_01116	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
STSP2_01121	COG0515	serine threonine protein kinase
STSP2_01126	COG0833	amino acid
STSP2_01130	COG2033	superoxide reductase activity
STSP2_01131	COG1305	Transglutaminase-like
STSP2_01136	COG0657	acetylesterase activity
STSP2_01136	COG2755	lipolytic protein G-D-S-L family
STSP2_01137	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STSP2_01137	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STSP2_01140	COG3119	arylsulfatase activity
STSP2_01141	COG0673	inositol 2-dehydrogenase activity
STSP2_01145	COG3104	oligopeptide transport
STSP2_01149	COG3525	Glycosyl hydrolase, family 20, catalytic domain
STSP2_01150	COG0673	inositol 2-dehydrogenase activity
STSP2_01152	COG3250	beta-galactosidase activity
STSP2_01153	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
STSP2_01155	COG0859	PFAM glycosyl transferase family 9
STSP2_01160	COG1269	ATP hydrolysis coupled proton transport
STSP2_01161	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
STSP2_01166	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
STSP2_01172	COG0534	Mate efflux family protein
STSP2_01200	COG4589	Belongs to the CDS family
STSP2_01201	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STSP2_01202	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
STSP2_01202	COG0574	Belongs to the PEP-utilizing enzyme family
STSP2_01204	COG0220	tRNA (guanine-N7-)-methyltransferase activity
STSP2_01207	COG4974	Belongs to the 'phage' integrase family
STSP2_01210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
STSP2_01234	COG3119	arylsulfatase activity
STSP2_01244	COG3119	arylsulfatase activity
STSP2_01246	COG3119	arylsulfatase activity
STSP2_01263	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
STSP2_01270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
STSP2_01273	COG3335	DDE superfamily endonuclease
STSP2_01294	COG3525	Glycosyl hydrolase, family 20, catalytic domain
STSP2_01298	COG0673	inositol 2-dehydrogenase activity
STSP2_01299	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STSP2_01300	COG0515	serine threonine protein kinase
STSP2_01300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
STSP2_01301	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
STSP2_01304	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STSP2_01308	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STSP2_01309	COG0736	holo-[acyl-carrier-protein] synthase activity
STSP2_01310	COG0445	tRNA wobble uridine modification
STSP2_01312	COG4968	Prepilin-type N-terminal cleavage methylation domain
STSP2_01313	COG4977	sequence-specific DNA binding
STSP2_01313	COG1917	Cupin 2, conserved barrel domain protein
STSP2_01314	COG0366	Alpha amylase catalytic
STSP2_01317	COG1506	peptidase
STSP2_01317	COG0823	Involved in the tonB-independent uptake of proteins
STSP2_01321	COG0204	Acyl-transferase
STSP2_01321	COG0318	PFAM AMP-dependent synthetase and ligase
STSP2_01324	COG2205	protein histidine kinase activity
STSP2_01327	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_01328	COG1459	type II secretion system
STSP2_01343	COG4409	exo-alpha-(2->6)-sialidase activity
STSP2_01346	COG0840	transmembrane signaling receptor activity
STSP2_01347	COG0835	chemotaxis
STSP2_01348	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_01350	COG1595	DNA-templated transcription, initiation
STSP2_01352	COG3119	arylsulfatase activity
STSP2_01353	COG3119	arylsulfatase activity
STSP2_01354	COG3119	arylsulfatase activity
STSP2_01360	COG3901	Regulator of nitric oxide reductase transcription
STSP2_01360	COG0348	domain, Protein
STSP2_01362	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
STSP2_01367	COG0709	Synthesizes selenophosphate from selenide and ATP
STSP2_01368	COG1924	4 iron, 4 sulfur cluster binding
STSP2_01371	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
STSP2_01372	COG2226	methyltransferase
STSP2_01383	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
STSP2_01387	COG0732	type I restriction modification DNA specificity domain
STSP2_01389	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
STSP2_01405	COG0582	viral genome integration into host DNA
STSP2_01407	COG2255	four-way junction helicase activity
STSP2_01423	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
STSP2_01425	COG3119	arylsulfatase activity
STSP2_01427	COG3250	beta-galactosidase activity
STSP2_01430	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
STSP2_01431	COG2205	protein histidine kinase activity
STSP2_01437	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
STSP2_01438	COG0745	RESPONSE REGULATOR receiver
STSP2_01439	COG1160	GTP binding
STSP2_01445	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
STSP2_01450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
STSP2_01456	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
STSP2_01457	COG0495	leucyl-tRNA aminoacylation
STSP2_01459	COG1597	lipid kinase activity
STSP2_01460	COG2877	3-deoxy-8-phosphooctulonate synthase activity
STSP2_01461	COG0731	radical SAM domain protein
STSP2_01461	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
STSP2_01463	COG4974	Belongs to the 'phage' integrase family
STSP2_01464	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
STSP2_01465	COG2195	Cleaves the N-terminal amino acid of tripeptides
STSP2_01467	COG3177	Filamentation induced by cAMP protein fic
STSP2_01470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
STSP2_01474	COG4566	intracellular signal transduction
STSP2_01479	COG0489	protein tyrosine kinase activity
STSP2_01479	COG3206	protein involved in exopolysaccharide biosynthesis
STSP2_01480	COG4464	protein tyrosine phosphatase activity
STSP2_01483	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STSP2_01484	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
STSP2_01487	COG0297	glycogen (starch) synthase activity
STSP2_01492	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
STSP2_01496	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
