locus-tag	class	description
G4Y79_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G4Y79_00025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G4Y79_00045	COG0739	heme binding
G4Y79_00045	COG0741	lytic transglycosylase activity
G4Y79_00045	COG1196	nuclear chromosome segregation
G4Y79_00060	COG1404	Belongs to the peptidase S8 family
G4Y79_00115	COG0419	ATPase involved in DNA repair
G4Y79_00120	COG2124	cytochrome p450
G4Y79_00130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4Y79_00150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G4Y79_00175	COG0174	glutamine synthetase
G4Y79_00215	COG1674	ftsk spoiiie
G4Y79_00230	COG5002	protein histidine kinase activity
G4Y79_00235	COG1803	Methylglyoxal synthase
G4Y79_00235	COG1597	lipid kinase activity
G4Y79_00280	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G4Y79_00305	COG1506	peptidase
G4Y79_00305	COG4946	Tricorn protease homolog
G4Y79_00305	COG0823	Involved in the tonB-independent uptake of proteins
G4Y79_00310	COG1672	PFAM Archaeal ATPase
G4Y79_00310	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G4Y79_00355	COG0081	regulation of translation
G4Y79_00360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G4Y79_00365	COG0250	Participates in transcription elongation, termination and antitermination
G4Y79_00380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G4Y79_00405	COG0412	Dienelactone hydrolase
G4Y79_00415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G4Y79_00450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G4Y79_00460	COG2226	methyltransferase
G4Y79_00470	COG0395	ABC-type sugar transport system, permease component
G4Y79_00485	COG1595	DNA-templated transcription, initiation
G4Y79_00495	COG2124	cytochrome p450
G4Y79_00575	COG1234	tRNA 3'-trailer cleavage
G4Y79_00585	COG2815	serine threonine protein kinase
G4Y79_00585	COG0515	serine threonine protein kinase
G4Y79_00610	COG0420	3'-5' exonuclease activity
G4Y79_00685	COG3347	Dehydrogenase
G4Y79_00685	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_00700	COG1070	Carbohydrate kinase
G4Y79_00705	COG1216	Glycosyl transferase, family 2
G4Y79_00705	COG0463	Glycosyl transferase, family 2
G4Y79_00710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G4Y79_00715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4Y79_00735	COG0583	DNA-binding transcription factor activity
G4Y79_00775	COG0295	cytidine deaminase activity
G4Y79_00785	COG5504	Zn-dependent protease
G4Y79_00790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4Y79_00790	COG2169	Transcriptional regulator
G4Y79_00800	COG2815	serine threonine protein kinase
G4Y79_00800	COG0515	serine threonine protein kinase
G4Y79_00825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4Y79_00835	COG0456	acetyltransferase
G4Y79_00870	COG2234	aminopeptidase activity
G4Y79_00875	COG1069	ribulokinase activity
G4Y79_00880	COG0235	Class ii aldolase
G4Y79_00885	COG2160	L-arabinose isomerase activity
G4Y79_00890	COG1063	alcohol dehydrogenase
G4Y79_00900	COG2205	protein histidine kinase activity
G4Y79_00915	COG0471	metal ion transport
G4Y79_00915	COG0490	domain, Protein
G4Y79_00920	COG0631	protein serine/threonine phosphatase activity
G4Y79_00930	COG0456	acetyltransferase
G4Y79_00940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G4Y79_00945	COG0477	Major facilitator Superfamily
G4Y79_00960	COG4956	integral membrane protein (PIN domain superfamily)
G4Y79_00970	COG4251	negative regulation of phosphorylation
G4Y79_01010	COG0475	glutathione-regulated potassium exporter activity
G4Y79_01025	COG0745	RESPONSE REGULATOR receiver
G4Y79_01045	COG2217	Heavy metal translocating P-type atpase
G4Y79_01130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4Y79_01135	COG0514	ATP-dependent DNA helicase (RecQ)
G4Y79_01175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4Y79_01205	COG2442	InterPro IPR007367
G4Y79_01225	COG3186	Phenylalanine-4-hydroxylase
G4Y79_01235	COG1192	Involved in chromosome partitioning
G4Y79_01250	COG0358	DNA primase activity
G4Y79_01265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G4Y79_01270	COG2201	protein-glutamate methylesterase activity
G4Y79_01305	COG3118	belongs to the thioredoxin family
G4Y79_01330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4Y79_01375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4Y79_01425	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G4Y79_01430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G4Y79_01445	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G4Y79_01470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G4Y79_01520	COG0328	RNA-DNA hybrid ribonuclease activity
G4Y79_01525	COG3118	belongs to the thioredoxin family
G4Y79_01545	COG1742	UPF0060 membrane protein
G4Y79_01570	COG2264	protein methyltransferase activity
G4Y79_01625	COG2072	flavoprotein involved in K transport
G4Y79_01630	COG0640	Transcriptional regulator
G4Y79_01655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G4Y79_01655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G4Y79_01665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4Y79_01685	COG0785	Cytochrome C biogenesis protein
G4Y79_01700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4Y79_01715	COG0501	Belongs to the peptidase M48B family
G4Y79_01735	COG1136	(ABC) transporter
G4Y79_01740	COG0577	efflux transmembrane transporter activity
G4Y79_01775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4Y79_01845	COG5433	transposase activity
G4Y79_01855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G4Y79_01895	COG2217	Heavy metal translocating P-type atpase
G4Y79_01900	COG2197	response regulator
G4Y79_01925	COG2197	response regulator
G4Y79_01940	COG5002	protein histidine kinase activity
G4Y79_01945	COG0745	RESPONSE REGULATOR receiver
G4Y79_01955	COG2217	Heavy metal translocating P-type atpase
G4Y79_01960	COG2217	Heavy metal translocating P-type atpase
G4Y79_01985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G4Y79_02005	COG1192	Involved in chromosome partitioning
G4Y79_02010	COG0745	RESPONSE REGULATOR receiver
G4Y79_02030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4Y79_02085	COG0714	Associated with various cellular activities
G4Y79_02150	COG1215	transferase activity, transferring glycosyl groups
G4Y79_02175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G4Y79_02180	COG2890	protein-(glutamine-N5) methyltransferase activity
G4Y79_02185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4Y79_02210	COG0745	RESPONSE REGULATOR receiver
G4Y79_02215	COG0670	Belongs to the BI1 family
G4Y79_02220	COG0824	Thioesterase
G4Y79_02225	COG0285	dihydrofolate synthase activity
G4Y79_02230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4Y79_02235	COG0515	serine threonine protein kinase
G4Y79_02235	COG2815	serine threonine protein kinase
G4Y79_02240	COG0622	Phosphoesterase
G4Y79_02245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4Y79_02260	COG0494	nUDIX hydrolase
G4Y79_02280	COG2226	methyltransferase
G4Y79_02285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4Y79_02290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4Y79_02290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_02295	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4Y79_02310	COG0336	Belongs to the RNA methyltransferase TrmD family
G4Y79_02320	COG1716	ATPase activity
G4Y79_02325	COG2271	Major facilitator Superfamily
G4Y79_02335	COG0492	ferredoxin-NADP+ reductase activity
G4Y79_02345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4Y79_02350	COG0784	Response regulator, receiver
G4Y79_02360	COG2204	response regulator
G4Y79_02365	COG2204	response regulator
G4Y79_02375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4Y79_02400	COG1316	TRANSCRIPTIONal
G4Y79_02405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4Y79_02430	COG1215	transferase activity, transferring glycosyl groups
G4Y79_02445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G4Y79_02445	COG0646	methionine synthase
G4Y79_02470	COG2226	methyltransferase
G4Y79_02510	COG1802	Transcriptional regulator
G4Y79_02515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G4Y79_02525	COG0436	Aminotransferase
G4Y79_02535	COG1363	Peptidase, m42
G4Y79_02540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_02550	COG0747	negative chemotaxis
G4Y79_02575	COG2382	esterase
G4Y79_02580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G4Y79_02590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4Y79_02595	COG0490	domain, Protein
G4Y79_02595	COG0471	metal ion transport
G4Y79_02610	COG0745	RESPONSE REGULATOR receiver
G4Y79_02640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G4Y79_02650	COG0151	Belongs to the GarS family
G4Y79_02655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G4Y79_02660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G4Y79_02670	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G4Y79_02675	COG0667	Aldo Keto reductase
G4Y79_02680	COG0667	Aldo Keto reductase
G4Y79_02685	COG0789	Transcriptional regulator
G4Y79_02685	COG4978	Transcriptional regulator
G4Y79_02725	COG0697	spore germination
G4Y79_02785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G4Y79_02790	COG1501	Belongs to the glycosyl hydrolase 31 family
G4Y79_02795	COG1501	Belongs to the glycosyl hydrolase 31 family
G4Y79_02805	COG1175	transmembrane transport
G4Y79_02825	COG2124	cytochrome p450
G4Y79_02845	COG4585	Histidine kinase
G4Y79_02850	COG0477	Major facilitator Superfamily
G4Y79_02865	COG4166	transmembrane transport
G4Y79_02875	COG2365	Tyrosine phosphatase family
G4Y79_02885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_02905	COG1233	COG1233 Phytoene dehydrogenase and related
G4Y79_02915	COG0395	ABC-type sugar transport system, permease component
G4Y79_02920	COG1175	transmembrane transport
G4Y79_02935	COG1609	Transcriptional regulator
G4Y79_02940	COG1486	melibiose metabolic process
G4Y79_02945	COG3940	Belongs to the glycosyl hydrolase 43 family
G4Y79_02955	COG1609	Transcriptional regulator
G4Y79_02965	COG1175	transmembrane transport
G4Y79_02990	COG0457	Tetratricopeptide repeat
G4Y79_03000	COG4608	Belongs to the ABC transporter superfamily
G4Y79_03005	COG0444	Belongs to the ABC transporter superfamily
G4Y79_03010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_03020	COG0747	negative chemotaxis
G4Y79_03050	COG0745	RESPONSE REGULATOR receiver
G4Y79_03055	COG0531	amino acid
G4Y79_03065	COG2205	protein histidine kinase activity
G4Y79_03070	COG2342	PFAM TM1410 hypothetical-related protein
G4Y79_03075	COG0395	ABC-type sugar transport system, permease component
G4Y79_03080	COG1175	transmembrane transport
G4Y79_03090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G4Y79_03095	COG1486	melibiose metabolic process
G4Y79_03100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4Y79_03105	COG3684	Belongs to the aldolase LacD family
G4Y79_03110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4Y79_03120	COG1105	Belongs to the carbohydrate kinase PfkB family
G4Y79_03140	COG3250	beta-galactosidase activity
G4Y79_03150	COG0395	ABC-type sugar transport system, permease component
G4Y79_03160	COG1609	Transcriptional regulator
G4Y79_03175	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G4Y79_03180	COG0154	amidase activity
G4Y79_03190	COG2815	serine threonine protein kinase
G4Y79_03190	COG0515	serine threonine protein kinase
G4Y79_03270	COG0154	amidase activity
G4Y79_03280	COG0789	Transcriptional regulator
G4Y79_03285	COG0667	Aldo Keto reductase
G4Y79_03295	COG0330	HflC and HflK could
G4Y79_03305	COG0528	UMP kinase activity
G4Y79_03310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G4Y79_03315	COG0052	Belongs to the universal ribosomal protein uS2 family
G4Y79_03320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G4Y79_03330	COG0251	oxidation-reduction process
G4Y79_03360	COG2378	regulation of single-species biofilm formation
G4Y79_03380	COG0667	Aldo Keto reductase
G4Y79_03390	COG1501	Belongs to the glycosyl hydrolase 31 family
G4Y79_03395	COG4608	Belongs to the ABC transporter superfamily
G4Y79_03400	COG0444	Belongs to the ABC transporter superfamily
G4Y79_03405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_03410	COG0601	transmembrane transport
G4Y79_03415	COG0747	negative chemotaxis
G4Y79_03420	COG1609	Transcriptional regulator
G4Y79_03430	COG3338	carbonate dehydratase activity
G4Y79_03470	COG1335	isochorismatase
G4Y79_03480	COG0456	acetyltransferase
G4Y79_03505	COG0745	RESPONSE REGULATOR receiver
G4Y79_03510	COG5002	protein histidine kinase activity
G4Y79_03515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G4Y79_03520	COG0494	nUDIX hydrolase
G4Y79_03525	COG1716	ATPase activity
G4Y79_03545	COG1131	(ABC) transporter
G4Y79_03575	COG0372	Belongs to the citrate synthase family
G4Y79_03650	COG0513	Belongs to the DEAD box helicase family
G4Y79_03655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_03680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G4Y79_03750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G4Y79_03755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4Y79_03760	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_03770	COG2267	carboxylic ester hydrolase activity