STSP2_01503	COG0457	Tetratricopeptide repeat
STSP2_01508	COG0352	thiamine-phosphate diphosphorylase activity
STSP2_01510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
STSP2_01512	COG0134	indole-3-glycerol-phosphate synthase activity
STSP2_01513	COG0730	response to heat
STSP2_01514	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
STSP2_01515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
STSP2_01516	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STSP2_01517	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
STSP2_01518	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
STSP2_01519	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
STSP2_01525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
STSP2_01527	COG1611	Belongs to the LOG family
STSP2_01535	COG4284	Utp--glucose-1-phosphate uridylyltransferase
STSP2_01536	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
STSP2_01539	COG0606	chelatase, subunit chli
STSP2_01541	COG0469	pyruvate kinase activity
STSP2_01542	COG3119	arylsulfatase activity
STSP2_01543	COG3335	DDE superfamily endonuclease
STSP2_01546	COG0571	ribonuclease III activity
STSP2_01552	COG2084	Dehydrogenase
STSP2_01557	COG0321	lipoyl(octanoyl) transferase activity
STSP2_01559	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STSP2_01559	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STSP2_01561	COG0556	nucleotide-excision repair
STSP2_01562	COG0828	Belongs to the bacterial ribosomal protein bS21 family
STSP2_01563	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STSP2_01571	COG1191	sigma factor activity
STSP2_01572	COG0455	bacterial-type flagellum organization
STSP2_01575	COG0745	RESPONSE REGULATOR receiver
STSP2_01575	COG3706	GGDEF domain
STSP2_01577	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STSP2_01578	COG1376	ErfK ybiS ycfS ynhG family protein
STSP2_01580	COG0811	peptide transport
STSP2_01582	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
STSP2_01587	COG0674	pyruvate-flavodoxin oxidoreductase activity
STSP2_01600	COG1032	radical SAM domain protein
STSP2_01607	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STSP2_01615	COG1067	ATP-dependent peptidase activity
STSP2_01617	COG0366	Alpha amylase catalytic
STSP2_01619	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
STSP2_01622	COG1640	4-alpha-glucanotransferase
STSP2_01625	COG0714	Associated with various cellular activities
STSP2_01627	COG1131	(ABC) transporter
STSP2_01634	COG3103	Sh3 type 3 domain protein
STSP2_01634	COG0366	Alpha amylase catalytic
STSP2_01646	COG2155	Conserved Protein
STSP2_01654	COG3335	DDE superfamily endonuclease
STSP2_01656	COG0310	cobalt ion transport
STSP2_01657	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
STSP2_01658	COG1122	ATPase activity
STSP2_01663	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
STSP2_01674	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
STSP2_01674	COG1648	precorrin-2 dehydrogenase activity
STSP2_01675	COG3676	manually curated
STSP2_01677	COG3119	arylsulfatase activity
STSP2_01681	COG0012	GTP binding
STSP2_01682	COG1058	Belongs to the CinA family
STSP2_01682	COG1546	Belongs to the CinA family
STSP2_01683	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_01685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_01686	COG1459	type II secretion system
STSP2_01688	COG2165	general secretion pathway protein
STSP2_01691	COG4969	Belongs to the N-Me-Phe pilin family
STSP2_01696	COG0483	inositol monophosphate 1-phosphatase activity
STSP2_01699	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
STSP2_01701	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STSP2_01704	COG0280	phosphate acetyltransferase
STSP2_01706	COG2086	electron transfer activity
STSP2_01707	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
STSP2_01708	COG1960	acyl-CoA dehydrogenase activity
STSP2_01710	COG0358	DNA primase activity
STSP2_01711	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STSP2_01717	COG1040	competence protein
STSP2_01724	COG0322	excinuclease ABC activity
STSP2_01725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
STSP2_01727	COG0655	NAD(P)H dehydrogenase (quinone) activity
STSP2_01729	COG2801	Transposase and inactivated derivatives
STSP2_01732	COG0583	DNA-binding transcription factor activity
STSP2_01733	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STSP2_01734	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STSP2_01735	COG1573	uracil-dna glycosylase
STSP2_01738	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
STSP2_01740	COG0805	protein transport
STSP2_01741	COG0840	transmembrane signaling receptor activity
STSP2_01746	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
STSP2_01750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STSP2_01751	COG0512	Glutamine amidotransferase of anthranilate synthase
STSP2_01753	COG0135	phosphoribosylanthranilate isomerase activity
STSP2_01754	COG0133	tryptophan synthase activity
STSP2_01755	COG0159	tryptophan synthase activity
STSP2_01756	COG0493	'glutamate synthase
STSP2_01760	COG0297	glycogen (starch) synthase activity
STSP2_01769	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
STSP2_01773	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
STSP2_01778	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
STSP2_01779	COG0504	CTP synthase activity
STSP2_01780	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
STSP2_01783	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STSP2_01783	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STSP2_01783	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STSP2_01785	COG0594	ribonuclease P activity
STSP2_01790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
STSP2_01791	COG1904	glucuronate isomerase
STSP2_01792	COG1472	Belongs to the glycosyl hydrolase 3 family
STSP2_01796	COG1028	Short-chain dehydrogenase reductase Sdr
STSP2_01797	COG0205	6-phosphofructokinase activity
STSP2_01799	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
STSP2_01801	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STSP2_01801	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STSP2_01801	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STSP2_01803	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
STSP2_01806	COG1342	Belongs to the UPF0251 family
STSP2_01809	COG0489	protein tyrosine kinase activity
STSP2_01814	COG0463	Glycosyl transferase, family 2
STSP2_01814	COG1216	Glycosyl transferase, family 2
STSP2_01815	COG1132	(ABC) transporter
STSP2_01817	COG0280	phosphate acetyltransferase
STSP2_01817	COG0857	belongs to the CobB CobQ family
STSP2_01818	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
STSP2_01820	COG0738	Major facilitator superfamily
STSP2_01822	COG0616	signal peptide processing
STSP2_01825	COG2801	Transposase and inactivated derivatives
STSP2_01831	COG0527	aspartate kinase activity
STSP2_01832	COG1525	nuclease
STSP2_01838	COG1555	photosystem II stabilization
STSP2_01838	COG1596	polysaccharide export
STSP2_01842	COG1519	Transferase
STSP2_01846	COG2186	Transcriptional regulator
STSP2_01851	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
STSP2_01853	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
STSP2_01857	COG5002	protein histidine kinase activity
STSP2_01861	COG0072	phenylalanine-tRNA ligase activity
STSP2_01863	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
STSP2_01865	COG0582	viral genome integration into host DNA
STSP2_01875	COG2255	four-way junction helicase activity
STSP2_01888	COG1518	maintenance of DNA repeat elements
STSP2_01899	COG2003	Belongs to the UPF0758 family
STSP2_01912	COG0673	inositol 2-dehydrogenase activity
STSP2_01913	COG4977	sequence-specific DNA binding
STSP2_01919	COG4537	Required for transformation and DNA binding
STSP2_01926	COG0383	alpha-mannosidase activity
STSP2_01928	COG2814	Major facilitator Superfamily
STSP2_01931	COG4968	Prepilin-type N-terminal cleavage methylation domain
STSP2_01933	COG1609	Transcriptional regulator
STSP2_01934	COG1609	Transcriptional regulator
STSP2_01936	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
STSP2_01942	COG3385	transposase activity
STSP2_01949	COG3344	reverse transcriptase
STSP2_01951	COG0582	viral genome integration into host DNA
STSP2_01968	COG0811	peptide transport
STSP2_01969	COG0811	peptide transport
STSP2_01970	COG0848	biopolymer transport protein
STSP2_01983	COG3344	reverse transcriptase
STSP2_01984	COG3328	transposase activity
STSP2_01986	COG3250	beta-galactosidase activity
STSP2_01993	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
STSP2_01994	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STSP2_02006	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
STSP2_02009	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
STSP2_02010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STSP2_02011	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STSP2_02012	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
STSP2_02013	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STSP2_02014	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
STSP2_02015	COG3119	arylsulfatase activity
STSP2_02016	COG3119	arylsulfatase activity
STSP2_02017	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
STSP2_02021	COG2801	Transposase and inactivated derivatives
STSP2_02024	COG2801	Transposase and inactivated derivatives
STSP2_02032	COG1131	(ABC) transporter
STSP2_02037	COG0166	Belongs to the GPI family
STSP2_02039	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
STSP2_02040	COG0363	glucosamine-6-phosphate deaminase activity
STSP2_02043	COG1862	Preprotein translocase
STSP2_02044	COG0343	queuine tRNA-ribosyltransferase activity
STSP2_02045	COG2385	sporulation resulting in formation of a cellular spore
STSP2_02046	COG0202	RNA polymerase activity
STSP2_02048	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STSP2_02049	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
STSP2_02052	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
STSP2_02054	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
STSP2_02055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
STSP2_02057	COG1530	ribonuclease E activity
STSP2_02058	COG0517	IMP dehydrogenase activity
STSP2_02058	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
STSP2_02059	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
STSP2_02062	COG3335	DDE superfamily endonuclease
STSP2_02068	COG0165	Argininosuccinate lyase
STSP2_02069	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
STSP2_02084	COG5002	protein histidine kinase activity
STSP2_02087	COG1366	Belongs to the anti-sigma-factor antagonist family
STSP2_02088	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_02089	COG1459	type II secretion system
STSP2_02090	COG0673	inositol 2-dehydrogenase activity
STSP2_02091	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
STSP2_02092	COG1185	polyribonucleotide nucleotidyltransferase activity
STSP2_02093	COG1278	Cold shock
STSP2_02095	COG2204	response regulator
STSP2_02096	COG0667	Aldo Keto reductase
STSP2_02098	COG1063	alcohol dehydrogenase
STSP2_02106	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STSP2_02107	COG2814	Major facilitator Superfamily
STSP2_02107	COG0477	Major facilitator Superfamily
STSP2_02114	COG1621	beta-fructofuranosidase activity
STSP2_02115	COG1621	beta-fructofuranosidase activity
STSP2_02116	COG1187	pseudouridine synthase activity
STSP2_02118	COG0227	Belongs to the bacterial ribosomal protein bL28 family
STSP2_02119	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
STSP2_02120	COG0154	amidase activity
STSP2_02121	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
STSP2_02123	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
STSP2_02125	COG0515	serine threonine protein kinase
STSP2_02126	COG0859	PFAM glycosyl transferase family 9
STSP2_02127	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
STSP2_02128	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