G4Y79_03790	COG0488	(ABC) transporter
G4Y79_03800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4Y79_03820	COG1733	regulation of RNA biosynthetic process
G4Y79_03840	COG2226	methyltransferase
G4Y79_03840	COG1073	alpha beta
G4Y79_03845	COG2815	serine threonine protein kinase
G4Y79_03845	COG0515	serine threonine protein kinase
G4Y79_03870	COG5183	chlorophyll binding
G4Y79_03870	COG2133	pyrroloquinoline quinone binding
G4Y79_03890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4Y79_03905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G4Y79_03910	COG2009	succinate dehydrogenase
G4Y79_03915	COG1053	succinate dehydrogenase
G4Y79_03920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G4Y79_03940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G4Y79_03950	COG0673	inositol 2-dehydrogenase activity
G4Y79_03960	COG0470	DNA polymerase III
G4Y79_03965	COG1403	HNH endonuclease
G4Y79_03970	COG0281	malic enzyme
G4Y79_03970	COG0280	phosphate acetyltransferase
G4Y79_04015	COG1196	nuclear chromosome segregation
G4Y79_04015	COG0741	lytic transglycosylase activity
G4Y79_04015	COG0739	heme binding
G4Y79_04045	COG0539	negative regulation of cytoplasmic translation
G4Y79_04050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G4Y79_04085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G4Y79_04110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4Y79_04120	COG0497	DNA recombination
G4Y79_04130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G4Y79_04135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G4Y79_04140	COG0573	inorganic phosphate transmembrane transporter activity
G4Y79_04145	COG0581	inorganic phosphate transmembrane transporter activity
G4Y79_04150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4Y79_04160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4Y79_04165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G4Y79_04205	COG0367	asparagine synthase
G4Y79_04220	COG0205	6-phosphofructokinase activity
G4Y79_04230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4Y79_04235	COG0616	signal peptide processing
G4Y79_04240	COG3173	Aminoglycoside phosphotransferase
G4Y79_04250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4Y79_04265	COG0534	Mate efflux family protein
G4Y79_04290	COG0515	serine threonine protein kinase
G4Y79_04290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G4Y79_04320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4Y79_04380	COG1111	helicase
G4Y79_04380	COG1205	dead DEAH box helicase
G4Y79_04385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4Y79_04395	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G4Y79_04415	COG0629	single-stranded DNA binding
G4Y79_04440	COG2319	Wd-40 repeat
G4Y79_04475	COG1487	ribonuclease activity
G4Y79_04490	COG0328	RNA-DNA hybrid ribonuclease activity
G4Y79_04505	COG0587	DNA-directed DNA polymerase activity
G4Y79_04545	COG2894	cell division
G4Y79_04585	COG4249	Peptidase C14 caspase catalytic subunit p20
G4Y79_04585	COG2319	Wd-40 repeat
G4Y79_04600	COG2202	Pas domain
G4Y79_04600	COG2205	protein histidine kinase activity
G4Y79_04615	COG1175	transmembrane transport
G4Y79_04620	COG0395	ABC-type sugar transport system, permease component
G4Y79_04625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4Y79_04630	COG3534	alpha-L-arabinofuranosidase
G4Y79_04690	COG1846	Transcriptional regulator
G4Y79_04690	COG1940	carbohydrate kinase activity
G4Y79_04695	COG1175	transmembrane transport
G4Y79_04700	COG0395	ABC-type sugar transport system, permease component
G4Y79_04710	COG1501	Belongs to the glycosyl hydrolase 31 family
G4Y79_04760	COG0535	radical SAM domain protein
G4Y79_04765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G4Y79_04770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4Y79_04820	COG1999	signal sequence binding
G4Y79_04855	COG0745	RESPONSE REGULATOR receiver
G4Y79_04860	COG5002	protein histidine kinase activity
G4Y79_04865	COG1136	(ABC) transporter
G4Y79_04880	COG4213	ABC transporter substrate-binding protein
G4Y79_04890	COG4214	carbohydrate transport
G4Y79_04905	COG2207	Transcriptional regulator
G4Y79_04910	COG2272	Belongs to the type-B carboxylesterase lipase family
G4Y79_04920	COG3119	arylsulfatase activity
G4Y79_04930	COG2197	response regulator
G4Y79_04935	COG4585	Histidine kinase
G4Y79_04945	COG1653	transport
G4Y79_04950	COG1175	transmembrane transport
G4Y79_04955	COG0395	ABC-type sugar transport system, permease component
G4Y79_04970	COG0673	inositol 2-dehydrogenase activity
G4Y79_04975	COG1609	Transcriptional regulator
G4Y79_04985	COG1175	transmembrane transport
G4Y79_04990	COG0395	ABC-type sugar transport system, permease component
G4Y79_04995	COG0656	L-ascorbic acid biosynthetic process
G4Y79_05005	COG4977	sequence-specific DNA binding
G4Y79_05015	COG0395	ABC-type sugar transport system, permease component
G4Y79_05020	COG1175	transmembrane transport
G4Y79_05050	COG2909	trisaccharide binding
G4Y79_05075	COG4636	protein conserved in cyanobacteria
G4Y79_05130	COG2319	Wd-40 repeat
G4Y79_05130	COG4249	Peptidase C14 caspase catalytic subunit p20
G4Y79_05135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4Y79_05295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G4Y79_05315	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G4Y79_05325	COG1079	Belongs to the binding-protein-dependent transport system permease family
G4Y79_05330	COG4603	Belongs to the binding-protein-dependent transport system permease family
G4Y79_05335	COG2258	MOSC domain
G4Y79_05355	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G4Y79_05390	COG2720	vancomycin resistance protein
G4Y79_05400	COG0438	transferase activity, transferring glycosyl groups
G4Y79_05405	COG0438	transferase activity, transferring glycosyl groups
G4Y79_05420	COG2318	DinB family
G4Y79_05440	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G4Y79_05445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4Y79_05450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G4Y79_05455	COG1012	belongs to the aldehyde dehydrogenase family
G4Y79_05485	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_05490	COG3119	arylsulfatase activity
G4Y79_05500	COG3250	beta-galactosidase activity
G4Y79_05515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G4Y79_05525	COG5002	protein histidine kinase activity
G4Y79_05530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4Y79_05580	COG1879	ABC-type sugar transport system periplasmic component
G4Y79_05585	COG1609	Transcriptional regulator
G4Y79_05590	COG1879	ABC-type sugar transport system periplasmic component
G4Y79_05595	COG1129	ABC transporter
G4Y79_05600	COG1172	Belongs to the binding-protein-dependent transport system permease family
G4Y79_05605	COG1172	Belongs to the binding-protein-dependent transport system permease family
G4Y79_05610	COG0784	Response regulator, receiver
G4Y79_05610	COG2205	protein histidine kinase activity
G4Y79_05610	COG5002	protein histidine kinase activity
G4Y79_05620	COG4565	transcriptional regulatory protein
G4Y79_05635	COG0596	Alpha beta hydrolase
G4Y79_05660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4Y79_05680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4Y79_05830	COG2154	pterin-4-alpha-carbinolamine dehydratase
G4Y79_05840	COG2270	Major facilitator Superfamily
G4Y79_05865	COG0784	Response regulator, receiver
G4Y79_05870	COG4999	Histidine kinase
G4Y79_05870	COG3437	response regulator, receiver
G4Y79_05870	COG2205	protein histidine kinase activity
G4Y79_05870	COG3850	Histidine kinase
G4Y79_05880	COG0745	RESPONSE REGULATOR receiver
G4Y79_05885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4Y79_05905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4Y79_05925	COG1376	ErfK ybiS ycfS ynhG family protein
G4Y79_05930	COG0346	lactoylglutathione lyase activity
G4Y79_05940	COG0105	UTP biosynthetic process
G4Y79_05980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G4Y79_06000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4Y79_06015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4Y79_06030	COG0515	serine threonine protein kinase
G4Y79_06030	COG2815	serine threonine protein kinase
G4Y79_06040	COG0438	transferase activity, transferring glycosyl groups
G4Y79_06045	COG0297	glycogen (starch) synthase activity
G4Y79_06080	COG0012	GTP binding
G4Y79_06115	COG5002	protein histidine kinase activity
G4Y79_06120	COG0784	Response regulator, receiver
G4Y79_06125	COG4251	negative regulation of phosphorylation
G4Y79_06145	COG3622	Belongs to the hyi family
G4Y79_06150	COG3845	ABC transporter
G4Y79_06210	COG0372	Belongs to the citrate synthase family
G4Y79_06215	COG1051	belongs to the nudix hydrolase family
G4Y79_06220	COG1051	belongs to the nudix hydrolase family
G4Y79_06240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G4Y79_06270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G4Y79_06290	COG4948	Mandelate Racemase Muconate Lactonizing
G4Y79_06300	COG0489	protein tyrosine kinase activity
G4Y79_06340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4Y79_06350	COG1136	(ABC) transporter
G4Y79_06355	COG1136	(ABC) transporter
G4Y79_06375	COG0745	RESPONSE REGULATOR receiver
G4Y79_06380	COG5002	protein histidine kinase activity
G4Y79_06385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G4Y79_06385	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G4Y79_06415	COG2198	Histidine kinase
G4Y79_06415	COG0784	Response regulator, receiver
G4Y79_06415	COG2205	protein histidine kinase activity
G4Y79_06420	COG2205	protein histidine kinase activity
G4Y79_06460	COG3119	arylsulfatase activity
G4Y79_06465	COG1368	sulfuric ester hydrolase activity
G4Y79_06470	COG3119	arylsulfatase activity
G4Y79_06475	COG0395	ABC-type sugar transport system, permease component
G4Y79_06490	COG1609	Transcriptional regulator
G4Y79_06495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4Y79_06500	COG0156	8-amino-7-oxononanoate synthase activity
G4Y79_06510	COG0477	Major facilitator Superfamily
G4Y79_06515	COG3842	ATPase activity
G4Y79_06520	COG0395	ABC-type sugar transport system, permease component
G4Y79_06535	COG2133	pyrroloquinoline quinone binding
G4Y79_06535	COG5183	chlorophyll binding
G4Y79_06540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G4Y79_06555	COG1653	transport
G4Y79_06570	COG3119	arylsulfatase activity
G4Y79_06575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4Y79_06580	COG1486	melibiose metabolic process
G4Y79_06600	COG0542	response to heat
G4Y79_06610	COG0641	radical SAM
G4Y79_06625	COG0693	protein deglycase activity
G4Y79_06635	COG4572	Cation transport regulator
G4Y79_06650	COG4572	Cation transport regulator
G4Y79_06660	COG1285	pathogenesis
G4Y79_06670	COG0631	protein serine/threonine phosphatase activity
G4Y79_06685	COG2197	response regulator
G4Y79_06690	COG4585	Histidine kinase
G4Y79_06695	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
G4Y79_06705	COG3142	Participates in the control of copper homeostasis
G4Y79_06710	COG0673	inositol 2-dehydrogenase activity
G4Y79_06720	COG1940	carbohydrate kinase activity
G4Y79_06745	COG4608	Belongs to the ABC transporter superfamily
G4Y79_06755	COG1940	carbohydrate kinase activity
G4Y79_06765	COG3661	Belongs to the glycosyl hydrolase 67 family
G4Y79_06770	COG1063	alcohol dehydrogenase
G4Y79_06775	COG1472	Belongs to the glycosyl hydrolase 3 family
G4Y79_06785	COG0667	Aldo Keto reductase
G4Y79_06790	COG0587	DNA-directed DNA polymerase activity
G4Y79_06800	COG0740	serine-type endopeptidase activity
G4Y79_06805	COG1595	DNA-templated transcription, initiation
G4Y79_06810	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G4Y79_06815	COG1012	belongs to the aldehyde dehydrogenase family
G4Y79_06820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G4Y79_06825	COG1312	Catalyzes the dehydration of D-mannonate
G4Y79_06840	COG3876	Protein conserved in bacteria
G4Y79_06845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G4Y79_06850	COG4608	Belongs to the ABC transporter superfamily
G4Y79_06855	COG0444	Belongs to the ABC transporter superfamily
G4Y79_06860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_06865	COG0601	transmembrane transport
G4Y79_06870	COG4166	transmembrane transport
G4Y79_06875	COG0515	serine threonine protein kinase
G4Y79_06875	COG2815	serine threonine protein kinase
G4Y79_06880	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G4Y79_06885	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
G4Y79_06890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G4Y79_06895	COG0113	porphobilinogen synthase activity
G4Y79_06900	COG1587	Uroporphyrinogen-III synthase
G4Y79_06905	COG0181	hydroxymethylbilane synthase activity
G4Y79_06910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G4Y79_06915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G4Y79_06920	COG2146	nitrite reductase [NAD(P)H] activity
G4Y79_06925	COG0175	sulfate reduction
G4Y79_06935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G4Y79_06935	COG1648	precorrin-2 dehydrogenase activity
G4Y79_06945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G4Y79_06945	COG1648	precorrin-2 dehydrogenase activity
G4Y79_06955	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4Y79_06975	COG0673	inositol 2-dehydrogenase activity