STSP2_02128	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
STSP2_02129	COG1663	tetraacyldisaccharide 4'-kinase activity
STSP2_02132	COG0612	Peptidase, M16
STSP2_02133	COG0612	Peptidase, M16
STSP2_02134	COG1196	nuclear chromosome segregation
STSP2_02135	COG1706	bacterial-type flagellum-dependent cell motility
STSP2_02138	COG0693	protein deglycase activity
STSP2_02146	COG0778	Nitroreductase
STSP2_02148	COG3345	alpha-galactosidase
STSP2_02149	COG1454	alcohol dehydrogenase
STSP2_02149	COG1012	belongs to the aldehyde dehydrogenase family
STSP2_02150	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
STSP2_02151	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
STSP2_02156	COG0641	radical SAM
STSP2_02157	COG0180	Tryptophanyl-tRNA synthetase
STSP2_02159	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
STSP2_02160	COG3118	belongs to the thioredoxin family
STSP2_02164	COG1191	sigma factor activity
STSP2_02171	COG3852	Histidine kinase
STSP2_02172	COG2204	response regulator
STSP2_02174	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
STSP2_02175	COG1940	carbohydrate kinase activity
STSP2_02176	COG2086	electron transfer activity
STSP2_02177	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
STSP2_02178	COG0277	FAD linked oxidase domain protein
STSP2_02179	COG1063	alcohol dehydrogenase
STSP2_02180	COG0281	malic enzyme
STSP2_02182	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
STSP2_02183	COG0463	Glycosyl transferase, family 2
STSP2_02185	COG0436	Aminotransferase
STSP2_02187	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
STSP2_02188	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
STSP2_02189	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
STSP2_02191	COG0745	RESPONSE REGULATOR receiver
STSP2_02192	COG0047	phosphoribosylformylglycinamidine synthase activity
STSP2_02193	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STSP2_02194	COG0287	Prephenate dehydrogenase
STSP2_02195	COG0825	malonyl-CoA metabolic process
STSP2_02196	COG0698	ribose 5-phosphate isomerase
STSP2_02197	COG0009	L-threonylcarbamoyladenylate synthase
STSP2_02214	COG0366	Alpha amylase catalytic
STSP2_02220	COG0590	tRNA wobble adenosine to inosine editing
STSP2_02226	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
STSP2_02228	COG0617	tRNA 3'-terminal CCA addition
STSP2_02231	COG1609	Transcriptional regulator
STSP2_02232	COG0477	Major facilitator Superfamily
STSP2_02232	COG2814	Major facilitator Superfamily
STSP2_02235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
STSP2_02236	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
STSP2_02237	COG0291	Belongs to the bacterial ribosomal protein bL35 family
STSP2_02239	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
STSP2_02243	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
STSP2_02245	COG0482	sulfurtransferase activity
STSP2_02247	COG2912	Transglutaminase-like superfamily
STSP2_02248	COG1872	DUF167
STSP2_02251	COG0543	2 iron, 2 sulfur cluster binding
STSP2_02261	COG4537	Required for transformation and DNA binding
STSP2_02265	COG1609	Transcriptional regulator
STSP2_02265	COG2207	Transcriptional regulator
STSP2_02266	COG0673	inositol 2-dehydrogenase activity
STSP2_02277	COG1609	Transcriptional regulator
STSP2_02277	COG2207	Transcriptional regulator
STSP2_02279	COG3335	DDE superfamily endonuclease
STSP2_02284	COG3335	DDE superfamily endonuclease
STSP2_02285	COG3119	arylsulfatase activity
STSP2_02290	COG2801	Transposase and inactivated derivatives
STSP2_02297	COG3250	beta-galactosidase activity
STSP2_02299	COG3250	beta-galactosidase activity
STSP2_02300	COG3507	Belongs to the glycosyl hydrolase 43 family
STSP2_02308	COG3940	Belongs to the glycosyl hydrolase 43 family
STSP2_02310	COG3335	DDE superfamily endonuclease
STSP2_02318	COG2211	Major facilitator Superfamily
STSP2_02319	COG2165	general secretion pathway protein
STSP2_02324	COG1609	Transcriptional regulator
STSP2_02324	COG2207	Transcriptional regulator
STSP2_02325	COG1070	Carbohydrate kinase
STSP2_02326	COG2814	Major facilitator Superfamily
STSP2_02326	COG0477	Major facilitator Superfamily
STSP2_02329	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
STSP2_02330	COG4536	flavin adenine dinucleotide binding
STSP2_02331	COG1253	flavin adenine dinucleotide binding
STSP2_02334	COG0745	RESPONSE REGULATOR receiver
STSP2_02334	COG3706	GGDEF domain
STSP2_02339	COG4864	UPF0365 protein
STSP2_02341	COG1030	water channel activity
STSP2_02342	COG0436	Aminotransferase
STSP2_02345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
STSP2_02346	COG0416	fatty acid biosynthetic process
STSP2_02347	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
STSP2_02348	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
STSP2_02349	COG1028	Short-chain dehydrogenase reductase Sdr
STSP2_02350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STSP2_02351	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STSP2_02355	COG4191	Histidine kinase
STSP2_02355	COG0784	Response regulator, receiver
STSP2_02376	COG2207	Transcriptional regulator
STSP2_02385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
STSP2_02393	COG4974	Belongs to the 'phage' integrase family
STSP2_02401	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
STSP2_02408	COG1606	tRNA processing
STSP2_02411	COG0205	6-phosphofructokinase activity
STSP2_02414	COG1940	carbohydrate kinase activity
STSP2_02415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STSP2_02417	COG4974	Belongs to the 'phage' integrase family
STSP2_02423	COG0438	transferase activity, transferring glycosyl groups
STSP2_02425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
STSP2_02426	COG4251	negative regulation of phosphorylation
STSP2_02430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STSP2_02431	COG0004	ammonium transporteR
STSP2_02432	COG0347	Belongs to the P(II) protein family
STSP2_02434	COG0067	glutamate synthase
STSP2_02434	COG0070	glutamate synthase
STSP2_02434	COG0069	glutamate synthase activity
STSP2_02437	COG1028	Short-chain dehydrogenase reductase Sdr
STSP2_02438	COG1063	alcohol dehydrogenase
STSP2_02440	COG1070	Carbohydrate kinase
STSP2_02441	COG0508	dehydrogenase complex catalyzes the overall conversion of
STSP2_02442	COG0508	dehydrogenase complex catalyzes the overall conversion of
STSP2_02442	COG0022	dehydrogenase e1 component
STSP2_02443	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STSP2_02454	COG4154	Belongs to the RbsD FucU family
STSP2_02456	COG0463	Glycosyl transferase, family 2
STSP2_02463	COG0673	inositol 2-dehydrogenase activity
STSP2_02470	COG0673	inositol 2-dehydrogenase activity
STSP2_02472	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
STSP2_02479	COG1408	metallophosphoesterase
STSP2_02481	COG1716	ATPase activity
STSP2_02482	COG3335	DDE superfamily endonuclease
STSP2_02484	COG0564	pseudouridine synthase activity
STSP2_02488	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
STSP2_02501	COG1959	2 iron, 2 sulfur cluster binding
STSP2_02503	COG3676	manually curated
STSP2_02506	COG0004	ammonium transporteR
STSP2_02509	COG0483	inositol monophosphate 1-phosphatase activity
STSP2_02516	COG0733	neurotransmitter:sodium symporter activity
STSP2_02519	COG1704	LemA family
STSP2_02522	COG0501	Belongs to the peptidase M48B family
STSP2_02524	COG2239	Acts as a magnesium transporter
STSP2_02526	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_02533	COG2815	serine threonine protein kinase
STSP2_02533	COG0515	serine threonine protein kinase
STSP2_02534	COG1309	transcriptional regulator
STSP2_02535	COG0505	Belongs to the CarA family
STSP2_02537	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
STSP2_02537	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STSP2_02539	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
STSP2_02547	COG1482	cell wall glycoprotein biosynthetic process
STSP2_02550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
STSP2_02551	COG3250	beta-galactosidase activity
STSP2_02555	COG1918	ferrous iron import across plasma membrane
STSP2_02555	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
STSP2_02558	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STSP2_02561	COG4608	Belongs to the ABC transporter superfamily
STSP2_02562	COG0444	Belongs to the ABC transporter superfamily
STSP2_02563	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STSP2_02564	COG0601	transmembrane transport
STSP2_02565	COG4166	transmembrane transport
STSP2_02566	COG0747	negative chemotaxis
STSP2_02568	COG0747	negative chemotaxis
STSP2_02571	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
STSP2_02576	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
STSP2_02577	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
STSP2_02578	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
STSP2_02579	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
STSP2_02580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
STSP2_02581	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
STSP2_02582	COG0356	it plays a direct role in the translocation of protons across the membrane
STSP2_02586	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
STSP2_02590	COG1595	DNA-templated transcription, initiation
STSP2_02593	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
STSP2_02594	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
STSP2_02597	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
STSP2_02601	COG2183	response to ionizing radiation
STSP2_02602	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
STSP2_02603	COG0681	Belongs to the peptidase S26 family
STSP2_02605	COG0776	regulation of translation
STSP2_02606	COG1278	Cold shock
STSP2_02608	COG0493	'glutamate synthase
STSP2_02608	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
STSP2_02609	COG0543	2 iron, 2 sulfur cluster binding
STSP2_02610	COG1136	(ABC) transporter
STSP2_02610	COG0577	efflux transmembrane transporter activity
STSP2_02611	COG1136	(ABC) transporter
STSP2_02612	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STSP2_02616	COG3119	arylsulfatase activity
STSP2_02617	COG3345	alpha-galactosidase
STSP2_02619	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
STSP2_02620	COG1091	dTDP-4-dehydrorhamnose reductase activity
STSP2_02621	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
STSP2_02622	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
STSP2_02623	COG4585	Histidine kinase
STSP2_02625	COG2197	response regulator
STSP2_02627	COG0784	Response regulator, receiver
STSP2_02629	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
STSP2_02630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STSP2_02633	COG0500	methyltransferase
STSP2_02638	COG1215	transferase activity, transferring glycosyl groups
STSP2_02644	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
STSP2_02647	COG0673	inositol 2-dehydrogenase activity
STSP2_02652	COG0489	protein tyrosine kinase activity
STSP2_02653	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
STSP2_02655	COG2197	response regulator
STSP2_02666	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
STSP2_02673	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STSP2_02675	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
STSP2_02676	COG1331	Highly conserved protein containing a thioredoxin domain
STSP2_02679	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
STSP2_02680	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
STSP2_02683	COG1773	rubredoxin
STSP2_02686	COG2033	superoxide reductase activity
STSP2_02687	COG0426	domain, Protein
STSP2_02688	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
STSP2_02689	COG1592	Rubrerythrin
STSP2_02694	COG0848	biopolymer transport protein
STSP2_02696	COG0811	peptide transport
STSP2_02699	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
STSP2_02707	COG0673	inositol 2-dehydrogenase activity
STSP2_02708	COG2207	Transcriptional regulator
STSP2_02709	COG3250	beta-galactosidase activity
STSP2_02710	COG0366	Alpha amylase catalytic
STSP2_02711	COG0745	RESPONSE REGULATOR receiver