G4Y79_06980	COG0673	inositol 2-dehydrogenase activity
G4Y79_06985	COG1902	pentaerythritol trinitrate reductase activity
G4Y79_06995	COG1802	Transcriptional regulator
G4Y79_07000	COG0673	inositol 2-dehydrogenase activity
G4Y79_07005	COG1904	glucuronate isomerase
G4Y79_07010	COG0246	Mannitol dehydrogenase
G4Y79_07015	COG2721	sulfolactate sulfo-lyase activity
G4Y79_07045	COG0395	ABC-type sugar transport system, permease component
G4Y79_07075	COG5487	UPF0391 membrane protein
G4Y79_07080	COG0783	Belongs to the Dps family
G4Y79_07095	COG0628	permease
G4Y79_07105	COG2198	Histidine kinase
G4Y79_07105	COG0784	Response regulator, receiver
G4Y79_07105	COG5002	protein histidine kinase activity
G4Y79_07110	COG2205	protein histidine kinase activity
G4Y79_07120	COG1295	ribonuclease BN
G4Y79_07140	COG2308	Evidence 4 Homologs of previously reported genes of
G4Y79_07150	COG1305	Transglutaminase-like
G4Y79_07155	COG1609	Transcriptional regulator
G4Y79_07160	COG0747	negative chemotaxis
G4Y79_07165	COG0601	transmembrane transport
G4Y79_07170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_07175	COG0444	Belongs to the ABC transporter superfamily
G4Y79_07180	COG4608	Belongs to the ABC transporter superfamily
G4Y79_07205	COG0673	inositol 2-dehydrogenase activity
G4Y79_07210	COG0673	inositol 2-dehydrogenase activity
G4Y79_07215	COG4948	Mandelate Racemase Muconate Lactonizing
G4Y79_07220	COG0803	Belongs to the bacterial solute-binding protein 9 family
G4Y79_07225	COG1121	(ABC) transporter
G4Y79_07230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4Y79_07235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4Y79_07240	COG5002	protein histidine kinase activity
G4Y79_07240	COG3850	Histidine kinase
G4Y79_07250	COG3250	beta-galactosidase activity
G4Y79_07255	COG1217	gtp-binding protein TYPA
G4Y79_07265	COG1045	serine acetyltransferase
G4Y79_07285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G4Y79_07285	COG0473	3-isopropylmalate dehydrogenase activity
G4Y79_07295	COG4948	Mandelate Racemase Muconate Lactonizing
G4Y79_07300	COG1063	alcohol dehydrogenase
G4Y79_07310	COG2186	Transcriptional regulator
G4Y79_07325	COG0395	ABC-type sugar transport system, permease component
G4Y79_07340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G4Y79_07345	COG3386	PFAM SMP-30 Gluconolaconase
G4Y79_07365	COG1609	Transcriptional regulator
G4Y79_07375	COG1181	Belongs to the D-alanine--D-alanine ligase family
G4Y79_07380	COG0154	amidase activity
G4Y79_07390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4Y79_07395	COG0745	RESPONSE REGULATOR receiver
G4Y79_07410	COG1309	transcriptional regulator
G4Y79_07420	COG0640	Transcriptional regulator
G4Y79_07455	COG1716	ATPase activity
G4Y79_07465	COG0799	negative regulation of ribosome biogenesis
G4Y79_07470	COG3263	regulation of cellular component size
G4Y79_07480	COG0564	pseudouridine synthase activity
G4Y79_07485	COG5002	protein histidine kinase activity
G4Y79_07500	COG0484	heat shock protein binding
G4Y79_07505	COG0387	Pfam Sodium calcium exchanger
G4Y79_07515	COG3854	ATPases associated with a variety of cellular activities
G4Y79_07525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_07545	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G4Y79_07555	COG4221	oxidoreductase activity
G4Y79_07610	COG0739	heme binding
G4Y79_07660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4Y79_07665	COG1349	DNA-binding transcription factor activity
G4Y79_07670	COG1070	Carbohydrate kinase
G4Y79_07690	COG0667	Aldo Keto reductase
G4Y79_07730	COG2359	stage V sporulation protein S
G4Y79_07740	COG1381	Involved in DNA repair and RecF pathway recombination
G4Y79_07745	COG1285	pathogenesis
G4Y79_07770	COG0006	proline dipeptidase activity
G4Y79_07785	COG5002	protein histidine kinase activity
G4Y79_07870	COG0735	belongs to the Fur family
G4Y79_07895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4Y79_07895	COG0438	transferase activity, transferring glycosyl groups
G4Y79_07910	COG0730	response to heat
G4Y79_07920	COG0667	Aldo Keto reductase
G4Y79_07930	COG2062	phosphohistidine phosphatase, SixA
G4Y79_07935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4Y79_07950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G4Y79_07995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4Y79_07995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4Y79_08000	COG0662	Cupin 2, conserved barrel domain protein
G4Y79_08015	COG0017	Asparaginyl-tRNA synthetase
G4Y79_08020	COG1832	CoA-binding protein
G4Y79_08030	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G4Y79_08035	COG2207	Transcriptional regulator
G4Y79_08035	COG1917	Cupin 2, conserved barrel domain protein
G4Y79_08065	COG0038	chloride channel
G4Y79_08070	COG2192	nodulation
G4Y79_08125	COG0784	Response regulator, receiver
G4Y79_08125	COG2205	protein histidine kinase activity
G4Y79_08125	COG5002	protein histidine kinase activity
G4Y79_08140	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G4Y79_08150	COG0277	FAD linked oxidase domain protein
G4Y79_08170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G4Y79_08175	COG0698	ribose 5-phosphate isomerase
G4Y79_08200	COG0802	atpase or kinase
G4Y79_08205	COG1214	PFAM Peptidase M22, glycoprotease
G4Y79_08255	COG0631	protein serine/threonine phosphatase activity
G4Y79_08260	COG0745	RESPONSE REGULATOR receiver
G4Y79_08270	COG1794	racemase activity, acting on amino acids and derivatives
G4Y79_08300	COG0736	holo-[acyl-carrier-protein] synthase activity
G4Y79_08310	COG3340	Belongs to the peptidase S51 family
G4Y79_08325	COG3485	protocatechuate 3,4-dioxygenase
G4Y79_08340	COG4608	Belongs to the ABC transporter superfamily
G4Y79_08345	COG0444	Belongs to the ABC transporter superfamily
G4Y79_08355	COG0521	Mo-molybdopterin cofactor biosynthetic process
G4Y79_08360	COG1515	deoxyribonuclease V activity
G4Y79_08375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G4Y79_08390	COG0473	3-isopropylmalate dehydrogenase activity
G4Y79_08400	COG0768	penicillin binding
G4Y79_08405	COG1280	lysine exporter protein (LysE YggA)
G4Y79_08420	COG1950	PFAM Membrane protein of
G4Y79_08425	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_08450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4Y79_08485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4Y79_08490	COG0393	Putative heavy-metal-binding
G4Y79_08495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G4Y79_08495	COG0519	Catalyzes the synthesis of GMP from XMP
G4Y79_08505	COG0215	cysteine-tRNA ligase activity
G4Y79_08510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4Y79_08515	COG0233	cytoplasmic translational termination
G4Y79_08585	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
G4Y79_08635	COG0004	ammonium transporteR
G4Y79_08650	COG2816	NAD+ diphosphatase activity
G4Y79_08700	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G4Y79_08765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4Y79_08770	COG4589	Belongs to the CDS family
G4Y79_08775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G4Y79_08780	COG0438	transferase activity, transferring glycosyl groups
G4Y79_08785	COG1051	belongs to the nudix hydrolase family
G4Y79_08790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
G4Y79_08805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4Y79_08830	COG2072	flavoprotein involved in K transport
G4Y79_08855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4Y79_08865	COG0672	)-iron permease
G4Y79_08875	COG0672	)-iron permease
G4Y79_08885	COG2197	response regulator
G4Y79_08925	COG4659	FMN binding
G4Y79_08950	COG1120	ATPase activity
G4Y79_08960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4Y79_08995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4Y79_09000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4Y79_09005	COG0469	pyruvate kinase activity
G4Y79_09035	COG0483	inositol monophosphate 1-phosphatase activity
G4Y79_09040	COG1278	Cold shock
G4Y79_09085	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G4Y79_09090	COG2267	carboxylic ester hydrolase activity
G4Y79_09100	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G4Y79_09105	COG0612	Peptidase, M16
G4Y79_09145	COG2353	YceI-like domain
G4Y79_09150	COG0237	dephospho-CoA kinase activity
G4Y79_09175	COG0438	transferase activity, transferring glycosyl groups
G4Y79_09200	COG0823	Involved in the tonB-independent uptake of proteins
G4Y79_09230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G4Y79_09310	COG0300	oxidoreductase activity
G4Y79_09320	COG0583	DNA-binding transcription factor activity
G4Y79_09325	COG4221	oxidoreductase activity
G4Y79_09345	COG0697	spore germination
G4Y79_09350	COG0789	Transcriptional regulator
G4Y79_09365	COG1595	DNA-templated transcription, initiation
G4Y79_09405	COG1609	Transcriptional regulator
G4Y79_09415	COG1175	transmembrane transport
G4Y79_09425	COG1472	Belongs to the glycosyl hydrolase 3 family
G4Y79_09440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G4Y79_09445	COG3250	beta-galactosidase activity
G4Y79_09450	COG1609	Transcriptional regulator
G4Y79_09465	COG0747	negative chemotaxis
G4Y79_09495	COG0489	protein tyrosine kinase activity
G4Y79_09500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G4Y79_09505	COG4988	ABC transporter
G4Y79_09510	COG1294	oxidase, subunit
G4Y79_09515	COG1271	oxidase subunit
G4Y79_09520	COG1486	melibiose metabolic process
G4Y79_09530	COG0395	ABC-type sugar transport system, permease component
G4Y79_09535	COG1175	transmembrane transport
G4Y79_09585	COG2205	protein histidine kinase activity
G4Y79_09590	COG0745	RESPONSE REGULATOR receiver
G4Y79_09595	COG0531	amino acid
G4Y79_09605	COG1175	transmembrane transport
G4Y79_09610	COG0395	ABC-type sugar transport system, permease component
G4Y79_09615	COG0004	ammonium transporteR
G4Y79_09620	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G4Y79_09625	COG4946	Tricorn protease homolog
G4Y79_09625	COG1506	peptidase
G4Y79_09625	COG0823	Involved in the tonB-independent uptake of proteins
G4Y79_09640	COG4948	Mandelate Racemase Muconate Lactonizing
G4Y79_09645	COG0456	acetyltransferase
G4Y79_09665	COG0601	transmembrane transport
G4Y79_09670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_09685	COG0523	cobalamin synthesis protein
G4Y79_09690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4Y79_09695	COG1121	(ABC) transporter
G4Y79_09700	COG0803	Belongs to the bacterial solute-binding protein 9 family
G4Y79_09720	COG0402	S-adenosylhomocysteine deaminase activity
G4Y79_09725	COG0583	DNA-binding transcription factor activity
G4Y79_09750	COG1573	uracil-dna glycosylase
G4Y79_09760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G4Y79_09795	COG0405	Gamma-glutamyltransferase
G4Y79_09805	COG4977	sequence-specific DNA binding
G4Y79_09810	COG0384	phenazine biosynthesis protein PhzF
G4Y79_09830	COG3964	amidohydrolase
G4Y79_09835	COG3942	CHAP domain
G4Y79_09835	COG1388	LysM domain
G4Y79_09850	COG0305	Participates in initiation and elongation during chromosome replication
G4Y79_09860	COG1484	DNA-dependent DNA replication
G4Y79_09870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G4Y79_09900	COG0835	chemotaxis
G4Y79_09915	COG2201	protein-glutamate methylesterase activity
G4Y79_09935	COG0835	chemotaxis
G4Y79_09940	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G4Y79_09945	COG1609	Transcriptional regulator
G4Y79_09955	COG0601	transmembrane transport
G4Y79_09965	COG0444	Belongs to the ABC transporter superfamily
G4Y79_09980	COG3408	Glycogen debranching enzyme
G4Y79_09985	COG1472	Belongs to the glycosyl hydrolase 3 family
G4Y79_09990	COG2272	Belongs to the type-B carboxylesterase lipase family
G4Y79_10010	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G4Y79_10035	COG2197	response regulator
G4Y79_10040	COG4585	Histidine kinase
G4Y79_10045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G4Y79_10055	COG3958	Transketolase
G4Y79_10060	COG3959	Transketolase, thiamine diphosphate binding domain
G4Y79_10075	COG1053	succinate dehydrogenase
G4Y79_10085	COG0326	Molecular chaperone. Has ATPase activity
G4Y79_10100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G4Y79_10105	COG1609	Transcriptional regulator
G4Y79_10110	COG1472	Belongs to the glycosyl hydrolase 3 family
G4Y79_10115	COG2273	Hydrolase Family 16
G4Y79_10115	COG5297	Belongs to the glycosyl hydrolase family 6
G4Y79_10150	COG0179	Fumarylacetoacetate (FAA) hydrolase
G4Y79_10155	COG0129	dihydroxy-acid dehydratase activity
G4Y79_10185	COG2205	protein histidine kinase activity
G4Y79_10185	COG3437	response regulator, receiver
G4Y79_10185	COG4999	Histidine kinase
G4Y79_10185	COG3850	Histidine kinase
G4Y79_10230	COG1490	D-aminoacyl-tRNA deacylase activity
G4Y79_10250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4Y79_10265	COG0009	L-threonylcarbamoyladenylate synthase
G4Y79_10275	COG0686	Belongs to the AlaDH PNT family
G4Y79_10290	COG0427	acetyl-CoA hydrolase
G4Y79_10300	COG1595	DNA-templated transcription, initiation
G4Y79_10310	COG0085	RNA polymerase activity
G4Y79_10320	COG0438	transferase activity, transferring glycosyl groups
G4Y79_10340	COG0752	glycyl-tRNA synthetase alpha subunit
G4Y79_10340	COG0751	glycine-tRNA ligase activity