STSP2_02712	COG5002	protein histidine kinase activity
STSP2_02714	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
STSP2_02715	COG0573	inorganic phosphate transmembrane transporter activity
STSP2_02716	COG0581	inorganic phosphate transmembrane transporter activity
STSP2_02717	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
STSP2_02719	COG0704	Plays a role in the regulation of phosphate uptake
STSP2_02724	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STSP2_02727	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
STSP2_02732	COG2801	Transposase and inactivated derivatives
STSP2_02733	COG5002	protein histidine kinase activity
STSP2_02736	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
STSP2_02739	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
STSP2_02745	COG0515	serine threonine protein kinase
STSP2_02746	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
STSP2_02746	COG0778	Nitroreductase
STSP2_02748	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
STSP2_02752	COG0438	transferase activity, transferring glycosyl groups
STSP2_02756	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STSP2_02757	COG3481	metal-dependent phosphohydrolase, HD sub domain
STSP2_02762	COG1459	type II secretion system
STSP2_02764	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_02769	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
STSP2_02770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STSP2_02773	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_02783	COG1192	Involved in chromosome partitioning
STSP2_02790	COG1045	serine acetyltransferase
STSP2_02792	COG1959	2 iron, 2 sulfur cluster binding
STSP2_02803	COG0438	transferase activity, transferring glycosyl groups
STSP2_02805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
STSP2_02808	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STSP2_02810	COG0508	dehydrogenase complex catalyzes the overall conversion of
STSP2_02813	COG1368	sulfuric ester hydrolase activity
STSP2_02814	COG2207	Transcriptional regulator
STSP2_02815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
STSP2_02816	COG0750	zinc metalloprotease
STSP2_02816	COG0750	zinc metalloprotease
STSP2_02817	COG1216	Glycosyl transferase, family 2
STSP2_02818	COG1216	Glycosyl transferase, family 2
STSP2_02819	COG1216	Glycosyl transferase, family 2
STSP2_02824	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
STSP2_02826	COG0463	Glycosyl transferase, family 2
STSP2_02831	COG1459	type II secretion system
STSP2_02840	COG2088	sporulation resulting in formation of a cellular spore
STSP2_02841	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
STSP2_02845	COG0424	maF-like protein
STSP2_02847	COG1595	DNA-templated transcription, initiation
STSP2_02849	COG0668	transmembrane transport
STSP2_02850	COG1363	Peptidase, m42
STSP2_02852	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
STSP2_02857	COG2866	Carboxypeptidase
STSP2_02858	COG0842	Transport permease protein
STSP2_02859	COG1131	(ABC) transporter
STSP2_02861	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
STSP2_02862	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
STSP2_02864	COG0602	queuosine metabolic process
STSP2_02867	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STSP2_02868	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
STSP2_02871	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
STSP2_02872	COG0261	This protein binds to 23S rRNA in the presence of protein L20
STSP2_02874	COG0428	transporter
STSP2_02877	COG3119	arylsulfatase activity
STSP2_02879	COG3335	DDE superfamily endonuclease
STSP2_02882	COG0758	DNA mediated transformation
STSP2_02882	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
STSP2_02885	COG3676	manually curated
STSP2_02888	COG4251	negative regulation of phosphorylation
STSP2_02889	COG4251	negative regulation of phosphorylation
STSP2_02896	COG0489	protein tyrosine kinase activity
STSP2_02896	COG3206	protein involved in exopolysaccharide biosynthesis
STSP2_02898	COG0708	Exodeoxyribonuclease III
STSP2_02899	COG1131	(ABC) transporter
STSP2_02903	COG1132	(ABC) transporter
STSP2_02905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
STSP2_02906	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STSP2_02907	COG1136	(ABC) transporter
STSP2_02908	COG0577	efflux transmembrane transporter activity
STSP2_02911	COG0237	dephospho-CoA kinase activity
STSP2_02912	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
STSP2_02913	COG0525	valine-tRNA ligase activity
STSP2_02915	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
STSP2_02917	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
STSP2_02918	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
STSP2_02921	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STSP2_02922	COG1120	ATPase activity
STSP2_02923	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
STSP2_02924	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
STSP2_02928	COG2226	methyltransferase
STSP2_02929	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
STSP2_02930	COG1692	metallophosphoesterase
STSP2_02931	COG1418	mRNA catabolic process
STSP2_02938	COG1722	exodeoxyribonuclease VII activity
STSP2_02944	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
STSP2_02944	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
STSP2_02951	COG1028	Short-chain dehydrogenase reductase Sdr
STSP2_02952	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
STSP2_02953	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
STSP2_02955	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
STSP2_02963	COG4796	Type ii and iii secretion system protein
STSP2_02969	COG2165	general secretion pathway protein
STSP2_02971	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STSP2_02972	COG4191	Histidine kinase
STSP2_02976	COG4968	Prepilin-type N-terminal cleavage methylation domain
STSP2_02977	COG1595	DNA-templated transcription, initiation
STSP2_02985	COG2801	Transposase and inactivated derivatives
STSP2_02988	COG0673	inositol 2-dehydrogenase activity
STSP2_02991	COG0673	inositol 2-dehydrogenase activity
STSP2_02992	COG1940	carbohydrate kinase activity
STSP2_02996	COG3119	arylsulfatase activity
STSP2_02998	COG3119	arylsulfatase activity
STSP2_03002	COG0383	alpha-mannosidase activity
STSP2_03014	COG3119	arylsulfatase activity
STSP2_03015	COG3119	arylsulfatase activity
STSP2_03017	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
STSP2_03020	COG2801	Transposase and inactivated derivatives
STSP2_03023	COG0537	adenosine 5'-monophosphoramidase activity
STSP2_03024	COG0203	ribosomal protein L17
STSP2_03025	COG0202	RNA polymerase activity
STSP2_03026	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
STSP2_03027	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
STSP2_03028	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
STSP2_03029	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
STSP2_03030	COG0024	Methionine aminopeptidase
STSP2_03031	COG0563	adenylate kinase activity
STSP2_03032	COG0201	protein transport
STSP2_03033	COG0200	Binds to the 23S rRNA
STSP2_03034	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
STSP2_03035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
STSP2_03037	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
STSP2_03038	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
STSP2_03039	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
STSP2_03040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
STSP2_03041	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
STSP2_03042	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
STSP2_03043	COG0255	Belongs to the universal ribosomal protein uL29 family
STSP2_03044	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
STSP2_03045	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
STSP2_03046	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
STSP2_03047	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
STSP2_03048	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
STSP2_03049	COG0089	rRNA binding
STSP2_03050	COG0088	Forms part of the polypeptide exit tunnel
STSP2_03051	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
STSP2_03052	COG0051	transcription antitermination factor activity, RNA binding
STSP2_03053	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
STSP2_03054	COG0049	tRNA binding
STSP2_03055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
STSP2_03056	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
STSP2_03057	COG0085	RNA polymerase activity
STSP2_03058	COG0222	ribosome binding
STSP2_03059	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
STSP2_03060	COG0081	regulation of translation
STSP2_03061	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
STSP2_03066	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
STSP2_03072	COG0336	Belongs to the RNA methyltransferase TrmD family
STSP2_03076	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
STSP2_03081	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STSP2_03082	COG0335	large ribosomal subunit rRNA binding
STSP2_03083	COG0792	nuclease activity
STSP2_03084	COG0084	hydrolase, TatD family'
STSP2_03086	COG2890	protein-(glutamine-N5) methyltransferase activity
STSP2_03087	COG0017	Asparaginyl-tRNA synthetase
STSP2_03088	COG2731	YhcH YjgK YiaL family protein
STSP2_03090	COG0423	glycine-tRNA ligase activity
STSP2_03093	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
STSP2_03096	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
STSP2_03097	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
STSP2_03105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
STSP2_03107	COG1956	GAF domain-containing protein
STSP2_03108	COG4251	negative regulation of phosphorylation
STSP2_03109	COG4251	negative regulation of phosphorylation
STSP2_03111	COG0442	prolyl-tRNA aminoacylation
STSP2_03113	COG4251	negative regulation of phosphorylation
STSP2_03116	COG3525	Glycosyl hydrolase, family 20, catalytic domain
STSP2_03117	COG0436	Aminotransferase
STSP2_03125	COG3119	arylsulfatase activity
STSP2_03147	COG4980	gas vesicle protein
STSP2_03147	COG1674	ftsk spoiiie
STSP2_03190	COG1830	Aldolase
STSP2_03194	COG1028	Short-chain dehydrogenase reductase Sdr
STSP2_03195	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
STSP2_03197	COG1414	Transcriptional regulator
STSP2_03198	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STSP2_03201	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
STSP2_03203	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STSP2_03212	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
STSP2_03214	COG4956	integral membrane protein (PIN domain superfamily)
STSP2_03215	COG0668	transmembrane transport
STSP2_03222	COG3584	3D domain protein
STSP2_03225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STSP2_03234	COG2207	Transcriptional regulator
STSP2_03234	COG1609	Transcriptional regulator
STSP2_03241	COG1595	DNA-templated transcription, initiation
STSP2_03245	COG2801	Transposase and inactivated derivatives
STSP2_03246	COG0515	serine threonine protein kinase
STSP2_03246	COG2815	serine threonine protein kinase
STSP2_03252	COG2255	four-way junction helicase activity
STSP2_03254	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
STSP2_03264	COG2176	DNA-directed DNA polymerase activity
STSP2_03277	COG1061	Type III restriction enzyme res subunit
STSP2_03287	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STSP2_03301	COG1136	(ABC) transporter
STSP2_03303	COG2205	protein histidine kinase activity
STSP2_03303	COG2198	Histidine kinase
STSP2_03303	COG0784	Response regulator, receiver
STSP2_03304	COG5002	protein histidine kinase activity
STSP2_03306	COG1881	PFAM PEBP family protein
STSP2_03309	COG0544	peptidyl-prolyl cis-trans isomerase activity
STSP2_03310	COG0740	serine-type endopeptidase activity
STSP2_03311	COG0740	serine-type endopeptidase activity
STSP2_03314	COG0815	Transfers the fatty acyl group on membrane lipoproteins