G4Y79_10345	COG0305	Participates in initiation and elongation during chromosome replication
G4Y79_10345	COG0358	DNA primase activity
G4Y79_10355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4Y79_10380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G4Y79_10385	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G4Y79_10390	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G4Y79_10395	COG0649	NAD binding
G4Y79_10415	COG1034	ATP synthesis coupled electron transport
G4Y79_10420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G4Y79_10425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G4Y79_10430	COG0839	Belongs to the complex I subunit 6 family
G4Y79_10435	COG0713	ATP synthesis coupled electron transport
G4Y79_10450	COG1007	ATP synthesis coupled electron transport
G4Y79_10465	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
G4Y79_10470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G4Y79_10475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G4Y79_10480	COG0193	aminoacyl-tRNA hydrolase activity
G4Y79_10495	COG1132	(ABC) transporter
G4Y79_10520	COG1131	(ABC) transporter
G4Y79_10550	COG1309	transcriptional regulator
G4Y79_10565	COG1231	oxidoreductase activity
G4Y79_10595	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G4Y79_10600	COG0049	tRNA binding
G4Y79_10605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G4Y79_10610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G4Y79_10615	COG0051	transcription antitermination factor activity, RNA binding
G4Y79_10620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G4Y79_10625	COG0088	Forms part of the polypeptide exit tunnel
G4Y79_10630	COG0089	rRNA binding
G4Y79_10635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G4Y79_10640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G4Y79_10645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G4Y79_10650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G4Y79_10655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G4Y79_10660	COG0255	Belongs to the universal ribosomal protein uL29 family
G4Y79_10665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G4Y79_10670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G4Y79_10675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G4Y79_10680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G4Y79_10690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G4Y79_10695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G4Y79_10700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G4Y79_10705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G4Y79_10710	COG1841	ribosomal large subunit assembly
G4Y79_10715	COG0200	Binds to the 23S rRNA
G4Y79_10725	COG0563	adenylate kinase activity
G4Y79_10740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G4Y79_10755	COG0202	RNA polymerase activity
G4Y79_10775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G4Y79_10790	COG3956	TIGRFAM MazG family protein
G4Y79_10825	COG0859	PFAM glycosyl transferase family 9
G4Y79_10830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G4Y79_10830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G4Y79_10840	COG3695	enzyme binding
G4Y79_10845	COG1418	mRNA catabolic process
G4Y79_10850	COG2137	regulation of response to DNA damage stimulus
G4Y79_10855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4Y79_10875	COG0287	Prephenate dehydrogenase
G4Y79_10885	COG1994	Peptidase M50
G4Y79_10890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4Y79_10895	COG2329	Antibiotic biosynthesis monooxygenase
G4Y79_10900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G4Y79_10915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G4Y79_10920	COG5002	protein histidine kinase activity
G4Y79_10930	COG5002	protein histidine kinase activity
G4Y79_10935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G4Y79_10940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G4Y79_10945	COG2198	Histidine kinase
G4Y79_10945	COG0784	Response regulator, receiver
G4Y79_10945	COG2205	protein histidine kinase activity
G4Y79_10955	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G4Y79_10990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_11005	COG2897	thiosulfate sulfurtransferase activity
G4Y79_11030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G4Y79_11035	COG1480	7TM receptor with intracellular HD hydrolase
G4Y79_11040	COG1610	YqeY-like protein
G4Y79_11045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4Y79_11060	COG0745	RESPONSE REGULATOR receiver
G4Y79_11090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G4Y79_11095	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G4Y79_11100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4Y79_11105	COG0589	response to stress
G4Y79_11110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G4Y79_11115	COG4585	Histidine kinase
G4Y79_11125	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G4Y79_11135	COG1716	ATPase activity
G4Y79_11140	COG1136	(ABC) transporter
G4Y79_11145	COG0517	IMP dehydrogenase activity
G4Y79_11150	COG0517	IMP dehydrogenase activity
G4Y79_11160	COG2197	response regulator
G4Y79_11165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G4Y79_11170	COG0456	acetyltransferase
G4Y79_11175	COG2814	Major facilitator Superfamily
G4Y79_11200	COG1960	acyl-CoA dehydrogenase activity
G4Y79_11215	COG0613	PHP domain protein
G4Y79_11220	COG0745	RESPONSE REGULATOR receiver
G4Y79_11225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G4Y79_11230	COG1234	tRNA 3'-trailer cleavage
G4Y79_11240	COG4555	ABC transporter
G4Y79_11245	COG0745	RESPONSE REGULATOR receiver
G4Y79_11250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G4Y79_11255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G4Y79_11285	COG1073	alpha beta
G4Y79_11310	COG0517	IMP dehydrogenase activity
G4Y79_11320	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G4Y79_11325	COG3639	organic phosphonate transmembrane transporter activity
G4Y79_11330	COG1132	(ABC) transporter
G4Y79_11335	COG1132	(ABC) transporter
G4Y79_11345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_11355	COG0823	Involved in the tonB-independent uptake of proteins
G4Y79_11355	COG1506	peptidase
G4Y79_11355	COG4946	Tricorn protease homolog
G4Y79_11365	COG0747	negative chemotaxis
G4Y79_11370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_11375	COG0601	transmembrane transport
G4Y79_11385	COG0745	RESPONSE REGULATOR receiver
G4Y79_11390	COG2205	protein histidine kinase activity
G4Y79_11410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4Y79_11420	COG1653	transport
G4Y79_11425	COG1175	transmembrane transport
G4Y79_11430	COG0395	ABC-type sugar transport system, permease component
G4Y79_11450	COG0745	RESPONSE REGULATOR receiver
G4Y79_11455	COG5002	protein histidine kinase activity
G4Y79_11455	COG0784	Response regulator, receiver
G4Y79_11455	COG2205	protein histidine kinase activity
G4Y79_11470	COG0438	transferase activity, transferring glycosyl groups
G4Y79_11510	COG4251	negative regulation of phosphorylation
G4Y79_11515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_11520	COG0601	transmembrane transport
G4Y79_11535	COG0395	ABC-type sugar transport system, permease component
G4Y79_11540	COG1175	transmembrane transport
G4Y79_11550	COG0745	RESPONSE REGULATOR receiver
G4Y79_11555	COG2205	protein histidine kinase activity
G4Y79_11555	COG2202	Pas domain
G4Y79_11565	COG0395	ABC-type sugar transport system, permease component
G4Y79_11570	COG1175	transmembrane transport
G4Y79_11575	COG1609	Transcriptional regulator
G4Y79_11580	COG3250	beta-galactosidase activity
G4Y79_11585	COG1053	succinate dehydrogenase
G4Y79_11590	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G4Y79_11615	COG1609	Transcriptional regulator
G4Y79_11625	COG1175	transmembrane transport
G4Y79_11630	COG0395	ABC-type sugar transport system, permease component
G4Y79_11635	COG3119	arylsulfatase activity
G4Y79_11660	COG3842	ATPase activity
G4Y79_11665	COG1555	photosystem II stabilization
G4Y79_11670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G4Y79_11680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G4Y79_11700	COG0384	phenazine biosynthesis protein PhzF
G4Y79_11710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G4Y79_11715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4Y79_11725	COG0463	Glycosyl transferase, family 2
G4Y79_11735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G4Y79_11775	COG2207	Transcriptional regulator
G4Y79_11775	COG1917	Cupin 2, conserved barrel domain protein
G4Y79_11790	COG1175	transmembrane transport
G4Y79_11795	COG0395	ABC-type sugar transport system, permease component
G4Y79_11800	COG1473	amidohydrolase
G4Y79_11815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4Y79_11820	COG2226	methyltransferase
G4Y79_11825	COG0640	Transcriptional regulator
G4Y79_11840	COG0745	RESPONSE REGULATOR receiver
G4Y79_11870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G4Y79_11880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G4Y79_11880	COG0189	ligase activity
G4Y79_11890	COG1091	dTDP-4-dehydrorhamnose reductase activity
G4Y79_11895	COG1216	Glycosyl transferase, family 2
G4Y79_11900	COG0463	Glycosyl transferase, family 2
G4Y79_11905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G4Y79_11910	COG2226	methyltransferase
G4Y79_11930	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G4Y79_11935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4Y79_11945	COG1088	dTDP-glucose 4,6-dehydratase activity
G4Y79_11950	COG0561	phosphatase activity
G4Y79_11960	COG0489	protein tyrosine kinase activity
G4Y79_11965	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_11970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4Y79_11985	COG1054	Belongs to the UPF0176 family
G4Y79_11990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G4Y79_12020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_12020	COG0045	succinate-CoA ligase (ADP-forming) activity
G4Y79_12020	COG1042	CoA-binding domain protein
G4Y79_12025	COG1320	monovalent cation:proton antiporter activity
G4Y79_12030	COG2212	antiporter activity
G4Y79_12035	COG1863	multisubunit Na H antiporter MnhE subunit
G4Y79_12040	COG0651	ATP synthesis coupled electron transport
G4Y79_12045	COG1006	Multisubunit Na H antiporter MnhC subunit
G4Y79_12050	COG2111	Na H antiporter
G4Y79_12050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G4Y79_12055	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G4Y79_12100	COG1960	acyl-CoA dehydrogenase activity
G4Y79_12145	COG0372	Belongs to the citrate synthase family
G4Y79_12205	COG2770	Histidine kinase
G4Y79_12205	COG2208	phosphoserine phosphatase activity
G4Y79_12210	COG0494	nUDIX hydrolase
G4Y79_12215	COG0628	permease
G4Y79_12245	COG3191	aminopeptidase activity
G4Y79_12250	COG0745	RESPONSE REGULATOR receiver
G4Y79_12260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4Y79_12265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4Y79_12270	COG1116	anion transmembrane transporter activity
G4Y79_12280	COG5002	protein histidine kinase activity
G4Y79_12285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4Y79_12295	COG0745	RESPONSE REGULATOR receiver
G4Y79_12310	COG3685	Protein conserved in bacteria
G4Y79_12315	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_12325	COG1523	belongs to the glycosyl hydrolase 13 family
G4Y79_12355	COG1918	ferrous iron import across plasma membrane
G4Y79_12365	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G4Y79_12365	COG1918	ferrous iron import across plasma membrane
G4Y79_12385	COG0583	DNA-binding transcription factor activity
G4Y79_12400	COG2197	response regulator
G4Y79_12405	COG4585	Histidine kinase
G4Y79_12410	COG0583	DNA-binding transcription factor activity
G4Y79_12415	COG2855	membrane
G4Y79_12420	COG1053	succinate dehydrogenase
G4Y79_12425	COG1233	COG1233 Phytoene dehydrogenase and related
G4Y79_12430	COG2186	Transcriptional regulator
G4Y79_12435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G4Y79_12450	COG0601	transmembrane transport
G4Y79_12455	COG2186	Transcriptional regulator
G4Y79_12460	COG2207	Transcriptional regulator
G4Y79_12460	COG1917	Cupin 2, conserved barrel domain protein
G4Y79_12490	COG1053	succinate dehydrogenase
G4Y79_12495	COG2124	cytochrome p450
G4Y79_12495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4Y79_12500	COG1309	transcriptional regulator
G4Y79_12550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G4Y79_12560	COG0667	Aldo Keto reductase
G4Y79_12570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G4Y79_12585	COG1307	EDD domain protein, DegV family
G4Y79_12590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G4Y79_12595	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G4Y79_12620	COG1295	ribonuclease BN
G4Y79_12620	COG1959	2 iron, 2 sulfur cluster binding
G4Y79_12635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G4Y79_12640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G4Y79_12640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G4Y79_12655	COG0674	pyruvate-flavodoxin oxidoreductase activity
G4Y79_12655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G4Y79_12670	COG1428	Deoxynucleoside kinase
G4Y79_12695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G4Y79_12700	COG2226	methyltransferase
G4Y79_12705	COG0583	DNA-binding transcription factor activity
G4Y79_12715	COG0537	adenosine 5'-monophosphoramidase activity
G4Y79_12720	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_12725	COG1506	peptidase
G4Y79_12725	COG4946	Tricorn protease homolog
G4Y79_12725	COG0823	Involved in the tonB-independent uptake of proteins
G4Y79_12735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G4Y79_12760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G4Y79_12765	COG1040	competence protein
G4Y79_12785	COG2197	response regulator
G4Y79_12810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G4Y79_12815	COG0762	integral membrane protein
G4Y79_12875	COG1733	regulation of RNA biosynthetic process
G4Y79_12895	COG4191	Histidine kinase
G4Y79_12900	COG0745	RESPONSE REGULATOR receiver
G4Y79_12920	COG0667	Aldo Keto reductase
G4Y79_12925	COG4604	ABC transporter, ATP-binding protein
G4Y79_12930	COG4605	iron ion homeostasis
G4Y79_12935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4Y79_12940	COG4607	ABC-type enterochelin transport system periplasmic component
G4Y79_12980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4Y79_13000	COG3620	sequence-specific DNA binding
G4Y79_13000	COG0617	tRNA 3'-terminal CCA addition
G4Y79_13000	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G4Y79_13035	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G4Y79_13065	COG2188	Transcriptional regulator
G4Y79_13070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_13075	COG0601	transmembrane transport
G4Y79_13090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G4Y79_13105	COG0601	transmembrane transport
G4Y79_13110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_13115	COG0747	negative chemotaxis
G4Y79_13120	COG0601	transmembrane transport
G4Y79_13125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_13130	COG0606	chelatase, subunit chli
G4Y79_13150	COG3001	Fructosamine kinase
G4Y79_13155	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_13210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4Y79_13225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G4Y79_13230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G4Y79_13235	COG0204	Acyl-transferase
G4Y79_13240	COG1187	pseudouridine synthase activity
G4Y79_13250	COG0745	RESPONSE REGULATOR receiver
G4Y79_13265	COG1181	Belongs to the D-alanine--D-alanine ligase family
G4Y79_13270	COG1253	flavin adenine dinucleotide binding
G4Y79_13275	COG0739	heme binding
G4Y79_13275	COG1196	nuclear chromosome segregation
G4Y79_13275	COG0741	lytic transglycosylase activity
G4Y79_13280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G4Y79_13285	COG0596	Alpha beta hydrolase
G4Y79_13300	COG2313	pseudouridylate synthase activity
G4Y79_13320	COG2135	peptidase activity
G4Y79_13325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G4Y79_13330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G4Y79_13335	COG1674	ftsk spoiiie
G4Y79_13335	COG4980	gas vesicle protein
G4Y79_13360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4Y79_13380	COG1131	(ABC) transporter
G4Y79_13385	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G4Y79_13390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G4Y79_13395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4Y79_13400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G4Y79_13405	COG0505	Belongs to the CarA family
G4Y79_13410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G4Y79_13425	COG0443	Heat shock 70 kDa protein
G4Y79_13430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G4Y79_13445	COG0617	tRNA 3'-terminal CCA addition
G4Y79_13450	COG0742	ribosomal rna small subunit methyltransferase
G4Y79_13480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G4Y79_13515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G4Y79_13520	COG2508	Transcriptional regulator
G4Y79_13525	COG0067	glutamate synthase
G4Y79_13525	COG0069	glutamate synthase activity
G4Y79_13525	COG0070	glutamate synthase
G4Y79_13530	COG2508	Transcriptional regulator
G4Y79_13545	COG1316	TRANSCRIPTIONal
G4Y79_13570	COG0594	ribonuclease P activity
G4Y79_13575	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G4Y79_13585	COG0706	membrane insertase activity
G4Y79_13590	COG1847	R3H domain protein
G4Y79_13600	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G4Y79_13610	COG0556	nucleotide-excision repair
G4Y79_13625	COG0019	diaminopimelate decarboxylase activity
G4Y79_13630	COG1160	GTP binding
G4Y79_13635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G4Y79_13640	COG1285	pathogenesis
G4Y79_13650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4Y79_13685	COG0095	Lipoate-protein ligase
G4Y79_13695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G4Y79_13700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G4Y79_13710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G4Y79_13710	COG1796	DNA polymerase
G4Y79_13725	COG0512	Glutamine amidotransferase of anthranilate synthase
G4Y79_13725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G4Y79_13740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G4Y79_13745	COG0134	indole-3-glycerol-phosphate synthase activity
G4Y79_13750	COG0135	phosphoribosylanthranilate isomerase activity
G4Y79_13760	COG0133	tryptophan synthase activity
G4Y79_13770	COG0159	tryptophan synthase activity
G4Y79_13780	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G4Y79_13785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G4Y79_13795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G4Y79_13800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G4Y79_13805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G4Y79_13810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G4Y79_13825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G4Y79_13835	COG0527	aspartate kinase activity
G4Y79_13835	COG0460	homoserine dehydrogenase
G4Y79_13840	COG1774	PSP1 C-terminal conserved region
G4Y79_13845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4Y79_13850	COG1473	amidohydrolase
G4Y79_13860	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G4Y79_13865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4Y79_13870	COG5002	protein histidine kinase activity
G4Y79_13880	COG1612	heme a metabolic process
G4Y79_13885	COG1612	heme a metabolic process
G4Y79_13885	COG0109	protoheme IX farnesyltransferase activity
G4Y79_13895	COG1293	RNA-binding protein homologous to eukaryotic snRNP
G4Y79_13900	COG2326	polyphosphate kinase activity
G4Y79_13905	COG0859	PFAM glycosyl transferase family 9
G4Y79_13910	COG0438	transferase activity, transferring glycosyl groups
G4Y79_13935	COG0515	serine threonine protein kinase
G4Y79_13935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G4Y79_13940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G4Y79_13945	COG4948	Mandelate Racemase Muconate Lactonizing
G4Y79_13955	COG1312	Catalyzes the dehydration of D-mannonate
G4Y79_13960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4Y79_13965	COG0667	Aldo Keto reductase
G4Y79_13980	COG1595	DNA-templated transcription, initiation
G4Y79_13995	COG2814	Major facilitator Superfamily
G4Y79_14000	COG0395	ABC-type sugar transport system, permease component
G4Y79_14005	COG1175	transmembrane transport
G4Y79_14025	COG4977	sequence-specific DNA binding
G4Y79_14040	COG0667	Aldo Keto reductase
G4Y79_14095	COG2197	response regulator
G4Y79_14105	COG2217	Heavy metal translocating P-type atpase
G4Y79_14145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G4Y79_14155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4Y79_14160	COG0662	Cupin 2, conserved barrel domain protein
G4Y79_14160	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G4Y79_14165	COG0758	DNA mediated transformation
G4Y79_14165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G4Y79_14170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G4Y79_14175	COG1837	Belongs to the UPF0109 family
G4Y79_14180	COG0228	four-way junction DNA binding
G4Y79_14185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G4Y79_14190	COG2814	Major facilitator Superfamily
G4Y79_14195	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G4Y79_14200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4Y79_14210	COG0728	peptidoglycan biosynthetic process
G4Y79_14230	COG0772	Belongs to the SEDS family
G4Y79_14235	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G4Y79_14240	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_14250	COG1716	ATPase activity
G4Y79_14250	COG5001	Diguanylate cyclase
G4Y79_14260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4Y79_14265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G4Y79_14270	COG0629	single-stranded DNA binding
G4Y79_14275	COG0360	Binds together with S18 to 16S ribosomal RNA
G4Y79_14295	COG1216	Glycosyl transferase, family 2
G4Y79_14300	COG0084	hydrolase, TatD family'
G4Y79_14325	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G4Y79_14330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4Y79_14365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4Y79_14370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G4Y79_14380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G4Y79_14385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G4Y79_14395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4Y79_14400	COG1690	Belongs to the RtcB family
G4Y79_14405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4Y79_14420	COG3409	Peptidoglycan-binding domain 1 protein
G4Y79_14420	COG0793	Belongs to the peptidase S41A family
G4Y79_14435	COG4143	(ABC) transporter
G4Y79_14440	COG1178	ABC-type Fe3 transport system permease component
G4Y79_14445	COG3842	ATPase activity
G4Y79_14450	COG2723	6-phospho-beta-galactosidase activity
G4Y79_14455	COG0187	DNA topoisomerase II activity
G4Y79_14465	COG1192	Involved in chromosome partitioning
G4Y79_14530	COG2052	Domain of unknown function (DUF370)
G4Y79_14635	COG1053	succinate dehydrogenase
G4Y79_14645	COG2197	response regulator
G4Y79_14665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4Y79_14675	COG1138	Cytochrome C-type biogenesis protein
G4Y79_14690	COG0318	PFAM AMP-dependent synthetase and ligase
G4Y79_14695	COG0824	Thioesterase
G4Y79_14705	COG0107	imidazoleglycerol-phosphate synthase activity
G4Y79_14710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G4Y79_14715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G4Y79_14730	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G4Y79_14735	COG0515	serine threonine protein kinase
G4Y79_14735	COG2815	serine threonine protein kinase
G4Y79_14740	COG1705	Flagellar rod assembly protein muramidase FlgJ
G4Y79_14740	COG1388	LysM domain
G4Y79_14780	COG1862	Preprotein translocase
G4Y79_14785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4Y79_14790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4Y79_14795	COG5002	protein histidine kinase activity
G4Y79_14800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G4Y79_14805	COG0745	RESPONSE REGULATOR receiver
G4Y79_14810	COG5002	protein histidine kinase activity
G4Y79_14815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G4Y79_14840	COG0525	valine-tRNA ligase activity
G4Y79_14845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4Y79_14860	COG0138	bifunctional purine biosynthesis protein purh
G4Y79_14885	COG2192	nodulation
G4Y79_14900	COG2897	thiosulfate sulfurtransferase activity
G4Y79_14910	COG0438	transferase activity, transferring glycosyl groups
G4Y79_14920	COG0137	argininosuccinate synthase activity
G4Y79_14925	COG0165	Argininosuccinate lyase
G4Y79_14930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4Y79_14935	COG0028	Belongs to the TPP enzyme family
G4Y79_14940	COG0440	acetolactate synthase activity
G4Y79_14945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G4Y79_14950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G4Y79_14955	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G4Y79_14960	COG0778	Nitroreductase
G4Y79_14965	COG0066	3-isopropylmalate dehydratase activity
G4Y79_14970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G4Y79_14990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G4Y79_14995	COG0626	cystathionine gamma-synthase activity
G4Y79_15000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G4Y79_15005	COG0083	homoserine kinase activity
G4Y79_15010	COG1012	belongs to the aldehyde dehydrogenase family
G4Y79_15020	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G4Y79_15025	COG0649	NAD binding
G4Y79_15035	COG0489	protein tyrosine kinase activity
G4Y79_15065	COG5002	protein histidine kinase activity
G4Y79_15075	COG1316	TRANSCRIPTIONal
G4Y79_15085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_15090	COG0601	transmembrane transport
G4Y79_15095	COG0747	negative chemotaxis
G4Y79_15115	COG1192	Involved in chromosome partitioning
G4Y79_15375	COG0582	viral genome integration into host DNA
G4Y79_15410	COG2151	metal-sulfur cluster biosynthetic enzyme
G4Y79_15415	COG0396	ATPase activity
G4Y79_15420	COG0719	Fe-S assembly protein
G4Y79_15425	COG0719	Fe-S assembly protein
G4Y79_15430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4Y79_15435	COG0822	iron-sulfur transferase activity
G4Y79_15445	COG0584	glycerophosphoryl diester phosphodiesterase
G4Y79_15450	COG2226	methyltransferase
G4Y79_15485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G4Y79_15485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G4Y79_15500	COG1011	Hydrolase
G4Y79_15510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G4Y79_15510	COG1199	ATP-dependent helicase activity
G4Y79_15520	COG2346	COG2346, Truncated hemoglobins
G4Y79_15535	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
G4Y79_15540	COG0632	four-way junction helicase activity
G4Y79_15545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G4Y79_15550	COG0217	transcriptional regulatory protein
G4Y79_15560	COG2003	Belongs to the UPF0758 family
G4Y79_15575	COG0148	phosphopyruvate hydratase activity
G4Y79_15580	COG1104	cysteine desulfurase activity
G4Y79_15585	COG0482	sulfurtransferase activity
G4Y79_15635	COG0739	heme binding
G4Y79_15645	COG3942	CHAP domain
G4Y79_15645	COG1388	LysM domain
G4Y79_15650	COG1550	Protein conserved in bacteria
G4Y79_15670	COG2304	oxidoreductase activity
G4Y79_15690	COG0714	Associated with various cellular activities
G4Y79_15695	COG1435	thymidine kinase activity
G4Y79_15710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G4Y79_15730	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G4Y79_15735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4Y79_15745	COG0149	triose-phosphate isomerase activity
G4Y79_15750	COG0515	serine threonine protein kinase
G4Y79_15750	COG2815	serine threonine protein kinase
G4Y79_15760	COG0126	phosphoglycerate kinase activity
G4Y79_15760	COG0149	triose-phosphate isomerase activity
G4Y79_15765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4Y79_15770	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G4Y79_15790	COG0714	Associated with various cellular activities
G4Y79_15800	COG0504	CTP synthase activity
G4Y79_15810	COG0443	Heat shock 70 kDa protein
G4Y79_15820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4Y79_15825	COG2084	Dehydrogenase
G4Y79_15835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G4Y79_15880	COG0631	protein serine/threonine phosphatase activity
G4Y79_15885	COG0515	serine threonine protein kinase
G4Y79_15890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4Y79_15900	COG1304	FMN binding
G4Y79_15905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4Y79_15920	COG1607	acyl-coa hydrolase
G4Y79_15925	COG0438	transferase activity, transferring glycosyl groups
G4Y79_15940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4Y79_15960	COG2890	protein-(glutamine-N5) methyltransferase activity
G4Y79_15975	COG5002	protein histidine kinase activity
G4Y79_15990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G4Y79_16005	COG0416	fatty acid biosynthetic process
G4Y79_16020	COG4191	Histidine kinase
G4Y79_16025	COG0793	Belongs to the peptidase S41A family
G4Y79_16030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G4Y79_16055	COG1739	Uncharacterized protein family UPF0029
G4Y79_16075	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G4Y79_16080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G4Y79_16090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G4Y79_16110	COG0316	Belongs to the HesB IscA family
G4Y79_16120	COG3409	Peptidoglycan-binding domain 1 protein
G4Y79_16120	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4Y79_16150	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G4Y79_16150	COG0546	phosphoglycolate phosphatase activity
G4Y79_16155	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G4Y79_16165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_16170	COG0601	transmembrane transport
G4Y79_16175	COG0747	negative chemotaxis
G4Y79_16195	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G4Y79_16200	COG0481	GTPase activity
G4Y79_16215	COG1546	Belongs to the CinA family
G4Y79_16215	COG1058	Belongs to the CinA family
G4Y79_16220	COG3842	ATPase activity
G4Y79_16260	COG0156	8-amino-7-oxononanoate synthase activity
G4Y79_16265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4Y79_16270	COG1132	(ABC) transporter
G4Y79_16275	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G4Y79_16275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G4Y79_16300	COG0667	Aldo Keto reductase
G4Y79_16315	COG1136	(ABC) transporter
G4Y79_16325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4Y79_16330	COG1174	glycine betaine transport
G4Y79_16340	COG1174	glycine betaine transport
G4Y79_16360	COG0444	Belongs to the ABC transporter superfamily
G4Y79_16365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_16370	COG0601	transmembrane transport
G4Y79_16375	COG0747	negative chemotaxis
G4Y79_16380	COG1609	Transcriptional regulator
G4Y79_16405	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_16420	COG4191	Histidine kinase
G4Y79_16425	COG0784	Response regulator, receiver
G4Y79_16450	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G4Y79_16455	COG4297	protein containing double-stranded beta helix domain
G4Y79_16460	COG4106	trans-aconitate 2-methyltransferase activity
G4Y79_16485	COG1175	transmembrane transport
G4Y79_16490	COG0395	ABC-type sugar transport system, permease component
G4Y79_16530	COG0577	efflux transmembrane transporter activity
G4Y79_16535	COG1136	(ABC) transporter
G4Y79_16545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4Y79_16555	COG4585	Histidine kinase
G4Y79_16560	COG2197	response regulator
G4Y79_16570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_16580	COG1254	Belongs to the acylphosphatase family
G4Y79_16585	COG3534	alpha-L-arabinofuranosidase
G4Y79_16595	COG1653	transport
G4Y79_16600	COG0395	ABC-type sugar transport system, permease component
G4Y79_16605	COG1175	transmembrane transport
G4Y79_16615	COG0395	ABC-type sugar transport system, permease component
G4Y79_16620	COG1175	transmembrane transport
G4Y79_16665	COG3903	Transcriptional regulator
G4Y79_16665	COG2319	Wd-40 repeat
G4Y79_16675	COG0395	ABC-type sugar transport system, permease component
G4Y79_16680	COG1175	transmembrane transport
G4Y79_16695	COG1082	Xylose isomerase domain protein TIM barrel
G4Y79_16700	COG2186	Transcriptional regulator
G4Y79_16710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_16715	COG0601	transmembrane transport
G4Y79_16730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4Y79_16865	COG2909	trisaccharide binding
G4Y79_16900	COG0673	inositol 2-dehydrogenase activity
G4Y79_16905	COG1414	Transcriptional regulator
G4Y79_16915	COG3718	enzyme involved in inositol metabolism
G4Y79_16920	COG3962	Belongs to the TPP enzyme family
G4Y79_16925	COG0673	inositol 2-dehydrogenase activity
G4Y79_16930	COG3684	Belongs to the aldolase LacD family
G4Y79_16945	COG1703	isobutyryl-CoA mutase activity
G4Y79_16955	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G4Y79_16960	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G4Y79_16970	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4Y79_16975	COG0567	Dehydrogenase, E1 component
G4Y79_16985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G4Y79_16995	COG1136	(ABC) transporter
G4Y79_17000	COG1136	(ABC) transporter
G4Y79_17015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G4Y79_17020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G4Y79_17025	COG0363	glucosamine-6-phosphate deaminase activity
G4Y79_17030	COG0540	Belongs to the ATCase OTCase family
G4Y79_17035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G4Y79_17040	COG0167	dihydroorotate dehydrogenase activity
G4Y79_17045	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G4Y79_17050	COG0284	orotidine-5'-phosphate decarboxylase activity
G4Y79_17065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G4Y79_17070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4Y79_17085	COG0415	Belongs to the DNA photolyase family
G4Y79_17100	COG0039	L-malate dehydrogenase activity
G4Y79_17105	COG1562	ergosterol biosynthetic process
G4Y79_17130	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G4Y79_17145	COG0123	including yeast histone deacetylase and acetoin utilization protein
G4Y79_17150	COG1012	belongs to the aldehyde dehydrogenase family
G4Y79_17150	COG2030	dehydratase
G4Y79_17165	COG2205	protein histidine kinase activity
G4Y79_17165	COG3437	response regulator, receiver
G4Y79_17165	COG4999	Histidine kinase
G4Y79_17165	COG3850	Histidine kinase
G4Y79_17170	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G4Y79_17175	COG0792	nuclease activity
G4Y79_17180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G4Y79_17190	COG0745	RESPONSE REGULATOR receiver
G4Y79_17195	COG0784	Response regulator, receiver
G4Y79_17195	COG2205	protein histidine kinase activity
G4Y79_17200	COG5002	protein histidine kinase activity
G4Y79_17230	COG0402	S-adenosylhomocysteine deaminase activity
G4Y79_17245	COG0571	ribonuclease III activity
G4Y79_17250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4Y79_17255	COG0314	molybdopterin synthase activity
G4Y79_17260	COG0315	cyclic pyranopterin monophosphate synthase activity
G4Y79_17265	COG0552	protein localization to endoplasmic reticulum
G4Y79_17275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G4Y79_17290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G4Y79_17300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G4Y79_17315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G4Y79_17320	COG0303	'Molybdopterin
G4Y79_17330	COG0539	negative regulation of cytoplasmic translation
G4Y79_17330	COG2183	response to ionizing radiation
G4Y79_17345	COG0739	heme binding
G4Y79_17355	COG1388	LysM domain
G4Y79_17355	COG3942	CHAP domain
G4Y79_17370	COG1027	Aspartate ammonia-lyase
G4Y79_17375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G4Y79_17380	COG0697	spore germination
G4Y79_17395	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G4Y79_17400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G4Y79_17420	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G4Y79_17425	COG0740	serine-type endopeptidase activity
G4Y79_17430	COG0544	peptidyl-prolyl cis-trans isomerase activity
G4Y79_17450	COG1136	(ABC) transporter
G4Y79_17450	COG0577	efflux transmembrane transporter activity
G4Y79_17455	COG0577	efflux transmembrane transporter activity
G4Y79_17455	COG1136	(ABC) transporter
G4Y79_17460	COG0577	efflux transmembrane transporter activity
G4Y79_17460	COG1136	(ABC) transporter
G4Y79_17470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4Y79_17475	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G4Y79_17490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G4Y79_17495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G4Y79_17500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G4Y79_17505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4Y79_17510	COG4948	Mandelate Racemase Muconate Lactonizing
G4Y79_17525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4Y79_17530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4Y79_17540	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G4Y79_17550	COG2068	MobA-Related Protein
G4Y79_17580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G4Y79_17580	COG3608	succinylglutamate desuccinylase aspartoacylase
G4Y79_17590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4Y79_17595	COG1920	GTP binding
G4Y79_17600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G4Y79_17605	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G4Y79_17605	COG0778	Nitroreductase
G4Y79_17610	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G4Y79_17610	COG0778	Nitroreductase
G4Y79_17620	COG0402	S-adenosylhomocysteine deaminase activity
G4Y79_17640	COG0463	Glycosyl transferase, family 2
G4Y79_17645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G4Y79_17650	COG0537	adenosine 5'-monophosphoramidase activity
G4Y79_17655	COG0549	Belongs to the carbamate kinase family
G4Y79_17675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G4Y79_17690	COG0346	lactoylglutathione lyase activity
G4Y79_17695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4Y79_17700	COG0494	nUDIX hydrolase
G4Y79_17710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G4Y79_17720	COG0194	GDP metabolic process
G4Y79_17725	COG0354	folic acid binding
G4Y79_17755	COG3833	ABC-type maltose transport systems, permease component
G4Y79_17760	COG1175	transmembrane transport
G4Y79_17775	COG4585	Histidine kinase
G4Y79_17795	COG5002	protein histidine kinase activity
G4Y79_17800	COG0083	homoserine kinase activity
G4Y79_17805	COG1132	(ABC) transporter
G4Y79_17810	COG2813	Specifically methylates the guanine in position
G4Y79_17815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4Y79_17820	COG2226	methyltransferase
G4Y79_17830	COG0717	Belongs to the dCTP deaminase family
G4Y79_17835	COG0328	RNA-DNA hybrid ribonuclease activity
G4Y79_17850	COG0745	RESPONSE REGULATOR receiver
G4Y79_17885	COG5002	protein histidine kinase activity
G4Y79_17890	COG1940	carbohydrate kinase activity
G4Y79_17895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G4Y79_17905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G4Y79_17905	COG2226	methyltransferase
G4Y79_17905	COG0596	Alpha beta hydrolase
G4Y79_17910	COG3872	metal-dependent enzyme
G4Y79_17920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G4Y79_17920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G4Y79_17925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G4Y79_17935	COG1983	PspC domain protein
G4Y79_17940	COG1983	PspC domain protein
G4Y79_17950	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G4Y79_17955	COG0039	L-malate dehydrogenase activity
G4Y79_17960	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G4Y79_17985	COG0196	riboflavin kinase activity
G4Y79_17990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G4Y79_17995	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G4Y79_18000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G4Y79_18005	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G4Y79_18010	COG2740	Nucleic-acid-binding protein implicated in transcription termination
G4Y79_18015	COG0195	Participates in both transcription termination and antitermination
G4Y79_18055	COG2226	methyltransferase
G4Y79_18060	COG0438	transferase activity, transferring glycosyl groups
G4Y79_18070	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G4Y79_18075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G4Y79_18080	COG0516	GMP reductase activity
G4Y79_18080	COG0517	IMP dehydrogenase activity
G4Y79_18115	COG0183	Belongs to the thiolase family
G4Y79_18130	COG1132	(ABC) transporter
G4Y79_18135	COG1132	(ABC) transporter
G4Y79_18140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4Y79_18155	COG5002	protein histidine kinase activity
G4Y79_18195	COG1187	pseudouridine synthase activity
G4Y79_18210	COG0788	formyltetrahydrofolate deformylase activity
G4Y79_18215	COG2226	methyltransferase
G4Y79_18225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G4Y79_18240	COG0542	response to heat
G4Y79_18245	COG1472	Belongs to the glycosyl hydrolase 3 family
G4Y79_18265	COG2204	response regulator
G4Y79_18275	COG1077	Cell shape determining protein MreB Mrl
G4Y79_18290	COG0768	penicillin binding
G4Y79_18300	COG0850	regulation of cytokinetic process
G4Y79_18305	COG2894	cell division
G4Y79_18310	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G4Y79_18315	COG0772	Belongs to the SEDS family
G4Y79_18320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G4Y79_18345	COG5002	protein histidine kinase activity
G4Y79_18350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G4Y79_18355	COG0335	large ribosomal subunit rRNA binding
G4Y79_18365	COG1388	LysM domain
G4Y79_18365	COG3942	CHAP domain
G4Y79_18375	COG1968	undecaprenyl-diphosphatase activity
G4Y79_18380	COG2814	Major facilitator Superfamily
G4Y79_18395	COG0189	ligase activity
G4Y79_18400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G4Y79_18405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G4Y79_18410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4Y79_18415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4Y79_18420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G4Y79_18425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G4Y79_18430	COG0066	3-isopropylmalate dehydratase activity
G4Y79_18435	COG1653	transport
G4Y79_18440	COG1175	transmembrane transport
G4Y79_18445	COG0395	ABC-type sugar transport system, permease component
G4Y79_18455	COG1486	melibiose metabolic process
G4Y79_18465	COG0673	inositol 2-dehydrogenase activity
G4Y79_18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4Y79_18475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4Y79_18485	COG1605	Chorismate mutase
G4Y79_18485	COG0077	Prephenate dehydratase
G4Y79_18495	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G4Y79_18500	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G4Y79_18680	COG3320	Male sterility
G4Y79_18680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4Y79_18685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G4Y79_18745	COG1754	DNA topoisomerase type I activity
G4Y79_18745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4Y79_18750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4Y79_18755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4Y79_18785	COG0515	serine threonine protein kinase
G4Y79_18785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G4Y79_18860	COG2201	protein-glutamate methylesterase activity
G4Y79_18870	COG3685	Protein conserved in bacteria
G4Y79_18875	COG0109	protoheme IX farnesyltransferase activity
G4Y79_18880	COG3794	PFAM blue (type 1) copper domain protein
G4Y79_18910	COG1845	cytochrome c oxidase, subunit III
G4Y79_18910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4Y79_18920	COG2010	Cytochrome c
G4Y79_18920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G4Y79_18965	COG1160	GTP binding
G4Y79_18985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G4Y79_18990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4Y79_18990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4Y79_19020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4Y79_19045	COG1803	Methylglyoxal synthase
G4Y79_19070	COG0745	RESPONSE REGULATOR receiver
G4Y79_19075	COG0745	RESPONSE REGULATOR receiver
G4Y79_19080	COG5002	protein histidine kinase activity
G4Y79_19085	COG1543	Belongs to the glycosyl hydrolase 57 family
G4Y79_19090	COG0297	glycogen (starch) synthase activity
G4Y79_19095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G4Y79_19115	COG1668	transmembrane transport
G4Y79_19120	COG4152	abc transporter atp-binding protein
G4Y79_19130	COG0741	lytic transglycosylase activity
G4Y79_19150	COG1331	Highly conserved protein containing a thioredoxin domain
G4Y79_19160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4Y79_19165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G4Y79_19170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G4Y79_19185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G4Y79_19190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G4Y79_19195	COG0509	glycine decarboxylation via glycine cleavage system
G4Y79_19205	COG1999	signal sequence binding
G4Y79_19210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4Y79_19215	COG0343	queuine tRNA-ribosyltransferase activity
G4Y79_19220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G4Y79_19230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4Y79_19245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4Y79_19265	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G4Y79_19280	COG0656	L-ascorbic acid biosynthetic process
G4Y79_19295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4Y79_19300	COG1120	ATPase activity
G4Y79_19305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4Y79_19310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4Y79_19325	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_19370	COG0346	lactoylglutathione lyase activity
G4Y79_19380	COG4221	oxidoreductase activity
G4Y79_19385	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
G4Y79_19395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4Y79_19400	COG2217	Heavy metal translocating P-type atpase
G4Y79_19435	COG0604	alcohol dehydrogenase
G4Y79_19460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4Y79_19465	COG0439	Biotin carboxylase
G4Y79_19470	COG5016	pyruvate
G4Y79_19470	COG0511	ligase activity, forming carbon-carbon bonds
G4Y79_19510	COG4221	oxidoreductase activity
G4Y79_19520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G4Y79_19525	COG0205	6-phosphofructokinase activity
G4Y79_19535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G4Y79_19575	COG0653	protein targeting
G4Y79_19585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G4Y79_19595	COG5002	protein histidine kinase activity
G4Y79_19605	COG3118	belongs to the thioredoxin family
G4Y79_19610	COG1420	regulation of RNA biosynthetic process
G4Y79_19615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G4Y79_19620	COG0443	Heat shock 70 kDa protein
G4Y79_19625	COG0484	heat shock protein binding
G4Y79_19630	COG2264	protein methyltransferase activity
G4Y79_19640	COG2226	methyltransferase
G4Y79_19645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G4Y79_19650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G4Y79_19655	COG0539	negative regulation of cytoplasmic translation
G4Y79_19665	COG0539	negative regulation of cytoplasmic translation
G4Y79_19670	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G4Y79_19690	COG0628	permease
G4Y79_19700	COG1185	polyribonucleotide nucleotidyltransferase activity
G4Y79_19715	COG0442	prolyl-tRNA aminoacylation
G4Y79_19725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G4Y79_19735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G4Y79_19740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G4Y79_19750	COG0356	it plays a direct role in the translocation of protons across the membrane
G4Y79_19760	COG1007	ATP synthesis coupled electron transport
G4Y79_19765	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G4Y79_19775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G4Y79_19790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G4Y79_19795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G4Y79_19810	COG0596	Alpha beta hydrolase
G4Y79_19820	COG0456	acetyltransferase
G4Y79_19830	COG2373	Large extracellular alpha-helical protein
G4Y79_19845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4Y79_19855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G4Y79_19875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G4Y79_19880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G4Y79_19895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4Y79_19900	COG0772	Belongs to the SEDS family
G4Y79_19905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G4Y79_19910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4Y79_19925	COG0275	rRNA processing
G4Y79_19930	COG2001	Belongs to the MraZ family
G4Y79_19945	COG0322	excinuclease ABC activity
G4Y79_19970	COG3584	3D domain protein
G4Y79_19970	COG1388	LysM domain
G4Y79_19975	COG0318	PFAM AMP-dependent synthetase and ligase
G4Y79_19980	COG1929	Belongs to the glycerate kinase type-1 family
G4Y79_19990	COG2202	Pas domain
G4Y79_19990	COG2205	protein histidine kinase activity
G4Y79_19995	COG2202	Pas domain
G4Y79_19995	COG2205	protein histidine kinase activity
G4Y79_20000	COG3437	response regulator, receiver
G4Y79_20000	COG2205	protein histidine kinase activity
G4Y79_20000	COG3850	Histidine kinase
G4Y79_20000	COG4999	Histidine kinase
G4Y79_20005	COG1597	lipid kinase activity
G4Y79_20010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G4Y79_20015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G4Y79_20035	COG0667	Aldo Keto reductase
G4Y79_20065	COG0318	PFAM AMP-dependent synthetase and ligase
G4Y79_20085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4Y79_20135	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_20140	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_20145	COG1024	Enoyl-CoA hydratase
G4Y79_20145	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4Y79_20150	COG0183	Belongs to the thiolase family
G4Y79_20160	COG0346	lactoylglutathione lyase activity
G4Y79_20165	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
G4Y79_20175	COG0277	FAD linked oxidase domain protein
G4Y79_20195	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G4Y79_20210	COG3012	SEC-C Motif Domain Protein
G4Y79_20215	COG2966	Psort location CytoplasmicMembrane, score
G4Y79_20225	COG2124	cytochrome p450
G4Y79_20230	COG0366	Alpha amylase catalytic
G4Y79_20235	COG0716	FMN binding
G4Y79_20245	COG0124	histidyl-tRNA synthetase
G4Y79_20250	COG0535	radical SAM domain protein
G4Y79_20260	COG0247	lactate metabolic process
G4Y79_20260	COG2181	nitrate reductase activity
G4Y79_20265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4Y79_20270	COG0022	dehydrogenase e1 component
G4Y79_20275	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4Y79_20310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4Y79_20320	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G4Y79_20325	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G4Y79_20330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G4Y79_20360	COG1609	Transcriptional regulator
G4Y79_20370	COG1175	transmembrane transport
G4Y79_20375	COG0395	ABC-type sugar transport system, permease component
G4Y79_20385	COG4166	transmembrane transport
G4Y79_20390	COG0601	transmembrane transport
G4Y79_20395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_20395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4Y79_20400	COG1940	carbohydrate kinase activity
G4Y79_20405	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
G4Y79_20425	COG0395	ABC-type sugar transport system, permease component
G4Y79_20455	COG0463	Glycosyl transferase, family 2
G4Y79_20535	COG0823	Involved in the tonB-independent uptake of proteins
G4Y79_20640	COG1611	Belongs to the LOG family
G4Y79_20650	COG2261	transglycosylase associated protein
G4Y79_20675	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G4Y79_20680	COG0598	Magnesium transport protein CorA
G4Y79_20695	COG2010	Cytochrome c
G4Y79_20715	COG1138	Cytochrome C-type biogenesis protein
G4Y79_20725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4Y79_20745	COG1131	(ABC) transporter
G4Y79_20965	COG0455	bacterial-type flagellum organization
G4Y79_20970	COG2176	DNA-directed DNA polymerase activity
G4Y79_20970	COG5002	protein histidine kinase activity
G4Y79_21005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4Y79_21020	COG0789	Transcriptional regulator
G4Y79_21045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G4Y79_21050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G4Y79_21055	COG0072	phenylalanine-tRNA ligase activity
G4Y79_21065	COG1254	Belongs to the acylphosphatase family
G4Y79_21075	COG1024	Enoyl-CoA hydratase
G4Y79_21110	COG1234	tRNA 3'-trailer cleavage
G4Y79_21115	COG4122	O-methyltransferase activity
G4Y79_21125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4Y79_21135	COG0359	binds to the 23S rRNA
G4Y79_21155	COG0783	Belongs to the Dps family
G4Y79_21160	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_21165	COG1722	exodeoxyribonuclease VII activity
G4Y79_21170	COG1570	exodeoxyribonuclease VII activity
G4Y79_21185	COG1268	BioY protein
G4Y79_21190	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G4Y79_21195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4Y79_21200	COG0300	oxidoreductase activity
G4Y79_21210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G4Y79_21215	COG0003	Pfam Anion-transporting ATPase
G4Y79_21250	COG0702	epimerase
G4Y79_21255	COG0519	Catalyzes the synthesis of GMP from XMP
G4Y79_21270	COG1573	uracil-dna glycosylase
G4Y79_21280	COG0745	RESPONSE REGULATOR receiver
G4Y79_21285	COG5002	protein histidine kinase activity
G4Y79_21295	COG0589	response to stress
G4Y79_21315	COG5002	protein histidine kinase activity
G4Y79_21320	COG0745	RESPONSE REGULATOR receiver
G4Y79_21330	COG1132	(ABC) transporter
G4Y79_21335	COG5322	oxidoreductase activity
G4Y79_21345	COG0596	Alpha beta hydrolase
G4Y79_21375	COG0515	serine threonine protein kinase
G4Y79_21375	COG2815	serine threonine protein kinase
G4Y79_21415	COG2363	Small membrane protein
G4Y79_21445	COG0515	serine threonine protein kinase
G4Y79_21445	COG2815	serine threonine protein kinase
G4Y79_21450	COG0542	response to heat
G4Y79_21455	COG0515	serine threonine protein kinase
G4Y79_21455	COG2815	serine threonine protein kinase
G4Y79_21465	COG2267	carboxylic ester hydrolase activity
G4Y79_21470	COG0697	spore germination
G4Y79_21475	COG1051	belongs to the nudix hydrolase family
G4Y79_21505	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G4Y79_21510	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G4Y79_21515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G4Y79_21520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G4Y79_21595	COG0038	chloride channel
G4Y79_21600	COG1621	beta-fructofuranosidase activity
G4Y79_21630	COG1120	ATPase activity
G4Y79_21640	COG0501	Belongs to the peptidase M48B family
G4Y79_21645	COG0484	heat shock protein binding
G4Y79_21650	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G4Y79_21650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G4Y79_21655	COG1162	GTPase activity
G4Y79_21660	COG0515	serine threonine protein kinase
G4Y79_21660	COG2815	serine threonine protein kinase
G4Y79_21670	COG0242	peptide deformylase activity
G4Y79_21680	COG4946	Tricorn protease homolog
G4Y79_21680	COG0823	Involved in the tonB-independent uptake of proteins
G4Y79_21680	COG1506	peptidase
G4Y79_21685	COG1957	nucleoside hydrolase
G4Y79_21700	COG0357	Ribosomal RNA small subunit methyltransferase G
G4Y79_21710	COG1253	flavin adenine dinucleotide binding
G4Y79_21725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4Y79_21735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G4Y79_21765	COG5002	protein histidine kinase activity
G4Y79_21775	COG0542	response to heat
G4Y79_21785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G4Y79_21785	COG0515	serine threonine protein kinase
G4Y79_21795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G4Y79_21820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4Y79_21840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4Y79_21850	COG0569	domain protein
G4Y79_21850	COG0189	ligase activity
G4Y79_21855	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_21900	COG3852	Histidine kinase
G4Y79_21905	COG2205	protein histidine kinase activity
G4Y79_21910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_21935	COG0222	ribosome binding
G4Y79_21940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G4Y79_21945	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G4Y79_21970	COG1132	(ABC) transporter
G4Y79_21975	COG1132	(ABC) transporter
G4Y79_22005	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G4Y79_22030	COG0436	Aminotransferase
G4Y79_22075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G4Y79_22115	COG0460	homoserine dehydrogenase
G4Y79_22155	COG2205	protein histidine kinase activity
G4Y79_22160	COG2223	nitrite transmembrane transporter activity
G4Y79_22165	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
G4Y79_22180	COG1175	transmembrane transport
G4Y79_22185	COG0395	ABC-type sugar transport system, permease component
G4Y79_22265	COG0765	amino acid transport
G4Y79_22275	COG1595	DNA-templated transcription, initiation
G4Y79_22285	COG0493	'glutamate synthase
G4Y79_22290	COG0006	proline dipeptidase activity
G4Y79_22310	COG2205	protein histidine kinase activity
G4Y79_22315	COG5002	protein histidine kinase activity
G4Y79_22325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G4Y79_22330	COG2201	protein-glutamate methylesterase activity
G4Y79_22335	COG0745	RESPONSE REGULATOR receiver
G4Y79_22350	COG4585	Histidine kinase
G4Y79_22350	COG2203	Gaf domain
G4Y79_22365	COG5002	protein histidine kinase activity
G4Y79_22365	COG0784	Response regulator, receiver
G4Y79_22370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G4Y79_22375	COG2205	protein histidine kinase activity
G4Y79_22405	COG0708	Exodeoxyribonuclease III
G4Y79_22420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G4Y79_22430	COG2388	GCN5-related N-acetyl-transferase
G4Y79_22445	COG2814	Major facilitator Superfamily
G4Y79_22470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G4Y79_22470	COG3743	rRNA binding
G4Y79_22485	COG0542	response to heat
G4Y79_22490	COG0539	negative regulation of cytoplasmic translation
G4Y79_22495	COG0542	response to heat
G4Y79_22510	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_22525	COG3214	Protein conserved in bacteria
G4Y79_22530	COG5002	protein histidine kinase activity
G4Y79_22530	COG2176	DNA-directed DNA polymerase activity
G4Y79_22550	COG1408	metallophosphoesterase
G4Y79_22555	COG2318	DinB family
G4Y79_22565	COG0673	inositol 2-dehydrogenase activity
G4Y79_22575	COG0667	Aldo Keto reductase
G4Y79_22600	COG1028	Short-chain dehydrogenase reductase Sdr
G4Y79_22605	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G4Y79_22615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4Y79_22620	COG0484	heat shock protein binding
G4Y79_22625	COG1247	-acetyltransferase
G4Y79_22630	COG1363	Peptidase, m42
G4Y79_22655	COG0459	protein refolding
G4Y79_22660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G4Y79_22665	COG1569	PIN domain
G4Y79_22670	COG3311	Transcriptional regulator
G4Y79_22675	COG0515	serine threonine protein kinase
G4Y79_22675	COG2815	serine threonine protein kinase
G4Y79_22735	COG0187	DNA topoisomerase II activity
G4Y79_22780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G4Y79_22790	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G4Y79_22800	COG0697	spore germination
G4Y79_22805	COG1522	sequence-specific DNA binding
G4Y79_22835	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4Y79_22840	COG0022	dehydrogenase e1 component
G4Y79_22840	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4Y79_22845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4Y79_22860	COG2814	Major facilitator Superfamily
G4Y79_22890	COG0495	leucyl-tRNA aminoacylation
G4Y79_22910	COG5016	pyruvate
G4Y79_22910	COG0511	ligase activity, forming carbon-carbon bonds
G4Y79_22920	COG0439	Biotin carboxylase
G4Y79_22925	COG1316	TRANSCRIPTIONal
G4Y79_22950	COG1047	Peptidyl-prolyl cis-trans
G4Y79_22955	COG0424	maF-like protein
G4Y79_22985	COG1525	nuclease
G4Y79_23000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4Y79_23005	COG4597	amino acid ABC transporter
G4Y79_23010	COG0765	amino acid transport
G4Y79_23015	COG1126	abc transporter atp-binding protein
G4Y79_23035	COG1482	cell wall glycoprotein biosynthetic process
G4Y79_23070	COG0473	3-isopropylmalate dehydrogenase activity
G4Y79_23100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4Y79_23105	COG0488	(ABC) transporter
G4Y79_23150	COG5002	protein histidine kinase activity
G4Y79_23195	COG0728	peptidoglycan biosynthetic process
G4Y79_23200	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G4Y79_23200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G4Y79_23205	COG0483	inositol monophosphate 1-phosphatase activity
G4Y79_23215	COG1309	transcriptional regulator
G4Y79_23230	COG0523	cobalamin synthesis protein
G4Y79_23255	COG0701	Predicted permease
G4Y79_23270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4Y79_23280	COG1546	Belongs to the CinA family
G4Y79_23280	COG1058	Belongs to the CinA family
G4Y79_23295	COG2272	Belongs to the type-B carboxylesterase lipase family
G4Y79_23300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4Y79_23310	COG0668	transmembrane transport
G4Y79_23345	COG0667	Aldo Keto reductase
G4Y79_23350	COG3616	Alanine racemase, N-terminal domain
G4Y79_23360	COG0784	Response regulator, receiver
G4Y79_23360	COG5002	protein histidine kinase activity
G4Y79_23360	COG2205	protein histidine kinase activity
G4Y79_23385	COG0406	alpha-ribazole phosphatase activity
G4Y79_23410	COG1193	negative regulation of DNA recombination
G4Y79_23420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4Y79_23425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G4Y79_23435	COG2301	Belongs to the HpcH HpaI aldolase family
G4Y79_23460	COG0668	transmembrane transport
G4Y79_23465	COG0668	transmembrane transport
G4Y79_23520	COG1063	alcohol dehydrogenase
G4Y79_23535	COG0367	asparagine synthase
G4Y79_23540	COG2814	Major facilitator Superfamily
G4Y79_23555	COG0758	DNA mediated transformation
G4Y79_23565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4Y79_23600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4Y79_23640	COG3118	belongs to the thioredoxin family
G4Y79_23650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4Y79_23655	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G4Y79_23660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4Y79_23670	COG2226	methyltransferase
G4Y79_23690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4Y79_23720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G4Y79_23725	COG0045	succinate-CoA ligase (ADP-forming) activity
G4Y79_23745	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
G4Y79_23750	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
G4Y79_23750	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
G4Y79_23785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4Y79_23795	COG2226	methyltransferase
G4Y79_23820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G4Y79_23825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G4Y79_23845	COG1764	response to oxidative stress
G4Y79_23860	COG0366	Alpha amylase catalytic
G4Y79_23875	COG0251	oxidation-reduction process
G4Y79_23905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G4Y79_23920	COG0745	RESPONSE REGULATOR receiver
G4Y79_23950	COG0134	indole-3-glycerol-phosphate synthase activity
G4Y79_23955	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G4Y79_23960	COG0745	RESPONSE REGULATOR receiver
G4Y79_23985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G4Y79_23985	COG0519	Catalyzes the synthesis of GMP from XMP
G4Y79_24000	COG1309	transcriptional regulator
G4Y79_24005	COG0438	transferase activity, transferring glycosyl groups
G4Y79_24040	COG1164	Oligoendopeptidase f
G4Y79_24055	COG1136	(ABC) transporter
G4Y79_24055	COG0577	efflux transmembrane transporter activity
G4Y79_24075	COG0584	glycerophosphoryl diester phosphodiesterase
G4Y79_24105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G4Y79_24120	COG1410	methionine synthase
G4Y79_24120	COG0646	methionine synthase
G4Y79_24140	COG0656	L-ascorbic acid biosynthetic process
G4Y79_24160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G4Y79_24165	COG2202	Pas domain
G4Y79_24165	COG2205	protein histidine kinase activity
G4Y79_24175	COG0768	penicillin binding
G4Y79_24220	COG0494	nUDIX hydrolase
G4Y79_24230	COG0129	dihydroxy-acid dehydratase activity
G4Y79_24260	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G4Y79_24260	COG0778	Nitroreductase
G4Y79_24285	COG1960	acyl-CoA dehydrogenase activity
G4Y79_24310	COG3848	Pyruvate phosphate dikinase
G4Y79_24310	COG0574	Belongs to the PEP-utilizing enzyme family
G4Y79_24315	COG0488	(ABC) transporter
G4Y79_24325	COG2323	membrane
G4Y79_24350	COG5183	chlorophyll binding
G4Y79_24350	COG2133	pyrroloquinoline quinone binding
G4Y79_24360	COG0671	phosphoesterase, PA-phosphatase related
G4Y79_24390	COG4585	Histidine kinase
G4Y79_24395	COG1051	belongs to the nudix hydrolase family
G4Y79_24410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4Y79_24420	COG0640	Transcriptional regulator
G4Y79_24425	COG1830	Aldolase