STSP2_03321	COG0768	penicillin binding
STSP2_03324	COG0275	rRNA processing
STSP2_03326	COG2001	Belongs to the MraZ family
STSP2_03330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STSP2_03331	COG2217	Heavy metal translocating P-type atpase
STSP2_03336	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
STSP2_03337	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
STSP2_03338	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
STSP2_03338	COG1796	DNA polymerase
STSP2_03339	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STSP2_03343	COG0438	transferase activity, transferring glycosyl groups
STSP2_03345	COG0693	protein deglycase activity
STSP2_03349	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
STSP2_03354	COG2897	thiosulfate sulfurtransferase activity
STSP2_03358	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
STSP2_03359	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
STSP2_03360	COG0509	glycine decarboxylation via glycine cleavage system
STSP2_03361	COG0404	The glycine cleavage system catalyzes the degradation of glycine
STSP2_03364	COG0443	Heat shock 70 kDa protein
STSP2_03366	COG0275	rRNA processing
STSP2_03369	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
STSP2_03370	COG1691	(AIR) carboxylase
STSP2_03371	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STSP2_03371	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
STSP2_03384	COG0233	cytoplasmic translational termination
STSP2_03385	COG0528	UMP kinase activity
STSP2_03386	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
STSP2_03387	COG0052	Belongs to the universal ribosomal protein uS2 family
STSP2_03389	COG1595	DNA-templated transcription, initiation
STSP2_03391	COG1595	DNA-templated transcription, initiation
STSP2_03392	COG0668	transmembrane transport
STSP2_03393	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
STSP2_03398	COG0101	tRNA pseudouridine synthase activity
STSP2_03399	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STSP2_03401	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
STSP2_03402	COG3046	protein related to deoxyribodipyrimidine photolyase
STSP2_03407	COG0778	Nitroreductase
STSP2_03409	COG1181	Belongs to the D-alanine--D-alanine ligase family
STSP2_03410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
STSP2_03411	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
STSP2_03412	COG0357	Ribosomal RNA small subunit methyltransferase G
STSP2_03414	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
STSP2_03415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STSP2_03416	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
STSP2_03417	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
STSP2_03421	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STSP2_03423	COG3335	DDE superfamily endonuclease
STSP2_03428	COG0518	GMP synthase (glutamine-hydrolyzing) activity
STSP2_03428	COG0519	Catalyzes the synthesis of GMP from XMP
STSP2_03429	COG0517	IMP dehydrogenase activity
STSP2_03429	COG0516	GMP reductase activity
STSP2_03432	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
STSP2_03438	COG0673	inositol 2-dehydrogenase activity
STSP2_03439	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
STSP2_03442	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
STSP2_03443	COG1993	acr, cog1993
STSP2_03444	COG0612	Peptidase, M16
STSP2_03446	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
STSP2_03447	COG0540	Belongs to the ATCase OTCase family
STSP2_03448	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
STSP2_03453	COG1214	PFAM Peptidase M22, glycoprotease
STSP2_03454	COG0459	protein refolding
STSP2_03455	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
STSP2_03456	COG0459	protein refolding
STSP2_03457	COG0484	heat shock protein binding
STSP2_03458	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
STSP2_03461	COG0285	dihydrofolate synthase activity
STSP2_03468	COG1136	(ABC) transporter
STSP2_03469	COG0577	efflux transmembrane transporter activity
STSP2_03469	COG1136	(ABC) transporter
STSP2_03470	COG0142	geranyltranstransferase activity
STSP2_03472	COG1136	(ABC) transporter
STSP2_03475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
STSP2_03476	COG0793	Belongs to the peptidase S41A family
STSP2_03477	COG0191	fructose-bisphosphate aldolase activity
STSP2_03483	COG3387	PFAM Glycoside hydrolase 15-related
STSP2_03485	COG4968	Prepilin-type N-terminal cleavage methylation domain
STSP2_03486	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
STSP2_03487	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
STSP2_03493	COG0045	succinate-CoA ligase (ADP-forming) activity
STSP2_03494	COG1725	Transcriptional regulator
STSP2_03507	COG3676	manually curated
STSP2_03508	COG0084	hydrolase, TatD family'
STSP2_03509	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
STSP2_03512	COG3039	Transposase
STSP2_03514	COG0840	transmembrane signaling receptor activity
STSP2_03518	COG0667	Aldo Keto reductase
STSP2_03519	COG1414	Transcriptional regulator
STSP2_03521	COG2314	TM2 domain
STSP2_03522	COG0330	HflC and HflK could
STSP2_03526	COG4585	Histidine kinase
STSP2_03529	COG1477	protein flavinylation
STSP2_03532	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
STSP2_03534	COG1509	lysine 2,3-aminomutase activity
STSP2_03535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
STSP2_03536	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
STSP2_03537	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STSP2_03542	COG0438	transferase activity, transferring glycosyl groups
STSP2_03551	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
STSP2_03554	COG0404	The glycine cleavage system catalyzes the degradation of glycine
STSP2_03558	COG1137	ATPase activity
STSP2_03559	COG0242	peptide deformylase activity
STSP2_03560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
STSP2_03561	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STSP2_03561	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons